# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase_fungal PF17667.1 EGO18363.1 - 1.9e-24 86.2 0.0 2.2e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase DUF434 PF04256.12 EGO18365.1 - 0.026 14.2 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Transposase_21 PF02992.14 EGO18369.1 - 1.9e-08 33.8 0.4 2e-08 33.7 0.4 1.0 1 0 0 1 1 1 1 Transposase family tnp2 COesterase PF00135.28 EGO18370.1 - 1.1e-40 140.0 0.6 1e-30 107.1 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO18370.1 - 0.0031 17.4 0.1 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Flot PF15975.5 EGO18371.1 - 0.069 13.3 11.1 0.089 13.0 11.1 1.1 1 0 0 1 1 1 0 Flotillin YlqD PF11068.8 EGO18371.1 - 0.15 12.5 9.0 0.17 12.3 9.0 1.1 1 0 0 1 1 1 0 YlqD protein VIT1 PF01988.19 EGO18371.1 - 5.2 6.9 7.8 6 6.7 7.8 1.1 1 0 0 1 1 1 0 VIT family SprA-related PF12118.8 EGO18371.1 - 7.5 5.6 13.4 7.7 5.5 13.4 1.0 1 0 0 1 1 1 0 SprA-related family RIC3 PF15361.6 EGO18371.1 - 8.7 6.7 8.0 16 5.9 8.0 1.5 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 TMEM251 PF15190.6 EGO18375.1 - 0.074 13.0 0.7 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 251 Pkinase_fungal PF17667.1 EGO18378.1 - 0.00062 18.7 0.6 0.0008 18.3 0.6 1.1 1 0 0 1 1 1 1 Fungal protein kinase adh_short PF00106.25 EGO18380.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 EGO18380.1 - 0.26 10.8 0.0 0.3 10.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase gag-asp_proteas PF13975.6 EGO18381.1 - 0.00012 22.5 0.0 0.00016 22.1 0.0 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO18381.1 - 0.00016 22.3 0.0 0.00021 21.9 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO18381.1 - 0.00047 19.9 0.0 0.00054 19.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Cucumo_2B PF03263.13 EGO18381.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Cucumovirus protein 2B zf-CCHC PF00098.23 EGO18382.1 - 2.1e-08 33.9 5.9 3.4e-08 33.2 5.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO18382.1 - 0.012 15.5 3.0 0.012 15.5 3.0 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO18382.1 - 0.28 11.0 1.2 0.45 10.3 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO18383.1 - 3.9e-08 33.4 0.2 3.9e-08 33.4 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein BMFP PF04380.13 EGO18383.1 - 0.05 14.1 0.6 28 5.3 0.0 3.3 3 0 0 3 3 3 0 Membrane fusogenic activity zf-CCHC PF00098.23 EGO18384.1 - 4.6e-08 32.8 5.2 8.9e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO18384.1 - 3.4e-07 30.5 0.2 3.4e-07 30.5 0.2 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO18384.1 - 0.54 10.3 8.6 0.046 13.7 2.9 2.1 2 0 0 2 2 2 0 Zinc knuckle MMU163 PF17119.5 EGO18388.1 - 0.27 10.3 0.3 0.31 10.2 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis COesterase PF00135.28 EGO18390.1 - 1.7e-40 139.4 0.4 9.5e-32 110.5 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO18390.1 - 0.00076 19.4 0.0 0.0071 16.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF874 PF05917.11 EGO18391.1 - 3.5 6.6 10.4 5.3 6.0 10.4 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) YdfA_immunity PF12127.8 EGO18391.1 - 4.5 6.2 7.0 6.4 5.8 7.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial CK_II_beta PF01214.18 EGO18392.1 - 0.0086 15.9 0.2 0.0086 15.9 0.2 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Retrotrans_gag PF03732.17 EGO18394.1 - 7.2e-08 32.6 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Zn_Tnp_IS1 PF03811.13 EGO18397.1 - 0.022 14.5 0.9 0.055 13.2 0.1 1.9 2 0 0 2 2 2 0 InsA N-terminal domain zf-Dof PF02701.15 EGO18397.1 - 0.029 14.5 0.3 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger DDE_Tnp_ISL3 PF01610.17 EGO18401.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Transposase MULE PF10551.9 EGO18401.1 - 0.016 15.6 0.0 0.046 14.1 0.0 1.9 1 0 0 1 1 1 0 MULE transposase domain DUF1462 PF07315.11 EGO18402.1 - 0.059 13.7 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) ubiquitin PF00240.23 EGO18402.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family NAD_binding_4 PF07993.12 EGO18403.1 - 2.8e-27 95.5 0.0 3.7e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGO18403.1 - 3.4e-10 39.8 0.0 6.4e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO18403.1 - 4.8e-08 33.3 0.3 1.2e-07 32.0 0.2 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EGO18403.1 - 0.13 11.6 0.0 0.76 9.1 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO18403.1 - 0.19 10.7 0.0 1.3 8.0 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Tagatose_6_P_K PF08013.11 EGO18405.1 - 0.19 10.3 0.1 0.2 10.3 0.1 1.0 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase DUF4011 PF13195.6 EGO18406.1 - 0.012 15.5 4.6 0.021 14.8 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) YL1 PF05764.13 EGO18406.1 - 0.014 15.5 12.1 0.02 15.0 12.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SR-25 PF10500.9 EGO18406.1 - 0.064 12.9 10.5 0.095 12.3 10.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGO18406.1 - 0.084 12.2 11.2 0.12 11.7 11.2 1.2 1 0 0 1 1 1 0 BUD22 DUF2040 PF09745.9 EGO18406.1 - 0.11 12.5 7.4 0.077 13.1 5.7 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) CaKB PF03185.15 EGO18406.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit CDC45 PF02724.14 EGO18406.1 - 0.45 8.8 8.9 0.64 8.2 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 EGO18407.1 - 0.013 15.5 2.1 0.027 14.6 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4672 PF15716.5 EGO18407.1 - 0.34 10.5 2.2 3 7.4 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4672) Retrotrans_gag PF03732.17 EGO18409.1 - 4.1e-06 27.0 2.5 4.1e-06 27.0 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein MFS_1 PF07690.16 EGO18411.1 - 3.5e-24 85.4 61.0 3.4e-17 62.4 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pho86 PF11124.8 EGO18412.1 - 0.45 9.9 2.2 0.84 9.0 2.2 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 gag_pre-integrs PF13976.6 EGO18415.1 - 7.1e-11 41.8 0.1 1e-10 41.3 0.1 1.4 1 1 0 1 1 1 1 GAG-pre-integrase domain Rh5 PF18515.1 EGO18416.1 - 0.0016 17.8 7.8 0.0023 17.3 7.8 1.1 1 0 0 1 1 1 1 Rh5 coiled-coil domain Lipase_GDSL PF00657.22 EGO18416.1 - 0.079 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3038 PF11237.8 EGO18416.1 - 0.25 11.4 1.5 0.43 10.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DDE_Tnp_4 PF13359.6 EGO18422.1 - 2.4e-06 27.3 0.0 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Rnf-Nqr PF02508.14 EGO18423.1 - 0.0037 17.3 0.0 0.0052 16.8 0.0 1.1 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein Trp_halogenase PF04820.14 EGO18424.1 - 7.7e-05 21.7 0.2 0.14 11.0 0.0 2.9 2 1 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 EGO18424.1 - 0.00025 20.6 0.0 0.00068 19.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO18424.1 - 0.035 13.4 0.1 0.39 9.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KDZ PF18758.1 EGO18427.1 - 1.1e-17 64.4 0.3 5e-12 45.9 0.0 2.5 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase zf-CCHC_4 PF14392.6 EGO18428.1 - 0.081 12.7 1.6 0.14 11.9 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle PIN_12 PF16289.5 EGO18430.1 - 0.025 15.1 1.7 0.028 14.9 0.4 1.8 2 1 0 2 2 2 0 PIN domain DUF2791 PF10923.8 EGO18430.1 - 0.049 12.5 0.5 0.076 11.8 0.5 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Plavaka PF18759.1 EGO18433.1 - 4.2e-85 285.8 0.5 6.1e-85 285.3 0.1 1.5 2 0 0 2 2 2 1 Plavaka transposase CBFD_NFYB_HMF PF00808.23 EGO18434.1 - 3.9e-08 33.5 0.1 6.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 EGO18434.1 - 0.00037 20.6 11.5 0.00046 20.3 11.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-T_C PF15511.6 EGO18434.1 - 0.016 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PPP4R2 PF09184.11 EGO18434.1 - 0.3 10.6 11.5 0.36 10.4 11.5 1.3 1 0 0 1 1 1 0 PPP4R2 KDZ PF18758.1 EGO18435.1 - 4.7e-52 176.8 4.9 6e-49 166.7 0.4 2.1 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Strep_his_triad PF04270.13 EGO18435.1 - 0.055 13.5 0.6 0.23 11.5 0.3 2.3 3 0 0 3 3 3 0 Streptococcal histidine triad protein p450 PF00067.22 EGO18438.1 - 5e-70 236.5 0.0 6.2e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO18439.1 - 0.00013 20.8 0.0 0.00013 20.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO18440.1 - 2.6e-47 161.6 0.0 3.2e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EGO18441.1 - 0.055 12.7 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ELF PF03317.13 EGO18442.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 ELF protein ABC_membrane PF00664.23 EGO18443.1 - 1.8e-57 195.1 23.5 4.5e-30 105.2 6.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO18443.1 - 1.8e-49 167.8 0.0 5e-27 95.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO18443.1 - 1.1e-06 28.2 2.2 0.0018 17.8 1.2 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO18443.1 - 6.9e-06 26.1 0.5 0.04 14.0 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGO18443.1 - 1.5e-05 25.6 0.9 0.26 11.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO18443.1 - 0.00013 22.4 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO18443.1 - 0.00018 21.4 0.4 0.6 10.0 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EGO18443.1 - 0.00033 20.3 2.2 0.2 11.4 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGO18443.1 - 0.00044 20.1 0.7 1.4 8.7 0.1 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 EGO18443.1 - 0.0025 17.5 0.0 0.82 9.3 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EGO18443.1 - 0.0038 17.5 4.3 6.5 7.0 0.2 4.1 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EGO18443.1 - 0.006 15.9 0.5 1.8 7.8 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EGO18443.1 - 0.011 15.4 2.1 3 7.5 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGO18443.1 - 0.021 14.4 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGO18443.1 - 0.028 14.7 0.5 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EGO18443.1 - 0.03 14.3 0.1 0.86 9.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2716 PF10898.8 EGO18443.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) AAA_7 PF12775.7 EGO18443.1 - 0.042 13.4 0.2 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EGO18443.1 - 0.044 13.8 1.3 4.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EGO18443.1 - 0.06 13.1 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGO18443.1 - 0.067 12.1 1.8 2.8 6.7 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 EGO18443.1 - 0.19 11.8 2.1 0.8 9.8 0.2 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EGO18443.1 - 0.24 11.1 1.0 21 4.8 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 EGO18443.1 - 0.28 10.8 1.3 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGO18443.1 - 0.72 9.8 2.1 1.5 8.7 0.3 2.2 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 EGO18443.1 - 1.1 9.0 3.3 52 3.5 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EzrA PF06160.12 EGO18446.1 - 0.24 9.5 0.0 0.26 9.4 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ssl1 PF04056.14 EGO18447.1 - 0.059 13.2 0.1 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Ssl1-like SNAD3 PF18749.1 EGO18448.1 - 0.066 12.4 0.5 0.12 11.6 0.5 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 DUF913 PF06025.12 EGO18448.1 - 1 8.3 3.6 3 6.7 3.6 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 EGO18448.1 - 9.6 6.7 10.2 5.3 7.5 0.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM252 PF15664.5 EGO18449.1 - 0.059 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF3527 PF12043.8 EGO18451.1 - 0.0029 17.2 0.1 0.0032 17.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) BUD22 PF09073.10 EGO18453.1 - 0.0031 16.9 10.8 0.0045 16.4 10.8 1.3 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 EGO18453.1 - 0.013 15.6 13.6 0.013 15.6 13.6 1.4 2 0 0 2 2 2 0 YL1 nuclear protein SR-25 PF10500.9 EGO18453.1 - 0.02 14.5 11.4 0.033 13.8 11.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGO18453.1 - 2.7 6.2 12.8 3.8 5.7 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EGO18453.1 - 4.1 5.4 15.0 6.1 4.8 15.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EGO18453.1 - 5.4 6.0 9.2 1.8 7.5 6.7 1.5 2 0 0 2 2 2 0 Pes-10 Abhydrolase_3 PF07859.13 EGO18454.1 - 1.1e-13 51.5 0.0 2.2e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGO18454.1 - 6.1e-08 32.0 0.0 3.1e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 EGO18454.1 - 2.4e-05 23.5 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 EGO18454.1 - 3.2e-05 23.0 0.0 4.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGO18454.1 - 0.043 13.1 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 RhoGEF PF00621.20 EGO18455.1 - 0.00064 20.0 0.0 0.00069 19.9 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.20 EGO18456.1 - 3.7e-47 160.9 11.3 3.7e-47 160.9 11.3 1.6 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 EGO18456.1 - 1.2e-10 41.3 0.0 3.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EGO18456.1 - 1.8e-09 37.3 0.1 4.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 STAS domain Fungal_trans PF04082.18 EGO18461.1 - 5.1e-13 48.7 3.1 3.7e-12 45.9 3.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Hva1_TUDOR PF11160.8 EGO18463.1 - 0.00021 21.4 1.7 0.00023 21.3 0.7 1.6 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Auxin_repressed PF05564.12 EGO18464.1 - 0.38 11.4 2.2 0.57 10.9 0.9 2.0 2 0 0 2 2 2 0 Dormancy/auxin associated protein Asp PF00026.23 EGO18466.1 - 2e-38 132.6 5.9 6e-37 127.7 5.9 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGO18466.1 - 1.7e-05 25.3 0.9 0.0072 16.9 0.4 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EGO18466.1 - 0.00024 21.6 0.6 0.093 13.3 0.1 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EGO18466.1 - 0.0013 19.0 2.2 0.2 11.9 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Retrotrans_gag PF03732.17 EGO18468.1 - 1.5e-06 28.4 0.0 6.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO18468.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) KDZ PF18758.1 EGO18473.1 - 2.7e-12 46.8 4.1 2.6e-09 37.0 3.6 2.4 1 1 1 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Hid1 PF12722.7 EGO18473.1 - 0.019 13.1 0.2 0.027 12.6 0.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4939 PF16297.5 EGO18479.1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Bac_chlorC PF02043.17 EGO18479.1 - 0.12 12.4 1.5 15 5.7 0.0 2.9 2 1 1 3 3 3 0 Bacteriochlorophyll C binding protein CxC2 PF18803.1 EGO18483.1 - 0.0003 20.9 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF2228 PF10228.9 EGO18484.1 - 0.078 12.7 0.8 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) CDC50 PF03381.15 EGO18487.1 - 0.079 12.5 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family RTC PF01137.21 EGO18488.1 - 0.096 11.9 0.0 0.3 10.2 0.0 1.6 1 1 1 2 2 2 0 RNA 3'-terminal phosphate cyclase CxC2 PF18803.1 EGO18492.1 - 1.2e-28 99.4 0.0 2.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EGO18492.1 - 0.042 14.0 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Staphylcoagulse PF04022.12 EGO18494.1 - 0.23 11.0 0.3 0.48 10.0 0.3 1.5 1 0 0 1 1 1 0 Staphylocoagulase repeat Dicty_REP PF05086.12 EGO18495.1 - 0.5 8.3 1.7 0.49 8.3 1.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGO18495.1 - 0.89 9.5 19.6 1.2 9.1 19.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGO18495.1 - 1.4 8.9 14.0 2.4 8.2 14.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGO18495.1 - 9.7 4.2 15.4 13 3.9 15.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PIF1 PF05970.14 EGO18496.1 - 1.1e-08 34.7 0.0 1.3e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 EGO18496.1 - 0.00014 22.3 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO18496.1 - 0.0027 17.4 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGO18496.1 - 0.0086 15.8 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EGO18496.1 - 0.0088 15.1 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGO18496.1 - 0.015 15.6 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGO18496.1 - 0.03 13.7 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EGO18496.1 - 0.039 13.1 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 EGO18496.1 - 0.048 12.9 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGO18496.1 - 0.055 13.8 0.0 0.066 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 EGO18496.1 - 0.059 13.3 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Torsin PF06309.11 EGO18496.1 - 0.065 13.3 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Torsin IIGP PF05049.13 EGO18496.1 - 0.22 10.6 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Alpha_kinase PF02816.18 EGO18497.1 - 4.5e-18 66.0 0.0 5.1e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.16 EGO18498.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1786 PF08735.10 EGO18500.1 - 0.096 12.0 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Hydrolase_4 PF12146.8 EGO18503.1 - 1.4e-12 47.4 0.1 1.3e-09 37.7 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGO18503.1 - 3.7e-10 39.9 0.5 6.6e-10 39.0 0.5 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGO18503.1 - 2.2e-09 38.3 1.0 3.1e-09 37.7 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO18503.1 - 6.2e-06 26.1 0.0 0.0092 15.6 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO18503.1 - 0.00027 20.5 0.1 0.06 12.8 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PHB_depo_C PF06850.11 EGO18503.1 - 0.0083 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 PHB de-polymerase C-terminus AA_permease_2 PF13520.6 EGO18504.1 - 5.3e-63 213.3 58.5 6.5e-63 213.0 58.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO18504.1 - 5.8e-11 41.7 50.0 8.2e-11 41.2 50.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1129 PF06570.11 EGO18504.1 - 5.9 6.3 6.1 19 4.7 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Intg_mem_TP0381 PF09529.10 EGO18506.1 - 0.029 13.9 0.2 0.035 13.6 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) UbiA PF01040.18 EGO18508.1 - 5.2e-48 163.6 17.9 6.6e-48 163.2 17.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RseC_MucC PF04246.12 EGO18508.1 - 0.018 15.0 3.6 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1129 PF06570.11 EGO18508.1 - 2 7.9 5.2 0.99 8.9 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) FAD_binding_3 PF01494.19 EGO18509.1 - 7.8e-65 219.4 0.0 1e-64 219.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO18509.1 - 4.5e-07 29.4 0.2 0.0053 16.0 0.0 2.7 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO18509.1 - 0.00012 21.8 0.2 0.0025 17.4 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO18509.1 - 0.00013 22.5 0.2 0.0044 17.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO18509.1 - 0.00027 19.9 0.0 0.00052 19.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EGO18509.1 - 0.00043 20.5 0.1 0.0015 18.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGO18509.1 - 0.0079 15.5 0.0 0.074 12.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO18509.1 - 0.015 15.3 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGO18509.1 - 0.024 13.3 0.1 0.2 10.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EGO18509.1 - 0.085 11.9 0.1 0.2 10.7 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 EGO18510.1 - 3.5e-49 167.6 47.2 2.2e-47 161.7 47.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5423 PF17461.2 EGO18510.1 - 0.3 9.9 3.7 0.16 10.8 1.5 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5423) GFO_IDH_MocA PF01408.22 EGO18511.1 - 8.3e-22 78.3 0.0 1.3e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 EGO18511.1 - 0.0013 19.4 0.0 0.0029 18.3 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAD_binding_3 PF01494.19 EGO18512.1 - 2.9e-73 247.1 0.0 6.6e-72 242.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO18512.1 - 1.3e-21 77.4 0.0 2.3e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EGO18512.1 - 1.1e-05 24.4 0.1 1.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGO18512.1 - 2.5e-05 23.6 0.1 4.5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGO18512.1 - 5.1e-05 22.5 0.5 7.9e-05 21.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGO18512.1 - 6.7e-05 22.4 0.2 0.00011 21.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EGO18512.1 - 9.7e-05 22.1 0.1 0.00018 21.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO18512.1 - 0.00021 20.6 0.0 0.00041 19.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO18512.1 - 0.00041 19.6 0.3 0.00068 18.8 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO18512.1 - 0.00049 20.6 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO18512.1 - 0.0006 19.1 0.2 0.001 18.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO18512.1 - 0.001 19.3 0.1 0.0023 18.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGO18512.1 - 0.0042 16.2 0.4 0.0083 15.2 0.4 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGO18512.1 - 0.0052 16.1 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGO18512.1 - 0.065 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGO18512.1 - 0.15 10.9 0.0 0.29 9.9 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Alpha_kinase PF02816.18 EGO18513.1 - 8e-18 65.2 0.0 9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.16 EGO18515.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Transposase_21 PF02992.14 EGO18520.1 - 5e-06 25.9 0.0 7.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Retrotrans_gag PF03732.17 EGO18522.1 - 7.5e-06 26.1 1.3 4.1e-05 23.8 1.3 2.3 1 1 0 1 1 1 1 Retrotransposon gag protein Pkinase_fungal PF17667.1 EGO18523.1 - 4.8e-28 98.1 0.0 6.4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Alpha-amylase PF00128.24 EGO18524.1 - 3.3e-20 72.9 10.2 6.7e-20 71.9 2.1 3.0 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EGO18524.1 - 9e-16 58.3 0.1 1.5e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGO18524.1 - 4.8e-07 29.5 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO18524.1 - 3.1e-06 27.7 0.0 6.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Histone PF00125.24 EGO18525.1 - 3.2e-21 76.1 2.9 4e-21 75.7 2.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO18525.1 - 3e-05 24.2 0.1 6.4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGO18525.1 - 0.00034 21.1 0.0 0.0006 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGO18525.1 - 0.017 15.2 0.3 0.02 14.9 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein DUF1018 PF06252.12 EGO18525.1 - 0.031 15.3 0.8 0.043 14.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Pkinase_fungal PF17667.1 EGO18526.1 - 1.5e-19 70.1 0.0 1.6e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Plavaka PF18759.1 EGO18527.1 - 1.4e-23 83.7 0.0 3.5e-17 62.6 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase Pkinase_fungal PF17667.1 EGO18529.1 - 6.5e-24 84.4 0.0 7.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase MMU163 PF17119.5 EGO18530.1 - 0.13 11.4 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis zf-CCHC PF00098.23 EGO18533.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO18533.1 - 0.0082 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO18533.1 - 0.011 15.3 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger domain Chromo PF00385.24 EGO18538.1 - 1.5e-06 28.0 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5551 PF17705.1 EGO18541.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5551) zinc_ribbon_9 PF14369.6 EGO18541.1 - 0.2 11.9 5.2 0.38 11.0 3.5 2.1 1 1 1 2 2 2 0 zinc-ribbon YonK PF09642.10 EGO18546.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 YonK protein Myb_DNA-bind_3 PF12776.7 EGO18548.1 - 0.00087 20.2 0.0 0.0019 19.1 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SOGA PF11365.8 EGO18550.1 - 0.045 14.9 0.2 0.18 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein SOGA Tox-PL-2 PF15643.6 EGO18550.1 - 0.13 12.4 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Papain fold toxin 2 Pkinase_fungal PF17667.1 EGO18551.1 - 5.4e-30 104.5 0.0 7.1e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 EGO18553.1 - 7.6e-43 143.7 17.8 1.8e-08 34.9 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EGO18553.1 - 6.1e-30 104.1 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EGO18553.1 - 3.8e-08 33.5 0.0 0.089 13.1 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EGO18553.1 - 6.6e-05 22.7 0.0 0.019 14.9 0.0 2.6 2 0 0 2 2 2 2 LisH Nup160 PF11715.8 EGO18553.1 - 0.00023 19.9 1.3 3.6 6.1 0.0 3.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PAP2 PF01569.21 EGO18554.1 - 4.7e-11 42.6 4.7 5.9e-11 42.3 4.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGO18554.1 - 0.77 9.9 2.8 3.4 7.8 0.5 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF2418 PF10332.9 EGO18555.1 - 5e-27 94.3 0.0 1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) zf-C2H2 PF00096.26 EGO18556.1 - 5.6e-13 48.6 11.7 5.3e-07 29.8 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO18556.1 - 3.4e-10 39.9 17.1 1.4e-08 34.8 2.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO18556.1 - 6e-09 36.0 9.3 0.0005 20.7 0.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EGO18556.1 - 8.1e-07 29.6 1.0 0.012 16.2 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EGO18556.1 - 1e-05 25.7 0.1 0.054 13.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO18556.1 - 0.00058 20.2 0.2 0.052 13.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-CGNR PF11706.8 EGO18556.1 - 0.0052 16.6 3.2 1.2 9.1 0.5 2.3 2 0 0 2 2 2 2 CGNR zinc finger zf-C2H2_6 PF13912.6 EGO18556.1 - 0.006 16.6 9.3 0.049 13.6 0.2 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGO18556.1 - 0.075 12.8 11.5 2.1 8.2 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Toxin_8 PF07365.12 EGO18556.1 - 0.085 13.0 5.0 1.3 9.3 1.0 2.2 2 0 0 2 2 2 0 Alpha conotoxin precursor zf-C2H2_11 PF16622.5 EGO18556.1 - 0.096 12.5 4.7 1.2 8.9 1.5 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type FBPase PF00316.20 EGO18557.1 - 2.6e-74 248.8 0.2 3.3e-74 248.5 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EGO18557.1 - 0.0009 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Pmp3 PF01679.17 EGO18558.1 - 8e-15 54.8 2.8 1.1e-14 54.3 2.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator rve_3 PF13683.6 EGO18558.1 - 0.014 15.1 0.7 0.014 15.1 0.7 2.0 2 0 0 2 2 2 0 Integrase core domain NapE PF06796.11 EGO18558.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE PNGaseA PF12222.8 EGO18559.1 - 1.2e-137 459.3 6.7 1.7e-137 458.8 6.7 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_45 PF14947.6 EGO18559.1 - 0.031 14.3 0.4 0.065 13.2 0.4 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix FTHFS PF01268.19 EGO18560.1 - 9e-256 849.4 0.1 1.7e-255 848.5 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EGO18560.1 - 2.6e-64 215.4 0.8 2.6e-64 215.4 0.8 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGO18560.1 - 4.3e-37 126.9 0.2 8.5e-37 126.0 0.2 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EGO18560.1 - 0.033 13.1 0.1 0.067 12.1 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family tRNA-synt_2d PF01409.20 EGO18561.1 - 1.2e-43 149.4 0.1 5.2e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGO18561.1 - 9.3e-24 83.7 0.0 1.9e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain ETC_C1_NDUFA5 PF04716.14 EGO18562.1 - 3.5e-28 97.2 0.1 5.7e-28 96.5 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region E7 PF00527.18 EGO18564.1 - 0.0082 16.3 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 E7 protein, Early protein GCIP PF13324.6 EGO18565.1 - 4.4e-14 52.7 1.5 6.6e-14 52.1 1.5 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting MutS_II PF05188.17 EGO18565.1 - 0.014 15.7 0.1 0.029 14.6 0.0 1.4 1 1 0 1 1 1 0 MutS domain II Peptidase_M41 PF01434.18 EGO18566.1 - 7.9e-62 208.5 0.4 1.4e-61 207.7 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGO18566.1 - 1.7e-41 141.7 0.0 3.4e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO18566.1 - 2e-10 40.3 0.0 4.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGO18566.1 - 2.7e-05 24.0 0.0 0.00015 21.5 0.0 2.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO18566.1 - 7.4e-05 23.2 1.2 0.0031 17.9 1.2 2.9 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EGO18566.1 - 8.8e-05 21.9 0.1 0.00022 20.6 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EGO18566.1 - 0.0001 22.3 0.0 0.0004 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO18566.1 - 0.00036 20.8 0.3 0.0068 16.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO18566.1 - 0.0013 19.3 0.0 0.0039 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGO18566.1 - 0.0029 17.4 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGO18566.1 - 0.0034 16.8 0.4 0.0077 15.6 0.4 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGO18566.1 - 0.0043 16.7 0.7 0.25 10.9 0.4 2.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EGO18566.1 - 0.0058 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGO18566.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EGO18566.1 - 0.022 14.7 0.1 0.085 12.8 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EGO18566.1 - 0.023 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGO18566.1 - 0.028 14.9 0.4 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGO18566.1 - 0.039 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EGO18566.1 - 0.053 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGO18566.1 - 0.095 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGO18566.1 - 0.12 11.4 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EGO18566.1 - 0.2 11.1 0.1 0.72 9.3 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGO18566.1 - 0.2 10.9 0.6 0.54 9.5 0.6 1.6 1 0 0 1 1 1 0 Zeta toxin HBB PF06777.11 EGO18567.1 - 6.1e-42 143.4 1.3 6.8e-42 143.3 0.5 1.5 2 0 0 2 2 2 1 Helical and beta-bridge domain DEAD_2 PF06733.15 EGO18567.1 - 5.4e-17 62.0 0.2 1.1e-16 61.0 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 YtxC PF08812.11 EGO18567.1 - 0.075 12.6 0.3 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 YtxC-like family DUF2058 PF09831.9 EGO18567.1 - 0.079 13.1 0.2 0.16 12.1 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Meis_PKNOX_N PF16493.5 EGO18567.1 - 0.13 12.6 0.1 9.2 6.7 0.0 2.5 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 DEAD_2 PF06733.15 EGO18568.1 - 1.1e-18 67.4 1.1 1.3e-18 67.2 1.1 1.1 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EGO18568.1 - 0.059 13.4 0.0 0.066 13.2 0.0 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 EGO18568.1 - 0.084 13.6 0.6 0.24 12.1 0.2 1.8 1 1 1 2 2 2 0 CDH1/2 SANT-Helical linker 1 Cellulase PF00150.18 EGO18569.1 - 1.6e-16 60.6 1.8 6.4e-16 58.6 1.8 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EGO18569.1 - 0.00036 20.0 2.0 0.46 9.8 0.1 3.0 3 0 0 3 3 3 2 Beta-galactosidase Glyco_hydro_2_C PF02836.17 EGO18569.1 - 0.0071 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain TPR_12 PF13424.6 EGO18570.1 - 1.4e-06 28.5 3.2 0.2 12.0 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO18570.1 - 0.00018 21.3 1.2 2.4 8.1 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO18570.1 - 0.0042 17.1 4.5 0.56 10.5 0.0 4.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO18570.1 - 0.016 14.9 0.1 0.79 9.5 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 EGO18570.1 - 0.052 13.4 0.2 3.5 7.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGO18570.1 - 0.068 13.4 1.7 58 4.3 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGO18570.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Peptidase_M49 PF03571.15 EGO18571.1 - 1.1e-223 743.7 0.0 1.4e-223 743.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SpoIIE PF07228.12 EGO18572.1 - 1.3e-12 48.1 0.0 1.8e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGO18572.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C Abhydrolase_1 PF00561.20 EGO18573.1 - 2.7e-20 73.1 0.3 5.6e-19 68.8 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO18573.1 - 4.6e-15 56.8 0.0 6.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO18573.1 - 4.1e-11 42.6 0.1 4.9e-10 39.1 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EGO18573.1 - 0.001 17.8 0.0 0.087 11.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Ndr PF03096.14 EGO18573.1 - 0.083 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.11 EGO18573.1 - 0.15 11.0 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase F-box-like PF12937.7 EGO18574.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like XPA_C PF05181.12 EGO18574.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 XPA protein C-terminus F-box-like PF12937.7 EGO18575.1 - 0.00018 21.3 0.0 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like Glucan_synthase PF02364.15 EGO18577.1 - 0 1335.1 0.0 0 1334.5 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGO18577.1 - 9.2e-42 142.4 0.3 2.9e-41 140.8 0.3 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RAI16-like PF10257.9 EGO18578.1 - 1.7e-66 224.5 0.4 3e-66 223.7 0.4 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DnaJ PF00226.31 EGO18579.1 - 1.5e-19 69.8 1.5 1.5e-19 69.8 1.5 2.0 2 0 0 2 2 2 1 DnaJ domain Aldo_ket_red PF00248.21 EGO18580.1 - 1.2e-49 169.2 0.0 1.3e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PPK2 PF03976.14 EGO18580.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) DUF5134 PF17197.4 EGO18581.1 - 0.039 13.9 0.3 0.039 13.9 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) Rubis-subs-bind PF09273.11 EGO18582.1 - 0.07 13.8 0.0 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Peptidase_S32 PF05579.13 EGO18583.1 - 0.12 11.5 0.3 0.19 10.9 0.3 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Pico_P2A PF00947.19 EGO18583.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Picornavirus core protein 2A adh_short PF00106.25 EGO18584.1 - 4.2e-51 173.2 3.7 5.6e-51 172.8 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO18584.1 - 4.9e-34 117.9 2.7 6.4e-34 117.5 2.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO18584.1 - 1.1e-14 54.7 2.2 1.5e-14 54.4 2.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO18584.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGO18584.1 - 0.0033 16.9 0.5 0.005 16.3 0.5 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EGO18584.1 - 0.0064 16.2 1.1 0.018 14.8 1.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Utp12 PF04003.12 EGO18586.1 - 0.019 15.3 0.2 0.021 15.2 0.2 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family Abhydrolase_1 PF00561.20 EGO18587.1 - 4.9e-06 26.4 0.1 1.2e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO18587.1 - 0.00014 21.2 0.0 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ribosomal_S21 PF01165.20 EGO18589.1 - 1.1e-11 44.2 7.2 2.2e-11 43.3 7.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Cyclin_N PF00134.23 EGO18591.1 - 2.2e-14 53.3 0.1 4.5e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGO18591.1 - 4.5e-05 23.4 0.0 0.00041 20.3 0.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EGO18591.1 - 0.001 19.1 0.2 0.35 10.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin, C-terminal domain IF-2B PF01008.17 EGO18594.1 - 8.4e-60 202.4 0.0 2e-59 201.1 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4240 PF14024.6 EGO18594.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Peptidase_M24 PF00557.24 EGO18597.1 - 1.4e-50 171.9 0.1 1.7e-50 171.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGO18597.1 - 2.3e-15 56.6 5.1 4.1e-15 55.8 5.1 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Acyltransferase PF01553.21 EGO18598.1 - 1.3e-05 24.8 0.0 7.3e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase CLASP_N PF12348.8 EGO18599.1 - 4.2e-30 105.0 0.0 8e-10 38.7 0.0 5.5 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 EGO18599.1 - 1.5e-09 37.3 16.0 0.084 13.2 0.0 11.3 13 0 0 13 13 13 2 HEAT repeat Cnd1 PF12717.7 EGO18599.1 - 8.2e-09 35.7 0.1 1 9.4 0.0 6.4 6 0 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO18599.1 - 1.6e-07 31.6 13.6 0.43 11.0 0.0 9.2 6 3 4 10 10 10 2 HEAT repeats HEAT_EZ PF13513.6 EGO18599.1 - 0.00012 22.5 4.3 12 6.6 0.0 6.8 6 1 1 7 7 6 1 HEAT-like repeat TAN PF11640.8 EGO18599.1 - 0.0035 17.5 2.4 0.5 10.5 0.0 4.3 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 EGO18599.1 - 0.063 12.8 9.2 20 4.7 0.1 6.9 9 0 0 9 9 9 0 Dos2-interacting transcription regulator of RNA-Pol-II TPR_19 PF14559.6 EGO18599.1 - 0.094 13.2 0.3 20 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat VHS PF00790.19 EGO18599.1 - 0.1 12.4 0.1 25 4.7 0.0 3.8 4 0 0 4 4 4 0 VHS domain Nipped-B_C PF12830.7 EGO18599.1 - 0.14 12.1 0.0 18 5.2 0.0 3.0 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Lant_dehydr_C PF14028.6 EGO18599.1 - 0.39 10.2 3.1 0.4 10.2 0.1 2.5 3 0 0 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term NOC3p PF07540.11 EGO18600.1 - 7.8e-32 109.6 0.1 3e-31 107.7 0.1 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EGO18600.1 - 1.5e-18 67.4 2.7 2.9e-18 66.5 0.0 2.6 2 1 0 2 2 2 1 CBF/Mak21 family TEA PF01285.18 EGO18601.1 - 2.5e-17 62.7 0.8 3.9e-17 62.1 0.8 1.3 1 0 0 1 1 1 1 TEA/ATTS domain MSC PF09402.10 EGO18602.1 - 1.3e-94 317.4 0.0 1.7e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EGO18602.1 - 3e-12 46.0 0.0 5.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Pyr_redox_2 PF07992.14 EGO18603.1 - 1.3e-10 41.0 0.0 3.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 EGO18603.1 - 0.011 15.1 0.6 0.017 14.4 0.6 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Kelch_1 PF01344.25 EGO18603.1 - 0.035 13.7 1.5 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Kelch motif DAO PF01266.24 EGO18603.1 - 0.11 12.0 0.8 5.1 6.6 0.2 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO18605.1 - 3e-12 46.4 0.0 9.6e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 EGO18605.1 - 0.035 13.4 0.5 0.052 12.8 0.5 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Kelch_1 PF01344.25 EGO18605.1 - 0.072 12.7 3.1 1.2 8.8 0.2 2.4 2 0 0 2 2 2 0 Kelch motif NAD_binding_9 PF13454.6 EGO18605.1 - 0.12 12.4 0.0 22 5.0 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding TSC21 PF15217.6 EGO18606.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 TSC21 family Cu_bind_like PF02298.17 EGO18608.1 - 4e-06 26.7 0.3 8.8e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 EGO18608.1 - 0.00039 20.8 0.4 0.0012 19.3 0.4 1.8 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family MKLP1_Arf_bdg PF16540.5 EGO18609.1 - 0.084 12.9 0.1 0.084 12.9 0.1 1.2 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 DUF4477 PF14780.6 EGO18610.1 - 5.3e-06 26.2 0.1 0.12 11.9 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) Adaptin_N PF01602.20 EGO18611.1 - 5e-121 404.8 6.1 6.3e-121 404.5 6.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO18611.1 - 1.5e-56 190.9 2.3 1.1e-54 184.8 0.2 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO18611.1 - 2e-11 44.1 9.4 4e-06 27.1 0.3 5.6 3 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 EGO18611.1 - 1.8e-09 37.0 4.8 0.037 14.3 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 EGO18611.1 - 0.00013 21.9 0.9 1.1 9.5 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGO18611.1 - 0.014 15.5 1.4 12 6.1 0.2 3.7 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGO18611.1 - 0.018 15.5 0.2 29 5.3 0.0 4.7 6 0 0 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 EGO18611.1 - 0.072 12.6 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal OTU PF02338.19 EGO18612.1 - 3.6e-20 72.8 0.0 7.2e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGO18612.1 - 0.00019 21.0 0.0 0.039 13.4 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain NIL PF09383.10 EGO18612.1 - 0.19 11.6 0.0 0.57 10.1 0.0 1.7 1 0 0 1 1 1 0 NIL domain Aldo_ket_red PF00248.21 EGO18613.1 - 1.2e-46 159.3 0.0 1.4e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bromo_TP PF07524.13 EGO18613.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated DUF4502 PF14950.6 EGO18614.1 - 0.021 14.3 0.2 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) ECH_1 PF00378.20 EGO18615.1 - 2e-25 89.5 0.0 2.4e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO18615.1 - 2.3e-14 53.6 0.0 2.8e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Cupin_2 PF07883.11 EGO18616.1 - 3e-08 33.3 0.6 5.9e-08 32.3 0.6 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGO18616.1 - 0.00086 19.2 0.5 0.0022 17.9 0.1 1.8 2 1 1 3 3 3 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGO18616.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Cupin RRM_1 PF00076.22 EGO18620.1 - 3.8e-25 87.5 0.0 1.5e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 EGO18620.1 - 3.7e-19 67.3 0.0 0.00017 21.1 0.0 5.4 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 EGO18620.1 - 7.5e-05 22.5 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 EGO18620.1 - 0.15 11.6 0.0 0.88 9.0 0.0 1.9 2 0 0 2 2 2 0 RNA-recognition motif CoA_transf_3 PF02515.17 EGO18621.1 - 0.0085 15.3 0.1 0.0099 15.0 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III CLTH PF10607.9 EGO18622.1 - 1.8e-21 76.6 0.0 7.5e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGO18622.1 - 2.1e-07 30.8 0.1 4.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EGO18622.1 - 0.0041 16.5 0.1 0.0041 16.5 0.1 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EGO18622.1 - 0.008 16.5 0.3 0.016 15.5 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO18622.1 - 0.01 15.8 0.2 0.018 15.0 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 EGO18622.1 - 0.02 14.7 1.4 0.051 13.4 1.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit NUMOD3 PF07460.11 EGO18622.1 - 0.098 12.9 1.4 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Prok-RING_4 PF14447.6 EGO18622.1 - 0.14 12.1 0.3 0.31 10.9 0.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO18622.1 - 0.21 11.5 0.8 0.42 10.5 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pirin PF02678.16 EGO18623.1 - 5.4e-29 100.3 0.3 1e-28 99.5 0.3 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGO18623.1 - 1.3e-23 83.3 0.0 6e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGO18623.1 - 0.04 13.6 0.9 0.19 11.4 0.5 2.2 2 0 0 2 2 2 0 Cupin domain AA_permease PF00324.21 EGO18624.1 - 1.5e-120 403.1 41.0 1.8e-120 402.8 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO18624.1 - 2.7e-28 99.0 46.1 3.7e-28 98.5 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.23 EGO18625.1 - 4e-56 190.2 0.0 6.4e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EGO18625.1 - 2.9e-46 157.9 9.4 5e-46 157.2 9.4 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EGO18625.1 - 2.5e-16 60.0 0.0 5.2e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO18625.1 - 3.8e-07 30.3 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO18625.1 - 2.1e-05 23.8 0.0 2.1e-05 23.8 0.0 2.3 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 U1snRNP70_N PF12220.8 EGO18625.1 - 1.7 9.3 10.0 0.091 13.4 2.8 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal K_oxygenase PF13434.6 EGO18626.1 - 1e-93 314.2 0.0 1.3e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGO18626.1 - 2.1e-06 27.8 0.1 5.9e-05 23.1 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGO18626.1 - 0.00016 22.2 0.0 0.083 13.5 0.0 3.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO18626.1 - 0.00029 20.2 0.0 0.0024 17.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO18626.1 - 0.011 15.0 0.0 15 4.7 0.0 3.2 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Condensation PF00668.20 EGO18627.1 - 8.1e-89 298.4 0.0 7e-33 114.0 0.0 3.9 4 0 0 4 4 4 3 Condensation domain AMP-binding PF00501.28 EGO18627.1 - 2.6e-86 289.9 0.0 5e-86 288.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGO18627.1 - 1.6e-29 102.1 4.0 4e-09 36.7 0.1 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.13 EGO18627.1 - 0.0024 16.8 0.0 0.0074 15.2 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter PTEN_C2 PF10409.9 EGO18627.1 - 0.0031 17.3 0.1 0.33 10.7 0.1 2.4 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein WES_acyltransf PF03007.16 EGO18627.1 - 0.021 14.6 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AMP-binding_C PF13193.6 EGO18627.1 - 0.024 15.6 0.1 0.11 13.4 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain SH2_2 PF14633.6 EGO18628.1 - 5.7e-76 254.7 0.3 5.7e-76 254.7 0.3 1.9 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 EGO18628.1 - 1.2e-29 103.0 0.1 1.3e-15 57.5 0.1 2.8 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EGO18628.1 - 6.9e-29 100.3 0.0 1.4e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 EGO18628.1 - 4.1e-27 94.9 0.1 4.1e-27 94.9 0.1 2.5 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EGO18628.1 - 3.7e-20 72.3 30.9 3.7e-20 72.3 30.9 6.4 5 2 2 7 7 7 1 Acidic N-terminal SPT6 SH2 PF00017.24 EGO18628.1 - 2.5e-08 33.9 0.0 1.1e-05 25.4 0.0 2.8 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 EGO18628.1 - 6.5e-08 33.4 2.8 7.3e-07 30.0 2.8 2.8 1 1 0 1 1 1 1 HHH domain Tex_N PF09371.10 EGO18628.1 - 0.01 15.5 0.2 0.36 10.5 0.0 2.7 2 0 0 2 2 2 0 Tex-like protein N-terminal domain S1 PF00575.23 EGO18628.1 - 0.058 13.7 3.2 0.26 11.7 2.7 2.2 2 0 0 2 2 2 0 S1 RNA binding domain B12-binding PF02310.19 EGO18628.1 - 0.059 13.4 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain SRP54 PF00448.22 EGO18629.1 - 9.4e-72 240.8 0.6 1.7e-71 239.9 0.6 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGO18629.1 - 4.2e-30 104.3 0.6 4.2e-30 104.3 0.6 4.1 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EGO18629.1 - 1.1e-19 70.3 4.6 3e-19 69.0 4.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EGO18629.1 - 0.00039 20.6 0.0 0.0009 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGO18629.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EGO18629.1 - 0.013 15.9 0.1 0.013 15.9 0.1 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EGO18629.1 - 0.06 13.1 2.5 0.097 12.4 0.1 2.6 3 0 0 3 3 3 0 AAA domain HTH_ParB PF17762.1 EGO18629.1 - 0.15 11.9 1.7 3.1 7.7 0.3 2.7 2 0 0 2 2 2 0 HTH domain found in ParB protein DUF4795 PF16043.5 EGO18629.1 - 3.4 7.2 7.2 6.6 6.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) WD40 PF00400.32 EGO18630.1 - 3.7e-08 33.9 10.2 0.012 16.5 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO18630.1 - 0.016 15.5 0.1 0.81 10.0 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_25 PF13649.6 EGO18631.1 - 8.7e-06 26.4 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO18631.1 - 5.9e-05 23.0 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO18631.1 - 9.7e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGO18631.1 - 0.004 16.6 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EGO18631.1 - 0.0081 16.3 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EGO18631.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EGO18631.1 - 0.04 14.7 0.0 0.1 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 EGO18631.1 - 0.074 12.4 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EGO18631.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_11 PF08241.12 EGO18631.1 - 0.16 12.7 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EGO18631.1 - 0.24 10.7 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 EGO18631.1 - 0.25 11.1 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase SCAMP PF04144.13 EGO18632.1 - 8.5e-56 189.0 6.9 9.8e-56 188.8 6.9 1.0 1 0 0 1 1 1 1 SCAMP family PrgI PF12666.7 EGO18632.1 - 1 10.1 3.8 0.55 11.0 1.4 1.8 1 1 1 2 2 2 0 PrgI family protein MFS_1 PF07690.16 EGO18634.1 - 7.2e-37 127.1 30.8 2.8e-36 125.2 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5392 PF17370.2 EGO18634.1 - 0.15 12.2 0.3 0.56 10.3 0.1 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5392) DUF2157 PF09925.9 EGO18634.1 - 7.5 6.3 9.4 39 4.0 5.7 3.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Ribosomal_L30_N PF08079.12 EGO18635.1 - 1.3e-26 92.6 15.6 1.3e-26 92.6 15.6 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGO18635.1 - 1.6e-18 66.3 1.2 1.6e-18 66.3 1.2 2.2 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e PNTB PF02233.16 EGO18636.1 - 3.9e-175 583.2 24.9 3.9e-175 583.2 24.9 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGO18636.1 - 1.1e-67 227.5 0.1 1.1e-67 227.5 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGO18636.1 - 4.9e-45 153.2 0.4 1.5e-44 151.6 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGO18636.1 - 2.4e-31 108.0 4.0 2.4e-31 108.0 4.0 4.8 3 1 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EGO18636.1 - 0.00059 19.2 0.7 0.71 9.2 0.1 3.9 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGO18636.1 - 0.018 14.3 0.3 0.037 13.3 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 EGO18636.1 - 0.02 14.7 0.1 0.14 11.9 0.1 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 EGO18636.1 - 0.038 14.0 0.2 0.27 11.2 0.2 2.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GIDA PF01134.22 EGO18636.1 - 0.045 12.8 0.6 0.074 12.1 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADK PF00406.22 EGO18637.1 - 2.7e-10 40.5 0.0 3.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGO18637.1 - 1.9e-09 38.1 0.0 2.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO18637.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO18637.1 - 0.003 18.1 0.0 0.0041 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 EGO18637.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 EGO18637.1 - 0.055 12.7 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EGO18637.1 - 0.059 13.1 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGO18637.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 EGO18637.1 - 0.14 12.3 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGO18637.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Epimerase PF01370.21 EGO18638.1 - 1.1e-07 31.6 0.0 2.4e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO18638.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGO18638.1 - 0.00052 19.5 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO18638.1 - 0.00075 18.6 0.0 0.0096 14.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO18638.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 EGO18638.1 - 0.036 13.5 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 EGO18638.1 - 0.067 12.4 0.2 17 4.5 0.0 2.9 3 0 0 3 3 3 0 Male sterility protein NCE101 PF11654.8 EGO18639.1 - 6.4e-20 70.6 0.0 8.8e-20 70.1 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 NatB_MDM20 PF09797.9 EGO18640.1 - 1.9e-73 247.6 2.5 3.8e-73 246.6 2.3 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 EGO18640.1 - 4.4e-05 23.9 0.0 0.69 10.9 0.0 5.1 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO18640.1 - 0.19 12.3 0.2 1.3 9.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4473 PF14747.6 EGO18640.1 - 1.7 9.3 3.5 2.3 8.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Gaa1 PF04114.14 EGO18641.1 - 1.4e-106 357.5 3.9 2.3e-105 353.5 3.9 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF2334 PF10096.9 EGO18641.1 - 0.19 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) TMEM237 PF15383.6 EGO18641.1 - 0.25 10.4 1.6 0.33 10.0 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 237 DUF4149 PF13664.6 EGO18641.1 - 7.4 7.0 9.5 6.9 7.1 6.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Med16 PF11635.8 EGO18642.1 - 2.2e-06 25.9 0.2 2.9e-05 22.2 0.2 2.0 2 0 0 2 2 2 2 Mediator complex subunit 16 ATG_C PF09333.11 EGO18643.1 - 6.2e-37 125.8 0.1 2.1e-36 124.2 0.1 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EGO18643.1 - 2.5e-12 46.9 0.0 7.4e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EGO18643.1 - 6.5e-09 35.7 0.0 4.5e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 EGO18643.1 - 0.00027 20.8 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal RPA_C PF08784.11 EGO18644.1 - 1.8e-13 51.0 0.0 3.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGO18644.1 - 2.3e-08 33.9 0.1 4.3e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EGO18644.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti_2 PF13742.6 EGO18644.1 - 0.016 15.4 0.2 0.13 12.5 0.1 2.4 2 1 1 3 3 3 0 OB-fold nucleic acid binding domain MarR_2 PF12802.7 EGO18644.1 - 0.17 11.8 0.0 1.4 8.8 0.0 2.3 3 0 0 3 3 3 0 MarR family DUF4766 PF15973.5 EGO18644.1 - 1.7 9.2 11.1 1.7 9.3 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) Snf7 PF03357.21 EGO18645.1 - 3.5e-16 59.3 4.7 5.4e-16 58.7 4.7 1.2 1 0 0 1 1 1 1 Snf7 CdvA PF18822.1 EGO18645.1 - 0.069 13.0 7.9 0.16 11.8 7.9 1.7 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Syntaxin-6_N PF09177.11 EGO18645.1 - 9.9 6.8 7.8 5.4 7.6 1.1 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PQ-loop PF04193.14 EGO18646.1 - 2.3e-38 129.7 8.9 1.9e-18 65.9 4.6 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EGO18646.1 - 0.0017 18.3 1.1 0.0017 18.3 1.1 1.9 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF1378 PF07125.11 EGO18646.1 - 2.2 8.5 4.2 17 5.7 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1378) Ribosomal_S12 PF17487.2 EGO18646.1 - 2.3 9.0 6.8 10 6.9 1.5 2.4 2 0 0 2 2 2 0 Ribosomal protein S12 DHDPS PF00701.22 EGO18648.1 - 1.7e-28 99.2 0.0 1.1e-27 96.5 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family CLTH PF10607.9 EGO18650.1 - 3.4e-15 56.2 0.0 4.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGO18650.1 - 0.04 13.9 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 LisH DUF952 PF06108.12 EGO18651.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF952) Tudor_3 PF18115.1 EGO18652.1 - 1.5e-17 63.2 0.1 3.1e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EGO18652.1 - 2.7e-09 37.1 0.1 6e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) BRCT PF00533.26 EGO18652.1 - 8.2e-09 35.7 0.0 5.7e-06 26.6 0.0 3.1 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGO18652.1 - 1.5e-06 28.5 0.0 0.074 13.5 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Tudor_2 PF18104.1 EGO18652.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 EGO18652.1 - 0.00015 21.4 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 BRCT_3 PF18428.1 EGO18652.1 - 0.00025 21.1 0.0 0.042 13.9 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF1325 PF07039.11 EGO18652.1 - 0.00031 20.9 0.0 0.00079 19.5 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain PTCB-BRCT PF12738.7 EGO18652.1 - 0.0091 15.9 0.0 1.1 9.2 0.0 2.9 2 0 0 2 2 2 1 twin BRCT domain YajC PF02699.15 EGO18652.1 - 0.024 14.5 1.0 0.024 14.5 1.0 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit Agenet PF05641.12 EGO18652.1 - 0.027 14.9 0.1 0.28 11.7 0.0 2.5 2 0 0 2 2 2 0 Agenet domain 53-BP1_Tudor PF09038.10 EGO18652.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor OTU PF02338.19 EGO18654.1 - 0.00024 21.6 0.0 0.00037 21.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Exo_endo_phos PF03372.23 EGO18655.1 - 0.0015 18.1 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RLL PF10036.9 EGO18655.1 - 0.015 15.1 0.0 0.016 15.0 0.0 1.0 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein UCH PF00443.29 EGO18657.1 - 1.7e-27 96.5 2.6 3.9e-27 95.4 2.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO18657.1 - 8.1e-07 28.9 13.8 7.8e-05 22.4 0.0 4.0 3 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGO18657.1 - 1.7e-06 27.7 0.5 3.5e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 EGO18657.1 - 4.5e-06 27.2 0.1 0.0042 17.7 0.0 3.0 2 0 0 2 2 2 2 DUSP domain Cas_CXXC_CXXC PF09706.10 EGO18657.1 - 1.8 8.8 6.0 4.3 7.7 0.3 3.6 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) LUC7 PF03194.15 EGO18658.1 - 3.2e-68 230.1 1.4 3.2e-68 230.1 1.4 1.4 2 0 0 2 2 2 1 LUC7 N_terminus Ank_2 PF12796.7 EGO18659.1 - 7.6e-13 48.9 0.1 5.7e-06 26.8 0.0 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO18659.1 - 1.8e-09 37.9 0.3 3.4e-06 27.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO18659.1 - 8e-08 32.4 0.2 7.1e-05 23.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO18659.1 - 1.7e-07 31.0 0.0 0.021 15.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGO18659.1 - 0.0041 17.5 0.2 0.14 12.7 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeat BCS1_N PF08740.11 EGO18660.1 - 9.1e-49 166.0 1.0 1.3e-48 165.5 1.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGO18660.1 - 5.3e-20 72.2 0.0 1.3e-19 70.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO18660.1 - 0.00034 21.1 0.0 0.00081 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGO18660.1 - 0.0012 18.4 0.0 0.0065 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO18660.1 - 0.0038 17.4 0.0 0.0076 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO18660.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO18660.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGO18660.1 - 0.022 15.3 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO18660.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 EGO18660.1 - 0.037 13.9 0.0 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EGO18660.1 - 0.04 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO18660.1 - 0.04 14.2 0.1 0.15 12.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGO18660.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGO18660.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGO18660.1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Viral_helicase1 PF01443.18 EGO18660.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EGO18660.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGO18660.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 EGO18660.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 EGO18660.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EGO18660.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 EGO18660.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain WBS_methylT PF12589.8 EGO18661.1 - 1.1e-22 80.5 8.1 1.1e-22 80.5 8.1 1.8 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGO18661.1 - 7.6e-10 39.3 0.0 1.8e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO18661.1 - 3.6e-08 34.0 0.0 8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO18661.1 - 6e-05 23.7 0.0 0.00019 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO18661.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO18661.1 - 0.0004 20.2 0.0 0.00061 19.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EGO18661.1 - 0.0087 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.16 EGO18662.1 - 3.1e-37 127.5 0.0 4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component XAP5 PF04921.14 EGO18663.1 - 4.5e-88 295.3 7.4 4.5e-88 295.3 7.4 2.2 1 1 1 2 2 2 1 XAP5, circadian clock regulator RuBisCO_small PF00101.20 EGO18663.1 - 0.024 14.6 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Glypican PF01153.19 EGO18663.1 - 0.33 9.7 5.1 0.34 9.7 4.4 1.3 1 1 0 1 1 1 0 Glypican Mito_carr PF00153.27 EGO18664.1 - 9.6e-44 147.3 0.1 2e-14 53.3 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Rrn6 PF10214.9 EGO18664.1 - 3.1e-13 49.2 1.9 2.5e-07 29.6 0.6 2.6 3 0 0 3 3 3 2 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.22 EGO18665.1 - 8.9e-22 77.6 1.2 2e-20 73.1 0.5 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Exo_endo_phos PF03372.23 EGO18666.1 - 1e-07 31.7 0.0 4.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.20 EGO18667.1 - 2.3e-18 66.2 0.0 2.4e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mannosyl_trans PF05007.13 EGO18668.1 - 1.7e-65 221.5 10.1 2.3e-65 221.0 10.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGO18668.1 - 2.7e-09 36.6 6.5 4.9e-09 35.7 6.5 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U ALG3 PF05208.13 EGO18668.1 - 0.0026 17.2 1.3 0.21 11.0 1.0 2.4 2 0 0 2 2 2 2 ALG3 protein Arf PF00025.21 EGO18669.1 - 7.4e-68 227.4 0.0 8.3e-68 227.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGO18669.1 - 1.3e-11 44.3 0.0 3.3e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGO18669.1 - 4.4e-11 42.5 0.0 5.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGO18669.1 - 5e-08 33.2 0.0 1.2e-07 32.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGO18669.1 - 1.1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EGO18669.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGO18669.1 - 4.2e-05 23.0 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGO18669.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGO18670.1 - 2.5e-21 75.9 0.0 3.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGO18670.1 - 1.1e-12 47.7 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO18670.1 - 4.8e-06 26.1 0.0 6.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO18670.1 - 1.4e-05 25.2 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGO18670.1 - 0.00068 19.9 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGO18670.1 - 0.0028 18.1 0.2 0.0056 17.1 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGO18670.1 - 0.016 14.7 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 EGO18670.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EGO18670.1 - 0.035 13.6 0.0 0.071 12.6 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B TIP49 PF06068.13 EGO18670.1 - 0.04 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EGO18670.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGO18670.1 - 0.063 13.7 0.0 0.094 13.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGO18670.1 - 0.069 12.7 0.0 0.89 9.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EGO18670.1 - 0.085 12.9 0.0 3 7.9 0.0 2.2 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.20 EGO18670.1 - 0.24 10.5 0.0 2 7.5 0.0 2.2 1 1 0 1 1 1 0 G-protein alpha subunit FRG1 PF06229.12 EGO18671.1 - 4.2e-26 91.9 0.1 4.2e-26 91.9 0.1 1.7 2 0 0 2 2 2 1 FRG1-like domain DUF1754 PF08555.10 EGO18671.1 - 0.0002 22.1 4.8 0.24 12.2 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Fascin PF06268.13 EGO18671.1 - 0.0004 20.6 0.0 0.00065 19.9 0.0 1.4 1 0 0 1 1 1 1 Fascin domain BRF1 PF07741.13 EGO18671.1 - 0.71 10.2 7.6 5.9 7.3 3.7 2.5 2 1 0 2 2 2 0 Brf1-like TBP-binding domain ATP-synt_D PF01813.17 EGO18672.1 - 1e-71 240.9 3.3 1.2e-71 240.6 3.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 EGO18672.1 - 0.062 12.8 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) PASTA PF03793.19 EGO18672.1 - 0.14 12.0 0.1 0.45 10.4 0.1 1.9 1 0 0 1 1 1 0 PASTA domain Cpn60_TCP1 PF00118.24 EGO18673.1 - 8.9e-149 496.2 14.0 1e-148 496.1 14.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSL_N PF06350.12 EGO18673.1 - 0.045 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus UFD1 PF03152.14 EGO18674.1 - 3.4e-70 235.0 0.0 4.2e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EGO18674.1 - 0.037 13.8 0.1 0.3 10.9 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 NMT_C PF02799.15 EGO18675.1 - 2.6e-85 285.2 0.0 5.7e-85 284.1 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGO18675.1 - 1e-76 256.2 0.0 1.7e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EGO18675.1 - 1.1e-05 25.5 0.0 0.0003 20.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Sigma70_ner PF04546.13 EGO18676.1 - 0.011 15.7 3.9 0.012 15.5 3.9 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region UPF0239 PF06783.11 EGO18676.1 - 0.15 12.3 6.3 0.19 11.9 6.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) OGG_N PF07934.12 EGO18677.1 - 3.3e-31 107.9 0.1 6.2e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGO18677.1 - 2.1e-15 57.1 0.0 3.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGO18677.1 - 0.0017 18.1 0.1 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif P_C10 PF14974.6 EGO18677.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein C10 NPR2 PF06218.11 EGO18678.1 - 2e-100 336.6 8.7 4.7e-84 282.7 6.8 3.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 RTC PF01137.21 EGO18679.1 - 5.1e-58 195.9 0.0 6.4e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGO18679.1 - 2.1e-38 131.0 0.0 3.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain ThiF PF00899.21 EGO18680.1 - 3.4e-63 213.3 0.0 4.8e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGO18680.1 - 4.9e-30 103.5 0.1 7.5e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EGO18680.1 - 0.0076 16.3 0.3 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGO18680.1 - 0.048 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EGO18680.1 - 0.087 13.4 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 1-cysPrx_C PF10417.9 EGO18680.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin UBA_e1_thiolCys PF10585.9 EGO18680.1 - 0.14 12.0 0.3 7.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site PglD_N PF17836.1 EGO18680.1 - 0.14 12.8 0.2 0.39 11.4 0.2 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Ecm33 PF12454.8 EGO18680.1 - 0.44 10.7 2.6 0.98 9.6 2.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein DUF2039 PF10217.9 EGO18681.1 - 0.14 12.5 8.5 0.31 11.4 3.3 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) LEA_2 PF03168.13 EGO18682.1 - 3.3e-07 30.8 0.0 5.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.7 EGO18682.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF1356 PF07092.12 EGO18682.1 - 0.024 13.9 1.0 0.038 13.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DivIC PF04977.15 EGO18683.1 - 0.041 13.6 0.2 0.068 12.9 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 EGO18683.1 - 0.084 12.2 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC24 PF15669.5 EGO18683.1 - 7 6.5 10.5 0.066 13.1 0.7 2.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family Sde2_N_Ubi PF13019.6 EGO18684.1 - 1.2e-18 67.5 0.0 1.3e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DEAD PF00270.29 EGO18685.1 - 1.7e-08 34.5 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO18685.1 - 0.0017 18.7 0.0 0.0052 17.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO18685.1 - 0.0031 17.5 0.0 0.0083 16.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC_3 PF13917.6 EGO18690.1 - 4.1e-06 26.7 1.4 4.1e-06 26.7 1.4 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EGO18690.1 - 1.1e-05 25.3 5.1 1.7e-05 24.7 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO18690.1 - 0.035 13.6 0.6 0.069 12.7 0.6 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain JmjC PF02373.22 EGO18691.1 - 1.9e-11 44.4 1.2 2e-10 41.1 0.0 2.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase C1_2 PF03107.16 EGO18691.1 - 0.0014 18.9 0.7 0.0069 16.7 0.7 2.1 1 0 0 1 1 1 1 C1 domain zf-C5HC2 PF02928.16 EGO18691.1 - 0.046 14.1 3.0 0.26 11.7 3.0 2.4 1 0 0 1 1 1 0 C5HC2 zinc finger Lebercilin PF15619.6 EGO18692.1 - 0.0054 16.4 7.8 0.0063 16.2 7.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 EGO18692.1 - 0.018 14.9 3.1 0.22 11.4 1.1 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NPV_P10 PF05531.12 EGO18692.1 - 0.051 14.0 3.1 0.22 12.0 1.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 EGO18692.1 - 0.25 12.0 8.3 0.34 11.5 7.7 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 EGO18692.1 - 7.6 7.2 15.7 0.28 11.8 3.5 2.6 1 1 1 2 2 2 0 SlyX Pkinase PF00069.25 EGO18694.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGO18694.1 - 4e-07 29.2 0.0 5.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGO18694.1 - 2.6e-06 26.9 0.0 6e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FMO-like PF00743.19 EGO18695.1 - 4.8e-20 71.5 0.0 1.6e-18 66.4 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO18695.1 - 2.5e-10 40.1 0.0 7.6e-08 31.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO18695.1 - 1.2e-08 34.5 0.0 5.5e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGO18695.1 - 4.7e-08 32.6 0.0 0.0051 16.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO18695.1 - 1.1e-07 31.9 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO18695.1 - 1.1e-06 28.5 0.9 2.3e-05 24.1 0.3 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO18695.1 - 0.0023 17.1 1.6 0.12 11.4 0.7 2.2 1 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGO18695.1 - 0.019 14.2 1.4 0.029 13.6 0.2 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EGO18695.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.15 EGO18695.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.6 EGO18695.1 - 0.09 12.8 0.4 0.36 10.8 0.2 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 EGO18695.1 - 0.12 11.1 0.1 0.22 10.2 0.0 1.4 2 0 0 2 2 2 0 MCRA family Shikimate_DH PF01488.20 EGO18695.1 - 0.17 11.9 0.0 27 4.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EGO18695.1 - 0.27 10.3 0.6 5.2 6.0 0.7 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO18695.1 - 2.1 9.0 5.3 0.34 11.5 0.2 2.4 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase Vac_ImportDeg PF09783.9 EGO18696.1 - 4e-55 186.0 0.0 1.2e-54 184.5 0.0 1.7 1 1 0 1 1 1 1 Vacuolar import and degradation protein Ras PF00071.22 EGO18697.1 - 7.9e-50 168.6 0.0 9.4e-50 168.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO18697.1 - 5.5e-30 104.0 0.0 8.8e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO18697.1 - 4.3e-10 39.3 0.0 5.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO18697.1 - 0.0006 19.2 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGO18697.1 - 0.0012 18.1 1.7 0.53 9.4 0.1 2.5 2 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGO18697.1 - 0.0026 17.8 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGO18697.1 - 0.021 15.2 0.1 0.19 12.2 0.1 2.2 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 EGO18697.1 - 0.021 14.3 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EGO18697.1 - 0.026 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGO18697.1 - 0.029 14.3 0.1 5 7.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF5118 PF17162.4 EGO18697.1 - 0.036 13.9 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 EGO18697.1 - 0.05 13.3 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO18697.1 - 0.096 13.1 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EGO18697.1 - 0.099 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGO18697.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGO18697.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 STAS PF01740.21 EGO18697.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 STAS domain Septin PF00735.18 EGO18697.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Septin MFS_1 PF07690.16 EGO18698.1 - 1.3e-51 175.6 42.5 1.9e-51 175.1 41.5 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO18698.1 - 2e-16 59.6 17.2 2.1e-16 59.5 16.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO18698.1 - 2.4e-12 46.5 11.1 2.4e-12 46.5 11.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TMEM100 PF16311.5 EGO18698.1 - 4.4 6.9 7.0 1.7 8.2 3.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 100 Ig_J_chain PF15097.6 EGO18700.1 - 3.6 7.5 6.2 3.2 7.7 0.6 2.2 2 0 0 2 2 2 0 Immunoglobulin J chain DUF434 PF04256.12 EGO18714.1 - 0.026 14.2 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF434) DUF434 PF04256.12 EGO18718.1 - 0.026 14.2 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF434) zf-CCHC PF00098.23 EGO18721.1 - 1.4e-07 31.2 2.6 3.1e-07 30.2 2.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO18721.1 - 7.3e-06 26.2 1.0 2e-05 24.7 0.3 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO18721.1 - 0.0051 16.8 2.6 0.01 15.8 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle NYD-SP28_assoc PF14775.6 EGO18721.1 - 0.043 13.9 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain zf-CCHC_2 PF13696.6 EGO18721.1 - 0.048 13.5 1.1 0.079 12.8 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.16 EGO18722.1 - 2.3e-24 86.0 61.0 3.9e-16 58.9 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.19 EGO18726.1 - 2.2e-18 66.5 0.0 2.7e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO18726.1 - 0.0028 17.4 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease SL4P PF17618.2 EGO18726.1 - 0.021 14.8 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein ketoacyl-synt PF00109.26 EGO18727.1 - 1.8e-57 194.9 0.0 5.8e-57 193.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGO18727.1 - 7.5e-46 157.1 0.0 1.2e-45 156.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGO18727.1 - 1.1e-39 136.2 0.0 3.3e-36 124.9 0.0 3.2 3 0 0 3 3 3 2 KR domain Ketoacyl-synt_C PF02801.22 EGO18727.1 - 4.6e-29 100.8 0.0 1e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EGO18727.1 - 1.1e-26 93.5 0.0 1.8e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.6 EGO18727.1 - 3.7e-21 75.7 0.0 7e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGO18727.1 - 1.3e-11 45.0 0.0 4.1e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGO18727.1 - 1.2e-09 38.0 0.0 5.7e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO18727.1 - 2.7e-07 30.8 0.2 6.4e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EGO18727.1 - 6.2e-05 22.5 0.0 0.22 11.0 0.0 4.2 5 1 0 5 5 5 2 short chain dehydrogenase Thiolase_N PF00108.23 EGO18727.1 - 0.00019 20.9 0.1 0.00033 20.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGO18727.1 - 0.0068 16.2 1.0 0.016 15.0 0.1 2.1 2 0 0 2 2 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Amido_AtzD_TrzD PF09663.10 EGO18727.1 - 0.087 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Polysacc_synt_2 PF02719.15 EGO18727.1 - 0.21 10.7 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CNPase PF05881.12 EGO18730.1 - 0.13 11.8 0.8 0.16 11.5 0.8 1.1 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) H_PPase PF03030.16 EGO18731.1 - 0.024 13.3 2.7 0.12 11.0 0.0 2.0 1 1 1 2 2 2 0 Inorganic H+ pyrophosphatase gag_pre-integrs PF13976.6 EGO18733.1 - 3.4e-10 39.6 0.1 5.5e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Sec_GG PF07549.14 EGO18736.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Chromo PF00385.24 EGO18738.1 - 2.6e-08 33.6 0.2 4.4e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Intg_mem_TP0381 PF09529.10 EGO18739.1 - 0.0013 18.3 0.7 0.0016 18.0 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF2461 PF09365.10 EGO18740.1 - 3.9e-67 226.3 0.5 7.2e-66 222.1 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical protein (DUF2461) DUF3527 PF12043.8 EGO18740.1 - 0.96 8.9 5.8 0.61 9.6 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3527) LtuA PF17446.2 EGO18741.1 - 0.13 12.7 0.2 0.19 12.2 0.2 1.2 1 0 0 1 1 1 0 Late transcription unit A p450 PF00067.22 EGO18742.1 - 5.6e-51 173.7 0.0 7e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 EGO18743.1 - 7.5e-13 49.4 0.0 1.3e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO18743.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.28 EGO18746.1 - 2.1e-96 323.1 0.2 4.5e-96 322.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO18746.1 - 7.7e-26 90.9 0.2 3.3e-24 85.6 0.1 3.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGO18746.1 - 6.7e-14 51.5 1.6 2e-13 50.1 0.9 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Crp PF00325.20 EGO18746.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family MFS_1 PF07690.16 EGO18747.1 - 2.4e-40 138.6 52.6 2.4e-40 138.6 52.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO18747.1 - 1.6e-21 76.4 24.8 2.2e-21 75.9 24.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO18747.1 - 1.1e-12 47.6 11.0 1.1e-12 47.6 11.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Mpv17_PMP22 PF04117.12 EGO18747.1 - 0.35 11.1 6.6 3.4 8.0 0.0 4.0 4 0 0 4 4 4 0 Mpv17 / PMP22 family V-SNARE PF05008.15 EGO18748.1 - 5.2e-22 78.0 9.0 8.6e-22 77.3 4.3 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGO18748.1 - 1.4e-16 60.5 3.6 1.4e-16 60.5 3.6 2.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGO18748.1 - 0.00018 21.3 0.4 0.00018 21.3 0.4 1.9 2 1 0 2 2 2 1 Sec20 DUF241 PF03087.14 EGO18748.1 - 0.0087 15.9 1.4 0.09 12.6 0.1 2.1 2 0 0 2 2 2 1 Arabidopsis protein of unknown function YcgR PF07317.12 EGO18748.1 - 0.0093 15.8 0.1 0.085 12.7 0.1 2.1 2 0 0 2 2 2 1 Flagellar regulator YcgR CC2-LZ PF16516.5 EGO18748.1 - 0.027 14.8 2.6 2.6 8.5 1.3 2.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MlaD PF02470.20 EGO18748.1 - 0.033 14.5 0.2 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 MlaD protein SNARE PF05739.19 EGO18748.1 - 0.044 13.8 1.4 0.044 13.8 1.4 2.5 2 0 0 2 2 2 0 SNARE domain VWA_2 PF13519.6 EGO18748.1 - 0.049 14.3 0.6 0.13 12.9 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF745 PF05335.13 EGO18748.1 - 0.062 13.0 2.4 1.6 8.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fusion_gly PF00523.18 EGO18748.1 - 0.065 11.5 0.3 0.1 10.8 0.3 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 LMBR1 PF04791.16 EGO18748.1 - 0.11 11.4 0.4 0.14 11.0 0.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 EGO18748.1 - 0.29 10.7 7.2 1.6 8.2 7.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF3619 PF12279.8 EGO18748.1 - 0.68 10.3 4.4 0.34 11.2 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) Peroxin-3 PF04882.12 EGO18749.1 - 2e-84 284.3 0.5 5.5e-47 160.8 0.0 2.8 1 1 1 2 2 2 2 Peroxin-3 Thioesterase PF00975.20 EGO18753.1 - 3.5e-09 37.1 0.0 1.2e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Peripla_BP_6 PF13458.6 EGO18753.1 - 0.025 14.2 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein KR PF08659.10 EGO18754.1 - 2.2e-13 50.5 0.2 2.7e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 EGO18755.1 - 6.5e-39 134.0 0.1 1.8e-38 132.6 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGO18755.1 - 1.7e-15 57.1 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGO18755.1 - 3.3e-06 26.7 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGO18755.1 - 0.0015 18.3 1.0 0.0037 17.1 0.1 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RVP_2 PF08284.11 EGO18757.1 - 1.4e-06 28.1 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO18757.1 - 2.1e-05 25.0 0.0 3.2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO18757.1 - 0.00064 20.3 0.0 0.00086 19.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 EGO18757.1 - 0.076 12.8 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DKNYY PF13644.6 EGO18758.1 - 0.0019 19.0 0.7 0.0023 18.7 0.7 1.1 1 0 0 1 1 1 1 DKNYY family DUF4939 PF16297.5 EGO18758.1 - 0.037 13.9 0.1 0.038 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RVP_2 PF08284.11 EGO18759.1 - 9.1e-08 32.0 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO18759.1 - 3.1e-06 27.7 0.0 4.7e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO18759.1 - 4.5e-05 24.0 0.0 6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Pollen_Ole_e_I PF01190.17 EGO18759.1 - 0.053 13.9 0.1 2.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Pollen proteins Ole e I like Retrotran_gag_2 PF14223.6 EGO18762.1 - 4.2e-07 29.7 0.1 5.8e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3464 PF11947.8 EGO18763.1 - 0.0022 17.8 0.1 0.0031 17.3 0.1 1.2 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Retrotrans_gag PF03732.17 EGO18765.1 - 5.9e-07 29.7 1.9 7.4e-07 29.4 0.5 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO18765.1 - 3.1e-05 23.9 2.7 7.4e-05 22.6 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle RNA_pol_3_Rpc31 PF11705.8 EGO18766.1 - 1.1 9.5 8.4 1.9 8.7 8.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EGO18766.1 - 1.3 8.7 8.9 2.1 8.0 8.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Plavaka PF18759.1 EGO18768.1 - 3.7e-69 233.4 2.2 5.5e-45 154.0 0.2 2.2 1 1 1 2 2 2 2 Plavaka transposase MLVIN_C PF18697.1 EGO18769.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Retrotrans_gag PF03732.17 EGO18770.1 - 1e-07 32.1 0.4 1e-07 32.1 0.4 2.2 2 1 1 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 EGO18773.1 - 0.00013 22.4 0.0 0.00017 22.1 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO18773.1 - 0.00015 22.3 0.0 0.00017 22.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO18773.1 - 0.041 13.7 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Cyclin_N PF00134.23 EGO18777.1 - 3.5e-24 85.0 2.5 1e-20 73.8 0.1 2.8 2 1 1 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO18777.1 - 2e-16 60.2 0.1 1.4e-15 57.4 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Plavaka PF18759.1 EGO18778.1 - 2.5e-46 158.4 0.0 4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase MULE PF10551.9 EGO18779.1 - 0.03 14.7 0.2 0.083 13.3 0.1 1.8 1 1 1 2 2 2 0 MULE transposase domain Retrotrans_gag PF03732.17 EGO18780.1 - 0.01 16.1 0.2 0.024 14.9 0.2 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Peptidase_M60_C PF18630.1 EGO18780.1 - 0.088 12.9 0.0 18 5.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain rve PF00665.26 EGO18781.1 - 0.00017 21.8 0.0 0.0008 19.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO18781.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Asp_protease_2 PF13650.6 EGO18783.1 - 0.0011 19.5 0.0 0.0025 18.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO18783.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 EGO18783.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease ketoacyl-synt PF00109.26 EGO18788.1 - 1.9e-54 184.9 0.0 1.8e-52 178.5 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGO18788.1 - 1.6e-37 129.7 0.0 2.5e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGO18788.1 - 3.2e-34 118.4 0.0 7e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGO18788.1 - 6.4e-27 94.6 0.0 1.2e-21 77.2 0.0 2.4 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGO18788.1 - 1.3e-26 92.9 0.0 2.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGO18788.1 - 4.9e-12 46.3 0.0 1.5e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 EGO18788.1 - 1.3e-08 35.3 0.0 3.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Thiolase_N PF00108.23 EGO18788.1 - 3.8e-05 23.2 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EGO18788.1 - 4e-05 23.9 0.5 0.00016 22.0 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.25 EGO18788.1 - 0.1 12.0 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase SAP PF02037.27 EGO18789.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SAP domain TPK_catalytic PF04263.16 EGO18790.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain zf-CCHC PF00098.23 EGO18793.1 - 5.5e-08 32.5 3.3 1.3e-07 31.4 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO18793.1 - 1.1e-06 28.8 0.0 1.1e-06 28.8 0.0 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_6 PF15288.6 EGO18793.1 - 0.055 13.3 1.0 0.11 12.3 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO18793.1 - 0.14 11.9 0.9 0.27 11.0 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO18793.1 - 0.14 12.2 8.7 0.5 10.4 8.7 2.0 1 1 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGO18793.1 - 0.18 11.6 1.5 0.38 10.6 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle ROKNT PF08067.11 EGO18794.1 - 0.092 13.0 1.7 0.26 11.6 1.7 1.8 1 0 0 1 1 1 0 ROKNT (NUC014) domain KDZ PF18758.1 EGO18795.1 - 3.2e-61 206.8 0.4 4.1e-61 206.4 0.4 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CofC PF01983.16 EGO18796.1 - 0.055 12.7 0.4 0.077 12.2 0.4 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like Plavaka PF18759.1 EGO18797.1 - 6.7e-34 117.6 0.0 1.1e-26 93.9 0.0 2.3 1 1 1 2 2 2 2 Plavaka transposase zf-C2HC_2 PF13913.6 EGO18797.1 - 0.024 14.5 0.5 0.054 13.4 0.5 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Cyclin_N PF00134.23 EGO18798.1 - 9.2e-42 141.8 1.5 1.7e-41 140.9 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO18798.1 - 1.9e-16 60.3 0.0 4.6e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain MFS_1 PF07690.16 EGO18799.1 - 4.4e-06 25.9 27.8 9.4e-06 24.8 27.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily InaF-motif PF15018.6 EGO18799.1 - 0.05 13.5 4.2 1.5 8.8 0.4 2.8 2 0 0 2 2 2 0 TRP-interacting helix MFS_4 PF06779.14 EGO18799.1 - 0.053 12.8 7.3 0.062 12.6 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF1664 PF07889.12 EGO18799.1 - 0.064 13.3 1.2 0.12 12.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MFS_1_like PF12832.7 EGO18799.1 - 0.28 10.0 6.5 0.36 9.6 6.5 1.1 1 0 0 1 1 1 0 MFS_1 like family CAP_N PF01213.19 EGO18803.1 - 3.2 7.2 5.8 3.8 6.9 5.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NAD_binding_4 PF07993.12 EGO18805.1 - 1.7e-28 99.5 0.0 2.6e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO18805.1 - 2.4e-15 56.1 1.2 3.6e-09 35.7 1.2 3.7 2 1 1 3 3 3 2 AMP-binding enzyme Epimerase PF01370.21 EGO18805.1 - 1.2e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO18805.1 - 0.032 13.6 0.0 0.13 11.7 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EGO18805.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FHA PF00498.26 EGO18806.1 - 0.00013 22.2 0.0 0.00037 20.8 0.0 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGO18806.1 - 0.00026 21.2 0.0 0.00054 20.2 0.0 1.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain p450 PF00067.22 EGO18810.1 - 1.1e-29 103.5 0.0 1.6e-29 103.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 JMY PF15871.5 EGO18811.1 - 0.016 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein NAD_binding_4 PF07993.12 EGO18816.1 - 6.2e-29 100.9 0.0 9.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO18816.1 - 3.9e-27 94.9 0.0 2.4e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EGO18816.1 - 6.3e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO18816.1 - 0.00095 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase GH3 PF03321.13 EGO18816.1 - 0.01 14.7 0.0 0.025 13.4 0.0 1.6 2 0 0 2 2 2 0 GH3 auxin-responsive promoter zf-CCHC PF00098.23 EGO18818.1 - 0.00011 22.1 4.6 0.00025 21.0 4.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO18818.1 - 0.089 12.6 1.7 0.21 11.5 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle UPF0128 PF03673.13 EGO18818.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) zf-CCHC_3 PF13917.6 EGO18818.1 - 0.67 10.0 5.2 1.6 8.8 5.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Pkinase_fungal PF17667.1 EGO18820.1 - 7.2e-10 38.2 0.0 9.8e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LuxT_C PF18285.1 EGO18829.1 - 0.14 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain Transformer PF06495.11 EGO18832.1 - 0.16 12.1 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DtxR PF18357.1 EGO18834.1 - 0.099 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain Smim3 PF17307.2 EGO18835.1 - 0.76 9.3 5.5 0.95 9.0 0.1 2.3 2 1 0 2 2 2 0 Small integral membrane protein 3 DUF4939 PF16297.5 EGO18836.1 - 0.0024 17.7 0.9 0.0056 16.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 EGO18836.1 - 0.0076 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF3289 PF11692.8 EGO18836.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) gag-asp_proteas PF13975.6 EGO18837.1 - 2.9e-07 30.9 0.0 3.3e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO18837.1 - 2.8e-06 27.9 0.0 3.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO18837.1 - 4.8e-05 23.1 0.0 5.3e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Candida_ALS_N PF11766.8 EGO18837.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Pkinase_fungal PF17667.1 EGO18841.1 - 0.0019 17.0 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Plavaka PF18759.1 EGO18842.1 - 1.8e-20 73.4 0.0 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 EGO18842.1 - 0.017 15.6 0.3 0.048 14.1 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4085 PF13315.6 EGO18842.1 - 0.072 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) CTNNBL PF08216.11 EGO18845.1 - 0.94 9.7 7.2 0.65 10.2 1.2 2.3 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Uds1 PF15456.6 EGO18845.1 - 1.9 8.7 7.9 3 8.0 2.9 2.2 2 0 0 2 2 2 0 Up-regulated During Septation DUF4407 PF14362.6 EGO18845.1 - 7 5.9 13.2 30 3.8 11.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Sec_GG PF07549.14 EGO18849.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Helitron_like_N PF14214.6 EGO18851.1 - 8.3e-10 39.2 0.1 2.1e-09 37.9 0.1 1.6 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus ATG_C PF09333.11 EGO18852.1 - 0.023 15.0 1.0 0.048 14.0 0.1 2.0 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain FHA PF00498.26 EGO18855.1 - 4.4e-07 30.1 0.0 8.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO18855.1 - 0.0007 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Fungal_trans PF04082.18 EGO18857.1 - 3.1e-09 36.3 0.6 6.7e-09 35.2 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO18857.1 - 0.27 11.4 6.8 0.49 10.6 6.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L24e PF01246.20 EGO18859.1 - 4.6e-32 110.1 5.9 4.6e-32 110.1 5.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HAGH_C PF16123.5 EGO18859.1 - 0.031 14.8 1.0 0.054 14.0 0.6 1.6 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus PCP_red PF08369.10 EGO18859.1 - 0.081 13.2 0.1 0.081 13.2 0.1 2.4 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit zf-FCS PF06467.14 EGO18859.1 - 0.11 12.4 4.1 0.19 11.7 4.1 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Cpn60_TCP1 PF00118.24 EGO18860.1 - 3.9e-162 540.3 3.4 4.5e-162 540.1 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 EGO18860.1 - 0.0063 16.5 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF627) TPX2 PF06886.11 EGO18860.1 - 1.1 9.6 5.7 0.12 12.6 0.7 2.0 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF104 PF01954.16 EGO18861.1 - 0.087 13.3 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF104 Glyco_hydro_1 PF00232.18 EGO18862.1 - 4.9e-154 513.1 0.5 5.9e-154 512.8 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GFO_IDH_MocA PF01408.22 EGO18863.1 - 6e-12 46.5 0.1 1e-11 45.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO18863.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 EGO18863.1 - 0.043 14.1 0.0 0.4 10.9 0.0 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 EGO18863.1 - 0.12 13.0 0.1 0.85 10.3 0.1 2.2 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain SHOCT PF09851.9 EGO18864.1 - 0.024 14.3 0.9 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Short C-terminal domain Med3 PF11593.8 EGO18864.1 - 0.11 11.7 3.3 0.12 11.5 3.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_23 PF13489.6 EGO18865.1 - 6.2e-08 32.7 0.0 8.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO18865.1 - 1.7e-07 31.8 0.0 3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO18865.1 - 3.4e-07 30.8 0.0 6.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO18865.1 - 5e-05 24.0 0.0 8.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO18865.1 - 9.6e-05 21.8 0.0 0.00027 20.3 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGO18865.1 - 0.00039 20.2 0.0 0.00092 19.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain VIT PF08487.10 EGO18866.1 - 1.4e-30 105.8 0.0 2.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGO18866.1 - 1.1e-16 61.2 0.0 1.3e-15 57.7 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGO18866.1 - 1e-10 42.2 0.0 8.9e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGO18866.1 - 3.3e-08 34.1 0.1 2e-07 31.6 0.1 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGO18866.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EGO18866.1 - 0.0023 17.4 0.5 1.5 8.2 0.1 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein PSD2 PF07624.11 EGO18866.1 - 0.079 12.7 0.1 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Abhydrolase_6 PF12697.7 EGO18869.1 - 1.6e-07 32.2 0.0 1.9e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO18869.1 - 9.2e-06 25.5 0.1 2.1e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO18869.1 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGO18869.1 - 0.033 13.7 0.0 3.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family TPP_enzyme_N PF02776.18 EGO18869.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain OPT PF03169.15 EGO18870.1 - 1.5e-146 489.6 52.2 1.7e-146 489.4 52.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DMA PF03474.14 EGO18870.1 - 0.17 11.5 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 DMRTA motif DUF2512 PF10710.9 EGO18870.1 - 1 9.0 6.2 11 5.7 2.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) DUF4470 PF14737.6 EGO18873.1 - 1.3e-26 92.6 0.0 2.7e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGO18873.1 - 8.2e-10 38.6 14.7 2.1e-09 37.3 14.7 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO18873.1 - 0.09 13.1 8.6 0.23 11.8 8.6 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Zn_ribbon_17 PF17120.5 EGO18873.1 - 1.3 8.7 7.9 3.4 7.4 7.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HIT PF04438.16 EGO18873.1 - 1.7 8.5 9.4 4.2 7.3 9.4 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.19 EGO18878.1 - 1.6e-70 238.1 0.0 3.5e-69 233.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO18878.1 - 2.6e-18 66.6 0.0 5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EGO18878.1 - 6.5e-07 29.3 0.1 1.1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO18878.1 - 1.8e-05 24.1 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGO18878.1 - 2.9e-05 22.9 0.0 5.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO18878.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO18878.1 - 0.00065 19.0 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO18878.1 - 0.00068 19.1 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO18878.1 - 0.00072 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO18878.1 - 0.0012 18.0 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGO18878.1 - 0.0026 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO18878.1 - 0.015 15.2 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGO18878.1 - 0.017 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGO18878.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGO18878.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Omega-toxin PF06357.11 EGO18878.1 - 0.028 14.2 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Omega-atracotoxin Trp_halogenase PF04820.14 EGO18878.1 - 0.04 12.8 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Methyltransf_2 PF00891.18 EGO18879.1 - 2.5e-24 85.8 0.0 1.5e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGO18879.1 - 2.4e-05 23.9 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGO18879.1 - 7.4e-05 23.4 0.0 0.00033 21.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO18879.1 - 7.9e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO18879.1 - 0.0043 17.8 0.0 0.012 16.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO18879.1 - 0.0047 17.6 0.0 0.017 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO18879.1 - 0.0088 15.9 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 EGO18879.1 - 0.009 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Met_10 PF02475.16 EGO18879.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein MarR PF01047.22 EGO18879.1 - 0.1 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_16 PF10294.9 EGO18879.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Aldedh PF00171.22 EGO18880.1 - 3.3e-145 484.1 0.0 4e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO18880.1 - 0.054 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pox_TAA1 PF03295.14 EGO18880.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal SecY PF00344.20 EGO18881.1 - 4.1e-74 249.6 8.0 5.1e-74 249.3 8.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGO18881.1 - 3.6e-19 68.3 0.1 2.2e-18 65.8 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Prokineticin PF06607.11 EGO18881.1 - 0.32 11.3 2.1 16 5.9 0.4 3.5 3 1 1 4 4 4 0 Prokineticin DUF805 PF05656.14 EGO18881.1 - 0.89 10.0 5.1 0.57 10.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) UNC-93 PF05978.16 EGO18882.1 - 1.9e-14 53.7 7.2 6.5e-14 51.9 7.2 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGO18882.1 - 1.7e-13 50.3 33.5 3.2e-13 49.3 33.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Hyr1 PF15789.5 EGO18882.1 - 0.083 12.5 1.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 PI-PLC-X PF00388.19 EGO18883.1 - 3.9e-54 182.2 0.0 7.4e-54 181.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGO18883.1 - 1e-43 148.3 0.0 2.3e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGO18883.1 - 4.9e-08 33.2 0.0 3.4e-06 27.3 0.0 2.7 1 1 0 1 1 1 1 C2 domain Chlam_OMP6 PF03504.13 EGO18883.1 - 0.026 14.8 0.4 0.076 13.3 0.1 1.9 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 6 Lipase_GDSL PF00657.22 EGO18884.1 - 2.8e-05 24.2 0.3 8.7e-05 22.6 0.3 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGO18884.1 - 0.0076 16.7 6.2 0.011 16.1 6.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RL11D PF11088.8 EGO18884.1 - 0.14 12.5 1.0 0.29 11.4 0.2 1.9 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 Cellulase PF00150.18 EGO18885.1 - 1.9e-14 53.8 7.5 2.6e-14 53.3 7.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 EGO18886.1 - 2.2e-80 270.7 0.0 3.1e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF913 PF06025.12 EGO18888.1 - 1.4 7.8 3.9 2.7 6.9 3.9 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) OrsD PF12013.8 EGO18891.1 - 1.3e-06 28.8 1.5 1.5e-05 25.4 0.4 2.9 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 EGO18891.1 - 1.3e-06 28.3 0.0 8.2e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO18891.1 - 0.0093 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Plavaka PF18759.1 EGO18892.1 - 8.6e-09 35.1 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF1848 PF08902.11 EGO18893.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Pkinase PF00069.25 EGO18894.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGO18894.1 - 3.2e-05 23.6 0.0 5.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EGO18894.1 - 3.3e-05 23.3 0.1 6.4e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO18894.1 - 4.8e-05 23.4 0.0 7.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO18894.1 - 0.0087 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO18894.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_3_C PF01915.22 EGO18896.1 - 3.1e-46 157.9 0.1 4.6e-46 157.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO18896.1 - 7.4e-33 114.3 0.0 2.2e-32 112.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Retrotrans_gag PF03732.17 EGO18899.1 - 5e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO18899.1 - 8e-06 25.7 4.7 1.8e-05 24.6 4.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO18899.1 - 0.57 10.2 5.9 1.5 8.8 5.9 1.7 1 0 0 1 1 1 0 Zinc knuckle iPGM_N PF06415.13 EGO18900.1 - 8.2e-74 247.7 0.1 1.2e-73 247.2 0.1 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EGO18900.1 - 3.3e-70 236.3 0.0 2.5e-69 233.4 0.0 1.9 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EGO18900.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGO18900.1 - 0.0014 18.1 0.1 0.023 14.1 0.1 2.8 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 EGO18900.1 - 0.0034 16.4 0.5 0.0058 15.6 0.5 1.3 1 0 0 1 1 1 1 Alkaline phosphatase WD40 PF00400.32 EGO18901.1 - 6.9e-117 378.0 43.3 1.9e-09 38.0 0.1 13.5 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO18901.1 - 3.1e-61 203.7 6.5 1.6e-06 28.3 0.0 12.2 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO18901.1 - 2.5e-28 99.0 7.5 0.05 12.6 0.1 12.1 1 1 10 12 12 12 11 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO18901.1 - 5.2e-25 86.8 6.6 0.087 12.8 0.1 12.2 12 0 0 12 12 12 5 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGO18901.1 - 6.1e-16 58.9 0.2 0.0079 16.1 0.0 4.8 1 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Ret2_MD PF18528.1 EGO18901.1 - 4.3e-13 49.4 0.0 9.9 6.6 0.0 10.2 5 2 8 13 13 11 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Proteasome_A_N PF10584.9 EGO18901.1 - 4.9e-13 48.5 13.3 1.4 8.7 0.0 11.9 12 0 0 12 12 12 2 Proteasome subunit A N-terminal signature NACHT PF05729.12 EGO18901.1 - 4.5e-10 39.7 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.6 EGO18901.1 - 1.7e-09 37.4 11.4 0.041 13.2 0.1 7.4 2 1 4 7 7 7 3 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EGO18901.1 - 2.4e-08 33.6 0.3 5.8 6.2 0.0 7.3 6 3 0 9 9 9 2 WD40-like domain Nup160 PF11715.8 EGO18901.1 - 3.9e-07 29.1 11.9 6.8 5.2 0.0 9.0 3 3 5 10 10 10 1 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 EGO18901.1 - 9.7e-07 27.9 2.6 3.9 6.2 0.0 7.0 4 2 5 9 9 9 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Cytochrom_D1 PF02239.16 EGO18901.1 - 3.5e-06 25.8 1.7 0.43 9.1 0.1 5.0 1 1 5 6 6 6 1 Cytochrome D1 heme domain AAA_16 PF13191.6 EGO18901.1 - 0.00041 20.8 0.0 0.00094 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ChapFlgA PF13144.6 EGO18901.1 - 0.001 19.1 0.0 10 6.2 0.0 4.9 3 2 2 5 5 5 0 Chaperone for flagella basal body P-ring formation AAA_22 PF13401.6 EGO18901.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGO18901.1 - 0.0024 17.1 0.0 0.011 14.9 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain DUF5570 PF17731.1 EGO18901.1 - 0.0037 17.4 19.0 1.6 8.8 0.0 8.0 2 2 8 11 11 11 1 Family of unknown function (DUF5570) RNA_helicase PF00910.22 EGO18901.1 - 0.015 15.7 0.0 0.13 12.7 0.0 2.6 3 0 0 3 3 2 0 RNA helicase AAA PF00004.29 EGO18901.1 - 0.022 15.2 0.0 0.21 12.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF5122 PF17164.4 EGO18901.1 - 0.029 14.6 7.6 44 4.5 0.0 6.6 7 0 0 7 7 6 0 Domain of unknown function (DUF5122) beta-propeller Parvo_NS1 PF01057.17 EGO18901.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 EGO18901.1 - 0.057 12.6 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) p450 PF00067.22 EGO18903.1 - 2.8e-49 168.1 0.0 3.5e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M4_C PF02868.15 EGO18903.1 - 0.17 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Aldo_ket_red PF00248.21 EGO18905.1 - 2.4e-63 214.1 0.0 2.9e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EGO18906.1 - 7.9e-68 228.8 0.0 9.8e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adap_comp_sub PF00928.21 EGO18907.1 - 2.4e-21 76.3 0.0 3.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO18907.1 - 1.4e-08 34.8 0.1 2.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1464 PF07318.12 EGO18907.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Phytoreo_Pns PF05451.11 EGO18907.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 ubiquitin PF00240.23 EGO18909.1 - 9.4e-35 118.2 0.3 1e-34 118.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGO18909.1 - 6.7e-16 57.9 0.5 7.3e-16 57.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO18909.1 - 2e-05 24.9 0.1 8.3e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO18909.1 - 0.00098 19.4 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGO18909.1 - 0.0012 18.8 0.2 1.3 9.1 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO18909.1 - 0.0023 18.0 0.1 0.0055 16.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGO18909.1 - 0.022 14.7 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGO18909.1 - 0.025 15.1 0.0 0.028 15.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGO18909.1 - 0.038 13.8 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF3861 PF12977.7 EGO18909.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) GPI-anchored PF10342.9 EGO18911.1 - 1.1e-06 29.3 0.7 1.1e-06 29.3 0.7 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NUDE_C PF04880.13 EGO18911.1 - 5.4 7.4 9.3 8.4 6.8 9.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Mucin PF01456.17 EGO18911.1 - 7.8 6.5 29.4 0.26 11.3 16.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_M76 PF09768.9 EGO18912.1 - 4.6e-72 241.3 3.0 5.9e-72 241.0 3.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EGO18912.1 - 0.046 13.6 3.9 0.09 12.6 3.5 1.6 1 1 0 1 1 1 0 SprT-like family OmdA PF13376.6 EGO18913.1 - 0.016 15.2 1.0 0.017 15.1 1.0 1.2 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated BCNT PF07572.12 EGO18913.1 - 0.46 10.6 5.8 0.53 10.4 5.8 1.1 1 0 0 1 1 1 0 Bucentaur or craniofacial development ECH_1 PF00378.20 EGO18914.1 - 7.5e-43 146.6 0.1 1.2e-42 146.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO18914.1 - 7.2e-25 88.2 0.1 1.1e-24 87.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPX2 PF06886.11 EGO18916.1 - 1.2e-12 47.8 31.4 3.2e-12 46.5 23.1 2.3 2 0 0 2 2 2 2 Targeting protein for Xklp2 (TPX2) UPF0564 PF10595.9 EGO18916.1 - 0.0021 17.2 12.6 0.011 14.9 12.6 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 DUF1204 PF06721.11 EGO18916.1 - 0.0034 16.9 4.2 0.004 16.6 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1204) Pox_G5 PF04599.12 EGO18916.1 - 0.015 14.3 3.2 0.017 14.1 3.2 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein IFT20 PF14931.6 EGO18916.1 - 0.099 12.8 8.1 0.16 12.2 8.1 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 AAA_23 PF13476.6 EGO18916.1 - 0.7 10.3 8.2 0.76 10.2 8.2 1.1 1 0 0 1 1 1 0 AAA domain U1snRNP70_N PF12220.8 EGO18916.1 - 5.1 7.8 10.0 0.23 12.1 4.2 1.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NUDIX PF00293.28 EGO18920.1 - 1.6e-12 47.6 0.2 3.4e-12 46.5 0.2 1.6 1 1 0 1 1 1 1 NUDIX domain NIF3 PF01784.18 EGO18921.1 - 6.1e-54 183.2 0.0 7.4e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glutaredoxin PF00462.24 EGO18922.1 - 1.6e-16 60.2 0.0 2.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EGO18922.1 - 0.029 14.8 0.0 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain CSTF_C PF14304.6 EGO18923.1 - 8e-11 41.3 1.0 8e-11 41.3 1.0 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 EGO18923.1 - 1.3e-08 35.2 3.7 1.3e-08 35.2 3.7 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Spc7 PF08317.11 EGO18924.1 - 3.5e-28 98.4 11.6 4.5e-28 98.0 11.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EGO18924.1 - 3.2e-14 52.7 0.1 6.1e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 Filament PF00038.21 EGO18924.1 - 0.0004 20.1 10.0 0.00048 19.8 10.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein Atg14 PF10186.9 EGO18924.1 - 0.088 11.9 4.0 0.11 11.6 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1640 PF07798.11 EGO18924.1 - 0.12 12.4 6.0 0.2 11.7 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2120 PF09893.9 EGO18924.1 - 0.15 12.2 2.3 0.28 11.3 2.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) USP8_interact PF08941.10 EGO18924.1 - 0.29 10.9 3.4 0.4 10.5 2.4 1.7 1 1 1 2 2 2 0 USP8 interacting SlyX PF04102.12 EGO18924.1 - 0.45 11.2 4.6 1.8 9.2 2.5 2.8 2 1 1 3 3 3 0 SlyX HIP1_clath_bdg PF16515.5 EGO18924.1 - 0.52 11.0 13.2 0.9 10.2 9.1 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RasGAP_C PF03836.15 EGO18924.1 - 1.1 9.4 7.2 1.8 8.7 7.2 1.3 1 0 0 1 1 1 0 RasGAP C-terminus HAUS6_N PF14661.6 EGO18924.1 - 1.4 8.5 7.6 1.9 8.0 7.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fez1 PF06818.15 EGO18924.1 - 1.8 9.0 11.2 2.5 8.5 11.2 1.2 1 0 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 EGO18924.1 - 8.5 7.3 12.7 1.1 10.2 7.1 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF2203 PF09969.9 EGO18924.1 - 8.9 7.1 7.0 3.6 8.3 1.9 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Retrotrans_gag PF03732.17 EGO18925.1 - 1.6e-06 28.3 0.1 1.6e-06 28.3 0.1 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein RecX PF02631.16 EGO18925.1 - 0.055 13.9 2.2 0.086 13.3 1.6 1.6 1 1 0 1 1 1 0 RecX family Tetraspanin PF00335.20 EGO18926.1 - 1.7e-09 37.8 10.3 2.3e-09 37.3 10.3 1.2 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.14 EGO18926.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family DUF3278 PF11683.8 EGO18926.1 - 0.07 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Myb_DNA-bind_3 PF12776.7 EGO18929.1 - 6e-06 27.1 0.0 1.6e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO18929.1 - 0.00013 22.3 0.0 0.00091 19.6 0.0 2.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO18929.1 - 0.068 13.4 1.0 0.72 10.1 1.0 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain TT_ORF2 PF02957.15 EGO18929.1 - 0.075 14.0 1.0 0.19 12.6 1.0 1.7 1 0 0 1 1 1 0 TT viral ORF2 Retrotrans_gag PF03732.17 EGO18930.1 - 7e-05 23.0 2.9 0.055 13.7 0.0 2.7 1 1 2 3 3 3 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 EGO18930.1 - 0.00092 19.7 0.0 0.0032 18.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO18930.1 - 0.0023 18.5 0.0 0.0072 16.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF4939 PF16297.5 EGO18930.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RVP_2 PF08284.11 EGO18930.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease FlxA PF14282.6 EGO18930.1 - 0.19 11.7 0.6 0.36 10.8 0.6 1.4 1 0 0 1 1 1 0 FlxA-like protein DDE_3 PF13358.6 EGO18931.1 - 1.7e-07 31.1 0.0 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease TSGA13 PF14994.6 EGO18931.1 - 0.047 13.1 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Testis-specific gene 13 protein Chitin_synth_2 PF03142.15 EGO18932.1 - 2.8e-68 230.8 1.2 1.8e-66 224.9 0.8 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO18932.1 - 0.0049 16.8 0.1 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 TSC22 PF01166.18 EGO18932.1 - 0.1 12.9 0.5 0.21 11.9 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Plavaka PF18759.1 EGO18934.1 - 2.2e-37 129.0 0.1 7.9e-37 127.2 0.1 1.7 1 1 1 2 2 2 1 Plavaka transposase Ets PF00178.22 EGO18934.1 - 0.062 13.8 0.7 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Ets-domain SAS-6_N PF16531.5 EGO18934.1 - 0.42 11.2 1.7 14 6.3 0.8 3.2 2 1 0 2 2 2 0 Centriolar protein SAS N-terminal GntR PF00392.21 EGO18936.1 - 0.068 12.8 0.0 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Cohesin_load PF10345.9 EGO18936.1 - 0.18 10.2 10.9 0.96 7.8 4.2 2.5 2 1 0 2 2 2 0 Cohesin loading factor DIOX_N PF14226.6 EGO18938.1 - 5.2e-14 53.0 0.0 9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO18938.1 - 2.4e-13 50.4 0.0 4.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGO18939.1 - 1.3e-13 51.3 0.0 2.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGO18939.1 - 3.2e-11 44.0 0.0 5.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DIOX_N PF14226.6 EGO18940.1 - 4.1e-15 56.6 0.0 6.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO18940.1 - 2.1e-14 53.8 0.0 3.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DLH PF01738.18 EGO18942.1 - 2.7e-26 92.5 0.0 3.1e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGO18942.1 - 0.0041 16.6 0.0 0.024 14.1 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family ATG101 PF07855.12 EGO18943.1 - 9.5e-41 139.4 0.2 1.1e-40 139.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 ubiquitin PF00240.23 EGO18944.1 - 3.5e-13 49.1 0.7 7.1e-13 48.1 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGO18944.1 - 5.6e-11 42.1 0.1 1.6e-10 40.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGO18944.1 - 2.3e-05 24.1 0.7 4.1e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO18944.1 - 0.0014 19.2 0.2 0.0025 18.4 0.2 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain GerD PF17898.1 EGO18944.1 - 0.039 13.9 2.2 0.12 12.3 2.2 1.8 1 1 0 1 1 1 0 Spore germination GerD central core domain TBK1_ULD PF18396.1 EGO18944.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGO18944.1 - 0.16 12.1 0.7 0.57 10.3 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain RPN13_C PF16550.5 EGO18944.1 - 0.34 11.1 4.4 3.6 7.8 0.4 2.6 1 1 1 2 2 2 0 UCH-binding domain DLH PF01738.18 EGO18945.1 - 3.9e-24 85.4 0.2 4.5e-24 85.2 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGO18945.1 - 0.04 13.4 0.0 0.096 12.1 0.0 1.5 1 1 1 2 2 2 0 Prolyl oligopeptidase family Antimicrobial_1 PF08018.11 EGO18946.1 - 0.045 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide MPC PF03650.13 EGO18946.1 - 0.11 12.6 1.1 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers SNF2_N PF00176.23 EGO18947.1 - 2.1e-68 230.6 0.1 4.7e-68 229.5 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGO18947.1 - 9.3e-40 135.2 0.2 9.3e-40 135.2 0.2 3.9 4 1 1 5 5 5 1 SLIDE HAND PF09110.11 EGO18947.1 - 5.5e-31 107.6 3.8 5.5e-31 107.6 3.8 4.1 5 0 0 5 5 4 1 HAND Helicase_C PF00271.31 EGO18947.1 - 1.6e-18 67.1 0.1 1.1e-17 64.4 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO18947.1 - 7e-09 35.9 0.0 4.6e-08 33.3 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO18947.1 - 1.8e-07 30.7 0.1 5e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGO18947.1 - 6.7e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 EGO18947.1 - 0.00039 20.8 6.0 0.00039 20.8 6.0 5.0 5 0 0 5 5 5 2 DNA-binding domain Myb_DNA-binding PF00249.31 EGO18947.1 - 0.0013 18.8 0.2 0.42 10.8 0.0 3.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_14 PF13173.6 EGO18947.1 - 0.0022 18.0 0.1 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF1086 PF06461.11 EGO18947.1 - 0.026 14.4 0.1 0.098 12.5 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) EI24 PF07264.11 EGO18948.1 - 2.2e-09 37.8 4.8 3e-09 37.4 4.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Caa3_CtaG PF09678.10 EGO18948.1 - 0.023 14.2 0.7 0.054 12.9 0.2 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) AhpC-TSA_2 PF13911.6 EGO18949.1 - 2.2e-12 47.1 0.0 3.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGO18949.1 - 5.9e-09 35.9 0.0 7.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO18949.1 - 9.2e-08 31.9 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin Transp_cyt_pur PF02133.15 EGO18950.1 - 2.4e-25 89.2 30.7 3.6e-25 88.6 30.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Adaptin_N PF01602.20 EGO18951.1 - 1e-88 298.2 8.1 1.5e-88 297.7 8.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EGO18951.1 - 2.3e-60 202.2 0.0 6.8e-60 200.7 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EGO18951.1 - 5e-53 178.8 0.0 1.5e-52 177.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 EGO18951.1 - 2.4e-09 37.5 0.1 0.03 14.7 0.0 5.7 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 EGO18951.1 - 3.9e-07 29.8 2.1 0.23 11.8 0.0 5.5 5 0 0 5 5 4 2 HEAT repeat Cnd1 PF12717.7 EGO18951.1 - 1.3e-06 28.5 6.6 0.0025 17.9 0.1 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 EGO18951.1 - 5.7e-05 22.7 5.8 0.14 11.6 0.1 3.4 1 1 2 3 3 3 2 Family of unknown function (DUF5578) Coatomer_g_Cpla PF16381.5 EGO18951.1 - 0.00036 20.6 0.0 0.0016 18.5 0.0 2.2 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF5071 PF16804.5 EGO18951.1 - 0.0022 18.2 0.7 0.081 13.2 0.0 3.3 1 1 3 4 4 4 1 Domain of unknown function (DUF5071) ParcG PF10274.9 EGO18951.1 - 0.0036 17.4 0.9 0.33 11.1 0.0 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein RTP1_C1 PF10363.9 EGO18951.1 - 0.02 15.1 1.5 0.31 11.2 0.0 3.3 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EGO18951.1 - 0.036 14.4 1.4 21 5.6 0.0 4.0 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 EGO18951.1 - 0.079 12.4 3.4 0.34 10.3 3.1 2.1 2 1 0 2 2 2 0 Armadillo-like Meis_PKNOX_N PF16493.5 EGO18951.1 - 0.14 12.5 3.7 0.098 13.0 0.4 2.5 2 0 0 2 2 1 0 N-terminal of Homeobox Meis and PKNOX1 KDZ PF18758.1 EGO18953.1 - 5.3e-29 101.4 0.0 1.1e-28 100.3 0.0 1.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGO18953.1 - 0.0018 18.4 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-CCHC PF00098.23 EGO18955.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO18955.1 - 0.0078 16.0 0.5 0.012 15.4 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO18955.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain Nop10p PF04135.12 EGO18959.1 - 3.1e-21 75.2 1.6 3.5e-21 75.0 1.6 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CRAL_TRIO PF00650.20 EGO18960.1 - 2.1e-39 134.8 0.0 2.8e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO18960.1 - 8.8e-05 22.6 0.1 0.00017 21.7 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGO18960.1 - 0.00046 20.4 0.0 0.00067 19.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain IBV_3B PF03622.13 EGO18963.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 IBV 3B protein RRN3 PF05327.11 EGO18963.1 - 0.093 11.3 4.4 0.13 10.8 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SpoVAD PF07451.11 EGO18963.1 - 0.1 11.3 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) CDC45 PF02724.14 EGO18963.1 - 0.48 8.7 2.3 0.6 8.3 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Collagen PF01391.18 EGO18963.1 - 0.51 10.1 5.1 0.94 9.3 5.1 1.4 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Herpes_LMP1 PF05297.11 EGO18963.1 - 1.7 7.7 4.8 2.8 7.0 4.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-RING_2 PF13639.6 EGO18967.1 - 2.5e-06 27.7 7.7 2.5e-06 27.7 7.7 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGO18967.1 - 8.4e-06 25.6 8.6 8.4e-06 25.6 8.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO18967.1 - 0.00022 21.2 1.1 0.00022 21.2 1.1 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO18967.1 - 0.00044 20.2 6.5 0.00044 20.2 6.5 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGO18967.1 - 0.038 13.7 3.0 0.06 13.1 0.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger DivIC PF04977.15 EGO18967.1 - 0.057 13.2 2.5 0.13 12.0 2.5 1.5 1 0 0 1 1 1 0 Septum formation initiator HCMV_UL139 PF12507.8 EGO18967.1 - 0.064 13.6 0.3 0.064 13.6 0.3 1.9 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein HALZ PF02183.18 EGO18967.1 - 0.13 12.5 0.7 0.32 11.3 0.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper PAC3 PF10178.9 EGO18967.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 ZapB PF06005.12 EGO18967.1 - 0.89 10.0 14.8 0.057 13.9 6.4 2.6 3 0 0 3 3 2 0 Cell division protein ZapB Prok-RING_4 PF14447.6 EGO18967.1 - 1.1 9.2 15.9 0.045 13.6 6.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PRP1_N PF06424.12 EGO18968.1 - 0.29 11.5 3.8 0.5 10.8 3.8 1.6 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal ObR_Ig PF18589.1 EGO18969.1 - 0.13 12.6 0.2 0.16 12.4 0.2 1.1 1 0 0 1 1 1 0 Obesity receptor immunoglobulin like domain RHD3 PF05879.12 EGO18970.1 - 1.3e-08 33.5 0.1 1.3e-08 33.5 0.1 1.7 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EGO18970.1 - 5.3e-06 25.9 0.3 1e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain VWA_2 PF13519.6 EGO18972.1 - 5.4e-12 46.3 0.3 1.2e-11 45.2 0.3 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGO18972.1 - 0.0016 17.9 0.2 0.085 12.2 0.1 2.1 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA PF00092.28 EGO18972.1 - 0.002 18.4 0.8 0.057 13.7 0.8 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Enolase_C PF00113.22 EGO18973.1 - 1.1e-143 477.9 0.1 1.6e-143 477.4 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGO18973.1 - 2.6e-58 195.8 0.1 4.4e-58 195.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGO18973.1 - 2.7e-09 36.9 0.0 4.7e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGO18973.1 - 0.00039 19.7 0.3 0.00088 18.5 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus PAN_4 PF14295.6 EGO18974.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 EGO18974.1 - 0.042 14.0 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 PAN-like domain ADH_zinc_N PF00107.26 EGO18975.1 - 4.8e-12 46.0 0.3 9.6e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO18975.1 - 2e-05 24.4 2.0 0.0027 17.6 1.2 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO18975.1 - 0.014 16.4 0.0 0.032 15.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 EGO18976.1 - 4.5e-12 45.6 50.9 5.5e-08 32.1 31.5 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily NGP1NT PF08153.12 EGO18977.1 - 4.9e-50 169.0 0.0 1.2e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGO18977.1 - 1.7e-18 66.7 0.2 2.1e-14 53.5 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO18977.1 - 7.5e-06 25.6 0.2 7.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO18977.1 - 2.3e-05 24.4 0.0 7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EGO18977.1 - 0.00061 19.4 0.3 0.052 13.1 0.1 2.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Actino_peptide PF14408.6 EGO18977.1 - 0.008 16.3 0.2 0.026 14.6 0.2 1.8 1 0 0 1 1 1 1 Ribosomally synthesised peptide in actinomycetes Dynamin_N PF00350.23 EGO18977.1 - 0.014 15.5 0.7 5.1 7.1 0.1 3.6 2 1 1 3 3 3 0 Dynamin family Arf PF00025.21 EGO18977.1 - 0.019 14.4 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 EGO18977.1 - 0.092 13.0 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rhabdo_ncap PF00945.18 EGO18977.1 - 0.73 8.6 2.6 1.2 7.9 2.6 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Ribosomal_S15 PF00312.22 EGO18978.1 - 1.5e-26 92.4 0.4 3e-26 91.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S15 Sec34 PF04136.15 EGO18980.1 - 0.016 15.1 0.5 0.043 13.7 0.0 2.0 2 0 0 2 2 2 0 Sec34-like family RGCC PF15151.6 EGO18980.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family HetR_C PF18460.1 EGO18980.1 - 0.082 12.8 0.0 0.082 12.8 0.0 2.2 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain CAS_CSE1 PF03378.15 EGO18981.1 - 2.8e-05 22.8 0.1 0.00026 19.6 0.1 2.5 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGO18981.1 - 0.00011 22.1 0.0 0.0055 16.6 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain ParcG PF10274.9 EGO18981.1 - 0.00046 20.4 0.1 2.7 8.1 0.0 3.2 3 0 0 3 3 3 2 Parkin co-regulated protein HEAT_2 PF13646.6 EGO18981.1 - 0.0039 17.5 0.3 0.12 12.8 0.0 3.4 2 1 0 2 2 2 1 HEAT repeats Xpo1 PF08389.12 EGO18981.1 - 0.0042 17.2 0.2 0.029 14.4 0.0 2.7 2 1 0 2 2 2 1 Exportin 1-like protein Adaptin_N PF01602.20 EGO18981.1 - 0.0078 14.8 0.8 0.02 13.5 0.2 2.0 3 0 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 EGO18981.1 - 0.0091 16.0 0.0 0.09 12.8 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGO18981.1 - 0.016 15.5 2.7 0.21 11.9 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat CUTL PF16557.5 EGO18981.1 - 0.047 13.9 0.0 4.4 7.5 0.1 3.4 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB HEAT_EZ PF13513.6 EGO18981.1 - 0.19 12.3 5.3 66 4.2 0.0 6.0 7 0 0 7 7 7 0 HEAT-like repeat Plavaka PF18759.1 EGO18984.1 - 5.2e-34 117.9 0.0 2.1e-33 116.0 0.0 1.9 2 0 0 2 2 2 1 Plavaka transposase DUF3452 PF11934.8 EGO18984.1 - 0.016 14.7 0.1 0.04 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) zf-C2H2_4 PF13894.6 EGO18984.1 - 0.23 12.4 1.0 1.7 9.7 1.0 2.6 1 0 0 1 1 1 0 C2H2-type zinc finger FGF-BP1 PF06473.12 EGO18984.1 - 4.2 7.1 7.5 11 5.7 3.8 2.4 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Plavaka PF18759.1 EGO18986.1 - 4e-34 118.3 0.1 9.8e-34 117.0 0.1 1.6 1 0 0 1 1 1 1 Plavaka transposase TcdA_TcdB_pore PF12920.7 EGO18988.1 - 0.069 11.4 1.2 0.079 11.2 1.2 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Ribosomal_L29 PF00831.23 EGO18988.1 - 0.11 12.4 1.7 0.18 11.8 1.7 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein Med27 PF11571.8 EGO18992.1 - 0.049 14.0 0.2 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 27 PEP-utilisers_N PF05524.13 EGO18994.1 - 0.032 14.4 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Dioxygenase_N PF04444.14 EGO18994.1 - 0.081 12.8 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Retrotran_gag_2 PF14223.6 EGO18995.1 - 0.13 11.9 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NAD_binding_6 PF08030.12 EGO18998.1 - 1.2e-23 83.9 0.0 2.4e-23 83.0 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO18998.1 - 2.3e-22 79.1 0.0 5.6e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGO18998.1 - 2.7e-19 69.5 11.6 5e-19 68.6 11.6 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EGO18998.1 - 0.0047 17.5 0.0 0.11 13.1 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 EGO18998.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Ntox3 PF15536.6 EGO18998.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 Methyltransf_16 PF10294.9 EGO18999.1 - 3.3e-16 59.5 0.0 5.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGO18999.1 - 9e-06 26.4 0.0 1.7e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO18999.1 - 1.6e-05 25.5 0.0 6.4e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO18999.1 - 0.0003 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO18999.1 - 0.0029 17.4 0.0 0.0085 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGO18999.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGO18999.1 - 0.057 12.8 0.1 0.39 10.1 0.1 2.0 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_18 PF00704.28 EGO19000.1 - 2.6e-77 260.6 9.4 3.1e-77 260.4 9.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 EGO19000.1 - 0.042 13.8 0.3 0.16 11.9 0.2 1.7 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Homeodomain PF00046.29 EGO19002.1 - 1e-08 34.9 0.5 2e-08 34.0 0.5 1.5 1 0 0 1 1 1 1 Homeodomain gag_pre-integrs PF13976.6 EGO19004.1 - 5.4e-09 35.8 0.0 8.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Sec2p PF06428.11 EGO19005.1 - 0.031 14.2 0.2 0.034 14.1 0.2 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Ribosomal_L6e PF01159.19 EGO19008.1 - 0.29 11.7 2.4 0.49 10.9 2.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e Herpes_pp85 PF04637.12 EGO19008.1 - 0.55 8.6 5.0 0.5 8.7 2.8 1.8 1 1 1 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DDE_1 PF03184.19 EGO19009.1 - 2.5e-15 56.6 0.0 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO19009.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease p450 PF00067.22 EGO19010.1 - 5.8e-55 186.9 0.0 7e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EGO19011.1 - 1.9e-25 89.5 34.4 3.5e-25 88.7 34.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO19011.1 - 6.3e-08 31.5 1.1 6.3e-08 31.5 1.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 EGO19011.1 - 0.013 13.8 4.6 0.022 13.0 4.6 1.3 1 0 0 1 1 1 0 BT1 family DUF3847 PF12958.7 EGO19016.1 - 0.06 13.5 0.1 0.07 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) CBM_35 PF16990.5 EGO19017.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) MFS_1 PF07690.16 EGO19019.1 - 5.9e-28 97.8 32.3 9.1e-28 97.2 32.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO19019.1 - 4.1e-08 32.1 5.7 4.5e-08 32.0 1.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3817 PF12823.7 EGO19019.1 - 0.54 11.1 9.6 0.16 12.8 5.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) Lyase_aromatic PF00221.19 EGO19020.1 - 3.6e-137 457.8 1.7 4.6e-137 457.5 1.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Thioredoxin PF00085.20 EGO19021.1 - 1e-18 67.2 0.0 1.1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGO19021.1 - 0.0005 20.0 0.0 0.00056 19.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EGO19021.1 - 0.0038 17.7 0.1 0.04 14.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGO19021.1 - 0.0076 16.5 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EGO19021.1 - 0.044 14.0 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Mating_N PF12731.7 EGO19021.1 - 0.089 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein beta 1 Redoxin PF08534.10 EGO19021.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Redoxin E1_dh PF00676.20 EGO19022.1 - 0.0063 15.5 0.0 0.0063 15.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Adaptin_N PF01602.20 EGO19024.1 - 5.4e-113 378.3 7.4 7.5e-113 377.8 7.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO19024.1 - 7.5e-13 48.8 0.9 2.2e-08 34.3 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO19024.1 - 2e-06 28.1 2.9 0.22 11.9 0.2 4.9 4 1 1 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 EGO19024.1 - 2.4e-06 27.7 1.3 0.04 14.1 0.0 3.9 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EGO19024.1 - 0.00038 20.5 3.6 1.1 9.6 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Nipped-B_C PF12830.7 EGO19024.1 - 0.03 14.3 0.8 3.2 7.7 0.0 3.2 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 EGO19024.1 - 0.056 14.0 5.3 1.2 9.7 0.0 5.0 6 1 1 7 7 7 0 HEAT-like repeat FANCI_S1 PF14675.6 EGO19024.1 - 0.48 9.9 0.0 0.48 9.9 0.0 2.6 3 0 0 3 3 3 0 FANCI solenoid 1 DUF5578 PF17741.1 EGO19024.1 - 0.61 9.5 2.8 34 3.7 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Cation_efflux PF01545.21 EGO19027.1 - 6.6e-18 65.2 12.7 8.3e-18 64.8 12.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGO19027.1 - 1.2e-12 47.8 0.3 2.1e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FAP PF07174.11 EGO19029.1 - 6.2 6.2 17.7 5.5 6.4 16.2 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) F5_F8_type_C PF00754.25 EGO19033.1 - 0.00026 21.1 0.0 0.00031 20.9 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 EGO19033.1 - 0.041 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Y_phosphatase PF00102.27 EGO19034.1 - 8.7e-39 133.5 0.0 1.4e-21 77.2 0.0 3.0 3 0 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO19034.1 - 0.00017 21.8 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGO19034.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EGO19034.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ADH_zinc_N PF00107.26 EGO19035.1 - 3.2e-27 95.1 0.1 1.3e-26 93.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO19035.1 - 8.2e-17 62.5 0.1 2.1e-16 61.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO19035.1 - 1.3e-05 25.1 0.0 3.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EGO19035.1 - 0.016 15.5 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain PA PF02225.22 EGO19035.1 - 0.016 15.2 0.0 0.056 13.5 0.0 2.0 1 1 0 1 1 1 0 PA domain SIS_2 PF13580.6 EGO19035.1 - 0.044 13.8 1.5 0.066 13.2 0.3 1.9 2 0 0 2 2 2 0 SIS domain 2-Hacid_dh PF00389.30 EGO19035.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF2855 PF11017.8 EGO19035.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Cerato-platanin PF07249.12 EGO19040.1 - 0.089 12.9 1.2 2.4 8.3 0.1 2.2 1 1 1 2 2 2 0 Cerato-platanin HTH_psq PF05225.16 EGO19041.1 - 0.18 11.6 0.4 0.35 10.6 0.4 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Retrotrans_gag PF03732.17 EGO19042.1 - 2e-07 31.2 0.2 5.1e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO19042.1 - 2.9e-07 30.3 1.5 8.8e-07 28.7 1.5 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO19042.1 - 0.25 11.3 3.7 0.58 10.2 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 EGO19043.1 - 0.01 15.7 0.2 0.024 14.5 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGO19043.1 - 0.012 15.5 0.2 0.026 14.4 0.2 1.6 1 0 0 1 1 1 0 F-box domain CoA_binding_3 PF13727.6 EGO19043.1 - 0.054 13.5 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain tRNA-synt_His PF13393.6 EGO19048.1 - 1.3e-37 129.8 0.1 1.3e-32 113.3 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGO19048.1 - 9.8e-09 35.3 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGO19048.1 - 0.00044 20.3 0.0 0.0082 16.1 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 EGO19048.1 - 0.0032 17.6 5.0 0.0032 17.6 5.0 2.3 2 0 0 2 2 2 1 WHEP-TRS domain HHH_8 PF14716.6 EGO19048.1 - 0.11 12.8 3.1 0.38 11.2 0.0 3.1 3 1 1 4 4 4 0 Helix-hairpin-helix domain CDP-OH_P_transf PF01066.21 EGO19049.1 - 4.2e-18 65.9 0.1 4.2e-18 65.9 0.1 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Fungal_trans PF04082.18 EGO19050.1 - 1.1e-11 44.3 0.2 1.9e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EGO19051.1 - 6.7e-72 242.0 0.0 8.7e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19051.1 - 6.6e-39 133.8 0.0 9.3e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EGO19051.1 - 1.4e-17 64.2 0.9 4.6e-14 52.9 0.4 3.4 1 1 1 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EGO19051.1 - 1.2e-14 54.1 0.2 1.2e-14 54.1 0.2 2.1 3 0 0 3 3 3 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EGO19051.1 - 2.3e-06 27.1 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGO19051.1 - 0.00056 19.6 0.2 0.00095 18.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGO19051.1 - 0.0017 17.4 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO19051.1 - 0.027 14.4 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGO19051.1 - 0.045 13.1 0.6 0.19 11.1 0.6 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EGO19051.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Sec_GG PF07549.14 EGO19056.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Plavaka PF18759.1 EGO19057.1 - 9.1e-113 376.7 0.1 2.8e-61 207.6 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase BTB PF00651.31 EGO19057.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Se-cys_synth_N PF12390.8 EGO19057.1 - 0.19 12.0 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Retrotrans_gag PF03732.17 EGO19059.1 - 2.2e-07 31.0 0.5 2.2e-07 31.0 0.5 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO19059.1 - 1.3e-05 25.1 2.0 2.5e-05 24.1 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle FlxA PF14282.6 EGO19059.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.2 3 0 0 3 3 3 0 FlxA-like protein p450 PF00067.22 EGO19060.1 - 5.1e-75 253.0 0.0 6.4e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 EGO19061.1 - 1.4e-21 77.3 0.1 4.9e-21 75.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO19061.1 - 7.7e-12 46.3 0.5 1.1e-11 45.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO19061.1 - 1.4e-07 31.0 0.0 6.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGO19061.1 - 0.044 13.5 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 EGO19061.1 - 0.054 12.6 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 MFS_1 PF07690.16 EGO19062.1 - 2e-26 92.7 49.6 1.6e-14 53.6 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO19062.1 - 0.00025 19.8 25.0 0.00086 18.0 11.9 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein Peptidase_M17 PF00883.21 EGO19063.1 - 5.6e-119 397.0 0.0 7.7e-119 396.6 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EGO19063.1 - 0.00043 20.1 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain zf-FPG_IleRS PF06827.14 EGO19064.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS AlaDh_PNT_N PF05222.15 EGO19066.1 - 4.3e-27 95.1 0.0 6.4e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGO19066.1 - 7.4e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_28 PF00295.17 EGO19068.1 - 3.4e-36 124.9 1.5 4.8e-36 124.4 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EGO19068.1 - 0.0067 16.3 15.9 0.015 15.1 11.3 3.1 1 1 2 3 3 3 1 Right handed beta helix region Histone PF00125.24 EGO19069.1 - 1.5e-49 167.7 3.9 1.6e-49 167.6 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGO19069.1 - 2.6e-05 24.5 0.1 4.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGO19069.1 - 9.4e-05 22.5 1.2 0.0001 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGO19069.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 EGO19069.1 - 0.0024 18.4 2.2 0.0032 18.1 2.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 EGO19069.1 - 0.084 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EGO19069.1 - 0.12 12.5 0.4 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit EthD PF07110.11 EGO19071.1 - 3.5e-11 44.1 0.1 4e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EGO19071.1 - 0.0021 18.5 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Glucosamine_iso PF01182.20 EGO19072.1 - 4.4e-72 242.6 0.0 5e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase S6PP PF05116.13 EGO19073.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Ribosomal_L2_C PF03947.18 EGO19074.1 - 3.3e-54 182.4 0.5 6.3e-54 181.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGO19074.1 - 3.2e-25 87.9 0.2 6.2e-25 87.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TIP49 PF06068.13 EGO19075.1 - 1.2e-156 521.4 0.6 1.2e-156 521.4 0.6 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EGO19075.1 - 1.6e-21 76.2 1.5 1.3e-20 73.2 1.5 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EGO19075.1 - 3.7e-09 37.1 0.2 1.1e-05 25.9 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO19075.1 - 2.3e-06 27.5 0.3 0.0018 18.1 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EGO19075.1 - 4.3e-06 26.3 0.3 8.9e-06 25.2 0.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EGO19075.1 - 0.00012 22.5 0.2 0.00084 19.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO19075.1 - 0.0077 16.5 0.1 0.42 10.9 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGO19075.1 - 0.0094 15.5 0.2 0.033 13.8 0.1 1.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGO19075.1 - 0.011 15.1 3.3 0.17 11.2 0.3 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO19075.1 - 0.037 14.0 0.7 15 5.6 0.0 3.3 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 EGO19075.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_28 PF13521.6 EGO19075.1 - 0.079 13.2 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Prot_ATP_ID_OB PF16450.5 EGO19075.1 - 0.08 12.9 0.3 0.22 11.5 0.3 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain AAA_19 PF13245.6 EGO19075.1 - 0.12 12.7 3.8 0.37 11.1 0.9 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO19075.1 - 0.12 11.9 0.2 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3811 PF11656.8 EGO19077.1 - 1.6 9.2 5.0 2.2 8.7 0.4 3.0 3 0 0 3 3 3 0 YjbD family (DUF3811) Pheromone PF08015.11 EGO19077.1 - 9.4 7.4 11.3 7.6 7.7 0.0 3.7 4 1 0 4 4 4 0 Fungal mating-type pheromone DUF5045 PF16464.5 EGO19084.1 - 0.044 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) Thioredoxin PF00085.20 EGO19085.1 - 1.6e-28 98.7 0.0 1.8e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGO19085.1 - 9.4e-07 28.5 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGO19085.1 - 2e-06 27.7 0.0 2.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EGO19085.1 - 3.3e-06 27.5 0.1 1e-05 25.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EGO19085.1 - 8.3e-06 25.6 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGO19085.1 - 3.3e-05 24.1 0.1 8.1e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGO19085.1 - 0.0029 17.4 0.0 0.0033 17.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGO19085.1 - 0.0044 17.2 0.1 0.0062 16.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EGO19085.1 - 0.043 14.1 0.1 0.07 13.4 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin VASt PF16016.5 EGO19087.1 - 1.4e-38 132.7 0.1 2.3e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGO19087.1 - 0.02 14.7 0.0 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 GRAM domain Pkinase PF00069.25 EGO19088.1 - 1.8e-59 201.2 0.0 4.8e-35 121.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19088.1 - 2.9e-25 89.0 0.0 2.4e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGO19088.1 - 0.00039 21.1 9.9 0.00039 21.1 9.9 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain FTA2 PF13095.6 EGO19088.1 - 0.0071 16.0 0.1 0.86 9.2 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGO19088.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.24 EGO19088.1 - 0.025 14.6 0.0 0.11 12.5 0.0 2.1 1 1 0 1 1 1 0 PX domain APH PF01636.23 EGO19088.1 - 0.027 14.4 0.4 5.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO19088.1 - 0.19 11.0 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pyridox_oxase_2 PF12766.7 EGO19090.1 - 7.7e-25 87.4 0.1 1.6e-24 86.4 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EGO19090.1 - 2.3e-06 27.7 0.0 9.9e-06 25.7 0.0 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CorA PF01544.18 EGO19091.1 - 6.3e-35 120.9 7.3 1.2e-31 110.2 4.9 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein HAD_2 PF13419.6 EGO19092.1 - 1.6e-09 38.1 0.0 5.8e-09 36.3 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO19092.1 - 1.1e-06 29.1 0.2 2.2e-05 24.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO19092.1 - 1.9e-05 24.6 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ABC_tran PF00005.27 EGO19093.1 - 7.9e-48 162.4 0.0 2.6e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGO19093.1 - 6.2e-21 74.9 45.2 1.8e-10 40.4 8.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGO19093.1 - 1.1e-18 68.1 7.0 8.2e-06 25.8 0.0 4.9 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO19093.1 - 7.9e-07 29.8 1.7 0.029 14.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGO19093.1 - 2.1e-05 24.1 2.4 0.11 12.0 0.2 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO19093.1 - 9.2e-05 22.1 0.9 0.1 12.4 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_27 PF13514.6 EGO19093.1 - 0.0031 17.1 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGO19093.1 - 0.0034 17.3 0.2 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF4162 PF13732.6 EGO19093.1 - 0.012 16.3 0.0 0.57 10.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_30 PF13604.6 EGO19093.1 - 0.067 12.9 2.1 6.2 6.5 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_15 PF13175.6 EGO19093.1 - 0.15 11.7 0.0 20 4.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 EGO19093.1 - 0.42 10.2 2.4 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 EGO19093.1 - 3.3 7.1 52.2 0.055 12.9 21.3 4.9 4 1 0 4 4 4 0 ABC-2 type transporter Swi5 PF07061.11 EGO19094.1 - 1.3e-19 70.0 2.8 1.5e-19 69.9 2.8 1.0 1 0 0 1 1 1 1 Swi5 Band_3_cyto PF07565.13 EGO19094.1 - 0.0095 15.8 0.1 0.0096 15.7 0.1 1.0 1 0 0 1 1 1 1 Band 3 cytoplasmic domain RCC1 PF00415.18 EGO19095.1 - 5.8e-33 113.3 12.7 4.2e-07 30.5 0.8 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO19095.1 - 1.1e-10 41.0 29.3 0.005 16.6 0.6 7.9 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Raptor_N PF14538.6 EGO19096.1 - 3.8e-54 182.6 0.0 9.5e-54 181.3 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGO19096.1 - 3.9e-09 37.0 3.8 0.095 13.6 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 EGO19096.1 - 4.3e-05 23.4 0.7 0.00083 19.4 0.0 3.5 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGO19096.1 - 0.001 19.4 0.0 0.0051 17.2 0.0 2.2 1 0 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 EGO19096.1 - 0.0043 17.1 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 EGO19096.1 - 0.0046 17.2 0.0 16 5.9 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 EGO19096.1 - 0.035 14.6 0.0 0.22 12.1 0.0 2.4 2 0 0 2 2 2 0 HEAT-like repeat Pirin PF02678.16 EGO19096.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Pirin PfkB PF00294.24 EGO19097.1 - 3.9e-70 236.5 0.7 4.4e-70 236.4 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RdRP PF05183.12 EGO19098.1 - 3.5e-79 267.0 0.0 1.2e-78 265.2 0.0 1.8 1 1 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 EGO19099.1 - 1.9e-24 85.3 0.2 3.5e-13 49.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO19099.1 - 1.7e-11 43.8 0.0 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO19099.1 - 4.6e-07 29.6 0.0 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGO19099.1 - 0.012 15.6 0.3 0.24 11.5 0.1 2.8 2 1 0 2 2 2 0 Limkain b1 Malic_M PF03949.15 EGO19100.1 - 9.4e-84 280.7 0.0 1.3e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGO19100.1 - 1.2e-59 201.1 0.0 1.7e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ACP_PD PF04336.12 EGO19100.1 - 0.025 15.0 0.5 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase LysM PF01476.20 EGO19101.1 - 1.2e-13 50.8 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF4765 PF15962.5 EGO19101.1 - 0.12 10.3 0.4 0.15 10.0 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) TspO_MBR PF03073.15 EGO19102.1 - 3.6 7.6 18.9 0.072 13.2 9.5 2.0 1 1 1 2 2 2 0 TspO/MBR family HA2 PF04408.23 EGO19106.1 - 2e-18 66.7 0.0 5.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGO19106.1 - 7.8e-14 52.0 0.0 2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 EGO19106.1 - 6.5e-13 49.2 0.0 1e-07 32.5 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 EGO19106.1 - 1.1e-07 31.8 0.2 2.6e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EGO19106.1 - 8.8e-05 22.8 0.1 0.00021 21.6 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EGO19106.1 - 0.0037 17.6 0.1 0.0081 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO19106.1 - 0.19 12.0 0.3 0.82 9.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 EGO19107.1 - 3.6e-07 30.0 5.6 9.8e-07 28.6 5.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO19107.1 - 0.038 14.0 3.7 0.13 12.3 3.7 1.9 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO19107.1 - 0.063 13.6 1.5 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Ribosomal_L28e PF01778.17 EGO19108.1 - 9.4e-30 103.7 0.1 1.2e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family S4 PF01479.25 EGO19111.1 - 2.7e-12 46.2 0.5 2.7e-12 46.2 0.5 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EGO19111.1 - 5.2e-06 27.3 0.1 1.3e-05 26.0 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 EGO19112.1 - 6.4e-44 147.9 3.8 6.4e-44 147.9 3.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e zf-MYND PF01753.18 EGO19113.1 - 5e-08 32.9 10.3 9.3e-08 32.0 10.3 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO19113.1 - 0.052 13.9 12.1 0.27 11.6 12.1 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding COX5A PF02284.16 EGO19114.1 - 1.5e-42 143.8 0.1 1.8e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Polysacc_deac_1 PF01522.21 EGO19115.1 - 0.0018 18.2 0.1 0.0077 16.1 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase PRR18 PF15671.5 EGO19115.1 - 1.9 8.3 6.8 21 4.9 7.7 2.0 2 0 0 2 2 2 0 Proline-rich protein family 18 Acetyltransf_1 PF00583.25 EGO19117.1 - 2e-08 34.5 0.0 2.6e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO19117.1 - 3.3e-06 27.1 0.0 4.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO19117.1 - 1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO19117.1 - 0.00089 19.3 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGO19117.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 EGO19117.1 - 0.045 14.4 0.0 0.08 13.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGO19117.1 - 0.057 12.9 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase FMN_bind_2 PF04299.12 EGO19122.1 - 4.3e-54 182.7 0.0 5.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain p47_phox_C PF08944.11 EGO19125.1 - 0.012 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain gag-asp_proteas PF13975.6 EGO19126.1 - 5.5e-06 26.9 0.0 8.2e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO19126.1 - 1.7e-05 24.6 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO19126.1 - 0.00029 21.4 0.0 0.00034 21.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Pollen_Ole_e_I PF01190.17 EGO19126.1 - 0.028 14.8 0.1 3.1 8.3 0.0 2.0 1 1 1 2 2 2 0 Pollen proteins Ole e I like Asp_protease PF09668.10 EGO19126.1 - 0.16 11.8 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 EGO19127.1 - 0.013 15.5 0.9 0.021 14.9 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO19127.1 - 0.04 14.2 0.2 0.084 13.2 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 EGO19128.1 - 1.2e-07 32.0 0.4 1.2e-07 32.0 0.4 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO19128.1 - 5.6e-07 29.4 5.6 1.2e-06 28.4 5.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO19128.1 - 0.049 13.6 3.5 0.11 12.5 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3923 PF13061.6 EGO19129.1 - 0.066 13.3 0.7 0.066 13.3 0.7 3.8 6 0 0 6 6 6 0 Protein of unknown function (DUF3923) Chitin_synth_2 PF03142.15 EGO19131.1 - 6.1e-275 912.8 0.0 8e-275 912.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO19131.1 - 3.9e-10 40.0 0.4 1.3e-09 38.2 0.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO19131.1 - 5.5e-08 33.0 0.1 2.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGO19131.1 - 0.00089 18.8 0.1 0.036 13.6 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 BTB_2 PF02214.22 EGO19132.1 - 0.00079 19.7 0.0 0.0091 16.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain PTE PF02126.18 EGO19132.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotriesterase family SUI1 PF01253.22 EGO19133.1 - 1.2e-23 83.4 0.4 2.1e-23 82.6 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 EGO19133.1 - 0.054 13.5 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Herpes_teg_N PF04843.12 EGO19133.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Yae1_N PF09811.9 EGO19134.1 - 7.8e-10 38.3 5.2 1.3e-09 37.6 5.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cu_amine_oxid PF01179.20 EGO19135.1 - 2.1e-157 524.2 0.0 2.6e-157 524.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGO19135.1 - 8.2e-15 55.1 0.0 1.8e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EGO19135.1 - 4.5e-06 26.8 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Collagen PF01391.18 EGO19135.1 - 0.075 12.8 1.6 0.15 11.9 1.6 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF134 PF02001.16 EGO19135.1 - 0.1 13.1 0.0 7.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF134 DUF3140 PF11338.8 EGO19136.1 - 3.1e-24 85.2 1.2 3.1e-24 85.2 1.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) TPR_9 PF13371.6 EGO19137.1 - 0.0003 20.9 2.8 0.00047 20.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat NST1 PF13945.6 EGO19137.1 - 3.4 7.7 11.6 1.8 8.6 1.1 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator zf-C2H2 PF00096.26 EGO19139.1 - 2.8e-18 65.3 45.9 0.018 15.5 1.4 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO19139.1 - 1.1e-17 63.2 41.6 0.02 15.7 0.3 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO19139.1 - 2.6e-16 59.4 43.6 4e-05 23.8 2.4 7.9 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGO19139.1 - 1.2e-09 38.4 32.5 0.00099 19.4 13.0 5.4 1 1 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGO19139.1 - 3.6e-08 33.5 37.9 0.0055 17.1 3.2 7.2 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGO19139.1 - 1.8e-07 31.0 39.9 0.0001 22.2 0.9 7.7 6 1 1 7 7 7 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO19139.1 - 0.00027 21.2 40.3 0.3 11.6 0.2 8.2 8 0 0 8 8 8 3 Zinc-finger double domain DUF4187 PF13821.6 EGO19139.1 - 0.00054 19.7 27.8 0.013 15.2 1.7 5.9 2 1 4 6 6 6 2 Domain of unknown function (DUF4187) zf-C2HE PF16278.5 EGO19139.1 - 0.0033 17.8 1.7 0.16 12.5 0.2 5.9 3 1 4 7 7 7 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 EGO19139.1 - 0.0036 17.0 15.5 2.9 7.7 0.0 5.1 4 1 0 4 4 4 2 zinc-finger C2H2-type Zn_ribbon_2 PF12674.7 EGO19139.1 - 0.0047 17.6 13.7 0.026 15.2 0.6 3.4 4 0 0 4 4 3 2 Putative zinc ribbon domain zf-C2H2_9 PF16293.5 EGO19139.1 - 0.0082 16.0 20.6 9.6 6.1 0.0 6.9 4 1 3 7 7 7 0 C2H2 type zinc-finger (1 copy) ABM PF03992.16 EGO19139.1 - 0.22 11.7 1.6 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase CK_II_beta PF01214.18 EGO19139.1 - 0.43 10.4 16.4 5.1 6.9 0.1 4.2 2 1 2 4 4 4 0 Casein kinase II regulatory subunit zf_Hakai PF18408.1 EGO19139.1 - 0.69 9.7 7.1 0.19 11.4 1.2 3.1 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain DZR PF12773.7 EGO19139.1 - 3.5 7.7 23.6 3e+02 1.6 15.4 4.5 2 2 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EGO19139.1 - 3.6 7.1 16.7 8.4 6.0 0.4 6.1 6 0 0 6 6 6 0 zinc-ribbon domain AKAP95 PF04988.12 EGO19139.1 - 6 7.1 22.6 1.1 9.4 2.0 4.2 3 2 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf_C2H2_ZHX PF18387.1 EGO19139.1 - 6.6 6.5 36.2 1.4 8.6 2.0 5.9 2 2 4 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain EF-hand_1 PF00036.32 EGO19140.1 - 2.2e-27 92.5 17.1 2.4e-09 36.1 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO19140.1 - 3.7e-26 91.3 14.5 3.8e-13 49.7 5.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO19140.1 - 8.7e-23 78.3 12.1 2e-08 33.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGO19140.1 - 1.4e-14 53.6 15.7 6.6e-09 35.5 1.8 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGO19140.1 - 1.4e-11 44.6 2.3 2.6e-05 24.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGO19140.1 - 1.8e-11 43.0 7.2 0.0011 18.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EGO19140.1 - 3.1e-08 33.5 8.1 0.00087 19.2 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGO19140.1 - 0.00012 22.1 3.0 0.043 13.7 0.0 3.5 2 1 2 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGO19140.1 - 0.0063 16.8 3.5 0.53 10.6 0.2 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EGO19140.1 - 0.011 16.1 2.7 0.23 11.8 0.4 2.5 2 1 0 2 2 2 0 EF-hand domain DUF1636 PF07845.11 EGO19140.1 - 0.025 15.0 0.0 2.4 8.6 0.0 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1636) SurA_N_2 PF13623.6 EGO19140.1 - 0.087 12.7 0.9 3.7 7.4 0.4 2.5 2 1 0 2 2 2 0 SurA N-terminal domain DUF1059 PF06348.11 EGO19140.1 - 0.094 13.0 0.5 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-C2H2 PF00096.26 EGO19141.1 - 4.6e-10 39.4 7.7 2.7e-05 24.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO19141.1 - 2.5e-07 30.8 9.5 1e-06 28.9 3.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO19141.1 - 5.6e-06 26.8 11.8 0.00087 19.9 1.4 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGO19141.1 - 0.0013 19.0 0.5 0.0019 18.4 0.5 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 EGO19141.1 - 0.0021 18.6 0.9 1.2 9.8 0.1 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EGO19141.1 - 0.0091 16.2 3.5 0.87 9.7 0.6 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 EGO19141.1 - 0.02 14.9 1.0 0.02 14.9 1.0 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.12 EGO19141.1 - 0.045 14.5 3.1 2.2 9.1 0.4 2.2 1 1 1 2 2 2 0 CHORD zf-C2H2_3rep PF18868.1 EGO19141.1 - 0.078 13.7 0.7 0.85 10.3 0.1 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 EGO19141.1 - 0.15 12.4 1.6 23 5.4 0.2 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EGO19141.1 - 1.4 8.7 16.2 0.53 10.1 1.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 EGO19141.1 - 2.6 7.9 6.0 12 5.7 1.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type TauD PF02668.16 EGO19143.1 - 3e-45 155.1 0.1 3.9e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-TFIIIC PF12660.7 EGO19144.1 - 3.7e-22 78.2 0.9 3.7e-22 78.2 0.9 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 EGO19144.1 - 3.6e-20 72.7 8.3 9.9e-18 64.7 3.7 2.8 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term UPF0547 PF10571.9 EGO19144.1 - 0.28 11.3 2.2 25 5.1 0.0 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 WD40 PF00400.32 EGO19144.1 - 5.8 8.0 5.8 1.5e+02 3.5 0.2 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Glyco_hydro_47 PF01532.20 EGO19145.1 - 4.2e-147 490.7 0.0 5e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Trp_halogenase PF04820.14 EGO19147.1 - 2.7e-34 118.8 0.2 6.4e-17 61.5 0.2 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EGO19147.1 - 2.2e-16 60.1 0.0 4.4e-16 59.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGO19147.1 - 3.6e-07 29.9 0.0 8.5e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EGO19147.1 - 6.8e-07 29.2 0.1 0.0023 17.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO19147.1 - 3.8e-06 26.4 0.0 0.00011 21.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO19147.1 - 5.7e-06 26.8 0.0 0.025 15.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO19147.1 - 1.5e-05 23.9 0.0 3.7e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO19147.1 - 2.1e-05 24.7 0.0 7.1e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO19147.1 - 0.00031 20.0 0.1 0.001 18.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EGO19147.1 - 0.00045 19.4 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGO19147.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO19147.1 - 0.067 12.2 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein CTP_transf_3 PF02348.19 EGO19147.1 - 0.079 12.9 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase AlaDh_PNT_C PF01262.21 EGO19147.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ketoacyl-synt PF00109.26 EGO19148.1 - 1.8e-47 162.1 0.0 4.1e-47 160.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGO19148.1 - 1.5e-43 149.5 0.0 2.7e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGO19148.1 - 3.3e-32 111.9 0.0 1.8e-29 102.9 0.1 2.4 2 0 0 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 EGO19148.1 - 4.7e-27 94.4 0.0 1e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGO19148.1 - 3e-14 53.4 0.0 7.8e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension NAD_binding_4 PF07993.12 EGO19148.1 - 7.6e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.6 EGO19148.1 - 5.8e-11 42.2 0.0 1e-05 24.9 0.0 2.7 1 1 0 2 2 2 2 Polyketide synthase dehydratase PP-binding PF00550.25 EGO19148.1 - 0.011 16.0 0.2 0.026 14.9 0.2 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site Epimerase PF01370.21 EGO19148.1 - 0.056 12.9 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ACP_syn_III PF08545.10 EGO19148.1 - 0.062 13.2 3.4 0.048 13.5 0.5 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 EGO19149.1 - 2.5e-65 221.0 0.0 3.6e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YL1 PF05764.13 EGO19150.1 - 0.0069 16.5 14.4 0.0069 16.5 14.4 1.4 2 0 0 2 2 2 1 YL1 nuclear protein SR-25 PF10500.9 EGO19150.1 - 0.018 14.6 11.5 0.031 13.9 11.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGO19150.1 - 0.022 13.1 6.6 0.022 13.1 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Mit_KHE1 PF10173.9 EGO19150.1 - 0.14 12.3 1.6 0.28 11.2 1.6 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Cwf_Cwc_15 PF04889.12 EGO19150.1 - 0.82 9.3 17.3 1.6 8.4 17.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGO19150.1 - 2.4 6.1 15.6 3.7 5.5 15.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EGO19150.1 - 3.6 6.5 10.3 1 8.4 7.4 1.5 2 0 0 2 2 2 0 Pes-10 BUD22 PF09073.10 EGO19150.1 - 5.3 6.3 22.0 5 6.3 21.1 1.3 1 1 0 1 1 1 0 BUD22 MLVIN_C PF18697.1 EGO19152.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain COesterase PF00135.28 EGO19154.1 - 1.3e-72 245.3 0.0 2e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO19154.1 - 4e-08 33.4 0.0 1e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO19154.1 - 0.0027 17.2 0.1 0.0047 16.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SH3_9 PF14604.6 EGO19156.1 - 7e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO19156.1 - 3.4e-05 23.4 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO19156.1 - 0.039 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Fe-S_biosyn PF01521.20 EGO19157.1 - 1.7e-12 47.5 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis A_thal_3526 PF09713.10 EGO19160.1 - 0.13 12.6 0.1 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Peptidase_S10 PF00450.22 EGO19161.1 - 9.1e-110 367.9 0.1 1.1e-109 367.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GST_N_3 PF13417.6 EGO19163.1 - 1.1e-11 44.9 0.0 3.2e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO19163.1 - 3.3e-11 43.3 0.0 7.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGO19163.1 - 3.9e-06 27.1 0.0 4.4e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO19163.1 - 0.00042 20.3 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO19163.1 - 0.0055 16.9 0.0 0.0098 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO19163.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO19165.1 - 6.9e-12 45.6 0.0 1.4e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO19165.1 - 2.2e-08 34.3 0.0 3.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGO19165.1 - 0.0078 16.5 0.0 0.06 13.7 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribonuclease_3 PF00636.26 EGO19166.1 - 3.1e-41 140.2 0.0 7.2e-21 74.8 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EGO19166.1 - 4.1e-22 78.1 0.0 1.5e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EGO19166.1 - 1.4e-21 77.0 0.3 7.3e-09 35.9 0.0 4.8 5 0 0 5 5 5 4 Ribonuclease-III-like Helicase_C PF00271.31 EGO19166.1 - 1.9e-14 53.9 0.0 4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO19166.1 - 8.6e-14 51.7 0.0 1.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO19166.1 - 3.8e-11 43.3 0.0 8.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4242 PF14026.6 EGO19166.1 - 0.17 12.1 0.0 0.5 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) GST_N_3 PF13417.6 EGO19167.1 - 6.7e-12 45.7 0.0 1.6e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO19167.1 - 5.3e-11 42.7 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO19167.1 - 6.3e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO19167.1 - 0.0026 18.0 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO19167.1 - 0.048 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO19167.1 - 0.17 12.3 0.0 2.7 8.4 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_S10 PF00450.22 EGO19168.1 - 5.6e-26 91.9 0.0 6e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GFA PF04828.14 EGO19169.1 - 2.3e-06 27.8 0.6 3.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme MRF_C1 PF13887.6 EGO19172.1 - 0.067 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Pkinase PF00069.25 EGO19176.1 - 1.2e-06 28.1 0.0 6.5e-05 22.4 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19176.1 - 0.00063 19.1 0.0 0.0057 16.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGO19176.1 - 0.27 10.6 0.5 0.46 9.8 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Alpha_kinase PF02816.18 EGO19177.1 - 1.1e-07 32.1 0.0 1.4e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family LIM_bind PF01803.16 EGO19179.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein CSTF_C PF14304.6 EGO19181.1 - 0.00062 19.3 0.5 0.001 18.6 0.5 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Retrotrans_gag PF03732.17 EGO19181.1 - 0.027 14.7 1.5 0.23 11.8 1.5 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 EGO19182.1 - 2.6e-06 27.6 0.3 8.2e-06 26.0 0.0 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein Peptidase_C32 PF05411.12 EGO19182.1 - 0.0069 16.3 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus putative proteinase COesterase PF00135.28 EGO19184.1 - 1e-89 301.8 0.0 2.5e-88 297.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO19184.1 - 4.5e-05 23.4 0.2 0.00019 21.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO19184.1 - 0.00037 20.0 0.3 0.00073 19.1 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DAO PF01266.24 EGO19186.1 - 1.5e-51 176.1 0.1 2.7e-51 175.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EGO19186.1 - 5.3e-47 158.8 0.0 1.8e-45 153.9 0.1 2.4 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EGO19186.1 - 6.7e-07 28.7 1.0 0.0037 16.4 0.3 2.8 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EGO19186.1 - 5e-05 22.8 0.5 0.00027 20.4 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO19186.1 - 0.0055 16.0 0.1 0.032 13.5 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO19186.1 - 0.0076 15.5 0.1 0.017 14.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO19186.1 - 0.014 15.6 0.5 0.056 13.7 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO19186.1 - 0.091 13.3 0.2 0.23 12.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGO19186.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EGO19186.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO19186.1 - 0.16 10.7 0.6 0.23 10.1 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EGO19186.1 - 0.2 10.7 0.1 0.89 8.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A AMP-binding PF00501.28 EGO19187.1 - 2.4e-74 250.5 0.0 3e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO19187.1 - 2.5e-06 28.4 0.0 7.2e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 EGO19188.1 - 1.1e-09 37.9 2.8 0.00073 19.3 0.0 5.3 5 1 1 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 EGO19189.1 - 7.1e-41 139.8 0.0 9.3e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO19189.1 - 9.8e-30 103.8 0.0 1.2e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO19189.1 - 1.6e-08 34.7 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO19189.1 - 6.3e-05 22.6 0.1 0.00022 20.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO19189.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EGO19189.1 - 0.0091 16.2 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGO19189.1 - 0.013 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Na_H_Exchanger PF00999.21 EGO19191.1 - 1.5e-62 211.6 27.9 1.8e-62 211.3 27.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.20 EGO19191.1 - 0.25 11.0 1.2 0.71 9.6 1.2 1.7 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain NAD_binding_8 PF13450.6 EGO19192.1 - 1.4e-14 54.1 0.0 2.8e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGO19192.1 - 3e-13 49.9 0.0 7e-13 48.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGO19192.1 - 0.00058 19.5 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO19192.1 - 0.024 14.6 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGO19192.1 - 0.19 10.9 0.0 0.55 9.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EGO19193.1 - 9.1e-41 139.5 0.1 1.2e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO19193.1 - 1.1e-32 113.5 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO19193.1 - 9.5e-11 41.9 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO19193.1 - 3.3e-05 23.4 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EGO19193.1 - 0.0084 15.4 0.1 0.04 13.2 0.0 2.0 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phage_holin_4_1 PF05105.12 EGO19195.1 - 0.0059 16.7 0.3 0.0074 16.4 0.3 1.1 1 0 0 1 1 1 1 Bacteriophage holin family p450 PF00067.22 EGO19197.1 - 6.9e-35 120.7 0.0 9e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_35 PF01301.19 EGO19198.1 - 7.8e-72 242.6 0.1 1.2e-71 242.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EGO19198.1 - 1.1e-53 180.7 7.3 1.6e-32 112.4 0.1 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EGO19198.1 - 1e-38 133.0 2.5 2.5e-38 131.7 2.6 1.7 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EGO19198.1 - 2.1e-21 75.2 2.3 3.9e-21 74.4 0.4 2.5 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 XPG_N PF00752.17 EGO19200.1 - 5.3e-33 113.5 0.0 1.1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGO19200.1 - 1.2e-27 96.1 0.0 3.1e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EGO19200.1 - 0.00047 20.7 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Hap4_Hap_bind PF10297.9 EGO19201.1 - 4.9e-09 36.0 3.6 1.3e-08 34.7 3.6 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EGO19201.1 - 3.5e-05 23.8 20.1 0.0012 18.9 12.8 2.4 1 1 1 2 2 2 2 bZIP transcription factor HAUS-augmin3 PF14932.6 EGO19201.1 - 0.011 15.3 4.2 0.019 14.5 4.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_2 PF07716.15 EGO19201.1 - 0.025 14.6 19.8 0.89 9.7 7.9 2.9 1 1 1 2 2 2 0 Basic region leucine zipper Exonuc_VII_L PF02601.15 EGO19201.1 - 0.096 12.2 2.5 0.15 11.6 2.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Myc-LZ PF02344.15 EGO19201.1 - 0.35 11.0 5.9 0.72 10.0 5.9 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain TMF_DNA_bd PF12329.8 EGO19201.1 - 0.81 9.7 11.3 1.6 8.8 11.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EGO19201.1 - 1.1 9.7 12.8 1.8 9.0 12.0 1.7 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 EGO19201.1 - 1.3 9.7 5.1 3.1 8.5 5.1 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Ax_dynein_light PF10211.9 EGO19201.1 - 1.8 8.4 10.2 18 5.2 8.8 2.4 2 1 0 2 2 2 0 Axonemal dynein light chain Unstab_antitox PF09720.10 EGO19201.1 - 1.9 8.6 5.8 1.9 8.6 0.6 2.6 2 0 0 2 2 2 0 Putative addiction module component bZIP_Maf PF03131.17 EGO19201.1 - 8.9 6.9 15.2 17 6.0 3.0 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor Pex24p PF06398.11 EGO19202.1 - 1.1e-23 83.9 3.2 1.7e-23 83.3 3.2 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin AMP-binding PF00501.28 EGO19207.1 - 1.7e-17 63.1 0.0 2e-11 43.1 0.1 2.9 2 1 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 EGO19207.1 - 0.00037 19.5 0.3 0.0016 17.4 0.1 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter HNF-1A_C PF04813.12 EGO19207.1 - 0.12 13.2 1.3 0.8 10.5 1.3 2.3 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Trp_DMAT PF11991.8 EGO19208.1 - 1.4e-68 232.0 0.0 2e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Mso1_Sec1_bdg PF14475.6 EGO19208.1 - 0.092 12.4 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Thioredoxin_3 PF13192.6 EGO19211.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain NAD_binding_10 PF13460.6 EGO19212.1 - 2.1e-09 37.6 0.3 3.9e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO19212.1 - 1e-07 31.7 0.0 1.2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO19212.1 - 0.00015 21.4 0.2 0.00026 20.6 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EGO19212.1 - 0.00095 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 EGO19212.1 - 0.0019 18.4 0.1 0.0048 17.1 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 EGO19212.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGO19212.1 - 0.012 14.7 0.0 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 EGO19212.1 - 0.018 15.0 0.5 0.14 12.1 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EGO19212.1 - 0.032 13.5 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EGO19212.1 - 0.072 12.5 0.0 0.25 10.7 0.0 1.9 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Rossmann-like PF10727.9 EGO19212.1 - 0.089 12.7 0.3 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.18 EGO19212.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 EGO19212.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGO19212.1 - 0.19 11.4 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ketoacyl-synt PF00109.26 EGO19213.1 - 2e-79 266.8 0.0 3.2e-79 266.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGO19213.1 - 2.4e-41 142.3 0.0 6.9e-41 140.8 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGO19213.1 - 8.1e-37 125.9 0.2 1.6e-36 124.9 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 EGO19213.1 - 8.3e-22 78.1 3.1 1.7e-21 77.1 0.1 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 EGO19213.1 - 2.4e-21 76.3 0.0 4.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 EGO19213.1 - 4.2e-19 69.6 0.1 8.2e-17 62.1 0.0 3.1 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 EGO19213.1 - 3.2e-10 40.2 0.1 7.4e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGO19213.1 - 4.4e-08 33.6 0.0 1.2e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EGO19213.1 - 1.2e-07 32.5 4.1 2.2e-06 28.5 1.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 EGO19213.1 - 0.00036 20.0 0.2 0.00067 19.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.8 EGO19213.1 - 0.0018 17.9 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EGO19213.1 - 0.039 13.8 0.2 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold tRNA_synt_1c_R2 PF04557.15 EGO19214.1 - 0.48 11.4 3.5 1 10.3 3.5 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PhoH PF02562.16 EGO19215.1 - 0.093 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Kinesin PF00225.23 EGO19218.1 - 1.5e-93 313.4 0.0 2.8e-93 312.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO19218.1 - 1.2e-22 80.5 0.0 2.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 EGO19218.1 - 0.015 15.1 1.9 0.069 13.0 1.9 2.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Vfa1 PF08432.10 EGO19218.1 - 9.1 6.6 11.3 0.54 10.6 3.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.13 EGO19223.1 - 0.0016 18.6 5.8 0.0022 18.2 5.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF4011 PF13195.6 EGO19223.1 - 0.27 11.1 4.2 0.78 9.6 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) CDC45 PF02724.14 EGO19223.1 - 1.1 7.5 7.2 1.5 7.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein COesterase PF00135.28 EGO19225.1 - 2.6e-70 237.8 0.0 6.8e-69 233.1 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO19225.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2235 PF09994.9 EGO19226.1 - 5.2e-93 311.5 0.2 6.7e-93 311.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3473 PF11959.8 EGO19226.1 - 0.18 11.8 0.4 0.36 10.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Hist_deacetyl PF00850.19 EGO19227.1 - 8.1e-53 179.9 0.3 1.3e-52 179.2 0.3 1.4 1 0 0 1 1 1 1 Histone deacetylase domain PMI_typeI PF01238.21 EGO19228.1 - 2.3e-85 287.0 0.0 2.7e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EGO19228.1 - 7.6e-06 25.6 0.3 0.006 16.3 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EGO19228.1 - 0.0079 16.1 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain EutQ PF06249.12 EGO19228.1 - 0.023 14.5 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EGO19228.1 - 0.12 12.1 0.2 2 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Ribosomal_S7 PF00177.21 EGO19229.1 - 1.9e-26 92.5 0.5 2.7e-26 92.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Mito_carr PF00153.27 EGO19230.1 - 5.5e-28 96.7 3.7 8.6e-15 54.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 EGO19231.1 - 5e-38 131.1 21.9 7.1e-38 130.6 21.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO19231.1 - 3.1e-34 118.5 29.1 3.1e-34 118.5 29.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily BaxI_1 PF12811.7 EGO19231.1 - 2.9 7.4 15.6 0.52 9.8 0.2 2.9 1 1 0 3 3 3 0 Bax inhibitor 1 like GNAT_acetyltr_2 PF13718.6 EGO19232.1 - 4.4e-91 304.3 0.0 7.4e-91 303.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGO19232.1 - 9.6e-91 303.7 0.2 1.5e-90 303.0 0.2 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EGO19232.1 - 1.2e-66 223.9 0.0 5.5e-66 221.8 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EGO19232.1 - 7.3e-32 109.2 0.0 1.9e-31 107.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EGO19232.1 - 0.0013 18.5 0.0 0.038 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO19232.1 - 0.0059 16.9 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 EGO19232.1 - 0.075 13.5 0.0 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 EGO19233.1 - 5.4e-09 37.0 0.1 7.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO19233.1 - 0.00095 18.5 0.5 0.0013 18.0 0.5 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO19233.1 - 0.021 14.5 0.2 0.028 14.1 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AUDH_Cupin PF18637.1 EGO19233.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain Peptidase_M24 PF00557.24 EGO19234.1 - 4.4e-42 144.1 0.1 5.5e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 EGO19234.1 - 4.7 7.2 7.8 3.1 7.8 0.8 2.8 3 0 0 3 3 3 0 Protein trafficking PGA2 Abhydrolase_6 PF12697.7 EGO19235.1 - 2.3e-13 51.3 0.1 2.8e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO19235.1 - 1e-05 25.0 0.1 1.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO19235.1 - 4.9e-05 23.1 0.1 0.0001 22.0 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_88 PF07470.13 EGO19235.1 - 0.19 10.7 0.1 0.27 10.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Ion_trans PF00520.31 EGO19236.1 - 1.6e-18 66.8 20.5 2.3e-18 66.3 20.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGO19236.1 - 2.6e-11 43.3 4.5 2.6e-11 43.3 4.5 2.8 2 2 0 2 2 2 1 Ion channel YjfB_motility PF14070.6 EGO19236.1 - 0.068 13.3 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Putative motility protein Arg_repressor PF01316.21 EGO19236.1 - 0.19 11.5 1.0 0.34 10.7 1.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain zf-CCHC_3 PF13917.6 EGO19237.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO19237.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO19237.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO19237.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger COesterase PF00135.28 EGO19239.1 - 7e-73 246.2 0.0 8.9e-70 236.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Plavaka PF18759.1 EGO19241.1 - 3.9e-79 266.2 0.0 8.8e-37 127.0 0.0 3.3 1 1 2 3 3 3 3 Plavaka transposase Pkinase PF00069.25 EGO19245.1 - 7.5e-06 25.5 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19245.1 - 0.013 14.8 0.0 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase COesterase PF00135.28 EGO19246.1 - 4e-14 52.4 0.0 1.9e-11 43.5 0.1 2.9 1 1 1 2 2 2 2 Carboxylesterase family COQ9 PF08511.11 EGO19246.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 COQ9 zf-CCHC PF00098.23 EGO19248.1 - 7.9e-08 32.0 6.9 1.3e-07 31.3 3.8 2.5 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO19248.1 - 2.9e-07 30.6 2.0 3.8e-07 30.3 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO19248.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 EGO19249.1 - 2.6e-09 37.2 0.4 9.2e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO19249.1 - 4.2e-08 32.9 5.2 8.3e-08 32.0 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO19249.1 - 0.0075 16.2 2.5 0.02 14.9 2.5 1.7 1 0 0 1 1 1 1 Zinc knuckle GTP_CH_N PF12471.8 EGO19250.1 - 1.6e-90 302.0 0.0 2.3e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EGO19250.1 - 3.7e-15 55.9 0.0 7.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Abhydrolase_1 PF00561.20 EGO19252.1 - 3.2e-26 92.5 0.1 1.4e-19 70.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO19252.1 - 2.9e-24 85.6 0.0 3.8e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO19252.1 - 1.2e-19 71.8 0.0 1.5e-19 71.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EGO19252.1 - 9.4e-06 24.5 0.0 1.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 EGO19252.1 - 3.9e-05 23.7 0.0 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Ser_hydrolase PF06821.13 EGO19252.1 - 4.4e-05 23.4 1.9 0.0035 17.2 0.1 2.4 2 1 1 3 3 3 1 Serine hydrolase Abhydrolase_5 PF12695.7 EGO19252.1 - 5.5e-05 23.0 0.0 0.00038 20.3 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO19252.1 - 0.00012 21.9 3.2 0.0054 16.5 3.3 2.3 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 EGO19252.1 - 0.00014 21.5 0.1 0.18 11.3 0.0 2.2 1 1 1 2 2 2 2 Dienelactone hydrolase family DUF915 PF06028.11 EGO19252.1 - 0.0003 20.2 0.0 0.063 12.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 EGO19252.1 - 0.0012 18.8 0.0 0.0044 17.0 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 EGO19252.1 - 0.0024 18.0 0.0 0.0062 16.7 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 EGO19252.1 - 0.0029 17.1 0.2 0.0057 16.2 0.2 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGO19252.1 - 0.0048 16.8 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF5553 PF17707.1 EGO19252.1 - 0.0048 16.4 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5553) Esterase PF00756.20 EGO19252.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGO19252.1 - 0.0098 15.4 0.0 4 6.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 EGO19252.1 - 0.015 15.0 0.1 0.066 12.9 0.1 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGO19252.1 - 0.033 14.0 0.4 5.1 6.8 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 EGO19252.1 - 0.042 12.4 0.1 0.55 8.7 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGO19252.1 - 0.062 12.2 0.3 0.18 10.7 0.1 1.9 3 0 0 3 3 3 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 EGO19252.1 - 0.15 11.6 0.0 0.63 9.6 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Amidohydro_1 PF01979.20 EGO19253.1 - 2.2e-16 60.1 0.3 3.3e-16 59.5 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO19253.1 - 5.7e-09 35.9 0.2 8.4e-05 22.2 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family DUF3421 PF11901.8 EGO19254.1 - 5.7e-07 29.5 0.0 0.00015 21.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) VWA PF00092.28 EGO19254.1 - 0.00017 21.9 0.0 0.00047 20.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGO19254.1 - 0.0047 17.5 0.0 0.017 15.8 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Plavaka PF18759.1 EGO19256.1 - 6.2e-40 137.4 0.1 9.6e-40 136.8 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase FrhB_FdhB_C PF04432.13 EGO19256.1 - 0.17 11.7 2.6 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Sod_Fe_C PF02777.18 EGO19259.1 - 3e-34 117.2 0.3 5.2e-34 116.5 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGO19259.1 - 1.8e-31 108.5 3.7 3.5e-31 107.5 2.3 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Carn_acyltransf PF00755.20 EGO19260.1 - 4.9e-200 666.1 0.0 5.6e-200 665.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DRMBL PF07522.14 EGO19262.1 - 4.2e-08 33.3 0.0 1.3e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGO19262.1 - 0.0019 17.8 0.6 0.014 15.0 0.6 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO19262.1 - 0.087 12.8 0.2 0.3 11.1 0.2 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EGO19262.1 - 0.12 12.4 0.0 0.53 10.3 0.0 2.1 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain NAD_binding_6 PF08030.12 EGO19263.1 - 3.2e-05 24.1 0.0 9.8e-05 22.5 0.0 1.7 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Putative_PNPOx PF01243.20 EGO19263.1 - 3.2e-05 24.0 0.0 0.0017 18.5 0.0 2.9 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 EGO19263.1 - 0.00048 20.8 0.0 0.69 10.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Aminotran_1_2 PF00155.21 EGO19264.1 - 7.9e-37 127.3 0.0 9.3e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO19264.1 - 5.5e-05 21.9 0.0 8.1e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGO19264.1 - 0.00013 21.5 0.4 0.00019 20.9 0.4 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGO19264.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase ICMT PF04140.14 EGO19265.1 - 2.1e-13 50.5 0.0 4.3e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO19265.1 - 5.5e-11 42.8 0.1 5.9e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGO19265.1 - 0.00012 21.0 0.2 0.00016 20.6 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EGO19266.1 - 5.4e-12 46.0 0.1 2.5e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO19266.1 - 3.9e-09 36.8 0.6 1.3e-08 35.2 0.3 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGO19266.1 - 7e-07 28.4 0.1 9.8e-07 27.9 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGO19266.1 - 0.05 13.1 0.1 0.085 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Corona_7 PF02398.16 EGO19266.1 - 0.11 13.1 0.3 0.16 12.5 0.3 1.3 1 0 0 1 1 1 0 Coronavirus protein 7 MFS_1 PF07690.16 EGO19267.1 - 3.1e-18 65.8 38.6 5.8e-12 45.2 26.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO19267.1 - 4.5e-16 58.7 19.9 4.5e-14 52.2 19.9 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter Kri1 PF05178.12 EGO19268.1 - 0.044 14.3 0.0 0.14 12.8 0.0 1.7 1 1 0 1 1 1 0 KRI1-like family NADH_dh_m_C1 PF15088.6 EGO19269.1 - 0.14 11.8 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial PRP1_N PF06424.12 EGO19270.1 - 1e-49 168.7 2.9 1e-49 168.7 2.9 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGO19270.1 - 2.2e-26 90.3 28.7 0.012 16.4 0.3 14.1 5 4 10 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGO19270.1 - 1.4e-17 63.9 7.2 0.015 15.8 0.0 8.9 7 3 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO19270.1 - 1.9e-13 50.8 11.3 6.2e-05 23.6 0.0 6.7 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO19270.1 - 3.3e-07 29.9 1.6 0.27 11.4 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO19270.1 - 3.8e-05 24.0 6.3 4.1 8.2 0.0 7.5 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO19270.1 - 0.00051 20.3 0.4 14 6.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO19270.1 - 0.0021 18.3 0.7 2.5e+02 2.4 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO19270.1 - 0.0059 16.7 11.4 2 8.6 0.0 6.0 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO19270.1 - 0.013 15.3 0.1 7.4 6.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGO19270.1 - 0.018 15.2 0.2 7.8 7.0 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.8 EGO19270.1 - 0.023 13.6 0.2 7.2 5.4 0.0 3.5 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 EGO19270.1 - 0.061 13.0 7.1 1 9.0 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 EGO19270.1 - 0.13 12.0 0.7 6.1 6.6 0.0 3.8 3 1 1 4 4 4 0 TPR repeat FAT PF02259.23 EGO19270.1 - 0.14 11.3 10.0 2.5 7.3 4.8 4.4 1 1 0 2 2 2 0 FAT domain Ferritin PF00210.24 EGO19270.1 - 0.2 11.6 2.7 7.7 6.4 0.8 2.8 2 0 0 2 2 2 0 Ferritin-like domain APH PF01636.23 EGO19271.1 - 4.2e-16 59.6 0.1 1.1e-15 58.2 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGO19271.1 - 3.9e-06 26.0 0.1 3.1e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGO19271.1 - 9.2e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGO19271.1 - 0.00054 19.4 0.5 0.16 11.3 0.1 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family HipA_C PF07804.12 EGO19271.1 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 HipA-like C-terminal domain EcKinase PF02958.20 EGO19271.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EGO19271.1 - 0.013 15.1 0.8 0.049 13.2 0.1 1.9 2 0 0 2 2 2 0 RIO1 family SNN_transmemb PF09049.10 EGO19272.1 - 0.023 14.6 0.4 0.059 13.3 0.4 1.7 1 0 0 1 1 1 0 Stannin transmembrane PMP1_2 PF08114.11 EGO19272.1 - 0.032 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family NAD_binding_8 PF13450.6 EGO19273.1 - 6.7e-11 42.3 0.0 1.6e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO19273.1 - 2.8e-07 30.1 0.0 4.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGO19273.1 - 5e-05 21.9 0.2 0.0011 17.5 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 EGO19273.1 - 6.4e-05 23.0 0.4 0.00034 20.6 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EGO19273.1 - 0.0005 19.8 0.0 0.0032 17.1 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO19273.1 - 0.031 13.5 0.1 0.069 12.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DUF5601 PF18151.1 EGO19273.1 - 0.048 14.0 0.3 4.3 7.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) FAD_binding_2 PF00890.24 EGO19273.1 - 0.14 11.2 0.1 0.73 8.8 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain bZIP_1 PF00170.21 EGO19275.1 - 0.12 12.5 2.4 0.26 11.4 2.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 EGO19275.1 - 0.14 11.9 1.8 0.38 10.5 1.8 1.7 1 0 0 1 1 1 0 Septum formation initiator Bap31_Bap29_C PF18035.1 EGO19275.1 - 0.39 10.8 4.3 0.46 10.5 1.5 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain NAD_binding_8 PF13450.6 EGO19276.1 - 1e-09 38.5 0.0 2.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EGO19276.1 - 1.8e-07 30.0 0.7 2.6e-05 22.9 0.1 3.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO19276.1 - 2.8e-06 26.8 0.0 0.0014 17.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO19276.1 - 0.0002 21.1 0.0 0.0014 18.3 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO19276.1 - 0.0019 18.2 0.0 0.046 13.7 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EGO19276.1 - 0.022 14.0 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EGO19276.1 - 0.085 12.1 0.0 8 5.6 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 EGO19277.1 - 2e-08 34.0 0.3 1.2e-07 31.5 0.3 2.4 1 0 0 1 1 1 1 F-box-like DUF4763 PF15960.5 EGO19277.1 - 0.18 11.1 0.0 0.96 8.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) G-patch_2 PF12656.7 EGO19279.1 - 1.4e-20 73.2 0.2 5.7e-20 71.2 0.2 2.2 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EGO19279.1 - 0.06 13.2 0.6 0.06 13.2 0.6 2.1 2 0 0 2 2 2 0 G-patch domain Amidohydro_1 PF01979.20 EGO19280.1 - 2.2e-15 56.8 0.0 4.1e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO19280.1 - 5e-07 29.6 0.4 0.0022 17.5 0.2 3.0 2 1 1 3 3 3 2 Amidohydrolase family ADH_zinc_N PF00107.26 EGO19280.1 - 0.17 11.9 0.4 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Asp PF00026.23 EGO19281.1 - 5.8e-51 173.8 5.4 1.2e-50 172.7 5.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO19281.1 - 1.3e-07 32.1 3.8 5.2e-06 26.8 3.8 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO19281.1 - 0.00015 22.3 2.0 0.22 12.2 0.0 3.9 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EGO19281.1 - 0.00076 19.3 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGO19281.1 - 0.043 14.4 0.3 3.4 8.3 0.0 3.2 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease HECT PF00632.25 EGO19283.1 - 6.9e-96 321.3 0.0 8.1e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DAHP_synth_2 PF01474.16 EGO19284.1 - 4.2e-179 595.7 0.0 4.8e-179 595.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PEMT PF04191.13 EGO19285.1 - 8.1e-13 48.7 0.1 4.3e-12 46.4 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EGO19285.1 - 6e-12 45.8 0.1 6e-12 45.8 0.1 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EGO19285.1 - 4.8e-07 28.9 0.2 7.1e-07 28.3 0.2 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGO19285.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4646 PF15496.6 EGO19286.1 - 2.3e-18 67.0 0.0 3.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) FAD-oxidase_C PF02913.19 EGO19288.1 - 1.9e-55 188.2 0.0 2.7e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO19288.1 - 7.3e-30 103.5 0.5 1.6e-29 102.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Plavaka PF18759.1 EGO19293.1 - 1.5e-18 67.1 0.6 2.3e-18 66.5 0.6 1.3 1 0 0 1 1 1 1 Plavaka transposase M11L PF11099.8 EGO19293.1 - 0.075 13.3 0.4 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Apoptosis regulator M11L like VPS13 PF16908.5 EGO19294.1 - 8.3e-07 29.0 3.8 1.9e-06 27.9 3.8 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal ZZ PF00569.17 EGO19294.1 - 0.043 13.6 5.0 0.12 12.1 5.0 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF3040 PF11239.8 EGO19294.1 - 0.058 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CLZ PF16526.5 EGO19295.1 - 0.00071 19.9 2.1 0.0009 19.6 2.1 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 EGO19295.1 - 0.0089 16.3 1.4 0.016 15.5 1.4 1.6 1 1 0 1 1 1 1 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 EGO19295.1 - 0.014 15.6 0.6 0.016 15.3 0.6 1.1 1 0 0 1 1 1 0 Tropomyosin like DHR10 PF18595.1 EGO19295.1 - 0.018 15.1 0.7 0.022 14.8 0.7 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CCDC-167 PF15188.6 EGO19295.1 - 0.11 12.9 2.2 0.14 12.5 0.8 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PRKG1_interact PF15898.5 EGO19295.1 - 0.17 12.8 3.3 0.26 12.2 3.3 1.4 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain GMC_oxred_N PF00732.19 EGO19298.1 - 1.3e-53 182.3 0.0 2.4e-53 181.4 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO19298.1 - 6.8e-33 114.2 0.0 1.1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO19298.1 - 1.7e-05 24.1 0.2 3.6e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EGO19298.1 - 2.4e-05 24.1 0.4 0.00011 21.9 0.7 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO19298.1 - 0.00034 19.9 0.0 0.0053 16.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO19298.1 - 0.0008 18.6 1.2 0.11 11.5 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGO19298.1 - 0.0097 16.1 0.4 0.035 14.3 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO19298.1 - 0.017 15.7 0.2 1 10.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO19298.1 - 0.033 13.4 0.1 0.064 12.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGO19298.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGO19298.1 - 0.066 12.1 0.1 0.099 11.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.15 EGO19298.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Caleosin PF05042.13 EGO19299.1 - 1.5e-73 246.3 0.1 1.9e-73 246.0 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 EGO19299.1 - 0.46 10.1 3.1 15 5.4 0.1 3.1 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 EGO19299.1 - 0.53 10.3 3.5 19 5.5 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain Helicase_C PF00271.31 EGO19300.1 - 3.7e-16 59.4 0.0 1e-13 51.6 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EGO19300.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGO19300.1 - 0.017 15.8 0.1 0.055 14.2 0.1 2.0 1 0 0 1 1 1 0 RecQ zinc-binding CN_hydrolase PF00795.22 EGO19301.1 - 1.2e-15 57.6 0.0 4.1e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase LIAS_N PF16881.5 EGO19302.1 - 2.4e-23 82.6 0.1 1.5e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EGO19302.1 - 3.3e-14 53.6 0.0 5.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily zf-CCHC PF00098.23 EGO19303.1 - 5.4e-07 29.4 5.8 1.5e-06 28.0 5.8 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO19303.1 - 1.5e-06 28.3 1.9 3.2e-06 27.3 0.2 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO19303.1 - 0.0047 16.9 4.3 0.024 14.6 1.0 2.4 2 0 0 2 2 2 1 Zinc knuckle NYD-SP28_assoc PF14775.6 EGO19303.1 - 0.033 14.3 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain gag-asp_proteas PF13975.6 EGO19304.1 - 0.0054 17.3 0.0 0.0098 16.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO19304.1 - 0.0058 17.2 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO19304.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.6 1 1 1 2 2 2 0 Retroviral aspartyl protease TFIIF_alpha PF05793.12 EGO19304.1 - 0.16 10.5 0.1 0.2 10.2 0.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.16 EGO19309.1 - 1.3e-22 80.3 55.3 3e-17 62.6 37.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EGO19311.1 - 1.2e-38 133.1 0.0 1.7e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.18 EGO19311.1 - 0.0066 16.4 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Retrotrans_gag PF03732.17 EGO19311.1 - 0.11 12.8 0.7 0.47 10.8 0.3 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein SGS PF05002.15 EGO19314.1 - 1.6e-29 101.8 0.5 3.5e-29 100.7 0.5 1.6 1 0 0 1 1 1 1 SGS domain UvrD_C PF13361.6 EGO19314.1 - 2.6e-09 36.9 0.0 3.2e-05 23.5 0.0 3.1 3 1 1 4 4 4 2 UvrD-like helicase C-terminal domain CS PF04969.16 EGO19314.1 - 1.1e-08 36.0 0.1 2.7e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 CS domain UvrD-helicase PF00580.21 EGO19314.1 - 1.7e-06 27.8 0.1 0.00035 20.2 0.0 2.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGO19314.1 - 2.6e-06 27.8 0.0 2.3e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGO19314.1 - 2.9e-06 27.0 0.0 0.014 15.2 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EGO19314.1 - 3.6e-05 24.1 0.0 0.00087 19.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EGO19314.1 - 0.0065 16.1 0.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EGO19314.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EGO19314.1 - 0.15 11.8 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 EGO19315.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO19315.1 - 0.0083 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO19315.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain Mito_carr PF00153.27 EGO19317.1 - 4.5e-55 183.6 4.0 6e-18 64.6 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EGO19317.1 - 0.001 18.3 1.6 0.015 14.5 0.2 2.5 3 0 0 3 3 3 2 Gammaproteobacterial serine protease tRNA_int_end_N2 PF12928.7 EGO19318.1 - 7.1e-21 74.2 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGO19318.1 - 0.0038 16.9 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain RhoGAP PF00620.27 EGO19319.1 - 9.8e-33 113.1 0.0 1.6e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EGO19319.1 - 1.1e-30 106.5 0.1 2.1e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGO19319.1 - 0.00013 21.8 0.1 0.00039 20.2 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain Ndc1_Nup PF09531.10 EGO19319.1 - 3.5 6.2 5.0 2.3 6.8 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Cation_efflux PF01545.21 EGO19320.1 - 3.9e-53 180.2 1.6 6.7e-53 179.4 1.6 1.4 1 1 0 1 1 1 1 Cation efflux family DUF2569 PF10754.9 EGO19320.1 - 0.25 11.8 5.4 7 7.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) MASE4 PF17158.4 EGO19320.1 - 0.74 9.0 10.5 0.019 14.2 3.7 1.8 2 1 0 2 2 2 0 Membrane-associated sensor, integral membrane domain DUF2157 PF09925.9 EGO19320.1 - 4.7 7.0 7.5 14 5.5 2.7 2.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Thioredoxin_16 PF18569.1 EGO19321.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF974 PF06159.13 EGO19322.1 - 0.087 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF974) DDE_Tnp_4 PF13359.6 EGO19323.1 - 5.5e-18 65.1 0.0 8.8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO19323.1 - 8.9e-07 28.8 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Plavaka PF18759.1 EGO19324.1 - 2.5e-27 95.9 0.0 4.7e-27 95.1 0.0 1.5 1 1 0 1 1 1 1 Plavaka transposase zf-CCHC PF00098.23 EGO19325.1 - 3.1e-08 33.3 2.8 3.1e-08 33.3 2.8 1.8 2 0 0 2 2 2 1 Zinc knuckle CpXC PF14353.6 EGO19325.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 CpXC protein Retrotrans_gag PF03732.17 EGO19326.1 - 1.5e-07 31.6 0.7 2.5e-07 30.9 0.3 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein TPR_12 PF13424.6 EGO19327.1 - 0.075 13.3 0.3 0.67 10.3 0.3 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat SPRY PF00622.28 EGO19328.1 - 1.2e-13 51.2 0.0 1.9e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain GDA1_CD39 PF01150.17 EGO19329.1 - 5.9e-88 295.3 0.0 8.1e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SecD-TM1 PF13721.6 EGO19329.1 - 0.23 11.9 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 SecD export protein N-terminal TM region bZIP_1 PF00170.21 EGO19330.1 - 8.1e-06 25.8 10.2 1.1e-05 25.4 9.7 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO19330.1 - 2.7e-05 24.2 12.3 2.7e-05 24.2 12.3 1.6 1 1 1 2 2 2 1 Basic region leucine zipper eIF-3c_N PF05470.12 EGO19330.1 - 0.1 10.9 2.7 0.41 8.9 2.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EGO19330.1 - 1.3 7.2 6.3 1.7 6.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_88 PF07470.13 EGO19332.1 - 2.1e-15 56.7 0.2 3e-15 56.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4880 PF16220.5 EGO19333.1 - 0.091 12.7 0.6 0.18 11.7 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) BRK PF07533.16 EGO19333.1 - 0.13 11.9 0.3 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 BRK domain DDE_Tnp_4 PF13359.6 EGO19335.1 - 3.4e-10 39.8 0.0 5.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_A PF00476.20 EGO19335.1 - 0.15 11.0 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase family A Glyco_hydro_88 PF07470.13 EGO19336.1 - 2.2e-15 56.6 0.1 3.7e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 BTB PF00651.31 EGO19337.1 - 4.4e-06 26.9 0.0 2.3e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain FR47 PF08445.10 EGO19338.1 - 2.2e-10 40.4 0.0 1.5e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGO19338.1 - 3e-10 40.4 0.0 4.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO19338.1 - 4.1e-10 39.9 0.0 1.1e-09 38.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO19338.1 - 2e-09 37.5 0.0 1.9e-08 34.3 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO19338.1 - 3.6e-05 24.4 0.0 8.1e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO19338.1 - 0.00056 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EGO19338.1 - 0.0033 16.9 0.0 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EGO19338.1 - 0.0085 16.2 0.0 0.029 14.4 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGO19338.1 - 0.022 14.7 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PDT PF00800.18 EGO19339.1 - 1e-48 165.6 0.0 1.3e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase MFS_1 PF07690.16 EGO19340.1 - 9.1e-28 97.2 37.3 7.2e-19 67.9 6.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO19340.1 - 3e-23 82.4 19.1 6.5e-23 81.3 0.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGO19340.1 - 0.33 10.2 23.6 0.064 12.5 4.1 2.7 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB Kin17_mid PF10357.9 EGO19342.1 - 1.5e-49 167.1 0.6 2.2e-49 166.5 0.6 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EGO19342.1 - 0.00047 20.5 4.0 0.00093 19.5 4.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO19342.1 - 0.013 15.7 3.1 0.025 14.9 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGO19342.1 - 0.013 15.8 2.2 0.056 13.8 0.7 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2407_C PF13373.6 EGO19343.1 - 1.3e-21 77.3 8.1 4e-18 65.9 2.8 2.8 2 1 0 2 2 2 2 DUF2407 C-terminal domain DUF2407 PF10302.9 EGO19343.1 - 1.1e-18 67.7 0.0 2.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EGO19343.1 - 1.3e-06 28.0 0.0 7.4e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family AI-2E_transport PF01594.16 EGO19343.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter IBN_N PF03810.19 EGO19344.1 - 2.2e-09 37.1 0.0 2.5e-06 27.3 0.0 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain RIX1 PF08167.12 EGO19344.1 - 0.00084 19.1 0.0 0.0048 16.7 0.0 2.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Cse1 PF08506.10 EGO19344.1 - 0.0031 16.4 0.0 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 Cse1 HEAT PF02985.22 EGO19344.1 - 0.012 15.7 0.2 9.5 6.8 0.1 3.6 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 EGO19344.1 - 0.02 15.3 0.4 0.72 10.3 0.2 3.0 2 0 0 2 2 2 0 HEAT repeats Telomere_reg-2 PF10193.9 EGO19344.1 - 0.048 14.1 3.1 3.3 8.2 0.5 3.1 3 0 0 3 3 3 0 Telomere length regulation protein RTP1_C1 PF10363.9 EGO19344.1 - 0.084 13.1 0.2 0.35 11.1 0.2 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGO19344.1 - 0.14 12.7 1.7 66 4.2 0.1 4.5 4 1 0 4 4 4 0 HEAT-like repeat Actin PF00022.19 EGO19345.1 - 5.5e-73 245.9 0.0 3.2e-72 243.4 0.0 1.8 1 1 0 1 1 1 1 Actin Zn_clus PF00172.18 EGO19346.1 - 3.1e-08 33.6 7.2 3.1e-08 33.6 7.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 EGO19346.1 - 0.12 12.3 2.3 1.1 9.2 0.4 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat G_path_suppress PF15991.5 EGO19346.1 - 8.2 6.5 9.9 15 5.6 9.9 1.6 1 1 0 1 1 1 0 G-protein pathway suppressor PSS PF03034.15 EGO19353.1 - 4.1e-116 387.5 10.2 5.2e-116 387.2 10.2 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3918 PF13056.6 EGO19353.1 - 0.052 13.2 0.2 0.18 11.4 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GH3 PF03321.13 EGO19354.1 - 1.5e-72 245.2 0.0 1.7e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter UBA_2 PF08587.11 EGO19354.1 - 0.095 12.8 0.1 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) GSDH PF07995.11 EGO19354.1 - 0.12 11.6 0.0 15 4.8 0.0 2.1 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Pkinase PF00069.25 EGO19357.1 - 1.5e-07 31.1 0.0 4.9e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19357.1 - 0.016 14.5 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Herpes_UL56 PF04534.12 EGO19359.1 - 0.071 12.6 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Nop PF01798.18 EGO19360.1 - 1.8e-83 279.5 0.6 4e-83 278.4 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGO19360.1 - 4.7e-21 74.9 1.2 4.7e-21 74.9 1.2 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain LamB_YcsF PF03746.16 EGO19363.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 LamB/YcsF family Flu_PA PF00603.17 EGO19365.1 - 0.065 11.4 0.0 0.079 11.1 0.0 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA HNF-1_N PF04814.13 EGO19366.1 - 0.088 13.4 1.0 0.11 13.1 1.0 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF4193 PF13834.6 EGO19366.1 - 1.8 9.1 6.1 5.2 7.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Plavaka PF18759.1 EGO19367.1 - 1.7e-121 405.4 0.0 2.3e-121 405.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase RNA_pol_Rpb8 PF03870.15 EGO19374.1 - 2e-47 160.9 0.0 2.3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Oxidored_molyb PF00174.19 EGO19375.1 - 7e-47 159.2 0.0 1.4e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGO19375.1 - 8.6e-21 74.4 1.8 1.4e-20 73.7 1.8 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain F-box PF00646.33 EGO19380.1 - 2e-06 27.5 0.0 5.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO19380.1 - 1.3e-05 25.0 0.2 5.5e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EGO19380.1 - 0.017 15.0 0.8 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 F-box YTH PF04146.15 EGO19381.1 - 3.4e-62 209.3 0.0 6.3e-62 208.4 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain WD40 PF00400.32 EGO19386.1 - 4e-26 90.7 1.6 1.8e-07 31.7 0.3 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO19386.1 - 2.2e-10 40.7 0.1 0.0038 17.5 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO19386.1 - 3.4e-07 29.3 0.7 8.4e-05 21.4 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO19386.1 - 0.00037 19.6 1.9 0.27 10.2 0.3 3.5 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGO19386.1 - 0.00083 19.0 0.2 0.0017 18.0 0.1 1.6 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 EGO19386.1 - 0.0035 15.9 0.0 0.0056 15.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 EGO19386.1 - 0.031 13.6 0.1 0.71 9.1 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain Gmad1 PF10647.9 EGO19386.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DUF5046 PF16465.5 EGO19386.1 - 0.065 12.7 0.4 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) HAD_2 PF13419.6 EGO19389.1 - 8.4e-16 58.6 0.0 1e-10 42.0 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO19389.1 - 8.4e-13 49.1 0.0 2.8e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO19389.1 - 0.00013 22.0 0.7 0.00025 21.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Glyco_hydro_71 PF03659.14 EGO19393.1 - 9.4e-118 393.3 14.5 1.1e-117 393.1 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 FYRN PF05964.14 EGO19394.1 - 1.9e-18 66.0 0.2 3.8e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EGO19394.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus AA_permease PF00324.21 EGO19395.1 - 3e-107 359.2 40.5 3.6e-107 358.9 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO19395.1 - 1.6e-35 122.7 43.8 2.1e-35 122.4 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease OST3_OST6 PF04756.13 EGO19395.1 - 0.26 10.6 3.9 0.64 9.3 3.9 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AA_permease PF00324.21 EGO19396.1 - 6.4e-100 335.0 39.9 7.7e-100 334.8 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO19396.1 - 2.5e-32 112.3 41.2 3.4e-32 111.8 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease OST3_OST6 PF04756.13 EGO19396.1 - 0.25 10.7 3.9 0.61 9.4 3.9 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TAF PF02969.17 EGO19397.1 - 6.2e-26 90.4 0.1 1.1e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EGO19397.1 - 7.5e-15 55.0 0.0 1.9e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 EGO19397.1 - 0.0011 19.3 2.5 0.0014 18.9 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGO19397.1 - 0.0048 16.9 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGO19397.1 - 0.011 15.8 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HEAT_EZ PF13513.6 EGO19397.1 - 0.058 13.9 2.0 4.3 7.9 0.0 4.1 3 1 1 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 EGO19397.1 - 0.072 13.5 0.5 3.6 8.1 0.0 3.1 3 1 0 3 3 3 0 HEAT repeats DUF3385 PF11865.8 EGO19397.1 - 0.19 11.6 2.6 0.86 9.5 1.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3385) Glyco_hydro_61 PF03443.14 EGO19398.1 - 4.4e-52 177.0 0.2 5.3e-52 176.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 EGO19398.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory YtzH PF14165.6 EGO19400.1 - 0.27 11.7 0.2 0.27 11.7 0.2 2.2 2 0 0 2 2 2 0 YtzH-like protein KDZ PF18758.1 EGO19401.1 - 3.2e-26 92.3 1.3 6.7e-20 71.7 0.1 2.0 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase MFS_1 PF07690.16 EGO19403.1 - 2.2e-16 59.7 29.8 2.2e-16 59.7 29.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO19403.1 - 4.7e-14 52.4 5.5 4.7e-14 52.4 5.5 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 EGO19403.1 - 0.074 12.0 11.1 0.05 12.6 2.6 2.8 3 0 0 3 3 3 0 PUCC protein Pkinase PF00069.25 EGO19404.1 - 5.3e-49 166.9 0.0 2e-48 165.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19404.1 - 1.1e-23 83.8 0.0 3e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO19404.1 - 0.00022 20.6 0.2 0.0085 15.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGO19404.1 - 0.002 18.1 0.3 0.043 13.7 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO19404.1 - 0.0055 16.1 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO19404.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGO19404.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Spindle_Spc25 PF08234.12 EGO19405.1 - 2.1e-23 82.3 1.3 4.1e-23 81.4 0.3 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 FapA PF03961.13 EGO19405.1 - 0.00025 19.8 5.0 0.00032 19.4 5.0 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A CENP-K PF11802.8 EGO19405.1 - 0.00065 19.3 3.9 0.00086 19.0 3.9 1.1 1 0 0 1 1 1 1 Centromere-associated protein K Spc7 PF08317.11 EGO19405.1 - 0.0022 17.0 7.4 0.0028 16.6 7.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 EGO19405.1 - 0.0026 16.8 5.5 0.0034 16.3 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Filament PF00038.21 EGO19405.1 - 0.003 17.2 4.5 0.0044 16.6 4.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein Rootletin PF15035.6 EGO19405.1 - 0.0085 16.1 6.1 0.011 15.7 6.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF4019 PF13211.6 EGO19405.1 - 0.052 13.9 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) ATG16 PF08614.11 EGO19405.1 - 0.055 13.7 5.9 0.084 13.1 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EGO19405.1 - 0.06 13.4 9.1 0.59 10.2 9.1 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1540 PF07561.11 EGO19405.1 - 0.069 13.5 1.6 7.4 6.9 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) CorA PF01544.18 EGO19405.1 - 0.07 12.4 1.5 0.12 11.7 0.9 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EGO19405.1 - 0.12 12.4 2.0 0.26 11.4 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.13 EGO19405.1 - 0.17 12.0 3.8 0.096 12.8 1.2 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CLZ PF16526.5 EGO19405.1 - 0.22 11.9 3.9 0.19 12.1 0.9 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 EGO19405.1 - 0.29 10.9 9.8 0.44 10.4 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LURAP PF14854.6 EGO19405.1 - 0.38 10.7 1.9 15 5.6 0.2 2.3 1 1 1 2 2 2 0 Leucine rich adaptor protein YabA PF06156.13 EGO19405.1 - 0.5 11.0 5.4 1.2 9.8 4.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 EGO19405.1 - 0.63 10.5 14.4 5.9 7.3 14.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 EGO19405.1 - 0.77 10.3 13.4 6.4 7.3 13.4 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 EGO19405.1 - 7.6 7.0 8.8 17 5.9 8.5 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc24 PF08286.11 EGO19405.1 - 9.5 6.5 7.4 8.2 6.7 1.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 zf-ACC PF17848.1 EGO19406.1 - 0.0079 16.2 0.3 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain DUF2863 PF11062.8 EGO19406.1 - 0.18 10.2 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) DMPK_coil PF08826.10 EGO19408.1 - 0.033 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like rve PF00665.26 EGO19409.1 - 5.3e-05 23.4 0.0 0.0014 18.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO19409.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3527 PF12043.8 EGO19411.1 - 0.0044 16.7 0.2 0.005 16.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) CDC45 PF02724.14 EGO19413.1 - 0.0025 16.2 2.8 0.002 16.5 2.8 1.2 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 EGO19413.1 - 0.004 17.3 13.9 0.0066 16.6 13.9 1.4 1 0 0 1 1 1 1 YL1 nuclear protein SR-25 PF10500.9 EGO19413.1 - 0.017 14.7 11.7 0.028 14.0 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGO19413.1 - 0.033 13.5 14.6 0.048 13.0 14.6 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 EGO19413.1 - 3.5 7.3 18.9 6.5 6.4 18.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 EGO19413.1 - 5.7 5.9 10.1 2.2 7.2 7.9 1.5 2 0 0 2 2 2 0 Pes-10 DNA_pol_phi PF04931.13 EGO19413.1 - 6.3 4.8 15.7 9.5 4.2 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi NosD PF05048.13 EGO19414.1 - 0.014 14.6 0.2 0.023 13.9 0.2 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) ARHGEF5_35 PF15441.6 EGO19414.1 - 0.071 12.1 0.2 0.098 11.6 0.2 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 TB2_DP1_HVA22 PF03134.19 EGO19415.1 - 2.3e-26 91.5 7.3 4.7e-26 90.5 7.3 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ost5 PF05251.12 EGO19416.1 - 2.5e-17 62.9 9.2 2.9e-17 62.7 9.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF3792 PF12670.7 EGO19416.1 - 0.0047 17.1 2.3 0.0056 16.8 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) ABC2_membrane_3 PF12698.7 EGO19416.1 - 0.055 12.6 5.6 0.063 12.4 5.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ATP19 PF11022.8 EGO19416.1 - 0.36 11.2 0.9 0.78 10.2 0.1 1.8 1 1 1 2 2 2 0 ATP synthase subunit K QCR10 PF09796.9 EGO19416.1 - 1.1 9.3 6.5 5 7.3 1.2 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TFIIS_C PF01096.18 EGO19417.1 - 1.1e-17 63.6 8.0 1.3e-17 63.3 0.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGO19417.1 - 1.2e-07 31.5 5.9 5.7e-07 29.3 0.5 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EGO19417.1 - 5.2e-05 23.2 6.5 0.01 15.8 0.3 2.5 2 1 0 2 2 2 2 Double zinc ribbon Baculo_LEF5_C PF11792.8 EGO19417.1 - 0.0031 17.1 4.0 0.011 15.4 0.6 2.5 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 EGO19417.1 - 0.0034 17.3 6.8 0.017 15.1 0.6 2.7 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zf-RING_7 PF02591.15 EGO19417.1 - 0.0042 17.2 5.2 1.6 8.9 0.0 4.0 4 0 0 4 4 4 1 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 EGO19417.1 - 0.0046 16.3 10.1 0.89 9.1 0.2 3.9 4 0 0 4 4 4 2 zinc-ribbon domain zinc_ribbon_10 PF10058.9 EGO19417.1 - 0.0051 16.5 3.7 12 5.7 0.0 3.9 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein IBR PF01485.21 EGO19417.1 - 0.0065 16.7 9.3 0.013 15.7 0.2 2.8 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Mu-like_Com PF10122.9 EGO19417.1 - 0.0081 15.6 0.6 3 7.3 0.0 2.4 2 0 0 2 2 2 1 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.11 EGO19417.1 - 0.016 15.2 7.3 0.43 10.5 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain NPM1-C PF16276.5 EGO19417.1 - 0.016 15.2 0.3 0.036 14.0 0.3 1.6 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain DNA_ligase_ZBD PF03119.16 EGO19417.1 - 0.023 14.7 0.9 7.2 6.7 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain HydF_tetramer PF18133.1 EGO19417.1 - 0.043 13.6 0.4 0.043 13.6 0.4 1.5 1 1 0 1 1 1 0 Hydrogen maturase F tetramerization domain UPF0167 PF03691.14 EGO19417.1 - 0.064 13.0 0.6 0.064 13.0 0.6 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) PhnA_Zn_Ribbon PF08274.12 EGO19417.1 - 0.094 12.7 13.9 3.2 7.8 0.4 3.7 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Lar_restr_allev PF14354.6 EGO19417.1 - 0.2 12.0 8.3 1.6 9.2 0.9 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar PHD PF00628.29 EGO19417.1 - 0.26 11.2 10.1 2.5 8.1 1.0 2.8 2 1 1 3 3 3 0 PHD-finger PADR1 PF08063.12 EGO19417.1 - 0.35 10.7 7.1 6.7 6.6 0.2 3.5 4 0 0 4 4 4 0 PADR1 (NUC008) domain zinc_ribbon_9 PF14369.6 EGO19417.1 - 0.39 11.0 9.0 26 5.2 3.0 3.7 3 1 1 4 4 4 0 zinc-ribbon DUF2387 PF09526.10 EGO19417.1 - 0.41 10.8 8.7 3 8.0 1.6 2.8 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Gmx_para_CXXCG PF09535.10 EGO19417.1 - 0.46 9.7 2.6 0.26 10.5 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) DUF3268 PF11672.8 EGO19417.1 - 0.51 10.7 5.6 0.22 11.9 1.2 2.3 2 1 1 3 3 3 0 zinc-finger-containing domain GFA PF04828.14 EGO19417.1 - 0.64 10.4 5.7 3 8.3 0.4 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 EGO19417.1 - 0.75 9.5 10.7 11 5.8 0.4 3.1 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.10 EGO19417.1 - 0.77 9.5 0.0 0.77 9.5 0.0 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.6 EGO19417.1 - 1 9.1 14.5 1.8 8.4 0.1 3.4 3 1 0 3 3 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EGO19417.1 - 1.2 9.3 8.9 1.5 9.0 1.1 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-UBR PF02207.20 EGO19417.1 - 1.4 9.1 10.4 0.43 10.8 1.3 3.0 2 2 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) UPF0547 PF10571.9 EGO19417.1 - 1.6 8.9 12.0 2.5 8.3 0.0 3.4 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 EGO19417.1 - 1.6 8.7 12.8 0.54 10.2 1.7 3.4 2 2 0 2 2 2 0 Nudix N-terminal zf_UBZ PF18439.1 EGO19417.1 - 2.1 8.0 10.0 9.8 5.9 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 EGO19417.1 - 2.2 8.0 8.1 9.8 6.0 0.9 3.4 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 EGO19417.1 - 2.3 8.2 11.6 8.7 6.4 0.2 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGO19417.1 - 2.4 8.3 15.5 8 6.7 0.6 3.8 2 2 1 4 4 4 0 Zinc ribbon domain zf-LITAF-like PF10601.9 EGO19417.1 - 2.6 8.4 9.5 20 5.5 0.2 3.9 4 1 0 4 4 4 0 LITAF-like zinc ribbon domain zf-IS66 PF13005.7 EGO19417.1 - 2.7 8.5 12.2 2.2 8.7 0.1 3.4 3 1 1 4 4 3 0 zinc-finger binding domain of transposase IS66 RecR PF02132.15 EGO19417.1 - 2.9 7.5 7.5 0.71 9.5 0.5 2.5 3 0 0 3 3 2 0 RecR protein Rubredoxin_2 PF18073.1 EGO19417.1 - 3.1 7.6 12.0 10 5.9 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain Ribosomal_S27e PF01667.17 EGO19417.1 - 3.6 7.4 7.4 3 7.6 1.0 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 zf-C4_Topoisom PF01396.19 EGO19417.1 - 4.3 7.2 8.9 10 6.0 0.5 3.4 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-RING_10 PF16685.5 EGO19417.1 - 5.5 7.2 9.4 1.9 8.7 0.4 2.8 2 2 0 2 2 2 0 zinc RING finger of MSL2 DUF35_N PF12172.8 EGO19417.1 - 6 6.9 8.2 22 5.1 0.1 3.3 4 0 0 4 4 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_15 PF17032.5 EGO19417.1 - 8.7 7.2 11.7 1.2e+02 3.6 0.1 3.1 1 1 0 2 2 2 0 zinc-ribbon family Peptidase_M1 PF01433.20 EGO19420.1 - 1.3e-36 126.2 0.0 1.8e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGO19420.1 - 9e-30 103.1 0.0 2e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGO19420.1 - 9.2e-17 61.8 0.0 1.8e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain GET2 PF08690.10 EGO19421.1 - 0.37 10.4 4.1 3.4 7.3 4.1 2.2 1 1 0 1 1 1 0 GET complex subunit GET2 YL1 PF05764.13 EGO19422.1 - 2.6e-33 116.2 12.5 3.6e-33 115.7 12.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 EGO19422.1 - 2.4e-11 43.2 0.1 4.4e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MutS_V PF00488.21 EGO19423.1 - 9.8e-53 179.0 0.2 2.5e-25 89.6 0.0 2.4 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 EGO19423.1 - 7.6e-31 107.8 4.0 7.6e-31 107.8 4.0 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGO19423.1 - 3.1e-09 37.1 0.2 7e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGO19423.1 - 0.0015 18.8 0.2 0.0073 16.6 0.1 2.3 2 1 0 2 2 2 1 MutS domain II Epsilon_antitox PF08998.11 EGO19423.1 - 0.044 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial epsilon antitoxin WG_beta_rep PF14903.6 EGO19424.1 - 0.074 13.4 0.9 0.12 12.7 0.3 1.7 2 0 0 2 2 2 0 WG containing repeat DAO PF01266.24 EGO19425.1 - 1.2e-28 100.7 0.2 3.5e-28 99.2 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO19425.1 - 0.0088 16.3 0.1 0.0088 16.3 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO19425.1 - 0.032 13.5 0.1 0.087 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Vps35 PF03635.17 EGO19427.1 - 0 1019.6 4.9 0 1019.4 4.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 EGO19427.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Endoribonuclease L-PSP BCIP PF13862.6 EGO19429.1 - 2.4e-65 220.2 0.0 3e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Pro_dh PF01619.18 EGO19430.1 - 4.1e-56 190.7 0.1 5.2e-55 187.1 0.1 2.1 1 1 0 1 1 1 1 Proline dehydrogenase TIP120 PF08623.10 EGO19431.1 - 1.8e-59 200.3 3.1 2.6e-58 196.5 0.2 3.7 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EGO19431.1 - 1.6e-14 54.1 10.8 0.11 13.0 0.0 8.2 6 1 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 EGO19431.1 - 2.6e-13 50.2 20.3 0.011 16.2 0.2 11.2 11 0 0 11 11 11 3 HEAT-like repeat HEAT PF02985.22 EGO19431.1 - 2.7e-12 45.8 25.0 0.06 13.6 0.0 12.8 15 0 0 15 15 14 2 HEAT repeat Cnd1 PF12717.7 EGO19431.1 - 1.1e-10 41.8 6.8 0.82 9.7 0.1 7.3 6 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGO19431.1 - 9.8e-08 32.5 1.0 1.3 9.7 0.0 7.3 7 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGO19431.1 - 1.4e-07 31.3 9.7 0.0088 15.6 0.1 6.2 6 1 0 6 6 6 2 CLASP N terminal MMS19_C PF12460.8 EGO19431.1 - 4.4e-07 29.4 22.9 0.085 12.0 0.1 5.4 4 2 1 5 5 5 4 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 EGO19431.1 - 1.3e-06 27.3 9.8 0.0096 14.5 0.0 6.2 5 1 0 6 6 6 2 Adaptin N terminal region Telomere_reg-2 PF10193.9 EGO19431.1 - 1.8e-06 28.4 1.3 0.0092 16.4 0.0 3.9 3 0 0 3 3 3 1 Telomere length regulation protein RTP1_C1 PF10363.9 EGO19431.1 - 1e-05 25.7 1.4 0.03 14.5 0.1 5.0 3 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 EGO19431.1 - 0.00015 21.4 8.4 3.1 7.2 0.0 5.1 4 1 1 5 5 5 3 Tti2 family DUF3385 PF11865.8 EGO19431.1 - 0.00019 21.4 4.8 0.0032 17.4 0.0 4.8 7 0 0 7 7 7 1 Domain of unknown function (DUF3385) ParcG PF10274.9 EGO19431.1 - 0.00092 19.4 3.6 0.77 9.9 0.0 5.2 6 0 0 6 6 6 1 Parkin co-regulated protein V-ATPase_H_C PF11698.8 EGO19431.1 - 0.012 15.7 0.5 0.29 11.3 0.2 3.4 3 0 0 3 3 3 0 V-ATPase subunit H TAF6_C PF07571.13 EGO19431.1 - 0.029 14.7 0.0 18 5.8 0.0 4.4 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Iron_permease PF04120.12 EGO19431.1 - 0.051 13.3 0.3 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 Low affinity iron permease FANCI_S2 PF14676.6 EGO19431.1 - 0.24 11.7 2.8 5.7 7.2 0.0 4.2 4 0 0 4 4 4 0 FANCI solenoid 2 AAA PF00004.29 EGO19433.1 - 1.5e-41 141.9 0.0 3.1e-41 140.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGO19433.1 - 7.1e-28 96.4 0.2 2.3e-27 94.8 0.2 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGO19433.1 - 6.6e-22 77.4 6.3 1.3e-21 76.4 6.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGO19433.1 - 2.4e-07 30.4 0.0 7.5e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO19433.1 - 4.4e-06 27.2 0.2 0.00083 19.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGO19433.1 - 9.3e-06 25.5 0.0 3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO19433.1 - 1.2e-05 25.3 0.0 4.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGO19433.1 - 5.1e-05 23.1 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGO19433.1 - 5.4e-05 23.5 0.9 0.0051 17.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGO19433.1 - 0.00015 22.3 0.4 0.0047 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGO19433.1 - 0.00024 21.1 0.1 0.00095 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGO19433.1 - 0.0005 19.4 0.3 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EGO19433.1 - 0.00095 19.3 0.1 0.0049 17.0 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.14 EGO19433.1 - 0.002 18.3 0.0 0.0084 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGO19433.1 - 0.0033 16.6 0.0 0.0068 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGO19433.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGO19433.1 - 0.0084 15.7 0.2 0.81 9.2 0.1 2.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO19433.1 - 0.011 16.1 0.0 0.011 16.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ATPase PF06745.13 EGO19433.1 - 0.019 14.3 0.1 6.3 6.1 0.0 2.3 1 1 1 2 2 2 0 KaiC DUF4407 PF14362.6 EGO19433.1 - 0.02 14.3 1.3 0.028 13.8 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_17 PF13207.6 EGO19433.1 - 0.024 15.1 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGO19433.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EGO19433.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TPR_3 PF07720.12 EGO19433.1 - 0.067 13.2 1.4 0.17 11.9 1.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_7 PF12775.7 EGO19433.1 - 0.067 12.7 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EGO19433.1 - 0.071 13.0 1.4 1.4 8.7 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea PhoH PF02562.16 EGO19433.1 - 0.073 12.5 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EGO19433.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EGO19433.1 - 0.17 11.6 0.0 0.61 9.8 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain V-ATPase_G_2 PF16999.5 EGO19433.1 - 0.32 11.4 4.2 0.57 10.6 4.2 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TPR_2 PF07719.17 EGO19433.1 - 0.73 10.1 3.2 10 6.5 0.4 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EGO19434.1 - 1.3e-56 191.9 0.0 1.5e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19434.1 - 1.1e-24 87.1 0.0 1.9e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO19434.1 - 1.5e-05 24.5 0.6 0.00014 21.3 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGO19434.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO19434.1 - 0.053 13.1 0.0 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGO19434.1 - 0.058 13.3 0.0 3.5 7.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L19e PF01280.20 EGO19435.1 - 3e-61 205.7 10.7 3e-61 205.7 10.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 EGO19435.1 - 0.0009 18.9 0.0 0.0037 16.9 0.0 2.0 2 0 0 2 2 2 1 S4 domain Lant_dehydr_C PF14028.6 EGO19435.1 - 0.0074 15.9 0.7 0.0093 15.5 0.4 1.3 1 1 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term MOZ_SAS PF01853.18 EGO19436.1 - 7.6e-62 208.1 0.1 1.1e-61 207.6 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGO19436.1 - 2e-20 72.1 1.8 2.3e-20 72.0 0.2 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGO19436.1 - 0.0017 18.7 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO19436.1 - 0.01 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Tudor-knot PF11717.8 EGO19437.1 - 2.8e-10 39.9 0.5 4.1e-10 39.4 0.5 1.3 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Agenet PF05641.12 EGO19437.1 - 0.057 13.9 0.1 0.068 13.7 0.1 1.3 1 0 0 1 1 1 0 Agenet domain COesterase PF00135.28 EGO19438.1 - 7.4e-70 236.3 0.0 9.1e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO19438.1 - 3.1e-05 24.0 0.2 0.00024 21.0 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.7 EGO19440.1 - 0.0088 15.9 0.5 0.015 15.1 0.5 1.5 1 0 0 1 1 1 1 F-box-like EphA2_TM PF14575.6 EGO19442.1 - 0.027 15.4 0.0 0.047 14.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_glycop PF01528.16 EGO19442.1 - 0.053 12.4 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF4083 PF13314.6 EGO19442.1 - 0.079 12.9 0.8 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) HSDR_N PF04313.14 EGO19443.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Phosphoesterase PF04185.14 EGO19445.1 - 4.5e-26 91.9 6.2 3.2e-25 89.1 6.2 2.0 1 1 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 EGO19446.1 - 6.7e-44 148.7 6.2 1.8e-43 147.3 2.6 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO19446.1 - 4.1e-37 127.0 5.8 1.9e-34 118.3 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGO19446.1 - 2.7e-29 102.3 1.6 1.1e-28 100.4 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Monooxygenase_B PF04744.12 EGO19446.1 - 0.13 11.1 0.8 0.48 9.2 0.1 1.9 2 0 0 2 2 2 0 Monooxygenase subunit B protein NmrA PF05368.13 EGO19447.1 - 2.6e-17 63.2 0.0 3.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO19447.1 - 3.1e-09 37.0 0.0 7.9e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO19447.1 - 0.00034 20.2 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGO19447.1 - 0.0038 16.7 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO19447.1 - 0.022 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1949 PF09186.11 EGO19447.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Biotin_carb_N PF00289.22 EGO19447.1 - 0.14 12.7 0.2 0.51 10.9 0.0 1.9 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain Glyco_trans_1_4 PF13692.6 EGO19448.1 - 2.2e-07 31.4 0.0 4.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGO19448.1 - 6.9e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGO19448.1 - 0.0034 17.8 0.0 0.0064 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGO19448.1 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO19448.1 - 0.033 14.2 0.4 0.056 13.4 0.4 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Nfu_N PF08712.11 EGO19449.1 - 2.2e-29 101.4 0.0 1.2e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGO19449.1 - 3e-26 91.4 0.1 5.3e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EGO19449.1 - 0.083 13.0 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus B12D PF06522.11 EGO19449.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MINDY_DUB PF04424.13 EGO19451.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 MINDY deubiquitinase PUF PF00806.19 EGO19452.1 - 1.9e-59 194.1 11.8 7.8e-08 31.6 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RA PF00788.23 EGO19452.1 - 0.18 12.5 0.4 2 9.1 0.1 2.4 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Atg14 PF10186.9 EGO19453.1 - 2.1e-13 50.1 0.2 4.8e-13 48.9 0.2 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Protocadherin PF08374.11 EGO19453.1 - 0.028 14.4 2.9 0.35 10.8 0.9 2.2 2 0 0 2 2 2 0 Protocadherin DUF3450 PF11932.8 EGO19453.1 - 0.21 10.8 1.8 0.34 10.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cullin PF00888.22 EGO19455.1 - 4.4e-06 25.6 0.0 5.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Phage_Mu_F PF04233.14 EGO19455.1 - 0.046 14.5 0.1 0.079 13.7 0.1 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein TRAPP PF04051.16 EGO19457.1 - 3.7e-43 146.8 0.0 4.4e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DHO_dh PF01180.21 EGO19458.1 - 8.3e-16 58.0 0.0 3.7e-15 55.9 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase HMG_box PF00505.19 EGO19459.1 - 3.3e-11 43.4 0.1 5.3e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO19459.1 - 0.022 15.4 0.1 0.064 13.9 0.0 1.8 2 0 0 2 2 2 0 HMG-box domain NETI PF14044.6 EGO19459.1 - 0.21 11.3 0.5 0.41 10.4 0.5 1.4 1 0 0 1 1 1 0 NETI protein Cortexin PF11057.8 EGO19460.1 - 0.14 12.0 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 Cortexin of kidney Shisa PF13908.6 EGO19460.1 - 0.27 11.5 0.9 0.33 11.2 0.3 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PARP PF00644.20 EGO19461.1 - 3.5e-53 180.1 1.2 3e-52 177.1 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGO19461.1 - 1.3e-37 128.9 0.0 2.1e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGO19461.1 - 2.6e-21 75.5 0.1 6.6e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 WGR domain RdRP PF05183.12 EGO19462.1 - 2.4e-74 251.0 0.0 2.9e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 EGO19463.1 - 4.7e-87 293.0 0.0 8e-83 279.0 0.0 3.1 1 1 0 1 1 1 1 RNA dependent RNA polymerase Myc_N PF01056.18 EGO19463.1 - 0.28 11.1 3.6 0.47 10.3 3.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 EGO19463.1 - 0.47 8.5 15.4 0.68 8.0 15.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EGO19463.1 - 0.69 10.0 11.8 1.1 9.3 11.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Chromo_2 PF18704.1 EGO19463.1 - 2.3 8.6 5.6 11 6.3 5.6 2.1 1 1 0 1 1 1 0 Chromatin organization modifier domain 2 DUF2722 PF10846.8 EGO19463.1 - 2.5 7.0 4.8 3.7 6.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.12 EGO19463.1 - 2.6 7.3 13.1 4 6.7 13.1 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EGO19463.1 - 3 6.0 13.2 4.3 5.4 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 EGO19463.1 - 3.5 7.5 13.7 5.5 6.9 13.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EGO19463.1 - 4.4 5.5 12.2 5.2 5.2 9.4 2.1 3 0 0 3 3 3 0 CDC45-like protein CobT PF06213.12 EGO19463.1 - 4.5 6.6 11.4 6.8 6.0 11.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 EGO19463.1 - 4.6 7.2 9.2 8.7 6.3 9.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 EGO19463.1 - 5.9 6.2 12.4 8.4 5.7 12.4 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 EGO19463.1 - 8.7 5.8 11.5 14 5.2 11.5 1.2 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 EGO19463.1 - 9.1 5.3 18.8 14 4.7 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NAD_binding_8 PF13450.6 EGO19464.1 - 2.7e-13 49.9 0.0 6.3e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGO19464.1 - 0.00049 19.5 0.0 0.48 9.7 0.0 2.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGO19464.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO19464.1 - 0.013 14.6 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGO19464.1 - 0.032 13.5 0.2 0.076 12.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EGO19464.1 - 0.065 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGO19464.1 - 0.17 11.9 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGO19464.1 - 0.18 11.0 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UMP1 PF05348.11 EGO19465.1 - 5e-36 123.5 0.1 6.3e-36 123.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF4120 PF13496.6 EGO19465.1 - 0.058 13.8 0.0 0.086 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) SPRY PF00622.28 EGO19466.1 - 3.9e-23 81.8 0.2 6.2e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 EGO19466.1 - 2.6e-17 63.1 0.0 3.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGO19466.1 - 4.8e-05 23.2 0.3 0.00022 21.0 0.1 2.1 2 0 0 2 2 2 1 LisH Fe-S_biosyn PF01521.20 EGO19467.1 - 1.4e-20 73.6 0.0 1.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SET PF00856.28 EGO19468.1 - 1.5e-13 51.5 0.1 4.8e-12 46.6 0.1 2.3 1 1 0 1 1 1 1 SET domain Fibrillin_U_N PF18193.1 EGO19468.1 - 0.083 13.0 0.4 0.3 11.2 0.4 1.9 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain SBDS PF01172.18 EGO19469.1 - 1.8e-35 120.9 2.0 2.9e-35 120.2 2.0 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EGO19469.1 - 9.6e-34 115.9 0.2 2e-33 114.9 0.0 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain NmrA PF05368.13 EGO19470.1 - 4.1e-16 59.2 0.0 5.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO19470.1 - 5.4e-09 36.2 0.1 1e-07 32.1 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO19470.1 - 0.0019 17.7 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ABC_tran PF00005.27 EGO19471.1 - 8.8e-45 152.6 0.0 6.3e-21 75.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGO19471.1 - 1.8e-22 79.1 3.3 1.8e-22 79.1 3.3 2.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EGO19471.1 - 6.3e-15 55.8 16.5 0.00034 20.5 0.1 4.6 3 2 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EGO19471.1 - 3.9e-08 33.9 0.5 0.024 15.2 0.0 4.5 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.19 EGO19471.1 - 4.7e-08 32.7 0.5 0.032 13.7 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO19471.1 - 1.2e-07 31.8 0.1 0.006 16.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGO19471.1 - 1.5e-06 28.6 0.4 0.052 13.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGO19471.1 - 1.5e-06 28.2 0.0 0.064 13.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGO19471.1 - 1.8e-06 27.6 0.3 0.061 13.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EGO19471.1 - 3.2e-06 27.2 0.0 0.082 12.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 EGO19471.1 - 1.2e-05 24.5 0.1 0.01 14.8 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGO19471.1 - 1.6e-05 25.3 2.5 0.12 12.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EGO19471.1 - 2.4e-05 24.7 0.3 0.083 13.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EGO19471.1 - 0.00036 20.7 0.2 0.44 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EGO19471.1 - 0.0016 18.2 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGO19471.1 - 0.0026 18.1 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 EGO19471.1 - 0.0029 18.0 0.0 2.6 8.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EGO19471.1 - 0.0042 17.2 0.3 1.5 8.9 0.0 3.0 3 1 0 3 3 2 1 Dynamin family AAA_30 PF13604.6 EGO19471.1 - 0.0058 16.4 1.2 1.1 8.9 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EGO19471.1 - 0.0059 17.1 17.3 0.19 12.2 0.0 4.8 5 0 0 5 5 5 2 AAA domain Roc PF08477.13 EGO19471.1 - 0.0082 16.4 0.0 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EGO19471.1 - 0.0086 16.0 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 NTPase DUF87 PF01935.17 EGO19471.1 - 0.012 15.8 0.1 0.012 15.8 0.1 3.7 4 2 1 5 5 4 0 Helicase HerA, central domain DUF815 PF05673.13 EGO19471.1 - 0.012 14.8 0.0 0.51 9.5 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EGO19471.1 - 0.013 14.7 0.0 3.6 6.7 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 EGO19471.1 - 0.013 15.5 0.0 10 6.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGO19471.1 - 0.022 14.8 0.1 5.2 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGO19471.1 - 0.027 14.0 0.0 8.4 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 EGO19471.1 - 0.031 13.5 0.6 0.25 10.5 0.0 2.7 4 0 0 4 4 4 0 KAP family P-loop domain cobW PF02492.19 EGO19471.1 - 0.033 13.8 0.0 9.5 5.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 EGO19471.1 - 0.049 13.5 0.6 0.61 9.9 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 EGO19471.1 - 0.053 13.4 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 EGO19471.1 - 0.07 12.4 0.1 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EGO19471.1 - 0.091 12.3 2.1 11 5.5 0.0 3.6 5 0 0 5 5 4 0 AAA domain PduV-EutP PF10662.9 EGO19471.1 - 0.14 11.9 0.0 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGO19471.1 - 0.14 12.2 0.1 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EGO19471.1 - 0.16 11.7 0.0 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Agglutinin_C PF18021.1 EGO19471.1 - 0.29 11.7 1.9 2.3 8.8 0.5 2.4 2 0 0 2 2 2 0 Agglutinin C-terminal SbcCD_C PF13558.6 EGO19471.1 - 0.33 11.2 3.7 2.6 8.3 0.2 3.7 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EGO19471.1 - 1.5 8.5 16.0 0.7 9.5 0.1 4.3 5 1 0 5 5 5 0 AAA ATPase domain DNA_topoisoIV PF00521.20 EGO19472.1 - 4.5e-128 427.8 0.2 4.5e-128 427.8 0.2 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGO19472.1 - 2.1e-51 173.5 1.0 2.1e-51 173.5 1.0 2.9 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGO19472.1 - 1.8e-29 102.4 2.5 4.4e-29 101.2 2.5 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGO19472.1 - 8.2e-13 48.8 0.1 2.4e-12 47.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGO19472.1 - 3.7e-06 27.1 0.0 1.7e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Ntox17 PF15524.6 EGO19472.1 - 0.047 14.0 1.2 0.16 12.3 0.2 2.4 2 0 0 2 2 2 0 Novel toxin 17 DUF1146 PF06612.11 EGO19472.1 - 0.25 11.4 0.1 0.67 10.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) SpoIIID PF12116.8 EGO19473.1 - 0.029 14.5 0.1 0.056 13.5 0.1 1.4 1 1 0 1 1 1 0 Stage III sporulation protein D Oxysterol_BP PF01237.18 EGO19474.1 - 2e-85 286.9 0.1 3e-83 279.7 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DEAD PF00270.29 EGO19475.1 - 1e-46 158.9 0.0 1.9e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO19475.1 - 1.8e-31 108.8 0.0 5.6e-28 97.5 0.0 3.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EGO19475.1 - 0.036 13.4 0.0 0.036 13.4 0.0 2.9 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EGO19475.1 - 0.75 8.9 0.0 0.75 8.9 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Vfa1 PF08432.10 EGO19475.1 - 3.5 7.9 16.6 5.8 7.2 16.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MCM_bind PF09739.9 EGO19475.1 - 4.1 5.7 8.0 5.7 5.3 8.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DOT1 PF08123.13 EGO19477.1 - 9.3e-64 214.7 0.0 1.2e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 EGO19477.1 - 0.063 13.9 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGO19477.1 - 0.22 10.8 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Actin PF00022.19 EGO19478.1 - 8.9e-47 159.6 0.0 1e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 Actin Ras PF00071.22 EGO19479.1 - 2.8e-64 215.6 0.0 3.3e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO19479.1 - 6.6e-34 116.7 0.1 1.1e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO19479.1 - 3.7e-14 52.6 0.1 4.8e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO19479.1 - 7.8e-06 25.6 0.1 1.8e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO19479.1 - 9.2e-05 21.9 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGO19479.1 - 0.00012 22.1 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO19479.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO19479.1 - 0.011 16.2 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EGO19479.1 - 0.021 14.4 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 EGO19479.1 - 0.043 13.6 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 EGO19479.1 - 0.057 12.8 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGO19479.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 EGO19479.1 - 0.085 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin MCM PF00493.23 EGO19479.1 - 0.14 11.3 0.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 EGO19480.1 - 4.5e-26 92.0 0.0 1.3e-25 90.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO19480.1 - 8.1e-07 29.1 1.7 0.0017 18.3 0.3 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO19480.1 - 0.00065 19.2 0.0 0.057 12.9 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO19480.1 - 0.00093 19.8 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGO19480.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGO19480.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 EGO19480.1 - 0.0025 18.0 0.6 0.0056 16.9 0.0 1.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EGO19480.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO19480.1 - 0.018 15.4 0.0 0.067 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 EGO19480.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO19480.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Nic96 PF04097.14 EGO19481.1 - 3.9e-153 511.2 0.0 5e-153 510.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Thiolase_N PF00108.23 EGO19486.1 - 8.9e-16 58.0 0.0 1.4e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO19486.1 - 1.2e-06 28.2 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO19486.1 - 1.5e-05 24.7 0.9 0.0036 16.9 0.1 2.5 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGO19486.1 - 8e-05 22.4 0.2 0.0039 17.0 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 EGO19486.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Med9 PF07544.13 EGO19487.1 - 7.9e-06 25.9 0.4 2e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_3 PF13758.6 EGO19487.1 - 0.084 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit Pkinase PF00069.25 EGO19488.1 - 6.8e-43 146.9 0.0 7.5e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19488.1 - 1.5e-17 63.8 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO19488.1 - 0.00037 19.9 0.0 0.00078 18.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGO19488.1 - 0.055 13.4 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_2 PF13923.6 EGO19489.1 - 6.2e-08 32.4 6.2 6.2e-08 32.4 6.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO19489.1 - 2.7e-06 27.6 11.0 4.2e-06 27.0 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO19489.1 - 3.6e-06 26.7 9.4 5.9e-06 26.1 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO19489.1 - 1.7e-05 24.6 10.6 2.8e-05 23.9 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO19489.1 - 5.4e-05 23.1 6.3 0.0002 21.3 6.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO19489.1 - 0.003 17.7 8.6 0.006 16.7 8.6 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGO19489.1 - 0.0042 17.0 9.0 0.016 15.2 2.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO19489.1 - 0.011 15.6 5.1 0.011 15.6 5.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGO19489.1 - 0.013 15.5 4.1 0.024 14.7 4.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PRIMA1 PF16101.5 EGO19489.1 - 0.038 14.0 1.6 0.067 13.2 1.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-rbx1 PF12678.7 EGO19489.1 - 0.31 11.4 10.5 0.18 12.1 5.0 2.5 1 1 2 3 3 3 0 RING-H2 zinc finger domain CAP_N PF01213.19 EGO19489.1 - 6.9 6.0 9.2 13 5.1 9.2 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Plavaka PF18759.1 EGO19490.1 - 2.3e-53 181.5 0.0 4.1e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Drf_FH1 PF06346.12 EGO19491.1 - 0.039 13.7 11.3 0.046 13.4 8.2 2.0 2 0 0 2 2 2 0 Formin Homology Region 1 YL1 PF05764.13 EGO19491.1 - 2.9 7.9 9.0 5.2 7.1 9.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FAD_binding_3 PF01494.19 EGO19493.1 - 7.4e-20 71.5 2.6 6.5e-18 65.1 2.6 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO19493.1 - 1.6e-07 31.4 2.1 4e-07 30.2 2.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO19493.1 - 1.9e-06 27.4 0.6 4e-05 23.0 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO19493.1 - 4.6e-05 23.9 1.1 9.4e-05 22.9 1.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO19493.1 - 0.00065 18.5 2.8 0.00095 18.0 2.8 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGO19493.1 - 0.0011 18.6 3.8 0.0018 17.9 3.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO19493.1 - 0.0012 17.8 0.6 0.0063 15.4 0.5 1.9 2 0 0 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.18 EGO19493.1 - 0.0091 15.9 2.3 0.016 15.1 2.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EGO19493.1 - 0.018 14.3 0.9 0.03 13.6 0.9 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EGO19493.1 - 0.023 13.8 1.7 0.037 13.1 1.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EGO19493.1 - 0.038 13.3 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 EGO19493.1 - 0.04 13.0 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase UDPG_MGDP_dh_N PF03721.14 EGO19493.1 - 0.08 12.5 0.6 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EGO19493.1 - 0.21 11.2 0.8 0.41 10.3 0.8 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EGO19493.1 - 0.3 10.1 4.5 0.63 9.0 3.8 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EGO19493.1 - 0.35 10.1 0.6 0.53 9.5 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 EGO19494.1 - 6.1e-06 26.0 2.6 2.2e-05 24.2 2.6 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EGO19494.1 - 0.03 14.2 0.3 7.9 6.5 0.0 3.3 3 0 0 3 3 3 0 F-box domain Ribosomal_S14 PF00253.21 EGO19495.1 - 1.7e-14 53.3 3.5 1.8e-14 53.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Porphobil_deam PF01379.20 EGO19496.1 - 8.6e-72 240.9 0.0 1.2e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGO19496.1 - 3.9e-17 62.4 0.7 9.2e-17 61.2 0.7 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UQ_con PF00179.26 EGO19497.1 - 6.3e-28 97.2 0.0 7.6e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO19497.1 - 0.00062 19.5 0.0 0.027 14.2 0.1 2.0 1 1 1 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 EGO19497.1 - 0.02 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain ArsA_ATPase PF02374.15 EGO19498.1 - 7.5e-112 373.4 1.1 8.7e-112 373.2 1.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGO19498.1 - 1.2e-13 51.4 0.1 5.3e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EGO19498.1 - 1.4e-12 47.8 0.0 3.5e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EGO19498.1 - 6.1e-06 25.9 0.0 4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGO19498.1 - 2.5e-05 23.9 0.1 7.2e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EGO19498.1 - 6.2e-05 22.6 4.1 0.00014 21.4 0.6 2.8 2 2 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EGO19498.1 - 0.00011 22.0 0.5 0.0022 17.7 0.1 2.5 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EGO19498.1 - 0.014 15.0 1.8 0.073 12.6 0.6 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO19498.1 - 0.026 14.2 0.0 0.081 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 EGO19498.1 - 0.041 13.2 0.1 0.11 11.8 0.1 1.7 1 1 0 1 1 1 0 VirC1 protein PhoH PF02562.16 EGO19498.1 - 0.086 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein SRP68 PF16969.5 EGO19499.1 - 8.6e-82 275.9 9.1 7.1e-81 272.9 3.5 2.1 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 Ku PF02735.16 EGO19500.1 - 1.6e-27 96.5 0.1 3.2e-27 95.6 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EGO19500.1 - 8.1e-27 93.7 0.0 1.5e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.28 EGO19500.1 - 0.0004 20.7 0.0 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 EGO19500.1 - 0.0033 18.1 0.2 0.0033 18.1 0.2 2.4 2 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm SNF2_N PF00176.23 EGO19501.1 - 5.7e-70 235.8 0.3 1.3e-69 234.6 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EGO19501.1 - 8.3e-18 64.2 0.0 2.5e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EGO19501.1 - 6.1e-17 61.7 7.5 6.1e-17 61.7 7.5 2.9 2 0 0 2 2 2 1 HSA QLQ PF08880.11 EGO19501.1 - 2.6e-13 49.5 0.1 6.9e-13 48.1 0.1 1.8 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 EGO19501.1 - 3.3e-12 46.8 0.6 3.3e-12 46.8 0.6 3.6 5 0 0 5 5 2 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.31 EGO19501.1 - 4e-12 46.5 0.6 2.3e-11 44.0 0.1 2.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO19501.1 - 6.1e-07 29.6 0.0 6.1e-07 29.6 0.0 2.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit PriA_3primeBD PF17764.1 EGO19501.1 - 0.11 12.4 0.1 0.53 10.2 0.1 2.1 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) AAA_22 PF13401.6 EGO19501.1 - 0.21 11.9 3.2 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain DBINO PF13892.6 EGO19501.1 - 0.35 11.2 9.7 1.5 9.1 9.7 2.2 1 0 0 1 1 1 0 DNA-binding domain NADPH_Ox PF08414.10 EGO19501.1 - 4.4 7.7 5.3 1.1 9.6 0.9 2.2 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase bZIP_1 PF00170.21 EGO19503.1 - 2.9e-12 46.5 15.8 4.8e-12 45.8 15.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO19503.1 - 4.7e-05 23.4 15.5 4.7e-05 23.4 15.5 1.9 1 1 1 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 EGO19503.1 - 0.00035 20.3 1.4 0.0007 19.3 1.4 1.5 1 0 0 1 1 1 1 Septum formation initiator INCA1 PF15142.6 EGO19503.1 - 0.016 15.2 0.6 0.039 14.0 0.6 1.6 1 0 0 1 1 1 0 INCA1 SHE3 PF17078.5 EGO19503.1 - 0.069 12.9 12.4 0.037 13.7 9.7 1.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 YqgF PF14639.6 EGO19503.1 - 0.07 12.9 1.1 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 YabA PF06156.13 EGO19503.1 - 0.11 13.1 0.4 0.24 12.1 0.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 EGO19503.1 - 0.15 12.4 3.7 0.47 10.8 3.7 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family KASH_CCD PF14662.6 EGO19503.1 - 0.23 11.3 9.4 0.38 10.5 9.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 EGO19503.1 - 0.27 11.1 3.1 0.66 9.9 3.1 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor V_ATPase_I PF01496.19 EGO19503.1 - 0.3 9.0 1.7 0.44 8.4 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.9 EGO19503.1 - 0.69 10.2 5.5 1.3 9.2 5.5 1.4 1 0 0 1 1 1 0 Haemolysin XhlA GvpL_GvpF PF06386.11 EGO19503.1 - 1.9 8.4 4.8 3.5 7.5 4.8 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ABC_tran_Xtn PF12848.7 EGO19503.1 - 2.2 8.4 7.7 4.1 7.5 7.7 1.4 1 0 0 1 1 1 0 ABC transporter bZIP_Maf PF03131.17 EGO19503.1 - 5.4 7.6 12.4 11 6.6 12.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Erf4 PF10256.9 EGO19506.1 - 1.1e-34 119.0 0.2 1.3e-34 118.7 0.2 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family 4F5 PF04419.14 EGO19509.1 - 7.7e-07 29.9 12.3 7.7e-07 29.9 12.3 2.4 2 1 0 2 2 2 1 4F5 protein family Brr6_like_C_C PF10104.9 EGO19510.1 - 4e-45 152.9 0.4 5.2e-45 152.5 0.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CLP_protease PF00574.23 EGO19511.1 - 1.9e-74 249.5 0.0 2.4e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease SAP30_Sin3_bdg PF13867.6 EGO19513.1 - 0.0063 16.8 0.2 0.22 11.9 0.1 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Utp21 PF04192.12 EGO19513.1 - 0.24 10.9 0.0 0.24 10.9 0.0 1.4 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Chorismate_synt PF01264.21 EGO19514.1 - 2.8e-137 456.8 0.0 3.2e-137 456.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase STE3 PF02076.15 EGO19515.1 - 4.8e-100 334.5 20.3 5.6e-100 334.3 20.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4027 PF13219.6 EGO19515.1 - 0.092 12.6 0.5 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) DUF3810 PF12725.7 EGO19515.1 - 5.5 6.3 8.9 0.15 11.4 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) GST_N_3 PF13417.6 EGO19518.1 - 4.5e-12 46.2 0.1 7.3e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO19518.1 - 8.3e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGO19518.1 - 2.9e-06 27.5 0.1 8.8e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO19518.1 - 0.0003 20.7 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGO19518.1 - 0.00092 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 EGO19518.1 - 0.0079 16.4 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO19518.1 - 0.036 14.3 0.0 0.51 10.6 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain PknG_TPR PF16918.5 EGO19518.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat UPF0052 PF01933.18 EGO19519.1 - 2.1e-49 168.4 0.0 2.9e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Glycos_transf_2 PF00535.26 EGO19521.1 - 2.7e-32 111.9 0.0 3.3e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGO19521.1 - 4e-14 53.1 0.0 5.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGO19521.1 - 8.3e-05 22.2 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 EGO19521.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 LSM PF01423.22 EGO19522.1 - 2.2e-11 43.3 0.0 2.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sel1 PF08238.12 EGO19523.1 - 1.3e-13 51.1 3.7 0.00041 20.9 0.5 4.0 4 0 0 4 4 4 3 Sel1 repeat HA2 PF04408.23 EGO19525.1 - 8.3e-23 80.7 0.0 2.5e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO19525.1 - 1.4e-14 54.2 0.0 3.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO19525.1 - 7.3e-14 52.0 0.0 1.6e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO19525.1 - 0.004 16.9 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Plavaka PF18759.1 EGO19527.1 - 1.4e-42 146.1 0.0 2.8e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase Smg4_UPF3 PF03467.15 EGO19527.1 - 0.19 11.7 5.9 0.35 10.9 5.9 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family DUF1848 PF08902.11 EGO19528.1 - 0.23 11.1 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Calpain_u2 PF16648.5 EGO19529.1 - 0.096 13.2 0.5 0.096 13.2 0.5 2.3 3 0 0 3 3 3 0 Unstructured region on Calpain-3 Abhydrolase_1 PF00561.20 EGO19530.1 - 7.1e-21 75.0 0.1 2.5e-20 73.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO19530.1 - 6.2e-17 62.9 1.1 8.5e-17 62.5 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO19530.1 - 9.8e-08 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 EGO19530.1 - 0.001 18.0 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Ndr PF03096.14 EGO19530.1 - 0.0041 15.9 0.0 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family PBP PF01161.20 EGO19532.1 - 4.6e-15 56.1 0.2 9.7e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3972 PF13118.6 EGO19532.1 - 0.051 14.0 1.2 0.11 13.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) TRAF_BIRC3_bd PF16673.5 EGO19532.1 - 0.14 11.9 1.4 0.28 11.0 1.4 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Alpha_kinase PF02816.18 EGO19533.1 - 0.001 19.2 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Abhydrolase_1 PF00561.20 EGO19536.1 - 1.2e-20 74.2 0.1 3.2e-20 72.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO19536.1 - 1.2e-15 58.8 1.8 1.7e-15 58.3 1.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO19536.1 - 2.6e-07 30.2 0.0 4.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 EGO19536.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Ndr PF03096.14 EGO19536.1 - 0.022 13.5 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.11 EGO19536.1 - 0.065 12.2 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase FYVE PF01363.21 EGO19537.1 - 5.7e-17 61.6 3.4 5.7e-17 61.6 3.4 1.9 3 0 0 3 3 3 1 FYVE zinc finger IBR PF01485.21 EGO19537.1 - 0.12 12.6 4.6 0.35 11.1 4.6 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PHD PF00628.29 EGO19540.1 - 3.4e-11 42.8 7.8 5.7e-11 42.1 7.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGO19540.1 - 0.0076 15.8 3.5 0.014 14.9 3.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EGO19540.1 - 0.0084 15.8 1.5 0.016 14.9 1.5 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EGO19540.1 - 0.054 13.6 6.4 0.11 12.6 6.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 EGO19540.1 - 0.27 11.3 4.2 0.62 10.1 4.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Prok-RING_1 PF14446.6 EGO19540.1 - 0.36 10.8 7.0 0.074 13.0 3.5 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_methylase PF00145.17 EGO19541.1 - 1.4e-27 97.0 0.0 3.8e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Thiolase_N PF00108.23 EGO19542.1 - 2.9e-14 53.0 0.0 5.2e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO19542.1 - 8.5e-07 28.7 0.0 3.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO19542.1 - 2.3e-05 24.1 0.5 0.0065 16.1 0.1 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGO19542.1 - 5.9e-05 22.8 0.0 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SMN PF06003.12 EGO19543.1 - 0.035 13.4 13.7 0.05 12.8 1.3 3.1 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) Ank_4 PF13637.6 EGO19544.1 - 6.6e-05 23.4 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO19544.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGO19544.1 - 0.0002 21.9 0.0 0.00025 21.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO19544.1 - 0.00034 20.9 0.0 0.00081 19.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGO19544.1 - 0.0008 19.7 0.1 0.0013 19.0 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2179 PF10035.9 EGO19545.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Ank_2 PF12796.7 EGO19547.1 - 1.1e-22 80.4 0.0 1.4e-11 44.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO19547.1 - 3.4e-21 75.0 0.7 9.1e-09 35.4 0.3 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EGO19547.1 - 2.9e-18 65.4 0.3 2.1e-06 27.9 0.3 5.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGO19547.1 - 1.4e-17 63.8 0.2 3e-05 24.5 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO19547.1 - 1.8e-10 40.1 1.2 0.0011 19.2 0.2 5.5 6 1 0 6 6 6 2 Ankyrin repeat RSD-2 PF07547.13 EGO19547.1 - 0.12 12.9 0.1 5.4 7.6 0.0 2.4 2 1 0 2 2 2 0 RSD-2 N-terminal domain ERGIC_N PF13850.6 EGO19552.1 - 1.9 8.9 6.8 8 6.9 0.2 3.2 3 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pex14_N PF04695.13 EGO19554.1 - 0.2 12.3 11.3 0.22 12.2 11.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDE_Tnp_4 PF13359.6 EGO19555.1 - 1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO19555.1 - 0.00086 19.0 0.0 0.0069 16.1 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain RbsD_FucU PF05025.13 EGO19558.1 - 0.02 15.3 0.4 0.044 14.2 0.4 1.5 1 0 0 1 1 1 0 RbsD / FucU transport protein family Gram_pos_anchor PF00746.21 EGO19561.1 - 2.4 8.2 4.9 1.3 9.0 1.3 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RTA1 PF04479.13 EGO19562.1 - 5.2e-59 199.3 3.8 5.2e-59 199.3 3.8 1.3 2 0 0 2 2 2 1 RTA1 like protein DHFR_1 PF00186.19 EGO19563.1 - 9e-32 110.0 0.0 1.3e-31 109.4 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase Herpes_U30 PF04523.13 EGO19567.1 - 0.082 10.8 0.0 0.1 10.5 0.0 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Myb_DNA-bind_3 PF12776.7 EGO19568.1 - 0.0064 17.5 0.4 0.033 15.2 0.2 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SepF PF04472.12 EGO19569.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Cell division protein SepF DUF4111 PF13427.6 EGO19569.1 - 0.036 14.2 0.2 0.22 11.7 0.0 2.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4111) TNFR_16_TM PF18422.1 EGO19570.1 - 0.0055 16.6 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain Syndecan PF01034.20 EGO19570.1 - 0.067 13.1 0.3 0.067 13.1 0.3 1.7 2 0 0 2 2 2 0 Syndecan domain F-box-like PF12937.7 EGO19571.1 - 3.9e-09 36.3 0.8 1.1e-08 34.8 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EGO19571.1 - 0.037 14.0 0.1 0.14 12.2 0.1 2.0 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 EGO19572.1 - 2.9e-07 30.2 0.9 9.4e-07 28.6 0.9 2.0 1 0 0 1 1 1 1 F-box-like Invas_SpaK PF03519.14 EGO19572.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Invasion protein B family F-box PF00646.33 EGO19572.1 - 8.9 6.3 7.6 1.5 8.8 0.7 3.3 3 1 0 3 3 3 0 F-box domain PCI PF01399.27 EGO19573.1 - 4.4e-06 27.1 0.9 2.1e-05 25.0 0.9 2.1 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EGO19573.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Rgp1 PF08737.10 EGO19574.1 - 7.4e-51 173.6 0.0 1.3e-50 172.8 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EGO19574.1 - 0.0015 18.6 0.0 0.18 11.9 0.0 3.0 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGO19574.1 - 0.011 16.2 0.0 5.9 7.4 0.0 3.4 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain PSP1 PF04468.12 EGO19575.1 - 8.5e-31 106.1 1.8 1.3e-30 105.5 1.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-ANAPC11 PF12861.7 EGO19576.1 - 1.3e-40 137.3 10.1 1.6e-40 137.0 10.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGO19576.1 - 1.6e-21 76.3 11.2 2.5e-21 75.7 11.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO19576.1 - 0.00019 21.7 16.3 0.0031 17.8 16.3 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO19576.1 - 0.0016 18.3 2.2 0.0016 18.3 2.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO19576.1 - 0.072 13.1 10.4 0.16 12.0 10.4 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGO19576.1 - 0.16 11.9 13.0 1.4 8.9 13.4 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO19576.1 - 0.18 11.7 13.5 0.95 9.4 13.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGO19576.1 - 1.4 8.6 20.4 0.54 9.9 13.5 2.7 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGO19576.1 - 4.7 7.1 13.9 22 4.9 13.9 2.1 1 1 0 1 1 1 0 RING-like zinc finger Retrotran_gag_2 PF14223.6 EGO19579.1 - 3.2e-09 36.6 0.0 4.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO19579.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF5314 PF17241.2 EGO19579.1 - 0.058 13.1 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5314) Helicase_C PF00271.31 EGO19583.1 - 3.3e-09 37.1 0.0 4.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGO19583.1 - 0.00069 18.9 0.0 0.00079 18.7 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_18 PF13238.6 EGO19584.1 - 0.001 19.6 0.1 0.017 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO19584.1 - 0.016 15.6 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGO19584.1 - 0.031 14.4 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGO19584.1 - 0.05 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EGO19584.1 - 0.15 12.1 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGO19584.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain GST_N_2 PF13409.6 EGO19585.1 - 7.4e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO19585.1 - 1.8e-07 31.5 0.0 1.1e-06 28.9 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO19585.1 - 4.3e-05 23.6 0.1 8.6e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO19585.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO19585.1 - 0.0077 16.2 0.2 0.019 15.0 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4538 PF15061.6 EGO19585.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) GST_N PF02798.20 EGO19585.1 - 0.07 13.5 0.0 0.82 10.1 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MCPVI PF02993.14 EGO19586.1 - 6.4 6.5 6.4 8.7 6.1 6.4 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Bromodomain PF00439.25 EGO19587.1 - 2.4e-23 82.0 0.0 1.4e-14 53.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EGO19587.1 - 3.5e-09 36.6 0.0 7.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain TFIIF_alpha PF05793.12 EGO19588.1 - 0.018 13.6 17.5 0.019 13.6 17.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCDC106 PF15794.5 EGO19588.1 - 0.051 13.3 9.6 0.059 13.1 9.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4196 PF13846.6 EGO19588.1 - 0.18 12.0 13.7 0.25 11.5 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) PGA2 PF07543.12 EGO19588.1 - 0.26 11.3 8.3 0.32 11.0 8.3 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Sigma70_ner PF04546.13 EGO19588.1 - 0.77 9.6 8.9 0.89 9.4 8.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 EGO19588.1 - 1.1 8.6 9.4 1.2 8.5 9.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 EGO19588.1 - 1.4 6.9 10.8 1.6 6.7 10.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 EGO19588.1 - 7.1 4.8 15.1 8.5 4.5 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein UPF0239 PF06783.11 EGO19588.1 - 7.7 6.8 9.1 14 5.9 9.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Chs7 PF12271.8 EGO19589.1 - 3e-116 387.8 20.2 3.4e-116 387.6 20.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MerC PF03203.14 EGO19589.1 - 5.9 7.4 12.5 0.23 11.9 2.1 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein A_deaminase PF00962.22 EGO19590.1 - 5.3e-21 75.3 0.0 1.7e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase adh_short_C2 PF13561.6 EGO19591.1 - 4.7e-49 167.1 7.4 6.2e-41 140.5 4.6 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO19591.1 - 2.3e-46 157.7 4.3 2.9e-46 157.4 4.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO19591.1 - 1e-14 54.9 0.7 1.5e-14 54.3 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGO19591.1 - 0.23 11.3 1.4 0.43 10.4 1.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spore_II_R PF09551.10 EGO19592.1 - 0.033 14.6 2.3 0.054 14.0 2.3 1.4 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) CcdA PF07362.12 EGO19592.1 - 2.2 8.8 9.1 4.5 7.8 2.8 2.4 1 1 1 2 2 2 0 Post-segregation antitoxin CcdA Hamartin PF04388.12 EGO19594.1 - 0.013 14.2 2.6 0.016 13.9 2.6 1.0 1 0 0 1 1 1 0 Hamartin protein Rtf2 PF04641.12 EGO19598.1 - 9.1e-74 248.1 0.2 1.1e-73 247.9 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EGO19598.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EGO19598.1 - 0.023 14.5 1.0 0.28 11.0 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGO19598.1 - 0.033 14.2 1.3 0.17 11.9 0.0 2.7 3 0 0 3 3 3 0 RING-type zinc-finger zf-UDP PF14569.6 EGO19598.1 - 0.36 11.0 2.5 0.55 10.4 0.6 2.4 2 1 0 2 2 2 0 Zinc-binding RING-finger MMR_HSR1 PF01926.23 EGO19599.1 - 6.7e-10 39.1 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO19599.1 - 8.3e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 EGO19599.1 - 2.6e-05 23.9 0.0 0.0002 21.0 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGO19599.1 - 0.00017 21.8 0.1 0.0004 20.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGO19599.1 - 0.00019 21.5 0.4 0.00049 20.2 0.3 1.6 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 EGO19599.1 - 0.00082 19.8 0.0 0.0066 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 EGO19599.1 - 0.0037 16.7 0.1 0.0097 15.3 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 EGO19599.1 - 0.004 17.7 0.0 0.0082 16.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 EGO19599.1 - 0.0082 15.5 0.0 0.075 12.4 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EGO19599.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 EGO19599.1 - 0.02 14.1 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IIGP PF05049.13 EGO19599.1 - 0.037 13.1 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EGO19599.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO19599.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO19599.1 - 0.21 12.1 0.0 0.38 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGO19600.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO19600.1 - 5.9e-06 25.8 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EGO19600.1 - 0.0026 18.0 0.0 0.0083 16.3 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGO19600.1 - 0.0093 16.4 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGO19600.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGO19600.1 - 0.027 15.0 0.0 0.069 13.7 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EGO19600.1 - 0.034 14.2 0.7 0.11 12.6 0.1 2.1 3 0 0 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 EGO19600.1 - 0.036 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 EGO19600.1 - 0.039 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 EGO19600.1 - 0.045 13.9 0.1 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 EGO19600.1 - 0.045 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO19600.1 - 0.047 14.0 0.0 0.092 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 EGO19600.1 - 0.064 12.9 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 Ras family Gtr1_RagA PF04670.12 EGO19600.1 - 0.083 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Zeta_toxin PF06414.12 EGO19600.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EGO19600.1 - 0.14 12.7 1.6 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.15 EGO19601.1 - 3.3e-72 242.2 0.0 9.3e-70 234.2 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase OPT PF03169.15 EGO19602.1 - 2e-186 621.3 66.4 2.3e-186 621.1 66.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydrophobin PF01185.18 EGO19603.1 - 5.1e-23 81.5 9.3 6.2e-23 81.2 9.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EGO19604.1 - 5.1e-23 81.5 9.3 6.2e-23 81.2 9.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin ChaC PF04752.12 EGO19605.1 - 2.7e-52 177.4 0.0 3.1e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF21 PF01595.20 EGO19606.1 - 1.7e-30 106.1 0.2 2.8e-30 105.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGO19606.1 - 0.0001 22.7 0.3 0.42 11.1 0.0 3.2 3 0 0 3 3 3 2 CBS domain tRNA_U5-meth_tr PF05958.11 EGO19607.1 - 1.4e-15 57.2 0.0 5.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EGO19607.1 - 1e-05 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EGO19607.1 - 7.6e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGO19607.1 - 0.00075 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EGO19607.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGO19607.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGO19607.1 - 0.02 15.5 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_4 PF01063.19 EGO19608.1 - 3.8e-29 102.1 0.0 4.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Alpha-amylase PF00128.24 EGO19609.1 - 1.2e-58 199.3 0.2 1.4e-57 195.8 0.2 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EGO19609.1 - 1.8e-09 37.8 1.4 3.1e-09 37.0 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) adh_short PF00106.25 EGO19610.1 - 8e-10 38.5 0.3 1.1e-09 38.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO19610.1 - 0.0012 18.5 0.2 0.0015 18.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 EGO19610.1 - 0.0019 18.5 0.1 0.0034 17.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGO19610.1 - 0.0029 17.6 0.3 0.0048 16.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EGO19610.1 - 0.006 16.6 0.2 0.009 16.1 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EGO19610.1 - 0.011 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 EGO19610.1 - 0.018 15.0 0.4 0.033 14.1 0.4 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO19610.1 - 0.025 13.7 0.1 0.03 13.5 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGO19610.1 - 0.042 12.9 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 EGO19610.1 - 0.05 13.4 0.2 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.15 EGO19610.1 - 0.063 13.5 0.1 0.08 13.1 0.1 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 EGO19610.1 - 0.099 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank PF00023.30 EGO19611.1 - 6.8e-10 38.9 0.2 2.7e-07 30.7 0.1 3.1 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EGO19611.1 - 8.2e-10 39.1 0.0 1.4e-07 32.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO19611.1 - 2.7e-07 30.3 0.1 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGO19611.1 - 1.2e-05 25.7 0.1 8.9e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO19611.1 - 0.00056 20.2 0.1 0.007 16.7 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO19612.1 - 1.3e-22 80.1 0.0 2.3e-13 50.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO19612.1 - 2.8e-22 78.8 0.0 2.1e-07 31.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGO19612.1 - 1.8e-17 62.9 0.0 1.7e-05 25.1 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGO19612.1 - 1.3e-16 60.5 0.0 3.4e-06 27.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO19612.1 - 2.2e-15 55.2 0.0 0.00092 19.5 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat SCHIP-1 PF10148.9 EGO19612.1 - 0.0014 18.3 0.9 1.3 8.5 0.0 3.5 4 0 0 4 4 4 2 Schwannomin-interacting protein 1 PEGA PF08308.11 EGO19612.1 - 0.075 12.9 0.0 6.6 6.7 0.0 2.7 3 0 0 3 3 3 0 PEGA domain Endonuc-FokI_C PF09254.11 EGO19612.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 1 1 2 2 2 0 Restriction endonuclease FokI, C terminal AAA_16 PF13191.6 EGO19613.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EGO19613.1 - 0.0024 17.2 0.0 0.0058 15.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 EGO19613.1 - 0.016 15.2 0.1 0.14 12.2 0.0 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGO19613.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGO19613.1 - 0.019 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_32 PF13654.6 EGO19613.1 - 0.02 13.7 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO19613.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EGO19613.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA PF00004.29 EGO19613.1 - 0.071 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGO19613.1 - 0.1 13.0 0.1 0.25 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain DHC_N1 PF08385.12 EGO19614.1 - 2.5e-121 406.1 4.9 7.4e-120 401.2 1.8 2.3 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DUF1241 PF06840.11 EGO19614.1 - 0.12 12.0 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Sec_GG PF07549.14 EGO19616.1 - 0.063 12.8 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 SecD/SecF GG Motif LHC PF00556.20 EGO19616.1 - 1.2 9.4 5.4 0.38 11.0 2.8 1.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit G-alpha PF00503.20 EGO19618.1 - 2.4e-102 342.7 0.0 3.2e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO19618.1 - 1.9e-12 47.0 1.2 9e-08 31.8 0.6 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO19618.1 - 0.0075 16.3 0.4 0.94 9.6 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EGO19618.1 - 0.01 16.0 0.6 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGO19618.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EGO19618.1 - 0.25 10.7 7.1 1.1 8.5 1.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region ANAPC4_WD40 PF12894.7 EGO19619.1 - 4.6e-08 33.3 0.0 0.0032 17.7 0.0 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO19619.1 - 4.5e-07 30.5 0.5 3.1 8.8 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF2415 PF10313.9 EGO19619.1 - 0.016 15.1 0.0 0.059 13.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPO22 PF08631.10 EGO19621.1 - 2.7e-13 50.1 1.3 7.6e-11 42.0 0.1 2.0 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 EGO19621.1 - 0.033 14.4 3.3 0.073 13.3 1.6 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGO19621.1 - 0.086 13.0 1.9 7 7.0 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Gp5_OB PF06714.11 EGO19623.1 - 0.029 14.6 0.0 0.034 14.4 0.0 1.1 1 0 0 1 1 1 0 Gp5 N-terminal OB domain Cyclin PF08613.11 EGO19624.1 - 3.8e-15 56.6 0.0 6.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGO19624.1 - 4.4e-09 36.2 0.0 7.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RicinB_lectin_2 PF14200.6 EGO19628.1 - 2.3e-05 25.1 3.9 0.071 13.8 0.5 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Cullin PF00888.22 EGO19629.1 - 2.3e-144 482.4 3.4 2.9e-144 482.1 3.4 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGO19629.1 - 2.1e-21 75.7 0.0 5.5e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF515 PF04415.12 EGO19629.1 - 0.043 12.2 0.0 0.085 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HTH_IclR PF09339.10 EGO19629.1 - 0.14 12.0 0.2 0.59 10.0 0.3 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Lipase_GDSL_2 PF13472.6 EGO19630.1 - 1.4e-12 48.4 0.0 1.7e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO19630.1 - 4.8e-08 33.2 0.0 2e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase APH PF01636.23 EGO19631.1 - 1.2e-07 31.9 0.3 7.7e-07 29.3 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGO19631.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase 4HBT PF03061.22 EGO19633.1 - 2.2e-10 40.7 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGO19633.1 - 4.4e-05 23.8 0.2 0.00034 21.0 0.0 1.9 2 0 0 2 2 2 1 Thioesterase-like superfamily CCDC66 PF15236.6 EGO19636.1 - 0.00053 19.9 1.6 0.00082 19.2 1.1 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 AF-4 PF05110.13 EGO19636.1 - 0.0057 14.8 2.1 0.0066 14.6 2.1 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PBP PF01161.20 EGO19638.1 - 9.3e-20 71.3 0.2 1.2e-19 70.9 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SR-25 PF10500.9 EGO19639.1 - 0.00046 19.9 13.6 0.00046 19.9 13.6 5.8 6 0 0 6 6 6 2 Nuclear RNA-splicing-associated protein Peptidase_C14 PF00656.22 EGO19641.1 - 1.8e-59 201.7 0.0 2.6e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Pkinase_Tyr PF07714.17 EGO19642.1 - 7.8e-28 97.5 0.0 1.3e-27 96.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO19642.1 - 1.4e-22 80.3 0.0 2.4e-22 79.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGO19642.1 - 0.00039 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Methyltransf_25 PF13649.6 EGO19644.1 - 1.5e-07 32.0 0.1 5.8e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO19644.1 - 0.0019 18.8 0.0 0.0064 17.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO19644.1 - 0.01 16.5 0.0 0.015 16.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain G6PD_bact PF10786.9 EGO19644.1 - 0.2 11.2 0.0 0.43 10.1 0.0 1.5 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) GATase_4 PF13230.6 EGO19647.1 - 1.6e-22 79.7 0.0 2.9e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGO19647.1 - 1e-08 35.5 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain ClpS PF02617.17 EGO19648.1 - 1.5e-08 34.3 0.3 3.4e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 EGO19648.1 - 0.008 16.3 1.1 0.008 16.3 1.1 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) DUF4754 PF15946.5 EGO19648.1 - 0.065 13.5 0.1 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) ELL PF10390.9 EGO19648.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL tRNA-synt_1c PF00749.21 EGO19649.1 - 3.2e-80 269.4 0.0 4.2e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DNA_repr_REX1B PF14966.6 EGO19649.1 - 0.0099 16.5 1.4 0.15 12.8 0.1 2.7 2 1 1 3 3 3 1 DNA repair REX1-B DUF3663 PF12404.8 EGO19649.1 - 0.044 13.8 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase Pkinase PF00069.25 EGO19650.1 - 3.4e-11 43.0 0.0 2.5e-08 33.6 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19650.1 - 0.0094 15.3 0.3 0.019 14.2 0.3 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO19650.1 - 0.22 10.3 0.0 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGO19651.1 - 2.3e-10 40.3 0.0 2.3e-08 33.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19651.1 - 0.0003 20.1 0.3 0.0008 18.8 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Aspzincin_M35 PF14521.6 EGO19651.1 - 0.014 15.9 0.1 7.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase zf_UBZ PF18439.1 EGO19651.1 - 0.034 13.8 2.2 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TRAPP PF04051.16 EGO19652.1 - 1.4e-35 122.2 0.0 1.6e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cytochrom_B561 PF03188.16 EGO19653.1 - 0.35 11.0 5.8 0.13 12.3 1.3 2.5 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 p450 PF00067.22 EGO19655.1 - 9e-29 100.5 0.0 1.6e-27 96.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 LysM PF01476.20 EGO19657.1 - 9.8e-19 67.1 0.1 3.9e-09 36.4 0.1 2.3 2 0 0 2 2 2 2 LysM domain 2-oxoacid_dh PF00198.23 EGO19658.1 - 4.2e-52 176.9 0.0 1.7e-51 175.0 0.0 1.8 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGO19658.1 - 3.1e-19 68.6 0.3 5.8e-19 67.7 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGO19658.1 - 2.8e-13 50.0 0.1 6.3e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGO19658.1 - 3.4e-06 26.8 0.4 8.3e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EGO19658.1 - 0.0067 17.1 0.0 0.025 15.3 0.0 1.9 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 EGO19658.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Pkinase PF00069.25 EGO19659.1 - 0.00033 20.1 0.0 0.047 13.0 0.0 2.6 2 1 0 3 3 3 2 Protein kinase domain Glucosamine_iso PF01182.20 EGO19661.1 - 3.6e-18 66.3 0.0 6.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SIR2 PF02146.17 EGO19662.1 - 1.2e-33 116.5 0.0 2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family LysM PF01476.20 EGO19664.1 - 4e-15 55.6 0.6 2.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 LysM domain F-box-like PF12937.7 EGO19665.1 - 5.9e-08 32.5 0.8 1.8e-07 30.9 0.8 2.0 1 0 0 1 1 1 1 F-box-like ERCC4 PF02732.15 EGO19667.1 - 6.9e-20 71.8 0.0 1.4e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 EGO19667.1 - 0.079 13.6 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Sds3 PF08598.11 EGO19667.1 - 2.8 7.9 5.8 0.68 9.9 0.4 2.4 3 0 0 3 3 3 0 Sds3-like Hormone_3 PF00159.18 EGO19668.1 - 0.0013 18.7 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide Alpha-amylase PF00128.24 EGO19670.1 - 2.7e-113 379.0 1.6 3.7e-113 378.5 1.6 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EGO19670.1 - 9e-08 32.1 0.0 2.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DSPc PF00782.20 EGO19671.1 - 5.1e-07 29.6 0.0 6.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGO19671.1 - 9.7e-06 25.8 0.0 2.2e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGO19671.1 - 9.7e-06 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 EGO19671.1 - 4.8e-05 23.1 0.0 6.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EGO19671.1 - 0.00041 20.0 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGO19671.1 - 0.055 13.1 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family F-box PF00646.33 EGO19672.1 - 4.4e-05 23.2 0.5 9.7e-05 22.1 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO19672.1 - 0.0047 16.8 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 F-box-like DUF4910 PF16254.5 EGO19672.1 - 0.058 12.3 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) DUF3752 PF12572.8 EGO19674.1 - 1.1e-40 139.6 13.4 1.1e-40 139.6 13.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Nucleo_P87 PF07267.11 EGO19674.1 - 8.7 5.1 9.4 15 4.3 9.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VKOR PF07884.14 EGO19675.1 - 0.036 14.3 5.0 0.054 13.7 5.0 1.3 1 1 0 1 1 1 0 Vitamin K epoxide reductase family LysM PF01476.20 EGO19677.1 - 4.9e-13 48.9 0.0 8.9e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 LysM domain Myb_DNA-bind_4 PF13837.6 EGO19678.1 - 0.092 13.1 0.1 0.52 10.7 0.0 2.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO19678.1 - 0.41 10.9 1.7 4.6 7.5 1.7 2.4 1 1 0 1 1 1 0 Myb-like DNA-binding domain Acetyltransf_1 PF00583.25 EGO19680.1 - 0.0012 19.1 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family p450 PF00067.22 EGO19683.1 - 4.9e-70 236.6 0.0 6.1e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 EGO19684.1 - 1.4e-45 155.6 15.2 1.6e-45 155.4 15.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family NmrA PF05368.13 EGO19686.1 - 1.6e-43 149.0 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO19686.1 - 9.4e-21 74.5 0.0 1.3e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO19686.1 - 4.7e-06 26.2 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO19686.1 - 0.00013 21.1 0.1 0.00025 20.1 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGO19686.1 - 0.039 14.4 0.2 0.061 13.8 0.2 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGO19686.1 - 0.15 12.4 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 EGO19687.1 - 4.4e-61 206.5 0.0 5.5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19687.1 - 3.9e-27 95.2 0.0 4.6e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO19687.1 - 5.6e-06 25.9 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGO19687.1 - 0.013 14.4 0.0 0.044 12.7 0.0 1.8 2 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EGO19687.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGO19687.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pectate_lyase_3 PF12708.7 EGO19688.1 - 9.5e-96 319.8 25.7 1e-83 280.4 8.2 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO19688.1 - 4.9e-09 35.8 0.7 0.0018 18.0 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase p450 PF00067.22 EGO19689.1 - 4.9e-66 223.4 0.0 5.8e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGO19691.1 - 1.5e-08 34.4 0.0 8.2e-07 28.6 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19691.1 - 0.0043 16.4 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase LMBR1 PF04791.16 EGO19692.1 - 0.13 11.1 1.4 0.16 10.9 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Epimerase PF01370.21 EGO19693.1 - 1.1e-16 61.1 0.0 3.5e-16 59.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO19693.1 - 3.4e-14 52.5 0.0 5.5e-14 51.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGO19693.1 - 4.8e-11 42.9 0.0 7.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO19693.1 - 6.3e-09 35.4 0.0 7.6e-08 31.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO19693.1 - 2.6e-08 33.7 0.0 4.3e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGO19693.1 - 3.3e-06 26.8 0.2 2.9e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EGO19693.1 - 0.00012 21.6 0.9 0.00056 19.4 0.5 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EGO19693.1 - 0.00026 20.2 0.1 0.00036 19.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 EGO19693.1 - 0.0067 16.0 0.3 0.037 13.6 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO19693.1 - 0.012 15.6 0.1 0.18 11.7 0.1 2.2 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 EGO19693.1 - 0.057 12.5 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.21 EGO19694.1 - 1.9e-19 70.1 0.1 3.6e-19 69.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO19694.1 - 5.5e-13 48.6 0.1 8.2e-13 48.0 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGO19694.1 - 1.7e-11 44.1 0.1 4e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO19694.1 - 3.9e-11 43.2 0.6 6.2e-11 42.5 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO19694.1 - 9.1e-11 41.4 0.1 1.9e-09 37.1 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGO19694.1 - 1.5e-06 27.6 0.1 2e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGO19694.1 - 2.6e-05 23.8 0.1 0.00068 19.2 0.2 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EGO19694.1 - 6e-05 22.7 0.4 0.00058 19.5 0.1 2.1 1 1 1 2 2 2 1 NmrA-like family KR PF08659.10 EGO19694.1 - 0.0022 17.9 0.0 0.0051 16.7 0.0 1.6 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.16 EGO19695.1 - 7.9e-39 133.6 19.6 7.9e-39 133.6 19.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO19695.1 - 5.7e-17 61.7 2.4 5.7e-17 61.7 2.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.11 EGO19695.1 - 0.0014 18.7 7.8 0.0039 17.3 0.4 3.2 3 0 0 3 3 3 2 Membrane bound YbgT-like protein p450 PF00067.22 EGO19696.1 - 5.3e-71 239.7 0.0 6.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 EGO19696.1 - 0.1 12.8 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Serine endopeptidase inhibitors p450 PF00067.22 EGO19697.1 - 4.4e-69 233.4 0.0 5.2e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EGO19698.1 - 1.8e-11 44.6 0.2 1.1e-07 32.3 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pectate_lyase_3 PF12708.7 EGO19699.1 - 3.4e-83 278.7 12.9 2.3e-71 240.0 6.1 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO19699.1 - 3.1e-08 33.2 0.5 0.0021 17.7 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Retrotrans_gag PF03732.17 EGO19703.1 - 2.6e-06 27.6 3.3 3e-06 27.4 1.6 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO19703.1 - 6.5e-06 26.0 1.8 1.2e-05 25.1 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF842 PF05811.13 EGO19703.1 - 0.049 13.3 1.9 0.099 12.3 1.9 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Chromo PF00385.24 EGO19704.1 - 6.7e-08 32.3 0.0 2.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YL1 PF05764.13 EGO19704.1 - 0.00053 20.2 16.3 0.00087 19.5 16.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SR-25 PF10500.9 EGO19704.1 - 0.0026 17.4 14.8 0.0043 16.7 14.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGO19704.1 - 0.035 13.4 15.0 0.055 12.8 15.0 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGO19704.1 - 0.21 9.9 14.9 0.3 9.3 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.9 EGO19704.1 - 0.23 11.5 6.3 0.43 10.6 6.3 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Membralin PF09746.9 EGO19704.1 - 0.54 9.2 2.7 0.83 8.6 2.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein eIF-3c_N PF05470.12 EGO19704.1 - 1.9 6.7 12.0 2.8 6.1 12.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cwf_Cwc_15 PF04889.12 EGO19704.1 - 2.1 8.0 19.7 4 7.1 19.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 EGO19704.1 - 3.4 6.6 9.4 6 5.8 9.4 1.4 1 0 0 1 1 1 0 Pes-10 Epimerase PF01370.21 EGO19708.1 - 5.1e-18 65.4 0.1 1e-17 64.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO19708.1 - 2.7e-11 43.0 0.0 3.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGO19708.1 - 3.7e-11 43.2 0.0 5.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGO19708.1 - 1.4e-09 37.8 0.1 1e-08 35.0 0.0 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGO19708.1 - 1.2e-08 34.4 0.1 1.2e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EGO19708.1 - 5.1e-06 26.2 0.1 2.1e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EGO19708.1 - 0.0011 18.4 0.3 0.0025 17.3 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EGO19708.1 - 0.011 14.9 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EGO19708.1 - 0.016 15.1 0.1 0.25 11.2 0.1 2.2 1 1 0 1 1 1 0 KR domain Phosducin PF02114.16 EGO19710.1 - 1.4e-18 66.8 0.0 1.1e-08 34.4 0.0 3.1 2 1 1 3 3 3 3 Phosducin MFS_1 PF07690.16 EGO19711.1 - 2.9e-11 42.9 62.2 3.1e-08 32.9 37.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily SAE2 PF08573.10 EGO19712.1 - 8.4e-23 81.6 0.5 1.6e-22 80.7 0.5 1.4 1 0 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TMF_TATA_bd PF12325.8 EGO19713.1 - 0.0038 17.4 0.2 0.0071 16.5 0.2 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DMAP1 PF05499.12 EGO19713.1 - 0.0069 16.3 3.7 0.72 9.7 0.2 2.1 1 1 1 2 2 2 2 DNA methyltransferase 1-associated protein 1 (DMAP1) Atg14 PF10186.9 EGO19713.1 - 0.053 12.6 0.5 0.055 12.6 0.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 EGO19713.1 - 0.06 13.8 0.2 0.094 13.2 0.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB SHE3 PF17078.5 EGO19713.1 - 0.063 13.0 2.7 0.057 13.1 1.6 1.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Cep57_MT_bd PF06657.13 EGO19713.1 - 0.07 13.6 0.2 0.07 13.6 0.2 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uso1_p115_C PF04871.13 EGO19713.1 - 0.072 13.5 8.3 1.1 9.6 0.8 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-Q PF13094.6 EGO19713.1 - 0.077 13.2 4.7 0.098 12.9 4.7 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.11 EGO19713.1 - 0.13 12.5 2.0 0.29 11.4 2.0 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4449 PF14613.6 EGO19714.1 - 5.3e-33 114.4 4.6 5.3e-33 114.4 4.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) UPF0047 PF01894.17 EGO19715.1 - 9.5e-37 125.7 0.0 1.1e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CCCH PF00642.24 EGO19716.1 - 2.9e-20 71.7 21.2 2.6e-05 24.0 0.6 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO19716.1 - 4.1e-14 52.1 27.3 1.1e-06 28.5 2.1 4.9 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EGO19716.1 - 3.1e-08 34.3 19.5 0.0004 21.1 0.3 4.6 1 1 4 5 5 5 3 Torus domain zf-CCCH_2 PF14608.6 EGO19716.1 - 1.6e-05 25.2 24.8 0.0029 18.0 0.5 5.3 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGO19716.1 - 2.6e-05 23.9 0.4 2.6e-05 23.9 0.4 5.2 6 0 0 6 6 6 1 CCCH-type zinc finger zf-CCHC PF00098.23 EGO19716.1 - 0.00038 20.4 3.7 0.00038 20.4 3.7 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO19716.1 - 0.0013 18.6 0.1 0.0035 17.3 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO19716.1 - 0.041 13.7 3.1 0.26 11.2 3.1 2.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_3 PF15663.5 EGO19716.1 - 0.46 10.7 14.9 2.9 8.1 0.4 3.8 1 1 3 4 4 4 0 Zinc-finger containing family DUF5613 PF18467.1 EGO19719.1 - 0.0057 17.0 1.5 1.7 9.1 0.3 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF5613) Toprim_N PF08275.11 EGO19719.1 - 0.061 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain NmrA PF05368.13 EGO19722.1 - 4.1e-30 105.1 0.0 4.8e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO19722.1 - 5.7e-13 49.2 0.0 6.5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO19722.1 - 3.2e-06 26.4 0.0 3.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO19722.1 - 0.098 12.1 0.0 1.6 8.2 0.0 1.9 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Mur_ligase PF01225.25 EGO19722.1 - 0.1 13.0 0.0 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Mur ligase family, catalytic domain NmrA PF05368.13 EGO19723.1 - 7.3e-49 166.4 0.2 8.7e-49 166.2 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO19723.1 - 4.1e-22 79.0 0.1 5.5e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO19723.1 - 5.6e-10 38.7 0.1 2.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO19723.1 - 3.9e-06 26.5 0.0 5.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO19723.1 - 0.0028 18.1 0.1 0.0055 17.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 EGO19723.1 - 0.044 13.2 0.2 0.072 12.5 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 EGO19723.1 - 0.065 13.5 0.0 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain KR PF08659.10 EGO19723.1 - 0.077 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 KR domain Cir_N PF10197.9 EGO19724.1 - 9.2e-07 29.0 0.0 9.2e-07 29.0 0.0 3.1 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4658 PF15555.6 EGO19724.1 - 0.61 10.2 3.4 0.21 11.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Pectate_lyase_3 PF12708.7 EGO19725.1 - 4.2e-93 311.1 19.3 1.6e-81 273.2 6.0 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO19725.1 - 1.9e-07 30.6 5.7 0.0051 16.5 0.3 3.2 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase p450 PF00067.22 EGO19726.1 - 1.7e-66 224.9 0.0 2e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4874 PF16173.5 EGO19726.1 - 0.097 12.3 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) p450 PF00067.22 EGO19727.1 - 2.7e-67 227.5 0.0 3.9e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TT_ORF2 PF02957.15 EGO19729.1 - 0.094 13.6 0.8 0.28 12.1 0.8 1.8 1 0 0 1 1 1 0 TT viral ORF2 MAP65_ASE1 PF03999.12 EGO19729.1 - 0.5 9.0 2.4 0.73 8.5 2.4 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) YL1 PF05764.13 EGO19729.1 - 6.7 6.7 10.9 1.6 8.8 7.6 1.6 2 0 0 2 2 2 0 YL1 nuclear protein DEAD PF00270.29 EGO19730.1 - 5.3e-45 153.3 0.0 8.4e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO19730.1 - 6.8e-25 87.6 0.1 8.3e-24 84.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGO19730.1 - 2.8e-18 65.9 2.4 3e-18 65.8 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGO19730.1 - 0.0057 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 EGO19731.1 - 7.9e-55 186.1 0.0 1.7e-25 89.9 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EGO19731.1 - 1.8e-45 155.5 0.0 1.8e-45 155.5 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EGO19731.1 - 3.4e-26 92.1 0.0 3.1e-11 43.1 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EGO19731.1 - 1.2e-08 35.2 0.4 3.9e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 RWD domain APH PF01636.23 EGO19731.1 - 0.0003 20.8 0.6 0.011 15.6 0.0 2.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGO19731.1 - 0.01 15.5 0.0 6 6.4 0.0 2.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGO19731.1 - 0.018 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF2102 PF09875.9 EGO19731.1 - 0.15 11.7 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) ATP-synt_B PF00430.18 EGO19731.1 - 0.36 10.9 12.8 0.89 9.6 12.8 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DRY_EERY PF09750.9 EGO19731.1 - 0.96 9.7 6.7 2.3 8.5 6.7 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Pkinase PF00069.25 EGO19733.1 - 7.1e-07 28.8 0.0 8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO19733.1 - 2e-06 27.9 0.1 2.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO19733.1 - 0.00029 20.2 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO19733.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.3 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.11 EGO19733.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 EGO19733.1 - 0.019 13.8 0.0 0.024 13.4 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EGO19733.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EGO19733.1 - 0.046 13.0 0.0 0.086 12.1 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.17 EGO19733.1 - 0.059 12.6 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Hydrophobin PF01185.18 EGO19734.1 - 1.1e-26 93.3 11.0 1.3e-26 93.0 11.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF1427 PF07235.11 EGO19734.1 - 0.01 15.8 1.4 0.33 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Gly-zipper_YMGG PF13441.6 EGO19734.1 - 0.19 11.5 2.1 0.38 10.5 2.1 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper CoatB PF10389.9 EGO19734.1 - 0.27 11.1 1.5 0.48 10.3 1.5 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B ORC5_C PF14630.6 EGO19735.1 - 1.8e-59 201.6 0.0 2.3e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus YycC PF14174.6 EGO19735.1 - 0.018 14.8 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 YycC-like protein Ribosomal_L7Ae PF01248.26 EGO19736.1 - 2.5e-22 78.4 1.1 4.3e-22 77.7 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNA_pol_Rpb1_1 PF04997.12 EGO19737.1 - 2.8e-108 362.0 0.0 4e-108 361.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGO19737.1 - 2.4e-102 341.9 0.0 3.4e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGO19737.1 - 5e-74 248.0 0.0 9.9e-74 247.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGO19737.1 - 2.7e-67 226.3 0.0 4.7e-67 225.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGO19737.1 - 1.2e-49 168.3 0.0 3.4e-49 166.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGO19737.1 - 4.3e-48 162.7 0.0 7.9e-48 161.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGO19737.1 - 3.4e-36 123.5 0.0 6.4e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGO19737.1 - 7.6e-08 32.3 187.9 0.023 15.0 10.3 13.5 6 1 2 12 12 12 7 RNA polymerase Rpb1 C-terminal repeat Retrotrans_gag PF03732.17 EGO19738.1 - 1.9e-07 31.2 0.1 1.9e-07 31.2 0.1 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO19738.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) rve PF00665.26 EGO19739.1 - 3.6e-05 23.9 0.0 0.00081 19.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO19739.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain YL1 PF05764.13 EGO19741.1 - 0.0091 16.1 14.9 0.0091 16.1 14.9 1.5 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 EGO19741.1 - 0.0094 14.3 5.3 0.0091 14.3 5.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Mit_KHE1 PF10173.9 EGO19741.1 - 0.17 12.0 1.4 0.32 11.1 1.4 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related BUD22 PF09073.10 EGO19741.1 - 0.19 11.0 17.5 0.023 14.1 13.7 1.3 2 0 0 2 2 2 0 BUD22 Pes-10 PF07149.11 EGO19741.1 - 1.3 8.0 8.6 2.2 7.2 8.6 1.4 1 0 0 1 1 1 0 Pes-10 SR-25 PF10500.9 EGO19741.1 - 2.8 7.5 19.2 0.038 13.6 12.1 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_phi PF04931.13 EGO19741.1 - 6.2 4.8 17.1 9.9 4.1 17.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-bind_3 PF12776.7 EGO19743.1 - 2.5e-05 25.1 0.1 0.047 14.7 0.0 2.9 1 1 2 3 3 3 2 Myb/SANT-like DNA-binding domain DEAD PF00270.29 EGO19746.1 - 0.00057 19.7 0.1 0.00062 19.6 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pkinase PF00069.25 EGO19747.1 - 2.1e-53 181.4 0.0 3.3e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19747.1 - 2.4e-34 118.8 0.0 5.5e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Plk4_PB2 PF18409.1 EGO19747.1 - 4.4e-07 30.6 0.2 7.4e-06 26.6 0.1 2.7 2 1 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 Kinase-like PF14531.6 EGO19747.1 - 5.7e-07 29.1 0.0 9.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Plk4_PB1 PF18190.1 EGO19747.1 - 9.3e-07 29.0 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 APH PF01636.23 EGO19747.1 - 0.033 14.1 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO19748.1 - 2.6e-08 33.1 0.0 4.3e-08 32.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase CLIP_SPH_Scar PF18399.1 EGO19749.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Clip-domain serine protease homolog Scarface Hid1 PF12722.7 EGO19751.1 - 1.4e-185 618.9 0.0 1.6e-185 618.6 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGO19751.1 - 1.1e-95 321.4 0.0 1.4e-95 321.1 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein pKID PF02173.17 EGO19752.1 - 0.063 12.7 6.5 5.9 6.4 0.0 4.1 4 0 0 4 4 4 0 pKID domain Methyltransf_2 PF00891.18 EGO19753.1 - 4.6e-16 58.7 0.0 2.7e-12 46.5 0.0 2.5 1 1 0 2 2 2 2 O-methyltransferase domain PCMT PF01135.19 EGO19753.1 - 0.0078 16.0 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rrf2 PF02082.20 EGO19753.1 - 0.011 16.0 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator Methyltransf_23 PF13489.6 EGO19753.1 - 0.048 13.5 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EGO19753.1 - 0.2 11.4 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Sec_GG PF07549.14 EGO19755.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif UCH PF00443.29 EGO19756.1 - 7.6e-38 130.5 0.0 1.7e-37 129.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGO19756.1 - 9.6e-24 83.5 11.6 2e-19 69.7 1.5 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EGO19756.1 - 8.6e-23 79.9 0.1 1.4e-10 40.9 0.0 2.9 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP_var PF17807.1 EGO19756.1 - 2.2e-22 78.6 3.7 7.3e-22 76.9 0.7 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 EGO19756.1 - 2.9e-13 50.1 0.0 6.9e-10 39.0 0.0 3.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase HSP70 PF00012.20 EGO19757.1 - 1.7e-58 198.3 3.7 1.3e-44 152.4 0.0 2.6 2 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EGO19757.1 - 6.3e-11 41.7 0.0 4.6e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein dCMP_cyt_deam_1 PF00383.23 EGO19758.1 - 9e-17 60.8 0.0 1.8e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO19758.1 - 5.9e-16 58.5 0.0 8.2e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGO19758.1 - 0.0016 18.6 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EGO19758.1 - 0.003 17.6 0.0 0.022 14.8 0.0 1.9 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EGO19758.1 - 0.0055 16.8 0.0 0.038 14.1 0.0 1.9 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 EGO19758.1 - 0.039 14.1 0.0 0.09 12.9 0.0 1.5 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 EGO19758.1 - 0.062 13.2 0.0 0.084 12.8 0.0 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC3 PF18771.1 EGO19758.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.5 2 0 0 2 2 2 0 APOBEC3 Bd3614-deam PF14439.6 EGO19758.1 - 0.25 11.4 0.9 0.51 10.4 0.8 1.6 1 1 1 2 2 2 0 Bd3614-like deaminase PhaP_Bmeg PF09602.10 EGO19759.1 - 0.058 13.3 0.0 0.092 12.7 0.0 1.4 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HALZ PF02183.18 EGO19759.1 - 0.062 13.5 1.7 0.062 13.5 1.7 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Oxysterol_BP PF01237.18 EGO19761.1 - 4.2e-132 440.5 0.0 7.1e-132 439.7 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 EGO19761.1 - 1.2e-13 51.0 0.2 1.2e-05 25.4 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO19761.1 - 8.8e-12 44.1 0.4 0.0022 18.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGO19761.1 - 1.2e-10 41.8 0.0 2.1e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO19761.1 - 2.5e-10 40.3 1.3 0.0024 18.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 EGO19761.1 - 4.4e-09 36.8 0.0 1.1e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGO19761.1 - 1e-06 28.9 0.4 4.6e-06 26.8 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain Ank_4 PF13637.6 EGO19761.1 - 1.3e-06 28.9 0.2 0.0053 17.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_11 PF15413.6 EGO19761.1 - 0.00042 20.7 0.1 0.0012 19.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain AA_permease PF00324.21 EGO19762.1 - 3.9e-121 405.0 35.5 4.4e-121 404.8 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO19762.1 - 6e-31 107.7 39.5 7.4e-31 107.4 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Mem_trans PF03547.18 EGO19763.1 - 1.3e-12 46.9 0.0 2e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Gpr1_Fun34_YaaH PF01184.19 EGO19764.1 - 2.6e-74 249.3 17.1 3.3e-74 249.0 17.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1582 PF07621.11 EGO19764.1 - 0.035 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) NAP PF00956.18 EGO19765.1 - 3e-15 56.1 1.6 4.8e-15 55.5 1.6 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) TauD PF02668.16 EGO19766.1 - 2.6e-61 207.8 1.4 3.2e-61 207.5 1.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-4CXXC_R1 PF10497.9 EGO19767.1 - 3e-05 24.2 5.8 3.9e-05 23.8 5.8 1.1 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_4 PF15227.6 EGO19767.1 - 0.23 11.6 3.7 0.49 10.6 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGO19767.1 - 0.31 10.9 9.8 0.3 11.0 0.5 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGO19767.1 - 2.5 8.3 11.9 7 6.9 11.9 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.6 EGO19767.1 - 2.9 8.3 11.0 2.9 8.3 2.4 2.2 1 1 1 2 2 2 0 Ring finger domain HAD_2 PF13419.6 EGO19769.1 - 1.6e-08 34.9 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO19769.1 - 3.3e-05 24.3 0.0 5.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO19769.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4942 PF13708.6 EGO19769.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Glyco_hydro_61 PF03443.14 EGO19770.1 - 2.2e-50 171.5 0.1 2.8e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PRR18 PF15671.5 EGO19770.1 - 0.011 15.6 8.4 0.024 14.5 8.4 1.4 1 0 0 1 1 1 0 Proline-rich protein family 18 Glyco_hydro_61 PF03443.14 EGO19771.1 - 4.8e-55 186.7 0.2 5.9e-55 186.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_31 PF01055.26 EGO19773.1 - 3.6e-140 468.1 6.0 4.3e-140 467.8 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGO19773.1 - 1.2e-27 96.3 0.0 2.5e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGO19773.1 - 0.00099 19.4 0.2 0.0066 16.7 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Retrotran_gag_2 PF14223.6 EGO19774.1 - 1.5e-16 60.3 0.4 2e-16 59.9 0.4 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_hydro_31 PF01055.26 EGO19776.1 - 7.1e-142 473.7 2.7 8.8e-142 473.4 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGO19776.1 - 3.9e-28 98.0 0.0 7.6e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGO19776.1 - 4.2e-05 23.8 0.1 0.00021 21.6 0.1 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like PNP_UDP_1 PF01048.20 EGO19777.1 - 6.4e-21 74.7 0.0 8.7e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HMG_box PF00505.19 EGO19778.1 - 8e-16 58.2 2.8 9.6e-16 58.0 1.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO19778.1 - 5.5e-13 49.3 0.4 1e-12 48.5 0.4 1.4 1 0 0 1 1 1 1 HMG-box domain Fasciclin PF02469.22 EGO19780.1 - 1.7e-31 109.1 1.9 2.7e-20 72.9 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.25 EGO19781.1 - 1.5e-68 231.0 0.0 1.7e-66 224.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19781.1 - 1.3e-35 122.9 0.0 6.1e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO19781.1 - 1.9e-06 27.0 0.0 2.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO19781.1 - 8e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGO19781.1 - 0.004 16.7 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EGO19781.1 - 0.0073 15.7 0.7 0.014 14.8 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3602 PF12223.8 EGO19781.1 - 0.028 15.0 1.6 0.067 13.8 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) APH PF01636.23 EGO19781.1 - 0.037 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Putative_PNPOx PF01243.20 EGO19782.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_90 PF05686.12 EGO19784.1 - 4.7e-37 127.8 0.0 1.2e-18 67.2 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 90 MtmB PF05369.12 EGO19784.1 - 0.0026 16.6 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Monomethylamine methyltransferase MtmB HMG_box PF00505.19 EGO19784.1 - 0.37 11.2 1.9 7.1 7.1 0.2 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box DUF5420 PF17457.2 EGO19785.1 - 0.079 12.8 0.0 0.082 12.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5420) Asp_protease_2 PF13650.6 EGO19786.1 - 6.7e-05 23.4 0.0 0.00012 22.7 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO19786.1 - 0.00056 20.4 0.0 0.00093 19.7 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO19786.1 - 0.009 15.8 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EGO19787.1 - 1.8e-08 34.5 0.5 7.2e-08 32.6 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO19787.1 - 1.3e-06 28.1 1.8 2.8e-06 27.2 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO19787.1 - 0.039 13.8 0.4 0.075 12.9 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO19787.1 - 0.73 9.9 7.4 0.26 11.3 4.6 1.7 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 EGO19790.1 - 9.5e-08 31.7 0.0 2.2e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19790.1 - 0.013 14.8 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Glyco_transf_90 PF05686.12 EGO19794.1 - 1.9e-12 46.8 0.2 3.4e-11 42.7 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 90 MtmB PF05369.12 EGO19794.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB VHP PF02209.19 EGO19795.1 - 0.3 11.2 7.1 15 5.7 0.4 3.7 1 1 3 4 4 4 0 Villin headpiece domain EBP PF05241.12 EGO19798.1 - 0.0066 15.9 10.1 0.015 14.8 10.1 1.6 1 1 0 1 1 1 1 Emopamil binding protein Bestrophin PF01062.21 EGO19799.1 - 1.6e-16 60.6 8.1 4.1e-10 39.5 0.7 3.1 3 0 0 3 3 3 3 Bestrophin, RFP-TM, chloride channel HGTP_anticodon PF03129.20 EGO19800.1 - 1.2e-21 76.7 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGO19800.1 - 1.5e-10 41.3 0.0 4.8e-10 39.7 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) p450 PF00067.22 EGO19803.1 - 3e-52 177.9 0.0 3.7e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF565 PF04483.12 EGO19805.1 - 1.8 9.2 5.4 1.3 9.6 1.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF565) ATG27 PF09451.10 EGO19806.1 - 0.0022 17.9 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 APG12 PF04110.13 EGO19807.1 - 3.8e-30 104.1 0.0 4.7e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGO19807.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like FAD-oxidase_C PF02913.19 EGO19810.1 - 5.6e-50 170.3 0.0 6.8e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO19810.1 - 4.9e-34 117.0 0.3 7.7e-34 116.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.11 EGO19810.1 - 0.0036 16.7 0.0 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding VHS PF00790.19 EGO19811.1 - 2.9e-35 121.2 0.0 1e-34 119.4 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EGO19811.1 - 2.6e-18 66.1 0.3 2.3e-17 63.0 0.1 2.7 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 EGO19811.1 - 0.0098 15.5 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 GGA N-GAT domain HR1 PF02185.16 EGO19811.1 - 0.51 10.5 3.7 0.14 12.3 0.5 1.7 2 0 0 2 2 2 0 Hr1 repeat zf-C2H2 PF00096.26 EGO19812.1 - 6.7e-07 29.4 7.3 0.00083 19.7 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO19812.1 - 0.00066 20.0 2.3 0.00066 20.0 2.3 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO19812.1 - 0.00067 20.3 6.3 0.04 14.8 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger Sina PF03145.16 EGO19812.1 - 0.0013 18.7 1.9 0.0022 18.0 1.3 1.6 1 1 1 2 2 2 1 Seven in absentia protein family zf-H2C2_5 PF13909.6 EGO19812.1 - 0.03 14.1 2.7 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain OrsD PF12013.8 EGO19812.1 - 0.072 13.5 4.7 2 8.9 0.1 3.2 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-TRAF PF02176.18 EGO19812.1 - 5.7 7.7 7.8 4 8.2 1.8 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger 4HBT PF03061.22 EGO19814.1 - 2.3e-08 34.3 0.0 4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGO19814.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily zf-RING_2 PF13639.6 EGO19816.1 - 2.5e-12 46.9 6.5 4e-12 46.3 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO19816.1 - 4.6e-07 29.6 2.7 6.9e-07 29.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO19816.1 - 9.5e-07 28.6 6.2 1.6e-06 27.9 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO19816.1 - 1.1e-06 28.5 1.9 1.7e-06 27.9 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO19816.1 - 2.6e-06 27.2 4.6 4e-06 26.6 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO19816.1 - 6.3e-06 25.8 1.2 1.7e-05 24.4 0.6 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGO19816.1 - 6.8e-06 26.0 6.3 1.5e-05 24.9 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGO19816.1 - 6.1e-05 23.2 11.8 0.00019 21.7 10.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO19816.1 - 0.00036 20.3 8.2 0.00044 20.0 2.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGO19816.1 - 0.0052 16.8 5.1 0.02 14.9 5.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO19816.1 - 0.016 15.0 2.7 0.033 14.0 2.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EGO19816.1 - 0.024 14.3 2.4 0.024 14.3 2.4 2.1 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.7 EGO19816.1 - 0.35 11.0 11.4 0.72 10.0 8.9 2.2 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 EGO19816.1 - 0.45 10.7 5.6 0.75 10.0 5.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 EGO19816.1 - 0.51 10.3 4.3 0.62 10.0 3.1 1.7 1 1 1 2 2 2 0 PHD-finger Rad50_zn_hook PF04423.14 EGO19816.1 - 0.54 10.1 2.0 31 4.5 0.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF4707 PF15806.5 EGO19816.1 - 0.8 8.6 3.3 1.2 8.0 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) FANCL_C PF11793.8 EGO19816.1 - 1.5 9.1 7.5 13 6.0 7.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EGO19816.1 - 1.7 8.3 8.5 1.9 8.1 7.4 1.6 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type UQ_con PF00179.26 EGO19818.1 - 8.9e-48 161.5 0.0 9.9e-48 161.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO19818.1 - 0.0008 19.1 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGO19818.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EGO19818.1 - 0.064 13.5 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Skp1_POZ PF03931.15 EGO19819.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Metallophos PF00149.28 EGO19820.1 - 2.1e-35 123.1 0.0 3.4e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAT PF04768.13 EGO19821.1 - 7e-45 152.7 0.0 1.1e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EGO19821.1 - 2.4e-26 92.5 0.0 2e-25 89.5 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EGO19821.1 - 5.5e-25 88.4 0.0 1e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 EGO19821.1 - 0.0006 19.9 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain IFT46_B_C PF12317.8 EGO19822.1 - 0.056 13.2 0.0 0.059 13.1 0.0 1.0 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF5519 PF17648.1 EGO19824.1 - 0.049 13.5 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Baculo_PEP_C PF04513.12 EGO19825.1 - 0.029 14.4 11.0 0.18 11.9 1.8 2.8 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLASP_N PF12348.8 EGO19825.1 - 0.064 12.8 1.5 0.097 12.2 1.5 1.3 1 0 0 1 1 1 0 CLASP N terminal Hydrolase_4 PF12146.8 EGO19826.1 - 2.9e-14 52.9 0.0 5e-11 42.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO19826.1 - 5.9e-13 49.0 0.1 4.2e-12 46.3 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EGO19826.1 - 7.7e-09 35.8 0.0 1.4e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGO19826.1 - 4.7e-07 30.6 0.0 7.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGO19826.1 - 7.7e-06 25.9 0.0 0.052 13.3 0.0 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 EGO19826.1 - 0.00033 19.4 0.1 0.047 12.4 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 EGO19826.1 - 0.00057 19.5 0.0 0.012 15.2 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EGO19826.1 - 0.0043 16.7 0.0 0.17 11.5 0.0 2.3 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EGO19826.1 - 0.0052 16.7 0.2 0.01 15.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGO19826.1 - 0.0079 15.9 0.1 0.012 15.2 0.1 1.4 1 1 0 1 1 1 1 Putative esterase DUF1057 PF06342.12 EGO19826.1 - 0.0093 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF818 PF05677.12 EGO19826.1 - 0.01 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 EGO19826.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGO19826.1 - 0.013 15.0 0.0 0.14 11.6 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 EGO19826.1 - 0.043 13.4 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 EGO19826.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EGO19826.1 - 0.18 11.6 0.0 2 8.2 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO19826.1 - 0.22 11.2 0.7 1.1 8.9 0.7 2.1 1 1 0 1 1 1 0 PGAP1-like protein HORMA PF02301.18 EGO19827.1 - 3e-15 56.4 0.1 4.4e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EGO19827.1 - 0.0057 16.6 0.2 0.11 12.5 0.2 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 FmrO PF07091.11 EGO19827.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Peptidase_M1 PF01433.20 EGO19829.1 - 1.3e-33 116.4 0.0 2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGO19829.1 - 2.6e-31 108.0 0.0 5e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGO19829.1 - 6.1e-19 68.9 0.0 9.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Myosin_head PF00063.21 EGO19830.1 - 7.3e-42 143.5 0.0 8.5e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) zf-C2H2_4 PF13894.6 EGO19832.1 - 0.0032 18.2 2.8 0.029 15.2 0.1 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO19832.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 zinc-finger C2H2-type Lar_restr_allev PF14354.6 EGO19832.1 - 0.024 15.0 0.5 8.9 6.8 0.0 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar SEEK1 PF15357.6 EGO19832.1 - 0.034 14.3 1.0 0.052 13.7 1.0 1.2 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 zf-C2H2 PF00096.26 EGO19832.1 - 0.038 14.4 0.3 0.038 14.4 0.3 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF1179 PF06678.11 EGO19832.1 - 0.2 11.7 1.1 0.35 10.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) HypA PF01155.19 EGO19832.1 - 0.21 11.6 1.7 1.8 8.6 0.8 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 EGO19832.1 - 0.23 11.8 2.4 23 5.4 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO19832.1 - 0.42 11.1 2.9 0.98 9.9 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGO19833.1 - 5.5e-05 23.4 7.7 0.0008 19.7 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO19833.1 - 0.00053 19.9 0.1 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGO19833.1 - 0.0015 19.2 7.0 0.014 16.2 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 EGO19833.1 - 0.0036 17.3 2.7 0.18 11.9 0.8 2.5 2 0 0 2 2 2 1 BED zinc finger zf-met PF12874.7 EGO19833.1 - 0.018 15.4 0.4 11 6.6 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MAJIN PF15077.6 EGO19833.1 - 1 9.1 14.0 1.9 8.2 2.8 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein RRM_1 PF00076.22 EGO19834.1 - 7.4e-19 67.4 0.0 1.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGO19834.1 - 0.0034 17.3 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 RL domain RRM_5 PF13893.6 EGO19834.1 - 0.0055 16.3 0.0 0.0098 15.5 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Catalase PF00199.19 EGO19835.1 - 3.4e-187 622.2 0.2 4.3e-187 621.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGO19835.1 - 1e-17 64.1 0.1 2.4e-17 62.9 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Rhodanese PF00581.20 EGO19836.1 - 9.3e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 EGO19836.1 - 0.13 12.8 0.2 6.4 7.3 0.1 2.4 2 1 0 2 2 2 0 RlmM ferredoxin-like domain Ctr PF04145.15 EGO19837.1 - 2.4e-21 76.9 0.0 3.3e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.15 EGO19838.1 - 2.7e-21 76.7 0.0 3.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family rRNA_proc-arch PF13234.6 EGO19839.1 - 1.3e-86 290.9 0.0 2.2e-86 290.2 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EGO19839.1 - 1.4e-49 167.9 0.4 2.9e-49 166.9 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EGO19839.1 - 6.9e-18 65.0 0.2 4e-17 62.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO19839.1 - 1e-06 29.1 0.0 4.2e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO19839.1 - 0.0011 19.1 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EGO19839.1 - 0.018 14.1 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGO19839.1 - 0.06 13.6 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain vATP-synt_E PF01991.18 EGO19840.1 - 2.8e-55 186.9 9.6 3.2e-55 186.7 9.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RsmJ PF04378.13 EGO19840.1 - 0.049 12.9 0.3 0.075 12.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ ANF_receptor PF01094.28 EGO19840.1 - 0.049 12.7 0.7 0.074 12.1 0.7 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region DUF883 PF05957.13 EGO19840.1 - 0.73 10.5 7.0 0.25 12.0 2.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WD40 PF00400.32 EGO19841.1 - 3.2e-82 268.3 64.7 1.4e-08 35.3 0.6 15.7 14 1 0 14 14 14 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO19841.1 - 2.1e-38 130.5 0.4 0.00089 19.5 0.0 11.3 1 1 10 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO19841.1 - 3e-14 52.7 1.9 0.56 9.1 0.0 8.7 3 3 5 9 9 9 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO19841.1 - 1.8e-12 46.9 25.8 1.4 8.9 0.0 11.0 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat C2 PF00168.30 EGO19841.1 - 2e-09 37.6 0.0 5.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain eIF2A PF08662.11 EGO19841.1 - 3.1e-09 37.0 0.0 0.045 13.6 0.0 4.5 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO19841.1 - 1.7e-06 27.6 0.2 4.3 6.6 0.0 6.6 7 2 1 8 8 8 2 WD40-like domain Frtz PF11768.8 EGO19841.1 - 5.5e-06 25.0 0.0 0.18 10.1 0.0 4.9 2 1 2 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Gmad1 PF10647.9 EGO19841.1 - 6.6e-05 22.8 1.3 0.048 13.4 0.0 4.5 3 3 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain NACHT PF05729.12 EGO19841.1 - 0.00069 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO19841.1 - 0.00077 19.9 1.5 0.0035 17.8 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain PQQ PF01011.21 EGO19841.1 - 0.0034 17.2 1.4 2.1 8.4 0.0 5.3 5 0 0 5 5 5 1 PQQ enzyme repeat NB-ARC PF00931.22 EGO19841.1 - 0.0056 15.9 0.0 0.0096 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 EGO19841.1 - 0.026 14.9 0.0 0.13 12.7 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Nup160 PF11715.8 EGO19841.1 - 0.029 13.0 1.4 4.3 5.9 0.0 4.1 5 1 0 5 5 5 0 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 EGO19841.1 - 0.087 11.6 0.7 18 4.0 0.0 4.7 3 2 2 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_33 PF13671.6 EGO19841.1 - 0.096 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGO19841.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 EGO19841.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DPPIV_N PF00930.21 EGO19841.1 - 0.15 10.8 0.1 73 2.0 0.0 4.7 5 3 1 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.6 EGO19841.1 - 0.17 11.2 3.2 22 4.2 0.0 5.2 4 2 3 8 8 8 0 Neuroblastoma-amplified sequence, N terminal Glyco_hyd_65N_2 PF14498.6 EGO19842.1 - 3.5e-49 167.8 0.3 5.3e-49 167.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Mss4 PF04421.13 EGO19843.1 - 3.6e-13 49.4 0.0 4.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein Sec_GG PF07549.14 EGO19846.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif KDZ PF18758.1 EGO19847.1 - 0.0064 16.1 2.0 0.024 14.2 2.0 1.8 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Globin PF00042.22 EGO19849.1 - 0.025 15.1 1.2 0.036 14.6 0.3 1.6 2 0 0 2 2 2 0 Globin TPD52 PF04201.15 EGO19850.1 - 0.0034 17.0 3.6 0.91 9.1 0.0 2.4 2 0 0 2 2 2 2 Tumour protein D52 family PEARLI-4 PF05278.12 EGO19850.1 - 0.023 14.3 0.1 0.023 14.3 0.1 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) HIP1_clath_bdg PF16515.5 EGO19850.1 - 0.023 15.3 8.4 0.056 14.1 0.5 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF641 PF04859.12 EGO19850.1 - 0.047 14.0 3.6 0.84 10.0 0.1 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) EVI2A PF05399.11 EGO19850.1 - 0.052 13.1 0.0 0.052 13.1 0.0 3.2 2 1 1 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) COG2 PF06148.11 EGO19850.1 - 1.4 9.0 6.4 9.7 6.3 0.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Csm1_N PF18504.1 EGO19850.1 - 1.6 9.1 8.9 1.1 9.7 2.7 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain KxDL PF10241.9 EGO19850.1 - 2.8 8.3 7.1 2.8 8.3 1.5 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein Fez1 PF06818.15 EGO19850.1 - 9.9 6.6 20.5 1.8e+04 -5.9 20.5 2.5 1 1 0 1 1 1 0 Fez1 Acetyltransf_1 PF00583.25 EGO19851.1 - 8.8e-07 29.2 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO19851.1 - 8.2e-06 26.2 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO19851.1 - 4e-05 23.6 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDH-cyt PF16010.5 EGO19852.1 - 1.3e-49 168.4 2.0 1.3e-49 168.4 2.0 1.8 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EGO19852.1 - 7e-21 74.9 0.0 1.7e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO19852.1 - 1.8e-18 67.4 0.0 1.5e-17 64.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO19852.1 - 6.6e-07 28.8 0.3 3.9e-05 22.9 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGO19852.1 - 8.5e-06 25.4 0.1 8.4e-05 22.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO19852.1 - 4e-05 23.8 0.1 0.00014 22.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO19852.1 - 0.0001 21.7 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO19852.1 - 0.00014 20.7 0.1 0.00026 19.8 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGO19852.1 - 0.00022 20.9 0.1 0.0023 17.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO19852.1 - 0.00031 20.1 0.4 0.00062 19.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO19852.1 - 0.0013 18.0 0.0 0.022 14.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EGO19852.1 - 0.0017 17.6 0.3 0.02 14.2 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO19852.1 - 0.08 12.0 0.2 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGO19852.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Ras PF00071.22 EGO19853.1 - 4.5e-34 117.4 0.3 5.4e-34 117.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO19853.1 - 1.8e-25 89.5 0.3 4.1e-25 88.3 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO19853.1 - 7.9e-08 32.0 0.1 9.8e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO19853.1 - 5.4e-07 29.2 0.2 7e-07 28.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGO19853.1 - 0.0094 15.1 0.7 0.12 11.5 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit DLIC PF05783.11 EGO19853.1 - 0.013 14.3 1.1 1.5 7.5 0.0 2.4 1 1 2 3 3 3 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 EGO19853.1 - 0.014 14.8 0.0 1.8 8.0 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 EGO19853.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_18 PF00704.28 EGO19854.1 - 1.5e-76 258.1 8.0 2e-76 257.7 8.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EGO19854.1 - 1.9e-05 24.9 8.5 7.5e-05 23.1 8.5 2.1 1 0 0 1 1 1 1 Carbohydrate binding domain GramPos_pilinBB PF16569.5 EGO19854.1 - 0.27 12.0 2.0 0.51 11.2 0.0 2.2 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain Pkinase PF00069.25 EGO19855.1 - 5.3e-72 242.3 0.0 6.6e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19855.1 - 6.2e-35 120.7 0.0 8.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGO19855.1 - 6.3e-13 49.2 2.9 1.3e-12 48.3 2.9 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGO19855.1 - 1.3e-05 24.3 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO19855.1 - 0.0012 18.2 0.0 0.0032 16.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGO19855.1 - 0.057 13.0 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGO19855.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGO19855.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EAV_GS PF01309.18 EGO19856.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein PAP_assoc PF03828.19 EGO19857.1 - 1.8e-05 24.9 0.0 0.0023 18.1 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 EGO19857.1 - 0.0072 16.6 0.1 0.029 14.6 0.1 1.9 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain Paf67 PF10255.9 EGO19859.1 - 1.8e-167 557.4 0.0 2.3e-167 557.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ANAPC3 PF12895.7 EGO19859.1 - 0.035 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGO19859.1 - 0.08 13.1 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SNARE PF05739.19 EGO19861.1 - 6e-08 32.6 1.2 6e-08 32.6 1.2 2.2 2 0 0 2 2 2 1 SNARE domain DUF5435 PF17503.2 EGO19861.1 - 0.034 13.9 0.1 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5435) DUF3712 PF12505.8 EGO19861.1 - 0.074 13.3 0.1 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3712) Flp1_like PF16982.5 EGO19861.1 - 0.093 12.1 6.6 0.17 11.3 6.6 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Fusion_gly PF00523.18 EGO19861.1 - 0.11 10.7 0.5 0.16 10.2 0.5 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 GATase PF00117.28 EGO19863.1 - 1.9e-10 40.8 0.0 4.4e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EGO19863.1 - 0.024 14.5 0.0 0.087 12.7 0.0 1.7 1 1 0 1 1 1 0 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 EGO19863.1 - 0.039 13.7 0.3 0.16 11.7 0.1 1.9 2 1 0 3 3 3 0 Peptidase C26 p450 PF00067.22 EGO19864.1 - 1.2e-61 208.9 0.0 1.5e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.21 EGO19867.1 - 5.4e-23 81.7 0.0 1.9e-22 79.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO19867.1 - 7e-15 55.3 0.0 3.2e-13 49.8 0.0 2.8 2 2 1 3 3 3 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO19867.1 - 5.5e-09 35.4 0.0 7.9e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EGO19867.1 - 5.6e-06 25.9 0.0 8.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EGO19867.1 - 1.3e-05 24.5 0.1 0.0016 17.6 0.3 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGO19867.1 - 2.6e-05 23.5 0.1 0.00095 18.4 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EGO19867.1 - 3.1e-05 23.2 0.0 4.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGO19867.1 - 3.4e-05 23.8 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO19867.1 - 0.1 12.5 0.4 0.67 9.8 0.4 2.1 1 1 0 1 1 1 0 KR domain CUE PF02845.16 EGO19868.1 - 2.4e-11 43.1 0.1 4.5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 CUE domain ssDBP PF17878.1 EGO19870.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Single-stranded DNA-binding protein GCP_N_terminal PF17681.1 EGO19871.1 - 7e-64 216.4 0.0 1.6e-63 215.2 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGO19871.1 - 2.7e-60 204.4 8.4 2.7e-60 204.4 8.4 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal S4 PF01479.25 EGO19872.1 - 1.1e-09 37.8 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EGO19872.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ferric_reduct PF01794.19 EGO19873.1 - 8.6e-20 71.1 6.0 1.6e-19 70.2 6.0 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGO19873.1 - 1.1e-11 44.7 0.0 2.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGO19873.1 - 3.5e-11 43.5 0.0 1.5e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain PAXNEB PF05625.11 EGO19874.1 - 5.7e-45 154.0 0.0 2.6e-41 142.0 0.0 2.1 1 1 1 2 2 2 2 PAXNEB protein GST_N_3 PF13417.6 EGO19875.1 - 7.1e-15 55.2 0.3 2.9e-14 53.2 0.3 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO19875.1 - 5.3e-10 39.5 0.1 9.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO19875.1 - 3.6e-05 23.7 0.0 9.2e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO19875.1 - 0.00075 19.7 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGO19875.1 - 0.0041 17.8 0.0 0.0096 16.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGO19875.1 - 0.0044 17.3 0.0 0.0071 16.6 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGO19875.1 - 0.0067 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO19875.1 - 0.015 15.6 0.0 0.2 12.0 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO19875.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain STE3 PF02076.15 EGO19876.1 - 3.5e-91 305.4 20.0 4.2e-91 305.1 20.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor TMEM100 PF16311.5 EGO19876.1 - 0.0066 16.0 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 100 7TM_GPCR_Str PF10326.9 EGO19876.1 - 0.022 14.1 15.7 0.019 14.4 5.1 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str GST_N_3 PF13417.6 EGO19877.1 - 6.7e-16 58.5 0.1 1.2e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO19877.1 - 1.4e-10 41.3 0.2 2.5e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO19877.1 - 1.6e-05 25.0 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO19877.1 - 0.0054 16.9 0.0 0.0092 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGO19877.1 - 0.057 14.2 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 EGO19877.1 - 0.067 13.5 0.0 4 7.8 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO19877.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.11 EGO19878.1 - 2.8e-24 86.1 0.0 6.2e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EGO19879.1 - 3.7e-37 128.1 30.5 1.6e-31 109.5 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hist_rich_Ca-bd PF10529.9 EGO19879.1 - 1.5 9.1 3.1 3 8.2 3.1 1.5 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region MFS_1 PF07690.16 EGO19880.1 - 4.8e-51 173.7 61.1 5.1e-36 124.3 35.1 4.0 1 1 3 4 4 4 4 Major Facilitator Superfamily DUF3537 PF12056.8 EGO19880.1 - 0.0048 15.8 0.2 1.6 7.4 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3537) MscL PF01741.18 EGO19880.1 - 0.14 12.5 0.5 18 5.6 0.0 3.0 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL TM_helix PF05552.12 EGO19880.1 - 0.3 11.1 2.3 7.8 6.6 0.0 3.5 3 0 0 3 3 3 0 Conserved TM helix DUF2663 PF10864.8 EGO19880.1 - 0.53 10.7 6.3 23 5.4 0.0 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF2663) DUF4179 PF13786.6 EGO19880.1 - 1.3 9.5 3.0 57 4.3 0.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) MFS_1 PF07690.16 EGO19881.1 - 8e-31 107.2 32.1 4.3e-28 98.3 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_1 PF00190.22 EGO19882.1 - 3.5e-40 137.1 0.0 2.7e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGO19882.1 - 1.4e-22 79.2 3.6 1.8e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGO19882.1 - 1.8e-07 30.7 0.0 0.018 14.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EGO19882.1 - 0.00015 21.7 0.9 0.025 14.5 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.14 EGO19882.1 - 0.074 13.2 0.1 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family FA_desaturase PF00487.24 EGO19883.1 - 6.6e-16 58.9 23.8 6.6e-16 58.9 23.8 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGO19883.1 - 7e-12 45.3 0.0 2.4e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain SGL PF08450.12 EGO19884.1 - 6.4e-24 84.9 0.0 1.2e-23 84.0 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EGO19884.1 - 2.2e-05 24.5 0.0 0.00021 21.4 0.0 2.4 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EGO19884.1 - 0.003 17.7 0.0 0.033 14.4 0.0 2.6 2 0 0 2 2 2 1 Arylesterase LapA_dom PF06305.11 EGO19885.1 - 0.0012 18.6 4.6 0.24 11.2 0.1 2.6 3 0 0 3 3 3 2 Lipopolysaccharide assembly protein A domain DUF3169 PF11368.8 EGO19885.1 - 0.042 13.4 0.3 0.51 9.8 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) FtsX PF02687.21 EGO19885.1 - 0.3 11.6 9.5 1.7 9.1 4.7 2.6 1 1 1 2 2 2 0 FtsX-like permease family DUF4131 PF13567.6 EGO19885.1 - 2.1 8.0 6.1 5.2 6.7 3.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.15 EGO19885.1 - 4.7 7.7 11.5 2.9 8.4 3.2 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF202) DUF983 PF06170.12 EGO19885.1 - 9.8 6.7 8.2 0.46 10.9 1.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF983) L51_S25_CI-B8 PF05047.16 EGO19886.1 - 1.8e-14 53.4 0.0 2.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 EGO19886.1 - 0.032 13.5 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain RE_XcyI PF09571.10 EGO19886.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 XcyI restriction endonuclease RGS PF00615.19 EGO19887.1 - 3.7e-08 33.6 1.4 0.0014 18.9 0.2 2.4 2 1 0 2 2 2 2 Regulator of G protein signaling domain AMP-binding PF00501.28 EGO19888.1 - 3.7e-69 233.3 0.0 7.2e-69 232.4 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO19888.1 - 7e-19 68.6 0.1 1.6e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 EGO19889.1 - 1e-41 142.6 0.0 1.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO19889.1 - 1.9e-27 96.3 0.0 2.5e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO19889.1 - 7e-11 42.4 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO19889.1 - 4.2e-07 30.0 0.0 7.2e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO19889.1 - 0.0008 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO19889.1 - 0.0037 16.7 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO19889.1 - 0.027 13.6 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGO19889.1 - 0.028 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EGO19889.1 - 0.036 13.6 0.1 0.15 11.6 0.0 1.9 2 1 0 2 2 2 0 NmrA-like family HMG_box PF00505.19 EGO19890.1 - 3.1e-15 56.4 5.0 2.1e-08 34.5 0.2 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO19890.1 - 3e-10 40.5 0.8 4.2e-05 24.1 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain QRPTase_C PF01729.19 EGO19891.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF3255 PF11631.8 EGO19891.1 - 0.083 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) DUF463 PF04317.12 EGO19891.1 - 0.11 11.4 0.5 0.15 10.9 0.5 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 TMEM220 PF15071.6 EGO19892.1 - 6.6 7.5 7.4 3e+02 2.2 6.2 3.2 2 1 0 2 2 2 0 Transmembrane family 220, helix Rib_5-P_isom_A PF06026.14 EGO19894.1 - 2e-58 196.8 0.0 2.5e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) EPSP_synthase PF00275.20 EGO19895.1 - 7.1e-121 403.8 0.1 2.1e-120 402.2 0.0 1.7 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EGO19895.1 - 8e-100 333.3 0.5 1.4e-99 332.6 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EGO19895.1 - 3.3e-54 184.6 0.0 5.7e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EGO19895.1 - 3.7e-34 118.1 0.0 1.7e-32 112.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EGO19895.1 - 3.5e-25 88.1 0.0 1e-24 86.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGO19895.1 - 1.1e-07 31.5 0.5 3.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EGO19895.1 - 2.9e-07 30.5 0.1 7e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EGO19895.1 - 2.6e-05 24.3 0.0 7.9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 EGO19895.1 - 0.008 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO19895.1 - 0.043 14.2 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Pyr_redox_2 PF07992.14 EGO19896.1 - 2.1e-52 178.2 0.0 2.6e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO19896.1 - 7.8e-10 39.2 0.0 1.2e-08 35.3 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase BPS1 PF05633.11 EGO19896.1 - 0.019 14.0 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Pyr_redox_3 PF13738.6 EGO19896.1 - 0.046 13.0 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ferric_reduct PF01794.19 EGO19897.1 - 1.2e-20 73.9 7.1 1.2e-20 73.9 7.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGO19897.1 - 1e-12 48.1 0.0 2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGO19897.1 - 4.3e-08 33.4 0.0 2.9e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Cu-oxidase_4 PF02578.15 EGO19897.1 - 0.061 12.9 0.7 0.091 12.3 0.1 1.5 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase Glyco_hydro_12 PF01670.16 EGO19898.1 - 2e-32 113.0 11.7 2.3e-32 112.7 11.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PPV_E2_C PF00511.17 EGO19898.1 - 7.4 6.8 6.6 10 6.4 0.1 2.4 2 0 0 2 2 2 0 E2 (early) protein, C terminal Hid1 PF12722.7 EGO19899.1 - 3.7 5.5 5.0 4 5.4 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Transferase PF02458.15 EGO19900.1 - 1e-23 83.7 0.0 1.7e-18 66.5 0.0 2.0 2 0 0 2 2 2 2 Transferase family rve PF00665.26 EGO19900.1 - 0.2 11.9 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain DUF1744 PF08490.12 EGO19905.1 - 2.1e-135 451.4 0.0 3.2e-135 450.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGO19905.1 - 6.1e-72 242.6 0.0 1e-71 241.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGO19905.1 - 1.5e-11 43.7 0.2 2.6e-08 33.0 0.0 3.6 3 2 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGO19905.1 - 9.2e-07 28.8 0.6 6.9e-06 25.9 0.6 2.2 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGO19905.1 - 0.00053 20.0 0.0 0.0024 17.9 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily Toxin_28 PF08115.11 EGO19905.1 - 0.11 12.4 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 SFI toxin family MAP65_ASE1 PF03999.12 EGO19906.1 - 7.7e-65 219.8 2.6 1.4e-60 205.7 0.1 2.6 2 1 1 3 3 3 3 Microtubule associated protein (MAP65/ASE1 family) Exonuc_VII_L PF02601.15 EGO19906.1 - 0.43 10.1 6.9 0.84 9.1 0.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Hydantoinase_B PF02538.14 EGO19908.1 - 8.9e-212 704.1 0.1 1e-211 703.9 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase PHD PF00628.29 EGO19909.1 - 5.1e-07 29.5 0.9 5.1e-07 29.5 0.9 4.2 4 1 1 5 5 5 1 PHD-finger RdRP_5 PF07925.11 EGO19910.1 - 0.026 11.9 0.1 0.028 11.8 0.1 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 EF_assoc_2 PF08356.12 EGO19910.1 - 0.038 14.0 0.1 5.8 7.0 0.0 2.2 1 1 1 2 2 2 0 EF hand associated CGGC PF08821.11 EGO19911.1 - 0.0036 17.5 0.6 0.72 10.1 0.0 2.3 2 0 0 2 2 2 2 CGGC domain DUF4027 PF13219.6 EGO19912.1 - 0.15 11.9 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Acyl-CoA_dh_1 PF00441.24 EGO19913.1 - 0.0025 18.1 0.4 0.0039 17.4 0.0 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 EGO19914.1 - 3.9e-16 58.9 52.0 1.7e-14 53.5 41.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO19914.1 - 4.1 6.2 30.3 0.12 11.2 2.1 3.2 2 1 1 3 3 3 0 Sugar (and other) transporter FAD-oxidase_C PF02913.19 EGO19916.1 - 1.2e-47 162.7 0.0 2.8e-47 161.5 0.0 1.6 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO19916.1 - 8.1e-28 96.9 0.2 1.2e-27 96.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAR1 PF03101.15 EGO19917.1 - 0.078 13.7 0.1 0.092 13.5 0.1 1.1 1 0 0 1 1 1 0 FAR1 DNA-binding domain FAD_binding_3 PF01494.19 EGO19919.1 - 3.5e-16 59.4 0.0 8.5e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO19919.1 - 2.8e-07 30.4 1.7 0.00031 20.4 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO19919.1 - 9.7e-07 28.3 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO19919.1 - 9.9e-07 28.9 0.2 2.7e-06 27.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO19919.1 - 1.6e-05 24.2 0.1 4.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EGO19919.1 - 2.9e-05 23.5 0.2 0.013 14.8 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EGO19919.1 - 0.00035 21.1 0.0 0.009 16.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO19919.1 - 0.0027 16.8 0.7 1.1 8.2 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 EGO19919.1 - 0.0033 16.2 0.0 0.044 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGO19919.1 - 0.008 15.5 0.0 0.031 13.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO19919.1 - 0.072 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EGO19919.1 - 0.093 11.6 0.0 9.1 5.0 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase TetR_C_13 PF16925.5 EGO19919.1 - 0.23 11.4 0.9 0.45 10.5 0.9 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HIG_1_N PF04588.13 EGO19920.1 - 7e-05 23.0 0.6 0.00014 22.0 0.6 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PGM1_C PF18105.1 EGO19920.1 - 0.088 12.3 0.2 2 8.0 0.1 2.5 2 0 0 2 2 2 0 PGM1 C-terminal domain DUF3859 PF12975.7 EGO19920.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3859) Nfu_N PF08712.11 EGO19922.1 - 0.17 12.0 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal EF-hand_1 PF00036.32 EGO19923.1 - 5.2e-43 141.4 12.2 4.3e-10 38.4 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO19923.1 - 1.9e-36 124.4 2.8 1.2e-18 67.3 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGO19923.1 - 9.9e-33 111.8 10.9 1.8e-13 50.1 0.6 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGO19923.1 - 1e-31 106.1 6.8 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGO19923.1 - 1.1e-27 94.2 8.5 1.6e-06 27.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGO19923.1 - 8.1e-17 61.3 0.3 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGO19923.1 - 3.2e-10 39.9 0.7 8e-05 22.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGO19923.1 - 1.3e-08 35.2 0.0 0.0013 19.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGO19923.1 - 5.1e-06 27.3 0.0 0.0033 18.3 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EGO19923.1 - 5.3e-06 26.4 0.1 0.042 13.9 0.0 3.3 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGO19923.1 - 6.8e-05 22.9 1.0 0.00031 20.8 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EGO19923.1 - 0.00028 21.0 5.6 0.034 14.3 0.9 3.0 1 1 3 4 4 4 2 Dockerin type I domain DUF1103 PF06513.11 EGO19923.1 - 0.00033 20.4 1.2 0.00038 20.2 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 EGO19923.1 - 0.00033 20.6 0.4 0.4 10.6 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF4497 PF14924.6 EGO19923.1 - 0.0013 19.1 0.0 0.47 10.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) DUF3349 PF11829.8 EGO19923.1 - 0.0016 19.1 0.2 1.5 9.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Poly_export PF02563.16 EGO19923.1 - 0.0027 17.9 0.1 0.44 10.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 EGO19923.1 - 0.0038 17.3 0.5 0.057 13.6 0.1 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF5580 PF17743.1 EGO19923.1 - 0.0044 15.6 0.0 0.0044 15.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 EGO19923.1 - 0.0056 17.0 0.5 3.4 8.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 EGO19923.1 - 0.0064 16.5 0.2 0.5 10.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 EGO19923.1 - 0.0098 16.2 0.1 4.8 7.6 0.0 2.4 1 1 0 2 2 2 1 EF-hand domain SurA_N_2 PF13623.6 EGO19923.1 - 0.02 14.8 0.5 1.3 8.9 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 EGO19923.1 - 0.052 13.2 0.3 0.098 12.3 0.3 1.6 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF1811 PF08838.10 EGO19923.1 - 0.063 13.5 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Spore_III_AB PF09548.10 EGO19923.1 - 0.066 13.3 0.3 0.14 12.3 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FGAR-AT_linker PF18072.1 EGO19923.1 - 0.078 13.5 0.2 7.1 7.3 0.0 2.6 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain dCache_2 PF08269.11 EGO19923.1 - 0.081 12.1 0.2 7.1 5.7 0.1 2.3 1 1 0 2 2 2 0 Cache domain Pkinase PF00069.25 EGO19924.1 - 3.7e-68 229.7 0.0 4.9e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19924.1 - 1.7e-39 135.7 0.0 2.4e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO19924.1 - 8.1e-10 38.5 0.0 1.8e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO19924.1 - 0.0034 16.8 0.2 0.0064 15.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO19924.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Synaptobrevin PF00957.21 EGO19925.1 - 1e-33 114.9 3.2 1.2e-33 114.8 3.2 1.0 1 0 0 1 1 1 1 Synaptobrevin Peptidase_M48_N PF16491.5 EGO19925.1 - 0.0056 16.6 0.4 0.0074 16.2 0.4 1.1 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices DUF515 PF04415.12 EGO19925.1 - 0.041 12.3 1.6 0.067 11.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Acetyltransf_1 PF00583.25 EGO19926.1 - 8.9e-11 42.1 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO19926.1 - 5.7e-09 36.3 0.0 8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO19926.1 - 1.7e-08 34.5 0.0 2.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO19926.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Chitin_synth_2 PF03142.15 EGO19927.1 - 1.7e-67 228.2 1.5 1.1e-65 222.3 1.1 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO19927.1 - 0.023 14.6 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 TSC22 PF01166.18 EGO19927.1 - 0.072 13.4 0.5 0.15 12.4 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Plavaka PF18759.1 EGO19929.1 - 6.4e-46 157.1 0.0 1.1e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Mo25 PF08569.11 EGO19930.1 - 2.6e-133 444.4 5.6 2.9e-133 444.3 5.6 1.0 1 0 0 1 1 1 1 Mo25-like F-box PF00646.33 EGO19931.1 - 4.5e-06 26.4 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO19931.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like NfI_DNAbd_pre-N PF10524.9 EGO19931.1 - 0.097 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Pkinase PF00069.25 EGO19932.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19932.1 - 0.00064 19.1 0.0 0.00071 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.27 EGO19934.1 - 1.2e-52 175.8 0.7 2.4e-16 59.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp PF00026.23 EGO19935.1 - 1.4e-31 110.1 0.0 2e-14 53.7 1.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO19935.1 - 0.017 15.4 1.8 2.4 8.4 0.7 3.3 3 1 0 3 3 3 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO19935.1 - 0.044 14.4 0.4 3.7 8.3 0.2 3.3 2 1 0 2 2 2 0 Aspartyl protease Fungal_trans PF04082.18 EGO19936.1 - 1.1e-22 80.4 0.0 2.6e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO19936.1 - 7.8e-10 38.7 11.0 1.6e-09 37.7 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 EGO19938.1 - 3.5e-16 59.9 0.0 3.6e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family F-box-like PF12937.7 EGO19940.1 - 8.8e-09 35.1 0.2 3.6e-08 33.2 0.2 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGO19940.1 - 0.092 13.2 4.7 3.4 8.2 0.0 4.3 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO19940.1 - 0.28 11.0 3.9 1.5 8.7 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat PhoLip_ATPase_C PF16212.5 EGO19941.1 - 2.1e-74 250.5 29.1 2.1e-74 250.5 29.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO19941.1 - 1.2e-21 76.2 0.2 3e-21 74.9 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGO19941.1 - 9.6e-12 44.8 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO19941.1 - 1.1e-10 42.2 0.4 0.00014 22.2 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO19941.1 - 8.6e-07 28.7 8.4 9.7e-07 28.5 0.3 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGO19941.1 - 0.0038 17.0 0.1 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4728 PF15860.5 EGO19941.1 - 4.8 7.9 10.1 8.8 7.1 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) ABC_tran PF00005.27 EGO19942.1 - 6.9e-51 172.4 0.0 6.2e-29 101.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO19942.1 - 2.9e-50 171.4 11.5 6.4e-30 104.7 3.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO19942.1 - 1.2e-09 37.9 4.4 0.0033 16.9 0.2 4.3 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO19942.1 - 1.4e-07 31.1 2.3 0.00092 18.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EGO19942.1 - 4.8e-06 25.8 0.3 0.077 12.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 EGO19942.1 - 8.1e-06 26.5 0.7 0.0011 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO19942.1 - 2.8e-05 24.6 4.2 0.23 11.8 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.17 EGO19942.1 - 3.2e-05 24.1 2.1 0.0077 16.4 0.2 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EGO19942.1 - 6e-05 23.3 0.6 0.69 10.2 0.2 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGO19942.1 - 0.00012 22.2 0.1 0.28 11.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EGO19942.1 - 0.00058 19.5 3.6 0.4 10.2 0.0 3.5 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 EGO19942.1 - 0.00069 19.5 0.2 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DUF2075 PF09848.9 EGO19942.1 - 0.0018 17.5 1.5 0.38 9.9 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EGO19942.1 - 0.0021 17.4 0.3 0.26 10.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EGO19942.1 - 0.0037 17.8 0.2 3.6 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO19942.1 - 0.0053 16.3 0.3 3.1 7.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EGO19942.1 - 0.0067 15.4 1.3 0.39 9.6 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 EGO19942.1 - 0.0072 15.7 0.2 3.3 7.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.12 EGO19942.1 - 0.0097 15.8 1.3 1.7 8.6 0.1 2.6 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 EGO19942.1 - 0.014 15.1 0.0 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 EGO19942.1 - 0.023 14.5 3.4 0.71 9.6 0.2 3.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGO19942.1 - 0.039 13.7 0.2 9 6.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGO19942.1 - 0.053 13.6 1.9 4 7.5 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Herpes_Helicase PF02689.14 EGO19942.1 - 0.062 11.2 0.0 0.2 9.5 0.0 1.7 2 0 0 2 2 2 0 Helicase CbiA PF01656.23 EGO19942.1 - 0.079 13.0 0.0 13 5.9 0.0 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 EGO19942.1 - 0.082 12.9 1.2 6.9 6.7 0.1 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EGO19942.1 - 0.09 12.0 0.7 2 7.6 0.1 2.7 2 1 0 2 2 2 0 NB-ARC domain FKBP_N_2 PF18023.1 EGO19942.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BDBT FKBP like N-terminal cobW PF02492.19 EGO19942.1 - 0.12 12.0 1.8 4.7 6.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGO19942.1 - 0.13 12.7 0.0 9.8 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EGO19942.1 - 0.14 12.3 0.3 5.6 7.1 0.2 2.8 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGO19942.1 - 2.1 8.2 3.7 12 5.8 0.1 2.9 3 0 0 3 3 3 0 NTPase NAD_binding_4 PF07993.12 EGO19943.1 - 2.1e-31 109.1 0.0 3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO19943.1 - 1.3e-20 73.4 0.0 1.2e-13 50.4 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 EGO19943.1 - 0.0028 17.2 0.0 0.0072 15.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO19943.1 - 0.018 15.4 0.2 0.11 12.9 0.2 2.2 1 1 0 1 1 1 0 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 EGO19943.1 - 0.07 13.0 0.0 0.49 10.3 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding zf-CCHC_3 PF13917.6 EGO19944.1 - 1.1e-06 28.4 1.6 1.2e-06 28.4 1.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO19944.1 - 2.6e-06 27.3 5.0 3.3e-06 26.9 5.0 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO19944.1 - 0.016 14.7 0.9 0.023 14.2 0.9 1.3 1 0 0 1 1 1 0 Copper fist DNA binding domain Methyltransf_25 PF13649.6 EGO19947.1 - 5.3e-07 30.3 0.0 1.1e-06 29.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO19947.1 - 9.9e-06 25.4 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO19947.1 - 8.1e-05 23.2 0.0 0.00014 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO19947.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Aldedh PF00171.22 EGO19950.1 - 1.5e-82 277.6 0.0 1.8e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO19950.1 - 0.0031 16.6 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short_C2 PF13561.6 EGO19951.1 - 6.3e-53 179.7 6.4 3e-52 177.5 6.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO19951.1 - 5.6e-48 163.0 3.7 7.6e-48 162.6 3.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO19951.1 - 1.4e-11 44.6 2.3 2e-11 44.2 2.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO19951.1 - 0.031 13.8 0.3 0.04 13.4 0.3 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELL PF10390.9 EGO19953.1 - 0.37 10.2 1.7 0.58 9.6 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Pyr_redox_2 PF07992.14 EGO19954.1 - 8.6e-66 222.1 8.5 1e-65 221.9 7.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGO19954.1 - 4.4e-42 142.8 4.7 4.8e-42 142.7 0.2 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGO19954.1 - 3.1e-22 78.9 8.1 1.9e-19 70.0 2.7 3.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO19954.1 - 3.6e-10 39.5 9.3 3.7e-10 39.4 0.8 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGO19954.1 - 8.2e-10 38.6 0.3 8.2e-10 38.6 0.3 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO19954.1 - 3.4e-09 36.4 10.7 1.5e-06 27.7 1.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO19954.1 - 3.8e-09 36.6 3.3 3e-05 24.1 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO19954.1 - 1.5e-06 27.6 2.4 1.5e-06 27.6 2.4 3.3 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.14 EGO19954.1 - 7.2e-06 25.0 15.7 0.00045 19.0 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 EGO19954.1 - 5.2e-05 22.6 2.1 0.021 14.0 0.1 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EGO19954.1 - 0.00019 20.8 7.8 0.011 15.0 0.6 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EGO19954.1 - 0.00022 20.5 5.6 0.0013 18.0 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGO19954.1 - 0.00055 19.3 11.6 0.039 13.2 0.5 3.9 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 EGO19954.1 - 0.0014 18.3 15.7 0.52 9.8 0.2 4.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO19954.1 - 0.12 12.4 2.6 8.6 6.3 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGO19954.1 - 3.2 6.7 7.9 1.1 8.2 0.5 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein Pkinase PF00069.25 EGO19956.1 - 1.2e-30 106.8 0.0 8e-30 104.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO19956.1 - 9.6e-08 31.6 0.0 3.3e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO19956.1 - 0.0003 20.2 0.0 0.065 12.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGO19956.1 - 0.00055 19.9 0.7 0.0011 19.0 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO19956.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCRA PF06100.11 EGO19956.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 MCRA family Lge1 PF11488.8 EGO19958.1 - 0.036 14.2 0.3 2.2 8.5 0.2 3.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 CdAMP_rec PF06153.11 EGO19958.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Cyclic-di-AMP receptor HMMR_C PF15908.5 EGO19958.1 - 0.23 11.7 9.8 0.068 13.4 1.4 3.0 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal DUF5082 PF16888.5 EGO19958.1 - 0.23 11.8 15.4 2.9 8.2 5.6 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) DUF4047 PF13256.6 EGO19958.1 - 0.27 11.4 1.9 1.2 9.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Atg14 PF10186.9 EGO19958.1 - 0.46 9.5 17.9 0.21 10.7 4.6 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 EGO19958.1 - 0.95 8.9 16.4 0.097 12.1 7.1 2.5 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HIP1_clath_bdg PF16515.5 EGO19958.1 - 2.1 9.0 18.6 7.1 7.3 3.2 4.0 2 2 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 EGO19958.1 - 2.4 8.4 20.3 1.4 9.2 4.6 3.8 1 1 3 4 4 4 0 Tho complex subunit 7 CENP-F_leu_zip PF10473.9 EGO19958.1 - 6.6 6.8 25.2 3.6 7.6 4.5 3.3 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 EGO19958.1 - 6.7 7.4 19.5 4.6 7.9 1.7 5.1 5 0 0 5 5 5 0 SlyX Cep57_CLD_2 PF14197.6 EGO19958.1 - 7.4 6.8 15.6 36 4.6 0.5 4.9 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 EGO19958.1 - 8.8 6.7 32.6 2.6 8.5 11.3 3.3 2 1 2 4 4 4 0 Fez1 MARVEL PF01284.23 EGO19959.1 - 0.01 15.9 11.2 0.053 13.5 7.0 2.2 2 0 0 2 2 2 0 Membrane-associating domain Lig_chan PF00060.26 EGO19959.1 - 0.024 14.5 1.6 0.15 11.9 1.6 2.2 1 1 0 1 1 1 0 Ligand-gated ion channel DUF4293 PF14126.6 EGO19959.1 - 0.047 13.9 7.9 0.019 15.2 5.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF202 PF02656.15 EGO19959.1 - 0.22 12.0 9.7 0.13 12.7 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) UPF0114 PF03350.16 EGO19961.1 - 3.6 7.8 9.6 0.1 12.8 2.6 2.0 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 DPBB_1 PF03330.18 EGO19964.1 - 3.5e-07 30.4 0.0 7.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 EGO19964.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EGO19964.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Barwin family DPBB_1 PF03330.18 EGO19965.1 - 4.8e-10 39.6 0.7 9.1e-10 38.7 0.7 1.6 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 EGO19965.1 - 0.0039 17.3 0.4 0.005 17.0 0.4 1.4 1 1 0 1 1 1 1 Cerato-platanin DUF4971 PF16341.5 EGO19965.1 - 0.082 12.7 0.1 0.098 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) TPR_2 PF07719.17 EGO19967.1 - 1.5e-05 24.8 1.8 0.14 12.4 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO19967.1 - 1.5e-05 24.6 5.4 0.00092 18.8 1.5 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 EGO19967.1 - 0.0017 18.1 2.8 0.94 9.4 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO19967.1 - 0.023 15.1 0.1 7.1 7.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Suc_Fer-like PF06999.12 EGO19968.1 - 6.8e-30 104.4 0.0 7.5e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like ACR_tran PF00873.19 EGO19968.1 - 0.0071 14.1 0.0 0.0094 13.7 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Lactonase PF10282.9 EGO19969.1 - 4.1e-33 115.1 0.0 4.7e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller zf-RING_2 PF13639.6 EGO19970.1 - 0.00029 21.1 14.8 0.00059 20.1 14.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO19970.1 - 0.0045 16.9 13.1 0.0094 15.9 13.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO19970.1 - 0.0048 16.7 13.2 0.0098 15.7 13.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO19970.1 - 0.0054 16.6 14.4 0.01 15.7 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Methyltrans_Mon PF14314.6 EGO19970.1 - 0.019 13.0 0.2 0.025 12.6 0.2 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase Csm1_N PF18504.1 EGO19970.1 - 0.02 15.2 1.8 0.02 15.2 1.8 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain zf-RING_UBOX PF13445.6 EGO19970.1 - 0.04 14.0 14.8 0.13 12.3 10.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 EGO19970.1 - 0.048 13.5 9.0 0.094 12.5 9.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Spc29 PF17082.5 EGO19970.1 - 0.36 10.6 4.3 1.1 9.1 4.3 1.9 1 1 0 1 1 1 0 Spindle Pole Component 29 OmpH PF03938.14 EGO19970.1 - 1.1 9.5 5.3 0.32 11.3 1.8 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-RING_10 PF16685.5 EGO19970.1 - 1.2 9.3 8.5 2.8 8.1 8.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 EGO19970.1 - 1.4 8.9 11.3 0.21 11.5 5.6 2.2 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) KfrA_N PF11740.8 EGO19970.1 - 1.8 9.3 8.4 0.44 11.2 4.5 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term TMF_DNA_bd PF12329.8 EGO19970.1 - 2.1 8.4 8.4 2 8.4 1.5 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-C3HC4_4 PF15227.6 EGO19970.1 - 2.4 8.4 14.6 5.3 7.3 14.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGO19970.1 - 5.8 6.9 14.5 13 5.7 14.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SOGA PF11365.8 EGO19970.1 - 6.8 7.9 9.0 5.5e+02 1.8 8.1 3.0 1 1 1 2 2 2 0 Protein SOGA FYVE PF01363.21 EGO19970.1 - 9.2 6.5 13.2 23 5.2 11.1 2.6 2 1 1 3 3 3 0 FYVE zinc finger HTH_31 PF13560.6 EGO19971.1 - 0.0001 22.6 0.1 0.00017 21.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EGO19971.1 - 0.00039 20.4 0.1 0.00066 19.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.12 EGO19971.1 - 0.033 13.9 0.6 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 EGO19971.1 - 0.064 13.1 0.2 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_19 PF12844.7 EGO19971.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S11 PF00411.19 EGO19972.1 - 1.8e-46 157.1 1.4 2.2e-46 156.8 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EGO19972.1 - 0.087 13.1 0.1 0.18 12.1 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Acyltransferase PF01553.21 EGO19973.1 - 1.2e-13 50.8 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zf-RING_2 PF13639.6 EGO19976.1 - 2.3e-09 37.4 7.2 4.1e-09 36.6 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO19976.1 - 3.5e-08 33.3 3.7 3.7e-08 33.2 2.1 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO19976.1 - 6.4e-08 32.4 7.5 1e-07 31.8 7.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGO19976.1 - 2e-07 30.7 5.1 3.4e-07 30.0 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO19976.1 - 9.9e-07 28.5 6.0 2.4e-06 27.3 6.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO19976.1 - 2.4e-06 27.3 6.8 5.1e-06 26.3 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO19976.1 - 5.6e-06 26.1 7.4 9.6e-06 25.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO19976.1 - 0.00096 19.3 8.8 0.006 16.7 9.1 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGO19976.1 - 0.0025 18.1 5.1 0.0045 17.2 5.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain FYVE PF01363.21 EGO19976.1 - 0.0036 17.4 6.2 0.038 14.1 1.9 2.3 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_6 PF14835.6 EGO19976.1 - 0.0051 16.7 0.2 0.0051 16.7 0.2 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF1272 PF06906.11 EGO19976.1 - 0.0067 16.5 3.7 0.01 15.9 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EGO19976.1 - 0.015 15.0 4.3 0.015 15.0 4.3 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EGO19976.1 - 0.024 14.6 1.6 0.041 13.8 1.6 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Zf_RING PF16744.5 EGO19976.1 - 0.026 14.6 2.9 0.048 13.8 2.8 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger Pro_CA PF00484.19 EGO19976.1 - 0.031 14.6 0.4 0.037 14.3 0.4 1.3 1 1 0 1 1 1 0 Carbonic anhydrase zf-RING_10 PF16685.5 EGO19976.1 - 0.048 13.8 4.3 0.09 12.9 4.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 TruB_C_2 PF16198.5 EGO19976.1 - 0.068 13.3 0.2 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain zf-RING_11 PF17123.5 EGO19976.1 - 0.094 12.5 3.0 0.098 12.4 1.2 2.0 1 1 1 2 2 2 0 RING-like zinc finger Rtf2 PF04641.12 EGO19976.1 - 0.14 11.5 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zinc_ribbon_4 PF13717.6 EGO19976.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.4 3 0 0 3 3 2 0 zinc-ribbon domain zf-HIT PF04438.16 EGO19976.1 - 0.78 9.7 5.7 1.3 9.0 2.8 2.3 2 0 0 2 2 2 0 HIT zinc finger FAM76 PF16046.5 EGO19976.1 - 1.5 8.1 5.1 1.6 8.0 2.8 1.9 1 1 1 2 2 2 0 FAM76 protein Synaptobrevin PF00957.21 EGO19978.1 - 2.8e-30 103.9 0.8 3.9e-30 103.5 0.8 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGO19978.1 - 5e-23 80.9 0.0 8.8e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain YwcE PF17368.2 EGO19978.1 - 0.011 16.4 0.3 0.025 15.3 0.3 1.5 1 0 0 1 1 1 0 Spore morphogenesis and germination YwcE HCMV_UL124 PF17609.2 EGO19978.1 - 0.069 13.3 0.5 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function Sec61_beta PF03911.16 EGO19979.1 - 3.5e-17 62.1 0.7 4.5e-17 61.8 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family DNA_pol_A_exo1 PF01612.20 EGO19980.1 - 5.2e-11 42.6 0.0 2.7e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Euplotes_phero PF05842.11 EGO19981.1 - 0.58 10.7 10.6 1.1 9.8 10.6 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Profilin PF00235.19 EGO19982.1 - 3.4e-46 156.6 0.8 3.8e-46 156.5 0.8 1.0 1 0 0 1 1 1 1 Profilin DDE_3 PF13358.6 EGO19984.1 - 0.00035 20.3 0.1 0.041 13.6 0.0 2.7 3 0 0 3 3 3 2 DDE superfamily endonuclease Cwf_Cwc_15 PF04889.12 EGO19985.1 - 0.73 9.5 12.7 2 8.1 12.7 1.8 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein V_ATPase_I PF01496.19 EGO19985.1 - 1.2 7.0 3.1 1.3 6.9 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family STE3 PF02076.15 EGO19986.1 - 1.6e-97 326.2 15.6 2e-97 325.9 15.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 EGO19986.1 - 0.13 12.1 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MBT PF02820.18 EGO19986.1 - 0.13 12.6 0.5 5.8 7.4 0.4 2.5 2 0 0 2 2 2 0 mbt repeat NACHT PF05729.12 EGO19987.1 - 2.4e-07 30.8 0.0 5e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGO19987.1 - 3.4e-07 30.6 0.0 7.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO19987.1 - 1.1e-05 25.9 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGO19987.1 - 0.00012 21.4 0.2 0.00022 20.5 0.2 1.4 1 1 0 1 1 1 1 NB-ARC domain ATPase PF06745.13 EGO19987.1 - 0.0029 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EGO19987.1 - 0.0034 17.0 0.1 0.008 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGO19987.1 - 0.008 16.6 0.2 0.042 14.3 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGO19987.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SQS_PSY PF00494.19 EGO19987.1 - 0.035 13.6 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase LIAS_N PF16881.5 EGO19987.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family CRM1_repeat_2 PF18784.1 EGO19987.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 AAA_19 PF13245.6 EGO19987.1 - 0.043 14.1 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGO19987.1 - 0.047 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRI PF08236.11 EGO19987.1 - 0.054 13.7 2.6 0.43 10.8 1.2 2.7 2 1 0 2 2 1 0 SRI (Set2 Rpb1 interacting) domain COX8 PF02285.15 EGO19987.1 - 0.056 13.3 0.3 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII RNA_helicase PF00910.22 EGO19987.1 - 0.067 13.6 0.1 0.38 11.2 0.0 2.1 1 1 0 2 2 2 0 RNA helicase FANCI_S4 PF14678.6 EGO19987.1 - 0.089 11.9 0.5 0.16 11.1 0.2 1.5 2 0 0 2 2 2 0 FANCI solenoid 4 cobW PF02492.19 EGO19987.1 - 0.11 12.0 0.0 0.83 9.2 0.0 2.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EGO19987.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EGO19987.1 - 0.13 12.9 0.1 0.48 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain FHA PF00498.26 EGO19990.1 - 2.6e-16 59.7 0.0 4.2e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EGO19990.1 - 4.2e-08 32.8 0.9 4.2e-08 32.8 0.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EGO19990.1 - 2.9e-07 30.7 1.3 2.9e-07 30.7 1.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO19990.1 - 8.2e-07 28.8 1.6 1.8e-06 27.7 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO19990.1 - 3.5e-06 26.8 3.8 7.5e-06 25.7 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGO19990.1 - 1.1e-05 25.4 0.1 2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGO19990.1 - 1.2e-05 25.5 4.1 2.3e-05 24.6 4.1 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGO19990.1 - 3e-05 23.9 0.4 3e-05 23.9 0.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 EGO19990.1 - 0.001 19.4 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 EGO19990.1 - 0.0069 16.3 0.7 0.0069 16.3 0.7 1.9 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_4 PF15227.6 EGO19990.1 - 0.022 14.9 1.4 0.046 13.9 1.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGO19990.1 - 0.033 14.0 0.8 0.033 14.0 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO19990.1 - 0.051 13.6 5.2 0.11 12.6 5.2 1.6 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO19990.1 - 0.55 10.1 7.8 1.3 9.0 7.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4655 PF15548.6 EGO19992.1 - 0.043 12.8 1.8 0.058 12.4 1.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4655) zf-CCHC PF00098.23 EGO19994.1 - 8.4e-08 31.9 1.2 1.2e-07 31.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO19994.1 - 0.0086 15.6 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCHC_6 PF15288.6 EGO19994.1 - 0.14 12.0 1.5 0.22 11.4 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_11 PF08241.12 EGO19995.1 - 7.7e-20 71.4 0.0 1.5e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO19995.1 - 1.4e-17 64.1 0.0 2.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO19995.1 - 7.5e-10 39.5 0.0 1.2e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO19995.1 - 1.6e-08 34.5 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO19995.1 - 9.3e-08 31.7 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO19995.1 - 1e-05 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO19995.1 - 0.00019 21.0 0.0 0.00042 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGO19995.1 - 0.15 11.9 0.0 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Fer2_3 PF13085.6 EGO19996.1 - 2.5e-31 107.9 0.0 3.7e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGO19996.1 - 1.8e-10 41.2 7.8 1.8e-10 41.2 7.8 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGO19996.1 - 1.4e-07 31.5 4.0 1.4e-07 31.5 4.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGO19996.1 - 1.3e-06 28.7 8.6 1.3e-06 28.7 8.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGO19996.1 - 0.0003 21.3 4.8 0.0003 21.3 4.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGO19996.1 - 0.003 17.5 3.4 0.0045 16.9 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EGO19996.1 - 0.2 11.9 4.0 0.59 10.3 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Abhydrolase_6 PF12697.7 EGO19997.1 - 2.9e-10 41.1 3.1 3.3e-10 40.9 3.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO19997.1 - 1.4e-07 31.1 0.5 3.3e-07 29.8 0.5 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO19997.1 - 1.5e-07 31.3 0.2 1.9e-07 31.0 0.2 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EGO19997.1 - 0.064 12.8 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 EGO19997.1 - 0.2 10.6 0.0 0.22 10.5 0.0 1.3 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 EGO19997.1 - 0.21 10.5 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme STE3 PF02076.15 EGO19998.1 - 2.5e-83 279.6 15.9 4.6e-48 163.9 0.1 2.1 1 1 1 2 2 2 2 Pheromone A receptor HET PF06985.11 EGO19999.1 - 1.3e-16 61.3 0.2 2.5e-16 60.3 0.2 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M14 PF00246.24 EGO20001.1 - 7.3e-69 232.7 0.0 9.1e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase NUC153 PF08159.12 EGO20002.1 - 1.3e-13 50.5 1.7 1.3e-13 50.5 1.7 5.0 5 1 0 5 5 5 2 NUC153 domain EBV-NA3 PF05009.12 EGO20002.1 - 0.45 10.0 4.6 7.3 6.0 0.4 2.5 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) AhpC-TSA PF00578.21 EGO20003.1 - 1.2e-25 89.8 0.0 1.6e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO20003.1 - 1.1e-17 64.2 0.0 1.6e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF3776 PF12618.8 EGO20003.1 - 0.15 12.6 11.9 0.31 11.6 8.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3776) LRR_6 PF13516.6 EGO20004.1 - 2.4e-15 55.2 16.5 0.15 12.2 0.3 9.4 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 EGO20004.1 - 5.5e-07 29.8 13.0 0.017 15.5 0.6 6.1 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO20004.1 - 0.0071 16.7 15.8 7.9 7.5 0.0 7.2 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 EGO20004.1 - 0.02 14.7 21.1 4.2 7.2 3.2 6.8 4 1 2 6 6 6 0 Leucine rich repeat GST_N_2 PF13409.6 EGO20005.1 - 3.2e-06 27.3 0.1 6.6e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO20005.1 - 9.3e-06 26.0 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO20005.1 - 0.035 14.3 0.0 0.095 12.9 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO20005.1 - 0.11 12.5 0.5 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ArAE_2_N PF10337.9 EGO20006.1 - 2.7e-59 201.5 0.0 3.3e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EGO20007.1 - 2.5e-29 102.8 0.3 3.6e-29 102.2 0.3 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EGO20007.1 - 1.8e-10 41.0 15.0 3.2e-10 40.2 15.0 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGO20007.1 - 0.00029 19.6 1.3 0.00043 19.0 1.3 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family Aldedh PF00171.22 EGO20009.1 - 1.5e-167 557.8 0.5 1.8e-167 557.6 0.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UvrD_C PF13361.6 EGO20010.1 - 9.9e-11 41.6 0.0 2.2e-08 33.9 0.0 3.4 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EGO20010.1 - 1.4e-06 28.0 0.2 0.0044 16.8 0.1 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EGO20010.1 - 2.2e-05 24.1 2.8 0.003 17.1 0.1 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGO20010.1 - 4.1e-05 23.9 0.0 0.00016 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGO20010.1 - 0.002 17.8 0.0 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO20010.1 - 0.0074 16.7 0.6 0.6 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain SNAP PF14938.6 EGO20010.1 - 0.016 14.7 5.0 0.031 13.7 5.0 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP AAA_22 PF13401.6 EGO20010.1 - 0.021 15.1 0.0 1.8 8.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO20010.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_2 PF07719.17 EGO20010.1 - 0.2 11.9 3.0 5.5 7.4 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EGO20011.1 - 5.2e-08 33.5 0.0 1.1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO20011.1 - 7.4e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO20011.1 - 1.8e-06 27.9 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGO20011.1 - 3e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGO20011.1 - 4.9e-05 23.9 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO20011.1 - 0.00012 22.7 0.0 0.00027 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO20011.1 - 0.00033 20.5 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGO20011.1 - 0.00078 20.4 0.0 0.0018 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGO20011.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.20 EGO20011.1 - 0.025 13.9 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EGO20011.1 - 0.055 13.6 0.0 0.067 13.3 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGO20011.1 - 0.057 13.2 0.2 0.25 11.1 0.2 1.9 1 1 0 1 1 1 0 Lysine methyltransferase PTR2 PF00854.21 EGO20012.1 - 8.3e-81 271.8 12.1 1.1e-80 271.5 12.1 1.1 1 0 0 1 1 1 1 POT family dsrm PF00035.26 EGO20013.1 - 1.3e-08 35.4 0.0 1.6e-08 35.1 0.0 1.3 1 1 0 1 1 1 1 Double-stranded RNA binding motif Abhydrolase_3 PF07859.13 EGO20015.1 - 7.8e-51 172.9 0.0 9.7e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO20015.1 - 0.0017 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_transf_15 PF01793.16 EGO20016.1 - 1.8e-114 382.4 12.0 2.1e-114 382.2 12.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIR2 PF02146.17 EGO20018.1 - 9.3e-35 120.1 0.0 2.4e-34 118.8 0.0 1.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGO20018.1 - 0.063 13.0 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 EGO20018.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Pex19 PF04614.12 EGO20019.1 - 6.5e-57 193.1 0.6 9.1e-57 192.6 0.6 1.2 1 0 0 1 1 1 1 Pex19 protein family CAP_N PF01213.19 EGO20019.1 - 0.006 16.1 0.9 0.011 15.2 0.9 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Lyase_8 PF02278.18 EGO20020.1 - 1e-67 228.4 2.4 1.7e-67 227.6 2.4 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 EGO20020.1 - 1.4e-16 60.4 0.1 2.3e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 EGO20020.1 - 1.6e-10 41.3 0.7 5e-10 39.7 0.7 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Fig1 PF12351.8 EGO20022.1 - 1.9 8.4 6.0 0.31 10.9 1.2 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Ndc1_Nup PF09531.10 EGO20023.1 - 1.8e-107 360.6 4.7 2.1e-107 360.4 4.7 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup AAA PF00004.29 EGO20024.1 - 8.7e-75 249.4 0.0 2e-40 138.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO20024.1 - 8.3e-25 86.3 0.1 1.1e-12 47.6 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGO20024.1 - 1e-12 48.8 0.4 5.7e-05 23.6 0.1 4.4 2 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EGO20024.1 - 3.7e-12 46.3 0.0 0.00043 20.1 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO20024.1 - 3.7e-11 43.2 0.0 1.7e-05 24.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO20024.1 - 1.3e-09 38.5 0.1 5.5e-05 23.5 0.0 4.2 2 2 0 3 3 3 1 AAA domain AAA_2 PF07724.14 EGO20024.1 - 8.8e-09 35.7 0.0 0.00083 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGO20024.1 - 8.7e-08 32.4 0.0 0.00047 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGO20024.1 - 1.4e-07 31.1 0.0 0.0032 16.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 EGO20024.1 - 2.5e-07 30.6 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EGO20024.1 - 1.3e-05 25.2 0.0 0.036 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGO20024.1 - 0.00014 21.9 0.0 0.14 12.1 0.0 2.6 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGO20024.1 - 0.00015 22.1 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 EGO20024.1 - 0.00017 21.2 0.4 4.3 6.9 0.0 4.0 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EGO20024.1 - 0.00026 20.4 0.3 0.25 10.7 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGO20024.1 - 0.00027 21.5 0.0 0.0042 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGO20024.1 - 0.00031 20.1 0.0 0.023 14.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 EGO20024.1 - 0.00061 19.7 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGO20024.1 - 0.001 19.3 0.0 0.086 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGO20024.1 - 0.001 19.0 0.5 0.7 9.8 0.0 3.4 2 2 1 3 3 3 1 Rad17 P-loop domain AAA_7 PF12775.7 EGO20024.1 - 0.0013 18.3 0.0 0.5 9.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EGO20024.1 - 0.0021 18.0 0.0 0.099 12.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 EGO20024.1 - 0.0074 16.2 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGO20024.1 - 0.012 15.4 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EGO20024.1 - 0.012 15.3 0.0 1 9.1 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGO20024.1 - 0.013 15.2 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO20024.1 - 0.015 15.8 0.1 0.28 11.7 0.0 2.7 3 0 0 3 3 2 0 ABC transporter PhoH PF02562.16 EGO20024.1 - 0.023 14.2 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DAP3 PF10236.9 EGO20024.1 - 0.023 13.9 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 EGO20024.1 - 0.031 13.6 0.0 4.5 6.6 0.0 2.4 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.18 EGO20024.1 - 0.047 13.5 0.0 0.74 9.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein NB-ARC PF00931.22 EGO20024.1 - 0.052 12.7 0.0 2.7 7.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.6 EGO20024.1 - 0.063 13.4 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EGO20024.1 - 0.078 12.1 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EGO20024.1 - 0.15 11.8 0.0 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGO20024.1 - 0.16 12.3 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGO20024.1 - 0.17 11.8 0.0 23 4.8 0.0 2.9 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea Tim17 PF02466.19 EGO20025.1 - 2.7e-12 47.0 1.5 2.7e-12 47.0 0.4 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EGO20025.1 - 0.24 11.6 2.3 11 6.2 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5518) SUIM_assoc PF16619.5 EGO20026.1 - 0.0093 16.0 0.0 0.14 12.2 0.0 2.8 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Holin_BhlA PF10960.8 EGO20026.1 - 0.13 12.2 0.3 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 BhlA holin family Myb_DNA-bind_3 PF12776.7 EGO20026.1 - 0.58 11.2 3.6 4 8.5 0.4 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RVP_2 PF08284.11 EGO20027.1 - 4.2e-06 26.6 0.0 4.7e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO20027.1 - 2.3e-05 24.9 0.0 2.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO20027.1 - 0.0008 20.0 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease p47_phox_C PF08944.11 EGO20029.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Nicastrin PF05450.15 EGO20029.1 - 0.12 11.9 0.1 0.14 11.6 0.1 1.0 1 0 0 1 1 1 0 Nicastrin DUF1841 PF08897.11 EGO20031.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) SKN1 PF03935.15 EGO20033.1 - 5.8e-185 615.5 5.4 7.1e-185 615.2 5.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PBP_like_2 PF12849.7 EGO20034.1 - 0.00045 20.0 0.0 0.00085 19.1 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain LysR_substrate PF03466.20 EGO20034.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Redoxin PF08534.10 EGO20035.1 - 7.3e-39 132.8 0.0 8.3e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGO20035.1 - 4.6e-12 45.9 0.0 5.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family SLATT_fungal PF18142.1 EGO20036.1 - 4.5e-42 142.8 0.2 5.6e-42 142.5 0.2 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Phage_holin_3_6 PF07332.11 EGO20036.1 - 0.0024 17.9 0.4 0.0034 17.4 0.4 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Asp4 PF16996.5 EGO20036.1 - 0.022 14.5 0.4 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 KIP1 PF07765.12 EGO20036.1 - 0.041 14.0 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 KIP1-like protein UPF0270 PF06794.12 EGO20036.1 - 0.079 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Npa1 PF11707.8 EGO20036.1 - 0.088 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DHC_N1 PF08385.12 EGO20036.1 - 0.14 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 FAM184 PF15665.5 EGO20036.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.5 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF4231 PF14015.6 EGO20036.1 - 0.19 12.2 0.7 0.33 11.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ferric_reduct PF01794.19 EGO20038.1 - 1.2e-20 73.8 8.0 1.2e-20 73.8 8.0 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO20038.1 - 2.2e-17 63.6 0.0 1.8e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO20038.1 - 2e-14 53.6 0.1 5.9e-13 48.9 0.1 2.4 1 1 0 1 1 1 1 FAD-binding domain Mit_proteolip PF08039.11 EGO20038.1 - 0.077 13.4 0.5 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial proteolipid adh_short_C2 PF13561.6 EGO20039.1 - 8.9e-59 198.9 1.6 1.2e-58 198.5 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO20039.1 - 1.1e-54 184.8 0.3 1.4e-54 184.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO20039.1 - 4.1e-13 49.6 0.2 6.8e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 KR domain VBS PF08913.10 EGO20039.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Vinculin Binding Site adh_short_C2 PF13561.6 EGO20040.1 - 3.6e-59 200.2 1.6 4.7e-59 199.8 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO20040.1 - 2.4e-55 187.0 1.1 2.9e-55 186.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO20040.1 - 1.2e-11 44.9 1.9 1.7e-11 44.3 1.9 1.3 1 0 0 1 1 1 1 KR domain DUF1173 PF06666.11 EGO20040.1 - 0.02 13.9 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) 3HCDH_N PF02737.18 EGO20040.1 - 0.028 14.3 0.2 0.051 13.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF569 PF04601.13 EGO20041.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF569) F-box-like PF12937.7 EGO20042.1 - 0.00034 20.5 2.7 0.00056 19.7 1.7 2.0 2 0 0 2 2 2 1 F-box-like Solute_trans_a PF03619.16 EGO20043.1 - 8e-96 320.6 11.6 9.5e-96 320.4 11.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Lyase_8 PF02278.18 EGO20045.1 - 1.8e-67 227.6 5.3 3.3e-67 226.7 5.3 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 EGO20045.1 - 4.2e-22 78.5 0.1 6.5e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 EGO20045.1 - 9.1e-08 32.5 0.4 2.6e-07 31.0 0.4 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Spt5-NGN PF03439.13 EGO20045.1 - 0.12 12.3 0.2 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section Glyco_hydro_1 PF00232.18 EGO20047.1 - 6.8e-20 70.9 0.0 7.7e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Hemerythrin PF01814.23 EGO20048.1 - 7.7e-13 49.2 1.5 1.1e-12 48.7 1.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short PF00106.25 EGO20050.1 - 3.3e-38 131.1 0.1 5.4e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20050.1 - 8.3e-27 94.3 0.0 1.1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20050.1 - 0.00047 20.1 0.1 0.00068 19.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO20050.1 - 0.00049 20.0 0.1 0.00074 19.5 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO20050.1 - 0.0036 16.8 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DPBB_1 PF03330.18 EGO20052.1 - 4.1e-13 49.4 0.0 6.7e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGO20052.1 - 0.022 14.6 0.0 0.056 13.3 0.0 1.5 1 1 1 2 2 2 0 Barwin family Cerato-platanin PF07249.12 EGO20052.1 - 0.028 14.5 0.0 0.063 13.4 0.0 1.5 1 1 0 1 1 1 0 Cerato-platanin DPBB_1 PF03330.18 EGO20054.1 - 2e-12 47.2 0.5 6.2e-12 45.6 0.5 2.1 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 EGO20054.1 - 0.011 15.8 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 0 Cerato-platanin DPBB_1 PF03330.18 EGO20056.1 - 2.4e-10 40.5 0.7 7.2e-10 39.0 0.7 2.0 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 EGO20056.1 - 0.021 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Cerato-platanin AhpC-TSA PF00578.21 EGO20057.1 - 4.8e-31 107.2 0.0 6.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO20057.1 - 2e-13 50.3 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGO20057.1 - 1.2e-11 44.2 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin TIM PF00121.18 EGO20058.1 - 5.1e-89 297.8 0.1 5.8e-89 297.6 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 EGO20058.1 - 0.0076 15.8 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 CutC family Aldedh PF00171.22 EGO20059.1 - 6.4e-83 278.8 0.0 8.6e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO20059.1 - 0.034 13.2 0.0 0.11 11.5 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF4834 PF16118.5 EGO20060.1 - 0.15 13.0 0.1 1.3 10.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Alpha_kinase PF02816.18 EGO20062.1 - 1.9e-12 47.7 0.0 2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF2689 PF10894.8 EGO20062.1 - 0.053 13.3 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) HTH_Tnp_ISL3 PF13542.6 EGO20065.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 YjcZ PF13990.6 EGO20066.1 - 0.18 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 YjcZ-like protein Pil1 PF13805.6 EGO20068.1 - 6.2e-48 163.6 0.2 9.6e-48 163.0 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Terpene_synth_C PF03936.16 EGO20070.1 - 5.3e-07 29.3 0.0 6.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Methyltransf_2 PF00891.18 EGO20071.1 - 1.1e-20 73.9 0.0 4.4e-19 68.6 0.0 2.1 1 1 1 2 2 2 1 O-methyltransferase domain RPA_C PF08784.11 EGO20071.1 - 7.1e-05 23.4 0.0 0.00047 20.8 0.0 2.2 2 0 0 2 2 2 1 Replication protein A C terminal Methyltransf_16 PF10294.9 EGO20071.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGO20071.1 - 0.01 16.5 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGO20071.1 - 0.019 15.7 0.0 0.049 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGO20071.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain IDO PF01231.18 EGO20073.1 - 0.0035 16.2 0.2 0.08 11.7 0.2 2.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase MFS_1 PF07690.16 EGO20075.1 - 5.1e-19 68.4 35.3 4.7e-10 38.9 14.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGO20075.1 - 8.7e-05 22.0 10.3 8.7e-05 22.0 10.3 2.3 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGO20075.1 - 0.00023 20.1 9.0 0.00034 19.6 9.0 1.2 1 0 0 1 1 1 1 MFS_1 like family ATG22 PF11700.8 EGO20075.1 - 1.6 7.3 13.8 0.027 13.1 6.3 1.7 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like LapA_dom PF06305.11 EGO20075.1 - 3.3 7.6 4.4 13 5.6 0.0 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Beach PF02138.18 EGO20076.1 - 2.2e-80 270.0 0.0 4.9e-80 268.9 0.0 1.6 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGO20076.1 - 7.8e-08 32.3 0.2 3e-07 30.4 0.2 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EGO20076.1 - 2.1e-06 28.0 2.0 2.5e-06 27.7 0.6 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EGO20076.1 - 4e-05 24.3 1.7 0.23 12.4 0.3 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4704 PF15787.5 EGO20076.1 - 0.00062 19.1 0.2 0.0032 16.8 0.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) DUF3527 PF12043.8 EGO20080.1 - 0.0011 18.6 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) Bap31_Bap29_C PF18035.1 EGO20082.1 - 0.81 9.7 5.0 0.3 11.1 1.2 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EGO20082.1 - 1.1 9.1 4.7 0.8 9.5 1.8 2.2 2 0 0 2 2 2 0 Septum formation initiator hNIFK_binding PF12196.8 EGO20082.1 - 4.8 6.8 6.1 0.68 9.5 1.4 2.1 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK p450 PF00067.22 EGO20083.1 - 1.9e-75 254.4 0.0 2.1e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 EGO20083.1 - 0.0009 19.5 0.0 0.0034 17.6 0.0 1.9 1 0 0 1 1 1 1 Serine endopeptidase inhibitors GMC_oxred_N PF00732.19 EGO20084.1 - 1.7e-59 201.6 0.0 2.3e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO20084.1 - 4.2e-29 101.9 0.0 1.4e-24 87.2 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_3 PF13738.6 EGO20084.1 - 4.3e-07 29.5 0.3 0.0053 16.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO20084.1 - 1.3e-05 25.0 0.6 0.0027 17.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO20084.1 - 0.00015 21.1 0.3 0.0056 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO20084.1 - 0.00016 20.9 1.4 0.0048 16.0 0.4 2.7 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 EGO20084.1 - 0.00024 20.3 0.1 0.00036 19.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGO20084.1 - 0.00078 19.6 0.4 0.003 17.8 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO20084.1 - 0.055 12.7 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EGO20084.1 - 0.14 10.9 0.8 0.29 9.8 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein STE3 PF02076.15 EGO20085.1 - 9.2e-92 307.3 14.7 1.2e-91 306.9 14.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor adh_short PF00106.25 EGO20086.1 - 2.8e-20 72.6 0.3 3.1e-15 56.2 0.1 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20086.1 - 3.6e-09 36.5 0.0 6e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20086.1 - 1.9e-07 31.2 0.1 3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO20086.1 - 6.6e-05 22.5 0.1 0.0031 17.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EGO20086.1 - 0.0064 16.9 0.0 0.099 13.1 0.0 2.6 1 1 0 1 1 1 1 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 EGO20086.1 - 0.027 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EGO20086.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 EGO20086.1 - 0.14 12.0 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus RNase_P_p30 PF01876.16 EGO20087.1 - 2.2e-36 125.3 0.0 3.2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 adh_short PF00106.25 EGO20088.1 - 6.2e-48 162.8 0.1 7.7e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20088.1 - 8.9e-34 117.1 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGO20088.1 - 6.9e-05 22.4 0.0 0.0001 21.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGO20088.1 - 9.5e-05 22.4 0.0 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO20088.1 - 0.00082 18.8 0.0 0.0021 17.5 0.0 1.6 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EGO20088.1 - 0.087 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGO20088.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PAE PF03283.13 EGO20088.1 - 0.21 10.7 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Ferric_reduct PF01794.19 EGO20091.1 - 3.6e-20 72.3 8.2 6.5e-20 71.5 8.2 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO20091.1 - 1.2e-19 70.9 0.0 2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO20091.1 - 6.8e-16 58.3 0.0 2.7e-15 56.4 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EGO20091.1 - 0.13 12.9 0.0 2.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Oxidored_FMN PF00724.20 EGO20092.1 - 6.3e-101 338.1 0.0 7.2e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 EGO20093.1 - 1.6e-94 317.0 0.0 1.8e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TAL_FSA PF00923.19 EGO20094.1 - 6.2e-93 311.3 0.0 7.1e-93 311.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CDH-cyt PF16010.5 EGO20095.1 - 2.2e-50 170.9 1.1 2.2e-50 170.9 1.1 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EGO20095.1 - 2e-19 70.1 0.0 3.9e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO20095.1 - 1.8e-18 67.5 0.0 5.7e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO20095.1 - 2.8e-06 26.7 0.1 6.8e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGO20095.1 - 2.1e-05 24.7 0.0 6.9e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGO20095.1 - 9.5e-05 21.9 0.0 0.00021 20.8 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO20095.1 - 0.00012 21.5 0.1 0.00019 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO20095.1 - 0.00013 21.3 0.1 0.0002 20.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO20095.1 - 0.00019 20.3 0.1 0.00032 19.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGO20095.1 - 0.00041 20.0 0.1 0.0053 16.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO20095.1 - 0.001 18.4 0.5 0.007 15.7 0.8 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO20095.1 - 0.0021 17.3 0.1 0.023 14.0 0.2 2.1 2 0 0 2 2 2 1 Thi4 family SH3_4 PF06347.13 EGO20095.1 - 0.083 12.7 0.3 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Lycopene_cycl PF05834.12 EGO20095.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EGO20095.1 - 0.18 10.9 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxal_oxid_N PF07250.11 EGO20096.1 - 1.6e-30 106.1 0.5 2.4e-13 49.8 0.0 5.0 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGO20096.1 - 1.1e-23 83.3 2.0 2.4e-23 82.2 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF456 PF04306.13 EGO20096.1 - 0.035 14.4 3.7 0.096 13.0 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Podoplanin PF05808.11 EGO20096.1 - 0.074 13.1 3.0 0.16 12.0 3.0 1.5 1 0 0 1 1 1 0 Podoplanin Sortilin-Vps10 PF15902.5 EGO20097.1 - 1.2e-11 44.1 12.9 0.0051 15.7 0.0 6.0 5 1 0 6 6 6 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 EGO20097.1 - 3.7e-06 26.1 34.7 0.88 9.8 0.1 9.4 9 0 0 9 9 9 7 BNR/Asp-box repeat BNR_6 PF15899.5 EGO20097.1 - 4.9e-06 26.1 7.3 0.33 11.1 0.0 6.0 5 0 0 5 5 5 2 BNR-Asp box repeat DUF3725 PF12523.8 EGO20098.1 - 0.056 13.7 0.0 0.06 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) FMO-like PF00743.19 EGO20099.1 - 2.1e-15 56.2 0.0 1.1e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO20099.1 - 1.7e-14 53.8 0.0 1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO20099.1 - 3.3e-12 46.2 0.0 3.6e-10 39.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGO20099.1 - 4.9e-09 35.9 0.0 0.0029 16.9 0.1 3.4 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO20099.1 - 3.8e-08 33.4 0.9 1.5e-05 25.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGO20099.1 - 4.6e-07 29.5 0.1 0.015 14.6 0.0 3.2 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGO20099.1 - 1.1e-05 25.2 7.1 0.099 12.2 0.6 3.7 2 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO20099.1 - 2.4e-05 24.4 2.7 0.44 10.5 0.1 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EGO20099.1 - 2.7e-05 24.5 0.0 0.08 13.4 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EGO20099.1 - 0.00088 18.6 0.7 0.0075 15.6 0.2 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGO20099.1 - 0.00092 19.7 3.5 0.0084 16.7 0.5 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO20099.1 - 0.0056 15.9 1.7 0.28 10.4 0.2 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 EGO20099.1 - 0.0073 15.4 4.0 0.043 12.9 0.6 3.0 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 EGO20099.1 - 0.008 16.2 0.1 2.5 8.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EGO20099.1 - 0.0098 14.6 5.5 0.033 12.9 0.2 3.4 4 0 0 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 EGO20099.1 - 0.029 13.7 1.3 0.071 12.4 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGO20099.1 - 0.041 12.9 0.9 2.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein IlvN PF07991.12 EGO20099.1 - 0.042 13.4 0.5 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EGO20099.1 - 0.084 11.9 4.1 16 4.5 0.7 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EGO20099.1 - 0.45 10.4 2.5 18 5.2 0.4 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LRR_4 PF12799.7 EGO20100.1 - 0.14 12.6 0.9 2.9 8.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF5031 PF16434.5 EGO20100.1 - 0.17 11.0 0.0 0.58 9.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5031) F-box-like PF12937.7 EGO20100.1 - 0.22 11.4 1.5 0.71 9.8 1.5 1.9 1 0 0 1 1 1 0 F-box-like ADH_zinc_N PF00107.26 EGO20101.1 - 8.5e-26 90.5 0.2 1.3e-25 89.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO20101.1 - 1.7e-19 71.2 0.0 3.4e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO20101.1 - 2.2e-12 46.8 0.1 5.6e-12 45.5 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGO20101.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DAGK_cat PF00781.24 EGO20101.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain KDZ PF18758.1 EGO20103.1 - 1.3e-07 31.4 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Ish1 PF10281.9 EGO20104.1 - 0.005 17.1 0.5 0.016 15.5 0.3 2.0 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Med23 PF11573.8 EGO20106.1 - 0.061 11.0 0.3 0.082 10.6 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 DUF5054 PF16477.5 EGO20107.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) Pkinase PF00069.25 EGO20108.1 - 4.3e-08 32.8 0.0 8.1e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO20108.1 - 1.2e-07 31.3 0.0 6.9e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGO20108.1 - 0.00069 19.3 0.0 0.0024 17.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGO20108.1 - 0.00092 19.2 0.0 0.005 16.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO20108.1 - 0.0017 17.8 0.0 0.0043 16.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_1 PF03184.19 EGO20109.1 - 7.2e-14 51.8 0.0 4.6e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease SAP PF02037.27 EGO20109.1 - 0.13 12.0 0.9 0.31 10.8 0.0 2.1 3 0 0 3 3 3 0 SAP domain PSI PF01437.25 EGO20110.1 - 0.045 14.3 1.4 0.045 14.3 1.4 2.0 2 0 0 2 2 2 0 Plexin repeat Zn_clus PF00172.18 EGO20110.1 - 5.3 7.2 8.6 45 4.3 8.7 2.1 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.19 EGO20111.1 - 3.7e-13 48.9 0.0 3.2e-06 26.1 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain GPHR_N PF12537.8 EGO20112.1 - 7.2e-10 38.8 0.2 1.1e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF1418 PF07214.12 EGO20112.1 - 0.25 11.2 4.3 2.5 8.0 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) ABC2_membrane_3 PF12698.7 EGO20112.1 - 7.6 5.5 11.0 8.9 5.3 11.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein OrfB_Zn_ribbon PF07282.11 EGO20119.1 - 0.0045 16.9 0.1 0.0065 16.4 0.1 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain 2OG-FeII_Oxy_2 PF13532.6 EGO20120.1 - 1.5e-11 44.9 0.0 6e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.23 EGO20121.1 - 7.1e-09 35.5 0.3 1.3e-08 34.6 0.3 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO20121.1 - 0.0051 16.6 0.1 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase KI67R PF08065.12 EGO20121.1 - 0.084 13.4 0.6 0.14 12.7 0.6 1.5 1 0 0 1 1 1 0 KI67R (NUC007) repeat PEMT PF04191.13 EGO20122.1 - 3.9e-52 175.1 9.6 4.2e-28 97.8 1.6 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 EGO20122.1 - 0.067 13.8 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 SKICH domain Mating_N PF12731.7 EGO20122.1 - 0.08 13.0 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 PID PF00640.23 EGO20122.1 - 0.15 12.1 0.4 25 4.9 0.1 2.6 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) NESP55 PF06390.12 EGO20122.1 - 0.29 10.7 4.3 0.47 10.0 4.3 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Aminotran_3 PF00202.21 EGO20123.1 - 2e-116 389.0 0.0 2.4e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGO20123.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DHHC PF01529.20 EGO20124.1 - 5.8e-33 113.8 9.2 5.8e-33 113.8 9.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Orf78 PF06024.12 EGO20124.1 - 0.16 12.3 2.7 2.2 8.6 0.4 2.4 2 0 0 2 2 2 0 Orf78 (ac78) DUF3784 PF12650.7 EGO20124.1 - 1.7 8.9 0.0 1.7 8.9 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) OAD_gamma PF04277.13 EGO20124.1 - 2.8 8.6 4.2 16 6.2 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RNase_P_Rpp14 PF01900.19 EGO20125.1 - 0.012 15.9 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 Rpp14/Pop5 family Cullin_binding PF03556.15 EGO20126.1 - 3e-34 118.0 0.2 4.8e-34 117.4 0.2 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EGO20126.1 - 2.6e-07 30.3 0.2 7.2e-07 28.9 0.2 1.8 1 1 0 1 1 1 1 UBA-like domain MPP6 PF10175.9 EGO20130.1 - 2.9e-06 27.8 0.0 7.8e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 M-phase phosphoprotein 6 p450 PF00067.22 EGO20133.1 - 3.3e-62 210.7 0.0 4.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NDUF_C2 PF06374.11 EGO20133.1 - 0.042 14.0 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) UCR_6-4kD PF08997.10 EGO20133.1 - 0.16 11.9 0.6 0.45 10.5 0.6 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein NACHT PF05729.12 EGO20134.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EGO20134.1 - 0.043 14.2 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADH_zinc_N PF00107.26 EGO20136.1 - 5.2e-28 97.6 0.4 8.2e-28 97.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO20136.1 - 2.7e-21 77.0 0.7 4.1e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO20136.1 - 5.2e-12 45.6 0.1 1.3e-11 44.3 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EGO20136.1 - 0.019 14.3 0.3 0.025 13.8 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAGK_cat PF00781.24 EGO20136.1 - 0.092 12.4 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TrkA_N PF02254.18 EGO20136.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 EGO20137.1 - 2e-26 93.0 0.0 5.2e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO20137.1 - 3.9e-08 32.9 0.0 1.9e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Fes1 PF08609.10 EGO20143.1 - 4.5e-26 91.6 1.8 1.9e-25 89.6 1.3 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EGO20143.1 - 0.0001 22.6 0.4 0.0094 16.3 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EGO20143.1 - 0.0061 16.7 0.2 17 6.0 0.0 4.0 4 1 0 4 4 4 2 HEAT repeat SIL1 PF16782.5 EGO20143.1 - 0.0086 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_EZ PF13513.6 EGO20143.1 - 0.014 15.8 1.4 11 6.7 0.1 4.2 3 1 0 3 3 3 0 HEAT-like repeat DuoxA PF10204.9 EGO20145.1 - 0.13 11.3 2.3 0.65 9.0 0.5 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor Glyco_hydro_115 PF15979.5 EGO20146.1 - 1.9e-136 455.0 3.6 2.9e-136 454.4 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EGO20146.1 - 4.8e-53 179.5 0.0 8.5e-53 178.7 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Chromo PF00385.24 EGO20147.1 - 2.6e-06 27.3 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EGO20148.1 - 5.1e-09 35.8 3.8 7.6e-09 35.3 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO20148.1 - 0.067 12.9 1.4 0.094 12.5 1.4 1.2 1 0 0 1 1 1 0 Zinc knuckle DUF2235 PF09994.9 EGO20151.1 - 2.2e-69 234.0 0.0 2.8e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DEC-1_N PF04625.13 EGO20151.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5488 PF17590.2 EGO20153.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Sec_GG PF07549.14 EGO20154.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 SecD/SecF GG Motif LHC PF00556.20 EGO20154.1 - 1.1 9.5 5.4 0.38 11.0 2.8 1.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Sec_GG PF07549.14 EGO20155.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif ERG4_ERG24 PF01222.17 EGO20157.1 - 1.2e-134 449.4 7.2 2.1e-134 448.5 7.2 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGO20157.1 - 6e-07 29.2 0.3 6e-07 29.2 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGO20157.1 - 4.7e-06 26.9 0.0 4.7e-06 26.9 0.0 3.0 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 EGO20157.1 - 0.00035 20.9 0.4 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Glyco_hydro_71 PF03659.14 EGO20158.1 - 4.5e-125 417.4 4.0 5.1e-125 417.2 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Histone PF00125.24 EGO20162.1 - 1e-18 68.0 0.0 1.1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGO20162.1 - 9.3e-10 38.1 0.1 1.9e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGO20162.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_31 PF13847.6 EGO20163.1 - 1.5e-30 106.0 0.0 1.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO20163.1 - 2.7e-24 85.7 0.0 4.7e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO20163.1 - 7.4e-24 84.2 0.0 1.3e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO20163.1 - 7.8e-16 58.4 0.0 9.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO20163.1 - 8.7e-16 58.0 0.0 1.2e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGO20163.1 - 1.5e-15 57.7 0.0 2.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO20163.1 - 1.2e-10 41.6 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EGO20163.1 - 2.5e-07 30.4 0.0 6e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 EGO20163.1 - 7e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGO20163.1 - 7.1e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EGO20163.1 - 7.3e-05 21.8 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltr_RsmB-F PF01189.17 EGO20163.1 - 0.00021 21.0 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NodS PF05401.11 EGO20163.1 - 0.00078 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EGO20163.1 - 0.00097 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EGO20163.1 - 0.0014 18.0 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 EGO20163.1 - 0.0029 16.7 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 EGO20163.1 - 0.0037 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Phos_pyr_kin PF08543.12 EGO20163.1 - 0.0041 16.5 0.1 0.006 16.0 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Methyltransf_29 PF03141.16 EGO20163.1 - 0.0051 15.4 0.0 0.008 14.8 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 EGO20163.1 - 0.0069 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EGO20163.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.15 EGO20163.1 - 0.099 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.10 EGO20163.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase adh_short PF00106.25 EGO20164.1 - 2.6e-35 121.7 0.0 3.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20164.1 - 3.9e-24 85.5 0.0 6.1e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20164.1 - 1.3e-09 38.3 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO20164.1 - 0.00016 21.6 0.2 0.00025 21.0 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding SUR7 PF06687.12 EGO20165.1 - 5.7e-08 32.7 16.0 5e-07 29.6 15.8 2.2 1 1 0 1 1 1 1 SUR7/PalI family DUF4870 PF09685.10 EGO20165.1 - 0.74 10.0 8.2 0.15 12.2 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) Plavaka PF18759.1 EGO20166.1 - 8.4e-73 245.4 6.2 7.7e-62 209.4 0.2 2.3 1 1 1 2 2 2 2 Plavaka transposase SUR7 PF06687.12 EGO20167.1 - 1.7e-13 50.7 19.6 3e-13 49.9 19.2 1.6 1 1 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 EGO20167.1 - 0.032 14.0 2.7 0.048 13.5 2.7 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2768 PF10966.8 EGO20167.1 - 0.053 14.0 0.2 0.053 14.0 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2768) Sde2_N_Ubi PF13019.6 EGO20167.1 - 0.13 12.1 0.1 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Cad PF03596.13 EGO20167.1 - 1.4 8.8 6.6 0.15 11.9 1.9 1.7 2 0 0 2 2 2 0 Cadmium resistance transporter DUF4293 PF14126.6 EGO20167.1 - 1.9 8.7 10.4 9.9 6.4 10.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) CPP1-like PF11833.8 EGO20167.1 - 2.4 7.8 6.5 3.8 7.1 6.5 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DuoxA PF10204.9 EGO20167.1 - 4.1 6.3 12.8 0.082 11.9 5.3 1.8 2 0 0 2 2 2 0 Dual oxidase maturation factor Tmemb_18A PF09771.9 EGO20167.1 - 6.7 7.1 6.6 1 9.7 1.6 2.1 2 1 1 3 3 3 0 Transmembrane protein 188 IATP PF04568.12 EGO20168.1 - 3e-08 34.0 1.5 3.1e-08 33.9 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP RNA_pol PF00940.19 EGO20169.1 - 2.2e-185 616.4 0.0 3e-185 615.9 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGO20169.1 - 6.1e-97 325.0 0.0 1.5e-96 323.8 0.0 1.7 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Adaptin_N PF01602.20 EGO20171.1 - 1.3e-140 469.5 9.6 1.6e-140 469.2 9.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO20171.1 - 2e-59 200.2 5.9 4.6e-59 199.1 1.2 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO20171.1 - 2.6e-16 59.8 4.0 2e-06 28.1 0.0 5.8 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 EGO20171.1 - 8.3e-09 35.0 7.5 0.00058 19.9 0.1 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EGO20171.1 - 3.4e-06 27.4 0.5 1.8 9.1 0.0 6.0 6 0 0 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 EGO20171.1 - 0.00054 20.1 0.3 0.24 11.6 0.0 3.5 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGO20171.1 - 0.0019 17.8 0.5 0.55 9.8 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal Sec7_N PF12783.7 EGO20171.1 - 0.0053 16.7 1.7 0.031 14.2 0.4 2.7 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 EGO20171.1 - 0.0057 16.7 5.1 17 5.6 0.0 5.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat ATP-synt_A PF00119.20 EGO20171.1 - 0.17 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase A chain DUF2544 PF11245.8 EGO20172.1 - 0.032 13.7 0.1 0.038 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) Glyco_hydro_30 PF02055.16 EGO20173.1 - 2.4e-21 76.1 1.1 3.3e-21 75.6 1.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EGO20173.1 - 3.8e-13 49.3 0.2 5.8e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EGO20173.1 - 0.007 16.0 0.0 0.98 8.9 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 EGO20173.1 - 0.023 14.2 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Tropomyosin PF00261.20 EGO20174.1 - 0.07 12.5 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin p450 PF00067.22 EGO20176.1 - 4e-70 236.8 0.0 4.8e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO20177.1 - 2.8e-66 224.2 0.0 3.4e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1289 PF06945.13 EGO20178.1 - 0.0079 16.0 0.6 0.017 14.9 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) RSN1_TM PF13967.6 EGO20179.1 - 0.061 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport CAP_N PF01213.19 EGO20179.1 - 0.43 10.0 2.6 0.66 9.4 2.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Epimerase PF01370.21 EGO20180.1 - 2.2e-15 56.8 0.0 2.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO20180.1 - 1.4e-12 47.6 0.0 2.7e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGO20180.1 - 3.4e-07 29.7 0.0 0.00078 18.7 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EGO20180.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGO20180.1 - 6.4e-06 25.4 0.0 8.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EGO20180.1 - 0.017 14.5 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 EGO20180.1 - 0.044 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO20180.1 - 0.047 12.8 0.0 1.5 7.9 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 EGO20180.1 - 0.065 13.1 0.1 0.3 11.0 0.1 1.9 1 1 0 1 1 1 0 KR domain SPX PF03105.19 EGO20181.1 - 0.026 14.5 2.6 0.041 13.8 2.6 1.2 1 0 0 1 1 1 0 SPX domain Kelch_4 PF13418.6 EGO20187.1 - 1.4e-37 127.4 12.1 7.7e-07 29.0 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO20187.1 - 1.9e-34 117.1 11.2 3.3e-08 33.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGO20187.1 - 1e-33 114.7 15.5 6.6e-08 32.0 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGO20187.1 - 1.2e-30 105.1 16.4 6.3e-06 26.4 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGO20187.1 - 1.4e-30 104.6 16.4 5.6e-08 32.8 0.0 6.6 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGO20187.1 - 1e-22 79.1 12.9 3e-05 23.8 0.2 6.5 6 0 0 6 6 6 6 Kelch motif DUF3984 PF13136.6 EGO20187.1 - 0.12 11.8 5.6 0.17 11.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SMP PF04927.12 EGO20188.1 - 0.0068 16.9 13.8 0.012 16.0 0.9 3.0 3 1 0 3 3 3 2 Seed maturation protein Es2 PF09751.9 EGO20189.1 - 5.7e-72 243.8 12.7 2.9e-69 234.9 12.7 2.2 1 1 0 1 1 1 1 Nuclear protein Es2 SUI1 PF01253.22 EGO20190.1 - 5.3e-17 62.1 0.0 1.5e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EGO20190.1 - 5.2e-15 55.9 0.0 5.3e-14 52.7 0.0 2.6 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 EGO20190.1 - 0.00014 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 EGO20190.1 - 0.041 13.8 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 SWIB/MDM2 domain RrnaAD PF00398.20 EGO20191.1 - 1.5e-61 207.8 0.0 1.9e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGO20191.1 - 4.4e-07 30.5 0.0 8.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO20191.1 - 2.9e-05 24.6 0.0 6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO20191.1 - 0.00039 21.1 0.0 0.00079 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO20191.1 - 0.00046 20.1 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO20191.1 - 0.00058 19.7 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGO20191.1 - 0.00083 18.9 0.0 0.0019 17.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 EGO20191.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EGO20191.1 - 0.0039 16.5 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 EGO20191.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 EGO20191.1 - 0.034 13.8 0.0 0.092 12.4 0.0 1.7 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EGO20191.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.11 EGO20191.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EGO20191.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family tRNA-synt_1 PF00133.22 EGO20193.1 - 1.6e-35 122.5 0.0 3.1e-26 91.8 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGO20193.1 - 5.4e-16 58.9 0.1 8.8e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGO20193.1 - 1.2e-14 53.9 0.0 1.4e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGO20193.1 - 7.6e-08 32.0 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Oxysterol_BP PF01237.18 EGO20195.1 - 5.3e-60 203.2 1.5 4.3e-51 173.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein PseudoU_synth_1 PF01416.20 EGO20196.1 - 4.6e-26 91.4 0.0 4.2e-24 85.1 0.0 3.3 2 2 0 2 2 2 1 tRNA pseudouridine synthase MGC-24 PF05283.11 EGO20196.1 - 0.48 10.9 2.8 21 5.6 1.4 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GCN5L1 PF06320.13 EGO20197.1 - 0.015 15.5 7.0 0.016 15.4 7.0 1.0 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF2730 PF10805.8 EGO20197.1 - 0.021 14.9 1.9 0.064 13.4 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF16 PF01519.16 EGO20197.1 - 0.027 15.0 8.1 0.032 14.7 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF16 Tox-GHH PF15636.6 EGO20197.1 - 0.04 13.9 2.8 0.047 13.7 2.8 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin WXG100 PF06013.12 EGO20197.1 - 0.054 13.7 2.6 2.8 8.2 0.4 2.4 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF4790 PF16037.5 EGO20197.1 - 0.059 13.8 2.0 0.07 13.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) DUF1664 PF07889.12 EGO20197.1 - 0.062 13.3 4.2 0.091 12.8 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Surfac_D-trimer PF09006.11 EGO20197.1 - 0.081 12.8 0.5 0.73 9.8 0.1 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Spc7 PF08317.11 EGO20197.1 - 0.11 11.4 11.0 0.12 11.2 11.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Phlebovirus_NSM PF07246.11 EGO20197.1 - 0.12 11.7 5.7 0.18 11.2 5.3 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GldM_N PF12081.8 EGO20197.1 - 0.16 12.0 7.0 0.17 12.0 7.0 1.0 1 0 0 1 1 1 0 GldM N-terminal domain DUF2207 PF09972.9 EGO20197.1 - 0.19 10.5 1.7 0.18 10.5 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HIP1_clath_bdg PF16515.5 EGO20197.1 - 0.2 12.3 9.4 0.35 11.5 9.2 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4618 PF15397.6 EGO20197.1 - 0.29 10.5 10.0 1.3 8.4 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 EGO20197.1 - 0.3 10.5 12.1 0.82 9.1 3.0 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 TMPIT PF07851.13 EGO20197.1 - 0.33 10.1 6.3 0.37 10.0 6.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein Muted PF14942.6 EGO20197.1 - 0.39 11.1 11.8 0.92 9.8 11.8 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein bZIP_1 PF00170.21 EGO20197.1 - 0.67 10.1 9.1 2.6 8.2 0.9 2.8 1 1 1 2 2 2 0 bZIP transcription factor OmpH PF03938.14 EGO20197.1 - 1 9.7 13.1 1.1 9.5 13.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pepsin-I3 PF06394.13 EGO20197.1 - 1.4 9.1 5.6 3.8 7.8 1.1 2.1 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain Phage_Gp23 PF10669.9 EGO20197.1 - 1.6 9.0 9.4 1.8 8.9 9.0 1.3 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Mt_ATP-synt_D PF05873.12 EGO20197.1 - 2 8.2 9.6 1.3 8.9 6.4 1.8 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) FapA PF03961.13 EGO20197.1 - 2.6 6.6 10.7 3 6.4 10.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 EGO20197.1 - 3.6 7.9 9.7 4.2 7.6 9.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein HMG_box PF00505.19 EGO20198.1 - 2.4e-23 82.3 1.0 2.4e-23 82.3 1.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO20198.1 - 1.6e-16 60.7 1.1 1.6e-16 60.7 1.1 1.9 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 EGO20198.1 - 0.00087 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 EGO20198.1 - 0.014 16.0 0.4 0.021 15.4 0.3 1.4 1 1 0 1 1 1 0 YABBY protein Flavi_capsid PF01003.19 EGO20198.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C Protamine_like PF06382.11 EGO20198.1 - 0.15 12.2 2.9 0.19 11.9 2.9 1.1 1 0 0 1 1 1 0 Protamine and protamine like RR_TM4-6 PF06459.12 EGO20198.1 - 3.2 7.5 6.6 5.4 6.7 6.6 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC2 PF04084.14 EGO20199.1 - 7.5e-59 199.3 0.0 8.9e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC2 PF04084.14 EGO20200.1 - 1.1e-15 57.4 0.0 1.2e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Plavaka PF18759.1 EGO20205.1 - 1.5e-108 362.9 0.7 1.8e-107 359.4 0.7 2.0 1 1 0 1 1 1 1 Plavaka transposase LLC1 PF14945.6 EGO20206.1 - 0.049 14.2 0.7 1.4 9.5 0.1 2.9 3 0 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Phage_integrase PF00589.22 EGO20207.1 - 0.0047 16.7 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 Phage integrase family Amino_oxidase PF01593.24 EGO20208.1 - 5.2e-50 171.0 0.0 6.7e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO20208.1 - 0.00017 21.8 0.0 0.00057 20.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain EF1G PF00647.19 EGO20209.1 - 4.3e-43 145.7 0.0 8.3e-43 144.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGO20209.1 - 1.6e-11 44.4 0.0 6e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO20209.1 - 1.8e-09 37.7 0.0 5.3e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO20209.1 - 1.3e-06 28.7 0.0 3.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO20209.1 - 1e-05 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO20209.1 - 0.00059 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO20209.1 - 0.0027 17.7 0.0 0.0077 16.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.19 EGO20209.1 - 0.07 13.7 7.3 0.14 12.7 7.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein OAD_gamma PF04277.13 EGO20209.1 - 3.9 8.2 6.1 7.9 7.2 6.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DNA_pol_E_B PF04042.16 EGO20211.1 - 0.14 11.5 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 EGO20213.1 - 7.8e-05 22.2 0.1 0.0009 18.7 0.1 2.2 1 1 0 2 2 2 2 Protein kinase domain Nif11 PF07862.11 EGO20214.1 - 0.086 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Nif11 domain CHAT PF12770.7 EGO20215.1 - 2.4e-34 119.1 0.1 5.8e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 EGO20215.1 - 5.2e-19 67.5 13.9 0.033 14.1 0.0 12.3 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGO20215.1 - 3.1e-15 55.6 0.0 0.094 12.4 0.0 10.5 11 1 0 11 11 11 3 TPR repeat TPR_1 PF00515.28 EGO20215.1 - 3e-13 49.0 13.4 0.059 13.2 0.0 11.6 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO20215.1 - 3.5e-13 48.6 0.0 1.7 9.1 0.0 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO20215.1 - 3.7e-12 45.4 10.2 0.19 11.9 0.0 11.1 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO20215.1 - 4.3e-12 46.2 10.2 0.56 10.5 0.0 12.0 8 2 5 13 13 11 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO20215.1 - 1.1e-11 44.6 17.0 1.4 9.9 0.0 11.5 11 2 2 13 13 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO20215.1 - 2.1e-05 25.1 13.5 8.7 7.1 0.0 8.2 5 3 4 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO20215.1 - 3.9e-05 23.4 3.9 1.9 8.7 0.0 8.3 10 0 0 10 10 8 1 Tetratricopeptide repeat DUF2379 PF09543.10 EGO20215.1 - 7.6e-05 22.9 0.5 0.82 9.9 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2379) TPR_17 PF13431.6 EGO20215.1 - 0.00016 21.8 4.7 0.68 10.4 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO20215.1 - 0.00038 20.0 3.2 0.01 15.3 0.3 3.7 2 1 1 3 3 3 1 MalT-like TPR region Imm53 PF15580.6 EGO20215.1 - 0.00047 19.8 0.3 13 5.5 0.0 6.3 7 1 1 8 8 7 0 Immunity protein 53 SMBP PF16785.5 EGO20215.1 - 0.0037 17.4 0.2 0.37 11.0 0.0 4.2 5 1 0 5 5 4 1 Small metal-binding protein MIT PF04212.18 EGO20215.1 - 0.004 17.2 0.2 23 5.1 0.0 5.7 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain DUF4855 PF16147.5 EGO20215.1 - 0.12 11.4 0.1 4.5 6.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4855) NAD_binding_10 PF13460.6 EGO20216.1 - 6.8e-28 97.8 0.0 8.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 EGO20216.1 - 0.00022 21.3 0.3 0.24 11.5 0.0 2.4 2 1 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EGO20216.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PhoLip_ATPase_C PF16212.5 EGO20219.1 - 2.3e-52 178.3 24.7 2.3e-52 178.3 24.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO20219.1 - 5.4e-16 58.0 5.4 1.4e-15 56.7 5.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGO20219.1 - 2.1e-15 57.6 0.3 6.7e-10 39.6 0.2 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO20219.1 - 6e-13 48.7 0.0 6e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGO20219.1 - 7.7e-08 32.3 0.0 1.1e-06 28.6 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO20219.1 - 0.00017 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M16 PF00675.20 EGO20220.1 - 1.5e-20 73.7 0.0 2.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO20220.1 - 0.00042 20.4 0.0 0.0017 18.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase M16 inactive domain Methyltransf_25 PF13649.6 EGO20221.1 - 1.3e-12 48.2 0.0 3.6e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO20221.1 - 8.9e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO20221.1 - 1.2e-11 44.7 0.0 4.4e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO20221.1 - 7.7e-11 42.5 0.0 1.4e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO20221.1 - 1.1e-06 29.3 0.1 7.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO20221.1 - 1.2e-06 28.0 0.0 4.4e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EGO20221.1 - 0.00045 20.4 0.0 0.00078 19.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGO20221.1 - 0.00066 19.2 0.0 0.0055 16.2 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 EGO20221.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EGO20221.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain BRCT PF00533.26 EGO20223.1 - 0.00062 20.1 0.0 0.00084 19.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGO20223.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 EGO20223.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DNA_pol_B_palm PF14792.6 EGO20224.1 - 1.5e-27 96.1 0.0 3.7e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 EGO20224.1 - 6.5e-21 73.9 0.3 1.8e-19 69.3 0.1 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 EGO20224.1 - 2e-20 72.7 0.0 4.8e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 EGO20224.1 - 4.2e-16 59.1 0.3 1.9e-15 56.9 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EGO20224.1 - 0.00016 22.2 0.7 0.74 10.5 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix domain NAD_binding_4 PF07993.12 EGO20225.1 - 5.8e-33 114.1 0.0 8.4e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO20225.1 - 1.7e-30 106.0 0.0 2.7e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EGO20225.1 - 2.2e-09 37.2 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO20225.1 - 7.7e-05 23.0 0.0 0.00024 21.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 EGO20225.1 - 0.0093 15.9 0.0 0.058 13.3 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding GAPES4 PF17157.4 EGO20225.1 - 0.16 12.4 0.1 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain T3SS_ATPase_C PF18269.1 EGO20230.1 - 0.0094 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain Acyl-CoA_dh_C PF12806.7 EGO20232.1 - 0.009 16.2 0.2 0.013 15.7 0.2 1.2 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like KMP11 PF03037.16 EGO20234.1 - 0.067 14.0 0.4 0.12 13.1 0.4 1.4 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 WHIM1 PF15612.6 EGO20234.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 N_BRCA1_IG PF16158.5 EGO20236.1 - 1.6e-29 102.6 0.1 4.2e-29 101.3 0.1 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EGO20236.1 - 3.9e-17 61.8 35.4 1.2e-09 37.9 2.9 4.5 4 0 0 4 4 4 3 Zinc finger, ZZ type C1_2 PF03107.16 EGO20236.1 - 3.1e-06 27.4 30.0 0.0007 19.9 5.8 4.5 4 0 0 4 4 4 3 C1 domain TolA_bind_tri PF16331.5 EGO20237.1 - 0.019 15.0 3.7 0.038 14.1 0.1 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation GIT_CC PF16559.5 EGO20237.1 - 0.022 14.6 1.0 0.14 12.0 0.2 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0227 PF05728.12 EGO20237.1 - 0.064 13.2 0.2 0.25 11.3 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) SKA2 PF16740.5 EGO20237.1 - 0.11 12.3 1.9 0.35 10.7 0.2 2.3 1 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF241 PF03087.14 EGO20238.1 - 0.0011 18.8 0.9 0.068 13.0 0.1 2.3 2 0 0 2 2 2 2 Arabidopsis protein of unknown function SEA PF01390.20 EGO20238.1 - 0.018 15.1 0.2 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 SEA domain CdvA PF18822.1 EGO20238.1 - 0.19 11.6 1.4 0.78 9.6 0.6 2.5 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 EGO20238.1 - 0.23 11.5 4.0 0.12 12.5 1.3 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.9 EGO20240.1 - 0.00032 20.5 4.0 0.0024 17.6 0.2 2.2 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TolA_bind_tri PF16331.5 EGO20240.1 - 0.00051 20.1 1.0 0.0043 17.1 0.1 2.5 1 1 1 2 2 2 1 TolA binding protein trimerisation FAM76 PF16046.5 EGO20240.1 - 0.0019 17.6 3.3 0.0028 17.0 3.3 1.2 1 0 0 1 1 1 1 FAM76 protein Bacillus_HBL PF05791.11 EGO20240.1 - 0.0066 16.3 1.9 0.086 12.7 1.8 2.3 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Cnn_1N PF07989.11 EGO20240.1 - 0.014 15.5 4.9 0.073 13.2 4.9 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 EGO20240.1 - 0.017 15.3 6.9 0.02 15.0 5.6 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAP1_N PF04849.13 EGO20240.1 - 0.029 13.6 6.0 0.021 14.0 3.0 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Mod_r PF07200.13 EGO20240.1 - 0.031 14.4 1.8 0.031 14.4 1.8 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.12 EGO20240.1 - 0.054 13.5 2.0 0.33 11.0 1.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GPW_gp25 PF04965.14 EGO20240.1 - 0.07 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme BST2 PF16716.5 EGO20240.1 - 0.086 13.4 3.3 0.5 11.0 1.8 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 OmpH PF03938.14 EGO20240.1 - 0.095 13.0 5.3 0.08 13.3 1.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 EGO20240.1 - 0.18 11.6 6.7 3.1 7.6 1.9 3.1 3 0 0 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.22 EGO20240.1 - 0.36 11.1 8.2 1.9 8.7 6.3 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EGO20240.1 - 0.48 10.4 4.1 8.2 6.5 1.6 2.9 1 1 1 2 2 2 0 Laminin Domain II Cep57_MT_bd PF06657.13 EGO20240.1 - 1.5 9.3 5.1 4.5 7.8 0.2 3.2 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DHR10 PF18595.1 EGO20240.1 - 5.6 7.1 9.3 0.46 10.5 1.5 2.6 3 1 1 4 4 2 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 EGO20241.1 - 0.00066 19.7 0.0 0.034 14.2 0.0 2.7 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 EGO20241.1 - 0.02 15.5 0.9 1.1 9.9 0.2 3.7 4 0 0 4 4 4 0 SlyX Bacillus_HBL PF05791.11 EGO20241.1 - 0.024 14.4 5.4 0.27 11.0 2.1 3.2 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 EGO20241.1 - 0.058 13.7 3.3 1.5 9.1 0.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DivIC PF04977.15 EGO20241.1 - 0.071 12.9 5.0 5 7.0 2.4 2.9 2 0 0 2 2 2 0 Septum formation initiator Exonuc_VII_L PF02601.15 EGO20241.1 - 0.1 12.2 0.9 0.19 11.2 0.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_lysis PF03245.13 EGO20241.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.9 3 1 0 3 3 3 0 Bacteriophage Rz lysis protein Ax_dynein_light PF10211.9 EGO20241.1 - 0.21 11.5 5.9 0.36 10.7 0.7 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain OmpH PF03938.14 EGO20241.1 - 0.54 10.6 6.2 0.15 12.4 1.3 2.4 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 EGO20241.1 - 0.67 10.7 3.2 4.7 8.0 0.2 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus UPF0449 PF15136.6 EGO20241.1 - 1.2 9.6 4.6 5.2 7.6 2.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Syntaxin_2 PF14523.6 EGO20241.1 - 1.8 9.0 7.1 2 8.8 1.1 3.0 2 1 1 3 3 3 0 Syntaxin-like protein Spc7 PF08317.11 EGO20241.1 - 3.8 6.3 8.8 0.58 9.0 1.0 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein DDRGK PF09756.9 EGO20241.1 - 5.7 6.5 8.9 0.12 12.0 1.4 1.9 2 0 0 2 2 2 0 DDRGK domain DUF4618 PF15397.6 EGO20241.1 - 6.2 6.2 10.2 0.49 9.8 2.7 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4618) Prefoldin PF02996.17 EGO20241.1 - 9.2 6.2 9.1 0.86 9.5 1.1 3.1 3 0 0 3 3 3 0 Prefoldin subunit Retrotrans_gag PF03732.17 EGO20242.1 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20242.1 - 0.00048 20.1 3.6 0.0012 18.8 3.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO20242.1 - 1 9.2 5.1 2 8.3 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 EGO20244.1 - 1.6e-08 34.3 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Acyl-ACP_TE PF01643.17 EGO20245.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase DMSP_lyase PF16867.5 EGO20247.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase HET PF06985.11 EGO20248.1 - 3.9e-10 40.2 5.0 8e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Thioredoxin_16 PF18569.1 EGO20249.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain CAF1A PF12253.8 EGO20249.1 - 0.36 11.0 9.1 0.19 11.9 1.5 2.7 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A PRP8_domainIV PF12134.8 EGO20250.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 PRP8 domain IV core adh_short PF00106.25 EGO20251.1 - 9.4e-34 116.6 0.0 1.2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20251.1 - 2.2e-25 89.6 0.0 2.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20251.1 - 6.4e-07 29.5 0.0 1.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO20251.1 - 0.005 16.7 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO20251.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4147 PF13660.6 EGO20252.1 - 0.043 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Dam PF05869.11 EGO20253.1 - 0.071 12.7 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) GATA PF00320.27 EGO20256.1 - 1.9e-25 88.1 19.5 3.5e-15 55.3 3.3 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 EGO20256.1 - 1.3e-11 44.1 0.7 2.5e-11 43.2 0.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Auto_anti-p27 PF06677.12 EGO20256.1 - 0.059 13.5 6.0 0.65 10.2 0.9 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 EGO20256.1 - 0.14 12.1 6.1 4.1 7.3 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EGO20256.1 - 0.39 10.3 7.2 0.43 10.1 0.8 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EGO20256.1 - 0.61 10.2 10.9 1.8 8.8 0.2 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 EGO20256.1 - 0.69 10.2 2.6 0.9 9.9 0.8 2.1 2 0 0 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 EGO20256.1 - 1.3 8.5 6.0 3.3 7.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EGO20256.1 - 2.2 8.3 7.0 1.8 8.5 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 EGO20256.1 - 2.5 8.2 10.0 27 4.9 0.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EGO20256.1 - 3.1 7.8 9.3 2 8.4 2.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.6 EGO20256.1 - 3.5 8.2 8.5 6.2 7.4 1.1 2.4 1 1 2 3 3 3 0 Cytochrome c3 zf-RRN7 PF11781.8 EGO20256.1 - 5.1 6.9 8.9 0.18 11.5 0.9 2.7 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Elf1 PF05129.13 EGO20256.1 - 6.8 6.8 6.8 3.8 7.6 0.2 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like AMP-binding PF00501.28 EGO20257.1 - 3e-90 302.9 0.0 4.2e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO20257.1 - 0.0029 18.5 0.1 0.0091 17.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.6 EGO20258.1 - 4.4e-13 50.0 0.2 7.5e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO20258.1 - 8.3e-07 29.2 0.0 9.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.28 EGO20260.1 - 3.6e-05 22.6 0.0 4.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGO20261.1 - 1e-29 103.5 0.0 1.5e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGO20261.1 - 7.7e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO20261.1 - 0.00019 21.0 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO20261.1 - 0.0022 17.0 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EGO20261.1 - 0.0037 17.2 0.2 0.035 14.0 0.2 2.4 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 EGO20261.1 - 0.0039 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EGO20261.1 - 0.04 13.1 0.0 0.11 11.6 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FRB_dom PF08771.11 EGO20261.1 - 0.091 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain AA_permease_2 PF13520.6 EGO20263.1 - 4.4e-46 157.6 60.1 5.5e-46 157.3 60.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO20263.1 - 1.2e-19 70.3 53.7 1.7e-19 69.8 53.7 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.11 EGO20263.1 - 2.3 7.4 7.3 0.088 12.0 0.4 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 zf-MYND PF01753.18 EGO20264.1 - 1.5e-10 41.0 14.5 3.4e-10 39.8 14.4 1.7 1 1 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGO20264.1 - 1.7 8.6 14.5 5.2 7.0 14.5 1.8 1 1 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 EGO20264.1 - 3.4 8.0 14.7 6 7.3 13.7 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 EGO20264.1 - 5.9 4.6 7.9 6.4 4.5 7.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Glyco_hydro_79C PF16862.5 EGO20265.1 - 1.1e-20 74.4 0.3 4.8e-20 72.4 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain ABM PF03992.16 EGO20266.1 - 0.00098 19.2 0.1 0.53 10.4 0.1 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ACOX PF01756.19 EGO20267.1 - 1.9e-39 135.1 0.0 3.2e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGO20267.1 - 2.3e-07 30.9 0.0 9.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGO20267.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGO20267.1 - 0.081 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Glyco_hydro_79C PF16862.5 EGO20268.1 - 3.1e-20 73.0 0.1 1.5e-19 70.8 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain La PF05383.17 EGO20269.1 - 1.3e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGO20269.1 - 3.4e-05 23.6 0.1 5.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STE3 PF02076.15 EGO20273.1 - 1.1e-93 313.6 22.3 1.3e-93 313.4 22.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor Ycf9 PF01737.17 EGO20273.1 - 0.54 10.2 0.0 0.54 10.2 0.0 3.7 5 0 0 5 5 5 0 YCF9 FeoB_associated PF12669.7 EGO20273.1 - 1.6 9.2 4.7 1.7 9.1 1.6 2.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein WD40 PF00400.32 EGO20274.1 - 4.8e-51 169.6 22.0 3.2e-09 37.3 0.0 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20274.1 - 5.1e-20 71.6 0.4 0.013 15.8 0.0 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 EGO20274.1 - 4.8e-07 30.3 0.0 1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGO20274.1 - 3e-06 27.3 0.0 7.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EGO20274.1 - 3.9e-06 26.1 5.0 1.1 8.2 0.0 5.3 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO20274.1 - 5.7e-05 22.9 2.1 31 4.7 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4082 PF13313.6 EGO20274.1 - 0.003 17.6 2.6 1.4 8.9 0.1 4.0 2 2 1 4 4 4 1 Domain of unknown function (DUF4082) APS_kinase PF01583.20 EGO20274.1 - 0.022 14.7 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Nup160 PF11715.8 EGO20274.1 - 0.03 13.0 5.5 4.5 5.8 0.0 4.5 4 2 2 6 6 6 0 Nucleoporin Nup120/160 AAA_22 PF13401.6 EGO20274.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGO20274.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGO20274.1 - 0.098 13.1 0.1 0.61 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGO20274.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EGO20274.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EGO20274.1 - 0.14 12.6 0.1 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ESPR PF13018.6 EGO20274.1 - 0.16 11.8 0.1 1.4e+02 2.4 0.0 3.6 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system Frtz PF11768.8 EGO20274.1 - 0.2 9.9 0.0 40 2.4 0.0 3.5 3 2 0 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5053 PF16476.5 EGO20276.1 - 0.0033 17.0 0.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5053) Peptidase_S9 PF00326.21 EGO20277.1 - 8.5e-29 100.5 0.0 1.3e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGO20277.1 - 0.0015 17.8 0.2 0.059 12.6 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO20277.1 - 0.0022 17.7 0.0 0.076 12.7 0.2 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGO20277.1 - 0.004 17.0 0.2 0.019 14.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EGO20277.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 EGO20277.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Aconitase PF00330.20 EGO20278.1 - 1.6e-152 508.8 0.0 1.9e-152 508.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO20278.1 - 5.6e-45 152.9 0.0 1.1e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Importin_rep PF18773.1 EGO20279.1 - 1.8e-10 40.3 1.0 1e-09 37.9 0.2 2.5 2 0 0 2 2 2 1 Importin 13 repeat Xpo1 PF08389.12 EGO20279.1 - 2.8e-07 30.7 0.9 3e-05 24.1 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein Importin_rep_3 PF18806.1 EGO20279.1 - 3.9e-06 26.8 0.2 2.6e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Importin 13 repeat IBN_N PF03810.19 EGO20279.1 - 0.00029 20.7 0.0 0.00083 19.2 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain TetR_C_30 PF17939.1 EGO20279.1 - 0.12 12.6 0.4 38 4.5 0.0 3.3 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Tyr-DNA_phospho PF06087.12 EGO20282.1 - 1.3e-52 179.1 0.0 5.1e-52 177.2 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EGO20282.1 - 0.022 14.7 0.3 0.022 14.7 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif PLDc_2 PF13091.6 EGO20282.1 - 0.099 12.5 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain DUF2183 PF09949.9 EGO20286.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) HTH_33 PF13592.6 EGO20286.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Sugar_tr PF00083.24 EGO20287.1 - 4.9e-91 305.9 25.9 5.7e-91 305.6 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO20287.1 - 2.2e-18 66.3 42.0 3.8e-14 52.4 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B_2 PF12706.7 EGO20288.1 - 2.4e-29 102.3 0.1 3.3e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGO20288.1 - 2e-08 34.3 0.0 5.1e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO20288.1 - 0.19 11.7 2.2 1.4 8.9 1.2 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily adh_short PF00106.25 EGO20290.1 - 2.7e-29 102.0 0.0 1.2e-27 96.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20290.1 - 1e-19 71.0 0.0 7.2e-18 65.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20290.1 - 4.6e-09 36.4 0.0 7.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO20290.1 - 0.00072 19.1 0.3 0.0011 18.4 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alpha_kinase PF02816.18 EGO20291.1 - 3.2e-07 30.7 0.0 3.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF2689 PF10894.8 EGO20291.1 - 0.093 12.5 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) WD40 PF00400.32 EGO20298.1 - 7.7e-20 70.9 8.7 8e-09 36.0 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20298.1 - 1.4e-07 31.7 0.1 0.028 14.7 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO20298.1 - 0.00078 18.5 0.1 0.22 10.5 0.1 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5308 PF17233.2 EGO20299.1 - 0.11 12.7 1.5 0.16 12.2 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CDC45 PF02724.14 EGO20299.1 - 0.42 8.8 12.9 0.51 8.6 12.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1283 PF06932.11 EGO20299.1 - 1.9 8.7 12.6 0.36 11.1 7.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1283) BSMAP PF12280.8 EGO20299.1 - 7.6 6.7 9.9 23 5.1 9.9 1.7 1 1 0 1 1 1 0 Brain specific membrane anchored protein CxC1 PF18802.1 EGO20300.1 - 1.7e-05 24.9 0.2 2.7e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGO20300.1 - 0.086 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Sugar_tr PF00083.24 EGO20301.1 - 1.8e-89 300.7 16.7 2e-89 300.5 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO20301.1 - 1.1e-29 103.5 26.4 4.5e-17 62.0 7.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 EGO20301.1 - 1.6 8.8 8.2 0.11 12.5 2.2 2.3 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 EGO20301.1 - 1.9 8.4 7.5 0.39 10.6 3.0 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain Sugar_tr PF00083.24 EGO20303.1 - 4.7e-86 289.4 17.7 5.4e-86 289.2 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO20303.1 - 2.6e-20 72.6 34.4 2.5e-10 39.8 17.4 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 EGO20303.1 - 0.24 11.9 0.0 0.43 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EGO20304.1 - 3.4e-92 309.7 24.6 4e-92 309.5 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO20304.1 - 5.9e-18 64.9 44.4 4.9e-13 48.7 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_38N PF01074.22 EGO20307.1 - 6e-77 258.9 0.3 8.7e-77 258.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGO20307.1 - 5.8e-49 167.1 0.0 8.8e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGO20307.1 - 4.4e-26 90.9 0.0 1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGO20307.1 - 4.1e-07 30.0 0.0 7.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EGO20307.1 - 7.6e-05 22.1 0.0 0.00033 20.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Tfb5 PF06331.12 EGO20307.1 - 0.19 11.7 0.0 33 4.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 GPI-anchored PF10342.9 EGO20309.1 - 0.055 14.2 0.1 0.14 12.9 0.1 1.8 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dynamin_M PF01031.20 EGO20310.1 - 1.6e-34 119.5 0.2 8.6e-34 117.1 0.2 2.1 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGO20310.1 - 7.5e-21 74.9 0.0 4e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EGO20310.1 - 1e-10 41.6 0.1 3e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO20310.1 - 0.0013 18.8 0.0 0.012 15.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase WD40 PF00400.32 EGO20311.1 - 0.0017 19.1 1.5 1.6 9.7 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20311.1 - 0.06 13.6 0.0 32 4.9 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L14 PF00238.19 EGO20312.1 - 2.3e-35 121.3 0.0 2.8e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNB PF00773.19 EGO20313.1 - 4.4e-96 322.0 0.0 6.4e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EGO20313.1 - 8e-27 93.8 0.0 1.7e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EGO20313.1 - 1.5e-25 88.9 2.0 1.5e-25 88.9 2.0 1.7 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 EGO20313.1 - 5.1e-15 55.3 0.1 3.1e-14 52.8 0.0 2.5 3 0 0 3 3 3 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EGO20313.1 - 1.6e-10 41.0 5.0 0.00011 22.2 0.0 4.8 5 0 0 5 5 5 3 Cold shock domain PIN_4 PF13638.6 EGO20313.1 - 3.1e-09 37.2 0.0 8.5e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 PIN domain OB_RNB PF08206.11 EGO20313.1 - 0.073 12.8 2.8 0.22 11.2 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain His_Phos_2 PF00328.22 EGO20316.1 - 8.1e-15 55.1 0.0 2e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 EGO20317.1 - 4.2e-26 91.7 24.2 6.6e-26 91.1 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_10 PF05971.12 EGO20320.1 - 8.9e-54 182.8 0.2 1e-53 182.6 0.2 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGO20320.1 - 0.00035 20.1 0.0 0.00083 18.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO20320.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TrmK PF04816.12 EGO20320.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 EGO20320.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UCR_hinge PF02320.16 EGO20321.1 - 1.3e-22 79.7 5.6 1.3e-22 79.7 5.6 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF3306 PF11748.8 EGO20321.1 - 0.038 14.9 1.4 0.049 14.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) F-box PF00646.33 EGO20322.1 - 0.85 9.6 6.1 0.21 11.5 2.1 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EGO20322.1 - 1.4 8.9 9.4 0.057 13.3 2.0 2.4 2 1 0 2 2 2 0 F-box-like Acyl-CoA_dh_M PF02770.19 EGO20323.1 - 0.00099 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain zf-CCHC PF00098.23 EGO20324.1 - 0.00023 21.1 1.8 0.00048 20.1 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 EGO20325.1 - 0.00014 22.4 0.0 0.00014 22.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO20325.1 - 0.00052 20.5 0.0 0.00055 20.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 EGO20326.1 - 7.5e-13 48.3 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RE_HaeIII PF09556.10 EGO20326.1 - 0.086 11.9 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease Retrotran_gag_2 PF14223.6 EGO20327.1 - 2.6e-09 36.9 0.1 3.5e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO20327.1 - 0.0082 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) AAA_11 PF13086.6 EGO20329.1 - 2.9e-08 33.8 0.1 1.9e-06 27.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO20329.1 - 3.2e-07 30.3 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO20329.1 - 9.1e-07 29.3 0.1 9.3e-07 29.3 0.1 1.2 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGO20329.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 EGO20329.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 EGO20329.1 - 0.028 14.1 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase AAA PF00004.29 EGO20329.1 - 0.032 14.6 1.0 0.038 14.4 1.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO20329.1 - 0.045 13.9 0.0 0.057 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO20329.1 - 0.056 14.0 0.0 0.065 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGO20329.1 - 0.072 12.7 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EGO20329.1 - 0.13 12.1 0.1 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EGO20329.1 - 0.13 12.6 0.1 0.17 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGO20329.1 - 0.13 12.0 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4292 PF14125.6 EGO20329.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) OPT PF03169.15 EGO20331.1 - 9.4e-89 298.7 39.2 1.2e-88 298.4 39.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dynamin_M PF01031.20 EGO20332.1 - 4.7e-32 111.4 0.2 4.5e-31 108.1 0.2 2.2 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGO20332.1 - 2.7e-23 82.8 0.0 5.8e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGO20332.1 - 1.6e-10 41.0 0.4 5.4e-10 39.3 0.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO20332.1 - 0.00013 22.0 0.1 0.0019 18.2 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO20332.1 - 0.023 15.1 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGO20332.1 - 0.03 14.2 0.6 5.1 7.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF2408 PF10303.9 EGO20332.1 - 0.12 12.9 0.4 4.7 7.8 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) ABC_tran PF00005.27 EGO20332.1 - 0.12 12.8 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PMSR PF01625.21 EGO20333.1 - 4e-58 195.9 1.7 4.6e-58 195.7 1.1 1.4 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase Amidohydro_1 PF01979.20 EGO20336.1 - 1.6e-26 93.5 0.0 3e-26 92.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO20336.1 - 7.6e-17 61.9 0.0 2.3e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 EGO20336.1 - 0.041 14.2 1.1 0.11 12.9 0.8 1.9 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain NAD_binding_4 PF07993.12 EGO20336.1 - 0.16 11.1 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Pkinase_fungal PF17667.1 EGO20337.1 - 9e-09 34.6 0.0 1.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase gag-asp_proteas PF13975.6 EGO20339.1 - 1e-06 29.2 0.0 1.2e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO20339.1 - 1.1e-06 28.5 0.0 1.2e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO20339.1 - 1.6e-05 25.4 0.0 2.4e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease PLDc_3 PF13918.6 EGO20340.1 - 0.08 12.6 0.0 0.08 12.6 0.0 1.0 1 0 0 1 1 1 0 PLD-like domain Rap_GAP PF02145.15 EGO20341.1 - 5.2e-47 159.8 0.0 6.9e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Glyco_hydro_3 PF00933.21 EGO20343.1 - 1.8e-87 293.7 0.4 2.5e-87 293.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Chlam_vir PF05475.11 EGO20343.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Pgp3 C-terminal domain RRM_1 PF00076.22 EGO20344.1 - 2.9e-35 119.9 0.2 2.7e-16 59.1 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO20344.1 - 4.6e-11 42.7 0.1 1.9e-06 27.9 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGO20344.1 - 2.3e-05 24.3 0.0 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 EGO20344.1 - 0.00023 20.8 0.3 0.088 12.5 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_3 PF08777.11 EGO20344.1 - 0.0074 16.3 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif COG7 PF10191.9 EGO20345.1 - 1.9e-80 271.2 10.4 6e-48 163.7 4.6 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) SPO11_like PF03533.14 EGO20345.1 - 0.0059 16.7 0.2 0.3 11.2 0.0 2.7 2 0 0 2 2 2 1 SPO11 homologue AbiH PF14253.6 EGO20345.1 - 0.05 13.5 0.5 0.2 11.5 0.4 2.1 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH LIM PF00412.22 EGO20346.1 - 7.8e-17 61.3 13.7 2.3e-13 50.2 7.2 2.4 2 1 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 EGO20346.1 - 0.00088 18.8 14.8 2.2 8.0 0.1 4.7 5 0 0 5 5 5 4 Ubiquitin-Binding Zinc Finger zf-CCHC_5 PF14787.6 EGO20346.1 - 0.053 13.2 6.2 1.1 9.0 0.0 4.2 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger zf-ACC PF17848.1 EGO20346.1 - 0.1 12.7 6.8 6 7.0 0.3 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF3039 PF11238.8 EGO20346.1 - 0.15 11.8 7.1 1.6 8.5 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3039) YacG PF03884.14 EGO20346.1 - 0.21 11.4 7.2 8.3 6.2 0.1 3.4 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Zn_Tnp_IS1595 PF12760.7 EGO20346.1 - 3.9 7.5 22.8 0.47 10.5 6.7 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain HEAT PF02985.22 EGO20347.1 - 1.8e-08 33.9 10.5 0.45 10.9 0.0 9.6 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 EGO20347.1 - 1e-06 29.0 5.7 1.9 9.0 0.0 7.7 8 1 2 10 10 10 1 HEAT repeats HEAT_EZ PF13513.6 EGO20347.1 - 3.8e-05 24.1 18.6 0.0042 17.6 0.1 8.6 10 1 2 12 12 12 1 HEAT-like repeat UME PF08064.13 EGO20347.1 - 0.0003 20.6 1.6 0.44 10.5 0.1 5.1 5 0 0 5 5 5 1 UME (NUC010) domain Arm PF00514.23 EGO20347.1 - 0.00068 19.6 3.8 0.0049 16.9 0.1 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat TctA PF01970.16 EGO20347.1 - 0.011 14.5 0.2 0.076 11.7 0.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Syja_N PF02383.18 EGO20348.1 - 1.5e-76 257.8 0.0 2.4e-76 257.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Chromo PF00385.24 EGO20350.1 - 2.4e-05 24.1 0.1 3.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rft-1 PF04506.13 EGO20352.1 - 1.6e-128 429.7 11.6 1.9e-128 429.4 11.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EGO20352.1 - 0.00014 21.2 8.9 0.0026 17.0 0.1 3.9 4 0 0 4 4 4 2 Polysaccharide biosynthesis protein MtN3_slv PF03083.16 EGO20352.1 - 0.034 14.2 1.4 0.39 10.8 0.4 3.0 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SAP PF02037.27 EGO20353.1 - 2e-05 24.2 0.7 3.1e-05 23.6 0.7 1.3 1 0 0 1 1 1 1 SAP domain Metallothi_Euk2 PF12809.7 EGO20354.1 - 0.062 13.6 8.5 0.11 12.8 8.5 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein AAA_12 PF13087.6 EGO20355.1 - 4.6e-57 192.9 0.0 6e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO20355.1 - 3.4e-23 82.8 0.6 5.1e-23 82.2 0.6 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGO20355.1 - 9.9e-05 22.2 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGO20355.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO20355.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EGO20355.1 - 0.082 12.7 0.1 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF1152 PF06626.12 EGO20357.1 - 0.23 10.6 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) zf-RanBP PF00641.18 EGO20358.1 - 0.016 14.5 15.6 0.24 10.8 3.5 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others APC1_C PF18122.1 EGO20359.1 - 1.6e-36 125.7 1.0 2.5e-35 121.9 0.1 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EGO20359.1 - 3.9e-05 24.2 0.7 0.00031 21.3 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EGO20359.1 - 0.17 12.4 11.6 0.46 11.0 0.0 5.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat DAHP_synth_1 PF00793.20 EGO20360.1 - 5.6e-100 333.7 0.0 7.2e-100 333.4 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family FAD-oxidase_C PF02913.19 EGO20360.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain PIH1 PF08190.12 EGO20361.1 - 4.3e-22 78.3 0.3 1.5e-21 76.6 0.3 1.7 1 1 0 1 1 1 1 PIH1 N-terminal domain Peptidase_C65 PF10275.9 EGO20362.1 - 1.8e-64 217.5 0.0 2.1e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EGO20362.1 - 1.9e-05 25.2 0.0 0.024 15.1 0.0 2.3 2 0 0 2 2 2 2 OTU-like cysteine protease TPR_10 PF13374.6 EGO20363.1 - 8.1e-98 318.0 13.9 1.5e-11 43.8 0.0 9.1 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 EGO20363.1 - 1.6e-93 307.0 32.8 1.5e-18 66.8 0.0 7.0 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGO20363.1 - 7.1e-45 147.8 23.4 4.1e-06 26.4 0.0 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGO20363.1 - 7.2e-44 145.9 34.4 2.9e-06 26.9 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGO20363.1 - 8.5e-37 122.3 26.8 4.3e-05 23.3 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGO20363.1 - 1.4e-33 112.2 27.8 0.0001 22.3 0.0 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 EGO20363.1 - 2.1e-18 65.4 13.6 0.22 12.4 0.1 8.2 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 EGO20363.1 - 1.5e-17 62.3 0.0 0.007 16.9 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO20363.1 - 8.6e-17 61.5 18.8 0.00012 22.6 4.2 6.7 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO20363.1 - 2.3e-16 60.1 2.9 3.7e-11 43.0 0.1 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 EGO20363.1 - 4e-15 56.1 15.1 0.00029 21.3 0.4 6.5 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGO20363.1 - 5.5e-15 54.6 16.1 1.8 9.1 0.0 9.6 9 0 0 9 9 9 2 Tetratricopeptide repeat PPR PF01535.20 EGO20363.1 - 4.4e-11 42.2 10.0 0.17 12.2 0.0 7.9 9 0 0 9 9 9 3 PPR repeat ANAPC3 PF12895.7 EGO20363.1 - 3.8e-08 33.4 18.3 0.071 13.3 0.5 6.4 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGO20363.1 - 9.8e-08 32.2 24.0 2.5 8.9 0.1 8.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGO20363.1 - 1.1e-07 31.7 22.2 0.18 11.8 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO20363.1 - 2.2e-07 30.5 30.1 0.16 11.7 0.2 8.5 9 1 0 9 9 9 4 TPR repeat SRP68 PF16969.5 EGO20363.1 - 1.7e-05 24.0 8.3 4.1 6.3 0.0 6.3 5 1 2 7 7 7 2 RNA-binding signal recognition particle 68 Coatomer_E PF04733.14 EGO20363.1 - 2.3e-05 24.0 5.1 0.72 9.2 0.0 6.1 1 1 7 8 8 8 1 Coatomer epsilon subunit DUF4919 PF16266.5 EGO20363.1 - 4e-05 23.6 1.7 1.4 8.9 0.0 4.8 3 3 2 5 5 5 1 Domain of unknown function (DUF4919) 14-3-3 PF00244.20 EGO20363.1 - 0.00023 20.7 0.2 2 7.8 0.3 4.4 2 2 3 6 6 6 1 14-3-3 protein Wzy_C_2 PF11846.8 EGO20363.1 - 0.0076 16.2 6.9 8.1 6.3 0.0 5.6 4 2 1 5 5 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_5 PF12688.7 EGO20363.1 - 0.0092 16.2 9.5 1.4 9.2 0.1 5.4 3 1 2 6 6 6 1 Tetratrico peptide repeat MIT PF04212.18 EGO20363.1 - 0.012 15.6 16.5 0.17 12.0 0.2 6.0 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain Tcf25 PF04910.14 EGO20363.1 - 0.019 14.1 0.7 12 4.8 0.0 4.0 2 2 2 4 4 4 0 Transcriptional repressor TCF25 DUF5112 PF17139.4 EGO20363.1 - 0.036 13.6 2.8 6.7 6.1 1.5 4.4 4 2 0 5 5 5 0 Domain of unknown function (DUF5112) DUF1897 PF09005.10 EGO20363.1 - 0.054 13.0 13.9 4.3 6.9 0.2 6.2 7 0 0 7 7 7 0 Domain of unknown function (DUF1897) PNKP-ligase_C PF16536.5 EGO20363.1 - 0.058 13.7 0.6 9.2 6.6 0.0 3.3 3 0 0 3 3 2 0 PNKP adenylyltransferase domain, C-terminal region TPR_20 PF14561.6 EGO20363.1 - 0.16 12.3 3.2 76 3.7 0.1 5.2 4 2 0 4 4 3 0 Tetratricopeptide repeat FlaE PF07559.14 EGO20363.1 - 0.19 12.3 0.5 7.5 7.2 0.2 3.3 2 1 0 2 2 2 0 Flagellar basal body protein FlaE Mad3_BUB1_I PF08311.12 EGO20363.1 - 3.3 7.7 10.4 33 4.5 0.1 5.2 7 0 0 7 7 6 0 Mad3/BUB1 homology region 1 zf-CCHC PF00098.23 EGO20364.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO20364.1 - 0.0083 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO20364.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain zinc_ribbon_2 PF13240.6 EGO20366.1 - 0.67 9.8 7.1 0.4 10.5 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.24 EGO20366.1 - 7.7 6.8 8.8 72 3.7 8.7 2.4 1 1 1 2 2 2 0 B-box zinc finger Beta-lactamase PF00144.24 EGO20369.1 - 1.8e-42 145.8 0.2 2.4e-42 145.4 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 EGO20370.1 - 7.2e-36 124.1 0.0 1.2e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Bromo_TP PF07524.13 EGO20371.1 - 1.5e-05 24.9 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated SRAP PF02586.14 EGO20372.1 - 7.6e-65 218.5 0.1 9.5e-65 218.2 0.1 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) AMP-binding PF00501.28 EGO20373.1 - 3.6e-16 58.8 0.0 4.4e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 EGO20373.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter NAD_binding_4 PF07993.12 EGO20374.1 - 2.2e-30 105.7 0.0 3.2e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO20374.1 - 2.1e-10 39.8 0.1 2.6e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EGO20374.1 - 3.8e-08 33.1 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGO20374.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 EGO20374.1 - 0.05 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PP-binding PF00550.25 EGO20374.1 - 0.069 13.5 0.0 0.39 11.1 0.0 2.2 1 1 0 1 1 1 0 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EGO20374.1 - 0.15 11.4 0.0 1.4 8.3 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase AMP-binding PF00501.28 EGO20375.1 - 2.1e-30 105.7 0.0 2.5e-29 102.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGO20375.1 - 5.9e-29 101.0 0.0 8.4e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGO20375.1 - 3.4e-07 30.0 0.0 6.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO20375.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PP-binding PF00550.25 EGO20375.1 - 0.11 12.9 0.0 0.52 10.7 0.0 2.1 1 1 0 1 1 1 0 Phosphopantetheine attachment site Amidohydro_3 PF07969.11 EGO20377.1 - 8.1e-69 233.3 0.0 4.9e-46 158.2 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO20377.1 - 2e-08 33.9 0.0 1.3e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family TFA2_Winged_2 PF18121.1 EGO20378.1 - 6.8e-20 70.5 0.1 1.3e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EGO20378.1 - 8.6e-16 58.0 0.8 5.4e-15 55.4 0.3 2.4 2 0 0 2 2 2 1 TFIIE beta subunit core domain Methyltransf_31 PF13847.6 EGO20378.1 - 0.0079 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pan3_PK PF18101.1 EGO20379.1 - 9e-65 216.8 0.0 1.4e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGO20379.1 - 7.2e-06 25.6 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO20379.1 - 0.00028 20.2 0.1 0.00043 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase T3RM_EcoP15I_C PF18273.1 EGO20379.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain LSM PF01423.22 EGO20383.1 - 3.5e-13 49.0 0.0 4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.6 EGO20384.1 - 2.6e-17 62.9 13.1 1.8e-11 44.2 0.0 7.2 7 1 1 8 8 8 3 HEAT-like repeat HEAT PF02985.22 EGO20384.1 - 3.2e-15 54.9 14.2 0.00026 21.0 0.0 10.6 12 0 0 12 12 10 2 HEAT repeat HEAT_2 PF13646.6 EGO20384.1 - 1.3e-11 44.8 5.3 0.081 13.3 0.0 7.6 3 2 3 7 7 7 4 HEAT repeats IBN_N PF03810.19 EGO20384.1 - 2e-10 40.4 0.4 4.6e-09 36.1 0.5 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 EGO20384.1 - 1.1e-06 28.4 11.4 0.0053 16.8 0.1 6.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGO20384.1 - 0.00048 18.8 3.1 0.052 12.1 0.0 3.5 2 2 0 2 2 2 1 Adaptin N terminal region MMS19_C PF12460.8 EGO20384.1 - 0.00059 19.1 2.5 0.26 10.3 0.0 3.5 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EGO20384.1 - 0.0011 19.0 3.5 1.1 9.1 0.0 4.3 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EGO20384.1 - 0.0071 16.4 3.5 0.02 14.9 0.0 3.5 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO20384.1 - 0.0083 15.7 0.2 9.9 5.7 0.1 4.3 2 2 3 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.9 EGO20384.1 - 0.024 13.1 0.7 0.084 11.4 0.1 2.0 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit TIP120 PF08623.10 EGO20384.1 - 0.044 13.6 0.1 0.26 11.0 0.0 2.4 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Lon_C PF05362.13 EGO20385.1 - 1.7e-66 223.7 0.4 2.7e-66 223.0 0.4 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGO20385.1 - 1.6e-21 77.1 0.0 4.6e-21 75.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO20385.1 - 3.5e-11 43.3 0.0 7.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 EGO20385.1 - 2.1e-07 31.0 0.0 4.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EGO20385.1 - 5.3e-07 29.5 0.0 2.6e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EGO20385.1 - 1.5e-05 25.2 0.0 8.7e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGO20385.1 - 0.001 19.5 3.1 0.002 18.6 0.0 2.7 2 2 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 EGO20385.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EGO20385.1 - 0.0074 16.0 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGO20385.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO20385.1 - 0.014 15.6 1.0 0.17 12.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGO20385.1 - 0.016 15.1 0.0 0.051 13.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGO20385.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGO20385.1 - 0.036 14.6 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 EGO20385.1 - 0.048 12.9 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EGO20385.1 - 0.098 12.2 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGO20385.1 - 0.11 11.9 0.0 0.49 9.7 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SKI PF01202.22 EGO20385.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase RNA_helicase PF00910.22 EGO20385.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGO20385.1 - 0.19 12.1 0.8 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsbRD_N PF14361.6 EGO20385.1 - 0.49 11.1 3.2 7.1 7.4 0.1 3.0 1 1 1 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain adh_short PF00106.25 EGO20387.1 - 2.3e-32 112.1 0.0 3.7e-26 91.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20387.1 - 1.8e-18 67.0 0.0 4.7e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20387.1 - 6.8e-07 29.4 0.0 9.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO20387.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO20387.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO20387.1 - 0.02 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding TPR_19 PF14559.6 EGO20387.1 - 0.086 13.4 0.3 0.18 12.3 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ArenaCapSnatch PF17296.2 EGO20387.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Arenavirus cap snatching domain Sacchrp_dh_NADP PF03435.18 EGO20387.1 - 0.19 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1192 PF06698.11 EGO20388.1 - 0.038 14.0 1.1 0.12 12.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 EGO20388.1 - 0.073 12.4 2.3 0.12 11.7 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EGO20388.1 - 0.099 12.7 9.4 0.16 12.0 9.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EGO20388.1 - 0.12 11.3 12.7 0.18 10.6 12.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 EGO20388.1 - 0.14 12.6 9.0 0.33 11.4 8.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Fmp27_WPPW PF10359.9 EGO20388.1 - 0.16 10.8 4.4 0.23 10.2 4.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Fez1 PF06818.15 EGO20388.1 - 0.17 12.3 10.1 0.33 11.4 10.1 1.4 1 0 0 1 1 1 0 Fez1 RRP36 PF06102.12 EGO20388.1 - 0.2 11.6 7.1 0.4 10.6 7.1 1.6 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Atg14 PF10186.9 EGO20388.1 - 0.23 10.5 7.9 0.33 10.0 7.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 EGO20388.1 - 0.25 10.0 7.3 0.34 9.5 7.3 1.1 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.13 EGO20388.1 - 0.41 10.7 9.6 0.72 10.0 9.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein LPP PF04728.13 EGO20388.1 - 0.42 11.0 4.1 0.87 10.0 0.1 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF2968 PF11180.8 EGO20388.1 - 0.69 9.5 10.1 1.2 8.8 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FapA PF03961.13 EGO20388.1 - 0.69 8.5 5.0 0.95 8.0 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A betaPIX_CC PF16523.5 EGO20388.1 - 0.98 9.3 11.0 1.9 8.4 11.0 1.5 1 0 0 1 1 1 0 betaPIX coiled coil DUF4795 PF16043.5 EGO20388.1 - 1.2 8.7 11.6 4 7.0 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Cluap1 PF10234.9 EGO20388.1 - 2 7.7 11.5 3.1 7.1 11.5 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6_N PF17675.1 EGO20388.1 - 2.3 8.8 13.5 4.2 7.9 13.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HAUS6_N PF14661.6 EGO20388.1 - 2.3 7.7 7.8 4 7.0 7.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus zf-CCHC_3 PF13917.6 EGO20393.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO20393.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO20393.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO20393.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Plavaka PF18759.1 EGO20395.1 - 1.9e-15 56.9 0.5 1.6e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 Plavaka transposase Choline_kinase PF01633.20 EGO20396.1 - 5.2e-48 163.5 0.0 7.4e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGO20396.1 - 6.3e-11 42.7 0.0 9.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ldh_1_C PF02866.18 EGO20398.1 - 5.9e-42 143.4 0.1 7.9e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGO20398.1 - 1.6e-34 119.0 0.3 3.5e-34 117.9 0.3 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGO20398.1 - 0.028 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ELP6 PF09807.9 EGO20401.1 - 1.7e-19 70.2 0.0 6.8e-19 68.3 0.0 1.7 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 EGO20401.1 - 0.0019 17.8 0.0 0.0046 16.5 0.0 1.6 1 1 0 1 1 1 1 Elongator subunit Iki1 Abhydrolase_3 PF07859.13 EGO20402.1 - 5.3e-25 88.5 0.0 6.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO20402.1 - 4.1e-16 58.8 0.0 5.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EGO20402.1 - 0.0023 18.6 0.1 0.0037 17.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGO20402.1 - 0.019 14.8 0.2 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 EGO20402.1 - 0.037 13.7 0.0 0.088 12.4 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Metallophos PF00149.28 EGO20403.1 - 3e-11 44.2 0.7 3e-11 44.2 0.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF3220 PF11516.8 EGO20403.1 - 0.026 14.7 0.3 0.096 12.9 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3120) Ish1 PF10281.9 EGO20404.1 - 4.9e-67 221.9 33.8 2.5e-12 46.9 0.6 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein LEA_4 PF02987.16 EGO20404.1 - 4.2e-09 36.3 52.6 0.0002 21.4 7.4 6.0 4 1 1 5 5 5 5 Late embryogenesis abundant protein SAP PF02037.27 EGO20404.1 - 0.012 15.4 0.0 0.24 11.2 0.0 3.2 3 0 0 3 3 3 0 SAP domain TryThrA_C PF12319.8 EGO20404.1 - 0.29 10.6 37.4 0.054 13.0 8.6 4.7 3 2 1 4 4 4 0 Tryptophan-Threonine-rich plasmodium antigen C terminal zf-CCHC PF00098.23 EGO20405.1 - 2.6e-07 30.4 2.9 5.1e-07 29.5 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO20405.1 - 0.00018 21.7 6.3 0.0019 18.4 6.3 2.4 1 1 0 1 1 1 1 Retrotransposon gag protein AA_permease_2 PF13520.6 EGO20408.1 - 1.9e-59 201.6 40.8 2.4e-59 201.3 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO20408.1 - 9.4e-16 57.5 32.8 1.3e-15 57.0 32.8 1.2 1 0 0 1 1 1 1 Amino acid permease PDZ_5 PF17817.1 EGO20409.1 - 0.041 14.2 0.1 13 6.1 0.0 2.6 2 0 0 2 2 2 0 PDZ domain Aldo_ket_red PF00248.21 EGO20411.1 - 4.4e-48 164.0 0.0 4.5e-46 157.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family AAA_18 PF13238.6 EGO20412.1 - 7.7e-33 113.8 0.2 5.1e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGO20412.1 - 1.4e-05 25.5 0.2 9.4e-05 22.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EGO20412.1 - 4.7e-05 23.8 0.1 9.1e-05 22.9 0.1 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO20412.1 - 4.9e-05 23.6 0.1 0.00017 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO20412.1 - 5.7e-05 23.4 0.1 0.00028 21.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 EGO20412.1 - 6.7e-05 22.8 0.4 0.3 10.9 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_33 PF13671.6 EGO20412.1 - 0.00011 22.4 0.1 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 EGO20412.1 - 0.00098 19.3 0.4 0.01 16.0 0.4 2.0 1 1 0 1 1 1 1 Shikimate kinase ATPase PF06745.13 EGO20412.1 - 0.0012 18.2 1.8 0.23 10.8 0.1 2.1 2 0 0 2 2 2 2 KaiC Thymidylate_kin PF02223.17 EGO20412.1 - 0.0014 18.4 0.2 1.5 8.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase ADK PF00406.22 EGO20412.1 - 0.0025 17.9 0.0 0.078 13.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase DUF218 PF02698.17 EGO20412.1 - 0.0032 17.5 0.8 0.0095 16.0 0.4 2.0 2 1 0 2 2 2 1 DUF218 domain Rad17 PF03215.15 EGO20412.1 - 0.0032 17.4 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGO20412.1 - 0.006 17.0 0.1 0.0085 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 EGO20412.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EGO20412.1 - 0.012 15.6 1.5 0.072 13.0 0.3 2.2 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EGO20412.1 - 0.012 15.3 0.1 0.019 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGO20412.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EGO20412.1 - 0.016 14.5 0.1 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EGO20412.1 - 0.018 15.4 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGO20412.1 - 0.026 15.1 0.2 0.049 14.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 EGO20412.1 - 0.028 13.6 0.3 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGO20412.1 - 0.039 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EGO20412.1 - 0.053 13.6 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGO20412.1 - 0.063 13.3 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO20412.1 - 0.079 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 EGO20412.1 - 0.08 12.0 0.5 0.13 11.3 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 EGO20412.1 - 0.1 11.6 0.5 0.4 9.6 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CoaE PF01121.20 EGO20412.1 - 0.11 12.2 0.4 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase NACHT PF05729.12 EGO20412.1 - 0.15 12.0 0.1 0.45 10.4 0.0 1.8 2 1 0 2 2 2 0 NACHT domain OATP PF03137.20 EGO20414.1 - 0.002 16.5 4.9 0.0028 16.0 0.7 2.4 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Membr_traf_MHD PF10540.9 EGO20415.1 - 2.3e-24 86.2 0.0 1.3e-11 44.9 0.0 2.7 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EGO20415.1 - 8e-09 35.7 0.0 2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain HSP70 PF00012.20 EGO20416.1 - 3.1e-81 273.4 4.6 3.1e-81 273.4 4.6 2.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGO20416.1 - 2.1e-05 23.5 1.5 8e-05 21.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 EGO20416.1 - 0.013 15.0 0.2 0.043 13.3 0.1 1.9 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Skp1_POZ PF03931.15 EGO20416.1 - 0.075 13.2 0.1 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Gp_dh_C PF02800.20 EGO20417.1 - 5.6e-71 237.3 0.0 7.5e-71 236.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGO20417.1 - 5.6e-28 97.3 0.0 1.3e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LXG PF04740.12 EGO20420.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily PPR_2 PF13041.6 EGO20421.1 - 0.00034 20.8 0.1 0.9 9.8 0.1 2.9 2 2 0 2 2 2 2 PPR repeat family PPR PF01535.20 EGO20421.1 - 4.1 7.9 6.5 49 4.5 0.0 4.2 4 1 0 4 4 4 0 PPR repeat PPR_2 PF13041.6 EGO20422.1 - 0.0017 18.5 0.0 0.01 16.0 0.0 2.4 2 1 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 EGO20422.1 - 0.0078 16.3 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain DUF4128 PF13554.6 EGO20423.1 - 0.056 13.5 0.1 0.093 12.8 0.1 1.5 1 1 0 1 1 1 0 Bacteriophage related domain of unknown function DUF3913 PF13052.6 EGO20424.1 - 0.11 12.8 0.9 0.2 12.0 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) zf-CCHC PF00098.23 EGO20425.1 - 3.5e-08 33.1 5.9 5.9e-08 32.4 5.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20425.1 - 0.014 15.4 2.5 0.029 14.3 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 EGO20427.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HEAT PF02985.22 EGO20430.1 - 3e-12 45.7 1.1 0.002 18.2 0.0 4.1 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EGO20430.1 - 3.7e-08 33.7 0.6 3.6e-05 24.1 0.1 2.9 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 EGO20430.1 - 0.00013 22.1 0.8 0.002 18.2 0.1 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 EGO20430.1 - 0.0035 15.9 1.2 0.01 14.4 1.2 1.7 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit TRF PF08558.10 EGO20430.1 - 0.023 14.3 0.9 0.33 10.5 0.1 2.0 1 1 1 2 2 2 0 Telomere repeat binding factor (TRF) Psu PF07455.11 EGO20430.1 - 0.064 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) 4HBT_3 PF13622.6 EGO20431.1 - 9.1e-53 180.0 0.0 1e-52 179.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGO20431.1 - 1.9e-20 73.0 0.0 5.2e-15 55.5 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase XPA_C PF05181.12 EGO20432.1 - 1.2e-24 86.0 2.0 2.3e-24 85.1 2.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EGO20432.1 - 0.00024 21.1 6.6 0.00024 21.1 6.6 3.1 3 0 0 3 3 3 1 XPA protein N-terminal SH3-WW_linker PF16618.5 EGO20432.1 - 0.31 11.5 7.0 0.033 14.7 2.7 1.5 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 TipAS PF07739.13 EGO20432.1 - 2 9.0 6.1 4.8 7.8 6.1 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain ANAPC_CDC26 PF10471.9 EGO20432.1 - 4.4 8.2 8.1 2.1 9.2 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Transp_cyt_pur PF02133.15 EGO20434.1 - 7.6e-26 90.9 31.9 1.1e-25 90.4 31.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WD40 PF00400.32 EGO20436.1 - 1.7e-23 82.4 24.9 4.5e-08 33.6 0.6 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20436.1 - 1.7e-12 47.4 2.1 0.034 14.4 0.0 5.8 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO20436.1 - 1.6e-05 24.7 5.6 6.4 6.9 0.0 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat VID27 PF08553.10 EGO20436.1 - 0.00012 21.3 0.1 0.1 11.6 0.0 2.1 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 EGO20436.1 - 0.00029 19.9 0.1 9.2 5.1 0.0 4.4 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EGO20436.1 - 0.0034 16.5 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.8 EGO20436.1 - 0.016 13.9 4.3 0.76 8.4 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 EGO20436.1 - 0.034 12.5 0.0 0.064 11.6 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EGO20436.1 - 0.043 12.3 0.5 6.7 5.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain eIF2A PF08662.11 EGO20436.1 - 0.081 12.8 0.0 1.3 8.9 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ribosomal_L7Ae PF01248.26 EGO20437.1 - 1.8e-26 91.7 3.1 2.3e-26 91.4 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TMEM135_C_rich PF15982.5 EGO20438.1 - 6.1e-05 23.6 2.2 0.0019 18.8 0.9 3.2 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Aim19 PF10315.9 EGO20439.1 - 1.2e-22 80.3 0.3 1.7e-22 79.9 0.3 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Abhydrolase_1 PF00561.20 EGO20440.1 - 6.3e-21 75.2 0.4 7e-14 52.1 0.4 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO20440.1 - 6e-18 65.0 0.0 8.7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO20440.1 - 8e-18 65.8 0.2 8e-18 65.8 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGO20440.1 - 1.4e-06 28.4 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 EGO20440.1 - 7.5e-05 22.6 0.5 0.5 10.1 0.2 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGO20440.1 - 0.0021 17.6 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EGO20440.1 - 0.0022 17.6 0.3 0.12 11.9 0.3 2.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGO20440.1 - 0.019 14.7 0.1 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 EGO20440.1 - 0.021 13.6 0.1 0.033 13.0 0.1 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AidB_N PF18158.1 EGO20440.1 - 0.14 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain DUF2048 PF09752.9 EGO20440.1 - 0.16 11.1 0.6 0.95 8.5 0.6 1.9 1 1 0 1 1 1 0 Abhydrolase domain containing 18 SNAPc19 PF15497.6 EGO20441.1 - 0.073 13.5 0.4 0.099 13.1 0.4 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Myb_DNA-binding PF00249.31 EGO20443.1 - 1.1e-12 47.9 0.7 1.8e-12 47.2 0.7 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO20443.1 - 2.7e-11 43.6 0.2 4.6e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGO20443.1 - 0.0022 17.9 0.2 0.0035 17.2 0.2 1.3 1 0 0 1 1 1 1 Myb DNA-binding like DUF4085 PF13315.6 EGO20443.1 - 0.043 13.5 0.1 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) SLIDE PF09111.10 EGO20443.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 SLIDE zf-LYAR PF08790.11 EGO20445.1 - 0.39 10.7 2.5 0.89 9.5 2.5 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger His_Phos_2 PF00328.22 EGO20449.1 - 9.4e-53 179.9 0.0 1.1e-52 179.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 EGO20450.1 - 4.3e-55 187.6 0.0 5.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Coatomer_WDAD PF04053.14 EGO20452.1 - 2.6e-150 501.4 0.0 6.7e-150 500.0 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGO20452.1 - 2.8e-34 116.6 12.3 4.9e-06 27.2 0.0 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20452.1 - 3.6e-06 27.2 0.0 0.04 14.2 0.0 5.6 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGO20452.1 - 0.0012 18.8 0.3 14 5.8 0.0 5.2 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EGO20452.1 - 0.0024 16.6 0.1 1.3 7.5 0.0 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 MetallophosC PF16370.5 EGO20452.1 - 0.02 15.2 0.1 0.13 12.5 0.0 2.2 1 1 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Chitin_synth_2 PF03142.15 EGO20453.1 - 4.6e-238 791.1 0.1 6.2e-238 790.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGO20453.1 - 7.7e-104 348.3 0.0 1.1e-102 344.5 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EGO20453.1 - 5.2e-18 65.0 0.0 1e-11 44.8 0.0 3.6 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EGO20453.1 - 1.2e-15 58.1 0.0 4.3e-14 53.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 EGO20453.1 - 2.6e-14 52.9 0.2 7.4e-14 51.4 0.2 1.9 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGO20453.1 - 5.8e-14 52.5 2.2 5.8e-14 52.5 2.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO20453.1 - 9.7e-08 32.0 0.0 0.00024 20.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO20453.1 - 2.6e-05 23.8 0.0 0.043 13.3 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 21 Jiv90 PF14901.6 EGO20453.1 - 0.27 11.4 0.6 6.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone NUDIX PF00293.28 EGO20454.1 - 1.6e-11 44.3 0.0 3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CS PF04969.16 EGO20455.1 - 1.3e-18 67.8 0.1 2.3e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 CS domain Xan_ur_permease PF00860.20 EGO20457.1 - 1.7e-61 208.1 37.0 8.7e-61 205.7 31.9 2.7 2 1 0 2 2 2 1 Permease family Hist_deacetyl PF00850.19 EGO20458.1 - 1.4e-80 271.1 0.1 1.7e-80 270.7 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 EGO20458.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 NIL domain CDC45 PF02724.14 EGO20458.1 - 0.18 10.0 4.0 0.24 9.6 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 EGO20459.1 - 1.6e-63 214.5 0.0 2e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO20459.1 - 1.4e-29 103.2 0.0 2.9e-29 102.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO20459.1 - 0.04 13.2 0.1 0.085 12.2 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGO20459.1 - 0.043 12.7 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGO20459.1 - 0.062 13.2 2.3 0.08 12.8 0.0 2.2 3 1 0 3 3 3 0 Phosphotransferase enzyme family DUF5017 PF16409.5 EGO20459.1 - 0.19 11.2 0.1 2.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5017) fn3_2 PF16893.5 EGO20460.1 - 5.7e-39 132.1 0.9 1.2e-38 131.2 0.9 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EGO20460.1 - 9.4e-27 92.7 0.1 2e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EGO20460.1 - 1.4e-06 28.6 0.0 3.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 EGO20460.1 - 0.0002 21.7 1.6 0.0013 19.1 1.6 2.2 1 1 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.7 EGO20460.1 - 0.00043 20.2 0.1 0.0071 16.3 0.0 2.7 2 1 0 2 2 2 1 twin BRCT domain DUF3006 PF11213.8 EGO20460.1 - 0.0031 17.7 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EGO20460.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EGO20460.1 - 0.039 14.0 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SMN PF06003.12 EGO20461.1 - 9.4 5.4 14.2 12 5.1 14.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Lactamase_B PF00753.27 EGO20462.1 - 1.6e-08 34.8 1.0 3.9e-08 33.5 0.2 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO20462.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Inhibitor_I66 PF16850.5 EGO20465.1 - 3.1e-30 105.0 0.0 3.4e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Retrotrans_gag PF03732.17 EGO20469.1 - 4e-05 23.8 0.2 4e-05 23.8 0.2 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein HABP4_PAI-RBP1 PF04774.15 EGO20469.1 - 0.12 13.2 7.1 0.22 12.4 7.1 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family RVP_2 PF08284.11 EGO20470.1 - 3.4e-06 26.9 0.0 8.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease 14-3-3 PF00244.20 EGO20470.1 - 0.00061 19.4 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 14-3-3 protein gag-asp_proteas PF13975.6 EGO20470.1 - 0.002 18.6 0.0 0.0037 17.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO20470.1 - 0.0036 17.9 0.0 0.0073 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 EGO20472.1 - 0.00025 21.2 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 EGO20473.1 - 0.041 13.7 0.0 0.043 13.6 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease Inhibitor_I66 PF16850.5 EGO20477.1 - 6.5e-41 139.6 0.0 7.2e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Peptidase_M24 PF00557.24 EGO20481.1 - 2e-42 145.3 0.0 2.9e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.9 EGO20482.1 - 1.6e-44 152.1 0.0 5.4e-43 147.1 0.0 2.7 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EGO20482.1 - 4.5e-08 32.3 0.0 8.7e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain TAF4 PF05236.14 EGO20483.1 - 1.5e-35 123.3 4.2 2.2e-35 122.8 4.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Arb1 PF09692.10 EGO20485.1 - 9.9e-08 31.6 0.0 4.3e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PH_4 PF15404.6 EGO20487.1 - 0.09 12.6 0.6 0.15 11.8 0.6 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Plavaka PF18759.1 EGO20488.1 - 1.4e-42 146.1 0.3 1.7e-42 145.9 0.3 1.0 1 0 0 1 1 1 1 Plavaka transposase Rad51 PF08423.11 EGO20492.1 - 0.00099 18.4 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGO20492.1 - 0.0024 17.4 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ABC_tran PF00005.27 EGO20492.1 - 0.086 13.3 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Adeno_IVa2 PF02456.15 EGO20492.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein TcdA_TcdB_pore PF12920.7 EGO20494.1 - 0.061 11.6 0.9 0.07 11.4 0.9 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Ribosomal_L29 PF00831.23 EGO20494.1 - 0.13 12.2 1.8 0.21 11.6 1.8 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein Plavaka PF18759.1 EGO20496.1 - 6.8e-34 117.5 0.6 1.1e-33 116.8 0.1 1.5 2 0 0 2 2 2 1 Plavaka transposase Glyco_hydro_3_C PF01915.22 EGO20497.1 - 1.9e-51 174.9 0.0 3.8e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO20497.1 - 2.2e-32 112.7 0.0 3.5e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO20497.1 - 8.7e-20 70.6 0.0 1.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Oxysterol_BP PF01237.18 EGO20498.1 - 7.5e-115 383.7 0.1 2.4e-114 382.0 0.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EGO20498.1 - 1.2e-17 64.0 0.2 3.7e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EGO20498.1 - 1.3e-06 28.9 0.0 3.4e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 PH domain DNA_ligase_A_M PF01068.21 EGO20499.1 - 5e-54 183.0 0.0 1e-53 182.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGO20499.1 - 1.2e-41 142.9 0.0 2.5e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EGO20499.1 - 2.1e-23 82.5 0.1 4.2e-12 46.3 0.0 2.9 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EGO20499.1 - 1.1e-14 54.8 0.2 1.1e-13 51.6 0.0 2.8 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGO20499.1 - 2.9e-12 47.2 0.0 6.1e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 EGO20499.1 - 3.1e-10 40.3 0.0 6.6e-05 23.2 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGO20499.1 - 0.0013 19.0 0.1 0.71 10.2 0.0 2.7 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EGO20499.1 - 0.0045 16.9 0.1 3.7 7.6 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain BRCT_3 PF18428.1 EGO20499.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF4073 PF13285.6 EGO20499.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Forkhead PF00250.18 EGO20500.1 - 9.2e-26 89.9 0.0 1.6e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Adaptin_N PF01602.20 EGO20501.1 - 3.8e-144 481.1 6.8 4.5e-144 480.9 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGO20501.1 - 1.9e-24 86.1 0.4 5.3e-24 84.7 0.4 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGO20501.1 - 8.7e-09 35.6 7.1 5.7e-07 29.7 0.2 3.8 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO20501.1 - 0.003 17.9 2.6 3.3 8.2 0.1 5.0 4 2 1 5 5 5 1 HEAT repeats HEAT PF02985.22 EGO20501.1 - 0.014 15.6 2.7 72 4.1 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat RICTOR_M PF14666.6 EGO20501.1 - 0.073 12.9 0.6 2.1 8.1 0.0 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain SBF PF01758.16 EGO20502.1 - 6.7e-49 166.2 15.2 1.8e-48 164.9 15.2 1.7 1 0 0 1 1 1 1 Sodium Bile acid symporter family Cation_ATPase_C PF00689.21 EGO20502.1 - 0.00045 20.0 0.3 0.00045 20.0 0.3 3.0 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF4271 PF14093.6 EGO20502.1 - 2.2 8.2 23.6 4.4 7.2 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) adh_short PF00106.25 EGO20503.1 - 1.7e-25 89.6 0.0 3.2e-23 82.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20503.1 - 6e-17 62.0 0.0 3.9e-15 56.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20503.1 - 1.1e-09 38.5 0.3 1.8e-09 37.7 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO20503.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGO20503.1 - 0.059 12.5 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MoCF_biosynth PF00994.24 EGO20503.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 Probable molybdopterin binding domain SF3b1 PF08920.10 EGO20504.1 - 1.6e-23 83.4 2.5 1.6e-23 83.4 2.5 2.2 2 0 0 2 2 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EGO20504.1 - 3.2e-09 37.0 9.5 0.012 16.0 0.1 7.5 4 2 3 8 8 8 2 HEAT repeats HEAT PF02985.22 EGO20504.1 - 3.5e-07 29.9 12.0 0.2 12.0 0.1 9.6 12 0 0 12 12 10 1 HEAT repeat HEAT_EZ PF13513.6 EGO20504.1 - 4.6e-07 30.2 9.0 0.013 16.0 0.0 7.5 9 1 1 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGO20504.1 - 5.7e-07 30.0 1.0 1.1 9.9 0.0 5.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGO20504.1 - 7.2e-07 28.1 1.5 0.035 12.7 0.0 3.4 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 EGO20504.1 - 5.4e-05 23.3 8.5 1.5 8.8 0.0 6.6 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 EGO20504.1 - 6.8e-05 22.6 0.4 1.9 8.1 0.0 4.8 4 1 1 5 5 5 2 NUC173 domain UME PF08064.13 EGO20504.1 - 0.0003 20.7 0.2 0.8 9.6 0.0 4.9 4 3 2 6 6 6 1 UME (NUC010) domain CLASP_N PF12348.8 EGO20504.1 - 0.001 18.7 1.9 1.5 8.3 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal DUF3110 PF11360.8 EGO20504.1 - 0.0058 16.8 0.1 0.021 15.0 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) DUF3385 PF11865.8 EGO20504.1 - 0.0084 16.0 1.1 1.7 8.6 0.1 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Dopey_N PF04118.14 EGO20504.1 - 0.046 12.8 1.3 3.3 6.7 0.0 3.5 4 0 0 4 4 4 0 Dopey, N-terminal MFS_1 PF07690.16 EGO20505.1 - 1.6e-27 96.4 27.8 1.6e-27 96.4 27.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily EAP30 PF04157.16 EGO20506.1 - 4.5e-68 229.0 0.1 5.1e-68 228.9 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Endotoxin_N PF03945.14 EGO20506.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain TPR_12 PF13424.6 EGO20507.1 - 9.7e-07 29.0 0.7 5.7e-05 23.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO20507.1 - 1.6e-05 24.6 0.2 0.096 12.8 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO20507.1 - 2.9e-05 23.7 0.0 0.34 10.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO20507.1 - 7.7e-05 22.6 0.0 0.69 10.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGO20507.1 - 0.0027 18.3 0.0 0.067 13.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO20507.1 - 0.2 11.9 2.7 13 6.1 0.5 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGO20508.1 - 7.6e-10 38.2 0.6 0.011 15.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO20508.1 - 7.8e-09 35.0 0.1 0.00099 19.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO20508.1 - 2.6e-05 24.1 1.8 1 9.8 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO20508.1 - 7.4e-05 23.0 1.4 1.9 8.8 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGO20508.1 - 0.00042 20.8 1.8 0.34 11.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGO20508.1 - 0.0051 16.9 1.2 0.011 15.8 1.2 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 EGO20508.1 - 0.0084 16.9 0.1 0.35 11.8 0.0 3.3 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO20508.1 - 0.016 15.7 0.1 2.3 8.8 0.0 2.7 1 1 1 3 3 3 0 Tetratricopeptide repeat GlutR_N PF05201.15 EGO20508.1 - 0.057 13.2 0.3 0.15 11.9 0.2 1.7 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain RPN7 PF10602.9 EGO20508.1 - 0.064 13.0 3.7 0.22 11.2 0.1 2.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 EGO20508.1 - 0.069 13.2 0.1 1 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 EGO20509.1 - 1.4e-21 77.2 2.7 1.4e-11 44.3 0.0 3.0 3 1 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 EGO20509.1 - 8.6e-07 28.3 0.1 6.9e-05 22.1 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EGO20509.1 - 8.9e-06 24.8 0.2 0.0041 16.0 0.2 2.8 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGO20509.1 - 9.3e-05 21.8 0.2 0.00068 19.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGO20509.1 - 0.00023 20.3 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EGO20509.1 - 0.00092 18.9 2.8 0.0018 18.0 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO20509.1 - 0.001 19.1 0.0 0.001 19.1 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO20509.1 - 0.0032 17.7 0.2 0.0032 17.7 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO20509.1 - 0.0072 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EGO20509.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO20509.1 - 0.049 14.2 2.6 0.074 13.6 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO20509.1 - 0.1 11.3 0.1 0.21 10.3 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EGO20509.1 - 0.1 11.6 0.9 0.22 10.6 0.7 1.6 2 0 0 2 2 2 0 FAD binding domain Sec6 PF06046.13 EGO20510.1 - 1.2e-148 496.0 1.9 3.8e-148 494.4 0.1 2.1 2 1 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EGO20510.1 - 0.0016 17.4 4.8 0.036 13.0 3.9 2.6 1 1 1 2 2 2 1 Vps53-like, N-terminal HECT PF00632.25 EGO20510.1 - 0.0063 16.0 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sec5 PF15469.6 EGO20510.1 - 0.029 14.2 8.1 1.2 9.0 0.0 4.6 3 2 1 4 4 4 0 Exocyst complex component Sec5 Snf7 PF03357.21 EGO20510.1 - 0.32 10.6 9.0 2.1 7.9 9.0 2.4 1 1 0 1 1 1 0 Snf7 CN_hydrolase PF00795.22 EGO20511.1 - 2e-39 135.5 0.0 2.9e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGO20511.1 - 2.6e-23 82.4 0.0 6.2e-23 81.2 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 EGO20511.1 - 0.11 12.2 0.0 0.25 10.9 0.0 1.5 1 1 0 1 1 1 0 Asparagine synthase ACC_central PF08326.12 EGO20512.1 - 3.3e-245 815.8 0.0 4.1e-245 815.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGO20512.1 - 7.7e-173 575.7 0.0 9.8e-173 575.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGO20512.1 - 8e-52 175.8 0.0 1.5e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGO20512.1 - 3.8e-26 91.8 0.0 8.5e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGO20512.1 - 1.2e-20 73.6 0.0 1.8e-19 69.8 0.0 2.9 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGO20512.1 - 1.1e-14 54.0 0.0 2.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EGO20512.1 - 0.001 19.1 0.1 0.0046 17.0 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain DUF4999 PF16390.5 EGO20512.1 - 0.0046 17.2 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function Dala_Dala_lig_C PF07478.13 EGO20512.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGO20512.1 - 0.025 14.1 0.1 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGO20512.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_M20 PF01546.28 EGO20513.1 - 2.5e-27 95.9 0.0 3.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO20513.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO20513.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Dynein_light PF01221.18 EGO20515.1 - 6.3e-37 125.8 0.5 6.9e-37 125.6 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 He_PIG PF05345.12 EGO20516.1 - 6e-09 35.9 7.8 1.8e-06 28.0 0.6 5.5 5 0 0 5 5 5 2 Putative Ig domain CAV_VP3 PF04771.12 EGO20516.1 - 0.054 13.6 1.1 0.22 11.7 1.1 2.0 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein HEAT PF02985.22 EGO20517.1 - 2e-14 52.4 20.0 0.0082 16.3 0.1 9.6 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 EGO20517.1 - 4.9e-14 52.5 12.0 0.023 15.1 0.0 7.9 6 2 3 9 9 9 7 HEAT repeats HEAT_EZ PF13513.6 EGO20517.1 - 2.3e-12 47.1 24.7 0.0025 18.3 0.1 10.0 12 0 0 12 12 11 4 HEAT-like repeat IBN_N PF03810.19 EGO20517.1 - 3.6e-10 39.6 1.5 3.8e-09 36.3 0.2 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 EGO20517.1 - 1.8e-09 37.8 0.3 0.0021 18.1 0.0 4.5 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EGO20517.1 - 6.8e-08 32.0 3.2 0.001 18.3 0.0 4.2 3 2 0 3 3 3 2 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 EGO20517.1 - 1.3e-06 28.3 1.0 0.035 13.8 0.1 4.8 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EGO20517.1 - 7.1e-05 23.3 0.0 0.031 14.9 0.0 4.3 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EGO20517.1 - 0.00021 20.6 3.5 10 5.1 0.0 5.4 5 1 0 6 6 6 2 RNAPII transcription regulator C-terminal Ecm29 PF13001.7 EGO20517.1 - 0.00033 19.5 0.3 2.6 6.6 0.0 5.2 4 1 0 5 5 5 1 Proteasome stabiliser XPC-binding PF09280.11 EGO20517.1 - 0.01 15.6 0.8 0.15 11.9 0.1 3.3 2 0 0 2 2 2 0 XPC-binding domain CLASP_N PF12348.8 EGO20517.1 - 0.015 14.9 0.1 32 4.0 0.0 4.6 4 2 2 6 6 6 0 CLASP N terminal BTB PF00651.31 EGO20518.1 - 1.3e-06 28.5 0.7 6.4e-05 23.2 0.2 2.7 2 1 0 2 2 2 1 BTB/POZ domain DHO_dh PF01180.21 EGO20519.1 - 1.4e-95 319.9 0.0 1.8e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGO20519.1 - 0.022 13.8 0.0 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.19 EGO20520.1 - 8.4e-42 143.3 0.0 8.1e-30 103.7 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGO20520.1 - 2.8e-08 33.3 0.3 4e-06 26.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGO20520.1 - 6.1e-08 32.2 0.0 4e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO20520.1 - 1.8e-06 27.4 0.3 0.0047 16.2 0.0 3.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO20520.1 - 8.4e-05 22.6 0.0 0.00031 20.8 0.0 2.0 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO20520.1 - 0.00053 20.2 0.5 0.0017 18.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO20520.1 - 0.09 12.3 0.3 0.54 9.8 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase MMR_HSR1 PF01926.23 EGO20522.1 - 9.3e-10 38.6 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO20522.1 - 4.5e-08 32.7 0.0 5.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGO20522.1 - 0.00014 22.0 0.4 0.0044 17.1 0.2 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGO20522.1 - 0.0006 19.7 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGO20522.1 - 0.0008 19.9 0.1 0.0013 19.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGO20522.1 - 0.0021 18.5 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 EGO20522.1 - 0.0055 16.9 0.0 0.0093 16.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGO20522.1 - 0.0077 16.3 0.0 0.02 15.0 0.0 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 EGO20522.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.22 EGO20522.1 - 0.015 14.9 0.0 0.076 12.6 0.0 2.0 2 0 0 2 2 2 0 Ras family IstB_IS21 PF01695.17 EGO20522.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EGO20522.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGO20522.1 - 0.094 13.2 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO20522.1 - 0.095 13.0 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO20522.1 - 0.1 12.4 0.3 0.92 9.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGO20522.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_13 PF13166.6 EGO20522.1 - 0.25 9.9 0.1 0.32 9.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain FMO-like PF00743.19 EGO20523.1 - 5.7e-40 137.2 0.0 4.4e-28 98.0 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGO20523.1 - 8e-06 25.2 0.1 0.00051 19.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGO20523.1 - 2.7e-05 23.6 0.9 0.023 14.0 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO20523.1 - 3.5e-05 23.8 0.0 0.00012 22.2 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGO20523.1 - 9.1e-05 21.8 0.0 0.00089 18.6 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO20523.1 - 0.00083 19.5 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Peptidase_C97 PF05903.14 EGO20523.1 - 0.083 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain DAO PF01266.24 EGO20523.1 - 0.15 11.6 0.1 0.15 11.6 0.1 2.6 4 0 0 4 4 4 0 FAD dependent oxidoreductase Ribosomal_L23 PF00276.20 EGO20525.1 - 7.2e-09 35.9 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Metallophos PF00149.28 EGO20526.1 - 4.9e-16 59.8 1.2 2.9e-15 57.3 0.3 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO20526.1 - 5.1e-05 23.5 0.1 0.00062 20.0 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain LRR_8 PF13855.6 EGO20527.1 - 7.2e-14 51.3 14.3 1.2e-09 37.8 6.3 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EGO20527.1 - 2.5e-08 34.1 12.1 7.9e-05 22.9 1.5 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO20527.1 - 0.019 15.4 10.0 0.97 10.2 0.3 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EGO20527.1 - 1.4 9.1 7.6 1.8 8.8 0.6 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DDE_1 PF03184.19 EGO20529.1 - 4.7e-12 45.9 0.0 1e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease BORCS8 PF10167.9 EGO20529.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Med9 PF07544.13 EGO20531.1 - 0.044 13.9 1.2 0.091 12.9 1.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Asp PF00026.23 EGO20532.1 - 5.7e-71 239.5 8.0 7.1e-71 239.2 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO20532.1 - 7.8e-13 49.0 0.2 1.4e-07 31.9 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Terpene_synth_C PF03936.16 EGO20533.1 - 0.00013 21.4 0.7 0.00022 20.7 0.2 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Asp PF00026.23 EGO20534.1 - 9e-58 196.2 0.3 1.1e-57 195.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO20534.1 - 5.8e-12 46.2 1.5 1.2e-07 32.1 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal DHBP_synthase PF00926.19 EGO20535.1 - 5.4e-83 277.2 0.0 6.8e-83 276.9 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.27 EGO20536.1 - 1.5e-31 108.2 8.2 8.9e-18 64.0 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Herp-Cyclin PF09241.10 EGO20539.1 - 0.05 14.2 0.1 0.055 14.1 0.1 1.1 1 0 0 1 1 1 0 Herpesviridae viral cyclin RbsD_FucU PF05025.13 EGO20543.1 - 0.021 15.2 0.5 0.039 14.4 0.5 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family FlxA PF14282.6 EGO20545.1 - 0.03 14.3 0.2 0.045 13.7 0.2 1.3 1 0 0 1 1 1 0 FlxA-like protein WD40 PF00400.32 EGO20546.1 - 8.4e-60 197.3 34.6 4e-09 37.0 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20546.1 - 1.8e-22 79.5 1.5 8.1e-05 22.8 0.1 5.9 4 2 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EGO20546.1 - 1.2e-07 32.1 0.0 2.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 EGO20546.1 - 1.2e-07 31.0 0.0 0.034 13.1 0.0 4.2 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO20546.1 - 6.1e-06 25.2 5.9 0.15 10.7 0.1 4.3 4 2 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO20546.1 - 0.0077 15.0 0.5 0.33 9.6 0.0 3.2 4 0 0 4 4 4 1 Nup133 N terminal like PD40 PF07676.12 EGO20546.1 - 0.024 14.6 0.2 3.8 7.6 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EGO20546.1 - 0.03 13.6 0.2 37 3.5 0.1 3.5 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 EGO20546.1 - 0.083 11.4 0.6 11 4.5 0.2 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain RhoGEF PF00621.20 EGO20548.1 - 9.8e-33 113.9 0.0 1.4e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 EGO20548.1 - 6.7e-19 67.8 8.2 1.1e-18 67.1 8.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGO20548.1 - 3.1 8.1 6.6 6.6 7.0 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_76 PF03663.14 EGO20549.1 - 4.3e-19 69.3 21.2 7.8e-18 65.1 21.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Holin_SPP1 PF04688.13 EGO20549.1 - 0.071 13.3 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 SPP1 phage holin Thymidylate_kin PF02223.17 EGO20550.1 - 2.1e-44 151.4 0.0 2.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EGO20550.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.12 EGO20550.1 - 0.038 13.8 0.1 0.19 11.6 0.0 1.9 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein UQ_con PF00179.26 EGO20551.1 - 2e-18 66.4 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MMR_HSR1 PF01926.23 EGO20552.1 - 4.7e-12 46.0 0.0 7.7e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGO20552.1 - 2.2e-08 34.3 0.3 2.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGO20552.1 - 8.5e-06 25.5 0.1 1.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EGO20552.1 - 3.2e-05 23.9 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EGO20552.1 - 3.7e-05 23.1 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 EGO20552.1 - 8e-05 23.2 0.1 0.00017 22.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 EGO20552.1 - 0.00017 21.7 0.2 0.00039 20.5 0.2 1.5 1 1 0 1 1 1 1 Dynamin family IIGP PF05049.13 EGO20552.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 EGO20552.1 - 0.012 16.1 0.9 0.022 15.2 0.9 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO20552.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO20552.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 EGO20552.1 - 0.035 14.2 0.2 0.062 13.4 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 EGO20552.1 - 0.038 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO20552.1 - 0.04 14.3 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 EGO20552.1 - 0.048 13.2 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EGO20552.1 - 0.063 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_S28 PF05577.12 EGO20553.1 - 1.5e-48 165.7 2.1 1.7e-47 162.2 2.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGO20553.1 - 5.1e-05 22.8 0.1 0.00011 21.8 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family IL4_i_Ig PF18258.1 EGO20553.1 - 1.1 9.5 6.0 33 4.8 0.0 2.7 2 0 0 2 2 2 0 Interleukin-4 inducing immunoglobulin-binding domain UQ_con PF00179.26 EGO20554.1 - 2.4e-16 59.7 0.0 2.6e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGO20554.1 - 0.013 15.8 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EGO20554.1 - 0.05 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain VHS PF00790.19 EGO20555.1 - 4.3e-31 107.7 0.2 8e-31 106.8 0.2 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.6 EGO20555.1 - 4.6e-14 52.0 0.1 1.1e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO20555.1 - 1.3e-13 50.3 0.0 2.7e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO20555.1 - 1.4e-13 50.3 0.1 2.6e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EGO20555.1 - 2.6e-10 40.5 0.8 6.6e-10 39.2 0.8 1.8 1 0 0 1 1 1 1 GAT domain ThiC-associated PF13667.6 EGO20555.1 - 0.049 13.5 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 ThiC-associated domain UNC45-central PF11701.8 EGO20555.1 - 0.072 13.0 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central UIM PF02809.20 EGO20555.1 - 0.28 11.2 5.3 0.053 13.5 0.8 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Pro_isomerase PF00160.21 EGO20556.1 - 1.1e-39 136.2 0.9 2.9e-39 134.9 0.0 2.1 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EGO20556.1 - 0.53 10.7 0.0 0.53 10.7 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4604) MMR_HSR1 PF01926.23 EGO20557.1 - 4.8e-08 33.1 0.0 0.0071 16.4 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase Roc PF08477.13 EGO20557.1 - 0.00042 20.5 0.1 0.024 14.8 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGO20557.1 - 0.00072 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGO20557.1 - 0.0038 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EGO20557.1 - 0.0052 16.3 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGO20557.1 - 0.0085 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 EGO20557.1 - 0.013 14.8 0.0 0.74 9.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 EGO20557.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO20557.1 - 0.054 12.7 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 EGO20557.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 EGO20557.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Y_phosphatase PF00102.27 EGO20557.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ABC_tran PF00005.27 EGO20558.1 - 3.3e-45 154.0 3.3 7.7e-25 88.0 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EGO20558.1 - 2.2e-17 63.8 7.4 2.3e-06 27.7 1.5 4.5 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO20558.1 - 4.1e-13 49.3 2.0 8.6e-05 22.1 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGO20558.1 - 3.6e-09 37.1 0.3 0.0025 18.3 0.0 3.7 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO20558.1 - 1.5e-08 35.0 0.3 0.00025 21.3 0.1 3.4 3 1 0 3 3 2 2 AAA domain ABC_tran_Xtn PF12848.7 EGO20558.1 - 3.1e-08 33.5 3.7 3.1e-08 33.5 3.7 2.5 2 0 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 EGO20558.1 - 9.8e-07 28.9 0.2 0.0074 16.2 0.0 3.1 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EGO20558.1 - 1.1e-06 28.6 0.1 0.011 15.7 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGO20558.1 - 6.1e-06 26.7 0.1 0.086 13.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 EGO20558.1 - 1.8e-05 24.8 0.1 1 9.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 EGO20558.1 - 3.6e-05 23.6 0.2 0.33 10.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGO20558.1 - 3.9e-05 23.3 0.1 0.064 13.0 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EGO20558.1 - 6.7e-05 22.9 0.0 0.14 12.1 0.0 3.0 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 EGO20558.1 - 7.4e-05 23.1 0.1 0.64 10.4 0.0 3.5 3 0 0 3 3 3 2 RNA helicase ATP-synt_ab PF00006.25 EGO20558.1 - 0.00011 21.9 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 EGO20558.1 - 0.00018 21.7 0.3 0.29 11.3 0.1 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGO20558.1 - 0.00036 20.6 0.2 0.042 13.9 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EGO20558.1 - 0.00057 20.2 0.0 0.01 16.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EGO20558.1 - 0.0006 20.0 0.6 2.1 8.6 0.0 3.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EGO20558.1 - 0.00061 20.3 0.1 0.00061 20.3 0.1 4.0 2 1 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EGO20558.1 - 0.0014 17.9 0.0 2.2 7.4 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 EGO20558.1 - 0.0024 17.4 0.1 2.3 7.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 EGO20558.1 - 0.0025 17.6 7.1 0.018 14.7 0.2 3.6 3 1 0 3 3 3 1 AAA ATPase domain DAP3 PF10236.9 EGO20558.1 - 0.0061 15.8 0.1 0.84 8.7 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.9 EGO20558.1 - 0.0074 16.0 0.4 0.6 9.9 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EGO20558.1 - 0.015 15.0 0.2 3.9 7.2 0.0 3.1 4 0 0 4 4 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGO20558.1 - 0.017 14.5 0.0 7.6 5.8 0.0 3.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGO20558.1 - 0.019 14.7 0.1 4.4 7.0 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DLIC PF05783.11 EGO20558.1 - 0.02 13.7 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 EGO20558.1 - 0.021 14.9 3.8 14 5.6 0.0 4.1 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EGO20558.1 - 0.033 13.4 0.0 7.7 5.6 0.0 3.3 3 1 0 3 3 3 0 KAP family P-loop domain AAA_18 PF13238.6 EGO20558.1 - 0.046 14.3 1.6 3.1 8.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EGO20558.1 - 0.046 13.9 0.1 5 7.4 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRPRB PF09439.10 EGO20558.1 - 0.049 13.1 0.1 0.17 11.3 0.0 2.0 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGO20558.1 - 0.053 13.0 5.5 0.14 11.7 0.1 3.6 3 2 2 5 5 4 0 Ferrous iron transport protein B Ras PF00071.22 EGO20558.1 - 0.064 12.8 0.1 16 5.1 0.0 3.3 4 0 0 4 4 3 0 Ras family MobB PF03205.14 EGO20558.1 - 0.09 12.7 1.3 5.6 6.9 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 EGO20558.1 - 0.095 12.3 1.1 3.8 7.1 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 EGO20558.1 - 0.11 12.4 0.1 24 4.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 EGO20558.1 - 0.15 11.5 3.0 0.36 10.3 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family Snurportin1 PF11538.8 EGO20558.1 - 0.87 9.8 4.2 0.26 11.5 0.2 2.3 2 0 0 2 2 1 0 Snurportin1 Dynamin_N PF00350.23 EGO20558.1 - 2.8 8.0 0.0 2.8 8.0 0.0 3.5 5 0 0 5 5 3 0 Dynamin family Tmemb_170 PF10190.9 EGO20559.1 - 6.6e-10 39.3 7.5 3.5e-08 33.8 3.4 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 PS_Dcarbxylase PF02666.15 EGO20560.1 - 6.5e-48 162.9 0.0 9.3e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TRI5 PF06330.11 EGO20564.1 - 0.0014 17.6 0.5 0.0014 17.5 0.5 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 EGO20565.1 - 2.8e-06 26.9 0.4 0.00018 21.0 0.1 2.2 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain TRI5 PF06330.11 EGO20565.1 - 0.007 15.3 0.6 0.014 14.3 0.6 1.5 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) MKT1_C PF12246.8 EGO20569.1 - 4.8e-73 245.3 0.0 5.8e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication zf-C2H2_6 PF13912.6 EGO20570.1 - 0.0013 18.7 0.8 0.0024 17.8 0.1 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 EGO20570.1 - 0.0019 18.5 0.1 0.0046 17.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO20570.1 - 0.045 14.1 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGO20570.1 - 0.17 12.4 0.3 0.17 12.4 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Caskin-Pro-rich PF16907.5 EGO20570.1 - 7.1 7.2 13.7 0.27 11.8 4.4 2.9 2 1 1 3 3 3 0 Proline rich region of Caskin proteins O-FucT PF10250.9 EGO20572.1 - 5e-13 49.5 0.0 7.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aldo_ket_red PF00248.21 EGO20573.1 - 2.6e-46 158.2 0.0 3.2e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.23 EGO20576.1 - 0.0011 19.0 2.8 0.0011 19.0 2.8 1.6 2 0 0 2 2 2 1 Zinc knuckle Acyl-CoA_dh_1 PF00441.24 EGO20577.1 - 2.2e-27 96.1 0.5 3.2e-27 95.6 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EGO20577.1 - 4.7e-17 61.9 0.0 9.2e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EGO20577.1 - 5.3e-15 55.4 0.3 8.5e-15 54.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGO20577.1 - 8e-13 49.0 0.0 4.9e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO20577.1 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Arginosuc_synth PF00764.19 EGO20579.1 - 1.8e-153 511.5 0.0 2.1e-153 511.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGO20579.1 - 5.4e-05 22.8 0.0 8.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGO20579.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_127 PF07944.12 EGO20580.1 - 6e-23 81.1 0.1 7.8e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 ECR1_N PF14382.6 EGO20581.1 - 5.3e-16 58.1 0.1 8.5e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EGO20581.1 - 2e-13 50.5 0.1 3.7e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EGO20581.1 - 0.035 14.7 0.1 0.71 10.5 0.1 2.2 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 zf-MYND PF01753.18 EGO20582.1 - 9e-08 32.1 15.0 2.1e-07 30.9 15.0 1.7 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 EGO20582.1 - 0.033 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.6 EGO20582.1 - 1.2 9.3 10.2 1.3 9.2 7.9 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RRM_1 PF00076.22 EGO20583.1 - 4.8e-15 55.1 0.0 7.6e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO20583.1 - 0.024 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 EGO20583.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3384 PF11864.8 EGO20584.1 - 1.5 7.7 4.3 0.37 9.6 0.3 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) Smr PF01713.21 EGO20585.1 - 2.4e-09 37.4 0.1 6.3e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 EGO20585.1 - 1.6e-05 25.2 5.2 3.5e-05 24.1 5.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Acetyltransf_10 PF13673.7 EGO20586.1 - 2.6e-06 27.4 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO20586.1 - 4e-06 27.1 0.0 8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO20586.1 - 0.0014 19.0 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain O-FucT PF10250.9 EGO20588.1 - 1.9e-08 34.4 0.0 3.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RabGAP-TBC PF00566.18 EGO20589.1 - 1.5e-48 165.3 0.0 2.6e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 EGO20589.1 - 6.3e-06 26.6 0.3 0.0026 18.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGO20589.1 - 6.7e-06 25.6 0.8 0.0029 17.4 0.3 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGO20589.1 - 3e-05 23.3 0.1 0.0022 17.4 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGO20589.1 - 0.00023 21.0 0.5 0.79 9.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair GRAM PF02893.20 EGO20589.1 - 0.001 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain HEPN_Swt1 PF18731.1 EGO20589.1 - 0.046 14.1 0.3 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 Swt1-like HEPN EF-hand_5 PF13202.6 EGO20589.1 - 0.072 12.6 0.0 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF1931 PF09123.11 EGO20589.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) WD40 PF00400.32 EGO20590.1 - 6.1e-54 178.8 23.3 7.8e-10 39.2 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20590.1 - 5.8e-21 74.6 2.0 0.0011 19.2 0.1 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO20590.1 - 5.7e-09 36.1 0.3 0.00024 21.1 0.1 3.9 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGO20590.1 - 2.9e-08 32.8 7.7 0.0038 15.9 0.4 5.2 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO20590.1 - 4e-06 26.0 9.0 0.037 13.0 0.0 4.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 EGO20590.1 - 9.2e-05 22.1 1.1 0.0097 15.5 0.1 2.8 2 2 2 4 4 4 1 Cytolethal distending toxin A/C domain WD40_like PF17005.5 EGO20590.1 - 0.00028 20.3 0.1 0.0085 15.4 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 EGO20590.1 - 0.0027 16.7 3.4 4.6 6.1 0.1 4.1 1 1 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Pectate_lyase22 PF14583.6 EGO20590.1 - 0.0093 14.7 0.1 0.025 13.2 0.0 1.7 1 1 0 1 1 1 1 Oligogalacturonate lyase DUF1513 PF07433.11 EGO20590.1 - 0.016 14.3 0.2 2.6 7.0 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1513) RicinB_lectin_2 PF14200.6 EGO20590.1 - 0.022 15.5 1.0 0.99 10.2 0.0 2.9 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like Cytochrom_D1 PF02239.16 EGO20590.1 - 0.094 11.2 0.0 0.38 9.2 0.0 1.9 2 1 0 2 2 2 0 Cytochrome D1 heme domain MMR_HSR1 PF01926.23 EGO20591.1 - 1.6e-15 57.1 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGO20591.1 - 4.1e-07 30.2 0.0 0.0024 18.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EGO20591.1 - 4.1e-06 26.3 0.0 5.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGO20591.1 - 0.0014 18.6 0.1 0.003 17.5 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 EGO20591.1 - 0.0019 17.5 0.0 0.024 14.0 0.0 2.2 1 1 0 1 1 1 1 Septin AAA_29 PF13555.6 EGO20591.1 - 0.0064 16.2 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 EGO20591.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGO20591.1 - 0.046 13.3 0.0 1.2 8.6 0.0 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGO20591.1 - 0.057 13.7 0.5 4.5 7.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EGO20591.1 - 0.072 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_27 PF13514.6 EGO20591.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGO20591.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF3331 PF11811.8 EGO20594.1 - 0.029 14.2 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) DUF2263 PF10021.9 EGO20595.1 - 3.1e-10 40.6 0.0 5.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Pirin PF02678.16 EGO20596.1 - 4.3e-24 84.6 0.9 7.1e-24 83.9 0.9 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 EGO20596.1 - 4.1e-06 26.9 0.5 0.0082 16.3 0.2 3.6 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 EGO20596.1 - 0.003 17.2 2.7 0.048 13.4 0.7 2.3 2 0 0 2 2 2 1 Cupin domain eRF1_1 PF03463.15 EGO20596.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 1 FAD_oxidored PF12831.7 EGO20597.1 - 0.079 12.3 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aminoglyc_resit PF10706.9 EGO20598.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase RTC4 PF14474.6 EGO20600.1 - 9.4e-26 90.4 0.0 3.2e-25 88.6 0.0 2.0 1 0 0 1 1 1 1 RTC4-like domain zinc_ribbon_16 PF17034.5 EGO20600.1 - 0.087 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon like family PTS_2-RNA PF01885.16 EGO20601.1 - 7.9e-65 218.3 0.0 9.9e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2183 PF09949.9 EGO20602.1 - 1.4e-28 99.1 0.0 4.3e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF5492 PF17596.2 EGO20602.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5492) TPR_2 PF07719.17 EGO20603.1 - 1.1e-07 31.4 0.0 0.022 14.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO20603.1 - 1.6e-05 25.1 0.1 0.0052 17.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO20603.1 - 0.00022 20.9 0.0 0.16 11.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO20603.1 - 0.006 16.4 0.0 0.025 14.4 0.0 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO20603.1 - 0.0073 16.4 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO20603.1 - 0.045 14.3 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGO20603.1 - 0.21 11.7 0.2 14 5.8 0.2 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) zf-Sec23_Sec24 PF04810.15 EGO20604.1 - 0.013 15.5 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Rtf2 PF04641.12 EGO20604.1 - 0.015 14.7 2.3 0.027 13.8 2.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF383 PF04063.14 EGO20605.1 - 2e-60 203.7 0.0 3.8e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGO20605.1 - 2.5e-20 72.0 0.3 4.8e-20 71.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF384) gag-asp_proteas PF13975.6 EGO20608.1 - 0.00013 22.4 0.0 0.0003 21.3 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO20608.1 - 0.0014 19.2 0.0 0.002 18.7 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease AICARFT_IMPCHas PF01808.18 EGO20610.1 - 8.2e-85 284.8 0.0 1e-84 284.5 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGO20610.1 - 5.9e-24 84.1 0.0 1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.6 EGO20611.1 - 5.7e-39 133.7 0.5 7.2e-39 133.4 0.5 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGO20611.1 - 2.5e-08 33.9 0.2 3.9e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGO20611.1 - 6.7e-07 29.6 0.5 1e-06 29.0 0.5 1.3 1 0 0 1 1 1 1 HD domain PARP PF00644.20 EGO20612.1 - 5.4e-14 52.2 1.0 3.7e-09 36.5 0.0 3.2 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain Paired_CXXCH_1 PF09699.10 EGO20612.1 - 0.012 15.3 2.0 0.6 9.9 0.1 3.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) RPAP2_Rtr1 PF04181.13 EGO20612.1 - 0.11 12.8 20.6 2.6 8.4 0.7 5.3 5 1 0 5 5 5 0 Rtr1/RPAP2 family Bac_thur_toxin PF01338.18 EGO20620.1 - 0.15 11.5 2.7 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 Bacillus thuringiensis toxin SirB PF04247.12 EGO20620.1 - 2.1 8.4 12.1 0.7 10.0 2.5 2.7 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB DLH PF01738.18 EGO20622.1 - 5.9e-22 78.3 0.0 6.7e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 EGO20623.1 - 4e-21 75.6 0.0 4.6e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S24 PF00717.23 EGO20624.1 - 2.1e-08 34.0 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGO20624.1 - 7.1e-07 29.1 0.0 0.00019 21.2 0.0 2.7 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 AA_permease PF00324.21 EGO20625.1 - 1.1e-127 426.6 38.8 1.3e-127 426.3 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO20625.1 - 2.4e-38 132.1 42.5 2.9e-38 131.8 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease DDE_1 PF03184.19 EGO20629.1 - 5.6e-33 114.1 0.2 8e-33 113.5 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGO20629.1 - 0.00026 21.0 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Dfp1_Him1_M PF08630.10 EGO20630.1 - 0.11 12.7 0.9 0.15 12.3 0.2 1.6 2 0 0 2 2 2 0 Dfp1/Him1, central region COPI_C PF06957.11 EGO20631.1 - 0.2 10.4 1.5 0.24 10.1 1.5 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus F-box PF00646.33 EGO20633.1 - 0.048 13.6 1.5 0.12 12.3 1.5 1.8 1 0 0 1 1 1 0 F-box domain Hira PF07569.11 EGO20633.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split DDE_1 PF03184.19 EGO20634.1 - 1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease SL4P PF17618.2 EGO20634.1 - 0.021 14.8 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein PUF PF00806.19 EGO20634.1 - 0.15 11.8 0.1 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat FAD_binding_3 PF01494.19 EGO20635.1 - 2.8e-46 158.4 0.1 7.5e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGO20635.1 - 3.9e-06 26.3 0.2 0.00012 21.4 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO20635.1 - 5.4e-05 22.7 0.1 7.5e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EGO20635.1 - 0.00014 21.6 1.7 0.046 13.3 1.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO20635.1 - 0.00016 21.1 0.1 0.00069 19.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGO20635.1 - 0.004 16.2 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 EGO20635.1 - 0.006 15.7 1.5 0.0083 15.2 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGO20635.1 - 0.0066 15.2 0.4 0.52 8.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein ThiF PF00899.21 EGO20635.1 - 0.0066 15.8 0.4 0.014 14.7 0.1 1.6 2 0 0 2 2 2 1 ThiF family NAD_binding_8 PF13450.6 EGO20635.1 - 0.026 14.8 0.5 0.1 12.9 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO20635.1 - 0.044 13.0 0.1 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 EGO20635.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EGO20635.1 - 0.081 12.9 0.4 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Cation_ATPase PF13246.6 EGO20635.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Cation transport ATPase (P-type) GIDA PF01134.22 EGO20635.1 - 0.21 10.6 2.8 1.7 7.7 2.8 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO20635.1 - 0.34 9.7 1.6 11 4.7 0.0 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EGO20635.1 - 0.6 9.1 2.8 4.3 6.3 0.9 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein Na_Ca_ex PF01699.24 EGO20637.1 - 5.7e-12 45.8 23.6 6.7e-09 35.9 8.7 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3995 PF13160.6 EGO20637.1 - 0.081 13.3 2.4 0.11 12.9 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF575 PF04746.12 EGO20637.1 - 0.15 12.3 1.4 0.29 11.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF575) FUN14 PF04930.15 EGO20638.1 - 7.6e-20 71.1 0.6 7.6e-20 71.1 0.6 1.6 2 0 0 2 2 2 1 FUN14 family GerPB PF10803.8 EGO20638.1 - 0.096 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Spore germination GerPB Abhydrolase_3 PF07859.13 EGO20640.1 - 2.1e-22 80.0 0.0 3.4e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO20640.1 - 3.6e-09 36.0 0.0 2.6e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGO20640.1 - 0.01 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGO20640.1 - 0.016 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO20640.1 - 0.13 12.8 1.7 0.18 12.4 1.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Alpha_kinase PF02816.18 EGO20643.1 - 1.7e-06 28.3 0.1 3.5e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family zf-UDP PF14569.6 EGO20643.1 - 0.0075 16.4 0.8 0.026 14.6 0.8 1.9 1 0 0 1 1 1 1 Zinc-binding RING-finger Retro_M PF02813.14 EGO20643.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral M domain Abhydrolase_3 PF07859.13 EGO20645.1 - 1.9e-22 80.2 0.0 3.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO20645.1 - 3.1e-09 36.2 0.0 2.3e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGO20645.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGO20645.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family UPF0029 PF01205.19 EGO20646.1 - 4.5e-26 91.2 0.0 6.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DNA_pol_B PF00136.21 EGO20647.1 - 4.8e-113 378.3 0.0 1.5e-112 376.6 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGO20647.1 - 2.7e-57 193.5 0.0 4.4e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EGO20647.1 - 9.2e-26 90.8 0.0 2.6e-25 89.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EGO20647.1 - 1.7e-16 60.0 7.6 1.7e-16 60.0 7.6 2.9 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal AP3D1 PF06375.11 EGO20647.1 - 0.0072 16.6 2.2 1.8 8.8 0.0 2.8 2 0 0 2 2 2 2 AP-3 complex subunit delta-1 DNA_pol_B_2 PF03175.13 EGO20647.1 - 0.02 13.7 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral NCKAP5 PF15246.6 EGO20647.1 - 0.03 13.9 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein YL1 PF05764.13 EGO20647.1 - 0.22 11.6 7.7 0.52 10.4 7.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Flavin_Reduct PF01613.18 EGO20648.1 - 6.2e-17 62.1 2.8 8.9e-17 61.6 2.8 1.2 1 0 0 1 1 1 1 Flavin reductase like domain zf-DNL PF05180.12 EGO20649.1 - 9.5e-30 102.3 0.1 1.2e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 EGO20649.1 - 1.3 9.0 4.0 11 6.0 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain FAD_binding_3 PF01494.19 EGO20650.1 - 9.3e-45 153.4 0.3 6.5e-44 150.6 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO20650.1 - 1.1e-07 31.4 0.1 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO20650.1 - 4.5e-06 26.3 0.0 6.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EGO20650.1 - 1.4e-05 24.9 0.7 0.012 15.2 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO20650.1 - 3.1e-05 23.4 0.1 0.0027 17.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO20650.1 - 0.00014 20.9 0.4 0.0061 15.5 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 EGO20650.1 - 0.0019 17.0 0.8 0.86 8.2 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein SE PF08491.10 EGO20650.1 - 0.0039 16.3 0.1 0.0078 15.3 0.1 1.5 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EGO20650.1 - 0.0044 16.1 0.9 0.4 9.7 0.0 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein Pyr_redox PF00070.27 EGO20650.1 - 0.0079 16.7 0.7 5 7.8 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO20650.1 - 0.019 14.9 0.8 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.21 EGO20650.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EGO20650.1 - 0.052 13.6 0.0 0.18 11.8 0.0 1.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF4939 PF16297.5 EGO20651.1 - 0.043 13.7 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EGO20652.1 - 6.8e-07 29.1 3.1 1.1e-06 28.4 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO20654.1 - 4.1e-08 33.0 5.9 1e-07 31.7 5.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20654.1 - 0.018 15.0 0.5 0.035 14.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle FAD_binding_3 PF01494.19 EGO20655.1 - 2.8e-45 155.1 0.2 1.5e-44 152.7 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO20655.1 - 5.1e-06 25.9 1.1 0.027 13.7 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO20655.1 - 0.00026 20.3 0.1 0.0099 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO20655.1 - 0.0004 19.9 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO20655.1 - 0.00047 19.1 0.4 0.074 11.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 EGO20655.1 - 0.0048 15.7 0.3 0.29 9.8 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 EGO20655.1 - 0.0099 15.0 0.5 0.017 14.2 0.5 1.4 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EGO20655.1 - 0.0099 15.0 1.0 0.041 12.9 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EGO20655.1 - 0.023 14.3 0.9 0.27 10.8 0.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGO20655.1 - 0.054 13.6 0.0 0.33 11.0 0.0 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGO20655.1 - 0.058 14.0 0.8 6.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO20655.1 - 0.059 13.4 0.6 0.71 9.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.21 EGO20655.1 - 0.066 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 EGO20655.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO20655.1 - 0.13 11.4 0.3 0.22 10.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 EGO20657.1 - 4.8e-33 114.5 30.8 4.8e-33 114.5 30.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Tom22 PF04281.13 EGO20658.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 YGGT PF02325.17 EGO20659.1 - 0.075 13.5 0.5 0.1 13.0 0.5 1.2 1 0 0 1 1 1 0 YGGT family YqbF PF14553.6 EGO20661.1 - 0.0096 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 YqbF, hypothetical protein domain HIT PF01230.23 EGO20662.1 - 4.1e-24 85.2 0.0 6.4e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO20662.1 - 4.2e-08 33.6 0.0 7.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3760 PF12586.8 EGO20663.1 - 0.17 12.1 0.7 0.68 10.2 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) zf-C3HC4_3 PF13920.6 EGO20665.1 - 0.44 10.5 3.2 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HAUS6_N PF14661.6 EGO20666.1 - 1.4e-09 37.8 0.3 2.3e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 6 N-terminus Rootletin PF15035.6 EGO20666.1 - 0.6 10.1 4.5 2.2 8.3 4.5 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Tmemb_170 PF10190.9 EGO20667.1 - 8.1e-07 29.4 5.7 7.5e-06 26.3 4.1 2.1 2 0 0 2 2 2 1 Putative transmembrane protein 170 DDDD PF10161.9 EGO20667.1 - 0.24 11.2 1.5 0.71 9.7 1.5 1.8 1 0 0 1 1 1 0 Putative mitochondrial precursor protein TRIC PF05197.13 EGO20667.1 - 0.84 9.2 5.6 0.35 10.4 0.3 2.1 2 0 0 2 2 2 0 TRIC channel WD40 PF00400.32 EGO20668.1 - 4.4e-117 378.6 53.4 1.5e-09 38.3 0.1 15.2 15 0 0 15 15 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20668.1 - 2.5e-44 149.5 0.2 0.0056 17.0 0.0 13.0 3 3 10 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO20668.1 - 8.4e-28 97.3 4.1 0.21 10.5 0.0 12.1 5 4 4 12 12 12 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO20668.1 - 2e-17 62.6 19.4 3.5 7.7 0.0 12.9 14 0 0 14 14 14 4 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EGO20668.1 - 9.7e-07 27.8 0.4 2.5 6.7 0.0 7.7 8 1 1 9 9 9 1 Nucleoporin Nup120/160 NACHT PF05729.12 EGO20668.1 - 1.1e-06 28.6 0.6 2.7e-05 24.1 0.6 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO20668.1 - 2.1e-05 24.9 0.0 4.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Frtz PF11768.8 EGO20668.1 - 0.00026 19.5 0.0 1.6 7.0 0.0 4.6 5 0 0 5 5 5 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EGO20668.1 - 0.00088 18.7 17.7 20 4.4 0.0 9.6 3 3 6 10 10 10 0 Neuroblastoma-amplified sequence, N terminal Robl_LC7 PF03259.17 EGO20668.1 - 0.0029 17.4 0.2 32 4.4 0.0 5.6 6 0 0 6 6 4 0 Roadblock/LC7 domain Gmad1 PF10647.9 EGO20668.1 - 0.011 15.5 1.6 15 5.2 0.0 5.2 4 1 0 5 5 5 0 Lipoprotein LpqB beta-propeller domain DUF2075 PF09848.9 EGO20668.1 - 0.058 12.6 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGO20668.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGO20668.1 - 0.092 11.9 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EGO20668.1 - 0.16 12.4 0.0 0.69 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 EGO20668.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EGO20668.1 - 0.18 11.0 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Retrotrans_gag PF03732.17 EGO20669.1 - 1.3e-09 38.2 2.1 2.7e-09 37.2 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein NPIP PF06409.11 EGO20670.1 - 0.085 11.9 0.1 0.099 11.7 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) GtrA PF04138.14 EGO20671.1 - 0.036 14.3 1.4 0.06 13.6 1.4 1.4 1 0 0 1 1 1 0 GtrA-like protein RepA_N PF06970.11 EGO20672.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus DUF3251 PF11622.8 EGO20673.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) Agglutinin_C PF18021.1 EGO20674.1 - 4.1e-22 78.5 0.1 1e-12 48.4 0.0 2.5 2 0 0 2 2 2 2 Agglutinin C-terminal Lectin_C_term PF18022.1 EGO20674.1 - 1.6e-16 60.6 0.1 6.1e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin C-terminal domain RicinB_lectin_2 PF14200.6 EGO20674.1 - 1.3e-15 57.8 11.6 7e-10 39.5 2.6 4.4 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like DUF3251 PF11622.8 EGO20677.1 - 0.019 14.6 0.1 0.03 13.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) Agglutinin_C PF18021.1 EGO20678.1 - 1.4e-28 99.2 0.0 2.5e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Agglutinin C-terminal Lectin_C_term PF18022.1 EGO20678.1 - 1.1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain RicinB_lectin_2 PF14200.6 EGO20678.1 - 7.8e-14 52.2 11.0 1.4e-13 51.4 2.1 3.6 3 1 0 4 4 4 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EGO20678.1 - 0.00093 19.4 0.9 0.0019 18.5 0.1 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGO20680.1 - 3e-08 34.3 1.9 2.2e-07 31.5 0.3 2.1 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF1768 PF08719.11 EGO20684.1 - 2.8e-16 60.2 0.0 3.1e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 EGO20685.1 - 0.018 15.3 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) zf-CCHC_3 PF13917.6 EGO20688.1 - 1.6e-06 28.0 1.2 3e-06 27.1 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO20688.1 - 1.1e-05 25.2 5.1 1.7e-05 24.7 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO20688.1 - 0.048 13.2 0.8 0.09 12.3 0.8 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain Cerato-platanin PF07249.12 EGO20689.1 - 0.00057 20.0 0.0 0.0007 19.7 0.0 1.1 1 0 0 1 1 1 1 Cerato-platanin DUF3251 PF11622.8 EGO20690.1 - 0.011 15.4 0.1 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) NCD2 PF04905.13 EGO20691.1 - 0.0062 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) PARP PF00644.20 EGO20693.1 - 6.7e-14 51.9 3.8 4.3e-11 42.8 3.8 3.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RPAP2_Rtr1 PF04181.13 EGO20693.1 - 3.4 8.1 12.9 2.6 8.4 0.5 3.1 3 0 0 3 3 3 0 Rtr1/RPAP2 family PARP PF00644.20 EGO20694.1 - 1.5e-20 73.6 4.8 6.2e-09 35.7 0.0 4.1 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 EGO20696.1 - 6.7e-13 48.7 5.6 6.9e-10 38.8 0.5 3.9 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 EGO20697.1 - 1.2e-08 34.8 0.7 4e-06 26.6 0.1 3.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DHQS PF01959.16 EGO20697.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase II RPAP2_Rtr1 PF04181.13 EGO20697.1 - 0.57 10.5 12.1 8.1 6.8 0.9 3.5 2 1 1 3 3 3 0 Rtr1/RPAP2 family Fer4_11 PF13247.6 EGO20697.1 - 6.1 7.0 16.8 4.2 7.5 1.0 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain PARP PF00644.20 EGO20698.1 - 1.1e-13 51.3 0.0 1.3e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PLATZ PF04640.14 EGO20698.1 - 2.3 8.9 5.7 0.32 11.6 1.2 1.9 2 0 0 2 2 2 0 PLATZ transcription factor PARP PF00644.20 EGO20699.1 - 1.5e-12 47.5 0.7 1.4e-09 37.8 0.0 3.1 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain YacG PF03884.14 EGO20699.1 - 1.1 9.0 40.2 0.27 11.0 6.2 5.0 5 0 0 5 5 5 0 DNA gyrase inhibitor YacG PARP PF00644.20 EGO20700.1 - 1.4e-11 44.4 1.1 7.5e-09 35.5 1.1 2.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 EGO20701.1 - 7.1e-31 107.6 0.0 9.8e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Alpha_kinase PF02816.18 EGO20702.1 - 8e-18 65.2 0.0 9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.16 EGO20704.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1768 PF08719.11 EGO20705.1 - 6.8e-62 208.5 0.0 9.1e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1768) Sigma_reg_C PF13791.6 EGO20705.1 - 0.014 15.6 0.0 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Pox_E8 PF03394.13 EGO20705.1 - 0.029 13.9 0.0 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus E8 protein DUF3196 PF11428.8 EGO20705.1 - 0.1 12.1 0.8 3.9 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3196) FAM167 PF11652.8 EGO20705.1 - 0.23 11.9 1.5 15 6.2 0.1 2.5 2 0 0 2 2 2 0 FAM167 Complex1_LYR PF05347.15 EGO20705.1 - 0.6 10.2 4.0 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Complex 1 protein (LYR family) PARP PF00644.20 EGO20706.1 - 7.9e-09 35.4 0.1 5e-07 29.5 0.1 3.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain YyzF PF14116.6 EGO20706.1 - 0.47 10.5 9.1 12 6.0 0.4 3.6 3 0 0 3 3 3 0 YyzF-like protein Fer4_11 PF13247.6 EGO20706.1 - 0.86 9.8 15.3 0.65 10.1 0.9 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain RPAP2_Rtr1 PF04181.13 EGO20706.1 - 5.8 7.3 13.1 28 5.1 1.2 3.7 2 1 1 3 3 3 0 Rtr1/RPAP2 family APH PF01636.23 EGO20707.1 - 2.1e-05 24.6 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGO20707.1 - 3.2e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20707.1 - 0.00085 19.0 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGO20707.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.11 EGO20707.1 - 0.045 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 EGO20707.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PARP PF00644.20 EGO20711.1 - 4.1e-08 33.1 1.0 1.8e-07 30.9 1.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain YyzF PF14116.6 EGO20711.1 - 0.1 12.6 0.4 0.1 12.6 0.4 4.0 5 0 0 5 5 5 0 YyzF-like protein YacG PF03884.14 EGO20711.1 - 1.6 8.5 16.4 0.74 9.6 5.2 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG PLATZ PF04640.14 EGO20712.1 - 0.65 10.7 16.7 0.49 11.1 3.8 3.6 3 1 0 3 3 3 0 PLATZ transcription factor zf-MYND PF01753.18 EGO20712.1 - 0.77 9.9 22.0 3.4 7.8 1.8 4.4 3 1 0 3 3 3 0 MYND finger RPAP2_Rtr1 PF04181.13 EGO20712.1 - 3.2 8.1 17.5 0.5 10.7 4.1 4.0 3 1 0 3 3 3 0 Rtr1/RPAP2 family DUF1768 PF08719.11 EGO20713.1 - 7.3e-30 104.3 0.0 1.1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 EGO20714.1 - 3.8e-28 98.7 0.0 5.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) zf-UBR PF02207.20 EGO20714.1 - 0.94 9.7 23.0 8.5 6.6 5.4 3.2 1 1 2 3 3 3 0 Putative zinc finger in N-recognin (UBR box) WD40 PF00400.32 EGO20716.1 - 2.1e-11 44.2 5.7 0.0012 19.6 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20716.1 - 1.8e-05 24.9 0.1 0.6 10.4 0.0 4.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PX PF00787.24 EGO20717.1 - 3.9e-13 49.4 0.0 8.5e-13 48.3 0.0 1.5 2 0 0 2 2 2 1 PX domain Abhydrolase_1 PF00561.20 EGO20718.1 - 6.6e-13 48.9 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EGO20718.1 - 1.5e-08 34.7 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein NADH_dhqG_C PF09326.11 EGO20719.1 - 0.076 13.7 0.2 0.21 12.3 0.2 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal AIM3 PF17096.5 EGO20719.1 - 3.8 8.5 6.5 4 8.5 1.1 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF3578 PF12102.8 EGO20720.1 - 0.029 14.0 0.3 0.037 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) G-alpha PF00503.20 EGO20721.1 - 7.7e-52 176.6 0.9 8.9e-52 176.4 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Lipocalin_7 PF14651.6 EGO20721.1 - 0.098 12.6 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Ribosomal_L37e PF01907.19 EGO20726.1 - 6.2e-27 93.5 14.0 1.1e-26 92.7 14.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EGO20726.1 - 0.005 16.8 1.6 0.0077 16.2 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 EGO20726.1 - 0.015 15.3 0.8 0.02 15.0 0.7 1.4 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 EGO20726.1 - 0.054 13.5 0.8 0.079 13.0 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4 PF00097.25 EGO20726.1 - 0.6 10.0 5.5 0.96 9.4 5.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO20726.1 - 0.61 10.0 5.5 5.9 6.8 6.6 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 EGO20726.1 - 0.7 9.7 4.2 13 5.7 1.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GATA PF00320.27 EGO20727.1 - 5.7e-18 64.2 3.4 7.4e-18 63.9 3.4 1.2 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGO20727.1 - 0.0057 16.1 1.5 0.0092 15.5 1.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 EGO20727.1 - 0.014 15.4 0.4 0.015 15.4 0.4 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DZR PF12773.7 EGO20727.1 - 0.059 13.4 0.5 0.18 11.8 0.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGO20727.1 - 0.067 13.3 0.0 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EGO20727.1 - 0.094 12.2 3.1 5.2 6.6 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EGO20727.1 - 0.11 12.7 0.6 0.16 12.2 0.6 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rubredoxin_2 PF18073.1 EGO20727.1 - 0.15 11.8 1.3 9.6 6.0 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain SUIM_assoc PF16619.5 EGO20728.1 - 0.00032 20.7 5.3 0.0067 16.5 6.1 2.3 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ATP11 PF06644.11 EGO20728.1 - 0.084 12.6 0.4 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 ATP11 protein TFIIA PF03153.13 EGO20728.1 - 0.087 12.8 9.1 0.11 12.5 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 EGO20729.1 - 2.1e-11 43.6 8.9 2.1e-05 24.7 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO20729.1 - 1.2e-07 31.8 2.5 1.2e-07 31.8 2.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO20729.1 - 5.9e-06 26.7 8.3 0.017 15.9 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGO20729.1 - 0.002 17.9 4.4 0.54 10.1 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain Fer2 PF00111.27 EGO20729.1 - 0.0071 16.3 0.4 0.013 15.5 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-RAG1 PF10426.9 EGO20729.1 - 0.036 14.2 0.5 0.036 14.2 0.5 2.0 2 1 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_aberr PF17017.5 EGO20729.1 - 0.081 13.1 6.0 1.2 9.2 5.3 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger Opi1 PF08618.10 EGO20730.1 - 2.7e-120 402.5 17.2 1.2e-88 298.2 11.4 3.0 3 1 1 4 4 4 2 Transcription factor Opi1 Perilipin PF03036.16 EGO20730.1 - 1.5e-05 24.2 0.1 5e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Perilipin family REF PF05755.12 EGO20730.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) p450 PF00067.22 EGO20731.1 - 2.9e-44 151.6 0.0 4e-44 151.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EGO20733.1 - 1.2e-15 57.7 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO20733.1 - 1.4e-13 51.3 0.0 2.7e-13 50.4 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO20733.1 - 2.7e-10 40.7 0.0 4.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO20733.1 - 1.7e-09 37.7 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGO20733.1 - 2.6e-07 30.3 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 EGO20733.1 - 1.3e-06 29.1 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO20733.1 - 9.7e-06 25.1 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGO20733.1 - 0.0007 19.1 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGO20733.1 - 0.003 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TrkA_N PF02254.18 EGO20733.1 - 0.0053 17.0 0.0 0.0084 16.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain UPF0146 PF03686.13 EGO20733.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) TPMT PF05724.11 EGO20733.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 EGO20733.1 - 0.034 14.1 0.1 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 EGO20733.1 - 0.051 12.5 0.0 0.073 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) NodS PF05401.11 EGO20733.1 - 0.053 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) UDPG_MGDP_dh_N PF03721.14 EGO20733.1 - 0.061 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CheR PF01739.18 EGO20733.1 - 0.14 11.6 0.0 16 4.9 0.0 2.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 EGO20734.1 - 5e-15 55.7 0.0 7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO20734.1 - 9.5e-14 51.9 0.0 2.7e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO20734.1 - 3.9e-11 43.4 0.0 6.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO20734.1 - 4.7e-09 36.2 0.0 1.2e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO20734.1 - 1.3e-07 32.3 0.0 2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGO20734.1 - 1.7e-06 27.6 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 EGO20734.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGO20734.1 - 0.00055 19.4 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGO20734.1 - 0.0029 17.2 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 EGO20734.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FmrO PF07091.11 EGO20734.1 - 0.16 11.5 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF898 PF05987.13 EGO20735.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) GATA PF00320.27 EGO20738.1 - 4.2e-08 32.7 7.9 9.5e-08 31.5 7.9 1.6 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 EGO20738.1 - 0.13 12.4 0.9 0.24 11.5 0.9 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf FAD_binding_3 PF01494.19 EGO20740.1 - 1.2e-10 41.1 0.2 7.8e-10 38.5 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EGO20741.1 - 2.1e-13 50.3 3.1 0.00017 20.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 EGO20741.1 - 1.3e-08 34.5 1.1 3.6e-07 29.7 1.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO20741.1 - 1.5e-08 34.2 0.5 6.3e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGO20741.1 - 2.5e-07 30.6 3.9 0.0022 17.6 0.5 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO20741.1 - 5.2e-07 28.7 0.0 0.00035 19.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EGO20741.1 - 1.9e-05 24.8 0.2 0.00012 22.3 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO20741.1 - 0.00029 21.3 1.0 0.01 16.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO20741.1 - 0.00066 19.0 2.2 0.0042 16.4 0.3 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO20741.1 - 0.0007 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGO20741.1 - 0.0026 17.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EGO20741.1 - 0.0051 15.9 0.1 0.44 9.5 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EGO20741.1 - 0.015 14.4 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO20741.1 - 0.069 12.0 0.4 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EGO20741.1 - 0.12 11.6 0.1 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Thiolase_N PF00108.23 EGO20742.1 - 7.5e-77 258.2 3.6 1.1e-76 257.7 1.2 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO20742.1 - 1.2e-45 154.1 0.7 1.2e-45 154.1 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO20742.1 - 5.8e-05 22.8 0.5 0.005 16.5 0.1 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGO20742.1 - 0.015 15.2 0.3 5.3 7.0 0.0 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SIR2 PF02146.17 EGO20743.1 - 1.4e-47 161.9 0.0 5.7e-46 156.7 0.0 2.6 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EGO20743.1 - 1e-06 28.6 1.1 2.5e-05 24.1 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EGO20743.1 - 0.099 12.4 0.1 7.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Histone PF00125.24 EGO20744.1 - 1.2e-49 168.0 3.8 1.3e-49 167.9 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGO20744.1 - 2.7e-05 24.5 0.1 4.2e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGO20744.1 - 5.9e-05 23.2 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EGO20744.1 - 0.00023 21.8 2.5 0.00029 21.4 2.5 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGO20744.1 - 0.00072 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGO20744.1 - 0.09 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 EGO20745.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGO20745.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGO20745.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO20745.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO20745.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGO20745.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Nucleopor_Nup85 PF07575.13 EGO20746.1 - 5.6e-62 210.1 0.0 8.3e-60 202.9 0.0 2.0 1 1 0 1 1 1 1 Nup85 Nucleoporin RhoGAP PF00620.27 EGO20748.1 - 7.8e-47 158.9 0.0 1.7e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGO20748.1 - 1.8e-14 53.8 1.5 1.4e-13 50.9 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF745 PF05335.13 EGO20748.1 - 0.013 15.2 3.5 0.023 14.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) RFC1 PF08519.12 EGO20748.1 - 0.065 13.4 0.4 0.53 10.4 0.0 2.4 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain Baculo_PEP_C PF04513.12 EGO20748.1 - 0.093 12.8 0.3 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGO20748.1 - 0.1 12.6 1.8 1.4 9.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EGO20748.1 - 0.22 11.7 3.5 0.81 9.9 3.5 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EGO20748.1 - 0.6 9.6 3.8 1.1 8.8 3.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 EGO20748.1 - 0.79 8.3 3.6 1.3 7.6 3.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 EGO20748.1 - 1 9.4 11.2 0.64 10.1 8.8 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TBCA PF02970.16 EGO20748.1 - 1.5 9.2 7.0 5.3 7.4 7.0 1.9 1 1 0 1 1 1 0 Tubulin binding cofactor A F-box-like PF12937.7 EGO20749.1 - 3e-09 36.6 2.3 1.4e-08 34.5 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EGO20749.1 - 0.086 12.7 0.4 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 F-box F-box PF00646.33 EGO20749.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.8 3 0 0 3 3 3 0 F-box domain LRR_6 PF13516.6 EGO20749.1 - 0.17 12.0 1.6 12 6.3 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat CENP-T_C PF15511.6 EGO20750.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGO20750.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGO20750.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO20750.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO20750.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGO20750.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGO20751.1 - 1.2e-49 168.0 3.8 1.3e-49 167.9 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGO20751.1 - 2.7e-05 24.5 0.1 4.2e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGO20751.1 - 5.9e-05 23.2 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EGO20751.1 - 0.00023 21.8 2.5 0.00029 21.4 2.5 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGO20751.1 - 0.00072 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGO20751.1 - 0.09 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Asp PF00026.23 EGO20752.1 - 1.7e-69 234.7 3.4 2.1e-69 234.4 3.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO20752.1 - 5.1e-10 39.9 1.9 4e-05 23.9 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Methyltransf_16 PF10294.9 EGO20753.1 - 5.8e-20 71.7 0.0 1.2e-19 70.7 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGO20753.1 - 0.00053 19.9 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EGO20753.1 - 0.0039 16.3 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TCL1_MTCP1 PF01840.17 EGO20753.1 - 0.037 13.7 0.3 0.099 12.3 0.1 1.8 2 0 0 2 2 2 0 TCL1/MTCP1 family PCMT PF01135.19 EGO20753.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EGO20754.1 - 6.4e-26 91.1 0.0 9.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGO20754.1 - 0.00022 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rhomboid PF01694.22 EGO20755.1 - 1.6e-18 67.2 14.5 5.6e-18 65.4 14.5 1.9 1 1 0 1 1 1 1 Rhomboid family Pkinase PF00069.25 EGO20756.1 - 0.00042 19.7 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20756.1 - 0.00064 19.4 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGO20756.1 - 0.025 14.5 0.2 0.15 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-CCHC PF00098.23 EGO20758.1 - 2.3e-08 33.8 3.0 4.4e-08 32.8 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO20758.1 - 5.2e-06 26.7 5.7 7.1e-06 26.2 3.4 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 EGO20758.1 - 0.25 11.1 0.9 0.45 10.3 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20758.1 - 3.3 7.8 7.5 0.87 9.6 3.1 2.2 2 0 0 2 2 2 0 Zinc knuckle PYC_OADA PF02436.18 EGO20759.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Conserved carboxylase domain DUF4939 PF16297.5 EGO20760.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) SspO PF08175.12 EGO20760.1 - 0.27 11.7 1.7 0.59 10.6 1.7 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein O family p47_phox_C PF08944.11 EGO20763.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain zf-CCHC PF00098.23 EGO20765.1 - 0.00023 21.1 5.3 0.00023 21.1 5.3 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20765.1 - 0.0012 18.7 4.2 0.0012 18.7 4.2 1.7 2 0 0 2 2 2 1 Zinc knuckle Copper-fist PF00649.18 EGO20765.1 - 0.019 14.4 0.8 0.035 13.6 0.8 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain Retrotrans_gag PF03732.17 EGO20766.1 - 1.7e-09 37.8 1.4 4.9e-09 36.4 0.2 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20766.1 - 3.7e-08 33.1 5.7 7.4e-08 32.1 5.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20766.1 - 5.1 7.1 9.5 0.22 11.5 3.3 1.9 2 0 0 2 2 2 0 Zinc knuckle Calpain_inhib PF00748.19 EGO20767.1 - 0.11 13.0 0.4 0.24 11.9 0.4 1.5 1 0 0 1 1 1 0 Calpain inhibitor Nnf1 PF03980.14 EGO20768.1 - 8.3e-15 55.1 0.7 1.6e-14 54.2 0.7 1.4 1 0 0 1 1 1 1 Nnf1 DUF4521 PF15021.6 EGO20768.1 - 0.021 14.8 0.2 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) CENP-Q PF13094.6 EGO20768.1 - 0.023 14.9 2.2 0.12 12.6 2.4 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PI-TkoII_IV PF18714.1 EGO20768.1 - 0.069 12.6 0.1 0.091 12.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Prominin PF05478.11 EGO20768.1 - 0.19 9.7 0.3 0.23 9.4 0.3 1.1 1 0 0 1 1 1 0 Prominin GrpE PF01025.19 EGO20768.1 - 0.27 10.9 4.9 0.75 9.4 4.9 1.7 1 1 0 1 1 1 0 GrpE DUF2921 PF11145.8 EGO20769.1 - 0.0079 14.1 0.3 0.012 13.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-RING_2 PF13639.6 EGO20769.1 - 0.011 16.0 1.9 0.011 16.0 1.9 3.0 2 1 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 EGO20769.1 - 0.013 15.2 1.0 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 EGO20769.1 - 0.023 14.9 5.5 0.049 13.9 2.7 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGO20769.1 - 0.21 11.5 8.7 0.29 11.0 1.9 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO20769.1 - 0.47 10.3 5.3 0.82 9.6 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO20769.1 - 1.8 8.5 3.9 27 4.7 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 EGO20771.1 - 4.2e-14 52.5 0.0 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20771.1 - 9.1e-09 35.2 0.0 8.7e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EGO20771.1 - 0.0049 16.3 0.0 0.0061 16.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO20771.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4541 PF15074.6 EGO20772.1 - 0.05 14.2 0.5 0.11 13.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) zf-CCHC_4 PF14392.6 EGO20773.1 - 0.038 13.7 1.6 0.073 12.8 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle adh_short PF00106.25 EGO20774.1 - 1.1e-11 44.5 0.0 1.8e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20774.1 - 8e-11 41.9 0.0 3e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20774.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NFACT-C PF11923.8 EGO20776.1 - 0.025 14.5 0.0 0.027 14.4 0.0 1.0 1 0 0 1 1 1 0 NFACT protein C-terminal domain YL1 PF05764.13 EGO20778.1 - 6.4e-06 26.5 7.6 1e-05 25.8 7.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein zf-CCHC PF00098.23 EGO20778.1 - 0.0033 17.4 2.0 0.0074 16.3 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 EGO20778.1 - 0.051 13.2 14.7 0.11 12.1 14.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGO20778.1 - 0.19 11.0 14.1 0.32 10.3 14.1 1.4 1 0 0 1 1 1 0 BUD22 EMC3_TMCO1 PF01956.16 EGO20778.1 - 0.25 11.1 0.8 0.49 10.1 0.8 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-CCHC_5 PF14787.6 EGO20778.1 - 0.31 10.8 0.1 0.31 10.8 0.1 1.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CDC45 PF02724.14 EGO20778.1 - 0.47 8.7 13.0 0.69 8.1 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 EGO20778.1 - 1.8 6.8 10.8 3 6.1 10.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mit_KHE1 PF10173.9 EGO20778.1 - 2.5 8.1 7.0 0.98 9.5 3.6 2.0 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related Presenilin PF01080.17 EGO20778.1 - 3 6.5 4.1 4.2 6.0 4.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4939 PF16297.5 EGO20779.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Peptidase_S30 PF01577.16 EGO20781.1 - 0.0027 17.4 0.7 0.019 14.6 0.0 2.4 3 0 0 3 3 3 1 Potyvirus P1 protease zf-AD PF07776.15 EGO20781.1 - 4.6 7.6 7.1 2.5 8.4 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger associated domain (zf-AD) Pkinase PF00069.25 EGO20783.1 - 0.00037 19.9 0.0 0.00037 19.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20783.1 - 0.0066 16.1 0.0 0.0067 16.0 0.0 1.0 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGO20783.1 - 0.025 14.5 0.1 0.028 14.4 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO20783.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Rhomboid PF01694.22 EGO20784.1 - 2e-10 40.9 3.6 2.2e-10 40.8 3.6 1.0 1 0 0 1 1 1 1 Rhomboid family Retrotrans_gag PF03732.17 EGO20786.1 - 1.7e-05 25.0 0.6 4.7e-05 23.6 0.6 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20786.1 - 0.00019 21.3 3.6 0.00041 20.3 3.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 EGO20786.1 - 0.064 13.9 0.3 0.55 10.9 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease Retrotrans_gag PF03732.17 EGO20787.1 - 2.3e-06 27.8 1.2 3.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4042 PF13251.6 EGO20790.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Pkinase PF00069.25 EGO20791.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20791.1 - 0.0037 16.9 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Retrotrans_gag PF03732.17 EGO20793.1 - 0.0027 18.0 0.1 0.0027 18.0 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20793.1 - 0.24 11.6 0.3 0.24 11.6 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle AAA_35 PF14516.6 EGO20794.1 - 0.072 11.9 0.0 0.15 10.9 0.0 1.4 1 1 1 2 2 2 0 AAA-like domain gag-asp_proteas PF13975.6 EGO20795.1 - 0.00019 21.9 0.0 0.00045 20.7 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO20795.1 - 0.0006 20.4 0.0 0.00072 20.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO20795.1 - 0.011 15.4 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Siva PF05458.12 EGO20795.1 - 0.06 13.0 0.0 0.071 12.8 0.0 1.3 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Retrotrans_gag PF03732.17 EGO20796.1 - 7.3e-08 32.6 0.1 2.1e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Nnf1 PF03980.14 EGO20799.1 - 8.3e-15 55.1 0.7 1.6e-14 54.2 0.7 1.4 1 0 0 1 1 1 1 Nnf1 DUF4521 PF15021.6 EGO20799.1 - 0.021 14.8 0.2 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) CENP-Q PF13094.6 EGO20799.1 - 0.023 14.9 2.2 0.12 12.6 2.4 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PI-TkoII_IV PF18714.1 EGO20799.1 - 0.069 12.6 0.1 0.091 12.2 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Prominin PF05478.11 EGO20799.1 - 0.19 9.7 0.3 0.23 9.4 0.3 1.1 1 0 0 1 1 1 0 Prominin GrpE PF01025.19 EGO20799.1 - 0.27 10.9 4.9 0.75 9.4 4.9 1.7 1 1 0 1 1 1 0 GrpE DUF2921 PF11145.8 EGO20800.1 - 0.0074 14.2 0.2 0.011 13.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-RING_2 PF13639.6 EGO20800.1 - 0.011 16.0 1.9 0.011 16.0 1.9 3.0 2 1 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 EGO20800.1 - 0.013 15.2 1.0 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 EGO20800.1 - 0.023 14.9 5.5 0.049 13.9 2.7 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain YfzA PF14118.6 EGO20800.1 - 0.058 13.8 0.2 0.21 12.0 0.2 1.9 1 0 0 1 1 1 0 YfzA-like protein zf-C3HC4_2 PF13923.6 EGO20800.1 - 0.21 11.5 8.7 0.29 11.0 1.9 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO20800.1 - 0.47 10.3 5.3 0.82 9.6 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO20800.1 - 1.8 8.5 3.9 27 4.7 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 EGO20802.1 - 8.5e-14 51.5 0.0 4.8e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20802.1 - 2.9e-09 36.8 0.0 3.2e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EGO20802.1 - 0.0017 17.8 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO20802.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transposase_21 PF02992.14 EGO20804.1 - 4.3e-05 22.9 0.1 7.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Pkinase PF00069.25 EGO20806.1 - 0.00037 19.9 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20806.1 - 0.00064 19.4 0.0 0.00086 18.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGO20806.1 - 0.024 14.5 0.2 0.15 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Retrotrans_gag PF03732.17 EGO20807.1 - 5.4e-06 26.6 0.7 1.1e-05 25.7 0.7 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein Pkinase PF00069.25 EGO20811.1 - 0.00053 19.4 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20811.1 - 0.013 15.1 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGO20811.1 - 0.039 13.9 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Retrotran_gag_2 PF14223.6 EGO20812.1 - 5.1e-13 48.9 0.3 6.8e-13 48.5 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type adh_short PF00106.25 EGO20814.1 - 8.7e-28 97.1 0.0 3.2e-24 85.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO20814.1 - 1e-19 71.0 0.0 6.2e-16 58.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO20814.1 - 3.1e-08 33.8 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO20814.1 - 1.1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO20814.1 - 2e-06 27.4 0.0 9.5e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase zf-rbx1 PF12678.7 EGO20817.1 - 7.9e-09 35.7 2.4 1.7e-08 34.6 2.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO20817.1 - 7.6e-08 32.6 8.4 8.7e-07 29.2 8.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO20817.1 - 2.3e-06 27.3 8.1 3.5e-06 26.7 2.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO20817.1 - 7.9e-06 25.7 2.8 1.5e-05 24.8 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO20817.1 - 5.6e-05 23.0 2.2 0.00011 22.1 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGO20817.1 - 0.00012 21.7 7.6 0.0013 18.4 0.5 2.8 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGO20817.1 - 0.00018 21.3 1.1 0.00018 21.3 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO20817.1 - 0.0007 19.6 0.4 0.0026 17.7 0.4 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGO20817.1 - 0.0015 18.5 0.5 0.0038 17.3 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGO20817.1 - 0.002 17.9 3.7 0.0048 16.7 3.8 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGO20817.1 - 0.0076 15.9 1.2 0.018 14.7 1.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2921 PF11145.8 EGO20817.1 - 0.01 13.8 0.2 0.015 13.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 EGO20817.1 - 0.11 12.5 1.5 0.27 11.3 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger zf-P11 PF03854.14 EGO20817.1 - 0.24 11.1 2.9 0.54 10.0 2.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 EGO20817.1 - 1.9 8.4 4.7 0.46 10.3 1.1 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EGO20817.1 - 5.9 7.1 8.7 0.36 11.0 3.2 1.7 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 EGO20817.1 - 7.7 6.8 7.0 55 4.0 7.0 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Nnf1 PF03980.14 EGO20818.1 - 3.9e-15 56.2 0.7 7.4e-15 55.3 0.7 1.4 1 0 0 1 1 1 1 Nnf1 CENP-Q PF13094.6 EGO20818.1 - 0.015 15.5 3.5 0.089 13.0 4.0 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 EGO20818.1 - 0.035 14.5 2.4 0.067 13.6 2.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Kre28 PF17097.5 EGO20818.1 - 0.057 12.4 2.4 0.094 11.7 2.4 1.3 1 0 0 1 1 1 0 Spindle pole body component PI-TkoII_IV PF18714.1 EGO20818.1 - 0.096 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV YabA PF06156.13 EGO20818.1 - 0.1 13.2 0.3 0.22 12.2 0.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA GrpE PF01025.19 EGO20818.1 - 0.37 10.4 4.0 0.91 9.2 4.0 1.7 1 1 0 1 1 1 0 GrpE TFIIA PF03153.13 EGO20819.1 - 7.3 6.5 19.1 5 7.0 15.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Retrotrans_gag PF03732.17 EGO20820.1 - 1.5e-08 34.8 0.3 1.5e-08 34.8 0.3 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20820.1 - 4.1e-08 32.9 5.7 8e-08 32.0 5.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20820.1 - 0.063 13.3 2.9 0.18 11.8 2.9 1.7 1 0 0 1 1 1 0 Zinc knuckle MULE PF10551.9 EGO20822.1 - 8.4e-05 22.9 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Peptidase_S30 PF01577.16 EGO20822.1 - 0.0026 17.4 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 Potyvirus P1 protease Pkinase PF00069.25 EGO20823.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO20823.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Retrotrans_gag PF03732.17 EGO20824.1 - 4.5e-05 23.7 4.3 0.00018 21.7 1.4 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20824.1 - 8.9e-05 22.4 2.2 0.00015 21.6 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle KASH_CCD PF14662.6 EGO20824.1 - 1 9.1 5.9 0.11 12.3 1.0 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Retrotrans_gag PF03732.17 EGO20825.1 - 4.7e-05 23.6 0.3 4.7e-05 23.6 0.3 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20825.1 - 0.18 12.0 1.3 1 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 EGO20826.1 - 1.3e-05 25.6 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO20826.1 - 4.6e-05 24.0 0.0 6.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO20826.1 - 0.0026 17.5 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.6 EGO20828.1 - 4.4e-06 27.0 0.0 3.5e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGO20828.1 - 6.2e-05 23.9 0.0 8.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Plavaka PF18759.1 EGO20830.1 - 3.7e-10 39.5 0.1 1.2e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase Nnf1 PF03980.14 EGO20832.1 - 5.5e-15 55.7 0.7 1e-14 54.8 0.7 1.4 1 0 0 1 1 1 1 Nnf1 CENP-Q PF13094.6 EGO20832.1 - 0.01 16.1 3.1 0.089 13.0 4.0 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ZapB PF06005.12 EGO20832.1 - 0.036 14.5 2.4 0.067 13.6 2.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Kre28 PF17097.5 EGO20832.1 - 0.058 12.3 2.4 0.094 11.7 2.4 1.3 1 0 0 1 1 1 0 Spindle pole body component PI-TkoII_IV PF18714.1 EGO20832.1 - 0.093 12.2 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV GrpE PF01025.19 EGO20832.1 - 0.37 10.4 4.0 0.91 9.2 4.0 1.7 1 1 0 1 1 1 0 GrpE DUF3270 PF11674.8 EGO20833.1 - 0.047 13.9 0.1 0.047 13.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Retrotran_gag_2 PF14223.6 EGO20835.1 - 5.8e-12 45.5 0.2 1.3e-05 24.9 0.0 2.1 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type Peptidase_S30 PF01577.16 EGO20838.1 - 0.075 12.6 0.8 0.33 10.5 0.0 2.3 3 0 0 3 3 3 0 Potyvirus P1 protease RIO1 PF01163.22 EGO20839.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGO20839.1 - 0.011 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Rhomboid PF01694.22 EGO20840.1 - 0.00074 19.5 2.6 0.0011 18.9 2.5 1.4 1 1 0 1 1 1 1 Rhomboid family DUF421 PF04239.12 EGO20841.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Retrotrans_gag PF03732.17 EGO20847.1 - 1.5e-05 25.2 1.1 5.7e-05 23.3 1.1 2.1 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20847.1 - 0.00014 21.8 6.3 0.00039 20.4 6.3 1.8 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 EGO20848.1 - 8.9e-09 35.1 0.6 1.4e-08 34.4 0.5 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.17 EGO20849.1 - 6.6e-08 32.7 0.8 2.7e-07 30.8 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO20849.1 - 2.4e-07 30.5 5.0 5e-07 29.5 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO20849.1 - 0.022 14.7 2.4 0.022 14.7 2.4 2.0 2 0 0 2 2 2 0 Zinc knuckle Integrase_H2C2 PF17921.1 EGO20850.1 - 5.6e-16 58.4 3.1 8.4e-16 57.8 3.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 EGO20850.1 - 5.1 7.0 8.6 0.48 10.3 3.8 1.7 2 0 0 2 2 2 0 GAG-pre-integrase domain MLVIN_C PF18697.1 EGO20851.1 - 0.07 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF2839 PF10999.8 EGO20853.1 - 0.26 11.7 1.9 0.38 11.2 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2839) zf-CCHC_4 PF14392.6 EGO20854.1 - 0.043 13.6 1.6 0.073 12.8 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Pol_alpha_B_N PF08418.10 EGO20854.1 - 0.099 12.6 1.8 0.12 12.3 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RIO1 PF01163.22 EGO20855.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EGO20855.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF4939 PF16297.5 EGO20856.1 - 0.074 12.9 0.0 0.074 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) zf-CCHC_3 PF13917.6 EGO20857.1 - 0.36 10.8 6.4 0.81 9.7 6.4 1.6 1 0 0 1 1 1 0 Zinc knuckle CRF PF00473.17 EGO20860.1 - 0.22 11.6 0.3 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF1082 PF06449.11 EGO20861.1 - 0.15 12.0 0.2 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) PDH PF02153.17 EGO20863.1 - 5.1e-13 48.6 0.0 6.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EGO20863.1 - 4.1e-05 23.8 0.0 7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGO20863.1 - 0.00019 21.9 0.0 0.0005 20.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGO20863.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGO20863.1 - 0.088 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EGO20863.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ArgJ PF01960.18 EGO20864.1 - 2.1e-148 494.1 1.9 2.4e-148 493.9 1.9 1.0 1 0 0 1 1 1 1 ArgJ family Ribosomal_L35Ae PF01247.18 EGO20865.1 - 4e-45 151.9 0.3 4.5e-45 151.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGO20865.1 - 0.0012 19.0 0.0 0.98 9.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 EGO20865.1 - 0.094 12.5 0.7 1.1 9.1 0.3 2.4 2 1 1 3 3 3 0 Putative transposon-encoded protein (DUF2080) adh_short_C2 PF13561.6 EGO20866.1 - 1.5e-55 188.3 0.1 3.6e-54 183.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO20866.1 - 4.5e-40 137.2 2.8 9.8e-39 132.8 2.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO20866.1 - 6.1e-11 42.6 0.1 1.1e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO20866.1 - 0.015 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Maf PF02545.14 EGO20867.1 - 4.9e-34 117.6 0.0 6.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein WD40 PF00400.32 EGO20868.1 - 2.5e-14 53.4 3.1 0.00022 22.0 0.1 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO20868.1 - 3.8e-07 30.3 0.1 0.062 13.6 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO20868.1 - 0.018 14.9 0.3 0.28 11.1 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Exo_endo_phos PF03372.23 EGO20871.1 - 6.8e-12 45.4 0.2 1.9e-11 43.9 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EGO20871.1 - 2.2e-08 34.0 3.2 1.6e-05 24.9 0.4 2.5 2 0 0 2 2 2 2 GRF zinc finger MCPVI PF02993.14 EGO20871.1 - 0.75 9.6 5.1 1.6 8.5 5.1 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Kinesin PF00225.23 EGO20872.1 - 1.4e-103 346.3 2.1 1.4e-103 346.3 2.1 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGO20872.1 - 6.6e-62 207.9 0.1 1.1e-61 207.2 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding Cast PF10174.9 EGO20872.1 - 0.002 16.5 7.8 0.002 16.5 7.8 1.7 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone KxDL PF10241.9 EGO20872.1 - 0.048 13.9 2.2 4.1 7.8 0.4 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 EGO20872.1 - 0.049 13.7 4.3 0.28 11.2 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 EGO20872.1 - 0.054 13.3 6.1 0.13 12.1 6.1 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 EGO20872.1 - 0.054 11.0 5.0 0.075 10.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PRKG1_interact PF15898.5 EGO20872.1 - 0.068 14.1 8.4 0.072 14.0 6.1 2.3 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain HVSL PF09749.9 EGO20872.1 - 0.07 12.6 0.8 0.14 11.6 0.8 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein ERM PF00769.19 EGO20872.1 - 0.071 12.9 6.7 0.17 11.7 6.7 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATPase_2 PF01637.18 EGO20872.1 - 0.073 13.0 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGO20872.1 - 0.11 11.8 0.6 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin CC2-LZ PF16516.5 EGO20872.1 - 0.11 12.8 3.2 0.84 10.0 0.3 2.9 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF5042 PF16445.5 EGO20872.1 - 0.14 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) LPP PF04728.13 EGO20872.1 - 0.16 12.3 3.0 0.43 11.0 0.7 2.9 3 0 0 3 3 2 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 EGO20872.1 - 0.2 11.7 9.0 0.17 12.0 7.1 1.9 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EGO20872.1 - 0.2 10.5 6.5 2.1 7.1 6.6 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EGO20872.1 - 0.25 11.5 7.1 1 9.5 7.1 2.0 1 1 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.12 EGO20872.1 - 0.29 11.6 4.8 13 6.4 0.7 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 EGO20872.1 - 0.29 10.6 12.7 0.64 9.5 12.7 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.20 EGO20872.1 - 0.32 10.3 5.2 0.5 9.7 4.6 1.7 1 1 0 1 1 1 0 Tropomyosin YabA PF06156.13 EGO20872.1 - 0.48 11.1 10.6 7 7.3 0.1 4.2 4 1 0 4 4 3 0 Initiation control protein YabA DUF4201 PF13870.6 EGO20872.1 - 0.55 10.0 6.0 1.5 8.5 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 EGO20872.1 - 0.57 9.5 4.0 0.25 10.7 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.6 EGO20872.1 - 0.59 9.4 5.1 1.1 8.5 1.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4686 PF15742.5 EGO20872.1 - 0.72 8.9 11.2 2.1 7.4 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) FlxA PF14282.6 EGO20872.1 - 0.76 9.8 10.7 0.92 9.5 6.8 2.9 2 1 1 3 3 3 0 FlxA-like protein DUF724 PF05266.14 EGO20872.1 - 0.89 9.3 3.9 3.3 7.5 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 EGO20872.1 - 0.94 8.7 7.2 1 8.6 5.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 EGO20872.1 - 1.4 9.0 10.9 1.1 9.4 0.3 3.5 2 1 1 3 3 3 0 TolA binding protein trimerisation Fez1 PF06818.15 EGO20872.1 - 1.5 9.2 8.2 0.15 12.5 2.6 2.1 2 1 0 2 2 2 0 Fez1 Atg14 PF10186.9 EGO20872.1 - 2.5 7.1 11.0 0.24 10.4 5.3 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 EGO20872.1 - 2.8 8.6 9.2 0.48 11.1 1.7 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 EGO20872.1 - 5.1 7.2 6.6 14 5.9 3.3 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 EGO20872.1 - 5.2 7.2 11.1 1.6 8.8 4.4 2.8 2 1 1 3 3 2 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 EGO20872.1 - 5.6 7.0 8.9 2.1 8.4 5.8 1.9 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EGO20872.1 - 7.2 6.7 11.6 73 3.4 11.6 2.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DAP3 PF10236.9 EGO20873.1 - 1.5e-68 231.3 0.0 2e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EGO20873.1 - 2e-09 38.1 0.0 3.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGO20873.1 - 0.002 17.7 0.2 0.0046 16.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO20873.1 - 0.004 17.4 0.0 0.15 12.3 0.0 2.9 1 1 0 2 2 2 1 AAA domain DUF5074 PF16819.5 EGO20873.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) ATPase_2 PF01637.18 EGO20873.1 - 0.019 14.9 0.0 0.06 13.2 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EGO20873.1 - 0.048 13.4 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EGO20873.1 - 0.048 13.4 0.2 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 EGO20873.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGO20873.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RHSP PF07999.11 EGO20873.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein GATA PF00320.27 EGO20875.1 - 5.6e-14 51.5 2.9 1.1e-13 50.5 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger GRA6 PF05084.13 EGO20875.1 - 3.9 7.4 9.6 10 6.0 9.6 1.7 1 1 0 1 1 1 0 Granule antigen protein (GRA6) Sds3 PF08598.11 EGO20876.1 - 2.3e-06 27.8 0.1 3.5e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Sds3-like Gemini_AL1_M PF08283.11 EGO20879.1 - 2.7e-40 136.7 1.2 7.7e-40 135.3 1.2 1.8 1 0 0 1 1 1 1 Geminivirus rep protein central domain Gemini_AL1 PF00799.20 EGO20879.1 - 2.7e-11 43.8 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain TniB PF05621.11 EGO20879.1 - 0.035 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EGO20879.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.23 EGO20880.1 - 1.7e-09 37.5 0.2 3.8e-09 36.4 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGO20880.1 - 0.045 13.6 0.0 0.57 10.0 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4939 PF16297.5 EGO20882.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 EGO20882.1 - 0.1 12.9 0.1 0.18 12.1 0.0 1.5 2 0 0 2 2 2 0 Retrotransposon gag protein gag-asp_proteas PF13975.6 EGO20883.1 - 0.0049 17.4 0.0 0.0055 17.2 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO20883.1 - 0.024 14.4 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO20883.1 - 0.042 14.5 0.0 0.047 14.3 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 EGO20884.1 - 5e-07 29.5 2.0 9.7e-07 28.6 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO20884.1 - 0.00046 20.4 5.9 0.00069 19.8 2.9 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein Utp21 PF04192.12 EGO20885.1 - 7.1e-66 222.0 0.4 1.1e-65 221.4 0.4 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EGO20885.1 - 1.5e-15 57.2 0.0 0.0028 17.9 0.0 6.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO20885.1 - 2.4e-15 56.6 19.4 0.017 15.9 0.0 10.1 10 0 0 10 10 10 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGO20885.1 - 0.00063 18.6 0.6 0.089 11.5 0.1 3.6 3 1 1 4 4 4 1 Nup133 N terminal like Nup160 PF11715.8 EGO20885.1 - 0.041 12.5 0.2 3.5 6.2 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Utp12 PF04003.12 EGO20885.1 - 0.044 14.1 0.2 0.09 13.1 0.2 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family Cytochrom_D1 PF02239.16 EGO20885.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Sfi1 PF08457.10 EGO20886.1 - 4.2e-31 108.1 101.9 1.1e-21 77.0 57.1 4.5 1 1 2 3 3 3 3 Sfi1 spindle body protein DUF4578 PF15147.6 EGO20886.1 - 0.072 14.0 7.0 0.19 12.6 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4578) PIG-Y PF15159.6 EGO20887.1 - 1.8e-19 70.4 7.0 2e-19 70.3 7.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PSI_PsaF PF02507.15 EGO20887.1 - 0.069 13.0 0.2 0.075 12.9 0.2 1.1 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Adenylsucc_synt PF00709.21 EGO20889.1 - 0.0039 16.2 0.0 0.0045 16.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase APG6_N PF17675.1 EGO20889.1 - 0.012 16.1 0.5 0.015 15.8 0.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region XRCC4 PF06632.12 EGO20889.1 - 0.022 13.6 0.1 0.025 13.4 0.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Rx_N PF18052.1 EGO20889.1 - 0.023 14.9 2.3 0.036 14.3 2.3 1.2 1 0 0 1 1 1 0 Rx N-terminal domain UPF0242 PF06785.11 EGO20889.1 - 0.033 14.3 0.6 0.037 14.1 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 EGO20889.1 - 0.036 14.3 4.3 0.059 13.6 4.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 EGO20889.1 - 0.058 13.6 0.7 0.093 13.0 0.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Matrilin_ccoil PF10393.9 EGO20889.1 - 0.12 12.3 1.1 0.2 11.5 1.1 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin MCU PF04678.13 EGO20889.1 - 0.13 12.4 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SlyX PF04102.12 EGO20889.1 - 9 7.0 7.5 0.4 11.3 1.1 1.9 2 0 0 2 2 2 0 SlyX ox_reductase_C PF08635.10 EGO20890.1 - 2.5e-71 237.9 0.2 3.7e-71 237.3 0.2 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EGO20890.1 - 4.9e-24 85.4 0.1 1.3e-23 84.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO20890.1 - 0.0036 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EGO20891.1 - 4.1e-18 66.3 0.1 6.9e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-C2HE PF16278.5 EGO20892.1 - 2.3e-18 66.4 0.3 5.3e-18 65.2 0.3 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EGO20892.1 - 3.9e-14 53.1 0.0 9.1e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGO20892.1 - 4.6e-11 43.3 0.0 9.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 HIT domain zf-C2H2_2 PF12756.7 EGO20892.1 - 0.032 14.6 1.3 0.081 13.3 0.9 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prp19 PF08606.11 EGO20892.1 - 0.077 13.0 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like Ribosomal_S21e PF01249.18 EGO20893.1 - 1.8e-39 133.7 0.1 2e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e RabGAP-TBC PF00566.18 EGO20894.1 - 1.3e-43 149.1 6.2 1.3e-41 142.6 6.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EGO20894.1 - 2.9e-07 30.1 0.0 8.5e-06 25.3 0.0 2.3 1 1 1 2 2 2 1 Rab-binding domain (RBD) PPP4R2 PF09184.11 EGO20896.1 - 5.5e-22 78.7 0.1 6.2e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 PPP4R2 SUI1 PF01253.22 EGO20897.1 - 1.1e-28 99.5 0.3 1.4e-28 99.2 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 SNRNP27 PF08648.12 EGO20898.1 - 4.4e-25 87.5 4.7 8.5e-25 86.6 4.7 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RRM_1 PF00076.22 EGO20900.1 - 4.1e-11 42.5 0.0 1.1e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 EGO20901.1 - 2.9e-44 150.7 0.1 8.9e-44 149.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO20901.1 - 3.4e-09 36.5 0.1 2.2e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGO20901.1 - 1.9e-08 34.4 0.1 6e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO20901.1 - 3.7e-08 33.9 0.2 3.1e-05 24.4 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EGO20901.1 - 8.9e-08 32.4 0.2 3.1e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGO20901.1 - 3.8e-06 26.3 0.0 8.1e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGO20901.1 - 0.00017 22.1 0.1 0.0026 18.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGO20901.1 - 0.00024 21.4 0.8 0.0011 19.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EGO20901.1 - 0.00032 21.0 3.6 0.013 15.7 0.1 3.1 3 1 1 4 4 2 1 AAA domain AAA_14 PF13173.6 EGO20901.1 - 0.00053 20.0 0.0 0.0022 18.0 0.0 2.0 3 0 0 3 3 2 1 AAA domain CENP-F_leu_zip PF10473.9 EGO20901.1 - 0.00054 20.0 0.3 0.00096 19.2 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RuvB_N PF05496.12 EGO20901.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGO20901.1 - 0.00084 19.3 0.5 0.012 15.6 0.0 2.5 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 EGO20901.1 - 0.00086 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 EGO20901.1 - 0.0017 18.7 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EGO20901.1 - 0.0019 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 EGO20901.1 - 0.0026 17.5 0.4 0.0068 16.1 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO20901.1 - 0.0031 17.0 0.1 0.027 14.0 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EGO20901.1 - 0.0037 17.2 1.1 0.015 15.2 0.0 2.5 4 0 0 4 4 2 1 NTPase AAA_33 PF13671.6 EGO20901.1 - 0.0038 17.4 0.0 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGO20901.1 - 0.0044 16.8 0.2 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 EGO20901.1 - 0.0077 15.7 0.0 0.58 9.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EGO20901.1 - 0.0088 15.4 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGO20901.1 - 0.013 15.5 0.1 0.087 12.7 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 EGO20901.1 - 0.014 15.0 0.6 0.054 13.1 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 EGO20901.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGO20901.1 - 0.019 14.7 0.1 0.037 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO20901.1 - 0.043 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGO20901.1 - 0.047 13.5 0.2 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGO20901.1 - 0.061 13.2 1.3 0.73 9.7 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 EGO20901.1 - 0.069 12.0 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EGO20901.1 - 0.087 12.5 0.3 1 9.0 0.0 2.7 3 1 0 3 3 2 0 Sigma-54 interaction domain ATPase PF06745.13 EGO20901.1 - 0.097 12.0 0.6 0.5 9.7 0.0 2.3 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.18 EGO20901.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein DnaB_C PF03796.15 EGO20901.1 - 0.13 11.6 1.0 9.3 5.5 0.1 2.7 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain Parvo_NS1 PF01057.17 EGO20901.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 P5CR_dimer PF14748.6 EGO20902.1 - 4.3e-38 129.7 1.8 4.3e-38 129.7 1.8 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGO20902.1 - 9.4e-15 55.0 0.2 6.4e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGO20902.1 - 0.013 15.2 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 EGO20902.1 - 0.079 11.9 0.1 0.25 10.3 0.1 1.7 2 0 0 2 2 2 0 Prephenate dehydrogenase Methyltransf_11 PF08241.12 EGO20903.1 - 3.6e-06 27.5 0.0 6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO20903.1 - 8.5e-06 26.4 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO20903.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO20903.1 - 0.018 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGO20903.1 - 0.12 13.1 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAC PF01849.18 EGO20904.1 - 3.2e-20 71.9 0.0 5.3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 EGO20904.1 - 0.042 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF1264 PF06884.11 EGO20905.1 - 3.6e-71 238.3 0.3 7.5e-71 237.2 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1264) LAM_C PF12544.8 EGO20905.1 - 0.078 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Lysine-2,3-aminomutase DUF1727 PF08353.10 EGO20906.1 - 0.02 14.8 0.7 0.048 13.6 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Spc7 PF08317.11 EGO20906.1 - 0.11 11.3 29.3 0.54 9.1 6.5 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 EGO20906.1 - 4.9 7.6 34.0 8.9 6.7 21.5 2.9 1 1 1 2 2 2 0 Fez1 HSP90 PF00183.18 EGO20907.1 - 1.3e-232 773.3 24.6 1.6e-232 773.0 24.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGO20907.1 - 2.4e-13 50.5 0.0 4.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGO20907.1 - 6.8e-09 35.7 0.1 1.9e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAP_alpha PF03896.16 EGO20907.1 - 0.2 10.8 6.3 0.44 9.7 6.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cofac_haem_bdg PF04187.13 EGO20907.1 - 0.22 11.5 1.6 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C37 PF05416.12 EGO20907.1 - 0.75 8.2 8.3 0.38 9.2 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Aminotran_5 PF00266.19 EGO20908.1 - 1.3e-37 129.6 0.0 1.6e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TRAPPC10 PF12584.8 EGO20910.1 - 7.5e-34 116.7 0.0 1.7e-32 112.3 0.0 2.5 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 EGO20910.1 - 0.024 14.6 0.0 0.098 12.7 0.0 2.0 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking ALG3 PF05208.13 EGO20913.1 - 4.9e-141 470.3 8.7 5.8e-141 470.1 8.7 1.0 1 0 0 1 1 1 1 ALG3 protein Lyase_1 PF00206.20 EGO20914.1 - 1.1e-97 327.3 0.0 1.4e-97 326.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EGO20914.1 - 3.1e-25 88.7 0.1 7.1e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal YabA PF06156.13 EGO20916.1 - 0.014 16.0 0.8 0.044 14.4 0.8 1.8 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 EGO20916.1 - 0.022 14.8 1.6 0.022 14.8 1.6 2.0 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 EGO20916.1 - 0.03 14.1 2.1 0.11 12.2 2.1 2.0 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 EGO20916.1 - 0.068 13.6 5.9 0.057 13.9 2.6 2.3 1 1 1 2 2 2 0 Cell division protein ZapB KASH_CCD PF14662.6 EGO20916.1 - 0.083 12.7 4.5 0.11 12.3 3.0 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 EGO20916.1 - 0.21 11.5 2.2 0.69 9.8 2.2 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 EGO20916.1 - 0.25 11.6 3.4 0.3 11.3 1.8 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper eIF-3c_N PF05470.12 EGO20916.1 - 1.1 7.5 6.2 9.9 4.3 5.9 2.1 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus K-box PF01486.17 EGO20916.1 - 2.3 8.4 6.5 0.31 11.2 1.8 2.0 2 0 0 2 2 2 0 K-box region PIG-H PF10181.9 EGO20918.1 - 4.1e-16 58.6 0.0 6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component RabGAP-TBC PF00566.18 EGO20919.1 - 7.1e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 EGO20921.1 - 3.2e-09 36.2 5.6 3.9e-09 35.9 5.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EGO20921.1 - 6.9e-08 32.3 0.3 9.1e-08 31.9 0.3 1.1 1 0 0 1 1 1 1 Nodulin-like MFS_1_like PF12832.7 EGO20921.1 - 0.005 15.8 2.7 0.0063 15.4 0.4 1.8 2 0 0 2 2 2 1 MFS_1 like family ABC2_membrane PF01061.24 EGO20921.1 - 0.24 10.8 9.7 0.065 12.6 6.6 1.7 2 0 0 2 2 2 0 ABC-2 type transporter DUF2304 PF10066.9 EGO20921.1 - 1.4 9.2 4.8 0.56 10.5 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DIOX_N PF14226.6 EGO20922.1 - 9.2e-29 100.6 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO20922.1 - 3.2e-18 66.1 0.0 5.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Far-17a_AIG1 PF04750.14 EGO20923.1 - 2.5e-17 62.8 1.2 2.7e-17 62.8 1.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Syntaxin PF00804.25 EGO20924.1 - 4.6e-33 114.6 9.7 6.7e-33 114.1 9.7 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EGO20924.1 - 4.5e-09 36.2 0.2 1.5e-08 34.5 0.2 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EGO20924.1 - 1.7e-08 34.8 11.8 2.2e-08 34.4 8.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein DUF5383 PF17355.2 EGO20924.1 - 0.006 17.0 0.1 0.017 15.5 0.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5383) VitD-bind_III PF09164.10 EGO20924.1 - 0.019 15.0 0.3 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Tweety PF04906.13 EGO20924.1 - 0.033 12.9 4.3 0.13 10.9 0.3 2.3 2 0 0 2 2 2 0 Tweety BLOC1_2 PF10046.9 EGO20924.1 - 0.067 13.5 5.8 8.3 6.8 0.1 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4988 PF16378.5 EGO20924.1 - 0.079 12.6 3.2 2.9 7.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function Spectrin PF00435.21 EGO20924.1 - 0.082 13.4 7.2 0.3 11.6 0.5 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF4064 PF13273.6 EGO20924.1 - 0.13 12.6 1.7 0.13 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DASH_Dam1 PF08653.10 EGO20924.1 - 0.21 11.4 2.1 0.39 10.5 0.2 2.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 EGO20924.1 - 0.36 11.3 2.8 37 4.9 0.4 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 EGO20924.1 - 0.46 11.0 8.3 1.4 9.4 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF2939 PF11159.8 EGO20924.1 - 0.85 10.1 5.5 0.57 10.6 2.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2939) FUSC PF04632.12 EGO20924.1 - 1.7 7.0 4.3 1.4 7.4 2.4 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family Prominin PF05478.11 EGO20924.1 - 3.4 5.5 8.8 0.77 7.6 0.2 2.3 2 1 0 2 2 2 0 Prominin Synaptobrevin PF00957.21 EGO20924.1 - 7.4 6.4 13.5 14 5.6 6.1 3.2 2 2 0 2 2 2 0 Synaptobrevin PIN_8 PF18476.1 EGO20924.1 - 8.4 6.2 9.8 3.8 7.3 2.5 2.4 1 1 1 2 2 2 0 PIN like domain DUF4094 PF13334.6 EGO20924.1 - 8.5 6.9 7.6 16 6.0 0.0 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF4094) CdvA PF18822.1 EGO20924.1 - 8.9 6.2 11.3 1.2 8.9 0.6 3.7 3 1 1 4 4 4 0 CdvA-like coiled-coil domain Cas1_AcylT PF07779.12 EGO20925.1 - 9.4e-141 470.0 13.3 1.2e-140 469.6 13.3 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 EGO20925.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4731 PF15875.5 EGO20925.1 - 0.072 13.3 0.1 0.33 11.2 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) zf-AN1 PF01428.16 EGO20926.1 - 1e-10 41.6 4.0 1e-10 41.6 4.0 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Aminotran_1_2 PF00155.21 EGO20927.1 - 1.3e-84 284.4 0.0 1.5e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.22 EGO20928.1 - 3.5e-13 48.6 10.3 0.0058 16.8 0.1 8.3 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EGO20928.1 - 4.2e-09 36.7 9.6 0.0093 16.3 0.1 6.1 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 EGO20928.1 - 0.0032 17.5 0.0 21 5.1 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO20928.1 - 0.019 14.5 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 EGO20928.1 - 0.025 15.1 9.2 1.3 9.6 0.1 5.7 5 1 1 6 6 6 0 HEAT-like repeat Tom37 PF10568.9 EGO20930.1 - 3.7e-30 104.8 0.0 6.6e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGO20930.1 - 7.6e-12 44.9 0.3 2.1e-11 43.4 0.3 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGO20930.1 - 4.2e-06 27.4 0.0 1.3e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EGO20930.1 - 6.5e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO20930.1 - 0.082 13.1 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO20930.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.31 EGO20932.1 - 2.7e-06 26.8 0.9 3.4e-06 26.5 0.9 1.1 1 0 0 1 1 1 1 Ion transport protein ECF_trnsprt PF12822.7 EGO20933.1 - 0.02 15.0 9.2 0.17 12.0 5.6 2.1 2 0 0 2 2 2 0 ECF transporter, substrate-specific component TMEM247 PF15444.6 EGO20933.1 - 3.2 7.7 3.7 8.2 6.4 3.7 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Methyltr_RsmB-F PF01189.17 EGO20936.1 - 4e-77 258.4 0.0 5.6e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGO20936.1 - 1.4e-08 35.1 0.0 1e-07 32.4 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EGO20936.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EGO20936.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EGO20936.1 - 0.038 13.7 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 EGO20936.1 - 0.086 13.6 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGO20936.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MMM1 PF10296.9 EGO20938.1 - 6e-33 114.3 0.1 7.3e-16 58.1 0.0 3.0 1 1 2 3 3 3 3 Maintenance of mitochondrial morphology protein 1 Aminotran_5 PF00266.19 EGO20939.1 - 5e-14 52.0 0.0 7.2e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO20939.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FAD_binding_3 PF01494.19 EGO20940.1 - 5.8e-15 55.4 0.0 8.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EGO20940.1 - 0.014 14.4 0.0 0.15 11.1 0.0 2.2 2 1 0 2 2 2 0 Squalene epoxidase AT_hook PF02178.19 EGO20941.1 - 5.8e-06 25.6 52.5 0.037 13.9 6.3 4.5 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.13 EGO20942.1 - 6.1e-13 49.6 0.6 1.2e-12 48.6 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGO20942.1 - 0.00045 19.9 0.1 0.0013 18.4 0.1 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pkinase PF00069.25 EGO20946.1 - 6.6e-47 160.1 0.0 8.2e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO20946.1 - 2.1e-27 96.0 0.0 2.7e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO20946.1 - 0.0029 17.6 0.1 0.013 15.4 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO20946.1 - 0.011 15.1 0.0 0.032 13.5 0.0 1.7 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EGO20946.1 - 0.014 15.1 0.0 0.33 10.5 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGO20946.1 - 0.024 13.6 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DEAD PF00270.29 EGO20948.1 - 1.6e-45 155.0 0.0 5.4e-45 153.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO20948.1 - 1.2e-28 99.7 0.0 3.7e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO20948.1 - 0.00032 20.7 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 EGO20948.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD EF_assoc_2 PF08356.12 EGO20949.1 - 0.00052 20.0 0.1 0.00079 19.4 0.1 1.2 1 0 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.6 EGO20949.1 - 0.0018 18.7 0.4 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF_assoc_1 PF08355.12 EGO20949.1 - 0.0061 16.1 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 EF hand associated EF-hand_8 PF13833.6 EGO20949.1 - 0.038 13.8 0.2 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair Methyltransf_16 PF10294.9 EGO20950.1 - 3.4e-18 66.0 0.0 9.6e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EGO20950.1 - 9.8e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0146 PF03686.13 EGO20950.1 - 0.0063 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) PrmA PF06325.13 EGO20950.1 - 0.0065 15.9 0.0 0.0086 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EGO20950.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 EGO20950.1 - 0.05 14.3 0.0 0.37 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 EGO20950.1 - 0.073 12.8 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 EGO20950.1 - 0.095 13.4 0.0 0.88 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Asn_synthase PF00733.21 EGO20951.1 - 1.9e-95 320.6 0.2 2.2e-56 192.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGO20951.1 - 1.6e-34 118.5 0.0 2.6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGO20951.1 - 2.3e-28 99.0 0.0 4.8e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGO20951.1 - 0.00021 20.8 0.0 0.0005 19.6 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.13 EGO20951.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 EGO20951.1 - 0.043 12.9 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Aldo_ket_red PF00248.21 EGO20952.1 - 3.4e-52 177.5 0.0 3.8e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Syntaxin PF00804.25 EGO20953.1 - 2.2e-31 109.1 10.1 2.2e-31 109.1 10.1 1.6 2 0 0 2 2 1 1 Syntaxin Syntaxin_2 PF14523.6 EGO20953.1 - 5.4e-09 36.3 12.5 1e-08 35.4 7.8 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGO20953.1 - 1.6e-08 34.4 0.1 4.4e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 SNARE domain FUSC PF04632.12 EGO20953.1 - 0.00098 17.8 1.6 0.00098 17.8 1.6 2.2 1 1 1 2 2 2 1 Fusaric acid resistance protein family HHH_2 PF12826.7 EGO20953.1 - 0.0021 18.1 0.3 0.0055 16.8 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Laminin_II PF06009.12 EGO20953.1 - 0.003 17.6 5.3 0.12 12.4 0.1 2.6 3 0 0 3 3 2 1 Laminin Domain II BLOC1_2 PF10046.9 EGO20953.1 - 0.0045 17.2 9.9 0.1 12.9 0.5 3.6 3 1 1 4 4 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 EGO20953.1 - 0.0095 16.4 9.0 0.71 10.4 0.2 3.1 3 0 0 3 3 3 2 Spectrin repeat APG17 PF04108.12 EGO20953.1 - 0.011 14.8 16.1 0.1 11.7 6.0 2.9 1 1 1 2 2 2 0 Autophagy protein Apg17 Synaptobrevin PF00957.21 EGO20953.1 - 0.024 14.4 3.2 0.096 12.5 0.0 2.7 2 1 1 3 3 3 0 Synaptobrevin VitD-bind_III PF09164.10 EGO20953.1 - 0.03 14.3 0.3 0.083 12.9 0.0 1.8 2 0 0 2 2 1 0 Vitamin D binding protein, domain III SKA1 PF07160.12 EGO20953.1 - 0.044 13.6 0.4 0.044 13.6 0.4 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DASH_Dam1 PF08653.10 EGO20953.1 - 0.055 13.3 2.7 0.16 11.8 0.1 2.6 3 0 0 3 3 2 0 DASH complex subunit Dam1 TMCO5 PF14992.6 EGO20953.1 - 0.069 12.7 7.3 3.4 7.2 3.7 2.1 2 0 0 2 2 2 0 TMCO5 family DUF1659 PF07872.11 EGO20953.1 - 0.13 11.9 0.6 0.41 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) V_ATPase_I PF01496.19 EGO20953.1 - 0.13 10.1 12.2 0.043 11.7 4.9 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 EGO20953.1 - 0.3 11.4 6.3 4.8 7.5 0.6 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PCRF PF03462.18 EGO20953.1 - 0.54 10.1 12.2 0.21 11.4 1.5 2.6 1 1 1 2 2 2 0 PCRF domain NleF_casp_inhib PF16809.5 EGO20953.1 - 0.67 9.9 6.6 0.27 11.1 1.9 2.2 2 1 0 2 2 2 0 NleF caspase inhibitor HsbA PF12296.8 EGO20953.1 - 0.71 10.3 6.6 1.8 9.0 3.2 2.5 2 1 0 2 2 2 0 Hydrophobic surface binding protein A FapA PF03961.13 EGO20953.1 - 0.73 8.4 7.9 0.35 9.4 1.7 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 EGO20953.1 - 0.89 10.1 5.2 17 5.9 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 EGO20953.1 - 0.97 8.9 7.0 1.1 8.8 1.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein NAP PF00956.18 EGO20953.1 - 1 8.4 8.1 0.35 10.0 4.2 2.1 2 1 0 2 2 2 0 Nucleosome assembly protein (NAP) COG5 PF10392.9 EGO20953.1 - 1.3 9.2 7.3 0.23 11.7 1.8 2.3 3 0 0 3 3 2 0 Golgi transport complex subunit 5 LOH1CR12 PF10158.9 EGO20953.1 - 1.5 8.9 5.4 2.4 8.2 0.1 2.8 2 1 0 2 2 2 0 Tumour suppressor protein DUF2939 PF11159.8 EGO20953.1 - 1.8 9.0 5.1 1 9.8 0.4 2.9 3 1 1 4 4 3 0 Protein of unknown function (DUF2939) Fib_alpha PF08702.10 EGO20953.1 - 2.5 8.3 11.2 13 6.0 0.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EGO20953.1 - 4.1 7.5 10.3 15 5.7 0.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 EGO20953.1 - 4.8 7.7 9.5 0.44 11.0 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 ACCA PF03255.14 EGO20953.1 - 6.1 6.7 9.6 1.7 8.5 0.4 2.9 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4094 PF13334.6 EGO20953.1 - 6.6 7.2 7.4 11 6.5 0.1 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4094) V-SNARE PF05008.15 EGO20953.1 - 7.2 7.1 17.6 0.17 12.3 0.6 4.4 3 3 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus CDP-OH_P_transf PF01066.21 EGO20954.1 - 2.8e-13 50.4 0.4 2.8e-13 50.4 0.4 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AAA PF00004.29 EGO20955.1 - 4.5e-36 124.2 0.0 1.1e-35 122.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO20955.1 - 1.1e-10 41.2 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO20955.1 - 2.5e-05 24.7 0.0 0.0046 17.3 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGO20955.1 - 0.00058 19.9 0.0 0.007 16.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGO20955.1 - 0.0008 20.0 0.1 0.033 14.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGO20955.1 - 0.0012 19.2 0.1 0.028 14.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO20955.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO20955.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 EGO20955.1 - 0.014 14.4 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_11 PF13086.6 EGO20955.1 - 0.015 15.1 1.0 0.13 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGO20955.1 - 0.017 15.1 0.0 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 EGO20955.1 - 0.03 14.3 0.3 0.065 13.2 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGO20955.1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EGO20955.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGO20955.1 - 0.059 12.6 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 EGO20955.1 - 0.089 13.1 0.6 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO20955.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EGO20955.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGO20955.1 - 0.18 11.2 0.2 0.41 10.0 0.2 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_Nse1 PF07574.13 EGO20956.1 - 3.5e-25 89.0 0.1 1.4e-23 83.9 0.1 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex CDP-OH_P_transf PF01066.21 EGO20957.1 - 3.6e-12 46.9 0.7 1.4e-11 45.0 0.7 2.0 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DNA_primase_lrg PF04104.14 EGO20958.1 - 1.8e-83 280.0 0.0 2.9e-83 279.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit BASP1 PF05466.12 EGO20960.1 - 0.028 14.5 5.8 0.049 13.6 5.6 1.6 1 1 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) USP7_ICP0_bdg PF12436.8 EGO20961.1 - 1e-85 286.9 0.5 7.7e-85 284.0 0.1 2.6 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGO20961.1 - 2.1e-69 233.4 2.9 5.6e-65 218.9 0.2 2.9 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGO20961.1 - 1.6e-50 172.0 0.1 2.4e-50 171.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO20961.1 - 2.1e-21 76.9 0.0 4.7e-21 75.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EGO20961.1 - 7.1e-08 32.6 0.0 3.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 MATH domain Sec66 PF09802.9 EGO20962.1 - 1.7e-57 193.9 0.1 2.2e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SieB PF14163.6 EGO20962.1 - 0.16 11.5 0.0 0.72 9.3 0.0 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B Citrate_synt PF00285.21 EGO20963.1 - 1.2e-100 337.1 0.0 1.3e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Toprim_4 PF13662.6 EGO20963.1 - 0.087 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Toprim domain B56 PF01603.20 EGO20964.1 - 3.4e-192 639.0 5.9 4e-192 638.7 5.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) ATP-cone PF03477.16 EGO20964.1 - 0.09 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 ATP cone domain HSP70 PF00012.20 EGO20965.1 - 2.1e-262 871.7 3.5 2.4e-262 871.5 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO20965.1 - 2.6e-15 56.1 0.0 3.9e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGO20965.1 - 0.0024 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EGO20965.1 - 0.031 13.5 0.1 0.077 12.2 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EGO20965.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein MutS_III PF05192.18 EGO20965.1 - 1.9 8.7 6.3 1.2 9.3 1.0 2.3 2 1 0 2 2 2 0 MutS domain III RabGAP-TBC PF00566.18 EGO20969.1 - 1e-11 44.9 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AflR PF08493.10 EGO20969.1 - 1.3 8.5 5.5 22 4.4 4.4 2.4 2 1 0 2 2 2 0 Aflatoxin regulatory protein FAD_binding_2 PF00890.24 EGO20970.1 - 4.2e-126 421.4 2.2 5.3e-126 421.1 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGO20970.1 - 8.5e-43 145.4 0.2 1.3e-42 144.8 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EGO20970.1 - 6.4e-06 25.5 2.3 0.0098 15.0 2.2 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 EGO20970.1 - 4.2e-05 22.9 0.1 0.032 13.5 0.0 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.14 EGO20970.1 - 6.1e-05 22.4 0.3 0.0019 17.5 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO20970.1 - 0.0027 17.0 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGO20970.1 - 0.066 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EGO20970.1 - 0.11 12.1 1.5 0.21 11.1 1.5 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO20970.1 - 0.16 10.6 2.2 0.5 9.0 0.8 2.5 4 0 0 4 4 4 0 HI0933-like protein Sgf11 PF08209.11 EGO20972.1 - 2.8e-14 52.4 0.2 5.6e-14 51.4 0.2 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zinc_ribbon_10 PF10058.9 EGO20972.1 - 0.16 11.7 1.0 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ABC_membrane_2 PF06472.15 EGO20973.1 - 1.5e-86 290.2 1.0 2e-86 289.7 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGO20973.1 - 5.8e-17 62.5 0.0 1.3e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO20973.1 - 5.7e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO20973.1 - 0.00011 21.9 0.2 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO20973.1 - 0.014 15.9 0.0 0.014 15.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGO20973.1 - 0.017 14.5 0.0 0.059 12.8 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SHR3_chaperone PF08229.11 EGO20974.1 - 8.8e-28 96.6 1.9 1e-27 96.4 1.9 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.6 EGO20974.1 - 0.067 13.6 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Chs7 PF12271.8 EGO20974.1 - 0.11 11.8 1.9 0.15 11.4 1.9 1.1 1 0 0 1 1 1 0 Chitin synthase export chaperone LETM1 PF07766.13 EGO20975.1 - 5.8e-104 347.2 0.1 5.8e-104 347.2 0.1 2.2 2 1 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EGO20975.1 - 0.0015 18.3 0.6 0.021 14.6 0.0 3.1 3 0 0 3 3 3 1 SAP domain EF-hand_6 PF13405.6 EGO20975.1 - 0.0058 16.5 0.0 3.5 7.8 0.0 3.9 3 0 0 3 3 3 1 EF-hand domain DUF5063 PF16702.5 EGO20975.1 - 0.013 15.9 0.6 0.029 14.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) EF-hand_1 PF00036.32 EGO20975.1 - 0.046 13.3 0.2 0.81 9.4 0.0 3.0 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 EGO20975.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.7 3 1 2 5 5 5 0 EF-hand domain pair Peptidase_S46 PF10459.9 EGO20975.1 - 7.7 5.0 9.7 12 4.4 9.7 1.1 1 0 0 1 1 1 0 Peptidase S46 2OG-FeII_Oxy_2 PF13532.6 EGO20976.1 - 8.5e-36 124.0 0.0 7.6e-34 117.6 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily GPI PF06560.11 EGO20977.1 - 0.058 12.7 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Glycos_transf_1 PF00534.20 EGO20978.1 - 6.4e-19 68.1 0.0 1.5e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO20978.1 - 3e-12 47.1 0.0 5.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGO20978.1 - 7.4e-05 23.1 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO20978.1 - 0.059 13.4 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Fe-ADH PF00465.19 EGO20979.1 - 0.12 11.2 0.5 0.15 10.8 0.5 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DNA_pol_phi PF04931.13 EGO20980.1 - 3.8e-229 762.7 11.5 3.8e-229 762.7 11.5 1.8 2 0 0 2 2 2 1 DNA polymerase phi Q_salvage PF10343.9 EGO20980.1 - 0.02 14.5 0.8 0.059 12.9 0.4 2.0 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family eIF3_N PF09440.10 EGO20980.1 - 0.083 13.3 0.5 0.34 11.3 0.1 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain MutS_V PF00488.21 EGO20981.1 - 1.7e-66 223.9 0.3 3.1e-66 223.0 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO20981.1 - 5e-35 121.5 0.4 1.4e-34 120.0 0.2 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGO20981.1 - 5.5e-18 65.3 0.5 1.3e-17 64.1 0.2 1.8 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EGO20981.1 - 4.2e-05 23.8 0.1 0.00013 22.2 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGO20981.1 - 0.00049 20.4 0.1 0.0021 18.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain II ATP12 PF07542.11 EGO20982.1 - 1.5e-41 141.5 0.1 2.7e-41 140.7 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Nt_Gln_amidase PF09764.9 EGO20983.1 - 5.5e-56 189.1 0.0 6.1e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase BTB PF00651.31 EGO20984.1 - 0.0026 17.9 0.0 0.0043 17.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.26 EGO20986.1 - 4.1e-42 143.2 0.0 4.6e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO20986.1 - 0.0025 17.5 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGO20986.1 - 0.048 13.5 0.1 0.092 12.6 0.1 1.3 1 1 0 1 1 1 0 UEV domain SPRY PF00622.28 EGO20987.1 - 1.5e-09 38.0 0.0 3.9e-07 30.2 0.0 3.2 3 0 0 3 3 3 1 SPRY domain PhoD PF09423.10 EGO20988.1 - 0.094 11.7 0.0 0.64 9.0 0.0 2.2 3 0 0 3 3 3 0 PhoD-like phosphatase CAP_N PF01213.19 EGO20989.1 - 1.8e-110 369.4 0.0 2.6e-110 368.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGO20989.1 - 1.1e-58 197.3 6.3 1.5e-58 196.9 6.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGO20989.1 - 0.39 10.5 5.3 0.31 10.8 2.5 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor C RF-1 PF00472.20 EGO20990.1 - 1.1e-22 80.1 7.3 1.1e-22 80.1 7.3 1.8 2 0 0 2 2 2 1 RF-1 domain Linker_histone PF00538.19 EGO20991.1 - 2.5e-24 85.4 0.3 5.4e-24 84.3 0.0 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family Cbl_N3 PF02762.14 EGO20991.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain p450 PF00067.22 EGO20992.1 - 1.2e-70 238.6 0.0 9.8e-70 235.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 EI24 PF07264.11 EGO20993.1 - 8.3e-37 127.1 11.9 1.1e-36 126.7 11.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.6 EGO20993.1 - 0.012 15.9 1.5 0.1 12.9 1.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) Lipase_GDSL_2 PF13472.6 EGO20995.1 - 7.3e-29 101.4 0.0 8.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO20995.1 - 5.6e-15 55.8 0.0 7.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.20 EGO20996.1 - 5.9e-14 52.5 0.0 1.4e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.24 EGO20997.1 - 7.5e-147 489.9 11.7 8.5e-147 489.7 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EGO20997.1 - 0.013 15.0 0.1 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 Telomere recombination TPR_2 PF07719.17 EGO20998.1 - 4.8e-30 101.2 2.9 0.00019 21.3 0.2 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGO20998.1 - 1.3e-27 94.4 3.5 6.4e-08 32.1 0.3 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO20998.1 - 5.4e-23 81.0 11.3 1.2e-15 57.4 1.5 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGO20998.1 - 4.9e-20 71.8 5.3 3e-06 27.7 0.0 6.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO20998.1 - 2.4e-19 69.7 10.5 4.5e-05 24.0 0.0 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO20998.1 - 3.6e-16 58.6 0.1 0.1 12.3 0.0 7.5 6 1 1 7 7 7 4 TPR repeat TPR_17 PF13431.6 EGO20998.1 - 3.8e-16 58.2 5.4 0.069 13.6 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO20998.1 - 4.2e-14 51.5 0.4 0.22 11.8 0.1 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO20998.1 - 2.7e-13 49.5 16.7 0.27 12.1 0.0 9.8 4 1 6 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO20998.1 - 1.3e-10 41.4 12.9 0.0027 17.9 0.1 7.4 5 1 4 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGO20998.1 - 1.3e-08 34.9 8.7 0.0033 17.6 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO20998.1 - 3.6e-07 29.8 2.3 1.4 9.2 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGO20998.1 - 5.1e-07 29.9 12.5 0.9 10.3 0.0 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat PPTA PF01239.22 EGO20998.1 - 0.0028 17.3 0.1 0.45 10.3 0.0 2.7 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat TPR_15 PF13429.6 EGO20998.1 - 0.025 13.8 15.3 0.11 11.6 0.1 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGO20998.1 - 0.071 13.5 0.4 19 5.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TBCC_N PF16752.5 EGO20998.1 - 0.089 13.2 0.1 0.34 11.4 0.0 2.1 2 0 0 2 2 1 0 Tubulin-specific chaperone C N-terminal domain ChAPs PF09295.10 EGO20998.1 - 0.16 10.9 0.0 6.2 5.7 0.0 2.4 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EGO20998.1 - 2.2 8.3 10.7 11 6.0 0.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat SRR1 PF07985.12 EGO21000.1 - 1.3e-15 57.2 1.0 2.3e-15 56.4 1.0 1.4 1 0 0 1 1 1 1 SRR1 Pre-PUA PF17832.1 EGO21001.1 - 4.4e-26 91.4 0.2 5.8e-26 91.0 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGO21001.1 - 9.1e-15 54.4 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EGO21001.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) CRM1_C PF08767.11 EGO21002.1 - 9.5e-133 442.3 0.1 9.5e-133 442.3 0.1 3.1 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EGO21002.1 - 3e-42 144.2 5.5 1.2e-40 139.0 6.7 3.0 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGO21002.1 - 8.8e-34 115.0 4.5 2e-33 113.8 4.5 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGO21002.1 - 1.6e-30 104.9 1.2 1.6e-30 104.9 1.2 3.2 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGO21002.1 - 1.5e-18 66.0 2.4 1.5e-18 66.0 2.4 2.4 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGO21002.1 - 7.5e-14 51.4 0.0 2.7e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EGO21002.1 - 0.042 13.8 0.0 0.42 10.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EGO21002.1 - 0.52 10.9 2.6 11 6.8 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ADH_zinc_N_2 PF13602.6 EGO21003.1 - 1.1e-19 71.8 0.0 2.1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO21003.1 - 1.1e-13 51.3 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO21003.1 - 0.015 15.2 0.0 0.073 13.0 0.0 2.1 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGO21003.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase E1-E2_ATPase PF00122.20 EGO21004.1 - 2e-53 180.6 1.1 2e-53 180.6 1.1 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO21004.1 - 1.2e-45 155.4 7.6 1.2e-45 155.4 7.6 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO21004.1 - 1.9e-22 80.6 1.5 7.7e-21 75.3 1.5 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO21004.1 - 8.8e-20 70.2 2.0 9.1e-20 70.1 0.0 2.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGO21004.1 - 1.2e-18 67.0 0.0 2.5e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO21004.1 - 5.3e-07 29.6 1.3 4e-06 26.7 1.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO21004.1 - 2.8e-06 27.8 0.0 6.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FliO PF04347.13 EGO21005.1 - 0.11 12.8 0.1 0.45 10.8 0.0 2.0 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO Hamartin PF04388.12 EGO21005.1 - 0.67 8.5 10.3 0.94 8.1 10.3 1.4 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 EGO21005.1 - 5.7 5.6 10.5 11 4.8 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 EGO21005.1 - 9.4 4.7 12.1 12 4.3 12.1 1.1 1 0 0 1 1 1 0 Macoilin family CBP4 PF07960.11 EGO21006.1 - 8.8e-09 35.3 0.0 9.5e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF3464 PF11947.8 EGO21006.1 - 0.44 10.3 2.8 0.31 10.8 0.9 1.6 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 DUF4748 PF15932.5 EGO21006.1 - 0.52 10.1 2.4 1 9.2 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Arrestin_C PF02752.22 EGO21007.1 - 0.00024 21.5 0.0 1.2 9.5 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain TPT PF03151.16 EGO21008.1 - 5e-08 32.6 3.1 7.6e-05 22.2 0.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EGO21008.1 - 9.5e-08 32.3 27.3 2e-05 24.8 2.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGO21008.1 - 2.1e-06 27.2 9.3 3.9e-06 26.3 9.3 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EGO21008.1 - 3.5e-06 26.4 4.4 5.5e-06 25.8 4.4 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter MitoNEET_N PF10660.9 EGO21008.1 - 0.018 15.1 0.3 0.066 13.3 0.3 2.0 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus UPF0182 PF03699.13 EGO21008.1 - 1.2 7.1 4.8 0.18 9.9 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) SHQ1 PF04925.15 EGO21010.1 - 6.1e-56 188.8 0.0 9.6e-56 188.1 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 EGO21010.1 - 0.00062 20.1 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 EGO21010.1 - 0.0015 19.5 0.0 0.0028 18.6 0.0 1.5 1 0 0 1 1 1 1 CS domain Chorismate_bind PF00425.18 EGO21011.1 - 3.3e-89 298.9 0.0 4.6e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGO21011.1 - 1.8e-27 96.3 0.0 8.2e-27 94.2 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.20 EGO21012.1 - 9.2e-54 181.9 0.0 4.6e-31 107.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HSP70 PF00012.20 EGO21013.1 - 7.9e-236 783.9 5.1 9.5e-236 783.7 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO21013.1 - 7.8e-16 57.8 0.4 8e-15 54.5 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EGO21013.1 - 0.014 14.4 0.8 0.15 11.0 0.8 2.2 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 EGO21013.1 - 0.022 14.3 0.2 3.6 7.0 0.0 2.6 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 EGO21013.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EGO21013.1 - 0.077 12.2 0.2 0.18 11.0 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EGO21013.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 StbA protein Gag_p24 PF00607.20 EGO21013.1 - 0.11 12.4 0.4 2.2 8.1 0.2 2.3 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) zf-ZPR1 PF03367.13 EGO21013.1 - 0.13 12.1 0.7 0.38 10.6 0.7 1.8 1 0 0 1 1 1 0 ZPR1 zinc-finger domain ATP-synt_DE PF00401.20 EGO21013.1 - 3.9 7.8 8.4 15 5.9 6.1 2.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain AAA PF00004.29 EGO21014.1 - 5.3e-14 52.8 0.0 1.2e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGO21014.1 - 3.6e-11 43.1 0.0 1.8e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGO21014.1 - 1.8e-10 41.1 0.0 4.7e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EGO21014.1 - 1.2e-07 31.8 0.0 3.3e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGO21014.1 - 2.2e-05 24.8 0.0 8.7e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EGO21014.1 - 4.8e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 EGO21014.1 - 0.00011 22.0 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO21014.1 - 0.00012 22.5 0.1 0.00057 20.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGO21014.1 - 0.00026 20.8 0.0 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO21014.1 - 0.00072 19.6 0.0 0.0033 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO21014.1 - 0.00082 19.2 0.1 0.002 17.9 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EGO21014.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO21014.1 - 0.0035 16.9 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGO21014.1 - 0.0043 16.5 0.0 0.044 13.2 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGO21014.1 - 0.011 16.1 0.0 0.078 13.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EGO21014.1 - 0.013 15.5 0.0 0.074 13.1 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EGO21014.1 - 0.04 13.1 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EGO21014.1 - 0.052 13.3 0.1 0.56 10.0 0.0 2.5 1 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 EGO21014.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO21014.1 - 0.077 13.5 0.0 0.18 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO21014.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 EGO21014.1 - 0.086 13.3 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain HTH_7 PF02796.15 EGO21014.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase CAF1A PF12253.8 EGO21015.1 - 9.1e-23 80.2 1.5 9.1e-23 80.2 1.5 3.5 3 1 1 4 4 4 1 Chromatin assembly factor 1 subunit A Spc24 PF08286.11 EGO21016.1 - 4.7e-19 68.6 0.0 1.9e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APG6_N PF17675.1 EGO21016.1 - 0.031 14.8 5.7 0.053 14.1 5.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FAM76 PF16046.5 EGO21016.1 - 0.48 9.7 1.6 0.58 9.5 1.6 1.1 1 0 0 1 1 1 0 FAM76 protein gag-asp_proteas PF13975.6 EGO21019.1 - 5e-07 30.2 0.0 8.1e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO21019.1 - 1.6e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO21019.1 - 7.1e-06 26.6 0.0 9.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Pollen_Ole_e_I PF01190.17 EGO21019.1 - 0.033 14.6 0.1 2.9 8.3 0.0 2.0 1 1 1 2 2 2 0 Pollen proteins Ole e I like Asp_protease PF09668.10 EGO21019.1 - 0.065 13.0 0.0 0.072 12.9 0.0 1.3 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 EGO21020.1 - 6.1e-10 39.3 8.2 3e-06 27.4 1.1 3.5 3 0 0 3 3 3 2 Retrotransposon gag protein zf-CCHC PF00098.23 EGO21020.1 - 0.0037 17.3 4.1 0.0058 16.7 4.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Peptidase_M60_C PF18630.1 EGO21020.1 - 0.15 12.2 0.1 27 5.0 0.0 2.4 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain RCC1 PF00415.18 EGO21023.1 - 6e-20 71.6 11.1 4.2e-07 30.5 0.1 7.8 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO21023.1 - 1e-10 41.1 26.7 1.5e-06 27.8 0.4 7.6 7 1 1 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat PQQ_3 PF13570.6 EGO21024.1 - 0.00015 22.1 0.5 0.0066 16.9 0.0 3.3 4 0 0 4 4 4 1 PQQ-like domain WD40 PF00400.32 EGO21024.1 - 0.00022 21.9 3.8 0.0014 19.4 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGO21024.1 - 0.0068 16.4 0.0 2.8 8.0 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Reg_prop PF07494.11 EGO21024.1 - 0.041 14.1 0.2 17 6.1 0.1 3.8 3 0 0 3 3 3 0 Two component regulator propeller Gln-synt_C PF00120.24 EGO21025.1 - 5e-78 262.5 0.0 1.1e-77 261.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3074 PF11274.8 EGO21026.1 - 1.3e-42 145.9 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ribosomal_L27 PF01016.19 EGO21027.1 - 1e-33 115.2 1.3 1.4e-33 114.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 EGO21027.1 - 0.033 14.0 0.4 0.46 10.3 0.1 2.6 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Skp1 PF01466.19 EGO21028.1 - 2.7e-29 101.0 0.5 4.7e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGO21028.1 - 1.9e-24 85.6 1.5 2.8e-24 85.0 0.1 2.0 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGO21028.1 - 0.00016 21.8 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.14 EGO21028.1 - 0.087 12.8 0.1 0.17 11.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF615) mRNA_cap_enzyme PF01331.19 EGO21029.1 - 3.7e-52 177.0 0.0 5.2e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGO21029.1 - 1.9e-30 105.7 0.0 3.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EGO21029.1 - 1.9e-10 40.8 0.0 1.5e-07 31.2 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EGO21029.1 - 0.0024 18.2 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase Amidohydro_1 PF01979.20 EGO21031.1 - 1.1e-61 209.0 0.0 1.1e-50 172.9 0.0 2.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EGO21031.1 - 8.1e-07 28.9 0.0 0.039 13.4 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family SelP_N PF04592.14 EGO21031.1 - 0.0003 20.2 10.5 0.0005 19.6 10.5 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Lipase_3 PF01764.25 EGO21032.1 - 1.4e-06 28.2 0.0 4.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO21032.1 - 0.0004 21.0 1.4 0.00057 20.5 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EGO21032.1 - 0.029 14.3 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 EGO21032.1 - 0.048 13.3 0.2 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO21032.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGO21032.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein CTP_transf_like PF01467.26 EGO21033.1 - 1.3e-09 38.4 0.0 2.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EGO21033.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase DHHC PF01529.20 EGO21035.1 - 1.1e-35 122.7 8.0 1.8e-35 121.9 8.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Sensor PF13796.6 EGO21035.1 - 0.012 15.7 0.4 0.012 15.7 0.4 2.2 2 0 0 2 2 2 0 Putative sensor Fungal_trans PF04082.18 EGO21037.1 - 3.1e-22 78.9 0.1 1.6e-21 76.5 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain LIM PF00412.22 EGO21038.1 - 8.5e-21 73.9 20.2 5.4e-11 42.5 6.2 3.2 3 0 0 3 3 3 3 LIM domain WRC PF08879.10 EGO21038.1 - 0.076 12.7 5.2 4.5 7.0 0.2 3.8 3 0 0 3 3 3 0 WRC Vps39_2 PF10367.9 EGO21038.1 - 0.08 13.4 2.6 2.1 8.8 0.1 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2321 PF10083.9 EGO21038.1 - 0.61 9.7 6.5 0.15 11.7 3.4 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) PolC_DP2 PF03833.13 EGO21038.1 - 1.8 6.3 3.1 2.3 6.0 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-FLZ PF04570.14 EGO21038.1 - 3.8 7.1 12.5 5.1 6.6 0.2 3.6 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 Syja_N PF02383.18 EGO21039.1 - 2.1e-93 313.2 0.0 3.1e-93 312.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EGO21039.1 - 2.3e-31 107.9 0.0 5.7e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase Proteasome PF00227.26 EGO21040.1 - 5.4e-49 166.3 0.1 6.5e-49 166.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cys_Met_Meta_PP PF01053.20 EGO21041.1 - 6.9e-59 199.3 0.0 2.3e-58 197.6 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cys_Met_Meta_PP PF01053.20 EGO21042.1 - 1.2e-44 152.5 0.0 2.3e-44 151.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FMO-like PF00743.19 EGO21044.1 - 1.7e-36 125.8 0.0 3.4e-23 81.9 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO21044.1 - 1.5e-15 57.2 0.1 2.8e-12 46.5 0.2 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO21044.1 - 4.1e-12 45.9 0.0 4.1e-11 42.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO21044.1 - 1.7e-06 28.1 1.6 0.017 15.1 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO21044.1 - 5.8e-05 23.2 0.0 0.0006 20.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO21044.1 - 0.00023 20.5 0.5 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EGO21044.1 - 0.0046 16.3 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGO21044.1 - 0.046 12.4 3.0 0.35 9.5 0.2 3.0 3 1 1 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 EGO21044.1 - 0.075 12.3 2.0 0.49 9.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 EGO21044.1 - 0.24 10.7 1.9 3.3 7.0 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EGO21044.1 - 1.6 8.2 4.6 7.7 6.0 0.3 3.4 3 1 0 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 EGO21044.1 - 2.2 7.3 3.4 2.2 7.3 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CDH-cyt PF16010.5 EGO21045.1 - 5.7e-49 166.3 0.2 7.4e-49 165.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 EGO21045.1 - 8.4e-10 38.4 13.0 8.4e-10 38.4 13.0 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain DOMON PF03351.17 EGO21045.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 DOMON domain CDH-cyt PF16010.5 EGO21046.1 - 2.4e-48 164.2 0.2 2.7e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Ribosomal_L7Ae PF01248.26 EGO21047.1 - 2.5e-05 23.9 0.1 2.8e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UQ_con PF00179.26 EGO21048.1 - 2.1e-48 163.6 0.0 2.3e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO21048.1 - 0.00071 19.3 0.0 0.00086 19.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGO21048.1 - 0.088 13.1 1.1 0.14 12.5 1.1 1.6 1 1 0 1 1 1 0 RWD domain DNA_binding_1 PF01035.20 EGO21049.1 - 4e-16 58.9 0.1 5e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Gelsolin PF00626.22 EGO21050.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat DUF3040 PF11239.8 EGO21051.1 - 0.016 15.4 0.6 0.019 15.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4710 PF15828.5 EGO21051.1 - 0.23 11.6 0.0 0.27 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF1713 PF08213.11 EGO21053.1 - 1.9e-06 27.7 17.5 2.8e-06 27.1 17.5 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Glyco_transf_22 PF03901.17 EGO21054.1 - 7.4e-66 223.1 22.6 1.4e-63 215.6 22.6 2.9 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3835 PF12927.7 EGO21056.1 - 1.7e-07 32.0 2.4 3.7e-06 27.7 0.1 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) SLY PF12485.8 EGO21056.1 - 0.54 11.0 9.0 0.15 12.8 4.5 2.4 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein KH_8 PF17903.1 EGO21057.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGO21057.1 - 0.0027 17.5 0.8 0.0058 16.4 0.8 1.5 1 0 0 1 1 1 1 KH domain Pribosyltran PF00156.27 EGO21058.1 - 2.9e-08 33.4 0.1 5.1e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 EGO21058.1 - 7.1e-08 32.4 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGO21058.1 - 7.7e-06 26.1 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGO21058.1 - 0.048 12.6 0.1 0.5 9.2 0.1 2.1 1 1 1 2 2 2 0 Glutamine amidotransferases class-II S-AdoMet_synt_C PF02773.16 EGO21059.1 - 5.2e-66 220.8 0.2 1.1e-65 219.8 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGO21059.1 - 4.2e-46 156.1 0.0 7.7e-46 155.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGO21059.1 - 1.2e-45 154.2 0.2 2.6e-45 153.2 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGO21059.1 - 0.0034 16.2 0.3 0.17 10.7 0.0 2.2 2 0 0 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) Amidinotransf PF02274.17 EGO21059.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase Myotub-related PF06602.14 EGO21060.1 - 3e-150 500.1 0.0 3.6e-150 499.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGO21060.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CBF PF03914.17 EGO21061.1 - 5.2e-32 111.2 2.9 2.3e-29 102.6 2.2 3.1 3 0 0 3 3 3 2 CBF/Mak21 family MOR2-PAG1_C PF14225.6 EGO21061.1 - 0.0035 17.3 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Cu_bind_like PF02298.17 EGO21062.1 - 0.0012 18.8 0.3 0.0045 17.0 0.3 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain G-gamma PF00631.22 EGO21063.1 - 2.8e-22 78.5 0.0 3.1e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.22 EGO21064.1 - 2.3e-23 82.0 0.0 2.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 GGL domain TRAM_LAG1_CLN8 PF03798.16 EGO21065.1 - 4.8e-28 98.3 19.9 5.3e-28 98.1 16.2 2.0 2 0 0 2 2 2 1 TLC domain SLC3A2_N PF16028.5 EGO21065.1 - 0.27 10.8 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Vps54 PF07928.12 EGO21066.1 - 6.2e-52 175.6 0.9 6.2e-52 175.6 0.9 2.3 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 EGO21066.1 - 2.9e-06 26.8 0.0 7.3e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGO21066.1 - 4.1e-05 23.5 0.5 8.4e-05 22.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) SepF PF04472.12 EGO21066.1 - 0.057 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Cell division protein SepF PPR PF01535.20 EGO21066.1 - 0.19 12.0 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 PPR repeat WD40 PF00400.32 EGO21068.1 - 1.9e-36 123.5 14.8 1.5e-07 32.0 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21068.1 - 1.1e-12 48.0 3.1 0.012 15.8 0.0 5.0 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO21068.1 - 0.0012 17.9 0.4 0.062 12.3 0.1 3.1 2 2 0 3 3 3 1 Coatomer WD associated region SGL PF08450.12 EGO21068.1 - 0.014 15.0 0.0 0.16 11.5 0.0 2.6 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Pkinase_fungal PF17667.1 EGO21069.1 - 9.6e-21 74.0 0.0 1.1e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase ORC3_N PF07034.11 EGO21070.1 - 0.0075 15.4 0.4 0.0075 15.4 0.4 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Uso1_p115_C PF04871.13 EGO21070.1 - 0.035 14.5 0.1 0.043 14.2 0.1 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4722 PF15849.5 EGO21071.1 - 0.033 13.9 0.1 0.2 11.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4722) WD40 PF00400.32 EGO21073.1 - 1.6e-35 120.5 16.2 9.3e-08 32.6 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21073.1 - 1.1e-11 44.8 3.0 0.013 15.8 0.1 5.0 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO21073.1 - 0.012 14.6 0.1 0.86 8.6 0.0 3.2 3 1 1 4 4 4 0 Coatomer WD associated region SGL PF08450.12 EGO21073.1 - 0.017 14.7 0.0 0.42 10.2 0.0 2.6 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Cauli_VI PF01693.16 EGO21076.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin cwf18 PF08315.12 EGO21077.1 - 1.4e-33 116.4 11.2 1.4e-33 116.4 11.2 1.5 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor LepA_C PF06421.12 EGO21078.1 - 1.8e-44 150.2 0.1 3.2e-44 149.4 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 EGO21078.1 - 2.4e-35 121.9 0.0 3.8e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGO21078.1 - 4.7e-16 58.6 0.0 1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO21078.1 - 1.3e-07 31.9 0.2 2.7e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGO21078.1 - 8.9e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 EGO21078.1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 EGO21078.1 - 0.00044 20.1 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGO21078.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO21078.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGO21078.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain IF-2B PF01008.17 EGO21079.1 - 9.4e-65 218.6 0.0 1.1e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Porin_O_P PF07396.11 EGO21079.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphate-selective porin O and P Trp_syntA PF00290.20 EGO21080.1 - 3.1e-83 278.6 0.2 4.4e-83 278.1 0.2 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EGO21080.1 - 1.4e-46 159.3 0.3 2.8e-46 158.3 0.3 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 EGO21080.1 - 1.9e-05 24.2 0.2 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 EGO21080.1 - 0.00022 20.7 0.1 0.00037 20.0 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.17 EGO21080.1 - 0.0064 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase PA PF02225.22 EGO21080.1 - 0.012 15.7 0.1 9.4 6.3 0.0 2.8 2 0 0 2 2 2 0 PA domain GP46 PF07409.12 EGO21080.1 - 0.032 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Phage protein GP46 ThiG PF05690.14 EGO21080.1 - 0.033 13.5 1.3 0.17 11.1 0.4 2.2 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG DFP PF04127.15 EGO21080.1 - 0.066 13.0 0.1 5.7 6.7 0.1 2.2 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Asparaginase PF00710.20 EGO21081.1 - 1.3e-56 191.1 0.0 2.2e-56 190.4 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGO21081.1 - 2.9e-29 101.6 0.0 4.7e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Csm1 PF12539.8 EGO21082.1 - 0.0074 16.9 0.7 0.046 14.4 0.4 2.4 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF4953 PF16313.5 EGO21082.1 - 0.011 15.0 0.6 0.011 15.0 0.6 1.6 2 0 0 2 2 2 0 Met-zincin NPV_P10 PF05531.12 EGO21082.1 - 0.12 12.9 3.3 3.3 8.2 1.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 EGO21082.1 - 0.51 9.6 7.4 1 8.6 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 EGO21082.1 - 1.5 8.6 15.7 6.6 6.5 7.9 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tup_N PF08581.10 EGO21082.1 - 1.8 8.9 14.7 0.35 11.2 1.8 3.3 2 1 0 3 3 3 0 Tup N-terminal BLOC1_2 PF10046.9 EGO21082.1 - 2 8.7 8.4 11 6.4 0.4 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.11 EGO21082.1 - 7.9 6.8 11.9 7.9 6.8 1.5 3.1 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 A_deaminase PF00962.22 EGO21083.1 - 5.5e-23 81.8 0.0 7.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase PF00962.22 EGO21084.1 - 5.3e-25 88.4 0.0 3.1e-24 85.9 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EGO21084.1 - 0.0039 17.5 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal KH_1 PF00013.29 EGO21085.1 - 4e-43 145.1 9.0 4.5e-15 55.2 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGO21085.1 - 1.1e-15 57.2 7.4 2.6e-05 24.0 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGO21085.1 - 3.6e-06 26.8 2.2 0.068 13.1 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 EGO21085.1 - 0.00011 22.2 5.3 0.63 10.2 0.1 3.6 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EGO21085.1 - 0.055 13.5 0.0 4.3 7.4 0.0 3.1 4 0 0 4 4 4 0 KH-like RNA-binding domain Brix PF04427.18 EGO21086.1 - 1.1e-37 130.0 0.0 1.6e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 EGO21086.1 - 0.13 10.8 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin RPN2_C PF18004.1 EGO21086.1 - 5.8 6.8 10.8 3.3 7.6 2.6 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPDase PF07823.11 EGO21088.1 - 5.8e-21 75.1 0.0 7.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EGO21088.1 - 2.9e-09 37.0 0.1 5.2e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EGO21088.1 - 0.07 13.3 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF1776 PF08643.10 EGO21091.1 - 2.2e-15 56.8 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Arginase PF00491.21 EGO21091.1 - 0.046 13.2 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Arginase family PRIMA1 PF16101.5 EGO21091.1 - 0.048 13.7 0.3 0.048 13.7 0.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF973 PF06157.11 EGO21092.1 - 0.12 11.4 1.8 0.16 11.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) RicinB_lectin_2 PF14200.6 EGO21093.1 - 1e-05 26.2 2.9 0.0081 16.9 0.1 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like zf-CCHC PF00098.23 EGO21096.1 - 1.2e-07 31.5 1.2 1.6e-07 31.0 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO21096.1 - 0.012 15.2 0.3 0.017 14.7 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain zf-CCHC_6 PF15288.6 EGO21096.1 - 0.021 14.7 0.4 0.032 14.1 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle ATP-synt_ab PF00006.25 EGO21099.1 - 7e-63 212.1 0.0 1.1e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGO21099.1 - 8.9e-22 77.4 1.4 8.9e-22 77.4 1.4 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EGO21099.1 - 0.0045 16.2 0.7 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 EGO21099.1 - 0.03 14.2 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGO21099.1 - 0.03 14.7 0.1 0.085 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGO21099.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EGO21099.1 - 0.04 14.3 0.1 0.42 11.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGO21099.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EGO21099.1 - 0.071 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EGO21099.1 - 0.087 13.2 0.6 0.31 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 EGO21101.1 - 3.1e-43 148.1 0.0 6.4e-43 147.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO21101.1 - 7.4e-11 42.5 0.0 1.1e-06 29.1 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 EGO21101.1 - 1.1e-09 37.4 0.8 0.00078 19.2 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGO21101.1 - 1.8e-09 36.5 1.6 3.7e-05 23.0 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGO21101.1 - 1.2e-07 32.1 0.1 0.005 17.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGO21101.1 - 7.9e-05 22.0 2.7 0.012 15.1 1.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGO21101.1 - 0.00011 22.0 0.9 0.47 10.3 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 EGO21101.1 - 0.047 12.9 0.2 0.55 9.4 0.2 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.7 EGO21101.1 - 0.37 10.8 2.2 7.4 6.6 0.5 2.4 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand CLP1_N PF16573.5 EGO21102.1 - 3e-34 117.1 0.0 5.1e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 EGO21102.1 - 1e-32 113.4 0.0 2.4e-32 112.3 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGO21102.1 - 6.5e-28 97.5 0.0 1.4e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 SRPRB PF09439.10 EGO21102.1 - 0.031 13.7 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MFS_1 PF07690.16 EGO21103.1 - 1.7e-27 96.3 38.6 1.7e-27 96.3 36.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGO21103.1 - 0.00013 21.4 5.2 0.00013 21.4 5.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Transgly_assoc PF04226.13 EGO21103.1 - 2.8 8.3 12.6 6.6 7.1 1.6 3.5 2 0 0 2 2 2 0 Transglycosylase associated protein AAA PF00004.29 EGO21104.1 - 6.5e-15 55.7 0.0 3.3e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO21104.1 - 1.4e-05 24.9 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGO21104.1 - 0.00058 20.0 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO21104.1 - 0.00083 19.8 0.0 0.021 15.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 EGO21104.1 - 0.00091 19.2 0.0 0.0044 17.0 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 EGO21104.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EGO21104.1 - 0.0017 18.6 0.1 0.0062 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_22 PF13401.6 EGO21104.1 - 0.0052 17.1 0.0 0.19 12.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGO21104.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EGO21104.1 - 0.0069 16.0 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO21104.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GREB1 PF15782.5 EGO21104.1 - 0.036 11.2 0.0 0.05 10.7 0.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NTPase_1 PF03266.15 EGO21104.1 - 0.037 13.9 0.2 0.13 12.1 0.0 1.9 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 EGO21104.1 - 0.037 13.9 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EGO21104.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGO21104.1 - 0.058 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EGO21104.1 - 0.066 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGO21104.1 - 0.098 12.7 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGO21104.1 - 0.11 13.1 0.0 0.36 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO21104.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_2 PF07724.14 EGO21104.1 - 0.13 12.4 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Aminotran_1_2 PF00155.21 EGO21105.1 - 2.2e-14 53.4 0.0 2.9e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 EGO21106.1 - 4.3e-46 157.4 0.0 5.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21106.1 - 6.5e-46 156.7 0.0 8.1e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO21106.1 - 0.0083 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO21106.1 - 0.011 15.7 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAP PF02037.27 EGO21106.1 - 0.065 13.0 0.3 0.13 12.0 0.3 1.6 1 0 0 1 1 1 0 SAP domain Haspin_kinase PF12330.8 EGO21106.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1c PF00749.21 EGO21108.1 - 3.8e-109 364.4 0.0 5e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGO21108.1 - 6.9e-38 130.2 0.1 1.1e-37 129.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EGO21108.1 - 0.00027 20.9 0.1 0.00066 19.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO21108.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO21108.1 - 0.013 15.7 0.1 0.042 14.0 0.1 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EGO21108.1 - 0.037 13.4 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Bot1p PF12298.8 EGO21109.1 - 4.4e-11 43.3 0.0 4.8e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein PGC7_Stella PF15549.6 EGO21109.1 - 0.034 14.1 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain HMGL-like PF00682.19 EGO21111.1 - 2.6e-65 220.6 0.0 5.1e-46 157.4 0.0 2.3 1 1 1 2 2 2 2 HMGL-like LeuA_dimer PF08502.10 EGO21111.1 - 2.2e-47 160.3 0.0 7.9e-23 80.8 0.0 2.7 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain CTNNBL PF08216.11 EGO21111.1 - 0.19 11.9 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear APG9 PF04109.16 EGO21112.1 - 5.1e-208 691.9 7.7 6.1e-208 691.7 7.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 EF-hand_4 PF12763.7 EGO21113.1 - 0.038 14.0 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Thiamine_BP PF01910.17 EGO21114.1 - 1.7e-27 95.1 0.0 2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 EGO21114.1 - 0.00033 21.1 0.0 0.00043 20.7 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DNA_methylase PF00145.17 EGO21115.1 - 2.6e-44 152.0 0.0 1.8e-43 149.2 0.0 2.3 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EGO21115.1 - 4.7e-16 58.7 2.6 1.2e-08 34.9 0.0 3.0 2 1 0 2 2 2 2 BAH domain P_proprotein PF01483.20 EGO21116.1 - 4.9e-29 100.2 0.9 7.3e-29 99.6 0.3 1.6 2 0 0 2 2 2 1 Proprotein convertase P-domain DUF2914 PF11141.8 EGO21116.1 - 0.0036 17.0 0.8 0.0084 15.8 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2914) MCM PF00493.23 EGO21117.1 - 2.2e-105 350.7 0.0 3.8e-105 349.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO21117.1 - 1.3e-29 102.6 0.5 2.2e-29 101.9 0.5 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO21117.1 - 1.8e-20 73.1 1.1 4.6e-20 71.8 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO21117.1 - 3.3e-20 72.6 1.7 8.9e-20 71.2 1.7 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EGO21117.1 - 1.6e-09 37.9 0.1 9.5e-07 28.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGO21117.1 - 6.1e-08 32.3 0.1 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 EGO21117.1 - 0.001 19.6 0.6 0.001 19.6 0.6 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EGO21117.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EGO21117.1 - 0.076 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 EGO21117.1 - 0.1 12.3 0.1 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain zf_PR_Knuckle PF18445.1 EGO21118.1 - 0.22 11.4 2.4 0.52 10.2 2.4 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif zinc_ribbon_2 PF13240.6 EGO21118.1 - 9.5 6.1 8.7 28 4.6 8.7 1.8 1 0 0 1 1 1 0 zinc-ribbon domain POT1 PF02765.17 EGO21119.1 - 7e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TAP42 PF04177.12 EGO21120.1 - 7.2e-92 307.9 1.3 8.6e-92 307.7 1.3 1.0 1 0 0 1 1 1 1 TAP42-like family Ras PF00071.22 EGO21121.1 - 1.7e-58 196.8 0.2 2.4e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO21121.1 - 1.9e-37 128.1 0.1 3.2e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21121.1 - 6.4e-16 58.3 0.1 8.4e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO21121.1 - 6e-07 29.1 0.1 8.7e-07 28.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGO21121.1 - 7.5e-06 25.6 0.3 8.1e-05 22.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO21121.1 - 8.6e-06 25.3 0.4 1.1e-05 24.9 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO21121.1 - 9e-06 25.8 0.1 5.1e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO21121.1 - 0.00016 21.6 0.1 0.041 13.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGO21121.1 - 0.0016 18.0 0.3 0.097 12.2 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 EGO21121.1 - 0.039 13.4 0.1 0.2 11.0 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 EGO21121.1 - 0.039 14.0 0.1 2.4 8.2 0.0 2.7 2 1 1 3 3 3 0 Dynamin family CPT PF07931.12 EGO21121.1 - 0.064 13.1 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 EGO21121.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGO21121.1 - 0.1 12.4 1.0 0.33 10.7 1.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGO21121.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MTHFR PF02219.17 EGO21122.1 - 1.1e-107 359.6 0.0 2e-107 358.8 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TcA_TcB_BD PF18276.1 EGO21122.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Apc15p PF05841.11 EGO21123.1 - 0.0066 17.2 0.3 0.012 16.4 0.2 1.5 1 1 0 1 1 1 1 Apc15p protein ANAPC15 PF15243.6 EGO21123.1 - 0.31 11.5 16.0 1.5e+02 2.9 16.0 2.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Na_trans_assoc PF06512.13 EGO21123.1 - 0.58 10.4 6.9 0.66 10.2 6.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated LAT PF15234.6 EGO21123.1 - 1.8 8.2 8.2 2.1 8.1 7.9 1.4 1 1 0 1 1 1 0 Linker for activation of T-cells ANAPC4_WD40 PF12894.7 EGO21124.1 - 0.0033 17.7 0.0 0.83 10.0 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO21124.1 - 0.0034 18.2 24.3 0.011 16.6 0.2 7.2 8 1 0 8 8 8 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGO21124.1 - 0.015 13.8 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Transket_pyr PF02779.24 EGO21125.1 - 2e-41 141.6 0.1 2.8e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGO21125.1 - 1.9e-27 95.6 0.0 1.1e-26 93.1 0.0 2.2 2 1 0 2 2 2 1 Transketolase, C-terminal domain DUF1029 PF06269.12 EGO21126.1 - 0.056 13.6 1.4 0.12 12.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) PI3_PI4_kinase PF00454.27 EGO21128.1 - 9.7e-38 130.4 0.0 2.8e-35 122.3 0.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGO21128.1 - 3.3e-22 78.8 0.1 1.4e-21 76.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EGO21128.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RdRP PF05183.12 EGO21129.1 - 2.4e-177 591.2 0.0 2.9e-177 590.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase IFT57 PF10498.9 EGO21130.1 - 0.003 16.6 2.4 0.0037 16.3 2.4 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4972 PF16342.5 EGO21130.1 - 0.019 14.7 1.9 2.1 8.1 1.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) Peptidase_M28 PF04389.17 EGO21131.1 - 4e-36 124.6 0.0 8.9e-36 123.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 YebG PF07130.12 EGO21131.1 - 0.096 12.6 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 YebG protein Sybindin PF04099.12 EGO21132.1 - 2.7e-40 137.6 0.0 3e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGO21132.1 - 1.8e-08 34.6 0.0 1.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region TATR PF03430.13 EGO21132.1 - 0.12 10.7 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator HORMA PF02301.18 EGO21133.1 - 1.1e-44 152.6 0.0 2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PUL PF08324.11 EGO21135.1 - 2.5e-44 151.6 0.0 3.3e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGO21135.1 - 9e-43 145.1 0.1 1.9e-42 144.1 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGO21135.1 - 3.2e-31 106.9 15.6 2.9e-07 31.1 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGO21135.1 - 1.3e-07 31.6 0.1 0.0035 17.3 0.0 3.3 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGO21135.1 - 0.14 11.4 0.0 2.6 7.3 0.0 2.7 2 1 2 4 4 4 0 WD40-like domain Neocarzinostat PF00960.18 EGO21139.1 - 0.093 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Neocarzinostatin family RVP_2 PF08284.11 EGO21141.1 - 7.1e-09 35.5 0.0 7.8e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO21141.1 - 8.4e-09 35.9 0.0 9.4e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO21141.1 - 6.9e-07 29.8 0.0 7.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 EGO21141.1 - 0.0015 18.6 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon peptidase zf-CCHC PF00098.23 EGO21142.1 - 1.4e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO21142.1 - 0.0083 15.9 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO21142.1 - 0.014 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain DUF3143 PF11341.8 EGO21145.1 - 0.032 14.6 0.3 0.037 14.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) MraZ PF02381.18 EGO21145.1 - 0.078 13.0 0.1 0.098 12.6 0.1 1.1 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like TDP43_N PF18694.1 EGO21146.1 - 0.15 11.9 0.3 3.1 7.7 0.2 2.2 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DUF2633 PF11119.8 EGO21146.1 - 0.17 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) YTH PF04146.15 EGO21147.1 - 1.8e-40 138.6 0.3 5.4e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 YT521-B-like domain UPF0261 PF06792.11 EGO21148.1 - 3.1e-154 513.8 0.8 3.5e-154 513.6 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 EGO21149.1 - 2.1e-131 437.0 0.5 2.4e-131 436.8 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like AP_endonuc_2 PF01261.24 EGO21149.1 - 0.036 13.5 0.1 0.077 12.4 0.1 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel NMO PF03060.15 EGO21149.1 - 0.049 13.0 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Usp PF00582.26 EGO21149.1 - 0.15 12.6 0.3 4.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Universal stress protein family WD40 PF00400.32 EGO21150.1 - 3.7e-58 192.1 14.3 1.3e-09 38.5 0.1 8.0 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21150.1 - 8.4e-23 80.5 0.4 3.3e-06 27.3 0.1 5.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO21150.1 - 9.5e-13 47.6 0.4 0.02 13.6 0.0 5.4 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO21150.1 - 1.4e-05 24.1 0.7 1.3 7.7 0.0 4.3 1 1 4 5 5 5 3 Nup133 N terminal like Coatomer_WDAD PF04053.14 EGO21150.1 - 0.00018 20.7 0.0 0.042 12.9 0.0 2.6 2 1 1 3 3 3 2 Coatomer WD associated region eIF2A PF08662.11 EGO21150.1 - 0.00063 19.7 0.1 4.1 7.2 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGO21150.1 - 0.0019 17.2 0.1 1.8 7.5 0.0 3.7 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGO21150.1 - 0.026 13.1 0.9 4.7 5.6 0.0 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain WD40_like PF17005.5 EGO21150.1 - 0.23 10.7 0.0 31 3.7 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Kinesin PF00225.23 EGO21151.1 - 5.8e-80 268.7 0.4 3.2e-79 266.3 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGO21151.1 - 1.9e-06 27.9 0.0 5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding OmpH PF03938.14 EGO21151.1 - 0.039 14.3 2.8 0.11 12.9 2.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 EGO21151.1 - 0.089 13.2 10.4 0.72 10.3 0.6 3.6 3 0 0 3 3 3 0 Cell division protein ZapB COG5 PF10392.9 EGO21151.1 - 0.14 12.3 3.7 3.1 8.0 0.2 2.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Spectrin PF00435.21 EGO21151.1 - 0.63 10.6 6.1 0.44 11.1 0.4 2.5 2 0 0 2 2 2 0 Spectrin repeat Fez1 PF06818.15 EGO21151.1 - 0.68 10.4 12.3 3.8 7.9 2.8 2.5 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 EGO21151.1 - 1.4 9.0 3.9 2.2 8.3 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EGO21151.1 - 3.6 7.8 15.8 5.2 7.3 2.9 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EGO21151.1 - 5 6.4 10.5 3.2 7.1 0.5 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 EGO21151.1 - 5.4 7.4 7.5 2.3 8.6 1.8 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 EGO21152.1 - 3e-05 23.9 7.1 3e-05 23.9 7.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Macoilin PF09726.9 EGO21152.1 - 0.00035 19.3 14.9 0.00039 19.1 14.9 1.0 1 0 0 1 1 1 1 Macoilin family Golgin_A5 PF09787.9 EGO21152.1 - 0.0017 17.9 18.4 0.0062 16.0 10.3 2.0 1 1 1 2 2 2 2 Golgin subfamily A member 5 Med21 PF11221.8 EGO21152.1 - 0.0024 18.1 2.7 0.0024 18.1 2.7 2.3 1 1 2 3 3 3 1 Subunit 21 of Mediator complex TMF_DNA_bd PF12329.8 EGO21152.1 - 0.0026 17.7 16.8 0.009 16.0 2.7 3.1 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding CALCOCO1 PF07888.11 EGO21152.1 - 0.0033 16.4 15.8 0.0045 15.9 15.8 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 EGO21152.1 - 0.0044 16.0 15.6 0.0069 15.3 15.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 EGO21152.1 - 0.0044 16.4 14.3 0.0069 15.8 14.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EGO21152.1 - 0.0048 17.4 16.0 0.0067 16.9 16.0 1.2 1 0 0 1 1 1 1 Fez1 KASH_CCD PF14662.6 EGO21152.1 - 0.0055 16.6 14.8 0.0055 16.6 14.8 1.9 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EGO21152.1 - 0.0063 16.5 21.9 0.013 15.5 13.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 EGO21152.1 - 0.0082 16.3 16.0 0.02 15.0 16.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 EGO21152.1 - 0.0083 16.5 5.7 0.0083 16.5 5.7 2.1 1 1 1 2 2 2 1 Zinc finger-containing protein Lebercilin PF15619.6 EGO21152.1 - 0.0093 15.6 22.3 0.048 13.3 14.0 2.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EGO21152.1 - 0.011 15.8 10.4 0.51 10.4 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mce4_CUP1 PF11887.8 EGO21152.1 - 0.012 15.1 2.7 0.043 13.3 1.0 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative HIP1_clath_bdg PF16515.5 EGO21152.1 - 0.016 15.8 18.7 0.19 12.3 5.5 3.1 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FOXP-CC PF16159.5 EGO21152.1 - 0.02 15.5 4.7 0.35 11.5 0.2 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2353 PF09789.9 EGO21152.1 - 0.021 14.2 14.3 0.028 13.8 14.3 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) FliJ PF02050.16 EGO21152.1 - 0.023 14.9 16.3 0.72 10.1 9.8 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein MscS_porin PF12795.7 EGO21152.1 - 0.049 13.2 18.2 0.77 9.3 19.5 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 EGO21152.1 - 0.053 13.0 15.6 0.079 12.4 15.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GldM_N PF12081.8 EGO21152.1 - 0.057 13.5 2.2 0.073 13.2 1.2 1.7 1 1 0 1 1 1 0 GldM N-terminal domain DUF4407 PF14362.6 EGO21152.1 - 0.072 12.4 14.2 0.1 11.9 13.6 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prominin PF05478.11 EGO21152.1 - 0.079 10.9 2.9 0.086 10.8 2.9 1.2 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 EGO21152.1 - 0.087 12.9 21.9 2 8.5 21.9 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 EGO21152.1 - 0.094 12.8 12.3 0.14 12.3 3.6 2.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 EGO21152.1 - 0.096 12.2 8.6 0.16 11.5 8.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFP_35_N PF07334.13 EGO21152.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.1 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Baculo_PEP_C PF04513.12 EGO21152.1 - 0.17 12.0 5.5 0.46 10.5 3.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.12 EGO21152.1 - 0.19 11.1 5.7 11 5.4 5.8 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DHR10 PF18595.1 EGO21152.1 - 0.32 11.1 25.7 2.7 8.1 2.2 2.8 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain IFT57 PF10498.9 EGO21152.1 - 0.33 9.9 9.9 0.11 11.4 7.2 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YabA PF06156.13 EGO21152.1 - 0.39 11.4 11.0 0.15 12.7 4.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 EGO21152.1 - 0.39 10.9 21.6 0.015 15.6 10.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CorA PF01544.18 EGO21152.1 - 0.4 9.9 10.3 2.9 7.1 10.3 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_13 PF13166.6 EGO21152.1 - 0.4 9.3 10.7 0.073 11.7 6.1 1.6 1 1 0 1 1 1 0 AAA domain ADIP PF11559.8 EGO21152.1 - 0.5 10.4 16.7 0.023 14.8 8.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.8 EGO21152.1 - 0.54 9.4 10.4 0.16 11.1 4.6 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 EzrA PF06160.12 EGO21152.1 - 0.6 8.2 14.0 0.068 11.3 7.7 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4200 PF13863.6 EGO21152.1 - 0.66 10.4 22.4 1.6 9.1 12.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DLP_helical PF18709.1 EGO21152.1 - 0.85 8.8 9.9 0.22 10.7 2.6 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain FlaC_arch PF05377.11 EGO21152.1 - 0.86 10.0 8.8 5.9 7.4 0.3 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 EGO21152.1 - 0.88 9.1 19.1 0.3 10.6 10.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein FAM76 PF16046.5 EGO21152.1 - 1.1 8.6 16.6 0.46 9.8 4.8 2.0 1 1 1 2 2 2 0 FAM76 protein BST2 PF16716.5 EGO21152.1 - 1.4 9.6 16.2 0.058 14.0 2.8 3.0 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Vps54_N PF10475.9 EGO21152.1 - 1.6 7.9 8.5 0.86 8.8 2.3 2.0 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex APG6_N PF17675.1 EGO21152.1 - 2.1 8.9 20.9 8.2 7.0 20.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Muted PF14942.6 EGO21152.1 - 2.3 8.6 16.4 1.5 9.2 8.4 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Mod_r PF07200.13 EGO21152.1 - 2.4 8.2 16.2 1.3 9.1 5.5 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nup54 PF13874.6 EGO21152.1 - 2.7 8.1 18.0 10 6.2 18.0 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF641 PF04859.12 EGO21152.1 - 2.8 8.3 16.3 0.49 10.7 1.8 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) TolA_bind_tri PF16331.5 EGO21152.1 - 3.1 7.9 14.1 7 6.8 9.2 3.0 1 1 1 2 2 2 0 TolA binding protein trimerisation FUSC PF04632.12 EGO21152.1 - 3.2 6.2 6.9 4.3 5.7 6.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 EGO21152.1 - 3.5 6.8 12.6 2.7 7.2 4.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein TBCA PF02970.16 EGO21152.1 - 4.3 7.7 13.1 2.3 8.6 1.7 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A Atg14 PF10186.9 EGO21152.1 - 5 6.1 18.8 16 4.4 18.8 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4404 PF14357.6 EGO21152.1 - 5.6 7.7 12.7 0.93 10.2 3.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF2203 PF09969.9 EGO21152.1 - 6.6 7.5 14.4 7.1 7.4 0.4 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.8 EGO21152.1 - 7.6 6.9 13.5 1e+02 3.3 1.0 2.4 1 1 1 2 2 2 0 YlqD protein SlyX PF04102.12 EGO21152.1 - 8.7 7.1 12.5 2.7 8.7 2.3 3.0 1 1 1 2 2 2 0 SlyX DUF724 PF05266.14 EGO21152.1 - 9.6 6.0 15.5 1.2 9.0 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3037 PF11236.8 EGO21152.1 - 9.9 6.6 8.2 22 5.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) adh_short_C2 PF13561.6 EGO21153.1 - 2.5e-56 190.8 0.1 3.3e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO21153.1 - 1.1e-41 142.5 0.1 3.1e-41 141.0 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGO21153.1 - 1.2e-10 41.6 0.1 1.9e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO21153.1 - 0.00032 20.0 0.0 0.00041 19.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGO21153.1 - 0.00064 19.3 0.0 0.0027 17.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 EGO21153.1 - 0.098 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family DUF4259 PF14078.6 EGO21153.1 - 0.72 10.6 2.0 1.4 9.6 0.7 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4259) GATA PF00320.27 EGO21154.1 - 7.4e-15 54.3 5.9 1.4e-14 53.4 5.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EGO21154.1 - 1.3e-07 31.8 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGO21154.1 - 0.0015 18.5 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 EGO21154.1 - 0.022 14.8 0.2 0.056 13.6 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain PAS_9 PF13426.7 EGO21154.1 - 0.033 14.4 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 PAS domain DUF4428 PF14471.6 EGO21154.1 - 0.22 11.5 1.7 0.33 10.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) WD40 PF00400.32 EGO21155.1 - 1.4e-15 57.4 18.4 7.6e-05 23.4 0.1 7.1 7 2 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21155.1 - 1.6e-12 47.6 0.2 0.00014 22.1 0.0 4.2 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 EGO21155.1 - 0.00072 18.4 2.6 0.005 15.6 1.7 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EGO21155.1 - 0.0012 18.8 0.1 0.61 9.9 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DASH_Dad3 PF08656.10 EGO21156.1 - 6.1e-22 77.5 0.0 7.9e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 EGO21158.1 - 1.3e-51 175.5 0.0 1.7e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21158.1 - 2.4e-25 89.3 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO21158.1 - 1.8e-05 23.7 0.0 2.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO21158.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO21158.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ins_P5_2-kin PF06090.12 EGO21159.1 - 3.9e-83 279.7 0.0 4.4e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Pet100 PF09803.9 EGO21159.1 - 0.17 12.4 0.0 0.32 11.6 0.0 1.4 1 0 0 1 1 1 0 Pet100 Acyl-CoA_dh_1 PF00441.24 EGO21160.1 - 2.5e-40 138.1 0.3 5.9e-40 136.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO21160.1 - 2.4e-37 128.1 0.0 4.2e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGO21160.1 - 6.3e-23 80.8 0.0 1.5e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO21160.1 - 8.6e-14 52.0 0.0 2.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Arginase PF00491.21 EGO21163.1 - 5.1e-77 259.1 0.1 6e-77 258.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.21 EGO21164.1 - 2.3e-30 106.0 0.0 2.7e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II COesterase PF00135.28 EGO21166.1 - 3.8e-64 217.4 0.0 5.1e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO21166.1 - 1.9e-11 44.3 0.4 5.2e-11 42.8 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold NUDIX PF00293.28 EGO21167.1 - 3.9e-09 36.6 0.0 2.8e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain SPC25 PF06703.11 EGO21168.1 - 0.051 13.4 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) WD40 PF00400.32 EGO21170.1 - 5e-61 201.2 13.5 1.6e-09 38.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21170.1 - 5.7e-23 81.0 0.1 0.00025 21.3 0.0 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO21170.1 - 5.1e-10 39.6 0.0 1.3e-05 25.2 0.0 3.3 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO21170.1 - 1e-07 31.6 0.0 0.00044 19.7 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 EGO21170.1 - 2.5e-07 29.8 2.5 0.003 16.3 0.1 4.3 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO21170.1 - 1.6e-06 27.4 2.3 0.23 10.4 0.0 3.9 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 EGO21170.1 - 0.0015 17.6 0.1 1.7 7.6 0.1 2.6 2 1 1 3 3 3 2 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 EGO21170.1 - 0.0023 16.9 1.0 0.36 9.7 0.1 3.5 2 1 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 EGO21170.1 - 0.0073 16.2 0.3 1.1 9.2 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EGO21170.1 - 0.0095 15.0 0.2 0.17 10.9 0.0 2.4 1 1 0 2 2 2 1 Coatomer WD associated region Kelch_6 PF13964.6 EGO21170.1 - 0.033 14.5 0.2 0.69 10.3 0.1 3.0 3 0 0 3 3 3 0 Kelch motif IKI3 PF04762.12 EGO21170.1 - 0.076 11.0 0.0 0.16 9.9 0.0 1.4 1 0 0 1 1 1 0 IKI3 family PQQ_3 PF13570.6 EGO21170.1 - 0.14 12.7 0.1 32 5.2 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain NIF PF03031.18 EGO21171.1 - 1.5e-22 80.0 0.0 2.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EGO21171.1 - 0.00015 21.4 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CSN8_PSD8_EIF3K PF10075.9 EGO21172.1 - 1.2e-16 61.0 0.3 2.2e-15 56.9 0.2 2.5 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family Glyco_hydro_57 PF03065.15 EGO21172.1 - 0.0063 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF1681 PF07933.14 EGO21173.1 - 4.5e-53 178.9 0.0 5.3e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 EGO21173.1 - 0.021 13.2 0.0 0.024 12.9 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Glyco_hydro_6 PF01341.17 EGO21174.1 - 5.1e-104 348.3 1.5 6.4e-104 347.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EGO21174.1 - 4.2e-12 45.8 9.5 1.2e-11 44.3 9.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain UPF0203 PF05254.12 EGO21174.1 - 0.18 12.0 0.4 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Aminotran_5 PF00266.19 EGO21175.1 - 3.9e-94 315.6 0.0 4.7e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGO21175.1 - 3.6e-09 36.3 0.2 5.5e-09 35.7 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGO21175.1 - 4.6e-06 26.2 0.2 1.1e-05 24.9 0.2 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EGO21175.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EGO21175.1 - 0.034 12.7 0.0 0.053 12.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PilA4 PF18682.1 EGO21175.1 - 0.57 10.6 2.5 12 6.4 0.7 2.7 2 0 0 2 2 2 0 Pilin A4 RRM_1 PF00076.22 EGO21176.1 - 4.3e-28 96.9 0.0 1.8e-14 53.3 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO21176.1 - 3.1e-05 23.9 0.0 0.00075 19.4 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGO21176.1 - 0.014 15.0 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO21176.1 - 0.024 14.7 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 EGO21176.1 - 0.026 14.6 0.1 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 EGO21176.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DbpA PF03880.15 EGO21176.1 - 0.14 12.1 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain CAP_GLY PF01302.25 EGO21177.1 - 4.1e-18 65.1 0.1 8e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 EGO21177.1 - 5.8e-10 38.9 0.8 5.6e-08 32.5 0.0 2.6 1 1 2 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 EGO21177.1 - 9.2e-10 38.6 14.0 0.0045 17.4 0.6 6.0 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO21177.1 - 0.00029 20.5 15.4 0.27 11.0 2.8 5.7 1 1 5 6 6 6 3 Leucine rich repeat Ubiquitin_2 PF14560.6 EGO21177.1 - 0.033 14.7 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain LRR_6 PF13516.6 EGO21177.1 - 0.065 13.3 4.1 32 4.9 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich repeat ECH_2 PF16113.5 EGO21178.1 - 6.3e-115 384.2 0.0 8e-115 383.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGO21178.1 - 6.8e-27 94.4 0.0 5.3e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase IDO PF01231.18 EGO21180.1 - 1.1e-107 360.5 0.0 1.2e-107 360.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.10 EGO21181.1 - 4.3e-51 172.5 1.6 8.1e-50 168.4 0.4 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EGO21181.1 - 1.4e-35 121.1 0.1 1.8e-34 117.5 0.0 2.5 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EGO21181.1 - 2.4e-17 62.8 0.1 5.4e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EGO21181.1 - 9.1e-14 51.2 0.1 1.7e-12 47.2 0.1 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 EGO21181.1 - 3.1e-06 25.4 0.1 0.055 11.3 0.0 3.0 2 1 0 3 3 3 2 Family of unknown function (DUF5521) DUF4539 PF15072.6 EGO21181.1 - 0.0015 18.5 0.0 0.0049 16.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) DUF223 PF02721.14 EGO21181.1 - 0.031 14.6 0.1 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 zf-AN1 PF01428.16 EGO21181.1 - 0.34 11.1 1.1 0.72 10.1 1.1 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger F-box-like PF12937.7 EGO21182.1 - 1.6e-07 31.1 0.3 4.6e-07 29.6 0.3 1.9 1 0 0 1 1 1 1 F-box-like DivIC PF04977.15 EGO21182.1 - 0.0071 16.1 0.1 0.55 10.0 0.1 2.4 2 0 0 2 2 2 1 Septum formation initiator F-box PF00646.33 EGO21182.1 - 0.0085 15.9 0.7 1.1 9.2 0.0 3.3 3 0 0 3 3 3 1 F-box domain ArsC PF03960.15 EGO21182.1 - 0.01 15.8 0.0 6.5 6.9 0.0 3.0 2 1 0 2 2 2 0 ArsC family HNH_2 PF13391.6 EGO21182.1 - 0.11 12.6 0.2 0.88 9.8 0.0 2.4 1 1 1 2 2 2 0 HNH endonuclease Peptidase_M16_M PF16187.5 EGO21183.1 - 1.8e-82 276.8 0.8 1.8e-82 276.8 0.8 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGO21183.1 - 2.3e-31 108.8 0.0 3.3e-30 105.0 0.1 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO21183.1 - 2.7e-26 92.7 0.0 3.9e-12 46.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF3429 PF11911.8 EGO21184.1 - 1.6e-41 141.9 14.7 2.3e-41 141.5 14.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) WD40 PF00400.32 EGO21185.1 - 1.3e-18 67.0 13.9 2.2e-05 25.1 0.1 5.5 5 1 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.6 EGO21185.1 - 0.0093 16.4 0.1 11 6.6 0.1 3.7 3 0 0 3 3 3 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EGO21185.1 - 0.035 14.4 0.0 3 8.2 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SH3_9 PF14604.6 EGO21187.1 - 5.2e-14 51.8 0.0 9.1e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO21187.1 - 9.9e-09 34.7 0.0 1.8e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGO21187.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 EGO21187.1 - 0.021 15.3 0.0 0.027 14.9 0.0 1.3 1 1 0 1 1 1 0 Helically-extended SH3 domain SKIP_SNW PF02731.15 EGO21189.1 - 2.6e-72 241.7 1.4 2.6e-72 241.7 1.4 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Tim54 PF11711.8 EGO21190.1 - 1e-56 192.4 0.0 2.2e-56 191.3 0.0 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DEAD PF00270.29 EGO21191.1 - 1.5e-25 90.0 0.0 4.3e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO21191.1 - 8.5e-12 45.4 0.0 2.5e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 EGO21191.1 - 1.7e-11 43.8 0.0 9.3e-11 41.4 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 EGO21191.1 - 5.8e-05 23.4 0.1 0.00093 19.5 0.1 3.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGO21191.1 - 0.00071 19.9 0.1 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGO21191.1 - 0.0019 18.6 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO21191.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGO21191.1 - 0.0076 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein CKS PF01111.19 EGO21192.1 - 2.1e-35 120.8 0.6 2.6e-35 120.5 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16_M PF16187.5 EGO21196.1 - 1.9e-90 303.0 0.2 1.2e-89 300.3 0.0 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGO21196.1 - 3e-39 134.4 1.6 4.9e-38 130.4 0.1 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO21196.1 - 8.8e-16 58.4 0.0 2e-07 31.2 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Retrotrans_gag PF03732.17 EGO21198.1 - 1.4e-05 25.3 0.1 2.8e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein Transglut_core PF01841.19 EGO21198.1 - 0.064 13.7 0.1 0.14 12.6 0.0 1.5 2 0 0 2 2 2 0 Transglutaminase-like superfamily Lipase_GDSL_2 PF13472.6 EGO21200.1 - 6.1e-07 30.0 0.2 8.8e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO21200.1 - 3.8e-06 27.0 0.0 4.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Adap_comp_sub PF00928.21 EGO21201.1 - 4.8e-84 281.9 0.1 6.2e-84 281.5 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO21201.1 - 1.1e-06 28.7 2.5 1.8e-06 28.0 2.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGO21201.1 - 0.046 13.2 0.1 0.089 12.2 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF5618 PF18498.1 EGO21201.1 - 0.074 13.3 0.2 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) SAPS PF04499.15 EGO21202.1 - 2e-130 435.9 0.0 2.5e-130 435.5 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein TPP_enzyme_N PF02776.18 EGO21203.1 - 4.8e-55 185.8 0.1 1.4e-54 184.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGO21203.1 - 3.9e-47 159.9 0.1 1.4e-45 154.8 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO21203.1 - 1.2e-40 138.4 0.7 2.9e-40 137.2 0.3 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PAP_assoc PF03828.19 EGO21204.1 - 8.1e-17 61.2 1.6 1.3e-16 60.6 0.2 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGO21204.1 - 1.7e-09 37.8 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 EGO21204.1 - 0.0055 16.9 0.4 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta palm Polbeta PF18765.1 EGO21204.1 - 0.045 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Pro_isomerase PF00160.21 EGO21207.1 - 6.2e-51 172.8 0.0 7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGO21208.1 - 8.1e-41 137.3 28.9 2.8e-05 24.8 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EGO21208.1 - 7.2e-12 45.0 2.9 1.7e-11 43.8 2.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO21208.1 - 1.1e-09 37.9 1.6 2.1e-09 37.0 1.2 1.7 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.8 EGO21208.1 - 3.9e-08 32.4 8.5 0.021 13.5 0.1 5.3 3 1 3 6 6 6 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGO21208.1 - 1.6e-06 28.3 0.2 12 6.3 0.0 5.6 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGO21208.1 - 0.14 10.9 0.0 11 4.6 0.0 2.9 4 0 0 4 4 4 0 Nup133 N terminal like PALB2_WD40 PF16756.5 EGO21208.1 - 1.9 7.4 8.6 2.8 6.8 0.8 3.7 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 EGO21211.1 - 7.1e-18 64.6 0.2 1.3e-17 63.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO21211.1 - 8.2e-06 25.9 7.7 1.5e-05 25.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDA1_CD39 PF01150.17 EGO21215.1 - 1.2e-83 281.1 0.0 5e-68 229.7 0.0 3.0 2 1 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EGO21215.1 - 0.00067 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Radical_SAM_C PF16199.5 EGO21216.1 - 1.6e-30 104.9 0.0 3e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGO21216.1 - 2.4e-17 63.8 0.1 8.5e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGO21216.1 - 9.7e-11 41.9 0.2 2.3e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO21216.1 - 2e-06 27.8 0.0 5.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO21216.1 - 0.00078 19.8 0.1 0.0083 16.5 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO21216.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Nuc_sug_transp PF04142.15 EGO21218.1 - 2.9e-92 309.2 7.6 3.3e-91 305.7 7.6 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGO21218.1 - 0.00046 20.4 2.7 0.00046 20.4 2.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 EGO21218.1 - 0.00078 18.7 6.9 0.0019 17.5 6.9 1.6 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EGO21218.1 - 0.0012 18.3 1.6 0.0012 18.3 1.6 2.6 3 1 0 3 3 3 2 Triose-phosphate Transporter family MMM1 PF10296.9 EGO21220.1 - 1.2e-12 47.5 0.0 6.3e-08 32.0 0.0 2.5 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 AAA_12 PF13087.6 EGO21221.1 - 1.3e-27 96.8 0.0 2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGO21221.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain HOIP-UBA PF16678.5 EGO21222.1 - 0.072 13.1 0.0 0.26 11.3 0.0 1.8 1 1 0 1 1 1 0 HOIP UBA domain pair MFS_1 PF07690.16 EGO21223.1 - 2.8e-43 148.2 57.2 2.3e-42 145.2 57.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO21223.1 - 3.8e-15 55.7 8.5 3.8e-15 55.7 8.5 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGO21223.1 - 3.1e-07 29.2 18.1 4.5e-07 28.7 18.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM208_SND2 PF05620.11 EGO21223.1 - 2.2 8.0 5.2 2.1 8.1 2.6 2.3 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Y_phosphatase3 PF13350.6 EGO21227.1 - 1e-44 153.3 0.0 1.2e-44 153.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21227.1 - 7.5e-06 25.7 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGO21227.1 - 7e-05 22.5 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGO21227.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGO21227.1 - 0.054 13.3 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21227.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain CVNH PF08881.10 EGO21232.1 - 1.4e-20 73.9 2.2 1.7e-20 73.6 2.2 1.1 1 0 0 1 1 1 1 CVNH domain Y_phosphatase3 PF13350.6 EGO21234.1 - 7.4e-55 186.4 0.0 9.2e-49 166.5 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO21234.1 - 1.6e-05 24.6 0.0 2.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21234.1 - 2.2e-05 24.2 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGO21234.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21234.1 - 0.0079 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 EGO21234.1 - 0.008 16.3 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGO21235.1 - 1.8e-45 155.7 0.0 2.1e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO21235.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21235.1 - 1.9e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO21235.1 - 0.0075 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGO21235.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21235.1 - 0.03 13.3 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Metallophos PF00149.28 EGO21236.1 - 3.3e-10 40.8 0.7 6.6e-10 39.8 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO21236.1 - 6.7e-05 23.1 0.1 0.00012 22.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2709 PF10915.8 EGO21236.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) AMPKBI PF04739.15 EGO21236.1 - 0.14 12.5 0.3 20 5.6 0.0 3.1 2 1 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain tRNA_Me_trans PF03054.16 EGO21238.1 - 4.6e-113 377.6 0.0 5.2e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EGO21238.1 - 0.12 11.5 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 NAD synthase CENP-C_C PF11699.8 EGO21239.1 - 1.4e-26 92.5 0.0 2.5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EGO21239.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Pex14_N PF04695.13 EGO21239.1 - 8.7 7.0 8.6 4.5 7.9 5.1 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tyr_Deacylase PF02580.16 EGO21241.1 - 5e-55 186.0 0.1 6.2e-55 185.7 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PLDc_2 PF13091.6 EGO21242.1 - 4.4e-10 39.6 0.0 0.00067 19.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGO21242.1 - 3.8e-08 33.2 0.1 0.0063 16.6 0.1 3.0 2 0 0 2 2 2 2 Phospholipase D Active site motif zf-C3HC4_3 PF13920.6 EGO21243.1 - 9.5e-08 31.8 17.4 9.5e-08 31.8 17.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO21243.1 - 0.12 12.3 15.5 0.25 11.2 15.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cyclin_N PF00134.23 EGO21245.1 - 6.7e-09 35.6 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGO21245.1 - 4.3e-08 33.7 0.5 2.5e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin zf-C4H2 PF10146.9 EGO21246.1 - 5.3e-09 36.7 2.5 5.3e-09 36.7 2.5 1.7 2 0 0 2 2 2 1 Zinc finger-containing protein DUF3450 PF11932.8 EGO21246.1 - 0.037 13.3 2.1 0.054 12.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 EGO21246.1 - 0.069 13.2 3.0 0.12 12.4 3.0 1.4 1 0 0 1 1 1 0 Laminin Domain II RibD_C PF01872.17 EGO21247.1 - 4.1e-34 118.2 0.0 5.1e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Rad21_Rec8_N PF04825.13 EGO21248.1 - 6.2e-17 61.8 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGO21248.1 - 1.5e-06 27.4 0.0 3.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF295 PF03478.18 EGO21249.1 - 0.11 12.1 0.1 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF295) TED_complement PF07678.14 EGO21262.1 - 0.032 13.3 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain Gtr1_RagA PF04670.12 EGO21263.1 - 7.2e-87 290.6 0.3 1e-86 290.1 0.0 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO21263.1 - 1.4e-07 31.8 0.0 4.1e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21263.1 - 4.5e-07 29.5 0.8 1.5e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 EGO21263.1 - 7.8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGO21263.1 - 1.7e-05 24.9 0.0 4.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO21263.1 - 0.007 16.3 0.7 3.3 7.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGO21263.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGO21263.1 - 0.034 14.4 0.2 1.8 8.9 0.1 2.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGO21263.1 - 0.039 13.7 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EGO21263.1 - 0.043 13.5 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGO21263.1 - 0.14 12.1 0.1 6.7 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGO21263.1 - 0.14 12.5 0.2 9.9 6.6 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SOGA PF11365.8 EGO21263.1 - 0.34 12.1 2.5 2.1 9.6 0.1 2.5 3 0 0 3 3 2 0 Protein SOGA G-alpha PF00503.20 EGO21263.1 - 1.1 8.3 7.1 78 2.3 7.1 3.1 1 1 0 1 1 1 0 G-protein alpha subunit Tyrosinase PF00264.20 EGO21265.1 - 2.1e-42 145.9 0.2 3.1e-42 145.4 0.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Na_Ca_ex PF01699.24 EGO21266.1 - 1.5e-38 132.1 37.3 4.2e-23 82.0 13.1 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Septin PF00735.18 EGO21269.1 - 1.5e-115 385.3 0.8 1.7e-115 385.1 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGO21269.1 - 2.2e-08 34.2 0.2 9.2e-08 32.2 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO21269.1 - 1.2e-06 28.5 0.2 3.8e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGO21269.1 - 3.5e-06 26.7 0.5 0.00045 19.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGO21269.1 - 6.9e-06 25.5 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGO21269.1 - 0.00039 20.5 0.3 1 9.4 0.1 2.4 1 1 1 2 2 2 2 Dynamin family T2SSE PF00437.20 EGO21269.1 - 0.0014 17.8 0.1 0.0025 16.9 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 EGO21269.1 - 0.002 17.3 0.1 0.0044 16.2 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 EGO21269.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 EGO21269.1 - 0.0038 16.6 0.1 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EGO21269.1 - 0.0047 17.4 0.6 0.0081 16.7 0.5 1.7 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGO21269.1 - 0.0054 17.1 0.0 0.0089 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGO21269.1 - 0.029 13.9 0.1 0.43 10.1 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGO21269.1 - 0.041 14.2 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO21269.1 - 0.044 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EGO21269.1 - 0.065 13.3 0.2 0.46 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 EGO21269.1 - 0.071 12.2 0.4 0.23 10.5 0.1 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) PhoLip_ATPase_C PF16212.5 EGO21270.1 - 5.4e-74 249.1 30.0 9.9e-74 248.2 30.0 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO21270.1 - 1.1e-20 73.1 3.1 2.9e-20 71.7 3.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGO21270.1 - 8.3e-13 49.1 1.3 1.5e-08 35.2 0.2 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO21270.1 - 2.7e-10 40.2 0.0 1.3e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO21270.1 - 0.00016 21.5 0.3 0.0056 16.4 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO21270.1 - 0.0018 17.8 2.9 0.0029 17.1 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase VRR_NUC PF08774.11 EGO21273.1 - 1.7e-23 82.7 0.0 3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 VRR-NUC domain Sugarporin_N PF11471.8 EGO21273.1 - 0.092 12.7 0.9 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension HNH_2 PF13391.6 EGO21274.1 - 0.00074 19.6 0.1 0.0018 18.4 0.1 1.8 1 1 0 1 1 1 1 HNH endonuclease Herpes_UL73 PF03554.13 EGO21276.1 - 0.02 14.9 1.6 0.028 14.4 1.6 1.2 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein ANAPC4_WD40 PF12894.7 EGO21277.1 - 0.00022 21.5 0.0 0.12 12.7 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PRKG1_interact PF15898.5 EGO21277.1 - 0.052 14.5 0.3 0.23 12.4 0.3 2.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain WD40 PF00400.32 EGO21277.1 - 0.089 13.7 2.2 1 10.3 0.4 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.25 EGO21278.1 - 2.6e-55 187.6 0.0 3.1e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21278.1 - 7.1e-40 136.9 0.0 9.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO21278.1 - 0.00096 18.5 0.0 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGO21278.1 - 0.047 13.1 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO21278.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DEAD PF00270.29 EGO21280.1 - 2.5e-48 164.2 0.0 6.4e-48 162.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21280.1 - 2.3e-23 82.6 0.1 3.2e-22 79.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGO21280.1 - 7e-20 71.0 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGO21280.1 - 3e-06 27.3 0.5 1.6e-05 25.0 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGO21281.1 - 4.3e-48 163.8 0.0 2.3e-37 128.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO21281.1 - 7.9e-08 32.6 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO21281.1 - 0.015 15.1 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Acetyltransf_1 PF00583.25 EGO21282.1 - 2.1e-08 34.4 0.0 2.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO21282.1 - 3.3e-06 27.4 0.0 6.2e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO21282.1 - 8.9e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO21282.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGO21282.1 - 0.037 14.1 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO21282.1 - 0.045 13.8 0.2 0.12 12.4 0.2 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain IML1 PF12257.8 EGO21283.1 - 3.3e-114 380.8 0.0 4.6e-114 380.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGO21283.1 - 5.4e-16 58.4 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Astro_capsid_p PF12226.8 EGO21284.1 - 0.074 12.2 0.7 0.11 11.6 0.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF836 PF05768.14 EGO21286.1 - 2.6e-06 27.7 0.0 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-CCHC PF00098.23 EGO21286.1 - 0.00099 19.1 0.9 0.0018 18.2 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO21286.1 - 0.13 12.1 0.3 0.13 12.1 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle AAA_5 PF07728.14 EGO21287.1 - 4.7e-12 46.1 0.0 9e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGO21287.1 - 1.3e-07 31.9 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGO21287.1 - 3.1e-06 27.7 0.0 7.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO21287.1 - 3.9e-05 24.0 0.0 0.00018 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO21287.1 - 4.9e-05 23.8 0.2 0.0017 18.8 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 EGO21287.1 - 0.00019 20.5 0.0 0.00066 18.7 0.0 1.7 2 0 0 2 2 2 1 PrkA AAA domain Mg_chelatase PF01078.21 EGO21287.1 - 0.00096 18.6 0.3 0.012 15.0 0.1 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGO21287.1 - 0.0026 18.1 0.0 0.0082 16.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 EGO21287.1 - 0.011 15.9 0.1 0.04 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO21287.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGO21287.1 - 0.038 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO21287.1 - 0.041 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 EGO21287.1 - 0.049 13.0 0.0 2.3 7.6 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein NB-ARC PF00931.22 EGO21287.1 - 0.05 12.8 0.1 1.1 8.4 0.1 2.1 1 1 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 EGO21287.1 - 0.056 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGO21287.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AP-5_subunit_s1 PF15001.6 EGO21287.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 RuvB_N PF05496.12 EGO21287.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EGO21287.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SH3_1 PF00018.28 EGO21288.1 - 2.8e-07 30.0 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO21288.1 - 6.8e-07 29.1 0.1 1.7e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 EGO21288.1 - 0.2 11.9 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Pam17 PF08566.10 EGO21289.1 - 7.3e-65 217.8 0.0 9e-65 217.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ResIII PF04851.15 EGO21290.1 - 1.6e-20 73.8 0.0 3.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO21290.1 - 1.3e-19 70.6 0.0 2.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO21290.1 - 8.2e-16 58.3 0.0 2.4e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF5427 PF10310.9 EGO21291.1 - 2e-51 175.4 5.8 2.7e-47 161.8 2.9 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5427) RPN6_N PF18055.1 EGO21293.1 - 3.9e-44 149.8 1.3 3.9e-44 149.8 1.3 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGO21293.1 - 3.8e-18 65.9 0.6 1.4e-17 64.1 0.6 2.1 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 EGO21293.1 - 2e-10 40.2 0.4 5.5e-10 38.8 0.4 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 EGO21293.1 - 0.0011 18.6 0.4 0.0025 17.5 0.4 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_6 PF13174.6 EGO21293.1 - 3.2 8.6 6.4 24 5.8 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 EGO21294.1 - 1.6e-50 171.2 0.2 2.3e-50 170.7 0.2 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGO21294.1 - 1.2e-15 57.9 0.0 3e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain DUF5494 PF17598.2 EGO21294.1 - 0.074 13.2 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5494) Y_phosphatase2 PF03162.13 EGO21295.1 - 0.029 14.0 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family ABC_tran PF00005.27 EGO21296.1 - 2.2e-21 76.8 0.0 4.1e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGO21296.1 - 1.2e-07 31.4 0.1 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGO21296.1 - 1.2e-05 25.2 0.1 0.0023 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGO21296.1 - 0.00033 20.8 0.3 0.0012 19.1 0.1 2.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EGO21296.1 - 0.00038 20.3 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO21296.1 - 0.0025 18.1 0.0 0.83 9.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGO21296.1 - 0.01 16.2 3.8 0.014 15.8 0.3 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EGO21296.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGO21296.1 - 0.075 12.8 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO21296.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGO21296.1 - 0.11 12.2 0.0 2.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase zf-C2H2 PF00096.26 EGO21298.1 - 0.0026 18.1 0.0 0.0026 18.1 0.0 2.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO21298.1 - 0.0091 16.8 2.0 0.016 16.0 0.0 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger Abhydrolase_6 PF12697.7 EGO21299.1 - 0.00046 20.9 0.3 0.00046 20.9 0.3 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO21299.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Amidohydro_3 PF07969.11 EGO21300.1 - 5.5e-16 59.1 3.1 2.3e-10 40.6 0.0 3.8 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO21300.1 - 6.9e-16 58.5 0.0 1.6e-10 40.8 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family AP_endonuc_2 PF01261.24 EGO21301.1 - 1.7e-31 109.3 0.0 3.4e-31 108.3 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.25 EGO21302.1 - 1.2e-60 205.2 0.2 5.2e-60 203.1 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21302.1 - 7.1e-36 123.8 0.0 2.4e-22 79.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGO21302.1 - 4.8e-05 23.4 3.3 0.049 13.5 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO21302.1 - 7.2e-05 22.2 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO21302.1 - 0.016 14.0 10.9 0.31 9.8 0.0 3.4 3 1 0 3 3 3 0 Fungal protein kinase Prominin PF05478.11 EGO21302.1 - 4.5 5.1 5.8 6.8 4.5 5.8 1.3 1 0 0 1 1 1 0 Prominin cPLA2_C2 PF18695.1 EGO21303.1 - 0.032 14.2 0.1 7.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain Formyl_trans_N PF00551.19 EGO21305.1 - 2.6e-37 128.3 0.0 4.2e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase HLH PF00010.26 EGO21307.1 - 2.7e-11 43.3 0.7 4.7e-11 42.5 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_42M PF08532.10 EGO21308.1 - 0.042 13.3 0.0 0.044 13.3 0.0 1.0 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Plavaka PF18759.1 EGO21311.1 - 6.1e-129 429.9 0.0 8.1e-129 429.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 EGO21311.1 - 0.14 13.0 6.1 0.051 14.4 2.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1326 PF07040.11 EGO21321.1 - 0.064 13.3 6.7 0.11 12.5 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) MBOAT_2 PF13813.6 EGO21322.1 - 4.1e-13 49.4 4.9 4.1e-13 49.4 4.9 3.3 2 1 1 3 3 3 1 Membrane bound O-acyl transferase family ATP-synt_J PF04911.12 EGO21323.1 - 1.5e-23 82.1 0.3 2.1e-23 81.6 0.3 1.2 1 0 0 1 1 1 1 ATP synthase j chain DUF4419 PF14388.6 EGO21324.1 - 5.2e-96 321.6 0.0 6.1e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.6 EGO21326.1 - 3.7e-113 377.9 0.0 4.3e-113 377.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.6 EGO21327.1 - 2e-17 63.6 0.0 2.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Cbl_N PF02262.16 EGO21327.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Y_phosphatase3 PF13350.6 EGO21328.1 - 1.1e-48 166.3 0.0 1.3e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO21328.1 - 3.5e-05 23.4 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21328.1 - 0.00012 21.8 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGO21328.1 - 0.013 15.3 0.0 0.076 12.8 0.0 2.1 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21328.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Sec_GG PF07549.14 EGO21329.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Retrotrans_gag PF03732.17 EGO21332.1 - 2.6e-05 24.4 0.1 2.6e-05 24.4 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein RCDG1 PF15725.5 EGO21334.1 - 0.26 11.7 4.2 0.49 10.9 4.2 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Alpha_kinase PF02816.18 EGO21335.1 - 3.4e-12 46.9 0.2 4.6e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family Y_phosphatase3 PF13350.6 EGO21337.1 - 5.4e-38 131.3 0.0 6.1e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO21337.1 - 9.2e-06 25.3 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21337.1 - 0.00021 21.0 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGO21337.1 - 0.013 15.3 0.0 0.043 13.6 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21337.1 - 0.02 13.8 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 EGO21337.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate Clathrin PF00637.20 EGO21338.1 - 6.5e-19 68.2 1.7 1.3e-13 51.0 0.3 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 EGO21338.1 - 1.2e-11 44.6 1.9 1.3e-11 44.5 0.1 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EGO21338.1 - 1.5e-09 37.7 7.9 2.8e-09 36.9 7.9 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EGO21338.1 - 0.0019 18.0 7.5 0.0035 17.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO21338.1 - 0.09 13.1 7.9 0.17 12.2 7.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EGO21338.1 - 0.11 12.4 7.3 0.19 11.7 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.17 EGO21338.1 - 0.13 12.5 0.1 2 8.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EGO21338.1 - 0.82 10.0 7.1 1.6 9.0 7.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGO21338.1 - 4.8 7.3 7.0 10 6.2 7.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO21338.1 - 6.3 6.8 8.0 12 5.9 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COX16 PF14138.6 EGO21339.1 - 1.9e-30 105.2 0.1 2.3e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Adenylsucc_synt PF00709.21 EGO21340.1 - 2.6e-172 573.5 0.0 2.9e-172 573.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DDE_1 PF03184.19 EGO21343.1 - 2.6e-07 30.5 0.0 4.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO21343.1 - 0.0012 18.6 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease RbsD_FucU PF05025.13 EGO21344.1 - 0.021 15.2 0.5 0.043 14.2 0.5 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family ABC_membrane PF00664.23 EGO21346.1 - 6.2e-57 193.3 33.9 3.5e-30 105.6 9.8 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO21346.1 - 1.8e-49 167.8 0.1 1.3e-27 96.9 0.2 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO21346.1 - 1.5e-06 27.8 6.0 0.0002 20.8 2.2 3.5 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGO21346.1 - 3.5e-06 27.5 0.2 0.11 12.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGO21346.1 - 1.5e-05 25.1 2.6 0.03 14.4 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO21346.1 - 2.2e-05 24.4 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGO21346.1 - 0.00013 22.5 0.3 0.24 11.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 EGO21346.1 - 0.00025 20.7 0.2 0.55 9.8 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EGO21346.1 - 0.00047 19.8 1.4 0.18 11.6 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Roc PF08477.13 EGO21346.1 - 0.0022 18.2 0.8 1.6 9.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 EGO21346.1 - 0.0029 17.5 2.7 1.4 8.6 0.2 2.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGO21346.1 - 0.003 17.1 0.9 0.6 9.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EGO21346.1 - 0.006 16.3 5.0 0.94 9.2 0.4 2.8 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 EGO21346.1 - 0.0071 16.4 0.6 0.26 11.3 0.1 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGO21346.1 - 0.0074 15.6 1.5 0.81 8.9 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EGO21346.1 - 0.01 15.4 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGO21346.1 - 0.023 13.6 4.1 1.1 8.1 0.4 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 EGO21346.1 - 0.058 13.5 3.5 5.6 7.0 0.2 2.6 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 EGO21346.1 - 0.087 12.4 1.6 0.98 9.0 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 EGO21346.1 - 0.12 12.4 0.0 1.9 8.5 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit MobB PF03205.14 EGO21346.1 - 0.15 12.0 1.1 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 EGO21346.1 - 0.19 11.8 5.0 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EGO21346.1 - 0.19 12.0 6.0 8.3 6.7 0.6 3.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO21346.1 - 0.28 10.9 3.7 0.96 9.1 0.4 2.8 2 1 1 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EGO21346.1 - 0.29 10.9 3.3 44 3.8 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EGO21346.1 - 0.56 10.1 3.9 0.97 9.3 0.6 2.7 2 0 0 2 2 2 0 NACHT domain Retrotrans_gag PF03732.17 EGO21349.1 - 4.2e-08 33.4 2.6 4.7e-08 33.2 0.2 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO21349.1 - 5.5e-08 32.5 5.7 1.2e-07 31.5 5.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO21349.1 - 3.1 7.8 7.1 0.34 10.9 1.8 2.1 2 0 0 2 2 2 0 Zinc knuckle DMRL_synthase PF00885.19 EGO21350.1 - 1.8e-57 193.1 0.0 2.6e-57 192.6 0.0 1.2 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Choline_transpo PF04515.12 EGO21351.1 - 1.5e-53 182.1 2.4 1.5e-53 182.1 2.4 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter SUR7 PF06687.12 EGO21351.1 - 0.46 10.1 10.3 0.32 10.6 5.1 2.5 2 1 0 2 2 2 0 SUR7/PalI family MAPEG PF01124.18 EGO21352.1 - 3.4e-18 65.8 0.5 4.4e-18 65.4 0.5 1.1 1 0 0 1 1 1 1 MAPEG family B277 PF17623.2 EGO21352.1 - 0.0043 16.2 0.0 0.11 11.5 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function Ribosomal_L37 PF08561.10 EGO21353.1 - 4.8e-19 69.0 7.9 5.7e-16 59.1 0.2 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 WD40 PF00400.32 EGO21354.1 - 3.2 8.8 8.6 3.9 8.5 0.1 4.6 6 2 0 6 6 6 0 WD domain, G-beta repeat ADH_zinc_N PF00107.26 EGO21355.1 - 1.4e-20 73.6 1.3 2.3e-20 72.9 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO21355.1 - 2.3e-12 48.1 0.0 4.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO21355.1 - 0.00023 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 EGO21355.1 - 0.0005 19.9 0.0 0.0082 16.0 0.0 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGO21355.1 - 0.031 13.7 0.9 0.05 13.1 0.9 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Retrotrans_gag PF03732.17 EGO21357.1 - 1e-07 32.1 0.1 1e-07 32.1 0.1 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO21357.1 - 0.0017 18.4 1.1 0.0017 18.4 1.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO21360.1 - 7.7e-07 29.0 1.5 8e-07 28.9 1.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO21360.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO21360.1 - 0.01 15.3 0.7 0.016 14.6 0.7 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO21360.1 - 0.15 11.8 3.5 0.19 11.4 3.5 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Sec_GG PF07549.14 EGO21361.1 - 0.064 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif PMT PF02366.18 EGO21364.1 - 1.9e-80 270.0 19.5 1.9e-80 270.0 19.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGO21364.1 - 6.6e-58 195.6 14.5 6.6e-58 195.6 14.5 2.1 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGO21364.1 - 2.1e-26 93.0 0.6 3.3e-26 92.3 0.6 1.2 1 0 0 1 1 1 1 MIR domain RRP7 PF12923.7 EGO21365.1 - 2.1e-27 95.6 6.4 2.1e-27 95.6 6.4 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EGO21365.1 - 6.2e-10 39.1 0.9 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 EGO21365.1 - 0.00023 20.9 0.1 0.0086 15.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2428 PF10350.9 EGO21365.1 - 0.26 10.5 0.6 0.44 9.8 0.6 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Bacillus_HBL PF05791.11 EGO21366.1 - 0.077 12.8 1.0 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 EGO21366.1 - 0.19 12.0 5.2 2 8.7 3.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 EGO21366.1 - 0.87 9.3 10.6 8.2 6.2 0.1 3.7 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EGO21366.1 - 0.93 9.5 11.9 14 5.8 0.8 4.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGO21366.1 - 1.5 8.9 9.7 80 3.3 0.0 4.8 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 EGO21366.1 - 2.2 8.7 11.3 11 6.4 0.4 4.8 5 0 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin-6_N PF09177.11 EGO21366.1 - 5.3 7.7 17.6 17 6.1 0.3 5.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Hydrolase_4 PF12146.8 EGO21367.1 - 7.9e-14 51.5 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO21367.1 - 2.2e-13 50.4 0.1 5.4e-12 45.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO21367.1 - 1.3e-11 45.5 0.2 1.6e-11 45.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO21367.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EGO21367.1 - 0.016 15.0 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGO21367.1 - 0.13 11.7 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF4939 PF16297.5 EGO21368.1 - 0.00042 20.2 0.1 0.00089 19.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) TipAS PF07739.13 EGO21368.1 - 0.04 14.5 0.6 0.088 13.4 0.6 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF1690 PF07956.11 EGO21368.1 - 0.059 13.8 3.3 0.078 13.4 3.3 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DGF-1_C PF11040.8 EGO21368.1 - 0.075 13.0 2.3 0.15 12.1 1.1 2.0 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-CCHC PF00098.23 EGO21369.1 - 0.0066 16.5 1.6 0.011 15.8 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO21369.1 - 0.02 15.2 0.5 0.035 14.4 0.5 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4594 PF15266.6 EGO21369.1 - 0.11 12.8 4.1 0.19 12.1 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4594) DEAD PF00270.29 EGO21370.1 - 8.5e-45 152.7 2.2 9.2e-45 152.5 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21370.1 - 7.6e-33 113.2 0.3 1.8e-31 108.7 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO21370.1 - 6.8e-06 26.2 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGO21370.1 - 0.00051 19.8 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO21370.1 - 0.0008 19.8 3.6 0.0048 17.2 0.2 2.8 3 1 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 EGO21370.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 EGO21370.1 - 0.032 14.2 0.0 0.18 11.7 0.0 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 EGO21370.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EGO21370.1 - 0.065 13.5 2.0 0.2 11.9 0.5 2.5 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 EGO21371.1 - 4.1e-51 172.8 0.0 4.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO21371.1 - 9.1e-30 103.3 0.0 1.2e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21371.1 - 3e-12 46.4 0.0 3.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO21371.1 - 3.4e-05 23.9 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO21371.1 - 9.6e-05 22.0 0.0 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO21371.1 - 0.18 11.7 0.0 5.9 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ATP-synt_Eps PF04627.13 EGO21372.1 - 1.2e-21 76.4 3.9 1.2e-21 76.4 3.9 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain PikAIV_N PF18605.1 EGO21372.1 - 0.0017 17.9 2.9 0.0022 17.5 2.2 1.6 1 1 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Sialidase PF02973.16 EGO21373.1 - 0.0028 17.2 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Sialidase, N-terminal domain COX4 PF02936.14 EGO21374.1 - 7.9e-38 129.6 0.0 9.8e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV MRP-S34 PF16053.5 EGO21374.1 - 0.058 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 MitMem_reg PF13012.6 EGO21375.1 - 7.1e-35 119.8 1.1 1.1e-34 119.2 1.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGO21375.1 - 3.4e-29 101.2 0.0 5.7e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PALB2_WD40 PF16756.5 EGO21376.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Med25_NR-box PF11244.8 EGO21376.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.7 1 1 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Haem_degrading PF03928.14 EGO21377.1 - 2.7e-32 111.3 0.0 3.2e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading Zn_clus PF00172.18 EGO21378.1 - 1.4e-08 34.7 10.5 2.9e-08 33.7 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EGO21379.1 - 2.3e-30 104.7 0.3 8.3e-30 102.9 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO21379.1 - 2.9e-12 46.7 0.7 3.8e-09 36.6 0.0 3.0 2 1 1 3 3 3 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO21379.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 EGO21379.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Hemerythrin PF01814.23 EGO21380.1 - 0.00012 22.7 0.3 0.00019 22.0 0.3 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AMP-binding PF00501.28 EGO21383.1 - 9.5e-146 485.7 0.0 3.3e-81 273.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGO21383.1 - 4e-100 335.7 0.0 4e-52 177.4 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGO21383.1 - 3.1e-23 81.9 1.2 1.1e-08 35.3 0.1 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGO21383.1 - 2.3e-09 38.1 0.0 0.0014 19.6 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain p450 PF00067.22 EGO21384.1 - 4e-44 151.1 0.0 5.3e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SHOCT PF09851.9 EGO21384.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain SecA_SW PF07516.13 EGO21384.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 SecA Wing and Scaffold domain MFS_1 PF07690.16 EGO21385.1 - 1.4e-28 99.9 53.7 6.5e-23 81.2 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_Packaging_2 PF11123.8 EGO21385.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA packaging protein p450 PF00067.22 EGO21387.1 - 4.8e-46 157.5 0.0 6.3e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5644 PF18712.1 EGO21387.1 - 0.063 13.3 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5644) DUF382 PF04037.13 EGO21389.1 - 8.9e-59 197.2 0.2 8.9e-59 197.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EGO21389.1 - 1.8e-17 62.9 4.6 3.9e-17 61.8 4.6 1.6 1 0 0 1 1 1 1 PSP Arrestin_C PF02752.22 EGO21390.1 - 7.9e-08 32.8 0.0 2.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 EGO21390.1 - 0.00053 19.7 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 EGO21390.1 - 0.00063 19.8 0.1 0.0027 17.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PSDC PF12588.8 EGO21392.1 - 2.3e-44 150.8 0.0 3.4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EGO21392.1 - 7.1e-36 123.6 0.0 1.2e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase LigA PF07746.11 EGO21392.1 - 0.085 13.0 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Peptidase_M23 PF01551.22 EGO21392.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 RnfC_N PF13375.6 EGO21392.1 - 0.1 12.5 0.1 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HSF_DNA-bind PF00447.17 EGO21393.1 - 2.2e-33 114.7 2.0 4.2e-33 113.8 2.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding GrpB PF04229.14 EGO21393.1 - 0.03 14.5 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 GrpB protein CoaE PF01121.20 EGO21394.1 - 8.5e-63 211.2 0.0 1e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGO21394.1 - 2.8e-06 27.9 0.1 1.8e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO21394.1 - 0.0059 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGO21394.1 - 0.1 13.0 0.2 1.5 9.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain DUF3808 PF10300.9 EGO21395.1 - 4.9e-81 272.9 0.0 6.4e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EGO21395.1 - 3.8e-05 24.1 6.7 0.053 14.0 0.0 5.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO21395.1 - 0.0039 17.9 6.2 3.2 8.8 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO21395.1 - 0.022 15.0 1.3 0.048 13.9 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGO21395.1 - 0.075 13.3 8.4 4.1 7.8 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO21395.1 - 0.23 12.2 1.7 5.7 7.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HJURP_C PF12347.8 EGO21395.1 - 0.24 11.5 0.6 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat TPR_2 PF07719.17 EGO21395.1 - 0.55 10.5 12.5 1.8 8.9 0.3 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO21395.1 - 0.65 10.7 5.6 0.7 10.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Arm PF00514.23 EGO21396.1 - 8.3e-12 44.7 19.6 0.0013 18.7 0.1 9.3 12 0 0 12 12 12 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGO21396.1 - 1.7e-09 37.9 12.3 0.98 9.9 0.2 8.0 4 1 5 9 9 9 4 HEAT repeats HEAT PF02985.22 EGO21396.1 - 6.5e-08 32.2 18.1 2.4 8.7 0.0 9.5 11 0 0 11 11 11 4 HEAT repeat DUF3361 PF11841.8 EGO21396.1 - 1.3e-07 31.7 2.7 0.0027 17.6 0.0 3.9 3 1 1 4 4 4 2 Domain of unknown function (DUF3361) Adaptin_N PF01602.20 EGO21396.1 - 4e-07 29.0 12.3 0.0071 15.0 4.6 5.0 2 1 2 4 4 4 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 EGO21396.1 - 5.6e-07 29.2 4.9 0.0019 17.6 0.5 3.4 1 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EGO21396.1 - 1.1e-06 28.8 2.1 0.47 10.5 0.0 4.8 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGO21396.1 - 0.0016 18.9 24.8 0.39 11.3 0.1 7.8 7 3 0 7 7 7 3 HEAT-like repeat CLASP_N PF12348.8 EGO21396.1 - 0.015 14.8 0.1 0.55 9.7 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal COG6 PF06419.11 EGO21397.1 - 1e-137 460.0 0.0 4.3e-137 458.0 0.0 1.8 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 DOR PF14839.6 EGO21397.1 - 0.068 13.1 0.5 0.17 11.8 0.5 1.6 1 0 0 1 1 1 0 DOR family FAD_binding_3 PF01494.19 EGO21398.1 - 6.6e-84 282.1 0.0 1.6e-82 277.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO21398.1 - 5.9e-30 104.5 0.0 1.3e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EGO21398.1 - 0.00025 20.7 0.9 0.01 15.4 0.4 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO21398.1 - 0.0016 18.6 1.1 0.0039 17.4 0.1 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO21398.1 - 0.0042 16.2 0.3 0.0066 15.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO21398.1 - 0.0043 16.3 0.3 0.009 15.3 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO21398.1 - 0.0061 15.3 0.1 0.011 14.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EGO21398.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGO21398.1 - 0.032 13.6 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO21398.1 - 0.038 13.2 0.1 0.067 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO21398.1 - 0.047 12.7 0.1 0.12 11.4 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.10 EGO21398.1 - 0.055 12.5 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 EGO21398.1 - 0.13 11.0 0.4 0.27 10.0 0.0 1.7 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 EGO21398.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_23 PF13489.6 EGO21401.1 - 1.3e-06 28.3 0.0 3.2e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NUC202 PF08166.12 EGO21401.1 - 0.039 14.0 1.5 0.092 12.8 0.1 2.2 2 0 0 2 2 2 0 NUC202 domain Sugar_tr PF00083.24 EGO21402.1 - 5.2e-95 318.9 17.1 7.4e-95 318.5 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO21402.1 - 2.1e-20 73.0 55.6 1.6e-18 66.7 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4238 PF14022.6 EGO21403.1 - 0.00097 18.7 1.8 0.0013 18.4 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF4238 PF14022.6 EGO21404.1 - 0.004 16.7 0.2 0.039 13.5 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4238) ESSS PF10183.9 EGO21405.1 - 9.9e-13 48.2 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) E1_dh PF00676.20 EGO21406.1 - 3e-114 381.0 0.0 3.6e-114 380.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGO21406.1 - 0.00023 20.5 0.1 0.00048 19.4 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EGO21406.1 - 0.0038 17.0 2.4 0.0074 16.1 1.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Y_phosphatase3 PF13350.6 EGO21407.1 - 1.4e-47 162.7 0.0 2e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO21407.1 - 7.7e-05 22.3 0.0 0.00017 21.2 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21407.1 - 0.0026 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGO21407.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21407.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain AAA_lid_7 PF17867.1 EGO21409.1 - 0.066 13.4 1.1 0.18 12.0 0.5 2.1 2 1 0 2 2 2 0 Midasin AAA lid domain Cep57_CLD_2 PF14197.6 EGO21409.1 - 0.38 10.9 7.6 1 9.5 6.5 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 F-box-like PF12937.7 EGO21410.1 - 2.3e-07 30.6 0.0 0.002 17.9 0.0 2.5 2 0 0 2 2 2 2 F-box-like Abhydrolase_6 PF12697.7 EGO21411.1 - 5e-08 33.8 3.3 1.3e-07 32.4 3.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3 PF13350.6 EGO21412.1 - 8e-53 179.8 0.0 1e-52 179.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO21412.1 - 6.2e-05 22.6 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO21412.1 - 0.00038 20.1 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGO21412.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO21412.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain STE3 PF02076.15 EGO21414.1 - 7.1e-94 314.2 15.4 8.1e-94 314.1 15.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF973 PF06157.11 EGO21414.1 - 0.079 12.0 1.2 0.13 11.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Nup54 PF13874.6 EGO21415.1 - 0.023 14.8 0.1 0.023 14.8 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 NYD-SP28_assoc PF14775.6 EGO21415.1 - 0.061 13.4 1.5 0.12 12.5 1.5 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain Response_reg PF00072.24 EGO21420.1 - 2.2e-24 85.8 0.1 3.7e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Herpes_BLRF2 PF05812.12 EGO21421.1 - 0.0079 16.3 2.9 0.02 15.1 2.9 1.6 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein APG6_N PF17675.1 EGO21421.1 - 0.13 12.8 3.5 0.22 12.0 3.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Sipho_Gp157 PF05565.11 EGO21421.1 - 0.33 10.9 3.4 0.61 10.1 3.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Spc7 PF08317.11 EGO21421.1 - 0.53 9.1 5.1 0.77 8.6 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_2 PF13639.6 EGO21422.1 - 3.8e-06 27.1 5.9 3.8e-06 27.1 5.9 2.0 2 0 0 2 2 2 1 Ring finger domain PHD_2 PF13831.6 EGO21422.1 - 3.9e-05 23.1 2.3 7.4e-05 22.2 2.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EGO21422.1 - 0.0003 20.6 6.5 0.00063 19.6 6.5 1.6 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 EGO21422.1 - 0.00096 19.3 6.2 0.0034 17.5 5.1 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain SWIM PF04434.17 EGO21422.1 - 0.0015 18.1 0.5 0.0028 17.3 0.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger C1_1 PF00130.22 EGO21422.1 - 0.0033 17.3 3.2 0.0033 17.3 3.2 1.9 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EGO21422.1 - 0.0067 16.3 6.4 0.021 14.8 6.4 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 EGO21422.1 - 0.015 14.9 3.7 0.015 14.9 3.7 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RINGv PF12906.7 EGO21422.1 - 0.023 14.8 6.4 0.059 13.5 6.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 EGO21422.1 - 0.18 11.7 5.6 0.78 9.7 5.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGO21422.1 - 6.1 7.2 11.1 0.1 12.9 3.0 2.3 3 0 0 3 3 3 0 RING-like domain NAD_binding_10 PF13460.6 EGO21423.1 - 2.5e-07 30.8 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 EGO21423.1 - 4e-05 23.1 0.0 8.6e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO21423.1 - 0.015 14.8 0.0 0.04 13.5 0.0 1.8 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF4552 PF15089.6 EGO21423.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) ApbA PF02558.16 EGO21423.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PA_decarbox PF05870.11 EGO21423.1 - 0.089 12.4 0.0 0.4 10.3 0.2 1.9 2 0 0 2 2 2 0 Phenolic acid decarboxylase (PAD) Pyr_redox_3 PF13738.6 EGO21423.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SepF PF04472.12 EGO21423.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Cell division protein SepF Coa1 PF08695.10 EGO21424.1 - 3.4e-28 97.7 0.0 4.5e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_21 PF09976.9 EGO21424.1 - 0.045 13.5 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain F-box-like PF12937.7 EGO21425.1 - 0.017 15.0 0.0 0.085 12.8 0.0 2.4 2 0 0 2 2 2 0 F-box-like LSM14 PF12701.7 EGO21426.1 - 1.1e-25 89.5 0.0 2.2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EGO21426.1 - 2.5e-10 41.1 3.6 5.1e-10 40.2 3.6 1.4 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EGO21426.1 - 0.00013 22.0 0.0 0.00033 20.7 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF2058 PF09831.9 EGO21427.1 - 9.2 6.4 11.5 17 5.5 6.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Glyoxal_oxid_N PF07250.11 EGO21430.1 - 6.4e-35 120.5 0.0 1e-33 116.6 0.0 2.8 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGO21430.1 - 3.3e-22 78.6 0.0 8.8e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) CE2_N PF17996.1 EGO21430.1 - 0.0016 18.4 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Kelch_4 PF13418.6 EGO21430.1 - 0.049 13.6 0.0 18 5.4 0.0 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Trp_DMAT PF11991.8 EGO21431.1 - 3.6e-97 326.0 0.0 4.9e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Trp_DMAT PF11991.8 EGO21432.1 - 3.6e-97 326.0 0.0 4.9e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase GST_C_3 PF14497.6 EGO21434.1 - 3.5e-11 43.2 0.0 6.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO21434.1 - 0.00015 22.0 0.1 0.00098 19.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO21434.1 - 0.00017 21.8 0.0 0.00035 20.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO21434.1 - 0.0081 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO21435.1 - 2.6e-11 43.6 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO21435.1 - 9.8e-05 22.6 0.1 0.00073 19.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO21435.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO21435.1 - 0.0068 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 EGO21436.1 - 3.5e-18 66.4 0.0 7.6e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO21436.1 - 2.4e-06 27.6 0.1 0.00029 20.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO21436.1 - 0.0004 19.9 0.5 0.19 11.1 0.2 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO21436.1 - 0.00061 19.5 0.2 0.0015 18.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EGO21436.1 - 0.001 19.5 0.0 0.018 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGO21436.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGO21436.1 - 0.0025 18.4 0.1 0.0069 16.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EGO21436.1 - 0.0055 15.6 0.3 0.12 11.2 0.1 2.5 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 EGO21436.1 - 0.013 15.3 0.0 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO21436.1 - 0.031 14.7 0.1 0.13 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EGO21436.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO21436.1 - 0.074 13.3 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain B56 PF01603.20 EGO21436.1 - 0.19 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RsgA_GTPase PF03193.16 EGO21436.1 - 0.24 11.3 0.8 0.44 10.4 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase Pkinase_fungal PF17667.1 EGO21439.1 - 6.6e-24 84.4 0.0 7.8e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase OTT_1508_deam PF14441.6 EGO21440.1 - 0.051 13.6 1.5 0.14 12.2 1.5 1.7 1 0 0 1 1 1 0 OTT_1508-like deaminase Hydrophob_seed PF14547.6 EGO21440.1 - 0.13 12.5 1.1 18 5.6 0.2 2.7 2 0 0 2 2 2 0 Hydrophobic seed protein Caprin-1_dimer PF18293.1 EGO21442.1 - 0.062 13.8 0.6 0.087 13.3 0.6 1.3 1 0 0 1 1 1 0 Caprin-1 dimerization domain Imm52 PF15579.6 EGO21447.1 - 0.067 13.1 0.1 0.19 11.6 0.0 1.7 1 1 1 2 2 2 0 Immunity protein 52 DXP_synthase_N PF13292.6 EGO21447.1 - 0.085 12.0 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase RVT_1 PF00078.27 EGO21447.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_fungal PF17667.1 EGO21451.1 - 3.3e-30 105.2 0.0 4.2e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Transposase_21 PF02992.14 EGO21454.1 - 1.2e-08 34.5 0.2 1.4e-08 34.3 0.2 1.0 1 0 0 1 1 1 1 Transposase family tnp2 DUF5551 PF17705.1 EGO21456.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5551) zinc_ribbon_9 PF14369.6 EGO21456.1 - 0.2 11.9 5.2 0.38 11.0 3.5 2.1 1 1 1 2 2 2 0 zinc-ribbon UPF0565 PF10561.9 EGO21457.1 - 0.027 13.7 0.2 0.039 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ERM PF00769.19 EGO21457.1 - 0.071 12.9 18.5 0.12 12.2 18.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SepF PF04472.12 EGO21457.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein SepF RNA_pol_Rpc4 PF05132.14 EGO21457.1 - 1 9.8 6.7 1.9 8.9 6.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 IMUP PF15761.5 EGO21457.1 - 2.5 8.9 11.0 4.5 8.0 11.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein zf-CCHC PF00098.23 EGO21458.1 - 1.9e-08 34.0 4.9 3.6e-08 33.1 4.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO21458.1 - 6.1e-07 29.6 0.1 6.1e-07 29.6 0.1 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 EGO21458.1 - 0.21 11.4 1.0 0.36 10.6 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO21458.1 - 0.51 10.4 7.5 0.074 13.0 3.4 1.7 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 EGO21459.1 - 2.5e-56 191.0 0.0 3.7e-56 190.4 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21459.1 - 4e-35 121.4 0.0 3.7e-22 78.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO21459.1 - 0.0013 18.1 0.1 0.025 13.9 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGO21459.1 - 0.053 12.3 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGO21459.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 TRM PF02005.16 EGO21460.1 - 5.8e-119 397.6 0.0 7.3e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf-Mss51 PF13824.6 EGO21460.1 - 0.055 13.6 0.4 0.15 12.1 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 NAD_binding_6 PF08030.12 EGO21461.1 - 7.6e-19 68.4 0.0 2.7e-16 60.1 0.0 2.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGO21461.1 - 1.8e-17 63.6 14.9 1.8e-17 63.6 14.9 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGO21461.1 - 5.9e-12 45.6 0.0 3.5e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain HMA PF00403.26 EGO21462.1 - 8.9e-16 58.1 1.0 1e-15 57.9 1.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Tic22 PF04278.12 EGO21462.1 - 0.085 12.2 0.1 0.1 11.9 0.1 1.2 1 1 0 1 1 1 0 Tic22-like family AA_permease_2 PF13520.6 EGO21463.1 - 3.6e-63 213.9 38.4 4.5e-63 213.5 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO21463.1 - 1.8e-28 99.4 32.8 2.5e-28 98.9 32.8 1.2 1 0 0 1 1 1 1 Amino acid permease RNase_PH PF01138.21 EGO21464.1 - 1.1e-28 100.3 0.3 1.9e-28 99.6 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGO21464.1 - 0.00014 21.8 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FA_synthesis PF02504.15 EGO21464.1 - 0.038 13.0 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein DUF2040 PF09745.9 EGO21465.1 - 2e-38 131.2 24.3 2e-38 131.2 24.3 3.4 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) AKNA PF12443.8 EGO21465.1 - 0.013 16.1 0.1 0.013 16.1 0.1 2.6 3 0 0 3 3 3 0 AT-hook-containing transcription factor RRM_1 PF00076.22 EGO21466.1 - 2e-15 56.3 0.0 4.7e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO21466.1 - 9.3e-08 32.1 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EGO21466.1 - 0.0036 17.2 0.0 0.0048 16.8 0.0 1.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGO21466.1 - 0.18 11.8 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TFIID-18kDa PF02269.16 EGO21467.1 - 3e-20 72.0 0.0 4.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Mucin PF01456.17 EGO21467.1 - 5.2 7.0 18.9 9 6.3 18.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4211 PF13926.6 EGO21468.1 - 6.7e-36 123.5 0.5 3.8e-35 121.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) UNC-79 PF14776.6 EGO21469.1 - 1.5e-05 24.0 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 DPM2 PF07297.12 EGO21470.1 - 2.8e-26 91.6 1.1 3.1e-26 91.5 1.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGO21470.1 - 1.4e-05 25.0 0.6 1.5e-05 24.9 0.6 1.1 1 0 0 1 1 1 1 PIG-P TRAPPC9-Trs120 PF08626.11 EGO21471.1 - 2.1e-205 684.6 0.0 9.2e-204 679.2 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Kinesin PF00225.23 EGO21472.1 - 1.4e-110 369.3 1.5 1.9e-110 368.9 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGO21472.1 - 1.6e-24 86.5 0.0 7e-24 84.5 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding HisKA PF00512.25 EGO21472.1 - 2.8 8.0 6.8 3.4 7.8 0.3 4.0 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain Elf1 PF05129.13 EGO21473.1 - 1.4e-28 98.7 0.9 1.7e-28 98.4 0.9 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Nup96 PF12110.8 EGO21473.1 - 0.0087 15.2 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear protein 96 zf-CHY PF05495.12 EGO21473.1 - 0.0087 16.5 0.4 0.013 16.0 0.4 1.3 1 0 0 1 1 1 1 CHY zinc finger Kinesin PF00225.23 EGO21474.1 - 4.6e-112 374.2 0.1 1.5e-111 372.6 0.1 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO21474.1 - 1.6e-28 99.5 0.0 5.5e-28 97.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 EGO21474.1 - 8.3e-05 22.5 4.8 8.3e-05 22.5 4.8 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF465) DUF963 PF06131.11 EGO21474.1 - 0.71 9.4 6.8 2 7.9 6.8 1.8 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Caskin1-CID PF16600.5 EGO21475.1 - 0.16 12.6 0.3 0.47 11.1 0.3 1.8 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain PUF PF00806.19 EGO21476.1 - 2.8e-70 228.2 1.5 4e-10 38.8 0.0 8.5 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 EGO21476.1 - 0.029 14.2 0.0 2.9 7.7 0.0 3.5 3 1 0 4 4 4 0 Single Cache domain 2 Sec16_C PF12931.7 EGO21477.1 - 7.6e-59 199.8 0.0 8.7e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 OST3_OST6 PF04756.13 EGO21478.1 - 2.2e-89 299.7 0.0 2.5e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EGO21478.1 - 0.0045 17.0 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin NADH-u_ox-rdase PF10785.9 EGO21478.1 - 0.74 10.5 3.2 2 9.2 0.2 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Glyco_transf_15 PF01793.16 EGO21480.1 - 1.9e-128 428.3 3.9 2.3e-128 428.0 3.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 EGO21481.1 - 5.6e-114 380.8 11.6 6.4e-114 380.6 11.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 EGO21482.1 - 4.1e-88 295.3 3.7 4.7e-88 295.1 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.27 EGO21483.1 - 1.3e-22 80.8 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO21483.1 - 1.3e-07 31.7 0.4 0.00086 19.2 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO21483.1 - 6.3e-05 22.5 0.0 0.035 13.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO21483.1 - 0.00038 20.7 0.0 0.00064 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGO21483.1 - 0.00051 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO21483.1 - 0.0006 20.2 0.0 0.00075 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGO21483.1 - 0.0012 18.8 0.3 0.0047 16.9 0.1 1.9 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 EGO21483.1 - 0.0019 18.7 0.1 0.0029 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 EGO21483.1 - 0.0021 16.8 0.0 0.18 10.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGO21483.1 - 0.0036 17.5 0.0 0.05 13.8 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EGO21483.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGO21483.1 - 0.029 14.3 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EGO21483.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EGO21483.1 - 0.042 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGO21483.1 - 0.05 12.8 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 EGO21483.1 - 0.055 12.5 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EGO21483.1 - 0.12 12.1 0.1 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 EGO21483.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DEAD PF00270.29 EGO21483.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_14 PF13173.6 EGO21483.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.5 2 0 0 2 2 1 0 AAA domain ABC_ATPase PF09818.9 EGO21483.1 - 0.16 10.7 0.2 8.5 5.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 EGO21483.1 - 0.17 12.5 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGO21483.1 - 0.17 12.0 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 EGO21483.1 - 0.19 12.0 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGO21483.1 - 0.22 11.1 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AKNA PF12443.8 EGO21486.1 - 0.0045 17.6 0.4 0.0068 17.0 0.3 1.5 1 1 0 1 1 1 1 AT-hook-containing transcription factor TSC22 PF01166.18 EGO21486.1 - 0.061 13.6 0.2 2.2 8.6 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 EGO21486.1 - 0.078 13.4 6.0 3.5 8.1 0.3 2.6 2 1 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 EGO21486.1 - 0.66 10.1 2.8 6.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper NPV_P10 PF05531.12 EGO21486.1 - 0.94 10.0 7.3 11 6.6 7.3 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 EGO21486.1 - 5.4 6.9 7.1 2.4 8.0 1.1 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF3552 PF12072.8 EGO21487.1 - 0.0012 18.4 0.8 0.016 14.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF3915 PF13054.6 EGO21487.1 - 0.049 13.6 5.8 0.082 12.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DAGK_cat PF00781.24 EGO21489.1 - 7.2e-25 87.0 0.0 1.2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EGO21489.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Methyltransf_11 PF08241.12 EGO21490.1 - 3.6e-14 53.2 0.0 6.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO21490.1 - 1.8e-11 44.6 0.0 4.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO21490.1 - 4.8e-07 30.4 0.0 1e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO21490.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 EGO21490.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EGO21490.1 - 0.0021 17.5 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Rsm22 PF09243.10 EGO21490.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Unstab_antitox PF09720.10 EGO21490.1 - 0.063 13.3 0.1 8.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Putative addiction module component Methyltransf_31 PF13847.6 EGO21490.1 - 0.086 12.6 0.0 0.35 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EGO21490.1 - 0.09 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MaoC_dehydratas PF01575.19 EGO21491.1 - 0.00084 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Histone PF00125.24 EGO21492.1 - 1.9e-21 76.8 2.5 2.4e-21 76.5 2.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO21492.1 - 5.6e-05 23.4 0.1 5.6e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGO21492.1 - 0.00032 21.1 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGO21492.1 - 0.0026 17.8 0.1 0.0031 17.6 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein DUF1018 PF06252.12 EGO21492.1 - 0.045 14.8 0.8 0.062 14.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) PRCC PF10253.9 EGO21493.1 - 3e-30 106.6 5.7 3e-30 106.6 5.7 2.9 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting TSNAXIP1_N PF15739.5 EGO21493.1 - 0.13 12.6 1.3 0.27 11.6 1.3 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Nucleoporin_C PF03177.14 EGO21494.1 - 7.9e-85 285.8 3.5 1.1e-84 285.4 3.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EGO21494.1 - 2.6e-17 62.7 0.0 3.6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like PRIMA1 PF16101.5 EGO21495.1 - 7.2 6.7 8.8 14 5.7 8.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 WD40 PF00400.32 EGO21496.1 - 5.3e-09 36.6 4.4 0.013 16.3 0.2 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat zf-C2H2_jaz PF12171.8 EGO21497.1 - 3.8e-09 36.6 3.0 6.4e-09 35.9 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGO21497.1 - 0.029 14.7 0.1 0.048 14.0 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGO21497.1 - 0.066 13.6 1.5 0.12 12.8 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Rab_eff_C PF04698.12 EGO21497.1 - 0.17 10.1 0.0 0.21 9.9 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Swi3 PF07962.12 EGO21498.1 - 8.1e-29 99.5 0.0 1.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Telomere_reg-2 PF10193.9 EGO21499.1 - 1.6e-30 105.8 0.0 3.9e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein Spo0M PF07070.11 EGO21499.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein adh_short PF00106.25 EGO21500.1 - 2.1e-19 69.7 0.0 1.3e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO21500.1 - 7.7e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO21500.1 - 0.00038 20.4 0.1 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 KR domain Linker_histone PF00538.19 EGO21501.1 - 3e-23 82.0 0.0 3e-23 82.0 0.0 2.2 3 0 0 3 3 3 1 linker histone H1 and H5 family AMP-binding PF00501.28 EGO21502.1 - 3.5e-20 72.0 0.0 5.5e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Zn_ribbon_17 PF17120.5 EGO21503.1 - 6.1e-05 22.6 5.8 6.1e-05 22.6 5.8 3.0 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EGO21503.1 - 0.0051 17.6 21.2 0.057 14.3 3.0 5.7 6 1 0 6 6 6 2 WD domain, G-beta repeat Zf_RING PF16744.5 EGO21503.1 - 0.27 11.3 4.5 0.92 9.7 4.5 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger RXT2_N PF08595.11 EGO21503.1 - 1 9.4 3.9 0.33 11.0 0.4 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal C1_2 PF03107.16 EGO21503.1 - 1.1 9.6 10.4 1.9 8.9 8.7 2.3 1 1 0 1 1 1 0 C1 domain 2Fe-2S_thioredx PF01257.19 EGO21504.1 - 6.4e-58 194.7 0.0 8.6e-58 194.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.21 EGO21505.1 - 2.8e-41 141.8 0.0 7.8e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel TEA PF01285.18 EGO21506.1 - 1.2e-26 92.6 0.1 2.1e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 TEA/ATTS domain ERAP1_C PF11838.8 EGO21509.1 - 1.7e-72 244.7 1.4 4.3e-72 243.3 1.4 1.7 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGO21509.1 - 1.1e-60 204.9 0.2 3.8e-60 203.2 0.2 1.9 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGO21509.1 - 1.4e-48 165.6 4.4 5.9e-46 157.0 0.2 2.4 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EGO21509.1 - 0.034 14.1 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) p450 PF00067.22 EGO21510.1 - 6.1e-76 256.0 0.0 5e-59 200.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EGO21511.1 - 4.5e-63 213.6 0.0 7.1e-63 212.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Pox_MCEL PF03291.16 EGO21512.1 - 9.8e-84 281.3 0.0 1.2e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EGO21512.1 - 3.5e-12 46.9 0.0 7.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO21512.1 - 2.8e-07 30.5 0.0 4.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO21512.1 - 3.8e-07 30.8 0.0 6.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO21512.1 - 7.9e-07 29.6 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO21512.1 - 1.6e-06 28.0 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EGO21512.1 - 0.00098 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.17 EGO21512.1 - 0.0016 17.7 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 EGO21512.1 - 0.0025 17.4 0.0 0.0059 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain HECT PF00632.25 EGO21513.1 - 4e-92 309.0 0.0 5.3e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EGO21513.1 - 7e-37 125.2 19.1 2.7e-13 49.8 5.1 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EGO21513.1 - 1.1e-20 73.8 0.2 3.2e-20 72.4 0.2 1.8 1 0 0 1 1 1 1 C2 domain Sec_GG PF07549.14 EGO21514.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif NRBF2_MIT PF17169.4 EGO21518.1 - 0.00048 20.3 1.4 0.00048 20.3 1.4 2.4 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 PaREP1 PF05942.11 EGO21518.1 - 0.00052 19.9 0.4 0.00052 19.9 0.4 2.1 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DUF2383 PF09537.10 EGO21518.1 - 0.00058 20.2 5.3 0.023 15.0 0.9 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) Cnn_1N PF07989.11 EGO21518.1 - 0.11 12.7 0.4 0.11 12.7 0.4 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Pyr_redox_2 PF07992.14 EGO21518.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mog1 PF04603.12 EGO21519.1 - 4.3e-40 137.3 0.2 5.2e-40 137.0 0.2 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Spin-Ssty PF02513.17 EGO21519.1 - 0.081 12.7 0.8 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Spin/Ssty Family DUF996 PF06195.13 EGO21520.1 - 0.6 10.4 8.8 0.089 13.1 3.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF996) RNase_T PF00929.24 EGO21521.1 - 1.2e-14 55.2 0.0 6.3e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 Exonuclease CMS1 PF14617.6 EGO21522.1 - 6.2e-79 264.9 3.2 7.3e-79 264.7 3.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PEHE PF15275.6 EGO21522.1 - 0.2 12.3 4.7 0.31 11.7 4.0 1.6 1 1 0 1 1 1 0 PEHE domain PRP21_like_P PF12230.8 EGO21523.1 - 5.2e-48 163.8 10.6 5.2e-48 163.8 10.6 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGO21523.1 - 2.7e-37 126.5 1.9 6.1e-18 64.6 0.1 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EGO21523.1 - 2.3e-09 36.9 0.0 4.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 EGO21523.1 - 0.0073 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 EGO21523.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO21523.1 - 0.17 12.5 0.1 0.17 12.5 0.1 2.7 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain E7 PF00527.18 EGO21523.1 - 1.8 8.8 5.4 13 6.0 0.5 2.7 2 0 0 2 2 2 0 E7 protein, Early protein UQ_con PF00179.26 EGO21525.1 - 1.7e-19 69.8 0.0 2.3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGO21525.1 - 0.0082 16.4 0.1 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 RWD domain Rubredoxin PF00301.20 EGO21525.1 - 0.35 10.9 2.4 0.44 10.6 0.0 2.4 3 0 0 3 3 3 0 Rubredoxin CHCH PF06747.13 EGO21526.1 - 0.0001 22.4 1.0 0.00013 22.0 1.0 1.2 1 0 0 1 1 1 1 CHCH domain NYN PF01936.18 EGO21527.1 - 1.2e-07 32.3 0.0 1.3e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 NYN domain Transcrip_reg PF01709.20 EGO21528.1 - 4.9e-68 229.1 0.1 5.5e-68 229.0 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pilus_CpaD PF09476.10 EGO21528.1 - 0.054 13.2 1.5 0.95 9.2 0.6 2.2 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Sulfate_transp PF00916.20 EGO21529.1 - 2.3e-115 385.4 16.4 3e-115 385.0 16.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGO21529.1 - 3.5e-10 39.5 0.0 6.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGO21529.1 - 0.00074 19.9 14.3 0.023 15.1 2.1 2.7 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EGO21529.1 - 0.0053 17.1 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain WD40 PF00400.32 EGO21530.1 - 4.8e-30 103.1 8.7 2.5e-09 37.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21530.1 - 3.4e-08 33.7 0.0 0.015 15.6 0.0 4.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO21530.1 - 0.0039 16.2 0.0 0.037 13.0 0.0 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short_C2 PF13561.6 EGO21531.1 - 9.6e-54 182.4 0.0 1.6e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO21531.1 - 3.4e-37 127.8 0.0 4.9e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO21531.1 - 6.8e-10 39.1 0.1 1e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 KR domain CCB2_CCB4 PF11152.8 EGO21531.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 DUF296 PF03479.15 EGO21531.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain UCR_14kD PF02271.16 EGO21532.1 - 4.9e-40 135.5 0.3 5.8e-40 135.3 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.21 EGO21533.1 - 3.6e-144 479.8 0.0 4.6e-144 479.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGO21533.1 - 3.3e-43 147.4 0.0 4.1e-42 143.9 0.0 2.3 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGO21533.1 - 2.8e-14 53.1 0.0 5.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGO21533.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EGO21533.1 - 0.052 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Cmc1 PF08583.10 EGO21534.1 - 3.8e-13 49.2 3.0 4.6e-13 49.0 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EGO21534.1 - 0.007 16.1 0.8 0.011 15.4 0.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MFS_1 PF07690.16 EGO21535.1 - 1e-24 87.1 67.8 3.8e-15 55.7 36.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_63 PF03200.16 EGO21538.1 - 7.5e-163 542.8 0.4 7.1e-162 539.6 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGO21538.1 - 6e-74 248.9 0.0 2.5e-73 246.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EGO21538.1 - 5.5e-05 22.2 0.0 9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Trehalase Endonuc-HincII PF09226.11 EGO21538.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease HincII CUE PF02845.16 EGO21538.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 CUE domain Myosin_head PF00063.21 EGO21539.1 - 6.3e-241 801.3 0.0 1.3e-240 800.3 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 EGO21539.1 - 4.6e-26 91.1 1.3 4.6e-26 91.1 1.3 3.8 3 1 1 4 4 4 1 DIL domain IQ PF00612.27 EGO21539.1 - 5.3e-13 47.5 33.8 0.0031 17.1 1.4 7.4 7 0 0 7 7 6 4 IQ calmodulin-binding motif Lebercilin PF15619.6 EGO21539.1 - 0.0072 16.0 26.4 0.029 14.0 26.3 2.0 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Myosin_N PF02736.19 EGO21539.1 - 0.018 14.9 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF4795 PF16043.5 EGO21539.1 - 0.02 14.5 13.2 0.09 12.4 10.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 EGO21539.1 - 0.13 12.5 11.9 0.41 10.8 10.5 2.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EGO21539.1 - 0.17 12.4 12.6 3.6 8.1 4.0 3.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 EGO21539.1 - 0.18 10.7 26.5 0.66 8.8 9.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 EGO21539.1 - 0.18 12.4 16.2 0.034 14.8 4.5 3.8 2 1 1 3 3 3 0 SlyX TMF_DNA_bd PF12329.8 EGO21539.1 - 0.2 11.7 25.6 0.014 15.4 6.4 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 EGO21539.1 - 0.34 11.0 24.5 0.13 12.4 9.2 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EGO21539.1 - 0.78 9.1 26.2 0.71 9.2 18.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BET PF17035.5 EGO21539.1 - 0.87 9.8 3.6 12 6.1 0.1 3.5 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation APG6_N PF17675.1 EGO21539.1 - 1.2 9.7 22.1 2.3 8.8 21.2 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region IFT57 PF10498.9 EGO21539.1 - 1.5 7.7 20.3 3 6.7 7.5 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 EGO21539.1 - 2.1 8.3 15.2 4.3 7.4 2.8 2.8 1 1 1 2 2 2 0 Laminin Domain II KASH_CCD PF14662.6 EGO21539.1 - 2.8 7.7 28.2 5.2 6.8 25.5 2.7 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EGO21539.1 - 2.9 7.9 29.9 0.16 12.0 8.1 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 EGO21539.1 - 3.3 8.4 14.6 0.63 10.8 4.0 3.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec34 PF04136.15 EGO21539.1 - 6.2 6.7 12.7 1.2 9.0 4.3 2.8 1 1 1 2 2 2 0 Sec34-like family NPV_P10 PF05531.12 EGO21539.1 - 7 7.2 10.4 19 5.8 0.7 3.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EGO21539.1 - 7.2 5.1 21.8 1.4 7.5 8.9 2.2 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 EGO21539.1 - 8.8 6.7 22.1 12 6.3 7.0 2.3 1 1 1 2 2 2 0 Fez1 GCN5L1 PF06320.13 EGO21539.1 - 9 6.5 14.8 0.28 11.3 6.1 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) MscS_porin PF12795.7 EGO21539.1 - 9.4 5.7 28.9 1.4e+02 1.9 28.6 2.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain ER PF01133.17 EGO21540.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Enhancer of rudimentary Retrotrans_gag PF03732.17 EGO21541.1 - 9.5e-07 29.0 0.2 9.5e-07 29.0 0.2 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein rve PF00665.26 EGO21542.1 - 8.3e-05 22.8 0.0 0.00081 19.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO21542.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3527 PF12043.8 EGO21544.1 - 0.0011 18.6 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) YL1 PF05764.13 EGO21546.1 - 0.0069 16.5 14.4 0.0069 16.5 14.4 1.4 2 0 0 2 2 2 1 YL1 nuclear protein SR-25 PF10500.9 EGO21546.1 - 0.019 14.6 11.5 0.031 13.9 11.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGO21546.1 - 0.02 13.2 6.4 0.019 13.3 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EGO21546.1 - 0.78 9.4 17.3 1.6 8.4 17.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGO21546.1 - 2.5 6.1 15.6 3.7 5.5 15.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EGO21546.1 - 4.1 6.4 10.3 1.9 7.5 8.3 1.4 2 0 0 2 2 2 0 Pes-10 BUD22 PF09073.10 EGO21546.1 - 4.4 6.5 21.8 4.6 6.5 21.0 1.3 1 1 0 1 1 1 0 BUD22 AAA PF00004.29 EGO21547.1 - 4.8e-59 198.5 0.0 1.7e-43 148.2 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO21547.1 - 2.1e-09 37.0 0.2 1.9e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EGO21547.1 - 3.5e-06 27.1 0.1 0.029 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO21547.1 - 3.9e-06 27.4 0.2 0.01 16.2 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGO21547.1 - 2e-05 24.4 0.0 0.0044 16.8 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGO21547.1 - 2.4e-05 24.9 0.0 0.036 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EGO21547.1 - 0.00077 19.2 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGO21547.1 - 0.00079 19.3 0.0 0.65 9.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EGO21547.1 - 0.0013 18.8 0.1 0.16 12.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGO21547.1 - 0.0031 16.8 0.0 0.031 13.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 EGO21547.1 - 0.0035 17.6 0.2 0.071 13.4 0.1 2.8 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGO21547.1 - 0.0059 17.0 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 EGO21547.1 - 0.0071 16.5 0.0 0.42 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGO21547.1 - 0.0077 15.6 0.1 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGO21547.1 - 0.0086 15.6 0.0 0.042 13.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGO21547.1 - 0.009 15.8 0.0 0.048 13.4 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 EGO21547.1 - 0.018 15.2 0.0 8.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.14 EGO21547.1 - 0.021 15.0 0.0 0.09 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EGO21547.1 - 0.028 14.4 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGO21547.1 - 0.03 13.8 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EGO21547.1 - 0.048 13.6 0.4 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EGO21547.1 - 0.073 12.8 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EGO21547.1 - 0.12 12.0 0.9 0.23 11.0 0.1 1.9 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 EGO21547.1 - 0.13 11.9 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 EGO21547.1 - 0.17 12.0 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.6 EGO21547.1 - 0.18 12.0 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 EGO21547.1 - 0.21 11.3 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit DUF1938 PF09153.10 EGO21548.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) KDZ PF18758.1 EGO21549.1 - 3.3e-24 85.7 0.3 3.3e-24 85.7 0.3 1.6 1 1 1 2 2 2 1 Kyakuja-Dileera-Zisupton transposase zf-CCHC_4 PF14392.6 EGO21551.1 - 0.042 13.6 1.6 0.073 12.8 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Pap_E4 PF02711.14 EGO21551.1 - 6.4 7.8 9.1 21 6.1 0.3 2.5 2 1 0 2 2 2 0 E4 protein Sel1 PF08238.12 EGO21554.1 - 1.5e-44 149.4 28.3 4.7e-09 36.6 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat DUF4562 PF15123.6 EGO21554.1 - 0.22 11.5 0.9 3.3 7.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4562) TPR_14 PF13428.6 EGO21554.1 - 0.99 10.4 14.1 4.1 8.5 0.3 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Putative_G5P PF17426.2 EGO21557.1 - 0.091 12.9 1.3 0.15 12.2 1.3 1.3 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P Cytochrom_NNT PF03264.14 EGO21557.1 - 3.2 7.4 6.3 4.6 6.9 6.3 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region V_ATPase_I PF01496.19 EGO21557.1 - 6.7 4.5 7.4 7.7 4.3 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PGK PF00162.19 EGO21558.1 - 1.1e-143 478.7 0.1 1.3e-143 478.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Penaeidin PF05927.11 EGO21559.1 - 0.046 14.5 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Penaeidin gag_pre-integrs PF13976.6 EGO21561.1 - 3.2e-09 36.5 0.1 5.1e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 EGO21562.1 - 1.3e-14 54.0 0.1 1.9e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 EGO21562.1 - 0.034 13.9 0.9 0.06 13.1 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle JHD PF17811.1 EGO21563.1 - 4.8e-15 56.0 0.0 1.3e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 EGO21563.1 - 1.1e-08 35.5 0.5 4.7e-08 33.5 0.5 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EGO21563.1 - 1.6e-06 27.9 7.0 3.9e-06 26.7 7.0 1.7 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 EGO21563.1 - 0.00053 19.8 0.2 0.0082 15.9 0.2 2.3 1 1 0 1 1 1 1 Cupin-like domain zf-RING_9 PF13901.6 EGO21563.1 - 0.027 14.4 2.6 0.063 13.3 2.6 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SRP72 PF08492.12 EGO21563.1 - 0.06 13.8 0.1 0.06 13.8 0.1 2.1 2 0 0 2 2 2 0 SRP72 RNA-binding domain GFA PF04828.14 EGO21563.1 - 0.072 13.4 1.8 0.16 12.3 1.8 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme PHD_2 PF13831.6 EGO21563.1 - 0.25 10.9 5.0 0.57 9.8 5.0 1.6 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 EGO21563.1 - 0.64 10.2 5.8 1.5 9.0 5.8 1.7 1 0 0 1 1 1 0 PHD-finger Retrotrans_gag PF03732.17 EGO21564.1 - 9.5e-06 25.8 1.3 1.7e-05 25.0 1.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF5636 PF18686.1 EGO21564.1 - 0.078 13.2 1.5 0.9 9.7 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5636) Retrotrans_gag PF03732.17 EGO21566.1 - 4.5e-06 26.9 0.6 8.3e-06 26.0 0.6 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Bacillus_HBL PF05791.11 EGO21566.1 - 0.17 11.7 2.4 0.54 10.1 0.2 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4939 PF16297.5 EGO21567.1 - 0.004 17.0 0.1 0.008 16.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EGO21568.1 - 0.00027 20.9 1.8 0.00027 20.9 1.8 1.6 2 0 0 2 2 2 1 Zinc knuckle Acetyltransf_13 PF13880.6 EGO21569.1 - 4.5e-17 61.8 0.0 9.8e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EGO21569.1 - 3.7e-09 36.3 0.7 6.2e-09 35.5 0.7 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EGO21569.1 - 0.00032 21.0 0.0 0.0013 19.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO21569.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO21569.1 - 0.0037 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO21569.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EGO21569.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase GATase_2 PF00310.21 EGO21571.1 - 2.2e-175 583.4 0.0 3e-175 583.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGO21571.1 - 1.5e-154 514.6 0.0 2.3e-154 514.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGO21571.1 - 2.4e-112 375.0 0.0 2.7e-111 371.5 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGO21571.1 - 2.9e-87 291.2 2.5 5e-87 290.4 2.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EGO21571.1 - 1e-23 84.0 0.0 9e-23 80.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EGO21571.1 - 5.8e-22 77.6 0.1 1.1e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DAO PF01266.24 EGO21571.1 - 9.8e-10 38.5 0.3 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO21571.1 - 5.3e-09 35.8 0.1 0.0016 17.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO21571.1 - 5.6e-08 33.2 0.2 0.00012 22.6 0.1 3.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO21571.1 - 7.9e-08 32.4 0.0 3.1e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO21571.1 - 1.9e-05 23.6 0.6 4.2e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EGO21571.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMN_dh PF01070.18 EGO21571.1 - 0.0019 17.3 0.9 0.0082 15.2 1.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_binding_2 PF00890.24 EGO21571.1 - 0.0047 16.1 0.0 0.0047 16.1 0.0 2.8 3 0 0 3 3 2 1 FAD binding domain NAD_binding_7 PF13241.6 EGO21571.1 - 0.0095 16.4 1.0 1.4 9.4 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EGO21571.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO21571.1 - 0.014 14.5 0.1 1.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGO21571.1 - 0.016 14.5 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGO21571.1 - 0.022 14.1 0.1 0.022 14.1 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FMO-like PF00743.19 EGO21571.1 - 0.044 12.2 0.1 4.9 5.4 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.21 EGO21571.1 - 0.056 13.5 0.9 13 5.8 0.1 2.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.6 EGO21571.1 - 0.069 13.3 0.3 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase domain 2-Hacid_dh_C PF02826.19 EGO21571.1 - 0.11 11.8 0.0 0.5 9.7 0.0 2.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGO21571.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 EGO21571.1 - 0.17 11.1 3.9 0.046 12.9 0.2 1.9 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EGO21571.1 - 0.46 9.5 2.8 0.7 8.9 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.32 EGO21574.1 - 3.2e-40 135.4 15.1 4.1e-10 40.1 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21574.1 - 1.5e-14 54.1 3.3 0.00034 20.8 0.1 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO21574.1 - 9.9e-09 34.6 1.4 0.046 12.7 0.0 4.4 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EGO21574.1 - 2.8e-06 27.2 1.0 0.0066 16.2 0.1 3.2 1 1 2 4 4 4 3 TUP1-like enhancer of split Nup160 PF11715.8 EGO21574.1 - 6.1e-06 25.2 2.3 0.34 9.5 0.1 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO21574.1 - 0.0016 17.3 2.0 0.06 12.1 0.8 3.6 1 1 2 3 3 3 1 Nup133 N terminal like PALB2_WD40 PF16756.5 EGO21574.1 - 0.0051 15.8 0.1 0.0051 15.8 0.1 2.4 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EGO21574.1 - 0.052 11.9 0.0 0.15 10.4 0.0 1.5 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz XRN1_D2_D3 PF18334.1 EGO21575.1 - 0.039 14.2 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D2/D3 domain CHORD PF04968.12 EGO21576.1 - 3e-42 143.1 11.1 1.7e-26 92.7 3.0 2.8 2 1 0 2 2 2 2 CHORD CS PF04969.16 EGO21576.1 - 2.6e-06 28.3 0.1 8.8e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 CS domain GTP_EFTU PF00009.27 EGO21577.1 - 1.4e-34 119.3 3.4 6.7e-33 113.9 3.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGO21577.1 - 6.4e-28 97.0 0.8 6.4e-28 97.0 0.8 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGO21577.1 - 6.6e-07 29.4 0.3 2e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGO21577.1 - 0.00024 20.9 0.6 0.012 15.3 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.6 EGO21577.1 - 0.0003 20.6 4.2 0.3 11.0 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 4 Arf PF00025.21 EGO21577.1 - 0.0018 17.7 0.1 0.0055 16.2 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EGO21577.1 - 0.0058 16.2 2.9 0.024 14.2 0.6 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO21577.1 - 0.0096 15.8 1.1 0.085 12.7 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase AAA_26 PF13500.6 EGO21577.1 - 0.046 13.5 0.3 0.091 12.6 0.3 1.5 1 0 0 1 1 1 0 AAA domain IF2_N PF04760.15 EGO21578.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Scramblase PF03803.15 EGO21579.1 - 7.4e-54 182.4 0.0 2.4e-53 180.7 0.0 1.7 1 1 0 1 1 1 1 Scramblase CDC45 PF02724.14 EGO21580.1 - 7.4e-224 744.8 0.0 8.9e-224 744.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein HAGH_C PF16123.5 EGO21581.1 - 7.4e-21 74.5 0.0 1.6e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGO21581.1 - 1.7e-08 34.7 1.6 3.7e-08 33.6 1.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO21581.1 - 0.03 13.9 0.0 0.075 12.5 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Phage_Coat_B PF05356.11 EGO21582.1 - 0.075 12.9 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Phage Coat protein B SSP160 PF06933.11 EGO21582.1 - 1.6 6.8 18.5 1.9 6.6 18.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGO21582.1 - 2 8.4 23.5 3 7.8 23.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FAM117 PF15388.6 EGO21582.1 - 2.3 7.6 11.3 3.1 7.2 11.3 1.1 1 0 0 1 1 1 0 Protein Family FAM117 PTP_tm PF18861.1 EGO21582.1 - 5.4 7.0 7.2 58 3.6 7.1 2.0 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SRP-alpha_N PF04086.13 EGO21583.1 - 1.2e-50 173.1 6.1 7.3e-49 167.2 6.1 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EGO21583.1 - 3.3e-47 160.7 0.2 1.5e-46 158.5 0.2 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EGO21583.1 - 6.6e-10 39.1 0.0 2.4e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EGO21583.1 - 7.2e-06 25.2 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EGO21583.1 - 0.0015 18.3 0.0 0.051 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO21583.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGO21583.1 - 0.0025 17.7 0.0 0.0025 17.7 0.0 1.9 3 0 0 3 3 3 1 NTPase CbiA PF01656.23 EGO21583.1 - 0.0087 16.1 0.0 0.027 14.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGO21583.1 - 0.009 15.9 0.3 0.51 10.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain ArsA_ATPase PF02374.15 EGO21583.1 - 0.01 15.1 0.4 1.3 8.2 0.1 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.18 EGO21583.1 - 0.027 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EGO21583.1 - 0.068 13.5 0.0 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EGO21583.1 - 0.11 12.5 0.7 1.2 9.3 0.5 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Cyclin_N PF00134.23 EGO21584.1 - 1.1e-09 38.1 0.0 6.8e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGO21584.1 - 0.063 13.7 0.1 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain SOR_SNZ PF01680.17 EGO21586.1 - 5.9e-112 372.4 5.8 8e-112 372.0 5.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGO21586.1 - 2.4e-09 36.9 3.6 5.2e-07 29.2 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGO21586.1 - 1.2e-05 24.6 0.2 0.094 11.8 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EGO21586.1 - 0.0014 18.6 0.0 0.0038 17.3 0.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 EGO21586.1 - 0.0034 16.6 0.2 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EGO21586.1 - 0.0041 16.6 0.4 0.53 9.7 0.0 3.0 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.15 EGO21586.1 - 0.007 15.8 5.2 0.088 12.2 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 EGO21586.1 - 0.02 14.1 0.1 0.56 9.3 0.0 2.6 2 1 0 3 3 3 0 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 EGO21586.1 - 0.021 13.9 0.4 0.038 13.0 0.0 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Img2 PF05046.14 EGO21587.1 - 1.3e-21 76.6 0.0 1.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.17 EGO21589.1 - 2.8e-44 151.6 0.0 3.2e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Ras PF00071.22 EGO21590.1 - 2.7e-65 218.9 1.2 3.1e-65 218.7 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO21590.1 - 1.4e-36 125.4 0.1 2.2e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21590.1 - 3.1e-17 62.6 0.2 3.8e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGO21590.1 - 1.8e-07 31.2 1.2 0.0018 18.2 0.3 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGO21590.1 - 4.1e-06 26.5 0.4 1.1e-05 25.1 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO21590.1 - 1.1e-05 24.9 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO21590.1 - 1.2e-05 24.8 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGO21590.1 - 3.1e-05 24.0 0.1 5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EGO21590.1 - 0.0035 17.8 0.1 0.52 10.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO21590.1 - 0.0059 17.0 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGO21590.1 - 0.0073 15.8 0.2 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region FeoB_N PF02421.18 EGO21590.1 - 0.0096 15.5 0.1 0.044 13.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 EGO21590.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EGO21590.1 - 0.042 13.8 0.0 0.085 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO21590.1 - 0.044 14.0 0.0 0.067 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EGO21590.1 - 0.071 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 EGO21590.1 - 0.074 13.6 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EGO21590.1 - 0.078 12.4 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Asp PF00026.23 EGO21591.1 - 1.1e-44 153.1 0.2 1.4e-44 152.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO21591.1 - 0.00016 22.0 2.1 0.01 16.1 2.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO21591.1 - 0.046 14.4 0.2 2.1 9.0 0.1 3.3 3 1 0 3 3 3 0 Aspartyl protease zinc_ribbon_15 PF17032.5 EGO21592.1 - 3e-06 27.9 0.1 4.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon family DUF3716 PF12511.8 EGO21592.1 - 0.022 14.8 0.5 0.036 14.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.7 EGO21592.1 - 0.023 14.7 2.0 0.07 13.1 2.0 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain HAD_2 PF13419.6 EGO21593.1 - 2.5e-06 27.7 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO21593.1 - 0.0061 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EGO21593.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Nop16 PF09420.10 EGO21594.1 - 5.6e-49 167.0 1.5 7.2e-49 166.7 1.5 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zn_clus PF00172.18 EGO21595.1 - 0.018 15.2 0.8 0.039 14.1 0.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_7 PF13499.6 EGO21596.1 - 2.4e-22 79.2 0.0 5.3e-10 39.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGO21596.1 - 2.9e-22 76.5 3.5 3.3e-05 23.1 0.0 5.2 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGO21596.1 - 3.5e-21 73.2 1.0 2.8e-05 23.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGO21596.1 - 4e-16 58.6 0.9 7e-08 32.2 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGO21596.1 - 1.2e-15 56.2 2.4 0.0052 16.2 0.0 4.8 4 1 0 4 4 4 4 EF hand DUF2333 PF10095.9 EGO21596.1 - 0.023 13.7 0.0 0.056 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) EF-hand_10 PF14788.6 EGO21596.1 - 0.029 14.2 0.0 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 EGO21596.1 - 0.054 13.5 1.2 0.63 10.0 0.5 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand HHV-5_US34A PF17087.5 EGO21596.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus US34A protein family Caleosin PF05042.13 EGO21596.1 - 0.074 13.0 0.1 2.1 8.2 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein Lambda_tail_I PF06805.12 EGO21596.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I 2OG-FeII_Oxy_2 PF13532.6 EGO21597.1 - 1.1e-23 84.5 0.0 1.3e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA PF00627.31 EGO21598.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_M24 PF00557.24 EGO21599.1 - 6.1e-44 150.2 0.1 8.2e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGO21599.1 - 0.0064 17.1 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain MFS_1 PF07690.16 EGO21601.1 - 6.3e-30 104.3 24.6 6.3e-30 104.3 24.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 EGO21602.1 - 6.7e-71 239.1 0.1 9.2e-70 235.3 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO21602.1 - 0.0017 19.3 0.1 0.0043 18.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_cc PF11790.8 EGO21603.1 - 5.6e-62 209.4 1.5 7.1e-62 209.1 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 EGO21604.1 - 2.9e-70 236.5 1.9 3.4e-70 236.3 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1996 PF09362.10 EGO21605.1 - 2e-83 280.0 2.1 2.5e-83 279.7 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-Mss51 PF13824.6 EGO21606.1 - 1.6e-24 85.7 2.5 3e-24 84.9 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.11 EGO21606.1 - 0.051 13.5 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Peptidase_M13_N PF05649.13 EGO21607.1 - 5.2e-102 342.4 0.0 6.8e-102 342.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EGO21607.1 - 1.9e-63 213.8 0.0 3.3e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Piwi PF02171.17 EGO21608.1 - 4.2e-81 272.5 0.0 5.7e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGO21608.1 - 3.9e-14 53.4 0.0 1e-13 52.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGO21608.1 - 1.6e-13 50.1 0.0 5.5e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EGO21608.1 - 6.8e-13 48.7 0.0 2.6e-12 46.9 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EGO21608.1 - 3.5e-10 40.0 0.0 2.8e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Mid domain of argonaute VASP_tetra PF08776.11 EGO21609.1 - 0.014 14.9 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain DUF445 PF04286.12 EGO21609.1 - 0.46 10.2 7.7 0.8 9.5 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DSPc PF00782.20 EGO21610.1 - 1.1e-19 70.6 0.2 1.3e-18 67.1 0.2 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO21610.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Sugar_tr PF00083.24 EGO21612.1 - 7.3e-102 341.5 22.6 8.4e-102 341.3 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO21612.1 - 6.1e-28 97.7 27.0 4.8e-27 94.8 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGO21612.1 - 6.8e-05 21.3 3.0 6.8e-05 21.3 3.0 2.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 EGO21612.1 - 0.00041 18.9 3.3 0.00064 18.3 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1837 PF08878.11 EGO21612.1 - 0.11 12.3 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) PPR PF01535.20 EGO21612.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 PPR repeat EMP70 PF02990.16 EGO21612.1 - 5 5.7 11.3 2.8 6.5 3.7 2.4 1 1 1 2 2 2 0 Endomembrane protein 70 PRTase_2 PF15609.6 EGO21613.1 - 0.09 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase PPTA PF01239.22 EGO21614.1 - 1.1e-48 161.7 13.7 2e-10 40.0 0.1 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Telomere_reg-2 PF10193.9 EGO21614.1 - 0.14 12.6 1.1 2.2 8.7 0.1 2.7 3 0 0 3 3 3 0 Telomere length regulation protein TPR_14 PF13428.6 EGO21615.1 - 7e-09 35.8 22.6 12 7.0 0.0 11.8 11 2 2 13 13 13 1 Tetratricopeptide repeat Suf PF05843.14 EGO21615.1 - 0.00015 21.8 8.8 0.055 13.5 0.2 4.9 3 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EGO21615.1 - 0.0041 17.2 6.4 72 4.0 0.1 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EGO21615.1 - 0.0043 16.2 12.0 0.32 10.1 0.0 4.9 4 3 3 7 7 7 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 EGO21615.1 - 0.0045 17.3 10.5 1.7 9.0 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO21615.1 - 0.011 16.3 10.9 0.5 10.9 0.1 5.6 6 1 0 6 6 4 0 Tetratricopeptide repeat HAT PF02184.16 EGO21615.1 - 0.032 14.2 3.5 3 7.9 0.0 5.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat Mad3_BUB1_I PF08311.12 EGO21615.1 - 0.043 13.8 11.4 5.7 6.9 0.3 6.4 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGO21615.1 - 0.08 13.1 22.7 3 8.2 0.1 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat 4HB_MCP_1 PF12729.7 EGO21615.1 - 0.24 10.9 3.5 3.8 7.0 0.1 2.6 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction TPR_10 PF13374.6 EGO21615.1 - 0.78 9.7 6.6 1.8e+02 2.2 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO21615.1 - 1 9.3 5.1 53 3.9 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 EGO21616.1 - 1.3e-16 60.7 12.7 5.9e-07 30.1 0.1 6.5 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21616.1 - 0.0011 19.3 0.1 2.3 8.6 0.0 4.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGO21616.1 - 0.077 11.7 0.6 2.1 7.0 0.6 2.7 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.8 EGO21616.1 - 0.11 11.1 1.0 0.98 8.0 0.1 2.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF3445 PF11927.8 EGO21617.1 - 3.1e-52 177.5 0.0 3.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NMO PF03060.15 EGO21618.1 - 4e-53 180.9 1.1 6e-53 180.4 1.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO21618.1 - 1.6e-10 40.6 0.1 8.3e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO21618.1 - 0.00019 20.6 2.2 0.00033 19.8 2.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyto_heme_lyase PF01265.17 EGO21619.1 - 1.3e-47 162.8 3.8 8e-46 156.9 3.8 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase APH PF01636.23 EGO21620.1 - 3e-06 27.3 0.2 4.3e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGO21620.1 - 2.6e-05 23.7 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGO21620.1 - 0.0014 18.3 0.0 0.0039 16.8 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGO21620.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EGO21620.1 - 0.031 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGO21621.1 - 4.1e-66 223.0 0.0 5.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21621.1 - 3.4e-29 101.9 0.0 4.5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO21621.1 - 0.00035 20.0 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGO21621.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MAT1 PF06391.13 EGO21622.1 - 2.6e-54 184.2 14.7 3.2e-54 183.9 14.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EGO21622.1 - 1.7e-22 79.0 7.2 2.8e-22 78.4 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO21622.1 - 5.2e-06 26.2 4.9 9.5e-06 25.4 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO21622.1 - 1.8e-05 24.6 7.1 6.4e-05 22.8 7.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGO21622.1 - 5.5e-05 23.4 7.1 9.1e-05 22.7 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO21622.1 - 8.3e-05 22.3 7.7 0.00017 21.3 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO21622.1 - 8.4e-05 22.4 5.7 0.00019 21.2 5.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO21622.1 - 0.0052 16.8 6.8 0.0055 16.7 2.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO21622.1 - 0.02 14.7 10.0 0.38 10.6 10.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGO21622.1 - 0.025 14.3 3.4 0.21 11.4 1.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGO21622.1 - 0.049 13.9 2.4 0.1 12.9 2.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain YdjO PF14169.6 EGO21622.1 - 0.078 12.7 1.4 4.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Cold-inducible protein YdjO PPL4 PF18188.1 EGO21622.1 - 0.1 12.5 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Prim-pol 4 zf-C3HC4_4 PF15227.6 EGO21622.1 - 0.66 10.2 6.8 18 5.6 8.1 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF3797 PF12677.7 EGO21622.1 - 9.8 6.2 7.6 0.22 11.4 0.8 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF3797) Proteasome PF00227.26 EGO21623.1 - 1.5e-59 200.7 0.0 2.1e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO21623.1 - 2.6e-14 52.5 0.3 1.1e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.13 EGO21624.1 - 5.7e-43 146.9 0.0 1.2e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C78 Sec7 PF01369.20 EGO21625.1 - 8.5e-66 221.1 0.1 1.8e-65 220.0 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGO21625.1 - 2.3e-19 69.8 0.0 2.2e-18 66.7 0.0 2.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGO21625.1 - 0.0019 18.0 1.3 0.87 9.5 0.1 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) Epimerase PF01370.21 EGO21626.1 - 0.022 14.3 0.1 0.048 13.1 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4050 PF13259.6 EGO21626.1 - 0.17 12.2 0.6 0.51 10.6 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) NAD_binding_2 PF03446.15 EGO21627.1 - 8.6e-37 126.7 0.4 1.2e-36 126.3 0.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGO21627.1 - 7.2e-28 97.3 0.0 1.5e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGO21627.1 - 0.012 16.2 0.0 0.031 14.8 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DEAD PF00270.29 EGO21629.1 - 1.5e-21 76.9 0.0 2.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21629.1 - 2.8e-15 56.6 0.1 9.6e-13 48.5 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGO21629.1 - 1.3e-14 54.7 0.8 3.9e-14 53.2 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.15 EGO21629.1 - 1.8e-07 31.3 0.0 4.5e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RhoGAP-FF1 PF16512.5 EGO21629.1 - 0.18 12.5 0.0 0.39 11.4 0.0 1.5 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Ku_C PF03730.14 EGO21630.1 - 0.019 15.7 0.3 0.023 15.4 0.3 1.2 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm Abhydrolase_1 PF00561.20 EGO21631.1 - 7.8e-17 61.8 0.8 6.1e-16 58.8 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO21631.1 - 3.3e-11 42.9 0.0 4.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO21631.1 - 1.9e-08 35.2 0.0 2.4e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EGO21631.1 - 0.00057 19.9 0.0 0.0075 16.2 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 EGO21631.1 - 0.037 13.1 0.2 0.14 11.2 0.1 1.8 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_3 PF07859.13 EGO21631.1 - 0.063 13.1 0.0 0.65 9.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EGO21631.1 - 0.087 12.4 0.0 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 EGO21631.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain zf-AN1 PF01428.16 EGO21632.1 - 2e-15 56.6 21.0 4.1e-08 33.2 7.3 2.5 2 1 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EGO21632.1 - 8.5 6.7 15.4 0.16 12.2 3.7 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain COG4 PF08318.12 EGO21633.1 - 1e-82 278.0 0.6 1.3e-82 277.5 0.6 1.2 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 EGO21633.1 - 0.04 12.8 0.5 0.16 10.8 0.0 2.2 3 0 0 3 3 3 0 RINT-1 / TIP-1 family TMEM95 PF15203.6 EGO21633.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 TMEM95 family Snf7 PF03357.21 EGO21634.1 - 7.3e-06 25.7 0.8 7.6e-06 25.6 0.8 1.1 1 0 0 1 1 1 1 Snf7 DUF2203 PF09969.9 EGO21634.1 - 0.021 15.6 0.2 0.022 15.5 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 EGO21634.1 - 0.036 14.1 0.4 0.038 14.1 0.4 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HTH_6 PF01418.17 EGO21634.1 - 0.054 13.5 1.1 0.27 11.2 0.5 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family DUF2229 PF09989.9 EGO21634.1 - 0.15 11.7 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-CCHC_3 PF13917.6 EGO21637.1 - 8.5e-07 28.8 1.7 8.9e-07 28.8 1.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO21637.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO21637.1 - 0.0085 15.6 1.1 0.013 14.9 1.1 1.5 1 1 0 1 1 1 1 Copper fist DNA binding domain PDGF PF00341.17 EGO21637.1 - 0.03 14.6 0.5 0.037 14.3 0.5 1.1 1 0 0 1 1 1 0 PDGF/VEGF domain zf-CCHC_5 PF14787.6 EGO21637.1 - 0.13 12.0 3.4 0.17 11.6 3.4 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Fungal_trans PF04082.18 EGO21638.1 - 4.2e-09 35.8 0.3 9.1e-09 34.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO21638.1 - 1.8e-05 24.8 12.2 3.5e-05 23.8 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RRN7 PF11781.8 EGO21638.1 - 0.15 11.7 3.2 0.35 10.6 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 WD40 PF00400.32 EGO21640.1 - 0.0025 18.6 2.9 0.05 14.5 0.2 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat DnaJ_C PF01556.18 EGO21641.1 - 5.7e-40 136.8 0.4 7.8e-40 136.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO21641.1 - 6.7e-21 74.2 0.6 1.1e-20 73.5 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO21641.1 - 1.8e-16 60.3 18.6 3.1e-16 59.5 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGO21641.1 - 0.00069 19.5 12.9 0.0085 16.0 2.1 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGO21641.1 - 2.7 8.0 10.7 4.8 7.2 2.3 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mis14 PF08641.12 EGO21642.1 - 0.0095 16.3 0.4 0.028 14.7 0.1 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like ADK PF00406.22 EGO21643.1 - 3.8e-44 150.4 0.1 6.4e-44 149.7 0.1 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGO21643.1 - 4e-30 105.0 0.0 6.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO21643.1 - 9.8e-08 32.6 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO21643.1 - 0.00024 21.3 0.0 0.003 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGO21643.1 - 0.024 14.3 0.7 0.58 9.8 0.2 2.1 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 EGO21643.1 - 0.062 13.0 0.3 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Ploopntkinase3 PF18751.1 EGO21643.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DAGK_cat PF00781.24 EGO21644.1 - 2.4e-15 56.2 0.0 3.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SDA1 PF05285.12 EGO21645.1 - 2.2e-84 283.9 35.1 7.6e-45 153.8 9.6 3.1 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 EGO21645.1 - 8.4e-25 86.9 0.4 2e-24 85.6 0.1 1.9 2 0 0 2 2 2 1 NUC130/3NT domain GalP_UDP_transf PF01087.22 EGO21646.1 - 7.1e-62 209.1 0.0 1.1e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EGO21646.1 - 3.7e-48 163.4 0.0 6.6e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EGO21646.1 - 0.0076 17.0 0.3 0.051 14.3 0.3 2.2 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO21646.1 - 0.089 13.3 1.3 0.41 11.1 1.3 2.0 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Glyco_hydro_3_C PF01915.22 EGO21647.1 - 6.8e-63 212.3 0.0 1.1e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO21647.1 - 2e-46 158.8 0.0 4.1e-46 157.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO21647.1 - 1.4e-22 79.6 0.0 2.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EGO21647.1 - 5.4e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EGO21647.1 - 0.024 15.0 0.0 0.088 13.2 0.0 2.0 1 0 0 1 1 1 0 GLEYA domain DUF748 PF05359.11 EGO21647.1 - 0.044 14.0 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) PIG-S PF10510.9 EGO21647.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Pkinase_Tyr PF07714.17 EGO21648.1 - 1.3e-39 136.1 0.0 2.3e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO21648.1 - 1.8e-35 122.6 0.0 9e-35 120.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain MCD PF05292.11 EGO21648.1 - 0.0064 16.1 0.3 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain Kinase-like PF14531.6 EGO21648.1 - 0.04 13.2 0.0 0.095 12.0 0.0 1.7 1 0 0 1 1 1 0 Kinase-like ING PF12998.7 EGO21649.1 - 6.6e-11 42.7 0.1 3.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGO21649.1 - 8.8e-06 25.5 8.3 1.4e-05 24.9 8.3 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGO21649.1 - 0.0013 18.2 2.1 0.0022 17.5 2.1 1.4 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 EGO21649.1 - 0.087 13.0 1.2 0.15 12.2 1.2 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain DHR10 PF18595.1 EGO21650.1 - 2.7e-32 111.3 23.9 2.7e-32 111.3 23.9 3.9 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain Nuf2 PF03800.14 EGO21650.1 - 4.8e-31 107.7 0.0 4.8e-31 107.7 0.0 2.5 3 1 0 3 3 3 1 Nuf2 family DUF3450 PF11932.8 EGO21650.1 - 0.0044 16.4 14.1 0.0044 16.4 14.1 3.2 1 1 1 3 3 3 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 EGO21650.1 - 0.36 11.4 51.0 2.5 8.6 5.1 4.0 2 2 1 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 EGO21650.1 - 1 8.7 46.0 0.67 9.3 14.5 3.2 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding PTH2 PF01981.16 EGO21650.1 - 3.8 7.8 7.7 2.4 8.5 4.3 2.4 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 YabA PF06156.13 EGO21650.1 - 10 6.9 32.8 1.1 10.0 0.3 4.5 1 1 3 4 4 4 0 Initiation control protein YabA DEAD PF00270.29 EGO21651.1 - 7e-22 78.0 0.0 1.4e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21651.1 - 4.4e-18 65.7 0.0 1.3e-17 64.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 EGO21651.1 - 1.2e-15 57.3 0.0 2.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EGO21651.1 - 7.4e-13 49.0 4.1 7.4e-13 49.0 4.1 2.0 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EGO21651.1 - 9.8e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO21652.1 - 2.6e-44 151.1 0.0 8.9e-44 149.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21652.1 - 2.4e-27 95.5 0.0 1.6e-26 92.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO21652.1 - 8.9e-06 25.8 0.0 0.00022 21.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGO21652.1 - 0.027 13.8 6.0 1.4 8.2 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EGO21652.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase SAM_DrpA PF18255.1 EGO21652.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain DDE_1 PF03184.19 EGO21653.1 - 6.8e-11 42.1 0.3 7.9e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Zn_clus PF00172.18 EGO21656.1 - 0.00045 20.3 16.6 0.00065 19.8 16.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.22 EGO21658.1 - 9e-47 160.2 0.0 1.4e-46 159.6 0.0 1.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 EGO21659.1 - 2.8e-53 181.0 0.0 3.5e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21659.1 - 2.3e-18 66.4 0.6 3.4e-18 65.9 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGO21659.1 - 0.0027 17.7 0.1 0.0047 16.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO21659.1 - 0.014 15.0 0.2 0.049 13.2 0.2 1.9 1 1 1 2 2 2 0 RIO1 family ABC1 PF03109.16 EGO21659.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Transferase PF02458.15 EGO21661.1 - 0.00016 20.5 0.0 0.00018 20.3 0.0 1.0 1 0 0 1 1 1 1 Transferase family IPPT PF01715.17 EGO21662.1 - 9.7e-56 189.1 0.0 2.9e-55 187.6 0.0 1.6 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 EGO21662.1 - 7.5e-05 23.3 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGO21662.1 - 0.0091 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO21662.1 - 0.022 15.0 0.1 1.4 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGO21662.1 - 0.057 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EGO21662.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 EGO21662.1 - 0.084 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PRP38 PF03371.15 EGO21665.1 - 1.5e-60 204.0 1.0 1.8e-60 203.7 1.0 1.1 1 0 0 1 1 1 1 PRP38 family HEAT_2 PF13646.6 EGO21665.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 HEAT repeats MAP65_ASE1 PF03999.12 EGO21665.1 - 1 8.0 10.9 1.3 7.6 10.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Fasciclin PF02469.22 EGO21667.1 - 7.8e-26 90.8 0.0 3.5e-14 53.1 0.0 3.7 3 1 0 3 3 3 2 Fasciclin domain ATP-synt_ab PF00006.25 EGO21668.1 - 1.2e-109 364.9 0.0 1.7e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGO21668.1 - 6.2e-42 142.3 0.0 1.2e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGO21668.1 - 2.2e-15 56.9 3.6 6.1e-15 55.5 3.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EGO21669.1 - 3.9e-41 140.6 0.0 9.8e-41 139.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.9 EGO21669.1 - 2.4e-39 134.8 0.0 6.6e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGO21669.1 - 1.3e-08 35.3 0.0 3.7e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_lid_3 PF17862.1 EGO21669.1 - 1.6e-05 24.6 0.1 4.9e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGO21669.1 - 0.00011 22.3 0.0 0.0003 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO21669.1 - 0.00032 21.1 0.5 0.0037 17.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGO21669.1 - 0.00036 20.8 0.0 0.011 16.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EGO21669.1 - 0.0009 19.4 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGO21669.1 - 0.00098 18.3 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) HATPase_c_3 PF13589.6 EGO21669.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RuvB_N PF05496.12 EGO21669.1 - 0.0068 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGO21669.1 - 0.0079 16.4 0.0 0.067 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO21669.1 - 0.026 14.0 0.0 0.06 12.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGO21669.1 - 0.043 14.0 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4618 PF15397.6 EGO21669.1 - 0.054 12.9 1.2 0.14 11.6 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) AAA_24 PF13479.6 EGO21669.1 - 0.059 13.1 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGO21669.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGO21669.1 - 0.077 13.5 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO21669.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EGO21669.1 - 0.099 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EGO21669.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Phlebovirus_NSM PF07246.11 EGO21669.1 - 0.12 11.8 0.4 0.21 11.0 0.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sigma54_activ_2 PF14532.6 EGO21669.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGO21669.1 - 0.15 11.9 1.5 13 5.6 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EGO21669.1 - 0.17 11.5 0.0 0.49 10.1 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGO21669.1 - 5.8 7.4 5.2 19 5.7 4.0 2.0 2 0 0 2 2 2 0 AAA domain PGM_PMM_I PF02878.16 EGO21670.1 - 5.2e-33 113.7 0.1 1.4e-32 112.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGO21670.1 - 2e-19 69.8 0.0 4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGO21670.1 - 2.5e-15 57.0 0.0 5.2e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGO21670.1 - 1.4e-05 25.2 0.0 4.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MCM_bind PF09739.9 EGO21675.1 - 4.8e-82 276.3 0.0 4e-68 230.3 0.0 3.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor CDC50 PF03381.15 EGO21676.1 - 2.6e-86 289.6 0.1 3.8e-86 289.1 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RTC PF01137.21 EGO21677.1 - 1e-80 270.1 0.2 1.2e-80 269.9 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGO21677.1 - 1.1e-20 74.1 0.4 2.3e-20 73.0 0.4 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TPR_MLP1_2 PF07926.12 EGO21678.1 - 0.0017 18.4 34.4 0.25 11.4 11.3 5.3 4 2 0 4 4 4 3 TPR/MLP1/MLP2-like protein DUF2321 PF10083.9 EGO21678.1 - 0.12 12.0 0.5 3 7.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Nup54_57_C PF18570.1 EGO21678.1 - 0.21 11.2 3.7 0.67 9.6 0.5 2.9 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain FUSC PF04632.12 EGO21678.1 - 2.4 6.6 9.3 0.082 11.4 2.3 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF16 PF01519.16 EGO21678.1 - 7.9 7.0 25.3 5 7.7 0.8 4.4 2 2 2 4 4 4 0 Protein of unknown function DUF16 HOOK PF05622.12 EGO21679.1 - 7.3e-26 90.6 18.6 7.9e-26 90.4 18.6 1.0 1 0 0 1 1 1 1 HOOK protein bZIP_1 PF00170.21 EGO21679.1 - 3.6e-05 23.8 12.4 0.0019 18.3 2.7 4.0 3 1 1 4 4 4 1 bZIP transcription factor TMF_DNA_bd PF12329.8 EGO21679.1 - 0.00034 20.5 22.5 0.16 11.9 0.6 4.0 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 EGO21679.1 - 0.00035 20.6 17.4 0.0048 17.0 13.3 2.2 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EGO21679.1 - 0.00036 20.7 14.7 0.012 15.8 6.7 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding NYD-SP28_assoc PF14775.6 EGO21679.1 - 0.00066 19.7 1.5 0.00066 19.7 1.5 2.2 2 1 0 2 2 1 1 Sperm tail C-terminal domain BLOC1_2 PF10046.9 EGO21679.1 - 0.00076 19.7 12.9 0.022 15.1 5.0 2.5 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 CEP63 PF17045.5 EGO21679.1 - 0.00081 19.4 15.1 0.0095 15.9 6.5 2.5 1 1 1 2 2 2 1 Centrosomal protein of 63 kDa DHR10 PF18595.1 EGO21679.1 - 0.0029 17.7 18.5 0.0076 16.3 8.9 2.3 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain Retrotran_gag_2 PF14223.6 EGO21679.1 - 0.0036 17.0 3.5 0.0056 16.3 1.1 2.0 1 1 0 2 2 2 1 gag-polypeptide of LTR copia-type IMD PF08397.11 EGO21679.1 - 0.0049 16.3 10.1 0.0069 15.8 9.6 1.4 1 1 0 1 1 1 1 IRSp53/MIM homology domain Fib_alpha PF08702.10 EGO21679.1 - 0.0069 16.6 7.5 0.07 13.3 5.9 2.4 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 EGO21679.1 - 0.0078 16.0 1.4 1.2 9.1 0.0 3.7 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat DUF1192 PF06698.11 EGO21679.1 - 0.0087 16.1 1.4 0.12 12.5 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Mod_r PF07200.13 EGO21679.1 - 0.0095 16.1 13.3 0.36 10.9 6.9 2.2 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 EGO21679.1 - 0.0099 15.2 17.2 0.11 11.8 17.2 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGO21679.1 - 0.014 14.3 17.4 0.068 12.0 9.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 EGO21679.1 - 0.016 15.2 11.3 0.09 12.8 5.2 2.5 1 1 2 3 3 3 0 Laminin Domain II MAD PF05557.13 EGO21679.1 - 0.017 13.6 13.2 0.041 12.2 8.4 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein bZIP_2 PF07716.15 EGO21679.1 - 0.019 15.1 2.6 0.019 15.1 2.6 3.9 3 1 1 4 4 4 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 EGO21679.1 - 0.028 14.5 16.7 0.11 12.5 7.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 EGO21679.1 - 0.032 15.1 15.4 1.5 9.7 3.8 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 EGO21679.1 - 0.034 13.6 16.6 0.22 11.0 16.6 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 EGO21679.1 - 0.034 14.2 10.4 0.052 13.6 0.4 3.7 1 1 3 4 4 4 0 TolA binding protein trimerisation DUF16 PF01519.16 EGO21679.1 - 0.035 14.6 12.7 0.17 12.4 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 EGO21679.1 - 0.035 14.2 15.6 0.087 12.9 15.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 EGO21679.1 - 0.04 12.8 15.6 0.072 12.0 9.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) KASH_CCD PF14662.6 EGO21679.1 - 0.042 13.7 16.0 0.15 11.8 9.2 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF745 PF05335.13 EGO21679.1 - 0.052 13.3 11.1 0.14 11.9 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Sec20 PF03908.13 EGO21679.1 - 0.063 13.2 5.0 0.44 10.5 0.4 2.9 1 1 2 3 3 3 0 Sec20 DUF3618 PF12277.8 EGO21679.1 - 0.066 13.5 7.9 0.2 11.9 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF4407 PF14362.6 EGO21679.1 - 0.067 12.5 11.5 0.048 13.0 9.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 EGO21679.1 - 0.07 13.4 14.4 2.5 8.5 0.2 3.5 1 1 2 3 3 3 0 Tup N-terminal HIP1_clath_bdg PF16515.5 EGO21679.1 - 0.084 13.5 1.1 0.084 13.5 1.1 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 EGO21679.1 - 0.1 12.8 20.8 0.4 10.8 10.1 2.8 1 1 2 3 3 3 0 Tropomyosin like NPV_P10 PF05531.12 EGO21679.1 - 0.13 12.8 6.8 3.7 8.1 0.1 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.8 EGO21679.1 - 0.14 11.5 18.6 3.9 6.8 8.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) KLRAQ PF10205.9 EGO21679.1 - 0.14 12.4 15.1 0.074 13.3 1.2 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein CALCOCO1 PF07888.11 EGO21679.1 - 0.14 11.0 17.2 0.56 9.0 17.2 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ZapB PF06005.12 EGO21679.1 - 0.17 12.3 17.6 7.8 7.0 9.5 3.6 1 1 2 3 3 3 0 Cell division protein ZapB SOGA PF11365.8 EGO21679.1 - 0.18 13.0 12.3 23 6.2 7.6 3.4 1 1 2 3 3 3 0 Protein SOGA DUF1664 PF07889.12 EGO21679.1 - 0.19 11.8 7.8 0.83 9.7 2.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 EGO21679.1 - 0.19 11.8 17.8 0.32 11.1 7.7 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Dynactin_p62 PF05502.13 EGO21679.1 - 0.19 10.4 4.5 0.19 10.4 4.5 1.1 1 0 0 1 1 1 0 Dynactin p62 family BORCS7 PF16088.5 EGO21679.1 - 0.24 11.7 4.0 0.45 10.8 0.1 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 Exonuc_VII_L PF02601.15 EGO21679.1 - 0.25 10.9 8.6 0.32 10.5 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 EGO21679.1 - 0.26 11.7 15.4 0.57 10.6 7.2 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.11 EGO21679.1 - 0.27 11.5 19.7 1.3 9.3 1.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 EGO21679.1 - 0.28 10.5 13.9 1.7 7.8 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 EGO21679.1 - 0.29 11.6 16.6 1.1 9.7 12.8 2.2 1 1 1 2 2 2 0 Fez1 HrpB7 PF09486.10 EGO21679.1 - 0.3 11.4 11.2 3 8.2 11.2 2.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Csm1_N PF18504.1 EGO21679.1 - 0.32 11.3 17.9 2.2 8.7 3.9 4.1 2 1 2 4 4 4 0 Csm1 N-terminal domain Surfac_D-trimer PF09006.11 EGO21679.1 - 0.34 10.8 4.0 17 5.4 0.2 3.8 3 2 1 4 4 3 0 Lung surfactant protein D coiled-coil trimerisation FlaC_arch PF05377.11 EGO21679.1 - 0.35 11.3 11.2 2.3 8.7 0.3 3.9 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 EGO21679.1 - 0.37 11.2 18.0 1.3 9.4 8.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) T3SSipB PF16535.5 EGO21679.1 - 0.51 10.8 11.5 5 7.6 8.8 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB Sec34 PF04136.15 EGO21679.1 - 0.52 10.2 8.2 1.5 8.7 4.1 2.2 1 1 1 2 2 2 0 Sec34-like family Rootletin PF15035.6 EGO21679.1 - 0.59 10.1 16.6 11 6.0 8.6 3.0 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion HemX PF04375.14 EGO21679.1 - 0.63 9.3 11.9 5.2 6.3 6.0 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cep57_CLD_2 PF14197.6 EGO21679.1 - 0.64 10.1 18.0 2.4 8.3 7.5 3.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Occludin_ELL PF07303.13 EGO21679.1 - 0.71 10.6 10.1 6 7.7 3.7 2.5 1 1 1 2 2 2 0 Occludin homology domain TSC22 PF01166.18 EGO21679.1 - 0.71 10.2 10.3 5.7 7.3 0.5 4.2 1 1 4 5 5 5 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 EGO21679.1 - 0.95 7.3 8.1 1.2 7.0 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 EGO21679.1 - 1.1 9.6 18.4 0.83 9.9 8.9 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 EGO21679.1 - 1.1 9.5 13.3 0.52 10.6 0.6 3.1 2 1 0 3 3 3 0 ABC transporter C-terminal domain BST2 PF16716.5 EGO21679.1 - 1.3 9.7 15.1 3.1 8.5 3.7 2.8 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 EGO21679.1 - 1.3 8.8 13.7 37 4.1 13.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FUSC PF04632.12 EGO21679.1 - 1.4 7.4 2.6 1.5 7.3 2.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.18 EGO21679.1 - 1.4 8.1 6.6 1.6 8.0 6.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TSNAXIP1_N PF15739.5 EGO21679.1 - 1.4 9.3 11.8 1.2 9.5 1.6 2.5 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus FapA PF03961.13 EGO21679.1 - 1.7 7.2 9.7 3.3 6.2 9.7 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A COG2 PF06148.11 EGO21679.1 - 2 8.5 10.7 18 5.4 1.8 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EGO21679.1 - 2.2 7.4 10.6 1.4 8.1 7.1 1.8 1 1 1 2 2 2 0 TMPIT-like protein YabA PF06156.13 EGO21679.1 - 2.2 8.9 11.2 76 4.0 11.2 2.8 1 1 0 1 1 1 0 Initiation control protein YabA Ntox1 PF15500.6 EGO21679.1 - 2.6 8.5 7.3 11 6.4 0.6 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 Rho_Binding PF08912.11 EGO21679.1 - 2.8 8.8 19.4 2 9.3 3.2 3.6 2 2 2 4 4 4 0 Rho Binding DUF4535 PF15054.6 EGO21679.1 - 3.3 7.5 6.0 6.4 6.6 1.0 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF4535) LMBR1 PF04791.16 EGO21679.1 - 4.4 6.1 6.9 5.2 5.9 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 EGO21679.1 - 5.5 6.8 19.4 0.16 11.8 3.4 3.8 2 1 2 4 4 4 0 Septum formation initiator DUF1515 PF07439.11 EGO21679.1 - 5.5 7.1 6.6 4.7 7.3 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF4140 PF13600.6 EGO21679.1 - 6.2 7.3 15.7 21 5.6 0.8 3.5 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 EGO21679.1 - 6.8 7.2 20.7 5.4 7.5 13.6 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Swi5 PF07061.11 EGO21679.1 - 7.2 6.8 15.9 5.4 7.2 0.3 3.7 1 1 2 3 3 3 0 Swi5 Atg14 PF10186.9 EGO21679.1 - 8.9 5.3 11.1 31 3.5 11.1 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 EGO21680.1 - 9.2e-06 24.1 0.2 9.6e-06 24.0 0.2 1.0 1 0 0 1 1 1 1 HOOK protein Sugar_tr PF00083.24 EGO21681.1 - 2.4e-79 267.3 8.0 3e-79 267.0 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO21681.1 - 2.2e-22 79.5 17.0 2.2e-22 79.5 17.0 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Not1 PF04054.15 EGO21682.1 - 2e-130 435.0 0.1 5.1e-130 433.7 0.1 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGO21682.1 - 2.6e-95 318.1 0.4 7.8e-95 316.5 0.1 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EGO21682.1 - 3.7e-54 182.6 0.9 7.9e-54 181.6 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EGO21682.1 - 9.4e-53 178.2 0.0 2.4e-52 176.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EGO21682.1 - 3.9e-44 150.3 0.9 1.4e-43 148.6 0.9 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Peptidase_S9 PF00326.21 EGO21683.1 - 5.8e-07 29.2 0.0 2.1e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGO21683.1 - 0.00041 20.1 0.0 0.00089 19.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO21683.1 - 0.0016 17.8 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 EGO21683.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EGO21683.1 - 0.0099 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 EGO21683.1 - 0.019 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DNA_pol_E_B PF04042.16 EGO21683.1 - 0.023 14.1 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Abhydrolase_2 PF02230.16 EGO21683.1 - 0.058 13.2 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TMA7 PF09072.10 EGO21684.1 - 4.2e-22 78.8 23.9 4.6e-22 78.6 23.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 WD40 PF00400.32 EGO21685.1 - 3.1e-38 129.1 4.9 8.1e-07 29.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21685.1 - 1.3e-11 44.6 0.0 0.18 12.2 0.0 5.9 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGO21685.1 - 0.00023 20.1 0.2 0.0074 15.1 0.1 2.9 2 2 1 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.6 EGO21685.1 - 0.0018 17.9 0.0 0.0048 16.5 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain TFIIA PF03153.13 EGO21685.1 - 0.023 14.7 20.5 0.036 14.1 20.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 EGO21685.1 - 0.37 9.6 12.9 0.52 9.1 12.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spt20 PF12090.8 EGO21685.1 - 1.4 8.4 24.6 2.4 7.7 24.6 1.2 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EGO21685.1 - 1.8 7.1 6.5 2.3 6.8 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.6 EGO21685.1 - 3 7.9 16.6 4.6 7.3 16.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Hid1 PF12722.7 EGO21685.1 - 4 5.4 10.2 4.8 5.2 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gastrin PF00918.17 EGO21685.1 - 6.6 7.7 9.5 13 6.8 9.5 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PDEase_II PF02112.15 EGO21686.1 - 1.1e-41 143.1 0.0 2.8e-41 141.7 0.0 1.6 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EGO21686.1 - 3.1e-06 26.9 0.0 6.8e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_4 PF12763.7 EGO21688.1 - 5.9e-36 122.6 0.0 1.5e-15 57.0 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EGO21688.1 - 1.8e-07 31.5 0.0 0.00036 20.9 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 EGO21688.1 - 1.5e-06 28.0 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CENP-F_leu_zip PF10473.9 EGO21688.1 - 0.0073 16.3 9.0 0.0073 16.3 9.0 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_1 PF00036.32 EGO21688.1 - 0.018 14.6 6.0 1.1 9.0 0.0 5.0 5 0 0 5 5 5 0 EF hand EF-hand_6 PF13405.6 EGO21688.1 - 0.083 12.9 10.1 17 5.6 0.0 5.7 6 0 0 6 6 6 0 EF-hand domain WEMBL PF05701.11 EGO21688.1 - 0.22 10.2 24.5 0.33 9.6 24.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Flagellin_C PF00700.21 EGO21688.1 - 0.22 11.9 6.6 1.5 9.2 2.6 2.9 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Fez1 PF06818.15 EGO21688.1 - 0.27 11.7 24.0 0.14 12.6 14.4 2.3 1 1 1 2 2 2 0 Fez1 CALCOCO1 PF07888.11 EGO21688.1 - 0.29 10.0 26.1 0.5 9.2 26.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 EGO21688.1 - 0.57 9.6 24.8 0.4 10.1 9.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Bcr-Abl_Oligo PF09036.10 EGO21688.1 - 1.2 9.2 4.1 1.1 9.3 0.1 2.9 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain SlyX PF04102.12 EGO21688.1 - 1.7 9.3 10.5 9.8 6.9 3.6 3.2 2 1 0 2 2 2 0 SlyX Spc7 PF08317.11 EGO21688.1 - 2.2 7.1 28.5 1.7 7.4 18.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Macoilin PF09726.9 EGO21688.1 - 2.8 6.4 15.4 5.8 5.4 15.4 1.4 1 0 0 1 1 1 0 Macoilin family DUF4477 PF14780.6 EGO21688.1 - 5.7 6.5 6.0 3.7 7.1 1.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4477) DUF1664 PF07889.12 EGO21688.1 - 5.9 7.0 13.2 0.62 10.1 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UQ_con PF00179.26 EGO21689.1 - 7.7e-45 152.0 0.0 9.3e-45 151.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGO21689.1 - 0.00014 22.1 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGO21689.1 - 0.0028 17.4 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B R3H PF01424.22 EGO21691.1 - 2.5e-10 40.2 0.1 6.3e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EGO21691.1 - 8.4e-08 31.9 0.0 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 EGO21691.1 - 0.016 15.2 0.5 0.063 13.3 0.5 2.1 1 0 0 1 1 1 0 SUZ-C motif Endonuclease_NS PF01223.23 EGO21695.1 - 2.8e-59 200.7 0.0 3.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease V-ATPase_H_N PF03224.14 EGO21696.1 - 2.4e-88 296.5 0.3 3.4e-88 296.0 0.3 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGO21696.1 - 2.3e-44 150.2 0.4 2.9e-43 146.7 0.1 2.5 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.22 EGO21696.1 - 0.0012 18.9 1.8 0.5 10.8 0.1 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EGO21696.1 - 0.049 14.0 0.1 0.99 9.8 0.0 2.9 2 1 0 2 2 2 0 HEAT repeats DUF3949 PF13133.6 EGO21696.1 - 0.44 11.0 2.3 0.63 10.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) RNA12 PF10443.9 EGO21697.1 - 6.1e-115 384.5 0.0 2.1e-63 214.6 0.0 2.4 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 EGO21697.1 - 6e-05 23.5 0.5 0.00021 21.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EGO21697.1 - 0.0011 18.9 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGO21697.1 - 0.0026 18.0 0.0 0.0088 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain RRM_1 PF00076.22 EGO21697.1 - 0.0026 17.5 0.0 0.008 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_6 PF12774.7 EGO21697.1 - 0.0048 15.9 0.0 0.0083 15.1 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 EGO21697.1 - 0.05 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO21697.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGO21697.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Cep57_CLD PF14073.6 EGO21697.1 - 3.7 7.5 7.8 0.12 12.4 1.2 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 TMA7 PF09072.10 EGO21698.1 - 0.27 12.1 1.1 0.55 11.1 1.1 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 Nucleoporin_FG PF13634.6 EGO21701.1 - 0.00033 21.5 38.2 0.00068 20.4 27.1 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region Tubulin PF00091.25 EGO21703.1 - 7.6e-70 235.1 0.0 2.5e-69 233.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO21703.1 - 3e-46 156.7 0.4 5.7e-46 155.8 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGO21703.1 - 0.00025 20.8 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGO21703.1 - 0.00066 20.0 0.0 0.0031 17.8 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Hrs_helical PF12210.8 EGO21703.1 - 0.11 13.1 0.4 0.24 12.0 0.4 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MBF1 PF08523.10 EGO21704.1 - 2e-25 89.0 2.5 4.2e-25 88.0 2.5 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGO21704.1 - 5.9e-13 48.7 0.1 8.8e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EGO21704.1 - 7.8e-05 22.6 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EGO21704.1 - 9.3e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EGO21704.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain FAD-oxidase_C PF02913.19 EGO21705.1 - 2.8e-54 184.4 0.0 4.1e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO21705.1 - 8.1e-24 83.9 0.2 2.8e-23 82.2 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain PAD PF03068.15 EGO21705.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Bmt2 PF11968.8 EGO21706.1 - 6e-58 196.3 0.0 6.7e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EGO21706.1 - 5.5e-05 23.1 0.0 7.7e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain TrbC PF04956.13 EGO21707.1 - 0.031 14.5 0.5 0.031 14.5 0.5 2.8 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF1616 PF07760.11 EGO21707.1 - 0.41 10.0 5.7 0.2 11.0 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Tetraspanin PF00335.20 EGO21707.1 - 0.43 10.3 21.1 2 8.1 21.1 2.5 1 1 0 1 1 1 0 Tetraspanin family DUF4191 PF13829.6 EGO21707.1 - 0.52 9.6 10.3 1.7 7.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) Gram_pos_anchor PF00746.21 EGO21707.1 - 1.3 9.0 3.0 7 6.7 0.1 3.2 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF4199 PF13858.6 EGO21707.1 - 1.6 9.1 15.0 0.66 10.4 3.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Baculo_11_kDa PF06143.11 EGO21707.1 - 4.5 6.9 8.1 1.9 8.1 0.2 2.7 2 1 0 2 2 2 0 Baculovirus 11 kDa family NAD_binding_7 PF13241.6 EGO21708.1 - 2.1e-28 98.8 0.0 5e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EGO21708.1 - 2.7e-23 81.4 0.3 4.4e-23 80.7 0.3 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EGO21708.1 - 1.1e-15 56.7 0.3 2.3e-15 55.7 0.3 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 EGO21708.1 - 0.27 10.6 0.8 2.7 7.3 0.1 2.3 2 1 1 3 3 3 0 ThiF family 5_nucleotid_C PF02872.18 EGO21709.1 - 6e-26 91.6 0.0 1.7e-25 90.1 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGO21709.1 - 1.2e-09 39.0 0.9 2e-09 38.3 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EGO21709.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DUF2420 PF10336.9 EGO21711.1 - 2.5e-08 33.9 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Integrase_Zn PF02022.19 EGO21711.1 - 0.054 13.5 0.4 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain RNA_pol_Rpc82 PF05645.13 EGO21712.1 - 2.6e-17 63.4 8.5 8.3e-16 58.5 1.2 3.8 5 0 0 5 5 5 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EGO21712.1 - 5.6e-16 58.4 1.3 5.7e-12 45.6 0.2 3.1 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EGO21712.1 - 1.4e-09 37.7 0.3 6.9e-07 29.1 0.0 4.1 4 1 0 4 4 4 1 TFIIE alpha subunit Metallophos PF00149.28 EGO21713.1 - 0.047 14.2 0.2 0.086 13.3 0.2 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF572 PF04502.13 EGO21714.1 - 1.9e-81 274.3 5.9 2.1e-81 274.1 5.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 EGO21714.1 - 0.059 13.3 0.3 0.094 12.6 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.14 EGO21714.1 - 0.096 12.6 0.8 3.8 7.5 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SPT16 PF08644.11 EGO21715.1 - 1.6e-58 197.1 1.3 2.3e-58 196.7 0.1 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EGO21715.1 - 8.1e-30 103.7 0.1 3.8e-28 98.3 0.1 2.8 1 1 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGO21715.1 - 9.2e-22 77.8 0.0 1.5e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGO21715.1 - 1.3e-15 57.6 0.0 3.7e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 EGO21715.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Abhydrolase_1 PF00561.20 EGO21716.1 - 1.1e-16 61.3 0.2 3.1e-15 56.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO21716.1 - 6.1e-16 58.4 0.0 9.7e-16 57.8 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO21716.1 - 3e-10 41.1 0.1 3.9e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGO21716.1 - 0.0031 17.4 0.0 0.05 13.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EGO21716.1 - 0.012 15.1 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2048 PF09752.9 EGO21716.1 - 0.023 13.8 0.1 0.057 12.5 0.1 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Thioesterase PF00975.20 EGO21716.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 EGO21716.1 - 0.073 13.0 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 EGO21716.1 - 0.15 11.9 0.0 2.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGO21716.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein GST_N_3 PF13417.6 EGO21717.1 - 1.1e-08 35.4 0.0 4.1e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO21717.1 - 2.5e-07 30.9 0.0 4.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO21717.1 - 0.00032 20.8 0.0 0.0007 19.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO21717.1 - 0.0006 19.8 0.5 0.0027 17.7 0.3 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO21717.1 - 0.0038 17.4 0.1 0.0093 16.1 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PEGSRP PF07623.11 EGO21717.1 - 0.031 14.0 0.2 0.075 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) FMN_dh PF01070.18 EGO21718.1 - 2.2e-107 359.1 0.0 2.8e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGO21718.1 - 1.5e-17 63.5 0.0 2.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EGO21718.1 - 0.00018 20.6 0.4 0.0013 17.9 0.4 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGO21718.1 - 0.00021 20.6 0.2 0.00039 19.7 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 EGO21718.1 - 0.00047 19.6 0.1 0.00087 18.8 0.0 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase P66_CC PF16563.5 EGO21718.1 - 1.9 8.1 4.4 4.1 7.1 4.4 1.5 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Quaking_NLS PF16551.5 EGO21720.1 - 0.043 13.5 0.8 0.074 12.7 0.8 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking zf-C2HC PF01530.18 EGO21722.1 - 1.5 9.1 3.4 0.58 10.4 0.5 1.8 2 0 0 2 2 2 0 Zinc finger, C2HC type zinc_ribbon_10 PF10058.9 EGO21727.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Mis12 PF05859.12 EGO21730.1 - 1.2e-38 132.2 0.2 1.8e-38 131.7 0.2 1.3 1 0 0 1 1 1 1 Mis12 protein MetOD2 PF18548.1 EGO21730.1 - 0.074 13.2 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Metanogen output domain 2 DEAD PF00270.29 EGO21732.1 - 1.5e-44 151.8 0.6 3.1e-44 150.9 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21732.1 - 3.5e-22 78.8 0.4 7.1e-21 74.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO21732.1 - 1.6e-08 34.8 0.0 3.8e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO21732.1 - 0.0047 16.2 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 EGO21732.1 - 0.015 15.2 0.1 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 Helicase Blt1 PF12754.7 EGO21732.1 - 0.019 15.3 1.9 0.81 10.0 0.1 2.6 2 0 0 2 2 2 0 Blt1 N-terminal domain DUF2075 PF09848.9 EGO21732.1 - 0.033 13.4 0.0 0.096 11.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGO21732.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain dsDNA_bind PF01984.20 EGO21733.1 - 9.4e-20 70.9 2.8 9.7e-20 70.9 2.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain MUG113 PF13455.6 EGO21734.1 - 1.8e-13 50.9 0.0 9.5e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EGO21734.1 - 1.2e-10 41.8 0.0 1.3e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 T5orf172 domain AAA_32 PF13654.6 EGO21734.1 - 0.19 10.5 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3535 PF12054.8 EGO21736.1 - 5.6e-88 296.1 1.6 3.6e-87 293.4 0.1 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) UCH_1 PF13423.6 EGO21736.1 - 4e-85 286.2 0.0 6.2e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SNF2_N PF00176.23 EGO21736.1 - 9.7e-66 221.9 0.0 1.6e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain RNase_T PF00929.24 EGO21736.1 - 1.5e-20 74.4 0.1 5.6e-20 72.5 0.0 2.1 3 0 0 3 3 3 1 Exonuclease Helicase_C PF00271.31 EGO21736.1 - 8.9e-16 58.2 0.0 2.9e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGO21736.1 - 5.5e-13 48.0 10.2 1.2 9.5 0.4 9.2 9 0 0 9 9 8 5 HEAT repeat UCH PF00443.29 EGO21736.1 - 0.00031 20.3 0.0 0.00086 18.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HEAT_EZ PF13513.6 EGO21736.1 - 0.00032 21.1 8.0 39 4.9 0.0 7.4 6 2 1 7 7 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGO21736.1 - 0.0015 19.1 0.1 4.4 8.0 0.0 2.9 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region ResIII PF04851.15 EGO21736.1 - 0.0019 18.2 0.0 0.006 16.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3385 PF11865.8 EGO21736.1 - 0.0024 17.8 0.1 0.0064 16.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EGO21736.1 - 0.061 12.9 0.0 0.68 9.5 0.0 2.7 1 1 0 1 1 1 0 CLASP N terminal Cupin_8 PF13621.6 EGO21737.1 - 2.3e-33 116.0 0.0 3.7e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGO21737.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGO21737.1 - 0.0011 19.3 0.0 0.022 15.2 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGO21737.1 - 0.0071 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain SOG2 PF10428.9 EGO21738.1 - 1.3e-79 268.8 1.3 1.3e-79 268.8 1.3 3.2 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 EGO21738.1 - 2.4e-13 49.6 6.2 8.7e-07 28.6 0.1 2.8 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGO21738.1 - 3.1e-13 49.7 11.9 3.2e-06 27.4 0.0 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO21738.1 - 0.00033 20.8 3.0 16 6.5 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 EGO21738.1 - 0.0042 16.6 1.0 0.0087 15.6 1.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 EGO21738.1 - 0.019 15.0 1.0 17 5.8 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat FYVE PF01363.21 EGO21739.1 - 1.2e-17 63.7 3.2 2.1e-17 63.0 3.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 EGO21739.1 - 1.6e-15 56.5 1.1 4.4e-15 55.1 1.1 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 EGO21739.1 - 0.0026 17.7 8.0 0.0036 17.2 6.2 2.0 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.16 EGO21739.1 - 0.013 15.7 2.7 0.041 14.1 0.6 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Occludin_ELL PF07303.13 EGO21739.1 - 0.026 15.2 1.1 0.095 13.4 0.1 2.2 2 0 0 2 2 2 0 Occludin homology domain Lin-8 PF03353.15 EGO21740.1 - 0.21 11.1 0.2 0.21 11.1 0.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cofilin_ADF PF00241.20 EGO21741.1 - 3e-31 107.7 0.0 1.8e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CoA_trans PF01144.23 EGO21742.1 - 2.6e-98 327.8 2.5 9.2e-59 198.5 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EGO21742.1 - 9.9e-05 22.3 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain EIIBC-GUT_N PF03612.14 EGO21742.1 - 0.086 12.6 0.1 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Cauli_VI PF01693.16 EGO21743.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Alpha_kinase PF02816.18 EGO21745.1 - 8e-18 65.2 0.0 9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family CoA_trans PF01144.23 EGO21746.1 - 1.3e-103 345.1 4.5 3.2e-62 209.8 0.5 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EGO21746.1 - 0.00031 20.7 0.1 0.0006 19.8 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EGO21746.1 - 0.15 12.0 0.1 2.6 8.0 0.0 2.7 4 0 0 4 4 4 0 Acetyl-CoA hydrolase/transferase N-terminal domain SMI1_KNR4 PF09346.10 EGO21747.1 - 2e-23 83.3 0.0 3.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Aldedh PF00171.22 EGO21748.1 - 8.5e-121 403.7 0.0 1e-120 403.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.18 EGO21752.1 - 1.1e-09 38.1 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pectate_lyase_3 PF12708.7 EGO21753.1 - 1.5e-72 243.9 28.0 8.8e-57 192.4 5.2 4.0 4 0 0 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO21753.1 - 3.7e-08 32.9 1.6 8.6e-05 22.1 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Pkinase PF00069.25 EGO21757.1 - 8.2e-64 215.5 0.0 9.6e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21757.1 - 2.5e-24 86.0 0.0 3.2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO21757.1 - 0.00013 21.4 0.0 0.00033 20.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGO21757.1 - 0.0014 18.6 0.1 0.049 13.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO21757.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EGO21757.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGO21757.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 EGO21758.1 - 4.9e-47 156.9 23.7 5e-07 30.3 0.1 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat F-box-like PF12937.7 EGO21758.1 - 5.8e-11 42.1 0.4 1.2e-10 41.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO21758.1 - 3.4e-10 39.5 0.3 9.9e-10 38.1 0.3 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EGO21758.1 - 4e-08 32.4 6.3 1 7.9 0.0 6.0 3 1 1 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGO21758.1 - 2.5e-06 27.7 0.2 7.3 7.0 0.1 5.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGO21758.1 - 0.00011 22.2 0.0 12 6.0 0.0 5.0 5 1 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 EGO21758.1 - 0.0018 18.1 0.2 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 F-box COQ7 PF03232.13 EGO21760.1 - 3.8e-66 222.1 0.6 4.5e-66 221.8 0.6 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.12 EGO21761.1 - 0.00014 21.8 0.1 0.00016 21.6 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.23 EGO21762.1 - 1.7e-14 53.5 2.5 3.7e-14 52.3 2.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGO21762.1 - 3.8e-06 26.9 2.2 1e-05 25.5 2.2 1.8 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 EGO21762.1 - 0.0085 16.4 1.3 0.017 15.4 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RED_N PF07808.13 EGO21762.1 - 0.011 15.4 0.4 0.025 14.2 0.4 1.6 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_11 PF16622.5 EGO21762.1 - 0.045 13.5 0.4 0.085 12.6 0.4 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type RRM_1 PF00076.22 EGO21762.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 EGO21762.1 - 0.14 12.5 0.4 0.25 11.7 0.4 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Exo5 PF09810.9 EGO21766.1 - 1e-63 216.1 0.7 3.6e-55 188.0 0.2 2.6 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease Metal_resist PF13801.6 EGO21766.1 - 0.059 13.6 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Heavy-metal resistance PDDEXK_1 PF12705.7 EGO21766.1 - 0.12 12.2 0.1 3.6 7.4 0.0 2.6 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Ras PF00071.22 EGO21767.1 - 1.5e-53 180.7 0.0 1.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO21767.1 - 6e-22 78.1 0.0 8.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21767.1 - 8.2e-07 28.6 0.0 2e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGO21767.1 - 0.0013 18.6 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GnsAB_toxin PF08178.11 EGO21767.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system PduV-EutP PF10662.9 EGO21767.1 - 0.15 11.8 0.1 1.9 8.2 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EGO21767.1 - 0.16 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region rve PF00665.26 EGO21768.1 - 0.034 14.3 0.0 0.034 14.3 0.0 1.0 1 0 0 1 1 1 0 Integrase core domain NACHT PF05729.12 EGO21769.1 - 0.0095 15.9 0.0 0.025 14.5 0.0 1.7 1 1 1 2 2 2 1 NACHT domain DUF5071 PF16804.5 EGO21769.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) Bee_toxin PF17454.2 EGO21770.1 - 0.13 12.3 0.7 0.23 11.5 0.7 1.4 1 0 0 1 1 1 0 Honey bee toxin Pyr_redox_2 PF07992.14 EGO21771.1 - 8.3e-66 222.2 0.3 1.1e-65 221.8 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGO21771.1 - 2.3e-32 111.5 0.4 6.9e-32 110.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGO21771.1 - 4.1e-21 75.3 4.1 1e-18 67.6 0.2 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO21771.1 - 7.5e-16 58.2 0.7 4e-15 55.9 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO21771.1 - 1e-08 34.7 0.0 3.5e-08 33.0 0.0 1.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGO21771.1 - 1.8e-07 30.2 0.9 0.0048 15.6 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 EGO21771.1 - 1.8e-07 30.9 0.0 4.9e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO21771.1 - 0.00078 19.6 0.6 0.00078 19.6 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGO21771.1 - 0.0037 16.4 0.5 0.0037 16.4 0.5 2.9 3 1 0 4 4 4 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGO21771.1 - 0.012 14.6 0.3 2.1 7.3 0.0 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO21771.1 - 0.035 13.2 1.7 0.07 12.2 1.0 1.8 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 EGO21771.1 - 0.037 13.3 0.2 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EGO21771.1 - 0.11 12.0 5.5 0.97 8.9 0.1 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO21771.1 - 0.14 11.4 0.3 3.6 6.7 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 EGO21771.1 - 0.15 12.0 1.1 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EGO21771.1 - 0.79 9.7 0.0 0.79 9.7 0.0 2.6 4 0 0 4 4 3 0 FAD-NAD(P)-binding Asp_Glu_race PF01177.22 EGO21772.1 - 1.7e-05 24.8 0.0 3.2e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase LdpA_C PF12617.8 EGO21772.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Retrotrans_gag PF03732.17 EGO21775.1 - 4.3e-07 30.1 0.1 4.3e-07 30.1 0.1 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein DUF1191 PF06697.12 EGO21776.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Hat1_N PF10394.9 EGO21779.1 - 2.3e-56 190.4 0.1 4e-56 189.7 0.1 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EGO21779.1 - 6.5e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EGO21779.1 - 0.00071 19.3 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_3 PF13302.7 EGO21779.1 - 0.025 15.3 0.1 0.061 14.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO21779.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO21779.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sterol-sensing PF12349.8 EGO21780.1 - 2.2e-37 128.2 6.8 3.9e-36 124.2 6.1 3.0 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGO21780.1 - 1.1e-15 56.9 0.4 1.5e-15 56.4 0.4 1.1 1 0 0 1 1 1 1 Patched family Biotin_lipoyl PF00364.22 EGO21781.1 - 6.2e-19 67.6 1.1 1.2e-18 66.6 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGO21781.1 - 2.4e-06 27.8 0.0 5.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGO21781.1 - 0.087 12.7 0.0 1 9.2 0.0 2.5 3 0 0 3 3 3 0 Biotin-lipoyl like SspB PF04386.13 EGO21781.1 - 0.13 12.2 5.0 1.1 9.1 0.8 2.5 2 1 0 2 2 2 0 Stringent starvation protein B DUF1631 PF07793.11 EGO21781.1 - 0.17 10.3 1.6 0.23 9.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Rad1 PF02144.16 EGO21782.1 - 4.4e-73 245.7 0.0 5.2e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 LDcluster4 PF18306.1 EGO21784.1 - 0.0016 18.0 1.8 0.002 17.8 1.8 1.1 1 0 0 1 1 1 1 SLOG cluster4 family tRNA-synt_1b PF00579.25 EGO21785.1 - 5.6e-21 75.1 0.0 1.1e-20 74.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TBP PF00352.21 EGO21786.1 - 3.4e-66 219.2 0.2 3e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGO21786.1 - 0.00012 22.1 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EGO21786.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) TFIIA PF03153.13 EGO21786.1 - 1.3 8.9 4.8 1.7 8.5 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 EGO21786.1 - 3.6 6.1 5.2 4.4 5.9 5.2 1.1 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_88 PF07470.13 EGO21788.1 - 2.1e-13 50.1 0.5 2.4e-13 49.9 0.5 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EGO21788.1 - 0.015 14.8 0.4 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus PQQ_2 PF13360.6 EGO21788.1 - 0.031 13.9 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 EGO21788.1 - 0.044 13.7 0.4 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat Dynamin_M PF01031.20 EGO21789.1 - 9.9e-102 340.0 0.0 1.7e-101 339.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGO21789.1 - 7.9e-55 185.5 0.0 1.8e-54 184.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGO21789.1 - 6.8e-29 99.9 2.4 6.8e-29 99.9 2.4 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO21789.1 - 8.1e-05 22.7 0.1 0.0013 18.8 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EGO21789.1 - 0.07 12.8 0.4 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NTF2 PF02136.20 EGO21790.1 - 1.2e-29 103.3 0.0 1.4e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3549 PF12069.8 EGO21790.1 - 0.054 12.5 0.0 0.092 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3549) T4_baseplate PF12322.8 EGO21790.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-RING_5 PF14634.6 EGO21792.1 - 6.5e-05 22.8 13.4 0.00077 19.4 9.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGO21792.1 - 7.5e-05 22.5 10.4 0.0088 15.9 7.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO21792.1 - 0.00023 21.4 12.3 0.0022 18.3 9.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO21792.1 - 0.00024 21.1 10.6 0.0005 20.0 7.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO21792.1 - 0.0043 16.9 9.9 0.0043 16.9 9.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO21792.1 - 0.013 15.3 11.0 1.2 9.1 7.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 YacG PF03884.14 EGO21792.1 - 0.019 14.7 2.2 0.7 9.7 0.2 2.8 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG TerY_C PF15616.6 EGO21792.1 - 0.021 14.9 5.6 0.92 9.6 2.7 2.5 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C3HC4 PF00097.25 EGO21792.1 - 0.024 14.5 12.5 0.026 14.4 7.6 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO21792.1 - 0.041 14.1 11.2 0.049 13.8 7.6 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SAP PF02037.27 EGO21792.1 - 0.047 13.5 0.4 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 SAP domain zf-RING_6 PF14835.6 EGO21792.1 - 0.47 10.4 5.3 0.15 12.0 2.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein NMD3 PF04981.13 EGO21792.1 - 0.95 8.9 11.2 0.13 11.7 4.9 2.5 2 1 0 2 2 2 0 NMD3 family zf-RING_4 PF14570.6 EGO21792.1 - 2.1 8.2 10.8 2.9 7.8 4.0 2.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain HypA PF01155.19 EGO21792.1 - 4.4 7.3 8.9 54 3.8 0.0 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 EGO21792.1 - 7.2 7.0 11.5 2.1 8.7 0.1 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FeS_assembly_P PF01883.19 EGO21795.1 - 1.1e-13 51.2 0.1 2.3e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein DUF371 PF04027.13 EGO21795.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF371) BRCT_2 PF16589.5 EGO21797.1 - 7e-07 29.6 0.0 9.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SWIRM-assoc_2 PF16496.5 EGO21797.1 - 0.031 13.1 0.1 0.043 12.7 0.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MIF PF01187.18 EGO21798.1 - 1.6e-13 50.9 0.0 1.8e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.18 EGO21799.1 - 7.9e-13 48.7 0.0 9e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) CPSase_C PF18302.1 EGO21801.1 - 0.27 11.7 2.2 3.5 8.4 0.2 3.1 2 0 0 2 2 2 0 Carbamoyl phosphate synthetase C-terminal domain MIF PF01187.18 EGO21802.1 - 2.2e-12 47.3 0.0 2.5e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_3 PF07969.11 EGO21803.1 - 4.5e-15 56.1 0.1 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO21803.1 - 3.5e-11 43.0 0.0 3.5e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 EGO21803.1 - 0.0018 18.2 0.5 2.3 8.3 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Methyltransf_PK PF05891.12 EGO21804.1 - 2.5e-55 187.4 0.1 4e-53 180.2 0.1 2.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGO21804.1 - 1.1e-06 29.2 0.0 0.057 14.1 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGO21804.1 - 3.2e-06 27.7 0.3 0.0002 21.9 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO21804.1 - 0.00041 21.0 0.0 0.0016 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGO21804.1 - 0.063 12.6 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Rpp20 PF12328.8 EGO21805.1 - 2.5e-05 24.3 6.2 0.00071 19.5 0.1 3.9 2 1 2 4 4 4 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EGO21805.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Alba DUF3568 PF12092.8 EGO21805.1 - 0.21 11.6 1.0 0.45 10.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) eRF1_2 PF03464.15 EGO21806.1 - 6.9e-47 159.1 0.1 1.2e-46 158.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGO21806.1 - 1.5e-37 128.5 0.3 3e-37 127.6 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGO21806.1 - 1.9e-19 69.9 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EGO21806.1 - 5.6e-10 39.6 0.2 8.9e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EGO21806.1 - 5.9e-09 36.3 0.1 1e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 BAALC_N PF06989.12 EGO21807.1 - 0.054 13.8 0.2 0.21 11.9 0.2 2.0 1 0 0 1 1 1 0 BAALC N-terminus Phosducin PF02114.16 EGO21808.1 - 4.4e-07 29.1 0.0 8.2e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Phosducin Ribonuclease_3 PF00636.26 EGO21809.1 - 5.9e-40 136.1 0.0 5.4e-19 68.8 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGO21809.1 - 2.1e-26 92.6 1.9 4.1e-14 52.8 0.1 4.5 3 2 0 3 3 3 2 Ribonuclease-III-like ResIII PF04851.15 EGO21809.1 - 1.9e-16 60.6 0.1 3.4e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 EGO21809.1 - 2.9e-15 56.2 0.1 1.1e-14 54.4 0.1 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 EGO21809.1 - 3.4e-14 53.0 0.0 6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO21809.1 - 9.3e-14 51.7 0.0 5.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EGO21809.1 - 6.9e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Spermine_synt_N PF17284.2 EGO21809.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain Ras PF00071.22 EGO21810.1 - 4.8e-54 182.3 0.0 5.5e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO21810.1 - 3.9e-19 69.0 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21810.1 - 9.2e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO21810.1 - 0.034 13.7 0.0 0.23 11.0 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 EGO21811.1 - 5.7e-34 115.8 0.0 4.4e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO21811.1 - 0.079 13.1 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif DUF1077 PF06417.12 EGO21812.1 - 1.6e-47 160.3 0.2 2e-47 160.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF4029 PF13221.6 EGO21813.1 - 0.55 10.9 8.5 0.63 10.7 8.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) PIG-X PF08320.12 EGO21814.1 - 7.6e-36 124.0 0.1 9.5e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 ADK PF00406.22 EGO21815.1 - 4.3e-60 202.2 0.0 5.7e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGO21815.1 - 2.3e-22 79.9 0.2 5.5e-22 78.7 0.1 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EGO21815.1 - 7.1e-17 61.1 0.0 1.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGO21815.1 - 0.0012 19.4 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO21815.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EGO21815.1 - 0.092 13.0 0.1 4.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Retrotrans_gag PF03732.17 EGO21815.1 - 0.16 12.2 0.1 0.91 9.8 0.0 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein Beta-lactamase PF00144.24 EGO21816.1 - 3.6e-28 98.8 0.1 5e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DDOST_48kD PF03345.14 EGO21818.1 - 6.3e-128 427.2 0.0 7.4e-128 426.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Nsp1_C PF05064.13 EGO21819.1 - 0.17 11.7 1.1 0.32 10.8 1.1 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region APG6_N PF17675.1 EGO21819.1 - 0.27 11.8 7.4 0.5 10.9 7.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 EGO21819.1 - 0.3 11.7 4.6 0.65 10.6 4.6 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Asp PF00026.23 EGO21821.1 - 5e-28 98.4 0.1 5.4e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGO21821.1 - 2.9e-06 27.1 0.0 3.7e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal V_ATPase_I PF01496.19 EGO21822.1 - 0 1046.1 0.0 0 1045.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ABC_tran PF00005.27 EGO21823.1 - 1.5e-42 145.4 0.0 2.6e-20 73.3 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO21823.1 - 2.4e-16 60.4 3.8 1e-06 28.8 0.9 4.8 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO21823.1 - 2e-12 47.0 1.0 0.0052 16.3 0.1 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO21823.1 - 9.1e-08 31.7 0.2 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EGO21823.1 - 1.2e-05 25.5 0.0 0.0047 17.1 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 EGO21823.1 - 1.9e-05 25.2 0.1 0.067 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO21823.1 - 2.5e-05 24.7 0.4 0.029 14.8 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 EGO21823.1 - 3.4e-05 24.1 0.0 0.26 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EGO21823.1 - 4.2e-05 23.6 0.4 0.22 11.6 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO21823.1 - 4.3e-05 23.5 0.1 0.12 12.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EGO21823.1 - 7.2e-05 23.2 0.0 2.6 8.5 0.0 4.1 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Chromo PF00385.24 EGO21823.1 - 9.1e-05 22.3 0.2 0.00021 21.2 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNA_helicase PF00910.22 EGO21823.1 - 0.0001 22.6 0.1 0.46 10.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.6 EGO21823.1 - 0.00011 22.5 0.0 0.58 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EGO21823.1 - 0.0002 21.2 0.3 0.4 10.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGO21823.1 - 0.00025 21.0 0.1 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 EGO21823.1 - 0.00034 19.7 0.4 0.29 10.1 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EGO21823.1 - 0.0004 21.0 11.3 0.01 16.3 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EGO21823.1 - 0.00064 19.9 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EGO21823.1 - 0.00066 19.7 0.4 3.8 7.4 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGO21823.1 - 0.0024 17.4 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 EGO21823.1 - 0.0044 17.2 0.1 1.2 9.4 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EGO21823.1 - 0.0047 16.7 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EGO21823.1 - 0.0048 16.6 0.0 4 7.0 0.0 3.9 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 EGO21823.1 - 0.0079 15.4 0.2 2.8 7.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 EGO21823.1 - 0.01 15.6 0.2 4.9 6.8 0.2 2.9 3 0 0 3 3 2 0 AAA domain HEAT PF02985.22 EGO21823.1 - 0.013 15.7 4.3 12 6.5 0.0 5.0 5 0 0 5 5 3 0 HEAT repeat AAA_13 PF13166.6 EGO21823.1 - 0.022 13.5 0.0 2.1 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGO21823.1 - 0.023 14.7 0.6 7.5 6.6 0.1 2.7 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4HB PF17947.1 EGO21823.1 - 0.024 14.7 0.0 0.079 13.0 0.0 1.9 1 0 0 1 1 1 0 Four helical bundle domain HEAT_2 PF13646.6 EGO21823.1 - 0.029 14.8 8.5 0.082 13.3 0.1 3.4 3 1 0 3 3 2 0 HEAT repeats Roc PF08477.13 EGO21823.1 - 0.029 14.6 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EGO21823.1 - 0.036 13.3 0.0 5.3 6.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 EGO21823.1 - 0.044 13.6 0.1 12 5.7 0.0 2.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Dynamin_N PF00350.23 EGO21823.1 - 0.072 13.1 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 EGO21823.1 - 0.1 12.5 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 NTPase FERM_N PF09379.10 EGO21823.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain AAA_27 PF13514.6 EGO21823.1 - 0.11 12.0 0.8 11 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EGO21823.1 - 0.15 11.3 0.1 3.1 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family U3snoRNP10 PF12397.8 EGO21823.1 - 0.23 11.8 1.6 1 9.7 1.6 2.2 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 AAA_5 PF07728.14 EGO21823.1 - 0.29 11.1 4.9 18 5.3 0.1 4.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EGO21823.1 - 0.43 10.1 3.1 15 5.2 0.1 3.6 4 1 1 5 5 3 0 CobW/HypB/UreG, nucleotide-binding domain HEAT_EZ PF13513.6 EGO21823.1 - 1 9.9 8.4 11 6.7 0.1 5.5 5 2 2 7 7 6 0 HEAT-like repeat Peptidase_M50B PF13398.6 EGO21824.1 - 1.5e-56 191.3 20.4 2.1e-56 190.7 20.4 1.2 1 0 0 1 1 1 1 Peptidase M50B-like ECSCR PF15820.5 EGO21824.1 - 0.29 11.0 1.8 12 5.8 0.1 2.6 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator VCBS PF13517.6 EGO21825.1 - 1.1e-27 96.4 15.7 1.2e-09 38.6 0.2 5.4 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGO21825.1 - 3.3e-07 30.3 25.3 0.29 11.3 0.0 7.0 7 0 0 7 7 7 4 FG-GAP repeat Dockerin_1 PF00404.18 EGO21825.1 - 3.4 7.9 7.3 8.4 6.7 0.0 4.6 7 0 0 7 7 7 0 Dockerin type I domain rhaM PF05336.13 EGO21826.1 - 1.3e-32 112.1 0.3 1.5e-32 111.9 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Ras PF00071.22 EGO21827.1 - 2e-61 206.3 0.2 2.5e-61 206.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO21827.1 - 9.6e-35 119.4 0.1 1.3e-34 119.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO21827.1 - 6.9e-13 48.4 0.0 9e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO21827.1 - 7.9e-08 32.4 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO21827.1 - 0.0001 21.9 0.2 0.00047 19.8 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO21827.1 - 0.00018 21.4 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGO21827.1 - 0.0034 17.7 0.0 0.051 13.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain FeoB_N PF02421.18 EGO21827.1 - 0.0039 16.7 0.1 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EGO21827.1 - 0.0052 16.2 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO21827.1 - 0.012 15.1 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGO21827.1 - 0.015 15.7 0.1 0.032 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF3533 PF12051.8 EGO21827.1 - 0.033 13.1 0.3 0.038 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_24 PF13479.6 EGO21827.1 - 0.037 13.7 0.0 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGO21827.1 - 0.04 13.7 0.0 0.088 12.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGO21827.1 - 0.043 14.3 0.1 0.069 13.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 EGO21827.1 - 0.054 12.7 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 EGO21827.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGO21827.1 - 0.077 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 EGO21827.1 - 0.085 11.9 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 EGO21827.1 - 0.088 12.6 0.1 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system VirE PF05272.11 EGO21827.1 - 0.091 12.5 0.1 4.5 7.0 0.0 2.3 2 1 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 EGO21827.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 EGO21830.1 - 2.7e-42 142.0 17.0 1.4e-07 32.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21830.1 - 2.5e-21 75.8 0.1 4.2e-07 30.2 0.1 6.1 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO21830.1 - 7.8e-09 34.9 0.6 0.042 12.8 0.0 4.4 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO21830.1 - 4.7e-08 33.1 0.4 1.1e-05 25.4 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EGO21830.1 - 0.00087 18.4 0.0 0.0016 17.6 0.0 1.4 1 1 0 1 1 1 1 Coatomer WD associated region Nucleoporin_N PF08801.11 EGO21830.1 - 0.0013 17.5 0.0 1.9 7.2 0.0 3.3 1 1 2 3 3 3 2 Nup133 N terminal like IKI3 PF04762.12 EGO21830.1 - 0.011 13.8 0.1 0.03 12.3 0.0 1.6 2 0 0 2 2 2 0 IKI3 family Nbas_N PF15492.6 EGO21830.1 - 0.055 12.8 0.2 6.9 5.9 0.0 3.6 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Det1 PF09737.9 EGO21830.1 - 0.31 10.1 0.0 0.45 9.5 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Histone PF00125.24 EGO21831.1 - 1.9e-43 148.0 4.8 2.4e-43 147.6 4.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGO21831.1 - 8.4e-06 25.9 0.2 1.5e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGO21831.1 - 7.8e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO21831.1 - 0.0017 18.6 0.2 0.0031 17.7 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGO21831.1 - 0.15 12.1 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated PP2C PF00481.21 EGO21832.1 - 3.4e-18 66.2 0.0 1.8e-16 60.6 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGO21832.1 - 7.3e-05 22.5 0.0 0.0011 18.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGO21832.1 - 0.029 14.3 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF4078 PF13300.6 EGO21832.1 - 0.24 11.7 0.0 0.47 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) IMS PF00817.20 EGO21833.1 - 5.2e-44 149.9 0.1 1.1e-43 148.8 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EGO21833.1 - 1.1e-24 86.7 2.1 2e-24 85.8 2.1 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EGO21833.1 - 2.6e-15 57.2 0.0 1.5e-14 54.7 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EGO21833.1 - 5.3e-10 39.6 0.0 1.3e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 EGO21833.1 - 1.2e-05 25.3 0.0 5.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.26 EGO21833.1 - 3.4e-05 24.1 0.0 8.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGO21833.1 - 0.00024 21.0 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.11 EGO21833.1 - 0.024 15.0 0.0 0.077 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Methyltransf_25 PF13649.6 EGO21834.1 - 1.4e-15 57.7 0.0 2.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO21834.1 - 8.3e-15 55.2 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO21834.1 - 1e-13 51.3 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO21834.1 - 1.5e-13 50.9 0.0 1.9e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO21834.1 - 9.5e-13 48.7 0.0 1.9e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO21834.1 - 2e-06 27.3 0.1 4.3e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EGO21834.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.3 1 1 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EGO21834.1 - 0.01 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGO21834.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EGO21834.1 - 0.032 13.3 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 EGO21834.1 - 0.048 12.6 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF4483 PF14825.6 EGO21834.1 - 0.084 12.6 0.3 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) OPT PF03169.15 EGO21835.1 - 7.5e-194 645.8 55.9 8.9e-194 645.6 55.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Polysacc_lyase PF14099.6 EGO21837.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide lyase DUF4006 PF13179.6 EGO21840.1 - 0.091 12.7 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) TssO PF17561.2 EGO21840.1 - 0.17 12.0 0.0 1.3 9.1 0.0 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO HMG_box PF00505.19 EGO21843.1 - 1.3e-08 35.2 6.6 2.7e-07 30.9 6.6 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO21843.1 - 0.00029 21.4 5.1 0.0014 19.2 5.1 2.0 1 1 0 1 1 1 1 HMG-box domain DUF1691 PF07950.11 EGO21844.1 - 8.9e-06 26.4 2.9 0.0041 17.8 1.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) DUF4203 PF13886.6 EGO21844.1 - 0.052 13.2 1.8 0.71 9.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) 2OG-FeII_Oxy_3 PF13640.6 EGO21845.1 - 3.2e-08 34.4 0.0 1.3e-07 32.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MSA-2c PF12238.8 EGO21845.1 - 2 8.4 3.5 4.1 7.4 3.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Cerato-platanin PF07249.12 EGO21846.1 - 1.9e-38 131.2 1.4 2.3e-38 131.0 1.4 1.1 1 0 0 1 1 1 1 Cerato-platanin MFS18 PF17352.2 EGO21846.1 - 0.075 13.4 0.4 0.11 12.8 0.4 1.3 1 0 0 1 1 1 0 Male Flower Specific protein 18 Cerato-platanin PF07249.12 EGO21848.1 - 6.6e-42 142.4 1.7 7.8e-42 142.2 1.7 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 EGO21849.1 - 1.8e-38 131.3 1.0 2.4e-38 130.9 1.0 1.2 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 EGO21851.1 - 3.8e-40 136.7 2.4 4.4e-40 136.5 2.4 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 EGO21852.1 - 1.1e-08 35.2 0.1 1.5e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EGO21852.1 - 0.0024 17.7 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Barwin family AMP-binding PF00501.28 EGO21853.1 - 1.1e-58 198.9 0.0 1.4e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO21853.1 - 1e-12 48.9 1.7 3.5e-12 47.1 1.7 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain S-methyl_trans PF02574.16 EGO21853.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase GST_N_3 PF13417.6 EGO21854.1 - 2.8e-10 40.4 0.0 1.1e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO21854.1 - 3.1e-08 33.8 0.0 5.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO21854.1 - 0.0016 18.6 0.0 0.0035 17.5 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO21854.1 - 0.0048 17.2 0.0 0.025 14.9 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO21854.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO21855.1 - 1.3e-05 25.4 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO21855.1 - 1.8e-05 25.0 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO21855.1 - 7e-05 23.0 0.0 0.00012 22.2 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO21855.1 - 7.2e-05 23.1 0.1 0.00015 22.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO21855.1 - 0.0036 17.3 0.4 0.0081 16.2 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Rrp15p PF07890.12 EGO21856.1 - 8.4e-23 81.2 5.2 1.4e-22 80.5 5.2 1.4 1 1 0 1 1 1 1 Rrp15p Glyco_hydro_3_C PF01915.22 EGO21859.1 - 1.6e-61 207.9 0.0 2.5e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO21859.1 - 9.8e-46 156.6 0.0 3.3e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO21859.1 - 2.9e-22 78.6 0.4 8.4e-22 77.1 0.4 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EGO21859.1 - 7.2e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain NAD_binding_2 PF03446.15 EGO21860.1 - 3.6e-23 82.5 0.0 4.6e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGO21860.1 - 1.1e-06 28.8 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGO21860.1 - 4e-06 27.3 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 EGO21860.1 - 0.0013 19.4 0.0 0.0019 18.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EGO21860.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EGO21860.1 - 0.025 15.4 0.0 0.037 14.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 EGO21860.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ABC_tran PF00005.27 EGO21861.1 - 3.7e-34 118.2 0.0 1.2e-33 116.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EGO21861.1 - 5.7e-32 111.5 11.5 7.5e-32 111.1 11.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EGO21861.1 - 7.1e-06 26.0 0.5 0.036 13.9 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO21861.1 - 0.00046 19.9 0.1 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO21861.1 - 0.0032 17.8 0.2 0.0078 16.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGO21861.1 - 0.0035 16.6 0.0 0.0076 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 EGO21861.1 - 0.0048 17.4 0.0 0.0081 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGO21861.1 - 0.0098 16.0 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 EGO21861.1 - 0.012 15.7 0.3 0.026 14.6 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 EGO21861.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO21861.1 - 0.032 14.5 0.2 0.12 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGO21861.1 - 0.034 13.2 0.1 0.076 12.1 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 EGO21861.1 - 0.04 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGO21861.1 - 0.042 13.8 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Secretin PF00263.21 EGO21861.1 - 0.045 13.4 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein SMC_N PF02463.19 EGO21861.1 - 0.048 13.1 0.0 2.7 7.4 0.1 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EGO21861.1 - 0.054 13.5 0.1 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EGO21861.1 - 0.058 13.2 0.2 1.2 8.9 0.2 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 EGO21861.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 EGO21861.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 EGO21861.1 - 0.15 12.0 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 NTPase cobW PF02492.19 EGO21861.1 - 0.24 10.9 0.7 1.9 8.1 0.2 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.28 EGO21863.1 - 0.092 11.3 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme AMP-binding PF00501.28 EGO21864.1 - 0.07 11.7 0.0 0.07 11.7 0.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme DUF4224 PF13986.6 EGO21864.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) SRTM1 PF15872.5 EGO21870.1 - 0.25 11.5 3.5 0.88 9.7 0.8 2.4 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 AMP-binding PF00501.28 EGO21872.1 - 1.2e-91 307.4 0.0 1.8e-91 306.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGO21872.1 - 1.4e-57 195.2 0.1 4.1e-57 193.6 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EGO21872.1 - 1.4e-56 192.1 0.0 2.2e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EGO21872.1 - 2.1e-35 122.2 0.1 5.8e-35 120.8 0.1 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EGO21872.1 - 1.5e-33 116.7 0.0 2.7e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGO21872.1 - 1e-30 106.1 0.4 1.4e-29 102.5 0.2 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EGO21872.1 - 6.7e-22 78.1 0.0 1.9e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EGO21872.1 - 1.2e-18 67.2 1.7 1.1e-09 38.5 0.0 3.6 4 0 0 4 4 3 2 Phosphopantetheine attachment site Thioesterase PF00975.20 EGO21872.1 - 2.4e-17 63.9 0.0 4.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EGO21872.1 - 1.7e-09 38.1 0.1 5.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 EGO21872.1 - 5.8e-08 33.6 0.1 1.9e-07 32.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 EGO21872.1 - 0.00027 20.4 0.3 0.00074 18.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 EGO21872.1 - 0.0029 17.6 0.1 0.16 11.9 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 EGO21872.1 - 0.0056 16.5 2.4 0.0063 16.3 0.4 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hydrolase_4 PF12146.8 EGO21872.1 - 0.0067 15.7 0.1 0.11 11.8 0.0 2.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO21872.1 - 0.009 16.6 0.1 0.11 13.1 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family LRR_4 PF12799.7 EGO21873.1 - 2.3e-07 31.0 8.0 0.12 12.8 0.0 6.8 4 3 4 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGO21873.1 - 0.0023 17.8 15.5 0.37 11.0 0.1 6.6 8 0 0 8 8 8 2 Leucine Rich repeat Zn_Tnp_IS1595 PF12760.7 EGO21873.1 - 0.024 14.6 0.1 0.054 13.5 0.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain LRR_1 PF00560.33 EGO21873.1 - 0.12 13.0 3.8 1.4e+02 3.7 0.0 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 EGO21873.1 - 0.79 9.5 9.2 17 5.3 0.0 5.5 4 2 1 5 5 5 0 Leucine rich repeat FMO-like PF00743.19 EGO21874.1 - 1.4e-15 56.8 0.1 3.3e-14 52.2 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGO21874.1 - 5e-11 42.7 0.2 1.2e-10 41.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO21874.1 - 1e-09 38.1 0.0 3.8e-07 29.6 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO21874.1 - 1.7e-07 30.7 0.0 3.8e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGO21874.1 - 3.5e-07 29.8 0.8 6.6e-06 25.6 0.5 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO21874.1 - 9.7e-07 28.7 0.0 6.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO21874.1 - 0.00018 21.5 0.4 0.0012 18.8 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGO21874.1 - 0.077 12.1 0.5 0.11 11.5 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EGO21874.1 - 0.087 13.4 0.2 0.087 13.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO21874.1 - 0.22 10.7 0.8 0.7 9.1 0.2 2.1 4 0 0 4 4 4 0 Thi4 family FMO-like PF00743.19 EGO21875.1 - 3.4e-15 55.5 0.6 1.9e-13 49.7 0.7 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO21875.1 - 5.2e-11 42.4 0.2 5e-09 35.8 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO21875.1 - 1.1e-10 41.3 0.0 2.3e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO21875.1 - 1.9e-09 37.6 0.1 5.2e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGO21875.1 - 8.3e-08 31.7 0.2 1.1e-06 28.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EGO21875.1 - 2.4e-05 23.6 0.5 0.045 12.8 1.2 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 EGO21875.1 - 0.00028 20.6 1.4 0.0031 17.1 0.7 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO21875.1 - 0.0045 16.3 1.1 0.0067 15.7 0.3 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EGO21875.1 - 0.1 11.6 0.8 3.8 6.5 0.4 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A Eno-Rase_NADH_b PF12242.8 EGO21875.1 - 0.15 11.9 0.1 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_25 PF01183.20 EGO21876.1 - 5.8e-52 176.4 1.9 6.8e-52 176.2 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 FAD_oxidored PF12831.7 EGO21877.1 - 0.0028 17.1 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO21877.1 - 0.0036 16.2 0.0 0.039 12.8 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Thaumatin PF00314.17 EGO21878.1 - 7e-13 48.7 12.6 9.2e-13 48.3 12.6 1.2 1 0 0 1 1 1 1 Thaumatin family RBD PF02196.15 EGO21879.1 - 0.076 13.1 0.2 0.099 12.7 0.2 1.2 1 0 0 1 1 1 0 Raf-like Ras-binding domain FAD_oxidored PF12831.7 EGO21880.1 - 0.00088 18.7 0.0 0.0061 16.0 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO21880.1 - 0.001 18.0 0.2 3.2 6.5 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGO21880.1 - 0.037 13.3 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0227 PF05728.12 EGO21881.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 EGO21881.1 - 0.028 13.9 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pyr_redox_2 PF07992.14 EGO21881.1 - 0.08 12.2 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO21881.1 - 0.088 12.1 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO21882.1 - 0.028 13.3 0.0 4.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 EGO21882.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO21882.1 - 0.19 11.0 0.0 5.6 6.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain eIF2A PF08662.11 EGO21883.1 - 1.1e-78 263.6 0.0 2.6e-77 259.1 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EGO21883.1 - 0.067 14.1 0.1 1.8 9.6 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 EGO21883.1 - 0.4 10.4 3.5 75 3.1 0.0 3.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDV3 PF15359.6 EGO21883.1 - 5.4 7.5 8.2 0.25 11.8 1.9 2.0 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Cellulase PF00150.18 EGO21884.1 - 2.3e-13 50.2 0.0 1e-09 38.2 0.1 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGO21884.1 - 6e-07 29.9 0.0 3.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 EGO21884.1 - 0.0071 16.0 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Dimer_Tnp_Tn5 PF02281.16 EGO21884.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain OPA3 PF07047.12 EGO21885.1 - 1.7e-43 147.4 0.2 1.7e-43 147.4 0.2 1.4 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) CLZ PF16526.5 EGO21885.1 - 0.0099 16.2 1.0 0.022 15.1 1.0 1.5 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 EGO21885.1 - 0.59 8.6 2.9 0.83 8.1 2.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family CDC73_C PF05179.14 EGO21886.1 - 1.6e-52 177.4 0.3 2.4e-52 176.8 0.3 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal GST_N_2 PF13409.6 EGO21887.1 - 4.7e-09 36.4 0.0 8.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO21887.1 - 7.7e-09 35.8 0.0 2.7e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO21887.1 - 7.9e-05 22.8 0.1 0.00024 21.2 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO21887.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO21887.1 - 0.00034 20.6 0.1 0.00076 19.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO21887.1 - 0.0041 17.4 0.0 0.028 14.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGO21887.1 - 0.16 12.8 0.0 0.28 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EGO21888.1 - 1.7e-06 28.2 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO21888.1 - 2.2e-06 28.0 0.0 1e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO21888.1 - 0.00014 22.0 0.0 0.0004 20.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO21888.1 - 0.00024 21.1 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO21888.1 - 0.00033 20.8 0.0 0.0007 19.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO21889.1 - 1.1e-05 25.5 0.1 1.7e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO21889.1 - 3e-05 24.1 0.0 4.2e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO21889.1 - 0.0011 18.9 0.1 0.0017 18.3 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.28 EGO21890.1 - 1.1e-30 106.6 0.0 4.1e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme ZapB PF06005.12 EGO21891.1 - 0.00018 21.8 4.5 0.00018 21.8 4.5 2.0 1 1 1 2 2 2 1 Cell division protein ZapB DUF2514 PF10721.9 EGO21891.1 - 0.0094 16.0 0.3 0.01 15.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Jnk-SapK_ap_N PF09744.9 EGO21891.1 - 0.025 14.8 6.3 0.029 14.6 6.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PHM7_cyt PF14703.6 EGO21891.1 - 0.034 14.4 0.3 0.044 14.0 0.3 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DivIC PF04977.15 EGO21891.1 - 0.073 12.8 3.5 0.064 13.0 1.9 1.8 1 1 1 2 2 2 0 Septum formation initiator betaPIX_CC PF16523.5 EGO21891.1 - 0.079 12.8 5.8 0.11 12.4 5.8 1.3 1 1 0 1 1 1 0 betaPIX coiled coil APG6_N PF17675.1 EGO21891.1 - 0.1 13.1 9.2 0.17 12.4 9.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EGO21891.1 - 0.17 11.9 10.9 1.7 8.6 1.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 EGO21891.1 - 0.25 11.8 5.1 0.31 11.6 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prominin PF05478.11 EGO21891.1 - 0.48 8.3 4.7 0.48 8.3 4.7 1.0 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.8 EGO21891.1 - 0.59 10.2 10.7 0.96 9.5 10.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 EGO21891.1 - 0.79 10.4 5.9 1.2 9.8 5.9 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Aldolase_II PF00596.21 EGO21892.1 - 5.2e-40 137.4 0.0 6.1e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.25 EGO21893.1 - 4.1e-38 131.3 0.0 5.4e-19 68.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21893.1 - 1.6e-14 53.8 0.4 6.4e-07 28.9 0.1 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGO21893.1 - 0.3 10.0 0.1 0.44 9.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Asp PF00026.23 EGO21894.1 - 4.2e-77 259.7 5.0 4.7e-77 259.5 5.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO21894.1 - 7.3e-08 32.9 6.0 0.0017 18.6 0.3 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Mg_trans_NIPA PF05653.14 EGO21895.1 - 3.6e-17 62.4 12.1 5.7e-11 42.1 0.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF3185 PF11381.8 EGO21895.1 - 0.084 12.9 5.2 18 5.5 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF4201 PF13870.6 EGO21896.1 - 0.0075 16.0 24.2 0.077 12.7 14.6 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4201) Spc7 PF08317.11 EGO21896.1 - 0.072 12.0 25.8 0.056 12.3 16.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4472 PF14739.6 EGO21896.1 - 0.1 13.3 23.4 0.55 11.0 2.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) CALCOCO1 PF07888.11 EGO21896.1 - 0.21 10.4 27.7 0.41 9.5 19.1 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Frankia_peptide PF14407.6 EGO21896.1 - 0.27 11.3 3.4 0.33 11.0 0.4 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Rootletin PF15035.6 EGO21896.1 - 0.46 10.5 27.0 1.1 9.3 18.7 2.8 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 EGO21896.1 - 0.62 10.7 20.4 0.2 12.3 3.7 3.6 2 1 1 3 3 3 0 Initiation control protein YabA DUF4164 PF13747.6 EGO21896.1 - 0.69 10.2 18.1 0.22 11.8 3.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF5082 PF16888.5 EGO21896.1 - 0.85 9.9 20.5 3.2 8.1 1.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 EGO21896.1 - 1.5 9.4 41.1 0.093 13.3 10.8 3.5 3 1 1 4 4 4 0 Apg6 coiled-coil region AATF-Che1 PF13339.6 EGO21896.1 - 3.8 8.2 25.8 69 4.1 16.4 3.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF5621 PF18532.1 EGO21896.1 - 5.3 6.9 9.3 15 5.5 1.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5621) SlyX PF04102.12 EGO21896.1 - 7.3 7.3 23.4 4.8 7.9 1.7 3.9 2 1 1 3 3 3 0 SlyX MCC-bdg_PDZ PF10506.9 EGO21896.1 - 7.7 6.6 17.4 1.9 8.5 0.7 3.5 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ADIP PF11559.8 EGO21896.1 - 7.9 6.5 31.1 5.1 7.2 8.6 3.4 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 EGO21896.1 - 8.9 6.0 36.3 0.16 11.8 21.4 2.9 3 1 0 3 3 3 0 Ezrin/radixin/moesin family O-FucT PF10250.9 EGO21897.1 - 1.1e-14 54.9 0.0 4.8e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase UDPGT PF00201.18 EGO21898.1 - 0.0031 16.4 0.1 0.0039 16.1 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGO21898.1 - 0.013 15.5 0.1 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Hist_deacetyl PF00850.19 EGO21900.1 - 5.8e-82 275.6 0.1 7.1e-82 275.3 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ELH PF02323.15 EGO21900.1 - 0.098 12.0 3.1 0.15 11.4 3.1 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor Per1 PF04080.13 EGO21901.1 - 2.3e-99 332.3 13.1 2.7e-99 332.1 13.1 1.1 1 0 0 1 1 1 1 Per1-like family DPCD PF14913.6 EGO21902.1 - 0.087 12.2 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 DPCD protein family Pribosyltran_N PF13793.6 EGO21903.1 - 4.6e-51 171.7 0.1 1.5e-49 166.7 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGO21903.1 - 4.3e-35 121.4 0.6 1.2e-30 106.9 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGO21903.1 - 1.9e-17 63.2 0.2 2.8e-15 56.2 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO21903.1 - 0.00069 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_kinase PF00696.28 EGO21904.1 - 1e-39 136.6 0.8 1.5e-39 136.0 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EGO21904.1 - 9.4e-09 35.1 0.0 0.00051 19.9 0.0 2.6 2 0 0 2 2 2 2 PUA domain Cupin_2 PF07883.11 EGO21905.1 - 2.4e-07 30.3 0.5 5e-07 29.4 0.5 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGO21905.1 - 0.022 14.7 0.1 0.065 13.1 0.1 1.7 1 1 1 2 2 2 0 AraC-like ligand binding domain Cupin_1 PF00190.22 EGO21905.1 - 0.061 12.9 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin DOPA_dioxygen PF08883.11 EGO21906.1 - 1e-30 106.1 0.0 1.3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glycos_transf_1 PF00534.20 EGO21907.1 - 6.3e-21 74.7 0.0 1.7e-11 44.0 0.0 2.5 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO21907.1 - 6e-18 65.4 0.1 1.3e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGO21907.1 - 1.3e-07 32.2 0.0 2.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EGO21907.1 - 3.1e-07 30.9 0.0 5.3e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Ccdc124 PF06244.12 EGO21911.1 - 4.1e-20 72.6 32.5 6.5e-17 62.3 2.0 3.2 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 Borrelia_P83 PF05262.11 EGO21911.1 - 1.4 7.3 13.9 2.2 6.7 13.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 EGO21911.1 - 4.7 5.9 7.3 6.2 5.5 7.3 1.2 1 0 0 1 1 1 0 Presenilin Lipase_GDSL PF00657.22 EGO21912.1 - 5e-11 42.9 0.0 6.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGO21912.1 - 5.5e-08 33.4 0.4 1.8e-07 31.7 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family NACHT PF05729.12 EGO21913.1 - 8.9e-05 22.5 0.0 0.00028 20.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO21913.1 - 0.00021 21.7 0.0 0.00048 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGO21913.1 - 0.021 15.4 0.0 0.21 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGO21913.1 - 0.062 12.5 0.2 0.22 10.7 0.2 1.8 1 1 1 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 EGO21913.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase HET PF06985.11 EGO21914.1 - 2e-26 93.1 0.0 3.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Calcipressin PF04847.12 EGO21915.1 - 2.2e-29 102.5 0.0 2.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Calcipressin STE2 PF02116.15 EGO21917.1 - 0.04 13.2 6.9 0.12 11.7 7.0 1.5 1 1 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR Pkinase PF00069.25 EGO21918.1 - 7.2e-31 107.5 0.0 3.1e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21918.1 - 7.2e-15 55.0 0.0 5.7e-13 48.7 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO21918.1 - 7.3e-05 22.2 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGO21918.1 - 0.00064 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO21918.1 - 0.0094 15.9 0.4 0.053 13.4 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO21918.1 - 0.037 12.8 0.0 0.064 12.0 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGO21918.1 - 0.51 9.2 0.0 0.51 9.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain DUF4233 PF14017.6 EGO21923.1 - 0.00091 19.5 2.8 0.59 10.5 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4233) COX17 PF05051.13 EGO21924.1 - 4.9e-21 74.8 3.5 6.5e-21 74.4 3.5 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) WD40 PF00400.32 EGO21925.1 - 1.9e-11 44.3 5.4 1.6e-08 35.1 0.2 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21925.1 - 6e-09 36.1 0.0 0.00095 19.4 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGO21925.1 - 0.031 13.2 0.1 0.071 12.0 0.0 1.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 EGO21925.1 - 0.085 12.2 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 EGO21926.1 - 1.4e-16 60.5 2.0 2.6e-08 34.4 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO21926.1 - 2.6e-08 34.0 0.2 1e-05 25.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 EGO21926.1 - 0.012 15.9 2.0 0.061 13.7 1.8 2.2 2 0 0 2 2 2 0 Ring finger domain HOOK PF05622.12 EGO21926.1 - 0.014 13.6 4.9 0.018 13.2 4.9 1.1 1 0 0 1 1 1 0 HOOK protein zf-C3HC4_2 PF13923.6 EGO21926.1 - 0.014 15.2 1.3 0.014 15.2 1.3 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Ge1_WD40 PF16529.5 EGO21926.1 - 0.023 13.7 0.0 0.056 12.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1272 PF06906.11 EGO21926.1 - 0.033 14.3 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 EGO21926.1 - 0.058 13.3 3.3 0.16 11.8 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fmp27_WPPW PF10359.9 EGO21926.1 - 0.073 11.9 3.4 0.1 11.5 3.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-RING_10 PF16685.5 EGO21926.1 - 0.083 13.0 0.4 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Beta_helix_2 PF18835.1 EGO21926.1 - 0.094 12.5 0.8 6.9 6.5 0.0 2.9 1 1 1 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-RING_5 PF14634.6 EGO21926.1 - 0.11 12.5 3.7 0.48 10.4 3.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 EGO21926.1 - 0.12 11.8 0.6 0.29 10.6 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain APG6_N PF17675.1 EGO21926.1 - 0.29 11.6 5.6 0.43 11.1 5.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 EGO21926.1 - 0.3 10.7 5.5 0.47 10.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spectrin PF00435.21 EGO21926.1 - 0.51 10.8 4.8 0.92 10.0 4.8 1.3 1 0 0 1 1 1 0 Spectrin repeat TackOD1 PF18551.1 EGO21926.1 - 3.1 7.4 5.5 0.24 11.0 0.1 1.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 EF-hand_4 PF12763.7 EGO21927.1 - 1.1e-13 51.1 0.0 1e-08 35.0 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand ATP-synt_DE PF00401.20 EGO21929.1 - 0.026 14.8 1.1 0.049 13.9 1.1 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Glyoxalase_3 PF13468.6 EGO21933.1 - 2.1e-30 106.2 0.0 1.1e-29 103.7 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Asp PF00026.23 EGO21934.1 - 4.3e-44 151.2 5.5 4.5e-32 111.7 0.2 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGO21934.1 - 0.00084 19.1 0.0 0.0024 17.7 0.0 1.8 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 EGO21935.1 - 2.6e-78 263.6 4.6 3.1e-78 263.4 4.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGO21935.1 - 4.4e-05 23.3 0.0 9.7e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGO21935.1 - 0.00059 20.1 1.9 0.093 13.0 1.9 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal CCDC144C PF14915.6 EGO21936.1 - 0.0005 19.3 9.2 0.00075 18.7 9.2 1.3 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region ZapB PF06005.12 EGO21936.1 - 0.0018 18.7 12.7 0.16 12.5 6.5 2.9 2 1 1 3 3 2 2 Cell division protein ZapB RasGAP_C PF03836.15 EGO21936.1 - 0.0031 17.6 4.1 0.039 14.1 1.7 2.2 1 1 1 2 2 2 1 RasGAP C-terminus APG6_N PF17675.1 EGO21936.1 - 0.0054 17.3 13.9 8.7 6.9 14.3 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Syntaxin_2 PF14523.6 EGO21936.1 - 0.0072 16.7 3.0 1 9.8 0.0 2.4 1 1 1 2 2 2 1 Syntaxin-like protein CENP-F_leu_zip PF10473.9 EGO21936.1 - 0.0074 16.3 10.6 0.039 14.0 9.9 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 EGO21936.1 - 0.0099 15.7 10.3 0.029 14.2 9.4 2.0 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH CdvA PF18822.1 EGO21936.1 - 0.013 15.3 7.9 0.12 12.2 4.9 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain YabA PF06156.13 EGO21936.1 - 0.029 15.0 8.6 0.29 11.8 7.0 2.8 1 1 1 2 2 2 0 Initiation control protein YabA GAS PF13851.6 EGO21936.1 - 0.041 13.2 11.1 0.52 9.6 1.8 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 EGO21936.1 - 0.045 11.9 9.2 0.021 13.0 1.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF3584 PF12128.8 EGO21936.1 - 0.051 11.1 10.3 0.061 10.9 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 EGO21936.1 - 0.051 14.0 11.9 0.27 11.7 11.9 2.0 1 1 0 1 1 1 0 Fez1 DUF3450 PF11932.8 EGO21936.1 - 0.064 12.6 9.4 0.043 13.1 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 EGO21936.1 - 0.07 13.2 19.4 0.058 13.5 3.1 3.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMF_TATA_bd PF12325.8 EGO21936.1 - 0.076 13.2 11.8 0.094 12.9 5.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TACC_C PF05010.14 EGO21936.1 - 0.085 12.6 9.1 0.66 9.7 3.5 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DegS PF05384.11 EGO21936.1 - 0.087 12.3 8.7 0.029 13.9 3.5 2.2 1 1 1 2 2 2 0 Sensor protein DegS CLZ PF16526.5 EGO21936.1 - 0.089 13.2 0.6 0.089 13.2 0.6 2.4 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Seryl_tRNA_N PF02403.22 EGO21936.1 - 0.12 12.6 6.7 0.26 11.5 3.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Taxilin PF09728.9 EGO21936.1 - 0.13 11.4 10.0 0.18 10.9 10.0 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Occludin_ELL PF07303.13 EGO21936.1 - 0.23 12.2 8.2 4.7 8.0 1.5 2.9 1 1 0 2 2 2 0 Occludin homology domain DUF2205 PF10224.9 EGO21936.1 - 0.24 11.4 6.7 0.56 10.2 1.4 3.1 1 1 1 2 2 2 0 Short coiled-coil protein APC_N_CC PF16689.5 EGO21936.1 - 0.24 11.5 5.0 0.62 10.2 0.3 3.2 4 0 0 4 4 3 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1664 PF07889.12 EGO21936.1 - 0.26 11.4 4.2 1.2 9.2 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGO21936.1 - 0.33 11.3 5.1 1.2 9.5 1.3 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EGO21936.1 - 0.34 9.8 11.2 0.68 8.8 11.2 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4530 PF15039.6 EGO21936.1 - 0.39 10.9 4.7 0.21 11.8 1.3 2.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4530) IFP_35_N PF07334.13 EGO21936.1 - 0.56 10.3 2.7 9.3 6.4 0.2 2.6 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Bap31_Bap29_C PF18035.1 EGO21936.1 - 0.61 10.1 5.4 1 9.5 0.9 3.2 2 2 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FUSC PF04632.12 EGO21936.1 - 0.62 8.5 9.7 0.77 8.2 9.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRKG1_interact PF15898.5 EGO21936.1 - 0.63 11.0 12.9 0.47 11.4 4.0 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TMF_DNA_bd PF12329.8 EGO21936.1 - 0.66 10.0 6.3 2.3 8.3 0.9 2.8 2 1 0 3 3 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 EGO21936.1 - 0.81 10.0 8.8 0.98 9.8 3.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EGO21936.1 - 0.92 8.8 7.0 1.8 7.8 7.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 EGO21936.1 - 1.1 8.9 8.3 22 4.6 8.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 EGO21936.1 - 1.2 8.3 7.7 1.4 8.1 1.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 EGO21936.1 - 1.4 8.7 10.4 0.9 9.3 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DASH_Hsk3 PF08227.11 EGO21936.1 - 1.5 9.3 9.1 5.4 7.5 1.2 3.4 4 0 0 4 4 3 0 DASH complex subunit Hsk3 like T2SSF PF00482.23 EGO21936.1 - 1.5 8.8 4.4 5 7.1 1.3 2.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F EMP24_GP25L PF01105.24 EGO21936.1 - 3.9 7.4 5.3 22 4.9 3.0 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD THOC7 PF05615.13 EGO21936.1 - 5.9 7.2 12.3 10 6.4 0.3 3.1 1 1 1 2 2 2 0 Tho complex subunit 7 UPF0242 PF06785.11 EGO21936.1 - 6.6 6.8 11.7 96 3.0 11.7 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EGO21936.1 - 9.2 6.7 10.4 1e+02 3.3 10.5 2.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Ada3 PF10198.9 EGO21937.1 - 3.5e-26 91.9 0.0 3.5e-26 91.9 0.0 2.8 4 0 0 4 4 4 1 Histone acetyltransferases subunit 3 DUF5482 PF17579.2 EGO21937.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5482) Herpes_UL25 PF01499.16 EGO21937.1 - 0.13 10.8 0.2 0.21 10.1 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family MgtE PF01769.16 EGO21938.1 - 8.8e-43 145.6 13.3 3.3e-24 85.7 5.7 3.4 2 1 1 3 3 3 2 Divalent cation transporter RNA_polI_A34 PF08208.11 EGO21940.1 - 1.2e-17 64.7 7.6 1.2e-17 64.7 7.6 2.8 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Phos_pyr_kin PF08543.12 EGO21941.1 - 7.2e-85 284.3 0.1 1.4e-83 280.0 0.1 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EGO21941.1 - 3.1e-37 128.4 0.1 4.4e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EGO21941.1 - 0.00025 20.5 0.0 0.08 12.2 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HhH-GPD PF00730.25 EGO21942.1 - 2.6e-21 76.1 0.0 4.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGO21942.1 - 6.7e-08 32.0 0.0 1.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGO21942.1 - 0.022 15.4 0.1 1 10.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain RseC_MucC PF04246.12 EGO21942.1 - 0.042 13.8 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC STE2 PF02116.15 EGO21943.1 - 0.0031 16.9 0.6 0.0031 16.9 0.6 2.2 2 0 0 2 2 2 2 Fungal pheromone mating factor STE2 GPCR 3Beta_HSD PF01073.19 EGO21944.1 - 1.2e-66 224.6 0.0 1.5e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO21944.1 - 2.3e-30 105.9 0.0 3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO21944.1 - 1.3e-15 57.7 0.0 2e-12 47.2 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO21944.1 - 1.9e-14 53.5 0.0 2.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGO21944.1 - 2e-12 47.4 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO21944.1 - 3.6e-08 32.9 0.2 1.1e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGO21944.1 - 4e-07 29.5 0.1 3.2e-06 26.5 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EGO21944.1 - 3e-05 24.0 0.9 0.00066 19.6 0.9 2.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EGO21944.1 - 0.035 13.7 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 EGO21944.1 - 0.044 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Mak10 PF04112.13 EGO21945.1 - 1.2e-52 177.9 0.0 2e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.25 EGO21946.1 - 2e-72 244.0 0.0 2.5e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TFB6 PF17110.5 EGO21947.1 - 7e-05 22.6 0.2 0.00028 20.7 0.2 1.8 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH MRP-S33 PF08293.11 EGO21948.1 - 5.7e-29 100.2 0.6 7e-29 99.9 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SUV3_C PF12513.8 EGO21950.1 - 2.3e-14 53.0 0.5 2.3e-14 53.0 0.5 2.1 3 0 0 3 3 3 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EGO21950.1 - 9.5e-10 38.8 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EGO21950.1 - 7.6e-05 22.5 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 EGO21950.1 - 0.013 15.7 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) p450 PF00067.22 EGO21951.1 - 3.8e-09 35.8 0.0 7.9e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 EGO21952.1 - 4.4e-06 26.9 0.0 8.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO21952.1 - 0.00024 21.4 0.0 0.00034 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO21952.1 - 0.00061 19.7 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGO21952.1 - 0.016 15.2 0.1 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase VHL_C PF17211.3 EGO21952.1 - 0.14 12.2 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 VHL box domain adh_short PF00106.25 EGO21954.1 - 1.1e-46 158.8 1.4 7.9e-46 156.0 1.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO21954.1 - 1.8e-39 135.7 0.1 3.3e-39 134.8 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO21954.1 - 9.5e-09 35.4 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EGO21954.1 - 0.0004 20.9 0.6 0.0008 19.9 0.6 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 EGO21954.1 - 0.0053 16.1 0.1 0.0084 15.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 EGO21954.1 - 0.0068 15.6 0.1 0.0095 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EGO21954.1 - 0.0075 16.2 0.2 0.011 15.7 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGO21954.1 - 0.024 14.7 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EGO21954.1 - 0.031 13.7 0.1 0.083 12.3 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EGO21954.1 - 0.037 14.1 0.6 0.078 13.0 0.6 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGO21954.1 - 0.044 14.1 0.2 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4971 PF16341.5 EGO21954.1 - 0.052 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) IPK PF03770.16 EGO21956.1 - 2.3e-43 148.4 0.0 2.9e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CENP-B_dimeris PF09026.10 EGO21956.1 - 0.023 15.1 7.7 0.038 14.4 7.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rhabdo_ncap PF00945.18 EGO21956.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein p450 PF00067.22 EGO21957.1 - 5.2e-42 144.2 0.0 6.8e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.19 EGO21958.1 - 1e-27 96.9 0.0 5.6e-27 94.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO21958.1 - 9.5e-11 41.6 0.0 2.9e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO21958.1 - 1.8e-09 37.1 0.0 1.1e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EGO21958.1 - 3.9e-06 26.9 0.0 8.2e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO21958.1 - 0.00015 21.8 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO21958.1 - 0.00029 20.1 0.0 0.008 15.3 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGO21958.1 - 0.0072 16.6 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EGO21958.1 - 0.01 15.3 0.0 0.038 13.4 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ABC_membrane PF00664.23 EGO21959.1 - 1.1e-97 327.0 30.1 1.1e-49 169.6 4.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO21959.1 - 1.6e-65 219.8 0.0 5.7e-32 111.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO21959.1 - 1.6e-14 53.9 1.3 8.9e-05 22.0 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO21959.1 - 3.9e-08 32.9 0.8 0.0058 16.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EGO21959.1 - 5.4e-07 28.8 1.4 0.0015 17.4 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EGO21959.1 - 6.3e-07 29.4 0.0 0.0023 17.7 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 EGO21959.1 - 1.7e-06 28.5 0.1 0.06 13.7 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO21959.1 - 6.9e-06 26.1 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGO21959.1 - 2.2e-05 24.8 0.2 0.72 10.1 0.1 4.0 3 2 0 3 3 2 2 AAA domain G-alpha PF00503.20 EGO21959.1 - 7.3e-05 22.1 0.0 0.072 12.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 EGO21959.1 - 0.00014 21.6 0.0 0.2 11.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EGO21959.1 - 0.00023 21.1 1.3 0.068 13.0 0.1 3.6 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO21959.1 - 0.00078 20.0 0.4 0.53 10.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO21959.1 - 0.0027 17.9 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGO21959.1 - 0.0038 16.8 0.6 1.2 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EGO21959.1 - 0.0042 16.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 EGO21959.1 - 0.0053 16.9 2.0 0.35 10.9 0.0 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 EGO21959.1 - 0.0064 16.7 7.6 0.81 10.0 0.7 4.1 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EGO21959.1 - 0.01 15.1 0.0 3.7 6.8 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin AAA_18 PF13238.6 EGO21959.1 - 0.021 15.4 0.0 6.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGO21959.1 - 0.021 14.8 0.0 9.6 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGO21959.1 - 0.022 15.2 0.0 8.9 6.8 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.17 EGO21959.1 - 0.08 12.7 0.1 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGO21959.1 - 0.086 12.9 0.3 16 5.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rax2 PF12768.7 EGO21959.1 - 0.11 11.9 1.2 0.47 9.9 0.1 2.3 2 0 0 2 2 2 0 Cortical protein marker for cell polarity APS_kinase PF01583.20 EGO21959.1 - 0.11 12.3 0.0 29 4.5 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase 3Beta_HSD PF01073.19 EGO21960.1 - 1e-27 96.9 0.0 5.6e-27 94.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO21960.1 - 9.5e-11 41.6 0.0 2.9e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO21960.1 - 1.8e-09 37.1 0.0 1.1e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EGO21960.1 - 3.9e-06 26.9 0.0 8.2e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO21960.1 - 0.00015 21.8 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO21960.1 - 0.00029 20.1 0.0 0.008 15.3 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGO21960.1 - 0.0072 16.6 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EGO21960.1 - 0.01 15.3 0.0 0.038 13.4 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Retrotrans_gag PF03732.17 EGO21964.1 - 2.6e-07 30.8 1.2 6.3e-07 29.6 0.4 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO21964.1 - 8.5e-07 28.8 3.7 1.7e-06 27.8 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 EGO21964.1 - 0.042 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Glycos_trans_3N PF02885.17 EGO21964.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain zf-CCHC_5 PF14787.6 EGO21964.1 - 0.23 11.2 1.3 0.48 10.2 1.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Helicase_C PF00271.31 EGO21966.1 - 3.6e-15 56.3 0.0 8.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO21966.1 - 5.4e-06 26.3 0.0 0.00092 19.0 0.2 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGO21966.1 - 0.0014 17.9 0.7 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase T4SS-DNA_transf PF02534.14 EGO21966.1 - 0.0018 17.1 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Osteopontin PF00865.18 EGO21967.1 - 0.011 15.3 2.2 0.013 15.0 2.2 1.2 1 0 0 1 1 1 0 Osteopontin RhoGEF PF00621.20 EGO21969.1 - 3.4e-42 144.7 2.2 5.3e-42 144.1 2.2 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 EGO21969.1 - 5.9e-20 70.6 0.9 3.5e-11 42.5 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EGO21969.1 - 5.2e-19 67.8 2.0 2e-09 37.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 EGO21969.1 - 6.9e-13 48.7 0.0 3.6e-07 30.1 0.1 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain SH3_2 PF07653.17 EGO21969.1 - 1.3e-11 44.0 0.0 4.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PH PF00169.29 EGO21969.1 - 0.0005 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 PH domain YL1 PF05764.13 EGO21969.1 - 0.0024 18.0 3.1 0.0042 17.2 3.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein PH_16 PF17838.1 EGO21969.1 - 0.021 14.7 0.0 0.064 13.1 0.0 1.8 1 1 0 1 1 1 0 PH domain BUD22 PF09073.10 EGO21969.1 - 0.16 11.3 4.8 0.29 10.4 4.8 1.3 1 0 0 1 1 1 0 BUD22 BNIP2 PF12496.8 EGO21969.1 - 1.1 9.7 6.1 2.8 8.4 6.1 1.7 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SDA1 PF05285.12 EGO21969.1 - 2.4 7.5 7.8 4.5 6.6 7.8 1.4 1 0 0 1 1 1 0 SDA1 GCIP PF13324.6 EGO21969.1 - 5.6 6.5 8.5 13 5.3 8.5 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting F-box-like PF12937.7 EGO21970.1 - 0.011 15.6 1.4 0.011 15.6 1.4 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EGO21970.1 - 0.018 14.9 3.3 0.028 14.3 0.5 2.6 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 EGO21970.1 - 0.38 11.2 3.8 11 6.7 0.0 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) RPN5_C PF18098.1 EGO21972.1 - 0.042 14.0 0.3 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain ROKNT PF08067.11 EGO21972.1 - 0.19 12.0 3.1 0.62 10.4 3.1 1.9 1 1 0 1 1 1 0 ROKNT (NUC014) domain Pkinase PF00069.25 EGO21977.1 - 2.6e-06 27.0 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGO21977.1 - 8.2e-06 24.8 0.0 1.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO21977.1 - 0.00072 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGO21977.1 - 0.0027 17.0 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO21977.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGO21977.1 - 0.035 13.7 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Imm43 PF15570.6 EGO21978.1 - 0.089 12.8 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Immunity protein 43 Plavaka PF18759.1 EGO21981.1 - 6.1e-35 121.0 0.2 8.4e-35 120.5 0.2 1.1 1 0 0 1 1 1 1 Plavaka transposase Sec63 PF02889.16 EGO21982.1 - 0.00011 21.4 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DUF356 PF04009.12 EGO21982.1 - 0.017 15.4 0.2 0.042 14.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF356) zf-CCHC PF00098.23 EGO21984.1 - 1.1e-06 28.4 3.8 2.1e-06 27.5 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO21984.1 - 3.4e-06 27.3 0.4 9.9e-06 25.8 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.6 EGO21984.1 - 0.0073 16.0 1.0 0.015 15.0 1.0 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger DUF4939 PF16297.5 EGO21984.1 - 0.063 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC_3 PF13917.6 EGO21984.1 - 2.1 8.4 6.6 0.87 9.6 3.7 1.9 2 0 0 2 2 2 0 Zinc knuckle Baculo_VP91_N PF08475.10 EGO21985.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Nop14 PF04147.12 EGO21986.1 - 0.013 13.7 12.7 0.021 13.1 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGO21986.1 - 0.018 14.4 12.7 0.03 13.7 12.7 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EGO21986.1 - 3.1 7.1 13.8 4.4 6.6 13.8 1.3 1 0 0 1 1 1 0 SDA1 Plavaka PF18759.1 EGO21987.1 - 2.4e-16 59.9 0.2 3.4e-16 59.4 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-met PF12874.7 EGO21987.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGO21987.1 - 0.59 11.1 0.1 0.59 11.1 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase_fungal PF17667.1 EGO21988.1 - 4.3e-21 75.2 0.2 5e-16 58.5 0.0 2.3 3 0 0 3 3 3 2 Fungal protein kinase DUF1422 PF07226.11 EGO21988.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) zf-CCHC PF00098.23 EGO21989.1 - 1.4e-06 28.1 4.7 2.6e-06 27.3 4.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO21989.1 - 2.9e-06 27.5 0.5 8.1e-06 26.0 0.3 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO21989.1 - 0.25 11.3 4.8 0.3 11.1 3.0 2.0 2 0 0 2 2 2 0 Zinc knuckle Sec2p PF06428.11 EGO21990.1 - 0.021 14.8 0.4 0.029 14.3 0.4 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF5339 PF17274.2 EGO21990.1 - 0.19 12.6 1.3 3.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Rap1_C PF11626.8 EGO21991.1 - 0.018 15.1 0.3 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Arb1 PF09692.10 EGO21993.1 - 2.7e-06 26.8 0.0 1.4e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Glyco_hydro_31 PF01055.26 EGO21994.1 - 1.5e-147 492.4 4.9 1.9e-147 492.0 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGO21994.1 - 1.9e-37 128.0 0.0 3.6e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGO21994.1 - 7.4e-14 51.8 0.7 3e-13 49.9 0.7 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like PP2C PF00481.21 EGO21995.1 - 5e-31 108.3 0.0 1.2e-30 107.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGO21995.1 - 1.2e-05 25.3 0.0 0.007 16.3 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGO21995.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Pkinase PF00069.25 EGO21998.1 - 2.1e-49 168.3 0.0 3.5e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO21998.1 - 1.7e-24 86.5 0.0 3.4e-24 85.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO21998.1 - 0.0034 16.2 0.1 0.0034 16.2 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGO21998.1 - 0.0062 15.6 0.1 0.0099 14.9 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGO21998.1 - 0.025 14.2 0.7 0.99 9.0 0.7 2.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EGO21998.1 - 0.035 13.5 1.8 0.042 13.2 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclase PF04199.13 EGO21999.1 - 9.9e-15 55.0 0.0 2.7e-14 53.6 0.0 1.6 1 1 1 2 2 2 1 Putative cyclase Shugoshin_C PF07557.11 EGO22000.1 - 1.7e-08 34.1 4.3 1.7e-08 34.1 4.3 2.4 2 0 0 2 2 2 1 Shugoshin C terminus Shugoshin_N PF07558.11 EGO22000.1 - 2.3e-07 30.6 3.0 4.8e-07 29.5 3.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 EGO22000.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor MFS_1 PF07690.16 EGO22006.1 - 1.3e-46 159.2 42.6 9.9e-45 153.0 42.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO22006.1 - 3.2e-09 35.8 11.0 5.4e-09 35.0 11.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO22006.1 - 2.4e-07 30.0 9.3 2.4e-07 30.0 9.3 3.5 1 1 1 3 3 3 2 Sugar (and other) transporter RHS PF03527.14 EGO22007.1 - 0.6 9.9 5.5 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 RHS protein Omega_Repress PF07764.11 EGO22013.1 - 0.046 14.3 0.1 0.087 13.4 0.1 1.5 1 0 0 1 1 1 0 Omega Transcriptional Repressor MFS_1 PF07690.16 EGO22014.1 - 7.1e-19 67.9 16.2 7.1e-19 67.9 16.2 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EGO22014.1 - 0.0082 14.5 1.2 0.014 13.7 1.2 1.5 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family C2 PF00168.30 EGO22016.1 - 5e-15 55.6 0.1 8.4e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.16 EGO22017.1 - 1.5e-40 139.2 28.6 1.5e-40 139.2 28.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO22017.1 - 4.3e-08 32.4 15.7 4.7e-08 32.3 13.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Phytase PF02333.15 EGO22022.1 - 0.037 13.0 0.0 0.041 12.9 0.0 1.0 1 0 0 1 1 1 0 Phytase MFS_1 PF07690.16 EGO22023.1 - 6.2e-36 124.0 25.6 7.6e-36 123.8 25.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO22023.1 - 1e-10 41.1 5.7 1e-10 41.1 5.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter AMP-binding PF00501.28 EGO22024.1 - 1.4e-32 112.8 0.0 2.1e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EGO22024.1 - 7.8e-19 68.7 0.0 1.2e-18 68.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EGO22024.1 - 5e-10 39.6 0.2 1.3e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGO22024.1 - 5.4e-09 36.9 0.1 2.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 EGO22024.1 - 0.0023 18.5 0.0 0.0037 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO22024.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EGO22024.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 EGO22024.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EGO22024.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.13 EGO22024.1 - 0.061 13.0 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EGO22024.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acyl_transf_1 PF00698.21 EGO22026.1 - 3.3e-07 30.1 0.0 3.8e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain LrgB PF04172.16 EGO22030.1 - 0.023 14.3 6.1 0.065 12.8 0.6 2.4 2 0 0 2 2 2 0 LrgB-like family E1-E2_ATPase PF00122.20 EGO22030.1 - 1.1 8.8 4.6 0.26 10.8 1.1 1.8 2 0 0 2 2 2 0 E1-E2 ATPase COX14 PF14880.6 EGO22030.1 - 1.3 8.9 4.7 1.2 9.0 0.1 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Synaptobrevin PF00957.21 EGO22030.1 - 6.8 6.6 6.2 2.9 7.8 0.5 2.4 2 0 0 2 2 2 0 Synaptobrevin RNase_PH_C PF03725.15 EGO22031.1 - 0.016 15.3 0.1 1.7 8.7 0.0 2.7 3 1 0 3 3 3 0 3' exoribonuclease family, domain 2 RRN3 PF05327.11 EGO22031.1 - 0.49 8.9 3.6 0.6 8.6 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ADH_N PF08240.12 EGO22032.1 - 8.4e-26 90.0 1.4 1.3e-25 89.4 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO22032.1 - 2.7e-22 79.1 0.1 5.3e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO22032.1 - 0.0017 19.4 0.0 0.0033 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO22032.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EGO22032.1 - 0.15 11.5 0.5 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DUF2890 PF11081.8 EGO22033.1 - 0.62 10.2 2.8 0.67 10.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Brix PF04427.18 EGO22034.1 - 4.5e-40 137.8 0.0 6e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain SCAB-PH PF17684.1 EGO22034.1 - 0.041 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein DUF3391 PF11871.8 EGO22036.1 - 0.12 13.0 3.0 0.32 11.5 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TFIIA PF03153.13 EGO22036.1 - 2.9 7.8 36.8 3.9 7.4 36.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4118 PF13493.6 EGO22041.1 - 0.062 13.1 0.4 0.15 11.9 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) HTH_30 PF13556.6 EGO22042.1 - 0.026 14.3 0.6 0.042 13.6 0.3 1.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Ibs_toxin PF13956.6 EGO22042.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Yae1_N PF09811.9 EGO22044.1 - 0.0018 17.9 1.1 0.0029 17.3 1.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal GGA_N-GAT PF18308.1 EGO22044.1 - 0.0056 16.3 0.4 0.015 14.9 0.4 1.7 1 0 0 1 1 1 1 GGA N-GAT domain AAA_13 PF13166.6 EGO22044.1 - 0.079 11.6 8.1 0.11 11.1 8.1 1.1 1 0 0 1 1 1 0 AAA domain PEARLI-4 PF05278.12 EGO22044.1 - 0.18 11.4 4.9 0.44 10.1 4.9 1.6 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4407 PF14362.6 EGO22044.1 - 1.3 8.3 19.4 2.2 7.6 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RWD PF05773.22 EGO22045.1 - 2.4e-08 34.2 0.1 4.8e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 RWD domain Sds3 PF08598.11 EGO22045.1 - 0.0033 17.5 0.7 0.0061 16.6 0.7 1.4 1 0 0 1 1 1 1 Sds3-like Pkinase PF00069.25 EGO22046.1 - 6.9e-06 25.6 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO22046.1 - 1.3e-05 25.3 0.2 2.4e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO22046.1 - 0.0036 16.7 0.1 0.0062 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO22046.1 - 0.033 13.8 0.3 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family NDK PF00334.19 EGO22047.1 - 8e-54 181.3 0.0 9e-54 181.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Plavaka PF18759.1 EGO22048.1 - 3.9e-23 82.2 0.0 8.5e-23 81.1 0.0 1.5 2 0 0 2 2 2 1 Plavaka transposase TcdA_TcdB_pore PF12920.7 EGO22050.1 - 0.048 11.9 1.2 0.055 11.7 1.2 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Ribosomal_L29 PF00831.23 EGO22050.1 - 0.13 12.2 1.8 0.21 11.6 1.8 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein B277 PF17623.2 EGO22050.1 - 0.52 9.3 4.0 0.43 9.6 1.9 1.7 1 1 1 2 2 2 0 Domain of unknown function Aconitase PF00330.20 EGO22052.1 - 2.9e-152 507.9 0.0 3.7e-152 507.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO22052.1 - 3.2e-34 118.1 0.0 5.7e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EGO22052.1 - 0.055 12.2 0.0 0.43 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF521) MutS_V PF00488.21 EGO22055.1 - 3.7e-71 239.1 0.8 4.8e-70 235.4 0.3 2.3 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EGO22055.1 - 5.4e-36 124.6 1.2 9.3e-36 123.8 1.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGO22055.1 - 6.4e-22 77.9 0.0 1.8e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGO22055.1 - 5e-12 46.3 0.0 1.3e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 EGO22055.1 - 0.00066 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGO22055.1 - 0.01 16.3 0.0 0.041 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGO22055.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO22055.1 - 0.082 13.4 0.1 0.7 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 EGO22055.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGO22056.1 - 3.9e-72 242.8 0.0 4.5e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22056.1 - 2.6e-40 138.3 0.0 3.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO22056.1 - 2.9e-05 23.2 0.0 3.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO22056.1 - 0.0016 17.9 0.0 0.0042 16.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGO22056.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO22056.1 - 0.021 14.8 0.0 0.071 13.0 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO22056.1 - 0.044 13.4 0.1 0.087 12.4 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGO22056.1 - 0.28 10.7 1.1 1.9 8.1 0.2 2.2 2 1 1 3 3 3 0 RIO1 family Tma16 PF11176.8 EGO22057.1 - 1.2e-43 148.5 0.8 1.5e-43 148.2 0.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Alb1 PF09135.11 EGO22057.1 - 5 8.1 11.4 16 6.5 4.3 2.5 3 0 0 3 3 3 0 Alb1 MOZART1 PF12554.8 EGO22058.1 - 2e-25 88.3 0.4 2.5e-25 88.0 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Acetyltransf_7 PF13508.7 EGO22059.1 - 9.6e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO22059.1 - 3.5e-09 36.9 0.0 2.6e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO22059.1 - 2.3e-08 33.9 0.0 3.9e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGO22059.1 - 7.7e-07 29.1 0.1 1.9e-05 24.6 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO22059.1 - 1.1e-06 29.4 0.0 1.5e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGO22059.1 - 0.005 16.3 0.0 0.0072 15.8 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGO22059.1 - 0.0069 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase P2_Phage_GpR PF06891.11 EGO22059.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) Acetyltransf_13 PF13880.6 EGO22059.1 - 0.021 14.8 0.4 0.058 13.4 0.1 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 EGO22059.1 - 0.12 12.5 0.0 0.36 10.9 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.19 EGO22060.1 - 4.5e-62 210.3 0.0 6.6e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGO22060.1 - 0.00027 20.2 0.3 0.00046 19.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO22060.1 - 0.00028 21.0 0.1 0.00073 19.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO22060.1 - 0.00072 18.4 0.1 0.0014 17.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 EGO22060.1 - 0.0046 15.9 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 EGO22060.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EGO22060.1 - 0.022 14.0 0.0 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO22060.1 - 0.03 13.6 0.3 0.052 12.8 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO22060.1 - 0.032 13.6 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGO22060.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 EGO22060.1 - 0.074 12.6 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EGO22060.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO22060.1 - 0.18 12.4 0.0 0.89 10.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DJ-1_PfpI PF01965.24 EGO22061.1 - 4.9e-15 55.7 0.0 5.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 EGO22062.1 - 1.2e-14 54.5 0.0 2.7e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGO22062.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I FAD_binding_3 PF01494.19 EGO22063.1 - 2.9e-67 227.4 0.0 5.3e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO22063.1 - 0.00017 21.7 0.0 0.00075 19.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO22063.1 - 0.00051 19.4 0.0 0.0029 16.9 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO22063.1 - 0.0007 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO22063.1 - 0.0013 18.4 0.0 0.0039 16.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO22063.1 - 0.0016 17.2 0.0 0.0036 16.1 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGO22063.1 - 0.0052 16.1 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO22063.1 - 0.0052 16.0 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EGO22063.1 - 0.008 16.2 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGO22063.1 - 0.017 14.5 0.1 0.039 13.3 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EGO22063.1 - 0.027 13.6 0.1 0.062 12.4 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 EGO22063.1 - 0.039 14.2 0.4 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain YtfJ_HI0045 PF09695.10 EGO22063.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) hDGE_amylase PF14701.6 EGO22066.1 - 2.5e-160 534.4 0.0 3.3e-160 534.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGO22066.1 - 3.7e-121 404.7 0.0 5.2e-121 404.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGO22066.1 - 4.5e-80 269.0 0.0 6.3e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EGO22066.1 - 2.4e-21 75.6 0.0 6.1e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF5094 PF17015.5 EGO22070.1 - 0.016 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) BCL_N PF04714.13 EGO22072.1 - 0.00033 20.7 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 BCL7, N-terminal conserver region SCA7 PF08313.12 EGO22073.1 - 1.7e-28 98.3 0.2 1.7e-28 98.3 0.2 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain FAD_binding_3 PF01494.19 EGO22075.1 - 8.3e-21 74.6 0.0 2.7e-20 72.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO22075.1 - 2.7e-10 40.4 0.8 8e-08 32.2 0.4 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO22075.1 - 3.8e-09 36.6 0.1 1.5e-08 34.7 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO22075.1 - 3e-07 29.9 0.0 5.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGO22075.1 - 5.6e-07 28.6 0.0 8e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EGO22075.1 - 2.2e-05 24.0 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EGO22075.1 - 3.5e-05 23.2 0.1 1.5e+02 1.4 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO22075.1 - 8.7e-05 21.7 0.2 0.0015 17.6 0.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EGO22075.1 - 0.00051 19.3 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EGO22075.1 - 0.00081 18.7 0.9 0.017 14.4 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO22075.1 - 0.001 19.6 0.1 0.0034 17.9 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO22075.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EGO22075.1 - 0.015 14.4 0.2 0.022 13.8 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO22075.1 - 0.028 13.3 0.1 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 EGO22075.1 - 0.059 12.7 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase ApbA PF02558.16 EGO22075.1 - 0.074 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EGO22075.1 - 0.11 12.5 0.3 1 9.3 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 EGO22077.1 - 5.5e-15 55.1 0.3 3.2e-14 52.6 0.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpc4 PF05132.14 EGO22078.1 - 7.2e-31 107.6 0.3 7.2e-31 107.6 0.3 2.5 2 1 0 2 2 2 1 RNA polymerase III RPC4 Pribosyltran PF00156.27 EGO22079.1 - 0.00029 20.4 0.0 0.00041 19.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.27 EGO22080.1 - 7.4e-66 218.1 2.4 1.7e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Alg14 PF08660.11 EGO22080.1 - 0.029 14.3 0.2 0.41 10.6 0.1 2.0 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like KduI PF04962.12 EGO22080.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 1 1 2 2 2 0 KduI/IolB family DUF4499 PF14934.6 EGO22080.1 - 0.068 13.5 0.2 0.15 12.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) p450 PF00067.22 EGO22082.1 - 9e-67 225.8 0.0 1e-66 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PXA PF02194.15 EGO22085.1 - 0.073 13.0 0.2 0.34 10.9 0.0 1.9 1 1 1 2 2 2 0 PXA domain Caveolin PF01146.17 EGO22087.1 - 0.12 12.3 2.8 0.28 11.1 2.8 1.6 1 0 0 1 1 1 0 Caveolin Helicase_C PF00271.31 EGO22094.1 - 1.6e-12 47.8 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGO22094.1 - 0.0013 19.4 0.2 0.0077 16.9 0.1 2.2 2 0 0 2 2 2 1 RecQ zinc-binding zf-CCHC PF00098.23 EGO22098.1 - 8.4e-08 32.0 1.2 1.2e-07 31.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO22098.1 - 0.0087 15.6 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCHC_6 PF15288.6 EGO22098.1 - 0.13 12.1 1.5 0.22 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Ank_2 PF12796.7 EGO22099.1 - 7.3e-44 148.3 1.2 8.1e-14 52.0 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO22099.1 - 3.4e-38 129.5 4.3 2.9e-09 37.3 0.0 8.3 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EGO22099.1 - 1.3e-29 101.3 13.6 0.00098 19.5 0.3 9.7 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 EGO22099.1 - 3.6e-28 94.5 1.8 0.00018 21.7 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EGO22099.1 - 1.3e-26 92.3 5.6 1.1e-07 32.0 0.0 6.5 4 2 1 6 6 6 4 Ankyrin repeats (many copies) p450 PF00067.22 EGO22102.1 - 2.6e-10 39.7 0.0 3.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO22103.1 - 3.3e-60 204.1 0.0 8.9e-60 202.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TRAUB PF08164.12 EGO22105.1 - 1.7e-30 105.3 0.2 5.6e-30 103.7 0.2 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EGO22105.1 - 1.3e-25 90.7 0.4 1.3e-25 90.7 0.4 2.7 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor RNAse_A_bac PF18431.1 EGO22105.1 - 0.042 14.8 2.9 2.1 9.4 0.3 3.4 2 1 1 3 3 3 0 Bacterial CdiA-CT RNAse A domain YL1 PF05764.13 EGO22105.1 - 0.84 9.7 18.0 0.15 12.2 9.0 2.3 2 0 0 2 2 2 0 YL1 nuclear protein PX PF00787.24 EGO22106.1 - 8.2e-22 77.3 0.4 3.4e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGO22106.1 - 2.7e-05 23.8 6.6 0.012 15.2 1.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EGO22106.1 - 0.0067 16.1 0.3 0.0067 16.1 0.3 1.9 2 0 0 2 2 2 1 BAR domain DUF4391 PF14335.6 EGO22106.1 - 0.066 12.9 0.6 0.16 11.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) EamA PF00892.20 EGO22107.1 - 5e-07 30.0 7.6 5e-07 30.0 7.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family CPSase_L_D2 PF02786.17 EGO22108.1 - 2.4e-81 272.3 0.1 4.5e-81 271.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGO22108.1 - 4e-68 229.1 0.0 7.6e-68 228.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGO22108.1 - 3.7e-40 136.9 0.1 7.6e-40 135.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGO22108.1 - 2.1e-29 101.8 0.0 7.5e-29 100.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGO22108.1 - 4.2e-29 101.9 0.0 1.1e-28 100.6 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGO22108.1 - 8.1e-18 64.0 3.4 8.1e-18 64.0 3.4 2.5 3 0 0 3 3 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGO22108.1 - 5.3e-12 45.4 3.6 1.1e-06 28.4 0.1 2.8 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EGO22108.1 - 1.1e-10 41.3 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGO22108.1 - 9.9e-09 35.0 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EGO22108.1 - 5.9e-06 25.6 0.7 0.0017 17.6 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EGO22108.1 - 8.1e-06 26.0 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGO22108.1 - 1.7e-05 25.5 0.8 0.32 11.7 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 EGO22108.1 - 7.7e-05 22.3 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 EGO22108.1 - 0.0014 18.5 2.9 0.0035 17.2 0.6 2.7 2 1 1 3 3 3 1 Glycine cleavage H-protein RnfC_N PF13375.6 EGO22108.1 - 0.004 17.1 0.8 0.052 13.5 0.6 2.6 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 EGO22108.1 - 0.0045 16.5 0.8 0.0094 15.4 0.2 1.7 2 0 0 2 2 2 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 EGO22108.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EGO22108.1 - 0.0064 16.1 0.0 0.022 14.3 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 EGO22108.1 - 0.0081 15.4 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 EGO22108.1 - 0.023 14.7 0.3 0.35 10.8 0.3 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) PNPase PF03726.14 EGO22108.1 - 0.099 13.2 0.1 0.28 11.7 0.1 1.8 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PTS_EIIA_1 PF00358.20 EGO22108.1 - 0.12 12.2 0.1 0.68 9.7 0.1 2.3 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NMO PF03060.15 EGO22109.1 - 4.1e-41 141.5 0.8 1.6e-39 136.3 0.8 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO22109.1 - 2.1e-05 23.7 0.0 0.087 11.8 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO22109.1 - 0.0004 19.5 1.2 0.00058 19.0 0.3 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase LSM PF01423.22 EGO22110.1 - 6.6e-17 61.0 0.0 1.1e-16 60.3 0.0 1.3 1 1 0 1 1 1 1 LSM domain RhoGAP PF00620.27 EGO22115.1 - 9.3e-38 129.4 0.0 1.6e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGO22115.1 - 2.5e-16 60.1 0.0 5.9e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 EGO22115.1 - 1.9e-06 27.8 0.0 3.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 EGO22115.1 - 0.0017 18.6 0.1 0.014 15.6 0.0 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain Spexin PF15171.6 EGO22116.1 - 0.062 13.5 0.0 0.064 13.5 0.0 1.1 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin SDH_alpha PF03313.15 EGO22117.1 - 2.1e-100 335.7 0.6 2.6e-100 335.4 0.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EGO22117.1 - 6.9e-12 46.0 0.0 1.4e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Cyclin_N PF00134.23 EGO22118.1 - 2.6e-10 40.1 0.0 4.7e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain AAA_33 PF13671.6 EGO22119.1 - 2.1e-15 57.1 0.0 3.3e-09 37.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO22119.1 - 9.1e-05 23.0 0.0 0.0051 17.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGO22119.1 - 0.00012 21.6 0.0 0.2 11.1 0.0 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 tRNA_lig_kinase PF08303.11 EGO22119.1 - 0.0049 17.0 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain dNK PF01712.19 EGO22119.1 - 0.023 14.5 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase 6PF2K PF01591.18 EGO22119.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.12 EGO22119.1 - 0.074 12.9 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 EGO22119.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase TPR_2 PF07719.17 EGO22120.1 - 2.4e-14 52.2 1.5 1.9e-06 27.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO22120.1 - 7.5e-14 50.9 0.6 2.3e-06 27.2 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO22120.1 - 1.1e-13 50.6 7.4 3.9e-07 29.6 0.3 4.5 3 2 2 5 5 5 4 TPR repeat TPR_16 PF13432.6 EGO22120.1 - 1.2e-11 45.0 1.1 5.6e-05 23.7 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO22120.1 - 2.8e-11 43.0 1.0 0.016 15.5 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO22120.1 - 2.1e-10 40.8 2.0 0.0017 18.6 0.2 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO22120.1 - 2.5e-10 40.7 0.6 0.00073 20.0 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO22120.1 - 2.3e-08 33.6 3.2 0.029 14.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO22120.1 - 6.3e-08 32.8 4.1 0.003 18.3 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO22120.1 - 3.3e-06 26.8 2.8 0.042 13.7 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22120.1 - 4.9e-05 23.1 4.3 0.23 11.6 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO22120.1 - 8.6e-05 22.7 0.1 0.05 13.8 0.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGO22120.1 - 0.00015 22.2 1.0 0.39 11.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 EGO22120.1 - 0.0012 18.9 2.2 2.5 8.2 0.2 3.3 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 EGO22120.1 - 0.0047 17.2 2.6 0.18 12.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EGO22120.1 - 0.0058 16.7 1.3 0.0068 16.5 0.2 1.8 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 EGO22120.1 - 0.016 15.3 1.2 6.4 6.9 0.1 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 EGO22120.1 - 0.016 15.7 1.7 1.3 9.9 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO22120.1 - 0.07 13.3 0.0 14 5.9 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EGO22120.1 - 0.17 12.0 2.4 5.1 7.2 0.1 3.0 3 0 0 3 3 3 0 Exonuclease VII small subunit Tim17 PF02466.19 EGO22121.1 - 3.3e-25 88.6 7.4 4.7e-25 88.1 7.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Velvet PF11754.8 EGO22122.1 - 1.4e-32 113.6 3.2 2.3e-20 73.6 0.0 3.1 2 1 1 3 3 3 2 Velvet factor DUF2076 PF09849.9 EGO22123.1 - 4.3 7.3 19.3 6.9 6.6 19.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cytochrom_C1 PF02167.15 EGO22124.1 - 3.3e-97 324.5 0.0 4e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EGO22124.1 - 0.00032 21.0 0.0 0.00067 19.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGO22124.1 - 0.011 16.9 0.2 0.035 15.2 0.1 1.9 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.16 EGO22125.1 - 1.4e-23 83.8 5.7 2.4e-21 76.4 5.7 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGO22125.1 - 3.9e-09 36.6 0.9 7e-09 35.8 0.2 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family COX5A PF02284.16 EGO22125.1 - 0.043 13.8 0.1 0.16 12.0 0.1 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va tRNA_int_endo PF01974.17 EGO22127.1 - 3.9e-19 68.5 0.2 1.2e-18 66.9 0.2 1.8 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGO22127.1 - 2.5e-05 23.8 0.0 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain SDH_alpha PF03313.15 EGO22127.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain WD40 PF00400.32 EGO22128.1 - 1.1e-10 41.9 9.7 0.13 13.2 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat HAND PF09110.11 EGO22128.1 - 0.19 12.5 9.7 0.41 11.4 9.7 1.4 1 0 0 1 1 1 0 HAND Aminotran_5 PF00266.19 EGO22129.1 - 1.8e-32 112.7 0.0 2.4e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 EGO22129.1 - 0.036 14.1 1.3 0.2 11.7 0.1 2.4 2 1 1 3 3 3 0 B12 binding domain KR PF08659.10 EGO22129.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 KR domain NIR_SIR PF01077.22 EGO22130.1 - 1.4e-49 167.7 0.0 5.6e-46 155.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EGO22130.1 - 2.4e-31 107.4 0.0 1e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EGO22130.1 - 1e-28 100.4 0.0 1.9e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EGO22130.1 - 0.069 12.9 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.7 EGO22130.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain SQHop_cyclase_N PF13249.6 EGO22131.1 - 1.3e-56 191.9 0.1 9.9e-47 159.4 0.1 3.5 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGO22131.1 - 2.8e-50 171.2 1.2 1.2e-46 159.3 0.3 2.9 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EGO22131.1 - 1.6e-37 126.9 2.3 7.8e-10 38.3 0.3 6.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EGO22131.1 - 0.00013 21.1 0.1 0.04 12.9 0.0 3.7 1 1 2 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EGO22131.1 - 0.00015 21.2 0.2 3.4 6.9 0.0 4.6 2 2 1 5 5 5 2 Pectic acid lyase DUF3958 PF13125.6 EGO22134.1 - 5.8 7.2 19.1 2.8 8.2 11.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Actin PF00022.19 EGO22135.1 - 5.3e-41 140.6 0.0 2.7e-40 138.3 0.0 1.8 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.26 EGO22136.1 - 1.9e-21 75.6 0.0 2.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family bVLRF1 PF18826.1 EGO22137.1 - 3.1e-68 228.4 0.0 7.2e-68 227.1 0.0 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor MFMR_assoc PF16596.5 EGO22137.1 - 0.0036 17.7 1.3 0.0092 16.4 0.4 2.1 2 0 0 2 2 2 1 Disordered region downstream of MFMR Ank_2 PF12796.7 EGO22137.1 - 0.13 12.9 0.0 1 10.0 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF1682 PF07946.14 EGO22137.1 - 8.4 5.5 7.5 18 4.4 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PMM PF03332.13 EGO22138.1 - 2.4e-105 351.2 0.4 2.8e-105 351.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGO22138.1 - 0.0027 17.5 0.0 0.072 12.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGO22138.1 - 0.014 15.0 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 EGO22138.1 - 0.029 14.8 0.0 9.4 6.6 0.0 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HCBP_related PF06594.11 EGO22138.1 - 0.13 12.2 0.3 0.38 10.7 0.3 1.8 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain DNA_pol_B PF00136.21 EGO22139.1 - 1.6e-146 488.7 0.3 2.1e-146 488.3 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGO22139.1 - 1.2e-84 284.4 0.0 3.7e-84 282.7 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGO22139.1 - 5.2e-18 65.3 7.3 1.2e-17 64.1 7.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EGO22139.1 - 0.00043 19.3 0.3 0.0026 16.7 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EGO22139.1 - 0.015 15.3 0.1 0.058 13.4 0.1 1.9 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EGO22139.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Cnd2 PF05786.14 EGO22140.1 - 5.1e-180 600.8 12.8 9e-180 600.0 12.8 1.3 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGO22140.1 - 0.85 9.9 0.0 0.85 9.9 0.0 2.4 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal 5_nucleotid_C PF02872.18 EGO22141.1 - 0.058 13.6 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Med11 PF10280.9 EGO22143.1 - 0.088 13.3 0.1 0.29 11.6 0.1 1.8 1 1 0 1 1 1 0 Mediator complex protein Sirohm_synth_C PF14823.6 EGO22144.1 - 0.026 14.1 0.8 0.055 13.1 0.1 1.9 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DEAD PF00270.29 EGO22144.1 - 0.12 12.1 0.1 0.81 9.4 0.0 2.3 2 1 1 3 3 3 0 DEAD/DEAH box helicase Glyco_hyd_65N_2 PF14498.6 EGO22145.1 - 0.022 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Urocanase PF01175.18 EGO22145.1 - 0.026 14.1 0.4 0.038 13.6 0.4 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF3375 PF11855.8 EGO22146.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Atx10homo_assoc PF09759.9 EGO22150.1 - 3.4e-25 87.9 0.2 3e-24 84.9 0.1 2.4 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EGO22150.1 - 0.15 12.4 0.0 0.64 10.4 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats BRAP2 PF07576.12 EGO22151.1 - 7.4e-29 99.9 0.0 1.5e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EGO22151.1 - 1.1e-19 70.5 4.4 2.5e-19 69.4 4.4 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGO22151.1 - 2.3e-08 34.2 9.5 2.3e-08 34.2 9.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO22151.1 - 2.5e-06 27.2 9.4 6.1e-06 26.0 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO22151.1 - 1.5e-05 24.8 7.7 3.4e-05 23.6 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO22151.1 - 1.8e-05 25.0 5.7 4.7e-05 23.6 5.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGO22151.1 - 1.9e-05 24.3 4.9 5e-05 22.9 4.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGO22151.1 - 4.1e-05 23.5 3.3 4.1e-05 23.5 3.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO22151.1 - 0.00098 18.9 6.8 0.00098 18.9 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO22151.1 - 0.0038 17.2 6.7 0.0038 17.2 6.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGO22151.1 - 0.0081 16.2 3.5 0.018 15.1 3.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO22151.1 - 0.044 13.6 6.2 0.12 12.2 6.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.6 EGO22151.1 - 0.45 9.8 12.4 0.75 9.1 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2362 PF10154.9 EGO22151.1 - 0.5 9.2 10.5 0.71 8.8 10.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Laminin_II PF06009.12 EGO22151.1 - 1.7 8.7 10.6 0.21 11.6 4.2 2.1 2 0 0 2 2 2 0 Laminin Domain II Rootletin PF15035.6 EGO22151.1 - 1.7 8.6 19.6 10 6.1 19.6 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 EGO22151.1 - 2.3 8.3 8.6 2.7 8.1 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S49 PF01343.18 EGO22151.1 - 2.6 8.0 6.4 4.5 7.2 6.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 Prok-RING_4 PF14447.6 EGO22151.1 - 3.8 7.5 21.0 1.5 8.8 11.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Fib_alpha PF08702.10 EGO22151.1 - 6 7.0 11.2 3.1 8.0 2.7 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nuc_recep-AF1 PF11825.8 EGO22153.1 - 0.015 15.4 0.3 0.017 15.2 0.3 1.1 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Barttin PF15462.6 EGO22154.1 - 0.052 13.3 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) ParA PF10609.9 EGO22155.1 - 5.8e-96 320.7 0.0 6.8e-96 320.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGO22155.1 - 5.5e-09 36.2 0.0 1.6e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EGO22155.1 - 2.1e-05 23.9 1.4 0.0023 17.2 0.1 2.8 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EGO22155.1 - 0.00067 19.6 0.1 0.0061 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EGO22155.1 - 0.0017 17.9 0.0 0.0042 16.6 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EGO22155.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO22155.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 EGO22155.1 - 0.029 13.8 0.0 1.2 8.6 0.0 2.4 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EGO22155.1 - 0.039 13.8 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGO22155.1 - 0.084 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 EGO22155.1 - 0.19 11.4 0.1 0.31 10.7 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Pkinase PF00069.25 EGO22156.1 - 2.2e-09 37.1 0.0 2.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22156.1 - 4.7e-05 22.8 0.0 6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Symplekin_C PF12295.8 EGO22157.1 - 3.3e-63 213.2 0.7 8.5e-63 211.8 0.7 1.8 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EGO22157.1 - 7.6e-49 166.4 0.1 1.9e-48 165.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Fungal_trans PF04082.18 EGO22158.1 - 2.7e-18 66.0 1.2 4.5e-18 65.2 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO22158.1 - 1.4e-09 38.0 11.1 2.3e-09 37.2 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 EGO22159.1 - 1.3e-25 89.8 12.7 1.6e-25 89.5 12.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EGO22159.1 - 0.0084 16.4 0.4 0.012 15.9 0.0 1.5 2 0 0 2 2 2 1 EF-hand domain DUF3824 PF12868.7 EGO22159.1 - 0.15 12.7 1.6 0.21 12.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S19 PF00203.21 EGO22160.1 - 8.4e-32 108.9 0.2 1.3e-31 108.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 EGO22160.1 - 0.17 11.9 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH RhoGAP PF00620.27 EGO22161.1 - 2.2e-34 118.5 0.0 4.2e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EGO22161.1 - 1.7e-26 92.2 33.9 1.1e-10 41.5 6.9 4.7 5 0 0 5 5 5 4 LIM domain SLC35F PF06027.12 EGO22163.1 - 3.1e-97 325.7 18.9 3.7e-97 325.5 18.9 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EGO22163.1 - 2.6e-09 36.5 0.8 2.6e-09 36.5 0.8 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF5518 PF17647.1 EGO22163.1 - 0.0071 16.5 5.6 0.0071 16.5 5.6 2.8 3 1 1 4 4 4 1 Family of unknown function (DUF5518) EamA PF00892.20 EGO22163.1 - 2.7 8.1 29.4 0.61 10.3 0.5 3.1 2 1 1 3 3 3 0 EamA-like transporter family Deltameth_res PF16020.5 EGO22163.1 - 3 7.8 5.1 2.5 8.1 0.1 3.2 4 0 0 4 4 4 0 Deltamethrin resistance MTCP1 PF08991.10 EGO22164.1 - 4.5e-06 26.8 1.3 6.7e-06 26.2 1.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EGO22164.1 - 7.9e-06 25.9 5.7 1.1e-05 25.4 5.7 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EGO22164.1 - 0.002 18.4 3.8 0.0038 17.5 3.8 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 EGO22164.1 - 0.024 14.9 2.8 0.16 12.2 2.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EGO22164.1 - 0.16 12.3 2.8 0.47 10.9 2.6 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) RRM_1 PF00076.22 EGO22165.1 - 2.4e-31 107.4 1.9 3.5e-15 55.6 0.1 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO22165.1 - 7.6e-07 29.2 0.0 0.00075 19.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EGO22165.1 - 0.0014 18.4 0.0 0.23 11.3 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_9 PF18444.1 EGO22165.1 - 0.025 14.4 0.0 5 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Fis1_TPR_C PF14853.6 EGO22166.1 - 1.5e-22 79.4 0.1 2.4e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGO22166.1 - 3.8e-16 58.4 0.0 6.1e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGO22166.1 - 0.00028 20.8 0.1 0.0006 19.7 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO22166.1 - 0.0086 15.9 0.3 0.015 15.1 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO22166.1 - 0.021 15.3 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO22166.1 - 0.026 15.1 0.0 0.077 13.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO22166.1 - 0.1 12.8 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M50B PF13398.6 EGO22167.1 - 6.6e-43 146.7 18.2 7.8e-43 146.4 18.2 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Histone_H2A_C PF16211.5 EGO22168.1 - 1.8e-17 62.7 0.5 3.9e-17 61.7 0.5 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGO22168.1 - 3e-17 63.2 0.0 4.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO22168.1 - 1.5e-06 28.4 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FCH PF00611.23 EGO22169.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.27 EGO22169.1 - 8.8e-08 32.1 0.0 2.8e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 EGO22169.1 - 3.5e-06 27.0 0.0 6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Vpu PF00558.19 EGO22169.1 - 0.45 10.3 1.7 1.3 8.8 1.7 1.7 1 0 0 1 1 1 0 Vpu protein Ribonucleas_3_3 PF14622.6 EGO22170.1 - 9.8e-08 32.2 0.0 3.4e-07 30.5 0.0 1.9 1 1 1 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 EGO22170.1 - 1.7e-07 31.8 0.0 3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EGO22170.1 - 0.00011 22.7 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Peptidase_M20 PF01546.28 EGO22171.1 - 5.5e-32 111.1 0.0 9.9e-32 110.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO22171.1 - 4.8e-13 49.0 0.0 9.5e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO22171.1 - 2.2e-05 24.3 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PPR_1 PF12854.7 EGO22172.1 - 0.15 11.8 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 PPR repeat MLTR_LBD PF17765.1 EGO22173.1 - 0.0031 17.7 0.7 0.0069 16.5 0.7 1.8 1 1 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain ABATE PF07336.11 EGO22173.1 - 0.035 14.8 1.1 0.067 13.9 0.6 1.6 1 1 1 2 2 2 0 Putative stress-induced transcription regulator HisKA PF00512.25 EGO22173.1 - 0.12 12.4 0.7 0.99 9.5 0.1 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF4226 PF10774.9 EGO22174.1 - 0.002 18.4 0.1 0.0035 17.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4226) Snf7 PF03357.21 EGO22174.1 - 0.02 14.5 0.3 0.026 14.1 0.3 1.3 1 0 0 1 1 1 0 Snf7 Turandot PF07240.11 EGO22174.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot DUF4653 PF15546.6 EGO22174.1 - 0.069 12.8 0.3 0.068 12.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Peptidase_M20 PF01546.28 EGO22175.1 - 3.5e-24 85.7 0.0 2.1e-23 83.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO22175.1 - 1.5e-13 50.6 0.0 2.6e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-C2H2 PF00096.26 EGO22177.1 - 9.2e-27 92.0 37.5 3.8e-06 27.1 0.0 8.0 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO22177.1 - 8.2e-26 89.2 40.7 8.8e-07 29.1 0.3 7.8 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO22177.1 - 1.3e-20 72.3 38.5 0.00019 22.0 1.2 7.9 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO22177.1 - 7.5e-08 32.2 27.6 0.24 11.5 1.5 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGO22177.1 - 9.7e-06 25.8 20.1 0.11 12.8 4.4 5.1 2 1 2 5 5 5 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 EGO22177.1 - 1.4e-05 25.6 29.5 0.51 11.0 1.5 7.4 3 1 4 7 7 7 3 FOXP coiled-coil domain zf_ZIC PF18366.1 EGO22177.1 - 2.5e-05 24.3 13.8 0.03 14.4 0.9 5.5 6 1 0 6 6 5 2 Zic proteins zinc finger domain zf-C2HC_2 PF13913.6 EGO22177.1 - 9.1e-05 22.3 4.5 1.9 8.5 0.2 5.1 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EGO22177.1 - 0.00012 21.8 22.5 0.044 13.6 0.2 6.8 7 0 0 7 7 6 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGO22177.1 - 0.00018 21.7 13.0 0.021 15.1 0.4 5.2 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EGO22177.1 - 0.00023 20.8 23.9 0.01 15.5 3.8 6.5 6 1 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 EGO22177.1 - 0.0006 20.1 17.7 0.28 11.5 6.8 4.8 3 2 2 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EGO22177.1 - 0.0037 17.7 15.8 0.058 13.8 1.2 3.4 3 1 0 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 EGO22177.1 - 0.035 14.0 0.8 0.23 11.4 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 EGO22177.1 - 0.3 11.4 22.6 0.33 11.3 0.9 4.9 4 2 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1 PF03811.13 EGO22177.1 - 0.49 10.2 8.5 0.43 10.3 1.0 3.0 2 0 0 2 2 2 0 InsA N-terminal domain zf-met PF12874.7 EGO22177.1 - 1 9.8 14.2 0.4 11.1 0.8 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 EGO22177.1 - 1.2 9.0 11.5 11 6.0 0.1 4.7 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) DUF629 PF04780.12 EGO22177.1 - 2.3 6.6 14.7 8.1 4.9 1.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF629) CCAP PF11105.8 EGO22177.1 - 6 6.8 5.3 3.4 7.6 1.1 2.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a CTP_transf_like PF01467.26 EGO22178.1 - 9.6e-15 55.0 0.0 1.6e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Lactamase_B PF00753.27 EGO22179.1 - 5.9e-10 39.5 0.0 1.3e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO22179.1 - 0.086 12.3 0.8 0.2 11.2 0.4 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO22180.1 - 1.7e-10 41.3 0.0 2.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO22180.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO22181.1 - 1.3e-09 38.4 0.1 1.9e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO22181.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain RHS PF03527.14 EGO22182.1 - 0.0081 15.9 0.1 0.28 11.0 0.0 2.2 2 0 0 2 2 2 2 RHS protein zf-CCCH_4 PF18044.1 EGO22183.1 - 2.9e-09 36.5 37.9 2.8e-05 23.8 6.6 3.9 3 0 0 3 3 3 3 CCCH-type zinc finger zf-C3HC4 PF00097.25 EGO22183.1 - 4.3e-08 32.9 5.2 4.3e-08 32.9 5.2 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO22183.1 - 8.2e-08 32.5 6.4 8.2e-08 32.5 6.4 3.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO22183.1 - 3.9e-07 29.8 6.0 3.9e-07 29.8 6.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO22183.1 - 8.4e-07 28.8 5.2 8.4e-07 28.8 5.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO22183.1 - 2.3e-06 27.5 4.6 3.4e-06 27.0 3.2 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EGO22183.1 - 1.2e-05 25.1 9.9 1.2e-05 25.1 9.9 4.7 4 0 0 4 4 4 2 Zinc finger domain zf-C3HC4_2 PF13923.6 EGO22183.1 - 3.8e-05 23.5 2.5 3.8e-05 23.5 2.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 EGO22183.1 - 0.0016 19.1 19.0 0.026 15.2 1.9 3.4 2 1 1 3 3 3 2 Torus domain zf-rbx1 PF12678.7 EGO22183.1 - 0.0017 18.6 6.4 0.0017 18.6 6.4 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO22183.1 - 0.011 15.5 6.2 0.011 15.5 6.2 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CCCH PF00642.24 EGO22183.1 - 0.018 15.0 5.0 0.018 15.0 5.0 4.4 4 0 0 4 4 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGO22183.1 - 5.7 7.2 18.3 0.085 13.1 2.2 3.5 2 2 1 3 3 3 0 Zinc-finger containing family SAGA-Tad1 PF12767.7 EGO22184.1 - 1.4e-24 87.1 0.0 3.4e-24 85.9 0.0 1.6 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EGO22184.1 - 0.029 14.1 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Pap_E4 PF02711.14 EGO22184.1 - 1.9 9.5 6.7 0.22 12.5 1.7 2.0 2 1 0 2 2 2 0 E4 protein GFO_IDH_MocA PF01408.22 EGO22185.1 - 4.5e-18 66.2 0.0 7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OHCU_decarbox PF09349.10 EGO22186.1 - 1.2e-31 110.3 0.0 1.4e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.31 EGO22187.1 - 4.8e-21 74.6 0.5 1.2e-20 73.4 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4948 PF16306.5 EGO22187.1 - 0.14 12.0 0.4 0.25 11.1 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4948) VAPB_antitox PF02697.14 EGO22187.1 - 0.52 11.1 6.5 1 10.1 0.7 3.2 2 1 2 4 4 4 0 Putative antitoxin Abhydrolase_1 PF00561.20 EGO22188.1 - 5.5e-19 68.8 0.0 2.6e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO22188.1 - 7.6e-11 43.0 0.0 9.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO22188.1 - 4.5e-10 39.2 0.0 9.6e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGO22188.1 - 0.00054 19.6 0.0 0.0042 16.7 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 EGO22188.1 - 0.0022 16.7 0.0 0.0048 15.6 0.0 1.5 2 0 0 2 2 2 1 Ndr family Thioesterase PF00975.20 EGO22188.1 - 0.078 13.1 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain Torsin PF06309.11 EGO22188.1 - 0.15 12.2 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Torsin Pkinase PF00069.25 EGO22189.1 - 1.3e-72 244.3 0.0 1.6e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22189.1 - 1.1e-31 110.0 0.0 2.4e-31 109.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO22189.1 - 0.003 16.5 0.2 0.32 9.9 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 EGO22189.1 - 0.024 13.9 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EGO22189.1 - 0.029 14.3 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGO22189.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NADH-u_ox-rdase PF10785.9 EGO22191.1 - 1e-33 115.9 0.5 1.5e-33 115.3 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EGO22191.1 - 2e-14 53.3 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit WD40 PF00400.32 EGO22192.1 - 2.3e-11 44.0 10.1 0.042 14.7 0.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO22192.1 - 1.2e-08 35.2 0.2 0.032 14.5 0.0 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EGO22192.1 - 0.025 14.3 0.3 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF1192 PF06698.11 EGO22192.1 - 0.11 12.5 1.4 0.31 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DnaJ PF00226.31 EGO22193.1 - 5.3e-20 71.3 0.1 8.4e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SH3_1 PF00018.28 EGO22194.1 - 7.1e-17 60.7 1.9 4.5e-07 29.4 0.1 3.1 2 1 0 2 2 2 2 SH3 domain SAM_1 PF00536.30 EGO22194.1 - 1.1e-11 45.0 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGO22194.1 - 2.2e-11 43.7 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EGO22194.1 - 6.6e-11 41.9 2.0 0.00012 21.8 0.2 2.7 2 1 0 2 2 2 2 Variant SH3 domain RA PF00788.23 EGO22194.1 - 5.8e-07 30.0 0.8 9.6e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.17 EGO22194.1 - 1.1e-06 28.3 0.3 0.00084 19.0 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 EGO22194.1 - 0.0017 18.6 5.1 0.14 12.4 0.6 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain SlyX PF04102.12 EGO22194.1 - 0.019 15.5 0.6 0.044 14.4 0.6 1.6 1 0 0 1 1 1 0 SlyX SH3_16 PF18348.1 EGO22194.1 - 0.16 11.8 2.4 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain NUDIX PF00293.28 EGO22195.1 - 4.9e-10 39.6 0.0 6.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 EGO22196.1 - 1.5e-46 159.2 27.4 1e-44 153.2 27.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO22196.1 - 4.7e-18 65.2 39.8 9e-10 38.0 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO22196.1 - 0.0099 14.3 0.4 0.0099 14.3 0.4 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DMT_YdcZ PF04657.13 EGO22196.1 - 0.029 14.7 2.1 0.029 14.7 2.1 4.1 3 2 1 4 4 4 0 Putative inner membrane exporter, YdcZ FG-GAP_2 PF14312.6 EGO22196.1 - 0.1 12.9 0.4 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 FG-GAP repeat SIP PF04954.13 EGO22199.1 - 0.022 15.3 0.1 0.025 15.1 0.1 1.1 1 0 0 1 1 1 0 Siderophore-interacting protein DEAD PF00270.29 EGO22202.1 - 5e-11 42.7 0.0 7.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO22202.1 - 4.3e-05 23.8 0.0 0.00016 22.0 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T4SS-DNA_transf PF02534.14 EGO22202.1 - 0.00041 19.3 0.1 0.0007 18.5 0.1 1.3 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 EGO22202.1 - 0.0028 17.7 0.1 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2956 PF11169.8 EGO22202.1 - 0.022 14.9 0.1 0.055 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TMEM135_C_rich PF15982.5 EGO22204.1 - 0.16 12.6 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 Myb_DNA-bind_3 PF12776.7 EGO22205.1 - 1.4e-06 29.2 1.9 1.4e-06 29.2 1.9 1.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO22205.1 - 0.0048 17.3 0.8 0.089 13.2 0.8 2.3 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 EGO22206.1 - 2.3e-06 27.8 2.7 6.7e-06 26.3 2.7 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_1 PF03184.19 EGO22207.1 - 6.9e-10 38.8 0.0 2.2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Jnk-SapK_ap_N PF09744.9 EGO22207.1 - 1 9.5 11.7 0.29 11.3 6.9 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PV-1 PF06637.11 EGO22208.1 - 0.087 11.6 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Transposase_21 PF02992.14 EGO22210.1 - 0.00095 18.5 0.0 0.00095 18.5 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 NAD_binding_5 PF07994.12 EGO22212.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase PQ-loop PF04193.14 EGO22214.1 - 3.1e-17 62.1 3.0 3.3e-11 42.8 1.1 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EGO22214.1 - 9.7e-05 23.2 3.6 0.00011 23.0 3.3 1.3 1 1 0 1 1 1 1 ER lumen protein retaining receptor DAD PF02109.16 EGO22214.1 - 0.064 13.6 0.7 0.13 12.6 0.7 1.5 1 0 0 1 1 1 0 DAD family TNFR_16_TM PF18422.1 EGO22214.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.8 4 0 0 4 4 4 0 Tumor necrosis factor receptor member 16 trans-membrane domain Clathrin PF00637.20 EGO22215.1 - 1.5e-201 660.3 27.1 1.5e-32 112.5 0.3 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EGO22215.1 - 3.9e-38 127.9 0.6 7.7e-06 26.0 0.1 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EGO22215.1 - 4.3e-30 103.4 0.5 1.6e-29 101.6 0.2 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 EGO22215.1 - 2e-11 43.0 2.8 4.3e-11 42.0 0.1 2.8 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 EGO22215.1 - 0.00037 20.8 5.0 3.6 7.9 0.1 6.2 5 2 1 6 6 6 1 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.14 EGO22215.1 - 0.00045 19.4 6.7 0.14 11.2 0.1 4.3 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 EGO22215.1 - 0.01 15.7 2.9 13 5.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22215.1 - 0.032 14.3 3.9 62 4.0 0.2 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Nucleoporin_N PF08801.11 EGO22215.1 - 0.095 11.4 0.0 0.22 10.2 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like PPR PF01535.20 EGO22215.1 - 0.1 12.9 0.1 49 4.5 0.0 4.8 7 0 0 7 7 5 0 PPR repeat TPR_2 PF07719.17 EGO22215.1 - 0.93 9.8 7.8 56 4.2 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Ras PF00071.22 EGO22216.1 - 2.2e-50 170.5 0.0 2.5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO22216.1 - 2.1e-20 73.1 0.0 2.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO22216.1 - 2.2e-06 27.2 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO22216.1 - 0.0018 17.7 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Skp1_POZ PF03931.15 EGO22216.1 - 0.009 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain MMR_HSR1 PF01926.23 EGO22216.1 - 0.033 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO22216.1 - 0.096 12.6 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ADH_zinc_N PF00107.26 EGO22217.1 - 1.4e-16 60.7 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO22217.1 - 0.00033 21.7 0.0 0.00072 20.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EGO22217.1 - 0.0042 17.0 0.1 0.0078 16.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO22217.1 - 0.0094 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_N PF08240.12 EGO22217.1 - 0.029 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.6 EGO22217.1 - 0.094 13.2 0.0 0.74 10.3 0.0 2.2 1 1 0 1 1 1 0 CoA binding domain Brix PF04427.18 EGO22218.1 - 2.4e-25 89.8 0.0 3.7e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 EGO22219.1 - 1.9e-64 217.6 0.0 3.5e-64 216.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22219.1 - 1.1e-36 126.5 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO22219.1 - 1.9e-07 30.7 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO22219.1 - 7.7e-05 21.6 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO22219.1 - 0.0004 19.8 1.7 0.0018 17.7 0.1 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO22219.1 - 0.001 19.1 0.5 0.0034 17.3 0.4 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO22219.1 - 0.028 13.4 0.2 0.043 12.7 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGO22219.1 - 0.084 12.5 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 EGO22219.1 - 0.1 11.5 0.2 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Guanylate_kin PF00625.21 EGO22220.1 - 4.5e-65 218.7 0.0 6.1e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EGO22220.1 - 6.1e-06 26.7 0.0 2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGO22220.1 - 0.00011 22.4 0.0 0.00048 20.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO22220.1 - 0.0066 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGO22220.1 - 0.0099 16.2 0.0 0.027 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGO22220.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 EGO22220.1 - 0.03 14.9 0.0 0.069 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGO22220.1 - 0.043 13.9 0.0 0.072 13.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GAT PF03127.14 EGO22220.1 - 0.046 14.0 0.1 0.076 13.3 0.1 1.3 1 0 0 1 1 1 0 GAT domain AAA PF00004.29 EGO22220.1 - 0.063 13.7 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGO22220.1 - 0.066 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EGO22220.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 NTPase Septin PF00735.18 EGO22220.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin dNK PF01712.19 EGO22220.1 - 0.16 11.8 0.1 6 6.7 0.0 2.6 2 1 1 3 3 3 0 Deoxynucleoside kinase DUF1640 PF07798.11 EGO22221.1 - 1.1e-61 207.9 12.1 1.3e-61 207.7 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DotU PF09850.9 EGO22221.1 - 0.003 17.3 1.3 2.6 7.7 0.0 3.1 3 0 0 3 3 3 1 Type VI secretion system protein DotU KIAA1430 PF13879.6 EGO22221.1 - 0.14 13.0 6.5 0.21 12.4 6.5 1.4 1 0 0 1 1 1 0 KIAA1430 homologue DUF1192 PF06698.11 EGO22221.1 - 0.58 10.2 6.6 0.94 9.6 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 EGO22221.1 - 0.67 10.4 5.9 0.37 11.2 1.2 2.6 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 EGO22221.1 - 1.2 9.5 11.0 0.29 11.5 5.3 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 EGO22221.1 - 8.4 7.1 8.3 18 6.0 4.6 2.6 1 1 2 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 EGO22221.1 - 9.4 6.4 12.7 1.1 9.5 2.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DSPc PF00782.20 EGO22222.1 - 1.5e-32 112.2 0.0 2.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGO22222.1 - 3.2e-05 23.6 0.1 5.7e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EGO22222.1 - 0.00026 20.7 0.1 0.00041 20.0 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGO22222.1 - 0.0022 18.3 0.1 0.0043 17.3 0.1 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Nitr_red_bet_C PF14711.6 EGO22222.1 - 0.014 15.1 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal ABC_membrane PF00664.23 EGO22223.1 - 2.8e-65 220.7 41.9 5.7e-34 118.0 13.0 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO22223.1 - 7.3e-53 178.8 0.0 3.2e-31 108.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO22223.1 - 1e-07 31.6 0.0 0.061 12.8 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO22223.1 - 2.8e-05 24.2 0.6 0.25 11.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGO22223.1 - 3.5e-05 23.7 1.4 2.6 7.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO22223.1 - 0.00013 21.7 1.2 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO22223.1 - 0.0002 21.8 0.1 0.45 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO22223.1 - 0.0007 19.5 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF4574 PF15141.6 EGO22223.1 - 0.0008 19.3 0.1 0.0024 17.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Zeta_toxin PF06414.12 EGO22223.1 - 0.0019 17.5 0.1 0.31 10.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin 60KD_IMP PF02096.20 EGO22223.1 - 0.0026 17.7 6.5 0.0026 17.7 6.5 2.9 3 0 0 3 3 3 1 60Kd inner membrane protein AAA_23 PF13476.6 EGO22223.1 - 0.0072 16.8 5.4 1.1 9.7 0.1 2.9 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 EGO22223.1 - 0.0081 15.2 0.0 4.1 6.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 EGO22223.1 - 0.026 14.1 1.4 0.36 10.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EGO22223.1 - 0.041 13.1 1.0 0.82 8.8 0.2 2.9 2 1 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 EGO22223.1 - 0.059 13.4 0.4 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 EGO22223.1 - 0.07 12.1 0.1 8.1 5.3 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGO22223.1 - 0.14 11.8 0.3 6.1 6.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 EGO22223.1 - 0.15 11.8 0.6 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 EGO22223.1 - 0.15 11.9 0.8 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EGO22223.1 - 0.29 11.0 1.0 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 EGO22223.1 - 0.39 11.0 2.3 7.3 6.9 0.2 3.2 2 1 0 2 2 2 0 AAA domain Peptidase_C12 PF01088.21 EGO22224.1 - 3.2e-56 190.4 0.0 3.9e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HECT PF00632.25 EGO22225.1 - 4.8e-78 262.7 0.0 7.3e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EGO22225.1 - 0.004 17.1 0.5 0.3 11.2 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Aminotran_3 PF00202.21 EGO22226.1 - 1.2e-77 261.3 0.1 1.5e-77 261.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SelR PF01641.18 EGO22227.1 - 2.1e-49 166.6 0.1 2.6e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EGO22227.1 - 0.012 15.6 0.4 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.14 EGO22227.1 - 0.025 14.8 0.4 0.12 12.6 0.4 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tnp_zf-ribbon_2 PF13842.6 EGO22227.1 - 0.058 14.2 0.2 5.1 8.0 0.0 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF678 PF05077.12 EGO22227.1 - 0.11 12.6 0.1 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) ADD_ATRX PF17981.1 EGO22227.1 - 0.17 11.8 0.3 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-ribbon_3 PF13248.6 EGO22227.1 - 2.6 7.6 4.8 17 5.0 0.1 3.0 4 0 0 4 4 4 0 zinc-ribbon domain Tropomyosin_1 PF12718.7 EGO22228.1 - 4.9e-51 172.6 33.0 5.7e-51 172.4 33.0 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EGO22228.1 - 8.3e-13 48.3 32.4 3.3e-06 26.7 15.6 2.9 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 EGO22228.1 - 0.00012 22.1 32.3 0.0082 16.2 9.7 2.8 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 EGO22228.1 - 0.00043 20.6 14.5 0.00043 20.6 14.5 2.3 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tup_N PF08581.10 EGO22228.1 - 0.00044 20.5 4.0 0.00044 20.5 4.0 2.7 1 1 2 3 3 3 1 Tup N-terminal KELK PF15796.5 EGO22228.1 - 0.00048 20.5 5.7 0.00048 20.5 5.7 3.7 1 1 1 3 3 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 EGO22228.1 - 0.00096 19.2 5.5 0.00096 19.2 5.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) GAS PF13851.6 EGO22228.1 - 0.0017 17.8 31.5 0.027 13.8 10.6 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 EGO22228.1 - 0.0018 18.7 33.6 0.23 11.9 15.6 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) FliD_C PF07195.12 EGO22228.1 - 0.012 15.0 17.2 0.13 11.6 7.4 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.8 EGO22228.1 - 0.018 14.4 26.5 0.27 10.5 13.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HrpB7 PF09486.10 EGO22228.1 - 0.018 15.4 21.2 0.19 12.1 6.7 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) CLZ PF16526.5 EGO22228.1 - 0.023 15.1 23.9 0.31 11.4 3.5 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EzrA PF06160.12 EGO22228.1 - 0.04 12.1 26.7 0.0078 14.4 10.6 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FliJ PF02050.16 EGO22228.1 - 0.042 14.1 26.4 0.079 13.2 7.3 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein Lebercilin PF15619.6 EGO22228.1 - 0.043 13.5 29.8 0.057 13.1 25.7 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 EGO22228.1 - 0.046 13.2 29.6 0.057 12.9 29.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 EGO22228.1 - 0.051 13.8 31.3 0.04 14.1 15.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 EGO22228.1 - 0.06 13.4 0.8 0.06 13.4 0.8 2.6 1 1 1 2 2 2 0 Laminin Domain II HHV-5_US34A PF17087.5 EGO22228.1 - 0.08 13.1 0.9 0.08 13.1 0.9 2.3 2 1 1 3 3 1 0 Herpesvirus US34A protein family BLOC1_2 PF10046.9 EGO22228.1 - 0.089 13.1 22.8 1.4 9.3 5.7 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 EGO22228.1 - 0.092 12.1 23.1 0.16 11.3 23.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HGD-D PF06050.13 EGO22228.1 - 0.094 12.5 2.8 0.096 12.4 2.2 1.4 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DHR10 PF18595.1 EGO22228.1 - 0.099 12.7 33.9 0.32 11.0 12.5 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Transketolase_N PF00456.21 EGO22228.1 - 0.11 11.5 7.8 0.13 11.2 7.8 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain ATG16 PF08614.11 EGO22228.1 - 0.12 12.6 30.1 0.55 10.4 16.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EGO22228.1 - 0.12 12.8 38.0 0.24 11.9 22.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 EGO22228.1 - 0.13 12.4 32.3 0.84 9.8 11.1 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EGO22228.1 - 0.14 12.2 33.9 7.6 6.6 22.1 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EGO22228.1 - 0.15 12.1 26.3 2.2 8.4 15.0 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 EGO22228.1 - 0.2 11.5 35.0 1.1 9.0 33.9 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Cep57_CLD_2 PF14197.6 EGO22228.1 - 0.2 11.8 20.1 18 5.5 0.1 4.2 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 EGO22228.1 - 0.21 12.0 27.3 0.24 11.8 24.6 1.9 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 EGO22228.1 - 0.24 11.6 17.3 1.6 8.9 5.7 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EGO22228.1 - 0.26 11.3 34.5 0.1 12.6 16.2 3.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding T3SSipB PF16535.5 EGO22228.1 - 0.29 11.6 22.4 0.61 10.5 16.9 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF2408 PF10303.9 EGO22228.1 - 0.33 11.5 21.9 1.2 9.7 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF724 PF05266.14 EGO22228.1 - 0.46 10.3 29.2 1.7 8.5 10.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) WXG100 PF06013.12 EGO22228.1 - 0.61 10.4 14.2 1.7 9.0 0.4 3.9 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF3584 PF12128.8 EGO22228.1 - 0.65 7.4 28.7 1.1 6.6 28.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.19 EGO22228.1 - 0.69 7.7 16.8 0.87 7.4 16.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 EGO22228.1 - 0.71 10.1 27.1 1.2 9.3 13.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding HalX PF08663.10 EGO22228.1 - 0.74 10.2 25.3 5.1 7.5 0.7 4.3 3 1 1 4 4 4 0 HalX domain DUF4061 PF13270.6 EGO22228.1 - 0.75 10.2 19.2 1.4 9.3 4.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) DUF745 PF05335.13 EGO22228.1 - 0.96 9.1 22.2 1.5 8.5 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) GrpE PF01025.19 EGO22228.1 - 0.96 9.1 32.4 1.3 8.6 3.8 4.0 1 1 3 4 4 4 0 GrpE Seryl_tRNA_N PF02403.22 EGO22228.1 - 1 9.6 29.0 0.34 11.1 14.9 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EGO22228.1 - 1.1 8.1 31.5 1.6 7.5 17.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.16 EGO22228.1 - 1.3 7.8 16.2 1.9 7.3 16.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ax_dynein_light PF10211.9 EGO22228.1 - 1.3 8.9 28.5 1.6 8.6 11.9 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4164 PF13747.6 EGO22228.1 - 1.5 9.2 25.0 0.95 9.8 9.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Csm1_N PF18504.1 EGO22228.1 - 1.6 9.1 27.4 1.1 9.6 9.1 4.0 1 1 2 3 3 3 0 Csm1 N-terminal domain AAA_13 PF13166.6 EGO22228.1 - 1.7 7.2 24.5 1.3 7.6 10.1 2.0 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 EGO22228.1 - 1.7 9.2 12.6 5.9 7.4 0.8 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BST2 PF16716.5 EGO22228.1 - 1.8 9.2 23.5 0.41 11.3 7.9 2.7 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Lectin_N PF03954.14 EGO22228.1 - 1.8 8.3 12.8 2.8 7.7 3.3 2.7 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.6 EGO22228.1 - 1.8 9.0 17.7 4.6 7.7 13.8 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Sec34 PF04136.15 EGO22228.1 - 1.9 8.3 13.8 0.077 12.9 3.0 2.3 1 1 2 3 3 3 0 Sec34-like family DUF948 PF06103.11 EGO22228.1 - 2 8.7 12.5 2.2 8.6 2.3 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) MAD PF05557.13 EGO22228.1 - 2.2 6.5 29.4 0.33 9.2 17.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Laminin_I PF06008.14 EGO22228.1 - 2.3 7.9 24.5 2.2 7.9 6.6 2.1 1 1 0 2 2 2 0 Laminin Domain I KxDL PF10241.9 EGO22228.1 - 2.3 8.5 19.1 2.7 8.3 4.2 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein Fzo_mitofusin PF04799.13 EGO22228.1 - 2.4 7.7 15.5 0.48 10.0 4.4 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF812 PF05667.11 EGO22228.1 - 2.5 6.9 29.4 4.8 6.0 29.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 EGO22228.1 - 3 5.9 28.6 1.7 6.7 10.9 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil TINF2_N PF14973.6 EGO22228.1 - 3 8.2 13.2 0.16 12.3 3.8 2.4 1 1 2 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Med21 PF11221.8 EGO22228.1 - 3.1 8.1 20.7 20 5.4 20.7 2.2 1 1 0 1 1 1 0 Subunit 21 of Mediator complex XhlA PF10779.9 EGO22228.1 - 3.6 7.9 26.8 4.8 7.5 1.5 4.1 1 1 4 5 5 5 0 Haemolysin XhlA UPF0242 PF06785.11 EGO22228.1 - 3.7 7.6 29.8 3 7.9 15.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 EGO22228.1 - 4 8.2 19.3 3.2 8.5 6.5 2.9 1 1 2 3 3 3 0 Occludin homology domain Alanine_zipper PF11839.8 EGO22228.1 - 5.9 7.3 20.5 3.4 8.1 5.8 3.6 2 2 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF4201 PF13870.6 EGO22228.1 - 5.9 6.6 26.9 82 2.9 8.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) LIN37 PF15306.6 EGO22228.1 - 6.6 6.9 12.7 11 6.2 12.7 1.4 1 1 0 1 1 1 0 LIN37 Snapin_Pallidin PF14712.6 EGO22228.1 - 6.9 7.2 18.7 3.1 8.3 9.8 3.0 1 1 2 3 3 3 0 Snapin/Pallidin NAD_binding_4 PF07993.12 EGO22228.1 - 7.5 5.6 11.3 4.2 6.5 1.9 2.2 1 1 1 2 2 2 0 Male sterility protein YscO PF07321.12 EGO22228.1 - 8.4 6.3 34.1 2.9 7.9 13.3 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO EHN PF06441.12 EGO22228.1 - 8.4 6.8 11.0 3.6e+02 1.6 8.9 2.6 1 1 1 2 2 1 0 Epoxide hydrolase N terminus Atg14 PF10186.9 EGO22228.1 - 8.5 5.4 24.3 6.8 5.7 8.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cluap1 PF10234.9 EGO22228.1 - 8.6 5.7 23.9 13 5.1 8.5 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 HOOK PF05622.12 EGO22228.1 - 8.8 4.3 30.9 41 2.1 28.5 1.9 1 1 0 1 1 1 0 HOOK protein DUF2203 PF09969.9 EGO22228.1 - 8.8 7.1 22.3 2 9.2 6.5 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) ApoO PF09769.9 EGO22228.1 - 9.1 6.3 7.0 7.4e+02 0.1 7.0 3.2 1 1 0 1 1 1 0 Apolipoprotein O DUF641 PF04859.12 EGO22228.1 - 9.4 6.6 21.5 1.1 9.7 4.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4094 PF13334.6 EGO22228.1 - 9.8 6.7 15.7 0.25 11.8 3.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) FUSC PF04632.12 EGO22228.1 - 9.9 4.6 5.7 11 4.4 5.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2408 PF10303.9 EGO22229.1 - 3.2e-62 209.0 5.4 3.4e-42 144.2 0.1 5.1 4 1 1 5 5 5 5 Protein of unknown function (DUF2408) ZapA PF05164.13 EGO22229.1 - 0.03 14.8 0.1 0.32 11.4 0.0 2.6 2 0 0 2 2 2 0 Cell division protein ZapA DED PF01335.21 EGO22229.1 - 0.048 14.0 0.7 1.4 9.3 0.0 3.1 3 0 0 3 3 3 0 Death effector domain DUF4763 PF15960.5 EGO22229.1 - 0.38 10.0 4.5 2.4 7.4 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Trns_repr_metal PF02583.17 EGO22229.1 - 0.38 11.1 2.1 5.5 7.4 0.0 3.5 5 0 0 5 5 5 0 Metal-sensitive transcriptional repressor Mo25 PF08569.11 EGO22229.1 - 0.45 9.8 3.2 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 Mo25-like PQ-loop PF04193.14 EGO22230.1 - 2.1e-34 117.1 7.4 8.7e-20 70.3 1.3 2.9 2 1 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EGO22230.1 - 3.9e-06 27.7 5.7 0.0019 19.1 1.8 2.7 1 1 1 2 2 2 2 ER lumen protein retaining receptor HGWP PF03578.15 EGO22230.1 - 0.095 12.2 0.8 0.28 10.7 0.8 1.8 1 0 0 1 1 1 0 HGWP repeat Helicase_C PF00271.31 EGO22232.1 - 4.3e-18 65.7 0.0 7.4e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO22232.1 - 2.5e-14 53.5 0.0 4.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 EGO22232.1 - 0.00038 19.4 0.0 0.00051 19.0 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ERCC3_RAD25_C PF16203.5 EGO22232.1 - 0.00039 19.7 0.0 0.00067 18.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGO22232.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RcbX PF02341.15 EGO22232.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 RbcX protein Mito_fiss_reg PF05308.11 EGO22233.1 - 0.0046 17.1 0.0 0.0057 16.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator Kei1 PF08552.11 EGO22234.1 - 1.5e-55 188.0 4.5 2.4e-55 187.4 4.5 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2781 PF10914.8 EGO22234.1 - 0.04 14.3 0.8 0.079 13.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) IF4E PF01652.18 EGO22235.1 - 1.4e-55 187.4 0.1 1.8e-55 187.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MMS19_C PF12460.8 EGO22236.1 - 4.1e-122 408.3 1.8 1.9e-119 399.5 1.2 3.1 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EGO22236.1 - 4e-94 315.0 0.1 1.6e-91 306.5 0.0 3.3 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EGO22236.1 - 2.5e-10 40.7 0.1 0.00025 21.5 0.0 6.3 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 EGO22236.1 - 4.6e-10 39.8 1.2 0.0077 16.6 0.0 5.5 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.22 EGO22236.1 - 9.5e-07 28.6 5.0 0.013 15.7 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat Tctex-1 PF03645.13 EGO22236.1 - 0.0037 17.5 0.0 1.6 9.0 0.0 2.9 2 0 0 2 2 2 1 Tctex-1 family Arm PF00514.23 EGO22236.1 - 0.0097 15.9 4.5 12 6.1 0.0 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGO22236.1 - 0.22 11.6 5.1 1.9 8.5 0.1 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Rcd1 PF04078.13 EGO22237.1 - 1.3e-124 414.7 4.5 1.5e-124 414.5 4.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like UAA PF08449.11 EGO22238.1 - 3e-76 256.5 9.2 3.4e-76 256.4 9.2 1.0 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EGO22238.1 - 0.0022 17.0 1.8 0.0032 16.5 1.7 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGO22238.1 - 0.0031 17.7 26.9 0.17 12.1 7.9 2.5 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EGO22238.1 - 0.17 11.0 7.3 0.23 10.6 7.3 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter Nup35_RRM PF05172.13 EGO22239.1 - 4.8e-09 36.1 0.0 2.2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGO22239.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cation_efflux PF01545.21 EGO22240.1 - 1.8e-40 138.8 29.6 1.8e-40 138.8 29.6 3.3 2 2 0 2 2 2 1 Cation efflux family Connexin PF00029.19 EGO22240.1 - 0.28 10.9 1.3 0.78 9.5 0.1 2.2 2 0 0 2 2 2 0 Connexin V_ATPase_I PF01496.19 EGO22240.1 - 1.7 6.4 12.9 22 2.8 13.9 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fungal_trans PF04082.18 EGO22241.1 - 3e-14 52.7 0.8 5.4e-14 51.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_ab PF00006.25 EGO22242.1 - 2.2e-73 246.4 0.0 3.7e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGO22242.1 - 8.8e-43 145.6 0.0 1.4e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGO22242.1 - 9.9e-18 64.4 1.2 2.3e-17 63.3 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 EGO22243.1 - 5.5e-24 84.4 0.5 6.7e-24 84.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 EGO22243.1 - 0.056 13.5 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 UvrA interaction domain FF PF01846.19 EGO22244.1 - 5.9e-30 103.2 6.4 3.6e-11 43.1 0.0 6.0 5 1 1 6 6 6 4 FF domain WW PF00397.26 EGO22244.1 - 2.6e-11 43.4 16.0 2.1e-06 27.7 4.7 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EGO22244.1 - 0.079 13.7 6.0 0.87 10.3 0.2 4.3 4 1 0 4 4 4 0 p190-A and -B Rho GAPs FF domain PHF5 PF03660.14 EGO22245.1 - 1.9e-52 175.9 7.9 2.1e-52 175.7 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGO22245.1 - 0.038 11.9 4.8 0.042 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EGO22245.1 - 0.42 10.7 15.0 1.6 8.8 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EGO22245.1 - 2 8.8 17.7 0.37 11.1 2.7 2.6 1 1 1 2 2 2 0 C1 domain ZZ PF00569.17 EGO22246.1 - 7.7e-17 60.8 57.8 2.9e-07 30.2 2.5 6.2 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.24 EGO22246.1 - 6.1e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 EGO22246.1 - 2.3e-06 27.8 49.6 0.023 15.0 2.4 5.9 6 0 0 6 6 6 5 C1 domain Cwf_Cwc_15 PF04889.12 EGO22247.1 - 0.0028 17.4 0.6 0.0032 17.3 0.6 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Mus7 PF09462.10 EGO22248.1 - 1.1e-43 150.1 0.0 1.4e-43 149.7 0.0 1.0 1 0 0 1 1 1 1 Mus7/MMS22 family Phage_endo_I PF05367.11 EGO22249.1 - 0.065 12.8 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage endonuclease I DUF1771 PF08590.10 EGO22250.1 - 9.4e-15 54.7 4.5 9.4e-15 54.7 4.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Torus PF16131.5 EGO22250.1 - 1.5e-06 28.9 3.6 3.8e-05 24.3 0.1 2.4 1 1 1 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EGO22250.1 - 2.6e-06 27.3 9.1 0.00023 21.1 1.8 2.8 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 EGO22250.1 - 3.7e-06 27.2 0.1 1.1e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 EGO22250.1 - 7.7e-06 25.7 6.6 0.00081 19.2 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGO22250.1 - 0.00081 19.8 6.4 0.13 12.7 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGO22250.1 - 0.0018 18.0 12.9 0.069 13.0 1.0 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGO22250.1 - 0.0048 17.1 3.5 1.7 8.9 0.2 2.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 EGO22250.1 - 0.0073 16.0 4.9 0.1 12.4 1.1 2.5 2 0 0 2 2 2 1 Putative zinc-finger domain HBS1_N PF08938.10 EGO22250.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus FA_hydroxylase PF04116.13 EGO22251.1 - 4.2e-23 82.1 12.5 4.2e-23 82.1 12.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DDE_3 PF13358.6 EGO22254.1 - 7e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L37ae PF01780.19 EGO22256.1 - 5.6e-41 138.5 10.9 6.3e-41 138.4 10.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EGO22256.1 - 0.00079 19.5 3.0 0.0011 19.0 3.0 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EGO22256.1 - 0.0027 17.7 1.2 0.0044 17.0 1.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.12 EGO22256.1 - 0.0085 15.9 0.7 0.012 15.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-FCS PF06467.14 EGO22256.1 - 0.046 13.7 2.1 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rsm1 PF08600.10 EGO22256.1 - 0.066 13.4 0.7 0.098 12.8 0.6 1.3 1 1 0 1 1 1 0 Rsm1-like zf-BED PF02892.15 EGO22256.1 - 0.091 12.8 4.3 4.4 7.4 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 EGO22256.1 - 0.096 13.0 2.8 1.2 9.5 3.1 2.0 1 1 0 1 1 1 0 C1 domain zf-ribbon_3 PF13248.6 EGO22256.1 - 0.12 11.9 1.6 7.6 6.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 EGO22256.1 - 0.25 11.8 4.6 2.3 8.8 0.8 2.3 1 1 1 2 2 2 0 Zinc-finger double domain DUF3328 PF11807.8 EGO22257.1 - 2e-09 37.5 9.5 4.5e-08 33.2 9.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EGO22258.1 - 2.1e-11 44.1 1.4 2.6e-11 43.7 0.2 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3328) Acetyltransf_7 PF13508.7 EGO22259.1 - 7.6e-08 32.7 0.0 3.4e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO22259.1 - 8.9e-05 22.7 0.0 0.00019 21.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO22259.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO22259.1 - 0.029 14.5 0.0 0.13 12.4 0.0 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO22259.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GCFC PF07842.12 EGO22261.1 - 1.7e-81 273.9 11.1 2.7e-81 273.2 11.1 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGO22261.1 - 3.3e-12 46.1 2.3 6.6e-12 45.1 2.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGO22261.1 - 1.1e-06 28.6 0.8 1.1e-06 28.6 0.8 2.2 3 0 0 3 3 3 1 G-patch domain WD40 PF00400.32 EGO22262.1 - 6.8e-10 39.4 1.0 2e-05 25.2 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO22262.1 - 0.001 19.3 0.0 0.0031 17.8 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO22262.1 - 0.044 12.7 0.0 0.075 12.0 0.0 1.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CSS-motif PF12792.7 EGO22263.1 - 0.052 13.0 1.0 0.093 12.2 1.0 1.4 1 0 0 1 1 1 0 CSS motif domain associated with EAL ANTH PF07651.16 EGO22263.1 - 0.055 12.4 0.2 0.08 11.9 0.2 1.2 1 0 0 1 1 1 0 ANTH domain Tim44 PF04280.15 EGO22264.1 - 1.9e-34 118.9 0.4 3.9e-34 117.9 0.4 1.6 1 0 0 1 1 1 1 Tim44-like domain DUF3813 PF12758.7 EGO22264.1 - 0.0059 16.9 5.6 0.48 10.8 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3813) Ribosomal_S20p PF01649.18 EGO22264.1 - 0.02 15.5 3.6 1.6 9.4 0.2 2.9 2 1 1 3 3 3 0 Ribosomal protein S20 DHquinase_II PF01220.19 EGO22264.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Dehydroquinase class II PIN_8 PF18476.1 EGO22264.1 - 0.23 11.3 4.6 0.45 10.3 3.3 2.1 2 1 0 2 2 2 0 PIN like domain AIP3 PF03915.13 EGO22264.1 - 0.4 9.7 6.1 0.26 10.3 0.4 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 DUF2203 PF09969.9 EGO22264.1 - 1.9 9.2 7.2 1.4 9.6 2.4 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) FAM25 PF15825.5 EGO22264.1 - 4.3 7.8 7.2 0.67 10.3 1.8 2.6 3 0 0 3 3 3 0 FAM25 family Cyto_heme_lyase PF01265.17 EGO22265.1 - 8e-83 278.4 8.8 3.6e-81 273.0 8.8 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase gag-asp_proteas PF13975.6 EGO22266.1 - 0.0056 17.2 0.0 0.0067 17.0 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO22266.1 - 0.02 14.7 0.0 0.44 10.3 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO22266.1 - 0.046 14.4 0.0 0.056 14.1 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 EGO22267.1 - 4.7e-08 33.2 0.1 4.7e-08 33.2 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO22267.1 - 6.2e-07 29.2 4.8 1.3e-06 28.2 4.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO22267.1 - 0.059 13.4 2.6 0.22 11.5 2.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Sugar_tr PF00083.24 EGO22272.1 - 6.7e-129 430.7 29.7 7.6e-129 430.5 29.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO22272.1 - 2.8e-24 85.7 61.4 1.8e-22 79.8 36.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dak1 PF02733.17 EGO22273.1 - 1.3e-107 359.3 0.1 2e-107 358.7 0.1 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGO22273.1 - 2e-38 132.0 1.6 2.8e-38 131.5 1.6 1.2 1 0 0 1 1 1 1 DAK2 domain UCH PF00443.29 EGO22274.1 - 7.3e-70 235.4 0.0 9.9e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGO22274.1 - 1.4e-13 51.2 0.2 6.2e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 EGO22274.1 - 9.2e-13 48.5 0.0 7.6e-05 22.4 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF1712 PF08217.11 EGO22275.1 - 2.1e-22 79.4 0.0 2.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-CCCH PF00642.24 EGO22276.1 - 1.7e-08 34.2 21.0 4.5e-05 23.2 0.4 4.6 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO22276.1 - 0.14 12.3 21.3 1.7 8.8 1.3 5.1 5 1 0 5 5 5 0 Zinc finger domain Torus PF16131.5 EGO22276.1 - 1.5 9.6 22.4 1.7 9.4 1.1 4.7 2 1 3 5 5 5 0 Torus domain MSP1_C PF07462.11 EGO22276.1 - 2.5 6.7 6.0 3.7 6.1 6.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-CCCH_3 PF15663.5 EGO22276.1 - 6 7.1 10.8 38 4.6 6.4 2.9 1 1 1 2 2 2 0 Zinc-finger containing family CDC45 PF02724.14 EGO22276.1 - 8.5 4.5 10.9 11 4.1 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EGO22276.1 - 9.8 5.4 17.0 0.052 12.9 8.5 1.6 2 0 0 2 2 2 0 NOA36 protein Sec1 PF00995.23 EGO22277.1 - 2.2e-129 433.3 0.0 2.6e-129 433.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.29 EGO22278.1 - 6.8e-42 143.0 0.0 1.3e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO22278.1 - 4.2e-11 42.6 0.7 9e-11 41.6 0.1 1.9 3 0 0 3 3 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGO22278.1 - 5.2e-11 42.2 0.2 1.2e-10 41.0 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO22278.1 - 1.2e-07 32.3 0.0 6.5e-05 23.4 0.1 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EGO22278.1 - 5e-07 29.8 0.1 7.5e-06 26.0 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO22278.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGO22278.1 - 1.2e-05 25.4 0.0 4.7e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGO22278.1 - 0.00013 22.3 0.1 0.0043 17.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EGO22278.1 - 0.0016 19.0 0.3 0.0068 17.0 0.0 2.2 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EGO22278.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 EGO22278.1 - 0.002 17.7 0.1 0.0081 15.8 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 EGO22278.1 - 0.0027 16.9 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGO22278.1 - 0.0027 17.1 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGO22278.1 - 0.0036 16.8 0.0 0.0073 15.8 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGO22278.1 - 0.0039 16.4 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 EGO22278.1 - 0.004 17.2 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGO22278.1 - 0.0067 16.8 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EGO22278.1 - 0.0082 16.3 0.0 0.02 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGO22278.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGO22278.1 - 0.01 15.3 0.5 0.025 14.0 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 EGO22278.1 - 0.012 15.4 0.0 0.039 13.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGO22278.1 - 0.013 15.6 0.0 0.036 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGO22278.1 - 0.016 15.0 1.2 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGO22278.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGO22278.1 - 0.026 14.3 0.2 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGO22278.1 - 0.028 14.6 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGO22278.1 - 0.038 13.3 0.9 0.1 11.9 0.0 2.1 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 EGO22278.1 - 0.042 13.1 0.5 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EGO22278.1 - 0.049 13.2 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGO22278.1 - 0.077 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GP41 PF00517.17 EGO22278.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 1 0 Retroviral envelope protein NACHT PF05729.12 EGO22278.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain DUF3450 PF11932.8 EGO22278.1 - 0.21 10.9 0.7 0.36 10.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 EGO22278.1 - 1.2 9.6 4.7 0.17 12.3 0.6 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) GST_C PF00043.25 EGO22279.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO22279.1 - 0.043 14.0 0.0 0.056 13.7 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RCC1 PF00415.18 EGO22280.1 - 7.9e-15 55.2 2.6 8.1e-06 26.4 0.0 5.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO22280.1 - 3.9e-06 26.5 22.4 0.0057 16.4 0.8 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 EGO22280.1 - 0.11 12.4 0.3 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 F-box domain GST_N_2 PF13409.6 EGO22281.1 - 1.5e-11 44.4 0.0 2.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO22281.1 - 1.7e-11 44.3 0.0 4.7e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGO22281.1 - 0.0057 17.0 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO22281.1 - 0.0081 16.3 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO22281.1 - 0.059 13.6 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C3HC4 PF00097.25 EGO22287.1 - 4.8e-06 26.3 12.9 1.1e-05 25.2 12.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO22287.1 - 2.1e-05 24.5 8.8 2.1e-05 24.5 8.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO22287.1 - 6.8e-05 22.6 9.0 6.8e-05 22.6 9.0 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO22287.1 - 0.00066 19.8 10.7 0.0024 18.0 10.8 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGO22287.1 - 0.0019 18.5 18.8 0.0063 16.8 16.9 2.5 1 1 1 2 2 2 2 Ring finger domain ATLF PF07737.11 EGO22287.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain zf-RING_6 PF14835.6 EGO22287.1 - 0.55 10.1 5.3 1.2 9.1 5.3 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGO22287.1 - 0.61 10.1 15.8 0.5 10.4 9.0 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGO22287.1 - 4.5 7.4 11.5 10 6.2 11.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGO22287.1 - 7.9 6.8 17.5 99 3.3 17.6 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain Actin PF00022.19 EGO22288.1 - 2.4e-27 95.6 0.0 1.9e-11 43.2 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 EGO22288.1 - 1.2e-13 51.0 0.0 4.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 EGO22288.1 - 1.4e-05 24.1 0.5 6.9e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FAT PF02259.23 EGO22289.1 - 3.9e-121 404.5 8.6 3.9e-121 404.5 8.6 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGO22289.1 - 6.7e-70 235.8 0.2 2.7e-69 233.7 0.1 2.1 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGO22289.1 - 7.2e-59 198.3 1.3 1.3e-54 184.5 0.1 5.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGO22289.1 - 4e-41 139.4 0.1 4e-41 139.4 0.1 4.3 4 1 0 4 4 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EGO22289.1 - 8.9e-18 64.5 18.1 2.4e-05 24.6 0.0 10.8 10 2 1 11 11 10 4 HEAT repeats FATC PF02260.20 EGO22289.1 - 5.3e-16 58.1 0.8 1.6e-15 56.6 0.8 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EGO22289.1 - 6.6e-15 53.9 15.8 0.0054 16.9 0.0 11.1 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.6 EGO22289.1 - 2.1e-10 40.9 24.3 8.1e-05 23.0 0.1 12.1 13 1 1 14 14 13 3 HEAT-like repeat Cnd1 PF12717.7 EGO22289.1 - 6.5e-08 32.8 3.5 0.0051 16.9 0.0 5.6 6 0 0 6 6 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO22289.1 - 5.4e-07 29.4 0.9 2.3 7.7 0.0 6.7 5 3 2 7 7 7 1 CLASP N terminal TPR_19 PF14559.6 EGO22289.1 - 9.3e-07 29.3 1.7 0.0022 18.5 0.1 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Adaptin_N PF01602.20 EGO22289.1 - 2.3e-05 23.2 5.7 0.0095 14.5 1.2 4.2 1 1 1 2 2 2 1 Adaptin N terminal region IFRD PF05004.13 EGO22289.1 - 0.0016 17.6 0.2 14 4.6 0.0 5.0 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 EGO22289.1 - 0.025 14.9 5.4 0.032 14.5 0.2 4.0 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion ANAPC3 PF12895.7 EGO22289.1 - 0.06 13.6 0.2 34 4.7 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Proteasom_PSMB PF10508.9 EGO22289.1 - 0.096 11.2 0.1 1.1 7.7 0.0 2.8 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit TPR_9 PF13371.6 EGO22289.1 - 0.098 12.8 2.5 0.65 10.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO22289.1 - 0.11 12.7 8.6 0.49 10.6 0.7 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO22289.1 - 0.12 13.1 0.7 27 5.7 0.1 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22289.1 - 0.13 12.3 7.5 0.18 11.9 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat UME PF08064.13 EGO22289.1 - 0.16 11.9 9.4 0.89 9.5 0.6 5.1 4 1 1 5 5 5 0 UME (NUC010) domain TPR_1 PF00515.28 EGO22289.1 - 0.3 11.0 1.8 5.6 6.9 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO22289.1 - 0.54 11.2 7.3 2.8 9.0 0.2 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 EGO22289.1 - 3.3 7.9 5.1 36 4.6 0.0 5.1 7 0 0 7 7 4 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 EGO22289.1 - 8.3 5.4 11.3 15 4.6 0.0 5.4 6 1 1 7 7 7 0 RNAPII transcription regulator C-terminal DUF2154 PF09922.9 EGO22290.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF M20_dimer PF07687.14 EGO22291.1 - 1.6e-08 34.5 0.0 3.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EGO22291.1 - 8.2e-07 28.9 0.3 1.3e-06 28.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ-X PF14308.6 EGO22292.1 - 6.8e-65 218.4 1.1 6.8e-65 218.4 1.1 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGO22292.1 - 9.2e-25 86.6 3.3 2.3e-24 85.3 3.3 1.7 1 0 0 1 1 1 1 DnaJ domain K-box PF01486.17 EGO22292.1 - 0.098 12.8 2.8 2.1 8.6 0.3 2.9 2 0 0 2 2 2 0 K-box region Metal_resist PF13801.6 EGO22292.1 - 0.28 11.4 0.2 0.28 11.4 0.2 2.9 3 0 0 3 3 3 0 Heavy-metal resistance PspB PF06667.12 EGO22292.1 - 2.6 8.2 7.5 0.12 12.4 0.5 2.3 3 0 0 3 3 3 0 Phage shock protein B Carn_acyltransf PF00755.20 EGO22294.1 - 8.8e-183 609.1 0.0 1e-182 608.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CNH PF00780.22 EGO22295.1 - 3e-79 266.5 0.0 1.3e-78 264.4 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EGO22295.1 - 8.5e-43 145.7 0.0 1.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EGO22295.1 - 3.4e-29 102.4 0.0 8.3e-29 101.1 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EGO22295.1 - 1e-13 51.1 0.0 2.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EGO22295.1 - 0.027 14.3 0.7 0.16 11.7 0.0 2.6 3 1 0 3 3 3 0 Pleckstrin homology domain Polysacc_deac_1 PF01522.21 EGO22296.1 - 2.7e-25 88.7 0.0 9.2e-25 86.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase TPR_1 PF00515.28 EGO22298.1 - 4.2e-07 29.5 1.5 0.015 15.1 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO22298.1 - 9.1e-07 28.5 0.1 0.013 15.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO22298.1 - 0.0061 17.3 0.2 0.4 11.6 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22298.1 - 0.031 14.3 0.1 0.22 11.7 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC_3 PF13917.6 EGO22300.1 - 1.6e-05 24.8 1.6 1.6e-05 24.7 1.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO22300.1 - 5.1e-05 23.2 5.3 6.8e-05 22.8 5.3 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO22300.1 - 0.0088 15.5 1.3 0.014 14.9 1.3 1.5 1 1 0 1 1 1 1 Copper fist DNA binding domain DDE_3 PF13358.6 EGO22302.1 - 5.4e-07 29.5 0.4 7.5e-07 29.0 0.3 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease CRAL_TRIO PF00650.20 EGO22304.1 - 1.3e-27 96.5 0.0 1.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO22304.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPT PF03151.16 EGO22305.1 - 1.7e-54 185.1 17.3 2.1e-54 184.8 17.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO22305.1 - 6.1e-11 42.7 31.0 1.7e-06 28.2 13.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGO22305.1 - 4e-10 39.4 18.7 5.3e-10 39.0 18.7 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 EGO22305.1 - 4.5 7.3 7.3 11 6.1 0.1 3.2 3 0 0 3 3 3 0 Putative transmembrane family 234 Ribosomal_S4e PF00900.20 EGO22306.1 - 1.1e-36 124.6 0.1 3.1e-36 123.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGO22306.1 - 4.3e-26 90.3 0.1 7.7e-26 89.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGO22306.1 - 3.8e-21 74.9 5.8 8e-21 73.9 5.8 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGO22306.1 - 1.3e-07 31.2 0.0 3.1e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EGO22306.1 - 1.9e-05 24.4 4.3 6.1e-05 22.8 4.3 2.0 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 EGO22306.1 - 0.13 11.6 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Phage tail protein Tmemb_14 PF03647.13 EGO22308.1 - 3.1e-18 66.3 6.4 3.6e-18 66.1 6.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EGO22308.1 - 0.069 13.4 1.4 0.56 10.5 1.4 2.1 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 zf-CCHC PF00098.23 EGO22311.1 - 1.1e-05 25.3 2.7 1.8e-05 24.6 2.7 1.3 1 0 0 1 1 1 1 Zinc knuckle Pox_H7 PF04787.12 EGO22311.1 - 0.1 13.1 0.1 0.38 11.3 0.0 1.7 2 0 0 2 2 2 0 Late protein H7 DUF2781 PF10914.8 EGO22312.1 - 2.7e-42 144.6 10.1 3.1e-42 144.5 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) WD40 PF00400.32 EGO22313.1 - 5.3e-07 30.2 4.6 0.16 12.9 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 EGO22313.1 - 0.0093 14.7 0.0 0.045 12.4 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 TMIE PF16038.5 EGO22313.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 TMIE protein Glyco_hydro_47 PF01532.20 EGO22314.1 - 8.7e-134 446.8 0.0 1e-133 446.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.13 EGO22315.1 - 4.3e-29 100.9 0.6 8.1e-29 100.0 0.6 1.4 1 0 0 1 1 1 1 Erv1 / Alr family zf-ZPR1 PF03367.13 EGO22316.1 - 3.8e-107 355.1 0.0 3.7e-53 179.6 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EGO22316.1 - 0.00078 19.4 1.7 0.56 10.3 0.1 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EGO22316.1 - 0.0035 17.3 2.6 1.6 8.8 0.1 2.9 2 1 0 2 2 2 2 Double zinc ribbon DUF2688 PF10892.8 EGO22316.1 - 0.074 12.5 7.3 0.75 9.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) zinc-ribbons_6 PF07191.12 EGO22316.1 - 0.11 12.5 0.9 3.5 7.7 0.0 2.4 2 1 0 2 2 2 0 zinc-ribbons zf-C2HC5 PF06221.13 EGO22316.1 - 0.12 12.4 3.0 17 5.5 0.0 3.5 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type Zn-ribbon_8 PF09723.10 EGO22316.1 - 0.17 12.0 6.9 7.8 6.7 0.1 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EGO22316.1 - 1.9 8.3 11.4 13 5.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EGO22316.1 - 2.6 8.1 6.2 30 4.6 0.0 3.5 3 1 0 3 3 3 0 Putative transposase DNA-binding domain ADK_lid PF05191.14 EGO22316.1 - 2.6 8.1 0.0 2.6 8.1 0.0 3.6 4 0 0 4 4 4 0 Adenylate kinase, active site lid UPF0547 PF10571.9 EGO22316.1 - 4.9 7.3 6.3 88 3.3 0.5 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Rubredoxin_2 PF18073.1 EGO22316.1 - 5.7 6.8 12.9 10 5.9 0.3 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 EGO22316.1 - 6.2 6.4 10.7 7.9 6.0 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Methyltransf_28 PF02636.17 EGO22317.1 - 3.4e-40 138.4 0.0 5e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 EGO22317.1 - 4.2e-05 22.8 0.0 6.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EGO22317.1 - 0.016 16.0 0.0 0.051 14.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NepR PF18557.1 EGO22317.1 - 0.35 10.6 1.4 14 5.4 0.1 3.0 3 0 0 3 3 3 0 Anti-sigma factor NepR Methyltransf_11 PF08241.12 EGO22318.1 - 1.9e-05 25.2 0.0 3.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO22318.1 - 2.7e-05 24.8 0.0 5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO22318.1 - 0.00071 19.4 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO22318.1 - 0.12 13.1 0.0 0.21 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CRM1_repeat PF18777.1 EGO22321.1 - 0.11 12.1 0.3 0.21 11.2 0.3 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat zf-CCHC_4 PF14392.6 EGO22323.1 - 0.043 13.6 1.6 0.074 12.8 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_4 PF13837.6 EGO22325.1 - 5.7e-07 29.8 0.0 1.4e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGO22325.1 - 0.0004 21.3 0.0 0.00086 20.2 0.0 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO22325.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-HIT PF04438.16 EGO22328.1 - 1.1e-09 38.0 11.4 1.9e-09 37.2 11.4 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-ANAPC11 PF12861.7 EGO22328.1 - 0.00029 20.8 0.8 0.00059 19.8 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MYND PF01753.18 EGO22328.1 - 0.93 9.6 6.2 0.48 10.6 3.7 1.8 1 1 1 2 2 2 0 MYND finger Zip PF02535.22 EGO22329.1 - 2.7e-61 207.6 8.8 3.1e-61 207.4 8.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1673 PF07895.11 EGO22329.1 - 0.033 13.9 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Peptidase_M28 PF04389.17 EGO22330.1 - 8e-22 77.9 0.0 1.6e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGO22330.1 - 2.9e-07 30.4 0.0 7.7e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Myc_N PF01056.18 EGO22332.1 - 1 9.2 5.6 1.3 8.9 5.6 1.3 1 1 0 1 1 1 0 Myc amino-terminal region DUF3368 PF11848.8 EGO22333.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Glyco_hydro_47 PF01532.20 EGO22334.1 - 1.9e-123 412.8 0.0 1.7e-122 409.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 FGGY_N PF00370.21 EGO22335.1 - 2.2e-60 204.3 0.0 7.4e-59 199.3 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGO22335.1 - 4e-60 203.0 1.8 5.6e-60 202.5 1.8 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DEAD PF00270.29 EGO22336.1 - 8.7e-38 129.8 0.0 1.4e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO22336.1 - 3.3e-28 98.3 0.0 1.5e-27 96.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO22336.1 - 0.00047 20.2 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 EGO22336.1 - 0.019 13.3 0.1 0.026 12.8 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S10 PF00450.22 EGO22337.1 - 6.2e-63 213.6 1.3 7.2e-45 154.1 1.2 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase TPR_12 PF13424.6 EGO22338.1 - 2.9e-09 37.1 11.5 2.3e-07 31.0 0.3 4.4 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO22338.1 - 1.1e-07 31.3 3.8 0.0074 16.1 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGO22338.1 - 9.2e-06 25.0 1.3 2.6e-05 23.6 0.1 2.4 3 0 0 3 3 3 1 SHNi-TPR TPR_2 PF07719.17 EGO22338.1 - 1.5e-05 24.7 12.0 0.11 12.7 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO22338.1 - 1.7e-05 25.4 8.9 0.019 15.6 0.1 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO22338.1 - 2.7e-05 24.0 13.6 0.0049 17.0 0.2 4.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO22338.1 - 0.00016 22.1 5.6 0.0016 18.9 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22338.1 - 0.0011 18.8 13.8 0.16 12.0 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO22338.1 - 0.062 13.2 5.3 40 4.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO22338.1 - 0.071 13.5 0.0 12 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO22338.1 - 0.12 12.1 4.7 1.2 8.9 0.1 3.7 4 0 0 4 4 4 0 TPR repeat SNAP PF14938.6 EGO22338.1 - 0.31 10.4 9.6 0.55 9.6 4.3 2.8 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP AATF-Che1 PF13339.6 EGO22338.1 - 0.44 11.2 5.0 0.22 12.2 0.3 2.7 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor TPR_14 PF13428.6 EGO22338.1 - 0.63 11.0 12.7 16 6.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat FAM76 PF16046.5 EGO22338.1 - 3.2 7.0 7.7 0.56 9.5 0.1 2.0 1 1 1 2 2 2 0 FAM76 protein Aldedh PF00171.22 EGO22339.1 - 1.1e-13 50.6 4.8 1.4e-11 43.6 2.9 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Paf1 PF03985.13 EGO22340.1 - 5.4e-69 233.2 0.0 6.7e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Paf1 PH_12 PF16457.5 EGO22342.1 - 1.6e-35 122.6 0.0 3.1e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 EGO22342.1 - 6.9e-28 97.9 0.1 1.1e-27 97.3 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 EGO22342.1 - 4.5e-26 91.6 0.0 1.2e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) TUG-UBL1 PF11470.8 EGO22342.1 - 0.018 15.2 0.2 0.67 10.2 0.0 2.5 2 0 0 2 2 2 0 TUG ubiquitin-like domain DUF4327 PF14217.6 EGO22342.1 - 0.14 12.3 2.9 8.7 6.6 0.2 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4327) Aa_trans PF01490.18 EGO22345.1 - 1.6e-69 234.6 21.7 2.2e-69 234.2 21.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SUZ PF12752.7 EGO22346.1 - 1e-16 61.4 7.9 9.2e-16 58.4 7.9 2.1 1 1 0 1 1 1 1 SUZ domain R3H PF01424.22 EGO22346.1 - 0.0016 18.3 0.2 0.0033 17.4 0.2 1.5 1 0 0 1 1 1 1 R3H domain DUF3599 PF12206.8 EGO22346.1 - 0.015 15.7 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) Acyl-CoA_dh_M PF02770.19 EGO22348.1 - 0.00039 20.6 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RNA_pol_Rpb4 PF03874.16 EGO22350.1 - 1.2e-12 48.2 0.1 1.4e-12 48.0 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.20 EGO22351.1 - 7.6e-12 45.7 0.0 2.8e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase FGGY_N PF00370.21 EGO22352.1 - 5e-24 85.2 0.0 7e-16 58.5 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGO22352.1 - 3.9e-17 62.6 0.0 9.1e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MFS_5 PF05631.14 EGO22353.1 - 0.075 11.9 0.0 0.081 11.8 0.0 1.0 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM LRR_6 PF13516.6 EGO22354.1 - 0.47 10.6 4.3 2.8 8.2 0.3 3.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 EGO22354.1 - 0.53 10.1 3.7 7.6 6.4 1.0 3.0 2 0 0 2 2 2 0 Leucine rich repeat DDE_3 PF13358.6 EGO22355.1 - 0.00022 21.0 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease C_tripleX PF02363.19 EGO22355.1 - 1.8 9.1 5.0 18 5.9 0.5 2.5 2 0 0 2 2 2 0 Cysteine rich repeat Pkinase PF00069.25 EGO22358.1 - 1.2e-63 215.0 0.0 1.3e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22358.1 - 3.4e-44 151.1 0.0 4.4e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO22358.1 - 1.2e-06 27.6 0.0 1.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO22358.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO22358.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO22358.1 - 0.0023 17.9 0.4 0.042 13.8 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DSHCT PF08148.12 EGO22358.1 - 0.059 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain WaaY PF06176.11 EGO22358.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.27 EGO22359.1 - 8.1e-53 179.8 0.0 1.6e-52 178.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EGO22359.1 - 2e-37 128.6 0.6 2e-37 128.6 0.6 4.3 6 0 0 6 6 6 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EGO22359.1 - 1.1e-05 25.2 0.3 0.0001 22.0 0.1 2.7 2 0 0 2 2 2 1 FATC domain TPR_12 PF13424.6 EGO22359.1 - 0.0059 16.9 4.9 1.6 9.0 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat F-box-like PF12937.7 EGO22362.1 - 4.6e-11 42.4 0.8 1.1e-10 41.2 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO22362.1 - 0.0072 16.2 0.4 0.049 13.5 0.3 2.5 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EGO22362.1 - 0.037 14.5 3.6 4.9 7.7 0.1 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Coatomer_E PF04733.14 EGO22363.1 - 5.6e-40 137.6 0.4 6.4e-40 137.4 0.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 EGO22363.1 - 0.0071 16.4 1.8 1 9.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO22363.1 - 0.0075 16.4 1.2 0.15 12.2 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO22363.1 - 0.034 14.4 1.3 2.3 8.6 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGO22363.1 - 0.053 14.2 6.0 6.4 7.7 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 EGO22363.1 - 0.059 13.8 3.1 0.53 10.7 2.5 2.7 1 1 0 1 1 1 0 HEAT repeats TPR_19 PF14559.6 EGO22363.1 - 0.27 11.8 7.2 4.6 7.8 0.6 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat An_peroxidase PF03098.15 EGO22364.1 - 5.2e-37 127.6 0.2 2.4e-21 75.9 0.0 4.1 2 1 2 4 4 4 4 Animal haem peroxidase p450 PF00067.22 EGO22364.1 - 6e-09 35.2 0.0 1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF676 PF05057.14 EGO22365.1 - 7.9e-41 140.0 0.0 1.2e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EGO22365.1 - 1.9e-05 24.6 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 EGO22365.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGO22365.1 - 0.0081 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO22365.1 - 0.037 14.6 0.0 0.078 13.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C4H2 PF10146.9 EGO22366.1 - 0.051 13.9 1.4 0.052 13.9 0.1 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein SAP PF02037.27 EGO22368.1 - 0.039 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain Trehalase_Ca-bi PF07492.11 EGO22368.1 - 2.9 7.7 6.6 0.19 11.5 1.1 1.8 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain Pkinase_fungal PF17667.1 EGO22370.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGO22370.1 - 0.22 10.8 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PALP PF00291.25 EGO22373.1 - 1e-52 179.4 0.7 1.2e-52 179.2 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOPA_dioxygen PF08883.11 EGO22374.1 - 1.5e-38 131.2 0.3 1.9e-38 130.9 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DOPA_dioxygen PF08883.11 EGO22376.1 - 1.1e-46 157.4 0.3 1.4e-46 157.1 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ADH_N PF08240.12 EGO22379.1 - 4.1e-26 91.0 0.7 4.1e-26 91.0 0.7 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO22379.1 - 6.3e-17 61.8 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO22379.1 - 9.2e-06 25.3 0.3 0.0001 21.9 0.3 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Ank_4 PF13637.6 EGO22380.1 - 4.4e-11 43.1 0.4 1.2e-07 32.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO22380.1 - 5.3e-11 42.9 0.3 2.2e-05 25.0 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO22380.1 - 6.9e-09 35.2 0.1 0.023 15.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGO22380.1 - 8e-09 35.6 2.5 0.00077 19.8 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGO22380.1 - 2.5e-07 30.8 0.6 0.017 15.5 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Filament PF00038.21 EGO22380.1 - 0.016 14.8 0.6 0.03 13.9 0.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein KilA-N PF04383.13 EGO22380.1 - 0.052 13.4 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 KilA-N domain APC_basic PF05956.11 EGO22380.1 - 0.068 12.6 11.4 0.021 14.3 8.6 1.5 2 0 0 2 2 2 0 APC basic domain PDH PF02153.17 EGO22380.1 - 0.093 11.7 0.2 0.19 10.7 0.1 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase Phage_GPO PF05929.11 EGO22380.1 - 0.1 12.2 0.5 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2968 PF11180.8 EGO22380.1 - 0.38 10.4 6.8 0.84 9.2 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) KxDL PF10241.9 EGO22380.1 - 1.8 8.9 6.4 7.8 6.9 2.3 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein WD40 PF00400.32 EGO22381.1 - 5.8e-43 144.0 8.6 2.6e-07 31.2 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat PRP4 PF08799.11 EGO22381.1 - 2.8e-13 49.2 1.2 7.5e-13 47.8 1.2 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGO22381.1 - 5.2e-13 49.1 0.0 0.053 13.8 0.0 5.8 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO22381.1 - 0.00038 19.5 0.1 12 4.7 0.0 4.1 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO22381.1 - 0.00049 19.5 0.0 0.96 8.7 0.0 3.1 3 1 1 4 4 4 2 WD40-like domain Nbas_N PF15492.6 EGO22381.1 - 0.0055 16.1 0.1 7.4 5.8 0.0 3.2 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Adeno_knob PF00541.17 EGO22381.1 - 0.19 11.4 0.2 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 Adenoviral fibre protein (knob domain) Nup160 PF11715.8 EGO22381.1 - 2 6.9 4.8 9.8 4.7 0.1 3.4 2 1 3 5 5 5 0 Nucleoporin Nup120/160 Pkinase PF00069.25 EGO22382.1 - 4.3e-61 206.6 0.0 3.6e-60 203.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22382.1 - 6.4e-25 87.9 1.9 2.5e-19 69.6 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO22382.1 - 1.3e-05 24.3 0.1 1.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO22382.1 - 0.00068 19.1 0.3 0.0034 16.8 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO22382.1 - 0.0019 18.2 0.4 0.18 11.7 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGO22382.1 - 0.0021 17.2 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGO22382.1 - 0.0024 17.2 2.8 0.0093 15.3 0.7 2.7 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGO22382.1 - 0.015 14.1 0.4 0.029 13.1 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EGO22382.1 - 0.044 13.4 1.7 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase_C PF00433.24 EGO22382.1 - 0.054 14.2 0.6 0.18 12.6 0.6 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Smg4_UPF3 PF03467.15 EGO22383.1 - 0.094 12.7 0.0 0.099 12.7 0.0 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family Nucleocap_ssRNA PF11128.8 EGO22383.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Pkinase PF00069.25 EGO22385.1 - 1.9e-70 237.3 0.0 2.2e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22385.1 - 1.2e-53 182.0 0.0 1.4e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO22385.1 - 0.00079 18.3 0.0 0.00096 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGO22385.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.7 1 1 1 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 EGO22385.1 - 0.037 13.1 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EGO22385.1 - 0.046 13.2 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EGO22385.1 - 0.061 12.7 0.1 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO22385.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_18 PF00704.28 EGO22388.1 - 7.9e-14 52.1 1.2 1.1e-13 51.6 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4856 PF16148.5 EGO22389.1 - 0.0008 18.5 0.2 0.0011 18.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4856) DUF3836 PF12930.7 EGO22389.1 - 0.03 14.1 0.9 0.038 13.7 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Methyltransf_23 PF13489.6 EGO22390.1 - 6.1e-22 78.2 0.0 8.2e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO22390.1 - 1.4e-17 64.1 0.0 2.3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO22390.1 - 1.3e-13 51.4 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO22390.1 - 2.1e-13 50.8 0.0 5.7e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO22390.1 - 1.4e-11 44.4 0.2 0.00011 22.0 0.3 2.1 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 EGO22390.1 - 2.6e-09 36.8 0.0 1.5e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGO22390.1 - 0.00017 21.1 0.1 0.00039 19.9 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 EGO22390.1 - 0.00018 20.6 0.0 0.0022 17.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EGO22390.1 - 0.0076 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO22390.1 - 0.014 15.0 0.1 0.038 13.6 0.2 1.6 2 0 0 2 2 2 0 Methyltransferase small domain MetW PF07021.12 EGO22390.1 - 0.049 13.2 0.3 0.19 11.3 0.3 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EGO22390.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 EGO22390.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB E1-E2_ATPase PF00122.20 EGO22391.1 - 4.7e-48 163.1 6.5 7.6e-48 162.4 5.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGO22391.1 - 1.6e-31 110.2 0.3 5.7e-31 108.4 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGO22391.1 - 1.5e-27 95.8 0.1 1e-12 48.3 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGO22391.1 - 0.00057 19.7 0.7 0.0075 16.0 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4006 PF13179.6 EGO22391.1 - 0.093 12.7 0.5 0.53 10.2 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Dynactin_p22 PF07426.11 EGO22392.1 - 2.8e-05 24.0 1.1 0.00019 21.4 0.0 2.7 3 0 0 3 3 3 1 Dynactin subunit p22 PH_10 PF15411.6 EGO22393.1 - 6.6e-25 87.8 0.0 1.1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EGO22393.1 - 1.6e-05 25.2 0.0 5.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGO22393.1 - 0.00039 20.4 0.2 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EGO22393.1 - 0.00077 19.7 2.2 0.0019 18.5 2.3 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO22393.1 - 0.0029 17.5 0.4 0.006 16.5 0.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO22393.1 - 0.0048 16.9 1.9 0.012 15.6 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGO22393.1 - 0.3 10.9 2.7 0.94 9.3 2.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGO22393.1 - 2.1 8.3 3.3 15 5.6 3.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DOPA_dioxygen PF08883.11 EGO22395.1 - 2.3e-42 143.5 0.3 3.1e-42 143.1 0.3 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family NFRKB_winged PF14465.6 EGO22398.1 - 0.014 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 NFRKB Winged Helix-like DDE_Tnp_ISL3 PF01610.17 EGO22399.1 - 0.0094 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Transposase MULE PF10551.9 EGO22399.1 - 0.023 15.1 0.3 0.069 13.6 0.0 2.0 2 0 0 2 2 2 0 MULE transposase domain DOPA_dioxygen PF08883.11 EGO22400.1 - 8.4e-44 148.1 0.3 1.1e-43 147.8 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PMT PF02366.18 EGO22402.1 - 9.2e-83 277.6 17.6 9.2e-83 277.6 17.6 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGO22402.1 - 2.3e-65 219.9 2.6 2.3e-65 219.9 2.6 3.3 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGO22402.1 - 1.7e-18 67.1 0.9 2.5e-18 66.6 0.9 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EGO22402.1 - 1.5e-07 31.8 12.8 1.5e-07 31.8 12.8 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PX PF00787.24 EGO22403.1 - 6.1e-17 61.6 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 PX domain MnmE_helical PF12631.7 EGO22403.1 - 0.057 13.6 0.9 1.6 8.8 0.9 2.2 1 1 0 1 1 1 0 MnmE helical domain Vps5 PF09325.10 EGO22404.1 - 2.8e-68 230.0 8.5 3.9e-68 229.5 8.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGO22404.1 - 1.4e-24 86.3 0.0 8.6e-24 83.7 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EGO22404.1 - 0.00034 20.2 2.2 0.041 13.3 2.2 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF5486 PF17588.2 EGO22404.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) PAP_RNA-bind PF04926.15 EGO22404.1 - 0.13 11.8 0.7 0.29 10.8 0.7 1.6 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain BAR_3 PF16746.5 EGO22404.1 - 0.15 11.8 7.2 0.046 13.4 1.9 2.1 1 1 1 2 2 2 0 BAR domain of APPL family Arfaptin PF06456.13 EGO22404.1 - 0.19 11.3 4.6 1 8.9 4.6 2.0 1 1 0 1 1 1 0 Arfaptin-like domain ERG4_ERG24 PF01222.17 EGO22405.1 - 8.5e-128 426.8 25.5 9.7e-128 426.6 25.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EGO22405.1 - 0.0059 17.0 0.1 0.024 15.1 0.1 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO22405.1 - 0.016 15.6 0.2 0.016 15.6 0.2 3.5 4 0 0 4 4 4 0 Phospholipid methyltransferase DUF1295 PF06966.12 EGO22405.1 - 0.045 13.3 14.3 0.1 12.1 14.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DWNN PF08783.11 EGO22406.1 - 1.7e-30 105.1 0.4 3.8e-30 104.0 0.4 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EGO22406.1 - 7.4e-11 41.7 6.5 1.7e-10 40.5 6.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO22406.1 - 4.4e-06 26.5 1.6 4.4e-06 26.5 1.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO22406.1 - 0.0061 16.5 0.3 0.0061 16.5 0.3 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 EGO22406.1 - 0.0073 16.0 7.1 0.04 13.6 0.5 2.5 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-C3HC4_3 PF13920.6 EGO22406.1 - 0.0086 15.9 5.2 0.0086 15.9 5.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO22406.1 - 0.019 14.8 7.8 0.019 14.8 7.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3290 PF11694.8 EGO22406.1 - 0.08 12.9 2.4 0.17 11.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) zf_UBZ PF18439.1 EGO22406.1 - 0.24 11.0 6.7 0.35 10.5 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RING_UBOX PF13445.6 EGO22406.1 - 0.38 10.8 5.6 0.99 9.5 5.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO22406.1 - 0.89 9.5 7.9 2 8.3 7.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO22406.1 - 1.1 9.2 12.7 0.12 12.3 6.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain TFIIA PF03153.13 EGO22406.1 - 2.1 8.3 26.3 0.98 9.3 23.7 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 EGO22406.1 - 2.9 8.1 7.4 7.3 6.8 7.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGO22406.1 - 3.3 8.1 13.0 0.078 13.3 6.4 1.7 2 0 0 2 2 1 0 Ring finger domain zinc-ribbons_6 PF07191.12 EGO22406.1 - 6.9 6.7 9.3 6.4 6.8 4.1 2.5 2 0 0 2 2 2 0 zinc-ribbons DUF1977 PF09320.11 EGO22407.1 - 8.7e-28 96.7 0.0 1.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EGO22407.1 - 2.7e-24 85.1 0.1 5e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DNA_binding_1 PF01035.20 EGO22408.1 - 6.4e-15 55.0 0.2 8.9e-15 54.6 0.2 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain F-box-like PF12937.7 EGO22409.1 - 2.3e-05 24.2 0.1 5.6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.6 EGO22409.1 - 0.00096 18.8 0.4 0.028 14.1 0.0 2.4 1 1 1 2 2 2 1 TPR repeat MIT PF04212.18 EGO22409.1 - 0.0014 18.7 0.3 0.003 17.6 0.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EGO22409.1 - 0.0045 17.0 0.1 0.016 15.3 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box PF00646.33 EGO22409.1 - 0.009 15.9 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 EGO22409.1 - 0.019 14.8 0.1 0.064 13.1 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 EGO22409.1 - 0.025 14.6 1.3 0.06 13.4 1.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_16 PF13432.6 EGO22409.1 - 0.056 14.1 1.3 0.18 12.5 1.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat F-box_4 PF15966.5 EGO22409.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box TPR_14 PF13428.6 EGO22409.1 - 0.08 13.8 0.2 0.46 11.4 0.3 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 EGO22411.1 - 4.6e-09 36.8 4.1 0.37 11.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Clr2_transil PF16761.5 EGO22412.1 - 3.6e-26 91.8 0.1 6.8e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EGO22412.1 - 6.6e-09 36.7 0.0 1.5e-07 32.3 0.0 2.8 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 MuF_C PF18819.1 EGO22412.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain TPR_19 PF14559.6 EGO22413.1 - 1.3e-07 32.0 0.9 1.1e-05 25.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO22413.1 - 4.3e-07 30.5 0.0 2.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO22413.1 - 7.7e-06 26.3 1.2 0.71 10.8 0.1 4.5 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO22413.1 - 8.8e-05 22.3 0.0 1.9 8.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO22413.1 - 0.0078 16.1 0.1 0.066 13.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22413.1 - 0.011 15.7 0.0 2.5 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO22413.1 - 0.023 14.4 0.0 0.093 12.4 0.0 2.0 1 1 1 2 2 2 0 TPR repeat TPR_8 PF13181.6 EGO22413.1 - 0.024 14.8 0.1 1.2 9.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO22413.1 - 0.026 14.8 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGO22413.1 - 0.027 14.8 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGO22413.1 - 0.037 13.7 1.8 4 7.1 1.3 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 EGO22413.1 - 0.045 13.4 0.5 1.6 8.4 0.1 3.0 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_12 PF13424.6 EGO22413.1 - 0.05 13.9 0.2 4.6 7.6 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGO22413.1 - 0.27 11.6 1.2 1.5 9.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat MBOAT PF03062.19 EGO22414.1 - 5e-36 124.8 23.2 1.2e-35 123.6 13.6 2.8 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGO22414.1 - 2.7e-05 24.4 4.2 3.2e-05 24.1 2.3 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MafB19-deam PF14437.6 EGO22415.1 - 3.2e-23 82.0 0.0 5.5e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EGO22415.1 - 4.9e-23 80.9 0.1 6.5e-23 80.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 EGO22415.1 - 0.0035 17.4 1.8 0.057 13.5 1.8 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EGO22415.1 - 0.0037 17.4 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EGO22415.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 EGO22415.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 EGO22415.1 - 0.037 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC1 PF18769.1 EGO22415.1 - 0.041 14.1 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 APOBEC1 APOBEC2 PF18772.1 EGO22415.1 - 0.055 13.5 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 Inv-AAD PF18785.1 EGO22415.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 EGO22415.1 - 0.17 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Peptidase_S9_N PF02897.15 EGO22416.1 - 9.1e-90 301.4 4.7 1.2e-89 301.0 4.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGO22416.1 - 2.1e-52 177.7 0.0 4e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGO22416.1 - 0.012 15.5 0.8 0.15 11.9 0.8 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1890 PF09001.11 EGO22416.1 - 0.19 12.1 1.2 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) Retrotrans_gag PF03732.17 EGO22416.1 - 0.68 10.3 2.8 5.1 7.5 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein RED_N PF07808.13 EGO22417.1 - 6.3e-09 35.8 8.2 1.5e-08 34.5 8.2 1.7 1 1 0 1 1 1 1 RED-like protein N-terminal region DUF790 PF05626.11 EGO22417.1 - 0.0015 17.3 4.7 0.0018 17.1 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF790) DUF4148 PF13663.6 EGO22417.1 - 0.14 12.4 0.2 0.49 10.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) MMgT PF10270.9 EGO22418.1 - 1.6e-05 25.2 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter DUF4792 PF16040.5 EGO22418.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) Abhydrolase_1 PF00561.20 EGO22420.1 - 0.00045 19.9 0.2 0.00078 19.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO22420.1 - 0.0087 16.7 0.2 0.016 15.8 0.2 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3328 PF11807.8 EGO22421.1 - 0.00095 19.0 2.3 0.00095 19.0 2.3 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) HrcA PF01628.21 EGO22423.1 - 0.015 15.2 0.2 0.021 14.8 0.2 1.2 1 1 0 1 1 1 0 HrcA protein C terminal domain Pkinase PF00069.25 EGO22424.1 - 9.7e-09 35.0 0.0 1.4e-06 27.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22424.1 - 0.033 13.5 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase DUF5475 PF17569.2 EGO22425.1 - 0.18 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5475) zf-CCHC PF00098.23 EGO22426.1 - 7.7e-08 32.1 2.6 1.4e-07 31.3 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO22426.1 - 0.0072 16.1 0.4 0.011 15.5 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO22426.1 - 0.019 14.9 3.4 0.032 14.2 3.4 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4928 PF16280.5 EGO22426.1 - 0.028 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) zf-CCHC_5 PF14787.6 EGO22426.1 - 0.039 13.7 0.2 0.076 12.7 0.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EGO22426.1 - 0.14 11.9 1.4 0.29 10.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-binding PF00249.31 EGO22430.1 - 3.7e-39 132.7 7.8 3.5e-14 52.7 0.1 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO22430.1 - 9e-34 115.5 0.5 5.6e-12 45.7 0.0 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain zf-C2H2_aberr PF17017.5 EGO22430.1 - 9.1e-06 25.9 2.1 0.027 14.6 0.2 2.7 2 0 0 2 2 2 2 Aberrant zinc-finger SANT_DAMP1_like PF16282.5 EGO22430.1 - 0.0023 18.1 0.4 1.2 9.4 0.0 2.7 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Abhydrolase_1 PF00561.20 EGO22431.1 - 5.2e-09 36.1 0.0 6.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO22431.1 - 3.7e-06 27.7 0.0 4.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGO22431.1 - 0.00032 20.9 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EGO22431.1 - 0.001 18.4 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGO22431.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EGO22431.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dsl1_C PF11989.8 EGO22432.1 - 2.2e-10 40.6 0.1 4.5e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 EGO22432.1 - 2.6e-08 32.9 0.1 0.0014 17.3 0.1 3.3 3 0 0 3 3 3 3 Centromere/kinetochore Zw10 HAUS5 PF14817.6 EGO22432.1 - 0.073 11.8 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Rep_fac_C PF08542.11 EGO22433.1 - 4.4e-23 81.5 0.1 1.2e-22 80.2 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGO22433.1 - 2e-17 63.9 0.0 3.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGO22433.1 - 2.3e-14 53.5 0.0 9.8e-11 41.7 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EGO22433.1 - 2e-09 37.6 0.0 8.6e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EGO22433.1 - 1.9e-06 27.7 0.0 8.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EGO22433.1 - 9.6e-06 25.9 0.0 2.9e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 EGO22433.1 - 1.1e-05 25.5 0.2 6.7e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EGO22433.1 - 2.7e-05 23.5 0.0 4.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EGO22433.1 - 3.9e-05 23.6 0.1 0.00035 20.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO22433.1 - 5.5e-05 23.6 0.0 9.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EGO22433.1 - 0.00016 22.0 0.7 0.089 13.1 0.0 2.7 2 1 1 3 3 3 2 AAA domain DEAD PF00270.29 EGO22433.1 - 0.00019 21.2 0.4 0.00056 19.7 0.4 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO22433.1 - 0.00023 21.4 0.5 0.033 14.5 0.5 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO22433.1 - 0.00025 20.9 0.0 0.0006 19.6 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO22433.1 - 0.00032 20.7 0.1 0.0017 18.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 EGO22433.1 - 0.00042 20.4 0.0 0.031 14.3 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EGO22433.1 - 0.00049 19.9 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EGO22433.1 - 0.00057 19.7 0.0 0.0021 17.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 EGO22433.1 - 0.00061 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGO22433.1 - 0.0056 16.1 0.1 0.1 12.0 0.1 2.1 1 1 1 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 EGO22433.1 - 0.0056 16.2 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGO22433.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO22433.1 - 0.02 14.6 0.0 0.049 13.4 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGO22433.1 - 0.024 14.0 0.0 0.19 11.1 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.23 EGO22433.1 - 0.051 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain T2SSE PF00437.20 EGO22433.1 - 0.055 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein TPR_6 PF13174.6 EGO22433.1 - 0.056 14.1 0.9 2.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MCM PF00493.23 EGO22433.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Viral_helicase1 PF01443.18 EGO22433.1 - 0.061 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 EGO22433.1 - 0.078 12.1 0.1 1.8 7.6 0.1 2.1 1 1 0 2 2 2 0 PIF1-like helicase AAA_33 PF13671.6 EGO22433.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 EGO22434.1 - 0.00092 19.1 0.0 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO22434.1 - 0.36 10.8 2.0 7.5 6.6 0.6 2.8 2 1 0 2 2 2 0 F-box domain PET117 PF15786.5 EGO22435.1 - 1.8e-24 85.8 0.8 2e-24 85.6 0.8 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial CTD_bind PF04818.13 EGO22436.1 - 1.8e-06 28.6 0.2 6.6e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF1509 PF07420.11 EGO22437.1 - 0.67 8.9 2.3 1.1 8.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Cript PF10235.9 EGO22438.1 - 2.7e-28 98.4 3.2 2.7e-28 98.4 3.2 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EGO22438.1 - 0.00028 20.8 9.7 0.00046 20.2 5.4 2.2 1 1 1 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGO22438.1 - 0.004 16.8 13.7 2.5 7.9 0.0 3.2 3 0 0 3 3 3 3 zinc-ribbon domain DUF2039 PF10217.9 EGO22438.1 - 0.019 15.3 8.0 0.019 15.3 8.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 EGO22438.1 - 0.022 15.1 5.8 0.038 14.4 1.8 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal Gin PF10764.9 EGO22438.1 - 0.17 11.8 7.7 1.1 9.3 0.0 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf_UBZ PF18439.1 EGO22438.1 - 0.21 11.2 8.8 1.7 8.3 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF1272 PF06906.11 EGO22438.1 - 0.33 11.1 6.2 0.47 10.6 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.17 EGO22438.1 - 0.59 10.1 8.3 15 5.7 0.0 4.0 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zinc-ribbons_6 PF07191.12 EGO22438.1 - 1.5 8.8 13.5 22 5.1 13.5 2.1 1 1 0 1 1 1 0 zinc-ribbons F-box PF00646.33 EGO22439.1 - 0.11 12.5 0.4 0.28 11.1 0.4 1.7 1 0 0 1 1 1 0 F-box domain Orthoreo_P10 PF07204.11 EGO22440.1 - 0.075 13.0 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 WD40 PF00400.32 EGO22441.1 - 1.4e-18 66.9 19.2 0.014 16.3 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Methyltransf_16 PF10294.9 EGO22441.1 - 1.1e-15 57.8 0.0 2.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Ge1_WD40 PF16529.5 EGO22441.1 - 0.02 13.9 0.3 0.53 9.2 0.0 2.9 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GidB PF02527.15 EGO22441.1 - 0.036 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G SIR2 PF02146.17 EGO22442.1 - 2.4e-26 92.7 0.0 1.5e-25 90.1 0.0 1.9 1 1 0 1 1 1 1 Sir2 family DUF364 PF04016.12 EGO22442.1 - 0.1 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation Glyco_hydro_16 PF00722.21 EGO22444.1 - 1.9e-06 27.5 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PGM_PMM_I PF02878.16 EGO22445.1 - 1.5e-38 131.6 0.2 2.4e-38 131.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGO22445.1 - 1.9e-26 92.5 0.0 3.9e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGO22445.1 - 2.8e-14 53.6 0.0 1.2e-13 51.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGO22445.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Carb_kinase PF01256.17 EGO22446.1 - 2.6e-43 148.3 0.2 8e-41 140.1 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate kinase Phos_pyr_kin PF08543.12 EGO22446.1 - 0.049 13.0 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase FAM153 PF15722.5 EGO22446.1 - 0.093 13.1 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 FAM153 family FRG1 PF06229.12 EGO22447.1 - 0.0018 18.0 0.2 0.21 11.3 0.0 2.1 1 1 1 2 2 2 2 FRG1-like domain Agglutinin PF07468.11 EGO22447.1 - 0.036 14.3 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Agglutinin domain Fascin PF06268.13 EGO22447.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Fascin domain SCF PF02404.15 EGO22449.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor Coronavirus_5 PF05528.11 EGO22450.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein ANAPC4_WD40 PF12894.7 EGO22453.1 - 0.00099 19.4 0.0 0.043 14.1 0.0 2.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGO22453.1 - 0.0022 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain WD40 PF00400.32 EGO22453.1 - 0.0043 17.9 0.7 0.57 11.2 0.0 3.1 3 1 0 3 3 3 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGO22453.1 - 0.046 12.2 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF3632 PF12311.8 EGO22456.1 - 5.6e-10 39.9 0.0 1.4e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Myb_DNA-bind_3 PF12776.7 EGO22457.1 - 1.9e-09 38.4 0.1 3.1e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO22457.1 - 0.00031 21.1 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BTB PF00651.31 EGO22458.1 - 5.1e-09 36.3 0.0 1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain EamA PF00892.20 EGO22460.1 - 1.9e-12 47.5 33.3 1e-07 32.2 4.3 3.0 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 EGO22460.1 - 0.0026 17.3 9.9 0.0078 15.8 6.4 2.6 2 1 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 EGO22460.1 - 0.1 12.0 5.7 1.3 8.3 5.7 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family MFS_1 PF07690.16 EGO22462.1 - 8e-23 80.9 28.5 8e-23 80.9 28.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MMPL PF03176.15 EGO22462.1 - 2.6 6.9 7.6 3.7 6.4 1.3 2.2 2 0 0 2 2 2 0 MMPL family Ribonuc_P_40 PF08584.11 EGO22464.1 - 5.2e-29 101.4 0.0 5.6e-28 98.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit GPI2 PF06432.11 EGO22465.1 - 5.9e-87 291.7 15.2 6.6e-87 291.5 15.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Pantoate_ligase PF02569.15 EGO22466.1 - 1.3e-89 299.9 0.0 1.5e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PAP2 PF01569.21 EGO22467.1 - 1.9e-13 50.4 10.7 8.9e-13 48.2 10.7 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGO22467.1 - 0.01 16.0 0.2 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Divergent PAP2 family TIM21 PF08294.11 EGO22467.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 TIM21 Polysacc_synt_C PF14667.6 EGO22467.1 - 0.48 10.5 7.8 1.2 9.2 7.8 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain BCS1_N PF08740.11 EGO22468.1 - 4.6e-33 114.8 2.3 9e-33 113.8 2.3 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGO22468.1 - 6.8e-15 55.7 0.0 3.5e-13 50.1 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO22468.1 - 0.0011 19.4 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGO22468.1 - 0.0015 17.8 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGO22468.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EGO22468.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO22468.1 - 0.017 15.1 0.1 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EGO22468.1 - 0.022 14.7 0.0 0.091 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGO22468.1 - 0.03 14.5 0.1 0.097 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO22468.1 - 0.032 14.8 0.1 0.2 12.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO22468.1 - 0.034 14.4 0.1 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO22468.1 - 0.042 14.4 0.0 0.19 12.3 0.0 2.1 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGO22468.1 - 0.093 12.0 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGO22468.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO22468.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGO22468.1 - 0.19 12.2 0.1 0.64 10.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase F-box-like PF12937.7 EGO22469.1 - 0.14 12.0 1.6 4.5 7.2 0.1 2.7 2 1 0 2 2 2 0 F-box-like HMG_CoA_synt_C PF08540.10 EGO22470.1 - 1.6e-88 296.9 0.1 2.3e-87 293.2 0.1 2.0 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGO22470.1 - 3.9e-84 280.8 0.1 5.7e-84 280.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 EGO22470.1 - 0.0095 15.8 0.3 0.037 13.9 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EGO22470.1 - 0.062 13.5 0.0 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal VMA21 PF09446.10 EGO22473.1 - 5.1e-11 42.5 8.1 8.1e-11 41.9 8.1 1.3 1 0 0 1 1 1 1 VMA21-like domain Transposase_21 PF02992.14 EGO22475.1 - 4.4e-06 26.1 1.0 8.5e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Transposase family tnp2 DUF3632 PF12311.8 EGO22477.1 - 1.7e-11 44.9 0.0 2.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4354 PF14263.6 EGO22478.1 - 0.047 13.5 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) Ada_Zn_binding PF02805.16 EGO22478.1 - 0.11 12.5 0.3 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Metal binding domain of Ada PD40 PF07676.12 EGO22479.1 - 0.00043 20.1 0.4 0.63 10.1 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 EGO22479.1 - 0.0069 17.2 0.0 1.4 9.9 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF296 PF03479.15 EGO22479.1 - 0.052 13.9 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain WD40 PF00400.32 EGO22480.1 - 0.12 13.3 0.7 11 7.1 0.3 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.32 EGO22481.1 - 1.9e-05 25.3 23.3 0.00066 20.4 0.1 8.5 11 0 0 11 11 9 2 WD domain, G-beta repeat C2 PF00168.30 EGO22481.1 - 5.8e-05 23.3 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.6 EGO22481.1 - 0.00024 21.5 0.0 0.0047 17.3 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EGO22481.1 - 0.0014 18.6 0.0 0.0098 15.8 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGO22481.1 - 0.023 15.0 0.6 1.2 9.4 0.0 3.5 2 1 1 3 3 3 0 AAA domain Gmad1 PF10647.9 EGO22481.1 - 0.027 14.2 0.0 4 7.1 0.2 3.2 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 EGO22481.1 - 0.031 13.9 0.2 16 5.0 0.1 3.4 2 1 1 3 3 3 0 PQQ-like domain NB-ARC PF00931.22 EGO22481.1 - 0.032 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 EGO22481.1 - 0.072 13.5 0.0 0.23 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 EGO22481.1 - 0.098 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 EGO22481.1 - 0.15 12.5 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGO22481.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EGO22481.1 - 0.2 12.2 0.0 0.57 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain SHS2_Rpb7-N PF03876.17 EGO22482.1 - 1.5e-14 54.1 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGO22482.1 - 6.9e-12 45.5 0.3 1.4e-11 44.5 0.3 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EGO22482.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Sortilin-Vps10 PF15902.5 EGO22483.1 - 2.3e-292 969.3 0.5 4.6e-148 493.7 0.0 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGO22483.1 - 2e-95 317.9 21.4 3.3e-51 174.0 9.5 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGO22483.1 - 3.8e-07 29.1 41.5 0.99 9.7 0.3 11.9 11 0 0 11 11 11 3 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EGO22483.1 - 0.005 16.8 6.7 7.2 6.7 0.0 5.7 8 0 0 8 8 8 2 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 EGO22483.1 - 0.008 15.5 3.9 4 6.6 0.0 4.5 4 1 1 5 5 5 3 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.15 EGO22483.1 - 0.11 12.6 0.0 0.95 9.6 0.0 2.4 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain BNR_2 PF13088.6 EGO22483.1 - 0.19 11.0 7.9 2.1 7.5 0.0 5.3 6 2 0 6 6 6 0 BNR repeat-like domain BNR_6 PF15899.5 EGO22483.1 - 1.8 8.9 8.2 22 5.4 0.1 5.0 4 0 0 4 4 4 0 BNR-Asp box repeat RNA_pol_Rbc25 PF08292.12 EGO22484.1 - 6.6e-29 100.8 0.0 1.2e-28 99.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGO22484.1 - 1.7e-17 63.5 0.0 3.5e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Methyltransf_23 PF13489.6 EGO22485.1 - 1.1e-13 51.3 0.0 1.9e-13 50.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO22485.1 - 9.8e-13 48.6 0.0 2.3e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO22485.1 - 1.8e-12 47.8 0.0 4.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO22485.1 - 5.5e-11 43.0 0.0 2.6e-10 40.8 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO22485.1 - 7.9e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO22485.1 - 0.014 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 EGO22485.1 - 0.029 13.6 0.0 0.24 10.6 0.0 2.0 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EGO22485.1 - 0.077 14.0 0.0 0.18 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGO22485.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EGO22485.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EGO22485.1 - 0.13 11.7 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain CNH PF00780.22 EGO22486.1 - 7.4e-63 212.7 0.0 1.2e-62 212.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGO22486.1 - 2e-50 171.6 2.6 6.8e-30 104.6 0.1 3.3 2 1 1 3 3 3 3 RhoGEF domain PH_5 PF15405.6 EGO22486.1 - 2.3e-15 56.9 0.0 5.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 EGO22486.1 - 7.6e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 EGO22486.1 - 0.079 13.5 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 PH domain AA_permease PF00324.21 EGO22487.1 - 1.9e-119 399.4 38.7 2.2e-119 399.2 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO22487.1 - 3.6e-33 115.0 41.5 4.6e-33 114.7 41.5 1.1 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.32 EGO22489.1 - 1.2e-24 86.1 0.9 4.2e-07 30.6 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO22489.1 - 2.4e-06 27.7 0.6 0.12 12.6 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO22489.1 - 0.0037 16.0 0.0 1.6 7.3 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO22489.1 - 0.061 12.1 0.0 4.8 5.8 0.0 3.0 2 2 1 3 3 3 0 Nup133 N terminal like Fcf1 PF04900.12 EGO22490.1 - 6e-32 110.0 0.1 1e-31 109.3 0.1 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EGO22490.1 - 2.1e-05 24.8 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Nucleo_P87 PF07267.11 EGO22490.1 - 0.63 8.8 4.0 0.78 8.5 4.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HTH_Tnp_Tc5 PF03221.16 EGO22493.1 - 5.2e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CRISPR_Cse2 PF09485.10 EGO22494.1 - 0.079 13.5 0.7 0.24 11.9 0.2 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) START PF01852.19 EGO22496.1 - 5.3e-19 68.5 0.1 5.8e-07 29.1 0.0 4.2 4 0 0 4 4 4 3 START domain Phos_pyr_kin PF08543.12 EGO22497.1 - 5.6e-11 42.3 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGO22497.1 - 0.00012 21.5 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GST_N_2 PF13409.6 EGO22501.1 - 3.2e-09 37.0 0.0 6.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO22501.1 - 5.1e-09 36.4 0.0 2.1e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO22501.1 - 8.5e-05 22.7 0.0 0.00019 21.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO22501.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO22501.1 - 0.0044 17.3 0.2 0.049 14.0 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO22501.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4354 PF14263.6 EGO22502.1 - 0.033 14.0 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) Levi_coat PF01819.17 EGO22502.1 - 0.046 13.7 0.2 0.075 13.1 0.2 1.4 1 0 0 1 1 1 0 Levivirus coat protein BUD22 PF09073.10 EGO22504.1 - 0.0055 16.1 12.0 0.0077 15.6 12.0 1.2 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 EGO22504.1 - 0.0099 16.0 14.4 0.0099 16.0 14.4 1.4 2 0 0 2 2 2 1 YL1 nuclear protein Afi1 PF07792.12 EGO22504.1 - 0.019 15.4 1.8 0.019 15.4 1.8 1.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SR-25 PF10500.9 EGO22504.1 - 0.021 14.4 11.2 0.035 13.7 11.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGO22504.1 - 0.098 10.9 8.6 0.13 10.5 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 EGO22504.1 - 2.8 6.9 9.3 1.4 7.9 7.4 1.4 2 0 0 2 2 2 0 Pes-10 DNA_pol_phi PF04931.13 EGO22504.1 - 2.9 5.9 15.8 4.4 5.3 15.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3527 PF12043.8 EGO22506.1 - 0.0011 18.6 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) GST_N_3 PF13417.6 EGO22509.1 - 1.9e-09 37.8 0.0 9.2e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO22509.1 - 2e-08 34.4 0.0 4.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO22509.1 - 0.0085 16.3 0.0 0.019 15.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO22509.1 - 0.023 15.0 0.0 0.18 12.1 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO22509.1 - 0.035 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Actin PF00022.19 EGO22511.1 - 1.7e-115 386.0 0.0 7.3e-115 383.8 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGO22511.1 - 0.00028 19.8 0.0 0.00043 19.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Mito_carr PF00153.27 EGO22514.1 - 9.4e-07 28.7 0.0 0.061 13.2 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein Glycos_transf_2 PF00535.26 EGO22515.1 - 2.1e-19 70.0 0.0 2.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGO22515.1 - 1.1e-05 25.5 0.0 3.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 YAcAr PF10686.9 EGO22515.1 - 0.099 12.6 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family GST_N_3 PF13417.6 EGO22516.1 - 1.9e-11 44.2 0.0 7.3e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO22516.1 - 6.5e-11 42.4 0.0 3.1e-10 40.2 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO22516.1 - 3.6e-05 23.9 0.0 8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO22516.1 - 0.00035 20.8 0.0 0.0024 18.2 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO22516.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO22516.1 - 0.088 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glycos_transf_2 PF00535.26 EGO22517.1 - 7.7e-25 87.7 0.0 9.1e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGO22517.1 - 6e-11 42.7 0.0 1.8e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 YAcAr PF10686.9 EGO22517.1 - 0.072 13.1 0.0 0.74 9.8 0.0 2.3 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Mito_carr PF00153.27 EGO22518.1 - 9e-08 31.9 0.0 0.059 13.3 0.0 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein Uma2 PF05685.12 EGO22519.1 - 0.15 11.6 0.1 0.39 10.2 0.1 1.8 1 1 0 1 1 1 0 Putative restriction endonuclease Reoviridae_Vp9 PF08978.10 EGO22520.1 - 0.036 13.2 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 TPR_1 PF00515.28 EGO22521.1 - 3.5e-29 99.4 0.0 0.0015 18.3 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGO22521.1 - 1.5e-25 87.2 4.4 0.0095 16.0 0.3 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 EGO22521.1 - 4e-21 74.9 0.3 1.5e-20 73.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.6 EGO22521.1 - 7.5e-16 58.2 9.0 0.00065 19.9 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGO22521.1 - 1.1e-13 51.1 6.9 1.1e-05 25.4 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO22521.1 - 1e-11 45.3 11.9 0.016 15.8 0.8 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO22521.1 - 2.1e-11 43.3 0.4 0.086 12.5 0.0 5.8 5 2 1 6 6 6 3 TPR repeat TPR_19 PF14559.6 EGO22521.1 - 7.9e-09 35.9 7.5 0.031 14.8 0.1 5.7 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO22521.1 - 2.3e-07 30.5 0.9 22 5.6 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO22521.1 - 5.2e-07 29.9 12.3 0.54 11.2 0.1 6.7 5 3 3 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO22521.1 - 4.4e-06 26.8 2.0 0.46 10.7 0.7 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGO22521.1 - 0.0002 21.4 0.3 0.25 11.4 0.0 3.9 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EGO22521.1 - 0.00029 21.0 2.3 11 6.6 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO22521.1 - 0.00045 20.1 0.9 32 4.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGO22521.1 - 0.00058 19.2 0.3 0.61 9.6 0.0 4.0 4 0 0 4 4 4 1 SHNi-TPR TPR_MalT PF17874.1 EGO22521.1 - 0.04 13.3 2.9 3.2 7.0 0.0 3.6 1 1 0 2 2 2 0 MalT-like TPR region TPR_6 PF13174.6 EGO22521.1 - 0.04 14.5 3.3 0.75 10.6 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGO22521.1 - 0.23 11.4 9.6 34 4.5 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO22521.1 - 0.28 11.3 1.8 2.5 8.3 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ABC_tran_CTD PF16326.5 EGO22521.1 - 0.97 9.7 4.5 1 9.6 0.2 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain WD40 PF00400.32 EGO22522.1 - 6.2e-35 118.6 22.8 1.2e-06 29.1 0.8 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EGO22522.1 - 5.8e-14 51.7 1.0 5.8e-14 51.7 1.0 2.6 3 0 0 3 3 3 1 F-box-like ANAPC4_WD40 PF12894.7 EGO22522.1 - 3.5e-12 46.5 2.5 0.0031 17.8 0.0 6.1 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EGO22522.1 - 1.1e-07 31.5 0.9 2.8e-07 30.2 0.9 1.8 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EGO22522.1 - 1.1e-06 28.3 0.0 0.033 13.5 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 EGO22522.1 - 0.00012 20.9 5.3 3.8 6.1 0.1 4.5 2 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box_5 PF18511.1 EGO22522.1 - 0.0013 18.2 0.0 0.0046 16.5 0.0 1.9 2 0 0 2 2 2 1 F-box PQQ_3 PF13570.6 EGO22522.1 - 0.61 10.6 4.0 32 5.2 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain DUF3613 PF12266.8 EGO22523.1 - 0.064 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) O-FucT PF10250.9 EGO22524.1 - 6.2e-10 39.3 0.9 0.0011 18.8 0.0 3.1 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase RNase_P_pop3 PF08228.11 EGO22524.1 - 0.021 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 RNase P subunit Pop3 Cu-oxidase PF00394.22 EGO22525.1 - 2e-46 158.0 0.0 2.1e-42 144.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO22525.1 - 1.3e-41 141.5 5.8 3.8e-39 133.6 0.1 4.2 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO22525.1 - 5.1e-39 133.0 1.1 5.2e-38 129.7 0.4 2.7 3 0 0 3 3 3 1 Multicopper oxidase DUF4605 PF15378.6 EGO22526.1 - 0.15 11.9 1.0 0.25 11.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) SRF-TF PF00319.18 EGO22527.1 - 1.8e-21 75.4 0.6 2.7e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GET2 PF08690.10 EGO22527.1 - 1.1 8.8 4.0 1.8 8.2 4.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 dCMP_cyt_deam_1 PF00383.23 EGO22531.1 - 2e-16 59.7 0.0 2.4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGO22531.1 - 1.7e-12 47.7 0.6 9.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGO22531.1 - 0.0026 17.4 3.0 0.051 13.2 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ADH_N PF08240.12 EGO22531.1 - 0.02 14.8 0.1 0.025 14.5 0.1 1.1 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain XOO_2897-deam PF14440.6 EGO22531.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ PF00226.31 EGO22532.1 - 2.1e-09 37.4 0.0 4.5e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 DnaJ domain DDE_Tnp_1 PF01609.21 EGO22533.1 - 0.00022 20.9 0.7 0.00062 19.5 0.1 1.9 2 0 0 2 2 2 1 Transposase DDE domain DUF4674 PF15719.5 EGO22533.1 - 0.052 13.6 3.0 0.091 12.8 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Arabino_trans_N PF17689.1 EGO22533.1 - 0.086 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain GLTP PF08718.11 EGO22534.1 - 8.3e-41 139.7 0.0 1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF4451 PF14616.6 EGO22535.1 - 2.2e-07 31.1 2.8 0.47 10.7 0.0 3.7 2 1 0 3 3 3 3 Domain of unknown function (DUF4451) PHD PF00628.29 EGO22535.1 - 0.75 9.7 4.6 63 3.6 0.0 4.1 4 0 0 4 4 4 0 PHD-finger Fungal_trans PF04082.18 EGO22536.1 - 1.3e-22 80.1 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Questin_oxidase PF14027.6 EGO22537.1 - 4.8e-74 249.9 0.0 1.6e-72 244.9 0.0 2.0 1 1 0 1 1 1 1 Questin oxidase-like Cu-oxidase PF00394.22 EGO22539.1 - 4.3e-52 176.4 0.9 2.3e-48 164.3 0.0 3.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO22539.1 - 1.2e-39 135.0 4.8 1.1e-36 125.4 0.9 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO22539.1 - 1.2e-35 122.2 10.8 1.7e-34 118.5 0.4 3.7 3 1 0 3 3 3 1 Multicopper oxidase Self-incomp_S1 PF05938.11 EGO22539.1 - 0.083 13.4 0.1 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 Peptidase_M28 PF04389.17 EGO22540.1 - 1.9e-27 96.3 0.1 3.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGO22540.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 RRM_1 PF00076.22 EGO22541.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plavaka PF18759.1 EGO22542.1 - 2.3e-38 132.3 0.1 4.3e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase Smg4_UPF3 PF03467.15 EGO22542.1 - 0.19 11.7 5.9 0.34 10.9 5.9 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family Calpain_u2 PF16648.5 EGO22544.1 - 0.33 11.5 4.1 0.15 12.6 0.7 2.2 2 0 0 2 2 2 0 Unstructured region on Calpain-3 VPS28 PF03997.12 EGO22545.1 - 6e-70 234.8 0.0 6.9e-70 234.6 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DnaJ_CXXCXGXG PF00684.19 EGO22546.1 - 0.04 14.3 6.4 2.1 8.8 1.5 2.5 2 0 0 2 2 2 0 DnaJ central domain Anti-TRAP PF15777.5 EGO22546.1 - 9.5 6.3 7.8 4.1 7.4 1.4 2.6 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PhzC-PhzF PF02567.16 EGO22548.1 - 4.7e-42 144.4 0.0 5.5e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Guanylate_kin PF00625.21 EGO22548.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase Methyltransf_15 PF09445.10 EGO22550.1 - 2.2e-36 124.9 0.0 1.9e-27 95.9 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EGO22550.1 - 4.3e-07 30.5 0.0 8.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGO22550.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EGO22550.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EGO22550.1 - 0.00026 20.8 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO22550.1 - 0.00044 20.8 0.0 0.00079 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGO22550.1 - 0.0093 15.7 0.0 0.096 12.4 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGO22550.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGO22550.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EGO22550.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RCC1 PF00415.18 EGO22553.1 - 2.3e-44 149.8 12.7 2.2e-14 53.8 0.1 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO22553.1 - 2.4e-22 78.2 24.4 1.7e-07 30.8 0.5 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 EGO22553.1 - 2.4e-12 46.5 5.8 2.4e-12 46.5 5.8 2.4 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 EGO22553.1 - 0.92 9.5 11.6 0.044 13.7 5.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 EGO22553.1 - 4 7.6 8.3 27 5.0 8.3 2.5 1 1 0 1 1 1 0 PHD-finger SQS_PSY PF00494.19 EGO22554.1 - 1.5e-36 126.3 0.0 1.9e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Transgly PF00912.22 EGO22555.1 - 0.016 14.7 0.3 0.016 14.6 0.3 1.1 1 0 0 1 1 1 0 Transglycosylase VWA_2 PF13519.6 EGO22555.1 - 0.025 15.2 0.2 0.03 15.0 0.2 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain BAR_3 PF16746.5 EGO22555.1 - 0.044 13.5 0.2 0.047 13.4 0.2 1.0 1 0 0 1 1 1 0 BAR domain of APPL family SSF PF00474.17 EGO22556.1 - 3.9e-15 55.6 29.0 7.9e-15 54.6 29.0 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DAO PF01266.24 EGO22558.1 - 2.8e-40 139.0 1.8 3.3e-40 138.7 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO22558.1 - 0.0006 20.0 0.4 0.0027 17.9 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO22558.1 - 0.0037 17.3 0.2 0.028 14.4 0.3 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EGO22558.1 - 0.0083 15.4 0.2 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGO22558.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_2 PF07724.14 EGO22559.1 - 1e-47 162.4 0.0 1.4e-44 152.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGO22559.1 - 9.4e-33 112.3 4.9 2.6e-32 110.8 0.2 2.5 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGO22559.1 - 2.7e-20 72.2 6.9 3e-20 72.1 0.3 3.0 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGO22559.1 - 1.5e-19 70.8 0.1 2.1e-10 41.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO22559.1 - 4.3e-18 65.6 0.0 1.2e-11 44.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO22559.1 - 2.3e-09 37.9 8.2 8.6e-05 23.0 0.1 4.8 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 EGO22559.1 - 8.4e-08 32.6 6.0 0.0016 18.7 0.0 4.6 5 3 1 6 6 2 2 AAA domain Sigma54_activat PF00158.26 EGO22559.1 - 8.8e-08 32.0 0.0 2.8e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGO22559.1 - 1.4e-06 28.1 0.1 0.23 11.2 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 EGO22559.1 - 3.4e-06 27.6 0.1 0.17 12.4 0.1 3.1 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGO22559.1 - 7.8e-06 25.4 0.1 0.26 10.6 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGO22559.1 - 1e-05 25.3 0.0 0.011 15.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGO22559.1 - 1.1e-05 25.1 0.0 0.029 13.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EGO22559.1 - 1.2e-05 25.4 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EGO22559.1 - 3e-05 23.8 0.3 0.63 9.8 0.0 3.4 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EGO22559.1 - 8e-05 23.2 0.9 0.089 13.3 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 EGO22559.1 - 0.0001 22.6 0.4 0.39 10.9 0.0 3.6 3 1 1 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 EGO22559.1 - 0.00045 20.2 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 EGO22559.1 - 0.00045 20.4 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EGO22559.1 - 0.00053 20.3 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 EGO22559.1 - 0.0013 18.7 7.2 0.27 11.1 0.0 4.3 3 2 2 5 5 5 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EGO22559.1 - 0.0084 16.3 1.0 5.1 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EGO22559.1 - 0.0086 16.0 0.0 0.95 9.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 EGO22559.1 - 0.0088 16.0 0.0 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGO22559.1 - 0.011 15.5 0.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EGO22559.1 - 0.014 15.8 0.1 0.4 11.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGO22559.1 - 0.016 15.1 0.0 7.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein DNA_pol3_delta2 PF13177.6 EGO22559.1 - 0.016 15.0 0.0 0.16 11.7 0.0 2.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit FapA PF03961.13 EGO22559.1 - 0.023 13.3 0.9 0.046 12.3 0.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Zeta_toxin PF06414.12 EGO22559.1 - 0.025 13.9 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin HAUS2 PF15003.6 EGO22559.1 - 0.032 14.0 2.1 0.06 13.1 2.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 AAA_3 PF07726.11 EGO22559.1 - 0.033 14.0 0.0 21 5.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGO22559.1 - 0.035 14.1 0.2 8.8 6.3 0.0 3.4 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit EcoEI_R_C PF08463.10 EGO22559.1 - 0.037 14.2 4.4 0.092 12.9 4.4 1.7 1 0 0 1 1 1 0 EcoEI R protein C-terminal AAA_25 PF13481.6 EGO22559.1 - 0.037 13.6 0.0 1.2 8.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EGO22559.1 - 0.039 13.7 2.8 1.1 9.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_21 PF13304.6 EGO22559.1 - 0.041 13.7 3.4 4.7 6.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGO22559.1 - 0.061 12.4 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EGO22559.1 - 0.062 13.2 0.2 8.3 6.3 0.0 3.5 4 0 0 4 4 3 0 NTPase SRP54 PF00448.22 EGO22559.1 - 0.063 12.9 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 EGO22559.1 - 0.18 11.6 3.3 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Spc42p PF11544.8 EGO22559.1 - 0.51 10.4 3.8 1.3 9.1 3.8 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p AAA_23 PF13476.6 EGO22559.1 - 0.57 10.7 21.4 1.4 9.3 0.0 3.8 3 1 0 3 3 2 0 AAA domain UPF0242 PF06785.11 EGO22559.1 - 2.4 8.2 9.5 4.5 7.3 9.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5401 PF17380.2 EGO22559.1 - 6.3 4.7 13.6 9 4.2 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Atg14 PF10186.9 EGO22559.1 - 8.7 5.3 7.5 14 4.6 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RCC1_2 PF13540.6 EGO22561.1 - 4.7e-10 39.0 0.5 3.9e-09 36.1 0.1 2.1 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGO22561.1 - 1e-06 29.2 1.6 0.014 16.0 0.9 2.5 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat FAD_binding_3 PF01494.19 EGO22562.1 - 7.1e-78 262.3 0.0 9.4e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO22562.1 - 2.6e-35 121.9 0.0 6.3e-35 120.7 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EGO22562.1 - 1.2e-06 28.0 0.0 3.4e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO22562.1 - 1.7e-06 28.2 0.1 3.7e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO22562.1 - 2.2e-06 27.5 0.2 2.9e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO22562.1 - 3.7e-06 25.9 0.1 5.5e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGO22562.1 - 6.1e-06 25.6 0.1 1.1e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGO22562.1 - 0.0001 22.8 0.0 0.00051 20.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO22562.1 - 0.00033 20.2 0.1 0.00051 19.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO22562.1 - 0.00037 19.9 0.1 0.00057 19.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO22562.1 - 0.00073 18.8 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGO22562.1 - 0.0015 17.7 0.2 0.033 13.3 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EGO22562.1 - 0.0038 17.7 0.0 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EGO22562.1 - 0.0044 16.3 0.8 0.0064 15.8 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGO22562.1 - 0.023 13.8 0.2 0.052 12.6 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 EGO22562.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGO22562.1 - 0.034 14.0 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EGO22562.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EGO22562.1 - 0.1 11.8 0.0 0.71 9.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EGO22562.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.10 EGO22562.1 - 0.18 10.8 0.0 0.85 8.6 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase AdoHcyase_NAD PF00670.21 EGO22562.1 - 0.18 11.8 0.1 0.34 11.0 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1899 PF08953.11 EGO22563.1 - 7.4e-25 86.6 0.1 1.5e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EGO22563.1 - 4.1e-19 68.6 4.7 9.8e-07 29.4 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_4 PF16300.5 EGO22563.1 - 5e-18 64.7 0.3 1.2e-17 63.5 0.3 1.7 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 EGO22563.1 - 2.1e-05 24.7 0.0 0.034 14.4 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO22563.1 - 0.034 13.1 0.1 1.3 8.0 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APC_N_CC PF16689.5 EGO22563.1 - 0.31 11.1 1.1 0.53 10.4 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain GCV_T PF01571.21 EGO22564.1 - 1.9e-83 279.8 0.0 2.3e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGO22564.1 - 7.5e-22 77.0 0.1 2e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain ESCRT-II PF05871.12 EGO22565.1 - 2.4e-36 125.1 0.1 9.7e-36 123.1 0.1 1.7 2 0 0 2 2 2 1 ESCRT-II complex subunit Glyco_hydro_35 PF01301.19 EGO22566.1 - 1.4e-68 231.9 3.1 1.7e-67 228.3 3.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EGO22566.1 - 2.3e-43 148.1 4.3 5.5e-43 146.9 4.3 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EGO22566.1 - 1.3e-39 135.3 1.1 8.6e-20 71.4 0.8 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EGO22566.1 - 6.3e-19 67.3 0.0 1.9e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EGO22566.1 - 0.0011 18.4 0.3 0.0032 16.9 0.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 EGO22569.1 - 1.8e-24 86.6 0.0 3.3e-11 43.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22569.1 - 1.3e-08 34.5 0.0 0.011 15.0 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EGO22569.1 - 0.00089 18.7 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO22569.1 - 0.0044 16.4 0.1 1.2 8.4 0.0 2.7 4 0 0 4 4 4 2 Kinase-like RIO1 PF01163.22 EGO22569.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Amdo_NSP PF12475.8 EGO22570.1 - 0.042 13.9 0.1 0.098 12.8 0.1 1.6 1 0 0 1 1 1 0 Amdovirus non-structural protein DDE_Tnp_4 PF13359.6 EGO22573.1 - 9.1e-20 70.9 0.3 1.3e-18 67.2 0.3 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO22573.1 - 4.4e-06 26.5 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Ytp1 PF10355.9 EGO22574.1 - 6.3e-35 120.7 18.8 6.9e-33 114.0 18.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) cEGF PF12662.7 EGO22574.1 - 0.13 12.2 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like Retrotrans_gag PF03732.17 EGO22576.1 - 1.7e-06 28.2 1.9 1.7e-06 28.2 1.9 3.5 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EGO22576.1 - 4.9e-05 23.9 0.0 0.00037 21.1 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO22576.1 - 0.00035 21.1 0.2 0.0023 18.5 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Mucin_bdg PF03272.13 EGO22577.1 - 0.002 18.1 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Putative mucin or carbohydrate-binding module BTB PF00651.31 EGO22579.1 - 7.2e-07 29.4 0.1 1.7e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EGO22580.1 - 7.7e-11 42.2 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain NMO PF03060.15 EGO22582.1 - 4.1e-49 167.7 1.4 5.4e-49 167.4 1.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO22582.1 - 5.6e-07 28.9 0.0 1.7e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO22582.1 - 0.021 13.9 3.9 0.033 13.2 3.9 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase HAMP PF00672.25 EGO22583.1 - 0.018 15.4 0.3 1.5 9.3 0.0 3.1 2 0 0 2 2 2 0 HAMP domain TSC22 PF01166.18 EGO22583.1 - 0.07 13.4 15.0 2.9 8.3 0.0 4.8 3 2 2 5 5 5 0 TSC-22/dip/bun family Fib_alpha PF08702.10 EGO22583.1 - 0.077 13.2 23.6 1.3 9.2 0.4 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EGO22583.1 - 0.15 12.5 41.0 0.079 13.4 21.9 2.9 2 1 1 3 3 3 0 Fez1 GAS PF13851.6 EGO22583.1 - 0.5 9.7 40.0 0.21 10.9 12.4 3.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGO22583.1 - 0.55 9.1 39.0 0.79 8.5 13.2 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Taxilin PF09728.9 EGO22583.1 - 0.68 9.1 37.8 4.1 6.5 7.9 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF948 PF06103.11 EGO22583.1 - 1.5 9.2 13.0 3 8.1 0.1 4.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 EGO22583.1 - 1.7 8.1 36.4 0.21 11.2 31.9 1.6 2 0 0 2 2 2 0 Intermediate filament protein TACC_C PF05010.14 EGO22583.1 - 3 7.6 32.7 0.027 14.2 14.5 3.0 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YabA PF06156.13 EGO22583.1 - 4.8 7.9 28.7 5.5 7.7 0.5 4.7 2 1 1 4 4 4 0 Initiation control protein YabA MbeD_MobD PF04899.12 EGO22583.1 - 5.5 7.2 9.8 6.4 7.0 0.7 3.3 2 1 0 3 3 3 0 MbeD/MobD like HALZ PF02183.18 EGO22583.1 - 6.5 7.1 12.0 5 7.4 0.1 4.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF1515 PF07439.11 EGO22583.1 - 7.7 6.6 15.5 7.1 6.7 3.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) ATG16 PF08614.11 EGO22583.1 - 8.4 6.6 42.0 1.9 8.7 11.0 4.0 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 EGO22584.1 - 9.1e-10 38.5 8.3 1.8e-09 37.6 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGO22584.1 - 8.7e-09 35.1 7.0 1.5e-08 34.3 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO22584.1 - 3.1e-08 33.8 7.6 5.9e-08 32.9 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO22584.1 - 7.3e-08 32.1 9.8 1.7e-07 31.0 9.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO22584.1 - 2.6e-07 30.4 8.8 4.7e-07 29.6 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO22584.1 - 2.6e-07 30.5 4.3 2.6e-07 30.5 4.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO22584.1 - 3.9e-06 26.7 7.0 7.5e-06 25.8 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO22584.1 - 4.8e-05 23.1 8.6 0.0001 22.1 8.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGO22584.1 - 0.042 13.7 2.7 0.095 12.5 2.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.6 EGO22584.1 - 0.043 13.6 1.7 0.072 12.9 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_5 PF17121.5 EGO22584.1 - 0.051 13.5 3.5 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HAUS-augmin3 PF14932.6 EGO22584.1 - 0.096 12.2 2.4 0.13 11.8 2.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 zf-RING_6 PF14835.6 EGO22584.1 - 0.18 11.7 3.7 0.48 10.3 3.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TMPIT PF07851.13 EGO22584.1 - 0.57 9.4 4.6 0.73 9.0 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-RING_11 PF17123.5 EGO22584.1 - 0.65 9.8 6.6 1.7 8.5 6.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger BTB PF00651.31 EGO22585.1 - 2.4e-09 37.4 0.0 5.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGO22586.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4407 PF14362.6 EGO22588.1 - 0.0087 15.5 29.0 0.39 10.0 0.0 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4407) ZapB PF06005.12 EGO22588.1 - 0.011 16.1 1.9 0.011 16.1 1.9 5.9 3 2 1 4 4 3 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EGO22588.1 - 0.023 14.8 4.3 0.023 14.8 4.3 4.7 2 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EGO22588.1 - 0.029 13.2 38.6 0.024 13.5 18.1 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 EGO22588.1 - 0.043 13.8 29.0 0.21 11.6 0.4 3.8 2 1 0 3 3 3 0 Laminin Domain II Fez1 PF06818.15 EGO22588.1 - 0.31 11.5 36.4 3.5 8.0 15.8 3.2 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 EGO22588.1 - 0.43 10.8 47.4 4.3 7.5 3.7 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) PGA_cap PF09587.10 EGO22588.1 - 0.44 9.9 0.0 0.44 9.9 0.0 2.3 2 1 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Filament PF00038.21 EGO22588.1 - 0.49 9.9 39.9 0.075 12.6 2.5 4.1 2 1 2 4 4 4 0 Intermediate filament protein APG6_N PF17675.1 EGO22588.1 - 0.55 10.7 49.4 0.13 12.8 17.8 4.6 2 2 2 4 4 4 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 EGO22588.1 - 0.9 8.3 41.6 0.45 9.3 17.0 3.0 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 EGO22588.1 - 1.3 7.1 32.6 0.37 8.9 26.0 2.5 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil GAS PF13851.6 EGO22588.1 - 1.5 8.2 38.0 0.61 9.4 19.4 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding YojJ PF10372.9 EGO22588.1 - 1.5 9.0 0.0 1.5 9.0 0.0 4.7 4 1 2 6 6 6 0 Bacterial membrane-spanning protein N-terminus DUF4201 PF13870.6 EGO22588.1 - 1.8 8.3 34.2 0.23 11.2 2.6 4.3 2 1 1 4 4 4 0 Domain of unknown function (DUF4201) MscS_porin PF12795.7 EGO22588.1 - 2.6 7.5 47.3 1.2 8.7 3.7 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Sec34 PF04136.15 EGO22588.1 - 3.4 7.5 20.2 2.6 7.9 0.3 4.2 3 1 1 4 4 4 0 Sec34-like family TMF_TATA_bd PF12325.8 EGO22588.1 - 6.1 7.1 38.7 2.8 8.2 1.7 4.5 2 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 EGO22588.1 - 6.8 6.9 41.4 0.16 12.2 2.7 4.1 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 CDP-OH_P_transf PF01066.21 EGO22589.1 - 2.9e-14 53.6 1.3 2.9e-14 53.6 1.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase gag-asp_proteas PF13975.6 EGO22590.1 - 0.00067 20.2 0.0 0.0056 17.2 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO22590.1 - 0.011 15.5 0.1 0.93 9.3 0.0 2.0 1 1 1 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO22590.1 - 0.029 15.0 0.0 0.038 14.6 0.0 1.3 1 1 0 1 1 1 0 Aspartyl protease BUD22 PF09073.10 EGO22591.1 - 0.012 15.0 8.7 0.018 14.4 8.7 1.3 1 0 0 1 1 1 0 BUD22 DUF2040 PF09745.9 EGO22591.1 - 0.028 14.5 6.6 0.028 14.5 6.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) SR-25 PF10500.9 EGO22591.1 - 0.3 10.7 12.3 0.52 9.9 12.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGO22591.1 - 1.3 7.2 9.7 1.9 6.7 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EGO22591.1 - 1.6 9.2 8.9 3.8 8.0 8.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IMUP PF15761.5 EGO22591.1 - 1.6 9.5 12.7 4.3 8.1 12.7 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein YL1 PF05764.13 EGO22591.1 - 1.7 8.7 18.5 1.2 9.3 17.1 1.3 1 1 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 EGO22591.1 - 2 7.4 9.4 2.7 6.9 9.2 1.4 1 1 0 1 1 1 0 Pes-10 Anophelin PF10731.9 EGO22591.1 - 2.9 7.8 7.7 6.6 6.7 7.7 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito YqfQ PF14181.6 EGO22591.1 - 5.4 7.2 8.8 9 6.5 8.8 1.3 1 0 0 1 1 1 0 YqfQ-like protein Retrotrans_gag PF03732.17 EGO22592.1 - 0.69 10.2 0.1 0.69 10.2 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein DUF1056 PF06341.11 EGO22593.1 - 8.4 6.8 6.9 1.6 9.1 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) AMP-binding PF00501.28 EGO22594.1 - 1.8e-22 79.5 0.0 6.1e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 EGO22594.1 - 0.0024 16.8 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 GH3 auxin-responsive promoter DUF5336 PF17270.2 EGO22597.1 - 0.15 11.7 1.0 0.24 11.0 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) 4HBT_2 PF13279.6 EGO22598.1 - 1e-12 48.6 0.0 1.5e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EGO22598.1 - 3.9e-08 33.5 0.0 6.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EGO22598.1 - 0.024 13.9 0.0 0.58 9.4 0.1 2.0 2 0 0 2 2 2 0 Acyl-ACP thioesterase CAP_GLY PF01302.25 EGO22599.1 - 1.1e-23 82.9 0.7 2e-23 82.2 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EGO22599.1 - 2.6e-23 82.3 0.0 4.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EGO22599.1 - 0.019 14.7 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family AAA PF00004.29 EGO22600.1 - 4.9e-96 318.2 0.0 1.5e-46 158.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO22600.1 - 1e-25 89.2 7.0 6.8e-13 48.2 0.1 3.3 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 EGO22600.1 - 5.1e-20 71.5 0.2 2.5e-19 69.2 0.3 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGO22600.1 - 5.6e-14 52.2 0.0 1.6e-05 24.7 0.0 3.2 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGO22600.1 - 3.5e-13 50.0 0.0 1.5e-07 31.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGO22600.1 - 9.7e-12 45.2 0.0 5.3e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EGO22600.1 - 2.9e-11 43.0 0.0 6.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EGO22600.1 - 5.3e-11 42.7 0.4 3.3e-05 23.9 0.1 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO22600.1 - 2.4e-10 41.1 0.1 0.0014 19.0 0.0 4.4 3 2 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 EGO22600.1 - 2.9e-09 36.6 0.1 0.0018 17.5 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EGO22600.1 - 6.7e-09 36.1 0.3 0.053 13.8 0.0 4.1 3 2 0 3 3 2 2 AAA domain Vps4_C PF09336.10 EGO22600.1 - 5.3e-08 32.7 0.3 2.9e-06 27.2 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EGO22600.1 - 3.8e-07 30.7 0.0 0.017 15.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGO22600.1 - 4.1e-07 29.6 0.3 0.028 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGO22600.1 - 4.8e-07 29.7 0.0 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EGO22600.1 - 1.6e-06 28.4 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGO22600.1 - 2.7e-06 27.4 0.0 0.024 14.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EGO22600.1 - 3.3e-06 26.7 0.0 0.016 14.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 EGO22600.1 - 3.4e-06 26.6 0.2 0.92 8.8 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 EGO22600.1 - 7.7e-06 25.6 0.5 0.87 9.1 0.0 3.5 2 1 1 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 EGO22600.1 - 1.2e-05 24.6 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EGO22600.1 - 1.7e-05 25.1 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EGO22600.1 - 2.9e-05 23.8 0.0 0.46 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EGO22600.1 - 4e-05 24.1 0.0 0.23 12.0 0.0 3.5 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 EGO22600.1 - 4.4e-05 23.3 0.1 0.44 10.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 EGO22600.1 - 0.0001 22.2 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 EGO22600.1 - 0.00011 22.7 0.3 0.91 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 EGO22600.1 - 0.00012 21.6 0.3 0.5 9.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 EGO22600.1 - 0.00014 21.1 0.0 0.037 13.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EGO22600.1 - 0.00026 20.9 1.4 0.95 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 EGO22600.1 - 0.00029 20.7 0.0 0.82 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGO22600.1 - 0.00033 20.7 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EGO22600.1 - 0.00034 20.6 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EGO22600.1 - 0.00082 19.2 0.0 0.28 10.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGO22600.1 - 0.001 18.4 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UFD1 PF03152.14 EGO22600.1 - 0.0014 18.1 0.0 0.0034 16.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ATPase_2 PF01637.18 EGO22600.1 - 0.0021 18.0 0.2 4.9 7.0 0.0 3.6 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGO22600.1 - 0.0028 17.4 0.4 2.6 7.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 EGO22600.1 - 0.0038 17.3 0.0 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGO22600.1 - 0.0057 15.9 0.0 3.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 EGO22600.1 - 0.0064 16.4 0.1 1.5 8.7 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 EGO22600.1 - 0.0065 16.8 1.9 4.4 7.6 0.0 3.6 3 1 0 4 4 3 0 AAA domain T2SSE PF00437.20 EGO22600.1 - 0.011 14.8 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 EGO22600.1 - 0.013 14.7 0.0 0.73 9.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 EGO22600.1 - 0.038 13.4 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.15 EGO22600.1 - 0.038 13.9 0.4 6.5 6.6 0.0 3.3 3 0 0 3 3 3 0 NTPase KAP_NTPase PF07693.14 EGO22600.1 - 0.042 13.1 0.0 0.5 9.6 0.0 2.4 2 1 1 3 3 3 0 KAP family P-loop domain Cytidylate_kin PF02224.18 EGO22600.1 - 0.047 13.4 0.0 7.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Molydop_binding PF01568.21 EGO22600.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Hydin_ADK PF17213.3 EGO22600.1 - 0.47 10.7 4.4 39 4.4 0.0 4.2 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain DAGAT PF03982.13 EGO22601.1 - 1.8e-98 329.1 0.0 2.4e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Lipase_3 PF01764.25 EGO22602.1 - 9.7e-22 77.4 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGO22602.1 - 0.034 13.4 0.1 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO22602.1 - 0.095 13.3 1.4 0.11 13.1 0.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cellulase PF00150.18 EGO22603.1 - 7.9e-13 48.5 2.4 2.6e-12 46.8 2.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ytp1 PF10355.9 EGO22604.1 - 3.9e-50 170.6 16.3 3.9e-50 170.6 16.3 2.9 3 2 0 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGO22604.1 - 7.2e-26 90.0 0.6 7.2e-26 90.0 0.6 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 EGO22604.1 - 8.2e-05 22.8 4.8 8.2e-05 22.8 4.8 3.4 3 2 1 4 4 4 1 Eukaryotic cytochrome b561 MMgT PF10270.9 EGO22604.1 - 0.017 15.5 0.1 0.045 14.1 0.1 1.8 1 0 0 1 1 1 0 Membrane magnesium transporter rhaM PF05336.13 EGO22605.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 L-rhamnose mutarotase Ytp1 PF10355.9 EGO22606.1 - 1.4e-51 175.4 14.2 1.4e-51 175.4 14.2 2.9 3 1 0 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGO22606.1 - 7.9e-26 89.9 0.6 7.9e-26 89.9 0.6 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 EGO22606.1 - 7.4e-05 22.9 4.6 7.4e-05 22.9 4.6 3.7 3 2 1 4 4 4 1 Eukaryotic cytochrome b561 MMgT PF10270.9 EGO22606.1 - 0.015 15.6 0.1 0.049 14.0 0.1 1.9 1 0 0 1 1 1 0 Membrane magnesium transporter NAD_binding_10 PF13460.6 EGO22607.1 - 1.5e-06 28.2 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGO22607.1 - 0.093 13.2 0.0 0.22 11.9 0.0 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGO22608.1 - 1e-06 28.8 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO22608.1 - 0.00021 20.9 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO22608.1 - 0.00071 20.0 0.0 0.0018 18.7 0.0 1.7 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RNA_pol_3_Rpc31 PF11705.8 EGO22609.1 - 0.018 15.3 3.4 0.042 14.1 3.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GAS PF13851.6 EGO22609.1 - 0.029 13.7 2.2 0.05 12.9 2.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 EGO22609.1 - 0.27 11.1 2.6 0.62 9.9 2.6 1.6 1 0 0 1 1 1 0 Sec34-like family Spc24 PF08286.11 EGO22609.1 - 3.2 8.0 6.1 26 5.1 0.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UBX PF00789.20 EGO22611.1 - 4.4e-11 42.8 0.0 1.1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 EGO22611.1 - 7.5e-06 25.7 0.1 2.9e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 UBA/TS-N domain Rtf2 PF04641.12 EGO22611.1 - 0.016 14.6 16.3 0.024 14.0 16.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_2 PF12756.7 EGO22611.1 - 0.23 11.8 2.6 0.24 11.7 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CompInhib_SCIN PF11546.8 EGO22611.1 - 0.42 10.7 13.5 0.029 14.4 5.3 2.3 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN zf-C2H2 PF00096.26 EGO22613.1 - 0.0044 17.4 0.7 0.0044 17.4 0.7 2.4 2 1 0 2 2 2 1 Zinc finger, C2H2 type Pkinase PF00069.25 EGO22614.1 - 8.8e-06 25.3 0.1 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO22614.1 - 0.00043 20.3 0.2 0.00068 19.6 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO22614.1 - 0.022 14.1 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_H2_suC PF08615.11 EGO22616.1 - 4.1e-19 69.2 0.0 5.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ashwin PF15323.6 EGO22616.1 - 0.043 13.8 1.7 0.074 13.1 1.7 1.3 1 0 0 1 1 1 0 Developmental protein COesterase PF00135.28 EGO22617.1 - 1.7e-54 185.6 0.0 3.4e-54 184.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO22617.1 - 9e-08 32.2 0.3 2.7e-07 30.7 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.21 EGO22618.1 - 1.7e-15 57.0 0.0 3.2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EGO22618.1 - 1.1e-05 25.2 0.1 2.6e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EGO22618.1 - 0.045 12.1 0.0 0.062 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) AA_permease_2 PF13520.6 EGO22619.1 - 5.2e-53 180.4 55.9 6.2e-53 180.1 55.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO22619.1 - 5.7e-14 51.6 49.1 5.7e-14 51.6 49.1 1.5 1 1 1 2 2 2 1 Amino acid permease Patatin PF01734.22 EGO22619.1 - 0.035 14.3 0.4 0.057 13.6 0.4 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase DUF3341 PF11821.8 EGO22619.1 - 0.73 9.5 6.8 0.28 10.8 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Arginase PF00491.21 EGO22620.1 - 9.9e-88 294.3 0.0 1.3e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family MatE PF01554.18 EGO22621.1 - 2.1e-35 121.8 21.5 6.8e-27 94.1 9.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGO22621.1 - 0.00053 20.1 4.9 0.00053 20.1 4.9 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 EGO22621.1 - 0.31 11.1 1.1 0.39 10.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus WLM PF08325.10 EGO22622.1 - 7.2e-43 146.9 0.1 1.2e-42 146.2 0.1 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 EGO22622.1 - 1.1e-10 41.1 0.1 2.3e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 EGO22622.1 - 0.00084 19.2 0.0 0.0035 17.2 0.0 1.9 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EGO22622.1 - 0.005 17.3 0.1 0.014 15.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain DUF45 PF01863.17 EGO22622.1 - 0.032 14.3 0.3 0.096 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Ran_BP1 PF00638.18 EGO22623.1 - 1.4e-06 28.6 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain MAGI_u5 PF16666.5 EGO22625.1 - 5.7 7.1 11.4 1.8 8.7 0.4 2.8 3 0 0 3 3 3 0 Unstructured region on MAGI DNA_pol_delta_4 PF04081.13 EGO22626.1 - 1.7e-29 102.8 3.1 5.8e-29 101.1 0.1 2.1 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 FAD_binding_3 PF01494.19 EGO22628.1 - 5e-80 269.4 0.0 7.6e-80 268.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO22628.1 - 1.3e-35 122.8 0.0 2.4e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EGO22628.1 - 5e-07 28.8 1.1 7.4e-07 28.2 1.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGO22628.1 - 1.5e-06 27.5 1.9 2.6e-06 26.8 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO22628.1 - 9.2e-06 25.8 1.0 1.7e-05 24.9 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGO22628.1 - 2.8e-05 23.6 0.8 4.9e-05 22.9 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO22628.1 - 3.3e-05 23.3 1.0 5e-05 22.7 0.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO22628.1 - 3.7e-05 23.1 0.1 6.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EGO22628.1 - 3.9e-05 23.4 0.3 0.00012 21.7 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO22628.1 - 7e-05 22.2 0.2 0.00012 21.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EGO22628.1 - 0.00022 21.7 0.1 0.00044 20.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO22628.1 - 0.00023 20.2 0.1 0.00033 19.6 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGO22628.1 - 0.00028 20.2 1.6 0.0005 19.4 0.8 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO22628.1 - 0.00032 19.9 1.1 0.00057 19.1 1.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGO22628.1 - 0.00041 19.5 1.5 0.0014 17.7 1.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 EGO22628.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase TrkA_N PF02254.18 EGO22628.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EGO22628.1 - 0.016 15.1 0.4 0.036 13.9 0.3 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGO22628.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EGO22628.1 - 0.028 14.4 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.6 EGO22628.1 - 0.055 14.0 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 EGO22628.1 - 0.076 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EGO22628.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain APH PF01636.23 EGO22629.1 - 3.4e-07 30.4 0.0 8.6e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGO22629.1 - 0.00057 18.9 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EGO22629.1 - 0.0028 17.0 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase FAD_binding_3 PF01494.19 EGO22631.1 - 1.5e-88 297.4 0.0 2.8e-88 296.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO22631.1 - 7.2e-40 136.7 0.0 1.3e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EGO22631.1 - 1.6e-06 27.1 0.9 2.4e-06 26.5 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO22631.1 - 4.5e-06 26.8 0.1 1.2e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO22631.1 - 7.8e-06 25.2 1.7 1.2e-05 24.6 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO22631.1 - 2.2e-05 24.2 0.2 0.00028 20.6 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO22631.1 - 6.6e-05 22.3 1.3 0.0001 21.7 0.6 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO22631.1 - 0.00051 19.5 0.6 0.00085 18.8 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO22631.1 - 0.00061 20.3 0.1 0.0035 17.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO22631.1 - 0.00073 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EGO22631.1 - 0.00096 18.5 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EGO22631.1 - 0.0011 18.1 1.9 0.0041 16.2 1.2 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 EGO22631.1 - 0.0014 17.8 0.9 0.0025 17.0 0.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGO22631.1 - 0.0023 17.2 0.1 0.0045 16.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGO22631.1 - 0.0048 16.6 0.1 0.0092 15.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGO22631.1 - 0.0054 16.6 0.4 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGO22631.1 - 0.0073 16.6 0.0 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Trp_halogenase PF04820.14 EGO22631.1 - 0.0089 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase SE PF08491.10 EGO22631.1 - 0.017 14.2 0.0 0.057 12.5 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 EGO22631.1 - 0.021 14.8 0.1 0.053 13.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.6 EGO22631.1 - 0.035 14.6 0.0 0.37 11.3 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 EGO22631.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EGO22631.1 - 0.099 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UCH PF00443.29 EGO22632.1 - 1.2e-66 224.8 0.0 1.8e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO22632.1 - 1e-19 71.3 0.0 1e-17 64.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Dynactin_p22 PF07426.11 EGO22632.1 - 0.16 11.8 0.3 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 zf-HC5HC2H_2 PF13832.6 EGO22633.1 - 2e-19 69.8 22.7 9.4e-19 67.6 3.7 4.4 2 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGO22633.1 - 4.5e-14 52.5 1.2 4.5e-14 52.5 1.2 4.9 4 2 1 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.18 EGO22633.1 - 4.8e-13 49.0 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 EGO22633.1 - 2.2e-11 43.5 58.5 1.1e-07 31.6 9.1 6.6 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 EGO22633.1 - 0.0017 17.8 32.6 0.0046 16.5 4.2 5.8 5 0 0 5 5 5 3 PHD-finger C1_1 PF00130.22 EGO22633.1 - 0.0045 16.9 2.0 0.0045 16.9 2.0 5.9 5 2 2 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_2 PF14445.6 EGO22633.1 - 0.011 15.8 0.6 0.011 15.8 0.6 4.3 5 0 0 5 5 3 0 Prokaryotic RING finger family 2 C1_2 PF03107.16 EGO22633.1 - 0.033 14.5 0.4 0.033 14.5 0.4 6.7 5 1 1 6 6 6 0 C1 domain DUF3603 PF12227.8 EGO22633.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) AT_hook PF02178.19 EGO22633.1 - 0.09 12.7 4.6 0.37 10.8 4.6 2.1 1 0 0 1 1 1 0 AT hook motif EcsC PF12787.7 EGO22633.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family HATPase_c PF02518.26 EGO22634.1 - 5.2e-23 81.7 0.0 1.1e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO22634.1 - 2.5e-18 66.3 0.2 2.7e-17 62.9 0.2 2.5 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c_3 PF13589.6 EGO22634.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ran_BP1 PF00638.18 EGO22635.1 - 1.2e-09 38.5 1.2 6e-09 36.2 1.2 2.0 1 1 0 1 1 1 1 RanBP1 domain Ribosomal_L5_C PF00673.21 EGO22636.1 - 9.8e-21 73.8 0.0 1.5e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGO22636.1 - 4.2e-12 46.2 0.1 1.1e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Herpes_env PF01673.18 EGO22638.1 - 0.093 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Herpes_env PF01673.18 EGO22639.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SNF2_N PF00176.23 EGO22640.1 - 3.2e-11 42.5 0.6 6.3e-11 41.6 0.5 1.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGO22640.1 - 0.00051 20.1 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DKNYY PF13644.6 EGO22643.1 - 0.007 17.1 0.8 0.0086 16.9 0.8 1.1 1 0 0 1 1 1 1 DKNYY family DUF4939 PF16297.5 EGO22643.1 - 0.014 15.2 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Plavaka PF18759.1 EGO22647.1 - 2e-19 70.0 0.0 2.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 EGO22647.1 - 0.016 15.6 0.1 0.034 14.6 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO22647.1 - 0.089 13.7 0.1 0.24 12.3 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase_fungal PF17667.1 EGO22648.1 - 4.8e-25 88.2 0.0 1.5e-12 47.0 0.1 2.1 2 0 0 2 2 2 2 Fungal protein kinase zf-C2H2_4 PF13894.6 EGO22649.1 - 0.057 14.3 0.7 0.057 14.3 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO22649.1 - 0.077 13.5 0.8 0.077 13.5 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2407_C PF13373.6 EGO22649.1 - 0.091 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain zf-C2H2_aberr PF17017.5 EGO22649.1 - 0.14 12.3 0.3 0.31 11.2 0.3 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger ADD_ATRX PF17981.1 EGO22649.1 - 0.24 11.3 2.8 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Cysteine Rich ADD domain Plavaka PF18759.1 EGO22650.1 - 1.1e-34 120.1 4.5 5.5e-18 65.3 0.1 2.0 1 1 1 2 2 2 2 Plavaka transposase Sec_GG PF07549.14 EGO22651.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif ANAPC2 PF08672.11 EGO22654.1 - 2.4 8.7 5.9 9.1 6.9 0.2 4.3 4 2 1 5 5 5 0 Anaphase promoting complex (APC) subunit 2 AbbA_antirepres PF14156.6 EGO22656.1 - 0.053 13.4 2.2 0.22 11.5 0.0 2.8 3 0 0 3 3 3 0 Antirepressor AbbA DUF5387 PF17361.2 EGO22657.1 - 0.03 14.0 0.3 0.038 13.7 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5387) TMEM171 PF15471.6 EGO22657.1 - 0.065 12.2 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Catalase PF00199.19 EGO22658.1 - 3.8e-156 520.0 0.1 4.6e-156 519.8 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGO22658.1 - 9.8e-12 44.9 0.0 2.7e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Thioredoxin PF00085.20 EGO22659.1 - 6.8e-22 77.4 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGO22659.1 - 0.00076 19.9 0.1 0.0026 18.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGO22659.1 - 0.0027 17.1 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGO22659.1 - 0.0027 17.6 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EGO22659.1 - 0.0029 17.8 0.0 0.03 14.5 0.1 2.5 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGO22659.1 - 0.0069 16.7 0.0 0.034 14.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EGO22659.1 - 0.032 13.9 0.1 0.35 10.6 0.0 2.3 2 1 1 3 3 3 0 Redoxin Thioredoxin_9 PF14595.6 EGO22659.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin STT3 PF02516.14 EGO22660.1 - 1.5e-145 485.9 37.1 9e-140 466.8 33.2 2.6 2 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit p450 PF00067.22 EGO22661.1 - 4.5e-33 114.7 0.1 8e-33 113.9 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 PRIMA1 PF16101.5 EGO22663.1 - 0.031 14.3 4.2 0.048 13.7 4.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DDE_1 PF03184.19 EGO22665.1 - 4.3e-06 26.5 0.1 1.1e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease PCDO_beta_N PF12391.8 EGO22665.1 - 0.52 10.0 3.5 0.84 9.3 0.0 2.7 3 0 0 3 3 3 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal LOR PF04525.12 EGO22666.1 - 0.038 13.6 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 LURP-one-related LPD23 PF18838.1 EGO22666.1 - 0.18 11.6 1.8 0.37 10.6 1.8 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 Mt_ATP-synt_B PF05405.14 EGO22668.1 - 4.1e-45 153.3 9.9 5.3e-45 153.0 9.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_E_2 PF08112.11 EGO22668.1 - 0.013 15.8 1.0 0.35 11.2 0.6 2.3 2 0 0 2 2 2 0 ATP synthase epsilon subunit Viral_Hsp90 PF03225.14 EGO22668.1 - 0.028 13.0 0.5 0.04 12.4 0.5 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue DUF5623 PF18536.1 EGO22668.1 - 0.063 13.6 2.2 0.093 13.0 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) DUF4004 PF13171.6 EGO22668.1 - 0.075 13.3 5.7 0.11 12.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) HTH_46 PF15977.5 EGO22668.1 - 0.11 12.5 0.0 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding NDUF_B8 PF05821.11 EGO22668.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SLATT_1 PF18181.1 EGO22668.1 - 0.28 11.1 7.7 0.13 12.2 4.9 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Dynamin_M PF01031.20 EGO22669.1 - 6.2e-110 366.9 0.1 1.4e-109 365.8 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGO22669.1 - 3.2e-54 183.5 0.0 5.8e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGO22669.1 - 2e-29 101.6 1.4 3.3e-29 100.9 0.5 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO22669.1 - 0.00012 22.1 0.1 0.00096 19.2 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.8 EGO22669.1 - 0.062 13.5 0.1 0.67 10.1 0.0 2.4 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit ABC_tran PF00005.27 EGO22669.1 - 0.1 13.1 0.1 8.7 6.9 0.0 3.2 3 1 0 3 3 3 0 ABC transporter AIG1 PF04548.16 EGO22669.1 - 0.12 11.6 0.0 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 AIG1 family TipAS PF07739.13 EGO22669.1 - 0.18 12.4 0.1 0.57 10.7 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TetR_C_8 PF14278.6 EGO22669.1 - 0.22 11.7 0.3 0.88 9.7 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region SPX PF03105.19 EGO22669.1 - 5.7 6.8 7.3 11 5.8 7.3 1.4 1 0 0 1 1 1 0 SPX domain SYS1 PF09801.9 EGO22670.1 - 2.4e-27 95.9 7.2 2e-20 73.4 4.4 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network MORN PF02493.20 EGO22670.1 - 0.088 12.7 1.4 0.29 11.1 1.3 1.9 1 1 0 1 1 1 0 MORN repeat DPPIV_N PF00930.21 EGO22671.1 - 6.9e-93 311.2 2.2 8.4e-93 310.9 0.2 1.9 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGO22671.1 - 9.1e-47 159.3 0.8 1.6e-46 158.4 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGO22671.1 - 1.3e-05 24.9 2.5 2.6e-05 23.9 1.6 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGO22671.1 - 2.3e-05 24.2 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO22671.1 - 0.0032 18.1 0.1 0.015 15.9 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EGO22671.1 - 0.029 13.1 0.1 0.16 10.6 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mito_carr PF00153.27 EGO22673.1 - 5.4e-57 189.7 4.3 1.4e-20 73.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_Helicase PF02689.14 EGO22673.1 - 0.12 10.3 0.0 0.13 10.1 0.0 1.1 1 0 0 1 1 1 0 Helicase Tim17 PF02466.19 EGO22673.1 - 0.53 10.7 4.0 3.4 8.1 0.2 3.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 EGO22676.1 - 7.7e-22 77.9 0.0 2e-19 70.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO22676.1 - 7.4e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO22676.1 - 0.0044 17.0 0.2 0.0066 16.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO22676.1 - 0.038 13.6 0.2 0.054 13.1 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CMD PF02627.20 EGO22677.1 - 0.00058 19.9 0.0 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Mito_fiss_Elm1 PF06258.11 EGO22677.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Cofilin_ADF PF00241.20 EGO22678.1 - 3e-24 85.1 0.0 4.2e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.9 EGO22678.1 - 0.19 11.7 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Cu-oxidase PF00394.22 EGO22679.1 - 8.9e-46 155.9 0.0 1.7e-41 142.0 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO22679.1 - 6.8e-38 129.3 2.3 1.4e-35 121.9 0.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO22679.1 - 7.1e-37 126.2 6.2 2.2e-35 121.4 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase PAT1 PF09770.9 EGO22680.1 - 1.6e-108 364.2 43.7 1.1e-107 361.4 43.7 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ribosomal_L28e PF01778.17 EGO22681.1 - 1.6e-37 128.7 1.9 1.6e-37 128.7 1.9 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGO22681.1 - 4.8e-28 97.7 11.8 4.8e-28 97.7 11.8 2.1 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGO22681.1 - 0.0011 18.5 12.8 0.0014 18.0 12.8 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EGO22681.1 - 0.033 13.9 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain RRN3 PF05327.11 EGO22681.1 - 0.13 10.8 9.4 0.23 10.0 9.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EGO22681.1 - 8.9 4.4 17.0 11 4.1 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1604 PF07713.13 EGO22682.1 - 2e-38 130.1 0.7 2e-38 130.1 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGO22682.1 - 3.8e-06 26.7 2.2 2.8e-05 23.9 0.1 2.6 2 0 0 2 2 2 1 G-patch domain SRP-alpha_N PF04086.13 EGO22682.1 - 1.3 8.9 9.8 3.3 7.5 9.8 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Amidase PF01425.21 EGO22683.1 - 1e-110 370.8 0.2 1.9e-110 369.9 0.1 1.5 1 1 0 1 1 1 1 Amidase Mito_carr PF00153.27 EGO22684.1 - 2.9e-62 206.6 2.2 1.3e-22 79.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4218 PF13960.6 EGO22686.1 - 0.00049 19.7 0.1 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) DDE_Tnp_1_2 PF13586.6 EGO22686.1 - 0.19 12.1 0.5 0.45 10.9 0.5 1.6 1 0 0 1 1 1 0 Transposase DDE domain ALMS_repeat PF18727.1 EGO22687.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Alstrom syndrome repeat Retrotrans_gag PF03732.17 EGO22690.1 - 1.9e-07 31.3 6.0 1.9e-07 31.3 0.1 3.0 2 1 1 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO22690.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 EGO22691.1 - 2.2e-06 27.8 1.4 2.2e-06 27.8 1.4 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO22691.1 - 2.3e-05 24.2 5.2 6.1e-05 22.9 5.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO22691.1 - 0.0087 16.0 8.3 0.0087 16.0 8.3 2.3 2 1 0 2 2 2 1 Zinc knuckle Gpi16 PF04113.14 EGO22695.1 - 1.5e-142 475.9 0.1 1.9e-141 472.3 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component F-box-like PF12937.7 EGO22696.1 - 0.0023 17.8 0.1 0.0093 15.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like RIIa PF02197.17 EGO22696.1 - 0.022 14.4 0.2 0.26 11.0 0.0 2.5 3 0 0 3 3 3 0 Regulatory subunit of type II PKA R-subunit HTH_50 PF18024.1 EGO22697.1 - 0.067 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain E3_binding PF02817.17 EGO22697.1 - 0.18 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 e3 binding domain 3-HAO PF06052.12 EGO22698.1 - 8.6e-59 197.5 0.0 9.7e-59 197.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGO22698.1 - 8.9e-06 25.3 0.8 1.2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 EGO22698.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain GFO_IDH_MocA PF01408.22 EGO22701.1 - 8.8e-12 45.9 0.2 5.3e-11 43.4 0.2 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO22701.1 - 0.0095 15.9 0.1 0.065 13.2 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 EGO22701.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding_2 PF13380.6 EGO22701.1 - 0.12 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Mpv17_PMP22 PF04117.12 EGO22702.1 - 8.5e-23 80.4 0.3 1.7e-22 79.4 0.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family adh_short PF00106.25 EGO22703.1 - 8.1e-43 146.1 0.0 1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO22703.1 - 4.3e-31 108.3 0.0 5.4e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO22703.1 - 9.9e-09 35.4 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO22703.1 - 3.7e-07 30.2 0.2 6.9e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO22703.1 - 3.8e-05 23.3 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO22703.1 - 0.0022 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EGO22703.1 - 0.014 15.9 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EGO22703.1 - 0.028 14.0 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EGO22703.1 - 0.085 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Rotamase_3 PF13616.6 EGO22703.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain DDE_1 PF03184.19 EGO22705.1 - 3.9e-16 59.2 0.0 6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EGO22708.1 - 1.6e-05 24.5 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain adh_short PF00106.25 EGO22709.1 - 6e-44 149.8 0.0 7.3e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO22709.1 - 1.8e-31 109.5 0.0 2.3e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO22709.1 - 2e-09 37.6 0.0 3.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO22709.1 - 1.4e-07 31.6 0.2 2.6e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO22709.1 - 2.7e-05 23.8 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO22709.1 - 0.0027 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EGO22709.1 - 0.013 16.0 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EGO22709.1 - 0.02 14.5 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 EGO22709.1 - 0.075 13.3 0.1 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGO22710.1 - 0.00011 22.2 0.1 0.0012 18.8 0.0 2.6 1 1 1 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO22710.1 - 0.00069 18.9 0.1 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EGO22710.1 - 0.012 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EGO22710.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gemini_AC4_5 PF04807.12 EGO22710.1 - 0.23 11.2 0.6 0.42 10.3 0.6 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region BCMA-Tall_bind PF09257.10 EGO22711.1 - 0.15 12.2 0.2 0.38 10.9 0.2 1.6 1 0 0 1 1 1 0 BCMA, TALL-1 binding adh_short_C2 PF13561.6 EGO22712.1 - 5.3e-50 170.2 0.3 6.7e-50 169.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO22712.1 - 1.2e-36 126.0 0.7 1.5e-36 125.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO22712.1 - 5.5e-10 39.4 0.1 8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 EGO22712.1 - 0.003 17.1 0.2 0.0071 15.8 0.2 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiF PF00899.21 EGO22714.1 - 5.9e-72 241.9 0.0 8.5e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EGO22714.1 - 2e-15 57.4 0.6 1.2e-14 54.8 0.6 2.1 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 EGO22714.1 - 8.5e-07 29.5 0.0 2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 EGO22714.1 - 0.0033 17.9 0.0 0.012 16.0 0.0 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding Glyco_hydro_71 PF03659.14 EGO22715.1 - 4.8e-104 348.2 9.2 1.6e-94 316.9 8.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Putative_PNPOx PF01243.20 EGO22716.1 - 2.7e-05 24.3 0.0 0.0025 18.0 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 EGO22716.1 - 5e-05 23.5 0.0 8.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain GST_C_2 PF13410.6 EGO22717.1 - 2.1e-10 40.4 0.1 3.7e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO22717.1 - 7.3e-09 35.9 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO22717.1 - 7.6e-07 29.3 0.0 1.6e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO22717.1 - 4e-06 27.1 0.0 6.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 EGO22717.1 - 2.9e-05 23.9 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C PF00043.25 EGO22717.1 - 0.00014 22.0 0.0 0.00028 21.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO22717.1 - 0.0018 18.6 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGO22717.1 - 0.18 11.6 0.0 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain YqcI_YcgG PF08892.11 EGO22718.1 - 1e-64 218.3 0.0 1.1e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 YqcI/YcgG family Catalase PF00199.19 EGO22719.1 - 2.2e-157 524.1 0.0 2.7e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGO22719.1 - 9.7e-12 44.9 0.0 2.9e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive CPL PF08144.11 EGO22720.1 - 3.8e-35 121.3 0.1 1e-30 107.0 0.0 4.0 4 0 0 4 4 4 2 CPL (NUC119) domain Tape_meas_lam_C PF09718.10 EGO22720.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Protamine_3 PF08188.11 EGO22725.1 - 0.028 14.6 0.2 0.029 14.5 0.2 1.1 1 0 0 1 1 1 0 Spermatozal protamine family Methyltransf_2 PF00891.18 EGO22728.1 - 5.6e-21 74.8 0.0 2.2e-19 69.6 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGO22728.1 - 0.0051 17.5 0.0 0.017 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO22728.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.19 EGO22730.1 - 5.2e-45 154.1 0.0 8e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO22730.1 - 2e-25 90.0 0.0 4.5e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ish1 PF10281.9 EGO22730.1 - 0.066 13.5 0.5 3.3 8.1 0.2 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Sld5 PF05916.11 EGO22732.1 - 5.8e-05 23.5 0.0 8.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 EGO22732.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus ThiF PF00899.21 EGO22733.1 - 6.3e-16 58.5 0.0 1.6e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family SPX PF03105.19 EGO22734.1 - 2.7e-44 152.7 0.1 4.1e-44 152.1 0.1 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EGO22734.1 - 2.7e-08 33.5 6.1 4.4e-08 32.9 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO22734.1 - 3e-07 30.2 7.9 5.5e-07 29.4 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO22734.1 - 9.6e-07 28.9 7.0 1.8e-06 28.0 7.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGO22734.1 - 2.7e-06 27.6 7.5 4.7e-06 26.8 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGO22734.1 - 1.1e-05 25.2 7.2 2e-05 24.3 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGO22734.1 - 4.2e-05 23.4 7.5 8e-05 22.5 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO22734.1 - 0.00015 21.6 8.1 0.00026 20.8 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO22734.1 - 0.00016 21.6 5.6 0.00035 20.5 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGO22734.1 - 0.0004 20.1 2.1 0.00088 19.0 2.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGO22734.1 - 0.0057 16.9 4.6 0.012 15.9 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGO22734.1 - 0.02 14.8 3.1 0.036 13.9 3.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LcrG PF07216.12 EGO22734.1 - 0.031 14.2 0.1 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 LcrG protein zf-RING_10 PF16685.5 EGO22734.1 - 0.035 14.2 4.1 0.065 13.4 4.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGO22734.1 - 0.11 12.5 1.1 0.21 11.7 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PCRF PF03462.18 EGO22735.1 - 1e-49 169.1 0.3 5.4e-49 166.7 0.0 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGO22735.1 - 3.4e-35 120.5 3.1 6.6e-35 119.5 3.1 1.4 1 0 0 1 1 1 1 RF-1 domain DUF2781 PF10914.8 EGO22736.1 - 0.0012 19.3 1.8 0.99 9.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2781) DUF2534 PF10749.9 EGO22736.1 - 0.007 16.5 3.3 0.014 15.5 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2534) UCR_UQCRX_QCR9 PF05365.12 EGO22736.1 - 0.54 10.2 0.2 0.54 10.2 0.2 2.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2207 PF09972.9 EGO22736.1 - 2.4 6.8 3.4 2.8 6.6 3.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.11 EGO22736.1 - 3 7.3 5.8 0.54 9.7 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 EGO22736.1 - 6.5 6.4 7.6 2.6 7.7 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) UBA_4 PF14555.6 EGO22739.1 - 8.8e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGO22739.1 - 1.5e-08 34.7 0.0 3.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF874 PF05917.11 EGO22739.1 - 1.6 7.7 6.3 2.2 7.2 6.3 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4746 PF15928.5 EGO22739.1 - 4.1 6.8 7.0 6.3 6.1 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1682 PF07946.14 EGO22739.1 - 5 6.2 14.3 8.5 5.5 14.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) EF-hand_7 PF13499.6 EGO22740.1 - 7.9e-12 45.5 0.0 9.7e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO22740.1 - 1e-11 43.7 0.2 0.00012 21.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGO22740.1 - 8.7e-11 40.6 0.1 0.00032 20.0 0.0 3.5 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGO22740.1 - 1.4e-06 28.6 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGO22740.1 - 5.6e-05 22.9 0.1 0.0014 18.4 0.1 2.8 2 2 0 2 2 2 1 EF-hand domain pair SapB_1 PF05184.15 EGO22740.1 - 0.034 14.2 0.1 10 6.2 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_11 PF08976.11 EGO22740.1 - 0.1 13.5 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EGO22740.1 - 0.12 11.9 1.5 0.66 9.6 0.2 2.5 2 1 0 2 2 2 0 EF hand DDE_Tnp_IS66_C PF13817.6 EGO22740.1 - 0.12 12.6 0.1 0.41 10.9 0.1 1.8 2 0 0 2 2 2 0 IS66 C-terminal element PQQ_2 PF13360.6 EGO22742.1 - 0.003 17.2 0.1 0.0067 16.0 0.1 1.7 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EGO22742.1 - 0.11 12.8 0.0 1.3 9.3 0.0 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain YL1_C PF08265.11 EGO22743.1 - 1.1e-13 50.7 0.2 1.5e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RSN1_7TM PF02714.15 EGO22744.1 - 1e-80 271.0 24.6 1e-80 271.0 24.6 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGO22744.1 - 2.8e-34 118.9 0.1 4.4e-34 118.2 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGO22744.1 - 3.4e-33 114.6 8.1 3.4e-33 114.6 8.1 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 EGO22744.1 - 0.072 12.9 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LysM PF01476.20 EGO22745.1 - 4.4e-09 36.3 1.2 1.1e-05 25.4 0.1 2.9 2 0 0 2 2 2 2 LysM domain WD40 PF00400.32 EGO22745.1 - 0.0059 17.4 9.5 0.0093 16.8 0.2 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat AA_permease PF00324.21 EGO22746.1 - 0.01 14.5 0.7 0.01 14.5 0.7 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.19 EGO22747.1 - 2.2e-66 224.5 0.0 2.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO22747.1 - 0.031 14.5 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO22747.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGO22747.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EGO22747.1 - 0.12 11.6 0.0 0.39 9.9 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO22747.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CMAS PF02353.20 EGO22748.1 - 1.1e-66 224.9 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO22748.1 - 6.4e-11 42.8 0.0 2.8e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO22748.1 - 2e-10 41.2 0.0 2.6e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO22748.1 - 1.1e-09 38.4 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGO22748.1 - 9.3e-05 22.0 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 EGO22748.1 - 0.00026 21.7 0.0 0.00066 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO22748.1 - 0.0028 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGO22748.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGO22748.1 - 0.035 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGO22748.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGO22748.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) YIF1 PF03878.15 EGO22749.1 - 4.4e-91 304.6 0.4 5.6e-91 304.3 0.4 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EGO22749.1 - 1.2e-06 28.4 1.7 1.9e-06 27.7 1.7 1.3 1 0 0 1 1 1 1 Yip1 domain p450 PF00067.22 EGO22751.1 - 1.5e-61 208.6 0.0 1.5e-60 205.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Nrap_D4 PF17405.2 EGO22752.1 - 1.1e-63 214.5 0.0 2e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 EGO22752.1 - 8.1e-46 156.0 0.1 2.1e-45 154.7 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D2 PF17403.2 EGO22752.1 - 3e-43 147.2 0.0 8.4e-43 145.8 0.0 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 EGO22752.1 - 1.9e-40 138.3 0.0 3.8e-39 134.1 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 EGO22752.1 - 9.4e-38 129.6 0.3 1.5e-37 129.0 0.3 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 EGO22752.1 - 2e-33 115.5 0.0 5e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 UQ_con PF00179.26 EGO22753.1 - 8.9e-41 138.8 0.0 1.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGO22753.1 - 0.0064 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 EGO22753.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Complex1_LYR PF05347.15 EGO22753.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) RWD PF05773.22 EGO22753.1 - 0.062 13.6 0.1 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 RWD domain Synaptobrevin PF00957.21 EGO22755.1 - 8.4e-15 54.3 1.0 1.6e-14 53.4 1.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGO22755.1 - 3.1e-11 43.1 0.0 6.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain RuBisCO_large PF00016.20 EGO22756.1 - 0.063 12.5 0.1 0.063 12.5 0.1 1.0 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain NACHT PF05729.12 EGO22759.1 - 0.00019 21.4 0.0 0.00047 20.1 0.0 1.7 2 1 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EGO22759.1 - 0.00052 20.4 0.0 0.067 13.6 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EGO22759.1 - 0.00064 20.0 0.0 0.00094 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGO22759.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGO22759.1 - 0.016 15.6 0.0 0.039 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EGO22759.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGO22759.1 - 0.077 12.2 0.3 0.13 11.5 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EGO22759.1 - 0.086 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 EGO22759.1 - 0.099 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EGO22759.1 - 0.11 12.4 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Ribosomal_L38e PF01781.18 EGO22763.1 - 1.5e-29 101.9 1.0 1.7e-29 101.7 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Peptidase_M50 PF02163.22 EGO22764.1 - 1.8e-10 40.5 0.0 0.00011 21.6 0.3 3.1 2 1 0 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 EGO22764.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain ParA PF10609.9 EGO22765.1 - 6e-75 251.9 0.0 8.1e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGO22765.1 - 7e-10 39.0 0.0 7.5e-09 35.7 0.0 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGO22765.1 - 2e-07 31.1 0.8 6.4e-06 26.2 0.3 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EGO22765.1 - 0.0017 17.6 0.6 0.0093 15.2 0.2 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 EGO22765.1 - 0.0038 16.8 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 EGO22765.1 - 0.0067 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 EGO22765.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family An_peroxidase PF03098.15 EGO22766.1 - 6e-13 48.2 0.0 8.6e-05 21.3 0.0 4.0 3 1 1 4 4 4 4 Animal haem peroxidase DUF4678 PF15727.5 EGO22770.1 - 0.036 13.3 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) RabGAP-TBC PF00566.18 EGO22771.1 - 5.7e-26 91.5 0.2 7.5e-26 91.1 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF953 PF06110.11 EGO22772.1 - 1.4e-18 66.6 0.0 1.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 EGO22772.1 - 0.081 13.4 0.0 0.13 12.7 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain FR47 PF08445.10 EGO22773.1 - 7e-10 38.7 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGO22773.1 - 2e-09 37.5 0.0 3.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO22773.1 - 2.8e-09 37.2 0.0 5.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO22773.1 - 7e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO22773.1 - 1.7e-05 24.9 0.0 4.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_pol_L PF01193.24 EGO22773.1 - 0.026 13.9 0.0 1.6 8.2 0.0 2.6 2 1 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Acetyltransf_13 PF13880.6 EGO22773.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 EGO22773.1 - 0.14 12.8 0.0 0.4 11.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy PF03171.20 EGO22774.1 - 1.4e-14 54.3 0.0 3.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGO22774.1 - 5.6e-12 46.4 0.0 1.3e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TM140 PF14985.6 EGO22774.1 - 0.24 10.9 0.0 0.45 10.0 0.0 1.3 1 0 0 1 1 1 0 TM140 protein family ADH_zinc_N_2 PF13602.6 EGO22775.1 - 3.9e-13 50.6 0.0 1.5e-12 48.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO22775.1 - 1.1e-12 48.1 0.0 2.2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO22775.1 - 9.4e-07 28.7 1.7 8.6e-05 22.4 0.1 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGO22775.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EGO22775.1 - 0.053 13.4 0.5 0.08 12.8 0.5 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 EGO22775.1 - 0.074 12.6 0.3 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EGO22775.1 - 0.16 11.5 0.2 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Bac_DNA_binding PF00216.21 EGO22776.1 - 0.21 11.8 0.8 12 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial DNA-binding protein ArAE_2 PF10334.9 EGO22777.1 - 3.6e-54 184.0 0.0 1.5e-53 182.0 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 EGO22777.1 - 9.8e-45 153.5 8.5 1.3e-38 133.2 0.1 4.6 3 1 0 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EGO22777.1 - 1.8e-10 41.1 12.4 1.8e-10 41.1 12.4 3.8 3 1 1 4 4 4 1 Fusaric acid resistance protein-like UPF0139 PF03669.13 EGO22777.1 - 0.0044 16.9 0.3 0.02 14.7 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0139) HIT PF01230.23 EGO22778.1 - 1.2e-21 77.3 0.2 1.9e-21 76.6 0.1 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EGO22778.1 - 7.4e-13 49.0 0.0 1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGO22778.1 - 0.00086 19.2 0.2 0.0015 18.4 0.2 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 YcxB PF14317.6 EGO22778.1 - 0.086 12.6 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 YcxB-like protein UPF0016 PF01169.19 EGO22779.1 - 1.5e-44 150.2 18.7 1e-23 83.5 6.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 LysE PF01810.18 EGO22779.1 - 0.0027 17.2 10.0 0.33 10.4 0.8 3.0 2 1 0 2 2 2 2 LysE type translocator DUF3995 PF13160.6 EGO22779.1 - 0.011 16.2 5.5 0.32 11.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Mntp PF02659.15 EGO22779.1 - 0.027 14.2 0.4 0.027 14.2 0.4 2.3 2 0 0 2 2 2 0 Putative manganese efflux pump NnrS PF05940.12 EGO22779.1 - 0.43 9.9 14.4 0.044 13.2 5.3 2.1 2 0 0 2 2 2 0 NnrS protein TerC PF03741.16 EGO22779.1 - 1.2 8.7 9.1 0.39 10.4 1.9 2.6 2 2 0 2 2 2 0 Integral membrane protein TerC family CinA PF02464.17 EGO22780.1 - 2.6e-29 101.8 0.4 3.1e-29 101.6 0.4 1.0 1 0 0 1 1 1 1 Competence-damaged protein 2OG-FeII_Oxy PF03171.20 EGO22782.1 - 1.4e-14 54.4 0.0 2.9e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGO22782.1 - 7.1e-12 46.1 0.0 1.5e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Retrotran_gag_2 PF14223.6 EGO22783.1 - 6.7e-05 22.6 0.2 0.042 13.5 0.0 2.3 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type 2OG-FeII_Oxy PF03171.20 EGO22784.1 - 9.5e-14 51.7 0.0 2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGO22784.1 - 8.2e-10 39.5 0.0 2.5e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal NACHT PF05729.12 EGO22786.1 - 1.4e-08 34.8 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGO22786.1 - 1.2e-07 32.1 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO22786.1 - 1.5e-06 28.7 0.0 2.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 EGO22786.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 EGO22786.1 - 0.0017 17.7 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EGO22786.1 - 0.0032 17.9 0.0 0.012 16.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGO22786.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EGO22786.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IIGP PF05049.13 EGO22786.1 - 0.067 12.2 0.1 0.092 11.8 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RNA_helicase PF00910.22 EGO22786.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Ank_2 PF12796.7 EGO22787.1 - 0.0017 18.9 0.0 0.0022 18.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO22787.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeat DUF5441 PF17513.2 EGO22787.1 - 0.062 13.0 0.0 0.084 12.6 0.0 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF5441) Ank_4 PF13637.6 EGO22787.1 - 0.094 13.3 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Epimerase PF01370.21 EGO22789.1 - 1.5e-07 31.1 0.0 0.00093 18.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO22789.1 - 5e-07 29.5 0.0 7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO22789.1 - 7e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGO22789.1 - 1.3e-06 28.9 0.1 3e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EGO22789.1 - 0.032 13.4 0.0 0.15 11.2 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.16 EGO22789.1 - 0.079 13.7 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase LSM PF01423.22 EGO22790.1 - 1.5e-17 63.0 0.2 1.7e-17 62.8 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO22790.1 - 6.8e-05 22.9 0.1 8.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain UL42 PF17638.2 EGO22790.1 - 0.91 9.5 5.0 1.2 9.1 5.0 1.2 1 0 0 1 1 1 0 HCMV UL42 Ras PF00071.22 EGO22791.1 - 9.6e-38 129.3 0.0 8.1e-36 123.1 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGO22791.1 - 4.7e-29 101.0 0.0 7.1e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO22791.1 - 3.5e-08 33.1 0.0 2.5e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO22791.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO22791.1 - 0.0029 17.2 0.0 0.009 15.6 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO22791.1 - 0.0038 16.6 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGO22791.1 - 0.15 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGO22791.1 - 0.24 11.1 0.0 0.67 9.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MAP65_ASE1 PF03999.12 EGO22791.1 - 0.34 9.5 5.3 0.47 9.1 5.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RsgA_GTPase PF03193.16 EGO22791.1 - 1 9.2 2.5 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase QWRF PF04484.12 EGO22791.1 - 1.5 8.5 7.2 2.6 7.7 7.2 1.4 1 0 0 1 1 1 0 QWRF family CorA PF01544.18 EGO22792.1 - 3.3e-09 36.5 10.3 8.9e-09 35.1 10.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.18 EGO22793.1 - 2.6e-05 23.7 7.8 6.4e-05 22.4 7.8 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Dzip-like_N PF13815.6 EGO22793.1 - 0.055 13.4 0.9 0.13 12.2 0.3 1.8 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal CorA PF01544.18 EGO22794.1 - 1.7e-13 50.6 2.1 2.7e-13 49.9 2.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ArsB PF02040.15 EGO22795.1 - 5e-08 32.7 20.6 7.9e-05 22.2 11.3 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 EGO22795.1 - 1.1e-07 31.4 34.4 0.00047 19.5 19.2 2.3 1 1 0 2 2 2 2 Citrate transporter Peptidase_C54 PF03416.19 EGO22797.1 - 1.2e-102 343.1 0.0 1.5e-102 342.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 FAD_binding_4 PF01565.23 EGO22798.1 - 1.1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO22798.1 - 2.7e-07 30.6 0.1 7.3e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like CLP_protease PF00574.23 EGO22798.1 - 0.21 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Clp protease PSDC PF12588.8 EGO22799.1 - 9.6e-40 135.8 0.2 1.4e-39 135.2 0.2 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EGO22799.1 - 1.1e-39 136.0 0.0 1.8e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AHSA1 PF08327.11 EGO22799.1 - 0.018 15.3 0.0 7.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein DUF952 PF06108.12 EGO22800.1 - 2.3e-21 75.6 0.0 3.2e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) ROS_MUCR PF05443.11 EGO22802.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Retrotran_gag_2 PF14223.6 EGO22805.1 - 9.4e-10 38.3 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO22805.1 - 5.9e-05 22.6 0.1 0.00011 21.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO22805.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type tRNA-synt_1 PF00133.22 EGO22806.1 - 5.6e-215 715.1 0.0 6.8e-214 711.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGO22806.1 - 5e-34 117.5 0.1 1e-33 116.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGO22806.1 - 2.8e-14 52.7 0.1 8.1e-07 28.1 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGO22806.1 - 2.5e-11 43.5 0.1 6.8e-08 32.2 0.1 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EGO22806.1 - 2.5e-05 24.5 1.8 8.2e-05 22.8 1.8 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EGO22806.1 - 0.049 13.0 0.0 2.1 7.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC1 PF03109.16 EGO22807.1 - 7.2e-31 106.8 0.2 1.5e-30 105.8 0.2 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGO22807.1 - 0.011 15.7 0.1 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF21 PF01595.20 EGO22808.1 - 4.3e-34 117.7 0.1 7.5e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain SOCS PF12610.8 EGO22808.1 - 0.62 10.5 3.5 0.35 11.3 0.4 2.1 2 0 0 2 2 2 0 Suppressor of cytokine signalling Sacchrp_dh_C PF16653.5 EGO22809.1 - 7.7e-75 252.4 0.0 1.2e-74 251.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGO22809.1 - 6.5e-18 65.3 0.1 1.3e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 EGO22809.1 - 2.3e-10 40.9 0.0 8.4e-10 39.1 0.0 2.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGO22809.1 - 0.00015 21.1 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EGO22809.1 - 0.00025 21.1 0.3 0.0006 19.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EGO22809.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Sec_GG PF07549.14 EGO22810.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif DUF846 PF05832.12 EGO22816.1 - 2.3e-53 180.0 7.6 3e-53 179.6 7.6 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Myelin_PLP PF01275.19 EGO22816.1 - 0.011 15.6 2.8 0.017 15.0 2.8 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF2207 PF09972.9 EGO22816.1 - 2.1 7.0 5.9 4.4 5.9 0.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF885 PF05960.11 EGO22818.1 - 0.043 13.5 0.0 0.046 13.4 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FlxA PF14282.6 EGO22818.1 - 0.068 13.2 0.1 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein DASH_Hsk3 PF08227.11 EGO22818.1 - 0.67 10.4 4.2 1 9.8 1.7 2.1 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like zf-CCHC_3 PF13917.6 EGO22819.1 - 1.1e-06 28.5 1.2 2.1e-06 27.6 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO22819.1 - 8.8e-06 25.6 5.1 1.3e-05 25.0 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO22819.1 - 0.041 13.4 0.9 0.07 12.6 0.8 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC PF00098.23 EGO22820.1 - 1.3e-07 31.4 4.1 2e-07 30.8 4.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO22820.1 - 0.00046 20.1 3.2 0.00046 20.1 3.2 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO22820.1 - 0.37 10.7 1.3 0.56 10.1 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO22820.1 - 0.9 9.3 2.9 1.5 8.6 2.9 1.3 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.16 EGO22824.1 - 5.9e-19 68.2 17.5 7.6e-14 51.4 12.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EGO22825.1 - 5.2e-47 160.7 0.0 8.2e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.20 EGO22826.1 - 2e-07 31.3 0.8 0.00013 22.2 0.1 2.4 3 0 0 3 3 3 2 Thioesterase domain Abhydrolase_6 PF12697.7 EGO22826.1 - 1.4e-06 29.1 6.8 2.6e-06 28.2 6.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO22826.1 - 0.044 13.4 0.1 0.096 12.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGO22826.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Y_phosphatase3 PF13350.6 EGO22828.1 - 7.7e-49 166.7 0.0 1.1e-47 163.0 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO22828.1 - 6.3e-06 25.9 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGO22828.1 - 8.6e-05 22.2 0.1 0.001 18.7 0.0 2.5 1 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EGO22828.1 - 0.00067 19.5 0.2 0.0038 17.0 0.0 2.2 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO22828.1 - 0.0064 15.5 0.1 0.0084 15.1 0.1 1.3 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 EGO22828.1 - 0.0088 16.2 6.3 0.11 12.6 6.3 2.4 1 1 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EGO22828.1 - 0.016 15.5 0.5 0.062 13.6 0.0 2.0 2 0 0 2 2 2 0 Rit1 DUSP-like domain HSP70 PF00012.20 EGO22828.1 - 0.15 10.2 7.3 0.2 9.8 7.3 1.1 1 0 0 1 1 1 0 Hsp70 protein UPF0061 PF02696.14 EGO22828.1 - 0.2 10.4 4.3 0.23 10.2 3.3 1.5 1 1 1 2 2 2 0 Uncharacterized ACR, YdiU/UPF0061 family PDCD2_C PF04194.13 EGO22828.1 - 0.38 10.8 8.8 0.41 10.7 8.1 1.4 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Fib_alpha PF08702.10 EGO22828.1 - 0.79 9.9 7.6 0.43 10.8 4.9 1.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Tox-ODYAM1 PF15642.6 EGO22828.1 - 1 8.3 7.3 1.4 7.8 7.3 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF4337 PF14235.6 EGO22828.1 - 4 7.5 10.7 7.3 6.7 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ax_dynein_light PF10211.9 EGO22828.1 - 7 6.5 18.4 8.4 6.3 0.6 2.4 1 1 0 2 2 2 0 Axonemal dynein light chain Lyase_aromatic PF00221.19 EGO22829.1 - 5.9e-137 457.1 5.6 7.9e-137 456.7 5.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase DASH_Spc19 PF08287.11 EGO22829.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Spc19 MFS_1 PF07690.16 EGO22830.1 - 1.5e-40 139.2 58.3 1.5e-40 139.2 58.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO22830.1 - 1.5e-12 47.2 10.3 1.5e-12 47.2 10.3 3.3 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGO22830.1 - 1.2e-07 30.6 14.9 1.2e-07 30.6 14.9 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 EGO22831.1 - 1.1e-141 472.3 0.0 2.1e-73 247.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGO22831.1 - 2.7e-39 135.1 0.0 9.1e-25 87.2 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EGO22831.1 - 3.9e-19 68.8 0.3 1e-08 35.4 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGO22831.1 - 2.1e-10 41.4 2.1 2.7e-07 31.4 0.1 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EGO22831.1 - 0.056 12.3 0.0 2 7.2 0.0 2.9 3 0 0 3 3 3 0 GH3 auxin-responsive promoter Y_phosphatase3 PF13350.6 EGO22832.1 - 1.6e-52 178.8 0.0 1.9e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO22832.1 - 7.5e-05 22.4 0.0 9.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGO22832.1 - 0.00093 18.8 0.0 0.0022 17.6 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGO22832.1 - 0.0058 16.5 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGO22832.1 - 0.057 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate gag-asp_proteas PF13975.6 EGO22834.1 - 3.9e-05 24.1 0.0 4.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO22834.1 - 0.00013 22.6 0.0 0.00016 22.3 0.0 1.2 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO22834.1 - 0.0031 17.3 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Plavaka PF18759.1 EGO22837.1 - 2.8e-65 220.7 3.1 1.3e-52 179.1 0.0 2.4 1 1 1 2 2 2 2 Plavaka transposase KDZ PF18758.1 EGO22840.1 - 2.3e-15 56.8 0.0 1.6e-11 44.3 0.0 2.4 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Thioredoxin PF00085.20 EGO22840.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Get5_C PF18514.1 EGO22841.1 - 0.017 14.8 0.0 0.34 10.7 0.0 2.7 2 0 0 2 2 2 0 Get5 C-terminal domain Retrotrans_gag PF03732.17 EGO22842.1 - 1e-05 25.7 0.8 1.9e-05 24.9 0.6 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 EGO22843.1 - 6.1e-07 29.6 1.5 9.6e-07 29.0 1.5 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO22843.1 - 0.0019 18.2 1.1 0.003 17.6 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO22843.1 - 0.13 12.1 0.8 0.29 10.9 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Menin PF05053.13 EGO22845.1 - 5.3 5.3 8.0 8.2 4.6 8.0 1.3 1 0 0 1 1 1 0 Menin Cellulase PF00150.18 EGO22846.1 - 3.5e-33 115.2 2.4 6.6e-33 114.3 2.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RNase_PH PF01138.21 EGO22847.1 - 1.3e-20 74.3 0.0 1.9e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Polysacc_deac_1 PF01522.21 EGO22848.1 - 1.5e-27 95.9 0.0 4.4e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Aspzincin_M35 PF14521.6 EGO22848.1 - 0.03 14.9 3.5 2.2 8.8 0.7 2.4 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Secretin_N_2 PF07655.13 EGO22848.1 - 0.38 11.3 14.0 2 9.0 10.6 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain ENTH PF01417.20 EGO22849.1 - 2.7e-51 172.8 0.1 4.6e-51 172.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGO22849.1 - 0.0006 18.9 0.0 0.0006 18.9 0.0 2.2 2 0 0 2 2 2 1 ANTH domain Chisel PF15355.6 EGO22849.1 - 0.04 14.1 0.4 0.11 12.7 0.4 1.8 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel Hydrophobin PF01185.18 EGO22850.1 - 9.4e-18 64.6 5.3 1.6e-17 63.9 5.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EGO22851.1 - 2.3e-18 66.6 5.8 3.2e-18 66.1 5.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Beta-prism_lec PF16458.5 EGO22852.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-prism lectin Peptidase_M24 PF00557.24 EGO22853.1 - 9.8e-59 198.5 0.0 1.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGO22853.1 - 4.5e-17 61.9 0.0 7.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain 5_nucleotid_C PF02872.18 EGO22855.1 - 9.8e-27 94.1 0.0 3e-25 89.3 0.0 2.5 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain p450 PF00067.22 EGO22856.1 - 1e-58 199.3 0.0 1.5e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynactin PF12455.8 EGO22856.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Dynein associated protein Oxidored_FMN PF00724.20 EGO22859.1 - 4.3e-38 131.4 0.0 5.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGO22859.1 - 0.0058 15.8 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Phosphatase PF15698.5 EGO22859.1 - 0.032 13.4 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphatase HMGL-like PF00682.19 EGO22859.1 - 0.057 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 HMGL-like DUF1184 PF06683.11 EGO22860.1 - 0.19 11.2 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) zf-CCHC_4 PF14392.6 EGO22862.1 - 0.057 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGO22862.1 - 0.071 13.0 1.3 1.1 9.1 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO22862.1 - 0.095 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Kdo PF06293.14 EGO22863.1 - 2.5e-09 36.8 0.0 7.7e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO22863.1 - 2.7e-06 27.5 0.0 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGO22863.1 - 1.5e-05 24.5 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 EGO22863.1 - 4.8e-05 22.8 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EGO22863.1 - 0.00018 21.1 0.0 0.03 13.9 0.1 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 EGO22863.1 - 0.0078 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EGO22863.1 - 0.017 14.5 0.0 0.043 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Ion_trans PF00520.31 EGO22864.1 - 1.3e-126 420.8 105.7 1.6e-37 129.0 8.9 5.1 5 0 0 5 5 5 5 Ion transport protein SEP PF08059.13 EGO22865.1 - 9.8e-24 83.7 0.3 5.2e-23 81.4 0.0 2.3 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EGO22865.1 - 7.8e-14 51.6 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain Methyltransf_16 PF10294.9 EGO22866.1 - 4.4e-14 52.6 0.0 6.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EGO22866.1 - 0.0055 16.1 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Sugar_tr PF00083.24 EGO22867.1 - 4.8e-124 414.7 26.2 5.5e-124 414.5 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO22867.1 - 4.9e-19 68.5 50.6 5.2e-14 51.9 16.6 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2530 PF10745.9 EGO22867.1 - 1.3 9.4 7.3 0.31 11.3 1.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) PI-PLC-X PF00388.19 EGO22869.1 - 1.4e-38 131.7 0.0 2.4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGO22869.1 - 2.4e-30 105.2 0.0 4.3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGO22869.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain PIN_4 PF13638.6 EGO22870.1 - 6.2e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 PIN domain DUF2347 PF09804.9 EGO22871.1 - 5.9e-45 154.0 0.0 8.5e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EGO22871.1 - 0.00094 18.0 0.0 4.6 5.8 0.1 3.1 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.10 EGO22871.1 - 0.0088 16.0 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Prefoldin PF02996.17 EGO22872.1 - 9.5e-31 106.2 3.0 1.1e-30 106.0 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EGO22872.1 - 0.00022 21.2 0.9 0.00041 20.3 0.6 1.6 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGO22872.1 - 0.0037 17.2 5.7 0.069 13.1 0.7 2.1 2 0 0 2 2 2 2 Prefoldin subunit COG2 PF06148.11 EGO22872.1 - 0.01 15.9 1.4 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AIP3 PF03915.13 EGO22872.1 - 0.014 14.6 3.2 0.017 14.3 3.2 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Spc7 PF08317.11 EGO22872.1 - 0.02 13.8 6.3 0.068 12.1 0.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EGO22872.1 - 0.024 14.8 7.6 1.6 8.9 7.6 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Med30 PF11315.8 EGO22872.1 - 0.025 14.8 4.6 0.31 11.2 3.8 2.1 1 1 0 1 1 1 0 Mediator complex subunit 30 CLZ PF16526.5 EGO22872.1 - 0.027 14.8 3.5 4.6 7.7 0.2 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Seryl_tRNA_N PF02403.22 EGO22872.1 - 0.031 14.5 2.1 2.9 8.1 0.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4709 PF15821.5 EGO22872.1 - 0.037 14.3 3.3 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) PHM7_cyt PF14703.6 EGO22872.1 - 0.044 14.0 1.1 0.079 13.2 1.1 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter XkdW PF09636.10 EGO22872.1 - 0.045 13.8 1.3 0.12 12.5 0.3 1.9 2 0 0 2 2 2 0 XkdW protein DUF1664 PF07889.12 EGO22872.1 - 0.075 13.1 4.3 3.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC2_membrane_3 PF12698.7 EGO22872.1 - 0.083 12.0 4.2 0.094 11.8 4.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein EAP30 PF04157.16 EGO22872.1 - 0.088 12.1 2.0 1.1 8.4 0.4 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family UPF0449 PF15136.6 EGO22872.1 - 0.25 11.8 4.7 2.9 8.4 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Fzo_mitofusin PF04799.13 EGO22872.1 - 0.27 10.8 4.0 0.58 9.7 0.5 2.1 2 0 0 2 2 2 0 fzo-like conserved region XhlA PF10779.9 EGO22872.1 - 0.29 11.4 1.9 11 6.3 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Filament PF00038.21 EGO22872.1 - 0.38 10.3 7.6 0.36 10.4 1.7 2.0 1 1 0 2 2 2 0 Intermediate filament protein Sec2p PF06428.11 EGO22872.1 - 0.46 10.5 8.2 1.8 8.6 2.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Baculo_PEP_C PF04513.12 EGO22872.1 - 0.56 10.2 6.1 5.9 6.9 0.8 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 EGO22872.1 - 2.4 8.5 7.7 26 5.2 7.7 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region F-box-like PF12937.7 EGO22873.1 - 0.0013 18.6 0.2 0.0033 17.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like Pro_isomerase PF00160.21 EGO22874.1 - 1.8e-49 168.1 0.4 2e-49 167.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mito_fiss_reg PF05308.11 EGO22876.1 - 1.9 8.5 6.7 2.5 8.1 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DSPc PF00782.20 EGO22878.1 - 6.8e-07 29.2 0.0 9.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGO22878.1 - 7.1e-07 29.5 0.1 3.2e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGO22878.1 - 3.2e-05 24.0 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO22878.1 - 0.0017 17.9 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.13 EGO22878.1 - 0.0035 17.4 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase (DUF442) DUF1643 PF07799.12 EGO22878.1 - 0.0043 17.2 0.0 0.0051 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1643) Y_phosphatase2 PF03162.13 EGO22878.1 - 0.0053 16.4 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Dak1 PF02733.17 EGO22879.1 - 7.1e-89 297.8 0.8 7.3e-87 291.1 0.8 2.1 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGO22879.1 - 4.9e-36 124.2 0.8 1e-35 123.2 0.8 1.6 1 1 0 1 1 1 1 DAK2 domain Bac_rhamnosid_N PF08531.10 EGO22882.1 - 0.06 13.2 0.4 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain Aldo_ket_red PF00248.21 EGO22883.1 - 2.2e-36 125.6 0.0 9.2e-30 103.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family IPT PF01745.16 EGO22883.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Aldo_ket_red PF00248.21 EGO22884.1 - 1.3e-38 132.9 0.0 4.5e-36 124.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family IPT PF01745.16 EGO22884.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Aldo_ket_red PF00248.21 EGO22885.1 - 6.7e-46 156.8 0.3 1.1e-43 149.6 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Beta_elim_lyase PF01212.21 EGO22885.1 - 0.033 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Bac_rhamnosid_N PF08531.10 EGO22887.1 - 0.092 12.6 0.7 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain Dynamin_M PF01031.20 EGO22889.1 - 6.2e-31 107.7 0.1 2.8e-30 105.5 0.0 2.0 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGO22889.1 - 3.3e-16 59.8 0.0 5.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGO22889.1 - 1.1e-10 41.5 0.2 1.1e-10 41.5 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain EF-hand_9 PF14658.6 EGO22889.1 - 0.02 15.2 0.0 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain MMR_HSR1 PF01926.23 EGO22889.1 - 0.15 12.1 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase CybS PF05328.12 EGO22890.1 - 1.7e-43 147.5 0.1 2.1e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit LamB_YcsF PF03746.16 EGO22892.1 - 9.8e-83 277.5 0.0 1.2e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF4267 PF14087.6 EGO22894.1 - 2.8e-27 95.0 1.2 3.3e-27 94.8 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4044 PF13253.6 EGO22894.1 - 0.096 12.2 0.5 0.096 12.2 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4044) CT_A_B PF02626.15 EGO22895.1 - 4.5e-78 262.5 0.0 6.5e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EGO22895.1 - 1.4e-56 191.3 0.0 2.6e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 EGO22895.1 - 5.1e-35 121.1 0.0 9.8e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 EGO22895.1 - 4e-34 117.5 0.0 1.9e-33 115.3 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGO22895.1 - 2.8e-29 101.4 0.0 6.6e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EGO22895.1 - 7.2e-10 38.7 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 EGO22895.1 - 0.00034 20.4 0.8 0.0011 18.8 0.8 1.9 1 1 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.11 EGO22895.1 - 0.027 14.1 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain YqhG PF11079.8 EGO22895.1 - 0.082 11.9 0.6 0.16 10.9 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Biotin_lipoyl_2 PF13533.6 EGO22895.1 - 0.12 12.2 0.1 23 4.9 0.1 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like F-box-like PF12937.7 EGO22896.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like PS_Dcarbxylase PF02666.15 EGO22898.1 - 1.5e-40 138.9 0.0 2.7e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EGO22898.1 - 8e-40 136.1 0.1 1.1e-39 135.6 0.1 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 EGO22898.1 - 0.0098 15.8 0.0 0.034 14.1 0.0 1.8 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EGO22898.1 - 0.14 12.0 0.2 0.35 10.7 0.1 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme F-box-like PF12937.7 EGO22901.1 - 0.00012 21.9 6.2 0.00021 21.1 0.1 3.6 3 1 1 4 4 4 1 F-box-like Cys_rich_VLP PF14194.6 EGO22901.1 - 0.017 15.2 0.0 0.47 10.6 0.0 2.8 2 0 0 2 2 2 0 Cysteine-rich VLP LRR_8 PF13855.6 EGO22901.1 - 0.19 11.5 0.9 21 5.0 0.2 3.7 4 0 0 4 4 4 0 Leucine rich repeat Ubiq_cyt_C_chap PF03981.12 EGO22902.1 - 3.9e-07 30.3 0.0 4.3e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF3952 PF13130.6 EGO22904.1 - 0.049 13.8 0.2 0.063 13.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) Cpn60_TCP1 PF00118.24 EGO22907.1 - 4.1e-86 289.5 5.6 7.1e-86 288.8 5.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family polyprenyl_synt PF00348.17 EGO22908.1 - 2.8e-94 314.9 0.0 3.6e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3770 PF12603.8 EGO22908.1 - 0.013 15.0 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) MMR_HSR1 PF01926.23 EGO22910.1 - 5.3e-11 42.6 0.0 8.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGO22910.1 - 4.7e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EGO22910.1 - 9.1e-05 23.0 0.3 0.0029 18.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EGO22910.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 EGO22910.1 - 0.00041 20.0 0.0 0.00068 19.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 EGO22910.1 - 0.0013 18.8 0.4 0.0041 17.2 0.4 1.7 1 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGO22910.1 - 0.0041 17.1 0.2 0.0094 15.9 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGO22910.1 - 0.005 17.2 0.1 0.012 16.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EGO22910.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EGO22910.1 - 0.015 15.0 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EGO22910.1 - 0.043 13.4 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.26 EGO22910.1 - 0.048 13.4 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGO22910.1 - 0.064 13.7 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO22910.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.23 EGO22910.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 EGO22910.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_M PF02770.19 EGO22911.1 - 0.00033 20.8 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Asp_protease_2 PF13650.6 EGO22912.1 - 4.5e-05 24.0 0.0 9.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO22912.1 - 0.00018 22.0 0.0 0.00058 20.4 0.0 1.8 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease YejG PF13989.6 EGO22912.1 - 0.072 13.5 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein RNAse_A_bac PF18431.1 EGO22912.1 - 0.073 14.0 0.1 0.1 13.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain Chromo PF00385.24 EGO22914.1 - 5.1e-09 35.9 0.2 5.6e-09 35.8 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EGO22914.1 - 0.001 18.9 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo_shadow PF01393.19 EGO22914.1 - 0.026 14.6 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Chromo shadow domain YicC_N PF03755.13 EGO22914.1 - 0.038 14.5 0.0 0.04 14.4 0.0 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region Mtf2_C PF14061.6 EGO22914.1 - 0.043 14.0 0.3 0.067 13.4 0.2 1.5 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-CCHC PF00098.23 EGO22916.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO22916.1 - 0.0083 15.9 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO22916.1 - 0.043 13.4 0.4 0.062 12.9 0.4 1.3 1 0 0 1 1 1 0 Zinc finger domain DUF1708 PF08101.11 EGO22919.1 - 1.1e-15 57.8 0.0 4.7e-14 52.4 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EGO22919.1 - 0.0082 16.0 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Fascin PF06268.13 EGO22920.1 - 3.3e-20 72.4 0.1 6.6e-05 23.1 0.0 5.0 3 2 2 5 5 5 4 Fascin domain FRG1 PF06229.12 EGO22920.1 - 3.7e-08 33.3 0.3 0.062 13.0 0.0 4.1 3 1 0 3 3 3 3 FRG1-like domain DUF3430 PF11912.8 EGO22920.1 - 0.00032 20.8 7.4 0.09 12.8 0.4 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3430) Neuralized PF07177.12 EGO22920.1 - 0.13 12.3 0.0 1.6 8.7 0.0 2.5 2 1 0 2 2 2 0 Neuralized Fn_bind PF02986.14 EGO22920.1 - 0.29 10.9 0.7 40 4.0 0.0 3.0 3 0 0 3 3 3 0 Fibronectin binding repeat SKG6 PF08693.10 EGO22922.1 - 0.25 10.8 5.3 0.51 9.8 5.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2613 PF11021.8 EGO22922.1 - 1.8 8.7 5.7 1.4 9.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Hydantoinase_A PF01968.18 EGO22924.1 - 8.7e-96 320.6 0.0 1.4e-95 319.9 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGO22924.1 - 5.2e-51 172.9 0.0 5.3e-48 163.1 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Acyl-CoA_dh_M PF02770.19 EGO22925.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1 PF01926.23 EGO22926.1 - 5.3e-11 42.6 0.0 8.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGO22926.1 - 4.7e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EGO22926.1 - 9.1e-05 23.0 0.3 0.0029 18.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EGO22926.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 EGO22926.1 - 0.00041 20.0 0.0 0.00068 19.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 EGO22926.1 - 0.0013 18.8 0.4 0.0041 17.2 0.4 1.7 1 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGO22926.1 - 0.0041 17.1 0.2 0.0094 15.9 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGO22926.1 - 0.005 17.2 0.1 0.012 16.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EGO22926.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EGO22926.1 - 0.015 15.0 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EGO22926.1 - 0.043 13.4 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.26 EGO22926.1 - 0.048 13.4 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGO22926.1 - 0.064 13.7 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO22926.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.23 EGO22926.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 EGO22926.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGO22928.1 - 1.3e-10 41.3 0.0 2.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO22928.1 - 5.2e-06 25.9 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGO22928.1 - 0.00071 19.7 0.4 0.0066 16.5 0.3 2.3 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 EGO22928.1 - 0.0013 19.0 0.1 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EGO22928.1 - 0.0013 19.3 2.3 0.004 17.7 2.3 2.2 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGO22928.1 - 0.0022 17.9 0.0 0.0066 16.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGO22928.1 - 0.0088 16.6 0.6 0.014 15.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO22928.1 - 0.032 14.6 0.1 0.069 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGO22928.1 - 0.068 12.9 0.1 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.22 EGO22928.1 - 0.079 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.18 EGO22928.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_replicase_B PF03431.13 EGO22928.1 - 0.11 11.0 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 RNA replicase, beta-chain VirB8 PF04335.13 EGO22928.1 - 0.12 12.2 0.1 0.66 9.8 0.1 2.0 1 1 1 2 2 2 0 VirB8 protein DUF815 PF05673.13 EGO22928.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4184 PF13803.6 EGO22928.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) Chromo PF00385.24 EGO22929.1 - 1.8e-08 34.1 0.1 2.1e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EGO22929.1 - 0.0011 18.9 0.1 0.0014 18.5 0.1 1.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo_shadow PF01393.19 EGO22929.1 - 0.037 14.1 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Chromo shadow domain Mtf2_C PF14061.6 EGO22929.1 - 0.043 14.0 0.3 0.067 13.4 0.2 1.5 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 YicC_N PF03755.13 EGO22929.1 - 0.059 13.8 0.0 0.063 13.7 0.0 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region Retrotrans_gag PF03732.17 EGO22930.1 - 2.7e-06 27.6 1.0 2.7e-06 27.6 1.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EGO22930.1 - 0.00016 22.3 0.1 0.00095 19.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO22930.1 - 0.0014 19.1 0.0 0.0053 17.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Astro_capsid_p PF12226.8 EGO22931.1 - 0.0064 15.7 2.3 0.01 15.0 2.3 1.3 1 0 0 1 1 1 1 Turkey astrovirus capsid protein SURF2 PF05477.11 EGO22931.1 - 0.035 13.8 0.5 0.05 13.3 0.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 EGO22931.1 - 0.082 12.2 1.5 0.12 11.7 1.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2456 PF10445.9 EGO22932.1 - 0.35 11.0 3.6 0.53 10.4 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Orthopox_F8 PF05886.11 EGO22933.1 - 0.49 10.6 4.4 0.74 10.0 0.4 2.7 3 0 0 3 3 3 0 Orthopoxvirus F8 protein Trm112p PF03966.16 EGO22934.1 - 1.4e-20 73.6 0.1 1.8e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein RNase_PH PF01138.21 EGO22935.1 - 1.7e-18 67.4 0.0 2.8e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGO22935.1 - 2.1e-08 34.1 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Vault_3 PF17795.1 EGO22935.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Major Vault Protein Repeat domain C1_1 PF00130.22 EGO22939.1 - 0.043 13.7 0.7 0.1 12.5 0.7 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH PF01844.23 EGO22939.1 - 0.058 13.6 2.2 0.17 12.1 2.2 1.8 1 1 0 1 1 1 0 HNH endonuclease DUF3337 PF11816.8 EGO22940.1 - 9.8e-54 181.8 0.0 1.6e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EGO22940.1 - 3.2e-19 68.9 13.0 0.00059 20.6 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat RAWUL PF16207.5 EGO22940.1 - 0.0042 17.7 0.0 0.0087 16.7 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like PALB2_WD40 PF16756.5 EGO22940.1 - 0.012 14.5 0.4 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EGO22940.1 - 0.026 13.5 0.0 0.069 12.1 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO22940.1 - 0.11 11.2 3.0 1.1 7.8 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGO22940.1 - 0.12 12.7 0.0 1.6 9.0 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M48 PF01435.18 EGO22941.1 - 4.6e-30 104.9 0.1 8.6e-30 104.0 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M48 DUF3533 PF12051.8 EGO22942.1 - 3.6e-71 240.1 12.4 4.1e-71 239.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CBM_20 PF00686.19 EGO22943.1 - 2.8e-28 97.7 0.7 6.6e-28 96.5 0.4 1.8 2 0 0 2 2 2 1 Starch binding domain Alpha-amylase PF00128.24 EGO22943.1 - 6.8e-11 42.3 0.0 2.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EGO22943.1 - 6.3e-10 39.4 0.0 1.7e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pex14_N PF04695.13 EGO22944.1 - 0.033 14.8 0.7 0.056 14.1 0.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nicastrin PF05450.15 EGO22944.1 - 0.15 11.5 0.2 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 Nicastrin adh_short_C2 PF13561.6 EGO22945.1 - 1.2e-56 191.9 2.0 1.9e-56 191.3 2.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO22945.1 - 3.5e-47 160.4 1.5 4.7e-47 160.0 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO22945.1 - 3e-09 37.0 0.4 4.8e-09 36.4 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO22945.1 - 0.003 17.0 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 EGO22946.1 - 2.4e-58 197.5 3.8 1e-57 195.4 3.8 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO22946.1 - 1.9e-53 180.9 1.6 2.3e-53 180.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO22946.1 - 4.9e-12 46.1 3.6 7.6e-12 45.5 3.2 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGO22946.1 - 0.036 13.5 0.9 0.045 13.2 0.6 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 EGO22946.1 - 0.057 14.1 0.9 0.19 12.4 0.4 1.9 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EGO22946.1 - 0.097 11.8 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Polysacc_deac_1 PF01522.21 EGO22950.1 - 3.2e-14 52.9 0.0 8.1e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase Aldedh PF00171.22 EGO22953.1 - 2.3e-180 600.1 0.0 2.5e-180 599.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1242 PF06842.12 EGO22954.1 - 9e-19 67.0 2.2 1.2e-18 66.6 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 EGO22954.1 - 0.036 14.4 0.5 0.17 12.2 0.6 1.8 2 0 0 2 2 2 0 LST-1 protein DUF805 PF05656.14 EGO22954.1 - 0.083 13.3 0.5 0.091 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) SMC_N PF02463.19 EGO22955.1 - 3.2e-18 66.0 0.0 4.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGO22955.1 - 0.048 13.5 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2481 PF10654.9 EGO22956.1 - 0.0091 16.0 2.6 0.012 15.5 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2481) DUF1204 PF06721.11 EGO22956.1 - 0.017 14.6 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF3583 PF12126.8 EGO22956.1 - 0.11 12.0 0.7 0.14 11.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) SMC_N PF02463.19 EGO22957.1 - 9.4e-37 126.6 0.3 1.2e-36 126.2 0.3 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO22957.1 - 1.7e-13 51.5 0.5 1.9e-13 51.4 0.5 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGO22957.1 - 2.4e-06 27.6 0.1 3.1e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO22957.1 - 7.3e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGO22957.1 - 2.7e-05 24.0 0.3 3.2e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGO22957.1 - 0.044 14.3 2.7 0.11 13.0 2.7 1.8 1 1 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 EGO22957.1 - 0.064 12.8 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EGO22957.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HTH_26 PF13443.6 EGO22957.1 - 0.14 12.6 0.1 25 5.4 0.1 3.0 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain Glyco_hydro_88 PF07470.13 EGO22958.1 - 3.7e-19 69.0 0.1 5.2e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MAD PF05557.13 EGO22960.1 - 5.6e-35 120.9 4.3 1.1e-34 119.9 4.3 1.4 1 1 0 1 1 1 1 Mitotic checkpoint protein AGO_N PF18236.1 EGO22960.1 - 0.024 14.9 0.3 0.024 14.9 0.3 1.8 2 0 0 2 2 2 0 Argonaute N domain LMBR1 PF04791.16 EGO22960.1 - 0.067 12.1 2.3 0.076 11.9 2.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PI3K_P85_iSH2 PF16454.5 EGO22960.1 - 0.2 11.3 9.8 0.33 10.6 9.8 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Atg14 PF10186.9 EGO22960.1 - 0.32 10.1 10.9 0.62 9.1 2.9 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EGO22960.1 - 0.38 10.1 4.3 1.1 8.5 4.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EGO22960.1 - 0.75 9.9 20.4 0.18 11.9 2.6 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EGO22960.1 - 2 9.1 12.6 0.31 11.7 1.0 3.4 3 1 0 3 3 3 0 SlyX V_ATPase_I PF01496.19 EGO22960.1 - 3.3 5.5 4.6 4.2 5.2 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlgN PF05130.12 EGO22960.1 - 4.1 7.9 11.0 0.75 10.3 2.4 2.3 1 1 0 2 2 2 0 FlgN protein GAS PF13851.6 EGO22960.1 - 4.6 6.5 18.1 1.8 7.9 3.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF848 PF05852.11 EGO22960.1 - 5.7 7.0 10.4 0.7 10.0 1.0 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) MerR-DNA-bind PF09278.11 EGO22960.1 - 8.9 6.9 13.1 1.2 9.8 2.2 3.1 3 1 0 3 3 3 0 MerR, DNA binding Fib_alpha PF08702.10 EGO22960.1 - 9 6.5 11.5 5.9 7.1 2.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 EGO22960.1 - 9.8 6.5 15.7 6 7.2 4.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF262 PF03235.14 EGO22961.1 - 1.7e-18 67.6 0.9 3.5e-18 66.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 OPT PF03169.15 EGO22965.1 - 4.2e-194 646.7 67.8 4.8e-194 646.5 67.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PAP_central PF04928.17 EGO22965.1 - 2.6 7.0 4.9 3.1 6.7 1.0 2.3 2 0 0 2 2 2 0 Poly(A) polymerase central domain NIF PF03031.18 EGO22966.1 - 3.1e-12 46.6 0.0 6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2834 PF11196.8 EGO22967.1 - 1.2 9.5 6.9 0.17 12.2 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2834) Phospho_p8 PF10195.9 EGO22968.1 - 0.2 12.2 0.6 0.38 11.3 0.6 1.4 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Ribosomal_L17 PF01196.19 EGO22969.1 - 2.5e-33 114.8 0.1 5.7e-33 113.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 WD40 PF00400.32 EGO22970.1 - 1.4e-20 73.2 19.4 5.7e-05 23.8 1.2 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO22970.1 - 2.2e-07 31.1 4.4 0.091 13.1 0.1 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO22970.1 - 2.1e-06 26.9 0.6 0.051 12.5 0.1 3.0 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GTP_EFTU PF00009.27 EGO22971.1 - 4e-60 202.7 0.0 6.6e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGO22971.1 - 5.8e-36 122.9 0.0 4.2e-35 120.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 EGO22971.1 - 2.2e-29 101.3 0.0 4.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGO22971.1 - 1.4e-22 79.5 0.1 3.3e-22 78.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO22971.1 - 9.5e-11 41.9 0.0 2.2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGO22971.1 - 8.3e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Sec34 PF04136.15 EGO22973.1 - 1e-48 165.0 0.4 4.4e-48 162.9 0.7 1.9 2 0 0 2 2 2 1 Sec34-like family KIP1 PF07765.12 EGO22973.1 - 0.024 14.7 0.6 0.069 13.3 0.6 1.7 1 0 0 1 1 1 0 KIP1-like protein Vps5 PF09325.10 EGO22973.1 - 0.047 13.2 0.6 0.095 12.2 0.6 1.5 1 0 0 1 1 1 0 Vps5 C terminal like BLOC1_2 PF10046.9 EGO22973.1 - 0.052 13.8 1.6 3.2 8.1 0.5 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.13 EGO22973.1 - 0.062 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) KfrA_N PF11740.8 EGO22973.1 - 0.16 12.7 0.3 2.4 8.8 0.0 2.8 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term MMR_HSR1 PF01926.23 EGO22974.1 - 2.7e-17 62.9 0.6 7e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO22974.1 - 4.3e-07 29.6 1.3 3.4e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO22974.1 - 1.5e-06 28.2 0.0 9.1e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase MeaB PF03308.16 EGO22974.1 - 0.0019 17.3 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGO22974.1 - 0.0023 18.0 2.0 0.31 11.1 0.1 3.0 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 EGO22974.1 - 0.01 16.2 0.4 0.36 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 EGO22974.1 - 0.027 13.8 1.4 0.29 10.5 0.2 2.2 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 EGO22974.1 - 0.028 14.0 0.2 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 2-Hacid_dh_C PF02826.19 EGO22974.1 - 0.064 12.6 0.1 1.7 8.0 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4181 PF13789.6 EGO22975.1 - 0.0092 16.2 0.4 0.038 14.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4181) Glyco_trans_2_3 PF13632.6 EGO22976.1 - 1e-05 25.5 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_16 PF00722.21 EGO22978.1 - 7.9e-11 41.7 0.2 2.2e-10 40.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EGO22979.1 - 1.8e-54 184.7 0.3 1.8e-54 184.7 0.3 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO22979.1 - 7.1e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGO22979.1 - 0.0046 16.8 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3611 PF12263.8 EGO22979.1 - 0.14 12.1 2.8 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) LRR_4 PF12799.7 EGO22983.1 - 0.21 12.1 2.1 3.1 8.3 0.7 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Cauli_VI PF01693.16 EGO22986.1 - 4.4e-05 23.7 0.2 6.7e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin NUDIX_2 PF13869.6 EGO22992.1 - 4.2e-84 280.8 0.0 4.8e-84 280.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ras PF00071.22 EGO22993.1 - 5.6e-54 182.1 0.0 6.7e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO22993.1 - 1.1e-31 109.5 0.0 1.6e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO22993.1 - 4.3e-14 52.3 0.0 5.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO22993.1 - 3.1e-07 30.0 0.0 4.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO22993.1 - 5.2e-06 26.5 0.0 8.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO22993.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGO22993.1 - 0.086 13.2 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGO22993.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 EGO22993.1 - 0.27 10.3 0.7 2.8 7.0 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Peptidase_M36 PF02128.15 EGO22996.1 - 1.5e-159 531.1 1.4 1.9e-159 530.8 1.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGO22996.1 - 2.9e-11 43.0 2.0 2.9e-11 43.0 2.0 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGO22996.1 - 0.052 13.4 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_23 PF13489.6 EGO22997.1 - 6.6e-15 55.3 0.0 8.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO22997.1 - 6.7e-08 33.1 0.0 1e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO22997.1 - 1.3e-06 29.0 0.0 2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO22997.1 - 3.1e-06 27.8 0.0 5.9e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO22997.1 - 6.3e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGO22997.1 - 0.035 14.0 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGO22997.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PAP2_3 PF14378.6 EGO22998.1 - 7.5e-25 87.7 22.3 7.5e-25 87.7 22.3 2.2 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EGO22998.1 - 2.3e-09 37.1 8.0 2.3e-09 37.1 8.0 2.6 2 1 0 2 2 2 1 PAP2 superfamily EMC3_TMCO1 PF01956.16 EGO22998.1 - 0.11 12.2 0.4 0.31 10.8 0.4 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2955 PF11168.8 EGO22998.1 - 5.5 6.8 14.1 0.16 11.8 1.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2955) HSP70 PF00012.20 EGO23002.1 - 0.15 10.2 0.0 13 3.8 0.0 2.9 3 0 0 3 3 3 0 Hsp70 protein GTP_cyclohydroI PF01227.22 EGO23003.1 - 0.04 13.3 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I Syntaphilin PF15290.6 EGO23004.1 - 0.0043 16.8 4.0 0.0043 16.8 4.0 1.5 1 1 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp DUF4763 PF15960.5 EGO23004.1 - 0.0085 15.4 6.7 0.015 14.7 6.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) UPF0242 PF06785.11 EGO23004.1 - 0.013 15.7 8.9 0.024 14.8 8.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EGO23004.1 - 0.033 13.3 8.1 0.065 12.3 8.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EGO23004.1 - 0.081 12.5 6.8 0.11 12.0 6.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 EGO23004.1 - 0.093 12.0 7.7 0.27 10.5 7.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 EGO23004.1 - 0.1 11.2 4.4 0.15 10.6 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snapin_Pallidin PF14712.6 EGO23004.1 - 0.14 12.6 6.9 0.58 10.6 6.0 2.5 2 1 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 EGO23004.1 - 0.17 12.5 10.3 0.46 11.0 10.3 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region FAM76 PF16046.5 EGO23004.1 - 0.22 10.9 15.8 0.36 10.1 15.8 1.3 1 0 0 1 1 1 0 FAM76 protein FUSC PF04632.12 EGO23004.1 - 0.29 9.6 3.9 0.46 9.0 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4164 PF13747.6 EGO23004.1 - 0.29 11.4 7.4 3.7 7.9 6.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DHR10 PF18595.1 EGO23004.1 - 0.37 10.9 16.6 0.8 9.8 4.6 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 EGO23004.1 - 0.45 10.5 7.8 2.2 8.3 7.7 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 EGO23004.1 - 0.58 10.5 6.0 1.2 9.5 6.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec34 PF04136.15 EGO23004.1 - 0.67 9.8 7.5 0.31 10.9 5.0 1.6 2 0 0 2 2 1 0 Sec34-like family TMF_TATA_bd PF12325.8 EGO23004.1 - 2.1 8.6 11.7 4.1 7.7 8.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding LMBR1 PF04791.16 EGO23004.1 - 2.3 7.0 4.4 2.9 6.7 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 EGO23004.1 - 3 7.9 6.7 7.1 6.7 4.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EGO23004.1 - 4.6 7.8 12.2 30 5.1 12.4 2.2 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EGO23004.1 - 7.3 6.4 9.1 16 5.3 4.3 2.5 1 1 1 2 2 2 0 Septum formation initiator PhyH PF05721.13 EGO23007.1 - 4e-10 40.3 0.0 6.9e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) dsrm PF00035.26 EGO23008.1 - 0.064 14.0 2.8 0.18 12.5 0.1 3.0 3 0 0 3 3 3 0 Double-stranded RNA binding motif SNARE_assoc PF09335.11 EGO23009.1 - 1.4e-14 54.6 10.0 1.4e-14 54.6 10.0 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein Pox_EPC_I2-L1 PF12575.8 EGO23009.1 - 1.2 9.4 7.3 1.5 9.1 1.4 2.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Pkinase PF00069.25 EGO23010.1 - 2.6e-39 135.2 0.0 4.1e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23010.1 - 5.6e-38 130.7 0.0 7.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO23010.1 - 3.7e-05 23.8 0.1 9.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4238 PF14022.6 EGO23010.1 - 7.6e-05 22.4 0.0 0.0064 16.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4238) RIO1 PF01163.22 EGO23010.1 - 0.14 11.7 0.3 1 8.9 0.0 2.5 3 0 0 3 3 3 0 RIO1 family Fructosamin_kin PF03881.14 EGO23010.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Questin_oxidase PF14027.6 EGO23011.1 - 1.2e-102 343.9 0.1 1.5e-102 343.7 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 EGO23012.1 - 1.4e-94 317.4 0.1 1.7e-94 317.2 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like Peptidase_S9 PF00326.21 EGO23013.1 - 2.2e-37 128.6 0.0 3.9e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGO23013.1 - 2.1e-08 34.0 0.0 4.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGO23013.1 - 7.7e-07 28.6 0.1 4.9e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO23013.1 - 1.7e-05 24.6 0.6 0.0062 16.2 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold PD40 PF07676.12 EGO23013.1 - 3.7e-05 23.6 0.7 0.018 15.0 0.1 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 EGO23013.1 - 9.6e-05 22.4 0.1 0.0017 18.3 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EGO23013.1 - 0.00023 21.1 0.1 0.0026 17.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGO23013.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 EGO23013.1 - 0.0028 17.0 0.6 0.46 9.7 0.0 2.3 2 0 0 2 2 2 2 Secretory lipase Hydantoinase_B PF02538.14 EGO23013.1 - 0.0071 14.8 0.0 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase AXE1 PF05448.12 EGO23013.1 - 0.018 13.7 0.2 0.036 12.7 0.2 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EGO23013.1 - 0.043 13.6 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 EGO23013.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 EGO23014.1 - 1.7e-36 125.7 0.2 3.5e-36 124.7 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGO23014.1 - 3.9e-06 26.3 0.1 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PD40 PF07676.12 EGO23014.1 - 2.7e-05 24.0 4.0 0.048 13.6 0.1 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 EGO23014.1 - 4.3e-05 23.5 0.1 0.00018 21.5 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGO23014.1 - 6.7e-05 22.5 0.4 0.00027 20.5 0.3 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 EGO23014.1 - 0.0011 17.7 0.4 0.0088 14.7 0.4 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EGO23014.1 - 0.0023 17.8 0.2 0.012 15.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGO23014.1 - 0.0034 17.1 0.7 0.14 11.8 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGO23014.1 - 0.0044 16.7 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 EGO23014.1 - 0.0097 15.3 0.3 0.096 12.0 0.0 2.2 1 1 0 2 2 2 1 Secretory lipase Peptidase_S15 PF02129.18 EGO23014.1 - 0.025 14.2 0.0 7 6.2 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF5050 PF16472.5 EGO23014.1 - 0.064 12.5 0.0 0.2 10.9 0.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5050) Peptidase_S9 PF00326.21 EGO23015.1 - 1.7e-35 122.4 0.1 3.2e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EGO23015.1 - 2.6e-05 24.0 2.7 0.054 13.5 0.2 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat LIP PF03583.14 EGO23015.1 - 6.8e-05 22.3 0.0 0.025 13.9 0.0 2.2 1 1 1 2 2 2 2 Secretory lipase BAAT_C PF08840.11 EGO23015.1 - 8.9e-05 22.5 0.2 0.00061 19.8 0.2 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EGO23015.1 - 0.00012 21.8 0.1 0.022 14.3 0.3 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EGO23015.1 - 0.00016 21.6 0.2 0.00059 19.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EGO23015.1 - 0.00037 20.1 0.3 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 EGO23015.1 - 0.0045 15.7 0.1 0.019 13.7 0.1 1.9 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EGO23015.1 - 0.0061 15.9 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO23015.1 - 0.0093 15.6 0.1 2.3 7.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO23015.1 - 0.033 14.0 0.0 0.67 9.7 0.0 2.3 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF5050 PF16472.5 EGO23015.1 - 0.075 12.3 0.2 0.15 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) DUF2920 PF11144.8 EGO23015.1 - 0.09 11.9 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) DPPIV_N PF00930.21 EGO23015.1 - 0.092 11.5 0.2 7.1 5.3 0.0 2.8 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PSGP PF07276.11 EGO23015.1 - 0.5 10.8 1.8 1.2 9.7 1.8 1.6 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) Cys_Met_Meta_PP PF01053.20 EGO23016.1 - 5.2e-144 479.5 0.0 5.9e-144 479.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGO23016.1 - 2.8e-12 46.5 0.0 4.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGO23016.1 - 5.6e-11 42.3 0.5 2e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGO23016.1 - 3.4e-09 36.1 0.3 6.7e-09 35.2 0.3 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EGO23016.1 - 0.00011 20.9 0.0 0.00014 20.5 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EGO23016.1 - 0.00025 20.4 0.0 0.00054 19.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Asparaginase_C PF17763.1 EGO23016.1 - 0.024 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 EGO23016.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Questin_oxidase PF14027.6 EGO23017.1 - 4.8e-82 276.2 0.2 5.9e-82 275.9 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like F-box-like PF12937.7 EGO23018.1 - 0.00028 20.7 0.3 0.00062 19.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like FA_hydroxylase PF04116.13 EGO23019.1 - 8e-24 84.5 20.1 8e-24 84.5 20.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Xan_ur_permease PF00860.20 EGO23020.1 - 2.8e-29 102.0 26.5 3.1e-28 98.6 26.5 2.1 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EGO23020.1 - 0.0063 16.9 4.8 0.0063 16.9 4.8 2.9 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 EGO23020.1 - 0.26 11.0 2.9 0.23 11.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) EPL1 PF10513.9 EGO23025.1 - 1.9e-22 80.4 1.0 9.1e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 Enhancer of polycomb-like Leucyl-specific PF14795.6 EGO23025.1 - 0.19 11.8 0.3 0.48 10.5 0.3 1.6 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain zf-H2C2_2 PF13465.6 EGO23027.1 - 2.2e-08 34.2 0.3 2.2e-08 34.2 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGO23027.1 - 1.5e-06 28.3 20.0 3e-06 27.4 0.6 4.4 4 1 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 EGO23027.1 - 3.3e-05 24.4 7.5 0.17 12.6 0.1 3.0 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 EGO23027.1 - 0.0089 16.4 0.1 5.1 7.6 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EGO23027.1 - 0.0094 16.2 0.9 0.019 15.2 0.9 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EGO23027.1 - 0.026 15.3 0.5 0.026 15.3 0.5 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO23027.1 - 0.036 14.1 1.3 0.077 13.0 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1644 PF07800.12 EGO23027.1 - 0.11 12.5 0.7 0.28 11.2 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) TAFII28 PF04719.14 EGO23028.1 - 6.5e-34 115.9 0.1 8e-34 115.6 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 EGO23028.1 - 0.00024 21.3 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Gemini_AL2 PF01440.16 EGO23032.1 - 0.015 15.8 0.4 0.023 15.1 0.4 1.5 1 1 0 1 1 1 0 Geminivirus AL2 protein EamA PF00892.20 EGO23033.1 - 2.1e-24 86.2 31.9 2e-14 53.9 9.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Trp_oprn_chp PF09534.10 EGO23033.1 - 0.49 10.2 4.6 0.22 11.3 0.2 2.4 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) YfhO PF09586.10 EGO23033.1 - 0.55 8.4 7.2 0.025 12.8 1.5 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF2070 PF09843.9 EGO23033.1 - 1 7.5 18.4 0.68 8.2 8.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) DUF3433 PF11915.8 EGO23035.1 - 7.3e-11 42.4 0.7 3.1e-10 40.4 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) SLATT_6 PF18169.1 EGO23035.1 - 0.21 11.2 0.0 0.46 10.1 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Hydrophobin PF01185.18 EGO23037.1 - 1.8e-11 44.5 0.6 2.2e-11 44.2 0.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Phage_holin_2_3 PF16080.5 EGO23037.1 - 0.62 9.9 2.1 0.84 9.4 2.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Sec_GG PF07549.14 EGO23038.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif SKG6 PF08693.10 EGO23039.1 - 0.00019 20.8 3.0 0.00019 20.8 3.0 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 EGO23039.1 - 0.0048 17.4 1.1 0.0048 17.4 1.1 2.7 3 0 0 3 3 3 1 Alphavirus glycoprotein J DUF3188 PF11384.8 EGO23039.1 - 0.013 15.2 1.5 0.028 14.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Phage_HK97_TLTM PF06120.11 EGO23039.1 - 0.05 12.8 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein FMN_bind_2 PF04299.12 EGO23039.1 - 0.093 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain Gram_pos_anchor PF00746.21 EGO23039.1 - 0.14 12.2 0.9 0.31 11.0 0.9 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Beta-APP PF03494.13 EGO23039.1 - 0.3 11.0 3.3 0.54 10.1 3.3 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Tubulin PF00091.25 EGO23040.1 - 3.2e-68 229.8 0.0 6.8e-68 228.7 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO23040.1 - 4.1e-42 143.3 0.1 6.5e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGO23040.1 - 5.2e-06 26.8 0.1 1.6e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGO23040.1 - 0.0021 17.3 0.0 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EGO23040.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain CPSase_L_D2 PF02786.17 EGO23041.1 - 7.7e-112 371.9 0.2 1.6e-79 266.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGO23041.1 - 3.2e-49 166.0 0.0 7.5e-49 164.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGO23041.1 - 6.5e-48 163.0 0.0 2.1e-46 158.1 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EGO23041.1 - 1.4e-45 154.9 0.0 2.9e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EGO23041.1 - 2.3e-42 144.2 0.1 8e-42 142.4 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGO23041.1 - 2.4e-32 112.2 0.0 6.5e-32 110.8 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 EGO23041.1 - 4.2e-19 68.9 0.1 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EGO23041.1 - 8e-19 67.6 0.0 3.5e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EGO23041.1 - 1.6e-14 53.9 0.1 8.8e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGO23041.1 - 2.9e-09 36.8 0.1 0.00029 20.6 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EGO23041.1 - 2.8e-06 27.2 0.1 0.0005 19.9 0.1 3.0 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 EGO23041.1 - 4.9e-05 23.4 0.1 0.08 13.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EGO23041.1 - 0.043 13.6 0.0 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EGO23041.1 - 0.065 12.7 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain SLATT_fungal PF18142.1 EGO23043.1 - 1.1e-31 109.3 0.1 1.8e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain FerA PF08165.11 EGO23043.1 - 0.045 13.7 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain SLD5_C PF16922.5 EGO23044.1 - 9.5e-08 32.1 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGO23044.1 - 4.1e-06 27.2 0.3 6.5e-06 26.6 0.3 1.5 1 0 0 1 1 1 1 GINS complex protein Cyt-b5 PF00173.28 EGO23045.1 - 3.9e-12 46.1 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR_4 PF15892.5 EGO23046.1 - 1.1e-46 159.4 0.0 1.6e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member MFS_1 PF07690.16 EGO23049.1 - 7.2e-42 143.6 60.1 1.6e-40 139.1 60.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily tRNA-synt_1b PF00579.25 EGO23050.1 - 1.8e-59 201.4 0.0 3.9e-59 200.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DnaJ PF00226.31 EGO23051.1 - 2.9e-26 91.4 1.0 2.9e-26 91.4 1.0 1.7 2 0 0 2 2 2 1 DnaJ domain MFS_1 PF07690.16 EGO23052.1 - 2.6e-39 135.2 67.3 2.6e-39 135.2 63.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily CENP-T_C PF15511.6 EGO23053.1 - 5.7e-07 29.6 0.0 9.5e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGO23053.1 - 7e-05 22.9 0.4 0.00015 21.9 0.1 1.7 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGO23053.1 - 0.00012 22.4 0.1 0.00021 21.6 0.1 1.6 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO23053.1 - 0.0011 19.2 0.3 0.0029 17.8 0.1 1.9 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO23053.1 - 0.0023 18.3 0.7 0.0043 17.4 0.1 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGO23053.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FtsJ PF01728.19 EGO23054.1 - 4e-43 147.6 0.0 5.1e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase TFIIIC_sub6 PF10419.9 EGO23055.1 - 3.6e-18 65.2 0.0 5.7e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Caskin-Pro-rich PF16907.5 EGO23055.1 - 0.21 12.1 9.9 1.6 9.3 0.9 2.3 1 1 1 2 2 2 0 Proline rich region of Caskin proteins DUF1884 PF08967.10 EGO23057.1 - 0.0018 18.5 1.6 0.0041 17.3 0.3 2.1 1 1 2 3 3 3 1 Domain of unknown function (DUF1884) Filament PF00038.21 EGO23057.1 - 0.024 14.2 21.2 0.15 11.6 21.3 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF745 PF05335.13 EGO23057.1 - 0.12 12.1 22.5 0.16 11.7 22.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Gastrin PF00918.17 EGO23057.1 - 5.2 8.1 9.7 7.3 7.6 9.6 1.4 1 1 0 1 1 1 0 Gastrin/cholecystokinin family DUF948 PF06103.11 EGO23057.1 - 6.7 7.0 12.5 4.1 7.7 4.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HSP70 PF00012.20 EGO23059.1 - 0.11 10.7 0.0 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein CCDC92 PF14916.6 EGO23060.1 - 9.9e-05 22.0 2.9 0.00022 20.9 2.9 1.5 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Septin PF00735.18 EGO23062.1 - 1.1e-112 376.0 0.3 1.5e-112 375.5 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGO23062.1 - 1.1e-07 31.9 0.1 4.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO23062.1 - 4.7e-07 29.9 0.1 3.9e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGO23062.1 - 2.9e-05 23.7 2.7 0.00032 20.3 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EGO23062.1 - 0.00021 21.5 0.1 0.00048 20.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGO23062.1 - 0.0007 20.0 0.0 0.0034 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO23062.1 - 0.0011 19.3 2.2 0.0044 17.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EGO23062.1 - 0.0034 17.1 1.2 0.15 11.8 0.2 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGO23062.1 - 0.0037 17.8 0.2 0.016 15.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 EGO23062.1 - 0.0053 16.0 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AIG1 PF04548.16 EGO23062.1 - 0.0061 15.9 0.1 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 EGO23062.1 - 0.0077 15.8 0.2 0.029 13.9 0.2 2.0 1 1 0 1 1 1 1 Ras family AAA_7 PF12775.7 EGO23062.1 - 0.011 15.2 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 EGO23062.1 - 0.02 14.7 1.0 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Pox_A32 PF04665.12 EGO23062.1 - 0.031 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 EGO23062.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EGO23062.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain GPW_gp25 PF04965.14 EGO23062.1 - 0.078 12.8 1.5 1.2 8.9 0.4 2.4 2 0 0 2 2 2 0 Gene 25-like lysozyme AAA_14 PF13173.6 EGO23062.1 - 0.079 13.0 0.4 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO23062.1 - 0.083 12.6 0.3 0.083 12.6 0.3 1.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGO23062.1 - 0.19 11.8 6.6 2.1 8.4 0.1 3.0 2 1 1 3 3 3 0 Dynamin family AAA_25 PF13481.6 EGO23062.1 - 0.26 10.8 1.8 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGO23062.1 - 0.36 11.3 2.2 1.1 9.7 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Atg14 PF10186.9 EGO23062.1 - 0.67 9.0 3.8 1.4 8.0 3.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 EGO23062.1 - 0.79 8.2 2.4 1.1 7.7 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FOXP-CC PF16159.5 EGO23062.1 - 1.6 9.4 4.7 0.52 11.0 0.9 2.2 2 1 0 2 2 1 0 FOXP coiled-coil domain SOGA PF11365.8 EGO23063.1 - 0.035 15.2 0.0 0.06 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein SOGA zf-CCHH PF10283.9 EGO23064.1 - 0.055 13.5 1.8 0.16 12.0 1.8 1.8 1 1 0 1 1 1 0 PBZ domain Pkinase_fungal PF17667.1 EGO23065.1 - 1.9e-06 26.9 0.0 3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO23065.1 - 2.6e-06 27.0 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGO23065.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO23065.1 - 0.0008 19.4 0.1 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGO23065.1 - 0.0061 15.9 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGO23065.1 - 0.0095 15.6 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 RIO1 family ubiquitin PF00240.23 EGO23066.1 - 0.092 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family NYD-SP28_assoc PF14775.6 EGO23067.1 - 0.01 15.9 0.3 0.023 14.8 0.0 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Retrotrans_gag PF03732.17 EGO23067.1 - 0.46 10.8 2.9 2.1 8.7 2.8 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein HA2 PF04408.23 EGO23069.1 - 2.7e-24 85.5 0.0 5.6e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO23069.1 - 4e-21 75.2 0.0 1.8e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO23069.1 - 1e-09 38.7 0.0 6e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO23069.1 - 9.9e-08 31.9 0.2 2.4e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO23069.1 - 9.4e-06 25.9 0.0 2.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGO23069.1 - 7.3e-05 22.5 0.1 0.00016 21.4 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGO23069.1 - 0.00025 21.4 0.1 0.00053 20.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO23069.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGO23069.1 - 0.016 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EGO23069.1 - 0.04 14.4 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO23069.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 EGO23069.1 - 0.079 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EGO23069.1 - 0.099 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 EGO23069.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Redoxin PF08534.10 EGO23070.1 - 1.1e-27 96.5 0.0 1.4e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGO23070.1 - 2.1e-11 43.8 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGO23070.1 - 0.047 14.0 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Proteasome PF00227.26 EGO23072.1 - 5e-30 104.4 0.1 5.9e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 EGO23072.1 - 0.028 14.3 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain MRG PF05712.13 EGO23073.1 - 4.1e-56 189.4 0.2 5.7e-56 189.0 0.2 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGO23073.1 - 6.3e-10 38.8 0.1 1.2e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EGO23073.1 - 0.065 13.1 0.4 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 EGO23074.1 - 1.5e-21 77.0 0.0 1.8e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23074.1 - 3.9e-09 36.2 0.0 4.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO23074.1 - 1.7e-08 33.6 0.1 2.3e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO23074.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hce2 PF14856.6 EGO23076.1 - 0.068 13.5 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Mago_nashi PF02792.14 EGO23077.1 - 7e-77 256.4 0.3 7.8e-77 256.2 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Ribosomal_S10 PF00338.22 EGO23078.1 - 2.7e-27 94.9 0.0 4.2e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e EnY2 PF10163.9 EGO23079.1 - 9.3e-25 86.8 0.1 1.1e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 OAR PF03826.17 EGO23079.1 - 0.087 12.7 0.8 0.16 11.8 0.8 1.4 1 0 0 1 1 1 0 OAR domain DUF4451 PF14616.6 EGO23080.1 - 7.5e-20 71.4 0.6 8.7e-20 71.1 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.24 EGO23081.1 - 2.7e-45 154.5 0.1 3.1e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL49_5 PF05702.11 EGO23081.1 - 0.37 10.9 2.5 1.3 9.2 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein Pkinase_fungal PF17667.1 EGO23082.1 - 4.1e-06 25.8 0.0 7.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO23082.1 - 5.6e-06 25.9 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGO23082.1 - 0.00023 20.6 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO23082.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO23082.1 - 0.021 14.4 0.0 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 EGO23082.1 - 0.033 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kv2channel PF03521.14 EGO23084.1 - 0.088 12.2 0.0 0.093 12.1 0.0 1.0 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel Aldedh PF00171.22 EGO23085.1 - 5.9e-123 410.8 0.0 7e-123 410.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO23085.1 - 1.5e-06 27.5 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Bcl-2_BAD PF10514.9 EGO23085.1 - 0.061 13.8 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD BAR_2 PF10455.9 EGO23086.1 - 5.3e-50 170.2 0.6 2.2e-49 168.2 0.6 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EGO23086.1 - 4.4e-16 59.3 1.6 5.8e-15 55.6 1.6 2.0 1 1 0 1 1 1 1 BAR domain Proteasome PF00227.26 EGO23087.1 - 2.9e-48 163.9 0.1 3.5e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGO23087.1 - 3.3e-14 52.0 2.4 3.3e-14 52.0 2.4 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 EGO23087.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SpoIIE PF07228.12 EGO23088.1 - 1.5e-05 25.0 0.0 4.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGO23088.1 - 8.4e-05 22.3 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGO23088.1 - 0.0054 16.4 0.0 0.0086 15.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Glycogen_syn PF05693.13 EGO23090.1 - 0 1090.2 0.0 0 1089.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 EGO23090.1 - 5.3e-07 29.6 0.4 1.2e-06 28.4 0.4 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EGO23090.1 - 1.4e-06 28.8 0.0 0.00089 19.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGO23090.1 - 1.8e-06 27.6 0.0 0.00029 20.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO23090.1 - 7.2e-05 22.8 0.8 0.00014 21.9 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGO23090.1 - 0.001 19.5 4.9 0.0032 17.9 4.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF92 PF01940.16 EGO23091.1 - 2.7e-71 239.8 3.7 3.5e-71 239.4 3.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 OTCace_N PF02729.21 EGO23092.1 - 5.4e-45 153.0 0.0 7.9e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EGO23092.1 - 1.7e-44 151.6 0.0 2.4e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain JmjN PF02375.17 EGO23093.1 - 1.8e-14 53.4 0.1 3.1e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 jmjN domain FHA PF00498.26 EGO23096.1 - 0.0016 18.8 0.1 0.0058 17.0 0.1 1.8 1 1 0 1 1 1 1 FHA domain TrkA_C PF02080.21 EGO23096.1 - 0.049 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-C domain NIBRIN_BRCT_II PF16508.5 EGO23097.1 - 0.0045 17.3 0.0 0.0081 16.5 0.0 1.4 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein CAP59_mtransfer PF11735.8 EGO23098.1 - 3.5e-37 128.4 0.0 6.5e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SLS PF14611.6 EGO23099.1 - 1.8e-11 44.3 0.0 2.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Retrotrans_gag PF03732.17 EGO23100.1 - 6.4e-05 23.1 0.5 6.4e-05 23.1 0.5 2.4 3 1 0 3 3 3 1 Retrotransposon gag protein OPT PF03169.15 EGO23107.1 - 3.4e-191 637.1 67.2 3.9e-191 636.9 67.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PAP_central PF04928.17 EGO23107.1 - 7.9 5.4 6.4 3 6.7 0.9 2.3 2 0 0 2 2 2 0 Poly(A) polymerase central domain FAS_N PF17828.1 EGO23108.1 - 0.021 14.8 0.3 0.023 14.7 0.3 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DUF5523 PF17661.1 EGO23110.1 - 0.0058 16.3 1.9 0.0077 15.9 1.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5523) ATP_bind_1 PF03029.17 EGO23111.1 - 8.9e-74 248.3 0.0 1.2e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGO23111.1 - 0.0001 21.9 0.0 0.018 14.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGO23111.1 - 0.00041 19.4 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EGO23111.1 - 0.00057 20.0 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGO23111.1 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO23111.1 - 0.0034 17.3 0.0 1.1 9.2 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 EGO23111.1 - 0.0097 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGO23111.1 - 0.018 14.5 0.0 0.083 12.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 EGO23111.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 EGO23111.1 - 0.05 13.2 0.1 5 6.7 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EGO23111.1 - 0.058 13.3 0.0 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EGO23111.1 - 0.081 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EGO23111.1 - 0.086 13.4 0.2 0.94 10.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EGO23111.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EGO23111.1 - 0.16 11.6 0.0 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GrpE PF01025.19 EGO23111.1 - 0.2 11.3 1.1 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 GrpE G-alpha PF00503.20 EGO23111.1 - 0.34 10.0 1.0 15 4.6 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pkinase PF00069.25 EGO23112.1 - 2.7e-77 259.7 0.0 3e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23112.1 - 1.9e-35 122.4 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO23112.1 - 2.3e-05 23.5 0.3 8.2e-05 21.7 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO23112.1 - 0.0026 17.7 0.1 0.015 15.2 0.1 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO23112.1 - 0.005 16.2 0.1 0.29 10.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGO23112.1 - 0.05 12.7 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 CH PF00307.31 EGO23112.1 - 0.14 12.4 0.1 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Calponin homology (CH) domain Kdo PF06293.14 EGO23112.1 - 0.15 11.4 0.3 0.41 10.0 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polysacc_lyase PF14099.6 EGO23114.1 - 0.077 12.8 0.0 0.43 10.4 0.0 2.0 1 1 1 2 2 2 0 Polysaccharide lyase adh_short_C2 PF13561.6 EGO23115.1 - 6.9e-63 212.3 8.3 9.2e-63 211.9 8.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO23115.1 - 4.4e-55 186.2 6.4 5.8e-55 185.8 6.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO23115.1 - 1.5e-12 47.8 3.5 2.6e-12 47.0 3.5 1.3 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 EGO23115.1 - 0.065 13.9 2.1 0.37 11.4 0.2 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF5012 PF16404.5 EGO23115.1 - 0.078 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) RVP_2 PF08284.11 EGO23117.1 - 0.00015 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO23117.1 - 0.00056 20.4 0.0 0.00084 19.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO23117.1 - 0.0021 18.7 0.0 0.003 18.2 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Siva PF05458.12 EGO23117.1 - 0.05 13.3 0.0 0.053 13.2 0.0 1.2 1 1 0 1 1 1 0 Cd27 binding protein (Siva) adh_short_C2 PF13561.6 EGO23118.1 - 3.1e-61 206.9 6.8 4.1e-61 206.5 6.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO23118.1 - 1.2e-52 178.2 5.7 1.6e-52 177.9 5.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO23118.1 - 2.3e-11 44.0 3.7 3.9e-11 43.2 3.7 1.3 1 0 0 1 1 1 1 KR domain Pro_CA PF00484.19 EGO23119.1 - 1.1e-08 35.5 0.1 5.1e-08 33.4 0.1 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 EGO23120.1 - 2.5e-15 57.1 0.0 3.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase p450 PF00067.22 EGO23121.1 - 8.8e-69 232.4 0.0 1e-68 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I10 PF12559.8 EGO23121.1 - 5.8e-05 23.3 0.1 0.0021 18.3 0.0 2.8 1 1 1 2 2 2 1 Serine endopeptidase inhibitors RVP_2 PF08284.11 EGO23122.1 - 3.3e-06 26.9 0.1 4.5e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO23122.1 - 0.0024 18.4 0.0 0.0038 17.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO23122.1 - 0.034 14.8 0.0 0.052 14.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Rol_Rep_N PF18106.1 EGO23122.1 - 0.063 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain Ank_2 PF12796.7 EGO23124.1 - 1.4e-08 35.2 0.2 3.9e-08 33.8 0.2 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO23124.1 - 3.9e-07 30.2 0.7 3.3e-06 27.3 0.2 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO23124.1 - 7.2e-06 26.5 0.1 0.0048 17.4 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO23124.1 - 7.2e-05 22.9 0.1 0.053 14.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGO23124.1 - 0.0035 17.7 1.5 0.03 14.8 0.2 2.8 3 0 0 3 3 3 1 Ankyrin repeat Sec7_N PF12783.7 EGO23125.1 - 3.4e-45 153.8 5.8 6.9e-45 152.8 0.8 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EGO23125.1 - 1.2e-44 152.1 1.5 5.7e-44 149.9 1.5 2.3 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EGO23125.1 - 8.2e-37 126.8 7.1 1.1e-23 83.4 2.9 3.8 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 EGO23125.1 - 7.4e-06 25.7 0.1 0.00035 20.4 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 EGO23125.1 - 0.017 15.3 0.1 1.1 9.4 0.0 3.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 BLM10_mid PF16507.5 EGO23125.1 - 0.1 11.3 0.5 0.3 9.7 0.2 2.0 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region zf-CCHC PF00098.23 EGO23127.1 - 2.2e-07 30.6 4.0 3.9e-07 29.8 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF5637 PF18687.1 EGO23127.1 - 0.14 12.2 2.4 0.28 11.2 2.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5637) zf-C4H2 PF10146.9 EGO23127.1 - 0.33 11.2 8.3 0.6 10.4 6.6 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein KDZ PF18758.1 EGO23128.1 - 5.2e-54 183.2 0.0 5e-52 176.7 0.0 2.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGO23128.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases AlaDh_PNT_C PF01262.21 EGO23130.1 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tet_JBP PF12851.7 EGO23131.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily zf-RING_2 PF13639.6 EGO23132.1 - 3.8e-09 36.7 11.7 5.7e-09 36.2 11.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO23132.1 - 7.2e-09 35.4 10.6 1.1e-08 34.8 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO23132.1 - 2.7e-08 33.5 6.8 3.7e-08 33.1 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO23132.1 - 2.8e-08 33.5 10.0 4.3e-08 32.9 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO23132.1 - 1.6e-06 28.0 6.9 2.9e-06 27.2 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGO23132.1 - 1.2e-05 25.5 9.9 3.5e-05 24.0 9.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGO23132.1 - 3.7e-05 23.6 9.6 5.6e-05 23.0 9.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO23132.1 - 0.00015 21.5 7.4 0.00026 20.8 7.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGO23132.1 - 0.0023 18.0 10.1 0.0042 17.2 10.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Siva PF05458.12 EGO23132.1 - 0.0096 15.6 3.4 0.015 15.0 3.4 1.2 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-C2HCIx2C PF10782.9 EGO23132.1 - 0.012 15.5 1.1 0.021 14.8 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger LuxT_C PF18285.1 EGO23132.1 - 0.058 13.9 0.0 0.093 13.3 0.0 1.3 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain zf-RING_4 PF14570.6 EGO23132.1 - 0.11 12.3 6.4 0.25 11.2 6.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGO23132.1 - 0.12 12.5 5.1 0.47 10.5 5.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rhodopsin_N PF10413.9 EGO23132.1 - 0.17 11.7 1.0 0.29 11.0 1.0 1.3 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin zf-P11 PF03854.14 EGO23132.1 - 0.24 11.1 7.0 0.73 9.5 7.0 1.8 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 EGO23132.1 - 0.5 10.2 13.3 0.064 13.0 9.1 1.7 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 EGO23132.1 - 0.53 10.4 4.5 0.97 9.5 4.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 EGO23132.1 - 0.66 9.9 4.7 1.3 9.0 4.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 EGO23132.1 - 5.4 7.3 9.5 10 6.5 7.9 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Homeodomain PF00046.29 EGO23134.1 - 6.2e-15 54.8 1.7 1.2e-14 53.9 1.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGO23134.1 - 0.0089 15.9 1.8 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Bromodomain PF00439.25 EGO23136.1 - 2.7e-11 43.4 0.0 2.9e-07 30.5 0.0 2.6 1 1 1 2 2 2 2 Bromodomain SipA_VBS PF17985.1 EGO23136.1 - 0.16 11.9 0.2 16 5.6 0.0 2.7 2 0 0 2 2 2 0 SipA vinculin binding site MutL_C PF08676.11 EGO23137.1 - 3.6e-27 95.0 0.3 6.4e-27 94.1 0.3 1.4 1 1 0 1 1 1 1 MutL C terminal dimerisation domain G-alpha PF00503.20 EGO23138.1 - 3e-101 339.1 0.0 3.6e-101 338.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO23138.1 - 5.5e-14 52.0 0.1 4.4e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 EGO23138.1 - 0.00092 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EGO23138.1 - 0.0011 18.3 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO23138.1 - 0.0012 19.0 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGO23138.1 - 0.022 14.1 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 EGO23138.1 - 0.03 14.2 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGO23138.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EGO23138.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NEMO PF11577.8 EGO23138.1 - 0.39 10.7 4.8 0.82 9.7 4.8 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Pyr_redox_2 PF07992.14 EGO23139.1 - 3.1e-24 85.7 0.0 2.2e-23 82.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO23139.1 - 9.5e-13 48.5 0.7 2.3e-11 44.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO23139.1 - 0.0015 17.8 0.0 0.0055 16.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO23139.1 - 0.0045 16.2 0.0 0.01 15.0 0.0 1.3 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGO23139.1 - 0.015 14.9 0.2 4 6.9 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO23139.1 - 0.027 14.5 1.3 0.16 12.0 0.0 2.4 2 1 1 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EGO23139.1 - 0.072 13.4 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 EGO23139.1 - 0.083 11.7 0.6 0.82 8.4 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 EGO23139.1 - 0.18 12.1 1.1 5 7.4 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO23139.1 - 0.19 10.4 0.3 0.83 8.3 0.0 2.1 2 1 1 3 3 3 0 HI0933-like protein ThiF PF00899.21 EGO23139.1 - 0.39 10.0 0.0 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 ThiF family Glyco_hydro_28 PF00295.17 EGO23140.1 - 9.9e-58 195.7 16.9 1.2e-57 195.4 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1565 PF07602.11 EGO23140.1 - 0.00027 20.4 7.5 0.00031 20.2 5.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) AMP-binding PF00501.28 EGO23141.1 - 1.2e-59 202.1 0.0 1.6e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EGO23141.1 - 1.3e-29 104.0 0.2 5e-29 102.0 0.1 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EGO23141.1 - 5.2e-10 39.5 0.0 1.6e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EGO23141.1 - 0.0023 18.6 0.1 0.0071 17.0 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO23141.1 - 0.021 14.1 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO23141.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold ADH_N PF08240.12 EGO23142.1 - 6.3e-10 38.9 0.0 6.3e-08 32.5 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO23142.1 - 1e-08 35.2 0.1 4.8e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO23142.1 - 0.006 17.6 0.0 0.012 16.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGO23142.1 - 0.078 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Aminotran_1_2 PF00155.21 EGO23143.1 - 1e-21 77.6 0.0 1.4e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGO23143.1 - 4.9e-05 22.3 0.0 7.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase FAS_meander PF17951.1 EGO23143.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Aminotran_1_2 PF00155.21 EGO23144.1 - 1.7e-21 76.8 0.0 2.3e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGO23144.1 - 5.4e-05 22.2 0.0 8.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase FAS_meander PF17951.1 EGO23144.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain TFIIB PF00382.19 EGO23148.1 - 3.6e-38 129.5 0.7 2.8e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGO23148.1 - 6.3e-22 77.8 16.4 1.7e-20 73.3 5.8 3.3 2 1 0 2 2 2 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGO23148.1 - 5.4e-09 35.4 9.9 3.7e-08 32.7 4.5 2.3 1 1 1 2 2 2 2 TFIIB zinc-binding Cyclin_N PF00134.23 EGO23148.1 - 0.00038 20.2 0.9 0.32 10.7 0.3 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 EGO23148.1 - 0.0069 16.4 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon DUF4145 PF13643.6 EGO23148.1 - 0.1 12.8 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) zf-RRN7 PF11781.8 EGO23148.1 - 0.12 12.1 2.2 0.22 11.3 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Plavaka PF18759.1 EGO23151.1 - 3e-20 72.7 6.1 1.3e-19 70.6 6.1 1.9 1 1 0 1 1 1 1 Plavaka transposase Aldo_ket_red PF00248.21 EGO23154.1 - 6.9e-47 160.1 0.0 1.5e-38 132.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family HAMP PF00672.25 EGO23156.1 - 1e-41 141.1 20.1 8.3e-08 32.5 0.1 8.7 8 0 0 8 8 8 7 HAMP domain HATPase_c PF02518.26 EGO23156.1 - 2.1e-29 102.3 0.1 6.5e-29 100.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO23156.1 - 1e-22 80.4 0.1 4e-22 78.5 0.1 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGO23156.1 - 3.3e-17 62.3 1.9 1.2e-16 60.5 1.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 EGO23156.1 - 2.5e-05 24.0 0.4 1.3 8.6 0.0 4.2 2 1 1 4 4 4 1 Domain of unknown function (DUF4795) DUF3829 PF12889.7 EGO23156.1 - 0.55 9.7 2.2 11 5.4 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 EGO23156.1 - 0.86 9.7 4.2 80 3.4 0.0 4.7 5 0 0 5 5 5 0 Stage III sporulation protein D T4SS PF07996.11 EGO23156.1 - 1.1 9.6 9.7 4.1 7.7 0.4 3.5 3 1 0 3 3 3 0 Type IV secretion system proteins Fungal_trans PF04082.18 EGO23157.1 - 7.4e-18 64.5 0.3 1.3e-17 63.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nup84_Nup100 PF04121.13 EGO23158.1 - 6.4e-169 563.5 0.0 7.8e-169 563.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.14 EGO23158.1 - 0.0048 15.4 0.0 0.0096 14.4 0.0 1.4 1 0 0 1 1 1 1 Nup93/Nic96 TPR_14 PF13428.6 EGO23158.1 - 0.098 13.5 1.5 1.8 9.6 0.1 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PLDc PF00614.22 EGO23159.1 - 2.8e-18 65.3 1.7 2.1e-09 37.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGO23159.1 - 3.4e-16 59.3 0.0 8.9e-07 28.9 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Pro_isomerase PF00160.21 EGO23160.1 - 2e-51 174.4 0.1 2.3e-51 174.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMC_oxred_N PF00732.19 EGO23161.1 - 4.4e-65 220.0 0.0 6.4e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO23161.1 - 1e-33 116.9 0.0 2.5e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO23161.1 - 3.8e-05 22.9 0.1 6.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO23161.1 - 0.00086 18.5 0.8 0.74 8.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EGO23161.1 - 0.0015 17.9 0.2 0.004 16.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EGO23161.1 - 0.16 10.8 0.2 0.27 10.0 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EGO23161.1 - 0.21 10.2 0.6 0.36 9.5 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein PIP5K PF01504.18 EGO23162.1 - 6.6e-45 153.5 2.1 2.5e-36 125.3 0.0 2.7 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase GSDH PF07995.11 EGO23162.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase adh_short PF00106.25 EGO23163.1 - 3.9e-22 78.7 0.2 1.1e-21 77.1 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23163.1 - 4.6e-20 72.2 0.5 2.7e-19 69.7 0.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 EGO23163.1 - 0.0092 15.9 0.1 0.038 13.9 0.1 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 EGO23163.1 - 0.058 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_28 PF00295.17 EGO23165.1 - 4.7e-56 190.2 13.4 6.5e-56 189.7 13.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 EGO23166.1 - 1.3e-49 169.0 11.8 2.1e-49 168.4 11.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Aa_trans PF01490.18 EGO23167.1 - 2.4e-28 99.0 33.8 4e-28 98.3 33.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase_fungal PF17667.1 EGO23169.1 - 2.3e-12 46.4 0.0 3.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO23169.1 - 0.00035 20.0 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGO23170.1 - 3.5e-10 39.2 0.0 3.5e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Septin PF00735.18 EGO23173.1 - 0.063 12.5 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 Septin DUF4349 PF14257.6 EGO23174.1 - 0.0047 16.4 2.2 0.44 10.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4349) bZIP_1 PF00170.21 EGO23174.1 - 0.077 13.1 2.4 0.16 12.0 1.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor Bap31_Bap29_C PF18035.1 EGO23174.1 - 0.2 11.7 4.4 0.27 11.3 0.5 2.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Csm1_N PF18504.1 EGO23174.1 - 5.2 7.5 9.5 0.51 10.7 2.0 2.7 2 1 0 2 2 2 0 Csm1 N-terminal domain Ax_dynein_light PF10211.9 EGO23174.1 - 6.3 6.7 10.9 0.21 11.5 2.8 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DDE_1 PF03184.19 EGO23175.1 - 5.9e-14 52.1 0.0 9.4e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO23175.1 - 0.0023 17.7 0.1 0.0083 15.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease SPC12 PF06645.13 EGO23176.1 - 1.2e-26 92.6 0.6 1.4e-26 92.4 0.6 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Pkinase PF00069.25 EGO23177.1 - 1.5e-65 221.2 0.0 1.9e-64 217.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23177.1 - 3.8e-36 124.7 0.0 3.2e-35 121.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGO23177.1 - 4.3e-16 58.4 0.1 7.4e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EGO23177.1 - 3.3e-06 26.6 0.2 5.5e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO23177.1 - 2.5e-05 24.3 0.6 0.00092 19.2 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO23177.1 - 0.00021 20.7 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO23177.1 - 0.00035 19.6 0.0 0.00054 19.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 EGO23177.1 - 0.023 14.3 0.4 0.042 13.5 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Aa_trans PF01490.18 EGO23179.1 - 3e-35 121.7 37.1 3.4e-35 121.5 37.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TauD PF02668.16 EGO23181.1 - 2.6e-52 178.3 0.2 3.3e-52 177.9 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Phage_30_3 PF08010.11 EGO23181.1 - 0.07 12.9 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 UL16 PF17622.2 EGO23181.1 - 0.18 11.5 0.2 0.81 9.3 0.0 2.0 2 0 0 2 2 2 0 Viral unique long protein 16 UPF0767 PF15990.5 EGO23182.1 - 0.14 12.3 0.1 0.21 11.7 0.1 1.3 1 1 0 1 1 1 0 UPF0767 family DUF455 PF04305.14 EGO23184.1 - 9.5e-94 313.6 0.0 1.1e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) WD40 PF00400.32 EGO23186.1 - 2.8e-48 160.9 27.4 5.2e-12 46.1 0.0 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO23186.1 - 1.3e-23 83.1 0.2 1.3e-05 25.4 0.0 6.5 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EGO23186.1 - 3e-12 46.8 0.0 6.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 EGO23186.1 - 3.3e-08 33.2 0.1 1.3e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 WD40-like domain AAA_16 PF13191.6 EGO23186.1 - 3.9e-07 30.6 0.1 1e-06 29.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 EGO23186.1 - 5.7e-05 22.2 6.2 1.4 7.8 0.3 5.6 2 1 5 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGO23186.1 - 0.0002 21.0 0.6 0.013 15.1 0.2 2.5 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 EGO23186.1 - 0.00031 19.5 0.5 0.34 9.5 0.0 3.2 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO23186.1 - 0.00036 19.4 0.3 0.81 8.4 0.0 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 EGO23186.1 - 0.00086 17.9 0.6 0.11 11.0 0.1 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain AAA_22 PF13401.6 EGO23186.1 - 0.0086 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EGO23186.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 EGO23186.1 - 0.024 13.9 0.1 0.053 12.7 0.1 1.4 1 1 0 1 1 1 0 KAP family P-loop domain RAB3GAP2_N PF14655.6 EGO23186.1 - 0.025 13.9 0.0 5.2 6.2 0.1 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ATPase_2 PF01637.18 EGO23186.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Frtz PF11768.8 EGO23186.1 - 0.065 11.5 0.2 1 7.6 0.0 2.4 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz NB-ARC PF00931.22 EGO23186.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain PD40 PF07676.12 EGO23186.1 - 1.2 9.2 3.0 75 3.4 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Retrotrans_gag PF03732.17 EGO23188.1 - 3.2e-06 27.3 0.3 8e-06 26.0 0.1 1.8 1 1 1 2 2 2 1 Retrotransposon gag protein p450 PF00067.22 EGO23189.1 - 1.2e-66 225.3 0.0 1.9e-64 218.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23190.1 - 1.3e-69 235.2 0.0 1.4e-50 172.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 F-box-like PF12937.7 EGO23191.1 - 7.4e-09 35.4 1.8 1.4e-08 34.5 0.6 2.2 2 0 0 2 2 2 1 F-box-like TPR_8 PF13181.6 EGO23192.1 - 1.8e-05 24.6 0.4 1.5 9.3 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO23192.1 - 2.2e-05 24.9 10.6 0.081 13.8 0.0 6.1 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO23192.1 - 3.6e-05 23.6 14.8 0.42 10.9 0.0 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGO23192.1 - 0.0022 18.4 2.2 3 8.7 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO23192.1 - 0.004 17.4 0.3 18 5.6 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGO23192.1 - 0.0041 17.4 1.9 42 4.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGO23192.1 - 0.015 15.3 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.6 EGO23192.1 - 0.038 14.0 2.7 13 6.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO23192.1 - 0.038 13.3 1.0 2.2 7.5 0.0 3.6 5 1 0 5 5 5 0 MalT-like TPR region TPR_19 PF14559.6 EGO23192.1 - 0.043 14.3 2.7 39 4.9 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO23192.1 - 0.082 12.8 8.5 13 5.8 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO23192.1 - 0.098 12.4 10.4 2.1 8.1 0.1 5.2 6 0 0 6 6 6 0 TPR repeat Yos9_DD PF17880.1 EGO23192.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Yos9 dimerzation domain CAP_N PF01213.19 EGO23192.1 - 5.3 6.4 8.0 0.25 10.8 1.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TPR_1 PF00515.28 EGO23194.1 - 5.7e-38 127.2 7.7 0.00029 20.5 0.0 11.1 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGO23194.1 - 2.4e-36 120.9 12.8 3.3e-05 23.6 0.0 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGO23194.1 - 4.8e-24 83.8 8.3 1.7e-08 34.0 0.0 6.8 5 3 1 6 6 6 4 TPR repeat TPR_8 PF13181.6 EGO23194.1 - 7e-23 78.9 7.4 0.00016 21.6 0.0 9.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO23194.1 - 2e-21 76.0 14.3 4.9e-07 29.9 0.0 7.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO23194.1 - 7.4e-18 64.9 15.4 1.6e-06 28.6 0.0 6.8 5 1 3 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGO23194.1 - 2.4e-17 63.2 12.8 0.00011 22.6 0.1 6.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGO23194.1 - 4.5e-17 60.8 8.2 0.00042 20.1 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGO23194.1 - 3.5e-15 55.2 4.0 2.6e-05 24.3 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO23194.1 - 2.5e-14 52.7 15.4 3.9e-05 24.1 0.0 8.5 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO23194.1 - 3.7e-11 43.0 10.3 0.0025 17.9 0.0 6.1 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO23194.1 - 4.8e-11 42.6 7.2 0.0001 21.8 0.7 3.6 3 1 1 4 4 4 3 MalT-like TPR region TPR_6 PF13174.6 EGO23194.1 - 4e-10 39.7 7.3 0.092 13.4 0.0 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO23194.1 - 3e-09 37.0 4.6 0.0013 19.0 0.0 4.8 3 1 2 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGO23194.1 - 8.8e-06 25.4 18.2 0.18 11.7 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 EGO23194.1 - 3.8e-05 23.5 12.3 0.037 13.7 0.1 5.3 6 1 1 7 7 6 1 Tetratricopeptide repeat-like domain NARP1 PF12569.8 EGO23194.1 - 0.0021 17.1 0.1 0.0021 17.1 0.1 3.0 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 MAS20 PF02064.15 EGO23194.1 - 0.0028 17.7 9.3 0.062 13.4 1.4 4.3 4 1 1 5 5 4 1 MAS20 protein import receptor DUF3856 PF12968.7 EGO23194.1 - 0.0042 17.2 7.4 4.6 7.3 0.0 5.6 3 2 2 5 5 5 1 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 EGO23194.1 - 0.0062 16.6 1.8 0.38 10.9 0.0 3.5 2 1 1 3 3 2 1 Anaphase-promoting complex subunit 5 PknG_TPR PF16918.5 EGO23194.1 - 0.0065 15.2 1.1 0.2 10.4 0.0 2.8 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 EGO23194.1 - 0.017 15.4 8.1 0.87 10.0 0.1 5.5 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGO23194.1 - 0.022 14.0 8.8 0.031 13.5 0.1 3.9 2 2 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO23194.1 - 0.13 12.4 2.0 14 5.8 0.0 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 EGO23194.1 - 0.21 12.3 1.6 9.7 7.0 0.0 4.3 5 0 0 5 5 3 0 Sel1 repeat SHNi-TPR PF10516.9 EGO23194.1 - 0.25 10.8 6.0 6.5 6.3 0.2 4.2 4 0 0 4 4 4 0 SHNi-TPR Myco_arth_vir_N PF09610.10 EGO23194.1 - 0.26 11.4 0.7 0.77 9.9 0.7 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF627 PF04781.12 EGO23194.1 - 0.29 11.1 4.0 0.33 11.0 0.1 3.2 4 1 1 5 5 4 0 Protein of unknown function (DUF627) MIT PF04212.18 EGO23194.1 - 0.36 10.9 11.6 4.5 7.4 0.5 5.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Trep_dent_lipo PF09710.10 EGO23194.1 - 4.7 6.0 5.7 4.5 6.1 3.4 2.1 1 1 0 2 2 2 0 Treponema clustered lipoprotein (Trep_dent_lipo) Diphthamide_syn PF01866.17 EGO23195.1 - 7.7e-102 340.8 0.0 9.7e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein EOS1 PF12326.8 EGO23196.1 - 6.1e-29 101.2 3.9 8.6e-20 71.4 0.4 2.5 2 0 0 2 2 2 2 N-glycosylation protein GTP1_OBG PF01018.22 EGO23198.1 - 0.0032 17.1 6.8 0.0032 17.1 6.8 2.4 2 1 1 3 3 3 1 GTP1/OBG DUF3150 PF11348.8 EGO23198.1 - 0.011 15.0 0.0 0.031 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) DUF812 PF05667.11 EGO23198.1 - 0.017 14.0 1.1 0.026 13.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) G2BR PF18442.1 EGO23199.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) SOG2 PF10428.9 EGO23199.1 - 4.8 6.3 7.8 5.8 6.0 7.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein FAD_binding_4 PF01565.23 EGO23200.1 - 5.9e-21 74.7 3.0 1.1e-20 73.8 3.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO23200.1 - 5.8e-06 26.3 0.1 5.8e-06 26.3 0.1 2.7 3 0 0 3 3 3 1 Berberine and berberine like BSP PF04450.12 EGO23201.1 - 1.6e-62 211.0 0.0 1.8e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 EGO23201.1 - 0.061 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 SprT-like family 2OG-FeII_Oxy_2 PF13532.6 EGO23202.1 - 8.7e-26 91.3 0.0 1.1e-25 91.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rad60-SLD PF11976.8 EGO23203.1 - 9.5e-23 79.8 0.3 1.3e-22 79.4 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGO23203.1 - 9e-13 47.8 0.1 1.2e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family FAM222A PF15258.6 EGO23203.1 - 0.17 11.0 0.4 0.22 10.6 0.4 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Pkinase PF00069.25 EGO23205.1 - 1.6e-12 47.3 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23205.1 - 5.6e-09 35.6 0.0 7e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGO23205.1 - 0.0048 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain PH_5 PF15405.6 EGO23205.1 - 0.058 13.5 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain p450 PF00067.22 EGO23206.1 - 4.2e-61 207.1 0.0 7.6e-61 206.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 EGO23206.1 - 0.021 14.8 1.8 2.4 8.1 0.6 2.5 2 0 0 2 2 2 0 Reticulon RicinB_lectin_2 PF14200.6 EGO23207.1 - 6.1e-17 62.1 1.7 2.2e-09 37.9 0.1 3.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 EGO23207.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 FRG1-like domain DUF2138 PF09909.9 EGO23209.1 - 0.079 11.3 0.0 0.081 11.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Glyco_hydro_30 PF02055.16 EGO23210.1 - 7.5e-21 74.5 0.3 1.1e-20 74.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EGO23210.1 - 2.7e-14 53.1 0.2 4e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EGO23210.1 - 0.0081 15.8 0.0 4 6.9 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 EGO23210.1 - 0.016 14.8 0.2 0.029 13.9 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Trp_oprn_chp PF09534.10 EGO23213.1 - 0.03 14.1 0.3 0.05 13.4 0.3 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zf-CCHC_3 PF13917.6 EGO23215.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO23215.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO23215.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO23215.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Thiolase_N PF00108.23 EGO23217.1 - 2.3e-64 217.3 0.3 3.1e-64 216.8 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO23217.1 - 7.7e-46 154.7 0.2 1.9e-45 153.5 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EGO23217.1 - 0.00028 20.7 0.1 0.019 14.8 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGO23217.1 - 0.0011 18.6 0.2 0.0032 17.1 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EGO23217.1 - 0.093 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Asp_protease_2 PF13650.6 EGO23218.1 - 0.00083 20.0 0.0 0.0023 18.5 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO23218.1 - 0.0017 18.8 0.0 0.0054 17.3 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO23218.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 EGO23221.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO23221.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO23221.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO23221.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Tropomyosin_1 PF12718.7 EGO23223.1 - 0.36 11.0 2.3 0.89 9.7 2.3 1.6 1 1 0 1 1 1 0 Tropomyosin like G-gamma PF00631.22 EGO23224.1 - 0.019 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 GGL domain THDPS_N_2 PF14805.6 EGO23226.1 - 0.035 14.3 0.2 0.047 13.9 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal p450 PF00067.22 EGO23228.1 - 2.1e-69 234.5 0.0 2.6e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.6 EGO23229.1 - 1.5e-29 102.0 3.2 1.6e-11 44.5 0.0 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO23229.1 - 2.8e-27 94.4 1.4 5.3e-09 36.2 0.0 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO23229.1 - 4.7e-27 94.4 0.2 4.2e-13 49.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO23229.1 - 1.2e-26 89.8 0.1 3.6e-07 30.0 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGO23229.1 - 8.6e-23 79.7 0.3 8e-07 29.2 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Nitro_FeMo-Co PF02579.17 EGO23229.1 - 0.0024 18.1 0.2 2.3 8.6 0.0 2.7 1 1 2 3 3 3 2 Dinitrogenase iron-molybdenum cofactor AHH PF14412.6 EGO23229.1 - 0.08 13.0 0.2 13 5.9 0.0 2.2 1 1 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH OCD_Mu_crystall PF02423.15 EGO23230.1 - 4.9e-33 114.4 1.0 3e-20 72.4 0.2 2.3 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family p450 PF00067.22 EGO23231.1 - 1.2e-11 44.0 0.0 1.3e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.15 EGO23231.1 - 0.027 14.1 1.9 0.33 10.8 0.9 2.5 2 1 0 2 2 2 0 Ataxin-2 C-terminal region Presenilin PF01080.17 EGO23232.1 - 10 4.8 6.4 9.8 4.8 6.4 1.0 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 EGO23234.1 - 6.5e-58 196.6 0.0 7.8e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DRY_EERY PF09750.9 EGO23235.1 - 0.0031 17.8 6.6 0.011 16.1 6.6 1.9 1 1 0 1 1 1 1 Alternative splicing regulator Surp PF01805.20 EGO23235.1 - 0.083 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Surp module Peptidase_M48_N PF16491.5 EGO23236.1 - 6.6e-62 208.6 4.4 6.6e-62 208.6 4.4 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGO23236.1 - 1.1e-36 126.4 0.1 2.4e-36 125.4 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EGO23236.1 - 0.0033 16.7 0.2 0.0062 15.8 0.2 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 EGO23236.1 - 0.049 13.5 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 SprT-like family AMP-binding PF00501.28 EGO23238.1 - 2.2e-74 250.6 0.0 3.1e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGO23238.1 - 1.1e-13 50.7 0.1 2.5e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Condensation domain Methyltransf_25 PF13649.6 EGO23238.1 - 2.7e-11 44.0 0.0 1e-10 42.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO23238.1 - 7.4e-10 39.5 0.0 3.9e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGO23238.1 - 1.1e-09 38.5 0.0 4.7e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGO23238.1 - 1.7e-09 38.2 0.0 8.2e-09 36.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23238.1 - 2.8e-09 36.9 0.1 7.1e-08 32.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain AMP-binding_C PF13193.6 EGO23238.1 - 2.2e-08 35.0 0.0 0.0021 19.0 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 EGO23238.1 - 1.2e-07 31.7 0.0 3.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGO23238.1 - 3.2e-06 26.9 0.0 8.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EGO23238.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EGO23238.1 - 2.7e-05 23.8 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 EGO23238.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EGO23238.1 - 0.019 14.6 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 EGO23238.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 EGO23238.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_S28 PF05577.12 EGO23240.1 - 0.013 14.3 0.0 0.35 9.6 0.0 2.0 1 1 1 2 2 2 0 Serine carboxypeptidase S28 ATG22 PF11700.8 EGO23241.1 - 9.5e-153 509.3 6.5 1.2e-152 508.9 6.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGO23241.1 - 2.4e-11 43.2 41.2 5.4e-06 25.6 4.1 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily p450 PF00067.22 EGO23242.1 - 4.1e-69 233.5 0.0 5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4176 PF13780.6 EGO23242.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) Avidin PF01382.17 EGO23242.1 - 0.15 12.5 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 Avidin family Rad60-SLD PF11976.8 EGO23243.1 - 6.1e-10 38.8 0.1 8.2e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGO23243.1 - 1.3e-07 31.3 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.24 EGO23243.1 - 0.021 14.8 0.7 0.03 14.3 0.0 1.6 2 0 0 2 2 2 0 PB1 domain Rad60-SLD PF11976.8 EGO23244.1 - 7.6e-12 44.9 0.0 9.4e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGO23244.1 - 1.3e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EGO23244.1 - 0.00076 19.6 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 TUG ubiquitin-like domain DUF2280 PF10045.9 EGO23244.1 - 0.075 13.3 0.0 0.084 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) F-box-like PF12937.7 EGO23245.1 - 0.00039 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like Prenyltrans PF00432.21 EGO23246.1 - 5.6e-31 106.0 13.5 4.6e-07 29.5 0.5 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGO23246.1 - 0.074 12.1 0.0 4.5 6.3 0.0 2.5 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain Sacchrp_dh_C PF16653.5 EGO23247.1 - 4e-89 299.2 0.0 7.9e-89 298.3 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 EGO23247.1 - 1.1e-67 227.1 0.0 2.3e-67 226.1 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGO23247.1 - 6.5e-25 86.8 0.8 1.3e-24 85.8 0.1 2.0 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 EGO23247.1 - 3.7e-23 82.2 1.7 1.6e-22 80.2 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 EGO23247.1 - 1.4e-06 28.9 0.0 0.0001 22.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Shikimate_DH PF01488.20 EGO23247.1 - 2.1e-06 27.8 0.0 2e-05 24.6 0.0 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EGO23247.1 - 0.0032 17.4 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 EGO23247.1 - 0.0035 18.1 0.1 0.037 14.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGO23247.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HMG_box PF00505.19 EGO23249.1 - 1.4e-15 57.4 2.8 2.4e-15 56.7 2.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO23249.1 - 1.3e-06 28.9 0.8 2e-06 28.3 0.8 1.3 1 0 0 1 1 1 1 HMG-box domain Peptidase_M61 PF05299.12 EGO23249.1 - 0.054 13.9 0.0 0.076 13.4 0.0 1.2 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Sugar_tr PF00083.24 EGO23252.1 - 1.2e-115 386.9 23.0 1.4e-115 386.7 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO23252.1 - 1.4e-22 80.1 30.5 1.4e-22 80.1 30.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Flavi_NS4A PF01350.17 EGO23252.1 - 0.99 9.3 5.1 3.3 7.7 0.0 3.1 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A Aldo_ket_red PF00248.21 EGO23253.1 - 3.2e-38 131.6 0.0 8.5e-37 126.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_25 PF13649.6 EGO23253.1 - 0.021 15.5 0.0 0.055 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGO23253.1 - 0.052 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EGO23253.1 - 0.057 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGO23253.1 - 0.22 11.2 0.0 0.53 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aldo_ket_red PF00248.21 EGO23254.1 - 2.8e-41 141.6 0.0 3.1e-38 131.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family AMP-binding PF00501.28 EGO23255.1 - 7.9e-61 205.9 0.0 1.8e-44 152.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 EGO23255.1 - 1.1e-13 51.4 0.1 4.6e-12 46.1 0.0 3.1 3 0 0 3 3 3 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EGO23255.1 - 2.9e-11 43.9 0.0 2.1e-10 41.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Condensation PF00668.20 EGO23255.1 - 8.8e-11 41.1 0.1 2.9e-10 39.4 0.1 1.8 1 1 0 1 1 1 1 Condensation domain Methyltransf_11 PF08241.12 EGO23255.1 - 2.2e-10 41.0 0.0 2.4e-09 37.7 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23255.1 - 7.3e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO23255.1 - 1.1e-08 35.7 0.0 3.5e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 EGO23255.1 - 1.4e-08 35.6 0.9 0.0003 21.7 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 EGO23255.1 - 1.8e-07 31.1 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO23255.1 - 0.00082 19.0 0.0 0.0024 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.8 EGO23255.1 - 0.0024 17.1 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 EGO23255.1 - 0.0083 15.7 0.1 0.023 14.3 0.1 1.7 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 EGO23255.1 - 0.0084 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.18 EGO23255.1 - 0.016 14.7 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 EGO23255.1 - 0.02 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGO23255.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 EGO23255.1 - 0.036 13.8 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EGO23255.1 - 0.04 13.3 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TatD_DNase PF01026.21 EGO23256.1 - 3.4e-39 134.7 0.1 4.4e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase DUF4518 PF15008.6 EGO23257.1 - 0.14 11.4 0.1 0.41 9.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4518) BTB PF00651.31 EGO23259.1 - 0.012 15.8 0.0 0.056 13.7 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain Solute_trans_a PF03619.16 EGO23262.1 - 1.3e-83 280.6 18.4 1.5e-83 280.4 18.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glycos_transf_4 PF00953.21 EGO23262.1 - 0.43 10.5 8.4 0.12 12.4 3.5 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 4 GPI-anchored PF10342.9 EGO23263.1 - 0.00056 20.6 1.5 0.0012 19.6 1.5 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EGO23263.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 EGO23263.1 - 0.032 13.7 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UQ_con PF00179.26 EGO23264.1 - 3.7e-07 29.9 0.0 1.3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_A PF14457.6 EGO23264.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family A Acid_PPase PF12689.7 EGO23265.1 - 9.2e-59 198.1 0.0 1.1e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 EGO23265.1 - 0.16 12.2 0.1 2.1 8.6 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase OPT PF03169.15 EGO23267.1 - 2e-129 433.0 54.9 5.5e-127 425.0 54.9 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein rve PF00665.26 EGO23268.1 - 1.4e-05 25.3 0.0 3.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SnoaL_2 PF12680.7 EGO23268.1 - 2.7e-05 24.7 0.0 4.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGO23268.1 - 0.003 17.4 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DDE_3 PF13358.6 EGO23268.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Pox_G9-A16 PF03003.16 EGO23269.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 p450 PF00067.22 EGO23270.1 - 4.7e-28 98.2 0.0 6.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23271.1 - 1.3e-63 215.4 0.0 1.7e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23273.1 - 7.7e-23 81.0 0.0 8.5e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Retrotrans_gag PF03732.17 EGO23275.1 - 1.2e-08 35.1 0.2 1.2e-08 35.1 0.2 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO23275.1 - 4.6e-08 32.8 5.2 8.9e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO23275.1 - 0.54 10.3 9.0 0.046 13.7 3.3 2.1 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO23276.1 - 6.5e-08 32.7 0.1 6.5e-08 32.7 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO23277.1 - 6.8e-06 25.9 2.4 1.2e-05 25.2 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO23277.1 - 0.0088 16.0 0.4 0.016 15.2 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle NAD_binding_4 PF07993.12 EGO23278.1 - 5e-48 163.5 0.0 7.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGO23278.1 - 1.4e-09 38.2 0.0 3.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EGO23278.1 - 0.00018 20.6 0.1 0.00055 19.0 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO23278.1 - 0.00044 19.8 0.0 0.0014 18.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family BioY PF02632.14 EGO23278.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 BioY family AMP-binding_C PF13193.6 EGO23279.1 - 3.9e-07 30.9 0.0 8.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGO23280.1 - 0.00031 19.5 0.0 0.00053 18.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 EGO23281.1 - 2.4e-10 39.6 0.0 2.7e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.22 EGO23282.1 - 9.2e-37 126.9 0.0 1.3e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EGO23283.1 - 1.1e-68 231.8 0.0 1.6e-68 231.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGO23283.1 - 7.8e-16 57.8 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Methyltransf_25 PF13649.6 EGO23283.1 - 1.2e-12 48.3 0.0 4.6e-12 46.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23283.1 - 7e-12 45.4 0.0 1.7e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO23283.1 - 4.7e-11 43.3 0.0 1.9e-10 41.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO23283.1 - 6.4e-11 42.8 0.0 4.7e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO23283.1 - 4.4e-08 33.1 0.0 9.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO23283.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PP-binding PF00550.25 EGO23283.1 - 1.8e-06 28.2 0.0 7.7e-06 26.2 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGO23283.1 - 2.2e-06 28.5 0.1 5.3e-05 24.1 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_20 PF12147.8 EGO23283.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGO23283.1 - 0.0022 17.6 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGO23283.1 - 0.0041 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase tRNA_U5-meth_tr PF05958.11 EGO23283.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.18 EGO23283.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGO23283.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGO23283.1 - 0.023 14.3 0.1 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EGO23283.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 EGO23283.1 - 0.057 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 EGO23283.1 - 0.062 13.2 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 EGO23283.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GH3 PF03321.13 EGO23283.1 - 0.17 10.7 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter HTH_23 PF13384.6 EGO23284.1 - 0.043 13.6 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Aldo_ket_red PF00248.21 EGO23286.1 - 4.6e-71 239.4 0.0 5.2e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 EGO23287.1 - 1.3e-74 251.4 0.0 2e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGO23287.1 - 4.5e-14 52.0 0.0 6.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Methyltransf_25 PF13649.6 EGO23287.1 - 2.3e-12 47.4 0.2 1.2e-11 45.1 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO23287.1 - 4.3e-11 43.3 0.0 1.9e-10 41.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 EGO23287.1 - 9.2e-11 42.6 0.2 1.9e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.12 EGO23287.1 - 9.7e-11 42.3 0.0 4.7e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO23287.1 - 1.2e-08 35.0 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23287.1 - 6.7e-08 32.5 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGO23287.1 - 5.4e-07 29.9 0.0 3.9e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site CMAS PF02353.20 EGO23287.1 - 0.00077 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGO23287.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGO23287.1 - 0.0023 17.7 0.0 0.0077 16.0 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase CheR PF01739.18 EGO23287.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain NodS PF05401.11 EGO23287.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 EGO23287.1 - 0.027 14.1 0.0 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EGO23287.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.22 EGO23288.1 - 8.6e-36 123.7 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23289.1 - 1.2e-43 149.6 0.0 1.4e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec23_helical PF04815.15 EGO23289.1 - 0.039 13.8 0.2 9 6.2 0.0 2.6 2 1 0 2 2 2 0 Sec23/Sec24 helical domain FAD_binding_3 PF01494.19 EGO23290.1 - 8.4e-19 68.0 0.0 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGO23290.1 - 0.031 14.5 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Piwi PF02171.17 EGO23293.1 - 4.3e-77 259.3 0.0 7.1e-77 258.6 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EGO23293.1 - 6.5e-15 54.6 0.0 1.9e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EGO23293.1 - 3.4e-13 50.4 0.0 1.1e-12 48.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EGO23293.1 - 8.7e-13 48.4 0.1 2.8e-12 46.8 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EGO23293.1 - 1.3e-10 41.2 0.4 2.7e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGO23293.1 - 0.00038 20.6 0.3 0.00096 19.4 0.3 1.7 1 0 0 1 1 1 1 Mid domain of argonaute FMO-like PF00743.19 EGO23297.1 - 2e-11 43.1 0.0 1e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO23297.1 - 6.4e-10 38.7 0.7 0.0002 20.7 0.0 3.4 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO23297.1 - 1.9e-08 34.4 2.0 7.4e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGO23297.1 - 8.8e-08 31.7 0.0 5.8e-05 22.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGO23297.1 - 2.2e-07 30.8 0.9 6e-06 26.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO23297.1 - 3.7e-05 23.1 1.0 2.1 7.5 0.0 4.4 4 1 1 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO23297.1 - 7.1e-05 22.3 0.1 0.00058 19.3 0.1 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EGO23297.1 - 0.00011 21.6 2.4 0.17 11.2 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGO23297.1 - 0.00012 22.6 1.3 0.23 12.0 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO23297.1 - 0.0015 18.0 3.7 0.0068 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO23297.1 - 0.0022 18.0 1.8 0.024 14.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EGO23297.1 - 0.0053 16.6 0.1 0.0053 16.6 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EGO23297.1 - 0.015 14.4 5.4 0.078 12.0 0.2 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGO23297.1 - 0.016 14.3 6.1 0.087 11.9 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EGO23297.1 - 0.038 12.7 4.5 0.24 10.1 0.5 2.3 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 EGO23297.1 - 0.067 13.2 0.1 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGO23297.1 - 0.086 12.2 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EGO23297.1 - 0.19 10.7 0.1 0.41 9.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EGO23297.1 - 0.22 10.7 1.3 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_18 PF00704.28 EGO23298.1 - 2.6e-14 53.7 1.0 3.8e-14 53.1 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mito_carr PF00153.27 EGO23299.1 - 3.7e-19 68.4 9.4 1.6e-08 34.3 0.4 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CSL PF05207.13 EGO23300.1 - 4.4e-23 80.8 0.8 5.1e-23 80.6 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EGO23300.1 - 0.00096 19.2 0.8 0.0014 18.7 0.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EGO23300.1 - 0.061 13.3 0.4 0.093 12.7 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 EGO23300.1 - 0.074 12.9 2.0 0.13 12.0 2.0 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 EGO23300.1 - 0.091 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 GAGA factor Terminase_GpA PF05876.12 EGO23300.1 - 0.26 9.8 0.6 0.31 9.6 0.6 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) GIDA PF01134.22 EGO23301.1 - 8.5e-156 518.9 0.0 1e-155 518.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGO23301.1 - 9.7e-66 221.9 0.0 1.5e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EGO23301.1 - 1.3e-09 37.7 2.0 1.4e-05 24.5 0.4 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO23301.1 - 5.9e-09 35.8 0.4 1.3e-08 34.7 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO23301.1 - 0.00015 20.9 0.9 0.00031 19.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGO23301.1 - 0.00098 17.9 0.2 0.055 12.2 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EGO23301.1 - 0.0021 17.4 0.2 0.0048 16.2 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EGO23301.1 - 0.0059 16.2 0.6 0.42 10.1 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO23301.1 - 0.029 14.9 0.1 0.1 13.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO23301.1 - 0.032 13.5 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO23301.1 - 0.047 12.9 0.2 0.092 12.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 EGO23301.1 - 0.15 12.3 1.1 0.4 10.9 1.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2470 PF10615.9 EGO23302.1 - 1.6e-19 70.3 0.1 2.5e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EGO23302.1 - 1e-06 28.9 0.2 2.1e-06 28.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) DIM1 PF02966.16 EGO23303.1 - 1.8e-68 228.4 0.1 2e-68 228.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGO23303.1 - 1.2e-05 25.2 0.0 1.6e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGO23303.1 - 0.021 15.1 0.5 0.034 14.5 0.4 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.15 EGO23303.1 - 0.027 14.5 0.3 0.048 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 TFIIS_M PF07500.14 EGO23304.1 - 8.7e-31 106.7 0.1 8.7e-31 106.7 0.1 2.4 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGO23304.1 - 3.8e-18 65.1 9.7 6.2e-18 64.4 9.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGO23304.1 - 2.5e-09 37.0 4.2 4.2e-09 36.3 1.4 2.3 1 1 0 2 2 2 1 TFIIS helical bundle-like domain WD40 PF00400.32 EGO23305.1 - 1.1e-40 136.8 16.5 4.3e-08 33.7 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO23305.1 - 0.00086 19.6 0.8 0.95 9.8 0.1 4.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO23305.1 - 0.0022 16.7 0.5 2.2 6.8 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGO23305.1 - 0.24 10.7 0.0 0.57 9.5 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain NAD_binding_4 PF07993.12 EGO23306.1 - 1.9e-34 119.0 0.0 2.7e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO23306.1 - 5.4e-14 51.6 0.0 4.6e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EGO23306.1 - 2.6e-12 46.7 0.0 4.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO23306.1 - 2.4e-05 23.9 0.0 6e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO23306.1 - 0.00012 22.0 0.0 0.0025 17.7 0.0 2.6 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EGO23306.1 - 0.00059 19.8 0.1 0.0017 18.3 0.1 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGO23306.1 - 0.00059 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EGO23306.1 - 0.13 12.7 0.0 0.79 10.1 0.0 2.2 1 1 0 1 1 1 0 Phosphopantetheine attachment site AA_permease_2 PF13520.6 EGO23307.1 - 3.6e-77 260.0 45.0 4.4e-77 259.7 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO23307.1 - 3e-18 65.7 38.0 4.4e-18 65.1 38.0 1.2 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 EGO23308.1 - 1.3e-06 28.2 0.6 3.8e-06 26.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO23308.1 - 0.021 14.7 2.7 0.021 14.7 2.7 2.0 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 EGO23308.1 - 0.062 13.2 1.5 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 F-box C2 PF00168.30 EGO23309.1 - 0.00095 19.4 0.0 0.0011 19.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain DNApol3-delta_C PF09115.10 EGO23310.1 - 0.1 13.1 0.1 0.11 13.0 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal SNF2_N PF00176.23 EGO23312.1 - 2.2e-62 210.8 0.0 8.9e-62 208.8 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO23312.1 - 1.5e-18 67.2 0.0 8.3e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO23312.1 - 8.2e-10 38.9 0.0 9.2e-09 35.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO23312.1 - 1.8e-05 24.1 0.0 7.3e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ITAM PF02189.15 EGO23312.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif Terpene_synth_C PF03936.16 EGO23313.1 - 7e-06 25.6 0.3 2.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 EGO23313.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Plavaka PF18759.1 EGO23314.1 - 4.9e-60 203.5 0.0 5.4e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Phosphodiest PF01663.22 EGO23316.1 - 1.8e-08 34.4 0.4 3.6e-08 33.4 0.4 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGO23316.1 - 0.021 14.2 0.0 0.057 12.8 0.0 1.7 1 1 1 2 2 2 0 Sulfatase DUF1462 PF07315.11 EGO23317.1 - 0.059 13.7 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) ubiquitin PF00240.23 EGO23317.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 EGO23318.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGO23318.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO23318.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGO23318.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO23318.1 - 0.0054 16.7 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO23318.1 - 0.032 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family PIN_12 PF16289.5 EGO23320.1 - 0.026 15.0 1.7 0.028 14.9 0.4 1.8 2 1 0 2 2 2 0 PIN domain DUF2791 PF10923.8 EGO23320.1 - 0.045 12.6 0.5 0.076 11.8 0.5 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Plavaka PF18759.1 EGO23322.1 - 9.4e-36 123.7 0.0 4.6e-34 118.1 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase Ssl1 PF04056.14 EGO23323.1 - 0.084 12.7 0.1 0.24 11.2 0.1 1.7 2 0 0 2 2 2 0 Ssl1-like EzrA PF06160.12 EGO23324.1 - 0.24 9.5 0.0 0.26 9.4 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ABC_membrane PF00664.23 EGO23327.1 - 1.2e-56 192.4 38.7 4.8e-28 98.6 12.9 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO23327.1 - 1.3e-49 168.3 0.0 5.3e-27 95.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO23327.1 - 1.4e-06 28.0 2.2 0.0019 17.6 1.2 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO23327.1 - 7.2e-06 26.1 0.5 0.042 13.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGO23327.1 - 1.8e-05 25.4 0.9 0.27 11.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGO23327.1 - 0.00018 21.5 0.3 0.65 9.9 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGO23327.1 - 0.00024 21.5 0.0 0.83 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGO23327.1 - 0.00038 20.1 2.2 0.21 11.3 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGO23327.1 - 0.00057 19.8 1.0 1.4 8.6 0.1 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 EGO23327.1 - 0.0018 18.0 0.0 0.55 9.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EGO23327.1 - 0.005 17.1 4.3 7 6.9 0.2 4.1 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGO23327.1 - 0.0069 15.7 0.5 1.9 7.8 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EGO23327.1 - 0.021 14.5 2.3 4.7 6.9 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGO23327.1 - 0.029 13.9 0.1 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGO23327.1 - 0.03 14.5 0.5 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EGO23327.1 - 0.034 14.1 0.1 0.92 9.5 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2716 PF10898.8 EGO23327.1 - 0.037 14.4 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) AAA_7 PF12775.7 EGO23327.1 - 0.044 13.3 0.2 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EGO23327.1 - 0.048 13.7 1.3 4.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EGO23327.1 - 0.066 12.9 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGO23327.1 - 0.073 12.0 1.8 3 6.7 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 EGO23327.1 - 0.19 11.8 1.9 0.85 9.7 0.2 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EGO23327.1 - 0.22 11.2 0.8 22 4.7 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 EGO23327.1 - 0.31 10.6 1.3 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGO23327.1 - 0.74 9.7 2.1 1.6 8.6 0.3 2.2 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 EGO23327.1 - 1.2 8.8 3.3 55 3.4 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FAD_binding_3 PF01494.19 EGO23328.1 - 8.6e-22 77.8 0.0 7.4e-21 74.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO23328.1 - 0.0038 16.5 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO23328.1 - 0.0092 16.2 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ELF PF03317.13 EGO23328.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 ELF protein p450 PF00067.22 EGO23329.1 - 4.6e-63 213.6 0.0 5.7e-42 144.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Retrotrans_gag PF03732.17 EGO23330.1 - 8.5e-09 35.6 0.3 8.5e-09 35.6 0.3 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein KDZ PF18758.1 EGO23333.1 - 7e-52 176.3 4.9 7.9e-49 166.3 0.4 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Strep_his_triad PF04270.13 EGO23333.1 - 0.098 12.7 0.7 0.27 11.3 0.3 2.0 2 0 0 2 2 2 0 Streptococcal histidine triad protein zf-C2H2 PF00096.26 EGO23334.1 - 0.022 15.2 0.0 0.06 13.8 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF4085 PF13315.6 EGO23334.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Myb_DNA-bind_3 PF12776.7 EGO23335.1 - 1.4e-12 48.4 0.0 2.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HTH_23 PF13384.6 EGO23336.1 - 8.6e-07 28.6 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EGO23336.1 - 0.014 15.6 0.3 0.066 13.3 0.3 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EGO23336.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4 PF04545.16 EGO23336.1 - 0.028 13.9 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 EGO23336.1 - 0.058 13.6 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.22 EGO23337.1 - 1.4e-70 238.4 0.0 1.9e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23338.1 - 2e-15 56.5 0.0 2.1e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.22 EGO23339.1 - 1.4e-20 73.8 13.0 2.4e-13 50.0 3.6 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Cellulase PF00150.18 EGO23340.1 - 6.4e-50 170.2 0.0 8.1e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EGO23340.1 - 1.5e-12 47.2 7.5 1.5e-12 47.2 7.5 3.0 4 0 0 4 4 4 1 Fungal cellulose binding domain Aldedh PF00171.22 EGO23341.1 - 2.8e-177 589.9 0.1 3.4e-177 589.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO23341.1 - 0.046 12.8 0.0 0.18 10.8 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) WSC PF01822.19 EGO23342.1 - 3.1e-69 229.2 59.6 9.1e-18 64.2 9.9 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 EGO23342.1 - 3.5e-28 98.4 0.0 4.6e-27 94.8 0.0 2.6 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGO23342.1 - 9.4e-19 67.5 0.0 2.5e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 EGO23342.1 - 0.063 13.3 0.9 1.6 8.8 0.0 3.7 4 0 0 4 4 4 0 Kelch motif DUF5122 PF17164.4 EGO23342.1 - 0.49 10.7 2.9 51 4.3 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller PAN_3 PF08277.12 EGO23342.1 - 2.8 7.8 14.8 6.1 6.7 1.7 4.4 4 0 0 4 4 4 0 PAN-like domain Hydrophobin PF01185.18 EGO23343.1 - 1.4e-22 80.1 5.4 1.7e-22 79.8 5.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CBF PF03914.17 EGO23344.1 - 5.5e-40 137.2 2.1 9e-39 133.2 0.1 2.9 3 0 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 EGO23344.1 - 0.0078 16.3 1.3 0.013 15.5 0.1 2.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGO23344.1 - 0.09 11.3 0.3 0.17 10.4 0.1 1.5 2 0 0 2 2 2 0 Adaptin N terminal region DUF3123 PF11321.8 EGO23344.1 - 6.2 7.5 5.9 1.3 9.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) AhpC-TSA PF00578.21 EGO23345.1 - 2.4e-38 130.9 0.0 3.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO23345.1 - 3e-15 56.2 0.0 3.9e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGO23345.1 - 2.6e-10 40.0 0.0 4.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGO23345.1 - 0.058 13.3 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC AAA PF00004.29 EGO23346.1 - 1.1e-73 245.9 0.0 2.9e-40 137.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO23346.1 - 7.2e-25 86.5 0.1 1.1e-12 47.6 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGO23346.1 - 2.2e-12 47.7 1.0 6e-05 23.5 0.1 4.4 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EGO23346.1 - 4.4e-12 46.0 0.0 0.00043 20.1 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO23346.1 - 4.3e-11 43.0 0.0 1.7e-05 24.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO23346.1 - 2.2e-08 34.5 0.1 0.0004 20.7 0.0 4.2 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 EGO23346.1 - 2.2e-08 34.4 0.0 0.00081 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGO23346.1 - 8.9e-08 32.4 0.0 0.00047 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGO23346.1 - 1.2e-07 31.3 0.0 0.0031 16.8 0.0 2.5 3 0 0 3 3 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 EGO23346.1 - 3e-07 30.3 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EGO23346.1 - 1.6e-05 25.0 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGO23346.1 - 0.00015 22.1 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 EGO23346.1 - 0.00017 21.5 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGO23346.1 - 0.00027 20.4 0.3 0.25 10.7 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGO23346.1 - 0.00031 20.4 0.2 4.2 6.9 0.0 3.8 3 1 1 4 4 4 1 AAA domain Zeta_toxin PF06414.12 EGO23346.1 - 0.00032 20.0 0.0 0.023 14.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EGO23346.1 - 0.00039 21.0 0.0 0.0056 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGO23346.1 - 0.00063 19.6 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGO23346.1 - 0.0011 19.0 0.4 0.73 9.7 0.0 3.4 2 2 1 3 3 3 1 Rad17 P-loop domain AAA_28 PF13521.6 EGO23346.1 - 0.0011 19.3 0.0 0.086 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO23346.1 - 0.0014 18.2 0.0 0.5 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EGO23346.1 - 0.0017 18.3 0.0 0.1 12.5 0.0 3.2 4 0 0 4 4 3 1 NACHT domain Viral_helicase1 PF01443.18 EGO23346.1 - 0.0061 16.3 0.0 0.26 11.0 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EGO23346.1 - 0.0065 16.3 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGO23346.1 - 0.0097 15.6 0.1 0.7 9.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EGO23346.1 - 0.012 15.3 0.0 1 9.0 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGO23346.1 - 0.013 16.1 0.0 0.33 11.5 0.0 2.8 3 1 0 3 3 2 0 ABC transporter AAA_24 PF13479.6 EGO23346.1 - 0.014 15.1 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGO23346.1 - 0.023 14.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DAP3 PF10236.9 EGO23346.1 - 0.023 13.8 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 EGO23346.1 - 0.032 13.6 0.0 4.5 6.6 0.0 2.4 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 EGO23346.1 - 0.054 12.7 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.6 EGO23346.1 - 0.073 13.2 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EGO23346.1 - 0.078 12.1 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EGO23346.1 - 0.12 12.2 0.0 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein ATPase_2 PF01637.18 EGO23346.1 - 0.16 11.9 0.0 15 5.4 0.0 2.9 2 2 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGO23346.1 - 0.16 12.3 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_18 PF13512.6 EGO23346.1 - 0.22 11.6 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat F1F0-ATPsyn_F PF10791.9 EGO23350.1 - 2.1e-32 111.4 0.0 2.4e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi CPBP PF02517.16 EGO23351.1 - 3.2e-17 62.7 2.5 3.2e-17 62.7 2.5 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2207 PF09972.9 EGO23351.1 - 0.52 9.0 2.5 0.21 10.3 0.2 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.16 EGO23354.1 - 2.2e-18 66.3 26.4 2.5e-18 66.1 26.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily EB1 PF03271.17 EGO23355.1 - 6.6e-17 61.5 3.1 1.4e-16 60.4 3.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EGO23355.1 - 2e-06 28.0 0.5 3.9e-06 27.0 0.3 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain Ras PF00071.22 EGO23359.1 - 9.9e-55 184.5 0.0 1.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO23359.1 - 8.6e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO23359.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO23359.1 - 0.0032 16.9 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGO23359.1 - 0.23 10.8 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AKAP7_NLS PF10469.9 EGO23360.1 - 5.3e-26 91.8 0.0 1e-25 90.9 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGO23360.1 - 0.006 16.5 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Asp PF00026.23 EGO23361.1 - 4.9e-35 121.5 0.1 3.6e-34 118.6 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO23361.1 - 2.1e-07 31.3 0.9 3.8e-06 27.3 0.9 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Sugar_tr PF00083.24 EGO23362.1 - 3.2e-52 177.9 16.3 4.4e-52 177.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO23362.1 - 1.3e-22 80.3 23.0 2.8e-16 59.4 1.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGO23362.1 - 9.1e-05 20.9 0.1 9.1e-05 20.9 0.1 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_15 PF00723.21 EGO23364.1 - 6.6e-53 180.1 0.0 1.1e-52 179.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Abhydrolase_1 PF00561.20 EGO23365.1 - 3.5e-14 53.1 0.4 2.9e-13 50.1 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO23365.1 - 1.5e-12 48.6 0.0 1.9e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO23365.1 - 1.3e-08 34.4 0.0 4.4e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Pneumo_M2 PF07380.11 EGO23365.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus M2 protein Glyco_transf_11 PF01531.16 EGO23366.1 - 0.014 14.6 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 Pkinase_fungal PF17667.1 EGO23369.1 - 1.6e-24 86.4 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO23369.1 - 1.4e-08 34.5 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGO23369.1 - 0.053 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ribosomal_L24 PF17136.4 EGO23369.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 zf-CCHC_3 PF13917.6 EGO23371.1 - 1.1e-05 25.2 3.3 1.9e-05 24.5 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO23371.1 - 1.4e-05 25.0 5.1 1.4e-05 25.0 5.1 1.7 2 0 0 2 2 2 1 Zinc knuckle Pkinase_fungal PF17667.1 EGO23372.1 - 2.4e-25 89.2 0.0 2.9e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO23372.1 - 3.7e-07 29.8 0.0 3.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23372.1 - 0.014 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase GyrI-like PF06445.15 EGO23372.1 - 0.13 12.5 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 GyrI-like small molecule binding domain NACHT PF05729.12 EGO23374.1 - 2.4e-05 24.3 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGO23374.1 - 4e-05 23.9 0.0 6.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGO23374.1 - 0.00038 19.8 0.2 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGO23374.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGO23374.1 - 0.016 15.6 0.0 0.039 14.3 0.0 1.7 2 1 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EGO23374.1 - 0.021 15.4 0.1 0.2 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EGO23374.1 - 0.033 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 EGO23374.1 - 0.057 12.7 0.0 0.84 8.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.25 EGO23374.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 EGO23374.1 - 0.23 10.4 0.0 0.57 9.1 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ank_2 PF12796.7 EGO23375.1 - 5.1e-05 23.8 0.0 0.00023 21.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO23375.1 - 5.5e-05 23.4 0.0 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGO23375.1 - 0.0014 19.2 0.2 0.047 14.3 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) MCRA PF06100.11 EGO23376.1 - 0.075 11.8 0.1 0.091 11.5 0.1 1.1 1 0 0 1 1 1 0 MCRA family Peptidase_S10 PF00450.22 EGO23378.1 - 1.1e-93 315.0 6.7 1.4e-93 314.6 6.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3602 PF12223.8 EGO23379.1 - 0.079 13.6 3.3 0.13 12.9 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) PKD PF00801.20 EGO23380.1 - 0.0083 15.9 0.2 4.3 7.3 0.1 2.7 2 0 0 2 2 2 2 PKD domain SE PF08491.10 EGO23381.1 - 2.2e-94 315.6 0.0 2.9e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGO23381.1 - 1.4e-10 40.9 0.2 7.1e-10 38.7 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO23381.1 - 3.6e-10 40.0 0.0 0.00057 19.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO23381.1 - 6.1e-05 22.3 1.7 0.036 13.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGO23381.1 - 0.00034 20.0 0.1 0.00074 18.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO23381.1 - 0.0044 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO23381.1 - 0.011 15.0 0.0 0.054 12.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 EGO23381.1 - 0.013 14.3 0.7 1.5 7.6 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EGO23381.1 - 0.044 12.8 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EGO23381.1 - 0.094 12.7 0.1 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EGO23381.1 - 0.14 11.2 0.4 2.8 6.9 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF5371 PF17341.2 EGO23381.1 - 0.23 11.7 0.0 0.52 10.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5371) DUF2304 PF10066.9 EGO23382.1 - 0.92 9.8 14.3 0.041 14.1 3.5 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Complex1_51K PF01512.17 EGO23384.1 - 8.3e-48 162.1 0.0 1.2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGO23384.1 - 3.8e-30 103.8 1.3 5e-30 103.4 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGO23384.1 - 3.9e-08 33.0 0.0 1.1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DSPc PF00782.20 EGO23386.1 - 1.3e-28 99.4 0.0 1.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGO23386.1 - 0.00085 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGO23386.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SIR2 PF02146.17 EGO23387.1 - 0.0013 18.7 0.1 0.0026 17.7 0.0 1.5 2 0 0 2 2 2 1 Sir2 family adh_short PF00106.25 EGO23389.1 - 7e-21 74.6 0.0 1.2e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23389.1 - 2.7e-10 40.2 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO23389.1 - 7e-05 22.8 0.0 0.00019 21.4 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF3806 PF12713.7 EGO23389.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) TPP_enzyme_N PF02776.18 EGO23390.1 - 1.2e-38 132.4 0.1 3.3e-38 131.0 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGO23390.1 - 4.2e-12 46.1 0.0 8.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO23390.1 - 1.2e-06 28.3 0.0 4.1e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Arrestin_N PF00339.29 EGO23391.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain F-box-like PF12937.7 EGO23392.1 - 1.6e-07 31.1 0.1 4.5e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EGO23392.1 - 0.00095 19.1 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like domain Glyco_hydro_18 PF00704.28 EGO23393.1 - 4.8e-26 92.2 1.2 9.9e-26 91.2 1.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12_2 PF14600.6 EGO23393.1 - 3.9e-06 26.7 19.8 2.9e-05 23.9 4.2 2.6 2 0 0 2 2 2 2 Cellulose-binding domain CBM_5_12 PF02839.14 EGO23393.1 - 0.0031 18.0 1.4 0.0031 18.0 1.4 3.9 3 0 0 3 3 3 2 Carbohydrate binding domain VOMI PF03762.17 EGO23393.1 - 0.099 12.8 4.8 0.67 10.1 2.6 2.8 2 1 0 2 2 2 0 Vitelline membrane outer layer protein I (VOMI) Peptidase_S10 PF00450.22 EGO23394.1 - 3.1e-95 320.0 4.0 4e-95 319.7 4.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase FA_desaturase PF00487.24 EGO23396.1 - 6.5e-26 91.7 30.7 9.7e-26 91.1 30.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGO23396.1 - 4.8e-08 33.0 0.0 9.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 2OG-FeII_Oxy_3 PF13640.6 EGO23397.1 - 1.2e-09 38.9 0.0 4.7e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ArfGap PF01412.18 EGO23398.1 - 1.2e-33 115.7 0.2 1.2e-33 115.7 0.2 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Clat_adaptor_s PF01217.20 EGO23399.1 - 2.8e-56 189.4 2.8 3.1e-56 189.3 2.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain F-box-like PF12937.7 EGO23400.1 - 0.0065 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like CsbD PF05532.12 EGO23402.1 - 2.4e-12 46.6 16.7 2.7e-08 33.6 4.9 2.1 1 1 1 2 2 2 2 CsbD-like Coprogen_oxidas PF01218.18 EGO23403.1 - 1.1e-61 208.2 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Sec_GG PF07549.14 EGO23404.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif DUF5025 PF16428.5 EGO23406.1 - 0.14 12.3 0.1 0.34 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5025) Sec_GG PF07549.14 EGO23407.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif UQ_con PF00179.26 EGO23408.1 - 2.7e-43 147.0 0.0 3.3e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EGO23408.1 - 2.7e-19 68.7 0.5 4.8e-19 67.9 0.5 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EGO23408.1 - 0.0029 17.3 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.14 EGO23408.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 FeoA domain Acetyltransf_1 PF00583.25 EGO23410.1 - 2.8e-07 30.8 0.0 3.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO23410.1 - 8.2e-07 29.0 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO23410.1 - 0.0007 20.0 0.0 0.00096 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EGO23412.1 - 2.3e-28 99.2 42.3 2.6e-26 92.4 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_C_16 PF17920.1 EGO23412.1 - 2 8.7 7.2 1.9 8.8 0.6 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Ammonium_transp PF00909.21 EGO23414.1 - 0.004 15.9 4.5 0.0049 15.6 4.5 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3382 PF11862.8 EGO23414.1 - 0.25 11.6 6.6 0.081 13.2 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) MFS_1 PF07690.16 EGO23415.1 - 5.9e-22 78.1 25.6 7.7e-22 77.7 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGO23415.1 - 3.3e-06 26.7 5.7 4.4e-06 26.2 5.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ESSS PF10183.9 EGO23415.1 - 0.078 13.2 0.1 7.6 6.8 0.1 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 EGO23416.1 - 1.8e-21 76.5 35.4 1.8e-21 76.5 35.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_3 PF00591.21 EGO23417.1 - 2.4e-59 201.0 0.3 3.5e-45 154.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGO23417.1 - 2e-09 37.1 0.0 6.5e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain HisG PF01634.18 EGO23418.1 - 1.1e-52 178.2 0.1 1.5e-52 177.8 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGO23418.1 - 8.7e-28 96.3 0.1 2.3e-27 94.9 0.1 1.8 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EGO23418.1 - 0.00062 19.8 0.1 0.001 19.1 0.1 1.3 1 1 0 1 1 1 1 NMT1/THI5 like F-box-like PF12937.7 EGO23419.1 - 4.1e-09 36.2 0.5 1.5e-08 34.4 0.5 2.1 1 0 0 1 1 1 1 F-box-like Rot1 PF10681.9 EGO23421.1 - 3.2e-57 193.4 1.6 3.7e-57 193.2 1.6 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Proteasome PF00227.26 EGO23422.1 - 2.2e-32 112.1 0.0 2.6e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Retrotrans_gag PF03732.17 EGO23425.1 - 4.2e-07 30.2 0.6 5.3e-07 29.8 0.6 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein COG5 PF10392.9 EGO23426.1 - 0.063 13.5 0.6 0.099 12.8 0.6 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 AMP-binding PF00501.28 EGO23427.1 - 8e-30 103.8 0.0 5e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGO23427.1 - 4.8e-28 98.0 0.0 7.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGO23427.1 - 1.1e-09 38.1 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO23427.1 - 0.00098 19.4 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Tafi-CsgC PF10610.9 EGO23428.1 - 0.16 12.2 0.2 0.83 9.9 0.0 2.1 2 0 0 2 2 2 0 Thin aggregative fimbriae synthesis protein DUF4133 PF13571.6 EGO23428.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) DUF2628 PF10947.8 EGO23428.1 - 0.3 11.5 3.5 2 8.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF5453 PF17534.2 EGO23429.1 - 0.33 10.9 5.6 0.17 11.8 3.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5453) Med7 PF05983.11 EGO23430.1 - 2.2e-36 125.8 1.1 2.7e-35 122.2 1.1 2.0 1 1 0 1 1 1 1 MED7 protein DEAD PF00270.29 EGO23433.1 - 5.6e-07 29.5 0.0 1.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO23433.1 - 9.9e-06 25.9 0.0 3.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain T4SS-DNA_transf PF02534.14 EGO23433.1 - 0.0014 17.5 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer IHO1 PF15771.5 EGO23433.1 - 0.014 14.2 0.3 0.022 13.6 0.3 1.2 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Retrotrans_gag PF03732.17 EGO23434.1 - 3.7e-09 36.7 0.2 3.7e-09 36.7 0.2 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO23434.1 - 2.8e-08 33.5 5.3 5.6e-08 32.5 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO23434.1 - 0.029 14.3 1.7 0.069 13.1 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle SUIM_assoc PF16619.5 EGO23434.1 - 0.42 10.7 0.1 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FlxA PF14282.6 EGO23434.1 - 0.73 9.9 4.4 0.96 9.5 0.1 2.5 2 0 0 2 2 2 0 FlxA-like protein HTH_23 PF13384.6 EGO23435.1 - 3.2e-05 23.6 0.0 5.8e-05 22.8 0.0 1.4 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EGO23435.1 - 0.023 14.3 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 F-box-like PF12937.7 EGO23438.1 - 1.1e-08 34.8 0.0 1.9e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 F-box-like LRR_1 PF00560.33 EGO23439.1 - 0.099 13.3 0.7 33 5.6 0.2 4.4 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 EGO23439.1 - 0.63 10.5 3.6 7.3 7.2 1.4 3.4 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Tam41_Mmp37 PF09139.11 EGO23441.1 - 3.3e-99 332.4 0.0 3.7e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Rtt106_N PF18215.1 EGO23441.1 - 0.029 14.1 0.1 9.7 6.0 0.2 2.8 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain COesterase PF00135.28 EGO23442.1 - 9.8e-88 295.2 0.0 2.8e-86 290.4 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO23442.1 - 0.012 15.5 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold APG12 PF04110.13 EGO23442.1 - 0.014 15.8 0.2 0.031 14.7 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Peptidase_S9 PF00326.21 EGO23442.1 - 0.027 13.9 0.2 0.047 13.2 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DER1 PF04511.15 EGO23443.1 - 5.2e-49 166.8 5.8 6.3e-49 166.5 5.8 1.0 1 0 0 1 1 1 1 Der1-like family HIT PF01230.23 EGO23444.1 - 8.3e-24 84.2 0.1 1.1e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO23444.1 - 9.5e-10 39.0 0.1 1.3e-09 38.5 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGO23444.1 - 0.0008 19.3 0.9 0.0016 18.3 0.9 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 S8_pro-domain PF16470.5 EGO23444.1 - 0.027 15.2 0.0 0.1 13.4 0.0 1.8 1 1 0 1 1 1 0 Peptidase S8 pro-domain COesterase PF00135.28 EGO23445.1 - 2.7e-88 297.1 0.0 2.1e-87 294.2 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO23445.1 - 0.01 15.7 0.0 0.073 12.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold F-box-like PF12937.7 EGO23447.1 - 7.4e-06 25.8 0.1 3.8e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 F-box-like Lipase_3 PF01764.25 EGO23449.1 - 1.6e-06 28.0 0.0 4.6e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO23449.1 - 0.018 15.7 0.1 0.034 14.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 EGO23449.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FAD_binding_4 PF01565.23 EGO23450.1 - 3.6e-22 78.6 0.3 5.6e-22 78.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO23450.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Sigma70_ner PF04546.13 EGO23450.1 - 4.4 7.1 5.6 0.91 9.4 2.1 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region PARP PF00644.20 EGO23451.1 - 3.2e-08 33.4 1.0 3.3e-07 30.1 1.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Aldo_ket_red PF00248.21 EGO23452.1 - 8.4e-46 156.5 0.0 1.1e-44 152.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Homeodomain PF00046.29 EGO23452.1 - 0.067 13.0 0.0 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain STOP PF05217.12 EGO23452.1 - 0.1 12.9 1.6 0.22 11.8 1.6 1.5 1 0 0 1 1 1 0 STOP protein SWI-SNF_Ssr4 PF08549.10 EGO23453.1 - 4.8e-23 81.7 1.7 4.3e-18 65.3 0.2 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1750) CG-1 PF03859.16 EGO23453.1 - 8.9e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 CG-1 domain Pkinase PF00069.25 EGO23454.1 - 7.5e-30 104.2 0.0 5.5e-29 101.3 0.0 2.1 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23454.1 - 1.4e-23 83.5 0.0 2.1e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO23454.1 - 0.00084 18.2 0.5 0.0019 17.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGO23454.1 - 0.047 12.6 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain F-box-like PF12937.7 EGO23455.1 - 7.4e-06 25.8 0.4 1.8e-05 24.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO23455.1 - 0.00035 20.4 0.6 0.0008 19.2 0.6 1.6 1 0 0 1 1 1 1 F-box domain Mannosidase_ig PF17786.1 EGO23456.1 - 0.0084 16.7 0.0 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Dev_Cell_Death PF10539.9 EGO23456.1 - 0.061 13.2 0.1 3.7 7.4 0.1 2.4 1 1 0 1 1 1 0 Development and cell death domain Chitin_synth_1 PF01644.17 EGO23457.1 - 2.7e-79 264.8 0.1 4.1e-79 264.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO23457.1 - 5e-27 93.7 0.0 1.1e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO23457.1 - 1.6e-23 83.1 1.6 5e-18 65.0 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO23457.1 - 0.11 12.4 16.6 8.2 6.3 16.6 2.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 adh_short PF00106.25 EGO23458.1 - 2.4e-33 115.3 0.0 3.1e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23458.1 - 1.4e-26 93.6 0.0 1.8e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EGO23458.1 - 9.8e-07 28.8 0.0 1.7e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO23458.1 - 7.1e-06 26.0 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGO23458.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EGO23458.1 - 0.027 14.1 0.1 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family F-box-like PF12937.7 EGO23461.1 - 2.9e-05 23.9 1.7 0.00012 21.9 1.7 2.1 1 1 0 1 1 1 1 F-box-like Trp_halogenase PF04820.14 EGO23462.1 - 7.9e-06 25.0 0.1 0.27 10.0 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase FAD_oxidored PF12831.7 EGO23462.1 - 4.6e-05 22.9 0.0 0.00013 21.5 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO23462.1 - 0.0032 16.8 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO23462.1 - 0.016 14.8 0.3 0.17 11.4 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase FapA PF03961.13 EGO23463.1 - 0.31 9.6 4.4 0.36 9.4 4.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Alg6_Alg8 PF03155.15 EGO23465.1 - 8.5e-137 457.0 25.6 1.1e-136 456.7 25.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 EGO23465.1 - 4.4 6.6 13.7 0.13 11.7 6.2 2.1 2 1 0 2 2 2 0 ALG3 protein 4HBT PF03061.22 EGO23467.1 - 1.2e-11 44.8 0.3 1.7e-11 44.3 0.3 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EGO23467.1 - 0.024 14.8 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF3452 PF11934.8 EGO23468.1 - 0.11 12.0 0.5 0.12 11.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) NACHT PF05729.12 EGO23469.1 - 7.4e-05 22.7 0.1 0.0001 22.2 0.1 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGO23469.1 - 0.0068 16.7 0.1 0.01 16.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain Ku_N PF03731.15 EGO23469.1 - 0.019 14.7 0.6 0.029 14.1 0.6 1.3 1 1 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Tma16 PF11176.8 EGO23469.1 - 0.023 14.6 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Rhodanese PF00581.20 EGO23469.1 - 0.12 12.9 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 Rhodanese-like domain Ca_bind_SSO6904 PF18249.1 EGO23469.1 - 0.13 12.6 1.0 0.63 10.4 0.2 2.1 1 1 1 2 2 2 0 Calcium binding protein SSO6904 TRI5 PF06330.11 EGO23470.1 - 0.00014 20.8 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) Bot1p PF12298.8 EGO23470.1 - 0.057 13.6 0.0 9.7 6.3 0.0 2.6 1 1 1 2 2 2 0 Eukaryotic mitochondrial regulator protein Cwf_Cwc_15 PF04889.12 EGO23473.1 - 0.014 15.1 7.1 0.015 15.0 7.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EBV-NA3 PF05009.12 EGO23473.1 - 0.14 11.7 0.9 0.14 11.6 0.9 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FAM176 PF14851.6 EGO23473.1 - 0.24 11.0 1.9 0.26 11.0 1.9 1.1 1 0 0 1 1 1 0 FAM176 family SRRM_C PF15230.6 EGO23473.1 - 0.4 11.3 3.4 0.5 11.0 3.4 1.2 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus DNA_pol_phi PF04931.13 EGO23473.1 - 0.62 8.1 5.0 0.58 8.2 5.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EGO23473.1 - 0.84 7.8 5.8 0.83 7.9 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein FMN_dh PF01070.18 EGO23474.1 - 1.8e-113 379.1 0.2 2.3e-113 378.8 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGO23474.1 - 1.4e-05 24.3 1.3 0.00015 20.9 0.1 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EGO23474.1 - 7.8e-05 22.1 0.5 0.12 11.7 0.0 3.2 3 1 0 4 4 4 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EGO23474.1 - 0.00054 19.2 0.1 0.00089 18.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EGO23474.1 - 0.0027 17.2 0.3 0.0041 16.6 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase WD40 PF00400.32 EGO23475.1 - 0.18 12.7 0.4 14 6.7 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Glyco_hydro_20 PF00728.22 EGO23476.1 - 2.8e-86 290.1 0.0 3.3e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGO23476.1 - 2.1e-10 41.4 0.0 3.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGO23476.1 - 0.0011 19.7 0.0 0.0024 18.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pre-SET PF05033.16 EGO23477.1 - 2.5e-20 73.1 3.2 2.5e-20 73.1 3.2 2.1 2 1 0 2 2 2 1 Pre-SET motif SET PF00856.28 EGO23477.1 - 3e-18 66.8 0.3 9.4e-18 65.2 0.2 1.9 2 1 0 2 2 2 1 SET domain FA_desaturase PF00487.24 EGO23478.1 - 4.4e-24 85.7 26.0 7.3e-24 85.0 26.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase SbcCD_C PF13558.6 EGO23479.1 - 4.1e-07 30.1 0.0 2e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGO23479.1 - 2e-06 27.8 4.4 1.5e-05 25.0 4.4 2.1 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system UPF0242 PF06785.11 EGO23479.1 - 0.0016 18.6 17.6 0.0016 18.6 17.6 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 EGO23479.1 - 0.0019 18.5 29.7 0.17 12.1 1.3 3.4 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EGO23479.1 - 0.0032 18.0 32.9 0.91 9.9 23.3 3.1 1 1 1 2 2 2 1 Fez1 SMC_N PF02463.19 EGO23479.1 - 0.0035 16.8 19.9 0.0062 16.0 19.9 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain GAS PF13851.6 EGO23479.1 - 0.0063 15.9 35.5 0.0085 15.5 13.9 3.3 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 EGO23479.1 - 0.0068 16.6 31.5 0.18 12.0 3.7 3.8 1 1 3 4 4 4 1 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EGO23479.1 - 0.0084 16.6 14.4 0.0084 16.6 14.4 3.6 1 1 2 3 3 3 1 Apg6 coiled-coil region ZapB PF06005.12 EGO23479.1 - 0.01 16.3 5.0 0.01 16.3 5.0 4.7 2 2 1 3 3 2 0 Cell division protein ZapB DUF812 PF05667.11 EGO23479.1 - 0.012 14.6 33.7 0.51 9.2 7.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) SlyX PF04102.12 EGO23479.1 - 0.062 13.9 21.9 1 10.0 0.2 4.7 3 2 1 4 4 4 0 SlyX NPV_P10 PF05531.12 EGO23479.1 - 0.083 13.4 16.9 1.9 9.0 0.1 4.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 EGO23479.1 - 0.11 12.2 9.3 2 8.1 2.8 3.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 EGO23479.1 - 0.12 12.6 27.3 0.39 10.9 2.2 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EGO23479.1 - 0.21 11.9 25.8 0.36 11.2 1.0 4.5 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 EGO23479.1 - 0.69 10.5 22.6 3.5 8.3 0.6 3.9 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 EGO23479.1 - 0.7 9.9 34.2 8.3 6.4 4.8 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 EGO23479.1 - 0.86 9.9 11.1 0.2 11.9 1.6 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 EGO23479.1 - 0.93 8.9 36.3 9.7 5.5 13.4 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 EGO23479.1 - 1.5 8.9 21.4 1.5 8.9 2.3 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EGO23479.1 - 1.6 8.8 22.7 6.4 6.9 0.1 5.1 2 2 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Lebercilin PF15619.6 EGO23479.1 - 2.1 8.0 35.0 1.9 8.1 17.1 3.8 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.20 EGO23479.1 - 2.3 8.2 29.4 5.6 7.0 2.2 4.5 2 2 1 3 3 3 0 Prefoldin subunit DUF3584 PF12128.8 EGO23479.1 - 2.3 5.6 32.8 0.71 7.3 20.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Tox-REase-7 PF15649.6 EGO23479.1 - 2.5 8.5 6.9 0.32 11.3 0.4 2.7 3 0 0 3 3 2 0 Restriction endonuclease fold toxin 7 DivIC PF04977.15 EGO23479.1 - 2.8 7.8 33.6 0.21 11.4 2.1 5.3 2 1 3 5 5 5 0 Septum formation initiator Occludin_ELL PF07303.13 EGO23479.1 - 2.8 8.7 20.9 5.4 7.8 0.4 4.2 1 1 3 4 4 4 0 Occludin homology domain SpecificRecomb PF10136.9 EGO23479.1 - 2.9 6.1 5.7 2 6.6 3.9 1.7 1 1 0 1 1 1 0 Site-specific recombinase DASH_Dam1 PF08653.10 EGO23479.1 - 2.9 7.7 9.1 16 5.4 0.1 4.8 5 0 0 5 5 5 0 DASH complex subunit Dam1 Prominin PF05478.11 EGO23479.1 - 3.4 5.5 24.4 3 5.7 4.2 2.6 1 1 2 3 3 3 0 Prominin DUF1192 PF06698.11 EGO23479.1 - 3.6 7.7 22.6 4.4 7.4 0.8 5.7 5 1 1 6 6 6 0 Protein of unknown function (DUF1192) HMMR_N PF15905.5 EGO23479.1 - 5.2 6.4 37.3 5.2 6.4 20.6 2.9 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fmp27_WPPW PF10359.9 EGO23479.1 - 5.9 5.6 27.3 0.42 9.4 9.3 3.1 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.7 EGO23479.1 - 6.1 7.0 36.8 10 6.2 22.7 3.7 1 1 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 EGO23479.1 - 7.2 5.4 36.1 0.89 8.4 14.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein HemX PF04375.14 EGO23479.1 - 9.8 5.4 22.3 2.9 7.1 1.4 3.3 2 1 1 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase ECH_1 PF00378.20 EGO23480.1 - 6.8e-78 261.4 0.0 7.6e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO23480.1 - 4.4e-37 128.3 0.2 3.6e-34 118.8 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SET PF00856.28 EGO23481.1 - 4e-11 43.6 0.0 7.1e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGO23481.1 - 7.9e-09 35.5 12.8 1.8e-08 34.3 12.8 1.6 1 0 0 1 1 1 1 MYND finger DUF4436 PF14494.6 EGO23482.1 - 4.3e-07 29.5 0.2 6.3e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Sigma_reg_N PF13800.6 EGO23482.1 - 0.056 13.7 0.1 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4969 PF16339.5 EGO23482.1 - 0.41 11.0 1.8 0.69 10.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) DIOX_N PF14226.6 EGO23483.1 - 6.9e-32 110.7 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO23483.1 - 1.2e-19 70.6 0.0 2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 EGO23484.1 - 1.5e-11 44.8 0.0 4.6e-11 43.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 EGO23484.1 - 2.5e-10 40.2 0.1 4.3e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGO23484.1 - 7.1e-10 39.4 0.0 5.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23484.1 - 1.7e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO23484.1 - 1.8e-07 31.1 0.0 5.6e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGO23484.1 - 3.2e-05 23.5 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGO23484.1 - 9.6e-05 23.1 1.4 0.00024 21.8 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGO23484.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGO23484.1 - 0.0043 16.8 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.14 EGO23484.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 EGO23484.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EGO23484.1 - 0.036 15.1 0.0 0.089 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EGO23484.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 EGO23484.1 - 0.047 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NFACT-R_1 PF05670.13 EGO23485.1 - 1.4e-38 131.8 0.0 2.7e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain RsgI_N PF12791.7 EGO23485.1 - 0.057 13.3 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 Anti-sigma factor N-terminus RRM_1 PF00076.22 EGO23486.1 - 2e-08 33.9 0.0 7.2e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EGO23486.1 - 3.2e-06 27.4 0.7 7.2e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 PWI domain DUF494 PF04361.13 EGO23486.1 - 0.061 13.2 2.7 0.14 12.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF494) Trehalase PF01204.18 EGO23487.1 - 4.9e-105 352.3 0.2 4.2e-95 319.5 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 EGO23487.1 - 0.0082 15.1 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Transposase_21 PF02992.14 EGO23488.1 - 1.7e-06 27.4 0.0 3.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 EGO23488.1 - 0.00043 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Plavaka PF18759.1 EGO23488.1 - 0.046 12.9 0.1 0.093 11.9 0.1 1.4 1 0 0 1 1 1 0 Plavaka transposase WD40 PF00400.32 EGO23491.1 - 4.8e-12 46.2 15.8 2.1e-07 31.5 0.1 5.8 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO23491.1 - 2.5e-09 37.3 0.2 0.11 12.8 0.0 4.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO23491.1 - 0.042 12.8 0.0 0.21 10.5 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LapA_dom PF06305.11 EGO23491.1 - 0.14 12.0 1.0 0.26 11.1 1.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CNH PF00780.22 EGO23491.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.5 1 1 0 1 1 1 0 CNH domain DUF1664 PF07889.12 EGO23493.1 - 0.013 15.5 7.3 0.35 10.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EGO23493.1 - 0.017 15.3 9.7 0.61 10.3 1.5 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 EGO23493.1 - 0.017 15.3 0.6 0.017 15.3 0.6 3.0 3 1 1 4 4 3 0 ABC transporter C-terminal domain LPP PF04728.13 EGO23493.1 - 0.03 14.7 2.2 0.76 10.2 0.4 3.0 2 1 0 2 2 2 0 Lipoprotein leucine-zipper JIP_LZII PF16471.5 EGO23493.1 - 0.051 13.7 1.4 0.051 13.7 1.4 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Reovirus_cap PF00979.17 EGO23493.1 - 0.07 12.3 0.8 0.89 8.6 0.2 2.1 2 0 0 2 2 2 0 Reovirus outer capsid protein, Sigma 3 ABC1 PF03109.16 EGO23493.1 - 0.084 13.0 0.0 0.36 11.0 0.0 2.1 1 1 0 2 2 2 0 ABC1 family MscS_porin PF12795.7 EGO23493.1 - 0.089 12.3 6.8 0.7 9.4 0.6 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Spectrin PF00435.21 EGO23493.1 - 0.12 12.9 8.4 0.92 10.0 1.9 2.7 1 1 1 2 2 2 0 Spectrin repeat YabA PF06156.13 EGO23493.1 - 0.12 13.0 10.4 0.17 12.5 2.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 EGO23493.1 - 0.17 12.4 14.8 0.16 12.4 2.1 2.4 1 1 0 2 2 2 0 Fez1 CALCOCO1 PF07888.11 EGO23493.1 - 0.25 10.2 14.9 0.42 9.4 14.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 EGO23493.1 - 0.25 11.4 16.4 1.7 8.6 5.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 EGO23493.1 - 0.39 10.7 6.6 1.2 9.1 3.1 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4472 PF14739.6 EGO23493.1 - 0.47 11.2 9.7 5.2 7.8 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Copper-fist PF00649.18 EGO23493.1 - 0.75 9.3 3.3 0.47 10.0 0.8 1.9 2 0 0 2 2 2 0 Copper fist DNA binding domain Tropomyosin_1 PF12718.7 EGO23493.1 - 0.96 9.6 13.8 0.093 12.9 3.6 2.4 1 1 0 2 2 2 0 Tropomyosin like Snapin_Pallidin PF14712.6 EGO23493.1 - 1.9 9.0 8.0 1.8 9.0 1.1 2.9 2 1 0 2 2 2 0 Snapin/Pallidin Csm1_N PF18504.1 EGO23493.1 - 2.2 8.7 8.1 1.2 9.6 0.3 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain ATG16 PF08614.11 EGO23493.1 - 4.3 7.5 17.8 0.065 13.5 3.4 2.8 2 1 2 4 4 3 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 EGO23493.1 - 5.7 6.7 11.0 8.7 6.1 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 EGO23493.1 - 7.6 7.0 7.4 10 6.6 0.6 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 EGO23493.1 - 9.9 6.3 12.1 14 5.8 2.5 3.8 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 RapA_C PF12137.8 EGO23495.1 - 0.2 10.6 4.3 0.21 10.6 4.3 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Plavaka PF18759.1 EGO23499.1 - 3.8e-132 440.4 0.0 5.1e-132 440.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 EGO23499.1 - 0.12 13.3 6.1 0.051 14.4 2.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger STE3 PF02076.15 EGO23503.1 - 4.1e-96 321.6 23.8 4.9e-96 321.3 23.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor RPAP1_C PF08620.10 EGO23504.1 - 7.3e-20 70.9 0.1 1.7e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGO23504.1 - 2e-10 40.3 2.0 5.7e-10 38.8 2.0 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal Atg14 PF10186.9 EGO23504.1 - 2.1 7.4 5.2 3.4 6.7 5.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COesterase PF00135.28 EGO23505.1 - 1.2e-94 318.1 0.0 4.9e-93 312.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO23505.1 - 0.00041 20.3 0.2 0.0022 17.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO23505.1 - 0.00079 19.0 0.1 0.0058 16.1 0.4 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family AAA PF00004.29 EGO23506.1 - 2.2e-39 134.9 0.0 4.6e-39 133.9 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO23506.1 - 2.8e-09 36.6 0.0 6.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGO23506.1 - 8.3e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO23506.1 - 1.3e-06 28.9 0.1 6.1e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGO23506.1 - 5.1e-06 26.5 0.2 9.6e-05 22.4 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGO23506.1 - 4.1e-05 23.6 0.0 8.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO23506.1 - 9.6e-05 22.7 0.1 0.004 17.4 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO23506.1 - 0.00016 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGO23506.1 - 0.00025 21.2 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGO23506.1 - 0.00033 20.1 0.1 0.002 17.6 0.1 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EGO23506.1 - 0.00047 19.6 0.0 1.7 8.0 0.0 2.9 2 1 1 3 3 3 2 Bacterial TniB protein AAA_18 PF13238.6 EGO23506.1 - 0.00061 20.3 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGO23506.1 - 0.00066 19.6 0.1 0.0042 17.0 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EGO23506.1 - 0.0011 18.6 0.1 0.073 12.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO23506.1 - 0.0015 18.9 0.0 0.0042 17.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TsaE PF02367.17 EGO23506.1 - 0.0021 18.0 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGO23506.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 EGO23506.1 - 0.0052 17.0 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGO23506.1 - 0.0053 16.5 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGO23506.1 - 0.006 16.5 0.1 0.013 15.4 0.1 1.6 2 0 0 2 2 1 1 NACHT domain TIP49 PF06068.13 EGO23506.1 - 0.0068 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 EGO23506.1 - 0.0077 16.0 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EGO23506.1 - 0.0092 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EGO23506.1 - 0.012 15.4 0.0 0.04 13.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGO23506.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Hydin_ADK PF17213.3 EGO23506.1 - 0.016 15.5 0.2 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 EGO23506.1 - 0.022 15.2 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGO23506.1 - 0.032 14.1 0.1 3.6 7.3 0.1 2.5 2 1 1 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGO23506.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EGO23506.1 - 0.049 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EGO23506.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EGO23506.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 EGO23506.1 - 0.067 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 EGO23506.1 - 0.077 12.3 0.0 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.11 EGO23506.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_lig_kinase PF08303.11 EGO23506.1 - 0.12 12.5 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain SKI PF01202.22 EGO23506.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase DUF815 PF05673.13 EGO23506.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sensor PF13796.6 EGO23507.1 - 0.0066 16.5 1.7 0.0096 16.0 1.7 1.2 1 0 0 1 1 1 1 Putative sensor ALG11_N PF15924.5 EGO23508.1 - 4e-89 298.2 0.1 7.1e-89 297.4 0.1 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGO23508.1 - 4.3e-23 81.7 0.0 6.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO23508.1 - 7.6e-11 42.6 0.0 3.1e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 STE3 PF02076.15 EGO23509.1 - 4.7e-92 308.3 23.3 5.9e-92 308.0 23.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Ycf9 PF01737.17 EGO23509.1 - 1.1 9.2 7.8 3.3 7.6 0.0 3.0 3 0 0 3 3 3 0 YCF9 RPAP1_N PF08621.10 EGO23511.1 - 1.4e-07 31.2 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 RPAP1-like, N-terminal SipA PF09052.10 EGO23511.1 - 0.03 13.9 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 SipA N-terminal domain MMADHC PF10229.9 EGO23511.1 - 0.047 13.4 0.0 0.048 13.4 0.0 1.0 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein zf-CCHC PF00098.23 EGO23512.1 - 6.8e-07 29.1 3.0 1.1e-06 28.4 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO23512.1 - 0.13 12.0 0.8 0.23 11.2 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO23512.1 - 0.18 11.8 3.0 0.33 10.9 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Sec3-PIP2_bind PF15277.6 EGO23513.1 - 0.053 13.6 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Defensin_5 PF18251.1 EGO23515.1 - 0.055 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Fungal defensin Copsin Retrotrans_gag PF03732.17 EGO23516.1 - 1.1e-06 28.8 3.3 2e-06 28.0 3.3 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO23516.1 - 0.27 11.4 0.7 0.44 10.7 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO23516.1 - 0.85 9.4 4.4 0.66 9.7 1.2 2.4 3 0 0 3 3 3 0 Zinc knuckle gag_pre-integrs PF13976.6 EGO23518.1 - 6.9e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF1771 PF08590.10 EGO23519.1 - 0.054 13.9 1.2 0.084 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_4 PF14392.6 EGO23519.1 - 0.065 13.0 1.6 0.1 12.4 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Plasmodium_Vir PF05795.11 EGO23519.1 - 0.07 12.5 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-C2H2_10 PF16588.5 EGO23519.1 - 0.11 12.2 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 EGO23519.1 - 1.6 8.6 4.7 1 9.2 0.4 2.8 3 0 0 3 3 3 0 Zinc knuckle STE3 PF02076.15 EGO23522.1 - 2.5e-47 161.5 13.4 2.9e-47 161.3 13.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor Ycf9 PF01737.17 EGO23522.1 - 8.6 6.3 14.3 1.7 8.6 0.2 2.9 3 0 0 3 3 3 0 YCF9 RPAP1_N PF08621.10 EGO23523.1 - 0.0042 16.8 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal STE3 PF02076.15 EGO23524.1 - 1.2e-06 27.9 1.0 1.2e-06 27.9 1.0 1.4 2 0 0 2 2 2 1 Pheromone A receptor STE3 PF02076.15 EGO23528.1 - 4.5e-93 311.6 19.5 5.2e-93 311.4 19.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4027 PF13219.6 EGO23528.1 - 1 9.3 0.1 1 9.3 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4027) DUF5592 PF17332.2 EGO23528.1 - 3.5 8.2 7.3 20 5.8 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5592) Sad1_UNC PF07738.13 EGO23530.1 - 7.9e-27 93.9 0.1 1.3e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal IER PF05760.12 EGO23530.1 - 6.3 7.0 10.5 0.3 11.3 3.8 1.9 2 0 0 2 2 2 0 Immediate early response protein (IER) ATP-synt_C PF00137.21 EGO23531.1 - 3.7e-33 113.7 34.9 6.3e-22 77.7 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF4096 PF13340.6 EGO23534.1 - 0.0036 17.5 1.2 0.0047 17.1 0.5 1.6 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) Phage_holin_2_3 PF16080.5 EGO23534.1 - 0.028 14.2 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF2254 PF10011.9 EGO23534.1 - 0.028 13.2 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) SPT_ssu-like PF11779.8 EGO23534.1 - 0.089 12.4 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Asp4 PF16996.5 EGO23534.1 - 0.095 12.5 0.8 0.19 11.5 0.8 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 Adeno_terminal PF02459.15 EGO23534.1 - 1 7.7 2.5 1.1 7.6 2.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein EGF_CA PF07645.15 EGO23536.1 - 0.044 14.0 3.8 0.06 13.6 3.8 1.2 1 0 0 1 1 1 0 Calcium-binding EGF domain Tetraspanin PF00335.20 EGO23539.1 - 4.9e-12 46.1 4.2 7.4e-12 45.5 4.2 1.3 1 0 0 1 1 1 1 Tetraspanin family DHHC PF01529.20 EGO23539.1 - 7.9 6.6 5.8 21 5.2 3.4 2.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase adh_short PF00106.25 EGO23540.1 - 5.5e-25 88.0 0.0 5.1e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23540.1 - 5.3e-13 49.1 0.0 1.5e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO23540.1 - 1.7e-07 31.3 0.1 2.7e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO23540.1 - 0.00019 20.9 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO23540.1 - 0.00022 20.8 0.0 0.00035 20.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EGO23540.1 - 0.0081 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGO23540.1 - 0.22 11.9 0.4 0.54 10.7 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EGO23541.1 - 5e-51 173.7 0.0 5.8e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO23541.1 - 3.1e-18 66.1 0.2 1.6e-14 54.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO23541.1 - 2e-16 60.1 0.1 1.8e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO23541.1 - 4.5e-06 26.1 0.0 5.7e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EGO23541.1 - 2.4e-05 24.1 0.0 0.00023 20.9 0.0 2.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO23541.1 - 0.00011 22.3 0.3 0.004 17.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGO23541.1 - 0.00019 20.6 4.9 0.005 16.0 0.1 3.8 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGO23541.1 - 0.00031 20.0 2.2 0.0031 16.7 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 EGO23541.1 - 0.00099 18.4 0.2 0.033 13.5 0.0 2.5 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EGO23541.1 - 0.0011 18.5 0.0 0.0066 15.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGO23541.1 - 0.0017 18.7 0.0 0.18 12.2 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 EGO23541.1 - 0.0069 15.1 1.5 0.042 12.5 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 EGO23541.1 - 0.0071 16.4 0.4 7.1 6.7 0.0 3.2 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EGO23541.1 - 0.0081 15.0 0.1 0.055 12.3 0.0 2.2 3 0 0 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.6 EGO23541.1 - 0.014 14.6 0.1 0.46 9.6 0.0 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 EGO23541.1 - 0.022 14.4 0.4 6.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EGO23541.1 - 0.036 14.7 0.0 2.1 9.0 0.0 2.7 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EGO23541.1 - 0.11 12.1 0.0 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HXXSHH PF07586.11 EGO23544.1 - 0.015 14.9 0.1 0.031 13.9 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) zf-C2HE PF16278.5 EGO23544.1 - 0.083 13.3 0.4 0.19 12.2 0.4 1.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF5053 PF16476.5 EGO23544.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) GSH_synth_ATP PF03917.17 EGO23546.1 - 6.6e-100 334.5 0.0 4.5e-73 246.2 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGO23546.1 - 4.7e-31 107.3 0.0 8.3e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Ank_2 PF12796.7 EGO23546.1 - 0.14 12.8 0.4 0.35 11.5 0.4 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) p450 PF00067.22 EGO23547.1 - 8.1e-44 150.1 0.0 1.2e-43 149.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 LTD PF00932.19 EGO23547.1 - 0.051 13.9 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain Complex1_51K PF01512.17 EGO23548.1 - 2.1e-32 112.1 0.0 2.6e-31 108.6 0.0 2.4 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGO23548.1 - 1.1e-26 92.7 0.4 4.1e-26 90.9 0.4 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region EHN PF06441.12 EGO23548.1 - 3.3e-14 53.2 0.0 6.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Helicase_C PF00271.31 EGO23548.1 - 6e-10 39.5 0.2 1.2e-09 38.5 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLBB PF10531.9 EGO23548.1 - 2.8e-06 27.1 0.0 1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 SLBB domain Abhydrolase_1 PF00561.20 EGO23548.1 - 1.7e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO23548.1 - 0.01 16.4 0.0 0.03 14.9 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family CENP-H PF05837.12 EGO23550.1 - 0.087 13.2 3.4 0.24 11.8 3.4 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Cyclin_N PF00134.23 EGO23551.1 - 5.4e-41 139.3 1.5 2.2e-40 137.4 0.5 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO23551.1 - 1.5e-21 76.7 0.0 3.7e-21 75.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF3314 PF11771.8 EGO23551.1 - 0.061 13.4 0.2 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) Plavaka PF18759.1 EGO23552.1 - 7.1e-46 156.9 0.0 1.2e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase APH PF01636.23 EGO23554.1 - 3.8e-07 30.3 0.0 0.00053 20.0 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO23554.1 - 2.9e-05 23.8 0.0 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Aldedh PF00171.22 EGO23554.1 - 0.032 12.8 0.0 0.049 12.1 0.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Pkinase_fungal PF17667.1 EGO23555.1 - 4e-30 104.9 0.0 5.2e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase AGH PF17558.2 EGO23555.1 - 0.097 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Androgenic gland hormone Cyclin_N PF00134.23 EGO23557.1 - 3.7e-36 123.7 0.2 6.6e-36 122.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Plavaka PF18759.1 EGO23558.1 - 5.6e-25 88.2 0.0 2.9e-16 59.6 0.0 3.2 1 1 1 2 2 2 2 Plavaka transposase zf-C2HC_2 PF13913.6 EGO23558.1 - 0.023 14.6 0.5 0.051 13.5 0.5 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Asp_protease_2 PF13650.6 EGO23559.1 - 0.00013 22.5 0.0 0.00023 21.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO23559.1 - 0.00028 21.4 0.0 0.0005 20.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO23559.1 - 0.05 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 EGO23560.1 - 4.1e-08 32.9 5.9 7.7e-08 32.1 5.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO23560.1 - 0.01 15.8 2.0 0.027 14.4 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO23560.1 - 0.029 14.6 1.7 0.033 14.5 0.0 1.9 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO23561.1 - 8.6e-07 28.8 1.3 8.9e-07 28.8 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO23561.1 - 4e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO23561.1 - 0.01 15.3 0.7 0.016 14.6 0.7 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO23561.1 - 0.15 11.8 3.5 0.19 11.4 3.5 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Plavaka PF18759.1 EGO23562.1 - 1e-17 64.4 0.0 1.8e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase zf-C2HC_2 PF13913.6 EGO23562.1 - 0.0086 16.0 0.5 0.019 14.9 0.5 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 EGO23562.1 - 0.091 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon Cyclin_C PF02984.19 EGO23563.1 - 1.2e-21 76.9 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EGO23563.1 - 1.2e-21 76.7 0.4 1.2e-20 73.5 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3314 PF11771.8 EGO23563.1 - 0.043 14.0 0.1 0.056 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) Pkinase_fungal PF17667.1 EGO23565.1 - 4.9e-29 101.3 0.0 6.4e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF3891 PF13030.6 EGO23566.1 - 0.056 13.2 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) CALCOCO1 PF07888.11 EGO23568.1 - 0.0024 16.8 0.5 0.0032 16.4 0.5 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 EGO23568.1 - 0.0094 16.2 1.1 0.034 14.5 0.8 1.9 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Transcrip_act PF04949.13 EGO23568.1 - 0.01 15.8 0.1 0.57 10.1 0.1 2.0 1 1 1 2 2 2 0 Transcriptional activator RP-C PF03428.13 EGO23568.1 - 0.014 15.1 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Replication protein C N-terminal domain DHR10 PF18595.1 EGO23568.1 - 0.014 15.4 1.2 0.02 14.9 1.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CHASE3 PF05227.13 EGO23568.1 - 0.016 15.1 0.9 0.036 14.0 0.9 1.5 1 1 0 1 1 1 0 CHASE3 domain Phage_HK97_TLTM PF06120.11 EGO23568.1 - 0.018 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Seryl_tRNA_N PF02403.22 EGO23568.1 - 0.023 14.9 0.4 0.039 14.2 0.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EGO23568.1 - 0.025 13.5 0.6 0.043 12.7 0.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SbcD_C PF12320.8 EGO23568.1 - 0.038 14.3 0.2 0.26 11.6 0.1 2.1 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain VHL_C PF17211.3 EGO23568.1 - 0.039 14.0 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 VHL box domain NPV_P10 PF05531.12 EGO23568.1 - 0.071 13.6 1.3 0.27 11.7 0.5 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein POP1 PF06978.11 EGO23569.1 - 3.6e-45 154.5 20.5 2.4e-26 93.0 1.7 3.0 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGO23569.1 - 8.4e-33 112.6 1.2 8.4e-33 112.6 1.2 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 EGO23569.1 - 0.00017 21.0 0.0 0.061 12.7 0.0 2.6 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGO23569.1 - 0.0021 18.0 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Receptor_2B4 PF11465.8 EGO23569.1 - 0.029 14.6 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Nbl1_Borealin_N PF10444.9 EGO23570.1 - 1.7e-14 53.2 0.0 4.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 EGO23570.1 - 0.0021 18.0 1.1 0.0021 18.0 1.1 3.8 4 1 0 4 4 4 2 Cell division cycle-associated protein 8 RP-C_C PF11800.8 EGO23570.1 - 2.2 8.3 7.9 1 9.4 3.4 2.3 2 1 0 2 2 2 0 Replication protein C C-terminal region 3Beta_HSD PF01073.19 EGO23571.1 - 1.8e-64 217.5 0.0 1.5e-58 198.0 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO23571.1 - 1.8e-30 106.2 0.1 2.7e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO23571.1 - 3.8e-17 62.7 0.1 4.1e-12 46.2 0.3 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO23571.1 - 6.4e-13 48.4 0.1 9.4e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGO23571.1 - 1.3e-11 44.2 0.1 4.8e-08 32.5 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGO23571.1 - 1.4e-10 41.3 0.0 2.8e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO23571.1 - 0.00024 20.4 1.8 0.0026 16.9 1.8 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EGO23571.1 - 0.026 14.8 0.2 0.05 13.9 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 EGO23571.1 - 0.043 13.7 0.3 0.1 12.5 0.3 1.7 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 EGO23571.1 - 0.12 12.0 0.5 0.49 9.9 0.5 1.9 1 1 0 1 1 1 0 NmrA-like family NBD_C PF17042.5 EGO23571.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain SUR7 PF06687.12 EGO23572.1 - 0.91 9.1 20.4 0.4 10.3 4.4 3.2 1 1 2 3 3 3 0 SUR7/PalI family DUF4395 PF14340.6 EGO23572.1 - 1.3 9.3 16.9 0.092 13.1 1.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4395) 3Beta_HSD PF01073.19 EGO23573.1 - 3e-24 85.5 0.0 5.5e-24 84.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO23573.1 - 6.3e-17 61.6 0.0 8e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 EGO23573.1 - 2e-14 53.7 0.0 5.3e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO23573.1 - 2.2e-06 27.3 0.0 0.00036 20.0 0.0 2.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO23573.1 - 5.5e-05 22.4 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO23573.1 - 0.00095 18.4 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGO23573.1 - 0.0015 18.5 0.0 0.0055 16.6 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO23573.1 - 0.0021 18.0 0.0 0.005 16.8 0.0 1.6 1 1 0 1 1 1 1 KR domain Elong_Iki1 PF10483.9 EGO23575.1 - 2.3e-09 37.2 0.2 3.1e-08 33.5 0.2 2.1 1 1 0 1 1 1 1 Elongator subunit Iki1 MPDZ_u10 PF16667.5 EGO23575.1 - 2.8 8.9 6.0 1.6 9.7 2.9 2.3 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Usp PF00582.26 EGO23576.1 - 2.1e-21 76.9 1.2 4.6e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.6 EGO23576.1 - 0.0048 17.0 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PRANC PF09372.10 EGO23578.1 - 0.0056 17.0 0.6 0.34 11.2 0.1 2.3 2 0 0 2 2 2 2 PRANC domain RPAP3_C PF13877.6 EGO23579.1 - 5.8e-06 26.8 0.0 6.2e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Peptidase_M20 PF01546.28 EGO23581.1 - 8.5e-27 94.2 0.0 1.7e-26 93.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO23581.1 - 5.3e-11 42.4 0.0 9.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 EGO23581.1 - 1e-09 38.8 10.7 0.57 11.1 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 EGO23581.1 - 0.0026 17.1 0.0 0.3 10.4 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EGO23581.1 - 0.0058 15.3 0.2 0.0098 14.6 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGO23581.1 - 0.02 15.2 0.0 0.76 10.1 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGO23581.1 - 0.12 12.9 0.0 23 5.6 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain DUF2220 PF09983.9 EGO23582.1 - 0.16 11.4 0.4 0.22 10.9 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) DAHP_synth_1 PF00793.20 EGO23583.1 - 2.4e-98 328.4 0.0 3.2e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MtrF PF09472.10 EGO23583.1 - 0.15 11.5 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Exonuc_VII_S PF02609.16 EGO23583.1 - 2.2 8.4 6.1 8.6 6.5 0.1 3.4 4 0 0 4 4 4 0 Exonuclease VII small subunit zf-Tim10_DDP PF02953.15 EGO23584.1 - 4e-19 68.0 7.8 5.7e-19 67.5 7.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 EGO23584.1 - 0.051 13.1 1.4 0.06 12.9 1.4 1.0 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Tam41_Mmp37 PF09139.11 EGO23584.1 - 0.083 12.3 0.1 0.083 12.3 0.1 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial AhpC-TSA PF00578.21 EGO23586.1 - 1.8e-29 102.2 0.0 2.3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO23586.1 - 6.6e-19 68.1 0.0 9.2e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGO23586.1 - 5.6e-05 23.2 0.0 8.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 EGO23586.1 - 0.042 14.2 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Acetyltransf_3 PF13302.7 EGO23587.1 - 1.4e-15 58.2 0.0 1.6e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO23587.1 - 6.8e-13 48.9 0.0 8.4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO23587.1 - 8.7e-06 25.7 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO23587.1 - 1.3e-05 25.5 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO23587.1 - 2.1e-05 24.7 0.0 2.4e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO23587.1 - 0.00062 19.7 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EGO23587.1 - 0.00079 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TRAP_alpha PF03896.16 EGO23589.1 - 0.076 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 EGO23591.1 - 1.6e-50 172.0 0.0 1.9e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23591.1 - 6.6e-27 94.4 0.1 6.6e-26 91.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGO23591.1 - 0.00069 19.3 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGO23591.1 - 0.0013 18.2 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO23591.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO23591.1 - 0.068 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGO23591.1 - 0.074 12.7 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NMO PF03060.15 EGO23592.1 - 6.7e-56 190.1 0.2 4.7e-55 187.3 0.2 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO23592.1 - 1.8e-11 43.7 0.2 3e-05 23.2 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO23592.1 - 0.0012 18.0 0.4 0.0019 17.3 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 EGO23592.1 - 0.043 13.0 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 EGO23592.1 - 0.049 12.8 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.17 EGO23592.1 - 0.07 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase LRR_4 PF12799.7 EGO23593.1 - 0.0034 17.7 1.6 1.7 9.1 0.2 3.7 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) Roughex PF06020.11 EGO23593.1 - 0.028 13.5 0.6 0.037 13.1 0.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF2205 PF10224.9 EGO23594.1 - 1.8e-10 40.6 0.2 2e-10 40.5 0.2 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 EGO23594.1 - 0.022 15.4 0.3 0.024 15.2 0.3 1.1 1 0 0 1 1 1 0 Initiation control protein YabA KASH_CCD PF14662.6 EGO23594.1 - 0.036 13.9 0.3 0.04 13.7 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 EGO23594.1 - 0.094 12.5 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator RPN13_C PF16550.5 EGO23595.1 - 3e-30 104.7 0.0 5.7e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 EGO23595.1 - 6.1e-28 97.2 0.0 8.6e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Arf PF00025.21 EGO23596.1 - 6.2e-35 120.2 0.0 7.1e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGO23596.1 - 1.4e-17 63.8 0.0 1.7e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO23596.1 - 5e-15 55.8 0.1 6.4e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGO23596.1 - 2.4e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGO23596.1 - 4.2e-08 32.8 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO23596.1 - 1.9e-06 28.0 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGO23596.1 - 1.8e-05 24.1 0.6 0.00012 21.3 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 EGO23596.1 - 0.0043 16.6 0.0 0.0091 15.5 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGO23596.1 - 0.016 15.2 0.7 0.56 10.2 0.8 2.1 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 EGO23596.1 - 0.078 12.7 0.3 6.9 6.4 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EGO23596.1 - 0.12 12.3 0.0 0.72 9.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EGO23596.1 - 0.16 12.3 0.1 11 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pet127 PF08634.10 EGO23597.1 - 1.5e-106 355.8 0.0 3.7e-106 354.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein Pet127 PET117 PF15786.5 EGO23597.1 - 0.27 11.5 1.6 0.64 10.3 1.6 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial MFS_1 PF07690.16 EGO23598.1 - 5.8e-15 55.1 33.9 5.8e-15 55.1 33.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO23598.1 - 3.4e-13 49.6 4.9 3.4e-13 49.6 4.9 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 F-box-like PF12937.7 EGO23599.1 - 0.0005 19.9 2.9 0.0016 18.3 2.9 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGO23599.1 - 0.00066 20.0 2.6 18 5.9 0.0 5.4 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) Ribosomal_S19e PF01090.19 EGO23600.1 - 3.9e-58 195.0 0.0 4.5e-58 194.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Acetyltransf_3 PF13302.7 EGO23601.1 - 6.3e-14 52.8 0.1 1e-13 52.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO23601.1 - 1.7e-11 44.4 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPP_enzyme_N PF02776.18 EGO23602.1 - 3.6e-38 130.9 0.1 6.2e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO23602.1 - 1.2e-16 60.7 0.0 2.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGO23602.1 - 1.5e-15 57.3 0.0 4.4e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain STE3 PF02076.15 EGO23603.1 - 1.4e-91 306.7 16.5 1.7e-91 306.5 16.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF350 PF03994.14 EGO23603.1 - 0.24 11.6 8.1 1.2 9.4 0.0 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF350) DUF3561 PF12084.8 EGO23603.1 - 1.1 9.3 8.9 0.055 13.5 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3561) STE3 PF02076.15 EGO23605.1 - 3.1e-90 302.3 23.3 3.7e-90 302.1 23.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor Helicase_C_2 PF13307.6 EGO23606.1 - 6.2e-19 68.8 0.4 6.9e-19 68.7 0.4 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain DUF4523 PF15023.6 EGO23606.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Trypsin_2 PF13365.6 EGO23607.1 - 0.037 14.9 0.0 0.69 10.8 0.0 2.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 EGO23607.1 - 0.058 12.6 1.0 0.28 10.3 0.6 1.9 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF3127 PF11325.8 EGO23607.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) DUF4398 PF14346.6 EGO23607.1 - 0.18 12.4 0.1 0.32 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Helicase_C_2 PF13307.6 EGO23609.1 - 1e-53 182.0 0.0 3e-53 180.5 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGO23609.1 - 3.7e-44 150.4 0.0 7.6e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.16 EGO23609.1 - 0.0012 18.4 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 EGO23609.1 - 0.0072 16.3 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO23609.1 - 0.0075 16.0 0.1 0.1 12.3 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO23609.1 - 0.022 15.0 0.0 8.3 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain GATase_3 PF07685.14 EGO23609.1 - 0.095 12.3 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain T2SSE PF00437.20 EGO23609.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DHR10 PF18595.1 EGO23609.1 - 2.7 8.1 16.1 3.3 7.8 7.7 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DivIC PF04977.15 EGO23609.1 - 2.8 7.8 6.2 13 5.6 6.2 2.1 1 0 0 1 1 1 0 Septum formation initiator SOGA PF11365.8 EGO23609.1 - 9.6 7.4 9.2 66 4.7 0.1 3.2 3 0 0 3 3 3 0 Protein SOGA Hpt PF01627.23 EGO23610.1 - 6.2e-10 39.2 0.0 8.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain ATP-grasp_6 PF18419.1 EGO23610.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain CoA_transf_3 PF02515.17 EGO23611.1 - 4.3e-127 424.2 0.0 4.9e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Na_Ca_ex PF01699.24 EGO23613.1 - 8.8e-21 74.4 34.3 2.9e-11 43.6 12.7 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein YccF PF03733.13 EGO23613.1 - 2.1e-13 50.7 10.5 2.1e-13 50.7 10.5 4.0 3 0 0 3 3 3 2 Inner membrane component domain MMS1_N PF10433.9 EGO23614.1 - 7.7e-60 202.9 0.0 3.1e-59 200.9 0.0 2.0 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGO23614.1 - 2.7e-46 158.4 0.1 6.7e-46 157.1 0.1 1.7 1 0 0 1 1 1 1 CPSF A subunit region CBFD_NFYB_HMF PF00808.23 EGO23615.1 - 2.9e-15 56.3 0.8 4.5e-15 55.7 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO23615.1 - 1.7e-09 38.1 2.6 2.7e-09 37.5 2.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 EGO23615.1 - 0.015 15.5 0.1 0.035 14.3 0.1 1.6 1 1 1 2 2 2 0 CENP-W protein Bromo_TP PF07524.13 EGO23615.1 - 0.027 14.5 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF3654 PF12376.8 EGO23615.1 - 0.16 12.2 1.5 0.29 11.3 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3654) HIT PF01230.23 EGO23616.1 - 2.5e-21 76.3 0.2 3.7e-21 75.7 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO23616.1 - 3.1e-13 50.2 0.0 4.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGO23616.1 - 3.2e-05 23.8 0.1 4.8e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 She9_MDM33 PF05546.11 EGO23617.1 - 4.4e-77 258.4 10.7 7e-77 257.7 10.7 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family DUF2371 PF10177.9 EGO23617.1 - 0.021 15.0 0.0 0.056 13.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) MbeB_N PF04837.12 EGO23617.1 - 0.061 13.6 4.7 4.4 7.7 0.3 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region TMF_DNA_bd PF12329.8 EGO23617.1 - 2.6 8.1 6.7 1.3 9.1 3.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 EGO23617.1 - 3.7 7.9 9.1 3.3 8.0 6.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 EGO23617.1 - 6.3 7.2 14.6 0.27 11.6 0.8 3.0 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.14 EGO23617.1 - 7.8 6.2 10.6 4.1 7.2 0.4 3.6 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain FAD_binding_1 PF00667.20 EGO23618.1 - 1.6e-56 191.3 0.0 1.1e-55 188.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGO23618.1 - 8.8e-29 100.6 0.3 1.7e-28 99.6 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGO23618.1 - 3e-20 72.9 0.0 1.3e-19 70.8 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Yae1_N PF09811.9 EGO23620.1 - 4e-11 42.4 0.4 7.4e-11 41.6 0.4 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal UAA PF08449.11 EGO23621.1 - 7.9e-43 146.8 9.4 7.9e-43 146.8 9.4 1.8 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 EGO23621.1 - 5e-10 39.7 19.3 3.2e-07 30.6 8.1 4.0 4 1 0 4 4 4 2 EamA-like transporter family CRT-like PF08627.10 EGO23621.1 - 0.00081 18.4 5.0 0.018 14.0 0.6 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EGO23621.1 - 0.0044 16.4 2.2 0.39 10.0 0.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EGO23621.1 - 0.0078 15.4 2.8 0.82 8.8 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter Connexin PF00029.19 EGO23621.1 - 0.07 12.9 0.7 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Connexin cobW PF02492.19 EGO23622.1 - 2.3e-46 157.6 0.1 3.5e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGO23622.1 - 1.2e-07 31.6 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EGO23622.1 - 4.2e-06 26.4 0.0 0.0072 15.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO23622.1 - 0.00011 22.3 0.0 0.00028 21.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO23622.1 - 0.00013 21.9 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 EGO23622.1 - 0.00073 18.6 0.3 0.11 11.5 0.0 3.4 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EGO23622.1 - 0.0034 17.6 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO23622.1 - 0.0038 17.5 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 EGO23622.1 - 0.0096 15.4 0.2 1.3 8.4 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 EGO23622.1 - 0.047 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 EGO23622.1 - 0.051 14.1 0.1 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EGO23622.1 - 0.056 13.3 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 EGO23622.1 - 0.071 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 EGO23622.1 - 0.094 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EGO23622.1 - 0.17 11.6 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EGO23623.1 - 4.8e-57 192.6 0.0 8.4e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGO23623.1 - 1.5e-15 57.0 0.0 3.6e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGO23623.1 - 2.4e-08 34.0 0.0 5.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGO23623.1 - 8.6e-05 22.6 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGO23623.1 - 0.0014 18.9 0.0 0.0044 17.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RasGEF PF00617.19 EGO23624.1 - 7.9e-58 195.6 0.4 1.6e-57 194.6 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO23624.1 - 5.7e-21 74.7 0.1 1.6e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif EcoEI_R_C PF08463.10 EGO23624.1 - 0.041 14.0 0.3 0.1 12.7 0.3 1.6 1 0 0 1 1 1 0 EcoEI R protein C-terminal Pkinase PF00069.25 EGO23625.1 - 2.3e-63 214.0 0.0 5.8e-63 212.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23625.1 - 6.2e-37 127.3 0.0 1e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EGO23625.1 - 8.7e-23 80.2 19.2 4.3e-14 52.4 5.1 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EGO23625.1 - 1e-19 70.1 28.7 6.1e-12 45.2 9.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EGO23625.1 - 2e-10 41.2 2.4 3.6e-10 40.4 0.7 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EGO23625.1 - 2.3e-07 31.0 0.0 4.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 EGO23625.1 - 0.0045 16.0 0.1 0.0081 15.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO23625.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.16 EGO23625.1 - 0.4 11.0 22.3 0.57 10.5 7.3 2.6 2 0 0 2 2 2 0 C1 domain THOC7 PF05615.13 EGO23625.1 - 0.6 10.4 10.6 4.8 7.5 2.5 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 Endosulfine PF04667.17 EGO23627.1 - 4.6e-28 97.2 0.1 6.4e-28 96.7 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.16 EGO23628.1 - 5.5e-34 117.4 0.9 6.8e-34 117.1 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_3 PF14582.6 EGO23628.1 - 0.075 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily NUDIX PF00293.28 EGO23629.1 - 1.4e-12 47.7 0.2 8.9e-12 45.2 0.0 2.1 1 1 2 3 3 3 1 NUDIX domain CwfJ_C_2 PF04676.14 EGO23630.1 - 4e-37 127.1 0.5 6.2e-35 120.0 0.0 2.7 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EGO23630.1 - 1.3e-30 105.8 0.0 1.8e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 HpcH_HpaI PF03328.14 EGO23631.1 - 6.7e-43 146.4 0.0 1.6e-42 145.1 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGO23631.1 - 4.1e-11 42.6 0.1 1.6e-07 30.8 0.1 2.4 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold HA2 PF04408.23 EGO23632.1 - 1.4e-22 80.0 0.0 2.6e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO23632.1 - 7.9e-19 67.8 0.3 1.6e-18 66.9 0.3 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold NTP_transf_9 PF04248.12 EGO23633.1 - 1.5e-32 111.3 1.3 1.6e-32 111.2 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Mito_carr PF00153.27 EGO23634.1 - 1.1e-73 243.2 1.1 1.1e-25 89.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 EGO23634.1 - 0.088 13.0 0.1 35 4.6 0.0 3.2 3 0 0 3 3 3 0 PrcB C-terminal Serine_protease PF18405.1 EGO23634.1 - 3 6.9 4.8 31 3.6 0.0 3.8 3 2 1 5 5 5 0 Gammaproteobacterial serine protease DUF3328 PF11807.8 EGO23635.1 - 0.12 12.2 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Phage_holin_3_6 PF07332.11 EGO23635.1 - 0.12 12.4 0.5 0.23 11.5 0.1 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_M56 PF05569.11 EGO23635.1 - 0.26 10.4 0.2 0.39 9.9 0.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 AMP-binding PF00501.28 EGO23637.1 - 4e-68 230.0 0.0 5.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO23637.1 - 1.5e-15 57.9 0.6 5e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGO23638.1 - 3.9e-68 230.0 0.0 1.6e-38 132.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGO23638.1 - 2.3e-14 54.1 0.3 5.8e-14 52.8 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_C97 PF05903.14 EGO23639.1 - 4.7e-41 140.1 0.0 8.7e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 EGO23639.1 - 2.8e-36 125.2 0.7 4.2e-36 124.6 0.7 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 EGO23639.1 - 2.2e-15 56.5 0.0 4.6e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGO23639.1 - 5.6e-06 26.8 0.0 2.9e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGO23639.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGO23639.1 - 0.0096 15.6 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 1 Redoxin HEAT_EZ PF13513.6 EGO23639.1 - 0.016 15.7 0.1 0.046 14.2 0.1 1.9 1 0 0 1 1 1 0 HEAT-like repeat Carn_acyltransf PF00755.20 EGO23640.1 - 1.6e-190 634.7 0.0 1.9e-190 634.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fungal_trans PF04082.18 EGO23642.1 - 3.9e-12 45.8 1.2 7.9e-12 44.8 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3399 PF11879.8 EGO23642.1 - 0.0055 17.0 0.2 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) CAF1 PF04857.20 EGO23643.1 - 3.9e-21 75.5 0.6 1.7e-11 43.9 0.0 2.8 1 1 0 2 2 2 2 CAF1 family ribonuclease FCH PF00611.23 EGO23646.1 - 8e-15 54.9 0.0 1.6e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DPBB_1 PF03330.18 EGO23648.1 - 1.8e-05 24.9 0.2 5.7e-05 23.3 0.2 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGO23648.1 - 0.0026 17.6 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Barwin family GGGtGRT PF14057.6 EGO23648.1 - 0.085 11.8 0.1 0.089 11.7 0.1 1.1 1 0 0 1 1 1 0 GGGtGRT protein Phage_term_smal PF05944.12 EGO23649.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage small terminase subunit Band_7 PF01145.25 EGO23650.1 - 3.8e-25 88.9 2.9 9.6e-25 87.6 2.9 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family F-box-like PF12937.7 EGO23651.1 - 0.0082 16.0 0.2 0.025 14.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO23651.1 - 0.016 15.1 3.5 0.028 14.3 0.1 2.9 3 0 0 3 3 3 0 F-box domain HD_5 PF13487.6 EGO23651.1 - 0.073 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 HD domain Glyco_hydro_49 PF03718.13 EGO23652.1 - 0.098 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 WW PF00397.26 EGO23653.1 - 0.069 13.3 1.1 0.26 11.4 0.1 2.4 2 0 0 2 2 2 0 WW domain MASE3 PF17159.4 EGO23653.1 - 0.18 11.4 3.1 0.21 11.2 1.6 1.7 1 1 1 2 2 2 0 Membrane-associated sensor domain Ost5 PF05251.12 EGO23653.1 - 0.23 11.7 6.0 1.4 9.3 0.6 2.5 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DLH PF01738.18 EGO23654.1 - 1.8e-16 60.4 0.0 7.4e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGO23654.1 - 0.0008 19.1 0.0 0.002 17.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO23654.1 - 0.0049 17.5 0.0 0.01 16.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_permease_2 PF13520.6 EGO23655.1 - 4e-27 95.1 30.1 7.7e-18 64.5 11.9 2.0 2 0 0 2 2 2 2 Amino acid permease DDE_1 PF03184.19 EGO23656.1 - 1e-13 51.3 0.0 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Trehalase_Ca-bi PF07492.11 EGO23656.1 - 0.05 13.3 2.6 0.1 12.3 2.6 1.5 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain SAP PF02037.27 EGO23656.1 - 0.092 12.5 0.1 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 SAP domain RP-C_C PF11800.8 EGO23656.1 - 3.3 7.7 9.7 0.7 10.0 5.0 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region FAM76 PF16046.5 EGO23657.1 - 0.014 14.8 5.5 0.024 14.0 5.5 1.3 1 0 0 1 1 1 0 FAM76 protein NES_C_h PF18208.1 EGO23657.1 - 0.046 14.0 0.8 0.046 14.0 0.8 1.9 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain CENP-F_leu_zip PF10473.9 EGO23657.1 - 0.068 13.2 10.4 0.39 10.7 10.4 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hema_HEFG PF02710.14 EGO23657.1 - 0.097 12.9 0.9 0.22 11.7 0.9 1.6 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HAUS-augmin3 PF14932.6 EGO23657.1 - 0.41 10.2 13.1 0.03 13.9 8.1 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 PDDEXK_6 PF04720.12 EGO23657.1 - 0.91 9.4 7.5 0.062 13.2 2.2 1.7 2 0 0 2 2 2 0 PDDEXK-like family of unknown function BORCS7 PF16088.5 EGO23657.1 - 1.3 9.3 12.3 5.4 7.3 4.5 2.4 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 Mod_r PF07200.13 EGO23657.1 - 1.3 9.1 15.1 0.21 11.7 10.8 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMPIT PF07851.13 EGO23657.1 - 1.4 8.1 6.6 2 7.6 6.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 EGO23657.1 - 1.7 8.8 10.9 2.3 8.4 9.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 EGO23657.1 - 3.9 7.5 14.7 0.27 11.3 9.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KELK PF15796.5 EGO23657.1 - 4.1 7.9 9.5 1.4 9.4 2.5 2.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 EGO23657.1 - 4.2 7.4 9.0 2.1 8.4 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 EGO23657.1 - 5.6 7.6 8.9 1.1 9.9 5.1 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CC2-LZ PF16516.5 EGO23657.1 - 6.4 7.2 14.4 0.6 10.5 9.6 1.7 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Nnf1 PF03980.14 EGO23657.1 - 7.4 7.0 13.5 0.47 10.8 0.8 2.8 2 1 1 3 3 3 0 Nnf1 ATG101 PF07855.12 EGO23658.1 - 0.062 13.3 0.1 0.063 13.3 0.1 1.0 1 0 0 1 1 1 0 Autophagy-related protein 101 Pkinase PF00069.25 EGO23662.1 - 6.1e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23662.1 - 3.5e-06 26.5 0.0 1.4e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO23662.1 - 0.0021 16.9 0.1 0.0039 16.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Ribosomal_S19e PF01090.19 EGO23662.1 - 0.01 15.5 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S19e FA_desaturase PF00487.24 EGO23663.1 - 5.1e-22 78.9 23.6 5.1e-22 78.9 23.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EGO23663.1 - 0.012 15.9 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) D123 PF07065.14 EGO23664.1 - 1.7e-07 30.7 0.0 1.9e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 D123 EzrA PF06160.12 EGO23665.1 - 0.0081 14.4 4.5 0.014 13.6 4.5 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 EGO23665.1 - 0.009 16.2 8.5 0.48 10.6 1.5 2.7 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EGO23665.1 - 0.014 15.4 7.0 0.59 10.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EGO23665.1 - 0.051 14.0 14.5 0.18 12.2 1.3 2.5 2 1 1 3 3 2 0 Fez1 LPP PF04728.13 EGO23665.1 - 0.052 13.9 0.5 5 7.6 0.0 3.2 2 1 1 3 3 3 0 Lipoprotein leucine-zipper TSC22 PF01166.18 EGO23665.1 - 0.056 13.8 2.1 0.84 10.0 0.2 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 EGO23665.1 - 0.064 13.9 8.9 0.2 12.3 1.5 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Reovirus_cap PF00979.17 EGO23665.1 - 0.066 12.4 0.4 1.5 7.9 0.1 2.1 2 0 0 2 2 2 0 Reovirus outer capsid protein, Sigma 3 ABC1 PF03109.16 EGO23665.1 - 0.072 13.3 0.0 0.4 10.9 0.0 2.2 1 1 0 2 2 2 0 ABC1 family ATG16 PF08614.11 EGO23665.1 - 0.085 13.1 11.8 0.049 13.9 2.4 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1866 PF08952.11 EGO23665.1 - 0.13 12.1 0.8 0.25 11.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Tropomyosin_1 PF12718.7 EGO23665.1 - 0.16 12.2 13.3 0.077 13.2 3.6 2.5 1 1 1 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 EGO23665.1 - 0.17 12.1 6.8 0.22 11.8 1.2 3.6 3 1 1 4 4 4 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 EGO23665.1 - 0.4 10.7 14.7 3.2 7.8 2.3 2.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 EGO23665.1 - 0.44 10.7 5.3 0.36 11.0 1.0 2.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Spectrin PF00435.21 EGO23665.1 - 0.52 10.8 7.6 2.4 8.7 1.9 3.0 1 1 1 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 EGO23665.1 - 0.6 10.2 6.9 0.66 10.0 1.1 3.1 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Copper-fist PF00649.18 EGO23665.1 - 0.75 9.3 3.7 0.45 10.1 1.0 2.0 2 0 0 2 2 2 0 Copper fist DNA binding domain Csm1_N PF18504.1 EGO23665.1 - 0.99 9.8 7.3 0.88 9.9 0.4 3.5 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF4472 PF14739.6 EGO23665.1 - 2.9 8.7 11.9 4.4 8.1 1.1 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) TMF_DNA_bd PF12329.8 EGO23665.1 - 5.3 7.1 8.2 8.8 6.4 0.6 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Gal4_dimer PF03902.13 EGO23665.1 - 6.9 6.9 7.2 1.1 9.5 1.2 2.7 2 1 1 3 3 3 0 Gal4-like dimerisation domain WD40 PF00400.32 EGO23666.1 - 2.3e-12 47.2 15.9 9.1e-08 32.7 0.1 5.8 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO23666.1 - 2.8e-10 40.3 0.3 0.0098 16.2 0.0 4.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO23666.1 - 0.05 12.5 0.0 0.25 10.3 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 EGO23666.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 CNH domain LapA_dom PF06305.11 EGO23666.1 - 0.14 12.0 1.0 0.26 11.1 1.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain WD40_like PF17005.5 EGO23666.1 - 0.21 10.9 0.0 0.82 8.9 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Exo_endo_phos PF03372.23 EGO23670.1 - 0.00025 20.7 0.2 0.0011 18.5 0.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0160 PF03690.13 EGO23671.1 - 1.5e-134 448.6 0.0 1.8e-134 448.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) dTDP_sugar_isom PF00908.17 EGO23671.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase DDE_3 PF13358.6 EGO23674.1 - 7.2e-07 29.1 0.2 1.5e-06 28.0 0.1 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease Mpv17_PMP22 PF04117.12 EGO23674.1 - 0.038 14.2 0.6 0.26 11.6 0.1 2.1 2 0 0 2 2 2 0 Mpv17 / PMP22 family DUF3684 PF12449.8 EGO23675.1 - 2.8e-23 81.8 0.0 3.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) MAGE_N PF12440.8 EGO23675.1 - 0.08 13.6 2.8 0.18 12.5 2.8 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal HMMR_C PF15908.5 EGO23675.1 - 0.18 12.1 0.6 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Transket_pyr PF02779.24 EGO23676.1 - 5e-66 221.7 0.0 7.6e-66 221.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGO23676.1 - 1.9e-59 201.1 0.0 2.9e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGO23676.1 - 8.7e-53 178.1 0.0 1.5e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGO23676.1 - 4.1e-18 64.7 0.9 8.5e-18 63.7 0.9 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus zf-C2H2 PF00096.26 EGO23679.1 - 0.0074 16.7 0.4 0.014 15.8 0.1 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type Nipped-B_C PF12830.7 EGO23681.1 - 3.8e-52 177.0 1.5 3.8e-52 177.0 1.5 2.5 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EGO23681.1 - 4.1e-12 46.1 0.2 4.1e-12 46.1 0.2 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EGO23681.1 - 1.3e-05 25.0 0.3 1.1 9.7 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat PMC2NT PF08066.12 EGO23681.1 - 0.0047 17.6 3.1 3.9 8.2 0.1 3.7 2 0 0 2 2 2 2 PMC2NT (NUC016) domain SIL1 PF16782.5 EGO23681.1 - 0.011 15.0 0.2 0.011 15.0 0.2 2.0 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 Cnd1 PF12717.7 EGO23681.1 - 0.044 13.8 0.9 0.16 12.0 0.1 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGO23681.1 - 0.054 14.0 2.3 46 4.7 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 EGO23681.1 - 0.055 13.9 3.6 0.19 12.1 0.6 3.6 3 1 0 3 3 3 0 HEAT repeats HA2 PF04408.23 EGO23683.1 - 6.2e-21 74.7 0.1 1.3e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGO23683.1 - 1.7e-15 57.3 0.0 5.1e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGO23683.1 - 2.1e-06 28.0 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGO23683.1 - 4.6e-06 26.5 0.2 1.2e-05 25.2 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO23683.1 - 4.6e-06 26.9 0.0 9.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO23683.1 - 0.0053 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGO23683.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EGO23683.1 - 0.021 15.1 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGO23683.1 - 0.056 12.9 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 EGO23683.1 - 0.067 13.2 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EGO23683.1 - 0.072 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RIBIOP_C PF04950.12 EGO23684.1 - 3e-12 46.6 0.0 3.1e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal CIA30 PF08547.12 EGO23684.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) RIBIOP_C PF04950.12 EGO23685.1 - 3.3e-06 26.8 0.2 4.8e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DUF3015 PF11220.8 EGO23685.1 - 0.013 15.4 0.1 0.07 13.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) Cep57_MT_bd PF06657.13 EGO23686.1 - 1.5e-25 89.4 0.1 1.5e-25 89.4 0.1 3.0 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EGO23686.1 - 1.5e-09 37.8 7.4 1.5e-09 37.8 7.4 2.6 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 EGO23686.1 - 0.0027 17.7 5.9 0.0067 16.4 1.0 3.4 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.5 EGO23686.1 - 0.2 11.1 7.8 1.4 8.3 7.8 2.2 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EGO23686.1 - 0.38 9.6 10.4 0.46 9.3 7.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 EGO23686.1 - 0.67 8.9 3.9 0.32 9.9 1.2 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 EGO23686.1 - 5.7 7.3 9.6 7.1 7.0 7.7 2.1 1 1 1 2 2 2 0 Fez1 CorA PF01544.18 EGO23686.1 - 6.1 6.1 7.4 0.7 9.2 2.7 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 EGO23686.1 - 6.2 6.9 16.3 0.83 9.7 10.7 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 EGO23686.1 - 7 7.3 12.5 0.2 12.3 3.5 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 EGO23686.1 - 9.9 6.6 8.2 7.4 7.0 4.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) EHN PF06441.12 EGO23687.1 - 1.1e-30 106.2 0.3 6.9e-30 103.6 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EGO23687.1 - 1.1e-08 35.0 0.1 2.1e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO23687.1 - 1.9e-06 28.7 9.1 5.5e-06 27.1 9.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4190 PF13828.6 EGO23688.1 - 0.14 11.9 1.0 0.27 11.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Herpes_gE PF02480.16 EGO23688.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD99L2 PF12301.8 EGO23688.1 - 0.47 10.7 1.7 0.97 9.7 1.7 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 Ribosomal_L23eN PF03939.13 EGO23689.1 - 8.7e-23 80.3 8.9 8.7e-23 80.3 8.9 2.4 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGO23689.1 - 2.3e-15 56.7 3.3 2.3e-15 56.7 3.3 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 EGO23689.1 - 0.00065 20.0 0.2 0.00086 19.6 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5451) ASL_C PF08328.11 EGO23689.1 - 0.016 15.3 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal ADH_N PF08240.12 EGO23690.1 - 2.2e-25 88.7 0.4 3.6e-25 88.0 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO23690.1 - 2.2e-09 37.4 0.0 4.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNA_ligase_A_M PF01068.21 EGO23690.1 - 0.046 13.4 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain SMC_N PF02463.19 EGO23691.1 - 3.9e-69 232.4 1.4 5.2e-69 232.0 1.4 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGO23691.1 - 3.5e-27 95.0 0.0 1.2e-26 93.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGO23691.1 - 1.9e-16 60.8 4.9 1.7e-07 31.4 3.8 3.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGO23691.1 - 5.4e-15 56.0 24.8 4.6e-09 36.5 9.4 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGO23691.1 - 7.5e-09 36.4 42.0 7.5e-09 36.4 42.0 6.4 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 EGO23691.1 - 0.0081 16.7 18.6 0.1 13.1 0.8 5.4 3 2 1 4 4 4 2 ABC transporter Tropomyosin_1 PF12718.7 EGO23691.1 - 0.011 15.9 1.7 0.011 15.9 1.7 7.9 3 3 5 9 9 9 0 Tropomyosin like AAA_29 PF13555.6 EGO23691.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGO23691.1 - 0.17 11.2 4.7 0.27 10.5 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF87 PF01935.17 EGO23691.1 - 0.33 11.0 0.0 0.33 11.0 0.0 5.7 4 2 2 6 6 6 0 Helicase HerA, central domain RasGEF PF00617.19 EGO23692.1 - 1.9e-53 181.3 2.2 2.4e-53 180.9 1.4 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGO23692.1 - 9e-20 70.9 0.1 2.3e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RRM_1 PF00076.22 EGO23693.1 - 2.3e-07 30.6 0.0 4.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO23693.1 - 0.00049 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EGO23693.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGO23693.1 - 0.12 12.2 0.1 3 7.7 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif BTB_2 PF02214.22 EGO23693.1 - 0.13 12.7 0.1 6.1 7.3 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain PriX PF18689.1 EGO23693.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Primase X GAGE PF05831.11 EGO23693.1 - 3.8 8.1 11.2 1 9.9 7.7 1.8 2 0 0 2 2 2 0 GAGE protein Glyco_hydro_28 PF00295.17 EGO23694.1 - 2e-44 152.0 9.2 2.7e-44 151.6 9.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Methyltransf_31 PF13847.6 EGO23695.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO23695.1 - 4.7e-19 68.8 0.1 8.4e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO23695.1 - 1e-17 64.6 0.3 3.2e-17 63.0 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO23695.1 - 1.2e-14 54.4 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO23695.1 - 3.7e-14 52.6 0.0 8.7e-14 51.4 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGO23695.1 - 1.2e-13 51.6 0.0 2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO23695.1 - 5.5e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGO23695.1 - 2.1e-07 30.7 0.0 4e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGO23695.1 - 2.3e-07 30.5 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EGO23695.1 - 4.3e-06 25.9 0.0 5.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EGO23695.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGO23695.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO23695.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 EGO23695.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.3 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_7 PF03492.15 EGO23695.1 - 0.017 14.3 0.0 1.6 7.9 0.0 2.7 3 0 0 3 3 3 0 SAM dependent carboxyl methyltransferase Fibrillarin PF01269.17 EGO23695.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 EGO23695.1 - 0.039 14.0 0.2 0.38 10.8 0.1 2.3 2 1 0 2 2 2 0 FtsJ-like methyltransferase DOT1 PF08123.13 EGO23695.1 - 0.042 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 EGO23695.1 - 0.063 12.9 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FIST_C PF10442.9 EGO23695.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 FIST C domain UPF0020 PF01170.18 EGO23695.1 - 0.11 12.2 0.3 1.3 8.6 0.3 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 GCD14 PF08704.10 EGO23695.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit LRR_4 PF12799.7 EGO23698.1 - 2.2e-24 85.1 33.0 0.001 19.4 0.1 8.6 7 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO23698.1 - 2.6e-22 78.3 33.7 4.8e-06 26.2 5.3 6.6 4 1 3 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 EGO23698.1 - 2.2e-14 53.3 8.6 0.002 17.7 1.0 5.5 2 1 2 5 5 5 5 Leucine-rich repeat Homeobox_KN PF05920.11 EGO23699.1 - 7e-19 67.5 0.1 7e-19 67.5 0.1 3.5 4 0 0 4 4 4 1 Homeobox KN domain Homeodomain PF00046.29 EGO23699.1 - 2.4e-05 24.1 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain DUF5447 PF17525.2 EGO23699.1 - 0.082 13.4 0.5 10 6.7 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5447) p450 PF00067.22 EGO23700.1 - 4.1e-65 220.3 0.0 6.9e-65 219.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_32 PF13679.6 EGO23701.1 - 1.6e-24 86.7 0.0 9e-24 84.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO23701.1 - 0.005 16.7 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO23701.1 - 0.013 16.1 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.14 EGO23701.1 - 0.055 13.0 0.1 11 5.5 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase TRM13 Methyltransf_25 PF13649.6 EGO23701.1 - 0.064 14.0 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HVSL PF09749.9 EGO23702.1 - 1.1e-39 136.3 0.1 2e-39 135.5 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EGO23702.1 - 1.5e-09 37.9 0.9 2.7e-09 37.1 0.9 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily cobW PF02492.19 EGO23703.1 - 2.4e-32 111.9 0.0 2.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGO23703.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EGO23703.1 - 0.015 14.3 0.1 0.43 9.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGO23703.1 - 0.024 15.2 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO23703.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 EGO23703.1 - 0.06 13.9 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 EGO23703.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 EGO23703.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EGO23703.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Aldo_ket_red PF00248.21 EGO23704.1 - 8e-68 228.8 0.3 9.1e-68 228.6 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_syn_2C PF08485.10 EGO23704.1 - 0.15 11.8 0.4 0.47 10.2 0.4 1.8 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Iwr1 PF08574.10 EGO23705.1 - 8.4e-15 55.5 6.8 8.4e-15 55.5 6.8 3.1 3 1 0 3 3 3 1 Transcription factor Iwr1 His_Phos_2 PF00328.22 EGO23706.1 - 0.0016 17.9 0.2 1.3 8.3 0.0 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) HCO3_cotransp PF00955.21 EGO23707.1 - 3.2e-73 247.3 3.6 2.9e-35 122.1 1.2 3.0 2 1 1 3 3 3 3 HCO3- transporter family Sulfate_transp PF00916.20 EGO23707.1 - 0.0031 16.3 4.4 0.007 15.2 0.6 2.3 2 0 0 2 2 2 2 Sulfate permease family Abhydrolase_6 PF12697.7 EGO23708.1 - 5.6e-13 50.0 0.6 5.6e-13 50.0 0.6 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO23708.1 - 6.8e-13 48.4 0.1 2e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO23708.1 - 6.5e-09 35.8 0.3 4e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGO23708.1 - 3.2e-08 33.7 0.1 6.4e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO23708.1 - 0.00011 22.1 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EGO23708.1 - 0.00012 21.8 0.2 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 EGO23708.1 - 0.00014 20.9 0.5 0.0019 17.2 0.5 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EGO23708.1 - 0.00065 19.2 0.1 0.55 9.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 EGO23708.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 EGO23708.1 - 0.0026 17.4 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.25 EGO23708.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EGO23708.1 - 0.0065 16.1 0.2 1.4 8.6 0.0 3.0 1 1 0 2 2 2 1 Putative esterase DUF818 PF05677.12 EGO23708.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Ser_hydrolase PF06821.13 EGO23708.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 EGO23708.1 - 0.026 14.1 0.0 0.078 12.5 0.0 1.7 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase PAF-AH_p_II PF03403.13 EGO23708.1 - 0.029 12.9 0.1 1.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 EGO23708.1 - 0.03 14.1 0.0 0.075 12.7 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein DUF1057 PF06342.12 EGO23708.1 - 0.034 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF3089 PF11288.8 EGO23708.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.7 EGO23708.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.28 EGO23708.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family PHY PF00360.20 EGO23709.1 - 4.1e-23 81.6 0.0 7.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EGO23709.1 - 4.1e-21 75.6 0.0 8.6e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO23709.1 - 2.3e-18 66.4 0.1 5.2e-17 62.0 0.1 2.5 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EGO23709.1 - 5e-15 56.3 0.1 4.3e-14 53.3 0.1 2.4 2 1 0 2 2 2 1 GAF domain HisKA PF00512.25 EGO23709.1 - 2.1e-11 43.7 1.4 7.5e-11 41.9 1.4 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGO23709.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 EGO23710.1 - 5.6e-47 159.7 0.0 7.4e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23710.1 - 7.6e-37 127.1 0.0 9.4e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO23710.1 - 4e-07 30.1 0.0 1.4e-06 28.3 0.0 1.8 3 0 0 3 3 3 1 KR domain DUF1776 PF08643.10 EGO23710.1 - 3.1e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGO23710.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_ligase_OB PF03120.16 EGO23710.1 - 0.099 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Aldo_ket_red PF00248.21 EGO23712.1 - 1.5e-17 63.8 0.0 1.7e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UNC119_bdg PF15435.6 EGO23712.1 - 0.17 11.4 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue DUF202 PF02656.15 EGO23713.1 - 6e-18 65.0 0.3 6e-18 65.0 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Blt1 PF12754.7 EGO23713.1 - 0.17 12.2 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain E1-E2_ATPase PF00122.20 EGO23713.1 - 0.18 11.4 1.8 0.26 10.8 1.8 1.2 1 0 0 1 1 1 0 E1-E2 ATPase MORN PF02493.20 EGO23715.1 - 0.074 13.0 0.6 0.68 9.9 0.1 2.6 2 0 0 2 2 2 0 MORN repeat MMR_HSR1 PF01926.23 EGO23716.1 - 0.00021 21.3 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO23716.1 - 0.00046 19.6 0.2 0.00088 18.7 0.2 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGO23716.1 - 0.0073 16.2 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGO23716.1 - 0.0089 16.5 0.8 0.017 15.6 0.8 1.6 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 EGO23716.1 - 0.022 14.8 0.2 0.045 13.8 0.2 1.6 1 1 0 1 1 1 0 Dynamin family F-box-like PF12937.7 EGO23717.1 - 0.013 15.4 0.2 0.038 13.9 0.2 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 EGO23718.1 - 3.7e-47 161.0 14.2 5.1e-47 160.5 14.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO23718.1 - 1.7e-07 30.5 8.0 1.7e-07 30.5 8.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EGO23718.1 - 2.6e-05 22.7 1.0 0.0011 17.4 0.2 2.4 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2883 PF11097.8 EGO23718.1 - 0.12 12.5 0.4 0.26 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) WBP-1 PF11669.8 EGO23718.1 - 0.13 12.9 0.0 0.5 11.0 0.0 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 DNA_pol_A_exo1 PF01612.20 EGO23719.1 - 7.7e-46 156.0 0.1 1.2e-45 155.4 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EGO23719.1 - 1.3e-21 77.1 2.7 1.3e-21 77.1 2.7 2.9 4 0 0 4 4 4 1 PMC2NT (NUC016) domain HRDC PF00570.23 EGO23719.1 - 4.3e-10 39.4 0.0 1.2e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 HRDC domain AATF-Che1 PF13339.6 EGO23719.1 - 2.1 9.0 4.8 1 10.1 0.2 2.8 4 0 0 4 4 4 0 Apoptosis antagonizing transcription factor FIST PF08495.10 EGO23720.1 - 1e-05 25.6 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 FIST N domain ETF PF01012.21 EGO23721.1 - 2.8e-43 147.9 1.5 3.7e-43 147.5 1.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CoA_transf_3 PF02515.17 EGO23722.1 - 2.9e-47 161.6 0.0 6.6e-40 137.4 0.0 2.6 2 1 0 2 2 2 2 CoA-transferase family III Peptidase_M16 PF00675.20 EGO23723.1 - 3.9e-52 176.2 0.8 7e-52 175.4 0.8 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO23723.1 - 3.7e-28 98.8 0.0 3.8e-25 89.0 0.0 3.8 3 1 0 3 3 3 1 Peptidase M16 inactive domain MTD PF01993.18 EGO23723.1 - 0.037 13.4 0.0 1.6 8.0 0.0 2.3 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase ChiW_Ig_like PF18683.1 EGO23723.1 - 0.078 13.2 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain Pkinase PF00069.25 EGO23724.1 - 1.5e-69 234.3 0.0 1.7e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23724.1 - 1.5e-41 142.4 0.0 1.8e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO23724.1 - 1.4e-06 27.8 0.0 3e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGO23724.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO23724.1 - 0.011 15.6 0.2 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGO23724.1 - 0.033 13.8 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EGO23724.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pectinesterase PF01095.19 EGO23725.1 - 2.9e-36 124.7 2.9 9.8e-36 123.0 2.9 1.7 1 1 0 1 1 1 1 Pectinesterase Nup54_C PF18437.1 EGO23727.1 - 0.0039 17.0 1.2 0.022 14.6 0.2 2.5 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain DUF4194 PF13835.6 EGO23727.1 - 0.0063 16.3 0.2 0.83 9.4 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4194) Cas_DxTHG PF09455.10 EGO23727.1 - 0.008 15.8 0.2 0.0099 15.5 0.2 1.1 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family PI3K_1B_p101 PF10486.9 EGO23727.1 - 0.0099 13.7 4.7 0.014 13.2 4.7 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HMGL-like PF00682.19 EGO23727.1 - 0.033 13.7 3.4 0.91 9.0 0.2 2.2 1 1 1 2 2 2 0 HMGL-like DegQ PF08181.11 EGO23727.1 - 0.054 13.6 0.1 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 DegQ (SacQ) family T3SS_needle_E PF08988.10 EGO23727.1 - 0.068 13.3 1.8 1.2 9.3 1.0 2.7 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle HSCB_C PF07743.13 EGO23727.1 - 0.074 13.6 4.6 5.6 7.5 0.0 3.4 2 2 2 4 4 4 0 HSCB C-terminal oligomerisation domain TMF_TATA_bd PF12325.8 EGO23727.1 - 0.089 13.0 5.4 0.33 11.2 0.6 3.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2680 PF10925.8 EGO23727.1 - 0.12 12.4 0.1 32 4.6 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2680) GDWWSH PF15667.5 EGO23727.1 - 0.14 11.5 4.2 0.23 10.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH DUF4665 PF15679.5 EGO23727.1 - 0.15 12.7 0.3 23 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) WXG100 PF06013.12 EGO23727.1 - 0.18 12.0 5.7 12 6.2 0.3 3.6 3 2 0 3 3 3 0 Proteins of 100 residues with WXG PE PF00934.20 EGO23727.1 - 0.21 11.9 8.3 0.26 11.6 4.7 2.5 1 1 1 2 2 2 0 PE family Vps53_N PF04100.12 EGO23727.1 - 0.5 9.3 8.1 14 4.5 0.5 3.0 1 1 2 3 3 3 0 Vps53-like, N-terminal Anti-adapt_IraP PF10796.9 EGO23727.1 - 0.53 10.9 10.8 12 6.5 0.1 3.7 2 2 2 4 4 4 0 Sigma-S stabilisation anti-adaptor protein SKA1 PF07160.12 EGO23727.1 - 0.54 10.1 3.4 7.2 6.4 0.1 2.8 1 1 3 4 4 4 0 Spindle and kinetochore-associated protein 1 V-SNARE PF05008.15 EGO23727.1 - 0.71 10.3 5.0 5.2 7.5 0.1 3.5 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.12 EGO23727.1 - 2.7 8.5 15.1 22 5.6 4.2 4.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CoatB PF10389.9 EGO23727.1 - 5.6 6.9 9.6 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Bacteriophage coat protein B Swi5 PF07061.11 EGO23727.1 - 5.7 7.1 8.0 20 5.3 0.5 3.0 3 1 0 3 3 3 0 Swi5 Pectinesterase PF01095.19 EGO23728.1 - 2.5e-36 124.9 2.3 7.3e-32 110.3 2.4 2.1 1 1 1 2 2 2 2 Pectinesterase Syntaxin_2 PF14523.6 EGO23729.1 - 1.2e-22 80.2 9.4 8.7e-21 74.2 7.1 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 EGO23729.1 - 4e-14 52.3 1.8 1.3e-11 44.2 0.3 2.4 2 0 0 2 2 2 2 SNARE domain Syntaxin PF00804.25 EGO23729.1 - 3.1e-08 33.5 11.1 3.9e-07 29.9 11.1 2.1 1 1 0 1 1 1 1 Syntaxin Halogen_Hydrol PF10112.9 EGO23729.1 - 0.082 12.9 1.7 0.24 11.4 0.4 2.3 1 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DAPDH_C PF16654.5 EGO23729.1 - 0.087 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Synaptobrevin PF00957.21 EGO23729.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Synaptobrevin His_kinase PF06580.13 EGO23729.1 - 0.4 11.0 3.4 1.5 9.2 0.6 2.9 2 2 1 3 3 3 0 Histidine kinase Orf78 PF06024.12 EGO23729.1 - 0.46 10.8 3.3 2.5 8.5 0.2 2.7 2 1 1 3 3 3 0 Orf78 (ac78) Tom5 PF10642.9 EGO23729.1 - 1 9.4 3.4 0.9 9.6 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase FlaC_arch PF05377.11 EGO23729.1 - 1.3 9.4 4.5 60 4.1 0.1 4.0 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 EGO23733.1 - 5.7e-63 212.7 0.0 1e-62 211.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23733.1 - 3.8e-41 141.1 0.0 4e-40 137.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO23733.1 - 0.00054 18.9 0.0 0.00091 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO23733.1 - 0.027 13.8 0.0 0.12 11.7 0.0 1.9 1 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 EGO23733.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Ric8 PF10165.9 EGO23733.1 - 0.2 10.7 2.1 14 4.6 0.2 2.8 1 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DUF4704 PF15787.5 EGO23733.1 - 0.54 9.5 7.0 4.2 6.5 0.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4704) RICTOR_N PF14664.6 EGO23733.1 - 3.5 6.5 16.1 0.25 10.3 0.2 3.7 2 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Ribosomal_L5_C PF00673.21 EGO23734.1 - 1.9e-27 95.3 0.0 3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGO23734.1 - 0.014 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L5 Peptidase_M64 PF09471.10 EGO23735.1 - 2.3e-25 89.7 0.0 2.1e-24 86.5 0.0 2.2 1 1 0 1 1 1 1 IgA Peptidase M64 Ribosomal_L1 PF00687.21 EGO23736.1 - 5.3e-56 189.6 0.4 5.3e-56 189.6 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family CDC45 PF02724.14 EGO23736.1 - 0.87 7.8 6.2 1.3 7.3 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Hydrolase_4 PF12146.8 EGO23737.1 - 1.9e-08 33.8 0.1 7.9e-07 28.6 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGO23737.1 - 2.9e-06 26.9 0.4 6.2e-06 25.8 0.4 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGO23737.1 - 1.1e-05 26.2 0.3 3e-05 24.7 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO23737.1 - 8.3e-05 22.4 0.3 0.00078 19.2 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 EGO23737.1 - 0.00087 18.5 0.3 0.0016 17.6 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) DUF915 PF06028.11 EGO23737.1 - 0.012 14.9 0.0 0.031 13.6 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) OST3_OST6 PF04756.13 EGO23739.1 - 0.18 11.1 0.0 0.22 10.8 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Dynamin_N PF00350.23 EGO23740.1 - 6.2e-19 68.7 2.6 6.6e-19 68.6 0.1 2.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EGO23740.1 - 1.3e-12 47.8 0.0 1.2e-11 44.7 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO23740.1 - 1.1e-06 28.3 0.0 0.00052 19.6 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO23740.1 - 0.0033 17.3 1.3 0.41 10.5 0.3 2.8 2 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EGO23740.1 - 0.0044 16.6 0.5 0.1 12.2 0.5 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EGO23740.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EGO23740.1 - 0.024 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EGO23740.1 - 0.091 13.0 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 EGO23740.1 - 0.12 11.4 0.4 0.32 10.0 0.0 2.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Aldo_ket_red PF00248.21 EGO23741.1 - 3e-69 233.5 0.3 3.4e-69 233.3 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EGO23744.1 - 7.5e-71 238.7 0.3 8.6e-71 238.5 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 EGO23745.1 - 4.5e-34 118.0 0.0 1e-20 74.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO23745.1 - 1.3e-29 103.0 0.0 9e-29 100.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO23745.1 - 4.6e-06 26.7 0.1 3.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 EGO23745.1 - 0.0065 15.9 0.0 0.058 12.8 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) AidB_N PF18158.1 EGO23747.1 - 1.1e-25 90.4 0.0 2.4e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGO23747.1 - 8.8e-19 68.2 4.8 1.5e-18 67.4 4.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO23747.1 - 9.1e-12 45.0 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO23747.1 - 1.4e-07 31.9 0.7 2.7e-07 30.9 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO23747.1 - 0.018 15.7 0.0 0.093 13.4 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Aldo_ket_red PF00248.21 EGO23748.1 - 2.7e-71 240.1 0.2 3.1e-71 240.0 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC_3 PF13917.6 EGO23749.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO23749.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO23749.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO23749.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Aldo_ket_red PF00248.21 EGO23753.1 - 3.5e-71 239.8 0.2 4.1e-71 239.6 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dimer_Tnp_hAT PF05699.14 EGO23754.1 - 1.2e-20 73.1 0.4 1.7e-20 72.6 0.4 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NFRKB_winged PF14465.6 EGO23754.1 - 0.014 15.6 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 NFRKB Winged Helix-like Peptidase_A17 PF05380.13 EGO23755.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase ENTH PF01417.20 EGO23758.1 - 4.1e-44 149.6 0.0 6.1e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGO23758.1 - 0.0094 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 ANTH domain Glyco_hydro_20 PF00728.22 EGO23759.1 - 2.9e-95 319.7 0.1 3.4e-95 319.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGO23759.1 - 8.2e-10 39.5 0.1 3.1e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGO23759.1 - 0.00037 21.3 0.0 0.001 19.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RNA_pol_Rpb4 PF03874.16 EGO23760.1 - 7.2e-21 74.8 0.0 9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 NOT2_3_5 PF04153.18 EGO23761.1 - 7.3e-31 107.0 1.1 7.3e-31 107.0 1.1 2.5 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Prenyltrans PF00432.21 EGO23762.1 - 5e-34 115.7 8.9 2.4e-09 36.8 1.7 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGO23762.1 - 0.0025 17.0 0.0 0.31 10.1 0.0 2.4 2 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGO23762.1 - 0.014 14.6 0.0 0.058 12.5 0.0 1.9 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 EGO23762.1 - 0.17 10.9 0.0 6 5.8 0.0 2.4 2 0 0 2 2 2 0 A-macroglobulin TED domain MIF4G PF02854.19 EGO23763.1 - 0.014 15.0 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 MIF4G domain HET PF06985.11 EGO23764.1 - 0.091 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Palm_thioest PF02089.15 EGO23765.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGO23765.1 - 0.0021 17.8 0.3 0.01 15.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO23765.1 - 0.0022 18.7 0.1 0.0037 17.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO23765.1 - 0.0083 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGO23765.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ELFV_dehydrog PF00208.21 EGO23766.1 - 5.5e-55 186.7 0.0 7.5e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EGO23766.1 - 8.6e-19 66.7 0.1 5.6e-13 47.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase adh_short PF00106.25 EGO23767.1 - 9.4e-39 132.9 0.4 2.4e-22 79.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23767.1 - 1.7e-28 99.8 0.4 6.9e-19 68.3 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO23767.1 - 9.2e-05 22.4 0.1 0.00088 19.2 0.1 2.1 2 0 0 2 2 2 1 KR domain SAM_2 PF07647.17 EGO23768.1 - 4.4e-08 33.1 0.0 1.6e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGO23768.1 - 0.00027 21.3 0.1 0.0008 19.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EGO23768.1 - 0.074 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Lamprin PF06403.11 EGO23768.1 - 1.7 8.6 6.4 0.24 11.3 1.9 1.8 1 1 1 2 2 2 0 Lamprin Spt20 PF12090.8 EGO23768.1 - 2.4 7.7 9.8 4.5 6.8 9.8 1.4 1 0 0 1 1 1 0 Spt20 family DIOX_N PF14226.6 EGO23769.1 - 7.3e-33 113.8 0.0 1.1e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO23769.1 - 1.2e-22 80.3 0.0 2.4e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Disaggr_repeat PF06848.11 EGO23769.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Disaggregatase related repeat ADH_N_2 PF16884.5 EGO23770.1 - 6.3e-07 29.3 0.0 6.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGO23771.1 - 1.8e-22 79.7 0.0 3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO23771.1 - 2.8e-16 59.4 0.0 6.1e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGO23771.1 - 1e-07 33.1 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EGO23771.1 - 0.03 14.1 0.1 0.062 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) TrkA_N PF02254.18 EGO23771.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Ank_4 PF13637.6 EGO23772.1 - 1.5e-29 102.0 0.3 2.2e-05 24.9 0.0 5.3 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO23772.1 - 2.6e-28 98.4 0.0 1.7e-12 47.7 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO23772.1 - 3.8e-22 78.1 0.3 1.1e-10 41.5 0.0 4.5 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGO23772.1 - 8.4e-20 70.3 0.2 0.00044 20.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EGO23772.1 - 5.2e-18 63.3 0.1 0.0016 18.8 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Retrotrans_gag PF03732.17 EGO23773.1 - 0.00017 21.8 0.0 0.0005 20.3 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein PhoU PF01895.19 EGO23774.1 - 0.14 12.6 0.1 0.19 12.2 0.1 1.2 1 0 0 1 1 1 0 PhoU domain Retrotrans_gag PF03732.17 EGO23776.1 - 0.00029 21.0 5.4 0.00029 21.0 5.4 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 EGO23776.1 - 0.0036 17.4 0.3 0.0089 16.1 0.3 1.8 1 1 0 1 1 1 1 Sperm tail C-terminal domain NRN1 PF15056.6 EGO23776.1 - 0.034 14.2 1.3 0.068 13.3 1.3 1.5 1 0 0 1 1 1 0 Neuritin protein family GFRP PF06399.13 EGO23778.1 - 0.079 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) ADH_zinc_N PF00107.26 EGO23779.1 - 1.1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO23779.1 - 2.1e-09 37.3 0.0 9e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGO23779.1 - 1e-07 33.1 0.0 2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 EGO23779.1 - 0.00034 20.9 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Thi4 PF01946.17 EGO23780.1 - 1.4e-103 345.2 0.1 1.6e-103 345.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGO23780.1 - 5.1e-10 39.5 1.8 2.8e-09 37.0 0.5 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGO23780.1 - 1.5e-07 30.8 0.9 2.5e-06 26.8 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGO23780.1 - 2.5e-07 30.2 0.0 3.5e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO23780.1 - 3.8e-07 30.2 0.1 1.3e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO23780.1 - 4.4e-06 26.0 1.7 8.6e-05 21.8 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EGO23780.1 - 1.9e-05 24.7 2.1 0.00023 21.2 0.1 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGO23780.1 - 0.00015 20.6 0.5 0.00032 19.5 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EGO23780.1 - 0.00019 20.9 0.3 0.00028 20.4 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGO23780.1 - 0.0061 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGO23780.1 - 0.0082 15.4 0.1 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO23780.1 - 0.015 14.4 0.2 0.068 12.2 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 EGO23780.1 - 0.048 12.8 0.0 0.35 9.9 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EGO23780.1 - 0.093 11.6 0.3 0.15 10.9 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase RPN5_C PF18098.1 EGO23784.1 - 0.025 14.7 1.1 0.11 12.6 0.1 2.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Plavaka PF18759.1 EGO23785.1 - 5.5e-23 81.7 0.0 1.1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase DUF4763 PF15960.5 EGO23787.1 - 0.00055 19.3 9.3 0.00095 18.5 0.4 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4763) CcmH PF03918.14 EGO23787.1 - 0.029 13.7 0.7 0.068 12.5 0.7 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein KxDL PF10241.9 EGO23787.1 - 0.038 14.3 2.9 0.038 14.3 2.9 2.7 2 1 2 4 4 3 0 Uncharacterized conserved protein Mod_r PF07200.13 EGO23787.1 - 0.17 12.0 10.9 0.23 11.6 6.4 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Acetyltransf_11 PF13720.6 EGO23787.1 - 0.5 10.9 5.5 4.3 7.9 1.1 3.0 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Ntox28 PF15605.6 EGO23787.1 - 0.62 10.3 8.1 0.66 10.2 0.7 2.7 2 0 0 2 2 2 0 Bacterial toxin 28 APG6_N PF17675.1 EGO23787.1 - 0.77 10.3 19.0 0.66 10.5 3.3 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Med4 PF10018.9 EGO23787.1 - 0.97 9.1 10.3 0.64 9.7 6.3 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TolA_bind_tri PF16331.5 EGO23787.1 - 1.2 9.3 10.9 0.17 12.0 2.3 2.6 1 1 1 2 2 2 0 TolA binding protein trimerisation V_ATPase_I PF01496.19 EGO23787.1 - 1.2 6.9 5.1 1.5 6.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.9 EGO23787.1 - 1.8 8.5 15.7 2 8.3 9.0 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.12 EGO23787.1 - 1.8 8.6 17.5 0.58 10.2 9.4 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EGO23787.1 - 3 6.8 9.4 4.5 6.3 9.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 EGO23787.1 - 6.2 6.9 15.7 5 7.2 6.4 3.0 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EGO23787.1 - 8.7 6.9 19.8 0.65 10.5 9.5 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 EGO23787.1 - 8.8 6.5 20.5 26 5.0 19.3 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Tox-HDC PF15656.6 EGO23788.1 - 0.048 13.8 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF3242 PF11586.8 EGO23789.1 - 0.05 13.3 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) CM_2 PF01817.21 EGO23790.1 - 1e-05 25.8 0.3 0.082 13.3 0.0 2.9 3 0 0 3 3 3 2 Chorismate mutase type II RPAP1_N PF08621.10 EGO23790.1 - 0.16 11.8 1.3 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal Septin PF00735.18 EGO23791.1 - 2.3e-47 161.6 0.3 9e-18 64.5 0.1 3.3 3 1 0 3 3 3 3 Septin GTP_EFTU PF00009.27 EGO23791.1 - 6.4e-06 25.8 0.1 6.3e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO23791.1 - 2.9e-05 24.1 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EGO23791.1 - 0.00017 21.8 1.4 0.00054 20.2 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO23791.1 - 0.0026 18.2 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO23791.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 EGO23791.1 - 0.1 12.6 0.3 14 5.7 0.0 2.3 1 1 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 EGO23791.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.10 EGO23791.1 - 0.17 11.3 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EGO23792.1 - 9e-31 107.2 0.0 6e-10 38.9 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 EGO23792.1 - 4e-10 39.7 9.9 4e-10 39.7 9.9 3.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EGO23793.1 - 6.6e-10 38.9 10.6 1.2e-09 38.2 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CATSPERB PF15149.6 EGO23793.1 - 5.4 5.4 4.6 4.8 5.6 0.3 2.0 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit beta protein family ILVD_EDD PF00920.21 EGO23795.1 - 1.2e-207 690.7 0.0 1.4e-207 690.4 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family NqrM PF04400.13 EGO23795.1 - 0.94 9.3 3.5 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 (Na+)-NQR maturation NqrM Orf78 PF06024.12 EGO23796.1 - 0.0032 17.7 0.1 0.008 16.5 0.0 1.6 2 0 0 2 2 2 1 Orf78 (ac78) DUF4504 PF14953.6 EGO23800.1 - 1.4e-05 24.6 0.1 1.5e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Pro_isomerase PF00160.21 EGO23801.1 - 8.6e-50 169.1 0.0 1.6e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGO23801.1 - 2.5e-07 31.3 0.5 0.0022 18.8 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-AN1 PF01428.16 EGO23802.1 - 5.2e-13 48.9 18.7 1.3e-11 44.4 8.2 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger DUF5388 PF17363.2 EGO23802.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Transp_Tc5_C PF04236.15 EGO23802.1 - 0.44 10.9 7.4 0.26 11.7 2.5 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain His_Phos_1 PF00300.22 EGO23803.1 - 4.5e-34 117.8 0.1 7.8e-34 117.1 0.1 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Eaf7 PF07904.13 EGO23804.1 - 3.3e-15 56.4 0.0 5.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Arrestin_C PF02752.22 EGO23805.1 - 0.00069 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain HECT PF00632.25 EGO23806.1 - 1.6e-93 313.6 0.0 2.2e-93 313.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EGO23806.1 - 3.1e-37 126.3 18.3 3.3e-13 49.5 0.6 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EGO23806.1 - 2.7e-17 62.9 0.0 5.7e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain RasGEF_N PF00618.20 EGO23807.1 - 1e-19 70.7 0.2 6.8e-18 64.8 0.0 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif RasGEF PF00617.19 EGO23807.1 - 4.3e-17 62.9 0.0 9.5e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGAP PF00616.19 EGO23807.1 - 0.15 11.8 0.5 10 5.7 0.0 2.3 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Ribosomal_L22 PF00237.19 EGO23808.1 - 3.2e-34 117.2 0.1 4.8e-34 116.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RE_Eco29kI PF09517.10 EGO23808.1 - 0.0064 16.1 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 Eco29kI restriction endonuclease RICTOR_N PF14664.6 EGO23809.1 - 7e-123 410.3 0.0 1.1e-122 409.6 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EGO23809.1 - 1.8e-38 130.4 0.8 1.5e-35 121.1 0.0 4.4 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EGO23809.1 - 8.7e-38 129.0 0.5 2.7e-35 121.0 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EGO23809.1 - 1.1e-31 108.8 0.0 1.1e-28 99.3 0.0 4.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EGO23809.1 - 2.2e-09 37.3 1.3 5.9e-09 35.9 1.3 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 EGO23809.1 - 1.5e-05 24.9 1.0 10 6.7 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EGO23809.1 - 0.12 12.9 0.1 20 5.8 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat Uds1 PF15456.6 EGO23809.1 - 0.27 11.4 5.7 0.18 12.0 0.4 2.8 3 0 0 3 3 3 0 Up-regulated During Septation CCDC24 PF15669.5 EGO23809.1 - 4.1 7.2 6.4 14 5.5 0.2 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family FMO-like PF00743.19 EGO23810.1 - 1.3e-15 56.8 0.1 2.9e-15 55.7 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO23810.1 - 5.6e-08 32.4 0.3 1.3e-06 27.9 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO23810.1 - 7.8e-07 29.2 0.0 5.5e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGO23810.1 - 1.7e-06 27.4 0.1 5.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGO23810.1 - 1.2e-05 24.7 0.0 0.0011 18.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO23810.1 - 0.19 11.3 0.2 0.36 10.4 0.2 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase ETC_C1_NDUFA4 PF04800.12 EGO23811.1 - 1.3e-36 124.8 0.7 1.8e-36 124.2 0.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region RSN1_7TM PF02714.15 EGO23812.1 - 1.9e-40 138.9 19.6 3.5e-40 138.0 19.6 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGO23812.1 - 4.6e-23 82.4 0.0 1.9e-16 60.8 0.0 3.0 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGO23812.1 - 3.9e-15 56.0 1.5 8.8e-15 54.8 0.2 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport GH131_N PF18271.1 EGO23813.1 - 3.6e-57 194.0 0.9 4.8e-57 193.6 0.9 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 EGO23813.1 - 2.5e-10 40.1 10.5 6.9e-10 38.7 10.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Polysacc_lyase PF14099.6 EGO23813.1 - 0.011 15.6 1.4 0.015 15.1 0.5 1.6 1 1 0 1 1 1 0 Polysaccharide lyase Sod_Cu PF00080.20 EGO23814.1 - 4.1e-46 156.7 1.4 5e-46 156.4 1.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EGO23814.1 - 0.0063 17.5 0.4 0.011 16.6 0.3 1.6 1 1 0 1 1 1 1 CHRD domain Motile_Sperm PF00635.26 EGO23815.1 - 2.3e-26 91.8 0.2 5.1e-26 90.6 0.2 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 EGO23815.1 - 0.00017 21.7 0.1 0.00036 20.7 0.1 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1192 PF06698.11 EGO23815.1 - 0.044 13.8 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4133 PF13571.6 EGO23817.1 - 6.2 7.2 7.3 1.8 8.9 4.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) ABM PF03992.16 EGO23818.1 - 0.02 15.0 0.0 0.15 12.2 0.0 2.0 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Mito_carr PF00153.27 EGO23819.1 - 1.7e-41 140.1 2.4 2.7e-16 59.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MutS_V PF00488.21 EGO23820.1 - 8.4e-41 140.1 0.1 2.9e-39 135.1 0.1 2.2 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO23820.1 - 1.1e-30 107.3 0.0 2.7e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGO23820.1 - 0.0021 18.4 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 EGO23820.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.25 EGO23821.1 - 1.3e-20 74.2 0.7 1.8e-20 73.7 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.14 EGO23822.1 - 6e-36 122.0 6.4 2.4e-20 72.1 2.0 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF5090 PF17009.5 EGO23822.1 - 0.022 14.8 1.8 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF1640 PF07798.11 EGO23822.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) F-box-like PF12937.7 EGO23823.1 - 0.00012 21.9 0.3 0.00012 21.9 0.3 3.1 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 EGO23823.1 - 0.075 13.5 6.9 20 5.8 0.1 4.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO23823.1 - 0.11 13.1 3.0 41 5.3 0.0 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat zf-TFIIB PF13453.6 EGO23826.1 - 0.13 11.6 2.3 0.17 11.2 0.2 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger KDZ PF18758.1 EGO23827.1 - 3.2e-12 46.6 0.1 8e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase eRF1_2 PF03464.15 EGO23829.1 - 0.088 13.1 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 eRF1 domain 2 fn3_4 PF16794.5 EGO23833.1 - 0.15 12.0 0.1 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Fibronectin-III type domain PPP4R2 PF09184.11 EGO23835.1 - 0.17 11.4 8.4 0.19 11.3 8.4 1.0 1 0 0 1 1 1 0 PPP4R2 MRP_L53 PF10780.9 EGO23836.1 - 0.1 12.8 0.4 0.14 12.4 0.4 1.2 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Unstab_antitox PF09720.10 EGO23837.1 - 0.068 13.2 0.9 0.086 12.9 0.7 1.3 1 1 0 1 1 1 0 Putative addiction module component DUF2663 PF10864.8 EGO23838.1 - 0.11 12.9 1.3 0.16 12.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Pkinase_C PF00433.24 EGO23839.1 - 5.1e-10 39.9 0.2 8.4e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase PF00069.25 EGO23839.1 - 0.048 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DDE_Tnp_4 PF13359.6 EGO23840.1 - 4e-06 26.6 0.0 6.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LacI PF00356.21 EGO23840.1 - 0.018 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF4541 PF15074.6 EGO23841.1 - 0.15 12.7 0.7 0.3 11.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) DUF809 PF05663.11 EGO23844.1 - 1.8 8.7 8.5 3.3 7.9 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Peptidase_M60_C PF18630.1 EGO23847.1 - 0.036 14.2 0.0 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain Retrotrans_gag PF03732.17 EGO23847.1 - 0.049 13.9 0.6 0.098 12.9 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein DUF1823 PF08853.11 EGO23847.1 - 0.097 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) DNA_pol3_beta_3 PF02768.15 EGO23847.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain DUF3527 PF12043.8 EGO23848.1 - 0.0011 18.6 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) rve PF00665.26 EGO23849.1 - 5.6e-05 23.3 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO23849.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Pkinase PF00069.25 EGO23853.1 - 1.7e-70 237.4 0.0 2.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO23853.1 - 1e-31 110.2 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGO23853.1 - 9.3e-11 42.3 1.5 9.3e-11 42.3 1.5 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGO23853.1 - 4.1e-07 29.3 0.2 6.2e-07 28.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO23853.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGO23853.1 - 0.0055 16.4 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGO23853.1 - 0.034 13.5 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO23853.1 - 0.043 13.7 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Inhibitor_Mig-6 PF11555.8 EGO23853.1 - 0.046 13.8 0.3 0.5 10.5 0.0 2.5 2 1 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Choline_kinase PF01633.20 EGO23853.1 - 0.15 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Proteasome PF00227.26 EGO23854.1 - 3.5e-48 163.6 0.1 4.4e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit ABC_membrane PF00664.23 EGO23855.1 - 9.2e-105 350.2 26.3 2e-52 178.5 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO23855.1 - 7.3e-69 230.6 0.1 1.2e-33 116.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGO23855.1 - 2.3e-14 53.4 1.1 0.0003 20.3 0.1 4.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGO23855.1 - 1.2e-08 34.2 0.2 0.00086 18.2 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EGO23855.1 - 4e-08 33.4 0.6 0.0011 18.9 0.0 3.7 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO23855.1 - 2.5e-07 30.3 0.9 0.032 14.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGO23855.1 - 6.9e-07 29.3 0.1 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGO23855.1 - 1.9e-06 28.2 1.1 0.024 14.9 0.0 3.9 4 1 0 4 4 2 2 AAA domain AAA_16 PF13191.6 EGO23855.1 - 1.4e-05 25.6 6.6 0.0062 16.9 0.1 3.4 2 1 1 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.12 EGO23855.1 - 3.3e-05 23.3 0.0 0.084 12.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EGO23855.1 - 4.1e-05 23.5 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EGO23855.1 - 0.00014 21.1 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 EGO23855.1 - 0.00016 21.4 0.3 1.1 9.0 0.2 3.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGO23855.1 - 0.0003 20.4 1.8 0.34 10.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EGO23855.1 - 0.00066 20.2 0.0 0.6 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGO23855.1 - 0.0012 19.4 0.4 3.5 8.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGO23855.1 - 0.0027 17.9 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGO23855.1 - 0.0031 17.7 2.7 3.9 7.8 0.3 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EGO23855.1 - 0.0033 17.2 0.0 1.1 8.9 0.0 2.7 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 EGO23855.1 - 0.004 17.1 0.0 5.5 7.0 0.0 3.1 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EGO23855.1 - 0.008 16.3 0.8 5.4 7.0 0.3 3.3 3 0 0 3 3 2 1 Helicase HerA, central domain APS_kinase PF01583.20 EGO23855.1 - 0.0093 15.9 0.0 2.8 7.8 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_28 PF13521.6 EGO23855.1 - 0.012 15.8 0.1 4.5 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 EGO23855.1 - 0.013 15.6 0.2 9.2 6.4 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGO23855.1 - 0.018 14.3 0.0 0.95 8.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 EGO23855.1 - 0.018 14.6 0.0 9.9 5.6 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGO23855.1 - 0.021 14.2 0.3 4.3 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 EGO23855.1 - 0.041 14.3 0.0 20 5.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO23855.1 - 0.061 13.0 0.2 15 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGO23855.1 - 0.07 12.3 0.0 7.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Flavodoxin_3 PF12641.7 EGO23855.1 - 0.099 12.3 0.2 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain RNA_helicase PF00910.22 EGO23855.1 - 0.16 12.3 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 EGO23855.1 - 0.8 9.7 3.1 24 4.9 0.2 3.4 3 0 0 3 3 3 0 Dynamin family AAA PF00004.29 EGO23858.1 - 2.3e-40 138.1 0.0 4.3e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO23858.1 - 4.9e-20 71.2 0.2 9.6e-20 70.3 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGO23858.1 - 6.7e-12 45.0 0.1 1.5e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO23858.1 - 5.5e-05 23.6 0.4 0.012 15.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO23858.1 - 0.00051 20.3 0.7 0.12 12.7 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO23858.1 - 0.00069 19.6 0.2 0.0058 16.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO23858.1 - 0.0011 18.8 0.0 0.0024 17.6 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGO23858.1 - 0.0011 19.1 0.0 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGO23858.1 - 0.0068 16.6 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EGO23858.1 - 0.0075 15.7 0.1 0.055 12.9 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EGO23858.1 - 0.016 14.6 0.1 0.044 13.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EGO23858.1 - 0.021 14.6 0.2 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGO23858.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGO23858.1 - 0.085 12.6 0.2 0.25 11.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGO23858.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF1192 PF06698.11 EGO23858.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) XhlA PF10779.9 EGO23858.1 - 0.8 10.0 6.1 13 6.1 4.5 2.5 2 0 0 2 2 2 0 Haemolysin XhlA NuA4 PF09340.10 EGO23859.1 - 3.7e-24 84.4 1.0 6.8e-24 83.6 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Rrp40_N PF18311.1 EGO23860.1 - 1.6e-15 56.7 0.3 3.1e-15 55.8 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EGO23860.1 - 1.7e-11 44.3 0.0 3.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 KH domain Mod_r PF07200.13 EGO23861.1 - 2.9e-45 153.9 9.4 3.3e-45 153.8 9.4 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HMMR_N PF15905.5 EGO23861.1 - 0.034 13.6 4.0 0.023 14.2 2.7 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HMG_box PF00505.19 EGO23861.1 - 0.29 11.6 0.4 0.29 11.6 0.4 2.3 3 0 0 3 3 3 0 HMG (high mobility group) box GAS PF13851.6 EGO23861.1 - 0.43 9.9 6.5 0.66 9.3 4.8 2.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding p450 PF00067.22 EGO23862.1 - 3e-74 250.4 0.0 3.5e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec7 PF01369.20 EGO23863.1 - 1.3e-29 103.2 0.0 2e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGO23863.1 - 2.1e-15 57.1 0.0 3.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGO23863.1 - 6e-10 39.6 0.0 1.3e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Methyltransf_11 PF08241.12 EGO23864.1 - 3.5e-09 37.2 0.0 4.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO23864.1 - 8.5e-09 36.0 0.0 1e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO23864.1 - 1.8e-05 24.2 0.0 1.9e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO23864.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23864.1 - 0.014 15.1 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGO23864.1 - 0.071 13.9 0.0 0.087 13.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EGO23864.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-C3H1 PF10650.9 EGO23867.1 - 0.00098 18.8 0.6 0.0019 17.9 0.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain adh_short PF00106.25 EGO23870.1 - 1.2e-34 119.4 1.2 2.8e-29 102.0 0.1 2.6 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO23870.1 - 2e-19 70.1 0.0 2e-18 66.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO23870.1 - 3e-10 40.3 0.0 5.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO23870.1 - 0.00027 20.5 0.2 0.00045 19.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGO23870.1 - 0.0034 17.6 0.2 0.0057 16.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGO23870.1 - 0.0085 16.2 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGO23870.1 - 0.079 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EGO23870.1 - 0.093 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein VWA PF00092.28 EGO23871.1 - 2.3e-09 37.8 0.0 4.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGO23871.1 - 5.1e-06 27.1 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain EF_assoc_2 PF08356.12 EGO23872.1 - 4.8e-36 122.6 0.0 9.6e-36 121.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EGO23872.1 - 4.1e-32 111.0 0.0 3.7e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 EGO23872.1 - 1.1e-29 101.8 0.4 2.9e-29 100.5 0.4 1.8 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 EGO23872.1 - 4.3e-18 65.7 0.0 3.1e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO23872.1 - 1.9e-10 40.5 0.0 0.00016 21.1 0.0 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family EF-hand_7 PF13499.6 EGO23872.1 - 2.2e-09 37.7 0.3 0.0002 21.7 0.1 3.1 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO23872.1 - 2.7e-09 36.2 0.4 0.00016 21.3 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGO23872.1 - 6.2e-09 34.8 1.8 0.00037 19.8 0.0 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 EGO23872.1 - 4.3e-08 33.2 0.1 0.001 19.1 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGO23872.1 - 4.9e-07 30.1 0.0 0.037 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain EF-hand_5 PF13202.6 EGO23872.1 - 2.9e-06 26.5 4.3 0.0087 15.5 0.1 2.8 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 EGO23872.1 - 3.6e-06 27.5 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGO23872.1 - 2.5e-05 24.8 0.1 0.028 14.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGO23872.1 - 3.8e-05 24.0 0.0 0.11 12.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGO23872.1 - 3.8e-05 23.6 0.1 0.23 11.4 0.0 3.8 4 1 1 5 5 4 1 RsgA GTPase ABC_tran PF00005.27 EGO23872.1 - 8.3e-05 23.1 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 EGO23872.1 - 9.7e-05 22.5 0.7 2.4 8.2 0.0 3.3 2 1 0 3 3 3 1 Dynamin family AAA PF00004.29 EGO23872.1 - 0.00012 22.5 0.0 0.25 11.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO23872.1 - 0.00014 22.0 0.1 0.64 10.2 0.1 2.8 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EGO23872.1 - 0.00014 21.8 0.0 0.45 10.4 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_29 PF13555.6 EGO23872.1 - 0.00015 21.5 0.1 0.098 12.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain VirE PF05272.11 EGO23872.1 - 0.00036 20.3 0.1 4.3 7.0 0.0 3.4 3 1 0 3 3 3 0 Virulence-associated protein E AAA_24 PF13479.6 EGO23872.1 - 0.00048 19.9 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 EGO23872.1 - 0.00099 18.5 0.0 0.045 13.0 0.0 2.3 2 0 0 2 2 2 1 Septin RNA_helicase PF00910.22 EGO23872.1 - 0.0011 19.4 0.0 0.88 10.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SRPRB PF09439.10 EGO23872.1 - 0.0011 18.4 0.1 1.9 7.9 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGO23872.1 - 0.0012 18.6 0.0 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation EF-hand_10 PF14788.6 EGO23872.1 - 0.0015 18.4 3.3 0.0097 15.7 0.1 2.4 2 0 0 2 2 2 1 EF hand ATP_bind_1 PF03029.17 EGO23872.1 - 0.0017 18.2 1.9 5.1 6.8 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGO23872.1 - 0.0017 17.9 0.0 0.076 12.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGO23872.1 - 0.0019 17.8 0.0 0.28 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EGO23872.1 - 0.0032 17.4 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 EGO23872.1 - 0.0046 16.2 0.1 0.42 9.8 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain G-alpha PF00503.20 EGO23872.1 - 0.0047 16.1 0.0 1.7 7.7 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit DUF815 PF05673.13 EGO23872.1 - 0.0059 15.8 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGO23872.1 - 0.0079 16.2 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EGO23872.1 - 0.011 15.5 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SPARC_Ca_bdg PF10591.9 EGO23872.1 - 0.011 16.0 1.2 1.1 9.6 0.0 2.7 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region TsaE PF02367.17 EGO23872.1 - 0.012 15.6 0.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NOG1 PF06858.14 EGO23872.1 - 0.013 15.2 0.4 1.3 8.9 0.2 2.8 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MCM PF00493.23 EGO23872.1 - 0.014 14.5 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EGO23872.1 - 0.024 14.0 0.1 3.7 6.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGO23872.1 - 0.032 14.7 0.1 5.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGO23872.1 - 0.061 12.6 0.0 9.7 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EGO23872.1 - 0.066 12.9 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EGO23872.1 - 0.068 12.5 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 1 0 AIG1 family TniB PF05621.11 EGO23872.1 - 0.083 12.3 0.0 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 EGO23872.1 - 0.1 12.2 0.5 3.5 7.2 0.0 2.9 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EGO23872.1 - 0.13 12.2 0.1 4.4 7.2 0.1 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGO23872.1 - 0.13 12.3 0.0 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGO23872.1 - 0.14 11.9 0.0 2.7 7.7 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Pox_A32 PF04665.12 EGO23872.1 - 0.17 11.3 0.0 8.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Guanylate_kin PF00625.21 EGO23872.1 - 0.2 11.3 0.1 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase DUF4126 PF13548.6 EGO23872.1 - 2 8.1 4.6 0.58 9.8 1.4 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4126) RasGEF PF00617.19 EGO23873.1 - 4.2e-47 160.6 0.0 7.8e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO23873.1 - 1.2e-20 73.6 0.0 3.2e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EGO23873.1 - 2.4e-13 49.7 0.0 4.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO23873.1 - 6.9e-13 48.1 0.0 1.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO23873.1 - 1.4e-12 47.0 0.0 2.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain MBOAT_2 PF13813.6 EGO23874.1 - 3.7e-13 49.6 4.6 4.4e-13 49.3 1.8 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1477 PF07346.11 EGO23874.1 - 0.12 12.6 0.2 0.24 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) p450 PF00067.22 EGO23875.1 - 5.7e-73 246.2 0.0 7.3e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23876.1 - 5.6e-66 223.2 0.0 6.8e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23877.1 - 8.9e-40 136.8 0.0 1.4e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO23878.1 - 4.9e-64 216.8 0.0 6.1e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDC37_N PF03234.14 EGO23879.1 - 7.4e-41 140.1 5.6 1.6e-40 139.0 0.0 3.1 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EGO23879.1 - 5.6e-27 94.0 0.1 2.9e-25 88.5 0.0 2.8 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EGO23879.1 - 1.2e-18 67.1 5.8 1.2e-18 67.1 0.1 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain E2F_CC-MB PF16421.5 EGO23879.1 - 0.025 14.9 0.5 0.19 12.1 0.3 2.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain betaPIX_CC PF16523.5 EGO23879.1 - 0.035 13.9 1.4 0.085 12.7 1.4 1.6 1 0 0 1 1 1 0 betaPIX coiled coil Adaptin_binding PF10199.9 EGO23883.1 - 3.5e-10 40.5 0.2 4.8e-08 33.6 0.2 3.2 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 gag-asp_proteas PF13975.6 EGO23885.1 - 0.0076 16.8 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO23885.1 - 0.018 14.8 0.1 0.6 9.9 0.0 2.2 1 1 1 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO23885.1 - 0.034 14.8 0.0 0.056 14.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 EGO23886.1 - 2.6e-07 30.4 0.5 3.6e-07 30.0 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO23886.1 - 0.0065 16.3 0.7 0.01 15.6 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO23886.1 - 0.0081 15.9 0.6 0.011 15.5 0.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO23886.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Zinc finger domain RseA_N PF03872.13 EGO23890.1 - 0.072 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain HEAT_2 PF13646.6 EGO23895.1 - 7.7e-32 109.6 0.5 1.1e-14 54.6 0.0 4.1 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EGO23895.1 - 8e-23 78.8 0.0 0.00062 20.2 0.0 6.7 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EGO23895.1 - 5.8e-14 51.0 0.1 0.029 14.6 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.23 EGO23895.1 - 9.1e-05 22.4 0.1 0.1 12.7 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGO23895.1 - 0.00013 22.3 1.2 2.9 8.5 0.2 4.9 2 2 2 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EGO23895.1 - 0.0095 16.0 0.0 0.34 10.9 0.0 3.1 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF438 PF04282.13 EGO23895.1 - 0.024 14.6 0.0 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF438) RL10P_insert PF17777.1 EGO23896.1 - 5.5e-23 80.7 0.0 9.3e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGO23896.1 - 2.2e-19 69.4 0.0 3.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RRF PF01765.19 EGO23896.1 - 0.035 14.1 0.4 0.086 12.8 0.4 1.7 1 1 0 1 1 1 0 Ribosome recycling factor UxaC PF02614.14 EGO23896.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Glucuronate isomerase DUF5341 PF17276.2 EGO23896.1 - 0.25 11.5 1.0 0.5 10.5 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5341) Peptidase_S9 PF00326.21 EGO23897.1 - 2.1e-47 161.4 0.2 3e-47 160.8 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGO23897.1 - 0.071 11.8 0.1 3.3 6.3 0.1 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EGO23898.1 - 3.8e-38 131.1 0.1 1.1e-37 129.5 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGO23898.1 - 0.0001 21.1 0.1 0.01 14.5 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF1993 PF09351.10 EGO23898.1 - 0.21 11.7 0.1 0.45 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) FlgM PF04316.13 EGO23899.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF3504 PF12012.8 EGO23900.1 - 0.26 11.2 3.3 0.33 10.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Sec1 PF00995.23 EGO23901.1 - 2e-127 426.9 0.3 2.5e-127 426.5 0.3 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 EGO23901.1 - 3.9e-80 268.9 0.1 8.9e-80 267.7 0.3 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGO23901.1 - 4.7e-22 78.1 0.1 1.3e-21 76.8 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) OGFr_N PF04664.13 EGO23903.1 - 5.6e-59 199.2 0.2 7.3e-59 198.8 0.2 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region 2-oxogl_dehyd_N PF16078.5 EGO23904.1 - 0.036 13.6 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Ank_2 PF12796.7 EGO23906.1 - 0.0001 22.8 0.0 0.00012 22.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO23906.1 - 0.00067 19.9 0.0 0.043 14.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGO23906.1 - 0.00068 20.0 0.0 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGO23906.1 - 0.0052 17.1 0.0 0.022 15.1 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) HA1 PF18239.1 EGO23906.1 - 0.12 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin I FKBP_C PF00254.28 EGO23908.1 - 1.2e-31 108.9 0.0 1.3e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SieB PF14163.6 EGO23909.1 - 1.1 8.7 6.9 3.9 7.0 1.4 2.5 2 1 1 3 3 3 0 Super-infection exclusion protein B Glycolytic PF00274.19 EGO23912.1 - 9.2e-76 254.8 0.0 1.1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Aldo_ket_red PF00248.21 EGO23913.1 - 1.5e-69 234.4 0.2 1.7e-69 234.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF45 PF01863.17 EGO23913.1 - 0.061 13.4 0.1 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 IMPa_N_2 PF18650.1 EGO23913.1 - 0.077 12.2 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Kelch_5 PF13854.6 EGO23915.1 - 2e-16 59.6 3.9 0.00013 21.9 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 EGO23915.1 - 6e-15 54.9 3.5 0.0002 21.5 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGO23915.1 - 1.3e-13 50.3 0.5 0.00039 20.0 0.0 4.2 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGO23915.1 - 2.4e-13 49.5 0.6 0.0029 17.5 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EGO23915.1 - 3e-12 46.5 7.3 6.3e-07 29.5 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EGO23915.1 - 1.4e-08 34.6 8.8 0.04 13.9 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain BTB PF00651.31 EGO23915.1 - 0.1 12.8 0.1 25 5.1 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain HSP70 PF00012.20 EGO23915.1 - 0.59 8.2 4.3 0.85 7.7 4.3 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF1682 PF07946.14 EGO23915.1 - 7.6 5.6 8.7 14 4.8 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-CRD PF17979.1 EGO23916.1 - 6.1e-12 45.9 0.1 6.1e-12 45.9 0.1 2.3 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-RING_2 PF13639.6 EGO23916.1 - 7.7e-05 22.9 17.3 7.7e-05 22.9 17.3 3.5 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO23916.1 - 0.00013 21.8 16.6 0.00013 21.8 16.6 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO23916.1 - 0.0026 17.6 14.2 0.0026 17.6 14.2 3.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 EGO23916.1 - 0.0032 17.4 0.1 0.01 15.8 0.1 1.9 1 0 0 1 1 1 1 PBZ domain zf-RING_5 PF14634.6 EGO23916.1 - 0.35 10.9 28.5 0.13 12.3 16.2 3.0 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_6 PF14835.6 EGO23916.1 - 6.9 6.6 18.5 0.18 11.7 9.5 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C2H2_4 PF13894.6 EGO23919.1 - 3.2e-05 24.4 4.6 0.15 12.9 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO23919.1 - 0.00072 19.9 8.7 0.0075 16.7 0.1 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-BED PF02892.15 EGO23919.1 - 0.0066 16.5 4.4 0.064 13.3 0.4 2.6 2 0 0 2 2 2 1 BED zinc finger zf-C2HE PF16278.5 EGO23919.1 - 0.015 15.7 0.2 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PBP1_TM PF14812.6 EGO23919.1 - 0.15 12.5 0.9 0.42 11.0 0.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-H2C2_5 PF13909.6 EGO23919.1 - 4.7 7.1 12.2 22 4.9 6.4 3.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain IGR PF09597.10 EGO23920.1 - 1.2e-22 79.7 0.2 1.9e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 IGR protein motif Lipoprotein_20 PF13942.6 EGO23920.1 - 0.029 14.3 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Mon1 PF03164.14 EGO23921.1 - 1.5e-114 383.2 0.0 1.7e-114 383.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 BTB PF00651.31 EGO23922.1 - 1.9e-06 28.1 0.1 4.6e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain UPF0172 PF03665.13 EGO23923.1 - 7.4e-59 199.0 0.0 9.1e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Cellulase PF00150.18 EGO23925.1 - 3.8e-17 62.6 1.1 7.2e-17 61.7 1.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EBP PF05241.12 EGO23926.1 - 3.5e-69 231.8 4.1 4.1e-69 231.6 4.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 EGO23926.1 - 0.041 14.3 5.4 0.059 13.8 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) GPI-anchored PF10342.9 EGO23927.1 - 7e-07 29.9 0.0 1.1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EGO23927.1 - 0.04 13.7 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Wzy_C PF04932.15 EGO23932.1 - 0.92 9.1 8.6 4.3 6.9 1.5 2.4 2 1 0 2 2 2 0 O-Antigen ligase GPI-anchored PF10342.9 EGO23933.1 - 2.9e-06 27.9 0.0 3.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Acetyltransf_8 PF13523.6 EGO23934.1 - 0.042 13.5 0.9 0.051 13.3 0.9 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIE-A_C PF11521.8 EGO23934.1 - 0.17 12.2 9.0 0.21 11.9 9.0 1.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha eIF3_subunit PF08597.10 EGO23934.1 - 1.3 8.8 9.6 1.4 8.8 9.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Tcp11 PF05794.13 EGO23935.1 - 8.2e-92 308.6 0.0 9.7e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 ATP-synt_ab PF00006.25 EGO23937.1 - 2.7e-67 226.6 0.0 3.6e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGO23937.1 - 9.7e-13 48.4 0.7 1.8e-12 47.6 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 EGO23937.1 - 0.2 10.5 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFCD_C PF12612.8 EGO23938.1 - 4.1e-43 147.4 0.2 2.8e-42 144.7 0.0 2.6 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGO23938.1 - 1.7e-07 30.9 12.1 0.052 13.8 0.1 7.4 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EGO23938.1 - 8.4e-06 26.1 7.3 0.55 10.7 0.0 5.5 6 1 1 7 7 7 3 HEAT repeats Cnd1 PF12717.7 EGO23938.1 - 2.9e-05 24.2 0.1 0.0019 18.3 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGO23938.1 - 0.0019 16.9 1.6 0.97 7.9 0.0 4.3 4 1 0 4 4 4 1 Adaptin N terminal region HEAT_EZ PF13513.6 EGO23938.1 - 0.014 15.9 8.5 40 4.8 0.0 5.7 5 0 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 EGO23938.1 - 0.04 14.1 0.0 0.75 10.0 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EGO23938.1 - 0.041 14.5 0.0 2.5 8.8 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EGO23938.1 - 0.35 9.9 2.5 4.1 6.4 0.1 2.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.9 EGO23938.1 - 1.4 7.3 4.1 49 2.3 0.9 3.4 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit BUD22 PF09073.10 EGO23939.1 - 3.9e-82 276.9 26.6 4.5e-82 276.7 26.6 1.0 1 0 0 1 1 1 1 BUD22 PP2C PF00481.21 EGO23941.1 - 4.3e-77 259.2 0.0 7.4e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C CHAT PF12770.7 EGO23943.1 - 2.5e-33 115.7 0.0 4.5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EGO23943.1 - 8.4e-13 47.7 16.7 0.068 13.1 0.0 11.8 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO23943.1 - 1e-10 41.7 9.8 2.2 8.6 0.0 12.2 9 4 6 15 15 15 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO23943.1 - 2.6e-09 36.5 12.6 0.4 10.6 0.0 12.0 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO23943.1 - 9e-07 28.6 6.3 1.4 9.2 0.0 9.7 10 1 0 10 10 9 1 Tetratricopeptide repeat Sel1 PF08238.12 EGO23943.1 - 9.6e-07 29.3 0.2 5.9 7.7 0.0 6.7 7 0 0 7 7 7 1 Sel1 repeat TPR_8 PF13181.6 EGO23943.1 - 1.8e-06 27.7 0.1 2.6 8.5 0.0 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO23943.1 - 0.00012 21.7 2.5 15 5.4 0.0 8.1 10 0 0 10 10 10 0 TPR repeat TPR_16 PF13432.6 EGO23943.1 - 0.00091 19.8 0.1 75 4.1 0.0 6.6 7 2 1 8 8 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO23943.1 - 0.0027 18.2 0.1 41 4.8 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat CHAD PF05235.14 EGO23943.1 - 0.0045 17.0 1.5 2.9 7.8 0.1 2.9 3 0 0 3 3 3 2 CHAD domain C2 PF00168.30 EGO23943.1 - 0.0061 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain TPR_14 PF13428.6 EGO23943.1 - 0.0071 17.1 9.7 3.3 8.8 0.0 8.3 11 0 0 11 11 9 1 Tetratricopeptide repeat Glyco_hydro_71 PF03659.14 EGO23946.1 - 6.1e-132 440.0 7.9 7.2e-132 439.7 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HA2 PF04408.23 EGO23947.1 - 2.9e-26 91.9 0.1 2.9e-26 91.9 0.1 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO23947.1 - 1.4e-19 70.2 0.0 3.6e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO23947.1 - 1.3e-10 41.6 0.0 5e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO23947.1 - 1.2e-07 31.7 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO23947.1 - 0.00013 22.2 0.0 0.0005 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGO23947.1 - 0.042 13.9 0.0 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGO23947.1 - 0.046 13.4 0.7 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGO23947.1 - 0.052 12.9 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 KaiC SEN1_N PF12726.7 EGO23948.1 - 5.4e-178 593.6 0.0 7.4e-178 593.2 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EGO23948.1 - 9e-72 242.0 1.5 1.8e-71 241.0 1.5 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGO23948.1 - 6.7e-58 195.6 0.0 1.3e-57 194.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO23948.1 - 8.3e-09 35.4 1.0 8.8e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGO23948.1 - 7.9e-08 32.8 4.9 7.2e-07 29.6 4.9 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGO23948.1 - 5.4e-05 23.0 0.4 0.54 10.0 0.2 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EGO23948.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EGO23948.1 - 0.043 12.9 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 EGO23948.1 - 0.057 13.2 0.4 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EGO23948.1 - 0.067 12.8 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO23948.1 - 0.11 12.8 0.1 0.85 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Sipho_Gp157 PF05565.11 EGO23948.1 - 0.12 12.4 3.6 0.33 10.9 3.6 1.7 1 0 0 1 1 1 0 Siphovirus Gp157 AAA_22 PF13401.6 EGO23948.1 - 0.14 12.4 2.4 0.83 9.9 0.5 3.1 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 EGO23948.1 - 0.19 12.2 0.9 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Translin PF01997.16 EGO23949.1 - 1.7e-49 168.6 0.0 1.9e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1664 PF07889.12 EGO23949.1 - 0.0021 18.1 0.4 0.017 15.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) XhlA PF10779.9 EGO23949.1 - 0.14 12.4 2.8 3.9 7.7 1.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF1325 PF07039.11 EGO23950.1 - 2.4e-41 140.9 0.0 3.2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain HSP20 PF00011.21 EGO23951.1 - 1.2e-15 57.5 0.1 1.9e-12 47.2 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO23951.1 - 6.2e-11 41.7 0.1 2.3e-10 39.9 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 EGO23951.1 - 0.033 14.3 0.7 0.061 13.4 0.2 1.5 1 1 0 1 1 1 0 GvpH TIG PF01833.24 EGO23951.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 IPT/TIG domain CBFD_NFYB_HMF PF00808.23 EGO23952.1 - 1.1e-08 35.2 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO23952.1 - 0.00018 21.9 2.2 0.00023 21.5 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF5536 PF17688.1 EGO23952.1 - 0.076 12.9 1.7 0.1 12.5 0.1 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF5536) DIOX_N PF14226.6 EGO23954.1 - 3.5e-27 95.5 0.0 5.7e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO23954.1 - 5.9e-15 55.6 0.0 1.9e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA_bind PF01588.20 EGO23955.1 - 5.1e-29 100.2 0.0 8.7e-29 99.5 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 EGO23955.1 - 7.4e-05 22.9 1.8 7.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO23955.1 - 8.3e-05 22.7 2.9 0.00018 21.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.12 EGO23955.1 - 0.03 14.6 1.9 0.041 14.2 1.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GST_C_2 PF13410.6 EGO23955.1 - 0.037 14.1 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NARP1 PF12569.8 EGO23955.1 - 0.12 11.3 7.6 0.16 10.8 7.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GST_C_6 PF17171.4 EGO23955.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Med19 PF10278.9 EGO23955.1 - 0.41 10.5 10.7 0.62 10.0 10.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Totivirus_coat PF05518.11 EGO23955.1 - 0.43 8.6 2.8 0.59 8.1 2.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein RNA_pol_Rpc4 PF05132.14 EGO23955.1 - 0.88 10.0 9.4 1.4 9.3 9.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Spore_coat_CotO PF14153.6 EGO23955.1 - 1.2 9.0 10.9 2 8.3 10.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 EGO23955.1 - 2.7 7.7 10.7 4.2 7.1 10.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 EGO23955.1 - 9.9 5.3 8.7 14 4.8 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AA_permease_2 PF13520.6 EGO23956.1 - 8.9e-58 196.1 54.6 1.1e-57 195.9 54.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO23956.1 - 5.9e-17 61.4 51.7 1.9e-16 59.8 51.7 1.6 1 1 0 1 1 1 1 Amino acid permease PepSY_TM PF03929.16 EGO23956.1 - 0.088 12.5 4.6 0.29 10.8 4.6 1.9 1 0 0 1 1 1 0 PepSY-associated TM region Ribosomal_L6 PF00347.23 EGO23957.1 - 4.4e-24 84.9 0.0 4.6e-12 46.4 0.0 2.4 2 1 0 2 2 2 2 Ribosomal protein L6 ATP-synt_C PF00137.21 EGO23958.1 - 1.9e-30 105.0 32.3 2e-18 66.4 12.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_J PF04911.12 EGO23958.1 - 3.1 7.4 5.5 12 5.6 0.4 2.6 2 0 0 2 2 2 0 ATP synthase j chain zf-CCHC_3 PF13917.6 EGO23959.1 - 7.3e-19 67.5 0.4 1.2e-18 66.7 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO23959.1 - 0.041 14.0 0.4 0.07 13.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF5106 PF17127.4 EGO23960.1 - 0.031 14.5 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) PEMT PF04191.13 EGO23961.1 - 6.7e-06 26.5 1.3 8.9e-06 26.1 0.3 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EGO23961.1 - 9.5e-05 22.7 0.7 9.5e-05 22.7 0.7 1.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 EGO23961.1 - 0.011 15.2 0.5 0.14 11.7 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1295) SIKE PF05769.11 EGO23962.1 - 2.7e-05 24.2 14.6 0.001 19.1 14.6 2.3 1 1 0 1 1 1 1 SIKE family DUF2959 PF11172.8 EGO23962.1 - 0.0063 16.7 3.8 0.0099 16.0 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Nsp1_C PF05064.13 EGO23962.1 - 0.0097 15.7 2.7 0.0098 15.7 0.5 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region TACC_C PF05010.14 EGO23962.1 - 0.011 15.5 4.0 0.011 15.5 4.0 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal OmpH PF03938.14 EGO23962.1 - 0.026 14.9 2.4 0.026 14.9 2.4 2.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 EGO23962.1 - 0.048 13.7 2.1 0.048 13.7 2.1 2.9 3 0 0 3 3 3 0 bZIP transcription factor RasGAP_C PF03836.15 EGO23962.1 - 0.07 13.3 3.7 0.15 12.2 3.7 1.7 1 1 0 1 1 1 0 RasGAP C-terminus NYD-SP28_assoc PF14775.6 EGO23962.1 - 0.77 9.9 8.6 2.3 8.4 0.8 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain FUSC PF04632.12 EGO23962.1 - 1.4 7.4 8.5 2.3 6.6 1.1 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family JIP_LZII PF16471.5 EGO23962.1 - 1.4 9.2 6.7 0.47 10.7 1.5 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 EGO23962.1 - 1.7 8.9 9.1 0.23 11.6 1.3 3.0 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 EGO23962.1 - 2.2 8.4 7.7 6.5 6.9 0.7 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF3552 PF12072.8 EGO23962.1 - 2.4 7.5 9.4 0.38 10.1 3.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) FAM184 PF15665.5 EGO23962.1 - 3.3 7.4 13.2 0.56 9.9 7.2 1.9 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Jnk-SapK_ap_N PF09744.9 EGO23962.1 - 3.8 7.7 14.7 0.94 9.7 10.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Presenilin PF01080.17 EGO23964.1 - 0.079 11.7 0.3 0.096 11.4 0.3 1.0 1 0 0 1 1 1 0 Presenilin PHD PF00628.29 EGO23965.1 - 2.9e-07 30.3 5.2 5.9e-07 29.3 5.2 1.5 1 1 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EGO23965.1 - 0.0035 17.0 2.4 0.0035 17.0 2.4 1.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EGO23965.1 - 0.0082 16.0 2.5 0.0082 16.0 2.5 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 EGO23965.1 - 0.36 10.4 10.5 2.5 7.7 0.3 3.2 3 0 0 3 3 3 0 PHD-finger C1_2 PF03107.16 EGO23965.1 - 0.64 10.4 6.9 0.33 11.3 2.2 2.2 2 0 0 2 2 2 0 C1 domain F-actin_cap_A PF01267.17 EGO23966.1 - 9.1e-104 346.6 0.0 1e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ICL PF00463.21 EGO23967.1 - 1e-255 849.3 0.1 1.1e-255 849.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGO23967.1 - 8.9e-10 38.4 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.21 EGO23968.1 - 5.6e-30 104.4 6.9 5.6e-30 104.4 6.9 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 DKNYY PF13644.6 EGO23969.1 - 0.0035 18.1 0.3 0.0038 18.0 0.3 1.0 1 0 0 1 1 1 1 DKNYY family DUF4939 PF16297.5 EGO23969.1 - 0.03 14.2 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EGO23970.1 - 0.00097 19.1 4.1 0.0016 18.5 4.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO23970.1 - 0.92 9.4 3.8 1.5 8.7 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle HTH_23 PF13384.6 EGO23972.1 - 0.00047 19.9 1.4 0.14 12.0 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 EGO23972.1 - 0.0091 15.7 0.4 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Bac_DnaA_C PF08299.11 EGO23972.1 - 0.091 12.8 0.4 0.99 9.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix GerE PF00196.19 EGO23972.1 - 0.15 11.6 0.0 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Myb_DNA-bind_3 PF12776.7 EGO23973.1 - 3.1e-07 31.3 0.1 6.4e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO23973.1 - 0.015 15.7 0.3 0.044 14.2 0.3 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain NPCBM PF08305.11 EGO23973.1 - 0.11 12.7 0.2 0.27 11.4 0.1 1.6 1 1 1 2 2 2 0 NPCBM/NEW2 domain dCMP_cyt_deam_1 PF00383.23 EGO23974.1 - 1.7e-07 31.0 0.0 3.2e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO23974.1 - 4.8e-05 23.1 0.0 7.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGO23974.1 - 0.036 14.1 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Malic_M PF03949.15 EGO23975.1 - 1.2e-92 309.8 0.0 1.6e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGO23975.1 - 3.1e-65 219.4 0.0 5.3e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MRP-L20 PF12824.7 EGO23976.1 - 7.7e-28 97.7 8.4 1.3e-27 96.9 8.4 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 dsrm PF00035.26 EGO23976.1 - 0.12 13.2 0.2 0.32 11.7 0.2 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF1509 PF07420.11 EGO23977.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Hemerythrin PF01814.23 EGO23978.1 - 7.6e-13 49.2 3.5 1.3e-12 48.5 3.5 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RTT107_BRCT_5 PF16770.5 EGO23978.1 - 0.05 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Spc7 PF08317.11 EGO23978.1 - 0.075 11.9 1.2 0.11 11.4 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GST_N PF02798.20 EGO23979.1 - 1.1e-12 48.1 0.0 2.1e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO23979.1 - 2.2e-12 47.0 0.0 5.3e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO23979.1 - 2.4e-10 40.3 0.0 5.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO23979.1 - 2.3e-09 37.5 0.0 4.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO23979.1 - 4.7e-09 36.3 0.0 1.9e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO23979.1 - 5.8e-08 32.9 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HAT_KAT11 PF08214.11 EGO23980.1 - 5.9e-15 55.4 0.0 8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cullin PF00888.22 EGO23981.1 - 1.4e-187 625.1 18.5 1.9e-187 624.7 18.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGO23981.1 - 1.1e-15 57.3 1.7 5.1e-15 55.3 1.7 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain GntR PF00392.21 EGO23981.1 - 0.019 14.6 0.2 0.044 13.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ubie_methyltran PF01209.18 EGO23982.1 - 9.8e-77 257.4 0.0 1.2e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGO23982.1 - 1.4e-13 51.3 0.0 3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO23982.1 - 7.2e-11 42.1 0.0 1.2e-10 41.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO23982.1 - 2.1e-10 41.1 0.0 3.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO23982.1 - 8.1e-09 36.1 0.0 1.5e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO23982.1 - 3.7e-07 30.1 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cullin PF00888.22 EGO23984.1 - 1.8e-38 132.6 1.0 4.4e-20 71.9 0.1 2.1 1 1 1 2 2 2 2 Cullin family Cullin PF00888.22 EGO23985.1 - 3.3e-46 158.2 4.2 3.9e-46 157.9 4.2 1.0 1 0 0 1 1 1 1 Cullin family DUF4535 PF15054.6 EGO23985.1 - 0.022 14.5 0.1 0.065 13.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Fcf2 PF08698.11 EGO23987.1 - 8.7e-29 99.8 0.3 2.7e-28 98.2 0.0 1.9 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing FlaG PF03646.15 EGO23987.1 - 0.015 15.4 3.2 0.035 14.3 3.2 1.5 1 0 0 1 1 1 0 FlaG protein AF-4 PF05110.13 EGO23987.1 - 0.045 11.9 8.6 0.06 11.4 8.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Fungal_trans PF04082.18 EGO23988.1 - 5.4e-07 28.9 0.2 4.6e-06 25.9 0.1 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO23988.1 - 2.4e-05 24.3 5.7 4e-05 23.6 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 EGO23989.1 - 1e-08 35.3 0.0 4.3e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EGO23989.1 - 1.8e-08 34.2 0.0 6.7e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EGO23989.1 - 1.1e-07 31.3 0.1 7.5e-06 25.2 0.1 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGO23989.1 - 3.4e-07 29.6 0.0 9.7e-07 28.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO23989.1 - 5.1e-06 26.1 0.7 0.00045 19.7 1.1 3.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO23989.1 - 0.00098 18.4 1.5 0.44 9.7 0.4 2.7 1 1 1 2 2 2 2 Male sterility protein DUF2462 PF09495.10 EGO23990.1 - 2.7e-21 76.1 11.3 2.7e-21 76.1 11.3 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) AOX PF01786.17 EGO23991.1 - 1.5e-98 328.7 0.0 1.9e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase PH_4 PF15404.6 EGO23992.1 - 9.3e-21 74.4 1.1 7e-17 61.8 0.6 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain zf-Nse PF11789.8 EGO23993.1 - 3.2e-16 58.9 0.1 5.7e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGO23993.1 - 3.9e-05 23.6 0.1 6.9e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO23993.1 - 0.00088 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RAG1 PF10426.9 EGO23993.1 - 0.0034 17.5 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Recombination-activating protein 1 zinc-finger domain U-box PF04564.15 EGO23993.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-C3HC4 PF00097.25 EGO23993.1 - 0.025 14.4 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO23993.1 - 0.071 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosom_S12_S23 PF00164.25 EGO23994.1 - 3.3e-33 113.7 1.7 4.1e-33 113.4 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MRP-L47 PF06984.13 EGO23996.1 - 7.7e-21 74.0 0.1 1.3e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EGO23996.1 - 6.2e-05 22.9 3.4 6.7e-05 22.8 1.0 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein Complex1_LYR PF05347.15 EGO23997.1 - 3.1e-10 39.9 0.5 5.2e-10 39.2 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO23997.1 - 0.00026 21.7 0.1 0.00031 21.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF3677 PF12432.8 EGO23997.1 - 0.049 13.9 0.0 0.083 13.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3677) Complex1_LYR_1 PF13232.6 EGO23997.1 - 0.24 12.0 3.2 2.8 8.6 0.1 2.2 1 1 1 2 2 2 0 Complex1_LYR-like SQS_PSY PF00494.19 EGO23998.1 - 1.9e-47 162.0 0.0 2.2e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF5539 PF17693.1 EGO23999.1 - 0.28 10.8 1.7 0.49 10.0 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5539) PBP1_TM PF14812.6 EGO23999.1 - 1.6 9.2 11.3 0.96 9.9 0.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal vATP-synt_AC39 PF01992.16 EGO24001.1 - 2.2e-115 385.7 0.2 2.5e-115 385.6 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 EGO24001.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain CRAL_TRIO PF00650.20 EGO24002.1 - 2e-28 99.1 0.0 3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO24002.1 - 5.7e-08 32.8 0.0 1.8e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain zf-CCHC PF00098.23 EGO24004.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO24004.1 - 0.0083 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO24004.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain Abhydrolase_6 PF12697.7 EGO24005.1 - 1.3e-16 61.9 0.0 1.6e-16 61.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO24005.1 - 2.5e-14 53.6 0.1 3.8e-13 49.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO24005.1 - 4.3e-13 49.1 0.0 1.8e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 EGO24005.1 - 0.0044 16.5 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 1 Serine carboxypeptidase FSH1 PF03959.13 EGO24005.1 - 0.01 15.5 0.0 2.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGO24005.1 - 0.085 12.3 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGO24006.1 - 4.7e-14 52.6 0.0 1.7e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO24006.1 - 2.8e-12 47.7 0.0 3.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO24006.1 - 1.6e-10 40.7 0.0 1.1e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EGO24006.1 - 0.014 15.1 0.0 0.064 12.9 0.0 2.0 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 EGO24006.1 - 0.036 13.0 0.0 0.073 12.0 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 EGO24006.1 - 0.051 13.4 0.0 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_6 PF12697.7 EGO24008.1 - 8.7e-11 42.8 0.4 1.4e-10 42.2 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO24008.1 - 1.6e-07 31.2 0.1 3.6e-07 30.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO24008.1 - 7.1e-05 22.2 0.1 0.00031 20.1 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF3827 PF12877.7 EGO24009.1 - 0.82 8.0 7.4 0.91 7.8 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Zip PF02535.22 EGO24009.1 - 1 8.5 3.3 1.1 8.4 3.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CCDC106 PF15794.5 EGO24009.1 - 1 9.0 7.9 1.2 8.8 7.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 EGO24009.1 - 2.2 7.0 4.2 2.3 6.9 4.2 1.0 1 0 0 1 1 1 0 Presenilin E1_dh PF00676.20 EGO24011.1 - 9e-89 297.4 0.0 1.1e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Spuma_A9PTase PF03539.14 EGO24011.1 - 0.17 12.0 0.6 0.32 11.1 0.6 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) SMC_N PF02463.19 EGO24012.1 - 3.1e-16 59.5 14.6 1.4e-15 57.3 14.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO24012.1 - 3.2e-10 40.8 24.7 3.2e-10 40.8 24.7 5.7 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EGO24012.1 - 1.9e-07 31.2 1.0 0.00052 19.9 0.6 2.9 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGO24012.1 - 3.8e-07 30.2 6.9 3.8e-07 30.2 6.9 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EGO24012.1 - 0.00039 20.1 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Nucleolin_bd PF16725.5 EGO24012.1 - 0.045 13.4 2.5 14 5.5 0.1 3.5 2 1 1 3 3 3 0 Nucleolin binding domain FlaC_arch PF05377.11 EGO24012.1 - 1.4 9.4 7.1 4 7.9 1.4 3.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Peptidase_C48 PF02902.19 EGO24014.1 - 2.4e-14 53.7 0.1 1e-12 48.4 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Mt_ATP-synt_B PF05405.14 EGO24014.1 - 0.13 11.8 0.4 0.74 9.4 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mur_ligase_M PF08245.12 EGO24015.1 - 0.00029 20.9 0.0 0.0014 18.7 0.0 1.9 2 1 0 2 2 2 1 Mur ligase middle domain SKN1 PF03935.15 EGO24019.1 - 2.7e-194 646.2 3.8 3.2e-194 646.0 3.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ThiF PF00899.21 EGO24020.1 - 8.9e-30 103.8 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2924 PF11149.8 EGO24020.1 - 0.081 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Fungal_trans PF04082.18 EGO24021.1 - 7.2e-20 71.1 0.0 1.2e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO24021.1 - 8.1e-08 32.3 10.6 1.6e-07 31.3 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 EGO24022.1 - 0.00078 19.6 0.1 0.031 14.5 0.0 3.3 2 2 2 4 4 4 1 PPR repeat family DUF4072 PF13284.6 EGO24022.1 - 0.028 14.8 0.6 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) PPR_3 PF13812.6 EGO24022.1 - 0.057 13.5 0.0 1.9 8.6 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain gag_pre-integrs PF13976.6 EGO24025.1 - 1.7e-05 24.6 0.2 1.7e-05 24.6 0.2 1.5 2 0 0 2 2 2 1 GAG-pre-integrase domain IBR PF01485.21 EGO24026.1 - 2.2e-14 53.4 47.6 1.1e-06 28.8 5.3 4.4 4 0 0 4 4 4 4 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGO24026.1 - 0.00056 19.7 6.7 0.00056 19.7 6.7 4.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO24026.1 - 0.0006 19.6 1.4 0.0006 19.6 1.4 4.8 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO24026.1 - 0.011 16.1 5.8 0.011 16.1 5.8 5.4 4 2 1 5 5 5 0 Ring finger domain GRASP55_65 PF04495.14 EGO24027.1 - 5.2e-61 205.0 0.0 1.4e-44 151.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EGO24027.1 - 0.00011 22.5 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EGO24027.1 - 0.00044 20.0 0.1 0.0037 17.1 0.0 2.4 3 0 0 3 3 3 1 PDZ domain MATH PF00917.26 EGO24028.1 - 5.9e-07 29.6 0.3 1.2e-06 28.7 0.3 1.5 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 EGO24028.1 - 0.00012 22.2 0.1 1 9.6 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain RRM_1 PF00076.22 EGO24029.1 - 8.4e-50 166.5 1.4 8.9e-18 63.9 0.1 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO24029.1 - 1.4e-09 37.7 0.0 0.057 13.3 0.0 4.0 4 0 0 4 4 4 3 Occluded RNA-recognition motif Suf PF05843.14 EGO24029.1 - 6.8e-07 29.6 0.6 1.5e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) RRM_7 PF16367.5 EGO24029.1 - 0.00014 21.9 0.7 12 6.1 0.0 4.7 4 1 1 5 5 5 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGO24029.1 - 0.00026 20.9 0.0 0.59 10.2 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_19 PF14559.6 EGO24029.1 - 0.048 14.2 0.7 0.28 11.7 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Nup35_RRM PF05172.13 EGO24029.1 - 0.081 12.9 0.0 2.1 8.4 0.0 2.7 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif adh_short_C2 PF13561.6 EGO24031.1 - 2e-39 135.6 1.2 9.8e-38 130.0 1.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO24031.1 - 4.8e-36 124.1 0.4 4.8e-36 124.1 0.4 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGO24031.1 - 1e-06 28.8 0.4 2.3e-06 27.6 0.4 1.5 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 EGO24031.1 - 0.016 15.8 0.3 0.046 14.3 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGO24031.1 - 0.15 11.9 0.3 0.3 11.0 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGO24031.1 - 0.18 11.9 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EGO24032.1 - 9.9e-48 163.2 0.9 5.9e-41 140.9 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EGO24032.1 - 5.2e-08 32.7 0.4 5.6e-05 22.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 EGO24032.1 - 1.8e-06 27.8 8.2 3.2e-06 27.0 3.3 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGO24032.1 - 5.1e-05 22.5 7.4 0.00016 20.9 0.9 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGO24032.1 - 0.00025 20.4 0.2 0.074 12.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO24032.1 - 0.00038 19.3 0.9 0.099 11.3 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EGO24032.1 - 0.0095 16.1 0.9 0.036 14.3 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGO24032.1 - 0.028 13.7 0.5 0.9 8.7 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO24032.1 - 0.095 11.7 0.3 0.44 9.5 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein PLDc_2 PF13091.6 EGO24033.1 - 4.8e-14 52.4 0.0 8.6e-07 28.9 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EGO24033.1 - 7.3e-14 51.7 1.1 1.2e-10 41.4 0.3 2.9 2 0 0 2 2 2 2 PX domain PLDc PF00614.22 EGO24033.1 - 2.4e-13 49.7 0.7 3.4e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PH PF00169.29 EGO24033.1 - 0.14 12.7 0.8 2.2 8.8 0.8 2.4 1 1 0 1 1 1 0 PH domain HEPN_RES_NTD1 PF18870.1 EGO24033.1 - 0.15 12.2 1.0 0.31 11.2 0.3 2.0 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 PROCN PF08083.11 EGO24035.1 - 6.6e-233 772.7 9.3 9.9e-233 772.1 7.8 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGO24035.1 - 4.4e-126 419.1 0.3 1.1e-125 417.8 0.2 1.7 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGO24035.1 - 1.1e-87 292.0 5.3 1.2e-87 291.9 2.3 2.5 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGO24035.1 - 6.9e-85 282.6 2.4 6.9e-85 282.6 2.4 2.5 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGO24035.1 - 7.7e-73 242.9 0.1 1.5e-72 242.0 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EGO24035.1 - 3e-46 155.7 0.4 6.4e-46 154.6 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EGO24035.1 - 8.1e-40 135.6 0.0 1.9e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 EGO24035.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TMEM206 PF15122.6 EGO24038.1 - 0.019 14.1 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family Presenilin PF01080.17 EGO24042.1 - 1.7 7.3 7.5 2.3 6.9 7.5 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EGO24042.1 - 8 4.4 13.1 9.9 4.1 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rhodanese PF00581.20 EGO24043.1 - 1.2e-10 41.9 0.0 1.4e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain But2 PF09792.9 EGO24044.1 - 9.7e-08 32.5 0.3 2.5e-07 31.2 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Porin_3 PF01459.22 EGO24047.1 - 6.6e-74 248.8 4.6 7.4e-74 248.6 4.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin Cofilin_ADF PF00241.20 EGO24048.1 - 1.7e-39 134.3 0.2 1.9e-39 134.2 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CH PF00307.31 EGO24049.1 - 1.3e-46 157.2 0.0 1.4e-23 83.2 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EGO24049.1 - 7.8e-15 54.7 0.0 2.5e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EGO24049.1 - 1.2e-10 41.1 0.1 1.1e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 EGO24049.1 - 0.006 17.1 0.6 1.3 9.6 0.1 2.8 2 1 0 2 2 2 1 Spectrin repeat EF-hand_6 PF13405.6 EGO24049.1 - 0.012 15.4 0.0 0.09 12.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Herpes_UL17 PF04559.12 EGO24049.1 - 0.015 14.1 0.4 0.022 13.6 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein EF-hand_8 PF13833.6 EGO24049.1 - 0.024 14.5 0.0 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair CNTF PF01110.17 EGO24049.1 - 0.063 12.6 2.3 0.15 11.4 0.2 2.4 2 0 0 2 2 2 0 Ciliary neurotrophic factor Baculo_PEP_C PF04513.12 EGO24049.1 - 0.35 10.9 5.6 0.1 12.6 0.8 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_14 PF17959.1 EGO24049.1 - 1 9.8 3.2 17 5.8 0.0 3.5 4 1 0 4 4 4 0 EF-hand domain POB3_N PF17292.2 EGO24050.1 - 2.1e-33 114.6 0.2 3.4e-29 101.1 0.1 2.9 2 1 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 EGO24050.1 - 5.5e-26 90.3 0.0 2.7e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EGO24050.1 - 8.5e-22 77.4 0.1 1.2e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like WD40 PF00400.32 EGO24052.1 - 0.00031 21.5 0.0 0.92 10.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat TxDE PF18711.1 EGO24052.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme DUF3082 PF11282.8 EGO24054.1 - 1.4 9.2 6.8 2.3 8.5 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) MIP PF00230.20 EGO24055.1 - 2.6e-50 171.2 4.9 3.3e-50 170.9 4.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.20 EGO24055.1 - 0.0023 18.1 0.8 0.0023 18.1 0.8 2.3 4 0 0 4 4 4 1 EamA-like transporter family Snapin_Pallidin PF14712.6 EGO24056.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Snapin/Pallidin SPT6_acidic PF14632.6 EGO24057.1 - 1.1e-06 29.1 3.6 1.4e-06 28.8 3.6 1.1 1 0 0 1 1 1 1 Acidic N-terminal SPT6 mRNA_triPase PF02940.15 EGO24058.1 - 4.3e-54 183.5 0.0 5.1e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Zip PF02535.22 EGO24059.1 - 3.2e-28 98.9 9.8 6.6e-27 94.6 9.8 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter OCIA PF07051.11 EGO24059.1 - 0.047 13.7 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) PhyH PF05721.13 EGO24060.1 - 0.0001 22.6 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 EGO24061.1 - 0.00029 21.2 0.0 0.94 9.7 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Anthrax-tox_M PF09156.10 EGO24061.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain PhyH PF05721.13 EGO24062.1 - 0.0088 16.3 0.0 0.37 11.0 0.0 2.3 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Mit_KHE1 PF10173.9 EGO24064.1 - 4.3e-59 199.8 0.1 5.5e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GFO_IDH_MocA PF01408.22 EGO24065.1 - 1.2e-23 84.2 0.0 1.9e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO24065.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DNAPolymera_Pol PF11590.8 EGO24065.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Lipase_3 PF01764.25 EGO24066.1 - 5.5e-23 81.4 0.0 7.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO24066.1 - 0.00044 20.9 0.1 0.00044 20.9 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO24066.1 - 0.00047 19.9 0.0 0.00073 19.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.12 EGO24066.1 - 0.0091 15.9 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 EGO24066.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EGO24066.1 - 0.043 13.5 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ysc84 PF04366.12 EGO24069.1 - 9.3e-45 151.5 0.0 1.6e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Phosphodiest PF01663.22 EGO24070.1 - 2.4e-73 247.8 0.7 2.9e-73 247.5 0.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase CwsA PF10814.8 EGO24070.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Prenyltransf PF01255.19 EGO24071.1 - 4.5e-75 252.0 0.0 5.5e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.6 EGO24071.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) LRR_6 PF13516.6 EGO24072.1 - 6.3e-12 44.5 11.1 0.17 12.0 0.1 7.9 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EGO24072.1 - 0.033 14.6 15.2 2.1 8.9 0.9 5.3 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO24072.1 - 0.4 10.5 11.2 20 5.0 2.4 5.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EGO24072.1 - 0.48 11.2 8.5 41 5.3 0.3 5.4 4 2 0 4 4 4 0 Leucine Rich Repeat Flavoprotein PF02441.19 EGO24074.1 - 4.3e-51 172.8 0.0 4.9e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Mob1_phocein PF03637.17 EGO24075.1 - 2.1e-67 226.3 0.8 2.6e-67 226.1 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_15 PF00723.21 EGO24079.1 - 1e-94 317.9 0.2 1.2e-94 317.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EGO24079.1 - 1e-28 99.1 2.7 2.1e-28 98.0 2.7 1.6 1 0 0 1 1 1 1 Starch binding domain zf-CCHH PF10283.9 EGO24080.1 - 0.0039 17.1 5.6 0.0075 16.2 5.6 1.5 1 0 0 1 1 1 1 PBZ domain zf-RING_2 PF13639.6 EGO24081.1 - 4.8e-11 42.8 3.1 4.8e-11 42.8 3.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGO24081.1 - 2.5e-10 39.9 2.3 6.3e-10 38.6 2.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 EGO24081.1 - 6.4e-08 32.5 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 EGO24081.1 - 2e-05 24.3 2.1 5.3e-05 23.0 2.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO24081.1 - 3.6e-05 23.6 1.0 7.3e-05 22.6 1.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO24081.1 - 6.7e-05 22.7 1.5 0.00015 21.6 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO24081.1 - 0.0022 18.0 3.4 0.014 15.4 0.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGO24081.1 - 0.0027 17.9 8.1 0.0073 16.6 5.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EGO24081.1 - 0.0035 16.9 1.8 0.0069 16.0 1.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EGO24081.1 - 0.0042 16.9 1.4 0.011 15.6 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGO24081.1 - 0.042 13.9 0.7 0.14 12.2 0.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EGO24081.1 - 0.069 13.3 3.2 0.57 10.4 3.0 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 EGO24081.1 - 1.1 9.2 5.4 0.31 11.0 1.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CCCH PF00642.24 EGO24082.1 - 7.5e-20 70.4 30.1 4.3e-10 39.2 1.9 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO24082.1 - 5.5e-15 54.8 37.3 6.3e-07 29.3 4.4 3.3 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 EGO24082.1 - 3.6e-11 42.6 29.2 8.5e-07 28.6 3.2 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 EGO24082.1 - 6.8e-10 39.6 9.2 0.0075 17.0 0.1 3.4 3 0 0 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 EGO24082.1 - 0.0028 18.1 30.3 0.068 13.7 5.1 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGO24082.1 - 0.12 12.5 15.4 5.6 7.2 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger containing family LUC7 PF03194.15 EGO24082.1 - 0.22 11.1 0.5 0.53 9.9 0.5 1.6 1 0 0 1 1 1 0 LUC7 N_terminus Heme_oxygenase PF01126.20 EGO24083.1 - 2e-27 96.3 0.0 2.6e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase Asp PF00026.23 EGO24084.1 - 2.6e-19 69.8 7.8 1.1e-13 51.3 1.7 3.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Orthoreo_P10 PF07204.11 EGO24084.1 - 0.0025 17.7 0.1 0.0059 16.5 0.1 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM132D_C PF15706.5 EGO24084.1 - 0.016 14.9 0.0 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Tetraspanin PF00335.20 EGO24084.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family TAXi_N PF14543.6 EGO24084.1 - 0.026 14.7 4.2 1 9.6 0.9 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal WBP-1 PF11669.8 EGO24084.1 - 0.052 14.2 0.3 0.17 12.5 0.1 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 Asp_protease_2 PF13650.6 EGO24084.1 - 0.078 13.6 1.4 0.19 12.4 0.3 2.4 2 1 0 2 2 2 0 Aspartyl protease stn_TNFRSF12A PF12191.8 EGO24084.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain gag-asp_proteas PF13975.6 EGO24084.1 - 0.18 12.4 0.4 3.6 8.2 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 EGO24085.1 - 3.4e-18 66.1 0.3 2.9e-14 53.2 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 EGO24085.1 - 7.9e-05 23.1 1.1 0.029 14.9 0.2 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO24085.1 - 0.00015 22.4 2.0 0.01 16.5 0.5 3.3 3 0 0 3 3 3 1 Aspartyl protease Pox_A14 PF05767.12 EGO24085.1 - 0.02 15.0 0.3 0.21 11.8 0.1 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 KRE1 PF17056.5 EGO24085.1 - 1.3 8.8 5.7 0.67 9.7 0.6 2.9 3 0 0 3 3 3 0 Killer toxin-resistance protein 1 p450 PF00067.22 EGO24086.1 - 6.2e-72 242.8 0.0 7e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF416 PF04222.12 EGO24089.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF416) Asp PF00026.23 EGO24090.1 - 7e-15 55.2 0.0 1.8e-12 47.3 0.0 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease RCR PF12273.8 EGO24090.1 - 0.00015 22.4 0.1 0.00035 21.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red gag-asp_proteas PF13975.6 EGO24090.1 - 0.00054 20.5 0.4 0.047 14.3 0.0 3.2 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO24090.1 - 0.0068 17.0 1.3 0.038 14.6 0.1 2.8 4 0 0 4 4 4 1 Aspartyl protease TMEM154 PF15102.6 EGO24090.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 EGO24090.1 - 0.021 15.1 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EGO24090.1 - 0.097 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 EGO24090.1 - 0.099 13.1 0.3 0.23 11.9 0.3 1.6 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Orf78 PF06024.12 EGO24090.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF1180 PF06679.12 EGO24090.1 - 0.29 11.5 1.9 0.39 11.1 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SCIMP PF15050.6 EGO24090.1 - 0.31 11.5 0.9 2.8 8.4 1.3 2.2 2 0 0 2 2 2 0 SCIMP protein Adeno_E3_CR2 PF02439.15 EGO24090.1 - 1.1 9.1 8.3 1.9 8.3 8.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMIE PF16038.5 EGO24090.1 - 2.7 7.9 4.4 4.9 7.1 4.4 1.3 1 0 0 1 1 1 0 TMIE protein HNH_2 PF13391.6 EGO24091.1 - 1.7e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 HNH endonuclease Dynactin_p62 PF05502.13 EGO24092.1 - 1.8e-73 248.0 7.4 2.8e-44 151.7 6.3 2.1 1 1 1 2 2 2 2 Dynactin p62 family DUF2235 PF09994.9 EGO24092.1 - 0.15 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF898 PF05987.13 EGO24093.1 - 0.049 12.7 0.5 0.068 12.2 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) TMEM192 PF14802.6 EGO24093.1 - 0.06 12.4 1.9 0.087 11.9 1.9 1.2 1 0 0 1 1 1 0 TMEM192 family Meckelin PF09773.9 EGO24093.1 - 1.8 6.5 4.3 2.4 6.1 4.3 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Myb_DNA-bind_3 PF12776.7 EGO24095.1 - 0.00026 21.9 3.9 0.00041 21.3 3.9 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO24095.1 - 0.0044 17.4 1.7 0.006 16.9 1.3 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO24095.1 - 0.013 15.7 0.3 0.021 15.0 0.3 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EGO24095.1 - 0.016 15.2 1.9 0.021 14.9 0.9 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Protamine_3 PF08188.11 EGO24095.1 - 0.088 13.0 0.8 0.16 12.2 0.8 1.4 1 0 0 1 1 1 0 Spermatozal protamine family Retrotran_gag_2 PF14223.6 EGO24096.1 - 8.6e-13 48.1 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO24096.1 - 8.7e-05 22.1 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO24096.1 - 0.0022 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1771 PF08590.10 EGO24097.1 - 0.044 14.2 1.1 0.067 13.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_6 PF15288.6 EGO24097.1 - 0.051 13.4 0.9 0.91 9.4 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO24097.1 - 0.057 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO24097.1 - 0.095 12.5 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger DUF4718 PF15842.5 EGO24097.1 - 0.14 11.9 0.5 0.17 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) gag_pre-integrs PF13976.6 EGO24098.1 - 3.5e-11 42.8 0.3 4.9e-11 42.3 0.3 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain DDE_1 PF03184.19 EGO24099.1 - 4.4e-06 26.5 0.3 1.3e-05 24.9 0.1 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease SAP PF02037.27 EGO24099.1 - 0.016 14.9 0.7 0.052 13.3 0.0 2.1 2 0 0 2 2 2 0 SAP domain PIG-L PF02585.17 EGO24099.1 - 0.025 15.2 2.2 0.11 13.1 0.7 2.2 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase SSI PF00720.17 EGO24100.1 - 0.095 12.7 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Subtilisin inhibitor-like But2 PF09792.9 EGO24103.1 - 6.5e-08 33.1 0.0 9.4e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 EGO24104.1 - 1.6e-20 73.9 2.1 1.5e-18 67.4 0.7 2.9 1 1 0 2 2 2 2 Domain of unknown function (DUF3328) MAGI_u5 PF16666.5 EGO24106.1 - 1.6 8.9 6.7 0.7 10.0 4.5 1.5 2 0 0 2 2 2 0 Unstructured region on MAGI Q_salvage PF10343.9 EGO24107.1 - 5.8e-93 311.5 0.0 7.5e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family HHH_8 PF14716.6 EGO24108.1 - 1.1e-13 51.4 0.3 1e-10 41.8 0.1 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EGO24108.1 - 7.6e-11 41.7 0.0 2.7e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EGO24108.1 - 6.7e-06 26.6 0.1 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 EGO24108.1 - 4e-05 23.3 0.1 0.1 12.5 0.0 2.7 3 0 0 3 3 3 2 Helix-hairpin-helix motif Cdd1 PF11731.8 EGO24108.1 - 0.00035 20.7 0.0 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 Pathogenicity locus HHH_2 PF12826.7 EGO24108.1 - 0.0095 16.0 0.0 4.7 7.4 0.0 2.6 2 1 1 3 3 3 2 Helix-hairpin-helix motif Amidohydro_1 PF01979.20 EGO24108.1 - 0.044 13.1 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family HHH_3 PF12836.7 EGO24108.1 - 0.053 13.8 0.0 8.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif HRDC PF00570.23 EGO24108.1 - 0.074 13.0 0.0 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 HRDC domain Skp1 PF01466.19 EGO24108.1 - 0.2 11.8 1.9 0.92 9.7 0.0 2.9 4 0 0 4 4 4 0 Skp1 family, dimerisation domain SNF5 PF04855.12 EGO24109.1 - 1.9e-58 198.0 0.0 2.1e-57 194.7 0.0 1.9 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 LRRNT PF01462.18 EGO24109.1 - 0.023 14.3 0.1 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-H2C2_2 PF13465.6 EGO24110.1 - 0.024 15.0 1.1 0.055 13.9 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 EGO24110.1 - 0.032 14.7 0.2 0.063 13.8 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Gelsolin PF00626.22 EGO24112.1 - 1.5e-33 114.5 0.0 4.4e-17 61.8 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Vault_4 PF17796.1 EGO24112.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 Major Vault Protein repeat domain Methyltransf_33 PF10017.9 EGO24113.1 - 7.9e-74 248.6 0.0 3.6e-73 246.4 0.0 1.8 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EGO24113.1 - 1.4e-23 83.8 4.1 4.5e-13 49.4 0.2 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGO24113.1 - 1.9e-05 25.2 0.3 4.7e-05 23.9 0.3 1.7 1 0 0 1 1 1 1 DinB superfamily DHHC PF01529.20 EGO24115.1 - 8.3e-34 116.6 4.0 8.3e-34 116.6 4.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 EGO24115.1 - 1.1 9.2 5.6 2.5 8.1 5.6 1.5 1 0 0 1 1 1 0 Ribosomal L40e family DZR PF12773.7 EGO24115.1 - 3.9 7.6 7.9 6.3 6.9 7.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon Epimerase PF01370.21 EGO24116.1 - 5.1e-11 42.5 0.0 9.9e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO24116.1 - 6.6e-08 32.7 0.0 8.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO24116.1 - 0.00021 20.9 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EGO24116.1 - 0.00072 19.2 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.17 EGO24116.1 - 0.003 16.7 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGO24116.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EGO24116.1 - 0.071 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 EGO24116.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Asp PF00026.23 EGO24117.1 - 1.2e-46 159.6 17.3 5.4e-46 157.5 17.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO24117.1 - 2.4e-08 34.4 10.6 0.00027 21.2 0.3 3.8 1 1 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO24117.1 - 0.0035 18.0 5.6 0.33 11.6 1.3 2.6 2 0 0 2 2 2 2 Aspartyl protease BTB PF00651.31 EGO24118.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain APC1_C PF18122.1 EGO24118.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Amidohydro_1 PF01979.20 EGO24119.1 - 1.3e-64 218.8 0.0 1e-63 215.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO24119.1 - 1.2e-09 38.2 0.0 9.4e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EGO24119.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase PLDc_2 PF13091.6 EGO24121.1 - 7.3e-19 68.0 0.0 3e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGO24121.1 - 0.00013 22.0 1.0 0.069 13.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif SIR2 PF02146.17 EGO24122.1 - 1.2e-41 142.5 0.0 1.7e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family RVT_1 PF00078.27 EGO24122.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S28 PF05577.12 EGO24123.1 - 4.5e-54 183.9 0.0 1.1e-53 182.7 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 HEAT PF02985.22 EGO24125.1 - 3.7e-19 67.2 0.6 0.007 16.5 0.1 7.5 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 EGO24125.1 - 7.2e-08 32.7 0.0 0.1 13.0 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EGO24125.1 - 0.00046 20.3 10.6 0.0061 16.6 0.2 3.8 1 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Ribosomal_L26 PF16906.5 EGO24125.1 - 0.0045 17.4 0.8 8.5 6.9 0.0 3.6 3 1 0 3 3 3 2 Ribosomal proteins L26 eukaryotic, L24P archaeal BPL_N PF09825.9 EGO24125.1 - 0.23 10.5 1.1 0.38 9.8 0.6 1.6 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DUF2235 PF09994.9 EGO24126.1 - 0.034 13.5 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) YjeF_N PF03853.15 EGO24129.1 - 6.5e-40 136.8 0.0 8.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus zf-MYND PF01753.18 EGO24130.1 - 4.6e-11 42.6 2.1 1.4e-10 41.0 2.1 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EGO24130.1 - 0.00038 20.5 0.8 0.00085 19.4 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Fer4_11 PF13247.6 EGO24130.1 - 0.29 11.3 4.4 4.8 7.4 1.0 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain HEPN_RES_NTD1 PF18870.1 EGO24131.1 - 0.044 14.0 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 CRAL_TRIO PF00650.20 EGO24131.1 - 0.052 13.3 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain DDE_Tnp_4 PF13359.6 EGO24133.1 - 8.9e-30 103.5 0.0 1.3e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO24133.1 - 9.3e-08 32.0 0.0 3.6e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 EGO24133.1 - 0.00075 19.2 0.2 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DUF2235 PF09994.9 EGO24135.1 - 3.7e-63 213.6 0.2 1.4e-61 208.4 0.2 2.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Cullin PF00888.22 EGO24136.1 - 2.2e-20 72.8 0.5 4e-20 72.0 0.2 1.5 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 EGO24136.1 - 6.4e-17 61.8 0.3 2.4e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Peptidase_S9 PF00326.21 EGO24137.1 - 3e-13 49.7 0.1 8.6e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGO24137.1 - 7.6e-08 32.5 0.0 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 EGO24137.1 - 0.0023 17.5 0.0 0.69 9.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGO24137.1 - 0.0039 16.9 0.1 2.6 7.6 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO24137.1 - 0.0042 16.4 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGO24137.1 - 0.0052 16.4 0.4 0.12 11.9 0.3 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGO24137.1 - 0.0069 17.0 0.2 0.0099 16.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGO24137.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Patatin PF01734.22 EGO24137.1 - 0.081 13.1 0.3 0.22 11.7 0.3 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase Abhydrolase_4 PF08386.10 EGO24137.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 1 0 1 1 1 0 TAP-like protein Aldo_ket_red PF00248.21 EGO24138.1 - 4.6e-39 134.4 0.1 2.2e-32 112.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family BTB PF00651.31 EGO24139.1 - 0.00013 22.2 0.0 0.00033 20.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF1415 PF07209.12 EGO24139.1 - 0.1 12.3 0.2 0.33 10.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) Ribonuc_red_lgC PF02867.15 EGO24141.1 - 8e-183 608.7 0.0 1.1e-182 608.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGO24141.1 - 6.1e-24 83.8 0.0 1.5e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGO24141.1 - 3.7e-15 56.3 0.1 9.6e-15 54.9 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain TcpA PF05946.12 EGO24141.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA DUF3417 PF11897.8 EGO24141.1 - 0.16 12.4 0.2 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) Avl9 PF09794.9 EGO24143.1 - 4.2e-123 410.8 0.0 5.6e-123 410.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EGO24143.1 - 3.2e-08 33.5 0.9 0.013 15.1 0.3 2.9 2 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EGO24143.1 - 2.5e-07 30.7 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Orthopox_A5L PF06193.11 EGO24143.1 - 3.4 7.0 6.5 0.31 10.5 0.1 2.3 3 0 0 3 3 3 0 Orthopoxvirus A5L protein-like PTH2 PF01981.16 EGO24144.1 - 9.7e-47 158.1 0.3 1.3e-46 157.7 0.3 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Rsm22 PF09243.10 EGO24144.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.25 EGO24145.1 - 1.2e-67 228.0 0.0 1.8e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO24145.1 - 8.5e-36 123.6 0.0 3.5e-35 121.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGO24145.1 - 0.002 17.2 0.1 0.0038 16.3 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGO24145.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO24145.1 - 0.015 14.1 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EGO24145.1 - 0.15 11.6 0.3 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 EGO24145.1 - 0.17 10.8 0.1 0.34 9.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain AMPKBI PF04739.15 EGO24146.1 - 2.1e-21 76.0 2.4 3.9e-21 75.1 2.4 1.7 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain DUF1652 PF07865.11 EGO24148.1 - 0.051 13.4 0.6 0.33 10.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DUF4541 PF15074.6 EGO24151.1 - 0.062 13.9 0.4 0.15 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) DUF974 PF06159.13 EGO24151.1 - 0.075 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF974) A_deaminase PF00962.22 EGO24152.1 - 8.7e-122 406.5 0.1 1.1e-121 406.2 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Piwi PF02171.17 EGO24152.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Piwi domain DUF2235 PF09994.9 EGO24153.1 - 3.6e-84 282.5 0.1 4.7e-84 282.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FSH1 PF03959.13 EGO24153.1 - 0.041 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 EGO24153.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aldedh PF00171.22 EGO24154.1 - 1.1e-181 604.4 0.8 1.3e-181 604.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO24154.1 - 0.04 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) BHD_3 PF10405.9 EGO24155.1 - 9.5e-29 99.6 0.1 1.9e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EGO24155.1 - 2.3e-22 79.3 0.8 4.8e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EGO24155.1 - 3.9e-21 74.6 0.0 9e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGO24155.1 - 4.4e-18 66.0 1.6 4.4e-18 66.0 1.6 4.0 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EGO24155.1 - 9.7e-06 26.0 0.1 0.00014 22.2 0.1 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily GCD14 PF08704.10 EGO24156.1 - 2e-88 296.2 0.1 7.1e-87 291.2 0.1 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGO24156.1 - 0.00034 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGO24156.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NPR3 PF03666.13 EGO24156.1 - 0.13 11.0 0.5 0.2 10.4 0.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAS_3 PF08447.12 EGO24157.1 - 1.3e-07 31.8 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGO24157.1 - 3.4e-05 23.8 0.0 0.0001 22.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EGO24157.1 - 0.0066 16.7 0.0 0.043 14.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 EGO24157.1 - 0.011 15.8 0.0 0.032 14.4 0.0 1.6 2 0 0 2 2 2 0 PAS domain PAS_9 PF13426.7 EGO24157.1 - 0.012 15.8 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 PAS domain Melibiase_2 PF16499.5 EGO24158.1 - 9.6e-51 172.6 1.1 6.8e-27 94.4 0.9 2.4 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EGO24158.1 - 8.7e-12 44.9 0.5 2.6e-11 43.4 0.5 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGO24158.1 - 0.00098 18.2 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Melibiase Peptidase_M3 PF01432.20 EGO24162.1 - 1.2e-132 443.4 0.0 2.4e-132 442.5 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 EGO24162.1 - 0.045 13.4 0.2 0.078 12.6 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like CAP PF00188.26 EGO24163.1 - 1.3e-21 77.8 1.8 1.7e-21 77.4 1.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Bud13 PF09736.9 EGO24164.1 - 3.2e-56 189.8 10.3 3.2e-56 189.8 10.3 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex UvrD-helicase PF00580.21 EGO24167.1 - 2.4e-19 70.0 0.0 3.2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EGO24167.1 - 9.6e-13 48.2 0.0 1.4e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EGO24167.1 - 3.7e-09 37.1 0.0 5.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sugar_tr PF00083.24 EGO24168.1 - 1.5e-109 366.8 27.1 2e-109 366.5 27.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO24168.1 - 4.8e-28 98.1 46.6 1.2e-20 73.8 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EGO24169.1 - 1.3e-23 83.5 17.1 8.8e-15 54.5 9.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2 PF00152.20 EGO24170.1 - 1e-75 254.8 0.0 1.4e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO24170.1 - 3.6e-09 36.5 0.1 8.7e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO24170.1 - 0.0071 15.9 0.2 1.3 8.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) RNA_pol_Rpc4 PF05132.14 EGO24170.1 - 0.14 12.5 5.4 0.25 11.8 5.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_C14 PF00656.22 EGO24172.1 - 1.9e-34 119.8 0.0 3.3e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Metallophos PF00149.28 EGO24173.1 - 2.9e-09 37.7 0.3 5.9e-09 36.7 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO24173.1 - 3.1e-05 24.2 0.0 4.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGO24173.1 - 0.062 12.6 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily GGACT PF06094.12 EGO24174.1 - 2.8e-12 47.3 0.0 4.1e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aminotran_5 PF00266.19 EGO24175.1 - 3.4e-18 65.8 0.0 2.6e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGO24175.1 - 6e-08 32.2 0.0 1.3e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGO24175.1 - 2.4e-06 27.1 0.1 1.6e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CTU2 PF10288.9 EGO24176.1 - 2.9e-19 69.4 0.0 6.4e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 EGO24176.1 - 0.008 16.0 0.8 0.008 16.0 0.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Gin PF10764.9 EGO24176.1 - 0.54 10.2 5.1 2.1 8.4 0.6 2.9 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin Asp PF00026.23 EGO24177.1 - 2.8e-16 59.9 0.0 5.4e-11 42.5 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGO24177.1 - 3e-06 27.8 0.1 0.0093 16.6 0.1 3.9 3 2 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO24177.1 - 0.00016 22.2 0.1 0.063 13.9 0.0 3.8 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease CYYR1 PF10873.8 EGO24177.1 - 0.0037 17.7 0.0 0.0077 16.7 0.0 1.5 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 EGO24177.1 - 0.04 14.8 0.0 0.11 13.4 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 EGO24177.1 - 0.041 13.6 0.2 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SecE PF00584.20 EGO24177.1 - 0.11 12.4 0.5 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex EMP24_GP25L PF01105.24 EGO24177.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TMEM52 PF14979.6 EGO24177.1 - 0.2 11.6 0.9 0.43 10.5 0.9 1.5 1 0 0 1 1 1 0 Transmembrane 52 Adeno_E3_CR2 PF02439.15 EGO24177.1 - 0.27 11.0 5.1 0.52 10.1 5.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UPRTase PF14681.6 EGO24178.1 - 7.6e-49 166.0 0.0 8.4e-47 159.3 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRK PF00485.18 EGO24178.1 - 1.8e-42 145.3 1.7 5.1e-39 134.1 0.0 2.3 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGO24178.1 - 0.001 19.6 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EGO24178.1 - 0.036 13.8 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase Na_Ca_ex PF01699.24 EGO24179.1 - 5.8e-22 78.3 34.5 1.1e-13 51.4 13.6 3.4 2 1 1 3 3 3 3 Sodium/calcium exchanger protein COX5B PF01215.19 EGO24180.1 - 7e-45 151.9 0.0 8.4e-45 151.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EGO24180.1 - 0.038 14.0 0.3 0.056 13.5 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger domain zf-H2C2_2 PF13465.6 EGO24184.1 - 5.7e-07 29.7 0.1 5.7e-07 29.7 0.1 4.0 5 0 0 5 5 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO24184.1 - 0.00032 21.3 11.0 0.0077 17.0 1.9 3.1 4 0 0 4 4 2 2 C2H2-type zinc finger HalOD2 PF18547.1 EGO24184.1 - 0.0018 18.1 0.5 0.0036 17.2 0.5 1.5 1 0 0 1 1 1 1 Halobacterial output domain 2 zf-FCS PF06467.14 EGO24184.1 - 0.0028 17.6 5.9 0.96 9.4 2.0 2.5 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif LIM PF00412.22 EGO24184.1 - 0.0048 17.1 3.5 0.052 13.8 0.1 2.3 2 0 0 2 2 2 1 LIM domain zf-C2H2 PF00096.26 EGO24184.1 - 0.0091 16.4 3.0 0.0091 16.4 3.0 3.2 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-met PF12874.7 EGO24184.1 - 0.01 16.2 12.2 0.12 12.8 3.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BolA PF01722.18 EGO24184.1 - 0.034 14.4 0.1 0.91 9.8 0.1 2.3 1 1 0 1 1 1 0 BolA-like protein FYVE PF01363.21 EGO24184.1 - 0.042 14.0 5.3 0.1 12.8 5.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-CCHC_2 PF13696.6 EGO24184.1 - 0.048 13.5 1.4 1.7 8.5 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle C5HCH PF17982.1 EGO24184.1 - 0.083 13.1 4.2 1.2 9.4 2.4 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain Desulfoferrod_N PF06397.12 EGO24184.1 - 0.17 11.5 0.5 1 9.0 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_jaz PF12171.8 EGO24184.1 - 0.18 12.2 12.3 1.6 9.1 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGO24184.1 - 0.7 9.7 5.3 0.59 9.9 0.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 EGO24184.1 - 1.7 9.0 8.0 12 6.3 2.8 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 EGO24184.1 - 2.5 8.3 5.5 7.2 6.8 1.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 EGO24184.1 - 4.1 7.7 10.6 6.9 6.9 1.8 2.7 1 1 1 2 2 2 0 AN1-like Zinc finger Ephrin_rec_like PF07699.13 EGO24184.1 - 4.5 7.1 8.3 0.72 9.7 0.2 2.9 3 0 0 3 3 3 0 Putative ephrin-receptor like zf-LYAR PF08790.11 EGO24184.1 - 6.1 6.8 9.1 6.7 6.7 1.8 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Torus PF16131.5 EGO24187.1 - 2e-39 134.7 1.9 3.8e-39 133.8 1.9 1.5 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EGO24187.1 - 4.1e-06 26.5 0.0 9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO24187.1 - 0.004 17.1 0.1 0.0081 16.1 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EGO24187.1 - 0.14 12.2 5.4 0.28 11.3 5.4 1.5 1 0 0 1 1 1 0 Zinc finger domain DUF2415 PF10313.9 EGO24188.1 - 0.00073 19.4 0.1 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 EGO24188.1 - 0.021 13.8 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 EGO24188.1 - 0.033 15.1 3.4 2e+02 3.1 0.0 5.7 6 0 0 6 6 6 0 WD domain, G-beta repeat ABC_membrane PF00664.23 EGO24189.1 - 9.8e-41 140.2 8.7 1.2e-40 139.9 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGO24189.1 - 5.9e-34 117.5 0.0 1.2e-33 116.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGO24189.1 - 5.7e-06 25.9 0.5 0.003 17.0 0.0 2.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGO24189.1 - 0.0001 22.2 0.0 0.00059 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGO24189.1 - 0.0012 18.7 0.0 0.045 13.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGO24189.1 - 0.0035 17.7 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO24189.1 - 0.02 15.1 0.0 0.082 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGO24189.1 - 0.031 14.7 0.0 0.37 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGO24189.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 EGO24189.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO24189.1 - 0.054 14.0 0.1 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO24189.1 - 0.061 13.9 0.0 0.33 11.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain Rop-like PF05082.13 EGO24189.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Rop-like MMR_HSR1 PF01926.23 EGO24189.1 - 0.092 12.8 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO24189.1 - 0.12 12.3 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EGO24189.1 - 0.14 12.4 0.0 0.86 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGO24189.1 - 0.84 9.9 3.9 1.7 8.9 0.3 3.0 3 1 0 3 3 1 0 Putative exonuclease SbcCD, C subunit Ribonuc_red_sm PF00268.21 EGO24189.1 - 1.8 8.0 5.1 0.26 10.7 0.3 1.8 2 0 0 2 2 2 0 Ribonucleotide reductase, small chain LRR_4 PF12799.7 EGO24190.1 - 2.7e-22 78.5 27.4 8.6e-06 26.0 4.6 9.0 7 2 1 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO24190.1 - 8.8e-21 73.4 24.2 2.7e-10 39.8 5.9 8.9 7 2 3 10 10 10 7 Leucine rich repeat LRR_6 PF13516.6 EGO24190.1 - 1.4e-09 37.3 21.0 0.13 12.3 1.1 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 EGO24190.1 - 1.7e-06 27.8 21.6 4 8.4 0.1 9.6 10 1 0 10 10 10 3 Leucine Rich Repeat FliG_N PF14842.6 EGO24190.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain DFRP_C PF16543.5 EGO24191.1 - 5.6e-32 110.1 5.3 5.6e-32 110.1 5.3 3.3 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 EGO24191.1 - 1.1e-07 31.6 17.3 2.8e-05 24.0 5.7 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGO24191.1 - 6.3e-07 29.1 7.5 0.00078 19.2 1.2 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 EGO24191.1 - 4.5e-06 26.4 10.7 2.1e-05 24.3 1.0 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGO24191.1 - 6e-05 23.7 14.3 0.0013 19.4 1.0 3.6 2 2 2 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 EGO24191.1 - 0.0012 19.0 0.9 0.4 10.9 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGO24191.1 - 0.0013 19.1 8.6 0.18 12.3 2.8 2.7 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger PS_Dcarbxylase PF02666.15 EGO24192.1 - 2.4e-58 197.0 0.0 3.9e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EGO24192.1 - 1.1e-34 118.8 0.0 8.1e-20 71.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain HMG_box PF00505.19 EGO24194.1 - 0.00012 22.4 1.7 0.00024 21.4 1.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO24194.1 - 0.00021 21.8 2.0 0.0005 20.6 2.0 1.7 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 EGO24194.1 - 0.043 14.4 0.9 0.043 14.4 0.9 1.8 1 1 1 2 2 2 0 YABBY protein DUF4449 PF14613.6 EGO24195.1 - 2.5e-15 57.0 1.8 6.3e-14 52.4 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) LMBR1 PF04791.16 EGO24195.1 - 0.077 11.9 0.4 0.11 11.4 0.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HemY_N PF07219.13 EGO24195.1 - 0.084 13.1 0.3 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 HemY protein N-terminus TED PF08341.11 EGO24195.1 - 0.096 13.1 0.2 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 Thioester domain Mito_carr PF00153.27 EGO24196.1 - 3.2e-56 187.3 1.9 3.3e-20 71.8 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO24196.1 - 0.00016 20.9 0.0 0.061 12.5 0.0 2.6 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF2085 PF09858.9 EGO24196.1 - 0.13 12.7 0.3 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Sec_GG PF07549.14 EGO24198.1 - 0.066 12.7 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Calpain_u2 PF16648.5 EGO24202.1 - 0.097 13.2 0.5 0.097 13.2 0.5 2.1 2 0 0 2 2 2 0 Unstructured region on Calpain-3 DUF1848 PF08902.11 EGO24203.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Plavaka PF18759.1 EGO24204.1 - 1.7e-21 76.8 0.1 1.7e-21 76.8 0.1 1.5 2 0 0 2 2 2 1 Plavaka transposase Smg4_UPF3 PF03467.15 EGO24204.1 - 0.028 14.4 4.4 0.047 13.7 4.4 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family XRN1_D1 PF18332.1 EGO24206.1 - 8.7e-60 201.8 0.0 1e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain PrpF PF04303.13 EGO24207.1 - 2.1e-77 260.6 0.0 2.4e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 PrpF protein CDC27 PF09507.10 EGO24208.1 - 1.2e-12 48.0 10.2 1.7e-12 47.5 10.2 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 EGO24208.1 - 0.01 16.2 4.0 0.01 16.2 4.0 2.5 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4727 PF15856.5 EGO24210.1 - 0.0022 17.6 2.1 0.6 9.7 0.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4727) GMP_synt_C PF00958.22 EGO24211.1 - 7.8e-45 150.9 0.1 1.4e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EGO24211.1 - 1.3e-33 116.3 0.0 2.3e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EGO24211.1 - 5.7e-10 38.7 0.2 3.8e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGO24211.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EGO24211.1 - 0.0031 16.4 0.1 0.0052 15.6 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EGO24211.1 - 0.0048 16.5 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EGO24211.1 - 0.014 14.9 1.0 0.022 14.3 0.0 1.9 2 1 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 EGO24211.1 - 0.043 13.1 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 EGO24211.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family YbhQ PF11076.8 EGO24212.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ FixH PF05751.11 EGO24212.1 - 0.21 11.6 0.1 0.4 10.7 0.0 1.5 2 0 0 2 2 2 0 FixH TPPK_C PF12555.8 EGO24212.1 - 1.8 8.7 4.2 3.8 7.6 4.2 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal His_biosynth PF00977.21 EGO24213.1 - 6.9e-42 143.5 0.7 4.4e-41 140.8 0.7 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EGO24213.1 - 2e-22 79.9 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGO24213.1 - 1.2e-07 31.5 0.0 3.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EGO24213.1 - 1.6e-06 28.1 0.0 6.7e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 SNO glutamine amidotransferase family Peptidase_S51 PF03575.17 EGO24213.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_C26 PF07722.13 EGO24213.1 - 0.013 15.3 0.2 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 MFS_1 PF07690.16 EGO24214.1 - 9.5e-26 90.5 24.8 9.5e-26 90.5 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IBN_N PF03810.19 EGO24216.1 - 0.013 15.4 0.6 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain Alpha_kinase PF02816.18 EGO24216.1 - 0.088 12.9 0.2 0.22 11.6 0.2 1.8 1 1 0 1 1 1 0 Alpha-kinase family GHMP_kinases_N PF00288.26 EGO24216.1 - 0.14 12.5 2.2 4.9 7.5 0.8 2.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain FAST_1 PF06743.15 EGO24216.1 - 0.38 10.7 3.6 1.2 9.1 0.8 2.4 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 1 MFS_1 PF07690.16 EGO24217.1 - 1.9e-25 89.5 25.0 1.9e-25 89.5 25.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 EGO24218.1 - 0.063 13.2 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGO24218.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like TFIIF_beta PF02270.15 EGO24219.1 - 4.7e-26 90.7 0.1 7.2e-26 90.1 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EGO24219.1 - 6.8e-19 68.9 0.0 1.5e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus GCIP PF13324.6 EGO24219.1 - 0.29 10.7 1.3 0.41 10.2 1.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EGO24219.1 - 3.1 8.3 10.6 7.7 7.0 10.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fungal_trans PF04082.18 EGO24220.1 - 6.2e-32 110.7 0.1 1e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 EGO24220.1 - 0.0076 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain NACHT PF05729.12 EGO24221.1 - 2.7e-09 37.2 0.2 1.7e-08 34.5 0.2 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO24221.1 - 8.7e-07 29.5 0.1 1.6e-06 28.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EGO24221.1 - 6.5e-05 22.3 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EGO24221.1 - 7.4e-05 23.2 0.0 0.00021 21.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO24221.1 - 0.00068 19.9 0.0 0.0032 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EGO24221.1 - 0.0007 19.5 0.0 0.0055 16.6 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase RNA_helicase PF00910.22 EGO24221.1 - 0.0019 18.6 0.0 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 EGO24221.1 - 0.0032 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 EGO24221.1 - 0.0074 16.0 0.2 0.078 12.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGO24221.1 - 0.012 15.5 0.0 0.047 13.6 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGO24221.1 - 0.013 15.1 0.2 0.045 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGO24221.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 EGO24221.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 3HCDH_RFF PF18321.1 EGO24221.1 - 0.036 14.5 1.6 5.4 7.5 0.2 3.0 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain NTPase_1 PF03266.15 EGO24221.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 EGO24221.1 - 0.087 12.0 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 EGO24221.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EGO24221.1 - 0.15 12.4 0.0 0.78 10.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO24221.1 - 0.19 12.3 0.0 0.34 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 EGO24222.1 - 3.8e-09 37.0 0.7 2.7e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 EGO24223.1 - 3.8e-22 78.2 15.3 3.7e-10 40.2 0.3 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO24223.1 - 1.1e-08 35.3 0.0 0.051 13.9 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO24223.1 - 2.4e-06 26.7 0.8 0.17 10.8 0.0 3.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO24223.1 - 9e-05 22.3 0.8 3.3 7.8 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EGO24223.1 - 0.0016 18.2 0.6 0.38 10.5 0.0 2.9 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 EGO24223.1 - 0.014 14.1 0.0 1.2 7.7 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Big_7 PF17957.1 EGO24223.1 - 0.031 15.0 1.2 1.6 9.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial Ig domain Inositol_P PF00459.25 EGO24223.1 - 0.13 11.7 0.1 6.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Inositol monophosphatase family DUF5570 PF17731.1 EGO24223.1 - 0.15 12.2 6.2 1.8 8.7 0.2 3.2 2 2 1 3 3 3 0 Family of unknown function (DUF5570) Proteasome_A_N PF10584.9 EGO24223.1 - 0.18 11.5 5.3 8.4 6.2 0.2 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3295 PF11702.8 EGO24228.1 - 3.4e-13 49.8 10.8 3.5e-13 49.8 10.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) Fungal_trans PF04082.18 EGO24230.1 - 1.3e-30 106.3 0.0 2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO24230.1 - 0.0094 16.1 0.5 0.018 15.2 0.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EGO24232.1 - 4e-33 112.9 14.6 1.2e-11 44.9 0.2 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO24232.1 - 6.1e-10 39.3 0.0 0.0064 16.8 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EGO24232.1 - 5.2e-08 33.0 0.1 2.6e-07 30.7 0.1 2.1 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EGO24232.1 - 3.4e-07 29.6 2.7 0.0093 15.0 0.0 3.4 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EGO24232.1 - 3.5e-07 30.8 0.1 9.7e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EGO24232.1 - 0.00012 22.5 0.0 0.00044 20.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGO24232.1 - 0.0012 18.2 0.0 0.023 13.9 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGO24232.1 - 0.0016 18.7 0.0 0.0052 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EGO24232.1 - 0.0033 17.3 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase PD40 PF07676.12 EGO24232.1 - 0.0097 15.8 0.1 8.8 6.4 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGO24232.1 - 0.013 15.4 0.0 1.9 8.3 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Zeta_toxin PF06414.12 EGO24232.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EGO24232.1 - 0.03 14.7 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 EGO24232.1 - 0.082 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SEEK1 PF15357.6 EGO24232.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 ATPase_2 PF01637.18 EGO24232.1 - 0.14 12.1 0.0 0.42 10.5 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGO24232.1 - 0.14 11.9 0.1 0.59 9.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGO24232.1 - 0.18 11.4 0.1 0.67 9.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain GalKase_gal_bdg PF10509.9 EGO24233.1 - 1.2e-07 31.1 0.0 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Galactokinase galactose-binding signature WD40 PF00400.32 EGO24234.1 - 4.3e-94 305.8 45.2 8.7e-11 42.2 1.3 14.2 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO24234.1 - 2e-33 114.6 1.1 0.00096 19.4 0.0 11.0 3 3 8 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO24234.1 - 8.4e-20 71.0 15.0 0.11 11.4 0.0 11.0 4 3 7 11 11 11 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO24234.1 - 6.5e-18 64.2 5.7 1.5 8.9 0.0 11.7 12 0 0 12 12 12 3 WD40-like Beta Propeller Repeat NACHT PF05729.12 EGO24234.1 - 9.7e-10 38.6 0.1 3.9e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO24234.1 - 4.8e-07 30.3 0.4 2.1e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain Frtz PF11768.8 EGO24234.1 - 0.00033 19.1 0.0 0.098 11.0 0.0 4.0 5 0 0 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz AAA_22 PF13401.6 EGO24234.1 - 0.002 18.4 0.0 0.01 16.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.9 EGO24234.1 - 0.0051 16.1 0.0 0.08 12.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EGO24234.1 - 0.0065 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nup160 PF11715.8 EGO24234.1 - 0.0087 14.7 7.3 20 3.7 0.0 6.5 5 1 1 8 8 8 0 Nucleoporin Nup120/160 APS_kinase PF01583.20 EGO24234.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 EGO24234.1 - 0.03 14.7 0.0 0.26 11.7 0.0 2.7 3 0 0 3 3 1 0 RNA helicase Robl_LC7 PF03259.17 EGO24234.1 - 0.032 14.0 0.0 37 4.2 0.0 4.4 5 0 0 5 5 5 0 Roadblock/LC7 domain WD40_like PF17005.5 EGO24234.1 - 0.033 13.5 0.0 13 5.0 0.0 4.1 4 1 1 5 5 5 0 WD40-like domain Zeta_toxin PF06414.12 EGO24234.1 - 0.051 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MinC_C PF03775.16 EGO24234.1 - 0.11 12.5 0.0 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Septum formation inhibitor MinC, C-terminal domain AAA_25 PF13481.6 EGO24234.1 - 0.12 11.9 0.3 1 8.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EGO24234.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fibrinogen_aC PF12160.8 EGO24234.1 - 0.13 12.1 2.8 1.4 8.9 0.1 4.0 4 0 0 4 4 4 0 Fibrinogen alpha C domain KAP_NTPase PF07693.14 EGO24234.1 - 0.19 10.9 0.1 0.57 9.4 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain Rad17 PF03215.15 EGO24234.1 - 0.2 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4596 PF15363.6 EGO24234.1 - 8.6 6.7 12.2 21 5.4 0.1 5.6 5 0 0 5 5 4 0 Domain of unknown function (DUF4596) GalKase_gal_bdg PF10509.9 EGO24235.1 - 4.5e-21 74.1 0.1 8.7e-21 73.2 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGO24235.1 - 3.8e-15 56.0 0.0 9.8e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGO24235.1 - 6e-13 48.8 1.9 1.7e-12 47.4 1.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aldose_epim PF01263.20 EGO24236.1 - 4.4e-16 59.1 0.0 1.5e-14 54.0 0.0 2.7 1 1 0 1 1 1 1 Aldose 1-epimerase S10_plectin PF03501.15 EGO24238.1 - 4.2e-45 151.7 0.4 5e-45 151.5 0.4 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EGO24238.1 - 0.0078 16.1 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Kinase-like PF14531.6 EGO24238.1 - 0.19 11.0 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ADH_zinc_N PF00107.26 EGO24239.1 - 1.6e-11 44.3 0.0 3.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO24239.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.21 EGO24239.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit PPI_Ypi1 PF07491.11 EGO24240.1 - 4.5e-26 90.4 4.7 9.2e-26 89.5 4.7 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 EGO24240.1 - 0.06 11.9 1.9 0.074 11.6 1.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-MYND PF01753.18 EGO24241.1 - 4.7e-10 39.4 9.3 1.1e-09 38.2 9.3 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO24241.1 - 0.0093 16.3 6.5 0.019 15.2 6.5 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf_C2H2_13 PF18508.1 EGO24241.1 - 0.1 12.2 3.8 0.35 10.5 0.7 2.5 1 1 1 2 2 2 0 Zinc finger domain IDO PF01231.18 EGO24243.1 - 2.2e-125 418.9 0.0 2.5e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AAA PF00004.29 EGO24244.1 - 2.8e-15 56.9 0.0 6.1e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO24244.1 - 1.4e-10 41.9 0.0 6.3e-10 39.7 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain BAH PF01426.18 EGO24244.1 - 6.6e-08 32.5 0.0 1.8e-07 31.0 0.0 1.8 2 0 0 2 2 1 1 BAH domain AAA_22 PF13401.6 EGO24244.1 - 1.2e-06 28.9 0.0 3.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 EGO24244.1 - 2.3e-06 27.6 0.1 5.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 EGO24244.1 - 4.1e-05 23.0 0.0 9.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGO24244.1 - 0.00055 20.3 0.1 0.0016 18.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 EGO24244.1 - 0.0097 15.8 0.0 0.043 13.7 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EGO24244.1 - 0.019 14.8 0.1 0.019 14.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO24244.1 - 0.024 14.5 0.0 0.14 12.1 0.0 2.3 2 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGO24244.1 - 0.075 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO24244.1 - 0.093 11.9 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EGO24244.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 EGO24244.1 - 0.13 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 EGO24244.1 - 0.14 12.6 0.0 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Oxidored_molyb PF00174.19 EGO24245.1 - 3.7e-57 192.7 0.1 9.5e-57 191.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGO24245.1 - 4.6e-53 178.9 0.2 8e-53 178.1 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EGO24245.1 - 8.6e-27 93.4 0.0 1.5e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGO24245.1 - 4.6e-26 91.6 0.0 1.3e-25 90.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EGO24245.1 - 1.1e-17 64.0 0.0 5.7e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EGO24245.1 - 0.00015 21.9 0.1 0.015 15.4 0.0 3.1 2 1 0 3 3 3 1 Ferric reductase NAD binding domain MFS_1 PF07690.16 EGO24246.1 - 3.9e-39 134.6 16.5 3.9e-39 134.6 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EGO24246.1 - 0.047 12.5 8.2 0.18 10.5 0.4 3.0 2 1 1 3 3 3 0 LacY proton/sugar symporter Ribosomal_L4 PF00573.22 EGO24247.1 - 1.8e-39 135.4 1.3 1.8e-39 135.4 1.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGO24247.1 - 7.1e-29 99.7 3.9 7.1e-29 99.7 3.9 2.5 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain E1_DerP2_DerF2 PF02221.15 EGO24248.1 - 1.1e-24 87.4 0.1 1.3e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 ML domain Cytochrom_C PF00034.21 EGO24250.1 - 9.3e-09 36.3 0.0 1.3e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGO24250.1 - 1e-08 35.3 0.6 1.2e-07 32.0 0.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGO24250.1 - 0.00018 21.2 0.8 0.0017 18.0 0.8 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome_C554 PF13435.6 EGO24250.1 - 0.032 15.1 0.0 0.06 14.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c554 and c-prime DUF3365 PF11845.8 EGO24250.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Pyr_redox_2 PF07992.14 EGO24251.1 - 6.9e-40 137.1 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EGO24251.1 - 2.9e-21 75.3 0.0 1.5e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR PF01077.22 EGO24251.1 - 1.4e-16 60.4 0.1 3.6e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 EGO24251.1 - 1.3e-15 57.5 7.6 5.7e-13 49.0 0.8 3.3 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 EGO24251.1 - 8.6e-15 55.1 0.3 2.4e-14 53.6 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGO24251.1 - 3.3e-11 43.0 0.3 2.1e-10 40.4 0.0 2.4 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EGO24251.1 - 7.6e-11 41.7 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EGO24251.1 - 6.8e-05 22.7 0.2 0.21 11.5 0.0 2.7 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EGO24251.1 - 0.00056 19.9 0.4 0.44 10.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EGO24251.1 - 0.015 14.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EGO24251.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EGO24251.1 - 0.04 12.6 0.1 0.75 8.4 0.0 2.7 3 1 1 4 4 4 0 HI0933-like protein DAO PF01266.24 EGO24251.1 - 0.082 12.5 0.0 18 4.8 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO24251.1 - 0.34 9.9 2.9 5.2 6.0 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 EGO24251.1 - 0.47 9.5 1.7 29 3.6 0.2 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A PARP PF00644.20 EGO24252.1 - 7.3e-13 48.6 2.6 9.8e-10 38.3 2.6 3.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Paired_CXXCH_1 PF09699.10 EGO24252.1 - 0.048 13.4 5.1 3.4 7.5 0.2 3.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 EGO24252.1 - 0.18 11.8 9.4 4.3 7.4 9.4 2.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c IATP PF04568.12 EGO24252.1 - 3.1 8.3 7.1 0.23 11.9 0.5 2.4 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP RPAP2_Rtr1 PF04181.13 EGO24252.1 - 3.1 8.2 12.8 0.98 9.8 0.3 3.8 4 0 0 4 4 4 0 Rtr1/RPAP2 family PDE6_gamma PF04868.12 EGO24252.1 - 4.2 7.7 6.6 3.8 7.8 0.2 2.8 2 1 1 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit Cytochrom_c3_2 PF14537.6 EGO24252.1 - 6.4 7.3 9.9 31 5.1 2.0 2.7 1 1 1 2 2 2 0 Cytochrome c3 Coq4 PF05019.13 EGO24254.1 - 2.6e-99 331.0 0.0 3e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Gemini_AL1_M PF08283.11 EGO24257.1 - 3.2e-35 120.5 1.1 7.4e-35 119.3 1.1 1.7 1 0 0 1 1 1 1 Geminivirus rep protein central domain Gemini_AL1 PF00799.20 EGO24257.1 - 1e-11 45.2 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain AAA_18 PF13238.6 EGO24257.1 - 0.084 13.4 0.0 0.31 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 EGO24257.1 - 0.086 11.7 0.0 0.76 8.5 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase TniB PF05621.11 EGO24257.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Ubiquitin_4 PF18036.1 EGO24258.1 - 0.00043 20.3 0.3 0.4 10.7 0.0 2.5 3 0 0 3 3 3 2 Ubiquitin-like domain ubiquitin PF00240.23 EGO24258.1 - 0.0019 17.9 0.8 0.41 10.4 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family DUF2316 PF10078.9 EGO24258.1 - 0.0097 16.1 0.2 6.4 7.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2316) GP17 PF17420.2 EGO24258.1 - 0.021 14.9 0.1 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 UN_NPL4 PF11543.8 EGO24258.1 - 0.084 13.4 0.7 4.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 3H PF02829.14 EGO24258.1 - 0.088 13.1 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 3H domain UPF0179 PF03684.13 EGO24258.1 - 0.14 12.1 0.0 7 6.5 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0179) Cpn60_TCP1 PF00118.24 EGO24259.1 - 1.7e-155 518.4 1.8 1.9e-155 518.2 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 EGO24260.1 - 3.9e-36 125.5 0.6 5.4e-36 125.0 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO24260.1 - 0.00073 19.9 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EGO24260.1 - 0.014 15.1 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sad1_UNC PF07738.13 EGO24261.1 - 1.9e-23 82.9 0.0 8.3e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF4618 PF15397.6 EGO24261.1 - 0.12 11.8 3.2 0.23 10.9 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Abhydrolase_1 PF00561.20 EGO24262.1 - 1.1e-33 116.9 0.0 1.6e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO24262.1 - 2.9e-11 43.1 0.0 1e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO24262.1 - 2.3e-08 34.9 0.0 3.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EGO24262.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 EGO24262.1 - 0.17 10.6 0.0 0.28 9.8 0.0 1.3 1 1 0 1 1 1 0 Ndr family CRAL_TRIO PF00650.20 EGO24263.1 - 6.2e-30 104.0 0.0 8.5e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO24263.1 - 3.5e-20 71.9 0.2 3.5e-20 71.9 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain UBA_4 PF14555.6 EGO24263.1 - 0.026 14.3 0.2 0.37 10.6 0.0 2.7 3 0 0 3 3 3 0 UBA-like domain ADH_N PF08240.12 EGO24264.1 - 1.5e-23 82.7 2.5 2.7e-23 81.9 2.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO24264.1 - 2.9e-13 49.9 0.0 5.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO24264.1 - 9.9e-05 21.8 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGO24264.1 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EGO24264.1 - 0.072 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGO24264.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGO24264.1 - 0.17 12.4 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N PF08240.12 EGO24265.1 - 1.3e-22 79.8 0.5 2.3e-22 78.9 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO24265.1 - 7.4e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO24265.1 - 2.3e-05 23.8 0.0 3.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EGO24265.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGO24265.1 - 0.0056 16.6 0.1 0.0093 15.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGO24265.1 - 0.011 15.9 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2695 PF10905.8 EGO24266.1 - 0.0027 17.9 0.5 0.009 16.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2695) Lebercilin PF15619.6 EGO24266.1 - 0.0048 16.6 0.3 0.0082 15.8 0.2 1.5 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF4446 PF14584.6 EGO24266.1 - 0.073 13.0 0.4 0.095 12.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Galactosyl_T PF01762.21 EGO24267.1 - 3.6e-10 40.0 0.0 7.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase ADH_N PF08240.12 EGO24268.1 - 4.1e-22 78.1 0.6 7.1e-22 77.3 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO24268.1 - 1.8e-14 53.8 0.0 3.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO24268.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGO24268.1 - 0.0063 16.7 0.0 0.0099 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EGO24268.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGO24268.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thaumatin PF00314.17 EGO24269.1 - 1.7e-69 233.7 20.8 2e-69 233.5 20.8 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EGO24269.1 - 0.0052 16.1 1.0 0.021 14.1 0.2 2.2 1 1 0 1 1 1 1 Beta-1,3-glucanase Thaumatin PF00314.17 EGO24270.1 - 1.7e-69 233.7 20.8 2e-69 233.5 20.8 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EGO24270.1 - 0.0052 16.1 1.0 0.021 14.1 0.2 2.2 1 1 0 1 1 1 1 Beta-1,3-glucanase Oxidored_molyb PF00174.19 EGO24271.1 - 4e-48 163.3 0.0 6.1e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGO24271.1 - 1e-09 38.6 1.3 8.1e-09 35.6 0.2 2.4 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EGO24274.1 - 1e-56 191.3 0.0 1.5e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGO24274.1 - 9.8e-13 48.3 1.6 6.3e-09 36.0 0.7 2.7 2 1 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain NUFIP1 PF10453.9 EGO24278.1 - 1.1e-16 60.4 0.1 2.2e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Sina PF03145.16 EGO24278.1 - 0.018 15.0 0.6 0.028 14.4 0.6 1.2 1 0 0 1 1 1 0 Seven in absentia protein family Peptidase_M16_C PF05193.21 EGO24279.1 - 1.8e-15 57.5 0.0 4.2e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGO24279.1 - 7e-11 42.3 0.1 2.3e-09 37.4 0.0 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EGO24279.1 - 0.00046 19.4 3.0 0.52 9.4 0.0 2.5 3 0 0 3 3 3 2 Peptidase M16C associated BAR_3 PF16746.5 EGO24280.1 - 0.0004 20.2 2.5 0.00069 19.4 2.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family Rubrerythrin PF02915.17 EGO24280.1 - 0.062 13.7 2.0 0.15 12.4 1.7 1.7 1 1 0 1 1 1 0 Rubrerythrin SKA1 PF07160.12 EGO24282.1 - 0.016 15.1 4.9 0.022 14.6 3.5 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 YscO PF07321.12 EGO24282.1 - 0.038 13.9 1.7 0.094 12.7 1.7 1.7 1 0 0 1 1 1 0 Type III secretion protein YscO ATG16 PF08614.11 EGO24282.1 - 0.043 14.0 0.1 0.043 14.0 0.1 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD PF14073.6 EGO24282.1 - 0.15 12.0 5.7 0.15 12.1 4.5 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Peptidase_M15_4 PF13539.6 EGO24282.1 - 0.17 12.4 0.1 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Dabb PF07876.12 EGO24283.1 - 1.9e-19 70.0 0.1 2.2e-19 69.9 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF126 PF01989.16 EGO24284.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 1 1 2 2 2 0 Aconitase X swivel domain XLF PF09302.11 EGO24286.1 - 1.8e-06 28.3 1.4 5.5e-06 26.7 1.3 1.8 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component SOG2 PF10428.9 EGO24286.1 - 8.4 5.5 12.0 11 5.1 12.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein G-patch PF01585.23 EGO24287.1 - 2.8e-10 39.9 0.1 5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 EGO24287.1 - 1.2e-09 38.3 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 EGO24287.1 - 0.027 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 G-patch domain Yop-YscD_cpl PF16697.5 EGO24287.1 - 0.045 14.1 0.0 0.29 11.5 0.0 2.1 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RF-1 PF00472.20 EGO24287.1 - 0.048 13.6 0.8 0.064 13.2 0.1 1.6 2 0 0 2 2 2 0 RF-1 domain Cyclin_N PF00134.23 EGO24289.1 - 6.1e-43 145.6 0.1 1.8e-42 144.1 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO24289.1 - 6e-27 94.1 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain BRI3BP PF14965.6 EGO24289.1 - 0.032 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 adh_short PF00106.25 EGO24290.1 - 2.7e-87 291.3 19.6 9.4e-45 152.5 4.9 3.2 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO24290.1 - 2.1e-65 220.6 16.6 1.2e-33 116.6 3.5 2.9 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EGO24290.1 - 2.5e-31 107.8 0.0 4.9e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EGO24290.1 - 2.2e-28 99.4 11.4 9.3e-16 58.2 2.9 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EGO24290.1 - 0.00062 19.9 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 EGO24290.1 - 0.00064 19.1 0.5 0.079 12.3 0.2 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGO24290.1 - 0.019 14.9 1.4 0.019 14.9 1.4 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 EGO24290.1 - 0.65 9.8 6.4 9.8 6.0 0.4 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Ldh_1_N PF00056.23 EGO24290.1 - 0.87 9.7 5.7 2.3 8.3 0.8 2.4 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF543 PF04418.12 EGO24290.1 - 6.9 6.7 9.2 12 5.9 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Na_Ca_ex PF01699.24 EGO24291.1 - 8.8e-14 51.7 15.5 8.8e-14 51.7 15.5 2.3 2 2 0 2 2 2 1 Sodium/calcium exchanger protein Glycos_transf_4 PF00953.21 EGO24291.1 - 0.00016 21.7 1.8 0.0071 16.3 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 4 m04gp34like PF12216.8 EGO24291.1 - 0.22 11.1 1.3 0.25 10.9 0.1 1.6 2 0 0 2 2 2 0 Immune evasion protein ParD_like PF11903.8 EGO24293.1 - 0.064 13.3 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system LRR_4 PF12799.7 EGO24294.1 - 0.00022 21.6 1.8 0.44 11.0 0.0 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGO24294.1 - 0.0007 19.4 0.1 0.0024 17.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like Erg28 PF03694.13 EGO24295.1 - 9.1e-43 145.1 6.0 1.1e-42 144.8 6.0 1.1 1 0 0 1 1 1 1 Erg28 like protein CS PF04969.16 EGO24297.1 - 0.00017 22.5 0.0 0.00039 21.4 0.0 1.6 1 0 0 1 1 1 1 CS domain DUF4685 PF15737.5 EGO24297.1 - 0.33 11.4 3.1 3.4 8.1 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4685) DUF2284 PF10050.9 EGO24299.1 - 0.061 13.1 1.2 0.22 11.3 1.0 2.0 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) DASH_Spc34 PF08657.10 EGO24299.1 - 0.1 12.4 3.7 0.24 11.2 2.0 2.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 ApoO PF09769.9 EGO24299.1 - 0.15 12.0 2.5 4.8 7.2 0.1 3.7 4 0 0 4 4 4 0 Apolipoprotein O DMPK_coil PF08826.10 EGO24299.1 - 0.19 11.8 18.3 0.91 9.7 0.1 5.1 4 0 0 4 4 4 0 DMPK coiled coil domain like DUF4140 PF13600.6 EGO24299.1 - 0.3 11.5 23.4 2.6 8.5 0.1 6.6 5 2 1 6 6 6 0 N-terminal domain of unknown function (DUF4140) DUF4988 PF16378.5 EGO24299.1 - 0.52 10.0 2.0 1.4 8.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function LPP PF04728.13 EGO24299.1 - 1.2 9.6 9.0 1.9 9.0 0.1 4.6 4 0 0 4 4 4 0 Lipoprotein leucine-zipper CorA PF01544.18 EGO24299.1 - 2.8 7.2 8.9 0.9 8.8 0.1 3.2 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein TPK_catalytic PF04263.16 EGO24301.1 - 3.5e-35 120.6 0.0 5.1e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGO24301.1 - 6e-21 73.9 0.3 1.2e-20 73.0 0.3 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain ThiS PF02597.20 EGO24302.1 - 4.5e-05 24.0 0.0 6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family Lactamase_B PF00753.27 EGO24303.1 - 3.9e-06 27.0 0.0 4.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4078 PF13300.6 EGO24304.1 - 7e-20 71.1 2.0 7e-20 71.1 2.0 3.1 2 1 0 3 3 3 1 Domain of unknown function (DUF4078) DDHD PF02862.17 EGO24304.1 - 0.098 12.8 1.6 0.17 12.0 1.6 1.4 1 0 0 1 1 1 0 DDHD domain LRR_4 PF12799.7 EGO24305.1 - 1.2e-33 114.5 43.5 4.8e-09 36.4 0.2 7.2 3 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO24305.1 - 1.9e-28 98.0 47.8 8.4e-11 41.5 5.4 6.3 4 1 3 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 EGO24305.1 - 5.9e-26 91.0 12.5 5.4e-10 39.0 0.1 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EGO24305.1 - 1.6e-07 30.8 20.1 2.6 8.3 0.4 8.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 EGO24305.1 - 5.5e-06 26.2 26.3 36 5.5 0.1 10.1 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_5 PF13306.6 EGO24305.1 - 0.047 13.7 0.1 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 EGO24305.1 - 0.068 13.9 0.4 9.7 7.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_12 PF18837.1 EGO24305.1 - 1.4 8.6 7.4 5.2 6.8 0.1 4.2 5 0 0 5 5 5 0 Leucine-rich repeat PAS_3 PF08447.12 EGO24306.1 - 0.003 17.8 0.0 0.0036 17.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGO24306.1 - 0.061 13.6 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 EGO24306.1 - 0.094 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 PAS fold Ank_5 PF13857.6 EGO24307.1 - 1.2e-13 51.0 0.1 2e-11 43.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO24307.1 - 6.1e-13 49.0 0.0 6.5e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO24307.1 - 1.1e-08 35.5 0.0 2.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO24307.1 - 1.1e-07 31.9 0.3 5.4e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGO24307.1 - 7.4e-07 29.0 0.0 2.4e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeat PRMT5 PF05185.16 EGO24309.1 - 8.2e-65 217.9 0.0 1.8e-64 216.7 0.0 1.6 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGO24309.1 - 1.1e-57 194.7 0.0 1.5e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 EGO24309.1 - 4.2e-37 127.7 0.0 5.9e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Met_10 PF02475.16 EGO24309.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Phage_Coat_A PF05357.13 EGO24309.1 - 0.19 11.5 0.5 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Phage Coat Protein A AbrB-like PF14250.6 EGO24310.1 - 0.042 13.9 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Na_Ca_ex PF01699.24 EGO24311.1 - 4.8e-45 153.2 49.5 1.5e-29 102.9 13.8 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein SGL PF08450.12 EGO24312.1 - 0.029 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF1736 PF08409.11 EGO24312.1 - 0.089 12.8 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) Lactonase PF10282.9 EGO24312.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PFK PF00365.20 EGO24314.1 - 2.5e-185 614.4 0.0 1.1e-101 339.9 0.0 2.9 2 1 0 2 2 2 2 Phosphofructokinase DUF1295 PF06966.12 EGO24315.1 - 3.6e-44 151.0 0.0 5e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EGO24315.1 - 2.2e-06 28.0 0.1 8.7e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EGO24315.1 - 0.0048 15.7 0.0 0.0098 14.7 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 EGO24315.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 Phospholipid methyltransferase Steroid_dh PF02544.16 EGO24315.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase GFA PF04828.14 EGO24316.1 - 1e-10 41.8 4.1 2e-10 40.8 4.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TAP_C PF03943.13 EGO24319.1 - 3.4e-15 55.4 0.1 9.5e-15 54.0 0.1 1.8 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 EGO24319.1 - 1.2e-05 25.9 0.0 7.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 EGO24319.1 - 0.00051 19.6 0.0 0.0009 18.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat UBA_4 PF14555.6 EGO24319.1 - 0.0023 17.7 0.1 0.0062 16.3 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain LRR_4 PF12799.7 EGO24319.1 - 0.003 17.9 6.4 0.024 15.1 3.0 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO24319.1 - 2.4 8.0 7.1 13 5.6 7.1 2.2 1 1 0 1 1 1 0 Leucine rich repeat Vps39_1 PF10366.9 EGO24320.1 - 3.8e-29 101.1 0.3 2.5e-27 95.3 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EGO24320.1 - 4.8e-23 81.7 0.4 2.1e-22 79.6 0.4 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGO24320.1 - 1.1e-15 57.7 1.1 6.6e-10 39.0 0.3 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 EGO24320.1 - 5.6e-14 52.4 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 CNH domain ANAPC3 PF12895.7 EGO24320.1 - 0.0032 17.7 0.5 0.47 10.7 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGO24320.1 - 0.006 17.1 0.2 0.14 12.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24320.1 - 0.0081 16.1 0.4 17 5.7 0.4 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO24320.1 - 0.012 15.4 7.7 4.8 7.2 1.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO24320.1 - 0.055 13.6 2.6 26 5.2 0.4 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGO24320.1 - 0.083 12.9 1.3 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40_3 PF15911.5 EGO24320.1 - 0.15 12.1 0.2 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40_like PF17005.5 EGO24320.1 - 0.16 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Myb_DNA-bind_4 PF13837.6 EGO24322.1 - 0.00069 19.9 0.1 0.00091 19.6 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Topo_Zn_Ribbon PF08272.11 EGO24322.1 - 0.023 14.4 0.4 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like SPA PF08616.10 EGO24323.1 - 4.9e-07 29.7 0.0 9.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EGO24323.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MFS_1 PF07690.16 EGO24324.1 - 4.7e-27 94.8 22.8 4.7e-27 94.8 22.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.23 EGO24327.1 - 0.0036 17.3 4.1 0.0036 17.3 4.1 1.6 2 0 0 2 2 2 1 Zinc knuckle Peptidase_M60_C PF18630.1 EGO24327.1 - 0.053 13.6 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain DUF4939 PF16297.5 EGO24327.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4939) zf-CCHC_2 PF13696.6 EGO24327.1 - 1.6 8.6 3.8 3.5 7.5 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle ABC2_membrane PF01061.24 EGO24329.1 - 4.1e-35 121.1 20.1 4.1e-35 121.1 20.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGO24329.1 - 4.6e-27 95.2 0.0 8.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO24329.1 - 5.1e-05 23.2 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 EGO24329.1 - 8.7e-05 22.8 9.3 8.7e-05 22.8 9.3 3.7 4 0 0 4 4 2 2 EGF-like domain ABC2_membrane_3 PF12698.7 EGO24329.1 - 0.0013 18.0 22.3 0.0013 18.0 22.3 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGO24329.1 - 0.0014 18.3 0.1 0.0036 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EGO24329.1 - 0.0022 18.0 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGO24329.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGO24329.1 - 0.0098 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGO24329.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGO24329.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO24329.1 - 0.16 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGO24329.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_C7 PF01830.18 EGO24329.1 - 0.46 9.9 2.5 0.85 9.0 1.3 2.0 2 0 0 2 2 2 0 Peptidase C7 family Glyco_transf_22 PF03901.17 EGO24330.1 - 1.6e-35 123.2 21.2 4.8e-35 121.6 21.2 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4227 PF14004.6 EGO24330.1 - 0.15 12.1 2.5 2.8 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) UPF0014 PF03649.13 EGO24331.1 - 6.1e-73 245.1 13.4 7.5e-73 244.8 13.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Tubulin_2 PF13809.6 EGO24331.1 - 0.0026 17.0 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin like BPD_transp_1 PF00528.22 EGO24331.1 - 0.033 13.9 13.5 0.042 13.6 11.0 2.4 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component DUF5316 PF17247.2 EGO24331.1 - 4.6 7.3 11.0 1.6 8.8 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5316) OATP PF03137.20 EGO24331.1 - 7.6 4.7 10.7 0.27 9.5 3.3 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF724 PF05266.14 EGO24332.1 - 0.0012 18.7 12.1 0.0012 18.7 12.1 2.7 2 1 2 4 4 4 1 Protein of unknown function (DUF724) MscS_porin PF12795.7 EGO24332.1 - 0.051 13.1 37.4 0.01 15.4 25.3 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain MAD PF05557.13 EGO24332.1 - 0.095 11.0 33.9 0.14 10.5 33.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ORF6C PF10552.9 EGO24332.1 - 0.13 12.4 18.6 0.074 13.1 5.9 3.3 2 1 1 3 3 3 0 ORF6C domain TolA_bind_tri PF16331.5 EGO24332.1 - 0.17 12.0 34.2 1.1 9.4 6.9 3.7 3 0 0 3 3 3 0 TolA binding protein trimerisation EzrA PF06160.12 EGO24332.1 - 0.45 8.6 28.4 0.012 13.9 13.6 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 EGO24332.1 - 0.5 10.8 15.1 12 6.4 1.8 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Macoilin PF09726.9 EGO24332.1 - 0.54 8.8 32.9 0.18 10.4 29.7 1.7 1 1 1 2 2 2 0 Macoilin family Cob_adeno_trans PF01923.18 EGO24332.1 - 1.1 9.4 15.5 0.18 11.9 6.8 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spc24 PF08286.11 EGO24332.1 - 2 8.7 29.4 2.9 8.2 3.6 3.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FliJ PF02050.16 EGO24332.1 - 2 8.6 34.9 0.052 13.8 21.2 2.9 1 1 1 2 2 2 0 Flagellar FliJ protein Baculo_PEP_C PF04513.12 EGO24332.1 - 4 7.5 7.1 0.6 10.2 2.1 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EGO24332.1 - 4.7 6.5 31.6 1.7 7.9 27.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 EGO24332.1 - 8.5 6.5 32.3 0.56 10.2 11.2 4.1 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 EGO24332.1 - 8.8 5.1 35.8 0.91 8.3 23.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Pkinase PF00069.25 EGO24333.1 - 6.1e-43 147.1 0.0 8.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO24333.1 - 8.4e-24 84.2 0.2 1.3e-20 73.8 0.1 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO24333.1 - 1.5e-05 24.0 0.0 1.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO24333.1 - 5.3e-05 23.3 0.0 0.0082 16.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO24333.1 - 0.017 14.4 0.1 0.16 11.3 0.1 2.0 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EGO24333.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Zn-ribbon_8 PF09723.10 EGO24334.1 - 0.18 11.9 6.3 7.4 6.8 6.3 2.1 1 1 0 1 1 1 0 Zinc ribbon domain Aminotran_1_2 PF00155.21 EGO24335.1 - 4.5e-26 91.9 0.0 5.6e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGO24335.1 - 1.3e-08 34.1 0.0 1.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ISG65-75 PF11727.8 EGO24335.1 - 0.018 14.3 0.0 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein zf-CCHC PF00098.23 EGO24336.1 - 8.4e-08 32.0 1.2 1.2e-07 31.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO24336.1 - 0.0087 15.6 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCHC_6 PF15288.6 EGO24336.1 - 0.13 12.1 1.5 0.22 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO24338.1 - 0.00038 20.7 0.4 0.00038 20.7 0.4 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein DUF4290 PF14123.6 EGO24340.1 - 0.05 13.2 0.6 0.1 12.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) ADH_zinc_N PF00107.26 EGO24341.1 - 2e-09 37.5 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO24341.1 - 7.9e-09 35.4 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ala_racemase_N PF01168.20 EGO24343.1 - 2.4e-17 63.3 0.0 2.9e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4253 PF14062.6 EGO24343.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) MIS13 PF08202.11 EGO24344.1 - 1.3e-29 103.5 3.0 2.8e-29 102.4 3.0 1.5 1 1 0 1 1 1 1 Mis12-Mtw1 protein family DHHC PF01529.20 EGO24345.1 - 5.5e-27 94.5 8.5 5.5e-27 94.5 8.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase FtsX PF02687.21 EGO24345.1 - 2.3 8.7 10.8 0.14 12.7 5.0 1.8 2 0 0 2 2 2 0 FtsX-like permease family GST_N PF02798.20 EGO24347.1 - 1.4e-18 66.9 0.0 2.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO24347.1 - 3.4e-15 56.2 0.0 6.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO24347.1 - 2.7e-14 53.1 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO24347.1 - 2.2e-11 43.9 0.0 4.9e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO24347.1 - 1.3e-06 28.4 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO24347.1 - 7.7e-06 26.0 0.0 2.2e-05 24.6 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.10 EGO24347.1 - 0.0087 16.2 0.3 0.022 14.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1912) GST_N PF02798.20 EGO24348.1 - 7.2e-14 51.9 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO24348.1 - 8.6e-14 51.7 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO24348.1 - 4.8e-10 39.6 0.0 8.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO24348.1 - 1.2e-09 38.2 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO24348.1 - 0.00046 20.3 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO24348.1 - 0.00053 19.9 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 EGO24349.1 - 2.7e-48 164.9 0.0 4.9e-36 124.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cyclin_C_2 PF16899.5 EGO24351.1 - 6.9e-23 81.0 0.0 4.4e-20 72.0 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EGO24351.1 - 1.3e-10 41.1 0.1 6.5e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGO24351.1 - 0.00022 21.2 0.0 0.0063 16.5 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF1764 PF08576.10 EGO24352.1 - 1.4e-24 86.8 17.8 3.8e-23 82.3 7.9 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) DUF4551 PF15087.6 EGO24352.1 - 2.7 6.7 4.4 2.9 6.6 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 EGO24352.1 - 6.5 5.4 4.9 7.4 5.2 4.9 1.0 1 0 0 1 1 1 0 Presenilin ACBP PF00887.19 EGO24355.1 - 3e-29 101.1 0.6 3.7e-29 100.8 0.6 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein GBR_NSP5 PF17580.2 EGO24355.1 - 0.024 14.5 0.3 0.03 14.1 0.3 1.1 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 PH PF00169.29 EGO24356.1 - 5.1e-35 120.2 1.5 8.7e-19 68.0 0.3 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 EGO24356.1 - 1.4e-16 60.9 7.2 9e-08 32.5 1.7 3.7 2 2 1 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.6 EGO24356.1 - 1.4e-10 41.1 0.1 1.3e-05 25.2 0.1 3.7 3 1 0 3 3 3 2 PH domain PH_8 PF15409.6 EGO24356.1 - 6.1e-09 36.0 2.0 6e-07 29.7 0.3 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH_13 PF16652.5 EGO24356.1 - 0.00017 21.5 0.0 0.013 15.3 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGO24356.1 - 0.00052 20.4 3.1 0.085 13.2 1.4 3.3 2 2 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 EGO24356.1 - 0.0041 17.4 0.0 3.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_4 PF15404.6 EGO24356.1 - 0.07 12.9 0.3 0.66 9.8 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain PH_12 PF16457.5 EGO24356.1 - 0.089 13.3 4.0 0.38 11.3 0.0 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 EGO24356.1 - 0.33 11.1 6.7 6.7 6.8 0.0 3.1 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Zn_clus PF00172.18 EGO24357.1 - 1.4e-05 25.1 7.6 2.3e-05 24.4 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO24358.1 - 5e-35 121.0 0.0 5.7e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EGO24359.1 - 4.3e-49 167.3 0.5 7.1e-49 166.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO24359.1 - 8.7e-06 25.8 10.0 1.4e-05 25.1 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drf_GBD PF06371.13 EGO24360.1 - 3.9e-16 59.2 0.0 2.4e-12 46.8 0.0 2.5 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain GMC_oxred_N PF00732.19 EGO24361.1 - 4.3e-67 226.6 0.0 5.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO24361.1 - 4.2e-35 121.4 0.0 7.4e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO24361.1 - 1e-06 28.1 1.2 0.0012 18.0 0.6 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EGO24361.1 - 4.4e-06 26.0 0.3 7.3e-06 25.3 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EGO24361.1 - 9.5e-06 25.4 1.2 0.00039 20.1 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO24361.1 - 3.8e-05 23.1 0.3 7.6e-05 22.1 0.1 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGO24361.1 - 4e-05 23.8 0.1 0.0001 22.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO24361.1 - 0.00051 19.4 0.1 0.0035 16.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO24361.1 - 0.011 16.2 0.0 0.065 13.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO24361.1 - 0.019 13.7 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EGO24361.1 - 0.026 14.5 1.2 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGO24361.1 - 0.052 12.4 0.2 0.078 11.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EGO24361.1 - 0.28 10.4 0.6 0.43 9.8 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EGO24361.1 - 0.39 9.9 0.8 1.6 7.9 0.2 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO24361.1 - 0.57 9.5 3.8 11 5.2 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase PEMT PF04191.13 EGO24362.1 - 4.7e-10 39.8 4.6 4.1e-08 33.6 1.5 2.2 1 1 1 2 2 2 2 Phospholipid methyltransferase ICMT PF04140.14 EGO24362.1 - 8.5e-09 35.7 0.6 8.5e-09 35.7 0.6 2.5 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EGO24362.1 - 0.042 12.6 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EGO24365.1 - 9.1e-13 48.5 0.1 1.7e-11 44.4 0.0 2.2 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO24365.1 - 1.3e-10 41.6 0.1 5.3e-09 36.4 0.0 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGO24365.1 - 0.04 12.7 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 EGO24366.1 - 2.3e-14 53.5 0.7 9e-13 48.5 0.1 2.3 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO24366.1 - 9e-13 48.5 0.4 5.1e-11 42.9 0.4 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGO24366.1 - 1.7e-05 23.8 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CENP-Q PF13094.6 EGO24370.1 - 0.92 9.7 8.2 2 8.6 8.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF848 PF05852.11 EGO24372.1 - 0.0038 17.3 2.6 0.0049 17.0 2.6 1.2 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Shugoshin_N PF07558.11 EGO24372.1 - 0.0069 16.2 1.3 0.015 15.2 1.3 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Cnn_1N PF07989.11 EGO24372.1 - 0.018 15.2 6.2 0.027 14.6 5.8 1.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 HAUS6_N PF14661.6 EGO24372.1 - 0.018 14.6 3.3 0.021 14.4 3.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_2 PF07716.15 EGO24372.1 - 0.024 14.7 2.8 0.065 13.3 2.8 1.8 1 0 0 1 1 1 0 Basic region leucine zipper TMCO5 PF14992.6 EGO24372.1 - 0.03 13.9 6.3 0.037 13.6 6.3 1.1 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.15 EGO24372.1 - 0.035 13.9 3.0 0.035 13.9 3.0 1.7 2 0 0 2 2 2 0 Septum formation initiator FANCI_HD1 PF14679.6 EGO24372.1 - 0.037 14.0 0.4 0.065 13.2 0.4 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 CENP-H PF05837.12 EGO24372.1 - 0.041 14.3 3.9 0.041 14.3 3.9 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF724 PF05266.14 EGO24372.1 - 0.053 13.3 4.1 0.061 13.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GNAT_acetyltr_2 PF13718.6 EGO24372.1 - 0.074 12.4 1.1 0.088 12.2 1.1 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase 2 NRBF2 PF08961.10 EGO24372.1 - 0.096 12.3 3.3 0.13 11.9 3.3 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator V_ATPase_I PF01496.19 EGO24372.1 - 0.13 10.2 4.5 0.15 9.9 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 EGO24372.1 - 0.18 11.9 5.3 0.075 13.1 2.8 1.7 2 0 0 2 2 2 0 bZIP transcription factor ICMT PF04140.14 EGO24373.1 - 0.00035 20.9 0.0 0.0006 20.2 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO24373.1 - 0.13 12.7 0.1 0.13 12.7 0.1 1.5 2 0 0 2 2 2 0 Phospholipid methyltransferase SMN PF06003.12 EGO24374.1 - 8.6e-08 31.7 0.9 1.2e-07 31.2 0.9 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 EGO24374.1 - 7.9e-05 22.7 0.0 0.00019 21.5 0.0 1.8 1 1 0 1 1 1 1 Tudor domain Tudor_3 PF18115.1 EGO24374.1 - 0.0006 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Relaxase PF03432.14 EGO24374.1 - 0.0069 16.0 4.0 0.011 15.4 3.0 1.7 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain RRP36 PF06102.12 EGO24374.1 - 0.01 15.8 11.0 0.01 15.8 11.0 1.9 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Jak1_Phl PF17887.1 EGO24374.1 - 0.052 13.5 2.8 0.11 12.4 2.8 1.6 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain RR_TM4-6 PF06459.12 EGO24374.1 - 0.1 12.4 8.4 0.18 11.6 8.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Agenet PF05641.12 EGO24374.1 - 0.11 12.9 0.3 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 Agenet domain DUF4672 PF15716.5 EGO24374.1 - 0.6 9.7 6.7 0.97 9.0 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) PDCD2_C PF04194.13 EGO24374.1 - 3.6 7.6 8.8 0.97 9.5 5.9 1.5 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain FemAB PF02388.16 EGO24374.1 - 3.9 6.3 11.2 1.2 7.9 7.8 1.7 2 0 0 2 2 2 0 FemAB family Hid1 PF12722.7 EGO24375.1 - 0.35 8.9 1.3 0.46 8.5 1.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-CCHC_3 PF13917.6 EGO24376.1 - 1.1e-06 28.4 1.6 1.2e-06 28.4 1.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO24376.1 - 2.6e-06 27.3 5.0 3.3e-06 26.9 5.0 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO24376.1 - 0.016 14.7 0.9 0.023 14.2 0.9 1.3 1 0 0 1 1 1 0 Copper fist DNA binding domain NAD_binding_10 PF13460.6 EGO24378.1 - 1.6e-11 44.4 0.1 2.6e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO24378.1 - 1.6e-08 34.3 0.0 0.00061 19.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO24378.1 - 2.4e-08 33.8 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EGO24378.1 - 1.4e-06 28.7 0.1 3.3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGO24378.1 - 5.7e-05 23.4 0.0 0.00014 22.1 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGO24378.1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EGO24378.1 - 0.00035 19.8 0.0 0.0015 17.8 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO24378.1 - 0.0011 18.4 0.0 0.41 10.0 0.0 2.8 2 1 1 3 3 3 2 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EGO24378.1 - 0.0029 18.2 0.0 0.0077 16.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EGO24378.1 - 0.0093 15.0 0.0 0.024 13.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EGO24378.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ICMT PF04140.14 EGO24380.1 - 0.0065 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family tRNA-synt_1g PF09334.11 EGO24381.1 - 3.8e-137 457.2 0.0 4.9e-137 456.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGO24381.1 - 5.1e-07 29.8 0.0 1.2e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA WHEP-TRS PF00458.20 EGO24381.1 - 2.3e-06 27.7 9.7 2.3e-06 27.7 9.7 2.1 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 EGO24381.1 - 1.7e-05 23.3 0.1 0.0014 16.9 0.0 3.2 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) DUF1610 PF07754.11 EGO24381.1 - 0.088 12.8 3.3 0.18 11.8 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF1272 PF06906.11 EGO24381.1 - 0.41 10.8 4.5 0.17 12.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 EGO24381.1 - 0.5 10.4 5.0 1.7 8.7 5.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF1289 PF06945.13 EGO24381.1 - 0.94 9.3 5.6 12 5.8 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) OPT PF03169.15 EGO24382.1 - 3.8e-135 451.9 21.5 4.9e-135 451.6 21.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 EGO24382.1 - 0.013 15.5 2.3 0.77 9.8 0.1 3.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S DUF1673 PF07895.11 EGO24382.1 - 0.032 13.9 3.0 1.1 8.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) MFS_1 PF07690.16 EGO24383.1 - 2.3e-19 69.5 23.2 6.9e-19 68.0 14.4 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 EGO24383.1 - 0.00026 19.4 0.3 0.0016 16.8 0.0 2.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family HemY_N PF07219.13 EGO24383.1 - 0.077 13.2 1.1 2.7 8.2 0.3 2.9 2 0 0 2 2 2 0 HemY protein N-terminus p450 PF00067.22 EGO24385.1 - 4e-51 174.2 0.0 7.2e-51 173.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF4791 PF16039.5 EGO24385.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) EGF_CA PF07645.15 EGO24387.1 - 0.031 14.5 2.3 0.047 13.9 2.3 1.5 1 1 0 1 1 1 0 Calcium-binding EGF domain Pex14_N PF04695.13 EGO24389.1 - 0.12 13.0 10.7 0.39 11.4 10.7 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rrn6 PF10214.9 EGO24389.1 - 0.17 10.4 11.9 0.23 9.9 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5583 PF17821.1 EGO24389.1 - 1.2 9.0 6.0 2.2 8.3 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5583) TFIIA PF03153.13 EGO24389.1 - 2.4 8.1 9.7 3.3 7.6 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 EGO24390.1 - 2.3e-57 194.8 0.0 3.8e-57 194.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DUF4791 PF16039.5 EGO24390.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) CHAT PF12770.7 EGO24391.1 - 2e-25 89.8 0.2 5e-24 85.2 0.1 2.3 1 1 1 2 2 2 1 CHAT domain TPR_12 PF13424.6 EGO24391.1 - 2.7e-13 50.0 21.1 0.55 10.6 0.1 11.9 6 3 6 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGO24391.1 - 6.2e-13 48.0 19.0 0.37 10.7 0.0 9.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGO24391.1 - 6.5e-11 41.7 17.8 0.0032 17.3 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO24391.1 - 4.2e-09 36.2 5.4 0.29 11.6 0.0 8.6 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO24391.1 - 3e-08 33.2 11.6 0.034 13.8 2.0 7.7 8 0 0 8 8 8 1 TPR repeat TPR_2 PF07719.17 EGO24391.1 - 7.7e-07 28.8 14.8 0.39 10.9 0.4 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO24391.1 - 1.6e-06 27.9 8.5 2.8 8.4 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO24391.1 - 3.8e-05 24.2 24.6 0.16 12.6 0.0 8.3 6 2 2 9 9 8 3 Tetratricopeptide repeat Sel1 PF08238.12 EGO24391.1 - 0.0006 20.4 6.7 16 6.3 0.0 7.8 9 0 0 9 9 8 0 Sel1 repeat TPR_19 PF14559.6 EGO24391.1 - 0.045 14.3 9.9 1.1e+02 3.5 2.1 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 EGO24391.1 - 0.31 11.1 11.4 31 4.7 0.1 6.0 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 EGO24391.1 - 0.85 10.6 21.8 14 6.8 0.0 9.2 9 1 2 11 11 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24391.1 - 2.7 8.2 15.3 28 5.1 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat Fra10Ac1 PF09725.9 EGO24394.1 - 8.4e-49 164.8 0.1 1.2e-48 164.3 0.1 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_11 PF00457.17 EGO24394.1 - 0.0065 16.1 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 TPR_2 PF07719.17 EGO24395.1 - 0.00056 19.8 12.3 0.46 10.7 1.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 EGO24395.1 - 0.16 12.0 0.8 4.6 7.3 0.0 3.4 2 1 2 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 EGO24395.1 - 0.33 10.9 9.9 3.4 7.6 1.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO24395.1 - 0.65 10.5 3.5 17 6.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO24395.1 - 0.83 9.4 8.5 0.33 10.7 0.8 3.0 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 EGO24395.1 - 3.9 7.8 6.6 2.5 8.4 1.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ctf8 PF09696.10 EGO24397.1 - 6e-16 59.1 1.3 2.5e-14 53.8 1.3 2.1 1 1 0 1 1 1 1 Ctf8 Lipase_3 PF01764.25 EGO24398.1 - 4.4e-07 29.9 0.0 3.3e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO24398.1 - 0.082 13.5 0.7 0.21 12.2 0.7 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO24398.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase PF00151.19 EGO24398.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Lipase UPF0227 PF05728.12 EGO24398.1 - 0.18 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Trehalase PF01204.18 EGO24399.1 - 1.3e-167 558.7 0.1 1.6e-167 558.4 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EGO24399.1 - 8e-15 54.3 0.1 1.4e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ATG22 PF11700.8 EGO24402.1 - 2.6e-120 402.3 26.6 3e-120 402.1 26.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TraS PF10624.9 EGO24402.1 - 0.18 11.7 4.7 0.44 10.5 4.7 1.6 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS TssN PF17555.2 EGO24402.1 - 6.1 6.2 20.2 0.096 12.1 10.2 2.4 1 1 1 2 2 2 0 Type VI secretion system, TssN Mitofilin PF09731.9 EGO24403.1 - 2.4e-115 386.8 20.5 2.8e-115 386.5 20.5 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3158 PF11358.8 EGO24403.1 - 0.0046 16.7 0.6 0.012 15.3 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3158) Terpene_synth_C PF03936.16 EGO24404.1 - 0.0065 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain YebO PF13974.6 EGO24404.1 - 0.28 11.3 2.1 0.8 9.8 0.7 2.5 3 0 0 3 3 3 0 YebO-like protein DASH_Spc34 PF08657.10 EGO24404.1 - 0.37 10.6 2.3 5.6 6.7 0.0 2.2 1 1 1 2 2 2 0 DASH complex subunit Spc34 Nucleoporin_FG PF13634.6 EGO24405.1 - 8e-06 26.6 32.6 8e-06 26.6 32.6 4.2 2 1 2 4 4 3 1 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 EGO24405.1 - 0.00017 20.3 53.9 0.02 13.4 53.9 3.0 1 1 0 1 1 1 1 Nucleoporin FG repeated region Dynein_C PF18199.1 EGO24405.1 - 0.0077 15.5 0.1 1.2 8.3 0.0 2.4 1 1 1 2 2 2 2 Dynein heavy chain C-terminal domain AceK PF06315.11 EGO24405.1 - 0.0098 14.4 1.1 0.014 13.9 1.1 1.2 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) PHM7_cyt PF14703.6 EGO24405.1 - 0.011 16.0 1.7 0.022 15.0 1.7 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1944 PF09175.10 EGO24405.1 - 0.057 13.3 0.1 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) KxDL PF10241.9 EGO24405.1 - 0.065 13.5 6.1 4.1 7.8 0.2 3.7 2 2 2 4 4 4 0 Uncharacterized conserved protein Uso1_p115_C PF04871.13 EGO24405.1 - 0.083 13.3 1.2 0.16 12.3 1.2 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Occludin_ELL PF07303.13 EGO24405.1 - 0.1 13.3 4.8 25 5.7 0.1 3.5 1 1 1 3 3 3 0 Occludin homology domain V-SNARE_C PF12352.8 EGO24405.1 - 0.45 10.8 3.0 10 6.5 0.8 3.4 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus UPF0242 PF06785.11 EGO24405.1 - 0.46 10.6 3.7 0.83 9.7 3.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 EGO24405.1 - 0.87 9.1 6.9 0.76 9.3 1.9 2.0 2 0 0 2 2 2 0 Intermediate filament protein PRKG1_interact PF15898.5 EGO24405.1 - 1.6 9.7 4.2 0.61 11.0 1.1 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Arrestin_N PF00339.29 EGO24406.1 - 7.8e-05 22.8 0.6 0.002 18.2 0.6 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Mito_carr PF00153.27 EGO24407.1 - 1.7e-56 188.2 2.7 8.6e-21 73.7 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Transket_pyr PF02779.24 EGO24407.1 - 0.15 11.7 0.3 5.5 6.6 0.2 2.3 1 1 1 2 2 2 0 Transketolase, pyrimidine binding domain Amidohydro_1 PF01979.20 EGO24410.1 - 8.6e-69 232.4 1.0 1.3e-68 231.9 1.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGO24410.1 - 5.2e-57 191.4 1.9 1.1e-56 190.4 1.9 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EGO24410.1 - 1.9e-39 133.9 0.0 4e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 EGO24410.1 - 1.7e-38 130.6 0.0 3.4e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 EGO24410.1 - 3e-08 33.6 0.3 3.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family TnpV PF14198.6 EGO24412.1 - 0.061 13.3 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DnaJ_C PF01556.18 EGO24416.1 - 6.3e-24 84.7 0.0 1e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO24416.1 - 1.2e-18 66.9 0.2 4.1e-18 65.3 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 EGO24418.1 - 1.8e-38 131.9 0.0 2.4e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO24418.1 - 2.2e-27 95.0 0.2 3.3e-27 94.4 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGO24418.1 - 0.24 11.4 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein DEAD PF00270.29 EGO24419.1 - 1.1e-33 116.5 0.0 1.8e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO24419.1 - 9.2e-27 93.6 0.3 2.6e-26 92.1 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGO24419.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 EGO24419.1 - 0.062 12.6 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EGO24419.1 - 0.22 11.8 1.3 1.9 8.8 0.6 2.7 2 1 0 2 2 2 0 AAA domain DUF1729 PF08354.10 EGO24420.1 - 6e-149 495.7 0.0 9.8e-149 495.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 EGO24420.1 - 6.7e-74 247.9 0.5 1.9e-73 246.4 0.1 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 EGO24420.1 - 1e-71 242.1 0.1 1.5e-70 238.2 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 EGO24420.1 - 3.3e-70 235.6 0.0 8.8e-70 234.2 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 EGO24420.1 - 1.2e-49 167.9 0.0 2.8e-49 166.7 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EGO24420.1 - 4.3e-36 124.8 0.1 1.3e-35 123.3 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EGO24420.1 - 5.6e-28 97.0 0.0 2.2e-27 95.1 0.0 2.1 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 EGO24420.1 - 4.7e-26 91.9 0.2 1.1e-25 90.6 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 EGO24420.1 - 3.7e-25 88.4 3.2 9.5e-25 87.1 3.2 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Ketoacyl-synt_C PF02801.22 EGO24420.1 - 1.8e-16 60.2 0.1 3.7e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 EGO24420.1 - 3.3e-14 53.0 0.0 8.2e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 EGO24420.1 - 1.5e-12 47.8 1.2 1.1e-11 45.0 0.0 2.9 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 EGO24420.1 - 7.4e-06 25.6 0.0 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase DUF4061 PF13270.6 EGO24420.1 - 0.042 14.2 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) KR PF08659.10 EGO24420.1 - 0.14 12.1 0.3 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 KR domain CHB_HEX_C_1 PF13290.6 EGO24420.1 - 0.15 12.1 0.1 0.49 10.4 0.1 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Gtr1_RagA PF04670.12 EGO24421.1 - 6e-49 166.5 0.0 7.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO24421.1 - 0.0069 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGO24421.1 - 0.0071 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO24421.1 - 0.0097 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO24421.1 - 0.015 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGO24421.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EGO24421.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGO24421.1 - 0.14 11.3 0.4 0.3 10.2 0.4 1.8 1 1 0 1 1 1 0 G-protein alpha subunit VTC PF09359.10 EGO24422.1 - 2.6e-94 315.7 0.5 1.2e-93 313.5 0.0 2.2 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 EGO24422.1 - 2e-17 64.2 20.5 3.5e-06 27.2 0.1 4.2 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 EGO24422.1 - 2.3e-11 44.0 1.0 4.7e-11 43.0 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF1319 PF07028.11 EGO24422.1 - 0.029 14.6 2.3 2.6 8.3 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1319) DUF2570 PF10828.8 EGO24422.1 - 0.15 11.9 1.4 0.85 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Polysacc_synt_C PF14667.6 EGO24422.1 - 0.62 10.1 5.3 0.96 9.5 5.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PTPlike_phytase PF14566.6 EGO24423.1 - 6.7e-137 451.9 0.0 1.6e-47 161.5 0.0 3.8 4 0 0 4 4 4 3 Inositol hexakisphosphate DSPc PF00782.20 EGO24423.1 - 3.6e-05 23.6 0.0 0.018 14.9 0.0 3.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO24423.1 - 0.00019 21.1 0.0 0.73 9.4 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DUF1651 PF07864.11 EGO24423.1 - 0.17 12.3 0.5 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) Ribosomal_S3_C PF00189.20 EGO24424.1 - 4e-25 88.2 0.1 1.5e-24 86.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGO24424.1 - 7.9e-12 44.8 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EGO24424.1 - 0.074 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EGO24424.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF5565 PF17720.1 EGO24426.1 - 0.068 12.0 0.0 0.075 11.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5565) CVNH PF08881.10 EGO24427.1 - 1.1e-16 61.4 1.3 1.3e-16 61.1 1.3 1.1 1 0 0 1 1 1 1 CVNH domain Zn_Tnp_IS91 PF14319.6 EGO24427.1 - 4.8 7.3 9.9 1.6 8.8 7.0 1.7 2 0 0 2 2 2 0 Transposase zinc-binding domain MARVEL PF01284.23 EGO24428.1 - 0.0039 17.2 8.7 0.006 16.6 8.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain AhpC-TSA PF00578.21 EGO24429.1 - 9.2e-05 22.4 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO24429.1 - 0.0059 16.3 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin eIF-6 PF01912.18 EGO24430.1 - 4.5e-82 274.2 0.3 4.5e-82 274.2 0.3 1.7 2 0 0 2 2 2 1 eIF-6 family Methyltransf_28 PF02636.17 EGO24431.1 - 8.5e-68 228.8 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EGO24431.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase GMC_oxred_N PF00732.19 EGO24432.1 - 1.9e-62 211.3 0.0 2.5e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO24432.1 - 6.3e-40 137.0 0.0 1.1e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EGO24432.1 - 6e-06 26.1 0.1 0.00011 22.0 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGO24432.1 - 4.4e-05 22.7 0.6 7.7e-05 21.9 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EGO24432.1 - 5.2e-05 22.6 0.1 0.0003 20.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGO24432.1 - 0.00015 21.9 0.2 0.00052 20.2 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO24432.1 - 0.00026 20.2 1.3 0.018 14.2 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGO24432.1 - 0.033 13.4 0.1 0.096 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO24432.1 - 0.048 12.3 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EGO24432.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGO24432.1 - 0.13 12.2 0.3 0.3 11.1 0.2 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGO24432.1 - 0.14 12.8 2.5 0.61 10.7 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO24432.1 - 0.2 10.4 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RhoGAP PF00620.27 EGO24433.1 - 3.4e-39 134.1 0.0 5.1e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_17 PF00332.18 EGO24434.1 - 2.4e-08 34.0 0.9 7.2e-07 29.1 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Varsurf_PPLC PF03490.13 EGO24434.1 - 0.096 12.7 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C COQ9 PF08511.11 EGO24436.1 - 6.5e-05 22.6 0.7 0.00012 21.8 0.1 1.8 2 0 0 2 2 2 1 COQ9 Vps51 PF08700.11 EGO24438.1 - 1.8e-23 82.4 1.6 2.6e-23 81.9 1.6 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 EGO24438.1 - 0.0013 17.5 1.9 0.0017 17.1 1.9 1.0 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.12 EGO24438.1 - 0.004 17.7 1.8 0.0056 17.2 1.8 1.1 1 0 0 1 1 1 1 FlgN protein COG5 PF10392.9 EGO24438.1 - 0.012 15.8 1.8 0.017 15.3 1.8 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Bap31_Bap29_C PF18035.1 EGO24438.1 - 0.014 15.4 0.3 0.027 14.5 0.3 1.6 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4756 PF15948.5 EGO24438.1 - 0.065 13.1 0.2 0.099 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) p450 PF00067.22 EGO24439.1 - 1.4e-75 254.9 0.0 1.8e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Imm32 PF15566.6 EGO24439.1 - 0.02 14.7 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 32 ATP_synt_H PF05493.13 EGO24440.1 - 3.7e-21 75.3 4.6 4.3e-21 75.1 4.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 EGO24440.1 - 0.32 10.6 1.7 0.36 10.4 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Potass_KdpF PF09604.10 EGO24440.1 - 6 7.0 9.1 0.86 9.7 4.1 2.0 2 0 0 2 2 2 0 F subunit of K+-transporting ATPase (Potass_KdpF) Methyltransf_23 PF13489.6 EGO24441.1 - 0.0029 17.5 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO24441.1 - 0.06 14.1 0.0 7.2 7.4 0.1 2.5 1 1 1 2 2 2 0 Methyltransferase domain G-alpha PF00503.20 EGO24442.1 - 1.5e-124 415.7 0.0 1.8e-124 415.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO24442.1 - 6.9e-13 48.4 0.1 1.8e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 EGO24442.1 - 0.00026 20.6 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGO24442.1 - 0.00063 20.0 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGO24442.1 - 0.0066 15.9 0.1 0.084 12.3 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EGO24442.1 - 0.039 13.7 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 EGO24442.1 - 0.079 12.3 0.2 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EGO24442.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3567 PF12091.8 EGO24442.1 - 0.11 12.7 0.0 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) THUMP PF02926.17 EGO24443.1 - 1.2e-08 35.2 0.6 2.7e-08 34.0 0.0 1.8 3 0 0 3 3 3 1 THUMP domain ORC5_C PF14630.6 EGO24443.1 - 0.13 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus HLH PF00010.26 EGO24444.1 - 3.3e-06 26.9 0.0 1.1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRCC PF10253.9 EGO24444.1 - 2.8 8.7 16.5 0.1 13.4 9.0 2.0 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting NUDIX PF00293.28 EGO24445.1 - 1.7e-13 50.7 0.4 2.1e-13 50.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.22 EGO24446.1 - 1.2e-47 162.8 19.3 1.4e-45 156.0 19.3 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter HD PF01966.22 EGO24447.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 HD domain GMC_oxred_N PF00732.19 EGO24448.1 - 1e-63 215.5 0.0 1.4e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO24448.1 - 2e-34 119.2 0.0 3.7e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO24448.1 - 0.00027 20.1 0.5 0.25 10.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EGO24448.1 - 0.00042 19.5 0.2 0.0018 17.4 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EGO24448.1 - 0.00069 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGO24448.1 - 0.0072 16.5 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO24448.1 - 0.018 14.6 0.5 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO24448.1 - 0.11 11.8 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PEX11 PF05648.14 EGO24450.1 - 7.7e-12 45.2 0.1 8.7e-10 38.4 0.1 2.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Glyco_hydro_10 PF00331.20 EGO24451.1 - 1.1e-100 336.9 0.0 1.4e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EGO24451.1 - 0.051 12.9 0.1 0.31 10.3 0.0 1.9 1 1 1 2 2 2 0 Beta-galactosidase NTP_transf_9 PF04248.12 EGO24452.1 - 7.8e-41 137.9 0.5 9.2e-29 99.2 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF427) DUF1080 PF06439.11 EGO24452.1 - 0.17 12.0 0.1 0.8 9.8 0.0 2.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1080) eIF-5_eIF-2B PF01873.17 EGO24453.1 - 2e-38 130.9 0.0 4.2e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EGO24453.1 - 4.1e-25 87.7 7.3 4.3e-24 84.5 0.1 3.2 3 1 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon Sigma70_ner PF04546.13 EGO24453.1 - 0.017 15.0 0.3 0.017 15.0 0.3 2.0 3 0 0 3 3 3 0 Sigma-70, non-essential region GSHPx PF00255.19 EGO24454.1 - 5.2e-41 138.6 0.1 6.6e-41 138.3 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EGO24454.1 - 0.00037 20.4 0.1 0.0019 18.1 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO24454.1 - 0.0035 17.1 0.1 0.0077 16.0 0.1 1.7 1 1 0 1 1 1 1 Redoxin Putative_PNPOx PF01243.20 EGO24455.1 - 1.1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Metallophos PF00149.28 EGO24457.1 - 1.7e-11 45.1 0.0 3.7e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EGO24457.1 - 0.0062 14.9 1.5 0.024 13.0 0.0 2.2 3 0 0 3 3 3 1 Firmicute fructose-1,6-bisphosphatase AAA PF00004.29 EGO24459.1 - 7.5e-42 142.9 0.0 1.3e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO24459.1 - 2.6e-11 43.3 0.0 5.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGO24459.1 - 6.3e-10 38.7 0.6 1.2e-09 37.8 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGO24459.1 - 5.1e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGO24459.1 - 3.2e-05 23.2 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGO24459.1 - 4.5e-05 23.7 0.3 0.027 14.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EGO24459.1 - 0.00021 21.3 0.2 0.0013 18.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO24459.1 - 0.00023 21.6 0.2 0.0094 16.3 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGO24459.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 EGO24459.1 - 0.0019 17.8 0.6 0.0071 16.0 0.0 2.3 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EGO24459.1 - 0.0053 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGO24459.1 - 0.0068 16.3 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGO24459.1 - 0.0071 15.7 0.2 0.26 10.6 0.1 2.3 1 1 0 2 2 2 1 KaiC AAA_18 PF13238.6 EGO24459.1 - 0.0081 16.7 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO24459.1 - 0.015 15.5 0.5 0.095 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO24459.1 - 0.018 15.1 0.1 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGO24459.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EGO24459.1 - 0.063 13.2 0.1 0.78 9.6 0.1 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 EGO24459.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 EGO24459.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EGO24459.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EGO24459.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGO24459.1 - 0.11 12.3 0.2 0.34 10.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGO24459.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 EGO24459.1 - 0.14 11.3 0.1 0.6 9.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EGO24459.1 - 0.16 11.5 0.8 5.2 6.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EGO24459.1 - 0.18 11.5 0.4 0.41 10.3 0.4 1.6 1 1 0 1 1 1 0 AAA domain Yip1 PF04893.17 EGO24460.1 - 1e-13 51.3 18.6 1.5e-13 50.8 18.6 1.2 1 0 0 1 1 1 1 Yip1 domain Phosphonate-bd PF12974.7 EGO24461.1 - 3.5e-08 33.3 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EGO24461.1 - 4e-05 23.7 0.0 0.00012 22.1 0.0 1.7 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 EGO24461.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EGO24461.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 EGO24461.1 - 0.041 13.6 0.0 0.079 12.6 0.0 1.4 1 1 0 1 1 1 0 NMT1-like family STE3 PF02076.15 EGO24462.1 - 1.1e-65 221.7 18.6 1.2e-65 221.6 18.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor BRK PF07533.16 EGO24467.1 - 0.04 13.5 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 BRK domain GST_N_4 PF17172.4 EGO24468.1 - 1.9e-27 95.9 0.0 3.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGO24468.1 - 6.1e-13 49.2 0.0 8.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGO24468.1 - 1.9e-05 24.3 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO24468.1 - 0.00045 20.6 0.0 0.0015 18.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO24468.1 - 0.0015 18.5 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO24468.1 - 0.004 17.3 0.0 0.014 15.6 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain APG17 PF04108.12 EGO24469.1 - 1.6e-82 277.8 11.5 1.9e-82 277.5 11.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4335 PF14233.6 EGO24469.1 - 0.032 14.1 0.5 0.11 12.4 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4335) Sigma70_ner PF04546.13 EGO24469.1 - 0.076 12.9 5.8 0.03 14.2 0.7 2.2 1 1 1 2 2 2 0 Sigma-70, non-essential region Ku_C PF03730.14 EGO24469.1 - 0.12 13.1 1.7 0.28 11.9 0.5 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Mis14 PF08641.12 EGO24469.1 - 0.13 12.6 10.0 0.037 14.3 2.1 3.1 4 0 0 4 4 4 0 Kinetochore protein Mis14 like Spectrin_like PF18373.1 EGO24469.1 - 0.16 12.1 5.4 2.9 8.0 0.8 3.4 3 0 0 3 3 3 0 Spectrin like domain PHM7_cyt PF14703.6 EGO24469.1 - 0.22 11.7 0.9 0.51 10.5 0.2 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF948 PF06103.11 EGO24469.1 - 0.24 11.7 6.7 2.5 8.4 0.2 4.1 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 EGO24469.1 - 1.2 8.0 3.6 0.97 8.3 2.1 1.5 1 1 0 2 2 2 0 LMBR1-like membrane protein CK2S PF15011.6 EGO24469.1 - 1.3 8.8 11.5 4 7.3 6.8 3.3 1 1 2 3 3 3 0 Casein Kinase 2 substrate K-box PF01486.17 EGO24469.1 - 1.4 9.1 9.1 0.24 11.6 3.0 2.6 2 1 0 2 2 2 0 K-box region Spc7 PF08317.11 EGO24469.1 - 1.5 7.6 15.2 0.16 10.9 9.9 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein ALIX_LYPXL_bnd PF13949.6 EGO24469.1 - 2.2 7.5 21.3 0.11 11.7 10.4 2.8 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV RasGAP_C PF03836.15 EGO24469.1 - 3 8.0 10.0 37 4.5 0.1 4.0 2 1 2 4 4 4 0 RasGAP C-terminus LysM PF01476.20 EGO24470.1 - 2.2e-06 27.6 0.0 1.8e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 LysM domain NACHT PF05729.12 EGO24472.1 - 1.2e-05 25.3 0.1 2.5e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EGO24472.1 - 0.0051 16.0 0.0 0.0073 15.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EGO24472.1 - 0.008 16.5 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO24472.1 - 0.0089 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AA_permease_N PF08403.10 EGO24472.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal N2227 PF07942.12 EGO24472.1 - 0.051 12.7 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein PEPcase PF00311.17 EGO24472.1 - 0.098 10.7 0.3 0.12 10.5 0.3 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase ResIII PF04851.15 EGO24472.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RuBisCO_small PF00101.20 EGO24473.1 - 0.032 14.2 0.0 0.037 14.0 0.0 1.0 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Aldo_ket_red PF00248.21 EGO24474.1 - 1e-72 244.9 0.0 1.1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acyl-CoA_dh_1 PF00441.24 EGO24475.1 - 3.4e-30 105.2 0.3 4.8e-30 104.8 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO24475.1 - 5.8e-18 64.9 0.6 1.1e-17 64.0 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EGO24475.1 - 7.8e-16 58.0 0.0 1.8e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGO24475.1 - 2.1e-13 50.9 0.0 4.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO24475.1 - 1.9e-05 24.9 0.1 3.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hva1_TUDOR PF11160.8 EGO24476.1 - 7.7e-08 32.4 1.1 3.1e-07 30.4 1.1 1.8 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain BTB PF00651.31 EGO24477.1 - 0.0044 17.2 0.2 0.029 14.6 0.2 2.2 1 1 0 1 1 1 1 BTB/POZ domain MIF4G PF02854.19 EGO24478.1 - 2.5e-24 86.1 2.7 5.4e-24 85.0 2.7 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGO24478.1 - 3.7e-20 72.0 0.0 1.8e-19 69.8 0.0 2.2 1 0 0 1 1 1 1 MA3 domain Pox_P35 PF03213.14 EGO24478.1 - 0.097 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus P35 protein MNNL PF07657.13 EGO24478.1 - 0.1 12.6 1.0 0.26 11.4 1.0 1.6 1 0 0 1 1 1 0 N terminus of Notch ligand Pam16 PF03656.13 EGO24479.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 1 0 1 1 1 0 Pam16 DnaJ PF00226.31 EGO24479.1 - 0.03 14.5 0.1 0.044 13.9 0.1 1.3 1 1 0 1 1 1 0 DnaJ domain AAA_12 PF13087.6 EGO24481.1 - 1.3e-25 90.2 0.3 2.8e-25 89.1 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO24481.1 - 0.00038 20.2 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO24481.1 - 0.0005 20.0 0.0 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGO24481.1 - 0.046 14.1 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGO24482.1 - 2.3e-26 93.2 0.1 4.3e-15 56.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EGO24482.1 - 2.2e-17 63.4 0.0 6.1e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO24482.1 - 1.6e-13 51.2 0.0 1.1e-12 48.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EGO24482.1 - 3.8e-10 39.7 0.0 5.9e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO24482.1 - 5.4e-07 30.2 0.0 8.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 EGO24482.1 - 2.5e-06 27.6 0.0 6.4e-06 26.3 0.0 1.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 EGO24482.1 - 1.5e-05 24.5 0.0 5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 KaiC Helicase_RecD PF05127.14 EGO24482.1 - 4.1e-05 23.5 0.2 0.00046 20.1 0.2 2.2 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.9 EGO24482.1 - 7.2e-05 22.2 0.2 0.068 12.4 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Herpes_ori_bp PF02399.15 EGO24482.1 - 0.00053 18.2 0.0 0.0008 17.6 0.0 1.2 1 0 0 1 1 1 1 Origin of replication binding protein ATPase_2 PF01637.18 EGO24482.1 - 0.00075 19.5 0.0 0.0091 15.9 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGO24482.1 - 0.0011 19.3 0.0 0.0052 17.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain DEAD PF00270.29 EGO24482.1 - 0.0041 16.9 0.0 0.0091 15.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EGO24482.1 - 0.0064 16.0 0.3 0.11 12.0 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Rad17 PF03215.15 EGO24482.1 - 0.0074 16.2 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EGO24482.1 - 0.0086 16.5 0.1 0.028 14.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EGO24482.1 - 0.0092 14.9 0.6 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 EGO24482.1 - 0.0097 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EGO24482.1 - 0.0099 15.6 0.2 0.5 10.1 0.0 2.4 1 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGO24482.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF4265 PF14085.6 EGO24482.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) TniB PF05621.11 EGO24482.1 - 0.017 14.5 0.0 0.44 9.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 EGO24482.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EGO24482.1 - 0.021 13.9 0.1 0.045 12.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 EGO24482.1 - 0.031 14.0 0.2 1.2 8.9 0.0 2.6 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 EGO24482.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGO24482.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 EGO24482.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 EGO24482.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 EGO24482.1 - 0.096 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGO24482.1 - 0.1 12.3 0.2 0.26 11.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EGO24482.1 - 0.14 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_18 PF13238.6 EGO24482.1 - 0.14 12.7 0.0 0.5 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGO24482.1 - 0.15 12.5 0.2 0.55 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGO24482.1 - 0.15 12.2 0.2 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGO24482.1 - 0.16 11.6 0.0 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Carn_acyltransf PF00755.20 EGO24483.1 - 4.4e-171 570.5 0.0 5e-171 570.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DnaJ PF00226.31 EGO24484.1 - 1.4e-14 54.0 0.3 3.8e-14 52.5 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain NGP1NT PF08153.12 EGO24484.1 - 0.062 13.4 0.6 0.062 13.4 0.6 2.3 1 1 1 2 2 2 0 NGP1NT (NUC091) domain CtaG_Cox11 PF04442.14 EGO24485.1 - 6.8e-60 201.5 0.0 9.1e-60 201.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 XPG_N PF00752.17 EGO24486.1 - 1.2e-31 109.1 0.0 1.7e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGO24487.1 - 7.1e-27 93.6 0.0 1.7e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGO24487.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EGO24487.1 - 0.0066 17.0 0.0 0.033 14.8 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold NDUF_B8 PF05821.11 EGO24488.1 - 4.4e-05 23.4 0.8 0.00012 22.0 0.8 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_25 PF13649.6 EGO24489.1 - 8.9e-17 61.6 0.0 2e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO24489.1 - 4.8e-13 49.6 0.0 1.1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO24489.1 - 4.1e-10 39.7 0.0 9.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO24489.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGO24489.1 - 7e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO24489.1 - 7.2e-08 33.1 0.0 1.5e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO24489.1 - 0.0039 16.8 0.0 0.02 14.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EGO24489.1 - 0.0078 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EGO24489.1 - 0.011 15.2 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_29 PF03141.16 EGO24489.1 - 0.02 13.4 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 EGO24489.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 EGO24489.1 - 0.053 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EGO24489.1 - 0.074 12.9 0.0 0.59 9.9 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.20 EGO24489.1 - 0.27 10.5 0.0 0.73 9.1 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_M24 PF00557.24 EGO24490.1 - 3.7e-17 62.7 0.3 4.8e-17 62.3 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Citrate_synt PF00285.21 EGO24492.1 - 1.7e-116 389.3 0.0 2e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain TPR_2 PF07719.17 EGO24493.1 - 1e-09 37.8 8.9 0.0032 17.5 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO24493.1 - 4.4e-07 29.4 9.4 0.00034 20.3 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO24493.1 - 8.6e-07 29.3 0.7 0.54 11.2 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO24493.1 - 5e-06 26.6 1.2 5.1e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGO24493.1 - 3.4e-05 24.2 2.6 0.0012 19.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24493.1 - 0.00034 20.4 0.3 0.22 11.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EGO24493.1 - 0.0013 18.5 9.2 0.0032 17.2 0.6 3.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 DUF5113 PF17140.4 EGO24493.1 - 0.0024 17.7 0.4 0.11 12.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5113) TPR_16 PF13432.6 EGO24493.1 - 0.0049 17.5 0.5 2.3 8.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO24493.1 - 0.0066 16.7 0.2 1.3 9.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO24493.1 - 0.008 16.8 1.7 1.6 9.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 EGO24493.1 - 0.012 15.8 1.7 0.17 12.2 0.1 3.1 3 1 1 4 4 4 0 PPR repeat SMG1 PF15785.5 EGO24493.1 - 0.016 13.6 0.6 0.02 13.3 0.6 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 TPR_12 PF13424.6 EGO24493.1 - 0.017 15.4 3.6 1.8 8.9 0.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat FAT PF02259.23 EGO24493.1 - 0.029 13.6 2.2 0.44 9.7 0.1 2.2 1 1 1 2 2 2 0 FAT domain TPR_11 PF13414.6 EGO24493.1 - 0.17 11.6 3.3 4.6 7.0 0.2 2.9 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 EGO24493.1 - 0.43 10.9 4.3 0.76 10.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Med26 PF08711.11 EGO24496.1 - 6.7e-10 38.8 0.4 5.1e-09 36.0 0.0 2.5 2 0 0 2 2 2 1 TFIIS helical bundle-like domain z-alpha PF02295.17 EGO24497.1 - 0.1 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain zf-CCHC PF00098.23 EGO24498.1 - 1.2e-06 28.3 3.5 3.1e-06 27.0 3.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO24498.1 - 0.00023 21.4 2.3 0.00092 19.4 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 EGO24498.1 - 0.61 9.9 2.7 1.1 9.0 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Peroxidase_ext PF11895.8 EGO24500.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal peroxidase extension region GST_N_4 PF17172.4 EGO24501.1 - 2.1e-25 89.4 0.0 3.4e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGO24501.1 - 2.7e-09 37.4 0.0 3.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGO24501.1 - 6.9e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO24501.1 - 0.001 19.4 0.0 0.0035 17.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO24501.1 - 0.0024 17.8 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO24501.1 - 0.019 15.1 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Memo PF01875.17 EGO24502.1 - 4.5e-73 245.7 0.0 5.2e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein GST_N_4 PF17172.4 EGO24503.1 - 4e-14 53.1 0.0 6.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGO24503.1 - 5.1e-10 39.7 0.0 7.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGO24503.1 - 4.7e-06 26.3 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO24503.1 - 0.025 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.6 EGO24503.1 - 0.15 12.6 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2256 PF10013.9 EGO24503.1 - 1.1 9.4 3.9 2.5 8.3 3.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Actin PF00022.19 EGO24504.1 - 3e-78 263.2 0.0 1.2e-76 258.0 0.0 2.0 1 1 0 1 1 1 1 Actin UPF0061 PF02696.14 EGO24505.1 - 1.9e-100 336.9 0.0 3e-100 336.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Glyco_hydro_79C PF16862.5 EGO24506.1 - 9.2e-18 65.0 0.1 3e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 EGO24506.1 - 0.11 11.4 0.0 0.51 9.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain CoA_transf_3 PF02515.17 EGO24507.1 - 2.4e-58 198.1 0.0 1.2e-57 195.7 0.0 1.8 1 1 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 EGO24509.1 - 6e-32 110.9 0.2 9.3e-32 110.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO24509.1 - 2.6e-20 72.4 0.4 5.4e-20 71.4 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EGO24509.1 - 4.1e-16 58.9 0.0 9.3e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGO24509.1 - 7.5e-15 55.6 0.0 1.7e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO24509.1 - 3.1e-07 30.7 0.1 6.5e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Trp_oprn_chp PF09534.10 EGO24510.1 - 0.00045 20.1 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Alph_Pro_TM PF09608.10 EGO24510.1 - 0.0078 16.1 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) FAM176 PF14851.6 EGO24510.1 - 0.015 15.0 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 FAM176 family Mid2 PF04478.12 EGO24510.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EXOSC1 PF10447.9 EGO24511.1 - 1.5e-15 57.7 2.9 5.1e-11 43.1 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGO24511.1 - 0.0061 16.3 0.2 0.0061 16.3 0.2 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region NAD_binding_10 PF13460.6 EGO24512.1 - 7.4e-10 39.0 0.1 1.1e-09 38.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO24512.1 - 1.3e-08 34.7 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGO24512.1 - 5.6e-08 32.5 0.0 6.6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO24512.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGO24512.1 - 0.0002 21.8 0.1 0.00063 20.2 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EGO24512.1 - 0.00038 19.7 0.0 0.00067 18.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EGO24512.1 - 0.00039 20.7 0.0 0.00072 19.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGO24512.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N PF00107.26 EGO24512.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EGO24513.1 - 1.2e-09 38.3 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO24513.1 - 5.9e-08 32.5 0.0 0.0019 17.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO24513.1 - 7.5e-08 32.2 0.1 1.4e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EGO24513.1 - 3.5e-05 24.2 0.1 7.7e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGO24513.1 - 7.6e-05 21.9 0.0 0.00014 21.0 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EGO24513.1 - 0.00029 21.1 0.1 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGO24513.1 - 0.00051 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EGO24513.1 - 0.00078 18.7 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO24513.1 - 0.0044 16.5 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EGO24513.1 - 0.065 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 EGO24516.1 - 6e-11 42.6 0.2 9.5e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO24516.1 - 1.4e-08 34.5 0.0 0.00025 20.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO24516.1 - 1.9e-08 34.2 0.1 2.8e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EGO24516.1 - 6.8e-07 29.8 0.1 1.6e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGO24516.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGO24516.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_4 PF07993.12 EGO24516.1 - 0.00027 20.2 0.1 0.0014 17.9 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein F420_oxidored PF03807.17 EGO24516.1 - 0.00088 19.8 0.1 0.0021 18.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGO24516.1 - 0.0037 17.3 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EGO24516.1 - 0.0055 16.2 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO24516.1 - 0.007 15.4 0.0 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGO24516.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 EGO24516.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 EGO24517.1 - 7.2e-11 42.3 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO24517.1 - 1.2e-09 38.1 0.1 1.9e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGO24517.1 - 2.8e-09 36.8 0.0 8.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO24517.1 - 5.1e-08 33.4 0.2 1.3e-07 32.1 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGO24517.1 - 9.3e-06 25.9 0.0 2.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGO24517.1 - 8.7e-05 22.6 0.1 0.00027 21.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EGO24517.1 - 0.00051 20.3 0.1 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 EGO24517.1 - 0.00066 20.2 0.1 0.0024 18.4 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EGO24517.1 - 0.0035 16.4 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO24517.1 - 0.022 13.9 0.1 0.049 12.8 0.0 1.7 2 1 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO24517.1 - 0.086 12.2 0.0 7.6 5.8 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EGO24517.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SH3_9 PF14604.6 EGO24519.1 - 0.00011 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO24519.1 - 0.031 13.9 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 SH3 domain SPX PF03105.19 EGO24519.1 - 0.19 11.6 4.2 0.23 11.3 4.2 1.1 1 0 0 1 1 1 0 SPX domain ANAPC4_WD40 PF12894.7 EGO24520.1 - 3.7e-05 23.9 0.1 0.045 14.0 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO24520.1 - 0.00066 20.4 12.8 1.4 9.9 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2370 PF10176.9 EGO24521.1 - 5.6e-29 101.4 0.2 5.9e-29 101.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Rsm1 PF08600.10 EGO24523.1 - 5.8e-13 48.8 0.1 7.3e-10 38.9 0.0 2.9 3 0 0 3 3 3 2 Rsm1-like zf-C3HC PF07967.13 EGO24523.1 - 4.8e-08 33.1 0.0 1.4e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like DUF434 PF04256.12 EGO24523.1 - 0.12 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) DM PF00751.18 EGO24523.1 - 0.36 10.8 6.1 2.5 8.0 0.1 2.6 3 0 0 3 3 3 0 DM DNA binding domain Connexin PF00029.19 EGO24524.1 - 0.31 10.8 1.2 0.43 10.3 1.2 1.2 1 0 0 1 1 1 0 Connexin TFB6 PF17110.5 EGO24524.1 - 0.79 9.4 4.4 1.1 8.9 4.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 EGO24524.1 - 3.9 6.1 4.7 5.3 5.7 4.7 1.1 1 0 0 1 1 1 0 Presenilin PPR_2 PF13041.6 EGO24525.1 - 0.017 15.3 0.6 0.38 11.0 0.0 3.3 4 0 0 4 4 4 0 PPR repeat family Ribosomal_L10 PF00466.20 EGO24527.1 - 5.7e-23 80.9 0.4 2.8e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGO24527.1 - 1.3e-22 79.6 0.0 2.4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGO24527.1 - 9.6e-19 67.8 7.8 9.6e-19 67.8 7.8 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein MMS22L_C PF14911.6 EGO24527.1 - 0.0085 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal Glyco_transf_20 PF00982.21 EGO24529.1 - 4.9e-187 622.3 0.0 4.1e-186 619.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EGO24529.1 - 0.00034 21.0 0.0 0.00073 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGO24529.1 - 0.051 13.1 0.1 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Cation_ATPase_C PF00689.21 EGO24534.1 - 2.3e-47 161.0 4.6 2.3e-47 161.0 4.6 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGO24534.1 - 5e-34 117.4 0.3 5e-34 117.4 0.3 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGO24534.1 - 2.7e-22 78.7 0.0 7e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO24534.1 - 2.9e-15 57.1 1.4 2.3e-14 54.2 1.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO24534.1 - 1e-08 34.7 0.5 8.9e-07 28.5 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO24534.1 - 0.00029 20.7 0.1 0.061 13.0 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SPT_ssu-like PF11779.8 EGO24535.1 - 9.1e-19 66.8 1.5 1.3e-18 66.3 1.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like SAD_SRA PF02182.17 EGO24537.1 - 5.1e-54 182.2 0.1 6.4e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 SAD/SRA domain Serinc PF03348.15 EGO24538.1 - 2e-162 541.0 8.9 2.3e-162 540.8 8.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Rad51 PF08423.11 EGO24539.1 - 3.8e-08 32.9 0.0 9.7e-08 31.6 0.0 1.6 1 1 1 2 2 2 1 Rad51 ATPase PF06745.13 EGO24539.1 - 0.03 13.7 0.0 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 EGO24539.1 - 0.034 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF1805 PF08827.11 EGO24539.1 - 0.071 13.5 0.4 4.5 7.7 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1805) Caleosin PF05042.13 EGO24541.1 - 1.3e-68 230.3 0.1 1.5e-68 230.0 0.1 1.0 1 0 0 1 1 1 1 Caleosin related protein Maf1 PF09174.10 EGO24542.1 - 1.3e-40 139.4 0.2 1.1e-33 116.9 0.0 2.4 2 0 0 2 2 2 2 Maf1 regulator SCP2 PF02036.17 EGO24543.1 - 2.6e-23 82.4 0.3 3.6e-23 82.0 0.3 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGO24543.1 - 0.00097 19.4 0.1 0.0013 19.0 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Dynamin_N PF00350.23 EGO24544.1 - 8.1e-43 146.4 0.0 2.2e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EGO24544.1 - 9.3e-10 38.2 0.0 1.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EGO24544.1 - 5.6e-05 23.2 0.0 0.00018 21.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGO24544.1 - 0.035 13.9 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGO24544.1 - 0.063 13.0 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain DHDPS PF00701.22 EGO24545.1 - 2.5e-41 141.3 0.0 3e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sipho_Gp37 PF14594.6 EGO24545.1 - 0.16 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein KASH_CCD PF14662.6 EGO24546.1 - 0.0068 16.2 2.5 0.011 15.6 2.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH p450 PF00067.22 EGO24547.1 - 3.2e-63 214.1 0.0 3.9e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO24548.1 - 2.6e-69 234.2 0.0 3.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_9 PF00759.19 EGO24548.1 - 0.063 12.7 0.8 0.093 12.1 0.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Glyco_transf_41 PF13844.6 EGO24549.1 - 2.3e-75 253.8 5.3 1.1e-46 159.3 0.2 3.6 3 1 0 3 3 3 3 Glycosyl transferase family 41 TPR_8 PF13181.6 EGO24549.1 - 5.3e-09 35.6 0.0 0.12 12.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO24549.1 - 8.1e-09 34.9 1.0 0.0074 16.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO24549.1 - 9.7e-07 28.8 0.0 0.09 13.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO24549.1 - 4.5e-06 26.4 0.0 1.1 9.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO24549.1 - 4.1e-05 24.0 1.3 0.012 16.1 0.1 2.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO24549.1 - 0.00025 20.8 0.6 0.26 11.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO24549.1 - 0.00032 20.9 0.0 0.0023 18.2 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24549.1 - 0.00077 19.3 0.0 0.39 10.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO24549.1 - 0.00086 19.9 0.0 0.21 12.5 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO24549.1 - 0.0019 17.8 0.1 0.081 12.6 0.0 2.7 1 1 1 2 2 2 1 TPR repeat TPR_6 PF13174.6 EGO24549.1 - 0.01 16.4 0.0 2 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO24549.1 - 0.051 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4388 PF14332.6 EGO24549.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) TPR_16 PF13432.6 EGO24549.1 - 0.11 13.1 0.0 0.32 11.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO24550.1 - 2.8e-30 101.9 10.4 2.9e-06 26.9 0.1 9.6 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGO24550.1 - 4.1e-27 92.9 3.0 6e-09 35.3 0.0 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO24550.1 - 5e-25 87.5 3.9 6.2e-10 39.2 0.0 6.5 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGO24550.1 - 1e-19 69.0 0.1 9.5e-07 28.6 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO24550.1 - 1.8e-19 69.8 18.5 2.4e-11 43.8 0.1 8.1 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO24550.1 - 2.1e-18 66.6 1.3 4e-05 24.0 0.0 7.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO24550.1 - 2.1e-17 63.5 3.1 4.8e-08 33.5 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24550.1 - 4.1e-16 57.8 7.3 0.00046 20.0 0.0 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO24550.1 - 4.7e-10 39.1 0.2 2.8 8.5 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGO24550.1 - 4e-09 36.5 19.3 0.001 19.6 0.1 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO24550.1 - 1.3e-08 35.0 12.2 0.12 13.3 0.0 8.7 6 2 4 10 10 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO24550.1 - 3.2e-08 33.1 0.2 0.013 15.2 0.0 5.8 5 1 1 6 6 6 2 TPR repeat TPR_10 PF13374.6 EGO24550.1 - 1.1e-07 31.5 10.0 0.0022 17.8 0.1 6.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO24550.1 - 6.1e-07 29.5 6.3 0.0011 19.1 0.1 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO24550.1 - 1.9e-05 24.3 3.3 0.019 14.3 0.2 3.9 3 1 2 5 5 5 2 MalT-like TPR region Fis1_TPR_C PF14853.6 EGO24550.1 - 4.4e-05 23.5 1.5 0.0039 17.2 0.1 4.2 5 0 0 5 5 3 1 Fis1 C-terminal tetratricopeptide repeat Paf67 PF10255.9 EGO24550.1 - 0.013 14.5 0.0 0.14 11.1 0.0 2.6 4 0 0 4 4 4 0 RNA polymerase I-associated factor PAF67 TPR_15 PF13429.6 EGO24550.1 - 0.025 13.8 3.6 0.48 9.6 0.1 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 EGO24550.1 - 0.04 13.3 0.3 2.2 7.7 0.3 2.9 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 EGO24550.1 - 0.11 11.9 0.2 2 7.8 0.0 2.9 3 1 1 4 4 4 0 Coatomer epsilon subunit HemY_N PF07219.13 EGO24550.1 - 0.13 12.5 0.0 29 4.9 0.0 3.2 3 0 0 3 3 3 0 HemY protein N-terminus TPR_3 PF07720.12 EGO24550.1 - 0.25 11.4 6.2 12 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGO24550.1 - 0.36 11.6 4.8 16 6.5 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 EGO24552.1 - 1.1e-16 60.4 0.0 2.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO24552.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO24552.1 - 0.033 14.3 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Sugar_tr PF00083.24 EGO24553.1 - 2.6e-50 171.6 22.6 3.7e-50 171.1 22.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO24553.1 - 5.1e-19 68.4 32.1 6.1e-15 55.0 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.15 EGO24554.1 - 4.5e-10 39.4 0.2 4.5e-10 39.4 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO24554.1 - 0.0012 19.5 0.9 0.0017 19.1 0.9 1.3 1 1 0 1 1 1 1 Complex1_LYR-like eIF-1a PF01176.19 EGO24555.1 - 3.1e-23 81.4 0.1 4.5e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ank_2 PF12796.7 EGO24556.1 - 2.2e-06 28.2 0.0 0.001 19.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO24556.1 - 0.00064 20.0 0.2 1.4 9.7 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EGO24556.1 - 0.00098 19.4 0.1 6 7.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO24556.1 - 0.016 15.7 0.1 0.053 14.1 0.1 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Macro PF01661.21 EGO24557.1 - 6.4e-42 142.3 0.1 8.7e-42 141.9 0.1 1.2 1 0 0 1 1 1 1 Macro domain Pkinase PF00069.25 EGO24558.1 - 1.6e-63 214.5 0.0 2.4e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO24558.1 - 1.7e-36 125.8 0.0 2.5e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO24558.1 - 5.6e-09 35.7 0.0 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO24558.1 - 0.00025 19.9 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO24558.1 - 0.00082 19.4 0.5 0.0014 18.6 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO24558.1 - 0.0024 16.9 0.2 0.0044 16.0 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO24558.1 - 0.0079 15.6 0.4 0.017 14.5 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO24558.1 - 0.075 12.6 0.9 6.1 6.4 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SHP PF03579.13 EGO24559.1 - 0.067 13.2 0.7 0.16 12.0 0.7 1.6 1 0 0 1 1 1 0 Small hydrophobic protein Ion_trans PF00520.31 EGO24559.1 - 1.6 7.9 18.0 4.5 6.4 11.8 2.3 1 1 1 2 2 2 0 Ion transport protein MBOAT_2 PF13813.6 EGO24561.1 - 1.3e-18 67.0 2.5 4.5e-18 65.3 2.5 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 EGO24562.1 - 7.8e-15 54.9 5.4 5.6e-14 52.2 4.3 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Phage_holin_2_3 PF16080.5 EGO24562.1 - 0.27 11.0 7.8 2.9 7.7 0.1 3.2 3 1 0 3 3 3 0 Bacteriophage holin family HP1 WD40 PF00400.32 EGO24563.1 - 0.054 14.4 0.1 1.1 10.3 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat PPP4R2 PF09184.11 EGO24563.1 - 0.21 11.2 5.3 0.42 10.1 5.3 1.5 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EGO24563.1 - 1.4 7.1 6.6 2.2 6.4 6.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGO24563.1 - 1.6 6.9 5.2 2.6 6.2 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EGO24563.1 - 7.4 6.2 8.7 1.3 8.7 3.5 2.1 2 0 0 2 2 2 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 EGO24563.1 - 9.6 6.4 20.9 1.2 9.3 12.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CBS PF00571.28 EGO24564.1 - 6e-25 87.5 3.0 2.3e-10 40.8 0.1 4.8 4 1 1 5 5 5 4 CBS domain DUF4704 PF15787.5 EGO24564.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Epimerase PF01370.21 EGO24566.1 - 2e-21 76.5 0.0 2.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO24566.1 - 6.7e-14 52.0 0.0 2.7e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO24566.1 - 2.1e-10 40.8 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO24566.1 - 7e-10 38.4 0.0 9.6e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO24566.1 - 0.0001 21.5 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGO24566.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EGO24566.1 - 0.0053 16.9 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NPR3 PF03666.13 EGO24567.1 - 5.4e-104 348.6 1.7 5.2e-101 338.7 1.7 2.3 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Hydrolase_4 PF12146.8 EGO24568.1 - 1.7e-06 27.5 0.0 1.5e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO24568.1 - 2.9e-06 27.1 0.0 5.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO24568.1 - 1.2e-05 26.0 0.0 0.00021 22.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGO24568.1 - 7.7e-05 22.4 0.1 0.00035 20.3 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.14 EGO24568.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Cutinase PF01083.22 EGO24568.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Cutinase VirJ PF06057.11 EGO24568.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) SAD_SRA PF02182.17 EGO24569.1 - 1.5e-23 83.2 0.4 1.9e-23 82.9 0.4 1.1 1 0 0 1 1 1 1 SAD/SRA domain Acetyltransf_3 PF13302.7 EGO24570.1 - 4.8e-23 82.4 0.0 5.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGO24570.1 - 4.2e-08 33.0 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO24570.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ARID PF01388.21 EGO24571.1 - 1.1e-07 32.4 0.0 3.4e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Exo_endo_phos PF03372.23 EGO24571.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF572 PF04502.13 EGO24573.1 - 3e-66 224.3 4.4 3.5e-66 224.1 4.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) IBB PF01749.20 EGO24573.1 - 0.0035 17.7 4.6 0.0087 16.5 4.6 1.7 1 0 0 1 1 1 1 Importin beta binding domain Ribosomal_S10 PF00338.22 EGO24574.1 - 3.2e-28 97.8 0.5 3.7e-28 97.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SNARE_assoc PF09335.11 EGO24575.1 - 3e-10 40.6 4.7 3e-10 40.6 4.7 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein TFIIE-A_C PF11521.8 EGO24575.1 - 0.085 13.2 2.8 0.17 12.2 2.8 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DnaJ PF00226.31 EGO24577.1 - 1.1e-17 63.9 0.0 3e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.19 EGO24578.1 - 1e-40 139.2 0.0 1.4e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGO24578.1 - 0.0025 17.7 0.0 0.007 16.3 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain DUF1574 PF07611.11 EGO24578.1 - 0.0081 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) MobB PF03205.14 EGO24578.1 - 0.011 15.6 0.2 0.064 13.1 0.0 2.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4858 PF16150.5 EGO24578.1 - 0.042 13.9 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) AAA_16 PF13191.6 EGO24578.1 - 0.071 13.5 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Frag1 PF10277.9 EGO24579.1 - 4.6e-25 88.4 11.5 2.7e-24 86.0 11.5 2.4 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Adaptin_N PF01602.20 EGO24580.1 - 6e-123 411.2 4.0 9.3e-123 410.5 4.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO24580.1 - 1.3e-14 54.6 5.6 1.6e-12 47.8 0.1 4.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO24580.1 - 2.4e-08 34.2 1.7 0.0018 18.6 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGO24580.1 - 0.00016 21.7 1.7 2.8 8.4 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Cohesin_HEAT PF12765.7 EGO24580.1 - 0.0035 17.6 0.5 3.2 8.1 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 EGO24580.1 - 0.084 13.4 2.2 46 4.7 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat COX6B PF02297.17 EGO24581.1 - 1.3e-15 57.3 2.7 1.9e-15 56.8 2.7 1.3 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EGO24581.1 - 0.022 14.8 2.1 0.022 14.8 2.1 1.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Peptidase_C107 PF17222.3 EGO24581.1 - 0.053 12.5 0.0 0.056 12.4 0.0 1.0 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 Prp18 PF02840.15 EGO24582.1 - 2.3e-61 206.1 0.1 2.3e-61 206.1 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EGO24582.1 - 3.4e-11 42.5 6.4 7.6e-11 41.4 6.4 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Macoilin PF09726.9 EGO24582.1 - 0.4 9.2 5.3 0.65 8.5 5.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF2058 PF09831.9 EGO24582.1 - 0.46 10.6 7.3 0.096 12.8 3.5 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) zf-C2H2_jaz PF12171.8 EGO24583.1 - 1.3e-10 41.2 0.2 1.9e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO24583.1 - 1.4e-09 38.0 0.5 2e-09 37.5 0.5 1.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGO24583.1 - 0.003 17.9 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EGO24583.1 - 0.011 15.7 0.4 0.016 15.2 0.4 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGO24583.1 - 0.026 15.3 0.1 0.039 14.8 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO24583.1 - 0.062 13.8 0.1 0.085 13.4 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-Tim10_DDP PF02953.15 EGO24584.1 - 1.4e-24 85.5 3.7 1.9e-24 85.1 3.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EGO24584.1 - 0.0099 15.6 1.8 0.014 15.1 1.8 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Cytomega_TRL10 PF06084.11 EGO24584.1 - 0.064 13.3 1.5 0.077 13.0 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Homeodomain PF00046.29 EGO24585.1 - 6.7e-18 64.3 2.4 1.1e-17 63.6 2.4 1.4 1 0 0 1 1 1 1 Homeodomain DUF4663 PF15668.5 EGO24585.1 - 2.1 7.3 5.1 3.6 6.5 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) UbiA PF01040.18 EGO24586.1 - 8.7e-59 198.8 14.9 1.3e-58 198.3 14.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_hydro_79C PF16862.5 EGO24587.1 - 6.5e-17 62.3 0.0 1.4e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain NAPRTase PF04095.16 EGO24588.1 - 1.5e-58 198.2 0.1 2.3e-58 197.7 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EGO24588.1 - 2.3e-37 128.2 0.1 3.6e-37 127.5 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain YARHG PF13308.6 EGO24588.1 - 0.051 13.5 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 YARHG domain Citrate_synt PF00285.21 EGO24589.1 - 6.7e-99 331.4 0.0 8e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EGO24589.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone ANAPC4_WD40 PF12894.7 EGO24591.1 - 0.0036 17.6 0.1 0.012 15.9 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO24591.1 - 0.0082 17.0 0.2 0.13 13.2 0.0 3.0 3 1 0 3 3 3 1 WD domain, G-beta repeat TRAP-gamma PF07074.12 EGO24591.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) P34-Arc PF04045.14 EGO24593.1 - 1.7e-112 374.9 0.7 2.1e-112 374.6 0.7 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RRM_1 PF00076.22 EGO24594.1 - 1e-13 50.9 0.0 1.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 EGO24595.1 - 7.4e-44 149.8 0.0 8.7e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 EGO24596.1 - 4.2e-46 156.5 0.0 4.9e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO24596.1 - 4.1e-17 62.5 0.0 5.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGO24596.1 - 3.9e-07 30.1 0.0 0.00086 19.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EGO24596.1 - 8.2e-05 22.1 0.0 9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO24596.1 - 0.00049 20.2 0.0 0.00085 19.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGO24596.1 - 0.025 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO24596.1 - 0.14 12.6 0.4 0.26 11.7 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGO24596.1 - 0.14 11.4 0.1 0.77 9.0 0.0 2.0 2 1 0 2 2 2 0 Septin DEAD PF00270.29 EGO24597.1 - 5.3e-52 176.1 0.0 6.4e-51 172.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO24597.1 - 3.4e-32 111.1 0.0 1.2e-30 106.1 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO24597.1 - 6e-08 32.9 0.0 2.2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EGO24597.1 - 0.042 12.6 0.0 0.37 9.5 0.0 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2313 PF10076.9 EGO24597.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) GRP PF07172.11 EGO24597.1 - 1.2 9.8 24.6 2.9 8.7 24.6 1.6 1 0 0 1 1 1 0 Glycine rich protein family Retrotrans_gag PF03732.17 EGO24598.1 - 1.9e-05 24.8 2.7 4e-05 23.8 0.9 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO24598.1 - 4.5e-05 23.3 2.6 4.5e-05 23.3 2.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO24598.1 - 0.039 13.9 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle Hydrophobin_2 PF06766.11 EGO24598.1 - 0.099 12.6 0.6 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Fungal hydrophobin YL1 PF05764.13 EGO24599.1 - 0.00066 19.9 11.3 0.00066 19.9 11.3 1.4 2 0 0 2 2 2 1 YL1 nuclear protein DUF2040 PF09745.9 EGO24599.1 - 0.0029 17.6 4.5 0.0029 17.6 4.5 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) BUD22 PF09073.10 EGO24599.1 - 0.0033 16.8 10.4 0.0046 16.4 10.4 1.2 1 0 0 1 1 1 1 BUD22 SR-25 PF10500.9 EGO24599.1 - 0.0034 17.0 9.1 0.0057 16.3 9.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SGT1 PF07093.11 EGO24599.1 - 0.0093 14.5 4.2 0.0091 14.5 4.2 1.2 1 0 0 1 1 1 1 SGT1 protein Cwf_Cwc_15 PF04889.12 EGO24599.1 - 0.059 13.1 14.1 0.11 12.2 14.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4636 PF15468.6 EGO24599.1 - 0.14 11.9 5.5 0.26 11.0 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) CCDC106 PF15794.5 EGO24599.1 - 0.36 10.5 8.1 0.63 9.7 8.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pes-10 PF07149.11 EGO24599.1 - 0.53 9.3 8.0 0.76 8.8 8.0 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 EGO24599.1 - 0.64 8.2 11.8 0.87 7.8 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EGO24599.1 - 2.8 5.9 14.3 4.1 5.4 14.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi YqfQ PF14181.6 EGO24599.1 - 10 6.3 8.7 16 5.6 8.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein Retrotran_gag_2 PF14223.6 EGO24600.1 - 5e-10 39.2 0.1 6.3e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO24600.1 - 6.5e-05 22.5 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO24600.1 - 0.0017 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EGO24604.1 - 0.00076 19.5 1.0 0.0013 18.7 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO24604.1 - 0.061 13.1 0.5 0.1 12.3 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO24606.1 - 6.3e-07 29.6 3.4 8.6e-07 29.2 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein UBX PF00789.20 EGO24607.1 - 7.6e-13 48.5 0.4 1.6e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 UBX domain ThiF PF00899.21 EGO24608.1 - 4.5e-61 206.3 0.0 7.8e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGO24608.1 - 2.8e-09 37.5 0.0 1.5e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EGO24608.1 - 0.00036 20.6 0.3 0.0015 18.6 0.3 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EGO24608.1 - 0.063 12.5 0.1 0.091 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EGO24608.1 - 0.077 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EGO24608.1 - 0.092 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ANAPC10 PF03256.16 EGO24609.1 - 6e-49 166.2 0.0 7.2e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EGO24609.1 - 8.5e-05 22.7 0.0 0.00027 21.1 0.0 1.8 1 1 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 EGO24609.1 - 0.18 12.0 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 PITH domain PHD PF00628.29 EGO24610.1 - 5.2e-07 29.5 12.2 9.5e-07 28.6 12.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGO24610.1 - 0.0033 17.6 2.1 0.0072 16.6 2.1 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain WSD PF15613.6 EGO24610.1 - 0.19 12.2 4.5 0.37 11.3 0.0 2.9 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif YaaC PF14175.6 EGO24610.1 - 0.67 9.1 4.0 1 8.6 2.4 2.0 2 0 0 2 2 2 0 YaaC-like Protein Alba PF01918.21 EGO24611.1 - 2.4e-06 27.2 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 Alba PITH PF06201.13 EGO24612.1 - 3.8e-36 124.6 0.0 4.9e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain YchF-GTPase_C PF06071.13 EGO24615.1 - 9.3e-35 118.7 0.0 3.4e-34 116.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGO24615.1 - 1.9e-18 66.6 0.0 6.2e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO24615.1 - 5.4e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RPAP1_N PF08621.10 EGO24615.1 - 0.15 11.8 2.0 0.31 10.9 2.0 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal FliJ PF02050.16 EGO24617.1 - 0.00081 19.6 10.7 0.011 16.0 0.5 2.4 2 0 0 2 2 2 2 Flagellar FliJ protein NPV_P10 PF05531.12 EGO24617.1 - 0.0057 17.1 4.2 0.51 10.8 0.7 2.9 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EGO24617.1 - 0.021 14.9 6.2 0.41 10.7 0.4 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) AKNA PF12443.8 EGO24617.1 - 0.35 11.5 3.6 3.6 8.3 0.4 2.8 2 1 0 3 3 3 0 AT-hook-containing transcription factor FapA PF03961.13 EGO24617.1 - 0.42 9.2 7.6 3.7 6.1 0.3 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A DASH_Duo1 PF08651.10 EGO24617.1 - 0.69 9.7 3.6 14 5.6 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Duo1 End3 PF12761.7 EGO24617.1 - 2 8.5 15.9 0.48 10.6 8.0 2.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Occludin_ELL PF07303.13 EGO24617.1 - 2.2 9.0 8.9 7.9 7.3 0.4 3.6 4 0 0 4 4 4 0 Occludin homology domain Spc7 PF08317.11 EGO24617.1 - 3.8 6.3 11.8 5.1 5.9 0.3 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 EGO24617.1 - 5.5 7.7 13.7 16 6.2 0.7 3.6 4 0 0 4 4 4 0 SlyX LPP PF04728.13 EGO24617.1 - 7 7.1 7.4 42 4.6 0.3 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 EGO24617.1 - 7 6.7 13.5 15 5.6 5.8 3.7 3 1 0 3 3 3 0 Prefoldin subunit Voldacs PF03517.13 EGO24618.1 - 3e-28 98.7 0.3 3e-28 98.7 0.3 1.8 1 1 1 2 2 2 1 Regulator of volume decrease after cellular swelling SH3_1 PF00018.28 EGO24619.1 - 3e-09 36.3 0.1 4.3e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO24619.1 - 7.3e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO24619.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Mito_fiss_reg PF05308.11 EGO24621.1 - 0.18 11.8 3.5 0.2 11.7 3.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MARVEL PF01284.23 EGO24622.1 - 9.4e-11 41.9 12.4 1.4e-10 41.3 12.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF5472 PF17566.2 EGO24622.1 - 2.8 8.0 4.2 0.63 10.0 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5472) NUDIX PF00293.28 EGO24623.1 - 1.6e-10 41.1 0.0 2.5e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Bap31_Bap29_C PF18035.1 EGO24624.1 - 0.54 10.3 5.9 0.076 13.0 1.8 1.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain APG6_N PF17675.1 EGO24624.1 - 4.5 7.8 14.7 0.48 10.9 10.0 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Aminotran_3 PF00202.21 EGO24625.1 - 6.5e-42 143.6 0.0 9.9e-20 70.6 0.1 3.1 1 1 1 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EGO24625.1 - 2.8e-16 59.9 0.0 5.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DAGK_cat PF00781.24 EGO24625.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PI3Ka PF00613.20 EGO24626.1 - 5.5e-54 182.4 0.1 9.2e-54 181.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGO24626.1 - 1.6e-40 139.5 0.0 1.5e-25 90.5 0.0 3.0 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGO24626.1 - 4.7e-39 133.5 0.0 8.4e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 IlvN PF07991.12 EGO24627.1 - 1.1e-45 155.2 0.0 2e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGO24627.1 - 7.4e-39 133.3 0.0 1.2e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF3307 PF11750.8 EGO24628.1 - 0.39 10.8 8.2 1 9.4 8.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3307) Cauli_VI PF01693.16 EGO24629.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Alpha_kinase PF02816.18 EGO24631.1 - 8e-18 65.2 0.0 9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family p450 PF00067.22 EGO24632.1 - 4.3e-07 29.0 0.0 5.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_5 PF13712.6 EGO24632.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family p450 PF00067.22 EGO24634.1 - 4.6e-73 246.5 0.0 5.2e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2205 PF10224.9 EGO24635.1 - 0.55 10.3 5.3 0.36 10.8 0.2 2.5 2 0 0 2 2 2 0 Short coiled-coil protein p450 PF00067.22 EGO24638.1 - 5.9e-60 203.3 0.0 7.3e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aconitase PF00330.20 EGO24639.1 - 1.2e-109 367.3 0.0 1.2e-108 364.0 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO24639.1 - 8.3e-21 74.7 0.0 1.8e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EGO24639.1 - 0.04 12.6 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Sde2_N_Ubi PF13019.6 EGO24640.1 - 1.6e-52 177.6 0.1 7.3e-52 175.5 0.0 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF1295 PF06966.12 EGO24641.1 - 1.3e-35 123.0 3.4 6.9e-35 120.7 3.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) p450 PF00067.22 EGO24642.1 - 2.5e-46 158.4 0.0 2.5e-31 108.9 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 HSP20 PF00011.21 EGO24643.1 - 1.2e-23 83.2 0.1 1.4e-22 79.7 0.0 1.9 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO24643.1 - 1.3e-11 43.9 0.0 1.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EGO24643.1 - 0.082 13.9 0.0 0.11 13.5 0.0 1.3 1 0 0 1 1 1 0 CS domain BON PF04972.17 EGO24643.1 - 0.091 13.1 0.0 2.5 8.5 0.0 2.1 2 0 0 2 2 2 0 BON domain DUF4097 PF13349.6 EGO24643.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 Putative adhesin Imm74 PF15603.6 EGO24643.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 2 0 0 2 2 2 0 Immunity protein 74 p450 PF00067.22 EGO24644.1 - 1.3e-18 67.1 0.0 1.5e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PrlF_antitoxin PF15937.5 EGO24644.1 - 0.17 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin p450 PF00067.22 EGO24645.1 - 1.3e-47 162.6 0.0 1.6e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEC1 PF15859.5 EGO24645.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family CIA30 PF08547.12 EGO24646.1 - 0.036 14.1 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Ras PF00071.22 EGO24647.1 - 1.5e-57 193.7 0.0 1.7e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO24647.1 - 2.1e-20 73.1 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO24647.1 - 1.5e-06 27.8 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGO24647.1 - 0.00038 20.4 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGO24647.1 - 0.0073 15.9 0.0 0.02 14.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGO24647.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGO24647.1 - 0.033 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.22 EGO24648.1 - 1.3e-58 197.2 0.2 1.5e-58 197.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO24648.1 - 2e-20 73.2 0.0 3.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO24648.1 - 8.7e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO24648.1 - 6.2e-06 25.9 0.1 1.2e-05 24.9 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO24648.1 - 3.4e-05 23.8 0.0 0.072 13.0 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO24648.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO24648.1 - 0.029 13.9 0.1 0.082 12.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Ser_hydrolase PF06821.13 EGO24648.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.17 EGO24648.1 - 0.1 12.4 2.3 0.64 9.7 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Tis11B_N PF04553.12 EGO24649.1 - 0.11 13.0 1.1 0.23 12.0 1.1 1.5 1 0 0 1 1 1 0 Tis11B like protein, N terminus IMS PF00817.20 EGO24650.1 - 9.2e-42 142.6 0.0 1.8e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGO24650.1 - 1.8e-16 60.9 0.0 5e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EGO24650.1 - 2.9e-08 33.1 0.5 0.00016 21.2 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EGO24650.1 - 0.00061 20.0 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif PH PF00169.29 EGO24651.1 - 0.0049 17.4 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4596 PF15363.6 EGO24651.1 - 2.4 8.4 0.0 2.4 8.4 0.0 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Pyr_redox_2 PF07992.14 EGO24652.1 - 3.5e-51 174.2 3.0 4.3e-51 173.9 3.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGO24652.1 - 9.8e-18 63.9 0.1 2.3e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EGO24652.1 - 6.4e-10 39.5 5.0 2.3e-09 37.7 0.6 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO24652.1 - 1.2e-09 37.8 0.4 2.8e-09 36.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EGO24652.1 - 5.7e-08 33.2 0.0 1.6e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 EGO24652.1 - 7.3e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 EGO24652.1 - 0.0022 17.2 0.0 0.32 10.1 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EGO24652.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Metallophos PF00149.28 EGO24653.1 - 1.2e-08 35.7 2.0 2.6e-08 34.6 2.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO24653.1 - 1.2e-06 28.9 0.2 2.5e-05 24.5 0.2 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThuA PF06283.11 EGO24655.1 - 1.3e-62 211.7 0.2 1.6e-62 211.4 0.2 1.1 1 0 0 1 1 1 1 Trehalose utilisation DnaJ_C PF01556.18 EGO24656.1 - 1.4e-36 125.8 0.2 1.8e-36 125.4 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO24656.1 - 1.9e-22 79.1 0.7 3.2e-22 78.4 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO24656.1 - 5.6e-12 45.9 18.7 9.7e-12 45.1 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGO24656.1 - 0.0049 16.8 10.6 0.42 10.6 1.8 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGO24656.1 - 1.2 9.2 13.2 4.7 7.3 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Methyltr_RsmB-F PF01189.17 EGO24657.1 - 9.3e-28 97.2 0.0 1.7e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Cons_hypoth95 PF03602.15 EGO24657.1 - 0.0096 15.6 0.3 0.037 13.7 0.0 2.1 2 1 1 3 3 3 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EGO24657.1 - 0.067 13.0 0.0 0.7 9.7 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain SF1-HH PF16275.5 EGO24658.1 - 7.9e-40 135.7 1.3 1.8e-39 134.5 1.3 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EGO24658.1 - 1.1e-11 44.3 8.3 1.5e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EGO24658.1 - 1.5e-06 28.1 4.0 0.0042 17.0 1.6 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EGO24658.1 - 6.2e-06 25.9 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 EGO24658.1 - 0.0014 18.5 4.7 0.42 10.5 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGO24658.1 - 0.0032 17.2 6.7 0.27 11.0 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 EGO24658.1 - 0.0082 16.5 2.4 3.4 8.1 0.1 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 Prim_Zn_Ribbon PF08273.12 EGO24658.1 - 0.2 11.9 3.2 0.48 10.7 3.2 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DnaJ_CXXCXGXG PF00684.19 EGO24658.1 - 0.31 11.4 4.3 0.68 10.3 4.3 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 EGO24658.1 - 2.8 7.7 5.4 0.38 10.5 0.2 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EGO24658.1 - 3.6 7.5 9.3 0.37 10.7 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle ERCC3_RAD25_C PF16203.5 EGO24659.1 - 2.1e-105 351.4 1.0 1.4e-57 194.8 0.1 2.5 1 1 1 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGO24659.1 - 4.9e-34 117.2 0.0 1.2e-33 116.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO24659.1 - 1.7e-16 60.7 0.0 3.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGO24659.1 - 1.1e-09 37.5 0.0 1.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGO24659.1 - 4.6e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO24659.1 - 0.006 16.9 0.1 0.14 12.5 0.0 2.6 1 1 1 2 2 2 1 Helicase conserved C-terminal domain SBP_bac_6 PF13343.6 EGO24659.1 - 0.15 11.4 0.0 0.57 9.6 0.0 1.9 3 0 0 3 3 3 0 Bacterial extracellular solute-binding protein bZIP_1 PF00170.21 EGO24660.1 - 0.0036 17.3 4.4 0.0067 16.5 4.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO24660.1 - 0.018 15.1 2.0 0.037 14.1 2.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper BMFP PF04380.13 EGO24660.1 - 4.2 7.9 5.5 3.6 8.1 3.5 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity UDG PF03167.19 EGO24661.1 - 8e-18 64.9 0.0 3.4e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Response_reg PF00072.24 EGO24662.1 - 9.3e-20 70.9 0.0 2e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGO24662.1 - 1.7e-19 70.4 0.3 4.8e-19 68.9 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGO24662.1 - 2e-12 47.0 0.1 5.5e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EGO24662.1 - 1.4e-06 28.9 0.0 0.0025 18.4 0.0 3.2 2 1 0 2 2 2 2 GAF domain ATPase_gene1 PF09527.10 EGO24662.1 - 0.35 11.1 8.0 1.4 9.1 8.0 2.1 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter HMGL-like PF00682.19 EGO24663.1 - 3.3e-79 266.2 0.3 4.7e-79 265.7 0.3 1.2 1 0 0 1 1 1 1 HMGL-like zf-HIT PF04438.16 EGO24664.1 - 6.9e-08 32.2 10.4 1.3e-07 31.4 10.4 1.4 1 0 0 1 1 1 1 HIT zinc finger Cys_Met_Meta_PP PF01053.20 EGO24665.1 - 8.1e-127 422.9 0.0 1e-126 422.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 EGO24665.1 - 1.7e-15 57.0 0.0 1.7e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO24665.1 - 1.8e-05 25.0 0.0 5.2e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DegT_DnrJ_EryC1 PF01041.17 EGO24665.1 - 0.00024 20.5 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GalKase_gal_bdg PF10509.9 EGO24665.1 - 0.00085 18.8 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.21 EGO24665.1 - 0.0016 17.7 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EGO24665.1 - 0.0093 14.5 0.0 0.024 13.1 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EGO24665.1 - 0.047 13.0 0.0 0.099 11.9 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Terpene_synth_C PF03936.16 EGO24666.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.19 EGO24667.1 - 3.3e-33 113.4 0.2 6.5e-33 112.4 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGO24667.1 - 4.5e-29 100.9 0.0 8.4e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EGO24667.1 - 0.00047 20.2 0.0 0.00074 19.5 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease R3H PF01424.22 EGO24667.1 - 0.097 12.7 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 R3H domain WD40 PF00400.32 EGO24668.1 - 3.4e-10 40.3 1.4 0.11 13.4 0.1 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO24668.1 - 0.0038 17.5 0.0 0.24 11.7 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO24668.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region ECH_1 PF00378.20 EGO24669.1 - 6.7e-20 71.5 0.0 8.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO24669.1 - 0.00014 21.5 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TRAP_alpha PF03896.16 EGO24670.1 - 2e-05 23.9 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.11 EGO24670.1 - 0.0017 17.8 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) Urease_beta PF00699.20 EGO24670.1 - 0.0042 17.1 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Urease beta subunit Sec16_C PF12931.7 EGO24671.1 - 0.049 13.3 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Pkinase PF00069.25 EGO24673.1 - 3.2e-49 167.7 0.0 5.6e-49 166.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO24673.1 - 7.1e-19 68.1 0.0 1.9e-18 66.7 0.0 1.6 2 1 0 2 2 2 1 Protein tyrosine kinase MOZ_SAS PF01853.18 EGO24675.1 - 2.3e-72 242.4 0.0 3.3e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGO24675.1 - 8.5e-21 73.3 0.3 2.1e-20 72.1 0.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 EGO24675.1 - 2.7e-07 30.4 10.4 6.8e-07 29.1 7.1 2.4 2 0 0 2 2 2 1 PHD-finger zf-Sec23_Sec24 PF04810.15 EGO24675.1 - 0.091 12.8 0.8 0.61 10.2 0.1 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.6 EGO24675.1 - 2.7 8.4 8.1 0.55 10.6 2.8 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar CPSF100_C PF13299.6 EGO24675.1 - 3.2 7.9 10.7 0.42 10.8 3.2 2.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RRN3 PF05327.11 EGO24675.1 - 3.5 6.1 10.6 0.014 14.0 1.6 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 p450 PF00067.22 EGO24676.1 - 2.3e-69 234.4 0.0 6.5e-69 232.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DPM3 PF08285.11 EGO24676.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Asp_protease_2 PF13650.6 EGO24677.1 - 0.00044 20.8 0.0 0.00058 20.5 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO24677.1 - 0.00047 20.6 0.0 0.00089 19.8 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO24677.1 - 0.0058 16.4 0.0 0.14 12.0 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EGO24678.1 - 0.0014 18.8 2.3 0.002 18.4 0.0 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein p450 PF00067.22 EGO24679.1 - 1.7e-73 247.9 0.0 4.3e-73 246.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.17 EGO24680.1 - 1.7e-36 125.8 0.0 2.6e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO24680.1 - 1.1e-30 107.0 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGO24680.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGO24680.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DSBA PF01323.20 EGO24683.1 - 2.3e-29 102.6 0.1 2.8e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGO24683.1 - 5.3e-06 26.7 0.7 9.5e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EGO24683.1 - 0.0054 16.7 0.1 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_5 PF13743.6 EGO24683.1 - 0.0058 16.3 1.5 0.0081 15.9 1.5 1.4 1 1 0 1 1 1 1 Thioredoxin Frag1 PF10277.9 EGO24684.1 - 2.1e-36 125.5 13.2 2.5e-36 125.3 13.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EI24 PF07264.11 EGO24684.1 - 0.0028 17.9 13.9 0.01 16.1 13.9 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Abhydrolase_9_N PF15420.6 EGO24684.1 - 8.4 6.3 6.6 4.6 7.2 0.8 2.9 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus DXP_synthase_N PF13292.6 EGO24687.1 - 0.027 13.7 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase p450 PF00067.22 EGO24688.1 - 4.5e-71 240.0 0.0 1.3e-70 238.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DPM3 PF08285.11 EGO24688.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Retrotran_gag_2 PF14223.6 EGO24689.1 - 3e-18 65.8 0.9 3.9e-18 65.5 0.9 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Cullin_binding PF03556.15 EGO24689.1 - 0.049 14.1 0.9 0.064 13.7 0.6 1.4 1 1 0 1 1 1 0 Cullin binding gag-asp_proteas PF13975.6 EGO24691.1 - 0.059 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 EGO24692.1 - 0.00017 21.5 3.7 0.00017 21.5 3.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO24692.1 - 0.002 18.1 3.7 0.002 18.1 3.7 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO24692.1 - 0.21 11.3 1.0 0.48 10.2 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DEC-1_N PF04625.13 EGO24695.1 - 1.7 7.5 9.3 2 7.3 9.3 1.2 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region adh_short PF00106.25 EGO24697.1 - 2.1e-37 128.5 0.0 2.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO24697.1 - 1.2e-28 100.2 0.0 1.6e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO24697.1 - 3.5e-08 33.6 0.0 6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO24697.1 - 0.0003 20.7 0.1 0.00066 19.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO24697.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO24697.1 - 0.0024 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO24697.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 EGO24698.1 - 3.1e-73 247.1 0.0 6e-73 246.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 EGO24700.1 - 1e-08 35.3 0.0 5.2e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO24700.1 - 1.3e-05 25.6 0.0 4.3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EGO24700.1 - 0.00068 19.0 0.0 0.0021 17.4 0.0 1.7 1 1 1 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 EGO24700.1 - 0.042 14.1 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGO24700.1 - 0.066 13.6 0.0 0.23 11.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGO24700.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGO24700.1 - 0.11 12.1 0.6 1.2 8.7 0.6 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGO24700.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 1 0 1 1 1 0 NTPase RNA_helicase PF00910.22 EGO24700.1 - 0.17 12.2 0.1 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase LRR_4 PF12799.7 EGO24703.1 - 0.062 13.7 0.0 0.62 10.6 0.0 2.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DEAD PF00270.29 EGO24705.1 - 3.7e-39 134.3 0.0 7.4e-39 133.3 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO24705.1 - 1.2e-20 73.9 0.0 4.7e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO24705.1 - 1.5e-09 38.1 0.1 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGO24705.1 - 0.05 13.9 0.2 1.5 9.1 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO24705.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AP3D1 PF06375.11 EGO24705.1 - 0.13 12.5 17.4 0.25 11.6 17.4 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 YL1 PF05764.13 EGO24705.1 - 0.21 11.7 19.1 0.38 10.8 19.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2151 PF10221.9 EGO24705.1 - 0.4 9.2 4.2 0.54 8.8 4.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 EGO24705.1 - 0.93 7.7 14.6 1.3 7.2 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EGO24705.1 - 2.3 6.9 8.2 3.2 6.4 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dynactin_p62 PF05502.13 EGO24705.1 - 9.1 4.9 9.9 13 4.4 9.9 1.1 1 0 0 1 1 1 0 Dynactin p62 family ABC_tran PF00005.27 EGO24706.1 - 1.3e-39 135.8 0.0 9.7e-28 97.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO24706.1 - 2.9e-32 112.4 28.2 1.3e-16 61.1 14.0 3.8 2 2 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO24706.1 - 0.0049 16.3 0.0 0.18 11.3 0.0 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO24706.1 - 0.018 15.1 0.5 0.057 13.5 0.5 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Phage_holin_3_1 PF05106.12 EGO24706.1 - 0.14 12.6 3.5 0.31 11.5 0.2 3.1 4 0 0 4 4 4 0 Phage holin family (Lysis protein S) p450 PF00067.22 EGO24707.1 - 2.4e-62 211.2 0.1 5.4e-62 210.0 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 DPM3 PF08285.11 EGO24707.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) XFP_N PF09364.10 EGO24709.1 - 4.7e-149 496.2 0.0 6e-149 495.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EGO24709.1 - 2.8e-77 258.4 0.0 5.6e-77 257.4 0.0 1.5 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EGO24709.1 - 4e-77 258.3 0.0 6.7e-77 257.5 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 EGO24709.1 - 0.0012 18.7 0.1 0.0032 17.3 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 EGO24709.1 - 0.12 12.2 0.5 0.27 11.1 0.5 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain p450 PF00067.22 EGO24710.1 - 2.6e-56 191.3 0.0 3.7e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO24711.1 - 6.3e-60 203.2 0.0 8.2e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FUSC PF04632.12 EGO24711.1 - 1.4 7.3 3.5 2.3 6.7 3.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 EGO24714.1 - 3.6e-15 56.1 0.0 5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO24714.1 - 3.9e-06 26.3 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO24714.1 - 0.043 13.7 0.0 2.8 7.8 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family DDE_1 PF03184.19 EGO24715.1 - 2.7e-16 59.7 0.0 1.1e-15 57.8 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease SL4P PF17618.2 EGO24715.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein HrpJ PF07201.11 EGO24717.1 - 0.027 14.8 0.3 0.037 14.3 0.3 1.3 1 0 0 1 1 1 0 HrpJ-like domain Phe_tRNA-synt_N PF02912.18 EGO24717.1 - 0.029 14.3 0.8 0.048 13.6 0.8 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain MFS_1 PF07690.16 EGO24721.1 - 2e-10 40.2 24.4 2e-10 40.2 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RPEL PF02755.15 EGO24721.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 RPEL repeat DUF3341 PF11821.8 EGO24721.1 - 0.32 10.6 5.1 0.88 9.2 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Sugar_tr PF00083.24 EGO24723.1 - 2.5e-37 128.8 34.6 4.5e-34 118.1 34.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO24723.1 - 2.9e-22 79.1 42.4 4e-15 55.6 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DSS1_SEM1 PF05160.13 EGO24724.1 - 2e-22 79.0 9.3 2e-22 79.0 9.3 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family SIR2 PF02146.17 EGO24725.1 - 6.2e-29 101.2 0.0 1.4e-18 67.4 0.0 2.5 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 EGO24725.1 - 0.09 12.5 0.4 2 8.1 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 EGO24728.1 - 9.3e-26 90.3 0.8 1.4e-25 89.8 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO24728.1 - 6.9e-20 72.5 0.0 1.3e-19 71.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO24728.1 - 1.5e-11 44.1 0.0 4.2e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAGK_cat PF00781.24 EGO24728.1 - 0.03 13.9 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain AlaDh_PNT_C PF01262.21 EGO24728.1 - 0.055 12.8 0.8 0.077 12.3 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2862 PF11061.8 EGO24728.1 - 0.11 12.4 0.2 26 4.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) WD40 PF00400.32 EGO24730.1 - 2.7e-19 69.2 8.8 0.0038 18.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO24730.1 - 1.9e-09 37.7 0.1 0.006 16.9 0.1 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO24730.1 - 0.00083 19.3 0.1 0.07 13.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO24730.1 - 0.00098 18.5 0.0 0.016 14.6 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 EGO24730.1 - 0.0095 14.3 0.0 2.4 6.3 0.0 2.4 1 1 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz LEM PF03020.15 EGO24730.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 LEM domain Ge1_WD40 PF16529.5 EGO24730.1 - 0.056 12.4 0.0 5.1 5.9 0.0 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_zinc_N_2 PF13602.6 EGO24731.1 - 8.2e-14 52.8 0.0 1.3e-13 52.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO24731.1 - 9.4e-13 48.3 0.2 1.4e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO24731.1 - 1.4e-09 37.8 0.1 3.8e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGO24731.1 - 0.025 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase FA_hydroxylase PF04116.13 EGO24732.1 - 2.7e-24 86.0 20.9 2.7e-24 86.0 20.9 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily eIF3_N PF09440.10 EGO24733.1 - 1.4e-46 158.2 4.4 1.4e-46 158.2 4.4 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGO24733.1 - 2.5e-08 34.4 0.3 9.6e-08 32.5 0.1 2.1 2 0 0 2 2 2 1 PCI domain RIH_assoc PF08454.11 EGO24733.1 - 0.06 13.2 0.2 0.16 11.8 0.2 1.7 1 1 0 1 1 1 0 RyR and IP3R Homology associated Asp PF00026.23 EGO24734.1 - 2.1e-18 66.8 0.3 2.4e-18 66.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO24734.1 - 3.9e-09 37.0 0.2 7e-09 36.2 0.2 1.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Pex14_N PF04695.13 EGO24735.1 - 5.6e-19 69.3 11.5 3e-13 50.7 0.1 3.0 2 1 1 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT57 PF10498.9 EGO24735.1 - 0.00031 19.8 4.5 0.00044 19.3 4.5 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 V_ATPase_I PF01496.19 EGO24735.1 - 0.0007 17.7 0.0 0.0007 17.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ING PF12998.7 EGO24735.1 - 0.0024 18.4 6.1 0.0032 18.0 5.4 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding LXG PF04740.12 EGO24735.1 - 0.0069 16.1 5.1 0.011 15.5 5.1 1.3 1 0 0 1 1 1 1 LXG domain of WXG superfamily Laminin_II PF06009.12 EGO24735.1 - 0.0085 16.1 12.2 0.012 15.6 10.5 1.8 2 0 0 2 2 2 1 Laminin Domain II Phlebovirus_NSM PF07246.11 EGO24735.1 - 0.0094 15.4 2.8 0.014 14.8 2.8 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M BicD PF09730.9 EGO24735.1 - 0.028 12.9 7.6 0.044 12.2 7.6 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Spc7 PF08317.11 EGO24735.1 - 0.028 13.3 11.3 0.043 12.7 11.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ISG65-75 PF11727.8 EGO24735.1 - 0.044 13.0 4.1 0.062 12.5 4.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein MCPsignal PF00015.21 EGO24735.1 - 0.055 13.3 7.0 0.088 12.6 7.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cas_DxTHG PF09455.10 EGO24735.1 - 0.072 12.7 0.7 0.098 12.2 0.7 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family NPV_P10 PF05531.12 EGO24735.1 - 0.081 13.4 11.5 0.29 11.6 1.3 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 EGO24735.1 - 0.086 12.3 10.6 0.13 11.7 10.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Pox_F16 PF04708.12 EGO24735.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein UPF0242 PF06785.11 EGO24735.1 - 0.11 12.5 6.2 0.17 12.0 6.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 EGO24735.1 - 0.11 11.3 0.6 0.14 11.0 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Aida_N PF08910.10 EGO24735.1 - 0.12 12.8 4.3 0.22 11.9 4.3 1.5 1 0 0 1 1 1 0 Aida N-terminus Allexi_40kDa PF05549.11 EGO24735.1 - 0.15 11.6 1.8 0.31 10.5 1.8 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein Atg14 PF10186.9 EGO24735.1 - 0.15 11.1 1.9 0.22 10.6 1.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EGO24735.1 - 0.21 11.6 11.0 0.46 10.5 8.4 2.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EGO24735.1 - 0.21 11.8 6.0 0.6 10.4 6.0 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 EGO24735.1 - 0.24 10.6 5.9 0.35 10.1 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF763 PF05559.11 EGO24735.1 - 0.26 10.4 2.2 0.36 10.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF3584 PF12128.8 EGO24735.1 - 0.26 8.8 10.4 0.35 8.3 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) L31 PF09784.9 EGO24735.1 - 0.29 11.6 3.4 0.61 10.5 3.4 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF4191 PF13829.6 EGO24735.1 - 0.35 10.2 3.3 0.5 9.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Spectrin PF00435.21 EGO24735.1 - 0.38 11.3 9.1 0.1 13.1 4.6 2.1 1 1 1 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 EGO24735.1 - 0.46 10.5 3.8 0.26 11.3 1.6 1.7 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EGO24735.1 - 0.48 8.3 3.4 0.68 7.8 3.4 1.1 1 0 0 1 1 1 0 Prominin Methyltransf_14 PF08484.11 EGO24735.1 - 0.58 10.0 3.2 0.96 9.2 3.2 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain DUF1043 PF06295.12 EGO24735.1 - 0.61 10.1 5.4 1.4 9.0 3.0 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF1043) BshC PF10079.9 EGO24735.1 - 0.67 8.6 8.2 0.93 8.2 8.2 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF2968 PF11180.8 EGO24735.1 - 0.95 9.1 11.1 1.7 8.2 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_13 PF13166.6 EGO24735.1 - 1.2 7.7 6.4 1.6 7.3 6.4 1.1 1 0 0 1 1 1 0 AAA domain Baculo_p24 PF05073.12 EGO24735.1 - 1.4 8.7 5.1 2 8.1 3.2 2.0 2 1 0 2 2 2 0 Baculovirus P24 capsid protein Fib_alpha PF08702.10 EGO24735.1 - 1.7 8.8 7.2 2.9 8.1 7.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EGO24735.1 - 1.7 9.2 15.1 0.4 11.2 12.0 1.4 2 0 0 2 2 1 0 Apg6 coiled-coil region Nup88 PF10168.9 EGO24735.1 - 2 6.1 7.9 2.9 5.6 7.9 1.1 1 0 0 1 1 1 0 Nuclear pore component dCache_2 PF08269.11 EGO24735.1 - 3.8 6.6 6.2 5.3 6.1 6.2 1.2 1 0 0 1 1 1 0 Cache domain MCU PF04678.13 EGO24735.1 - 4 7.5 6.1 6 6.9 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PSK_trans_fac PF07704.11 EGO24735.1 - 4.6 8.1 10.1 4.5 8.1 7.8 2.3 2 1 0 2 2 1 0 Rv0623-like transcription factor Med9 PF07544.13 EGO24735.1 - 5 7.3 13.4 2.9 8.1 9.2 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RecG_N PF17190.4 EGO24735.1 - 6 7.7 7.8 18 6.2 3.5 2.3 1 1 1 2 2 2 0 RecG N-terminal helical domain kleA_kleC PF17383.2 EGO24735.1 - 6.8 7.1 9.2 0.43 10.9 0.6 2.5 2 1 1 3 3 2 0 Uncharacterized KorC regulated protein A Agglutinin_C PF18021.1 EGO24736.1 - 0.096 13.2 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Agglutinin C-terminal Lectin_C_term PF18022.1 EGO24736.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain BRO1 PF03097.18 EGO24737.1 - 3.4e-108 361.9 0.3 5.7e-108 361.2 0.3 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGO24737.1 - 1.8e-76 257.2 13.5 1.8e-76 257.2 13.5 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Vezatin PF12632.7 EGO24737.1 - 0.077 12.4 1.2 0.4 10.0 0.3 2.6 2 1 0 2 2 2 0 Mysoin-binding motif of peroxisomes Stm1_N PF09598.10 EGO24737.1 - 1.5 9.7 5.1 3 8.8 1.4 2.6 2 0 0 2 2 2 0 Stm1 DUF3421 PF11901.8 EGO24738.1 - 4.9e-29 100.7 0.0 6.8e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) WLM PF08325.10 EGO24739.1 - 1.1e-30 107.2 3.4 1.5e-29 103.5 3.4 2.5 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 EGO24739.1 - 3e-05 24.1 0.7 3e-05 24.1 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 EGO24739.1 - 0.018 14.9 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 SprT-like family PQ-loop PF04193.14 EGO24740.1 - 8.3e-21 73.5 7.7 3.7e-10 39.4 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EGO24740.1 - 0.11 13.3 3.6 0.21 12.4 3.6 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor Acetate_kinase PF00871.17 EGO24742.1 - 5.3e-95 318.4 0.1 1.2e-94 317.2 0.1 1.5 1 1 0 1 1 1 1 Acetokinase family p450 PF00067.22 EGO24743.1 - 3.6e-47 161.2 0.0 4.2e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO24744.1 - 0.035 12.9 0.0 0.037 12.8 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.22 EGO24745.1 - 7.7e-76 255.7 0.0 9.3e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 EGO24746.1 - 8.2e-169 562.7 3.6 5.1e-85 286.3 0.1 3.1 2 2 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO24746.1 - 2.3e-16 60.3 8.7 3.5e-08 33.6 1.3 3.7 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO24746.1 - 2.2e-08 33.8 0.8 0.0029 17.1 0.1 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Septum_form PF13845.6 EGO24746.1 - 0.061 12.8 0.1 10 5.6 0.1 2.4 2 0 0 2 2 2 0 Septum formation Say1_Mug180 PF10340.9 EGO24746.1 - 0.12 11.2 0.1 21 3.8 0.0 3.0 3 0 0 3 3 3 0 Steryl acetyl hydrolase RL11D PF11088.8 EGO24746.1 - 0.98 9.8 10.4 25 5.2 0.0 4.3 4 0 0 4 4 4 0 Glycoprotein encoding membrane proteins RL5A and RL6 Arv1 PF04161.13 EGO24747.1 - 2.3e-38 132.5 0.0 3.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family DUF410 PF04190.13 EGO24748.1 - 1.3e-75 254.5 0.0 2e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_7 PF13176.6 EGO24748.1 - 0.15 12.2 0.3 3.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HSBP1 PF06825.12 EGO24749.1 - 6.3e-21 74.0 3.6 8.2e-21 73.6 3.6 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 EGO24749.1 - 0.031 14.3 0.2 0.04 14.0 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 EGO24749.1 - 0.11 12.9 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 EGO24749.1 - 0.13 12.2 0.4 1.5 8.7 0.4 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Terpene_synth_C PF03936.16 EGO24750.1 - 2.1e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ank PF00023.30 EGO24751.1 - 3.5e-13 49.4 0.1 0.0013 19.1 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGO24751.1 - 1.4e-12 48.1 0.0 1e-11 45.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO24751.1 - 1.5e-12 47.7 0.1 2.2e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO24751.1 - 2.1e-11 43.8 0.5 0.00048 20.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO24751.1 - 1.1e-10 40.8 0.0 0.007 16.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat rve PF00665.26 EGO24755.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.7 2 1 1 3 3 3 1 Integrase core domain DDE_3 PF13358.6 EGO24755.1 - 0.0098 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease NADH_4Fe-4S PF10589.9 EGO24757.1 - 0.042 13.9 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Tfb2 PF03849.14 EGO24758.1 - 4.1e-140 466.8 0.1 4.8e-140 466.6 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGO24758.1 - 3.1e-25 88.4 0.1 6.7e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGO24758.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GRIP PF01465.20 EGO24758.1 - 0.16 11.9 0.7 0.46 10.4 0.7 1.8 1 0 0 1 1 1 0 GRIP domain Terpene_synth_C PF03936.16 EGO24760.1 - 2.1e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 EGO24760.1 - 0.019 15.1 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Aldo_ket_red PF00248.21 EGO24762.1 - 3.6e-40 138.0 0.0 1.1e-29 103.6 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family zf-RING_5 PF14634.6 EGO24764.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TRH PF05438.12 EGO24767.1 - 0.065 13.0 0.0 0.072 12.8 0.0 1.0 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Nfu_N PF08712.11 EGO24767.1 - 0.16 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Sugar_tr PF00083.24 EGO24769.1 - 4.9e-111 371.8 27.5 5.6e-111 371.6 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO24769.1 - 1.8e-20 73.2 46.3 6.2e-19 68.1 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WBS28 PF15164.6 EGO24771.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Williams-Beuren syndrome chromosomal region 28 protein homologue Baculo_PEP_C PF04513.12 EGO24773.1 - 0.012 15.6 1.2 0.16 12.0 1.2 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGO24773.1 - 0.017 15.1 2.8 0.45 10.5 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 EGO24773.1 - 0.08 12.9 0.0 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 EGO24773.1 - 0.14 12.4 1.3 0.77 9.9 0.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5549 PF17703.1 EGO24773.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Plavaka PF18759.1 EGO24774.1 - 4.3e-23 82.1 0.0 5.8e-16 58.6 0.0 2.0 1 1 1 2 2 2 2 Plavaka transposase PX PF00787.24 EGO24777.1 - 0.00017 21.6 0.1 0.0014 18.6 0.1 2.3 1 1 0 1 1 1 1 PX domain DUF2396 PF09654.10 EGO24777.1 - 0.023 14.8 0.3 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) PTRF_SDPR PF15237.6 EGO24777.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PTRF/SDPR family PB1 PF00564.24 EGO24778.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 PB1 domain Actin PF00022.19 EGO24779.1 - 1.5e-41 142.4 0.0 4.8e-40 137.4 0.0 2.8 1 1 0 1 1 1 1 Actin P2 PF07194.11 EGO24780.1 - 0.013 15.6 0.2 6 7.0 0.0 2.2 2 0 0 2 2 2 0 P2 response regulator binding domain PNK3P PF08645.11 EGO24781.1 - 9.6e-45 152.2 0.1 1.7e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGO24781.1 - 1.4e-15 57.7 0.0 1.2e-12 48.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain LNS2 PF08235.13 EGO24781.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Zeta_toxin PF06414.12 EGO24781.1 - 0.072 12.4 0.0 15 4.8 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin MFS_1 PF07690.16 EGO24783.1 - 3e-29 102.1 19.0 3e-29 102.1 19.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO24783.1 - 2.5e-10 39.8 16.0 9.1e-08 31.4 0.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO24784.1 - 8e-34 117.1 16.8 1.2e-33 116.5 16.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO24784.1 - 9.9e-06 24.7 18.1 0.00011 21.3 3.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EGO24784.1 - 0.00073 18.1 0.6 0.0013 17.3 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 EGO24784.1 - 0.039 12.2 2.3 0.076 11.2 2.3 1.4 1 0 0 1 1 1 0 BT1 family DUF2628 PF10947.8 EGO24784.1 - 2.5 8.5 4.3 3.7 8.0 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) ENT PF03735.14 EGO24788.1 - 0.012 15.7 0.1 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 ENT domain HAD_SAK_1 PF10307.9 EGO24788.1 - 0.19 11.5 3.0 0.34 10.7 3.0 1.3 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Fer4_13 PF13370.6 EGO24788.1 - 0.23 12.0 4.8 0.14 12.7 1.3 2.3 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF3460 PF11943.8 EGO24788.1 - 8.2 6.8 8.5 2.5 8.4 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Retrotrans_gag PF03732.17 EGO24789.1 - 0.049 13.9 0.2 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4939 PF16297.5 EGO24789.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) p450 PF00067.22 EGO24791.1 - 1.3e-69 235.1 0.0 1.7e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Svf1_C PF17187.4 EGO24792.1 - 1.7e-49 167.9 0.0 2.2e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EGO24792.1 - 1.1e-45 155.6 0.0 1.4e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Peptidase_M48 PF01435.18 EGO24794.1 - 6.7e-18 65.2 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Pax7 PF12360.8 EGO24794.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Paired box protein 7 AA_permease_2 PF13520.6 EGO24795.1 - 2.6e-63 214.3 39.1 3.3e-63 214.0 39.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF5337 PF17272.2 EGO24795.1 - 5.9 6.8 7.0 0.86 9.5 0.4 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5337) TPR_19 PF14559.6 EGO24796.1 - 6.8e-10 39.3 6.7 8.1e-05 23.1 0.4 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO24796.1 - 6.9e-09 35.2 2.5 1.2 9.4 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO24796.1 - 9.6e-09 35.8 4.3 0.00015 22.4 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO24796.1 - 4.8e-07 29.3 0.0 7.9 6.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO24796.1 - 3.7e-06 27.3 10.6 1.4 9.9 0.1 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO24796.1 - 0.00013 22.1 0.1 0.12 12.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO24796.1 - 0.00022 21.2 0.2 4.4 7.8 0.0 4.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO24796.1 - 0.00032 20.9 6.7 0.25 11.7 0.1 4.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24796.1 - 0.00056 19.8 0.8 31 4.9 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO24796.1 - 0.00066 19.9 0.1 0.68 10.2 0.0 3.7 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGO24796.1 - 0.18 12.5 4.8 16 6.4 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGO24796.1 - 0.25 12.1 0.0 0.25 12.1 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO24796.1 - 0.58 10.4 3.4 4 7.7 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat PfkB PF00294.24 EGO24797.1 - 3.1e-08 33.3 0.3 0.00074 18.9 0.5 3.4 3 1 0 3 3 3 2 pfkB family carbohydrate kinase PARP PF00644.20 EGO24799.1 - 1.7e-12 47.3 0.2 2.6e-09 36.9 0.2 2.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 EGO24800.1 - 5.2e-12 45.8 0.5 6.9e-09 35.6 0.0 2.9 1 1 2 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain LRV_FeS PF05484.11 EGO24800.1 - 0.15 12.1 1.4 0.32 11.0 1.4 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster DUF155 PF02582.14 EGO24802.1 - 1e-45 156.0 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 NADHdh_A3 PF14987.6 EGO24803.1 - 0.09 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Ank PF00023.30 EGO24805.1 - 0.00047 20.5 0.2 0.77 10.3 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGO24805.1 - 0.0016 19.0 0.0 0.042 14.4 0.0 2.1 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO24805.1 - 0.035 14.4 0.2 0.09 13.1 0.2 1.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO24805.1 - 0.037 14.6 0.1 0.33 11.6 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO24805.1 - 0.13 12.9 0.1 72 4.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat p450 PF00067.22 EGO24806.1 - 9.4e-64 215.8 0.0 1.4e-63 215.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ADH_N_2 PF16884.5 EGO24808.1 - 3.1e-30 104.2 0.0 7.6e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGO24808.1 - 3.4e-21 75.6 0.0 5.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO24808.1 - 9.7e-10 39.6 0.0 1.8e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EGO24808.1 - 0.088 12.5 0.2 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MIP PF00230.20 EGO24809.1 - 2.9e-29 102.4 5.3 4.2e-29 101.9 5.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF819 PF05684.12 EGO24809.1 - 0.0071 15.4 0.8 0.019 14.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF819) Mad3_BUB1_I PF08311.12 EGO24812.1 - 7.8e-37 126.0 0.6 1.3e-36 125.3 0.6 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EGO24812.1 - 6.3e-13 48.7 0.0 1.8e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO24812.1 - 5.4e-06 25.9 0.0 8.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 EGO24812.1 - 1.8e-05 24.8 0.0 5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 EGO24812.1 - 0.0016 18.5 0.0 0.0048 17.0 0.0 1.7 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein TPR_14 PF13428.6 EGO24812.1 - 0.24 12.3 2.2 1 10.4 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4634 PF15465.6 EGO24816.1 - 0.014 15.7 0.4 0.019 15.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) RhoGEF PF00621.20 EGO24819.1 - 1.1e-32 113.7 0.8 1.8e-32 113.0 0.8 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 EGO24819.1 - 2.8e-29 102.6 0.0 4.1e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EGO24819.1 - 1.1e-12 48.2 0.0 3.9e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGO24819.1 - 0.001 19.6 0.0 0.0026 18.2 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_16 PF17838.1 EGO24819.1 - 0.0031 17.4 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 PH domain WD40 PF00400.32 EGO24820.1 - 1.4e-33 114.3 19.3 4e-08 33.8 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO24820.1 - 7.7e-14 51.8 0.0 0.00034 20.8 0.0 5.8 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO24820.1 - 8.2e-08 31.6 0.1 0.0033 16.4 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO24820.1 - 0.00056 19.3 0.0 0.11 11.7 0.0 3.3 3 1 0 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 EGO24820.1 - 0.0025 17.4 4.4 0.14 11.8 0.1 3.1 1 1 2 3 3 3 2 PQQ-like domain WDCP PF15390.6 EGO24820.1 - 0.05 12.0 0.0 0.071 11.5 0.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Thioredoxin PF00085.20 EGO24821.1 - 2.6e-55 184.7 0.0 1.7e-26 92.2 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGO24821.1 - 1.5e-23 83.5 0.3 3e-23 82.5 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EGO24821.1 - 2e-14 53.7 0.0 3.1e-06 26.7 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGO24821.1 - 3.4e-14 53.2 0.0 9.1e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGO24821.1 - 3.8e-10 40.0 0.0 0.015 15.6 0.0 3.5 2 1 1 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.6 EGO24821.1 - 4.6e-10 39.5 0.0 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EGO24821.1 - 3.5e-07 30.2 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EGO24821.1 - 3.1e-05 23.7 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 EGO24821.1 - 0.00014 21.8 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 EGO24821.1 - 0.0015 18.4 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EGO24821.1 - 0.0071 16.5 0.7 1.4 9.2 0.1 2.9 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.6 EGO24821.1 - 0.017 14.9 0.1 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin Exo_endo_phos PF03372.23 EGO24822.1 - 3e-09 36.7 0.1 4.1e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.24 EGO24824.1 - 5.4e-73 246.4 19.3 6.1e-73 246.2 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO24824.1 - 7.6e-29 100.7 33.5 1.1e-22 80.5 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO24824.1 - 0.0034 15.9 8.0 0.0076 14.7 4.0 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Alpha-amylase PF00128.24 EGO24825.1 - 1.2e-21 77.6 0.0 3.9e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EGO24825.1 - 8.4e-06 24.3 0.3 0.011 14.0 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Totivirus_coat PF05518.11 EGO24826.1 - 2.6 6.0 5.2 3.3 5.6 5.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Acetyltransf_3 PF13302.7 EGO24827.1 - 3.5e-11 43.9 0.0 4.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO24827.1 - 0.0054 17.0 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_31 PF13847.6 EGO24828.1 - 2.4e-30 105.4 0.0 3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO24828.1 - 1.3e-25 90.0 0.0 2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO24828.1 - 3.5e-24 85.3 0.0 5.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO24828.1 - 4.2e-18 65.5 0.0 5.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO24828.1 - 7.3e-18 64.9 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO24828.1 - 5e-17 62.5 0.0 7.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO24828.1 - 8.3e-12 45.3 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGO24828.1 - 2.6e-07 30.4 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EGO24828.1 - 6.5e-07 29.0 0.0 1.3e-06 28.0 0.0 1.6 2 0 0 2 2 1 1 Putative methyltransferase MTS PF05175.14 EGO24828.1 - 1.8e-06 27.6 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGO24828.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EGO24828.1 - 0.00025 20.2 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 EGO24828.1 - 0.001 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_9 PF08003.11 EGO24828.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) V_cholerae_RfbT PF05575.11 EGO24828.1 - 0.0028 17.0 0.0 0.22 10.7 0.0 2.1 1 1 1 2 2 2 1 Vibrio cholerae RfbT protein Methyltransf_29 PF03141.16 EGO24828.1 - 0.003 16.2 0.0 0.0046 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 EGO24828.1 - 0.0041 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 EGO24828.1 - 0.005 16.0 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 EGO24828.1 - 0.0061 16.6 0.0 0.0085 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO24828.1 - 0.0078 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EGO24828.1 - 0.045 13.3 0.0 0.095 12.2 0.0 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase GidB PF02527.15 EGO24828.1 - 0.053 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 EGO24828.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGO24828.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3759 PF12585.8 EGO24829.1 - 6.9e-33 112.5 10.0 8.4e-33 112.3 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RNase_HII PF01351.18 EGO24830.1 - 2.7e-48 164.4 0.0 6.9e-48 163.1 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease HII CAT_RBD PF03123.15 EGO24830.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 CAT RNA binding domain p450 PF00067.22 EGO24831.1 - 6.4e-72 242.8 0.0 8.1e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO24832.1 - 2.2e-79 267.4 0.0 2.4e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TruD PF01142.18 EGO24832.1 - 0.048 12.5 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) F-box-like PF12937.7 EGO24836.1 - 5.1e-08 32.7 0.7 1.3e-07 31.4 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO24836.1 - 2.9e-05 23.8 0.2 9.8e-05 22.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain Xpo1 PF08389.12 EGO24837.1 - 6e-16 58.8 5.4 2.5e-15 56.8 0.0 4.4 4 2 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EGO24837.1 - 0.017 15.3 0.3 4.1 7.9 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat ERAP1_C PF11838.8 EGO24837.1 - 0.034 13.7 0.0 0.13 11.7 0.0 2.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain MIT PF04212.18 EGO24837.1 - 0.088 12.9 0.2 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Cullin PF00888.22 EGO24838.1 - 6.8e-212 705.4 0.0 8.6e-212 705.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGO24838.1 - 8e-28 96.3 1.4 8e-28 96.3 1.4 2.3 3 0 0 3 3 3 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EGO24838.1 - 0.099 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Penicillinase repressor DnaJ_C PF01556.18 EGO24839.1 - 3.4e-29 101.9 0.0 5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO24839.1 - 1.9e-24 85.6 3.4 3e-24 84.9 3.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO24839.1 - 6.7e-14 52.0 16.3 1.1e-13 51.3 16.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGO24839.1 - 2.1e-05 24.4 7.5 0.0016 18.4 0.2 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGO24839.1 - 0.00066 19.7 3.8 0.47 10.5 1.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EGO24839.1 - 0.24 11.0 5.9 0.32 10.6 0.8 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_6 PF14599.6 EGO24839.1 - 0.59 10.2 5.1 0.96 9.5 0.5 2.5 2 0 0 2 2 2 0 Zinc-ribbon Lar_restr_allev PF14354.6 EGO24839.1 - 0.66 10.4 11.3 0.99 9.8 0.2 3.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Stc1 PF12898.7 EGO24839.1 - 1.1 9.8 7.0 0.81 10.3 1.3 2.4 1 1 1 2 2 2 0 Stc1 domain Mito_carr PF00153.27 EGO24840.1 - 4.2e-52 174.1 0.9 9.7e-20 70.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 EGO24846.1 - 2.7e-14 52.7 12.9 9.8e-05 22.6 0.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO24846.1 - 1.6e-10 40.9 12.4 0.0046 17.7 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO24846.1 - 5.9e-10 39.1 17.0 1.5e-05 25.2 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGO24846.1 - 3.5e-05 23.7 6.6 0.019 14.9 0.1 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGO24846.1 - 0.0022 18.2 3.6 0.012 15.8 3.3 1.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EGO24846.1 - 0.0035 17.5 3.1 1 9.5 0.0 2.9 1 1 2 3 3 3 2 Aberrant zinc-finger FOXP-CC PF16159.5 EGO24846.1 - 0.0064 17.1 8.0 0.49 11.1 4.8 2.8 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EGO24846.1 - 0.0075 16.5 5.6 0.51 10.7 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO24846.1 - 0.0088 16.4 6.4 0.61 10.6 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EGO24846.1 - 0.11 12.4 6.2 0.81 9.6 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 EGO24846.1 - 0.15 11.8 5.9 11 5.9 0.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EGO24846.1 - 0.25 11.3 0.1 0.25 11.3 0.1 3.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 EGO24846.1 - 0.33 11.4 7.7 1.1 9.8 1.1 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 EGO24846.1 - 3.7 7.8 12.1 3.4 7.9 4.4 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger mono-CXXC PF15626.6 EGO24847.1 - 0.43 11.0 2.8 0.9 9.9 2.8 1.5 1 0 0 1 1 1 0 single CXXC unit UL17 PF17640.2 EGO24849.1 - 0.012 15.7 0.5 0.067 13.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized UL17 SMN PF06003.12 EGO24849.1 - 0.092 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4112 PF13430.6 EGO24851.1 - 5e-34 116.7 0.2 6.5e-34 116.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) YbhQ PF11076.8 EGO24851.1 - 0.14 12.1 0.2 0.21 11.6 0.2 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Sporozoite_P67 PF05642.11 EGO24852.1 - 4.8 5.2 10.3 6.6 4.7 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FtsJ PF01728.19 EGO24854.1 - 4.2e-12 46.5 0.0 6.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EGO24854.1 - 0.0033 17.1 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Hus1 PF04005.12 EGO24854.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein FtsJ PF01728.19 EGO24855.1 - 1.9e-09 37.9 0.0 3.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cadherin_C PF01049.17 EGO24855.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region Methyltr_RsmB-F PF01189.17 EGO24855.1 - 0.043 13.5 0.0 0.24 11.0 0.0 2.1 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EGO24855.1 - 0.083 12.7 0.5 6.8 6.5 0.0 2.7 1 1 2 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGO24855.1 - 0.16 12.7 0.0 1.1 10.0 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain bZIP_1 PF00170.21 EGO24857.1 - 0.0029 17.7 2.1 0.0029 17.7 2.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor YabA PF06156.13 EGO24857.1 - 0.0044 17.6 2.3 0.0065 17.1 2.1 1.5 1 1 0 1 1 1 1 Initiation control protein YabA Shugoshin_N PF07558.11 EGO24857.1 - 0.0073 16.2 0.8 0.016 15.0 0.8 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region KASH_CCD PF14662.6 EGO24857.1 - 0.0086 15.9 4.6 0.011 15.6 3.3 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 EGO24857.1 - 0.023 15.1 2.6 0.023 15.1 2.6 2.0 1 1 1 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 EGO24857.1 - 0.051 13.8 3.0 0.051 13.8 3.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper K-box PF01486.17 EGO24857.1 - 0.07 13.3 2.8 0.11 12.7 2.8 1.4 1 0 0 1 1 1 0 K-box region DivIC PF04977.15 EGO24857.1 - 0.32 10.8 6.2 0.16 11.7 3.7 1.8 1 1 0 2 2 2 0 Septum formation initiator DUF1771 PF08590.10 EGO24859.1 - 0.044 14.1 1.1 0.067 13.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_6 PF15288.6 EGO24859.1 - 0.05 13.5 0.9 0.91 9.4 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO24859.1 - 0.057 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO24859.1 - 0.095 12.5 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger DUF4718 PF15842.5 EGO24859.1 - 0.14 12.0 0.5 0.17 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Retrotrans_gag PF03732.17 EGO24860.1 - 3.1e-06 27.4 2.5 3.1e-06 27.4 2.5 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO24860.1 - 1.5e-05 24.8 1.7 3.4e-05 23.7 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO24860.1 - 4.8e-05 23.2 5.1 8e-05 22.5 5.1 1.4 1 0 0 1 1 1 1 Zinc knuckle M64_N PF16217.5 EGO24860.1 - 0.011 15.3 0.3 0.042 13.4 0.3 2.0 2 1 0 2 2 2 0 Peptidase M64 N-terminus DUF4939 PF16297.5 EGO24860.1 - 0.014 15.2 0.2 0.064 13.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) Dermcidin PF15291.6 EGO24862.1 - 0.016 15.7 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide MetRS-N PF09635.10 EGO24862.1 - 0.06 13.9 0.1 0.09 13.3 0.1 1.2 1 0 0 1 1 1 0 MetRS-N binding domain gag-asp_proteas PF13975.6 EGO24864.1 - 3e-07 30.9 0.0 3.5e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO24864.1 - 1.1e-06 28.5 0.0 1.2e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO24864.1 - 2.5e-06 28.0 0.0 3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Transketolase_N PF00456.21 EGO24865.1 - 8.1e-16 57.9 1.4 9.8e-15 54.3 1.4 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EGO24865.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGO24865.1 - 7.3e-06 25.8 0.1 1.3e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EGO24865.1 - 0.002 18.0 0.0 0.0075 16.1 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EGO24865.1 - 0.0037 16.3 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4478 PF14793.6 EGO24865.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Spt5_N PF11942.8 EGO24867.1 - 0.067 14.2 7.2 0.11 13.5 7.2 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.11 EGO24867.1 - 0.54 8.3 4.9 0.71 7.9 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EGO24867.1 - 0.65 8.1 4.0 0.78 7.9 4.0 1.0 1 0 0 1 1 1 0 Nop14-like family Pex14_N PF04695.13 EGO24867.1 - 4.7 7.8 17.1 9.2 6.9 17.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_pol_phi PF04931.13 EGO24867.1 - 7.8 4.5 8.3 9.5 4.2 8.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Hus1 PF04005.12 EGO24868.1 - 3.2e-75 252.9 0.2 3.6e-75 252.8 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Steroid_dh PF02544.16 EGO24870.1 - 1.5e-33 115.9 4.2 2.4e-33 115.2 4.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGO24870.1 - 0.00091 19.6 1.3 0.0018 18.6 1.3 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ubiquitin PF00240.23 EGO24870.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Abhydrolase_1 PF00561.20 EGO24871.1 - 1.9e-15 57.2 0.1 1.3e-14 54.5 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO24871.1 - 5.1e-11 43.6 0.1 6e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO24871.1 - 3.8e-09 36.2 0.0 5.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGO24871.1 - 3.7e-07 30.5 0.0 5.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGO24871.1 - 1.4e-06 28.2 0.1 9.6e-06 25.5 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGO24871.1 - 0.00018 21.1 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EGO24871.1 - 0.0061 15.9 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 EGO24871.1 - 0.0074 15.2 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 EGO24871.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 EGO24871.1 - 0.032 14.1 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase EHN PF06441.12 EGO24871.1 - 0.1 13.0 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Thioredoxin_12 PF18400.1 EGO24871.1 - 0.13 12.1 0.0 2 8.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain Chlorophyllase PF07224.11 EGO24871.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.11 EGO24871.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EGO24871.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold MIP PF00230.20 EGO24872.1 - 3.5e-44 151.2 16.3 4.3e-44 150.9 16.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein RF-1 PF00472.20 EGO24873.1 - 3.7e-20 72.0 0.6 5.7e-20 71.4 0.6 1.2 1 0 0 1 1 1 1 RF-1 domain DUF4419 PF14388.6 EGO24874.1 - 8.7e-102 340.6 0.0 1.1e-101 340.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) NADH_dehy_S2_C PF06444.11 EGO24874.1 - 0.92 10.1 3.0 2.2 8.9 3.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus DUF829 PF05705.14 EGO24875.1 - 6.1e-41 140.9 0.1 7.6e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 EGO24875.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4604 PF15377.6 EGO24876.1 - 2.8e-15 57.2 6.0 4e-15 56.7 6.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Complex1_LYR_2 PF13233.6 EGO24877.1 - 6.1e-21 75.0 0.1 8.1e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGO24877.1 - 1.6e-14 53.6 0.0 3.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EGO24877.1 - 0.00074 20.1 0.1 0.0011 19.5 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Cyanate_lyase PF02560.14 EGO24878.1 - 5.1e-34 116.0 0.0 6.9e-34 115.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EGO24878.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r1_1 PF03979.14 EGO24878.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 KorB PF08535.10 EGO24878.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 KorB domain Cyanate_lyase PF02560.14 EGO24880.1 - 6e-19 67.7 0.3 2.1e-18 65.9 0.3 1.9 1 1 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EGO24880.1 - 6e-05 23.3 0.0 8.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1479 PF07350.12 EGO24881.1 - 2.1e-132 441.9 0.0 2.5e-132 441.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EGO24881.1 - 0.00028 21.2 0.6 0.21 11.8 0.2 3.0 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Tubulin PF00091.25 EGO24882.1 - 3.1e-64 216.8 0.0 4.4e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO24882.1 - 1.2e-35 122.4 0.1 1.9e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGO24882.1 - 6.4e-08 32.9 0.1 2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGO24882.1 - 0.0065 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGO24882.1 - 0.1 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Pho88 PF10032.9 EGO24883.1 - 2.8e-75 251.6 0.0 3.1e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) PH PF00169.29 EGO24884.1 - 1.2e-05 25.8 0.0 2.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF5403 PF17395.2 EGO24884.1 - 0.17 12.2 1.0 23 5.4 0.0 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5403) Mito_carr PF00153.27 EGO24886.1 - 1.5e-64 214.0 7.0 5.5e-24 83.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Isochorismatase PF00857.20 EGO24887.1 - 9.9e-21 74.7 0.0 1.3e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF2487 PF10673.9 EGO24889.1 - 0.1 12.6 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Glutaredoxin PF00462.24 EGO24890.1 - 1.5e-19 70.0 0.1 1.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGO24890.1 - 8.3e-14 51.4 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGO24890.1 - 0.00076 19.8 0.0 0.044 14.1 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like HyaE PF07449.11 EGO24890.1 - 0.0013 18.6 0.0 0.0087 16.0 0.0 2.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EGO24890.1 - 0.0042 17.5 0.0 0.74 10.3 0.0 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGO24890.1 - 0.12 12.4 0.1 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain DIM1 PF02966.16 EGO24890.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 Mitosis protein DIM1 SH3BGR PF04908.15 EGO24890.1 - 0.18 12.0 0.0 0.44 10.7 0.0 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ku PF02735.16 EGO24891.1 - 7.8e-34 117.2 0.0 5.1e-33 114.5 0.0 2.2 2 1 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGO24891.1 - 8e-21 74.8 0.2 1.4e-20 74.0 0.2 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGO24891.1 - 3.1e-16 59.9 0.5 9.3e-16 58.3 0.3 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EGO24891.1 - 8.1e-09 35.0 0.1 1.9e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 EGO24891.1 - 0.14 12.8 0.0 1.1 9.9 0.0 2.5 1 1 0 1 1 1 0 von Willebrand factor type A domain PTPA PF03095.15 EGO24892.1 - 3.8e-101 338.5 0.0 4.5e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Orn_Arg_deC_N PF02784.16 EGO24894.1 - 4.1e-75 252.3 0.0 5.3e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGO24894.1 - 1.4e-16 60.5 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KilA-N PF04383.13 EGO24896.1 - 0.0044 16.9 0.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 2 KilA-N domain Na_sulph_symp PF00939.19 EGO24899.1 - 1.4e-34 119.9 26.7 1.9e-34 119.5 26.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EGO24899.1 - 2.4e-31 109.1 45.8 2.1e-28 99.4 25.5 2.0 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 EGO24899.1 - 3.5e-31 109.5 9.0 5.9e-22 79.1 1.3 2.1 1 1 1 2 2 2 2 SPX domain PBP1_TM PF14812.6 EGO24899.1 - 0.35 11.3 7.8 1.1 9.6 7.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3585 PF12130.8 EGO24900.1 - 0.0064 16.6 0.1 0.014 15.5 0.1 1.5 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain TolA_bind_tri PF16331.5 EGO24900.1 - 0.025 14.7 1.2 0.12 12.5 0.5 2.2 2 1 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 EGO24900.1 - 0.099 13.3 2.3 4.8 7.9 1.9 2.5 2 0 0 2 2 2 0 SlyX CCDC-167 PF15188.6 EGO24900.1 - 0.11 12.9 3.2 0.2 12.0 3.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 HSBP1 PF06825.12 EGO24900.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Med2 PF11214.8 EGO24900.1 - 0.19 11.9 1.4 0.36 11.0 1.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 zf-C3HC4_3 PF13920.6 EGO24901.1 - 6e-07 29.2 10.1 2.3e-06 27.4 10.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO24901.1 - 1.6e-06 27.9 9.5 2.9e-06 27.1 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO24901.1 - 1.5e-05 24.8 8.1 2.9e-05 24.0 8.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGO24901.1 - 0.00013 22.2 10.0 0.00024 21.4 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO24901.1 - 0.00021 21.2 5.3 0.00021 21.2 5.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO24901.1 - 0.00061 19.6 9.6 0.0032 17.3 9.7 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGO24901.1 - 0.012 15.4 5.7 0.012 15.4 5.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO24901.1 - 3.1 8.0 12.0 37 4.6 12.4 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING COPIIcoated_ERV PF07970.12 EGO24902.1 - 3.4e-38 131.7 0.9 5.1e-38 131.1 0.9 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGO24902.1 - 1.9e-22 79.4 0.0 4.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pre-SET PF05033.16 EGO24903.1 - 9e-15 55.3 5.3 9e-15 55.3 5.3 2.1 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 EGO24903.1 - 2.5e-14 54.0 0.1 2.5e-14 54.0 0.1 2.2 2 1 0 2 2 2 1 SET domain F-box-like PF12937.7 EGO24905.1 - 1.1e-14 54.0 2.7 2.4e-07 30.5 0.6 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EGO24905.1 - 0.026 14.4 3.1 0.54 10.2 0.2 2.8 2 1 0 2 2 2 0 F-box domain FPN1 PF06963.12 EGO24908.1 - 5.1e-125 417.4 18.1 6.1e-125 417.2 18.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) F-box-like PF12937.7 EGO24909.1 - 6.2e-07 29.2 0.3 2.7e-06 27.1 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 EGO24909.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 EGO24910.1 - 1.9e-08 34.1 0.6 6.1e-08 32.4 0.6 2.0 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.21 EGO24913.1 - 1.7e-90 303.8 0.0 2e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_assoc PF14363.6 EGO24914.1 - 0.021 15.1 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF5642 PF18702.1 EGO24915.1 - 0.011 15.5 0.2 0.012 15.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) CREPT PF16566.5 EGO24916.1 - 0.0065 16.7 7.2 0.0065 16.7 7.2 3.2 1 1 2 3 3 3 2 Cell-cycle alteration and expression-elevated protein in tumour DUF5082 PF16888.5 EGO24916.1 - 0.008 16.5 5.0 0.008 16.5 5.0 3.1 2 2 1 3 3 3 2 Domain of unknown function (DUF5082) DivIC PF04977.15 EGO24916.1 - 0.27 11.0 15.8 0.31 10.8 1.4 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 EGO24916.1 - 5.8 7.0 12.2 8.9 6.4 3.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APH PF01636.23 EGO24917.1 - 2e-06 27.9 0.0 2.9e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4436 PF14494.6 EGO24918.1 - 3.7e-10 39.5 3.7 3.7e-10 39.5 3.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) DUF4436 PF14494.6 EGO24919.1 - 7.7e-07 28.7 1.2 8.8e-07 28.5 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) ATP-synt_8 PF00895.20 EGO24919.1 - 0.075 13.5 1.2 9.8 6.7 0.6 2.4 2 1 0 2 2 2 0 ATP synthase protein 8 MFS_1 PF07690.16 EGO24920.1 - 1.3e-32 113.2 19.1 1.3e-32 113.2 19.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO24920.1 - 5.4e-07 28.4 1.1 1e-06 27.5 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO24920.1 - 8.2e-05 21.6 16.6 0.00023 20.2 16.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter COesterase PF00135.28 EGO24921.1 - 3.5e-155 517.8 1.7 4.4e-80 270.0 0.2 2.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO24921.1 - 3.1e-10 40.3 11.7 0.00028 20.8 5.1 3.7 2 2 0 2 2 2 2 alpha/beta hydrolase fold PsbI PF02532.14 EGO24921.1 - 3.3 7.7 6.7 46 4.1 0.3 3.8 4 0 0 4 4 4 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) COesterase PF00135.28 EGO24922.1 - 5.7e-75 253.1 1.2 1.6e-74 251.7 1.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO24922.1 - 1.3e-05 25.2 2.3 8.1e-05 22.6 2.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO24922.1 - 0.02 14.4 0.3 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L30 PF00327.20 EGO24924.1 - 1.1e-10 41.2 0.4 2e-10 40.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CENP_C_N PF15622.6 EGO24924.1 - 0.032 13.7 0.0 0.037 13.5 0.0 1.0 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Abhydrolase_6 PF12697.7 EGO24925.1 - 1.6e-21 77.9 0.6 2.3e-21 77.4 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO24925.1 - 9.8e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO24925.1 - 6.1e-05 22.8 0.0 0.0015 18.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EGO24925.1 - 0.00023 21.3 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain AAA PF00004.29 EGO24926.1 - 7.8e-94 311.1 0.0 2.4e-47 160.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO24926.1 - 1.6e-22 79.1 0.8 3.4e-11 42.7 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGO24926.1 - 1.7e-15 57.1 0.0 5e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGO24926.1 - 2.7e-14 53.6 0.8 0.025 14.9 0.0 5.4 2 2 3 5 5 5 3 AAA domain AAA_16 PF13191.6 EGO24926.1 - 2.4e-13 50.8 1.2 0.0015 18.9 0.1 4.6 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 EGO24926.1 - 2.8e-10 40.3 0.5 0.0024 17.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGO24926.1 - 3.7e-10 40.1 0.0 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EGO24926.1 - 5.8e-10 39.6 0.0 0.00075 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGO24926.1 - 5e-09 35.8 0.0 7.4e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EGO24926.1 - 3.8e-08 33.7 0.0 0.014 15.8 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGO24926.1 - 1.1e-07 31.9 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGO24926.1 - 5e-07 29.3 0.9 0.032 13.6 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGO24926.1 - 5.6e-07 29.5 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EGO24926.1 - 1.7e-06 28.4 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGO24926.1 - 4.9e-06 26.6 0.9 0.1 12.5 0.0 3.7 3 1 1 4 4 4 2 NACHT domain ABC_tran PF00005.27 EGO24926.1 - 6.8e-06 26.6 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 EGO24926.1 - 9.5e-06 25.6 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGO24926.1 - 1.5e-05 25.5 0.0 0.3 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 EGO24926.1 - 2.3e-05 24.6 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.11 EGO24926.1 - 2.7e-05 24.0 0.0 0.057 13.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGO24926.1 - 3.5e-05 24.3 0.0 0.082 13.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 EGO24926.1 - 4.1e-05 23.3 1.1 2.6 7.6 0.0 4.3 3 1 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 EGO24926.1 - 4.6e-05 23.2 0.0 0.45 10.2 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Rad17 PF03215.15 EGO24926.1 - 5.9e-05 23.1 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 EGO24926.1 - 6.5e-05 22.3 0.0 0.43 9.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 EGO24926.1 - 6.6e-05 22.4 0.1 1.1 8.6 0.0 3.1 2 1 1 3 3 3 2 KaiC AAA_7 PF12775.7 EGO24926.1 - 0.00011 21.8 0.0 0.64 9.5 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 EGO24926.1 - 0.00016 21.0 0.0 0.0061 15.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EGO24926.1 - 0.0002 21.5 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EGO24926.1 - 0.00022 21.0 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EGO24926.1 - 0.00029 20.1 0.0 0.94 8.6 0.0 2.6 2 1 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.6 EGO24926.1 - 0.0011 18.8 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EGO24926.1 - 0.0014 17.8 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EGO24926.1 - 0.0024 17.9 0.0 2.1 8.2 0.0 2.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGO24926.1 - 0.0024 17.6 0.0 0.94 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EGO24926.1 - 0.0034 16.8 0.2 2.3 7.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein SKI PF01202.22 EGO24926.1 - 0.0035 17.5 0.0 3.6 7.7 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase NTPase_1 PF03266.15 EGO24926.1 - 0.02 14.8 0.0 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 NTPase AFG1_ATPase PF03969.16 EGO24926.1 - 0.022 13.7 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 EGO24926.1 - 0.022 14.6 0.0 4.7 7.0 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2075 PF09848.9 EGO24926.1 - 0.023 13.9 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.10 EGO24926.1 - 0.032 14.2 0.0 9.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 EGO24926.1 - 0.06 13.7 0.9 18 5.7 0.2 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGO24926.1 - 0.061 13.1 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGO24926.1 - 0.083 12.3 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CPT PF07931.12 EGO24926.1 - 0.17 11.7 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.16 EGO24926.1 - 0.18 11.1 0.1 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase PTCB-BRCT PF12738.7 EGO24927.1 - 1.6e-35 120.8 0.0 1e-13 51.0 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EGO24927.1 - 1.8e-21 76.3 0.0 1.8e-07 31.5 0.0 4.3 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGO24927.1 - 9.8e-08 32.3 0.0 0.065 13.6 0.0 3.8 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGO24927.1 - 7.4e-05 23.0 0.0 0.17 12.2 0.0 3.7 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Get5_C PF18514.1 EGO24928.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Get5 C-terminal domain CK_II_beta PF01214.18 EGO24929.1 - 2.1e-79 265.6 0.0 2.5e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MBOAT PF03062.19 EGO24930.1 - 2.6e-48 165.2 24.1 4.7e-48 164.3 24.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FAD_binding_3 PF01494.19 EGO24931.1 - 3.7e-14 52.7 0.2 4.6e-13 49.1 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO24931.1 - 1.1e-08 35.1 2.5 1.4e-08 34.8 0.7 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO24931.1 - 1e-07 31.4 1.5 1.8e-07 30.6 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO24931.1 - 2.8e-07 30.4 7.0 5.8e-05 22.8 4.8 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO24931.1 - 1.1e-06 28.2 0.9 0.00021 20.6 0.5 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO24931.1 - 1.1e-06 28.3 0.1 1.5e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO24931.1 - 1.2e-06 27.5 0.4 2.7e-06 26.4 0.4 1.5 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGO24931.1 - 0.0001 21.7 1.7 0.00094 18.5 1.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO24931.1 - 0.00074 18.9 1.9 0.42 9.8 0.9 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EGO24931.1 - 0.0026 16.9 0.7 0.45 9.5 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EGO24931.1 - 0.0027 18.2 1.3 0.021 15.4 0.9 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO24931.1 - 0.0072 15.6 0.3 0.013 14.8 0.3 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGO24931.1 - 0.023 13.8 1.7 0.053 12.6 1.7 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO24931.1 - 0.059 12.2 0.5 0.76 8.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HSP20 PF00011.21 EGO24933.1 - 1.8e-21 76.2 0.1 2.3e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO24933.1 - 2.2e-06 27.1 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 EGO24933.1 - 0.00042 20.6 0.2 0.024 14.9 0.1 2.3 2 0 0 2 2 2 1 BON domain Rib PF08428.10 EGO24933.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat HMA PF00403.26 EGO24933.1 - 0.039 14.4 0.1 0.58 10.6 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain ARA70 PF12489.8 EGO24934.1 - 0.038 14.2 0.6 0.074 13.2 0.1 1.6 2 1 0 2 2 2 0 Nuclear coactivator TACI-CRD2 PF09305.10 EGO24934.1 - 0.057 13.4 0.8 0.13 12.3 0.8 1.6 1 0 0 1 1 1 0 TACI, cysteine-rich domain Retrotrans_gag PF03732.17 EGO24936.1 - 2.4e-06 27.7 0.3 2.4e-06 27.7 0.3 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Y_phosphatase3 PF13350.6 EGO24938.1 - 1.8e-32 113.2 0.0 1e-26 94.3 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO24938.1 - 4e-05 23.3 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO24938.1 - 5.7e-05 22.8 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGO24938.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EGO24938.1 - 0.0017 18.9 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain PTPlike_phytase PF14566.6 EGO24938.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.14 EGO24938.1 - 0.028 13.4 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glypican PF01153.19 EGO24938.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Glypican Succ_CoA_lig PF13607.6 EGO24938.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Ins_allergen_rp PF06757.13 EGO24938.1 - 0.18 11.8 0.0 0.22 11.5 0.0 1.3 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Y_phosphatase3 PF13350.6 EGO24939.1 - 1.1e-53 182.6 0.0 3.8e-44 151.4 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO24939.1 - 9.4e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO24939.1 - 5.1e-05 23.0 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO24939.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGO24939.1 - 0.0064 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EGO24939.1 - 0.023 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain WD40 PF00400.32 EGO24941.1 - 0.24 12.4 0.1 0.24 12.4 0.1 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat DNA_pol_B PF00136.21 EGO24942.1 - 3.1e-101 339.4 0.0 4.6e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGO24942.1 - 5.5e-22 78.4 0.1 3.8e-10 39.4 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGO24942.1 - 7.8e-15 55.1 3.2 1.7e-14 54.0 3.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EGO24942.1 - 0.16 10.8 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral SET PF00856.28 EGO24943.1 - 2.4e-05 24.8 0.0 0.00016 22.1 0.0 1.9 1 1 0 1 1 1 1 SET domain ArsR PF09824.9 EGO24945.1 - 0.059 13.0 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator APG12 PF04110.13 EGO24946.1 - 0.013 15.9 0.2 2.8 8.4 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Retrotrans_gag PF03732.17 EGO24946.1 - 0.029 14.6 0.2 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein LcrV PF04792.12 EGO24946.1 - 0.15 11.3 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein Mito_fiss_reg PF05308.11 EGO24946.1 - 1.2 9.1 6.4 2.8 8.0 6.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-CCHC PF00098.23 EGO24948.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO24948.1 - 0.0083 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO24948.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain F-box-like PF12937.7 EGO24950.1 - 2.4e-05 24.1 2.1 0.087 12.7 0.5 2.6 2 0 0 2 2 2 2 F-box-like APAF1_C PF17908.1 EGO24950.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 APAF-1 helical domain p450 PF00067.22 EGO24952.1 - 4.6e-57 193.8 0.0 1.4e-55 188.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF4328 PF14219.6 EGO24952.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF4470 PF14737.6 EGO24953.1 - 8.3e-20 70.8 0.0 3.8e-19 68.7 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_12 PF13424.6 EGO24953.1 - 6.3e-16 58.4 9.7 8.1e-05 22.8 0.3 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.22 EGO24953.1 - 4.4e-09 35.9 0.1 7.9e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 EGO24953.1 - 7.6e-08 31.9 11.9 0.2 11.9 1.3 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.6 EGO24953.1 - 4.1e-05 23.1 5.2 0.018 14.5 0.5 4.0 2 1 2 4 4 4 1 Soluble NSF attachment protein, SNAP NACHT PF05729.12 EGO24953.1 - 0.00013 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_1 PF00515.28 EGO24953.1 - 0.00067 19.4 9.8 0.26 11.2 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 EGO24953.1 - 0.0043 17.5 3.6 0.053 13.9 0.2 3.8 3 1 0 3 3 2 1 AAA ATPase domain TPR_8 PF13181.6 EGO24953.1 - 0.0044 17.1 1.3 0.32 11.3 0.6 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24953.1 - 0.0064 16.5 1.5 0.11 12.6 0.6 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA PF00004.29 EGO24953.1 - 0.0074 16.7 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.6 EGO24953.1 - 0.013 15.4 7.6 1.6 8.7 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO24953.1 - 0.017 15.4 3.6 1.2 9.5 0.0 3.7 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 COG5 PF10392.9 EGO24953.1 - 0.035 14.3 0.5 0.095 12.9 0.5 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Elong_Iki1 PF10483.9 EGO24953.1 - 0.069 12.6 0.2 0.16 11.4 0.2 1.5 1 0 0 1 1 1 0 Elongator subunit Iki1 TPR_16 PF13432.6 EGO24953.1 - 0.13 12.9 8.8 1.6 9.4 1.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO24953.1 - 1.2 8.8 4.8 2.7 7.8 0.3 3.5 3 1 1 4 4 4 0 TPR repeat DUF4381 PF14316.6 EGO24956.1 - 0.2 11.9 0.3 0.22 11.7 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RNase_P_Rpp14 PF01900.19 EGO24957.1 - 1.6e-30 105.4 0.1 2e-30 105.1 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Raffinose_syn PF05691.12 EGO24957.1 - 0.0024 15.7 0.0 0.0026 15.7 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 BshC PF10079.9 EGO24960.1 - 0.18 10.5 16.2 0.24 10.1 16.2 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PRTP PF01366.18 EGO24960.1 - 0.21 9.6 6.5 0.26 9.3 5.7 1.5 1 1 0 1 1 1 0 Herpesvirus processing and transport protein Exonuc_VII_L PF02601.15 EGO24960.1 - 1.1 8.8 10.2 1.6 8.2 10.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GRIM-19 PF06212.12 EGO24960.1 - 5 7.1 9.1 0.62 10.0 0.6 2.6 1 1 1 2 2 2 0 GRIM-19 protein DUF4139 PF13598.6 EGO24962.1 - 0.024 14.3 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4139) SSF PF00474.17 EGO24963.1 - 2.2e-19 69.6 28.3 4e-19 68.8 28.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family NPCC PF08058.11 EGO24963.1 - 4.8 7.3 4.7 2.7 8.1 0.5 2.7 3 0 0 3 3 3 0 Nuclear pore complex component FmdA_AmdA PF03069.15 EGO24964.1 - 3.1e-143 477.2 0.0 3.8e-143 476.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Sdh_cyt PF01127.22 EGO24965.1 - 6.7e-24 84.3 0.8 8.2e-24 84.0 0.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PXA PF02194.15 EGO24968.1 - 1.5e-43 148.9 1.6 7.5e-43 146.6 0.4 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 EGO24968.1 - 1.9e-28 99.2 0.4 7.1e-28 97.4 0.1 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EGO24968.1 - 5.1e-18 65.1 0.0 2.1e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 EGO24968.1 - 8.4e-09 35.7 0.1 1.9e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain ParB PF08775.10 EGO24968.1 - 0.022 15.2 0.2 0.094 13.2 0.2 2.1 1 0 0 1 1 1 0 ParB family DUF5493 PF17597.2 EGO24968.1 - 0.096 13.0 0.9 30 5.0 1.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5493) ABC_tran_CTD PF16326.5 EGO24968.1 - 0.13 12.5 1.5 0.4 11.0 1.5 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain PBP1_TM PF14812.6 EGO24968.1 - 6 7.3 9.1 1 9.8 4.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hce2 PF14856.6 EGO24970.1 - 0.00013 22.2 0.6 0.00018 21.7 0.6 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DHFR_2 PF06442.11 EGO24970.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 R67 dihydrofolate reductase Amidase PF01425.21 EGO24971.1 - 3.3e-103 346.1 0.0 4e-103 345.8 0.0 1.1 1 0 0 1 1 1 1 Amidase LRR_4 PF12799.7 EGO24972.1 - 0.76 10.3 8.8 1.4 9.5 1.4 4.1 2 1 4 6 6 6 0 Leucine Rich repeats (2 copies) RabGAP-TBC PF00566.18 EGO24973.1 - 2.5e-49 167.8 0.0 5.9e-49 166.6 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MAT1 PF06391.13 EGO24973.1 - 0.056 13.3 1.5 0.13 12.1 1.5 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 COX6B PF02297.17 EGO24974.1 - 9.7e-22 77.0 3.3 1.3e-21 76.6 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EGO24974.1 - 0.012 15.9 2.4 0.11 12.8 2.4 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 EGO24974.1 - 0.051 13.8 2.7 0.11 12.7 2.2 1.9 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein QueF_N PF14819.6 EGO24975.1 - 0.18 12.1 0.7 22 5.4 0.1 2.4 1 1 1 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term TPR_1 PF00515.28 EGO24976.1 - 6.2e-12 44.8 4.3 0.0029 17.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO24976.1 - 8.1e-11 41.2 4.7 0.00033 20.5 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO24976.1 - 1.6e-07 31.7 0.3 2.3e-06 28.0 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO24976.1 - 4.6e-06 26.2 0.9 0.0012 18.4 0.3 2.9 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 EGO24976.1 - 1.2e-05 25.9 4.9 1.2e-05 25.8 0.1 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO24976.1 - 5.9e-05 23.0 0.3 0.33 11.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO24976.1 - 0.00013 22.5 4.3 0.14 13.0 0.1 3.7 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO24976.1 - 0.00013 21.8 0.7 0.051 13.6 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO24976.1 - 0.00049 20.3 4.3 0.63 10.4 0.8 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO24976.1 - 0.0036 17.5 0.3 0.0089 16.2 0.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGO24976.1 - 0.0098 15.1 0.3 0.028 13.7 0.3 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO24976.1 - 0.012 16.2 6.7 0.83 10.4 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO24976.1 - 0.027 14.6 0.3 7.4 6.8 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO24976.1 - 0.034 14.2 0.7 16 5.7 0.0 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGO24976.1 - 0.3 11.0 5.3 0.49 10.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 EGO24977.1 - 4e-09 36.1 0.0 4.9e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGO24977.1 - 2.6e-06 27.2 0.0 3.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGO24977.1 - 7.9e-06 26.6 0.1 2e-05 25.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 EGO24977.1 - 0.00083 19.1 0.0 0.0024 17.5 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EGO24977.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EGO24977.1 - 0.028 13.1 0.0 0.046 12.4 0.0 1.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1749 PF08538.10 EGO24977.1 - 0.23 10.5 0.0 2.8 7.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) MFS_1 PF07690.16 EGO24979.1 - 2e-26 92.8 29.1 2.7e-19 69.3 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO24979.1 - 2.6e-17 62.8 16.2 4.1e-16 58.9 16.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Arrestin_N PF00339.29 EGO24980.1 - 5.3e-06 26.5 0.0 1.8e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGO24980.1 - 3.9e-05 24.1 0.0 0.0011 19.5 0.0 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Glyco_transf_8 PF01501.20 EGO24981.1 - 3.5e-24 85.7 0.0 1.8e-23 83.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 EGO24981.1 - 9.2e-18 65.2 0.0 4.8e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 EGO24981.1 - 7.6e-08 32.1 0.0 1.6e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Glucosyltransferase 24 Methyltransf_3 PF01596.17 EGO24981.1 - 0.0018 17.5 0.0 0.0043 16.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Glyco_trans_4_4 PF13579.6 EGO24981.1 - 0.0025 18.3 0.8 0.0062 17.0 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Epimerase PF01370.21 EGO24982.1 - 3e-15 56.4 0.0 5.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.26 EGO24982.1 - 2.3e-14 53.5 0.0 4.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 GDP_Man_Dehyd PF16363.5 EGO24982.1 - 3.1e-05 23.6 0.0 0.099 12.0 0.0 2.2 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Glyco_tranf_2_3 PF13641.6 EGO24982.1 - 4.4e-05 23.5 0.1 0.0001 22.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGO24982.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DBR1 PF05011.13 EGO24983.1 - 1.2e-43 148.9 0.0 1.7e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGO24983.1 - 3.7e-09 37.4 1.2 5.5e-09 36.8 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO24983.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SSF PF00474.17 EGO24984.1 - 7.6e-21 74.4 32.9 7.6e-21 74.4 32.9 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family MINDY_DUB PF04424.13 EGO24986.1 - 2.9e-27 95.0 0.0 7.9e-27 93.6 0.0 1.8 2 0 0 2 2 2 1 MINDY deubiquitinase Herpes_UL32 PF06070.11 EGO24986.1 - 0.1 10.3 1.4 0.15 9.8 1.4 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 eIF-3_zeta PF05091.12 EGO24986.1 - 0.32 9.9 5.8 0.47 9.4 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) U79_P34 PF03064.16 EGO24986.1 - 1.7 8.0 11.0 3 7.2 11.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Uricase PF01014.18 EGO24990.1 - 1.4e-68 229.1 0.1 4.4e-35 120.8 0.1 2.0 2 0 0 2 2 2 2 Uricase Lyase_1 PF00206.20 EGO24991.1 - 2.8e-120 401.4 0.0 3.7e-120 401.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGO24991.1 - 1.4e-19 70.3 0.1 2.9e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EGO24991.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-CCHC PF00098.23 EGO24992.1 - 6.2e-12 45.0 13.2 1.6e-07 31.0 5.9 2.3 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.17 EGO24992.1 - 1.8e-08 34.5 1.7 1.8e-08 34.5 1.7 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO24992.1 - 0.0036 17.2 9.6 0.048 13.6 2.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGO24992.1 - 0.005 16.5 6.6 0.27 11.0 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle Musclin PF11037.8 EGO24992.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle zf-CCHC_5 PF14787.6 EGO24992.1 - 1.8 8.3 8.6 2.8 7.7 1.0 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EGO24992.1 - 3.7 7.5 8.2 10 6.0 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle MULE PF10551.9 EGO24993.1 - 0.0055 17.1 1.4 0.0096 16.3 0.1 2.2 2 1 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EGO24993.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Transposase Ocnus PF05005.15 EGO24993.1 - 0.12 12.5 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) gag-asp_proteas PF13975.6 EGO24994.1 - 1.8e-06 28.4 0.0 2.8e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO24994.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO24994.1 - 0.00013 22.6 0.0 0.00022 21.8 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease Pollen_Ole_e_I PF01190.17 EGO24994.1 - 0.0024 18.2 0.2 0.21 12.0 0.0 2.0 1 1 1 2 2 2 1 Pollen proteins Ole e I like Asp_protease PF09668.10 EGO24994.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 EGO24997.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGO24997.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO24997.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGO24997.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO24997.1 - 0.0054 16.7 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO24997.1 - 0.032 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family ubiquitin PF00240.23 EGO24998.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family RGP PF03214.13 EGO25000.1 - 0.061 12.5 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Retrotrans_gag PF03732.17 EGO25004.1 - 6.4e-08 32.8 0.2 6.4e-08 32.8 0.2 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein DDE_Tnp_ISL3 PF01610.17 EGO25005.1 - 0.0025 17.5 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 Transposase MULE PF10551.9 EGO25005.1 - 0.0055 17.1 1.0 0.014 15.8 0.1 2.2 2 1 0 2 2 2 1 MULE transposase domain DUF1462 PF07315.11 EGO25006.1 - 0.059 13.7 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) ubiquitin PF00240.23 EGO25006.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 EGO25007.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGO25007.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO25007.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGO25007.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO25007.1 - 0.0054 16.7 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO25007.1 - 0.032 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Sec63 PF02889.16 EGO25011.1 - 1.3e-10 40.9 0.0 1.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Ubiquitin_4 PF18036.1 EGO25017.1 - 8.1e-05 22.6 0.1 0.99 9.5 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-like domain ubiquitin PF00240.23 EGO25017.1 - 0.019 14.7 0.5 4 7.3 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin family USP7_C2 PF14533.6 EGO25017.1 - 0.14 11.8 0.8 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-specific protease C-terminal T4-Gluco-transf PF09198.10 EGO25017.1 - 0.73 9.5 2.9 28 4.4 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase zf-CCHC PF00098.23 EGO25021.1 - 0.00043 20.2 1.8 0.00072 19.5 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1181 PF06680.11 EGO25023.1 - 0.069 13.0 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) CHAT PF12770.7 EGO25026.1 - 2.2e-16 60.1 0.8 2e-14 53.7 0.8 2.5 1 1 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EGO25026.1 - 4e-10 39.2 1.0 0.0082 16.0 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25026.1 - 1.5e-08 34.8 22.9 3.1 8.2 0.0 10.0 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGO25026.1 - 1.3e-06 28.0 4.4 5.8 7.2 0.1 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO25026.1 - 0.00073 19.3 11.1 8.3 6.4 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25026.1 - 0.0096 16.1 2.2 31 5.1 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat C2 PF00168.30 EGO25026.1 - 0.019 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 C2 domain MFS_1 PF07690.16 EGO25027.1 - 2.7e-39 135.1 53.6 3.6e-29 101.8 15.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1391 PF07151.12 EGO25027.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Cpn10 PF00166.21 EGO25028.1 - 2.7e-27 94.6 0.0 3.2e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-MYND PF01753.18 EGO25029.1 - 5.7e-08 32.7 13.1 1.1e-07 31.8 13.1 1.5 1 0 0 1 1 1 1 MYND finger Sugar_tr PF00083.24 EGO25030.1 - 0.049 12.5 4.5 0.059 12.2 4.5 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 EGO25031.1 - 6.2e-13 48.4 25.7 2.8e-08 33.1 12.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3930 PF13067.6 EGO25031.1 - 0.85 9.9 4.0 0.23 11.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) Sugar_tr PF00083.24 EGO25033.1 - 5.7e-102 341.9 20.1 6.5e-102 341.7 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO25033.1 - 2.3e-24 86.0 44.5 3.4e-16 59.1 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Thg1 PF04446.12 EGO25035.1 - 3.4e-48 162.8 0.0 5e-48 162.3 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGO25035.1 - 1.3e-45 154.5 0.1 2.1e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain CDC45 PF02724.14 EGO25036.1 - 0.46 8.7 1.2 0.51 8.6 1.2 1.0 1 0 0 1 1 1 0 CDC45-like protein UCH PF00443.29 EGO25037.1 - 2.3e-50 171.5 0.1 3.1e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO25037.1 - 1.1e-18 67.9 1.1 2e-17 63.8 1.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2701 PF10857.8 EGO25040.1 - 0.63 10.1 4.1 0.88 9.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) RVP_2 PF08284.11 EGO25041.1 - 4.9e-09 36.1 0.0 5.3e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO25041.1 - 7.2e-08 32.9 0.0 8.3e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO25041.1 - 2e-05 25.1 0.0 2.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 EGO25041.1 - 0.00089 19.3 0.0 0.00097 19.2 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon peptidase APH PF01636.23 EGO25042.1 - 6.7e-06 26.2 0.1 3.8e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Nop14 PF04147.12 EGO25044.1 - 3 5.9 5.7 4.7 5.3 5.7 1.2 1 0 0 1 1 1 0 Nop14-like family LpoB PF13036.6 EGO25045.1 - 0.087 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB CHAT PF12770.7 EGO25046.1 - 2.4e-31 109.3 0.0 3.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EGO25046.1 - 4.2e-12 45.5 20.6 0.31 11.0 0.0 11.7 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25046.1 - 1.3e-08 35.0 25.4 2.4 8.5 0.1 13.3 9 4 5 14 14 14 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGO25046.1 - 7.3e-08 32.6 1.1 23 6.2 0.0 8.2 8 0 0 8 8 8 0 Tetratricopeptide repeat C2 PF00168.30 EGO25046.1 - 0.00057 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain TPR_17 PF13431.6 EGO25046.1 - 0.00068 19.8 8.9 0.83 10.2 0.1 6.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25046.1 - 0.024 14.8 5.8 69 4.0 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat T3SSipB PF16535.5 EGO25046.1 - 0.025 15.1 2.9 7 7.1 0.0 3.7 3 0 0 3 3 3 0 Type III cell invasion protein SipB TPR_16 PF13432.6 EGO25046.1 - 0.56 10.9 5.2 29 5.4 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25046.1 - 0.69 10.2 10.7 62 4.1 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat NUDIX PF00293.28 EGO25048.1 - 6.1e-24 84.5 0.0 8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Mito_carr PF00153.27 EGO25049.1 - 8.3e-33 112.2 2.3 5.8e-15 55.0 0.1 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein RAI1 PF08652.11 EGO25052.1 - 3.8e-21 75.0 0.0 7.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease SUR7 PF06687.12 EGO25053.1 - 7.1e-13 48.7 20.8 2.1e-08 34.1 1.6 2.1 1 1 1 2 2 2 2 SUR7/PalI family Amastin PF07344.11 EGO25053.1 - 0.22 11.4 5.6 0.37 10.6 3.7 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein GATA PF00320.27 EGO25060.1 - 7.7e-16 57.4 3.0 1.7e-15 56.3 3.0 1.6 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.9 EGO25060.1 - 0.72 8.3 3.4 0.85 8.1 3.4 1.1 1 0 0 1 1 1 0 Macoilin family GKAP PF03359.13 EGO25060.1 - 0.93 9.0 7.0 1.9 8.0 6.9 1.4 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein Dicty_REP PF05086.12 EGO25060.1 - 2 6.3 3.3 2.2 6.1 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4955 PF16315.5 EGO25061.1 - 0.032 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) TauD PF02668.16 EGO25063.1 - 5.2e-58 197.0 0.3 6.4e-58 196.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyt-b5 PF00173.28 EGO25064.1 - 1.5e-19 69.9 0.0 2.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cupin_1 PF00190.22 EGO25065.1 - 2.6e-41 140.7 0.1 1.7e-19 69.9 0.1 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGO25065.1 - 2.1e-27 94.6 0.3 1.3e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGO25065.1 - 3.5e-10 39.4 0.0 0.00044 19.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EGO25065.1 - 5.8e-09 36.0 0.2 5.5e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EGO25065.1 - 5.9e-05 23.0 0.0 0.00032 20.6 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 EGO25065.1 - 0.00031 20.4 0.0 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase CENP-C_C PF11699.8 EGO25065.1 - 0.00037 20.6 0.0 0.69 10.2 0.0 2.6 2 1 0 2 2 2 2 Mif2/CENP-C like Cupin_4 PF08007.12 EGO25065.1 - 0.01 15.3 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein cNMP_binding PF00027.29 EGO25065.1 - 0.092 12.8 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain ARD PF03079.14 EGO25065.1 - 0.11 12.7 0.1 7 6.8 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family GMC_oxred_N PF00732.19 EGO25066.1 - 1e-64 218.8 0.0 1.4e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO25066.1 - 5e-34 117.9 0.0 9.8e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO25066.1 - 0.00012 21.3 0.4 0.00028 20.1 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO25066.1 - 0.0039 16.3 0.4 1.4 7.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGO25066.1 - 0.01 15.5 0.3 2 7.9 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGO25066.1 - 0.024 13.9 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EGO25066.1 - 0.027 14.7 0.1 0.074 13.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Cu-oxidase PF00394.22 EGO25067.1 - 2.1e-45 154.7 0.0 4.2e-43 147.2 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO25067.1 - 9.4e-38 129.0 2.4 4.5e-35 120.3 0.0 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO25067.1 - 1.4e-37 128.3 0.9 2.1e-34 118.1 0.9 3.3 3 0 0 3 3 3 1 Multicopper oxidase Pheromone PF08015.11 EGO25068.1 - 0.067 14.2 3.0 0.5 11.5 3.0 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone Pheromone PF08015.11 EGO25069.1 - 0.028 15.5 5.1 0.47 11.5 5.1 2.1 1 1 0 1 1 1 0 Fungal mating-type pheromone RasGAP PF00616.19 EGO25070.1 - 1.7e-59 201.1 0.3 4.3e-58 196.4 0.0 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGO25070.1 - 5.4e-36 123.7 0.7 1.7e-35 122.2 0.7 1.9 1 0 0 1 1 1 1 RasGAP C-terminus Glyco_trans_1_3 PF13528.6 EGO25071.1 - 0.14 11.4 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 1 Aa_trans PF01490.18 EGO25072.1 - 2e-87 293.6 28.9 2.4e-87 293.3 28.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 EGO25072.1 - 0.23 11.5 1.3 1 9.5 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized YmpT-like Fungal_lectin PF07938.12 EGO25074.1 - 4.6e-11 42.7 0.4 7.8e-11 41.9 0.4 1.4 1 0 0 1 1 1 1 Fungal fucose-specific lectin CBM_1 PF00734.18 EGO25074.1 - 9.6e-09 35.1 8.5 9.6e-09 35.1 8.5 1.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Fucose_iso_N1 PF07881.12 EGO25074.1 - 0.071 13.0 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 L-fucose isomerase, first N-terminal domain DUF1392 PF07154.11 EGO25075.1 - 0.19 11.8 0.0 0.7 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1392) eIF3_subunit PF08597.10 EGO25076.1 - 1.7e-57 195.2 21.7 1.9e-57 195.0 21.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4192 PF13830.6 EGO25076.1 - 0.1 12.7 2.4 0.14 12.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) WD40 PF00400.32 EGO25077.1 - 3.6e-15 56.1 7.3 0.00064 20.5 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO25077.1 - 0.0029 17.9 0.2 1.7 9.0 0.5 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO25077.1 - 0.071 11.7 0.0 0.49 9.0 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 VSP PF03302.13 EGO25078.1 - 0.003 16.5 7.0 0.0041 16.0 7.0 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3149 PF11346.8 EGO25078.1 - 0.14 11.8 1.2 0.22 11.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Podoplanin PF05808.11 EGO25078.1 - 0.16 12.1 13.6 0.08 13.0 10.2 2.0 2 0 0 2 2 2 0 Podoplanin Ndc1_Nup PF09531.10 EGO25078.1 - 0.73 8.5 5.0 0.93 8.1 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF202 PF02656.15 EGO25079.1 - 1.1e-12 48.2 4.2 1.1e-12 48.2 4.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF5084 PF16894.5 EGO25079.1 - 0.017 15.6 0.8 0.025 15.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) DUF4383 PF14325.6 EGO25079.1 - 0.043 14.1 0.8 0.08 13.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) Insulin_TMD PF17870.1 EGO25079.1 - 0.19 11.8 1.5 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4131 PF13567.6 EGO25079.1 - 2.6 7.7 6.4 9 5.9 6.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Pro_isomerase PF00160.21 EGO25081.1 - 3.4e-46 157.4 0.0 3.9e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F_actin_cap_B PF01115.17 EGO25082.1 - 2.6e-108 361.2 0.0 3e-108 361.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit PsiB PF06290.11 EGO25082.1 - 0.0039 16.7 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Plasmid SOS inhibition protein (PsiB) Pkinase PF00069.25 EGO25084.1 - 4.1e-42 144.4 0.0 1.3e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25084.1 - 7.3e-20 71.3 0.0 9.3e-10 38.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO25084.1 - 0.00028 20.3 0.0 0.062 12.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGO25084.1 - 0.024 14.5 0.3 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family RNB PF00773.19 EGO25085.1 - 2.9e-52 178.0 0.0 9.5e-52 176.3 0.0 1.8 1 1 0 1 1 1 1 RNB domain RNase_PH PF01138.21 EGO25086.1 - 1.2e-33 116.4 0.1 4.1e-33 114.7 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGO25086.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.17 EGO25087.1 - 3.5e-54 182.9 0.0 4.5e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGO25087.1 - 7.2e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO25087.1 - 0.0076 16.9 0.0 0.025 15.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGO25087.1 - 0.008 15.7 0.0 0.089 12.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGO25087.1 - 0.044 14.5 0.0 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain U1snRNP70_N PF12220.8 EGO25088.1 - 1.4e-25 89.7 0.2 2e-25 89.2 0.2 1.2 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EGO25088.1 - 1.7e-17 63.0 0.0 2.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4799 PF16056.5 EGO25088.1 - 1.8 7.6 6.6 1.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4799) DASH_Dad2 PF08654.10 EGO25089.1 - 3.8e-09 36.9 0.0 5.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 PTSIIB_sorb PF03830.15 EGO25089.1 - 0.0022 18.2 0.0 0.0061 16.8 0.0 1.7 2 0 0 2 2 2 1 PTS system sorbose subfamily IIB component Med12 PF09497.10 EGO25090.1 - 4.4e-27 94.2 0.0 1.4e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EGO25090.1 - 0.00065 18.7 0.0 0.0078 15.1 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain zf-C3HC4_2 PF13923.6 EGO25091.1 - 1.1e-06 28.4 3.6 1.1e-06 28.4 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO25091.1 - 4.1e-06 26.7 3.8 4.1e-06 26.7 3.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGO25091.1 - 2.2e-05 24.7 4.6 2.2e-05 24.7 4.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGO25091.1 - 2.4e-05 24.2 7.9 8.8e-05 22.4 2.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGO25091.1 - 2.5e-05 24.1 0.2 5.7e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 EGO25091.1 - 3.9e-05 23.4 4.3 3.9e-05 23.4 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO25091.1 - 0.0019 18.3 3.4 0.0019 18.3 3.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FlxA PF14282.6 EGO25091.1 - 0.0055 16.7 1.6 0.0055 16.7 1.6 2.4 2 0 0 2 2 2 1 FlxA-like protein zf-C3HC4_3 PF13920.6 EGO25091.1 - 0.0078 16.0 6.5 0.015 15.2 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO25091.1 - 0.0082 16.0 2.1 0.0082 16.0 2.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGO25091.1 - 0.0092 16.2 2.4 0.0092 16.2 2.4 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain ZapB PF06005.12 EGO25091.1 - 0.011 16.1 3.5 0.074 13.5 1.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB ATG16 PF08614.11 EGO25091.1 - 0.012 15.8 1.3 0.023 14.9 1.3 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EGO25091.1 - 0.024 14.4 2.4 0.024 14.4 2.4 1.7 2 0 0 2 2 1 0 Septum formation initiator Trimer_CC PF08954.11 EGO25091.1 - 0.036 13.6 1.3 1.3 8.6 0.8 2.6 2 0 0 2 2 2 0 Trimerisation motif zf-RING_10 PF16685.5 EGO25091.1 - 0.058 13.5 3.2 0.13 12.4 1.3 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EGO25091.1 - 0.17 11.5 8.5 0.072 12.7 4.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EGO25091.1 - 0.25 11.2 3.4 0.64 9.9 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit SlyX PF04102.12 EGO25091.1 - 0.86 10.3 4.1 15 6.3 0.6 3.1 3 0 0 3 3 3 0 SlyX zf-C3HC4_5 PF17121.5 EGO25091.1 - 1.5 8.8 4.4 0.63 10.0 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 EGO25091.1 - 1.6 8.9 6.3 3.7 7.7 0.8 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CEBP_ZZ PF16366.5 EGO25091.1 - 1.9 8.8 7.6 0.24 11.7 3.0 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 EGO25091.1 - 2 8.7 9.4 33 4.8 7.3 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain BTB PF00651.31 EGO25092.1 - 1.8e-06 28.1 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NAD_kinase PF01513.21 EGO25095.1 - 2e-72 243.9 0.0 4.1e-72 242.9 0.0 1.6 1 0 0 1 1 1 1 ATP-NAD kinase Q_salvage PF10343.9 EGO25096.1 - 2.4e-10 40.5 0.0 5e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family YqeY PF09424.10 EGO25097.1 - 2.7e-19 69.6 0.1 3.8e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Yqey-like protein Amidohydro_3 PF07969.11 EGO25098.1 - 2.2e-80 271.4 0.0 2.6e-80 271.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EGO25098.1 - 1.9e-12 47.2 0.0 8.5e-11 41.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family SNF2_N PF00176.23 EGO25099.1 - 6.7e-51 173.0 0.0 4.4e-50 170.4 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO25099.1 - 4.3e-13 49.6 0.0 8.9e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO25099.1 - 2.9e-08 33.9 0.0 6.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO25099.1 - 0.00017 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 EGO25099.1 - 0.082 13.2 0.0 7.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) WD40 PF00400.32 EGO25101.1 - 2.9e-27 94.4 16.1 3.4e-05 24.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO25101.1 - 3.5e-07 30.4 0.1 0.025 14.8 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO25101.1 - 0.00055 19.4 0.0 0.0042 16.5 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain DUF5046 PF16465.5 EGO25101.1 - 0.0012 18.3 0.2 1.7 8.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) PQQ PF01011.21 EGO25101.1 - 0.0012 18.6 0.3 2.8 8.0 0.0 3.8 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 EGO25101.1 - 0.019 15.4 1.3 12 6.5 0.1 3.6 3 0 0 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 EGO25101.1 - 0.022 13.7 0.1 35 3.2 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO25101.1 - 0.056 12.1 0.5 14 4.2 0.0 3.5 2 1 2 5 5 5 0 Nucleoporin Nup120/160 Frtz PF11768.8 EGO25101.1 - 0.093 11.0 0.0 1.3 7.2 0.0 2.2 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz F-box-like PF12937.7 EGO25102.1 - 1.1e-08 34.8 0.3 2.6e-08 33.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO25102.1 - 0.0028 17.5 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain KH_6 PF15985.5 EGO25102.1 - 0.11 12.8 0.2 0.54 10.6 0.1 2.1 2 0 0 2 2 2 0 KH domain DNA_pol3_delta2 PF13177.6 EGO25103.1 - 1.3e-12 47.8 0.1 3.5e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EGO25103.1 - 7.7e-06 26.4 0.2 1.8e-05 25.2 0.2 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EGO25103.1 - 0.00021 21.1 0.2 0.00032 20.5 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGO25103.1 - 0.0022 18.0 0.0 0.0057 16.6 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 EGO25103.1 - 0.0031 17.9 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_16 PF13191.6 EGO25103.1 - 0.0089 16.4 0.3 0.038 14.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO25103.1 - 0.016 15.5 1.4 0.4 11.0 1.0 3.1 1 1 1 2 2 2 0 AAA domain Phyto-Amp PF15438.6 EGO25103.1 - 0.062 13.1 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma AAA_assoc_2 PF16193.5 EGO25103.1 - 0.063 13.6 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA C-terminal domain AAA_33 PF13671.6 EGO25103.1 - 0.099 12.8 0.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO25103.1 - 0.15 11.7 0.4 0.48 10.1 0.4 1.7 1 1 0 1 1 1 0 AAA domain Thiolase_N PF00108.23 EGO25104.1 - 3.9e-66 223.1 0.2 6.1e-66 222.4 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO25104.1 - 1.7e-40 137.5 0.8 1.1e-39 134.9 0.3 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO25104.1 - 0.0003 20.4 0.6 0.0029 17.2 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.12 EGO25104.1 - 0.016 14.5 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein Baculo_RING PF05883.11 EGO25104.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain ACP_syn_III PF08545.10 EGO25104.1 - 0.095 12.6 3.6 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III An_peroxidase PF03098.15 EGO25105.1 - 8.7e-36 123.6 0.1 5.2e-25 88.0 0.1 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EGO25105.1 - 0.00018 20.4 0.0 0.0011 17.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 GMC_oxred_N PF00732.19 EGO25108.1 - 9.1e-05 22.0 0.0 0.00041 19.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DASH_Spc34 PF08657.10 EGO25110.1 - 0.022 14.6 6.5 0.087 12.6 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Spc34 DOCK_N PF16172.5 EGO25112.1 - 2.4e-119 398.6 0.0 3.9e-119 398.0 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EGO25112.1 - 8.9e-75 252.3 0.2 2.6e-74 250.8 0.2 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EGO25112.1 - 3.2e-57 193.5 0.1 4.8e-56 189.7 0.0 2.8 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Med27 PF11571.8 EGO25115.1 - 3.3e-11 43.4 0.0 1.2e-10 41.6 0.0 1.9 2 1 0 2 2 2 1 Mediator complex subunit 27 zf-WRNIP1_ubi PF18279.1 EGO25116.1 - 0.021 15.4 0.7 0.042 14.5 0.7 1.5 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF4177 PF13783.6 EGO25117.1 - 0.13 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Hydrophobin PF01185.18 EGO25118.1 - 1.4e-26 92.9 10.9 1.7e-26 92.6 10.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin LETM1 PF07766.13 EGO25119.1 - 1.8e-25 89.8 1.5 8.1e-15 54.9 0.3 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF3640 PF12342.8 EGO25119.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) TPR_16 PF13432.6 EGO25120.1 - 6e-26 90.8 58.3 9.1e-09 35.8 1.4 10.6 10 1 3 13 13 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGO25120.1 - 3.4e-24 83.6 21.4 0.00012 21.7 0.3 12.0 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25120.1 - 4.5e-22 76.3 41.7 0.00071 19.5 0.3 15.0 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 EGO25120.1 - 1.6e-21 76.6 47.0 0.00035 21.0 1.4 11.3 10 3 4 14 14 13 7 Tetratricopeptide repeat TPR_14 PF13428.6 EGO25120.1 - 7.5e-15 54.4 59.4 0.0053 17.5 0.6 16.9 12 5 6 18 18 17 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25120.1 - 7.9e-15 54.1 21.0 0.0074 16.6 0.1 11.5 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25120.1 - 9.6e-15 53.5 33.0 0.00028 20.9 0.3 13.0 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGO25120.1 - 2.7e-12 46.2 20.6 0.19 11.4 0.4 9.4 7 2 2 9 9 8 5 TPR repeat TPR_12 PF13424.6 EGO25120.1 - 1.1e-08 35.2 55.7 0.003 17.8 1.4 11.8 12 3 2 14 14 12 7 Tetratricopeptide repeat TPR_6 PF13174.6 EGO25120.1 - 2.5e-06 27.8 22.5 10 7.0 0.0 11.5 11 0 0 11 11 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO25120.1 - 2.7e-06 27.5 8.1 0.43 10.8 0.5 7.0 7 1 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 EGO25120.1 - 0.00035 19.4 0.8 0.00035 19.4 0.8 3.3 3 1 1 4 4 4 1 Protein kinase G tetratricopeptide repeat TPR_9 PF13371.6 EGO25120.1 - 0.054 13.6 52.3 2.7 8.2 0.2 11.3 12 1 2 14 14 14 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO25120.1 - 0.45 10.6 4.2 6.7 6.9 0.2 4.5 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGO25120.1 - 1.7 8.8 28.3 1.1 9.5 0.1 8.7 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGO25120.1 - 3.7 7.6 22.1 3.5 7.6 1.9 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGO25120.1 - 3.8 7.9 15.3 0.36 11.2 0.2 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat GST_N_3 PF13417.6 EGO25121.1 - 4.2e-10 39.9 0.0 2.4e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO25121.1 - 3.3e-09 36.9 0.0 8.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGO25121.1 - 0.004 17.5 0.1 0.039 14.3 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO25121.1 - 0.0067 16.6 0.0 0.015 15.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO25121.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGO25121.1 - 0.13 13.0 0.0 0.22 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 EGO25122.1 - 2.5e-11 44.2 0.1 4.6e-11 43.3 0.1 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2694 PF10904.8 EGO25122.1 - 0.21 11.7 0.0 0.5 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) LSM PF01423.22 EGO25124.1 - 4.7e-15 55.0 0.2 6.1e-15 54.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO25124.1 - 0.016 15.4 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain F-box-like PF12937.7 EGO25125.1 - 7.1e-07 29.0 0.2 2.1e-06 27.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like CENP-Q PF13094.6 EGO25125.1 - 0.07 13.3 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 EGO25125.1 - 0.1 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Acetyltransf_3 PF13302.7 EGO25126.1 - 1.9e-05 25.4 0.0 4.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA PF00004.29 EGO25127.1 - 1.9e-20 73.7 0.0 5.4e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO25127.1 - 0.0057 17.0 0.1 0.5 10.7 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGO25127.1 - 0.027 14.5 0.1 0.096 12.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGO25127.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO25127.1 - 0.043 14.2 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO25127.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGO25127.1 - 0.12 12.7 0.1 0.6 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGO25127.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF5587 PF17825.1 EGO25128.1 - 0.19 9.0 0.0 0.22 8.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) Cortex-I_coil PF09304.10 EGO25129.1 - 0.038 14.2 0.8 0.074 13.3 0.3 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil CHAT PF12770.7 EGO25130.1 - 2.5e-22 79.7 0.0 3.7e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EGO25130.1 - 8.1e-08 32.5 15.8 0.19 12.0 0.0 7.7 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25130.1 - 2.2e-06 27.4 2.6 9.4 6.7 0.1 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO25130.1 - 0.00076 19.3 11.5 0.82 9.6 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25130.1 - 0.018 15.1 7.0 46 4.5 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO25130.1 - 0.073 12.9 14.7 8.8 6.3 0.2 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25130.1 - 0.17 12.5 6.7 20 5.9 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EGO25130.1 - 2 9.2 5.6 21 6.0 0.2 5.1 7 0 0 7 7 7 0 Sel1 repeat Arc_C PF18162.1 EGO25131.1 - 0.2 11.5 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Arc C-lobe DMA PF03474.14 EGO25131.1 - 0.22 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 DMRTA motif ABC_membrane PF00664.23 EGO25132.1 - 3e-36 125.5 6.3 3.8e-36 125.1 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGO25132.1 - 4.2e-34 118.0 0.0 7.7e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGO25132.1 - 4.2e-05 23.1 0.2 0.00059 19.3 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGO25132.1 - 0.0015 19.0 1.5 0.0063 16.9 1.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO25132.1 - 0.0019 18.5 0.1 0.023 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGO25132.1 - 0.0029 17.3 0.1 0.026 14.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGO25132.1 - 0.011 15.5 0.1 0.048 13.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGO25132.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EGO25132.1 - 0.044 13.5 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane_2 PF06472.15 EGO25132.1 - 0.088 12.2 2.7 0.18 11.1 2.5 1.6 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 Zeta_toxin PF06414.12 EGO25132.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TMEM191C PF15194.6 EGO25133.1 - 0.072 13.3 0.2 0.095 12.9 0.2 1.2 1 0 0 1 1 1 0 TMEM191C family F-box-like PF12937.7 EGO25135.1 - 3.3e-09 36.5 0.3 7.3e-09 35.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO25135.1 - 5.4e-07 29.3 0.7 1e-06 28.4 0.7 1.4 1 0 0 1 1 1 1 F-box domain Sec_GG PF07549.14 EGO25138.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Cnd1 PF12717.7 EGO25139.1 - 8e-07 29.2 0.2 0.00014 22.0 0.1 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGO25139.1 - 9.1e-06 25.5 0.1 3.2 8.3 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat Pkinase PF00069.25 EGO25139.1 - 0.0001 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25139.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO25139.1 - 0.0088 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Med14 PF08638.11 EGO25140.1 - 5.8e-71 237.9 0.8 1.5e-70 236.5 0.8 1.8 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATP_bind_3 PF01171.20 EGO25141.1 - 4.7e-41 140.6 0.0 7.5e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family OmdA PF13376.6 EGO25141.1 - 0.033 14.2 0.5 0.21 11.7 0.1 2.5 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Spc7 PF08317.11 EGO25141.1 - 0.21 10.5 0.7 0.36 9.7 0.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Acetyltransf_1 PF00583.25 EGO25145.1 - 1.5e-07 31.6 0.0 3.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO25145.1 - 8.7e-06 26.1 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO25145.1 - 1.3e-05 25.1 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 EGO25145.1 - 0.00078 19.4 0.0 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGO25145.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 EGO25145.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGO25145.1 - 0.14 12.3 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO25145.1 - 0.16 12.7 0.0 0.28 11.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4598 PF15370.6 EGO25146.1 - 1.9e-21 76.6 1.5 3.9e-21 75.6 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) BUD22 PF09073.10 EGO25146.1 - 0.32 10.3 9.4 0.34 10.2 9.4 1.1 1 0 0 1 1 1 0 BUD22 DUF515 PF04415.12 EGO25146.1 - 3 6.1 9.8 4 5.7 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PEPCK_ATP PF01293.20 EGO25147.1 - 6.3e-218 724.1 0.0 7.6e-218 723.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EGO25147.1 - 0.014 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO25147.1 - 0.084 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ClpS PF02617.17 EGO25148.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS FAD_binding_3 PF01494.19 EGO25149.1 - 4.3e-67 226.8 0.0 5.3e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGO25149.1 - 0.0025 17.0 0.1 0.0054 15.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO25149.1 - 0.0046 17.2 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO25149.1 - 0.017 14.4 0.0 0.06 12.6 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO25149.1 - 0.028 14.0 0.3 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO25149.1 - 0.037 12.9 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EGO25149.1 - 0.12 11.0 0.0 0.27 9.9 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EGO25149.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Sar8_2 PF03058.14 EGO25150.1 - 0.093 13.3 0.7 0.24 12.0 0.7 1.7 1 0 0 1 1 1 0 Sar8.2 family Retrotrans_gag PF03732.17 EGO25151.1 - 1.6e-06 28.2 2.3 1.6e-06 28.2 2.3 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO25151.1 - 1.6e-05 24.8 1.7 3.4e-05 23.7 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO25151.1 - 4.8e-05 23.2 5.1 8e-05 22.5 5.1 1.4 1 0 0 1 1 1 1 Zinc knuckle M64_N PF16217.5 EGO25151.1 - 0.012 15.2 0.6 0.048 13.2 0.2 2.2 2 1 1 3 3 3 0 Peptidase M64 N-terminus DUF4939 PF16297.5 EGO25151.1 - 0.014 15.3 0.1 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) FAD_binding_3 PF01494.19 EGO25152.1 - 1.7e-67 228.1 0.0 2.2e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGO25152.1 - 0.0037 16.4 0.1 0.0077 15.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO25152.1 - 0.005 17.0 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO25152.1 - 0.022 14.0 0.1 0.13 11.5 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO25152.1 - 0.052 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EGO25152.1 - 0.087 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EGO25152.1 - 0.094 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EGO25152.1 - 0.1 13.2 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Self-incomp_S1 PF05938.11 EGO25153.1 - 0.035 14.6 0.6 0.036 14.6 0.6 1.0 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 DEAD PF00270.29 EGO25154.1 - 2e-20 73.3 0.0 2.6e-18 66.4 0.0 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO25154.1 - 8.4e-13 48.6 0.0 3.3e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO25154.1 - 0.0019 18.2 0.0 0.0048 16.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Yae1_N PF09811.9 EGO25156.1 - 0.008 15.9 1.9 0.033 13.9 0.3 2.0 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Peptidase_M19 PF01244.21 EGO25157.1 - 6.4e-104 347.5 0.0 8.1e-104 347.2 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FAD_binding_2 PF00890.24 EGO25158.1 - 3.3e-88 296.6 0.4 3.9e-88 296.3 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EGO25158.1 - 7.2e-22 77.3 0.0 1.9e-21 76.0 0.0 1.8 2 0 0 2 2 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EGO25158.1 - 2e-12 47.4 1.0 4.2e-11 43.0 1.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO25158.1 - 3.1e-11 43.1 0.2 2.8e-09 36.7 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO25158.1 - 6.7e-10 39.1 1.1 3.7e-09 36.7 0.2 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGO25158.1 - 2.3e-09 37.1 0.5 4e-09 36.3 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO25158.1 - 8.2e-06 25.3 1.7 1.6e-05 24.3 1.7 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGO25158.1 - 3.1e-05 22.9 4.4 0.00015 20.6 0.6 2.8 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 EGO25158.1 - 4.8e-05 22.6 3.4 0.00012 21.3 1.2 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGO25158.1 - 0.00012 21.5 0.2 0.15 11.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO25158.1 - 0.00026 20.3 1.2 0.025 13.8 0.6 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EGO25158.1 - 0.00033 20.0 0.7 0.00063 19.1 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EGO25158.1 - 0.0012 18.2 1.8 0.0034 16.8 0.7 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EGO25158.1 - 0.0034 17.9 0.7 0.069 13.7 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO25158.1 - 0.0058 15.7 0.1 0.039 13.0 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EGO25158.1 - 0.037 14.5 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EGO25158.1 - 0.055 13.5 0.3 0.7 9.9 0.3 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding AAA_18 PF13238.6 EGO25159.1 - 4.7e-07 30.4 0.1 5e-06 27.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EGO25159.1 - 0.00026 20.8 0.1 0.002 17.9 0.1 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EGO25159.1 - 0.0016 18.6 0.0 0.005 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGO25159.1 - 0.0051 16.1 0.1 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 EGO25159.1 - 0.031 13.4 0.0 0.076 12.2 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 EGO25159.1 - 0.034 14.5 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EGO25159.1 - 0.04 14.2 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EGO25159.1 - 0.058 12.8 0.1 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 6PF2K PF01591.18 EGO25159.1 - 0.24 10.7 0.3 0.5 9.6 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Apolipoprotein PF01442.18 EGO25160.1 - 0.0042 17.0 16.8 0.011 15.7 16.8 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EGO25160.1 - 0.021 15.4 23.1 0.17 12.5 5.1 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 EGO25160.1 - 0.12 12.5 12.2 0.09 12.9 2.8 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) LEA_4 PF02987.16 EGO25160.1 - 0.15 12.2 37.2 0.21 11.7 1.0 5.1 3 1 2 5 5 5 0 Late embryogenesis abundant protein ApoO PF09769.9 EGO25160.1 - 0.49 10.3 4.8 6.6 6.7 0.9 2.5 1 1 1 2 2 2 0 Apolipoprotein O YtxH PF12732.7 EGO25160.1 - 0.86 10.2 27.3 1.8e+04 -8.2 27.3 3.5 1 1 0 1 1 1 0 YtxH-like protein DUF2524 PF10732.9 EGO25160.1 - 2.5 8.5 9.2 1.6 9.1 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) DUF3584 PF12128.8 EGO25160.1 - 6 4.2 17.1 6.2 4.2 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NAGLU PF05089.12 EGO25161.1 - 2.3e-131 437.7 7.3 2.3e-131 437.7 7.3 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EGO25161.1 - 1.3e-72 244.6 2.9 1.8e-72 244.1 2.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EGO25161.1 - 8.7e-21 73.5 0.0 2.2e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain APG5 PF04106.12 EGO25162.1 - 3e-62 210.2 0.0 3.9e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Fungal_trans PF04082.18 EGO25163.1 - 2.1e-07 30.2 0.1 3.5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPT PF03151.16 EGO25164.1 - 2.1e-23 83.1 16.8 2.7e-23 82.8 16.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO25164.1 - 4.4e-06 26.9 35.6 0.0028 17.8 12.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGO25164.1 - 0.00045 19.5 17.9 0.00062 19.1 17.9 1.2 1 0 0 1 1 1 1 UAA transporter family Med31 PF05669.12 EGO25165.1 - 3.9e-37 126.1 8.8 4.7e-37 125.9 8.8 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.11 EGO25165.1 - 0.58 10.0 3.3 9.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat Peptidase_C12 PF01088.21 EGO25166.1 - 2.7e-54 184.1 0.0 4.2e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGO25166.1 - 1.7e-14 53.4 0.2 3.6e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Aldo_ket_red PF00248.21 EGO25167.1 - 4.5e-46 157.4 0.1 9.6e-44 149.7 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 EGO25168.1 - 1e-80 271.9 24.6 1.2e-80 271.6 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO25168.1 - 7.6e-19 67.8 44.4 4.4e-12 45.6 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGO25168.1 - 0.0018 16.6 2.2 0.0018 16.6 2.2 3.9 4 1 1 5 5 5 1 Organic Anion Transporter Polypeptide (OATP) family Rick_17kDa_Anti PF05433.15 EGO25168.1 - 7.8 6.5 10.4 1.6 8.7 5.8 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain NTP_transferase PF00483.23 EGO25170.1 - 6.8e-42 143.8 0.0 1.7e-41 142.4 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGO25170.1 - 5.2e-07 30.2 0.2 1.4e-06 28.7 0.2 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 EGO25170.1 - 0.00027 20.8 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.19 EGO25170.1 - 0.021 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CK2S PF15011.6 EGO25170.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate DivIC PF04977.15 EGO25170.1 - 0.11 12.2 2.3 0.098 12.4 0.7 1.6 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 EGO25170.1 - 0.16 12.4 0.7 0.31 11.5 0.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB FAD_binding_3 PF01494.19 EGO25171.1 - 2.7e-72 243.9 0.0 3.4e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGO25171.1 - 1.6e-05 24.2 0.4 4e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO25171.1 - 0.0001 21.7 0.1 0.00022 20.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO25171.1 - 0.00036 19.4 0.1 0.00083 18.2 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO25171.1 - 0.0004 20.6 0.2 0.0016 18.6 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGO25171.1 - 0.0011 18.4 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO25171.1 - 0.0017 17.7 0.4 0.003 16.9 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO25171.1 - 0.0021 17.0 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 EGO25171.1 - 0.0027 17.0 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGO25171.1 - 0.019 14.1 0.2 0.03 13.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 EGO25171.1 - 0.024 14.2 3.1 0.25 10.9 0.6 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO25172.1 - 5.1e-72 243.0 0.0 6.4e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGO25172.1 - 0.00019 20.4 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EGO25172.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO25172.1 - 0.00074 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO25172.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO25172.1 - 0.021 13.6 0.0 0.04 12.6 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EGO25172.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EGO25172.1 - 0.026 13.9 0.2 0.051 12.9 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO25172.1 - 0.031 14.8 0.0 0.094 13.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO25172.1 - 0.041 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO25172.1 - 0.072 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGO25172.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Rhodanese PF00581.20 EGO25173.1 - 6.3e-18 65.3 0.0 1.3e-10 41.7 0.0 2.6 2 1 0 2 2 2 2 Rhodanese-like domain AA_permease PF00324.21 EGO25175.1 - 8.3e-113 377.5 41.6 9.3e-113 377.3 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO25175.1 - 2.2e-30 105.8 50.4 2.8e-30 105.5 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.19 EGO25176.1 - 7.8e-66 222.7 0.0 9.9e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO25176.1 - 0.0091 15.3 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGO25176.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EGO25176.1 - 0.047 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 EGO25176.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RhoGAP PF00620.27 EGO25178.1 - 9e-31 106.8 0.0 2e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 EGO25178.1 - 2.6e-30 105.1 0.0 7.5e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain FlgM PF04316.13 EGO25178.1 - 0.16 12.3 0.0 20 5.6 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Pheromone PF08015.11 EGO25179.1 - 1.8 9.7 6.8 3.4 8.8 6.8 1.4 1 1 0 1 1 1 0 Fungal mating-type pheromone NAD_binding_2 PF03446.15 EGO25180.1 - 6.7e-09 36.1 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGO25180.1 - 7.7e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EGO25180.1 - 0.00022 20.8 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 EGO25180.1 - 0.0012 18.7 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 EGO25180.1 - 0.0028 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGO25180.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGO25180.1 - 0.039 13.8 0.2 0.06 13.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nitro_FeMo-Co PF02579.17 EGO25180.1 - 0.092 13.1 0.1 0.39 11.1 0.1 2.0 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Hydrolase_6 PF13344.6 EGO25182.1 - 6.6e-24 83.9 0.0 1.1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO25182.1 - 4.3e-23 81.2 0.0 1.5e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGO25182.1 - 0.00043 20.6 0.0 1.6 9.0 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO25182.1 - 0.11 12.6 0.0 0.92 9.6 0.0 2.4 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 EGO25183.1 - 1.3e-12 47.3 1.1 2.1e-12 46.6 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO25183.1 - 7.2e-09 35.6 8.5 2e-08 34.2 8.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EGO25183.1 - 5.9e-08 32.8 11.5 0.00046 20.5 2.9 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO25183.1 - 2.5e-06 27.6 1.9 2.5e-06 27.6 1.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO25183.1 - 0.00014 22.4 13.3 0.0035 18.0 1.9 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO25183.1 - 0.0002 21.2 4.0 0.029 14.4 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO25183.1 - 1.2 9.0 5.8 5.1 6.9 0.7 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 EGO25183.1 - 4.5 7.6 9.3 0.49 10.7 2.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 EGO25183.1 - 9.6 6.1 8.3 0.43 10.4 1.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain adh_short_C2 PF13561.6 EGO25184.1 - 0.00024 20.7 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Astro_capsid_p PF12226.8 EGO25186.1 - 0.23 10.6 1.9 0.45 9.6 0.8 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein F-box-like PF12937.7 EGO25186.1 - 0.31 10.9 4.3 0.12 12.3 1.2 2.0 2 0 0 2 2 2 0 F-box-like ECH_1 PF00378.20 EGO25187.1 - 9.5e-84 280.6 0.1 1.1e-83 280.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO25187.1 - 6.1e-38 131.1 0.5 2.4e-33 116.1 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGO25187.1 - 0.043 13.8 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Ank PF00023.30 EGO25188.1 - 0.012 16.0 0.0 2.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat YCII PF03795.14 EGO25189.1 - 1.4e-07 31.8 0.0 1.7e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Asparaginase_2 PF01112.18 EGO25190.1 - 1.6e-70 237.6 0.0 2.6e-52 177.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Pex24p PF06398.11 EGO25191.1 - 8.4e-26 90.8 9.3 8e-25 87.6 1.8 2.8 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Mannosyl_trans2 PF04188.13 EGO25192.1 - 7.2e-53 180.5 27.7 9.3e-53 180.1 27.7 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF3712 PF12505.8 EGO25193.1 - 7.3e-104 342.9 63.8 6.2e-27 94.3 0.3 10.1 9 1 1 10 10 10 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EGO25193.1 - 4.6e-09 36.7 24.6 0.037 14.6 0.2 9.3 10 0 0 10 10 10 5 Late embryogenesis abundant protein p450 PF00067.22 EGO25197.1 - 9e-78 262.1 0.0 1e-77 261.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO25198.1 - 5.1e-73 246.4 0.0 6.3e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO25199.1 - 2.7e-65 220.9 0.0 1.2e-55 189.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 TPR_2 PF07719.17 EGO25201.1 - 1e-17 62.7 18.3 0.019 15.0 0.9 11.8 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGO25201.1 - 6.7e-17 61.8 16.9 0.00025 21.5 0.2 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25201.1 - 4.7e-16 57.6 9.0 0.2 12.0 0.0 11.4 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGO25201.1 - 2.4e-15 55.9 1.9 0.0052 16.4 0.0 7.2 7 0 0 7 7 7 2 TPR repeat TPR_14 PF13428.6 EGO25201.1 - 2.5e-14 52.7 14.1 0.0036 18.0 0.1 10.1 8 2 2 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO25201.1 - 3.4e-12 45.6 12.3 0.055 13.3 0.0 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25201.1 - 4.3e-11 43.3 11.4 0.011 16.4 0.0 7.7 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25201.1 - 2.2e-09 37.5 25.0 0.00012 22.3 1.2 9.1 9 2 1 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO25201.1 - 4.2e-09 35.8 10.6 0.11 12.5 0.0 7.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGO25201.1 - 2.1e-08 34.3 7.4 0.00038 20.9 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25201.1 - 6.1e-08 32.5 8.1 0.47 11.0 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGO25201.1 - 0.00013 22.2 4.3 0.02 15.2 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGO25201.1 - 0.00033 21.1 0.4 0.33 11.4 0.0 3.6 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation ANAPC3 PF12895.7 EGO25201.1 - 0.005 17.0 10.4 20 5.5 0.1 6.5 7 0 0 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGO25201.1 - 0.028 14.6 17.9 0.031 14.4 0.3 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EGO25201.1 - 0.035 14.2 1.1 14 5.8 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 SNAP PF14938.6 EGO25201.1 - 0.045 13.2 5.3 0.12 11.8 0.1 3.2 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 EGO25201.1 - 0.058 12.8 0.0 0.058 12.8 0.0 4.2 5 0 0 5 5 5 0 MalT-like TPR region ADP_ribosyl_GH PF03747.14 EGO25201.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase NARP1 PF12569.8 EGO25201.1 - 0.092 11.6 7.2 5.3 5.8 0.2 4.0 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 Chitin_synth_2 PF03142.15 EGO25202.1 - 1e-231 770.1 1.5 1.3e-210 700.6 0.6 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGO25202.1 - 5.2e-14 52.7 0.0 1.1e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGO25202.1 - 4.8e-13 49.5 5.6 4.8e-13 49.5 5.6 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGO25202.1 - 0.017 14.6 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGO25202.1 - 0.22 11.3 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.20 EGO25203.1 - 7.5e-06 25.8 0.8 1.9e-05 24.5 0.1 1.9 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO25203.1 - 0.0022 17.6 0.6 0.012 15.2 0.6 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGO25203.1 - 0.0022 17.7 0.8 0.0047 16.6 0.3 1.7 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EGO25203.1 - 0.022 14.7 0.1 0.04 13.9 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Dus PF01207.17 EGO25204.1 - 7.4e-71 238.8 0.0 9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 EGO25204.1 - 2.3e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 EGO25204.1 - 0.00012 21.9 0.1 0.0024 17.7 0.0 2.2 1 1 1 2 2 2 1 SOR/SNZ family NMO PF03060.15 EGO25204.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EGO25204.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 EGO25204.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain BLM10_mid PF16507.5 EGO25205.1 - 2.5e-193 643.5 0.1 2.5e-193 643.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region Con-6 PF10346.9 EGO25205.1 - 2e-45 152.5 6.0 2.9e-14 52.8 0.4 3.6 3 0 0 3 3 3 3 Conidiation protein 6 DUF3437 PF11919.8 EGO25205.1 - 6.9e-29 99.6 0.1 5.1e-28 96.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EGO25205.1 - 1.7e-09 37.1 6.5 0.21 11.9 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EGO25205.1 - 4.7e-06 26.9 5.6 0.077 13.4 0.0 6.6 8 1 0 8 8 8 2 HEAT repeats SpoIIIAH PF12685.7 EGO25205.1 - 0.0042 16.9 0.4 0.43 10.4 0.0 2.7 3 0 0 3 3 3 1 SpoIIIAH-like protein BLM10_N PF16547.5 EGO25205.1 - 0.012 15.9 0.1 0.033 14.5 0.1 1.8 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal DUF4119 PF13494.6 EGO25205.1 - 0.013 15.6 0.1 0.17 12.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) Svf1_C PF17187.4 EGO25205.1 - 0.025 14.4 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain Cnd1 PF12717.7 EGO25205.1 - 0.037 14.1 0.1 0.89 9.6 0.0 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Dynamitin PF04912.14 EGO25206.1 - 1.6e-41 143.0 1.5 1.7e-41 142.8 1.5 1.0 1 0 0 1 1 1 1 Dynamitin SlyX PF04102.12 EGO25206.1 - 0.0055 17.3 2.7 3 8.5 0.2 2.7 3 0 0 3 3 3 2 SlyX TPR_MLP1_2 PF07926.12 EGO25206.1 - 0.1 12.6 1.7 0.16 12.0 0.5 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.11 EGO25206.1 - 0.35 10.9 2.3 4.6 7.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_M22 PF00814.25 EGO25207.1 - 6.9e-69 232.6 0.0 9.2e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family HbrB PF08539.11 EGO25208.1 - 1.7e-59 200.6 0.0 4.9e-59 199.1 0.0 1.8 1 0 0 1 1 1 1 HbrB-like PsbI PF02532.14 EGO25208.1 - 0.15 12.0 0.2 0.32 11.0 0.2 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) ATPase-cat_bd PF12156.8 EGO25209.1 - 0.17 12.7 0.0 0.2 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase ATP-sulfurylase PF01747.17 EGO25212.1 - 2.2e-87 292.0 0.1 3.1e-87 291.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EGO25212.1 - 2.9e-51 173.3 0.0 4.9e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 EGO25212.1 - 1.2e-48 165.0 0.0 1.8e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 EGO25212.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Amidohydro_3 PF07969.11 EGO25215.1 - 2e-05 24.3 0.7 0.0061 16.1 0.3 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO25215.1 - 0.00052 19.4 0.0 0.073 12.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Sec_GG PF07549.14 EGO25216.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Amidohydro_3 PF07969.11 EGO25219.1 - 1.9e-06 27.6 0.9 0.00098 18.7 0.4 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO25219.1 - 7.9e-05 22.1 0.0 0.076 12.3 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family ERO1 PF04137.15 EGO25220.1 - 1.9e-14 53.7 0.0 1.9e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Aldo_ket_red PF00248.21 EGO25221.1 - 5.1e-40 137.5 0.1 5.1e-38 130.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-CHCC PF10276.9 EGO25222.1 - 5.4e-17 61.5 3.1 7.8e-17 61.0 3.1 1.2 1 0 0 1 1 1 1 Zinc-finger domain EHN PF06441.12 EGO25223.1 - 5.3e-34 116.8 0.2 3.6e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EGO25223.1 - 7.3e-09 35.6 0.1 1.1e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO25223.1 - 0.00036 21.2 2.7 0.0017 19.0 2.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 EGO25224.1 - 3e-50 171.3 0.0 3.4e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3921 PF13060.6 EGO25224.1 - 0.058 13.4 0.1 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3921) Abhydrolase_1 PF00561.20 EGO25225.1 - 1.1e-13 51.5 0.0 1.6e-12 47.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO25225.1 - 4.9e-12 46.9 0.1 7.1e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO25225.1 - 0.007 15.7 0.0 0.024 13.9 0.0 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 EGO25225.1 - 0.0091 16.4 0.1 0.024 15.0 0.0 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus MmgE_PrpD PF03972.14 EGO25226.1 - 1.3e-152 508.4 0.0 1.5e-152 508.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RNase_H2-Ydr279 PF09468.10 EGO25228.1 - 1.2e-22 80.8 0.0 1.2e-22 80.8 0.0 1.6 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EGO25228.1 - 2.3e-15 56.6 0.0 8.9e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain Slu7 PF11708.8 EGO25229.1 - 8.3e-106 353.6 14.9 8.3e-106 353.6 14.9 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGO25229.1 - 0.05 13.4 0.3 0.095 12.5 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle SNF2_N PF00176.23 EGO25230.1 - 1.1e-61 208.5 0.3 2.4e-61 207.4 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EGO25230.1 - 2.2e-24 85.7 0.2 1e-23 83.6 0.2 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EGO25230.1 - 6.2e-20 70.9 5.3 1.1e-14 54.1 0.4 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EGO25230.1 - 5.6e-19 68.5 0.0 1.5e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 EGO25230.1 - 8.5e-09 35.8 0.9 8.5e-09 35.8 0.9 4.1 3 1 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 EGO25230.1 - 1.2e-08 35.1 0.2 7e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO25230.1 - 4.1e-07 29.5 0.4 1.4e-06 27.7 0.4 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CDH1_2_SANT_HL1 PF18375.1 EGO25230.1 - 0.00036 21.1 1.6 0.0014 19.3 0.2 2.7 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 ERCC3_RAD25_C PF16203.5 EGO25230.1 - 0.00057 19.2 0.2 0.0014 17.8 0.2 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 EGO25230.1 - 0.02 15.1 0.5 0.06 13.5 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain FlhC PF05280.11 EGO25230.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Asparaginase_2 PF01112.18 EGO25231.1 - 1.8e-57 194.7 2.1 2.6e-57 194.2 2.1 1.2 1 0 0 1 1 1 1 Asparaginase NAD_binding_4 PF07993.12 EGO25232.1 - 1.2e-35 123.0 0.0 1.8e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO25232.1 - 6.5e-23 81.0 0.4 1.2e-17 63.7 0.1 2.5 2 1 1 3 3 3 2 AMP-binding enzyme PP-binding PF00550.25 EGO25232.1 - 6.4e-11 42.4 0.0 1.5e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGO25232.1 - 1.8e-09 37.4 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family WD40_alt PF14077.6 EGO25233.1 - 0.15 11.9 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif IF-2B PF01008.17 EGO25234.1 - 1.1e-54 185.6 0.0 1.3e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.13 EGO25235.1 - 1.3e-30 106.8 0.0 6.6e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO25235.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_1 PF00515.28 EGO25237.1 - 1e-16 59.9 5.6 0.0029 17.4 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25237.1 - 3.4e-14 52.1 11.2 0.0009 19.5 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25237.1 - 5.4e-14 51.1 11.2 0.0078 16.3 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25237.1 - 1.5e-11 43.5 2.1 0.2 12.0 0.3 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO25237.1 - 3.7e-11 42.9 12.3 0.0047 17.6 0.2 5.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO25237.1 - 3.8e-11 42.5 5.7 0.00065 19.3 1.8 4.4 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.6 EGO25237.1 - 2.4e-09 37.5 13.1 4e-06 27.3 0.9 4.0 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25237.1 - 1.2e-08 35.1 13.9 0.0081 16.4 3.2 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25237.1 - 7e-07 29.8 9.8 0.0024 18.5 2.1 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGO25237.1 - 2.2e-05 24.7 6.1 0.13 12.6 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO25237.1 - 6.6e-05 23.1 3.4 0.0037 17.5 1.5 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGO25237.1 - 0.00019 21.5 6.2 0.16 12.1 1.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat DUF3507 PF12015.8 EGO25237.1 - 0.084 12.6 0.0 2.8 7.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3507) TPR_7 PF13176.6 EGO25237.1 - 0.19 11.8 9.9 1 9.5 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO25237.1 - 1.4 9.7 4.2 58 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGO25237.1 - 1.4 9.0 5.0 1.6 8.9 0.5 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF382 PF04037.13 EGO25238.1 - 0.076 13.2 1.5 0.091 12.9 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF382) ANAPC_CDC26 PF10471.9 EGO25238.1 - 0.26 12.2 9.5 3.1 8.7 9.5 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 PRA1 PF03208.19 EGO25239.1 - 3.3e-34 117.5 0.3 3.8e-34 117.4 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein YwiC PF14256.6 EGO25239.1 - 0.072 13.4 0.5 0.072 13.4 0.5 2.0 2 0 0 2 2 2 0 YwiC-like protein MPS-4 PF17523.2 EGO25239.1 - 0.13 12.4 0.5 0.28 11.4 0.3 1.7 1 1 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF2718 PF10918.8 EGO25239.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) PSI_PsaJ PF01701.18 EGO25239.1 - 1.3 9.6 7.6 0.29 11.7 1.1 2.7 2 1 1 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ DUF1270 PF06900.11 EGO25239.1 - 1.9 8.9 5.7 0.32 11.4 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Zn_clus PF00172.18 EGO25240.1 - 6.7e-05 22.9 11.9 0.00011 22.2 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EGO25240.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PrmC_N PF17827.1 EGO25241.1 - 1.3e-05 25.6 0.1 2.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 EGO25241.1 - 5.8e-05 23.7 0.0 0.00032 21.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO25241.1 - 9.9e-05 22.2 0.0 0.00031 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGO25241.1 - 0.0028 17.1 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EGO25241.1 - 0.004 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO25241.1 - 0.031 13.8 0.0 0.23 11.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Glycos_transf_N PF04413.16 EGO25241.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Allantoicase PF03561.15 EGO25242.1 - 3.2e-91 302.8 0.0 5.4e-45 152.9 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 EGO25242.1 - 9.4e-49 165.7 0.0 1.4e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase BRE1 PF08647.11 EGO25243.1 - 5.6e-23 80.8 6.9 5.6e-23 80.8 6.9 9.7 9 2 0 9 9 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EGO25243.1 - 2.1e-08 33.9 9.0 4e-08 33.0 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO25243.1 - 4.8e-07 29.5 10.9 1e-06 28.5 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO25243.1 - 1.5e-06 28.0 12.0 3e-06 27.0 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO25243.1 - 2.9e-06 27.1 12.4 6.7e-06 26.0 12.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGO25243.1 - 5.1e-05 23.5 10.7 0.0001 22.5 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO25243.1 - 9.5e-05 22.3 9.8 0.00019 21.3 9.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO25243.1 - 0.00028 20.7 7.9 0.00055 19.7 7.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HMMR_N PF15905.5 EGO25243.1 - 0.00092 18.8 11.9 0.00092 18.8 11.9 4.7 3 2 1 5 5 5 2 Hyaluronan mediated motility receptor N-terminal zf-rbx1 PF12678.7 EGO25243.1 - 0.0021 18.3 5.7 0.0021 18.3 5.7 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain Spc7 PF08317.11 EGO25243.1 - 0.0024 16.8 6.9 0.0024 16.8 6.9 5.5 4 2 1 6 6 6 1 Spc7 kinetochore protein GIT_CC PF16559.5 EGO25243.1 - 0.012 15.5 0.1 0.012 15.5 0.1 6.7 8 0 0 8 8 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-RING_6 PF14835.6 EGO25243.1 - 0.016 15.1 3.5 0.035 14.0 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Nbs1_C PF08599.10 EGO25243.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.4 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 HR1 PF02185.16 EGO25243.1 - 0.028 14.5 0.0 0.028 14.5 0.0 5.9 4 1 1 5 5 3 0 Hr1 repeat DUF1192 PF06698.11 EGO25243.1 - 0.036 14.1 0.9 0.036 14.1 0.9 8.2 8 1 1 9 9 8 0 Protein of unknown function (DUF1192) GRAM PF02893.20 EGO25243.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 GRAM domain DMPK_coil PF08826.10 EGO25243.1 - 0.13 12.3 0.1 0.13 12.3 0.1 9.4 10 1 0 10 10 10 0 DMPK coiled coil domain like zf-C3HC4_4 PF15227.6 EGO25243.1 - 0.2 11.9 7.5 0.4 10.9 7.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NPV_P10 PF05531.12 EGO25243.1 - 0.25 11.8 0.1 0.25 11.8 0.1 5.8 7 2 0 7 7 5 0 Nucleopolyhedrovirus P10 protein Shugoshin_N PF07558.11 EGO25243.1 - 0.28 11.1 16.3 2 8.3 0.8 5.8 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region DUF1272 PF06906.11 EGO25243.1 - 0.34 11.0 6.0 0.79 9.9 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 EGO25243.1 - 0.55 10.2 4.8 1.3 9.0 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.6 EGO25243.1 - 1.1 9.4 6.2 8.4 6.5 1.6 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Nse PF11789.8 EGO25243.1 - 1.6 8.7 6.7 3.3 7.6 6.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF720 PF05302.11 EGO25243.1 - 4.5 7.1 6.8 3.9 7.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF720) DUF812 PF05667.11 EGO25243.1 - 4.9 5.9 68.0 0.4 9.5 10.3 4.4 1 1 2 3 3 2 0 Protein of unknown function (DUF812) zf-RING_4 PF14570.6 EGO25243.1 - 7 6.5 10.3 11 5.9 8.5 2.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Ribosomal_S9 PF00380.19 EGO25244.1 - 1.2e-45 154.9 0.0 1.8e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CASP_C PF08172.12 EGO25245.1 - 4.5e-27 95.0 1.8 4.5e-27 95.0 1.8 3.8 1 1 2 4 4 4 1 CASP C terminal DUF3110 PF11360.8 EGO25245.1 - 0.023 14.9 0.2 0.055 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) DivIC PF04977.15 EGO25245.1 - 0.066 13.0 27.5 0.066 13.0 0.5 5.3 3 1 2 5 5 5 0 Septum formation initiator ACR_tran PF00873.19 EGO25245.1 - 0.19 9.3 0.5 0.27 8.8 0.5 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FlaC_arch PF05377.11 EGO25245.1 - 0.34 11.3 23.0 0.59 10.6 2.0 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Seadorna_VP6 PF07407.11 EGO25245.1 - 0.7 8.8 4.4 0.13 11.2 1.2 1.4 2 0 0 2 2 2 0 Seadornavirus VP6 protein DUF1192 PF06698.11 EGO25245.1 - 0.74 9.9 10.3 1.7 8.8 0.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.15 EGO25245.1 - 1 9.5 30.7 1.1 9.4 0.3 5.6 5 1 0 5 5 5 0 Basic region leucine zipper DUF1664 PF07889.12 EGO25245.1 - 1.9 8.5 22.1 0.46 10.5 3.6 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) CREPT PF16566.5 EGO25245.1 - 2 8.6 21.4 0.52 10.5 1.6 4.0 3 1 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF641 PF04859.12 EGO25245.1 - 2 8.7 26.8 1.2 9.5 5.4 4.0 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) DUF2203 PF09969.9 EGO25245.1 - 2.1 9.1 18.1 73 4.1 8.3 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) PKcGMP_CC PF16808.5 EGO25245.1 - 2.6 8.0 16.3 1.3 9.0 0.7 4.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GldM_N PF12081.8 EGO25245.1 - 5 7.2 13.9 8.4 6.4 5.5 2.8 1 1 2 3 3 3 0 GldM N-terminal domain DUF2935 PF11155.8 EGO25245.1 - 5.8 7.3 7.9 15 6.0 1.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) YabA PF06156.13 EGO25245.1 - 6.2 7.5 19.4 4.2 8.1 2.5 4.5 3 1 1 4 4 4 0 Initiation control protein YabA Sec34 PF04136.15 EGO25245.1 - 7.2 6.5 21.2 2.2 8.1 0.3 3.4 2 1 1 3 3 3 0 Sec34-like family CASP_C PF08172.12 EGO25246.1 - 5.9e-09 35.6 0.1 9.1e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 CASP C terminal gag-asp_proteas PF13975.6 EGO25248.1 - 0.004 17.7 0.0 0.0055 17.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO25248.1 - 0.0056 17.3 0.0 0.0072 17.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO25248.1 - 0.013 15.3 0.0 0.35 10.6 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease MOZ_SAS PF01853.18 EGO25249.1 - 8.8e-81 269.8 0.3 1.4e-80 269.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGO25249.1 - 1.2e-21 76.1 1.1 2.7e-21 74.9 1.1 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain HTH_Mga PF08280.11 EGO25249.1 - 0.00057 19.9 0.9 0.0014 18.6 0.9 1.6 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_7 PF13508.7 EGO25249.1 - 0.00075 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO25249.1 - 0.0046 17.2 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_11 PF08279.12 EGO25249.1 - 0.073 13.0 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 HTH domain CCDC74_C PF14917.6 EGO25256.1 - 0.0017 18.8 2.5 0.0035 17.9 2.5 1.5 1 0 0 1 1 1 1 Coiled coil protein 74, C terminal TMF_DNA_bd PF12329.8 EGO25256.1 - 0.0049 16.8 11.4 0.052 13.6 1.9 2.5 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 EGO25256.1 - 0.026 14.7 9.8 0.2 11.9 4.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF98 PF01947.16 EGO25256.1 - 0.034 14.1 0.7 0.055 13.4 0.7 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase Spc7 PF08317.11 EGO25256.1 - 0.13 11.2 8.2 0.16 10.8 8.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 EGO25256.1 - 0.19 12.2 7.7 0.32 11.5 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 FAM76 PF16046.5 EGO25256.1 - 0.2 11.0 7.3 0.25 10.7 7.3 1.1 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 EGO25256.1 - 0.26 10.3 9.1 0.33 10.0 9.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PIEZO PF15917.5 EGO25256.1 - 0.54 9.7 5.7 0.78 9.2 5.7 1.3 1 0 0 1 1 1 0 Piezo PAC4 PF16093.5 EGO25257.1 - 4.7e-24 84.4 0.1 6.5e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Pkinase PF00069.25 EGO25259.1 - 5.4e-52 176.8 0.1 9.3e-52 176.0 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25259.1 - 5.2e-22 78.4 0.0 7.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO25259.1 - 2.6e-05 24.3 0.1 4.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO25259.1 - 0.00035 20.2 0.3 0.00084 19.0 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EGO25259.1 - 0.013 15.1 0.1 0.033 13.8 0.1 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.12 EGO25261.1 - 1.1e-50 172.3 0.0 4.6e-47 160.4 0.0 2.0 1 1 1 2 2 2 2 Putative Phosphatase HAD PF12710.7 EGO25261.1 - 0.00058 20.3 0.1 0.002 18.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EGO25261.1 - 0.15 11.6 0.0 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) HAD_2 PF13419.6 EGO25261.1 - 0.29 11.2 0.9 51 3.9 1.1 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PH_TFIIH PF08567.11 EGO25262.1 - 2.3e-19 69.5 0.0 4.6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 EGO25262.1 - 1.3e-18 66.7 0.1 4.9e-13 48.9 0.1 2.7 2 0 0 2 2 2 2 BSD domain GvpG PF05120.12 EGO25262.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Retrotrans_gag PF03732.17 EGO25267.1 - 3e-07 30.6 1.6 3e-07 30.6 1.6 2.2 2 1 0 2 2 2 1 Retrotransposon gag protein M64_N PF16217.5 EGO25267.1 - 0.025 14.2 0.4 0.092 12.3 0.1 2.1 1 1 1 2 2 2 0 Peptidase M64 N-terminus DUF4939 PF16297.5 EGO25267.1 - 0.038 13.9 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Sbi-IV PF11621.8 EGO25267.1 - 0.062 13.7 0.7 0.19 12.1 0.7 1.9 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI BrnA_antitoxin PF14384.6 EGO25267.1 - 0.095 13.2 0.4 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system V-ATPase_G PF03179.15 EGO25267.1 - 8.2 7.0 9.6 0.8 10.3 2.2 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit MLVIN_C PF18697.1 EGO25268.1 - 0.0097 16.0 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Pkinase PF00069.25 EGO25271.1 - 3.6e-53 180.6 0.0 1.6e-52 178.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25271.1 - 1.1e-34 120.0 0.1 5.6e-33 114.3 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGO25271.1 - 0.00091 19.2 0.1 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO25271.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO25271.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGO25271.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGO25271.1 - 0.21 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Helitron_like_N PF14214.6 EGO25272.1 - 5e-22 79.0 0.0 1.1e-21 77.9 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Retrotrans_gag PF03732.17 EGO25276.1 - 9.8e-07 29.0 0.1 9.8e-07 29.0 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein ADH_zinc_N PF00107.26 EGO25277.1 - 6e-30 103.9 0.3 8.2e-30 103.5 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO25277.1 - 3.4e-13 50.8 0.0 5.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO25277.1 - 1.4e-06 28.1 0.0 1.1e-05 25.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGO25277.1 - 0.064 12.7 0.5 0.095 12.1 0.5 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RNA_pol_A_bac PF01000.26 EGO25278.1 - 5e-30 104.1 0.0 8.7e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGO25278.1 - 1.5e-16 59.5 0.0 2.2e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RabGAP-TBC PF00566.18 EGO25279.1 - 4.9e-53 180.0 0.2 4.9e-53 180.0 0.2 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.6 EGO25279.1 - 0.0055 16.8 8.1 0.0055 16.8 8.1 1.8 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Phage_int_SAM_1 PF02899.17 EGO25279.1 - 0.0097 16.2 1.7 0.85 10.0 0.8 2.9 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain CENP-F_leu_zip PF10473.9 EGO25279.1 - 0.021 14.8 3.8 0.041 13.9 3.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 EGO25279.1 - 0.059 13.5 1.7 0.11 12.6 1.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EGO25279.1 - 0.086 13.3 3.8 0.2 12.1 3.8 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIVA PF05103.13 EGO25279.1 - 0.14 12.3 2.9 0.31 11.1 2.3 1.9 2 0 0 2 2 2 0 DivIVA protein Cnn_1N PF07989.11 EGO25279.1 - 0.43 10.8 10.6 0.19 11.9 5.5 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 EGO25279.1 - 4.2 7.9 11.2 0.14 12.6 4.3 2.1 3 0 0 3 3 3 0 Apg6 coiled-coil region DivIC PF04977.15 EGO25279.1 - 8.7 6.2 7.4 14 5.5 0.4 2.7 2 1 1 3 3 3 0 Septum formation initiator Amidohydro_1 PF01979.20 EGO25280.1 - 3.7e-36 125.2 0.0 4.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO25280.1 - 9e-17 61.7 0.2 3.3e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Aminotran_3 PF00202.21 EGO25281.1 - 3.9e-115 384.8 0.0 4.7e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGO25281.1 - 4.1e-05 22.9 0.0 6.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.6 EGO25282.1 - 6.3e-12 45.6 4.9 1.1e-11 44.8 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGO25282.1 - 1.7e-07 30.9 1.8 1.7e-07 30.9 1.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGO25282.1 - 2.1e-06 27.4 4.7 3.7e-06 26.7 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGO25282.1 - 5.1e-06 26.4 1.4 9.5e-06 25.6 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGO25282.1 - 2.1e-05 24.4 1.8 3.8e-05 23.5 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGO25282.1 - 4.2e-05 23.7 5.1 0.00015 22.0 5.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO25282.1 - 0.00026 20.8 6.1 0.0023 17.7 6.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO25282.1 - 0.0003 20.6 2.8 0.00057 19.7 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGO25282.1 - 0.00031 20.5 3.2 0.00054 19.7 3.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGO25282.1 - 0.0006 19.6 1.4 0.0011 18.8 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO25282.1 - 0.0012 18.8 3.5 0.064 13.3 1.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 EGO25282.1 - 0.0087 16.2 1.6 0.023 14.9 1.6 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EGO25282.1 - 0.014 15.5 2.4 0.027 14.6 2.4 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EGO25282.1 - 0.14 12.1 4.2 1.5 8.8 1.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UBZ_FAAP20 PF15750.5 EGO25282.1 - 0.22 11.5 0.9 7.2 6.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C2H2_9 PF16293.5 EGO25282.1 - 0.31 10.9 2.4 14 5.7 0.1 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_17 PF17120.5 EGO25282.1 - 0.34 10.6 1.6 0.74 9.5 1.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HSP9_HSP12 PF04119.12 EGO25283.1 - 2.3e-23 82.3 9.3 2.3e-23 82.3 9.3 2.1 2 1 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.6 EGO25283.1 - 0.013 15.8 6.8 15 6.0 6.9 3.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein Josephin PF02099.17 EGO25284.1 - 1e-26 94.0 5.5 5.1e-18 65.7 0.1 3.8 2 1 2 4 4 4 3 Josephin ATG27 PF09451.10 EGO25285.1 - 1.5e-65 221.7 0.0 1.8e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGO25285.1 - 0.00029 20.0 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Phage_holin_3_6 PF07332.11 EGO25285.1 - 0.17 12.0 0.4 4.6 7.3 0.0 2.5 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 EGO25285.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GPI-anchored PF10342.9 EGO25288.1 - 2.7e-08 34.5 0.3 3.5e-08 34.1 0.3 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EGO25288.1 - 0.0028 17.4 0.3 0.0039 17.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Big_3_5 PF16640.5 EGO25288.1 - 0.013 15.7 0.6 0.017 15.3 0.6 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) SMODS PF18144.1 EGO25288.1 - 0.16 12.2 0.4 0.22 11.7 0.4 1.2 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DEAD PF00270.29 EGO25289.1 - 7.7e-39 133.3 0.0 6.1e-38 130.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO25289.1 - 9.2e-23 80.7 0.2 3.5e-22 78.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGO25289.1 - 2.9e-20 72.3 2.5 1.2e-19 70.3 2.5 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain TGT PF01702.18 EGO25290.1 - 3.7e-123 411.1 0.0 4.4e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF3511 PF12023.8 EGO25290.1 - 0.16 11.8 0.0 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) tRNA-synt_1b PF00579.25 EGO25291.1 - 7e-10 38.7 0.3 1.1e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EMP70 PF02990.16 EGO25292.1 - 9.8e-199 661.3 0.1 9.8e-199 661.3 0.1 1.5 2 0 0 2 2 2 1 Endomembrane protein 70 Mig-14 PF07395.11 EGO25293.1 - 0.00051 19.5 0.0 0.00076 18.9 0.0 1.1 1 0 0 1 1 1 1 Mig-14 Abhydrolase_1 PF00561.20 EGO25294.1 - 5.1e-17 62.4 0.2 1.3e-15 57.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO25294.1 - 0.00051 20.7 0.0 0.00068 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO25294.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO25295.1 - 2.7e-08 33.8 0.0 3.3e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO25295.1 - 0.00081 20.0 0.0 0.00098 19.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CTP_transf_1 PF01148.20 EGO25296.1 - 3.4e-73 246.7 20.0 5.2e-73 246.1 20.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family COX7C PF02935.16 EGO25296.1 - 0.081 13.2 0.1 0.081 13.2 0.1 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc Topoisom_I PF01028.20 EGO25297.1 - 9.7e-100 332.6 7.7 9.7e-100 332.6 7.7 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGO25297.1 - 4.1e-95 317.3 4.3 4.1e-95 317.3 4.3 3.0 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGO25297.1 - 8.1e-40 134.6 0.8 2.3e-39 133.1 0.8 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain PIN_5 PF08745.11 EGO25297.1 - 0.24 10.8 3.4 1 8.8 0.4 2.6 2 0 0 2 2 2 0 PINc domain ribonuclease TetR_C_23 PF17931.1 EGO25297.1 - 0.36 10.9 0.0 0.36 10.9 0.0 3.6 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain NDUF_B12 PF08122.12 EGO25298.1 - 5.2e-21 74.5 0.6 5.6e-21 74.3 0.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family HAD_2 PF13419.6 EGO25300.1 - 1.5e-07 31.6 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO25300.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like PALP PF00291.25 EGO25301.1 - 1.4e-78 264.3 0.1 2e-78 263.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGO25301.1 - 3.9e-42 141.9 0.0 6e-24 83.6 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HU-HIG PF18291.1 EGO25301.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Vps8 PF12816.7 EGO25304.1 - 2e-68 229.8 0.3 2.5e-65 219.7 0.0 2.6 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGO25304.1 - 0.046 13.6 0.0 0.41 10.5 0.0 2.4 3 0 0 3 3 3 0 Region in Clathrin and VPS PQQ_3 PF13570.6 EGO25304.1 - 0.047 14.2 0.1 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain DUF3510 PF12022.8 EGO25305.1 - 3.5e-27 95.3 0.0 1.5e-26 93.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 EGO25305.1 - 1.1e-26 93.5 2.2 1.1e-26 93.5 2.2 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EGO25305.1 - 0.0032 17.5 0.2 0.014 15.5 0.2 2.2 1 1 0 1 1 1 1 Vps51/Vps67 Spc7 PF08317.11 EGO25305.1 - 0.11 11.3 5.2 0.053 12.4 1.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2490 PF10677.9 EGO25305.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) FlaC_arch PF05377.11 EGO25305.1 - 0.69 10.3 2.8 1.1 9.7 0.2 2.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Voltage_CLC PF00654.20 EGO25307.1 - 1.8e-91 307.1 21.0 1.8e-91 307.1 21.0 2.3 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGO25307.1 - 0.012 16.1 0.1 0.39 11.2 0.0 2.5 2 0 0 2 2 2 0 CBS domain Cauli_VI PF01693.16 EGO25308.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin LSM PF01423.22 EGO25309.1 - 1.6e-14 53.4 0.2 2.1e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 EGO25309.1 - 0.017 15.2 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain E3_binding PF02817.17 EGO25309.1 - 0.025 14.9 0.1 0.064 13.6 0.1 1.7 1 0 0 1 1 1 0 e3 binding domain SM-ATX PF14438.6 EGO25309.1 - 0.042 14.0 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF1674 PF07896.12 EGO25310.1 - 9.9e-17 61.2 1.5 1.6e-16 60.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.18 EGO25312.1 - 1e-18 67.3 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 EGO25312.1 - 0.074 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain CbiN PF02553.15 EGO25312.1 - 0.14 12.2 0.2 0.35 10.9 0.2 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN F-box-like PF12937.7 EGO25313.1 - 0.00021 21.1 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.7 EGO25314.1 - 2.7e-09 37.8 0.0 3.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO25314.1 - 0.0001 22.5 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family BAF250_C PF12031.8 EGO25316.1 - 0.026 13.8 0.2 0.037 13.3 0.2 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa CENP-I PF07778.11 EGO25316.1 - 0.35 9.5 2.2 0.59 8.8 2.2 1.4 1 1 0 1 1 1 0 Mis6 DUF3435 PF11917.8 EGO25317.1 - 0.0012 17.8 0.1 0.0014 17.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) BTB PF00651.31 EGO25318.1 - 8.8e-11 42.0 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain GCSF PF16647.5 EGO25318.1 - 0.2 11.5 0.1 0.57 10.0 0.0 1.7 2 0 0 2 2 2 0 Granulocyte colony-stimulating factor RhoGAP PF00620.27 EGO25319.1 - 6.3e-43 146.2 0.1 2e-42 144.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 EGO25319.1 - 2.9e-06 27.1 10.8 4.5e-06 26.4 10.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGO25319.1 - 0.0027 18.0 3.9 0.0027 18.0 3.9 2.1 2 0 0 2 2 1 1 C1 domain Macoilin PF09726.9 EGO25319.1 - 0.27 9.7 13.9 0.41 9.2 13.9 1.3 1 0 0 1 1 1 0 Macoilin family zf-C5HC2 PF02928.16 EGO25319.1 - 0.35 11.3 7.7 0.71 10.3 7.7 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger zf-RING_7 PF02591.15 EGO25319.1 - 0.56 10.4 2.4 25 5.1 1.3 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain TMF_TATA_bd PF12325.8 EGO25319.1 - 1.1 9.5 19.1 0.076 13.2 3.0 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EGO25319.1 - 2.6 7.3 17.2 30 3.8 17.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cor1 PF04803.12 EGO25319.1 - 3.2 8.0 7.5 23 5.2 0.3 3.2 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region 4HB_MCP_1 PF12729.7 EGO25319.1 - 4.2 6.9 9.0 7 6.1 4.4 2.7 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction CENP-H PF05837.12 EGO25319.1 - 5 7.6 18.0 0.092 13.2 1.2 3.4 2 1 3 5 5 5 0 Centromere protein H (CENP-H) MerR-DNA-bind PF09278.11 EGO25319.1 - 6 7.5 9.8 29 5.3 1.4 4.0 2 1 1 3 3 3 0 MerR, DNA binding YabA PF06156.13 EGO25319.1 - 7.5 7.3 12.5 0.33 11.6 1.9 3.3 2 1 1 3 3 3 0 Initiation control protein YabA PHD PF00628.29 EGO25319.1 - 9.7 6.2 9.2 19 5.3 9.2 1.4 1 0 0 1 1 1 0 PHD-finger KTI12 PF08433.10 EGO25320.1 - 4.1e-82 275.7 0.0 4.7e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGO25320.1 - 1.4e-06 28.5 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO25320.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3419 PF11899.8 EGO25321.1 - 6.6e-143 476.5 0.0 8.2e-143 476.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 EGO25321.1 - 3e-09 37.5 0.0 4.9e-07 30.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO25321.1 - 3.4e-09 37.2 0.0 8.5e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGO25321.1 - 8e-08 32.3 0.0 3.4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO25321.1 - 1e-07 32.6 0.0 3.7e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO25321.1 - 2.7e-07 30.2 0.0 1.1e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGO25321.1 - 4.3e-05 23.3 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGO25321.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase HAD_2 PF13419.6 EGO25322.1 - 8.2e-22 78.1 0.0 1.2e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO25322.1 - 1.9e-12 47.9 0.0 3.8e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGO25322.1 - 0.0089 16.1 0.0 0.55 10.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO25322.1 - 0.053 13.9 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGO25322.1 - 0.088 12.5 0.0 5.1 6.7 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BRO1 PF03097.18 EGO25323.1 - 9.8e-24 83.9 0.0 1.3e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain PRP9_N PF16958.5 EGO25323.1 - 0.49 10.4 3.1 0.86 9.6 0.5 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus HTH_psq PF05225.16 EGO25324.1 - 0.00034 20.3 0.1 0.00063 19.4 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SAP PF02037.27 EGO25324.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 SAP domain UTP25 PF06862.12 EGO25325.1 - 1.7e-165 551.4 0.2 2e-165 551.1 0.2 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Plavaka PF18759.1 EGO25327.1 - 9.6e-41 140.1 0.1 9.6e-41 140.1 0.1 2.1 2 0 0 2 2 2 1 Plavaka transposase FrhB_FdhB_C PF04432.13 EGO25327.1 - 0.18 11.6 2.2 0.48 10.2 0.1 2.5 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus MFS_1 PF07690.16 EGO25330.1 - 4.7e-33 114.6 29.8 8.1e-33 113.8 29.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MARVEL PF01284.23 EGO25330.1 - 2 8.5 20.5 1.3 9.1 2.0 3.5 2 2 1 3 3 3 0 Membrane-associating domain MMS1_N PF10433.9 EGO25331.1 - 7.7e-161 536.0 0.0 1e-160 535.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGO25331.1 - 1.8e-93 313.4 0.0 1e-92 310.9 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region OsmC PF02566.19 EGO25332.1 - 2.7e-12 47.0 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Malate_synthase PF01274.22 EGO25333.1 - 3.6e-196 652.5 0.0 4.3e-196 652.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EGO25333.1 - 0.025 13.7 0.0 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family CHD5 PF04420.14 EGO25334.1 - 6.2e-59 198.4 2.2 8.4e-59 198.0 2.2 1.2 1 0 0 1 1 1 1 CHD5-like protein Melittin PF01372.17 EGO25334.1 - 0.11 12.5 2.1 1.5 8.9 0.4 2.7 2 0 0 2 2 2 0 Melittin Ribosomal_L39 PF00832.20 EGO25335.1 - 6e-23 80.2 9.9 6.9e-23 80.0 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 EGO25335.1 - 0.049 13.2 0.5 0.048 13.2 0.5 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 FKBP_C PF00254.28 EGO25336.1 - 6.3e-33 113.0 0.0 7.7e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase US30 PF17624.2 EGO25337.1 - 0.025 13.7 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function GHMP_kinases_N PF00288.26 EGO25338.1 - 5.1e-14 52.3 1.4 1.5e-13 50.7 1.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO25338.1 - 4.5e-10 39.8 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.18 EGO25339.1 - 3.8e-65 220.2 25.8 4.5e-65 220.0 25.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fe_hyd_lg_C PF02906.14 EGO25343.1 - 7.6e-50 169.8 0.0 1e-49 169.5 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.19 EGO25345.1 - 1.5e-15 56.9 0.3 2.9e-15 56.0 0.3 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGO25345.1 - 1.5e-06 28.0 0.5 2.5e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 Syntaxin FR47 PF08445.10 EGO25346.1 - 1.4e-05 25.0 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EGO25346.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Gly_acyl_tr_C PF08444.10 EGO25346.1 - 0.0056 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_10 PF13673.7 EGO25346.1 - 0.048 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO25346.1 - 0.056 13.9 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YccF PF03733.13 EGO25347.1 - 3.4 8.5 8.9 6.8 7.5 8.9 1.4 1 0 0 1 1 1 0 Inner membrane component domain Peptidase_C1_2 PF03051.15 EGO25348.1 - 5.1e-160 533.0 0.0 5.9e-160 532.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EGO25348.1 - 7.8e-07 29.4 0.0 0.046 13.8 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 EGO25348.1 - 0.025 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family FAD_binding_3 PF01494.19 EGO25349.1 - 2.3e-64 217.8 0.0 9.7e-52 176.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EGO25349.1 - 5.4e-06 25.8 0.1 1.8e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO25349.1 - 0.0001 22.5 0.1 0.00034 20.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO25349.1 - 0.00016 21.1 0.1 0.0016 17.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO25349.1 - 0.0002 20.2 0.3 0.00051 18.8 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGO25349.1 - 0.00055 19.6 0.7 0.0026 17.4 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO25349.1 - 0.00063 19.1 0.1 0.0012 18.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EGO25349.1 - 0.0011 19.5 0.5 0.33 11.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO25349.1 - 0.0033 16.6 0.1 0.0051 16.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGO25349.1 - 0.0039 16.6 0.1 0.0061 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO25349.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO25349.1 - 0.08 12.9 0.5 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EGO25350.1 - 7.6e-40 137.6 1.7 8.8e-40 137.4 1.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO25350.1 - 0.00046 20.4 0.5 0.0011 19.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO25350.1 - 0.031 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.27 EGO25351.1 - 2.4e-56 187.7 0.3 2.2e-17 62.7 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO25351.1 - 0.18 10.9 0.1 0.48 9.5 0.0 1.7 2 0 0 2 2 2 0 Gammaproteobacterial serine protease SGL PF08450.12 EGO25352.1 - 9.6e-06 25.3 0.3 1.7e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EGO25352.1 - 0.00037 20.6 0.0 0.0037 17.4 0.0 2.6 3 0 0 3 3 3 1 Arylesterase DUF1942 PF09167.11 EGO25352.1 - 0.013 15.4 0.0 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) DUF1890 PF09001.11 EGO25352.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Na_H_Exchanger PF00999.21 EGO25353.1 - 6.9e-51 173.2 27.4 8e-51 173.0 27.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EGO25353.1 - 3.3 7.9 12.3 0.28 11.3 0.2 3.5 4 0 0 4 4 4 0 YrhC-like protein Ssl1 PF04056.14 EGO25355.1 - 1.2e-70 237.2 0.0 1.7e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EGO25355.1 - 7.2e-15 55.0 11.3 7.2e-15 55.0 11.3 3.0 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 EGO25355.1 - 1.2e-11 45.2 0.0 2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EGO25355.1 - 0.0015 18.1 5.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 Tcp11 PF05794.13 EGO25356.1 - 1.3e-19 70.6 0.8 6.3e-19 68.4 0.8 1.9 1 1 0 1 1 1 1 T-complex protein 11 KRBA1 PF15287.6 EGO25356.1 - 2.4 7.9 7.7 2.2 8.1 0.1 3.9 3 0 0 3 3 3 0 KRBA1 family repeat Mg_trans_NIPA PF05653.14 EGO25357.1 - 5e-17 61.9 13.0 3.5e-09 36.2 2.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGO25357.1 - 3.3e-05 24.1 26.0 0.00054 20.1 7.8 3.5 3 1 0 3 3 3 2 EamA-like transporter family DUF3169 PF11368.8 EGO25357.1 - 0.014 14.9 3.9 0.11 12.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF3245 PF11595.8 EGO25357.1 - 5.8 7.4 12.1 1.1 9.7 7.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) DUF262 PF03235.14 EGO25359.1 - 3.1e-15 57.0 0.1 6.5e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF262 YfkB PF08756.10 EGO25359.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 YfkB-like domain Cation_efflux PF01545.21 EGO25360.1 - 1.3e-45 155.6 2.7 1.8e-45 155.1 2.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGO25360.1 - 1.7e-07 31.2 0.5 3.4e-07 30.3 0.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Zip PF02535.22 EGO25360.1 - 0.028 13.6 4.6 0.19 10.9 1.9 2.5 3 0 0 3 3 3 0 ZIP Zinc transporter SelP_N PF04592.14 EGO25360.1 - 9.1 5.6 12.0 19 4.6 12.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Fe-ADH PF00465.19 EGO25361.1 - 2.2e-68 230.8 0.0 2.7e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGO25361.1 - 1.3e-17 64.4 0.0 2.2e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Flavin_Reduct PF01613.18 EGO25363.1 - 3.8e-22 79.0 0.3 6.1e-22 78.3 0.3 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EGO25363.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Pkinase PF00069.25 EGO25365.1 - 2.2e-60 204.3 0.1 2.7e-60 204.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25365.1 - 5.2e-17 62.0 0.2 1.2e-16 60.9 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGO25365.1 - 2.2e-07 31.1 0.8 0.0002 21.4 0.4 2.5 2 1 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO25365.1 - 8.1e-05 21.6 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EGO25365.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EGO25365.1 - 0.043 13.1 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGO25365.1 - 0.21 10.9 0.8 0.62 9.4 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cellulase PF00150.18 EGO25367.1 - 9.2e-23 81.1 9.4 1.2e-22 80.7 9.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EGO25367.1 - 0.00074 18.7 0.0 0.0022 17.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EGO25367.1 - 0.035 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase DUF2610 PF11020.8 EGO25367.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) COG5 PF10392.9 EGO25368.1 - 2.3e-28 99.0 1.8 1.1e-27 96.8 0.7 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EGO25368.1 - 1.2e-05 25.2 1.6 8.6e-05 22.5 0.5 3.0 2 1 0 2 2 2 1 Vps51/Vps67 Occludin_ELL PF07303.13 EGO25368.1 - 0.05 14.3 1.0 0.41 11.4 0.1 2.8 2 1 0 2 2 2 0 Occludin homology domain COG2 PF06148.11 EGO25368.1 - 0.06 13.4 1.6 0.61 10.2 1.3 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 EGO25368.1 - 0.061 13.2 2.2 0.088 12.7 0.8 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain FlaC_arch PF05377.11 EGO25368.1 - 0.095 13.1 2.0 1 9.8 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EGO25368.1 - 3.8 7.5 6.7 1.1 9.4 1.4 2.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALS_ss_C PF10369.9 EGO25369.1 - 4.3e-20 71.7 0.1 1.7e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EGO25369.1 - 3.3e-14 52.3 0.1 5.5e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EGO25369.1 - 6.1e-08 32.4 0.3 3.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 ACT domain DUF2187 PF09953.9 EGO25369.1 - 0.041 13.9 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) UPF0058 PF01893.16 EGO25369.1 - 0.085 13.2 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 Pkinase PF00069.25 EGO25370.1 - 4.2e-10 39.4 0.2 7e-10 38.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25370.1 - 0.00065 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Proteasome PF00227.26 EGO25370.1 - 0.024 14.1 0.1 0.037 13.5 0.1 1.5 1 1 0 1 1 1 0 Proteasome subunit FTA2 PF13095.6 EGO25370.1 - 0.076 12.6 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HMG_box PF00505.19 EGO25371.1 - 2e-12 47.3 1.6 2e-12 47.3 1.6 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO25371.1 - 0.0038 17.8 0.7 0.0038 17.8 0.7 2.2 1 1 1 2 2 2 1 HMG-box domain adh_short PF00106.25 EGO25373.1 - 3.8e-25 88.5 0.2 6.9e-24 84.4 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO25373.1 - 1.6e-15 57.4 0.2 2.3e-14 53.5 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO25373.1 - 4.4e-05 23.5 0.1 7.7e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO25373.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ComGG PF14173.6 EGO25373.1 - 0.15 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ComG operon protein 7 Aldo_ket_red PF00248.21 EGO25374.1 - 4.6e-45 154.1 0.1 1.2e-37 129.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family KH_1 PF00013.29 EGO25375.1 - 1.4e-89 293.9 29.2 1.1e-13 50.8 0.3 13.9 14 2 0 14 14 14 12 KH domain SLS PF14611.6 EGO25375.1 - 5.5e-10 39.4 16.2 0.074 12.9 0.0 7.7 6 2 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EGO25375.1 - 7.2e-10 38.6 21.3 0.1 12.4 0.1 8.4 8 1 0 8 8 8 5 KH domain KH_5 PF13184.6 EGO25375.1 - 0.0015 18.6 11.5 1.6 8.9 0.6 5.9 4 1 1 5 5 5 2 NusA-like KH domain DUF4974 PF16344.5 EGO25375.1 - 0.0097 15.9 0.2 0.56 10.2 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4974) KH_4 PF13083.6 EGO25375.1 - 0.011 15.6 12.2 3.8 7.4 0.0 6.9 8 0 0 8 8 8 0 KH domain PXA PF02194.15 EGO25375.1 - 0.059 13.3 0.0 4.9 7.1 0.0 2.7 2 0 0 2 2 2 0 PXA domain RRM_1 PF00076.22 EGO25376.1 - 3e-10 39.8 0.0 2e-07 30.7 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EGO25376.1 - 5e-08 32.8 0.1 1.5e-07 31.3 0.1 1.9 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 EGO25376.1 - 0.0029 18.4 0.0 0.0078 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 EGO25376.1 - 0.069 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif NARP1 PF12569.8 EGO25376.1 - 6.8 5.5 9.2 1.1 8.0 0.2 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Metallophos PF00149.28 EGO25377.1 - 8.1e-27 95.1 0.2 1.5e-26 94.2 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGO25377.1 - 4.7e-13 49.2 0.0 7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region SLT PF01464.20 EGO25378.1 - 3e-09 36.5 0.1 5.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 EGO25378.1 - 0.019 14.7 0.4 0.03 14.0 0.4 1.3 1 1 0 1 1 1 0 Lysozyme-like Cyclin PF08613.11 EGO25381.1 - 0.0019 18.6 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGO25381.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Fungal_trans_2 PF11951.8 EGO25383.1 - 2.2e-41 142.0 2.2 7e-41 140.3 2.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO25383.1 - 2.9e-07 30.5 8.6 5.9e-07 29.5 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGO25385.1 - 6e-59 199.6 0.0 7.2e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25385.1 - 9.3e-33 113.6 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO25385.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO25385.1 - 0.063 12.6 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Apis_Csd PF11671.8 EGO25385.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Acetyltransf_1 PF00583.25 EGO25387.1 - 2.2e-13 50.5 0.0 2.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO25387.1 - 3.1e-08 33.9 0.0 4.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO25387.1 - 2.3e-06 27.6 0.0 3.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO25387.1 - 0.00064 19.6 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGO25387.1 - 0.00099 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGO25387.1 - 0.083 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_49kDa PF00346.19 EGO25387.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DNA_ligase_A_M PF01068.21 EGO25388.1 - 5.6e-40 137.2 0.1 5.6e-37 127.4 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGO25388.1 - 8.8e-35 120.6 0.0 6.4e-34 117.8 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGO25388.1 - 1.6e-16 60.7 0.0 5e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.6 EGO25389.1 - 2.5e-16 60.1 0.1 2.5e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NRN1 PF15056.6 EGO25391.1 - 0.016 15.3 0.3 0.023 14.8 0.3 1.2 1 0 0 1 1 1 0 Neuritin protein family YbaB_DNA_bd PF02575.16 EGO25392.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family PKcGMP_CC PF16808.5 EGO25392.1 - 0.13 12.1 0.8 0.27 11.1 0.8 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BolA PF01722.18 EGO25396.1 - 6.9e-30 103.1 0.2 8.1e-30 102.9 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein zf-C2H2 PF00096.26 EGO25397.1 - 3.9e-10 39.6 16.0 6.8e-07 29.4 0.5 4.1 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO25397.1 - 1.5e-08 34.7 4.5 0.00025 21.6 0.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO25397.1 - 1.2e-05 25.5 10.0 0.0027 18.1 0.2 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGO25397.1 - 0.00097 19.4 0.6 0.0024 18.1 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGO25397.1 - 0.001 18.9 1.8 0.11 12.4 0.1 2.9 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-BED PF02892.15 EGO25397.1 - 0.01 15.8 0.1 0.01 15.8 0.1 2.5 3 0 0 3 3 3 0 BED zinc finger zf-C2HE PF16278.5 EGO25397.1 - 0.019 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EGO25397.1 - 0.021 15.2 0.5 0.021 15.2 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3268 PF11672.8 EGO25397.1 - 0.053 13.9 0.1 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_6 PF13912.6 EGO25397.1 - 0.061 13.3 5.4 0.077 13.0 0.7 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO25397.1 - 5.5 6.8 7.6 8 6.3 0.2 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type Pkinase PF00069.25 EGO25398.1 - 7.6e-58 195.9 0.0 2.1e-38 132.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25398.1 - 2.2e-24 86.1 0.0 3e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO25398.1 - 3.8e-05 23.2 0.1 0.00098 18.5 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EGO25398.1 - 0.0091 15.9 1.7 0.0091 15.9 1.7 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO25398.1 - 0.024 13.6 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGO25398.1 - 0.24 10.4 0.1 0.36 9.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Homeodomain PF00046.29 EGO25399.1 - 6.1e-16 58.0 3.9 1.5e-15 56.8 3.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGO25399.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain ABC_tran PF00005.27 EGO25400.1 - 1.7e-48 164.6 0.0 1.5e-27 96.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO25400.1 - 1.6e-13 51.2 3.0 0.0088 15.9 0.2 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO25400.1 - 3.9e-12 46.1 0.0 0.00014 21.4 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EGO25400.1 - 1.4e-10 40.9 0.1 2.9e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EGO25400.1 - 7.7e-07 29.8 0.0 0.011 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGO25400.1 - 2.3e-06 27.2 1.6 0.05 13.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EGO25400.1 - 4.7e-06 26.6 0.1 0.00064 19.7 0.0 2.7 3 0 0 3 3 2 1 NACHT domain MMR_HSR1 PF01926.23 EGO25400.1 - 9.7e-06 25.7 0.0 0.026 14.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGO25400.1 - 1.8e-05 25.0 0.2 0.11 12.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGO25400.1 - 3.6e-05 24.3 0.0 0.14 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EGO25400.1 - 6.1e-05 23.2 0.1 0.35 10.9 0.0 2.8 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_33 PF13671.6 EGO25400.1 - 0.00011 22.4 0.0 0.048 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGO25400.1 - 0.00012 22.0 0.1 0.084 12.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 EGO25400.1 - 0.00015 22.1 0.0 0.59 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO25400.1 - 0.00043 20.7 0.4 1.3 9.4 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 EGO25400.1 - 0.00071 18.6 0.5 0.5 9.3 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB HEAT PF02985.22 EGO25400.1 - 0.0017 18.4 5.1 2.8 8.4 0.1 5.4 5 0 0 5 5 4 1 HEAT repeat AAA_24 PF13479.6 EGO25400.1 - 0.0018 18.1 0.0 2.2 8.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGO25400.1 - 0.0059 16.4 0.1 3.1 7.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 EGO25400.1 - 0.014 15.6 0.0 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EGO25400.1 - 0.014 15.7 0.0 6.5 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.6 EGO25400.1 - 0.015 14.0 0.0 0.96 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO25400.1 - 0.017 15.1 0.1 8.3 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGO25400.1 - 0.023 14.4 0.2 2.7 7.6 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 EGO25400.1 - 0.025 14.3 0.1 9 6.0 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EGO25400.1 - 0.027 13.7 0.0 0.089 11.9 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit HEAT_2 PF13646.6 EGO25400.1 - 0.037 14.4 6.7 11 6.5 0.1 5.1 2 1 3 5 5 5 0 HEAT repeats MMS19_C PF12460.8 EGO25400.1 - 0.041 13.0 0.3 0.52 9.4 0.1 2.2 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Dynamin_N PF00350.23 EGO25400.1 - 0.069 13.2 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 EGO25400.1 - 0.082 12.8 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 EGO25400.1 - 0.093 12.5 0.0 8.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IFRD PF05004.13 EGO25400.1 - 0.098 11.7 0.2 0.21 10.7 0.2 1.6 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Arf PF00025.21 EGO25400.1 - 0.1 12.1 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 EGO25400.1 - 0.11 12.1 0.1 19 4.8 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EGO25400.1 - 0.11 11.6 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_27 PF13514.6 EGO25400.1 - 0.12 12.0 0.0 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO25400.1 - 0.12 11.9 0.0 4 6.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region UME PF08064.13 EGO25400.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain HEAT_EZ PF13513.6 EGO25400.1 - 0.23 12.0 7.8 0.26 11.8 0.5 4.2 3 1 1 4 4 4 0 HEAT-like repeat Zeta_toxin PF06414.12 EGO25400.1 - 0.24 10.7 0.7 5.8 6.1 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin DUF3584 PF12128.8 EGO25400.1 - 0.24 8.9 1.4 4.1 4.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Glyco_hydro_18 PF00704.28 EGO25402.1 - 2.2e-82 277.3 1.2 3e-82 276.8 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DIRP PF06584.13 EGO25403.1 - 0.024 14.8 2.4 0.03 14.5 2.4 1.2 1 0 0 1 1 1 0 DIRP UPF0242 PF06785.11 EGO25403.1 - 0.54 10.3 10.6 0.66 10.1 10.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EGO25403.1 - 4.1 6.6 5.8 4.6 6.4 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein CBFB_NFYA PF02045.15 EGO25403.1 - 9.4 7.0 8.5 28 5.4 8.5 2.0 1 1 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ARA70 PF12489.8 EGO25405.1 - 0.061 13.5 2.2 0.11 12.6 2.2 1.4 1 0 0 1 1 1 0 Nuclear coactivator BORG_CEP PF14957.6 EGO25405.1 - 0.074 14.2 3.0 0.13 13.5 0.8 2.1 2 0 0 2 2 2 0 Cdc42 effector APC_N_CC PF16689.5 EGO25405.1 - 0.13 12.3 2.0 0.39 10.8 2.0 1.8 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain GTP_EFTU PF00009.27 EGO25406.1 - 1.3e-17 63.9 0.0 3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGO25406.1 - 1.3e-05 25.5 3.3 3e-05 24.3 0.7 3.1 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGO25406.1 - 2.1e-05 24.8 0.5 5.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain ABC_tran PF00005.27 EGO25406.1 - 0.18 12.3 1.7 5.4 7.5 0.0 3.0 3 1 0 3 3 3 0 ABC transporter Form_Nir_trans PF01226.17 EGO25408.1 - 5.1e-78 261.7 19.8 6e-78 261.4 19.8 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter MFS_MOT1 PF16983.5 EGO25408.1 - 1.7 9.1 9.4 0.94 9.9 3.0 2.6 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Abhydrolase_3 PF07859.13 EGO25409.1 - 2.6e-24 86.3 0.0 5.2e-24 85.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO25409.1 - 8.8e-13 47.8 0.0 1.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3128 PF11326.8 EGO25410.1 - 1.4e-24 86.2 1.0 2.2e-24 85.6 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MCM PF00493.23 EGO25411.1 - 1.3e-99 331.8 0.0 1.9e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO25411.1 - 3e-38 130.5 0.0 5.2e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EGO25411.1 - 3.2e-27 95.7 21.5 6.2e-27 94.8 19.3 2.5 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EGO25411.1 - 1.9e-26 92.3 2.1 3.2e-26 91.6 0.8 2.2 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO25411.1 - 1.1e-13 51.6 0.0 3.7e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO25411.1 - 1.2e-07 31.3 0.0 3e-06 26.7 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO25411.1 - 6.4e-06 26.2 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SelR PF01641.18 EGO25411.1 - 0.00079 19.5 0.2 0.35 11.0 0.1 2.4 2 0 0 2 2 2 2 SelR domain AAA_3 PF07726.11 EGO25411.1 - 0.0011 18.9 0.1 0.025 14.5 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO25411.1 - 0.0039 16.9 0.1 0.026 14.2 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 EGO25411.1 - 0.031 14.5 0.1 0.066 13.4 0.1 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cellulase PF00150.18 EGO25412.1 - 3e-31 108.9 6.0 4e-31 108.5 6.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EGO25412.1 - 4.5e-13 48.9 9.4 4.5e-13 48.9 9.4 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 EGO25412.1 - 0.00061 19.0 0.1 0.0017 17.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EGO25412.1 - 0.048 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase Cellulase PF00150.18 EGO25413.1 - 3.2e-25 89.1 10.4 3.9e-25 88.8 10.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EGO25413.1 - 7.1e-05 22.1 0.0 0.00015 21.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EGO25413.1 - 0.013 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase adh_short PF00106.25 EGO25414.1 - 4.2e-34 117.7 0.0 5.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO25414.1 - 1.7e-25 90.0 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO25414.1 - 1.4e-08 34.8 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO25414.1 - 0.00037 20.4 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO25414.1 - 0.00056 19.4 0.0 0.0016 17.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_50 PF18024.1 EGO25414.1 - 0.0042 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Ferrochelatase PF00762.19 EGO25416.1 - 4.5e-100 334.8 0.0 5.1e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CPSase_sm_chain PF00988.22 EGO25417.1 - 4.2e-44 149.5 0.0 6.4e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGO25417.1 - 5.1e-37 127.5 0.0 7e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGO25417.1 - 9.4e-09 35.3 0.3 2e-07 31.0 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EGO25417.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family BSD PF03909.17 EGO25418.1 - 3e-12 46.3 0.2 7.7e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 BSD domain KfrA_N PF11740.8 EGO25418.1 - 0.02 15.5 0.3 0.02 15.5 0.3 3.0 3 1 0 3 3 3 0 Plasmid replication region DNA-binding N-term T3SSipB PF16535.5 EGO25418.1 - 0.15 12.5 4.4 0.22 12.0 1.0 2.5 2 1 1 3 3 3 0 Type III cell invasion protein SipB DUF4898 PF16239.5 EGO25419.1 - 0.13 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) Scs3p PF10261.9 EGO25420.1 - 3.3e-42 144.7 0.0 4.1e-33 114.9 0.0 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 EGO25420.1 - 6.5 6.5 12.5 0.035 13.9 1.2 2.4 3 0 0 3 3 3 0 PAP2 superfamily Methyltrn_RNA_3 PF02598.17 EGO25421.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Putative RNA methyltransferase Pro_isomerase PF00160.21 EGO25422.1 - 2.1e-47 161.4 0.2 2.6e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 EGO25423.1 - 4.5e-39 134.0 0.0 8.5e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EGO25423.1 - 2e-17 63.2 0.4 3.5e-17 62.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EGO25423.1 - 5.6e-16 58.9 0.0 7.2e-15 55.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO25423.1 - 0.0003 20.8 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EGO25425.1 - 6.8e-08 32.2 15.8 1.1e-07 31.6 15.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO25425.1 - 2.8e-07 30.8 14.2 4.1e-07 30.2 14.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGO25425.1 - 5.5e-06 26.2 16.2 9.4e-06 25.4 16.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO25425.1 - 9.6e-06 25.5 14.3 1.6e-05 24.8 14.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 EGO25425.1 - 1.2e-05 25.0 8.1 2.3e-05 24.1 8.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 EGO25425.1 - 0.00011 22.0 9.5 0.00016 21.5 9.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO25425.1 - 0.00021 21.2 13.5 0.00031 20.6 13.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGO25425.1 - 0.00061 20.0 13.2 0.0017 18.6 13.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGO25425.1 - 0.015 15.5 11.4 0.026 14.7 11.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGO25425.1 - 0.019 15.1 9.4 0.032 14.4 9.4 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EGO25425.1 - 0.032 14.1 3.9 0.051 13.4 3.9 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGO25425.1 - 0.13 12.4 7.5 0.35 11.0 7.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Foamy_BEL PF03274.14 EGO25426.1 - 0.00054 19.4 0.0 0.00057 19.3 0.0 1.0 1 0 0 1 1 1 1 Foamy virus BEL 1/2 protein Homeodomain PF00046.29 EGO25427.1 - 3.8e-18 65.1 2.2 6.4e-18 64.4 2.2 1.4 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 EGO25428.1 - 3e-36 125.1 0.0 5.5e-36 124.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25428.1 - 5.4e-22 78.3 0.0 1.9e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO25428.1 - 0.051 13.5 0.2 4.4 7.2 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO25428.1 - 0.085 12.1 0.1 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like ALAD PF00490.21 EGO25430.1 - 1.1e-121 405.9 0.0 1.4e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-rbx1 PF12678.7 EGO25431.1 - 3e-09 37.0 3.6 4.9e-09 36.3 3.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain Ank_4 PF13637.6 EGO25431.1 - 6e-08 33.1 0.1 0.00057 20.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-ANAPC11 PF12861.7 EGO25431.1 - 6.8e-07 29.3 2.3 2.1e-05 24.5 4.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ank_5 PF13857.6 EGO25431.1 - 8.1e-07 29.2 0.1 2e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 EGO25431.1 - 4.2e-06 27.0 9.0 5.7e-05 23.4 9.0 2.1 1 1 0 1 1 1 1 Ring finger domain Ank_3 PF13606.6 EGO25431.1 - 9.3e-06 25.6 0.0 0.00013 22.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EGO25431.1 - 5.6e-05 23.6 0.0 9.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO25431.1 - 0.00019 21.7 0.1 0.0012 19.1 0.1 2.4 3 0 0 3 3 2 1 Ankyrin repeat zf-C3HC4 PF00097.25 EGO25431.1 - 0.00033 20.5 1.7 0.0019 18.0 1.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO25431.1 - 0.00064 19.5 3.4 0.019 14.8 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO25431.1 - 0.0015 18.5 2.5 0.0072 16.3 2.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO25431.1 - 0.019 15.1 1.4 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGO25431.1 - 0.038 13.9 0.9 0.21 11.6 0.9 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGO25431.1 - 0.054 13.4 1.2 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGO25431.1 - 0.26 11.5 6.5 0.79 9.9 6.6 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 EGO25431.1 - 0.37 10.6 9.1 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger HscB_4_cys PF18256.1 EGO25431.1 - 0.5 10.2 9.1 0.61 10.0 1.6 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Rpr2 PF04032.16 EGO25432.1 - 1.5e-22 79.7 0.1 3.4e-22 78.5 0.1 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_7 PF02591.15 EGO25432.1 - 0.035 14.3 0.6 0.097 12.9 0.6 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain Propeptide_C25 PF08126.11 EGO25432.1 - 0.14 11.2 0.4 0.22 10.6 0.4 1.2 1 0 0 1 1 1 0 Propeptide_C25 DPBB_1 PF03330.18 EGO25433.1 - 0.00014 22.0 0.5 0.00053 20.2 0.1 2.1 2 0 0 2 2 2 1 Lytic transglycolase Bromodomain PF00439.25 EGO25435.1 - 1.9e-24 85.5 0.1 3.9e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGO25435.1 - 5.6e-05 23.3 0.0 9.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO25435.1 - 0.00013 21.9 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO25435.1 - 0.0019 18.6 0.2 0.0036 17.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 EGO25436.1 - 2.1e-47 160.8 0.0 4.4e-47 159.7 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO25436.1 - 3.4e-18 65.6 0.0 4.2e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO25436.1 - 2.3e-05 24.6 0.0 7.9e-05 22.9 0.0 1.8 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGO25436.1 - 0.025 14.6 0.0 0.18 11.9 0.0 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGO25436.1 - 0.033 14.6 0.1 0.26 11.8 0.1 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF5029 PF16432.5 EGO25436.1 - 0.17 11.4 2.4 0.53 9.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5029) EXS PF03124.14 EGO25437.1 - 1.1e-105 353.6 6.3 1.3e-105 353.4 6.3 1.0 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.13 EGO25437.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-C2H2_jaz PF12171.8 EGO25438.1 - 2.1e-05 24.7 0.0 3.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 EGO25438.1 - 0.00016 21.6 2.2 0.00016 21.6 2.2 2.0 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-met PF12874.7 EGO25438.1 - 0.00023 21.5 0.1 0.00036 20.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EGO25438.1 - 0.016 15.3 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger Atg14 PF10186.9 EGO25438.1 - 1.7 7.6 13.8 1.4 7.9 2.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 tRNA-synt_1 PF00133.22 EGO25439.1 - 1.6e-217 723.5 0.0 2.4e-217 722.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGO25439.1 - 1.9e-26 92.8 0.1 4.4e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGO25439.1 - 2.3e-14 53.0 0.2 5.2e-05 22.2 0.1 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGO25439.1 - 0.1 11.9 0.0 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PC4 PF02229.16 EGO25440.1 - 3.7e-21 74.5 0.2 6.6e-21 73.7 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PGA2 PF07543.12 EGO25440.1 - 0.051 13.6 2.0 0.067 13.2 2.0 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 ABC1 PF03109.16 EGO25441.1 - 3.1e-31 108.0 0.0 5.9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGO25441.1 - 0.0012 18.5 0.1 0.0049 16.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family zf-CCCH PF00642.24 EGO25447.1 - 3.4e-14 52.3 16.3 4.7e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGO25447.1 - 0.0062 17.2 1.8 1.6 9.4 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 EGO25447.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 EGO25447.1 - 0.0081 16.0 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 EGO25447.1 - 0.018 15.2 4.8 0.32 11.2 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Alg14 PF08660.11 EGO25448.1 - 1.6e-53 181.3 0.0 2.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.28 EGO25449.1 - 1.6e-28 97.3 5.6 3.1e-05 23.6 1.9 7.3 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC8 PF04049.13 EGO25449.1 - 6.3e-24 84.6 0.0 1.4e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 EGO25449.1 - 1.5e-23 81.0 8.6 0.00036 20.5 0.0 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25449.1 - 6.5e-21 72.7 17.1 0.0039 17.2 0.1 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGO25449.1 - 2.6e-16 58.9 12.1 0.018 15.8 0.1 7.5 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25449.1 - 2.4e-12 46.9 16.7 0.018 15.3 0.1 6.3 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO25449.1 - 8e-11 41.4 1.2 8.8e-07 28.5 0.3 4.5 2 2 2 4 4 4 2 TPR repeat TPR_7 PF13176.6 EGO25449.1 - 1.8e-10 40.1 12.0 0.056 13.5 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGO25449.1 - 2.7e-10 40.6 5.9 0.002 18.6 0.0 6.0 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25449.1 - 3.9e-10 40.2 16.9 5e-06 27.1 1.5 6.3 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25449.1 - 2e-08 34.0 2.7 0.3 11.6 0.2 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO25449.1 - 1.1e-06 28.7 8.0 0.001 19.1 1.0 4.7 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO25449.1 - 1.8e-06 28.2 9.6 3.6 8.4 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO25449.1 - 0.00014 21.6 4.8 0.31 11.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 EGO25449.1 - 0.00044 19.4 0.0 0.32 10.0 0.0 3.2 2 2 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 EGO25449.1 - 0.00071 18.9 8.8 0.011 14.9 2.8 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO25449.1 - 0.0036 17.5 14.8 1.6 9.0 0.3 5.7 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EGO25449.1 - 0.0046 16.7 3.2 0.22 11.2 0.1 3.2 4 0 0 4 4 4 1 26S proteasome subunit RPN7 DUF3856 PF12968.7 EGO25449.1 - 0.18 11.8 4.6 1.6 8.8 0.1 3.7 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) GLTSCR1 PF15249.6 EGO25450.1 - 1.4e-26 92.9 0.1 2.5e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Rabaptin PF03528.15 EGO25450.1 - 0.045 12.5 1.1 0.067 11.9 1.1 1.2 1 0 0 1 1 1 0 Rabaptin Mito_carr PF00153.27 EGO25451.1 - 1.8e-16 59.8 0.0 9.6e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein SNF2_N PF00176.23 EGO25453.1 - 6.9e-55 186.2 0.0 1.2e-54 185.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO25453.1 - 4e-18 65.8 0.1 1.1e-17 64.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO25453.1 - 2e-07 31.2 0.0 1.2e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO25453.1 - 3.5e-05 23.1 0.6 7.3e-05 22.1 0.2 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 EGO25453.1 - 0.00065 19.9 0.0 0.0019 18.4 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif TRI12 PF06609.13 EGO25454.1 - 3.6e-09 35.6 13.5 5.2e-09 35.1 13.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EGO25454.1 - 1.4e-06 27.5 29.5 0.0003 19.8 22.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily SelK_SelG PF10961.8 EGO25454.1 - 0.12 13.0 1.0 67 4.2 0.0 3.5 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Ank_4 PF13637.6 EGO25456.1 - 5.6e-09 36.4 0.0 1.9e-06 28.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO25456.1 - 1.5e-06 28.7 0.0 2.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO25456.1 - 8.4e-06 26.0 0.1 3.1e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO25456.1 - 7.1e-05 23.1 0.0 0.002 18.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EGO25456.1 - 0.014 15.8 0.1 0.56 11.0 0.0 3.1 4 0 0 4 4 4 0 Ankyrin repeat Glyco_hydro_61 PF03443.14 EGO25457.1 - 2.5e-57 194.1 0.2 2.8e-57 194.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.12 EGO25458.1 - 2.9e-39 134.0 21.8 4.7e-39 133.3 21.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EGO25458.1 - 0.028 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic LRIF1 PF15741.5 EGO25458.1 - 1 7.8 8.6 1.2 7.6 8.6 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Ribosomal_S8e PF01201.22 EGO25459.1 - 2.2e-49 167.2 1.7 2.4e-49 167.0 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S8e Yip1 PF04893.17 EGO25460.1 - 8.9e-05 22.3 1.5 0.00012 21.9 1.5 1.2 1 0 0 1 1 1 1 Yip1 domain ITI_HC_C PF06668.12 EGO25461.1 - 0.11 12.2 0.1 17 5.0 0.0 2.8 3 0 0 3 3 3 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF1746 PF08508.10 EGO25462.1 - 1.3e-10 41.6 4.6 2.6e-10 40.7 4.6 1.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF4131 PF13567.6 EGO25462.1 - 0.16 11.7 0.8 0.33 10.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 EGO25463.1 - 3.2e-07 30.3 10.9 8.6e-07 28.9 10.9 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF2970 PF11174.8 EGO25463.1 - 0.028 14.3 0.1 0.028 14.3 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) DUF4064 PF13273.6 EGO25463.1 - 5 7.5 9.9 9.4 6.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Hist_deacetyl PF00850.19 EGO25464.1 - 8.4e-81 271.8 0.2 1.8e-80 270.7 0.2 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EGO25464.1 - 3.1e-43 147.8 0.4 3.9e-43 147.4 0.4 1.1 1 0 0 1 1 1 1 Arb2 domain Amidohydro_3 PF07969.11 EGO25465.1 - 5.6e-15 55.8 0.3 4.2e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO25465.1 - 2e-12 47.1 0.0 2.6e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Rad10 PF03834.14 EGO25466.1 - 7.7e-45 151.6 0.2 1.2e-44 150.9 0.2 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGO25466.1 - 8.2e-07 29.5 0.0 1.6e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EGO25466.1 - 0.027 14.6 0.0 0.22 11.6 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix motif DASH_Dad1 PF08649.10 EGO25466.1 - 0.14 12.4 0.6 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 Amidohydro_1 PF01979.20 EGO25467.1 - 1.1e-10 41.3 0.0 2.2e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO25467.1 - 1.1e-08 35.1 0.7 0.0015 18.1 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family TRP PF06011.12 EGO25468.1 - 1.9e-80 270.7 23.9 2.5e-80 270.3 23.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGO25468.1 - 3.5e-28 98.7 0.1 5.8e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 ML-like domain OPT PF03169.15 EGO25469.1 - 1.5e-156 522.6 48.9 1.7e-156 522.4 48.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MgsA_C PF12002.8 EGO25470.1 - 1.4e-56 191.0 0.2 2.1e-56 190.4 0.2 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGO25470.1 - 2e-18 66.5 0.6 2e-18 66.5 0.6 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 EGO25470.1 - 2.6e-16 60.2 0.0 9.2e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO25470.1 - 4e-12 46.2 0.0 7.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO25470.1 - 2.5e-09 37.2 0.0 1e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGO25470.1 - 1.1e-06 28.2 0.0 0.039 13.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGO25470.1 - 4.9e-06 27.0 0.1 0.014 15.8 0.0 2.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGO25470.1 - 2.1e-05 24.8 0.0 0.00073 19.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGO25470.1 - 4.9e-05 23.1 0.0 0.0037 17.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 EGO25470.1 - 0.00066 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO25470.1 - 0.0021 18.6 0.0 0.0054 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EGO25470.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 EGO25470.1 - 0.005 17.1 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO25470.1 - 0.0051 17.0 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGO25470.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 EGO25470.1 - 0.0056 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 EGO25470.1 - 0.0066 17.0 0.0 0.041 14.4 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 EGO25470.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGO25470.1 - 0.024 14.5 0.1 6.6 6.6 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGO25470.1 - 0.03 14.2 0.1 0.31 11.0 0.0 2.2 1 1 1 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EGO25470.1 - 0.04 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 EGO25470.1 - 0.042 13.6 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EGO25470.1 - 0.053 12.7 0.0 0.29 10.3 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain SKI PF01202.22 EGO25470.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Rad17 PF03215.15 EGO25470.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NTP_transferase PF00483.23 EGO25471.1 - 1.6e-08 34.5 0.0 2.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGO25471.1 - 2.3e-07 31.3 0.0 3.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGO25471.1 - 0.0013 18.4 4.2 0.14 11.9 2.5 3.2 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGO25471.1 - 0.013 13.6 1.1 0.019 13.2 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EGO25471.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase RXT2_N PF08595.11 EGO25471.1 - 3.4 7.7 6.8 6.2 6.8 6.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EGO25471.1 - 3.6 5.7 10.9 5.6 5.1 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family Hexapep_2 PF14602.6 EGO25471.1 - 3.9 7.3 6.1 16 5.3 0.1 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase eIF-3c_N PF05470.12 EGO25472.1 - 1.4e-184 614.8 21.3 1.4e-184 614.8 21.3 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGO25472.1 - 1.1e-13 51.6 1.1 3.5e-13 50.0 0.0 2.5 3 0 0 3 3 3 1 PCI domain DUF5378 PF17349.2 EGO25472.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) ARD PF03079.14 EGO25473.1 - 2.5e-44 151.2 0.3 3e-44 151.0 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGO25473.1 - 3.4e-09 36.3 0.2 7.3e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGO25473.1 - 6.4e-07 29.4 0.1 9.2e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGO25473.1 - 0.0017 18.0 0.0 0.0038 16.8 0.0 1.6 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.12 EGO25473.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) OSCP PF00213.18 EGO25475.1 - 7.8e-40 136.8 0.6 9e-40 136.6 0.6 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Peptidase_C15 PF01470.17 EGO25476.1 - 7e-10 39.4 0.0 0.0018 18.5 0.0 2.6 3 0 0 3 3 3 2 Pyroglutamyl peptidase APS_kinase PF01583.20 EGO25477.1 - 9.2e-72 240.1 0.0 1.1e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EGO25477.1 - 6.2e-06 26.4 0.0 8.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO25477.1 - 0.00046 20.7 0.0 0.00085 19.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 EGO25477.1 - 0.019 14.7 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 EGO25477.1 - 0.03 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HisKA_3 PF07730.13 EGO25477.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase Pkinase PF00069.25 EGO25480.1 - 1.1e-64 218.3 0.0 1.3e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25480.1 - 1.6e-48 165.3 0.0 2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO25480.1 - 1.8e-06 27.0 0.0 3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO25480.1 - 7.5e-05 22.8 0.0 0.38 10.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO25480.1 - 0.0003 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGO25480.1 - 0.0041 16.7 0.1 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EGO25480.1 - 0.0096 14.9 0.0 0.056 12.4 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain REV PF00424.18 EGO25480.1 - 0.19 11.8 1.9 0.45 10.6 0.7 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) BAR PF03114.18 EGO25483.1 - 1.3e-49 169.0 1.0 1.5e-49 168.8 1.0 1.0 1 0 0 1 1 1 1 BAR domain SYF2 PF08231.12 EGO25483.1 - 0.0015 18.9 1.4 0.0029 18.0 1.4 1.6 1 1 0 1 1 1 1 SYF2 splicing factor EzrA PF06160.12 EGO25483.1 - 0.015 13.5 2.3 0.49 8.5 0.2 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF3987 PF13148.6 EGO25485.1 - 0.0062 15.6 5.5 0.0067 15.5 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) DNA_pol3_a_NII PF11490.8 EGO25485.1 - 2.4 8.1 10.8 3.3 7.6 10.8 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RHD3 PF05879.12 EGO25487.1 - 3.3e-245 815.8 0.7 2e-244 813.2 0.7 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EGO25487.1 - 4.3e-06 26.2 0.2 8.9e-06 25.1 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGO25487.1 - 7.4e-06 26.0 0.0 2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGO25487.1 - 4e-05 23.7 0.0 7.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EGO25487.1 - 0.0021 18.3 0.0 0.0054 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AMP-binding PF00501.28 EGO25489.1 - 3.6e-40 137.9 0.0 5.1e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGO25489.1 - 1.8e-06 27.8 0.1 3.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGO25489.1 - 0.096 13.7 0.0 0.27 12.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glutaredoxin PF00462.24 EGO25492.1 - 2.2e-09 37.4 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Glyco_hydro_35 PF01301.19 EGO25493.1 - 2.7e-65 221.1 2.3 9.5e-65 219.3 0.5 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EGO25493.1 - 9.9e-58 193.7 10.0 4.4e-32 111.0 0.8 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EGO25493.1 - 3.1e-54 183.6 4.9 7e-54 182.4 4.9 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EGO25493.1 - 3.1e-20 71.5 0.0 1.2e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EGO25493.1 - 0.0098 15.4 0.1 0.049 13.0 0.0 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) YecM PF06185.12 EGO25493.1 - 0.12 12.1 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 YecM protein CMAS PF02353.20 EGO25496.1 - 1.5e-31 109.7 0.3 2.1e-31 109.2 0.3 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO25496.1 - 3.5e-13 50.1 0.0 6.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO25496.1 - 1.5e-12 48.0 0.0 3.6e-12 46.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO25496.1 - 1.4e-09 37.9 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO25496.1 - 1.1e-08 35.7 0.0 4e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO25496.1 - 5.4e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO25496.1 - 4.3e-07 29.6 0.0 7.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO25496.1 - 1.1e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 EGO25496.1 - 1.6e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 EGO25496.1 - 6.1e-05 22.2 0.0 9.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 EGO25496.1 - 0.00029 20.5 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NodS PF05401.11 EGO25496.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) GidB PF02527.15 EGO25496.1 - 0.022 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 EGO25496.1 - 0.038 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MetW PF07021.12 EGO25496.1 - 0.044 13.4 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 EGO25496.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EGO25496.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MDM31_MDM32 PF08118.11 EGO25497.1 - 3e-216 719.2 0.1 3.4e-216 719.0 0.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Sugar_tr PF00083.24 EGO25498.1 - 2.2e-109 366.4 9.0 3.7e-109 365.6 9.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO25498.1 - 5.1e-18 65.1 44.8 1.7e-13 50.3 13.0 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO25498.1 - 0.0021 16.5 3.1 0.0021 16.5 3.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PBECR3 PF18812.1 EGO25499.1 - 0.022 14.7 0.2 0.022 14.7 0.2 1.9 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Bax1-I PF01027.20 EGO25500.1 - 4.2e-41 141.1 24.1 5e-41 140.8 24.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Holin_SPP1 PF04688.13 EGO25500.1 - 0.38 11.0 3.1 0.33 11.1 1.4 1.8 1 1 1 2 2 2 0 SPP1 phage holin T3SS_needle_F PF09392.10 EGO25501.1 - 0.3 11.3 2.7 4.7 7.5 0.1 3.1 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF COX4_pro_2 PF07835.12 EGO25501.1 - 1.4 9.1 2.9 1.3 9.2 0.7 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV PH_16 PF17838.1 EGO25502.1 - 0.011 15.5 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 PH domain KxDL PF10241.9 EGO25502.1 - 0.29 11.4 2.5 0.52 10.6 2.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Spc7 PF08317.11 EGO25502.1 - 0.49 9.2 8.0 0.68 8.8 8.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Glyco_hydro_92 PF07971.12 EGO25503.1 - 3.9e-120 401.9 2.6 4.7e-120 401.6 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGO25503.1 - 1.7e-52 178.7 0.2 3.2e-52 177.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Pept_tRNA_hydro PF01195.19 EGO25504.1 - 2.1e-30 105.9 0.0 2.5e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase HlyIII PF03006.20 EGO25505.1 - 6.1e-40 137.3 17.9 8.3e-40 136.9 17.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related TFIID_20kDa PF03847.13 EGO25506.1 - 2.2e-27 95.3 0.1 3.7e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EGO25506.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_pp85 PF04637.12 EGO25506.1 - 0.066 11.6 0.2 0.11 11.0 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Histone PF00125.24 EGO25506.1 - 0.072 13.4 0.2 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 AFG1_ATPase PF03969.16 EGO25507.1 - 4.2e-60 203.6 0.0 1.4e-54 185.4 0.0 3.5 3 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 EGO25507.1 - 5.9e-08 33.3 0.0 2.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGO25507.1 - 0.0029 17.3 0.3 0.0091 15.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO25507.1 - 0.0046 17.2 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGO25507.1 - 0.032 14.0 0.0 8 6.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGO25507.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EGO25507.1 - 0.08 13.3 0.1 0.77 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain HSP20 PF00011.21 EGO25508.1 - 0.043 14.0 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 Hsp20/alpha crystallin family zf-CCHC PF00098.23 EGO25511.1 - 2.6e-09 36.7 0.9 3.8e-09 36.2 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO25511.1 - 0.0048 16.7 0.4 0.0071 16.2 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO25511.1 - 0.012 15.4 2.3 0.018 14.9 2.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO25511.1 - 0.028 14.4 1.0 0.053 13.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EGO25511.1 - 0.035 13.8 2.5 0.068 12.9 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf_C2H2_13 PF18508.1 EGO25511.1 - 0.042 13.4 0.2 0.059 13.0 0.2 1.3 1 0 0 1 1 1 0 Zinc finger domain Plavaka PF18759.1 EGO25512.1 - 2.2e-33 115.9 0.4 2.9e-33 115.5 0.4 1.0 1 0 0 1 1 1 1 Plavaka transposase TAN PF11640.8 EGO25512.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Acetyltransf_1 PF00583.25 EGO25513.1 - 6.6e-05 23.1 0.0 0.023 14.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO25513.1 - 0.00036 20.9 0.0 0.00056 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO25513.1 - 0.031 14.2 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.7 EGO25513.1 - 0.072 13.0 0.0 5.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO25513.1 - 0.24 11.5 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EGO25516.1 - 1.4e-20 73.8 0.0 3e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25516.1 - 4.2e-14 52.5 0.0 8.9e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EGO25516.1 - 0.0064 16.1 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGO25516.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGO25516.1 - 0.08 12.5 0.1 12 5.4 0.1 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase Asn_synthase PF00733.21 EGO25517.1 - 2e-20 73.8 0.5 8.6e-09 35.5 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EGO25517.1 - 1.2e-06 28.5 0.0 3.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 EGO25517.1 - 0.0006 19.4 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DnaJ PF00226.31 EGO25518.1 - 4.3e-10 39.6 0.2 7.9e-10 38.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain CcmD PF04995.14 EGO25518.1 - 0.38 10.9 2.4 0.67 10.1 2.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1771 PF08590.10 EGO25519.1 - 2.1e-23 82.4 3.7 2.1e-23 82.4 3.7 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGO25519.1 - 5.3e-09 36.3 0.7 1.2e-08 35.1 0.7 1.7 1 0 0 1 1 1 1 Smr domain Tho2 PF11262.8 EGO25519.1 - 0.98 8.6 7.9 1.8 7.7 6.8 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RicinB_lectin_2 PF14200.6 EGO25520.1 - 0.043 14.5 0.0 0.064 14.0 0.0 1.3 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF1771 PF08590.10 EGO25521.1 - 2.8e-23 82.1 5.4 5.2e-23 81.2 5.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGO25521.1 - 2.7e-10 40.5 0.1 5.4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Smr domain ODC_AZ PF02100.17 EGO25522.1 - 1.4e-15 57.2 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.20 EGO25523.1 - 1.3e-28 98.8 0.6 1.3e-28 98.8 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGO25523.1 - 4.4e-24 83.7 0.0 7.1e-24 83.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PACT_coil_coil PF10495.9 EGO25524.1 - 0.051 14.1 0.6 0.13 12.9 0.3 1.8 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein p450 PF00067.22 EGO25525.1 - 2.3e-61 208.0 0.0 8.5e-61 206.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 EGO25526.1 - 6.1e-08 32.8 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO25526.1 - 6.4e-08 32.4 0.0 9.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HEM4 PF02602.15 EGO25526.1 - 0.087 12.2 0.0 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD AAA_2 PF07724.14 EGO25527.1 - 3.9e-50 170.3 0.0 4.7e-46 157.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGO25527.1 - 1.1e-31 108.8 0.7 1.1e-31 108.8 0.7 3.8 3 1 1 4 4 3 1 AAA lid domain AAA PF00004.29 EGO25527.1 - 1.5e-24 86.9 0.0 7.6e-13 49.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGO25527.1 - 2e-24 85.4 0.4 8.8e-24 83.4 0.4 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGO25527.1 - 3.4e-15 56.3 0.0 7.3e-08 32.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 EGO25527.1 - 8.5e-15 54.6 11.8 5.4e-11 42.5 0.9 4.1 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 EGO25527.1 - 2.6e-11 44.2 2.9 2.2e-05 24.9 0.0 5.3 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 EGO25527.1 - 2.7e-09 37.4 0.0 0.0023 18.2 0.0 3.7 2 1 1 3 3 2 2 AAA domain Sigma54_activat PF00158.26 EGO25527.1 - 4.4e-08 33.0 0.0 5.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGO25527.1 - 1.6e-06 28.0 0.0 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 EGO25527.1 - 1.4e-05 24.6 0.0 0.045 13.1 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EGO25527.1 - 1.5e-05 24.5 0.5 0.015 14.7 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGO25527.1 - 1.8e-05 24.1 0.5 0.31 10.2 0.0 3.2 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_24 PF13479.6 EGO25527.1 - 2.7e-05 24.0 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO25527.1 - 0.00011 22.7 1.7 0.22 12.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO25527.1 - 0.00017 21.8 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO25527.1 - 0.00026 21.3 0.2 1.6 9.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 EGO25527.1 - 0.00077 19.4 0.0 0.25 11.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 EGO25527.1 - 0.00089 19.0 0.3 4.2 7.1 0.0 3.9 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EGO25527.1 - 0.0013 18.1 0.0 0.17 11.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 EGO25527.1 - 0.0014 18.1 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 EGO25527.1 - 0.0025 18.0 0.0 0.65 10.2 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EGO25527.1 - 0.0066 16.4 0.0 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGO25527.1 - 0.0075 16.5 1.8 2.2 8.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EGO25527.1 - 0.0096 16.4 0.3 3.3 8.2 0.0 3.3 3 0 0 3 3 2 1 ABC transporter PhoH PF02562.16 EGO25527.1 - 0.022 14.2 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 EGO25527.1 - 0.031 14.2 5.4 7 6.5 0.1 4.2 4 1 0 5 5 4 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGO25527.1 - 0.031 14.6 0.0 8.2 6.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGO25527.1 - 0.047 13.6 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase ResIII PF04851.15 EGO25527.1 - 0.049 13.6 0.0 1.8 8.5 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EGO25527.1 - 0.06 13.2 0.0 5.9 6.8 0.0 3.4 3 0 0 3 3 3 0 NTPase Torsin PF06309.11 EGO25527.1 - 0.074 13.1 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 2 0 Torsin CbiA PF01656.23 EGO25527.1 - 0.09 12.8 0.4 11 6.1 0.0 3.2 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_3 PF07726.11 EGO25527.1 - 0.12 12.2 0.0 42 4.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGO25527.1 - 0.13 12.0 0.1 9.7 6.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO25527.1 - 0.36 11.3 12.8 16 5.9 0.0 3.8 3 2 0 3 3 3 0 AAA domain Spc7 PF08317.11 EGO25527.1 - 1.5 7.7 11.0 3.7 6.3 11.0 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_25 PF13481.6 EGO25527.1 - 3.9 7.0 6.1 11 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain zf-Tim10_DDP PF02953.15 EGO25528.1 - 4e-22 77.6 0.3 5.5e-22 77.2 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Nucleos_tra2_C PF07662.13 EGO25529.1 - 2.2e-68 230.2 0.9 2.2e-68 230.2 0.9 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EGO25529.1 - 6e-21 74.8 5.3 6e-21 74.8 5.3 4.1 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EGO25529.1 - 0.087 13.1 14.9 0.045 14.0 6.9 3.1 2 1 0 2 2 2 0 Nucleoside recognition WD40 PF00400.32 EGO25530.1 - 8.4e-10 39.1 1.2 0.0027 18.5 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO25530.1 - 1.2e-06 28.7 0.0 0.52 10.6 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RPA_interact_C PF14768.6 EGO25531.1 - 0.0028 18.2 0.1 0.0048 17.4 0.1 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Apq12 PF12716.7 EGO25532.1 - 0.032 14.2 1.8 0.032 14.2 1.8 2.0 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis DUF5572 PF17733.1 EGO25532.1 - 4.5 7.2 6.6 1.2 9.0 1.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5572) MPC PF03650.13 EGO25533.1 - 5.1e-41 139.3 0.2 5.6e-41 139.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Palm_thioest PF02089.15 EGO25535.1 - 2.1e-83 279.9 0.0 3.9e-83 279.0 0.0 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGO25535.1 - 0.006 16.3 0.1 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 EGO25535.1 - 0.13 11.6 0.0 0.42 9.9 0.0 1.8 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF563 PF04577.14 EGO25536.1 - 6.3e-18 65.7 1.8 6e-17 62.5 0.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF563) DUF3421 PF11901.8 EGO25537.1 - 2.3e-27 95.2 1.1 2.6e-14 53.2 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DUF2076 PF09849.9 EGO25537.1 - 0.015 15.4 3.2 0.022 14.8 3.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3586 PF12131.8 EGO25539.1 - 0.054 13.7 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) CsbD PF05532.12 EGO25541.1 - 1.1e-15 57.2 14.2 3.3e-09 36.5 1.8 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 EGO25541.1 - 0.069 13.6 1.2 0.13 12.6 0.3 2.1 1 1 2 3 3 3 0 Heat shock protein 9/12 Med1 PF10744.9 EGO25542.1 - 0.037 13.1 0.5 4.1 6.3 0.1 3.1 4 0 0 4 4 4 0 Mediator of RNA polymerase II transcription subunit 1 Plavaka PF18759.1 EGO25545.1 - 9.1e-41 140.1 0.1 9.1e-41 140.1 0.1 2.1 2 0 0 2 2 2 1 Plavaka transposase EAR PF07897.11 EGO25545.1 - 0.1 12.2 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression M11L PF11099.8 EGO25545.1 - 1 9.6 3.5 0.56 10.5 0.2 2.1 2 0 0 2 2 2 0 Apoptosis regulator M11L like FAD_binding_3 PF01494.19 EGO25549.1 - 1.3e-29 103.6 0.0 2.9e-29 102.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO25549.1 - 2.2e-11 43.6 0.2 2e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO25549.1 - 2.6e-05 24.0 0.4 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO25549.1 - 4.1e-05 24.1 0.8 0.05 14.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO25549.1 - 0.0011 17.9 0.3 1.4 7.6 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EGO25549.1 - 0.0045 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EGO25549.1 - 0.0056 15.8 0.0 0.37 9.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.6 EGO25549.1 - 0.03 13.6 1.6 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO25549.1 - 0.094 11.8 0.3 0.26 10.3 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L11_N PF03946.14 EGO25550.1 - 9.8e-24 83.0 0.1 1.5e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGO25550.1 - 6.5e-18 65.0 0.3 1.1e-17 64.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.11 EGO25551.1 - 8.2e-29 101.0 0.3 8.2e-29 101.0 0.3 1.9 2 1 1 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGO25551.1 - 0.00035 20.3 0.2 0.00055 19.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain E1-E2_ATPase PF00122.20 EGO25552.1 - 1.6e-38 132.0 7.8 1.8e-38 131.9 0.2 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 EGO25552.1 - 6.4e-15 56.0 0.3 1.6e-14 54.7 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO25552.1 - 5e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO25552.1 - 0.02 14.6 0.1 0.02 14.6 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO25552.1 - 0.14 12.3 0.1 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Cation transport ATPase (P-type) TRI5 PF06330.11 EGO25553.1 - 4.9e-06 25.6 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) MFS_1 PF07690.16 EGO25560.1 - 3.6e-17 62.3 35.8 3.6e-17 62.3 35.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4928 PF16280.5 EGO25560.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) FBPase_3 PF01950.16 EGO25560.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase DUF1560 PF07597.11 EGO25561.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) WD40 PF00400.32 EGO25562.1 - 5.7e-43 144.1 25.7 6.1e-09 36.4 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO25562.1 - 6e-10 39.3 1.2 0.071 13.4 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO25562.1 - 6.4e-05 21.8 5.2 0.0099 14.6 0.1 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EGO25562.1 - 0.00028 20.1 0.0 0.047 12.8 0.0 2.8 2 2 0 2 2 2 2 Protein of unknown function (DUF1513) PD40 PF07676.12 EGO25562.1 - 0.00039 20.3 2.2 2.9 7.9 0.0 4.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGO25562.1 - 0.0061 15.1 0.0 0.52 8.8 0.1 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EGO25562.1 - 0.01 15.7 0.3 0.65 9.8 0.1 2.8 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO25562.1 - 0.16 11.2 0.1 18 4.6 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain IU_nuc_hydro PF01156.19 EGO25563.1 - 2.4e-39 135.7 0.0 3e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4939 PF16297.5 EGO25566.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) DUF1690 PF07956.11 EGO25566.1 - 0.014 15.8 3.6 0.024 15.1 3.6 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) TipAS PF07739.13 EGO25566.1 - 0.02 15.5 0.4 0.052 14.1 0.4 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF4105 PF13387.6 EGO25566.1 - 0.42 10.2 3.8 5 6.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) Asp_protease_2 PF13650.6 EGO25567.1 - 8.1e-05 23.2 0.1 0.0013 19.4 0.0 2.6 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO25567.1 - 0.00065 20.2 0.2 0.013 16.0 0.0 2.8 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease Ndc1_Nup PF09531.10 EGO25567.1 - 2.7 6.6 4.9 3.3 6.3 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Retrotran_gag_2 PF14223.6 EGO25568.1 - 5.3e-11 42.3 0.2 7.9e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AP3D1 PF06375.11 EGO25568.1 - 0.9 9.8 7.9 1.2 9.3 7.9 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PRCH PF03967.13 EGO25569.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Arginase PF00491.21 EGO25570.1 - 4.6e-88 295.4 0.1 5.8e-88 295.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EGO25570.1 - 0.08 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SBF PF01758.16 EGO25571.1 - 0.00028 20.6 3.2 0.00038 20.2 3.2 1.2 1 0 0 1 1 1 1 Sodium Bile acid symporter family RabGAP-TBC PF00566.18 EGO25572.1 - 6.8e-40 137.0 0.0 9.3e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.20 EGO25573.1 - 1.2e-19 70.2 1.1 3.4e-19 68.8 1.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 EGO25573.1 - 0.018 15.4 0.5 3 8.3 0.1 3.8 2 2 1 3 3 3 0 HEAT repeats Cnd1 PF12717.7 EGO25573.1 - 0.073 13.1 1.5 0.2 11.7 0.1 2.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGO25573.1 - 0.78 10.2 4.1 4.2 7.9 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Ferritin_2 PF13668.6 EGO25577.1 - 1.1e-18 67.8 0.0 1.5e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF5039 PF16442.5 EGO25577.1 - 0.044 13.3 0.1 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) Git3 PF11710.8 EGO25578.1 - 1.1e-09 38.3 12.0 4e-09 36.5 12.0 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGO25578.1 - 0.0096 16.0 0.4 0.0096 16.0 0.4 3.0 4 0 0 4 4 4 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF423 PF04241.15 EGO25578.1 - 0.76 10.0 5.4 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Cellulase PF00150.18 EGO25579.1 - 2.4e-30 105.9 1.1 3.5e-30 105.4 1.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nop25 PF09805.9 EGO25580.1 - 7.4e-22 78.3 22.1 7.4e-22 78.3 22.1 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Nexin_C PF08628.12 EGO25580.1 - 6.1 7.5 9.5 0.28 11.8 2.6 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal V-SNARE_C PF12352.8 EGO25581.1 - 2e-14 53.6 0.2 2e-14 53.6 0.2 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGO25581.1 - 1.7e-05 24.6 0.8 6.2e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 Sec20 She9_MDM33 PF05546.11 EGO25581.1 - 0.0025 17.6 0.6 0.0025 17.6 0.6 1.6 2 0 0 2 2 2 1 She9 / Mdm33 family Plasmid_RAQPRD PF09686.10 EGO25581.1 - 0.019 15.1 2.4 0.24 11.6 1.2 2.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) EMC3_TMCO1 PF01956.16 EGO25581.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SLATT_4 PF18186.1 EGO25581.1 - 0.041 13.5 0.3 0.075 12.7 0.3 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 CLZ PF16526.5 EGO25581.1 - 0.64 10.4 4.2 1.2 9.5 0.8 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HALZ PF02183.18 EGO25581.1 - 0.83 9.9 3.6 1.2 9.4 0.4 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Auto_anti-p27 PF06677.12 EGO25582.1 - 1.8e-26 92.0 6.6 9.4e-14 51.3 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.21 EGO25582.1 - 0.081 13.2 1.1 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Lactamase_B PF00753.27 EGO25584.1 - 1.5e-09 38.1 1.0 2.3e-09 37.6 1.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO25584.1 - 4.8e-07 29.5 0.1 8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Yae1_N PF09811.9 EGO25585.1 - 8.7e-08 31.7 20.2 8.4e-05 22.2 11.5 3.5 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Amidohydro_2 PF04909.14 EGO25585.1 - 0.00031 20.6 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Effector_1 PF04518.12 EGO25585.1 - 0.0024 17.0 4.5 0.0036 16.5 4.5 1.1 1 0 0 1 1 1 1 Effector from type III secretion system RVT_N PF13655.6 EGO25585.1 - 0.043 14.1 1.0 0.13 12.6 1.0 1.8 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase Phage_GP20 PF06810.11 EGO25585.1 - 0.31 10.9 6.0 0.68 9.7 6.0 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 EGO25585.1 - 0.74 7.6 8.3 1 7.2 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 EGO25585.1 - 0.92 8.8 15.1 0.8 9.0 13.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SNase PF00565.17 EGO25586.1 - 1.1e-55 186.7 0.1 6.3e-20 71.7 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGO25586.1 - 4.1e-20 72.0 0.0 7.3e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 EGO25586.1 - 0.025 15.1 0.1 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 Agenet domain Trp_halogenase PF04820.14 EGO25587.1 - 0.072 11.9 0.0 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 EGO25588.1 - 1.4e-12 47.2 36.7 9e-10 38.0 9.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Dermcidin PF15291.6 EGO25590.1 - 0.11 13.0 4.0 2.2 8.9 0.1 2.4 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide SRP-alpha_N PF04086.13 EGO25590.1 - 0.31 10.9 6.5 0.37 10.7 6.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Acetyltransf_1 PF00583.25 EGO25591.1 - 0.00029 21.1 0.0 0.00038 20.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO25591.1 - 0.0038 17.1 0.0 0.0099 15.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO25591.1 - 0.0052 17.2 0.0 0.017 15.5 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO25591.1 - 0.025 14.6 0.0 3.4 7.8 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO25591.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UDPGP PF01704.18 EGO25592.1 - 7.6e-197 653.9 3.3 9.1e-197 653.7 3.3 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Thioredoxin_15 PF18403.1 EGO25592.1 - 0.056 13.4 0.5 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Metallophos PF00149.28 EGO25593.1 - 1.5e-14 55.0 0.2 2.3e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UDPGP PF01704.18 EGO25594.1 - 5.8e-187 621.4 0.6 7e-186 617.8 0.6 1.9 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CsoSCA PF08936.10 EGO25594.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Ribosomal_S8e PF01201.22 EGO25595.1 - 4.4e-56 188.8 1.9 5.9e-56 188.4 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Cpn60_TCP1 PF00118.24 EGO25596.1 - 7.4e-165 549.3 0.2 9.8e-165 548.9 0.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short_C2 PF13561.6 EGO25598.1 - 2.3e-54 184.4 2.2 3.5e-54 183.9 2.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO25598.1 - 1.9e-40 138.4 0.8 2.6e-40 138.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO25598.1 - 5.7e-11 42.7 1.7 4.5e-10 39.7 1.7 2.0 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EGO25598.1 - 0.061 14.0 0.1 0.15 12.8 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain SbcD_C PF12320.8 EGO25598.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain ARPC4 PF05856.12 EGO25603.1 - 3.4e-79 264.3 4.9 3.9e-79 264.1 4.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) GPS2_interact PF15784.5 EGO25603.1 - 0.031 14.7 1.6 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Gelsolin PF00626.22 EGO25605.1 - 4e-09 36.3 0.0 3.6e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 Gelsolin repeat DUF3697 PF12478.8 EGO25606.1 - 0.08 13.1 0.1 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-associated protein 2 Nse4_C PF08743.10 EGO25607.1 - 3.1e-30 104.3 1.1 4.1e-30 103.9 0.1 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGO25607.1 - 2.7e-17 62.6 1.9 6.1e-17 61.5 1.9 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE SNF2_N PF00176.23 EGO25608.1 - 2.2e-65 220.7 0.0 3.3e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EGO25608.1 - 1.4e-21 76.2 0.1 1.1e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 HIRAN domain zf-PARP PF00645.18 EGO25608.1 - 1.2e-17 64.5 0.2 3.6e-17 63.0 0.0 2.0 2 0 0 2 2 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.6 EGO25608.1 - 5.9e-09 35.6 6.8 1.3e-08 34.6 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO25608.1 - 4.9e-08 32.7 7.3 1e-07 31.7 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGO25608.1 - 2.7e-07 30.7 0.1 7.3e-07 29.3 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO25608.1 - 4.1e-07 30.3 0.0 0.0009 19.6 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGO25608.1 - 1.1e-06 28.4 3.3 1.9e-06 27.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO25608.1 - 2.3e-06 27.5 8.7 5.2e-06 26.4 8.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGO25608.1 - 2.6e-06 27.7 6.7 5.4e-06 26.6 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGO25608.1 - 1.5e-05 25.0 7.6 3.6e-05 23.8 7.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGO25608.1 - 1.6e-05 24.7 4.7 3.2e-05 23.8 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGO25608.1 - 0.00065 19.9 4.7 0.0028 17.9 4.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO25608.1 - 0.036 13.9 5.9 0.14 12.1 6.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cue1_U7BR PF18499.1 EGO25608.1 - 0.096 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 zf-RING_6 PF14835.6 EGO25608.1 - 0.39 10.6 2.4 0.87 9.5 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EGO25608.1 - 0.66 10.2 2.8 2 8.6 2.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 Gastrin PF00918.17 EGO25608.1 - 4.1 8.4 6.2 23 6.0 5.3 2.6 2 0 0 2 2 2 0 Gastrin/cholecystokinin family NAD_binding_4 PF07993.12 EGO25609.1 - 4.1e-30 104.8 0.0 6.2e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO25609.1 - 5.3e-22 78.0 0.0 1e-19 70.5 0.0 2.4 3 0 0 3 3 3 2 AMP-binding enzyme Epimerase PF01370.21 EGO25609.1 - 1.5e-07 31.2 0.0 5.1e-07 29.4 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO25609.1 - 0.056 13.8 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 EGO25609.1 - 0.066 13.1 0.0 1.1 9.1 0.0 2.6 2 1 0 2 2 2 0 NAD(P)H-binding CUE PF02845.16 EGO25609.1 - 0.12 12.1 0.3 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 CUE domain KR PF08659.10 EGO25609.1 - 0.14 12.0 0.3 1.1 9.1 0.0 2.6 2 1 0 2 2 2 0 KR domain Ribosomal_S7 PF00177.21 EGO25610.1 - 1.5e-36 125.2 1.8 1.9e-36 124.9 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4587 PF15248.6 EGO25611.1 - 0.0077 17.0 4.2 0.022 15.6 4.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4587) DNA_pol_A_exoN PF18305.1 EGO25611.1 - 0.095 13.0 0.2 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain DUF3533 PF12051.8 EGO25614.1 - 7.9e-79 265.3 10.2 2.1e-76 257.3 10.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3533) UL45 PF05473.12 EGO25614.1 - 0.11 12.2 0.7 0.67 9.6 0.0 2.3 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like zf-RING_2 PF13639.6 EGO25615.1 - 4e-10 39.9 1.9 4.4e-08 33.3 0.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGO25615.1 - 4.7e-09 36.4 1.8 8.4e-08 32.4 0.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGO25615.1 - 1.9e-08 34.0 5.6 7.1e-08 32.2 1.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO25615.1 - 1.4e-06 28.0 0.8 5.8e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO25615.1 - 2.4e-06 27.2 4.6 0.00036 20.2 0.0 3.1 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_UBOX PF13445.6 EGO25615.1 - 1.5e-05 24.9 6.7 0.0014 18.6 0.1 3.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO25615.1 - 3.2e-05 23.8 1.0 7.8e-05 22.6 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO25615.1 - 5.9e-05 22.8 0.9 0.00016 21.5 0.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGO25615.1 - 0.00083 19.4 0.1 0.00083 19.4 0.1 2.4 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGO25615.1 - 0.0034 17.2 1.9 0.007 16.2 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGO25615.1 - 0.024 14.2 0.8 0.024 14.2 0.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGO25615.1 - 0.04 14.1 0.5 0.04 14.1 0.5 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EGO25615.1 - 0.2 12.0 0.6 0.52 10.7 0.6 1.7 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EGO25615.1 - 0.27 11.4 3.4 1.2 9.4 1.6 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain FA_desaturase PF00487.24 EGO25615.1 - 0.33 10.7 6.7 0.036 13.9 2.0 1.7 2 0 0 2 2 2 0 Fatty acid desaturase RINGv PF12906.7 EGO25615.1 - 1.7 8.8 4.2 0.69 10.1 0.9 2.0 2 0 0 2 2 2 0 RING-variant domain ESSS PF10183.9 EGO25615.1 - 6.3 7.1 7.7 15 5.9 0.0 3.3 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HAD_2 PF13419.6 EGO25616.1 - 3.5e-13 50.0 0.0 5.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO25616.1 - 1.5e-09 38.4 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO25616.1 - 4.8e-05 23.3 0.1 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Ribosomal_S6 PF01250.17 EGO25617.1 - 5.9e-22 77.8 0.1 7.8e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 RRM_2 PF04059.12 EGO25620.1 - 9.2e-33 112.3 1.0 1.2e-32 111.9 1.0 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGO25620.1 - 0.0087 15.9 0.1 0.022 14.6 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGO25620.1 - 0.047 13.9 0.1 0.066 13.4 0.1 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 SapB_1 PF05184.15 EGO25620.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 MIF4G PF02854.19 EGO25621.1 - 3e-44 151.2 0.8 1.2e-30 106.8 0.0 3.1 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 EGO25621.1 - 3.1e-30 105.7 3.3 3.1e-30 105.7 3.3 2.9 2 1 1 3 3 3 1 Up-frameshift suppressor 2 AATF-Che1 PF13339.6 EGO25621.1 - 2.5 8.8 6.2 0.91 10.2 0.2 3.3 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor Acetyltransf_1 PF00583.25 EGO25624.1 - 4.1e-11 43.1 0.0 7e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO25624.1 - 3.8e-08 33.3 0.0 6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO25624.1 - 2.4e-07 30.6 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGO25624.1 - 5.7e-05 23.5 0.0 8.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO25624.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RPA43_OB PF17875.1 EGO25625.1 - 1e-25 90.8 4.2 5.3e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EGO25625.1 - 6.3e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DDRGK PF09756.9 EGO25625.1 - 0.0072 15.9 0.3 0.0072 15.9 0.3 1.4 2 0 0 2 2 2 1 DDRGK domain Pam16 PF03656.13 EGO25626.1 - 1.2e-21 77.0 1.0 1.7e-13 50.7 0.0 2.4 2 1 0 2 2 2 2 Pam16 GOLGA2L5 PF15070.6 EGO25627.1 - 0.028 13.1 7.9 0.04 12.6 7.9 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 zf-C4H2 PF10146.9 EGO25627.1 - 0.03 14.6 0.1 0.075 13.3 0.1 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein Spc29 PF17082.5 EGO25627.1 - 0.064 13.1 1.6 0.11 12.3 0.6 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 E3_UbLigase_R4 PF13764.6 EGO25627.1 - 0.16 10.1 0.7 0.25 9.5 0.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Fib_alpha PF08702.10 EGO25627.1 - 0.57 10.4 2.9 6.7 6.9 1.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EGO25627.1 - 1.6 9.2 5.3 12 6.5 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 GAS PF13851.6 EGO25627.1 - 4.9 6.5 8.1 2.6 7.4 5.7 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 EGO25627.1 - 6.6 6.9 16.3 0.45 10.7 9.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF745 PF05335.13 EGO25627.1 - 8.7 6.0 14.5 7.1 6.3 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PPR_2 PF13041.6 EGO25628.1 - 2.4e-35 120.5 0.1 3.8e-07 30.2 0.0 8.9 3 2 7 10 10 10 9 PPR repeat family PPR_3 PF13812.6 EGO25628.1 - 2.4e-28 98.0 0.0 1.5e-05 25.0 0.0 6.0 5 1 2 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 EGO25628.1 - 5e-20 71.8 0.0 3.6e-05 23.2 0.0 4.6 1 1 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGO25628.1 - 3.1e-15 55.3 10.0 0.0052 17.0 0.1 10.4 11 1 0 11 11 11 3 PPR repeat PPR_1 PF12854.7 EGO25628.1 - 1.1e-13 50.6 0.0 0.058 13.1 0.0 7.1 7 0 0 7 7 7 4 PPR repeat Phage_ABA_S PF18066.1 EGO25628.1 - 0.085 13.5 0.1 7.7 7.3 0.0 2.9 2 1 0 2 2 2 0 Phage ABA sandwich domain Rad21_Rec8_N PF04825.13 EGO25629.1 - 1.3e-36 125.2 0.1 2.5e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGO25629.1 - 8.9e-13 47.3 0.0 1.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein NIF PF03031.18 EGO25630.1 - 2.1e-54 183.5 0.0 2.4e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGO25630.1 - 0.0088 16.5 0.1 0.1 13.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PTPLA PF04387.14 EGO25631.1 - 6.4e-55 185.4 9.9 1.2e-54 184.4 9.9 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA HMMR_C PF15908.5 EGO25632.1 - 7.1e-06 26.4 0.7 1.2e-05 25.6 0.7 1.4 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal FadA PF09403.10 EGO25632.1 - 0.00015 22.2 0.6 0.00036 21.0 0.6 1.5 1 0 0 1 1 1 1 Adhesion protein FadA Nse5 PF08691.10 EGO25632.1 - 0.09 11.4 0.8 0.098 11.3 0.8 1.0 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 BRE1 PF08647.11 EGO25632.1 - 0.32 11.1 4.3 0.26 11.4 0.3 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SPATA1_C PF15743.5 EGO25632.1 - 0.45 10.6 5.9 1.8 8.6 5.6 1.9 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus LRR_8 PF13855.6 EGO25634.1 - 1.6e-10 40.6 13.8 7e-08 32.1 7.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGO25634.1 - 1e-09 38.5 9.6 0.00019 21.7 4.5 4.0 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGO25634.1 - 0.0049 16.4 1.6 0.22 11.0 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EGO25634.1 - 0.0086 16.5 7.4 12 6.9 0.2 5.9 6 1 0 6 6 6 1 Leucine Rich Repeat Glyco_hydro_2_N PF02837.18 EGO25634.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain LRR_6 PF13516.6 EGO25634.1 - 0.18 11.9 12.0 6.3 7.1 0.7 4.7 5 0 0 5 5 5 0 Leucine Rich repeat Arf PF00025.21 EGO25635.1 - 1.5e-77 259.0 0.0 1.7e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGO25635.1 - 2.2e-15 56.9 0.1 3.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGO25635.1 - 4.4e-13 49.1 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGO25635.1 - 8e-12 45.0 1.4 1.7e-07 30.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGO25635.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGO25635.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO25635.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGO25635.1 - 0.017 14.4 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PALP PF00291.25 EGO25636.1 - 9.7e-68 228.7 0.1 1.1e-67 228.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Chitin_synth_1 PF01644.17 EGO25638.1 - 1.4e-74 249.5 0.0 2.8e-74 248.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO25638.1 - 3.6e-27 94.1 0.8 1e-26 92.6 0.1 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO25638.1 - 8.4e-26 90.7 2.5 2.3e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO25638.1 - 1.4e-07 31.6 2.2 6.6e-07 29.4 2.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO25638.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-U1 PF06220.12 EGO25639.1 - 2e-10 40.3 1.8 3.2e-10 39.6 1.8 1.3 1 0 0 1 1 1 1 U1 zinc finger Sds3 PF08598.11 EGO25639.1 - 0.0053 16.8 0.0 0.0066 16.5 0.0 1.3 1 1 0 1 1 1 1 Sds3-like Barttin PF15462.6 EGO25639.1 - 0.089 12.6 3.0 3.8 7.2 0.2 2.3 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-TRM13_CCCH PF11722.8 EGO25639.1 - 0.24 11.2 4.1 0.49 10.2 4.1 1.5 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein DUF1179 PF06678.11 EGO25639.1 - 0.78 9.8 4.2 0.3 11.1 0.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1179) MFS_1 PF07690.16 EGO25640.1 - 3.2e-16 59.2 32.7 3.2e-16 59.2 32.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0020 PF01170.18 EGO25641.1 - 0.0002 21.1 0.0 0.00026 20.7 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EGO25641.1 - 0.062 12.5 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase zf-4CXXC_R1 PF10497.9 EGO25642.1 - 1.2e-10 41.5 15.2 9.6e-09 35.4 15.2 2.5 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WHIM1 PF15612.6 EGO25642.1 - 0.011 15.3 0.2 0.33 10.6 0.1 2.4 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 EGO25642.1 - 0.066 13.7 5.9 0.054 14.0 0.7 3.3 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif OGFr_III PF04680.13 EGO25642.1 - 0.086 13.5 0.6 18 6.1 0.3 2.7 2 0 0 2 2 2 0 Opioid growth factor receptor repeat YabA PF06156.13 EGO25642.1 - 3.2 8.4 10.3 2.7 8.7 1.0 3.4 3 1 0 3 3 3 0 Initiation control protein YabA CDC45 PF02724.14 EGO25642.1 - 5.5 5.2 9.0 10 4.3 0.0 2.8 3 0 0 3 3 3 0 CDC45-like protein Tim17 PF02466.19 EGO25643.1 - 3.4e-30 104.7 7.9 4.6e-30 104.2 7.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyrid_ox_like PF16242.5 EGO25644.1 - 4.5e-29 101.0 0.7 6.4e-29 100.5 0.7 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EGO25644.1 - 2e-11 43.9 0.0 3.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rad9 PF04139.13 EGO25645.1 - 2.8e-10 40.1 0.0 4e-10 39.6 0.0 1.2 1 1 0 1 1 1 1 Rad9 NmrA PF05368.13 EGO25646.1 - 2.5e-27 95.9 0.0 3.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO25646.1 - 3.7e-12 46.5 0.0 5.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO25646.1 - 2.1e-05 24.1 0.0 8.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO25646.1 - 0.012 14.8 0.0 0.73 9.0 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO25646.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 EGO25646.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_9 PF13454.6 EGO25647.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGO25647.1 - 0.063 12.5 0.0 4.9 6.3 0.0 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DivIC PF04977.15 EGO25648.1 - 0.024 14.4 0.7 0.032 14.0 0.7 1.4 1 1 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 EGO25648.1 - 0.041 14.1 0.4 0.074 13.3 0.3 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper SlyX PF04102.12 EGO25648.1 - 0.077 13.6 1.3 0.095 13.3 1.3 1.1 1 0 0 1 1 1 0 SlyX DUF5044 PF16447.5 EGO25649.1 - 0.014 15.2 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) 2OG-FeII_Oxy_2 PF13532.6 EGO25651.1 - 3.2e-22 79.7 0.0 3.8e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UN_NPL4 PF11543.8 EGO25651.1 - 0.031 14.8 0.1 0.048 14.2 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ATP-synt_DE_N PF02823.16 EGO25655.1 - 6.5e-18 64.4 0.3 1.2e-17 63.6 0.3 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GCS PF03074.16 EGO25656.1 - 2.1e-174 580.1 0.0 2.7e-174 579.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EGO25656.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) APG6 PF04111.12 EGO25657.1 - 2.1e-71 239.6 0.0 2.5e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EGO25657.1 - 0.0009 19.8 3.4 0.0009 19.8 3.4 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region Peptidase_C14 PF00656.22 EGO25660.1 - 1.9e-12 47.7 0.0 2e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain IMS PF00817.20 EGO25662.1 - 3.2e-45 153.8 0.0 5.6e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGO25662.1 - 2.4e-07 31.5 0.2 8.1e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGO25662.1 - 3.8e-07 30.1 0.0 3.3e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif Rad50_zn_hook PF04423.14 EGO25662.1 - 0.14 12.0 0.7 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif kleA_kleC PF17383.2 EGO25664.1 - 0.02 15.2 0.1 0.035 14.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A CAMSAP_CC1 PF17095.5 EGO25664.1 - 0.083 12.8 0.2 1.5 8.7 0.0 2.2 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin DUF2228 PF10228.9 EGO25664.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) VanZ PF04892.12 EGO25665.1 - 5.7e-06 27.0 7.5 2e-05 25.3 7.5 1.8 1 1 0 1 1 1 1 VanZ like family Polysacc_synt_C PF14667.6 EGO25665.1 - 0.0028 17.7 1.7 0.28 11.2 0.3 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain Virul_fac_BrkB PF03631.15 EGO25665.1 - 0.063 12.9 3.4 0.086 12.4 3.4 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Phage_holin_3_3 PF16083.5 EGO25665.1 - 0.22 11.7 2.0 0.42 10.8 2.0 1.4 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Peptidase_U4 PF03419.13 EGO25665.1 - 0.48 9.7 4.8 0.92 8.7 4.8 1.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA RraA-like PF03737.15 EGO25666.1 - 5.4e-37 127.3 0.1 7.2e-37 126.9 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Ank_2 PF12796.7 EGO25667.1 - 2.4e-11 44.0 0.6 7.2e-11 42.5 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO25667.1 - 3.1e-10 40.0 0.2 1.2e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGO25667.1 - 3.6e-10 39.2 0.1 0.00027 21.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGO25667.1 - 1.1e-09 38.4 0.7 5.1e-07 29.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 EGO25667.1 - 1.6e-09 37.7 0.2 8.9e-09 35.3 0.1 2.4 3 0 0 3 3 3 1 IPT/TIG domain Ank_4 PF13637.6 EGO25667.1 - 2.6e-08 34.2 0.1 3.8e-06 27.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ran_BP1 PF00638.18 EGO25668.1 - 0.0026 18.0 1.1 0.0041 17.4 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain RabGAP-TBC PF00566.18 EGO25669.1 - 2.2e-53 181.1 0.1 2.9e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 EGO25669.1 - 0.023 14.7 0.1 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Interleukin 34 SPX PF03105.19 EGO25669.1 - 0.18 11.7 6.6 0.26 11.2 6.6 1.1 1 0 0 1 1 1 0 SPX domain HicA_toxin PF07927.12 EGO25670.1 - 3.9e-07 30.0 0.6 1.8e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, TFIIA PF03153.13 EGO25670.1 - 1.7 8.6 15.8 1.9 8.4 6.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP_transf PF09830.9 EGO25671.1 - 9.6e-21 73.7 0.0 1.7e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EGO25671.1 - 0.00066 19.5 0.0 0.077 12.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4922) HIT PF01230.23 EGO25671.1 - 0.064 14.0 0.3 0.56 11.0 0.0 2.4 2 0 0 2 2 2 0 HIT domain DUF2613 PF11021.8 EGO25673.1 - 0.17 12.0 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) ILVD_EDD PF00920.21 EGO25674.1 - 1.2e-204 680.8 0.0 1.3e-204 680.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.28 EGO25677.1 - 1.5e-15 56.2 0.1 0.00011 21.8 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25677.1 - 2.7e-14 52.0 3.9 0.001 19.0 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25677.1 - 6.1e-11 42.8 8.4 2.2e-06 28.2 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO25677.1 - 4.9e-09 35.6 0.8 0.096 12.8 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25677.1 - 8e-09 35.0 0.2 0.073 13.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGO25677.1 - 2.9e-08 33.8 4.2 0.0089 16.8 0.0 5.2 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25677.1 - 2.5e-07 30.9 3.0 0.021 15.1 0.2 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO25677.1 - 5e-06 26.9 2.1 0.21 12.1 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25677.1 - 2.7e-05 24.3 0.1 1 9.9 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO25677.1 - 3.9e-05 23.2 3.6 0.0067 16.1 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_10 PF13374.6 EGO25677.1 - 0.00016 21.4 9.0 2.7 8.0 0.1 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGO25677.1 - 0.00055 20.4 4.5 0.2 12.4 0.0 4.7 4 1 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO25677.1 - 0.011 15.9 0.1 0.21 11.8 0.1 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGO25677.1 - 0.02 15.0 1.8 2.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGO25677.1 - 0.035 13.3 0.1 0.088 12.0 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGO25677.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Coatomer epsilon subunit DUF1655 PF07868.11 EGO25681.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) ETF PF01012.21 EGO25685.1 - 1.2e-36 126.3 0.0 1.8e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGO25685.1 - 1.2e-31 108.6 0.4 2.7e-31 107.4 0.4 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pkinase PF00069.25 EGO25686.1 - 4.8e-07 29.4 0.0 7.5e-05 22.2 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25686.1 - 0.025 13.9 0.1 0.18 11.1 0.0 2.2 2 1 0 2 2 2 0 Protein tyrosine kinase Plavaka PF18759.1 EGO25689.1 - 4.5e-45 154.3 7.5 2.7e-23 82.7 0.6 3.1 1 1 1 2 2 2 2 Plavaka transposase FMO-like PF00743.19 EGO25691.1 - 6.2e-18 64.5 0.0 7.1e-16 57.7 0.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO25691.1 - 1.1e-14 54.4 0.0 8e-13 48.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO25691.1 - 2.5e-14 53.2 0.0 8.7e-09 35.0 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGO25691.1 - 6.1e-13 48.7 0.0 0.00012 21.5 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO25691.1 - 5.1e-06 27.0 0.0 0.00083 19.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO25691.1 - 0.00012 22.3 0.0 0.00047 20.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO25691.1 - 0.0019 17.8 0.0 1.5 8.3 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO25691.1 - 0.0023 16.7 0.0 0.01 14.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGO25691.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO25691.1 - 0.081 12.0 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO25691.1 - 0.092 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 EGO25691.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EGO25691.1 - 0.19 11.1 0.0 0.48 9.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 EGO25693.1 - 8.5e-08 31.9 0.0 1.4e-05 24.6 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25693.1 - 0.11 11.7 0.0 0.53 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Retrotran_gag_2 PF14223.6 EGO25695.1 - 2.8e-09 36.8 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGO25695.1 - 2.6e-05 24.0 0.0 6.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO25695.1 - 6.6e-05 22.5 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Pkinase PF00069.25 EGO25699.1 - 1.2e-07 31.4 0.0 1.5e-05 24.5 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25699.1 - 0.015 14.6 0.0 0.1 11.8 0.0 2.2 2 1 1 3 3 3 0 Protein tyrosine kinase TetR_C_2 PF08361.11 EGO25700.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Pkinase PF00069.25 EGO25701.1 - 5.9e-08 32.4 0.0 9.6e-06 25.1 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25701.1 - 0.073 12.4 0.0 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase RC-P840_PscD PF10657.9 EGO25702.1 - 0.11 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD RbsD_FucU PF05025.13 EGO25703.1 - 0.011 16.1 0.5 0.02 15.3 0.5 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family MFS_1 PF07690.16 EGO25705.1 - 1.4e-35 122.9 55.6 1.6e-35 122.6 51.2 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO25705.1 - 7.9e-24 84.0 14.3 1.1e-23 83.5 14.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO25705.1 - 2.4e-14 53.0 10.1 2.4e-14 53.0 10.1 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter FMO-like PF00743.19 EGO25706.1 - 7.2e-22 77.5 0.0 2.7e-20 72.3 0.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO25706.1 - 6e-15 55.3 0.0 4e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO25706.1 - 6.1e-15 55.2 0.1 1.8e-11 43.8 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO25706.1 - 5.7e-13 48.7 0.0 2.3e-07 30.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGO25706.1 - 8.1e-06 26.3 0.0 0.0016 19.0 0.1 3.0 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO25706.1 - 1.8e-05 24.5 0.0 0.12 12.0 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO25706.1 - 2.8e-05 24.3 0.0 0.00011 22.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO25706.1 - 0.0016 17.2 0.0 0.0074 15.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EGO25706.1 - 0.005 16.8 0.2 2.7 8.0 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGO25706.1 - 0.014 14.5 0.1 0.091 11.8 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 EGO25706.1 - 0.021 13.9 0.0 0.08 12.0 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EGO25706.1 - 0.024 14.0 0.0 0.068 12.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EGO25706.1 - 0.036 13.2 0.1 0.069 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EGO25706.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGO25706.1 - 0.082 12.1 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 EGO25707.1 - 1.1e-16 60.4 0.1 1.1e-14 53.7 0.1 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO25707.1 - 2.8e-14 53.1 0.0 3.3e-12 46.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO25707.1 - 7.2e-14 51.7 0.0 0.00011 21.5 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO25707.1 - 4.6e-13 49.0 0.0 8.8e-08 31.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGO25707.1 - 8e-06 26.3 0.0 0.00083 19.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO25707.1 - 0.0001 22.5 0.0 0.00047 20.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO25707.1 - 0.003 16.3 0.0 0.01 14.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EGO25707.1 - 0.015 14.4 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGO25707.1 - 0.031 13.9 0.0 1.4 8.4 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO25707.1 - 0.052 13.5 0.0 34 4.4 0.0 3.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EGO25707.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EGO25707.1 - 0.1 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EGO25707.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EGO25707.1 - 0.13 11.3 0.1 0.9 8.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A GHMP_kinases_C PF08544.13 EGO25707.1 - 0.14 12.5 0.0 9.9 6.6 0.0 2.6 1 1 1 2 2 2 0 GHMP kinases C terminal TrkA_N PF02254.18 EGO25707.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain zf-trcl PF13451.6 EGO25710.1 - 0.6 10.0 5.9 0.4 10.6 4.7 1.4 1 1 0 1 1 1 0 Probable zinc-ribbon domain Retrotrans_gag PF03732.17 EGO25711.1 - 4.2e-06 26.9 2.1 4.2e-06 26.9 2.1 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO25711.1 - 0.00051 20.0 1.8 0.00086 19.3 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO25712.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3289 PF11692.8 EGO25712.1 - 0.055 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) DUF4939 PF16297.5 EGO25712.1 - 0.064 13.1 0.0 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4939) zf-C2H2_jaz PF12171.8 EGO25716.1 - 1.7e-10 40.9 6.1 7.7e-08 32.4 1.1 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO25716.1 - 6.6e-08 32.7 1.4 6.6e-08 32.7 1.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGO25716.1 - 8.8e-05 22.8 3.8 0.0033 17.7 4.1 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGO25716.1 - 0.00059 20.1 6.7 0.003 17.9 0.6 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO25716.1 - 0.0011 19.6 4.6 0.11 13.4 0.1 2.6 3 0 0 3 3 2 2 C2H2-type zinc finger DUF4674 PF15719.5 EGO25716.1 - 0.02 14.9 1.6 0.02 14.9 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) DUF629 PF04780.12 EGO25716.1 - 0.037 12.6 0.4 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-DBF PF07535.12 EGO25716.1 - 0.062 13.4 0.4 0.062 13.4 0.4 2.2 2 0 0 2 2 2 0 DBF zinc finger AKAP95 PF04988.12 EGO25716.1 - 0.13 12.5 1.6 0.55 10.5 0.2 1.9 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-LYAR PF08790.11 EGO25716.1 - 0.19 11.6 3.0 9.5 6.2 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Rpr2 PF04032.16 EGO25716.1 - 1.1 9.6 4.3 0.66 10.3 1.1 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.6 EGO25716.1 - 6.8 7.3 9.4 21 5.8 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger double domain DUF1279 PF06916.13 EGO25719.1 - 5.8e-18 65.2 0.0 7.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) CARMIL_C PF16000.5 EGO25719.1 - 0.096 12.3 2.1 0.14 11.8 2.1 1.1 1 0 0 1 1 1 0 CARMIL C-terminus HAMP PF00672.25 EGO25719.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 HAMP domain SAM_decarbox PF01536.16 EGO25720.1 - 4.7e-121 404.1 0.0 7.7e-121 403.4 0.0 1.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PP2C PF00481.21 EGO25722.1 - 1.9e-26 93.2 0.0 5.4e-25 88.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGO25722.1 - 7e-05 22.6 0.0 0.00018 21.3 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGO25722.1 - 0.0045 16.9 0.1 0.28 11.1 0.0 2.7 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Zn_clus PF00172.18 EGO25723.1 - 8.6e-07 29.0 22.5 8.6e-05 22.6 13.8 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EGO25723.1 - 3.4 8.1 16.2 1 9.7 1.6 2.9 2 1 1 3 3 3 0 Opy2 protein Dfp1_Him1_M PF08630.10 EGO25725.1 - 2.2e-32 112.0 0.0 9.2e-32 109.9 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EGO25725.1 - 4.6e-19 68.3 0.2 9.4e-19 67.3 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EGO25725.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGO25725.1 - 0.025 14.5 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain HK97-gp10_like PF04883.12 EGO25725.1 - 0.083 13.9 3.4 0.26 12.3 3.4 1.8 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component ZapA PF05164.13 EGO25725.1 - 0.13 12.7 1.0 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapA Spt5_N PF11942.8 EGO25725.1 - 5.1 8.2 10.3 4.3 8.4 0.3 3.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GCP_C_terminal PF04130.13 EGO25726.1 - 1.1e-62 212.3 0.2 1.1e-62 212.3 0.2 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGO25726.1 - 1.6e-06 27.9 2.2 2.2e-06 27.5 0.2 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal TP6A_N PF04406.14 EGO25729.1 - 1.2e-21 76.4 0.0 2.1e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase F-box-like PF12937.7 EGO25730.1 - 0.012 15.5 0.7 3.9 7.5 0.0 2.8 3 0 0 3 3 3 0 F-box-like RyR PF02026.16 EGO25730.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 RyR domain Ctr PF04145.15 EGO25731.1 - 1.7e-36 126.0 0.2 2e-36 125.8 0.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family 2TM PF13239.6 EGO25731.1 - 8.1 6.8 8.1 0.61 10.4 0.2 2.1 2 0 0 2 2 2 0 2TM domain Proteasome PF00227.26 EGO25732.1 - 6.9e-54 182.2 0.0 9.9e-54 181.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO25732.1 - 1.6e-13 50.1 0.1 2.9e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SKI PF01202.22 EGO25733.1 - 2.9e-09 37.2 0.0 1.9e-07 31.3 0.0 2.5 2 1 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 EGO25733.1 - 4e-08 33.9 0.0 3.1e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO25733.1 - 3.4e-05 24.0 0.0 0.00013 22.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO25733.1 - 0.006 16.9 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGO25733.1 - 0.0094 16.5 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGO25733.1 - 0.021 15.2 0.0 0.033 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain dNK PF01712.19 EGO25733.1 - 0.028 14.3 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 EGO25733.1 - 0.034 14.3 0.0 0.077 13.1 0.0 1.6 2 0 0 2 2 1 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 EGO25733.1 - 0.041 13.6 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 EGO25733.1 - 0.042 13.6 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGO25733.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO25733.1 - 0.048 13.9 0.2 0.085 13.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO25733.1 - 0.059 13.3 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase APS_kinase PF01583.20 EGO25733.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EGO25733.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGO25733.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 EGO25733.1 - 0.19 11.6 0.2 0.98 9.2 0.0 2.2 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein FMO-like PF00743.19 EGO25735.1 - 2.9e-22 78.8 0.4 7.1e-18 64.3 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO25735.1 - 4e-16 59.1 0.0 1.7e-14 53.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO25735.1 - 2.2e-15 56.7 0.0 1.6e-06 27.5 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO25735.1 - 3.1e-13 49.6 0.0 1.8e-07 30.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGO25735.1 - 4e-07 30.5 0.1 0.00026 21.5 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO25735.1 - 8.8e-05 22.7 0.0 0.00036 20.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO25735.1 - 0.00011 22.0 0.3 0.34 10.5 0.4 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO25735.1 - 0.003 17.5 0.2 0.62 10.0 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGO25735.1 - 0.0061 15.3 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EGO25735.1 - 0.0095 15.0 0.0 0.074 12.1 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EGO25735.1 - 0.019 14.3 0.0 0.05 13.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EGO25735.1 - 0.039 13.0 0.1 0.16 11.0 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGO25735.1 - 0.041 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EGO25735.1 - 0.061 12.4 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGO25735.1 - 0.16 11.2 0.0 0.4 9.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family TatD_DNase PF01026.21 EGO25736.1 - 1.7e-51 175.0 0.0 2.2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase NPCBM PF08305.11 EGO25737.1 - 0.14 12.4 0.1 0.36 11.0 0.1 1.7 1 1 1 2 2 2 0 NPCBM/NEW2 domain Nuc_rec_co-act PF08815.10 EGO25737.1 - 0.14 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator MFS_1 PF07690.16 EGO25739.1 - 1.7e-16 60.1 35.9 2.8e-16 59.4 35.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO25739.1 - 3.6e-14 52.8 6.6 3.6e-14 52.8 6.6 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Methyltransf_25 PF13649.6 EGO25741.1 - 2.5e-14 53.7 0.0 6.5e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO25741.1 - 1.2e-13 51.1 0.1 2.1e-13 50.3 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGO25741.1 - 8.6e-12 45.1 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGO25741.1 - 4.4e-11 43.3 0.0 1.1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO25741.1 - 1e-08 35.2 0.0 5.1e-08 32.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGO25741.1 - 8.5e-08 31.5 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EGO25741.1 - 1.8e-07 31.8 0.0 3.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO25741.1 - 7.6e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGO25741.1 - 6.1e-06 25.9 0.1 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGO25741.1 - 4.6e-05 22.9 0.5 0.00012 21.5 0.2 1.9 2 1 0 2 2 2 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 EGO25741.1 - 5.5e-05 22.6 0.0 9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EGO25741.1 - 0.00031 20.7 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO25741.1 - 0.00042 20.1 0.1 0.00067 19.5 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGO25741.1 - 0.0005 20.1 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGO25741.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGO25741.1 - 0.0024 17.6 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 EGO25741.1 - 0.0032 18.5 0.0 0.0071 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGO25741.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2367 PF10164.9 EGO25743.1 - 2.5e-07 31.1 4.5 5.9e-07 29.9 4.5 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) PepSY_TM PF03929.16 EGO25743.1 - 0.046 13.4 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region GCP5-Mod21 PF14609.6 EGO25744.1 - 0.52 8.6 3.1 0.63 8.3 3.1 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 4HB_MCP_1 PF12729.7 EGO25746.1 - 0.034 13.7 0.4 0.043 13.4 0.4 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PrmA PF06325.13 EGO25747.1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PAC2 PF09754.9 EGO25749.1 - 2.4e-23 83.3 0.1 2.7e-23 83.1 0.1 1.0 1 0 0 1 1 1 1 PAC2 family NUC173 PF08161.12 EGO25750.1 - 5.4e-60 202.6 0.2 9.6e-57 191.9 0.3 2.8 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.22 EGO25750.1 - 1.1e-05 25.3 0.3 0.16 12.3 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EGO25750.1 - 0.0023 18.4 0.5 1.3e+02 3.3 0.1 6.0 5 0 0 5 5 5 0 HEAT-like repeat Aminotran_5 PF00266.19 EGO25750.1 - 0.024 13.6 0.3 0.055 12.4 0.1 1.6 2 0 0 2 2 2 0 Aminotransferase class-V HEAT_2 PF13646.6 EGO25750.1 - 0.24 11.8 2.7 14 6.2 0.0 4.3 5 0 0 5 5 5 0 HEAT repeats Acyltransferase PF01553.21 EGO25751.1 - 3.4e-14 52.6 0.0 1.1e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase ABC2_membrane PF01061.24 EGO25751.1 - 0.25 10.7 10.0 0.95 8.8 5.3 2.2 2 0 0 2 2 2 0 ABC-2 type transporter FAD_binding_3 PF01494.19 EGO25753.1 - 8.5e-16 58.1 0.0 1.4e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EGO25753.1 - 0.12 11.4 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Choline_transpo PF04515.12 EGO25754.1 - 4.1e-81 272.7 14.4 4.1e-81 272.7 14.4 2.1 2 1 0 2 2 2 1 Plasma-membrane choline transporter PP2C PF00481.21 EGO25755.1 - 4e-63 213.5 5.9 1.6e-50 172.1 0.3 2.8 1 1 2 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 EGO25755.1 - 0.00028 20.8 0.4 0.0013 18.7 0.4 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) W2 PF02020.18 EGO25756.1 - 4.5e-13 49.1 0.0 1.2e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon TetR PF13972.6 EGO25756.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor Zn_clus PF00172.18 EGO25757.1 - 7.8e-08 32.3 12.3 1.5e-07 31.4 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO25757.1 - 9.4e-07 28.1 0.1 1.7e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.19 EGO25759.1 - 1.2e-217 723.8 0.0 1.7e-217 723.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGO25759.1 - 8.6e-18 64.2 0.1 2.4e-17 62.8 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGO25759.1 - 2.1e-12 47.6 9.1 5.9e-12 46.2 9.1 1.8 1 0 0 1 1 1 1 DHHA1 domain RPW8 PF05659.11 EGO25759.1 - 0.04 13.6 0.4 2.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Ribosomal_L34 PF00468.17 EGO25760.1 - 6.9e-17 61.2 11.9 9.9e-17 60.6 11.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Ribosomal_S13 PF00416.22 EGO25761.1 - 2.5e-55 186.3 2.4 2.9e-55 186.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EGO25761.1 - 0.02 13.7 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 EGO25761.1 - 0.041 14.3 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) CH PF00307.31 EGO25761.1 - 0.096 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain CBFB_NFYA PF02045.15 EGO25763.1 - 7.3e-29 100.2 7.0 8.4e-29 100.0 7.0 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Tho1_MOS11_C PF18592.1 EGO25764.1 - 4.6e-07 29.5 3.3 0.09 12.6 0.5 3.3 3 0 0 3 3 3 3 Tho1/MOS11 C-terminal domain HeH PF12949.7 EGO25764.1 - 3.2e-05 23.5 0.7 3.2e-05 23.5 0.7 2.0 2 0 0 2 2 2 1 HeH/LEM domain Rho_N PF07498.12 EGO25764.1 - 0.00054 19.8 0.2 0.0011 18.8 0.2 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 EGO25764.1 - 0.11 12.2 0.3 0.88 9.4 0.3 2.4 1 1 0 1 1 1 0 SAP domain peroxidase PF00141.23 EGO25767.1 - 1.6e-44 152.3 0.0 2.6e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Muskelin_N PF06588.11 EGO25768.1 - 2.1e-59 200.8 0.0 3.4e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 EGO25768.1 - 3.5e-28 97.3 3.1 6.3e-11 42.3 0.0 6.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGO25768.1 - 2.8e-27 94.5 4.0 2.4e-09 37.1 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO25768.1 - 5.6e-25 86.8 5.8 2.2e-08 33.9 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGO25768.1 - 7.7e-20 70.4 6.7 1.3e-06 28.5 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EGO25768.1 - 4.3e-16 58.2 6.8 2.4e-08 33.4 0.3 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGO25768.1 - 3.9e-07 29.8 9.0 0.00014 21.7 0.3 5.1 5 1 0 5 5 5 2 Kelch motif Sad1_UNC PF07738.13 EGO25768.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Prefoldin_2 PF01920.20 EGO25769.1 - 6.1e-20 71.1 7.7 7.9e-20 70.8 7.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit V_ATPase_I PF01496.19 EGO25769.1 - 0.67 7.8 5.9 0.73 7.7 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 EGO25769.1 - 0.69 10.0 7.8 4.3 7.4 7.8 2.2 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FapA PF03961.13 EGO25769.1 - 1.6 7.2 4.8 1.8 7.1 4.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A PCRF PF03462.18 EGO25769.1 - 2.4 8.0 9.7 3.4 7.5 9.7 1.3 1 1 0 1 1 1 0 PCRF domain Viral_P18 PF04521.13 EGO25769.1 - 2.7 7.8 6.5 1.4 8.7 0.6 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Spc24 PF08286.11 EGO25769.1 - 4 7.7 10.7 1.1e+02 3.1 10.0 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Pyridoxal_deC PF00282.19 EGO25770.1 - 1.5e-14 53.6 0.0 3.6e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGO25770.1 - 7.9e-09 34.9 0.0 1.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO25770.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_N PF00339.29 EGO25773.1 - 1.1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EGO25773.1 - 1.6e-05 24.7 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4218 PF13960.6 EGO25774.1 - 0.0079 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ATP-synt_DE PF00401.20 EGO25778.1 - 0.026 14.8 1.1 0.049 13.9 1.1 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain EF-hand_4 PF12763.7 EGO25780.1 - 1.1e-13 51.0 0.0 1.1e-08 35.0 0.0 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 EGO25781.1 - 1.1e-16 60.9 1.7 2.6e-08 34.4 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO25781.1 - 2.6e-08 34.0 0.2 1e-05 25.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 EGO25781.1 - 0.012 15.9 2.0 0.061 13.7 1.8 2.2 2 0 0 2 2 2 0 Ring finger domain HOOK PF05622.12 EGO25781.1 - 0.014 13.6 4.9 0.018 13.2 4.9 1.1 1 0 0 1 1 1 0 HOOK protein zf-C3HC4_2 PF13923.6 EGO25781.1 - 0.014 15.2 1.3 0.014 15.2 1.3 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Ge1_WD40 PF16529.5 EGO25781.1 - 0.025 13.6 0.0 0.056 12.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1272 PF06906.11 EGO25781.1 - 0.032 14.3 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 EGO25781.1 - 0.057 13.3 3.3 0.16 11.8 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fmp27_WPPW PF10359.9 EGO25781.1 - 0.073 11.9 3.4 0.1 11.5 3.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-RING_10 PF16685.5 EGO25781.1 - 0.079 13.1 0.4 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Beta_helix_2 PF18835.1 EGO25781.1 - 0.094 12.5 0.8 6.9 6.5 0.0 2.9 1 1 1 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-RING_5 PF14634.6 EGO25781.1 - 0.11 12.5 3.7 0.48 10.4 3.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 EGO25781.1 - 0.12 11.8 0.6 0.29 10.6 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain APG6_N PF17675.1 EGO25781.1 - 0.29 11.6 5.6 0.43 11.1 5.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 EGO25781.1 - 0.3 10.7 5.5 0.47 10.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spectrin PF00435.21 EGO25781.1 - 0.51 10.8 4.8 0.92 10.0 4.8 1.3 1 0 0 1 1 1 0 Spectrin repeat TackOD1 PF18551.1 EGO25781.1 - 3.1 7.4 5.5 0.24 11.0 0.1 1.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 WD40 PF00400.32 EGO25782.1 - 1.9e-11 44.3 5.4 1.6e-08 35.1 0.2 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO25782.1 - 6e-09 36.1 0.0 0.00095 19.4 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGO25782.1 - 0.031 13.2 0.1 0.071 12.0 0.0 1.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 EGO25782.1 - 0.085 12.2 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal SKG6 PF08693.10 EGO25783.1 - 0.18 11.3 6.1 0.44 10.0 6.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4519 PF15012.6 EGO25783.1 - 2.6 8.3 3.8 4.9 7.4 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Phage_Gp15 PF06854.11 EGO25784.1 - 0.058 13.4 0.1 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage Gp15 protein Exo_endo_phos PF03372.23 EGO25788.1 - 6.1e-18 65.2 0.6 2.2e-16 60.1 0.6 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EGO25788.1 - 1.1e-17 63.5 21.5 5e-09 35.8 2.2 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGO25788.1 - 2.1e-11 43.8 6.8 9.1e-06 25.9 1.9 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO25788.1 - 0.0053 17.1 4.0 3.5 8.5 0.4 4.9 3 1 1 4 4 4 1 Leucine Rich Repeat SCIMP PF15050.6 EGO25788.1 - 0.12 12.8 0.2 0.32 11.4 0.2 1.6 1 0 0 1 1 1 0 SCIMP protein Herpes_BLLF1 PF05109.13 EGO25788.1 - 1 7.2 14.1 1.5 6.7 14.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) LRR_6 PF13516.6 EGO25788.1 - 2.2 8.6 10.8 2.5 8.4 0.6 3.4 4 0 0 4 4 4 0 Leucine Rich repeat MDD_C PF18376.1 EGO25789.1 - 1.6e-71 240.0 0.0 2.1e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGO25789.1 - 1.1e-06 28.8 3.8 2.2e-06 27.8 3.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain F-box-like PF12937.7 EGO25790.1 - 1.2e-06 28.3 0.4 5e-06 26.3 0.4 2.1 1 1 0 1 1 1 1 F-box-like COG5 PF10392.9 EGO25791.1 - 0.038 14.2 0.5 0.052 13.7 0.5 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Pkinase PF00069.25 EGO25792.1 - 1.1e-37 129.8 0.0 1.7e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25792.1 - 3.4e-35 121.6 0.0 6.3e-35 120.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO25792.1 - 0.0095 15.9 0.1 0.045 13.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3844 PF12955.7 EGO25794.1 - 1e-30 106.0 4.3 1.7e-30 105.2 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGO25794.1 - 1.7 9.1 10.3 3.6 8.1 10.3 1.5 1 0 0 1 1 1 0 EGF-like domain DUF4690 PF15756.5 EGO25795.1 - 0.0057 17.2 0.1 0.016 15.8 0.1 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Amnionless PF14828.6 EGO25795.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless TNFR_16_TM PF18422.1 EGO25795.1 - 6.5 6.8 5.7 0.94 9.5 0.6 2.0 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Trypan_PARP PF05887.11 EGO25798.1 - 0.0022 17.9 0.8 0.0047 16.9 0.8 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TMEM154 PF15102.6 EGO25798.1 - 0.09 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family I-set PF07679.16 EGO25798.1 - 0.13 12.3 0.0 8.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin I-set domain PT PF04886.12 EGO25798.1 - 0.99 9.0 29.1 0.12 12.0 23.1 2.5 2 0 0 2 2 2 0 PT repeat Lipocalin_4 PF13648.6 EGO25798.1 - 2.3 9.2 13.5 4.3 8.4 1.1 2.6 2 0 0 2 2 2 0 Lipocalin-like domain Flocculin PF00624.18 EGO25798.1 - 7.8 6.8 11.3 4.2 7.7 6.2 2.7 2 0 0 2 2 2 0 Flocculin repeat Mito_carr PF00153.27 EGO25800.1 - 3.5e-71 235.2 6.6 4.2e-25 87.5 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO25800.1 - 0.0024 17.1 0.8 1.5 7.9 0.0 3.2 2 1 1 3 3 3 2 Gammaproteobacterial serine protease DUF3813 PF12758.7 EGO25800.1 - 0.21 12.0 1.0 0.39 11.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Glyco_hydro_63 PF03200.16 EGO25801.1 - 6.1e-07 28.6 12.8 2.7e-06 26.4 1.0 4.2 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain BRCT_2 PF16589.5 EGO25802.1 - 4.8e-10 39.7 0.0 1.5e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGO25802.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PhyH PF05721.13 EGO25804.1 - 4e-44 151.4 0.0 7.1e-44 150.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EGO25804.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase HK PF02110.15 EGO25805.1 - 8.9e-76 254.5 1.2 2.1e-69 233.7 1.4 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EGO25805.1 - 3e-54 183.1 0.1 6.4e-54 182.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase p450 PF00067.22 EGO25806.1 - 1.1e-60 205.7 0.0 1.4e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_Gp23 PF10669.9 EGO25810.1 - 0.14 12.5 4.1 1.8 8.9 0.1 2.8 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) DUF2231 PF09990.9 EGO25810.1 - 0.15 12.5 4.1 5.9 7.4 1.6 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) DUF1772 PF08592.11 EGO25810.1 - 3.4 8.0 11.3 5.1 7.4 7.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) ADH_zinc_N PF00107.26 EGO25811.1 - 3e-22 79.0 0.3 5.8e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO25811.1 - 1.1e-17 63.9 0.0 2.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGO25811.1 - 1.9e-10 41.9 0.0 3.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EGO25811.1 - 1.7e-06 28.1 0.3 0.0015 18.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2855) TrkA_N PF02254.18 EGO25811.1 - 0.044 14.0 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain SUR7 PF06687.12 EGO25812.1 - 3.9e-13 49.5 10.7 1.3e-12 47.8 10.7 1.7 1 1 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EGO25812.1 - 0.003 17.4 5.1 0.0048 16.7 5.1 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein Clc-like PF07062.12 EGO25812.1 - 0.16 11.4 9.1 0.061 12.8 5.6 2.0 1 1 0 1 1 1 0 Clc-like DUF747 PF05346.11 EGO25815.1 - 4.5e-115 384.5 8.0 5.6e-115 384.2 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family F-box-like PF12937.7 EGO25817.1 - 4.8e-05 23.2 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGO25817.1 - 0.00047 20.0 0.5 0.001 19.0 0.1 1.8 2 0 0 2 2 2 1 F-box F-box PF00646.33 EGO25817.1 - 0.036 14.0 1.4 0.75 9.7 0.0 2.8 3 0 0 3 3 3 0 F-box domain baeRF_family8 PF18851.1 EGO25817.1 - 0.11 12.6 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 p450 PF00067.22 EGO25818.1 - 1.2e-32 113.3 0.0 6.2e-32 110.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EGO25819.1 - 1.3e-16 60.8 0.0 2.6e-16 59.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO25819.1 - 3.3e-11 43.0 0.0 5.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO25819.1 - 1.3e-06 29.5 0.0 5.3e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase CI-B14_5a PF07347.12 EGO25820.1 - 0.0091 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) MPDZ_u10 PF16667.5 EGO25820.1 - 0.44 11.5 3.9 0.58 11.1 0.6 2.4 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein G_glu_transpept PF01019.21 EGO25824.1 - 0.16 10.7 1.3 0.19 10.4 1.3 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 EGO25825.1 - 1.6e-139 466.0 0.0 1.8e-139 465.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Rimk_N PF18030.1 EGO25825.1 - 0.049 14.0 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 RimK PreATP-grasp domain DUF2110 PF09883.9 EGO25825.1 - 0.11 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Peptidase_A22B PF04258.13 EGO25826.1 - 2.9e-76 256.7 0.4 3.9e-76 256.3 0.4 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EGO25826.1 - 2e-05 24.2 4.2 7.8e-05 22.3 4.1 2.0 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Sec7 PF01369.20 EGO25829.1 - 1.3e-29 103.2 0.2 2.3e-29 102.4 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGO25829.1 - 6.8e-27 94.2 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain GATA PF00320.27 EGO25829.1 - 5.2e-18 64.4 2.7 1.2e-17 63.2 2.7 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EGO25829.1 - 2.7e-11 43.1 1.4 8e-11 41.6 1.4 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PH PF00169.29 EGO25829.1 - 0.0069 16.9 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 PH domain Glyco_hydro_76 PF03663.14 EGO25830.1 - 6.1e-39 134.6 28.8 8e-39 134.2 28.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CPSF73-100_C PF11718.8 EGO25832.1 - 4.3e-67 225.8 0.1 6.2e-67 225.3 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGO25832.1 - 2.2e-29 102.0 0.0 6.4e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EGO25832.1 - 3e-19 69.2 0.0 6.7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO25832.1 - 1.1e-18 67.9 0.6 7.4e-18 65.3 0.4 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EGO25832.1 - 3.8e-16 58.8 0.1 8.3e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 EGO25832.1 - 2.1e-07 31.0 0.4 4.9e-06 26.5 0.0 2.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EGO25832.1 - 1.1e-06 28.3 2.3 1.5e-06 27.8 0.2 2.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Retrotrans_gag PF03732.17 EGO25833.1 - 0.019 15.2 0.1 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1823 PF08853.11 EGO25833.1 - 0.088 13.0 0.7 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) Peptidase_M60_C PF18630.1 EGO25833.1 - 0.095 12.8 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain DUF4939 PF16297.5 EGO25833.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) Rnk_N PF14760.6 EGO25838.1 - 0.12 12.9 0.6 8.4 7.0 0.4 2.4 2 0 0 2 2 2 0 Rnk N-terminus Mcl1_mid PF12341.8 EGO25840.1 - 1.1e-16 61.0 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region Tn7_Tnp_TnsA_C PF08721.11 EGO25840.1 - 0.041 14.5 0.1 0.094 13.4 0.1 1.6 2 0 0 2 2 2 0 TnsA endonuclease C terminal RrnaAD PF00398.20 EGO25841.1 - 1.2e-21 76.9 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.26 EGO25842.1 - 5.3e-13 49.1 0.0 1e-12 48.1 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO25842.1 - 6.4e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO25842.1 - 0.0037 18.3 0.0 0.0092 17.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO25844.1 - 6.7e-13 48.8 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO25844.1 - 2e-11 43.7 0.0 3.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO25844.1 - 0.062 14.4 0.0 0.11 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Plavaka PF18759.1 EGO25846.1 - 2.4e-81 273.5 0.6 3.2e-80 269.8 0.6 2.1 1 1 0 1 1 1 1 Plavaka transposase zf-met PF12874.7 EGO25846.1 - 0.079 13.4 0.5 0.22 12.0 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ADH_zinc_N PF00107.26 EGO25849.1 - 2.9e-10 40.2 0.0 6.8e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO25849.1 - 1.9e-07 31.0 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO25849.1 - 0.0023 19.0 0.0 0.0038 18.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase OmdA PF13376.6 EGO25849.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated ADH_N PF08240.12 EGO25851.1 - 1.4e-11 44.2 0.1 3.8e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO25851.1 - 4.2e-11 42.9 0.0 8.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO25851.1 - 0.15 13.1 0.0 0.23 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.22 EGO25852.1 - 5.4e-12 45.4 0.1 5.2e-05 23.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO25852.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif PI3_PI4_kinase PF00454.27 EGO25853.1 - 8.8e-35 120.7 0.0 1.9e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pneumo_M2 PF07380.11 EGO25853.1 - 0.12 12.7 0.4 0.35 11.2 0.4 1.8 1 0 0 1 1 1 0 Pneumovirus M2 protein SLAC1 PF03595.17 EGO25854.1 - 2.3e-72 244.0 53.3 2.7e-72 243.8 53.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 EGO25855.1 - 3.4e-77 259.9 46.8 3.9e-77 259.7 46.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CPP1-like PF11833.8 EGO25855.1 - 4.8 6.8 10.1 0.57 9.8 5.3 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Inhibitor_I9 PF05922.16 EGO25858.1 - 0.0013 19.4 0.0 0.0033 18.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Nanovirus_C8 PF05629.11 EGO25858.1 - 0.18 11.9 0.0 0.2 11.7 0.0 1.0 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein HhH-GPD PF00730.25 EGO25859.1 - 1.5e-08 35.0 0.0 2.3e-07 31.2 0.0 2.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3391 PF11871.8 EGO25859.1 - 0.086 13.4 1.2 0.54 10.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Pkinase PF00069.25 EGO25860.1 - 2.2e-37 128.8 0.0 2.6e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25860.1 - 1.2e-14 54.2 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO25860.1 - 7.6e-05 22.2 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO25860.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO25860.1 - 0.0064 15.9 0.2 0.009 15.4 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO25860.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGO25860.1 - 0.16 10.7 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Oxidored_q6 PF01058.22 EGO25861.1 - 2.1e-22 79.3 0.1 3.3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mnd1 PF03962.15 EGO25863.1 - 2.7e-31 107.6 0.1 6.5e-31 106.4 0.2 1.6 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGO25863.1 - 1e-07 31.9 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FUR PF01475.19 EGO25863.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Ferric uptake regulator family Penicillinase_R PF03965.16 EGO25863.1 - 0.015 15.6 0.0 0.07 13.5 0.0 2.1 2 1 0 2 2 2 0 Penicillinase repressor TrmB PF01978.19 EGO25863.1 - 0.024 14.5 0.0 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma_1_2 PF03084.14 EGO25864.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family Myb_DNA-bind_4 PF13837.6 EGO25865.1 - 0.033 14.6 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain NB-ARC PF00931.22 EGO25866.1 - 1.7e-06 27.4 0.0 2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGO25866.1 - 1.5e-05 25.4 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGO25866.1 - 0.00026 20.5 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 EGO25866.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGO25866.1 - 0.018 14.9 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGO25866.1 - 0.024 14.4 0.1 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO25866.1 - 0.048 13.4 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Nudix_N PF12535.8 EGO25866.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal AAA PF00004.29 EGO25866.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGO25866.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EGO25866.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EGO25866.1 - 0.18 11.2 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein RuvB_N PF05496.12 EGO25866.1 - 0.19 11.5 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO25866.1 - 0.19 11.7 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Autophagy_N PF03986.13 EGO25867.1 - 2.6e-41 140.8 0.2 5e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGO25867.1 - 3.4e-17 62.8 0.2 6.3e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGO25867.1 - 1.3e-12 47.0 2.9 2.5e-12 46.1 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal TPR_14 PF13428.6 EGO25868.1 - 4.4e-23 80.0 26.5 0.00059 20.4 0.0 12.3 4 2 9 13 13 13 6 Tetratricopeptide repeat HAT PF02184.16 EGO25868.1 - 8e-20 70.5 53.2 4.3e-08 33.0 4.1 12.6 12 2 0 12 12 11 5 HAT (Half-A-TPR) repeat Suf PF05843.14 EGO25868.1 - 1.7e-14 54.5 12.2 1e-05 25.7 0.2 6.4 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGO25868.1 - 2e-13 50.7 0.6 0.026 15.0 0.0 6.5 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25868.1 - 5.4e-13 48.0 0.6 0.14 12.3 0.0 8.8 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25868.1 - 8.8e-09 35.2 0.0 2.1e-05 24.6 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25868.1 - 1.7e-07 30.9 3.1 25 5.4 0.0 8.2 8 1 0 8 8 8 0 Tetratricopeptide repeat SNAP PF14938.6 EGO25868.1 - 1.7e-06 27.7 1.8 0.00028 20.4 1.0 3.1 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 EGO25868.1 - 7.6e-06 25.5 0.1 6.4 6.8 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25868.1 - 9.8e-06 25.8 7.7 0.026 14.8 0.0 5.6 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25868.1 - 1.1e-05 25.9 13.8 0.18 12.5 0.0 6.6 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGO25868.1 - 2.2e-05 23.8 19.2 0.14 11.4 0.0 5.5 2 2 4 6 6 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGO25868.1 - 4.1e-05 23.5 18.1 1.3 9.0 0.1 7.2 3 2 1 5 5 5 2 Mad3/BUB1 homology region 1 TPR_7 PF13176.6 EGO25868.1 - 0.00058 19.7 1.0 5.2 7.3 0.0 5.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO25868.1 - 0.0012 18.5 0.0 3.4 7.4 0.0 4.6 4 1 0 4 4 4 1 TPR repeat TPR_9 PF13371.6 EGO25868.1 - 0.0014 18.7 5.3 1.3 9.2 0.1 5.1 4 1 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EGO25868.1 - 0.011 15.7 4.7 1.9 8.4 0.0 3.4 2 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF3836 PF12930.7 EGO25868.1 - 0.33 10.7 5.1 5 6.9 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF3836) TPR_6 PF13174.6 EGO25868.1 - 0.58 10.9 12.8 36 5.3 0.0 7.6 9 2 0 9 9 5 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EGO25868.1 - 1.6 9.1 7.8 3 8.1 0.4 4.2 4 1 1 5 5 5 0 c-SKI Smad4 binding domain U3_assoc_6 PF08640.11 EGO25868.1 - 2.5 8.2 19.9 0.22 11.6 0.5 6.0 5 2 2 7 7 6 0 U3 small nucleolar RNA-associated protein 6 Lipase_3 PF01764.25 EGO25869.1 - 2.8e-23 82.4 0.0 4.5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO25869.1 - 0.068 13.8 0.3 0.1 13.2 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO25869.1 - 0.081 12.2 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pec_lyase_N PF04431.13 EGO25870.1 - 0.14 12.5 0.1 0.23 11.7 0.1 1.5 1 1 0 1 1 1 0 Pectate lyase, N terminus Gti1_Pac2 PF09729.9 EGO25874.1 - 1.9e-23 83.5 0.2 4.4e-20 72.5 0.0 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 EGO25877.1 - 1.7e-30 106.4 0.0 2.8e-26 92.7 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_1e PF01406.19 EGO25879.1 - 3.6e-129 430.4 0.1 6.2e-129 429.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGO25879.1 - 3e-08 32.8 0.4 7.7e-05 21.6 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EGO25879.1 - 3.3e-05 24.3 0.0 9.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 EGO25879.1 - 3.8e-05 22.1 1.7 0.0019 16.5 0.0 2.7 4 0 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) DUF3326 PF11805.8 EGO25879.1 - 0.11 11.4 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) GAF PF01590.26 EGO25880.1 - 0.0032 18.1 0.0 0.0041 17.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EGO25880.1 - 0.0057 17.0 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GLTP PF08718.11 EGO25881.1 - 1.8e-46 158.1 0.1 2.3e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Codanin-1_C PF15296.6 EGO25881.1 - 0.061 13.4 0.3 0.12 12.4 0.3 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus bZIP_2 PF07716.15 EGO25884.1 - 4.8e-10 39.4 12.7 4.8e-10 39.4 12.7 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EGO25884.1 - 5.9e-06 26.3 7.3 1.5e-05 25.0 7.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 EGO25884.1 - 0.15 12.4 0.3 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 EGO25884.1 - 3.5 8.2 9.0 0.51 10.9 4.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TPR_MLP1_2 PF07926.12 EGO25884.1 - 6.4 6.9 10.2 0.25 11.4 3.9 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Arf PF00025.21 EGO25887.1 - 9.1e-37 126.2 0.0 1.7e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGO25887.1 - 6.9e-10 38.6 0.0 0.00013 21.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGO25887.1 - 7.9e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGO25887.1 - 2.3e-07 30.4 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EGO25887.1 - 1.3e-06 28.1 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGO25887.1 - 1.4e-05 24.6 0.0 2.4e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGO25887.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO25887.1 - 0.00063 19.3 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGO25887.1 - 0.0022 18.5 0.3 0.0036 17.8 0.3 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EGO25887.1 - 0.0027 18.3 1.1 0.0037 17.8 1.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO25887.1 - 0.0055 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO25887.1 - 0.0071 16.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EGO25887.1 - 0.0095 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGO25887.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EGO25887.1 - 0.03 14.9 0.5 0.076 13.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EGO25887.1 - 0.035 13.8 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase cobW PF02492.19 EGO25887.1 - 0.039 13.5 0.1 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EGO25887.1 - 0.051 12.8 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EGO25887.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGO25887.1 - 0.059 12.7 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGO25887.1 - 0.078 13.4 0.1 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGO25887.1 - 0.078 13.1 0.2 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 EGO25887.1 - 0.086 11.7 0.0 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 EGO25887.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 EGO25887.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 EGO25887.1 - 0.13 12.7 3.6 0.64 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EGO25887.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATP-synt_C PF00137.21 EGO25888.1 - 2.2e-24 85.6 32.4 2.6e-15 56.5 11.5 2.5 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 EGO25888.1 - 0.33 11.4 0.6 6 7.3 0.2 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.24 EGO25888.1 - 0.75 9.4 8.4 0.5 10.0 3.8 2.9 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Rubis-subs-bind PF09273.11 EGO25889.1 - 1.1e-12 48.8 0.0 2.7e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 EGO25889.1 - 2.2e-12 47.7 0.0 7.6e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 SET domain Aha1_N PF09229.11 EGO25889.1 - 0.13 12.4 0.4 2.4 8.4 0.7 2.2 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal FAD_binding_3 PF01494.19 EGO25890.1 - 1.7e-17 63.8 0.0 2.9e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGO25890.1 - 1.6e-08 34.0 0.5 2.2e-07 30.3 0.5 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EGO25890.1 - 8.4e-08 31.5 0.3 1.7e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 EGO25890.1 - 1.1e-06 28.3 0.2 0.0021 17.4 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO25890.1 - 1.5e-06 28.3 0.3 3.6e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO25890.1 - 2e-06 27.3 0.3 0.0006 19.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO25890.1 - 5.5e-06 25.7 1.1 1.1e-05 24.8 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO25890.1 - 7.2e-05 22.5 5.3 0.00021 21.0 2.3 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO25890.1 - 9.9e-05 22.8 1.0 0.0053 17.3 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO25890.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO25890.1 - 0.00025 20.3 0.3 0.0005 19.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGO25890.1 - 0.0016 17.2 0.5 0.0084 14.9 0.5 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EGO25890.1 - 0.014 14.5 0.8 0.023 13.8 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Terpene_synth PF01397.21 EGO25892.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Metallophos PF00149.28 EGO25893.1 - 5.8e-36 124.9 0.3 7.3e-36 124.6 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO25893.1 - 0.1 13.0 0.9 0.22 12.0 0.9 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGO25893.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-CCCH PF00642.24 EGO25896.1 - 2.1e-09 37.0 2.7 5e-09 35.8 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EGO25896.1 - 7.6e-08 32.1 5.8 1.3e-07 31.3 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO25896.1 - 1.8e-06 27.8 9.6 3.1e-06 27.1 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO25896.1 - 7.6e-06 25.9 6.5 1.5e-05 24.9 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EGO25896.1 - 1.3e-05 25.1 4.4 3.1e-05 23.9 4.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 EGO25896.1 - 3.8e-05 23.4 9.3 7e-05 22.6 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGO25896.1 - 0.00017 21.7 3.1 0.00038 20.5 3.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 EGO25896.1 - 0.00021 21.1 10.6 0.00041 20.2 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO25896.1 - 0.00045 20.3 7.2 0.001 19.1 7.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGO25896.1 - 0.00093 19.5 8.2 0.0018 18.6 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 EGO25896.1 - 0.0013 18.5 2.9 0.0032 17.2 2.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RanBP PF00641.18 EGO25896.1 - 0.025 13.9 1.2 0.062 12.6 1.2 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Prok-RING_4 PF14447.6 EGO25896.1 - 0.028 14.3 7.7 0.054 13.4 7.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 KI67R PF08065.12 EGO25896.1 - 0.1 13.1 1.4 0.34 11.5 1.4 2.0 1 1 0 1 1 1 0 KI67R (NUC007) repeat adh_short PF00106.25 EGO25897.1 - 5.5e-34 117.3 0.4 7.3e-34 116.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO25897.1 - 8.2e-31 107.4 0.3 1.1e-30 106.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO25897.1 - 9.1e-06 25.7 1.4 7.4e-05 22.7 1.4 2.1 1 1 0 1 1 1 1 KR domain FMN_red PF03358.15 EGO25897.1 - 0.045 13.5 0.6 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 NADPH-dependent FMN reductase 2-Hacid_dh_C PF02826.19 EGO25897.1 - 0.18 11.2 0.2 0.29 10.5 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3232 PF11554.8 EGO25897.1 - 0.21 12.0 0.0 0.49 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) AdoHcyase_NAD PF00670.21 EGO25897.1 - 1.1 9.3 4.5 1.8 8.6 3.3 1.9 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Voltage_CLC PF00654.20 EGO25898.1 - 9.8e-89 298.1 34.5 1.3e-88 297.6 34.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EGO25898.1 - 7.4e-09 35.9 0.1 0.00086 19.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain TPR_12 PF13424.6 EGO25900.1 - 4.6e-44 148.6 14.5 2.8e-18 66.0 0.7 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGO25900.1 - 6.4e-42 140.3 3.9 1.2e-11 44.1 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.22 EGO25900.1 - 1.4e-19 70.3 0.0 2.1e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 EGO25900.1 - 2.3e-17 61.7 9.7 4e-05 23.3 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO25900.1 - 3.4e-14 52.0 6.2 0.00012 21.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25900.1 - 1.4e-11 43.6 5.3 0.0065 16.5 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25900.1 - 4.7e-10 38.9 8.1 0.0036 17.4 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25900.1 - 1.2e-07 31.6 3.3 1.8 9.1 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO25900.1 - 1.4e-06 28.7 3.4 0.053 14.0 0.1 4.3 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO25900.1 - 4.9e-06 26.2 1.7 4.9e-06 26.2 1.7 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EGO25900.1 - 2.5e-05 24.7 1.2 24 6.1 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 EGO25900.1 - 3.3e-05 24.3 0.1 8.1e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 EGO25900.1 - 5.2e-05 23.8 6.3 0.15 12.7 0.4 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TniB PF05621.11 EGO25900.1 - 0.002 17.6 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein TPR_4 PF07721.14 EGO25900.1 - 0.0029 18.1 0.0 62 4.7 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 EGO25900.1 - 0.004 17.3 1.5 3.3 8.2 0.0 4.3 4 0 0 4 4 4 1 PPR repeat TPR_3 PF07720.12 EGO25900.1 - 0.005 16.8 6.9 7.5 6.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP68 PF16969.5 EGO25900.1 - 0.0056 15.7 1.2 8.4 5.3 0.1 3.2 3 0 0 3 3 3 0 RNA-binding signal recognition particle 68 ANAPC3 PF12895.7 EGO25900.1 - 0.0086 16.3 6.1 4.1 7.7 0.7 4.1 2 1 2 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGO25900.1 - 0.0097 16.0 2.2 3.1 7.9 0.2 3.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain ThiC-associated PF13667.6 EGO25900.1 - 0.021 14.6 1.0 12 5.7 0.1 3.2 2 1 1 3 3 3 0 ThiC-associated domain NACHT PF05729.12 EGO25900.1 - 0.048 13.6 0.0 0.15 11.9 0.0 2.0 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EGO25900.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGO25900.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SlpA PF03217.14 EGO25900.1 - 0.29 11.8 4.0 16 6.1 0.1 3.4 3 0 0 3 3 3 0 Surface later protein A domain TPR_11 PF13414.6 EGO25900.1 - 5.3 6.8 9.6 6.3 6.6 0.3 3.9 4 0 0 4 4 4 0 TPR repeat DKNYY PF13644.6 EGO25902.1 - 0.0037 18.0 0.5 0.0047 17.7 0.5 1.1 1 0 0 1 1 1 1 DKNYY family DUF4939 PF16297.5 EGO25902.1 - 0.025 14.5 0.1 0.026 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Plavaka PF18759.1 EGO25904.1 - 1.1e-107 360.1 0.2 1.3e-107 359.8 0.2 1.1 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 EGO25904.1 - 0.012 16.0 3.5 0.048 14.1 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type MVL PF12151.8 EGO25904.1 - 1.3 8.9 3.5 6.9 6.6 0.3 2.7 2 0 0 2 2 2 0 Mannan-binding protein zf-CCHC PF00098.23 EGO25905.1 - 8.6e-08 31.9 2.8 8.6e-08 31.9 2.8 1.6 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO25905.1 - 1.1e-06 28.8 0.0 3.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein PIG-U PF06728.13 EGO25907.1 - 9.3e-101 337.6 31.8 1.1e-100 337.4 31.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 4HB_MCP_1 PF12729.7 EGO25909.1 - 0.0045 16.5 0.4 0.0061 16.1 0.4 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction LPP PF04728.13 EGO25909.1 - 0.0072 16.7 1.1 0.016 15.6 1.1 1.5 1 0 0 1 1 1 1 Lipoprotein leucine-zipper AIP3 PF03915.13 EGO25909.1 - 0.036 13.2 0.4 0.046 12.8 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Peptidase_S64 PF08192.11 EGO25909.1 - 0.045 12.3 0.1 0.052 12.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mu-like_Pro PF10123.9 EGO25909.1 - 0.074 12.6 0.2 0.084 12.4 0.2 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein GrpE PF01025.19 EGO25909.1 - 0.12 12.0 0.8 0.17 11.5 0.8 1.2 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 EGO25909.1 - 0.15 11.8 1.2 0.23 11.3 1.2 1.2 1 0 0 1 1 1 0 Septum formation initiator C2 PF00168.30 EGO25910.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 C2 domain PDE8 PF08629.10 EGO25911.1 - 1.8e-07 31.0 10.1 0.062 13.3 0.4 4.5 3 1 1 4 4 4 4 PDE8 phosphodiesterase PspB PF06667.12 EGO25911.1 - 0.038 14.1 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Phage shock protein B CCDC24 PF15669.5 EGO25911.1 - 0.094 12.6 0.3 0.18 11.7 0.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Clathrin-link PF09268.10 EGO25911.1 - 0.65 9.4 9.3 16 4.9 0.2 3.7 4 0 0 4 4 4 0 Clathrin, heavy-chain linker Pkinase PF00069.25 EGO25912.1 - 1.5e-07 31.0 0.0 2.5e-05 23.8 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25912.1 - 0.0044 16.3 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGO25914.1 - 4.9e-08 32.7 0.0 1.9e-05 24.1 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25914.1 - 0.0055 16.0 0.0 0.091 12.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4229 PF14012.6 EGO25916.1 - 0.04 14.0 0.5 0.045 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) 6PF2K PF01591.18 EGO25917.1 - 6.6e-58 195.6 0.2 8.6e-58 195.3 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGO25917.1 - 5.7e-36 124.0 0.0 9.9e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chitin_synth_2 PF03142.15 EGO25918.1 - 1.8e-231 769.4 1.0 2.6e-231 768.8 1.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGO25918.1 - 1.7e-102 343.9 0.0 3.9e-102 342.7 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EGO25918.1 - 3.9e-16 59.0 0.6 3.1e-11 43.3 0.0 3.3 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EGO25918.1 - 5.2e-16 59.2 0.0 5.9e-14 52.5 0.0 2.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 EGO25918.1 - 4e-15 55.5 0.1 1.2e-14 54.0 0.1 1.9 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGO25918.1 - 2.8e-14 53.5 3.0 6.6e-14 52.3 3.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO25918.1 - 3.1e-09 36.9 0.0 3.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO25918.1 - 0.00019 21.0 0.0 0.0039 16.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF87 PF01935.17 EGO25918.1 - 0.068 13.3 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Jiv90 PF14901.6 EGO25918.1 - 0.093 12.9 0.2 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone DUF3084 PF11283.8 EGO25918.1 - 0.53 10.3 2.3 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) RSRP PF17069.5 EGO25919.1 - 0.035 13.7 2.0 0.069 12.7 0.2 2.0 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 DDR PF08841.10 EGO25919.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain ADH_N PF08240.12 EGO25920.1 - 7.7e-07 29.0 0.1 1.1e-05 25.3 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF1690 PF07956.11 EGO25923.1 - 2.4e-39 135.0 4.6 2.8e-39 134.7 4.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Use1 PF09753.9 EGO25924.1 - 2.5e-15 56.9 0.0 5.9e-15 55.7 0.0 1.6 2 1 1 3 3 3 1 Membrane fusion protein Use1 DUF4195 PF13836.6 EGO25924.1 - 0.01 15.9 0.8 0.018 15.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Acyltransferase PF01553.21 EGO25926.1 - 1.3e-20 73.4 0.0 2.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGO25926.1 - 7.5e-06 25.9 0.5 6e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Acyltransferase C-terminus Sun2_CC2 PF18580.1 EGO25926.1 - 0.22 11.8 0.0 0.44 10.8 0.0 1.4 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 GST_N_2 PF13409.6 EGO25928.1 - 8.5e-11 42.0 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO25928.1 - 5e-10 39.6 0.0 1.8e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO25928.1 - 3.7e-05 23.8 0.0 8.9e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO25928.1 - 0.00014 22.1 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO25928.1 - 0.00081 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO25928.1 - 0.026 14.9 0.2 0.2 12.0 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DASH_Dad4 PF08650.10 EGO25929.1 - 1.7e-25 88.7 1.3 1.8e-25 88.7 1.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 IMPa_helical PF18642.1 EGO25929.1 - 0.076 13.4 0.0 0.086 13.3 0.0 1.1 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain zinc_ribbon_16 PF17034.5 EGO25930.1 - 1.1e-17 64.4 4.5 1.1e-17 64.4 4.5 2.6 2 1 1 3 3 3 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EGO25930.1 - 0.00043 19.8 4.7 0.00043 19.8 4.7 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EGO25930.1 - 0.0035 18.1 2.2 2.4 9.2 0.2 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DZR PF12773.7 EGO25930.1 - 0.45 10.6 5.7 1.1 9.3 3.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon Glyco_tranf_2_3 PF13641.6 EGO25931.1 - 4.9e-29 101.8 0.0 6.8e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGO25931.1 - 1.4e-08 34.8 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO25931.1 - 4.1e-07 29.6 0.0 2.3e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 IBR PF01485.21 EGO25932.1 - 1.7e-14 53.8 40.3 5.7e-09 36.1 17.1 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGO25932.1 - 4.8e-06 26.3 2.0 4.8e-06 26.3 2.0 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO25932.1 - 0.00013 21.8 3.2 0.00013 21.8 3.2 4.2 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO25932.1 - 0.0052 16.6 4.1 0.0052 16.6 4.1 4.4 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO25932.1 - 0.0055 16.7 4.2 0.0055 16.7 4.2 4.2 3 2 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGO25932.1 - 4 7.8 41.7 0.043 14.2 6.1 3.9 3 1 0 3 3 3 0 Ring finger domain zf-RING_4 PF14570.6 EGO25932.1 - 6.4 6.7 20.3 0.5 10.2 3.5 3.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain tRNA-synt_2 PF00152.20 EGO25933.1 - 1.4e-75 254.3 0.0 2e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO25933.1 - 2e-12 46.9 0.1 3.6e-11 42.9 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO25933.1 - 1.7e-08 34.3 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) HSP70 PF00012.20 EGO25934.1 - 4.8e-161 536.9 0.2 1.5e-160 535.3 0.0 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGO25934.1 - 9.7e-13 47.6 0.1 3.2e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein DUF3295 PF11702.8 EGO25934.1 - 0.18 11.1 1.5 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) ACCA PF03255.14 EGO25934.1 - 0.3 11.0 3.8 0.14 12.1 0.5 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PC-Esterase PF13839.6 EGO25937.1 - 2.2e-05 24.3 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Retrotrans_gag PF03732.17 EGO25942.1 - 0.0011 19.1 0.3 0.0034 17.6 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein FdhE PF04216.12 EGO25942.1 - 0.066 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation IF2_N PF04760.15 EGO25943.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Mito_carr PF00153.27 EGO25945.1 - 8.4e-62 205.1 3.6 1.8e-20 72.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 EGO25947.1 - 6.2e-08 32.7 4.2 0.0024 18.2 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO25947.1 - 7.1e-06 26.2 1.6 0.059 13.8 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO25947.1 - 1.3e-05 25.6 3.2 0.041 14.7 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGO25947.1 - 0.013 15.8 1.9 1.5 9.3 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO25947.1 - 0.027 14.8 4.5 3.6 8.0 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Fer4_9 PF13187.6 EGO25947.1 - 0.028 14.6 1.0 0.059 13.6 1.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-C2H2_11 PF16622.5 EGO25947.1 - 0.087 12.6 0.2 11 5.9 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type NUDIX PF00293.28 EGO25949.1 - 1.8e-17 63.6 0.0 3.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EGO25949.1 - 4.6e-14 52.9 0.0 1.1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EGO25949.1 - 0.018 14.7 0.3 0.034 13.8 0.3 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Glyco_hydro_18 PF00704.28 EGO25950.1 - 8.4e-59 199.8 0.2 1e-58 199.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGO25950.1 - 0.0024 17.4 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 CoA_binding_2 PF13380.6 EGO25951.1 - 6.1e-28 97.7 0.0 6.8e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain PALP PF00291.25 EGO25952.1 - 1.8e-58 198.3 0.2 4.8e-29 101.7 0.1 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 EGO25956.1 - 1.6e-54 185.3 0.0 3.7e-52 177.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CbiG_N PF11760.8 EGO25956.1 - 0.089 12.8 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Myb_DNA-binding PF00249.31 EGO25957.1 - 1.2e-11 44.6 0.1 2.2e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 EGO25957.1 - 1.5e-10 41.3 0.0 3.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EGO25957.1 - 0.0003 21.0 0.0 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_19 PF14559.6 EGO25959.1 - 3.1e-29 101.3 29.1 5.7e-05 23.6 0.1 11.1 9 2 2 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGO25959.1 - 2.6e-21 74.0 48.8 0.018 15.1 0.0 15.1 17 0 0 17 17 16 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGO25959.1 - 3e-21 74.3 30.3 0.00097 18.9 0.0 11.8 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGO25959.1 - 6.2e-17 61.7 36.7 4.1e-06 27.0 0.9 9.7 7 3 3 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGO25959.1 - 2.3e-14 52.3 30.1 0.0078 16.3 0.0 12.5 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO25959.1 - 1.2e-12 47.5 47.7 0.059 14.2 0.2 15.0 13 4 5 18 18 14 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGO25959.1 - 3.1e-11 43.1 28.6 0.004 17.7 0.1 11.9 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO25959.1 - 2.5e-10 40.0 18.3 3.3 8.3 0.4 10.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO25959.1 - 3.3e-10 39.2 25.2 0.032 14.3 0.3 9.8 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGO25959.1 - 2.6e-08 33.4 29.3 0.012 15.4 0.2 10.2 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO25959.1 - 3.9e-08 33.8 42.1 0.0067 17.1 0.1 10.5 11 2 0 11 11 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO25959.1 - 2.4e-06 27.7 15.9 0.016 15.5 1.1 5.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGO25959.1 - 3.7e-06 26.5 13.2 3.2 7.5 0.0 9.2 9 1 1 10 10 10 2 TPR repeat PknG_TPR PF16918.5 EGO25959.1 - 0.00027 19.8 10.7 0.17 10.6 0.0 4.5 5 0 0 5 5 5 2 Protein kinase G tetratricopeptide repeat DUF2989 PF11207.8 EGO25959.1 - 0.0012 18.6 13.0 0.093 12.5 0.0 5.6 5 1 0 5 5 4 2 Protein of unknown function (DUF2989) TPR_4 PF07721.14 EGO25959.1 - 0.039 14.6 0.0 0.039 14.6 0.0 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat Peptidase_C12 PF01088.21 EGO25960.1 - 4.3e-45 154.0 0.0 6.4e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Plavaka PF18759.1 EGO25961.1 - 5e-59 200.1 4.1 4.8e-39 134.5 0.1 2.6 2 1 1 3 3 3 2 Plavaka transposase Chromo PF00385.24 EGO25961.1 - 9.3e-09 35.1 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase_fungal PF17667.1 EGO25962.1 - 3.8e-16 58.9 0.0 7.2e-16 58.0 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Viral_helicase1 PF01443.18 EGO25962.1 - 0.16 11.7 0.8 1.7 8.3 0.0 2.4 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase Pkinase_fungal PF17667.1 EGO25963.1 - 1.2e-19 70.4 0.0 1.4e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Retrotrans_gag PF03732.17 EGO25964.1 - 1.2e-05 25.5 1.5 2.7e-05 24.4 1.5 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein LytR_C PF13399.6 EGO25965.1 - 0.069 14.1 0.0 0.14 13.2 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator UbiA PF01040.18 EGO25966.1 - 1.3e-16 60.6 13.7 2.1e-16 60.0 13.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family RNase_T PF00929.24 EGO25969.1 - 5.8e-05 23.7 0.0 8.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 EGO25969.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.3 1 0 0 1 1 1 0 ElonginA binding-protein 1 Asp PF00026.23 EGO25970.1 - 1.2e-63 215.4 5.4 1.5e-63 215.1 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO25970.1 - 5.2e-13 49.6 3.8 1.5e-09 38.3 3.6 2.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.18 EGO25971.1 - 1.3e-09 37.5 0.0 2.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO25971.1 - 8.6e-06 25.8 16.2 8.6e-06 25.8 16.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.20 EGO25973.1 - 3e-76 256.9 0.0 3.6e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO25973.1 - 0.00024 20.6 1.1 0.00048 19.6 0.5 1.8 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO25973.1 - 0.00054 19.4 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FUSC_2 PF13515.6 EGO25974.1 - 1.7e-15 57.3 6.7 1.7e-15 57.3 6.7 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EGO25974.1 - 1.9e-09 37.7 0.1 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EGO25974.1 - 3.9e-05 22.7 5.4 0.0028 16.6 1.9 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 EGO25974.1 - 0.00025 19.8 14.8 0.045 12.3 2.2 3.6 2 2 0 2 2 2 2 Fusaric acid resistance protein family DUF2787 PF10980.8 EGO25974.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2787) ArAE_2_N PF10337.9 EGO25974.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal FUSC-like PF12805.7 EGO25974.1 - 0.087 11.9 4.9 2.1 7.4 1.1 2.4 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS SQS_PSY PF00494.19 EGO25974.1 - 0.13 11.8 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Squalene/phytoene synthase API5 PF05918.11 EGO25975.1 - 1.4e-29 103.3 1.3 1.8e-29 103.0 0.0 1.7 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) Cnd1 PF12717.7 EGO25975.1 - 0.01 15.9 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO25975.1 - 0.069 13.6 0.1 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats DUF384 PF04064.13 EGO25975.1 - 0.12 12.2 3.1 14 5.6 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF384) Cytochrom_B561 PF03188.16 EGO25976.1 - 3.2e-11 43.5 6.1 4.8e-11 42.9 6.1 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EGO25976.1 - 0.02 15.0 4.5 0.02 15.0 4.5 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF2615 PF11027.8 EGO25976.1 - 0.14 12.3 0.3 7.7 6.7 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2615) DUF2427 PF10348.9 EGO25976.1 - 0.88 9.4 11.2 0.024 14.4 3.2 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF2427) DUF420 PF04238.12 EGO25976.1 - 3.7 7.8 13.9 6.9 7.0 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF420) S-methyl_trans PF02574.16 EGO25977.1 - 9.7e-50 169.8 0.0 1.2e-49 169.5 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase HTH_31 PF13560.6 EGO25977.1 - 0.0059 16.9 0.6 5.1 7.5 0.1 3.2 3 0 0 3 3 3 2 Helix-turn-helix domain Pkinase PF00069.25 EGO25978.1 - 4.8e-70 235.9 0.0 6.2e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO25978.1 - 3.3e-37 128.2 0.0 5.1e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGO25978.1 - 9.1e-17 61.2 0.0 1.9e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EGO25978.1 - 5.8e-06 25.8 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 EGO25978.1 - 6.1e-06 26.5 0.0 3.6e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGO25978.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO25978.1 - 0.00027 21.0 0.0 0.023 14.6 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family FHA_2 PF17913.1 EGO25978.1 - 0.004 17.4 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Haspin_kinase PF12330.8 EGO25978.1 - 0.0047 15.9 0.1 0.0079 15.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGO25978.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Zn_clus PF00172.18 EGO25979.1 - 0.0001 22.3 8.7 0.00013 22.0 6.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2457 PF10446.9 EGO25979.1 - 0.88 8.6 9.5 1 8.4 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hepatitis_core PF00906.20 EGO25979.1 - 8.4 5.9 8.4 0.98 8.9 4.2 1.5 2 0 0 2 2 2 0 Hepatitis core antigen SPC22 PF04573.12 EGO25981.1 - 5.4e-46 156.2 0.1 6.2e-46 156.0 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF5565 PF17720.1 EGO25981.1 - 0.0091 14.9 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5565) Acyltransferase PF01553.21 EGO25982.1 - 2.7e-16 59.4 0.0 4.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Fanconi_C PF02106.15 EGO25982.1 - 0.45 9.2 2.3 0.5 9.0 0.8 1.6 2 0 0 2 2 2 0 Fanconi anaemia group C protein Lipase_3 PF01764.25 EGO25983.1 - 1.5e-29 102.7 0.0 2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGO25983.1 - 0.15 11.6 0.1 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.20 EGO25983.1 - 0.18 11.4 0.1 0.29 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Ribosomal_S2 PF00318.20 EGO25984.1 - 1.6e-29 102.7 0.2 4.2e-15 55.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGO25984.1 - 2.2e-08 35.4 8.4 3.8e-08 34.6 8.4 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus SelK_SelG PF10961.8 EGO25986.1 - 0.14 12.7 0.4 0.53 10.9 0.4 2.0 1 0 0 1 1 1 0 Selenoprotein SelK_SelG B277 PF17623.2 EGO25987.1 - 0.067 12.3 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Methyltransf_22 PF13383.6 EGO25988.1 - 1.7e-21 76.9 0.0 2.2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EGO25988.1 - 1.9e-08 34.5 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF1892 PF08987.10 EGO25988.1 - 0.051 13.8 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) Glyoxalase PF00903.25 EGO25989.1 - 5.7e-24 84.7 0.0 6.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGO25989.1 - 2.8e-06 27.5 0.0 1.2e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGO25989.1 - 7.2e-05 23.5 0.0 0.00011 22.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EGO25989.1 - 0.0019 18.1 0.0 0.19 11.7 0.1 2.3 2 1 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 EGO25989.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Glyoxalase_3 PF13468.6 EGO25989.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Nefa_Nip30_N PF10187.9 EGO25990.1 - 1.6e-31 108.7 12.3 1.6e-31 108.7 12.3 2.0 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 EGO25990.1 - 0.13 11.8 17.7 0.15 11.7 17.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ig_mannosidase PF17753.1 EGO25991.1 - 2.6e-13 49.5 0.0 1.6e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 EGO25991.1 - 1.5e-12 48.0 0.6 1.5e-12 48.0 0.6 1.9 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EGO25991.1 - 0.0019 18.8 0.0 0.005 17.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 LRR_8 PF13855.6 EGO25992.1 - 5e-40 135.1 60.4 6.8e-10 38.6 0.6 10.6 4 3 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 EGO25992.1 - 1e-39 133.9 75.2 8.2e-07 29.3 3.5 12.8 5 3 4 12 12 12 12 Leucine Rich repeats (2 copies) PP2C PF00481.21 EGO25992.1 - 7.1e-39 134.0 0.0 1.2e-38 133.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 EGO25992.1 - 5.5e-21 75.0 0.0 1e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EGO25992.1 - 2.3e-07 30.5 25.5 0.00031 20.3 2.1 5.6 2 1 3 5 5 5 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 EGO25992.1 - 4.7e-05 23.0 0.0 0.00023 20.8 0.0 2.2 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 EGO25992.1 - 0.034 14.7 61.1 0.29 11.9 0.2 14.5 15 2 0 15 15 15 0 Leucine Rich Repeat LRR_6 PF13516.6 EGO25992.1 - 2.2 8.5 47.4 5.8 7.2 0.2 12.8 15 0 0 15 15 15 0 Leucine Rich repeat Mg_trans_NIPA PF05653.14 EGO25993.1 - 1.8e-81 273.5 30.6 2.3e-81 273.2 30.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGO25993.1 - 6.2e-08 32.9 8.6 6.2e-08 32.9 8.6 3.5 3 1 0 3 3 3 2 EamA-like transporter family G-alpha PF00503.20 EGO25997.1 - 1.6e-113 379.5 0.0 1.8e-113 379.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO25997.1 - 1.2e-11 44.4 0.4 2.1e-07 30.6 0.0 2.9 2 1 1 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 EGO25997.1 - 0.01 16.1 0.0 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGO25997.1 - 0.014 14.7 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 EGO25997.1 - 0.047 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NOG1_N PF17835.1 EGO25998.1 - 1.8e-49 167.8 0.7 1.8e-49 167.8 0.7 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EGO25998.1 - 3.2e-27 94.3 2.3 4.4e-27 93.8 1.2 1.9 1 1 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EGO25998.1 - 4.8e-27 93.5 0.1 1.5e-26 91.9 0.0 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EGO25998.1 - 7.2e-17 61.5 0.0 1.9e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO25998.1 - 7.1e-11 41.9 0.1 1.7e-10 40.6 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO25998.1 - 0.0018 18.2 0.1 0.82 9.5 0.0 3.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGO25998.1 - 0.0072 16.4 0.9 1.8 8.6 0.0 3.1 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 EGO25998.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Sushi_2 PF09014.10 EGO25998.1 - 0.058 13.3 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AAA_16 PF13191.6 EGO25998.1 - 0.061 13.7 0.0 0.67 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_M24 PF00557.24 EGO25999.1 - 1.1e-42 146.1 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EGO25999.1 - 1.7e-41 142.0 0.0 4.7e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGO25999.1 - 9.5e-21 73.6 0.7 3.6e-20 71.8 0.7 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EGO25999.1 - 1.2e-14 55.1 0.0 1.2e-13 51.8 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain LpqV PF17301.2 EGO25999.1 - 0.25 11.6 0.9 10 6.4 0.1 3.2 3 0 0 3 3 3 0 Putative lipoprotein LpqV DPM3 PF08285.11 EGO26000.1 - 0.053 13.7 0.3 0.073 13.3 0.3 1.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Sugar_tr PF00083.24 EGO26001.1 - 8.4e-85 285.3 26.3 9.7e-85 285.1 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO26001.1 - 4.4e-26 91.7 26.3 4.4e-26 91.7 26.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO26002.1 - 1.8e-71 241.4 22.2 2.2e-71 241.1 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO26002.1 - 3.9e-20 72.1 30.6 1.9e-12 46.8 13.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM192 PF14802.6 EGO26002.1 - 0.034 13.2 0.7 0.08 12.0 0.1 1.9 2 0 0 2 2 2 0 TMEM192 family Pyridoxal_deC PF00282.19 EGO26004.1 - 2.7e-05 23.1 0.0 0.00034 19.5 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain RVP_2 PF08284.11 EGO26006.1 - 2.7e-06 27.2 0.0 2.9e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO26006.1 - 3.1e-06 27.6 0.0 3.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO26006.1 - 0.00017 22.2 0.0 0.00023 21.7 0.0 1.2 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 EGO26007.1 - 0.0017 18.3 4.1 0.0032 17.5 4.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26007.1 - 0.0054 17.0 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Peptidase_M60_C PF18630.1 EGO26007.1 - 0.084 13.0 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain zf-CCHC_2 PF13696.6 EGO26007.1 - 1.7 8.5 3.8 3.1 7.7 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle V-ATPase_C PF03223.15 EGO26009.1 - 1.2e-116 390.1 0.8 1.4e-116 390.0 0.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GATase_5 PF13507.6 EGO26010.1 - 5.3e-101 337.1 0.0 7.7e-101 336.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGO26010.1 - 1.9e-41 141.8 0.3 1.5e-29 103.1 0.2 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGO26010.1 - 3.3e-30 104.4 0.0 1e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGO26010.1 - 8.8e-22 77.4 0.0 3.5e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EGO26010.1 - 0.072 13.7 0.3 1.1 10.0 0.0 2.7 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain PX PF00787.24 EGO26011.1 - 4.9e-26 90.9 0.0 7.1e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 PX domain Trs65 PF12735.7 EGO26012.1 - 5.5e-23 81.9 0.0 3.2e-16 59.6 0.0 3.6 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 Glyco_hydro_cc PF11790.8 EGO26014.1 - 2.4e-62 210.6 2.9 2.7e-62 210.4 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FBA PF04300.13 EGO26014.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box associated region Tetraspanin PF00335.20 EGO26015.1 - 0.00041 20.1 4.4 0.00041 20.1 4.4 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF2749 PF10907.8 EGO26015.1 - 0.14 12.3 0.1 0.41 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF2070 PF09843.9 EGO26015.1 - 2 6.6 5.4 2.6 6.3 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BCS1_N PF08740.11 EGO26017.1 - 7.3e-40 136.9 1.7 2.1e-39 135.4 1.7 1.9 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGO26017.1 - 1e-14 55.1 0.0 6.1e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGO26017.1 - 0.0004 20.1 0.1 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 EGO26017.1 - 0.00096 18.4 0.0 0.0022 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGO26017.1 - 0.0086 16.5 3.5 0.022 15.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGO26017.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.4 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGO26017.1 - 0.051 14.1 0.8 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 EGO26017.1 - 0.064 13.7 17.2 13 6.2 0.0 3.2 3 1 1 4 4 4 0 AAA domain ssDNA_TraI_N PF18272.1 EGO26017.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain AAA_33 PF13671.6 EGO26017.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO26017.1 - 0.85 10.2 4.9 2.6 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGO26017.1 - 1.6 8.4 9.3 30 4.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sensor PF13796.6 EGO26018.1 - 2 8.4 25.7 0.086 12.9 16.6 2.7 2 1 1 3 3 3 0 Putative sensor G-alpha PF00503.20 EGO26022.1 - 3.1e-119 398.3 0.1 3.6e-119 398.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO26022.1 - 1.6e-16 60.3 1.1 1.1e-11 44.5 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO26022.1 - 2.9e-05 23.5 0.1 0.003 17.0 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO26022.1 - 0.0045 17.2 0.8 3.1 8.0 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 EGO26022.1 - 0.028 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 EGO26022.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGO26022.1 - 0.054 13.6 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGO26022.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Cyt-b5 PF00173.28 EGO26023.1 - 4.2e-11 42.8 0.1 4.9e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SKI PF01202.22 EGO26028.1 - 0.0041 17.3 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase AAA_29 PF13555.6 EGO26028.1 - 0.0086 15.8 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO26028.1 - 0.011 16.2 0.4 0.021 15.4 0.4 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EGO26028.1 - 0.038 14.2 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO26028.1 - 0.039 14.2 0.0 0.089 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO26028.1 - 0.062 13.9 0.0 0.12 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO26028.1 - 0.067 13.6 0.1 0.16 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin2 PF13189.6 EGO26028.1 - 0.11 12.7 0.0 0.81 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 EGO26028.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 EGO26028.1 - 0.2 11.6 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FLYWCH PF04500.16 EGO26029.1 - 3.3 7.9 4.9 3.8 7.7 0.7 2.2 2 0 0 2 2 2 0 FLYWCH zinc finger domain MMtag PF10159.9 EGO26030.1 - 3.9e-31 107.2 2.5 3.9e-31 107.2 2.5 2.8 3 0 0 3 3 3 1 Multiple myeloma tumor-associated YaaC PF14175.6 EGO26031.1 - 0.053 12.8 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 YaaC-like Protein Ank_2 PF12796.7 EGO26032.1 - 5.9e-15 55.6 0.0 4.3e-07 30.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGO26032.1 - 1e-14 54.2 0.0 2.1e-05 24.8 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGO26032.1 - 6.4e-13 48.6 0.0 1.4e-05 25.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO26032.1 - 2.9e-12 46.8 0.0 0.0003 21.3 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO26032.1 - 2.5e-11 42.7 0.0 0.00085 19.6 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EGO26033.1 - 1.8e-15 57.3 0.1 3.2e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO26033.1 - 8.8e-15 54.9 0.1 1e-10 41.9 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO26033.1 - 1.2e-13 51.0 0.1 4.8e-10 39.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO26033.1 - 4.1e-13 48.2 0.2 4e-05 23.7 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGO26033.1 - 4e-12 46.0 1.4 0.00024 21.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat adh_short PF00106.25 EGO26034.1 - 3.6e-15 55.9 0.0 1.3e-11 44.4 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO26034.1 - 2.1e-07 30.7 0.0 2.1e-05 24.2 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO26034.1 - 0.055 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain ECH_1 PF00378.20 EGO26035.1 - 2.4e-35 122.0 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO26035.1 - 3.5e-22 79.4 0.0 1.2e-18 67.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-CCHC PF00098.23 EGO26036.1 - 1.3e-06 28.2 27.5 0.0012 18.8 1.0 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 EGO26036.1 - 0.00097 18.9 3.4 0.0086 15.9 0.3 4.3 5 0 0 5 5 5 2 Zinc knuckle Apt1 PF10351.9 EGO26036.1 - 0.068 12.0 3.6 0.075 11.9 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-CCHC_4 PF14392.6 EGO26036.1 - 0.28 11.0 23.4 1.3 8.8 0.3 4.4 4 0 0 4 4 4 0 Zinc knuckle Presenilin PF01080.17 EGO26036.1 - 5 5.8 8.2 6.4 5.4 8.2 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGO26036.1 - 7.9 4.6 11.2 11 4.2 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Yippee-Mis18 PF03226.14 EGO26037.1 - 3.6e-15 56.1 0.0 4.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4476 PF14771.6 EGO26037.1 - 0.16 12.3 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) adh_short_C2 PF13561.6 EGO26039.1 - 2.7e-56 190.8 0.0 3.2e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO26039.1 - 1.2e-41 142.4 0.1 1.5e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO26039.1 - 2.9e-11 43.6 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 KR domain IlvN PF07991.12 EGO26040.1 - 2.3e-47 160.6 0.0 3.4e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGO26040.1 - 3.5e-24 85.7 0.6 6.8e-24 84.8 0.6 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EGO26040.1 - 4.1e-08 33.7 0.1 1.1e-07 32.4 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGO26040.1 - 5.8e-06 25.8 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EGO26040.1 - 0.00038 20.6 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EGO26040.1 - 0.00064 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EGO26040.1 - 0.041 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Vps53_N PF04100.12 EGO26041.1 - 3.6e-90 302.7 2.4 7e-90 301.7 2.4 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 EGO26041.1 - 1.5e-07 31.5 3.6 1.9e-07 31.2 0.1 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 EGO26041.1 - 1.8e-07 30.8 6.7 1.8e-07 30.8 6.7 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGO26041.1 - 0.0013 18.6 0.9 0.0013 18.6 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec5 PF15469.6 EGO26041.1 - 0.01 15.7 4.1 0.01 15.7 4.1 2.3 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF4533 PF15047.6 EGO26041.1 - 0.033 13.7 6.7 0.022 14.3 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Mob_Pre PF01076.19 EGO26041.1 - 0.092 12.6 3.6 0.33 10.8 0.6 2.2 2 0 0 2 2 2 0 Plasmid recombination enzyme Bacillus_HBL PF05791.11 EGO26041.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.6 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Apolipoprotein PF01442.18 EGO26041.1 - 0.98 9.3 9.5 0.9 9.4 7.6 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain MapZ_EC1 PF18041.1 EGO26041.1 - 1.8 8.8 7.7 1.7 8.9 0.9 3.6 3 1 1 4 4 4 0 MapZ extracellular domain 1 AHD PF17793.1 EGO26041.1 - 8.9 6.2 6.8 5.8 6.8 0.8 3.3 3 0 0 3 3 3 0 ANC1 homology domain (AHD) gag_pre-integrs PF13976.6 EGO26042.1 - 5.7e-10 38.9 0.3 9e-10 38.3 0.3 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.17 EGO26043.1 - 0.0084 16.4 4.1 0.024 14.9 1.6 2.5 2 1 0 2 2 2 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 EGO26044.1 - 2.3e-15 56.5 0.0 3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Myb_DNA-bind_4 PF13837.6 EGO26045.1 - 0.004 17.5 0.0 0.061 13.7 0.0 2.7 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGO26045.1 - 0.0048 17.9 0.1 0.3 12.1 0.0 2.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pterin_4a PF01329.19 EGO26046.1 - 2.8e-11 43.4 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Beta_elim_lyase PF01212.21 EGO26047.1 - 6.7e-58 196.3 0.0 4.8e-36 124.5 0.0 2.0 2 0 0 2 2 2 2 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGO26047.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO26047.1 - 0.16 10.5 0.0 0.33 9.5 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Urb2 PF10441.9 EGO26048.1 - 6.8e-45 153.5 2.8 6.2e-44 150.4 0.0 3.5 3 0 0 3 3 3 1 Urb2/Npa2 family SPG48 PF14764.6 EGO26048.1 - 0.75 10.3 3.6 44 4.6 0.1 4.4 5 0 0 5 5 5 0 AP-5 complex subunit, vesicle trafficking Aldo_ket_red PF00248.21 EGO26050.1 - 8.2e-26 90.9 0.0 5.3e-24 84.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family PEX11 PF05648.14 EGO26051.1 - 2e-53 181.2 0.6 2.2e-53 181.0 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DnaJ PF00226.31 EGO26053.1 - 1.6e-19 69.8 0.1 3.7e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2681 PF10883.8 EGO26053.1 - 2.4 8.6 9.6 0.19 12.1 3.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF1897 PF09005.10 EGO26055.1 - 2.5 7.7 5.8 11 5.6 5.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1897) GMC_oxred_N PF00732.19 EGO26056.1 - 7.4e-66 222.5 0.0 9.9e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO26056.1 - 8.2e-30 104.2 0.0 1.5e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO26056.1 - 0.0034 16.5 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HydF_tetramer PF18133.1 EGO26056.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain CMAS PF02353.20 EGO26057.1 - 3e-51 174.3 0.1 5.8e-51 173.4 0.1 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO26057.1 - 9.5e-08 32.6 0.0 2.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO26057.1 - 2e-07 31.0 0.1 5.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO26057.1 - 1.5e-06 28.8 0.0 4.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO26057.1 - 0.0022 17.8 0.1 0.0074 16.1 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 EGO26057.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EGO26057.1 - 0.036 14.8 0.0 0.086 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EGO26057.1 - 0.11 12.2 0.1 1.9 8.1 0.1 2.5 2 1 1 3 3 3 0 Putative RNA methylase family UPF0020 E1-E2_ATPase PF00122.20 EGO26058.1 - 1.7e-28 99.3 0.0 1.7e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 EGO26058.1 - 1e-24 87.1 2.2 1.1e-24 87.0 0.0 2.1 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EGO26058.1 - 2.5e-19 70.4 0.3 3.7e-09 37.2 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGO26058.1 - 8.5e-08 32.1 6.4 2.6e-07 30.6 6.4 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGO26058.1 - 1.8e-05 24.7 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGO26058.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO26058.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HemY_N PF07219.13 EGO26058.1 - 0.53 10.5 2.3 0.81 9.9 0.9 2.2 2 0 0 2 2 2 0 HemY protein N-terminus TPR_10 PF13374.6 EGO26059.1 - 1.4e-128 415.8 28.6 1.4e-11 43.9 0.1 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 EGO26059.1 - 1.4e-108 355.4 37.6 3.2e-21 75.4 0.8 7.0 3 2 3 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGO26059.1 - 5.1e-46 151.4 23.6 0.00024 20.9 0.0 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26059.1 - 4.7e-44 146.5 32.3 0.00086 19.0 0.1 11.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26059.1 - 1.1e-34 115.7 26.7 0.011 15.8 0.2 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_8 PF13181.6 EGO26059.1 - 4.4e-26 88.9 29.6 0.11 12.8 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_19 PF14559.6 EGO26059.1 - 1.2e-20 73.8 15.7 0.0018 18.8 0.0 8.0 4 3 5 9 9 9 7 Tetratricopeptide repeat NB-ARC PF00931.22 EGO26059.1 - 2.5e-18 66.2 0.1 4.6e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.6 EGO26059.1 - 7.2e-18 65.0 30.9 0.02 15.5 0.7 10.6 9 2 0 9 9 9 5 Tetratricopeptide repeat PPR PF01535.20 EGO26059.1 - 4.1e-17 61.2 17.2 0.083 13.2 0.1 11.1 12 0 0 12 12 11 4 PPR repeat TPR_3 PF07720.12 EGO26059.1 - 6.6e-17 61.1 37.8 0.031 14.3 0.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO26059.1 - 5e-15 55.5 18.2 0.00061 20.0 2.9 7.0 2 1 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGO26059.1 - 5.9e-15 55.5 16.9 1.5e-09 37.7 7.4 3.8 1 1 3 4 4 4 4 MalT-like TPR region TPR_4 PF07721.14 EGO26059.1 - 1.5e-14 53.1 0.0 3.2 8.7 0.0 9.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO26059.1 - 8.7e-13 47.9 21.5 8.8 7.4 0.1 11.4 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO26059.1 - 9.4e-11 41.6 29.1 3.9 8.3 0.2 11.0 11 0 0 11 11 10 1 Tetratricopeptide repeat BAG PF02179.16 EGO26059.1 - 1.2e-10 41.6 0.0 2.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 BAG domain TPR_17 PF13431.6 EGO26059.1 - 2.4e-08 33.8 23.2 1 9.9 0.0 9.7 10 0 0 10 10 9 3 Tetratricopeptide repeat AAA_16 PF13191.6 EGO26059.1 - 1.3e-05 25.7 0.0 2.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain TPR_20 PF14561.6 EGO26059.1 - 0.0003 21.1 4.7 12 6.3 0.0 7.4 6 2 1 8 8 7 0 Tetratricopeptide repeat PPR_2 PF13041.6 EGO26059.1 - 0.00039 20.6 16.0 3.4 7.9 0.0 8.7 12 0 0 12 12 9 2 PPR repeat family ubiquitin PF00240.23 EGO26059.1 - 0.00054 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF4919 PF16266.5 EGO26059.1 - 0.00061 19.8 1.8 41 4.0 0.0 6.1 2 2 6 8 8 8 0 Domain of unknown function (DUF4919) CutA1 PF03091.15 EGO26059.1 - 0.0019 18.0 4.0 24 4.9 0.1 5.6 4 1 2 6 6 6 0 CutA1 divalent ion tolerance protein PPR_1 PF12854.7 EGO26059.1 - 0.011 15.4 7.6 2.8 7.7 1.2 5.8 6 0 0 6 6 5 0 PPR repeat RuvB_N PF05496.12 EGO26059.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RPN7 PF10602.9 EGO26059.1 - 0.027 14.2 13.0 22 4.7 0.1 7.4 6 2 2 8 8 8 0 26S proteasome subunit RPN7 RPN6_N PF18055.1 EGO26059.1 - 0.064 13.6 4.0 29 5.1 0.0 5.1 1 1 6 8 8 8 0 26S proteasome regulatory subunit RPN6 N-terminal domain Tcf25 PF04910.14 EGO26059.1 - 0.078 12.0 0.2 2.5 7.1 0.1 2.7 2 0 0 2 2 2 0 Transcriptional repressor TCF25 TPR_11 PF13414.6 EGO26059.1 - 0.12 12.1 42.9 5.2 6.9 0.3 10.2 11 0 0 11 11 10 0 TPR repeat COesterase PF00135.28 EGO26061.1 - 5.1e-77 259.9 0.0 7.4e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO26061.1 - 1e-08 35.3 0.2 5.4e-08 32.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO26061.1 - 0.0075 15.8 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S24 PF00717.23 EGO26062.1 - 7.8e-09 35.4 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGO26062.1 - 0.03 14.1 0.0 0.34 10.7 0.0 2.2 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 SRP_TPR_like PF17004.5 EGO26064.1 - 1.1e-14 54.4 1.1 1.7e-14 53.8 1.1 1.2 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 EGO26064.1 - 1.5e-08 35.0 0.7 4.2e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EGO26064.1 - 2e-05 24.8 2.7 0.0051 17.0 0.3 2.3 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGO26064.1 - 5.4e-05 23.0 2.6 0.42 10.8 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO26064.1 - 0.00032 20.7 0.2 0.32 11.1 0.0 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGO26064.1 - 0.00089 19.7 1.9 25 5.5 0.0 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO26064.1 - 0.012 15.9 3.0 0.13 12.6 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO26064.1 - 0.018 15.1 0.5 2.2 8.5 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26064.1 - 0.019 14.8 0.1 5 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGO26064.1 - 0.034 14.6 0.1 4.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 EGO26064.1 - 0.035 14.7 0.4 13 6.7 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGO26064.1 - 0.04 13.6 0.6 0.058 13.1 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.6 EGO26064.1 - 0.045 14.6 2.5 17 6.6 0.1 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 EGO26064.1 - 0.13 12.5 0.3 0.22 11.8 0.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Pinin_SDK_memA PF04696.13 EGO26065.1 - 6.9e-13 48.8 11.1 6.9e-13 48.8 11.1 3.4 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region ORC5_C PF14630.6 EGO26065.1 - 0.39 10.2 7.1 1.6 8.2 1.6 2.1 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Cellulase PF00150.18 EGO26066.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TEA PF01285.18 EGO26067.1 - 5.1e-12 45.7 0.1 1.5e-11 44.2 0.2 1.7 2 0 0 2 2 2 1 TEA/ATTS domain Dynamin_N PF00350.23 EGO26069.1 - 8.6e-24 84.5 0.0 2.2e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGO26069.1 - 1.5e-11 44.1 0.1 8.1e-10 38.4 0.1 2.8 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EGO26069.1 - 2.2e-09 37.3 0.2 2.4e-07 30.8 0.1 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_16 PF13191.6 EGO26069.1 - 7.7e-05 23.1 1.2 0.071 13.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGO26069.1 - 0.00069 19.7 0.0 0.0036 17.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGO26069.1 - 0.047 13.4 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO26069.1 - 0.11 13.0 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter LisH_TPL PF17814.1 EGO26069.1 - 0.15 11.8 0.6 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 LisH-like dimerisation domain AAA_23 PF13476.6 EGO26069.1 - 2 8.9 0.0 2 8.9 0.0 3.2 2 1 1 3 3 3 0 AAA domain WH1 PF00568.23 EGO26070.1 - 0.065 13.2 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 WH1 domain YL1 PF05764.13 EGO26073.1 - 0.0019 18.3 12.1 0.0033 17.6 12.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SR-25 PF10500.9 EGO26073.1 - 0.0045 16.6 9.1 0.0078 15.9 9.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein eIF3_subunit PF08597.10 EGO26073.1 - 0.011 15.7 10.9 0.011 15.7 10.9 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SRP14 PF02290.15 EGO26073.1 - 0.06 13.7 5.7 0.057 13.8 2.1 2.6 3 1 0 3 3 3 0 Signal recognition particle 14kD protein Myb_DNA-bind_2 PF08914.11 EGO26073.1 - 0.062 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Rap1 Myb domain CDC45 PF02724.14 EGO26073.1 - 0.096 11.0 9.1 0.14 10.4 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGO26073.1 - 0.2 11.0 13.4 0.3 10.4 13.4 1.3 1 0 0 1 1 1 0 BUD22 Dynamin_N PF00350.23 EGO26074.1 - 6.3e-29 101.2 0.0 1.2e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGO26074.1 - 9.7e-27 93.9 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 EGO26074.1 - 3.9e-12 46.2 0.0 2.6e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO26074.1 - 8.9e-05 22.6 0.0 0.00037 20.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO26074.1 - 0.0013 19.1 0.1 0.0055 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGO26074.1 - 0.0088 15.8 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO26074.1 - 0.023 15.2 0.2 0.45 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO26074.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 EGO26074.1 - 0.15 11.8 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EGO26075.1 - 1.9e-27 96.4 0.0 4.8e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGO26075.1 - 8.4e-24 84.3 0.0 1.3e-22 80.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EGO26075.1 - 3.5e-12 46.3 0.2 4.4e-11 42.8 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO26075.1 - 0.00019 21.5 0.0 0.00063 19.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGO26075.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO26075.1 - 0.013 15.9 0.5 0.05 14.0 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 EGO26075.1 - 0.11 12.3 0.1 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO26075.1 - 0.17 12.4 4.0 0.81 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF4428 PF14471.6 EGO26077.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) RdRP_5 PF07925.11 EGO26077.1 - 0.08 10.3 0.0 0.095 10.1 0.0 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 AAA_12 PF13087.6 EGO26078.1 - 1.1e-42 145.9 0.0 1.3e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGO26078.1 - 5.2e-06 26.2 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EGO26078.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGO26078.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CTK3 PF12243.8 EGO26079.1 - 1.3e-35 122.1 0.0 1.2e-34 119.0 0.0 2.0 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EGO26079.1 - 1.2e-25 89.4 4.1 2.4e-25 88.4 4.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF3437 PF11919.8 EGO26079.1 - 0.082 12.8 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) P66_CC PF16563.5 EGO26079.1 - 8.8 6.0 8.6 0.14 11.7 1.3 1.7 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 DRIM PF07539.12 EGO26080.1 - 1.9e-184 614.5 2.4 1.9e-184 614.5 2.4 4.1 3 1 1 4 4 4 2 Down-regulated in metastasis MMS19_N PF14500.6 EGO26080.1 - 0.0021 17.7 3.6 0.0045 16.6 1.3 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 EGO26080.1 - 0.0023 18.1 1.4 59 4.3 0.1 6.1 5 0 0 5 5 5 0 HEAT repeat Lin0512_fam PF09585.10 EGO26080.1 - 0.088 12.9 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) CoA_transf_3 PF02515.17 EGO26081.1 - 5.1e-105 351.6 0.0 6.2e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF1479 PF07350.12 EGO26082.1 - 6.5e-143 476.5 0.0 7.4e-143 476.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Ceramidase_alk PF04734.13 EGO26083.1 - 4.3e-217 721.8 0.0 5.1e-217 721.5 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGO26083.1 - 5.1e-57 192.4 0.2 9.2e-57 191.6 0.2 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Lactonase PF10282.9 EGO26084.1 - 2.5e-56 191.4 0.0 3.1e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Aminotran_5 PF00266.19 EGO26085.1 - 1.2e-39 136.4 0.0 1.7e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGO26085.1 - 0.031 13.5 0.0 0.052 12.7 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II CDH-cyt PF16010.5 EGO26090.1 - 0.013 15.2 0.2 0.018 14.7 0.2 1.3 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase AbiJ_NTD5 PF18865.1 EGO26090.1 - 0.084 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Zap1_zf2 PF18217.1 EGO26090.1 - 1.6 8.8 8.5 0.63 10.1 0.4 2.9 2 1 0 2 2 2 0 Zap1 zinc finger 2 Cauli_VI PF01693.16 EGO26091.1 - 1.7e-05 25.0 0.0 2.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Alpha_kinase PF02816.18 EGO26093.1 - 0.01 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-kinase family VCBS PF13517.6 EGO26094.1 - 8.1e-09 35.9 15.2 0.0012 19.4 0.6 5.0 1 1 4 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 EGO26094.1 - 8.4e-05 21.9 0.5 9 6.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGO26094.1 - 0.0077 16.1 7.1 26 5.1 0.1 4.4 4 0 0 4 4 4 0 EF-hand domain zf-UBP PF02148.19 EGO26094.1 - 0.012 15.9 0.0 1.7e+02 2.6 0.0 5.0 6 0 0 6 6 6 0 Zn-finger in ubiquitin-hydrolases and other protein KorB_C PF06613.11 EGO26094.1 - 0.014 15.4 0.3 55 3.8 0.0 4.3 5 0 0 5 5 5 0 KorB C-terminal beta-barrel domain DUF4374 PF14298.6 EGO26094.1 - 0.016 14.1 1.3 14 4.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4374) EF-hand_1 PF00036.32 EGO26094.1 - 0.053 13.1 3.8 46 3.9 0.0 4.1 4 0 0 4 4 4 0 EF hand DUF2436 PF10365.9 EGO26094.1 - 0.13 12.0 1.2 37 4.0 0.0 3.8 3 2 2 5 5 5 0 Domain of unknown function (DUF2436) Smoothelin PF12510.8 EGO26095.1 - 0.33 11.0 0.2 0.33 11.0 0.2 1.9 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein SPC25 PF06703.11 EGO26096.1 - 1 9.1 3.9 1.5 8.6 3.9 1.4 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Acyl-CoA_dh_2 PF08028.11 EGO26099.1 - 0.22 11.8 0.2 0.36 11.1 0.2 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain FG-GAP PF01839.23 EGO26100.1 - 0.0022 18.1 13.6 66 3.8 0.0 7.9 9 0 0 9 9 9 0 FG-GAP repeat Ribosomal_S28e PF01200.18 EGO26100.1 - 0.0033 17.4 1.2 2.6e+02 1.7 0.0 6.6 10 0 0 10 10 10 0 Ribosomal protein S28e zf-C2H2 PF00096.26 EGO26100.1 - 0.0059 17.0 0.3 1.2 9.7 0.0 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO26100.1 - 0.11 13.4 1.6 1.1 10.2 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger HET PF06985.11 EGO26104.1 - 0.13 12.6 0.3 0.47 10.8 0.0 1.8 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) Peptidase_M28 PF04389.17 EGO26106.1 - 4e-35 121.3 0.0 6.5e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGO26106.1 - 0.0054 15.8 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EGO26106.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF5056 PF16479.5 EGO26108.1 - 0.12 12.6 1.3 0.25 11.6 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) DUF1765 PF08578.10 EGO26108.1 - 0.7 10.4 7.8 3.6 8.1 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) ABC_tran PF00005.27 EGO26109.1 - 2.4e-26 92.9 0.0 3.9e-14 53.3 0.0 3.6 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EGO26109.1 - 5.5e-07 29.7 0.6 0.014 15.2 0.1 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGO26109.1 - 0.00017 21.8 0.0 0.48 10.7 0.0 2.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGO26109.1 - 0.0096 15.6 0.2 0.037 13.8 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF3584 PF12128.8 EGO26109.1 - 0.056 11.0 0.1 0.08 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.12 EGO26109.1 - 0.097 12.6 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Ploopntkinase1 PF18748.1 EGO26109.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 EF-hand_6 PF13405.6 EGO26111.1 - 4.6e-21 72.9 0.7 2.3e-05 24.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGO26111.1 - 1.2e-20 71.4 1.6 4.2e-05 22.8 0.1 4.7 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO26111.1 - 6.7e-19 68.1 1.5 4.7e-08 33.4 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGO26111.1 - 5e-16 57.4 0.3 7.2e-05 22.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGO26111.1 - 4.3e-13 48.9 3.6 8e-06 25.6 0.1 4.5 3 2 1 4 4 4 4 EF-hand domain pair Bromodomain PF00439.25 EGO26112.1 - 2.8e-23 81.8 0.7 1.4e-22 79.5 0.3 2.2 1 1 1 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EGO26112.1 - 0.00017 21.5 0.1 0.00032 20.6 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.32 EGO26113.1 - 5.1e-18 65.1 13.8 0.00025 21.8 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26113.1 - 8.8e-14 51.6 2.3 3.4e-05 24.1 0.1 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO26113.1 - 4.1e-05 23.6 0.2 0.0091 15.9 0.2 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EGO26113.1 - 0.0057 16.0 0.0 0.15 11.4 0.0 2.5 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EGO26113.1 - 0.065 12.2 0.0 0.5 9.3 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sugar_tr PF00083.24 EGO26116.1 - 7.6e-107 358.0 9.9 9.9e-107 357.6 9.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO26116.1 - 5.8e-24 84.7 33.8 7.4e-20 71.2 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO26116.1 - 0.0065 14.9 0.9 0.01 14.3 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RANK_CRD_2 PF18278.1 EGO26116.1 - 0.2 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 RRM_1 PF00076.22 EGO26117.1 - 8.5e-30 102.4 2.5 1.2e-08 34.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO26117.1 - 0.00072 19.6 0.0 2.2 8.4 0.1 2.7 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 EGO26117.1 - 0.0011 18.5 0.0 0.23 11.1 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO26117.1 - 0.0037 17.1 0.0 14 5.6 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif NID PF07292.13 EGO26117.1 - 0.006 17.2 0.0 12 6.6 0.0 3.5 4 0 0 4 4 4 1 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 EGO26117.1 - 0.15 12.2 0.0 2.8 8.1 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif zf_UBZ PF18439.1 EGO26118.1 - 0.04 13.5 0.7 0.085 12.5 0.7 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger FlhC PF05280.11 EGO26118.1 - 0.091 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Phage_int_SAM_5 PF13102.6 EGO26119.1 - 0.013 15.8 1.6 0.047 14.0 0.1 2.3 2 0 0 2 2 2 0 Phage integrase SAM-like domain Response_reg PF00072.24 EGO26120.1 - 4.2e-12 46.2 0.0 7.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain zf-CCHC PF00098.23 EGO26122.1 - 4.4e-05 23.4 5.0 4.4e-05 23.4 5.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO26122.1 - 0.00024 21.0 4.0 0.0006 19.7 4.0 1.7 1 0 0 1 1 1 1 Zinc knuckle M64_N PF16217.5 EGO26122.1 - 0.0074 15.9 0.4 0.04 13.5 0.2 2.3 2 1 1 3 3 3 1 Peptidase M64 N-terminus zf-CCHC PF00098.23 EGO26123.1 - 7e-06 25.9 2.1 1.6e-05 24.7 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26123.1 - 0.0095 16.2 1.5 0.022 15.0 0.4 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO26123.1 - 0.23 11.5 4.9 0.48 10.4 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle gag_pre-integrs PF13976.6 EGO26124.1 - 8.3e-10 38.4 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Metallophos PF00149.28 EGO26127.1 - 5.5e-16 59.7 3.7 8.6e-16 59.0 3.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EGO26127.1 - 0.0084 16.3 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain zf-C2H2_4 PF13894.6 EGO26128.1 - 0.01 16.6 4.6 5.6 8.1 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO26128.1 - 0.13 12.8 3.6 5 7.8 0.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 EGO26128.1 - 0.17 11.5 3.3 2.7 7.6 0.0 3.1 1 1 2 3 3 3 0 Zinc-finger C2H2-type zf_C2H2_13 PF18508.1 EGO26128.1 - 1.4 8.6 5.2 0.51 10.0 0.2 2.6 3 0 0 3 3 3 0 Zinc finger domain zf-C2H2_3rep PF18868.1 EGO26128.1 - 1.9 9.2 4.3 0.77 10.4 0.4 2.3 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats CutA1 PF03091.15 EGO26130.1 - 0.088 12.7 0.5 1.9 8.4 0.1 2.0 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Clat_adaptor_s PF01217.20 EGO26131.1 - 2.4e-18 66.5 0.0 3.7e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Bac_rhodopsin PF01036.18 EGO26132.1 - 1.7e-49 168.4 18.3 2.4e-49 167.9 18.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3810 PF12725.7 EGO26132.1 - 1.5 8.1 8.3 3.4 6.9 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2892 PF11127.8 EGO26132.1 - 2 8.5 8.4 3.7 7.6 4.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Arteri_Gl PF00951.18 EGO26132.1 - 3.3 7.5 8.3 0.23 11.2 2.8 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein zf-CHY PF05495.12 EGO26133.1 - 1.4e-13 51.1 18.5 2.4e-13 50.4 18.5 1.3 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 EGO26133.1 - 0.018 14.9 4.3 2.8 7.8 0.0 2.4 1 1 1 2 2 2 0 Cysteine-rich KTR Zn-ribbon_8 PF09723.10 EGO26133.1 - 0.039 14.1 4.4 0.039 14.1 4.4 2.7 1 1 2 3 3 3 0 Zinc ribbon domain zf-UDP PF14569.6 EGO26133.1 - 0.08 13.1 5.4 0.08 13.1 4.2 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger OSTMP1 PF09777.9 EGO26133.1 - 0.092 12.1 5.8 0.12 11.8 5.8 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DpnI PF06044.12 EGO26133.1 - 0.24 11.0 4.3 0.69 9.5 3.9 1.8 1 1 0 1 1 1 0 Dam-replacing family HypA PF01155.19 EGO26133.1 - 0.62 10.1 10.2 3.3 7.8 10.2 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 EGO26133.1 - 0.92 9.5 10.9 0.27 11.2 0.6 2.9 2 1 1 3 3 3 0 SprT-like zinc ribbon domain LIM PF00412.22 EGO26133.1 - 4.7 7.5 15.0 9.3 6.6 11.1 2.4 1 1 1 2 2 2 0 LIM domain zinc_ribbon_4 PF13717.6 EGO26133.1 - 7.7 6.5 14.4 3.1 7.8 0.8 3.5 3 0 0 3 3 3 0 zinc-ribbon domain rve PF00665.26 EGO26135.1 - 2.7e-05 24.3 0.0 0.00072 19.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO26135.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3527 PF12043.8 EGO26137.1 - 0.0011 18.6 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) BUD22 PF09073.10 EGO26139.1 - 0.0048 16.3 10.7 0.0069 15.8 10.7 1.3 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 EGO26139.1 - 0.0078 16.4 13.7 0.0078 16.4 13.7 1.4 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 EGO26139.1 - 0.045 12.0 6.1 0.044 12.1 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 EGO26139.1 - 0.049 13.2 9.8 0.083 12.5 9.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mit_KHE1 PF10173.9 EGO26139.1 - 0.16 12.0 1.4 0.29 11.2 1.4 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DNA_pol_phi PF04931.13 EGO26139.1 - 2.9 5.9 14.5 4.6 5.2 14.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EGO26139.1 - 4.2 6.3 9.4 1.3 8.1 6.7 1.5 2 0 0 2 2 2 0 Pes-10 Retrotrans_gag PF03732.17 EGO26140.1 - 7e-05 23.0 0.7 0.0001 22.5 0.7 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 EGO26140.1 - 0.11 12.6 0.3 16 5.7 0.1 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain RhoGEF PF00621.20 EGO26141.1 - 4.5e-33 115.0 0.0 1.4e-32 113.4 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain FAD_binding_4 PF01565.23 EGO26142.1 - 3.2e-11 43.1 0.3 1.4e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 EGO26142.1 - 7.5e-08 32.4 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGO26142.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.14 EGO26142.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Uso1_p115_head PF04869.14 EGO26144.1 - 3e-44 151.4 0.0 2.3e-42 145.2 0.0 3.1 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EGO26144.1 - 3.9e-13 49.9 24.9 3.9e-13 49.9 24.9 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3361 PF11841.8 EGO26144.1 - 0.00056 19.9 0.6 3.8 7.4 0.0 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3361) DUF3818 PF12825.7 EGO26144.1 - 0.022 13.8 6.8 0.031 13.3 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Mo25 PF08569.11 EGO26144.1 - 0.042 13.2 0.0 0.042 13.2 0.0 2.4 2 0 0 2 2 2 0 Mo25-like YabA PF06156.13 EGO26144.1 - 0.41 11.3 7.4 1.3 9.7 7.4 1.8 1 1 0 1 1 1 0 Initiation control protein YabA OmpH PF03938.14 EGO26144.1 - 0.52 10.6 9.2 1.1 9.6 9.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 EGO26144.1 - 2.5 8.6 5.4 6.8 7.2 3.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 EGO26144.1 - 4.3 7.2 11.2 1.1 9.1 5.9 2.4 1 1 1 2 2 2 0 Septum formation initiator NifQ PF04891.12 EGO26144.1 - 4.8 7.5 7.0 25 5.2 3.4 2.4 2 0 0 2 2 2 0 NifQ Aminotran_5 PF00266.19 EGO26145.1 - 9.6e-06 24.8 0.0 1e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V E1-E2_ATPase PF00122.20 EGO26146.1 - 1.1e-49 168.5 0.4 1.1e-49 168.5 0.4 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO26146.1 - 2e-36 125.4 0.2 2e-36 125.4 0.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO26146.1 - 4.6e-20 72.8 1.2 1.1e-18 68.3 1.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO26146.1 - 3.7e-11 42.9 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGO26146.1 - 2.9e-08 33.3 0.0 9e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO26146.1 - 0.00015 21.6 2.2 0.0014 18.5 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 EGO26146.1 - 0.0029 17.5 0.0 0.0029 17.5 0.0 2.7 4 0 0 4 4 4 1 Positive regulator of sigma(E), RseC/MucC HAD PF12710.7 EGO26146.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TrbC PF04956.13 EGO26146.1 - 3.6 7.9 15.5 4.9 7.4 1.6 4.0 3 0 0 3 3 3 0 TrbC/VIRB2 family BAF250_C PF12031.8 EGO26147.1 - 0.0068 15.7 0.1 0.1 11.8 0.2 2.5 2 1 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa Sacchrp_dh_NADP PF03435.18 EGO26148.1 - 5e-16 59.1 0.0 8.1e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGO26148.1 - 6e-06 26.3 0.0 9.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO26148.1 - 6.6e-05 22.6 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EGO26148.1 - 0.00018 21.9 0.0 0.0011 19.5 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGO26148.1 - 0.0023 17.5 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGO26148.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 EGO26148.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EGO26148.1 - 0.03 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EGO26148.1 - 0.036 14.1 0.0 3.9 7.5 0.1 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 EGO26149.1 - 3.8e-47 160.9 0.1 1.4e-46 159.0 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Adeno_E3_14_5 PF04834.12 EGO26150.1 - 0.058 13.9 0.9 0.065 13.8 0.9 1.2 1 0 0 1 1 1 0 Early E3 14.5 kDa protein ATP-synt_D PF01813.17 EGO26151.1 - 0.015 15.1 0.1 0.04 13.7 0.2 1.6 2 0 0 2 2 2 0 ATP synthase subunit D OEP PF02321.18 EGO26151.1 - 0.055 13.3 2.6 0.13 12.0 2.6 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein Ank_4 PF13637.6 EGO26153.1 - 2.4e-10 40.7 0.1 7.8e-05 23.2 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO26153.1 - 4e-09 36.6 0.7 9.6e-07 29.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO26153.1 - 5.1e-08 32.6 0.0 0.018 15.6 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGO26153.1 - 9.6e-07 29.3 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO26153.1 - 0.00084 19.7 0.3 2.7 8.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat MotA_activ PF09114.10 EGO26153.1 - 0.086 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription factor MotA, activation domain PseudoU_synth_2 PF00849.22 EGO26154.1 - 7.4e-29 100.9 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase p450 PF00067.22 EGO26156.1 - 3e-72 243.9 0.0 9.1e-72 242.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Fascin PF06268.13 EGO26157.1 - 0.00045 20.4 0.0 0.00074 19.7 0.0 1.3 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.12 EGO26157.1 - 0.018 14.8 0.1 3.7 7.2 0.0 2.0 1 1 1 2 2 2 0 FRG1-like domain Ank_2 PF12796.7 EGO26161.1 - 2.8e-05 24.6 0.0 4.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO26161.1 - 5.9e-05 23.2 0.1 0.0038 17.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGO26161.1 - 0.00031 21.2 0.1 0.0015 19.1 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO26161.1 - 0.00068 20.0 1.3 0.002 18.5 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGO26161.1 - 0.0038 17.5 0.0 0.0093 16.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Keratin_2_head PF16208.5 EGO26162.1 - 0.13 12.4 8.5 0.28 11.3 8.5 1.6 1 0 0 1 1 1 0 Keratin type II head VCBS PF13517.6 EGO26165.1 - 5.9e-13 49.2 23.9 0.00028 21.4 0.4 5.4 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 EGO26165.1 - 2e-06 27.0 4.0 3.8 7.2 0.0 5.5 6 0 0 6 6 6 4 EF hand EF-hand_1 PF00036.32 EGO26165.1 - 0.013 15.0 5.5 39 4.1 0.0 5.1 5 0 0 5 5 5 0 EF hand EF-hand_6 PF13405.6 EGO26165.1 - 0.073 13.0 14.0 21 5.4 0.1 5.9 6 0 0 6 6 6 0 EF-hand domain Aldo_ket_red PF00248.21 EGO26166.1 - 1.5e-38 132.7 0.0 3.9e-38 131.3 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family HyaE PF07449.11 EGO26166.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Peripla_BP_6 PF13458.6 EGO26166.1 - 0.057 13.1 0.1 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Periplasmic binding protein Abhydrolase_6 PF12697.7 EGO26167.1 - 3.2e-16 60.6 0.1 4.1e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.22 EGO26167.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DPBB_1 PF03330.18 EGO26173.1 - 1.2e-08 35.1 0.2 3.2e-08 33.8 0.2 1.8 1 1 0 1 1 1 1 Lytic transglycolase F-box-like PF12937.7 EGO26174.1 - 0.012 15.5 0.3 0.29 11.1 0.0 2.8 2 1 0 2 2 2 0 F-box-like DNA_pol_phi PF04931.13 EGO26174.1 - 5.2 5.0 7.7 7.7 4.5 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cytochrom_C PF00034.21 EGO26175.1 - 1.9e-09 38.6 0.0 2.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGO26175.1 - 3.8e-07 30.3 0.3 1.5e-06 28.4 0.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGO26175.1 - 0.021 14.5 0.2 0.13 11.9 0.0 2.0 2 1 0 2 2 2 0 Cytochrome c-550 domain p450 PF00067.22 EGO26176.1 - 1.7e-76 257.8 0.0 4.1e-76 256.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 EGO26177.1 - 5.6e-45 154.1 26.8 4.4e-23 82.3 9.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGO26177.1 - 1.5e-42 145.3 0.0 8.8e-30 104.0 0.0 2.9 2 1 0 2 2 2 2 ABC transporter T2SSE PF00437.20 EGO26177.1 - 2.4e-07 30.1 0.1 0.0047 16.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 EGO26177.1 - 5.9e-07 29.6 0.6 0.18 11.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO26177.1 - 3.3e-05 23.5 0.4 0.37 10.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO26177.1 - 3.8e-05 24.1 0.2 0.14 12.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EGO26177.1 - 4.8e-05 22.9 6.1 0.003 17.0 0.3 3.5 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EGO26177.1 - 4.8e-05 23.0 0.1 0.027 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGO26177.1 - 8.7e-05 23.1 0.0 0.061 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO26177.1 - 0.0049 17.1 0.4 17 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGO26177.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EGO26177.1 - 0.034 14.2 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGO26177.1 - 0.052 12.9 1.0 11 5.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EGO26177.1 - 0.055 13.5 0.0 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family PhoH PF02562.16 EGO26177.1 - 0.065 12.7 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 EGO26177.1 - 0.079 12.9 0.0 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGO26177.1 - 0.081 12.4 0.1 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGO26177.1 - 0.092 12.9 1.0 17 5.6 0.3 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGO26177.1 - 0.12 11.5 0.1 0.74 8.9 0.1 2.3 1 1 0 1 1 1 0 NB-ARC domain cobW PF02492.19 EGO26177.1 - 0.14 11.7 0.2 3 7.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGO26177.1 - 0.21 10.8 0.1 26 4.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Aldo_ket_red PF00248.21 EGO26178.1 - 1.1e-35 123.3 0.0 3e-35 121.8 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family HyaE PF07449.11 EGO26178.1 - 0.00027 20.9 0.1 0.00045 20.2 0.1 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE TUG-UBL1 PF11470.8 EGO26178.1 - 0.082 13.1 0.6 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 TUG ubiquitin-like domain Peptidase_M18 PF02127.15 EGO26179.1 - 5.8e-156 519.6 0.0 6.5e-156 519.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGO26179.1 - 0.016 14.2 0.0 0.18 10.8 0.1 2.2 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase AMP-binding PF00501.28 EGO26180.1 - 4.9e-66 223.1 0.0 5.8e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO26180.1 - 2.1e-09 38.3 0.2 1.1e-08 36.0 0.2 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_trans_aux PF03886.13 EGO26180.1 - 0.0026 17.4 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 ABC-type transport auxiliary lipoprotein component Gcn1_N PF12074.8 EGO26182.1 - 1.7e-93 313.8 0.7 1.7e-93 313.8 0.7 3.6 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 EGO26182.1 - 2.6e-27 94.9 20.2 0.00065 20.1 0.0 15.4 16 2 2 18 18 17 5 HEAT-like repeat HEAT PF02985.22 EGO26182.1 - 6.3e-25 85.1 16.7 0.15 12.4 0.0 16.8 19 0 0 19 19 18 6 HEAT repeat HEAT_2 PF13646.6 EGO26182.1 - 1.4e-22 79.9 27.3 7.3e-05 23.1 0.0 13.3 12 2 2 14 14 14 6 HEAT repeats Cnd1 PF12717.7 EGO26182.1 - 1.5e-09 38.1 0.0 5.9 6.9 0.0 7.7 4 1 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO26182.1 - 2e-08 34.1 0.0 0.0049 16.5 0.0 6.0 4 2 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EGO26182.1 - 2.8e-06 27.8 0.0 6.2 7.5 0.0 7.1 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region DUF3437 PF11919.8 EGO26182.1 - 0.00024 20.9 0.8 0.94 9.4 0.0 5.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 EGO26182.1 - 0.02 15.1 0.2 32 4.7 0.0 6.4 8 0 0 8 8 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 EGO26182.1 - 0.024 15.0 0.1 3.2 8.1 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 EGO26182.1 - 0.058 12.0 6.6 3.9 5.9 0.3 6.1 6 2 1 7 7 7 0 Adaptin N terminal region APC_u15 PF16636.5 EGO26182.1 - 0.13 12.7 0.4 0.4 11.2 0.4 1.8 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 NIF PF03031.18 EGO26184.1 - 9.8e-39 132.6 0.1 1.8e-38 131.8 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1180 PF06679.12 EGO26184.1 - 0.18 12.2 1.2 0.44 10.9 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NAD_binding_5 PF07994.12 EGO26185.1 - 7.1e-137 456.1 0.0 8.5e-137 455.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGO26185.1 - 5.7e-45 152.1 0.0 9.9e-45 151.3 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase UTP15_C PF09384.10 EGO26185.1 - 0.13 11.9 0.1 3.3 7.4 0.1 2.3 2 0 0 2 2 2 0 UTP15 C terminal EF-hand_like PF09279.11 EGO26186.1 - 0.073 13.6 0.2 0.18 12.3 0.2 1.6 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Sec34 PF04136.15 EGO26188.1 - 0.014 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Sec34-like family Sugarporin_N PF11471.8 EGO26188.1 - 0.025 14.5 1.8 0.056 13.4 0.1 2.3 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension XhlA PF10779.9 EGO26188.1 - 0.043 14.0 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA HSBP1 PF06825.12 EGO26188.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 FAA_hydro_N_2 PF18288.1 EGO26188.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 FTA4 PF13093.6 EGO26188.1 - 0.17 11.7 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Y_phosphatase3 PF13350.6 EGO26189.1 - 1.3e-59 202.0 0.0 1.5e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGO26189.1 - 0.0084 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGO26189.1 - 0.054 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGO26189.1 - 0.097 12.2 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family zf-H2C2_2 PF13465.6 EGO26190.1 - 0.015 15.7 2.1 0.088 13.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DM PF00751.18 EGO26190.1 - 0.078 12.9 9.8 0.31 11.0 0.4 2.8 3 0 0 3 3 3 0 DM DNA binding domain zf-C2H2_4 PF13894.6 EGO26190.1 - 0.36 11.8 8.0 10 7.2 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO26190.1 - 0.61 10.6 0.3 0.61 10.6 0.3 3.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type RhoGAP PF00620.27 EGO26191.1 - 5.1e-14 52.4 0.0 3.2e-13 49.8 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain Fmp27_WPPW PF10359.9 EGO26191.1 - 0.44 9.3 4.4 0.71 8.6 4.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CFEM PF05730.11 EGO26192.1 - 8.8e-10 38.5 13.9 1.5e-09 37.8 13.9 1.3 1 0 0 1 1 1 1 CFEM domain Pam17 PF08566.10 EGO26192.1 - 1.4 8.7 3.2 0.78 9.6 0.4 1.8 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 G-alpha PF00503.20 EGO26194.1 - 1.9e-116 389.1 2.0 2.2e-116 388.9 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO26194.1 - 6.2e-15 55.1 0.5 1.2e-09 37.9 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO26194.1 - 0.00071 19.0 0.4 0.37 10.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO26194.1 - 0.0061 16.8 0.2 0.79 10.0 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGO26194.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HEAT_EZ PF13513.6 EGO26195.1 - 1.9e-21 76.1 15.7 2.4e-09 37.5 0.1 8.7 8 1 1 9 9 9 3 HEAT-like repeat Importin_rep_4 PF18808.1 EGO26195.1 - 1.3e-18 67.1 0.9 6.1e-18 64.9 0.1 2.7 3 0 0 3 3 2 1 Importin repeat HEAT PF02985.22 EGO26195.1 - 3e-14 51.9 8.6 0.00011 22.2 0.0 8.6 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EGO26195.1 - 1.3e-11 44.7 7.2 0.00074 19.9 0.0 6.4 3 2 3 6 6 6 5 HEAT repeats RIX1 PF08167.12 EGO26195.1 - 5.1e-10 39.4 4.2 5.3e-06 26.3 0.0 4.1 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EGO26195.1 - 3.4e-08 34.0 0.3 0.00023 21.7 0.0 4.0 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGO26195.1 - 6.4e-05 23.0 0.6 0.0017 18.4 0.0 3.4 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EGO26195.1 - 0.00051 20.0 0.0 3.7 7.4 0.0 4.0 3 1 0 4 4 4 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 EGO26195.1 - 0.00063 18.4 0.3 0.0038 15.9 0.1 2.4 3 0 0 3 3 3 1 Adaptin N terminal region MMS19_C PF12460.8 EGO26195.1 - 0.0032 16.6 0.2 0.0032 16.6 0.2 3.3 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal TFCD_C PF12612.8 EGO26195.1 - 0.014 15.3 0.1 6.1 6.6 0.1 3.0 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal Cnd3 PF12719.7 EGO26195.1 - 0.021 14.0 2.1 6.8 5.8 0.0 4.2 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EGO26195.1 - 0.063 13.5 0.3 49 4.1 0.0 3.7 2 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3328 PF11807.8 EGO26196.1 - 6.9e-17 62.0 5.0 6.9e-17 62.0 5.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Acetyltransf_10 PF13673.7 EGO26197.1 - 2.6e-10 40.3 0.0 4.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO26197.1 - 2.2e-09 37.5 0.0 3.8e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO26197.1 - 8.3e-08 32.5 0.0 3.7e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO26197.1 - 4.2e-05 23.6 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO26197.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGO26197.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGO26197.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ But2 PF09792.9 EGO26198.1 - 0.00026 21.4 0.0 0.00052 20.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain BTP PF05232.12 EGO26199.1 - 0.18 11.9 2.0 1.5 8.9 0.6 2.0 1 1 1 2 2 2 0 Chlorhexidine efflux transporter zf-MYND PF01753.18 EGO26200.1 - 3.7e-10 39.7 16.4 7.4e-10 38.7 16.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO26200.1 - 9.5 6.6 13.2 19 5.6 13.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Retrotrans_gag PF03732.17 EGO26204.1 - 5.1e-06 26.7 2.6 9.7e-06 25.8 0.0 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO26204.1 - 0.02 15.0 3.8 0.043 13.9 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3328 PF11807.8 EGO26207.1 - 1e-14 54.8 3.0 1.5e-14 54.3 3.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) ABC2_membrane PF01061.24 EGO26209.1 - 1e-80 270.1 67.6 1.5e-42 145.4 24.7 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EGO26209.1 - 3.6e-36 124.7 0.0 2.2e-17 63.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGO26209.1 - 4e-31 106.8 3.9 6.4e-26 90.1 0.2 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGO26209.1 - 7.1e-09 36.2 0.0 2.2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EGO26209.1 - 1.2e-07 32.3 0.1 0.0011 19.4 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO26209.1 - 6.2e-07 29.5 0.1 3.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGO26209.1 - 3e-06 27.6 0.3 0.11 12.7 0.3 3.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGO26209.1 - 3.3e-05 24.1 0.1 0.029 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGO26209.1 - 6.5e-05 22.6 0.1 0.0064 16.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGO26209.1 - 0.00035 20.3 0.4 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 EGO26209.1 - 0.00068 19.6 0.3 0.13 12.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 EGO26209.1 - 0.00074 19.6 0.0 0.75 9.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EGO26209.1 - 0.00076 20.0 0.0 0.81 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGO26209.1 - 0.0011 18.2 23.6 0.0011 18.2 23.6 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_17 PF13207.6 EGO26209.1 - 0.0015 19.0 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EGO26209.1 - 0.002 18.0 1.5 0.71 9.6 0.0 3.1 4 0 0 4 4 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EGO26209.1 - 0.0024 18.1 0.3 0.48 10.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EGO26209.1 - 0.0046 16.8 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase PDR_assoc PF08370.11 EGO26209.1 - 0.0076 16.0 0.4 0.0076 16.0 0.4 4.0 4 0 0 4 4 3 1 Plant PDR ABC transporter associated cobW PF02492.19 EGO26209.1 - 0.015 14.9 0.9 1 8.9 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGO26209.1 - 0.017 14.9 0.2 1.2 8.8 0.3 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGO26209.1 - 0.033 13.6 0.0 1.3 8.4 0.0 3.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EGO26209.1 - 0.068 13.1 0.0 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 EGO26209.1 - 0.069 13.2 0.7 0.18 11.8 0.2 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EGO26209.1 - 0.085 13.1 0.0 15 5.9 0.0 2.9 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EGO26209.1 - 0.086 13.2 0.0 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EGO26209.1 - 0.12 12.8 0.4 5 7.6 0.1 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO26209.1 - 0.12 12.3 0.0 6.5 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Phage_holin_2_1 PF04971.12 EGO26209.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.6 2 0 0 2 2 1 0 Bacteriophage P21 holin S AAA_23 PF13476.6 EGO26209.1 - 0.14 12.7 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGO26209.1 - 0.15 11.8 0.5 5.7 6.7 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGO26209.1 - 0.25 10.6 0.1 6.1 6.0 0.1 2.2 2 0 0 2 2 2 0 Septin ABC2_membrane_2 PF12679.7 EGO26209.1 - 4.7 6.4 19.1 0.36 10.1 10.0 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Oxidored_FMN PF00724.20 EGO26212.1 - 3.3e-75 253.5 0.0 3.9e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 EGO26212.1 - 0.0014 18.3 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) Oxidored_FMN PF00724.20 EGO26213.1 - 2.9e-68 230.7 0.0 3.6e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 EGO26213.1 - 0.02 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) EIF_2_alpha PF07541.12 EGO26214.1 - 0.093 12.8 1.6 0.14 12.3 1.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit zf-3CxxC PF13695.6 EGO26214.1 - 0.77 10.3 7.0 1.3 9.6 7.0 1.6 1 1 0 1 1 1 0 Zinc-binding domain DUF1664 PF07889.12 EGO26214.1 - 0.9 9.6 5.9 3.3 7.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 EGO26214.1 - 1.2 9.6 5.8 2.5 8.5 1.3 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF5560 PF17715.1 EGO26215.1 - 1.8 8.0 6.5 5.2 6.5 6.5 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5560) RNA_pol_A_bac PF01000.26 EGO26217.1 - 9.7e-23 80.7 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGO26217.1 - 2.3e-16 59.0 0.0 3.6e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain VirE1 PF12189.8 EGO26218.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Single-strand DNA-binding protein MFS_1 PF07690.16 EGO26219.1 - 1.9e-36 125.7 33.3 8.1e-36 123.7 33.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO26219.1 - 5.6e-11 42.0 16.3 8.3e-10 38.1 4.1 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGO26219.1 - 9.1e-11 40.9 14.9 1.2e-10 40.5 14.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EGO26220.1 - 0.024 13.6 12.5 0.022 13.7 10.9 1.6 2 0 0 2 2 2 0 Major Facilitator Superfamily tRNA-synt_2 PF00152.20 EGO26222.1 - 2.8e-86 289.4 0.0 4.1e-86 288.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO26222.1 - 2.1e-10 40.4 0.1 5.6e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Evr1_Alr PF04777.13 EGO26223.1 - 1.2e-19 70.6 0.0 1.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family CAP59_mtransfer PF11735.8 EGO26224.1 - 9.1e-67 225.2 0.0 1.2e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Steroid_dh PF02544.16 EGO26225.1 - 7e-27 94.2 4.7 2.3e-14 53.6 0.4 3.2 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGO26225.1 - 0.00014 21.4 1.1 0.00032 20.3 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF739 PF05339.11 EGO26226.1 - 0.0059 16.7 0.1 0.76 10.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF739) STE3 PF02076.15 EGO26228.1 - 4.8e-98 327.9 16.7 5.6e-98 327.7 16.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor InaF-motif PF15018.6 EGO26232.1 - 4.7 7.2 8.5 1.1 9.1 4.0 2.3 2 0 0 2 2 2 0 TRP-interacting helix MgtE PF01769.16 EGO26232.1 - 6.6 7.1 12.8 5.2 7.5 3.9 2.3 2 0 0 2 2 2 0 Divalent cation transporter 2-Hacid_dh_C PF02826.19 EGO26233.1 - 1.1e-52 178.0 0.0 1.4e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO26233.1 - 1.8e-16 60.0 0.0 2.3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO26233.1 - 9.8e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EGO26233.1 - 0.0082 15.5 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 EGO26233.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ank_4 PF13637.6 EGO26234.1 - 0.00054 20.5 2.0 0.24 12.0 0.1 4.8 4 1 3 7 7 7 2 Ankyrin repeats (many copies) TetR_C_22 PF17928.1 EGO26234.1 - 0.12 12.7 1.0 5.4 7.4 0.2 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Dimer_Tnp_hAT PF05699.14 EGO26234.1 - 0.45 10.4 8.0 6.5 6.6 0.1 4.8 4 1 1 5 5 5 0 hAT family C-terminal dimerisation region PIN_8 PF18476.1 EGO26234.1 - 5.3 6.8 10.8 2.7 7.8 8.4 1.7 1 1 0 1 1 1 0 PIN like domain SesA PF17107.5 EGO26234.1 - 6.1 7.1 11.0 1.8 8.8 6.7 2.2 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sel1 PF08238.12 EGO26236.1 - 7.2e-25 86.9 43.1 9.3e-06 26.1 1.0 9.3 8 2 0 8 8 8 6 Sel1 repeat Utp13 PF08625.11 EGO26236.1 - 0.031 14.2 0.0 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain TPR_2 PF07719.17 EGO26236.1 - 0.13 12.4 0.0 0.13 12.4 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO26236.1 - 0.14 12.8 19.2 0.16 12.6 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO26236.1 - 1 10.2 11.9 28 5.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26236.1 - 1.5 8.8 11.1 15 5.6 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO26236.1 - 8.3 7.5 14.6 10 7.3 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat PPTA PF01239.22 EGO26237.1 - 1.5e-14 53.2 7.9 2.9e-06 26.8 0.6 5.4 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat RNase_T PF00929.24 EGO26238.1 - 1.4e-28 100.5 0.0 1.6e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EGO26238.1 - 0.00081 19.4 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like GREB1 PF15782.5 EGO26241.1 - 2.6 5.0 9.6 3 4.8 9.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FXR_C1 PF16096.5 EGO26242.1 - 0.018 15.2 0.9 0.018 15.2 0.9 3.1 2 1 1 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 Transposase_20 PF02371.16 EGO26242.1 - 0.21 11.9 0.3 0.21 11.9 0.3 1.7 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family DUF1917 PF08939.10 EGO26244.1 - 7.3e-25 88.4 0.3 7.3e-25 88.4 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) Fcf1 PF04900.12 EGO26246.1 - 1.4e-38 131.3 1.8 2.4e-38 130.5 1.8 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EGO26246.1 - 4.9e-11 43.0 0.1 1.6e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 PIN like domain Lyase_aromatic PF00221.19 EGO26247.1 - 1.8e-134 448.9 5.9 2.5e-134 448.5 5.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase CPSase_L_D2 PF02786.17 EGO26248.1 - 4.9e-101 336.6 0.0 2e-76 256.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EGO26248.1 - 5.3e-40 136.6 0.7 1.2e-39 135.4 0.7 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EGO26248.1 - 4.7e-16 58.8 0.0 9.1e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGO26248.1 - 7.5e-12 45.2 0.4 6.4e-05 22.6 0.1 2.6 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGO26248.1 - 6.1e-08 32.5 0.0 0.0011 18.7 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EGO26248.1 - 9.6e-07 28.5 0.1 0.0079 15.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EGO26248.1 - 0.0043 16.7 0.0 3.1 7.3 0.0 2.6 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EGO26248.1 - 0.0068 16.5 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 EGO26248.1 - 0.049 13.8 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 0 MGS-like domain Peptidase_M17_N PF02789.17 EGO26248.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF957 PF06117.11 EGO26249.1 - 0.18 11.4 0.0 0.59 9.7 0.0 1.8 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) Serglycin PF04360.12 EGO26251.1 - 0.00017 21.5 0.2 0.00034 20.6 0.2 1.4 1 0 0 1 1 1 1 Serglycin Transglut_core3 PF13471.6 EGO26251.1 - 0.022 14.7 0.4 0.053 13.4 0.4 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily SAP PF02037.27 EGO26251.1 - 0.058 13.2 1.1 0.25 11.2 0.6 2.4 2 0 0 2 2 2 0 SAP domain Lzipper-MIP1 PF14389.6 EGO26251.1 - 0.074 13.4 0.1 1.5 9.2 0.4 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Ashwin PF15323.6 EGO26251.1 - 0.077 13.0 5.2 0.11 12.5 5.2 1.2 1 0 0 1 1 1 0 Developmental protein WXG100 PF06013.12 EGO26251.1 - 0.25 11.6 1.6 0.28 11.5 0.2 1.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Pox_RNA_Pol_19 PF05320.12 EGO26251.1 - 2.8 7.9 5.3 30 4.6 5.3 2.0 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CCD48 PF15799.5 EGO26251.1 - 6.1 5.0 9.9 1.4 7.1 0.8 2.1 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 48 Abhydrolase_6 PF12697.7 EGO26253.1 - 3.5e-05 24.5 0.1 6.6e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_49 PF13896.6 EGO26254.1 - 1.1e-66 225.5 5.3 1.1e-51 176.1 0.4 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Alg14 PF08660.11 EGO26254.1 - 0.011 15.7 0.0 0.98 9.3 0.0 2.3 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Ceramidase PF05875.12 EGO26256.1 - 0.53 9.7 9.4 1.7 8.0 9.4 1.7 1 1 0 1 1 1 0 Ceramidase DUF4233 PF14017.6 EGO26256.1 - 1.2 9.5 8.4 0.53 10.6 5.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) TMEM220 PF15071.6 EGO26257.1 - 0.027 15.2 2.5 0.082 13.7 0.4 2.2 2 1 0 2 2 2 0 Transmembrane family 220, helix Rer1 PF03248.13 EGO26259.1 - 1.5e-78 262.4 0.6 1.8e-78 262.2 0.6 1.0 1 0 0 1 1 1 1 Rer1 family AAA_5 PF07728.14 EGO26260.1 - 0.0093 16.0 0.1 0.097 12.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO26260.1 - 0.019 15.3 0.0 0.052 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EGO26260.1 - 0.022 14.9 0.2 0.045 13.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGO26260.1 - 0.036 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 EGO26260.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGO26260.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGO26260.1 - 0.26 11.0 0.0 0.41 10.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CIAPIN1 PF05093.13 EGO26263.1 - 0.28 11.7 1.1 0.35 11.4 1.1 1.5 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Acetyltransf_1 PF00583.25 EGO26264.1 - 4.7e-07 30.1 0.0 6.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO26264.1 - 8.5e-05 22.5 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGO26264.1 - 9.9e-05 22.7 0.0 0.00018 21.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO26264.1 - 0.01 16.5 0.0 0.014 16.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 EGO26268.1 - 1.2e-08 35.5 0.1 3.8e-08 33.9 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO26268.1 - 0.023 15.0 0.3 0.11 12.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGO26268.1 - 0.039 13.9 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EGO26268.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGO26268.1 - 0.061 12.9 0.3 0.51 9.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain RNA12 PF10443.9 EGO26268.1 - 0.2 10.4 0.2 13 4.4 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein zf-CCCH_2 PF14608.6 EGO26269.1 - 6.3e-11 42.3 38.9 9.9e-05 22.7 2.8 4.6 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger TraT PF05818.12 EGO26269.1 - 0.14 11.9 0.0 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Cyt-b5 PF00173.28 EGO26272.1 - 4.2e-16 58.8 0.0 5e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IHO1 PF15771.5 EGO26274.1 - 0.061 12.1 4.2 0.06 12.1 4.2 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 zf-CCHC PF00098.23 EGO26275.1 - 8.4e-08 32.0 1.2 1.2e-07 31.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO26275.1 - 0.0087 15.6 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCHC_6 PF15288.6 EGO26275.1 - 0.13 12.1 1.5 0.22 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DIRP PF06584.13 EGO26278.1 - 0.059 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 DIRP GPI-anchored PF10342.9 EGO26279.1 - 0.006 17.3 0.1 0.0083 16.9 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tim17 PF02466.19 EGO26281.1 - 4.7e-33 113.9 9.8 5.7e-33 113.6 9.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABA_WDS PF02496.16 EGO26281.1 - 0.073 13.6 0.3 6.1 7.4 0.0 2.5 2 0 0 2 2 2 0 ABA/WDS induced protein Arrestin_N PF00339.29 EGO26282.1 - 9.9e-15 54.9 0.0 2.5e-09 37.4 0.0 3.5 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGO26282.1 - 5.6e-13 49.5 0.0 1.2e-11 45.2 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Cauli_VI PF01693.16 EGO26286.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin SOBP PF15279.6 EGO26287.1 - 0.28 11.8 4.3 0.35 11.4 4.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2883 PF11097.8 EGO26288.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) VHL PF01847.16 EGO26290.1 - 1e-10 41.3 0.1 1.4e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 VHL beta domain MethyltransfD12 PF02086.15 EGO26293.1 - 0.23 11.1 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TssO PF17561.2 EGO26294.1 - 0.12 12.4 0.1 0.16 12.1 0.1 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssO F-box-like PF12937.7 EGO26295.1 - 0.0054 16.6 2.7 0.0069 16.3 0.6 2.3 2 0 0 2 2 2 1 F-box-like Amidohydro_1 PF01979.20 EGO26296.1 - 3.9e-21 75.8 0.0 6.9e-16 58.5 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EGO26296.1 - 8.6e-11 42.0 0.0 3.5e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidase PF01425.21 EGO26297.1 - 2.7e-87 293.6 0.0 5.2e-87 292.7 0.0 1.5 1 1 0 1 1 1 1 Amidase DUF4772 PF15997.5 EGO26299.1 - 0.13 12.9 0.0 0.18 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) NMO PF03060.15 EGO26302.1 - 3.6e-35 121.9 4.1 9.4e-23 81.1 0.8 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EGO26302.1 - 3.8e-12 45.9 0.1 9.5e-07 28.1 0.0 2.3 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO26302.1 - 2e-09 36.9 0.4 6.1e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EGO26302.1 - 4.4e-05 22.8 0.0 5.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EGO26302.1 - 0.0012 18.1 0.2 0.17 11.0 0.1 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase CPSase_L_D2 PF02786.17 EGO26302.1 - 0.0037 16.8 0.5 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain NADH_oxidored PF08040.11 EGO26302.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 MNLL subunit His_biosynth PF00977.21 EGO26302.1 - 0.034 13.6 0.5 0.062 12.8 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein TRSP PF12500.8 EGO26302.1 - 0.17 11.8 0.7 0.38 10.7 0.0 1.9 3 0 0 3 3 3 0 TRSP domain C terminus to PRTase_2 Aminotran_1_2 PF00155.21 EGO26303.1 - 1.9e-37 129.3 0.0 3.4e-37 128.5 0.0 1.4 1 1 1 2 2 2 1 Aminotransferase class I and II p450 PF00067.22 EGO26304.1 - 3.5e-60 204.1 0.0 4.3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO26305.1 - 2.3e-85 287.1 0.0 2.6e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PQ-loop PF04193.14 EGO26306.1 - 7.1e-05 22.5 1.0 7.1e-05 22.5 1.0 3.9 4 1 0 4 4 4 2 PQ loop repeat Cas_GSU0054 PF09609.10 EGO26306.1 - 0.036 12.8 0.1 0.05 12.3 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF3533 PF12051.8 EGO26307.1 - 2.4e-70 237.4 20.1 3.1e-70 237.0 20.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Peripla_BP_6 PF13458.6 EGO26307.1 - 0.015 15.0 3.0 0.022 14.5 3.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein TRI5 PF06330.11 EGO26308.1 - 1.3e-07 30.9 0.1 0.024 13.5 0.0 3.0 2 1 1 3 3 3 3 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 EGO26308.1 - 0.029 13.7 0.1 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Oxidored_FMN PF00724.20 EGO26309.1 - 5.7e-71 239.5 0.0 6.8e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 EGO26309.1 - 0.012 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) p450 PF00067.22 EGO26310.1 - 1.6e-17 63.4 0.0 1.8e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO26311.1 - 5.2e-19 68.3 0.0 6.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.18 EGO26313.1 - 7e-29 101.0 0.0 9.7e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein OPT PF03169.15 EGO26315.1 - 1.1e-185 618.8 51.0 1.3e-185 618.6 51.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4097 PF13349.6 EGO26317.1 - 3.7e-05 23.2 0.3 6e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 Putative adhesin LEA_2 PF03168.13 EGO26317.1 - 0.055 14.0 0.0 0.33 11.5 0.0 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein LSM PF01423.22 EGO26318.1 - 1.4e-16 59.9 0.0 1.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain F-box-like PF12937.7 EGO26319.1 - 1.1e-06 28.5 5.0 0.00022 21.1 0.1 3.0 3 0 0 3 3 3 2 F-box-like Telomere_res PF16684.5 EGO26320.1 - 0.29 10.6 0.5 0.44 10.0 0.5 1.2 1 0 0 1 1 1 0 Telomere resolvase Pantoate_transf PF02548.15 EGO26322.1 - 2.5e-103 345.0 0.1 3e-103 344.7 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGO26322.1 - 1.5e-05 24.6 0.1 2.6e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase SnoaL_2 PF12680.7 EGO26323.1 - 2.2e-05 25.0 0.0 3.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGO26323.1 - 0.032 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EGO26324.1 - 0.0016 19.0 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Kri1 PF05178.12 EGO26325.1 - 6.9e-28 97.2 6.1 6.9e-28 97.2 6.1 6.4 6 2 1 7 7 7 1 KRI1-like family Kri1_C PF12936.7 EGO26325.1 - 1e-22 80.1 0.0 1e-22 80.1 0.0 5.0 4 0 0 4 4 4 1 KRI1-like family C-terminal LRR_8 PF13855.6 EGO26326.1 - 6.4e-05 22.6 8.5 0.00042 20.0 0.1 3.4 2 1 0 3 3 3 1 Leucine rich repeat LRRNT_2 PF08263.12 EGO26326.1 - 0.002 18.4 1.1 0.002 18.4 1.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Peptidase_C2 PF00648.21 EGO26327.1 - 1.3e-21 76.9 0.0 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGO26327.1 - 3.3e-14 53.3 0.0 0.00015 22.1 0.0 4.3 3 2 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 EGO26327.1 - 1.4e-05 25.0 0.3 2.6e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF2213 PF09979.9 EGO26327.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Rit1_C PF17184.4 EGO26328.1 - 2.1e-76 257.0 0.0 7.6e-52 176.4 0.0 2.6 1 1 1 2 2 2 2 Rit1 N-terminal domain Peptidase_C50 PF03568.17 EGO26328.1 - 0.013 14.6 0.2 0.024 13.7 0.2 1.5 1 0 0 1 1 1 0 Peptidase family C50 DUF3450 PF11932.8 EGO26328.1 - 0.014 14.7 5.8 0.03 13.6 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SKA2 PF16740.5 EGO26328.1 - 2.9 7.7 9.3 1.7 8.5 2.5 3.6 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF4203 PF13886.6 EGO26329.1 - 7.5e-17 61.7 23.7 7.5e-17 61.7 23.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Mito_carr PF00153.27 EGO26330.1 - 2.9e-66 219.4 1.9 5.8e-23 80.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FSH1 PF03959.13 EGO26331.1 - 5.5e-53 179.8 0.0 6.4e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EGO26331.1 - 0.01 15.5 0.0 0.39 10.3 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO26331.1 - 0.26 11.0 0.6 0.9 9.3 0.2 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGO26332.1 - 4.4e-34 118.0 0.0 6.5e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EGO26332.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HEAT_EZ PF13513.6 EGO26334.1 - 3.2e-29 101.0 20.8 5.2e-14 52.4 0.0 10.9 9 3 2 11 11 11 5 HEAT-like repeat HEAT PF02985.22 EGO26334.1 - 1.9e-16 58.7 17.2 0.00019 21.4 0.0 9.8 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EGO26334.1 - 3.3e-16 59.4 0.3 6.4e-06 26.5 0.0 7.2 6 2 0 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EGO26334.1 - 9.5e-10 38.9 0.1 0.016 15.8 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGO26334.1 - 4.6e-07 29.7 0.7 0.21 11.7 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGO26334.1 - 1.5e-06 28.3 0.2 0.29 11.2 0.0 4.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGO26334.1 - 0.00027 19.7 0.7 0.42 9.1 0.1 3.4 3 0 0 3 3 3 2 Adaptin N terminal region DUF3437 PF11919.8 EGO26334.1 - 0.0015 18.4 0.2 16 5.5 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) IBN_N PF03810.19 EGO26334.1 - 0.0036 17.2 0.0 0.097 12.6 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Tti2 PF10521.9 EGO26334.1 - 0.0053 16.3 0.2 3.9 6.9 0.1 3.6 2 2 2 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 EGO26334.1 - 0.015 15.5 0.3 0.33 11.1 0.0 3.2 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 EGO26334.1 - 0.14 12.5 0.4 1e+02 3.3 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Lectin_leg-like PF03388.13 EGO26335.1 - 1.5e-63 214.2 0.0 2e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 EGO26335.1 - 0.0033 17.0 0.0 0.93 9.0 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain ER_lumen_recept PF00810.18 EGO26336.1 - 2.9e-57 193.6 9.7 4.3e-57 193.1 9.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGO26336.1 - 0.00086 19.0 7.6 1.3 8.8 0.1 4.3 3 1 1 4 4 4 2 PQ loop repeat DnaJ PF00226.31 EGO26337.1 - 1.7e-11 44.1 0.0 2.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Homeobox_KN PF05920.11 EGO26338.1 - 0.013 15.4 0.6 0.041 13.8 0.6 1.8 1 1 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 EGO26338.1 - 0.078 12.8 0.3 0.14 12.0 0.3 1.4 1 1 0 1 1 1 0 Homeodomain Pkinase PF00069.25 EGO26339.1 - 6e-69 232.3 0.0 7.2e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26339.1 - 7.4e-36 123.8 0.0 9.9e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO26339.1 - 0.07 12.5 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM110_C PF14160.6 EGO26340.1 - 0.021 15.9 1.0 0.05 14.7 0.8 2.0 1 1 1 2 2 2 0 Centrosome-associated C terminus SNF2_N PF00176.23 EGO26341.1 - 1e-62 211.9 0.5 1.6e-62 211.3 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO26341.1 - 7.5e-17 61.7 2.8 1.1e-15 57.9 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO26341.1 - 7.8e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO26341.1 - 0.00082 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pro-kuma_activ PF09286.11 EGO26342.1 - 1e-44 152.3 0.1 2.1e-44 151.3 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO26342.1 - 5.2e-07 29.2 12.7 5.3e-07 29.2 6.9 2.2 2 0 0 2 2 2 2 Subtilase family cEGF PF12662.7 EGO26343.1 - 0.0051 16.7 0.7 0.0051 16.7 0.7 2.6 3 0 0 3 3 3 1 Complement Clr-like EGF-like Pro-kuma_activ PF09286.11 EGO26344.1 - 6.7e-45 152.9 0.1 2.9e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO26344.1 - 0.0006 19.2 0.3 0.001 18.4 0.3 1.3 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 EGO26345.1 - 1.1e-46 158.7 0.5 5e-45 153.3 0.3 2.2 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Pro-kuma_activ PF09286.11 EGO26346.1 - 4.7e-42 143.6 0.4 4.9e-41 140.4 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO26346.1 - 1.8e-06 27.5 2.0 3.5e-06 26.5 2.0 1.5 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 EGO26347.1 - 2e-43 148.1 0.1 1e-42 145.8 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO26347.1 - 4.7e-07 29.4 0.2 7.9e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 Subtilase family Sulfate_transp PF00916.20 EGO26348.1 - 3e-85 286.2 12.5 3e-85 286.2 12.5 1.6 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 EGO26348.1 - 3.9e-18 65.2 0.0 6.6e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGO26348.1 - 4.3e-06 27.0 0.0 8.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain Peptidase_S8 PF00082.22 EGO26349.1 - 3.4e-34 118.5 9.1 5.6e-34 117.8 9.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGO26349.1 - 5.8e-15 55.7 0.3 1e-14 55.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Kinesin PF00225.23 EGO26350.1 - 4.1e-40 137.7 0.1 5.8e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Pro-kuma_activ PF09286.11 EGO26351.1 - 5.5e-47 159.6 1.4 8.6e-46 155.8 0.4 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Pro-kuma_activ PF09286.11 EGO26352.1 - 5.4e-42 143.5 0.1 2.4e-41 141.3 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO26352.1 - 1.1e-05 24.9 1.7 1.8e-05 24.1 1.7 1.3 1 0 0 1 1 1 1 Subtilase family zf-CCHC PF00098.23 EGO26354.1 - 4.5e-08 32.8 5.2 8.9e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26354.1 - 6.3e-07 29.6 0.1 6.3e-07 29.6 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO26354.1 - 0.018 15.0 1.9 0.018 15.0 1.9 2.0 2 0 0 2 2 2 0 Zinc knuckle Pro-kuma_activ PF09286.11 EGO26355.1 - 1.4e-42 145.4 0.1 5.9e-42 143.3 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO26355.1 - 3e-05 23.5 1.7 5.4e-05 22.6 1.7 1.3 1 0 0 1 1 1 1 Subtilase family Granulin PF00396.18 EGO26356.1 - 7.5 7.0 27.1 0.85 10.0 1.4 3.1 1 1 1 2 2 2 0 Granulin 3HCDH_N PF02737.18 EGO26359.1 - 9e-52 175.6 2.9 4.2e-51 173.4 2.9 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGO26359.1 - 4.6e-32 110.5 0.0 1.1e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGO26359.1 - 0.00016 21.9 0.9 0.00077 19.7 0.7 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGO26359.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EGO26359.1 - 0.29 11.7 4.3 4.2 8.0 2.7 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Cyclase PF04199.13 EGO26360.1 - 2.9e-34 118.2 0.3 3.8e-34 117.9 0.3 1.2 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_31 PF01055.26 EGO26362.1 - 1.1e-135 453.2 3.6 1.1e-135 453.2 3.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGO26362.1 - 9.3e-18 64.3 0.1 2.9e-17 62.7 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EGO26362.1 - 1.1e-06 28.9 0.0 3.3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gb3_synth PF04572.12 EGO26362.1 - 0.0028 17.9 0.1 0.0055 16.9 0.1 1.4 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region DUF4968 PF16338.5 EGO26362.1 - 0.061 13.6 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) NtCtMGAM_N PF16863.5 EGO26362.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Sin_N PF04801.13 EGO26363.1 - 2.4e-26 93.0 0.0 2.9e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Abhydrolase_3 PF07859.13 EGO26364.1 - 2.2e-21 76.7 0.0 3.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO26364.1 - 9.9e-06 24.6 0.0 1.4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase FcoT PF10862.8 EGO26365.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain Sld7_C PF18596.1 EGO26366.1 - 9.3e-07 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Sld7 C-terminal domain DUF3253 PF11625.8 EGO26366.1 - 0.045 14.0 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) polyprenyl_synt PF00348.17 EGO26372.1 - 9.6e-61 205.1 0.0 2.2e-32 112.1 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Efg1 PF10153.9 EGO26373.1 - 3.3e-13 50.0 2.9 3.3e-13 50.0 2.9 1.6 1 1 0 1 1 1 1 rRNA-processing protein Efg1 LytTR PF04397.15 EGO26373.1 - 0.061 13.6 0.1 0.094 12.9 0.0 1.5 1 1 0 1 1 1 0 LytTr DNA-binding domain ATP-synt_D PF01813.17 EGO26373.1 - 0.46 10.3 8.0 0.53 10.1 8.0 1.1 1 0 0 1 1 1 0 ATP synthase subunit D IKI3 PF04762.12 EGO26374.1 - 3e-229 763.6 0.3 9e-126 421.1 0.0 3.1 1 1 2 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 EGO26374.1 - 5.2e-06 26.7 1.0 4.5 7.7 0.0 6.3 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain DUF460 PF04312.13 EGO26374.1 - 0.0063 16.2 0.0 0.66 9.7 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF460) Ribosomal_S7 PF00177.21 EGO26374.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Clathrin PF00637.20 EGO26374.1 - 0.19 11.6 1.0 7.1 6.5 0.3 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF805 PF05656.14 EGO26375.1 - 8.2 6.9 10.5 6 7.3 7.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF805) MIF4G PF02854.19 EGO26376.1 - 6.2e-39 133.8 0.0 1.1e-38 133.0 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGO26376.1 - 7.5e-06 25.9 0.0 2e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 MA3 domain SesA PF17107.5 EGO26376.1 - 0.051 13.8 1.3 0.079 13.2 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TrkH PF02386.16 EGO26377.1 - 4.7e-103 345.3 14.7 1.4e-100 337.2 8.5 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.11 EGO26377.1 - 0.24 11.4 2.2 0.37 10.8 0.3 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein LCM PF04072.14 EGO26380.1 - 1e-23 84.3 0.0 2.6e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase FMN_dh PF01070.18 EGO26382.1 - 3.9e-120 401.0 0.0 4.8e-120 400.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGO26382.1 - 3.8e-20 71.8 0.0 9e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EGO26382.1 - 1.3e-05 24.4 0.1 3.1e-05 23.2 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGO26382.1 - 1.6e-05 24.2 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EGO26382.1 - 0.0023 17.3 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGO26382.1 - 0.04 13.4 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 EGO26382.1 - 0.06 12.7 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Salt_tol_Pase PF09506.10 EGO26382.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) PEP_mutase PF13714.6 EGO26383.1 - 4.4e-45 154.0 1.6 5.5e-45 153.7 1.6 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGO26383.1 - 1.1e-17 63.8 0.2 1.5e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family FMN_dh PF01070.18 EGO26384.1 - 7.8e-119 396.8 0.1 9.2e-119 396.5 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGO26384.1 - 1.4e-19 70.0 0.0 3.2e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGO26384.1 - 5.5e-05 22.5 0.0 8.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGO26384.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Retrotrans_gag PF03732.17 EGO26386.1 - 9.5e-08 32.2 0.3 3.9e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.11 EGO26387.1 - 6.1e-05 22.8 0.0 7.4e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO26387.1 - 7.4e-05 23.2 0.0 0.00011 22.7 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO26387.1 - 0.00065 20.3 0.1 0.00074 20.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 EGO26387.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease PAM2 PF07145.15 EGO26389.1 - 0.011 15.4 0.2 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Ataxin-2 C-terminal region DUF896 PF05979.12 EGO26389.1 - 0.029 14.2 2.9 0.029 14.2 2.9 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF896) UPF0242 PF06785.11 EGO26389.1 - 1.8 8.6 16.2 0.54 10.3 12.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus eIF_4G1 PF12152.8 EGO26390.1 - 1.1e-17 64.0 0.1 2.2e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 SBP56 PF05694.11 EGO26390.1 - 0.086 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) MIF4G PF02854.19 EGO26391.1 - 2e-34 119.1 0.0 3.1e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGO26391.1 - 4.2e-05 23.5 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 MA3 domain Costars PF14705.6 EGO26391.1 - 0.14 12.4 0.2 32 4.8 0.1 3.2 3 0 0 3 3 3 0 Costars DLIC PF05783.11 EGO26391.1 - 0.23 10.2 1.5 0.58 8.9 1.5 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Hydrophobin PF01185.18 EGO26392.1 - 3e-17 63.0 11.4 3.9e-17 62.7 11.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 EGO26392.1 - 2.4 8.9 7.4 10 6.9 0.2 2.7 4 0 0 4 4 4 0 Ion channel inhibitory toxin MIF4G PF02854.19 EGO26393.1 - 6.2e-89 297.2 11.6 2.6e-50 171.0 0.5 2.4 2 0 0 2 2 2 2 MIF4G domain eIF_4G1 PF12152.8 EGO26393.1 - 7.6e-14 51.7 0.1 1.8e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 EGO26393.1 - 6.8e-06 26.0 0.4 8.6e-05 22.5 0.0 2.9 3 0 0 3 3 3 1 MA3 domain GlutR_dimer PF00745.20 EGO26393.1 - 4.5 7.8 6.4 41 4.7 0.1 4.3 5 0 0 5 5 5 0 Glutamyl-tRNAGlu reductase, dimerisation domain HSP70 PF00012.20 EGO26396.1 - 9.6e-263 872.8 13.4 1.1e-262 872.6 13.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO26396.1 - 1.7e-15 56.7 4.4 5.7e-14 51.7 0.8 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 EGO26396.1 - 0.026 14.9 7.4 3.9 8.0 0.2 4.1 3 2 0 3 3 3 0 Cell division protein FtsA WD40 PF00400.32 EGO26397.1 - 1.7e-08 35.0 3.2 0.0001 23.0 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat APH PF01636.23 EGO26399.1 - 9.1e-41 140.3 0.0 1.3e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO26399.1 - 1.4e-08 34.6 0.0 2.1e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 EGO26399.1 - 9.5e-06 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RRXRR PF14239.6 EGO26399.1 - 0.052 13.4 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 RRXRR protein Pkinase PF00069.25 EGO26399.1 - 0.088 12.2 0.0 0.33 10.3 0.0 1.8 2 1 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EGO26399.1 - 0.23 10.3 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.17 EGO26400.1 - 7.9e-45 153.2 0.0 1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO26400.1 - 1.3e-36 126.4 0.0 1.6e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGO26400.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO26400.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 EGO26400.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Abhydrolase_3 PF07859.13 EGO26401.1 - 5.9e-22 78.6 0.4 1.7e-16 60.7 0.4 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO26401.1 - 0.0022 16.9 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase VEGFR-2_TMD PF17988.1 EGO26402.1 - 0.1 12.0 1.7 0.19 11.2 1.7 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain GST_N_3 PF13417.6 EGO26403.1 - 1.8e-16 60.3 0.0 3.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO26403.1 - 1.6e-15 57.2 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGO26403.1 - 5.5e-10 39.5 0.2 1.8e-09 37.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO26403.1 - 1.5e-06 28.3 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO26403.1 - 2.9e-05 24.0 0.0 5.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGO26403.1 - 0.0035 17.9 0.0 0.0055 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGO26403.1 - 0.11 13.3 0.2 0.25 12.1 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain adh_short PF00106.25 EGO26404.1 - 1.8e-29 102.6 0.8 4.1e-23 81.9 0.7 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO26404.1 - 3e-19 69.5 0.3 5.9e-18 65.3 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO26404.1 - 2.9e-08 33.8 0.3 4.2e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO26404.1 - 0.02 14.0 0.2 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Foie-gras_1 PF11817.8 EGO26405.1 - 4.4e-41 141.2 0.7 4.3e-39 134.7 0.9 3.0 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EGO26405.1 - 2.1e-10 40.0 0.0 6.7e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_12 PF13424.6 EGO26405.1 - 0.00047 20.4 4.1 0.00061 20.0 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TRAPPC10 PF12584.8 EGO26405.1 - 0.0029 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_10 PF13374.6 EGO26405.1 - 0.036 13.9 0.2 0.37 10.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26405.1 - 0.068 13.0 1.0 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26405.1 - 0.17 12.0 4.3 0.21 11.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO26405.1 - 0.18 11.9 0.9 1.2 9.3 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO26405.1 - 0.21 12.3 0.5 1 10.1 0.5 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat ubiquitin PF00240.23 EGO26409.1 - 6.6e-07 29.0 0.3 3.6e-06 26.6 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGO26409.1 - 1e-05 25.9 0.2 5.1e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain PI3K_rbd PF00794.18 EGO26409.1 - 0.0048 17.1 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain RAWUL PF16207.5 EGO26409.1 - 0.018 15.7 0.0 0.021 15.5 0.0 1.1 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 EGO26409.1 - 0.025 14.4 0.1 0.095 12.5 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 EGO26409.1 - 0.038 14.5 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RecQ5 PF06959.11 EGO26410.1 - 0.021 14.8 0.6 0.034 14.1 0.6 1.3 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) PhaP_Bmeg PF09602.10 EGO26410.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PIEZO PF15917.5 EGO26411.1 - 0.019 14.5 4.6 0.019 14.5 4.6 1.0 1 0 0 1 1 1 0 Piezo DUF1645 PF07816.11 EGO26411.1 - 1.2 9.6 8.5 1.5 9.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF3112 PF11309.8 EGO26412.1 - 0.062 12.7 8.8 0.72 9.3 6.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) GWT1 PF06423.12 EGO26412.1 - 9.9 6.3 11.7 3.4 7.8 5.7 2.5 1 1 1 2 2 2 0 GWT1 DUF2156 PF09924.9 EGO26414.1 - 1.7e-12 46.9 0.0 3.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2156) BORG_CEP PF14957.6 EGO26414.1 - 0.011 16.9 1.5 0.013 16.7 0.1 1.8 2 0 0 2 2 2 0 Cdc42 effector PROCN PF08083.11 EGO26417.1 - 0.032 13.0 0.4 0.04 12.6 0.4 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Herpes_UL6 PF01763.16 EGO26417.1 - 0.078 11.5 1.6 0.094 11.2 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like HIP1_clath_bdg PF16515.5 EGO26417.1 - 0.15 12.7 6.0 0.23 12.1 6.0 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_membrane PF00664.23 EGO26419.1 - 6.1e-48 163.8 0.2 9.3e-48 163.2 0.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGO26419.1 - 5.1e-30 104.8 0.0 1.5e-29 103.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGO26419.1 - 1.2e-05 24.8 0.1 0.00091 18.7 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EGO26419.1 - 0.0037 16.6 0.0 0.014 14.7 0.0 1.9 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EGO26419.1 - 0.054 13.9 0.2 0.25 11.7 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EGO26419.1 - 0.061 13.0 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 EGO26419.1 - 0.2 11.9 1.7 1.4 9.2 0.3 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PGP_phosphatase PF09419.10 EGO26420.1 - 1.9e-13 50.4 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Clathrin_lg_ch PF01086.17 EGO26421.1 - 6.3e-46 157.3 0.1 7.6e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Clathrin light chain Ribosomal_L30_N PF08079.12 EGO26421.1 - 2.5 8.4 9.0 4.3 7.7 9.0 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Hydrolase_4 PF12146.8 EGO26422.1 - 1.8e-55 187.8 0.0 2.1e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO26422.1 - 3.1e-17 63.9 0.1 4.1e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO26422.1 - 9e-07 28.8 1.0 4.6e-05 23.2 0.8 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO26422.1 - 0.0028 17.5 0.2 0.095 12.5 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGO26422.1 - 0.01 15.3 1.6 0.18 11.3 0.0 2.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family PhoPQ_related PF10142.9 EGO26422.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.12 EGO26422.1 - 0.15 10.7 0.1 1 8.0 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_28 PF00295.17 EGO26424.1 - 3.9e-60 203.6 10.2 5.1e-60 203.2 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2087 PF09860.9 EGO26426.1 - 0.029 14.5 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF4404 PF14357.6 EGO26426.1 - 0.11 13.2 2.7 4.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) BTB PF00651.31 EGO26427.1 - 1.1e-09 38.5 0.0 3.4e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EGO26428.1 - 4.2e-08 33.4 0.0 1e-07 32.2 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EGO26429.1 - 5.2e-07 29.9 0.0 8.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.9 EGO26430.1 - 1.7e-42 145.3 0.1 2.3e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BTB PF00651.31 EGO26431.1 - 6.2e-09 36.1 0.0 9.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BDV_M PF16520.5 EGO26431.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 ssRNA-binding matrix protein of Bornaviridae BTB PF00651.31 EGO26432.1 - 0.00017 21.8 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BDV_M PF16520.5 EGO26432.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 ssRNA-binding matrix protein of Bornaviridae SinI PF08671.10 EGO26432.1 - 0.95 9.3 3.6 0.32 10.8 0.5 1.9 2 0 0 2 2 2 0 Anti-repressor SinI BTB PF00651.31 EGO26433.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SUR7 PF06687.12 EGO26437.1 - 4.9e-05 23.1 10.8 0.16 11.6 9.2 2.4 1 1 1 2 2 2 2 SUR7/PalI family Flavi_capsid PF01003.19 EGO26437.1 - 0.093 12.5 0.8 0.13 12.0 0.8 1.2 1 0 0 1 1 1 0 Flavivirus capsid protein C RNase_T PF00929.24 EGO26440.1 - 1.8e-14 54.6 0.0 2.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGO26440.1 - 0.0089 15.7 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DUF5051 PF16473.5 EGO26440.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like Pox_A11 PF05061.13 EGO26440.1 - 0.37 10.0 1.9 0.6 9.3 0.1 2.1 3 0 0 3 3 3 0 Poxvirus A11 Protein Mito_carr PF00153.27 EGO26441.1 - 1.3e-44 150.0 1.6 1.3e-20 73.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 EGO26441.1 - 0.016 15.2 0.8 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Colicin V production protein MreB_Mbl PF06723.13 EGO26442.1 - 0.02 13.7 0.2 5.7 5.7 0.0 2.5 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 EGO26442.1 - 0.026 12.7 0.0 3.4 5.7 0.1 3.2 2 1 0 2 2 2 0 Hsp70 protein Peptidase_M22 PF00814.25 EGO26442.1 - 0.052 13.2 0.0 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Glycoprotease family Hydantoinase_A PF01968.18 EGO26442.1 - 0.11 11.7 0.1 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase KR PF08659.10 EGO26443.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGO26443.1 - 0.0035 16.8 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Cpn60_TCP1 PF00118.24 EGO26444.1 - 2e-146 488.5 1.4 2.3e-146 488.3 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 EGO26444.1 - 0.054 13.0 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 EAL domain Alpha_L_fucos PF01120.17 EGO26449.1 - 2.1e-79 267.5 2.6 2.4e-79 267.3 2.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase FYVE PF01363.21 EGO26450.1 - 0.034 14.3 0.7 0.087 13.0 0.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF3141 PF11339.8 EGO26451.1 - 0.68 8.3 1.5 0.72 8.2 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DDE_Tnp_4 PF13359.6 EGO26454.1 - 2.1e-30 105.5 0.0 2.6e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO26454.1 - 0.00012 21.8 0.1 0.00024 20.8 0.1 1.5 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 EGO26454.1 - 0.041 13.5 0.4 0.069 12.7 0.0 1.6 2 0 0 2 2 2 0 Plant transposon protein WD40 PF00400.32 EGO26456.1 - 6.2e-12 45.8 7.6 0.0013 19.5 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26456.1 - 2.4e-05 24.5 0.0 1.9 8.8 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO26456.1 - 0.00072 19.5 0.0 0.23 11.3 0.0 3.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A BCHF PF07284.11 EGO26456.1 - 0.14 12.2 5.3 0.25 11.3 5.3 1.4 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) MTCP1 PF08991.10 EGO26457.1 - 6e-20 71.2 7.7 7.2e-20 71.0 7.7 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type DUF1081 PF06448.11 EGO26457.1 - 0.036 14.5 0.8 0.036 14.5 0.8 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1081) CX9C PF16860.5 EGO26457.1 - 0.18 11.8 7.8 0.33 11.0 7.8 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ribosomal_L22e PF01776.17 EGO26458.1 - 9.3e-49 164.4 0.4 1.1e-48 164.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Glyco_hydro_16 PF00722.21 EGO26461.1 - 0.00016 21.2 0.0 0.00037 20.0 0.0 1.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 polyprenyl_synt PF00348.17 EGO26462.1 - 1.6e-61 207.6 0.0 1.9e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3611 PF12263.8 EGO26463.1 - 0.014 15.3 3.3 0.019 14.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) DUF2542 PF10808.8 EGO26463.1 - 0.083 13.4 1.1 0.083 13.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) B12D PF06522.11 EGO26463.1 - 0.13 12.1 0.4 0.51 10.2 0.0 2.1 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ubiquitin PF00240.23 EGO26464.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EGO26464.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO26464.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EGO26464.1 - 1.6e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO26464.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGO26464.1 - 1.7e-17 63.5 11.5 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 EGO26464.1 - 5.3e-16 59.1 2.2 0.55 10.8 0.0 5.2 1 1 0 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGO26464.1 - 3.1e-12 46.6 0.7 1.6 8.5 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 EGO26464.1 - 3.7e-09 36.3 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 EGO26464.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 EGO26464.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 EGO26464.1 - 1.9e-07 31.4 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 EGO26464.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 EGO26464.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EGO26464.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 EGO26464.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EGO26464.1 - 2.3e-05 23.9 0.1 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EGO26464.1 - 6e-05 23.6 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 EGO26464.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EGO26464.1 - 0.0007 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EGO26464.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EGO26464.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 EGO26464.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 EGO26464.1 - 0.46 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 EGO26464.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 EGO26464.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EGO26464.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 EGO26464.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e FA_desaturase PF00487.24 EGO26465.1 - 0.0087 15.9 1.3 0.0087 15.9 1.3 1.0 1 0 0 1 1 1 1 Fatty acid desaturase UPF0029 PF01205.19 EGO26467.1 - 1.7e-23 82.9 0.0 3.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 BORCS6 PF10157.9 EGO26467.1 - 0.0081 16.4 0.9 0.014 15.6 0.9 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 TERB2 PF15101.6 EGO26468.1 - 2.6 8.1 5.5 1.9 8.5 1.7 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DDA1 PF10172.9 EGO26469.1 - 0.0002 21.6 17.5 1.7e+02 2.5 0.0 10.4 11 0 0 11 11 11 4 Det1 complexing ubiquitin ligase FLILHELTA PF10306.9 EGO26470.1 - 5.5e-09 36.3 0.0 9.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EGO26470.1 - 0.0017 18.9 0.0 0.0025 18.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Acyl-CoA_dh_N PF02771.16 EGO26472.1 - 3.9e-27 95.2 0.0 6.6e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGO26472.1 - 1.4e-22 80.5 0.2 2.4e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO26472.1 - 1.3e-20 73.4 0.0 2.6e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO26472.1 - 0.00013 22.3 0.1 0.00028 21.2 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGO26472.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DNA_pol_B_palm PF14792.6 EGO26473.1 - 1.1e-20 74.0 0.1 3.7e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 EGO26473.1 - 3.8e-10 39.4 0.0 9.8e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGO26473.1 - 4.8e-10 39.7 0.1 8e-08 32.5 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 EGO26473.1 - 1.2e-06 28.6 0.0 9.7e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_5 PF14520.6 EGO26473.1 - 6.9e-05 23.4 0.0 0.0012 19.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 EGO26473.1 - 0.00033 20.8 0.0 0.00076 19.7 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus NTP_transf_2 PF01909.23 EGO26473.1 - 0.011 16.0 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.8 EGO26473.1 - 0.015 15.6 0.0 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif BRCT_2 PF16589.5 EGO26473.1 - 0.032 14.6 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DAGK_cat PF00781.24 EGO26473.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain bZIP_1 PF00170.21 EGO26474.1 - 2.5e-08 33.9 9.6 3.3e-08 33.5 8.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO26474.1 - 4.6e-06 26.6 9.0 4.6e-06 26.6 9.0 2.1 2 0 0 2 2 2 1 Basic region leucine zipper ABC_tran_CTD PF16326.5 EGO26474.1 - 0.00098 19.3 8.9 0.0031 17.7 7.9 2.0 1 1 1 2 2 2 2 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 EGO26474.1 - 0.046 13.7 5.7 0.067 13.2 5.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4349 PF14257.6 EGO26474.1 - 0.054 12.9 0.6 0.088 12.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1690 PF07956.11 EGO26474.1 - 0.39 11.1 6.2 0.64 10.4 6.2 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Seryl_tRNA_N PF02403.22 EGO26474.1 - 0.55 10.5 4.0 0.87 9.8 4.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CTP_transf_like PF01467.26 EGO26475.1 - 8.6e-23 81.1 0.0 1.1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF764 PF05561.11 EGO26475.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) Amidase PF01425.21 EGO26476.1 - 3.1e-82 277.0 0.0 1.9e-81 274.3 0.0 1.9 1 1 0 1 1 1 1 Amidase RSN1_7TM PF02714.15 EGO26478.1 - 5.5e-77 258.8 24.5 1e-76 257.8 24.5 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGO26478.1 - 1e-37 129.3 0.8 1e-37 129.3 0.8 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGO26478.1 - 4.6e-37 127.9 0.0 6.5e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Pkinase_fungal PF17667.1 EGO26481.1 - 3.5e-58 197.3 0.0 4.8e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO26481.1 - 8.5e-07 28.6 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26481.1 - 0.0012 18.1 0.0 0.0026 17.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase GH114_assoc PF14741.6 EGO26482.1 - 0.37 11.0 5.6 0.39 10.9 0.8 2.6 3 0 0 3 3 3 0 N-terminal glycosyl-hydrolase-114-associated domain ATG7_N PF16420.5 EGO26483.1 - 1.2e-93 314.0 0.0 1.6e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGO26483.1 - 4.9e-47 160.3 0.0 7.1e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family FGE-sulfatase PF03781.16 EGO26484.1 - 2.6e-23 83.0 0.3 3.1e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGO26484.1 - 1.3e-06 29.0 1.3 2.6e-06 28.0 1.3 1.5 1 0 0 1 1 1 1 DinB superfamily TatD_DNase PF01026.21 EGO26488.1 - 2e-25 89.7 0.0 2.7e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Met_10 PF02475.16 EGO26489.1 - 1.7e-64 217.3 0.0 4.7e-64 215.8 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EGO26489.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 EGO26489.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 EGO26489.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Pyridoxal_deC PF00282.19 EGO26490.1 - 5.1e-104 348.0 0.0 5.9e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain adh_short PF00106.25 EGO26491.1 - 6.2e-39 133.5 0.1 8.5e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO26491.1 - 4.4e-18 65.7 0.0 6.9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO26491.1 - 2e-06 27.8 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO26491.1 - 3.4e-06 26.6 0.1 5e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Golgin_A5 PF09787.9 EGO26492.1 - 0.099 12.1 24.6 1.1 8.6 24.6 2.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 BLOC1_2 PF10046.9 EGO26492.1 - 1 9.7 8.0 2.9 8.3 0.7 3.9 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.20 EGO26492.1 - 5.6 6.3 31.2 6.7 6.0 26.8 3.3 2 1 0 2 2 2 0 Tropomyosin DAO PF01266.24 EGO26493.1 - 1.3e-26 94.0 0.0 1.7e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO26493.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO26493.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO26493.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding F-box-like PF12937.7 EGO26494.1 - 3.9e-11 42.7 1.0 1.1e-10 41.2 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO26494.1 - 0.013 15.4 0.1 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 F-box domain zf-CCHC PF00098.23 EGO26497.1 - 3.1e-08 33.3 1.6 6.6e-08 32.3 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26497.1 - 4.4e-06 26.9 0.7 2.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO26497.1 - 0.28 11.2 2.8 0.63 10.0 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF563 PF04577.14 EGO26499.1 - 1.6e-20 74.2 0.1 3.4e-20 73.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) TPM_phosphatase PF04536.14 EGO26499.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 TPM domain MA3 PF02847.17 EGO26499.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 MA3 domain LCAT PF02450.15 EGO26500.1 - 4.2e-68 230.3 0.2 2.8e-33 115.7 0.3 3.0 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Trp_halogenase PF04820.14 EGO26501.1 - 1.1e-26 93.7 2.0 2.7e-15 56.2 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase FAD_binding_3 PF01494.19 EGO26501.1 - 1.2e-10 41.2 0.1 4.4e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGO26501.1 - 2.1e-05 24.6 0.7 7e-05 23.0 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO26501.1 - 4e-05 23.0 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO26501.1 - 0.00011 21.9 1.1 0.0065 16.1 0.8 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO26501.1 - 0.00012 21.6 2.8 0.00037 20.0 2.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO26501.1 - 0.0002 20.2 0.3 0.00036 19.4 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EGO26501.1 - 0.00032 19.9 0.1 0.00053 19.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGO26501.1 - 0.00054 19.2 0.8 0.00099 18.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO26501.1 - 0.0039 16.5 1.4 0.0073 15.6 0.1 2.0 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 EGO26501.1 - 0.0049 17.4 0.1 0.012 16.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO26501.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein TrbI PF03743.14 EGO26501.1 - 0.024 14.5 0.1 0.062 13.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Pyr_redox_3 PF13738.6 EGO26501.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EGO26503.1 - 1.4e-66 224.6 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26503.1 - 3.3e-29 102.0 0.0 4.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EGO26503.1 - 0.015 16.2 0.0 0.04 14.8 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Haspin_kinase PF12330.8 EGO26503.1 - 0.019 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGO26503.1 - 0.043 13.7 0.2 0.18 11.7 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGO26503.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fic PF02661.18 EGO26504.1 - 8.6e-11 42.6 0.0 1.3e-10 42.1 0.0 1.2 1 0 0 1 1 1 1 Fic/DOC family IGPS PF00218.21 EGO26506.1 - 1.8e-89 299.3 0.0 3.2e-89 298.4 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EGO26506.1 - 1.5e-42 145.5 0.0 4.6e-42 144.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.22 EGO26506.1 - 4e-41 140.9 0.1 7.1e-21 74.9 0.0 3.3 2 1 0 3 3 3 3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 EGO26506.1 - 8.4e-05 22.4 0.5 0.00044 20.1 0.5 2.0 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 EGO26506.1 - 0.00072 18.8 0.1 0.016 14.4 0.0 2.7 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.19 EGO26506.1 - 0.0021 17.8 0.3 0.014 15.2 0.1 2.4 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EGO26506.1 - 0.018 14.5 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 EGO26506.1 - 0.083 12.2 0.0 0.083 12.2 0.0 2.5 4 0 0 4 4 4 0 Thiazole biosynthesis protein ThiG PB1 PF00564.24 EGO26507.1 - 1.1e-13 50.9 0.0 2.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 EGO26507.1 - 2.6e-07 30.2 3.1 0.045 13.6 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26507.1 - 2.7e-07 30.2 0.9 0.11 12.7 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO26507.1 - 9.9e-06 25.4 0.8 0.016 15.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO26507.1 - 5.2e-05 23.5 0.6 0.014 15.7 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO26507.1 - 0.00064 19.4 0.1 0.0057 16.3 0.1 2.7 1 1 1 2 2 2 1 TPR repeat TPR_7 PF13176.6 EGO26507.1 - 0.4 10.8 2.2 20 5.5 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat G-patch PF01585.23 EGO26508.1 - 6.2e-07 29.2 0.2 6.2e-07 29.2 0.2 2.0 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 EGO26508.1 - 0.0051 16.9 0.2 0.0051 16.9 0.2 2.3 2 1 0 2 2 2 1 G-patch domain Abhydrolase_1 PF00561.20 EGO26509.1 - 1.6e-24 87.0 0.1 6.7e-24 84.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EGO26509.1 - 1.3e-21 75.9 0.1 2.5e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 EGO26509.1 - 0.0012 18.6 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGO26509.1 - 0.0021 17.4 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 EGO26511.1 - 2e-15 56.2 83.8 0.048 14.1 0.8 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO26511.1 - 1e-14 54.0 75.8 0.0075 17.0 1.4 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO26511.1 - 6e-09 35.9 70.1 7.7e-05 22.9 0.4 11.1 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 EGO26511.1 - 6.4e-06 26.4 36.9 0.0017 18.6 7.9 6.6 3 1 4 7 7 7 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EGO26511.1 - 0.0014 18.9 33.3 0.017 15.4 0.3 7.4 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGO26511.1 - 0.0067 16.4 0.7 0.0067 16.4 0.7 8.2 8 0 0 8 8 8 3 C2H2-type zinc finger zf-met PF12874.7 EGO26511.1 - 0.05 14.0 1.5 0.05 14.0 1.5 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type PcF PF09461.10 EGO26511.1 - 0.9 10.0 7.5 9.8 6.6 4.7 2.6 2 0 0 2 2 2 0 Phytotoxin PcF protein GAGA PF09237.11 EGO26511.1 - 5.2 7.0 13.9 4.3 7.2 0.1 4.4 3 1 1 4 4 4 0 GAGA factor Isochorismatase PF00857.20 EGO26512.1 - 1.2e-17 64.6 0.4 6.9e-13 49.2 0.2 2.0 2 0 0 2 2 2 2 Isochorismatase family PH PF00169.29 EGO26514.1 - 5.6e-06 26.8 0.0 1.5e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_12 PF16457.5 EGO26514.1 - 0.039 14.5 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain FOLN PF09289.10 EGO26514.1 - 0.19 11.9 0.2 0.43 10.8 0.2 1.6 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain STE3 PF02076.15 EGO26515.1 - 6.6e-07 28.8 3.5 8.2e-07 28.5 3.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor Adeno_PVIII PF01310.18 EGO26515.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII STE3 PF02076.15 EGO26516.1 - 1.6e-86 290.1 28.1 1.9e-86 289.9 28.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_M24 PF00557.24 EGO26517.1 - 6.8e-49 166.4 0.0 8.4e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGO26517.1 - 4.1e-20 71.8 7.2 6.7e-20 71.1 7.2 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGO26517.1 - 0.00018 21.5 3.5 0.00043 20.3 3.5 1.7 1 0 0 1 1 1 1 MYND finger STE3 PF02076.15 EGO26518.1 - 1.3e-88 297.0 17.4 1.5e-88 296.8 17.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Virul_fac_BrkB PF03631.15 EGO26518.1 - 0.021 14.4 0.3 0.021 14.4 0.3 2.6 3 0 0 3 3 3 0 Virulence factor BrkB DUF3671 PF12420.8 EGO26518.1 - 0.13 12.3 0.2 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2975 PF11188.8 EGO26518.1 - 6.2 6.7 9.3 1.8 8.4 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) ubiquitin PF00240.23 EGO26519.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EGO26519.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO26519.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EGO26519.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO26519.1 - 1.4e-14 54.2 7.5 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO26519.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO26519.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGO26519.1 - 5.3e-10 39.4 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGO26519.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EGO26519.1 - 5.1e-07 29.3 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EGO26519.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 EGO26519.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 EGO26519.1 - 5.6e-06 26.7 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EGO26519.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 EGO26519.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 EGO26519.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EGO26519.1 - 0.00034 20.1 0.0 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EGO26519.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 EGO26519.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EGO26519.1 - 0.007 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EGO26519.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EGO26519.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 EGO26519.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif DMA PF03474.14 EGO26519.1 - 0.28 10.8 4.0 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 DMRTA motif Phage_sheath_1N PF17481.2 EGO26519.1 - 0.44 11.0 9.2 46 4.6 1.3 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 EGO26519.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 EGO26519.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EGO26519.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein BRCT_2 PF16589.5 EGO26520.1 - 0.056 13.9 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Methyltransf_2 PF00891.18 EGO26529.1 - 2.9e-24 85.6 0.0 3.4e-22 78.8 0.0 2.2 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGO26529.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGO26529.1 - 0.013 16.2 0.0 0.036 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGO26529.1 - 0.042 14.6 0.0 0.087 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EGO26529.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein GidB PF02527.15 EGO26529.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G AAA_16 PF13191.6 EGO26530.1 - 1.6e-07 31.9 0.0 2.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGO26530.1 - 2.2e-06 27.7 0.2 7.6e-06 25.9 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EGO26530.1 - 3e-05 24.3 0.0 5.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGO26530.1 - 0.00054 19.6 0.0 0.0013 18.4 0.0 1.6 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 EGO26530.1 - 0.0036 16.5 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 EGO26530.1 - 0.0063 15.8 0.0 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EGO26530.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 KaiC AAA PF00004.29 EGO26530.1 - 0.012 16.0 0.1 0.041 14.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AA_permease_N PF08403.10 EGO26530.1 - 0.021 14.3 0.1 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 Amino acid permease N-terminal RNA_helicase PF00910.22 EGO26530.1 - 0.031 14.7 0.0 0.048 14.0 0.0 1.5 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGO26530.1 - 0.053 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EGO26530.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGO26530.1 - 0.083 13.4 0.3 0.25 11.9 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGO26530.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EGO26531.1 - 4.7e-12 46.3 0.9 3e-07 30.9 0.5 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGO26531.1 - 8.6e-12 44.9 1.9 8.3e-05 22.9 0.6 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGO26531.1 - 1.8e-08 34.5 3.7 0.0024 18.2 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO26531.1 - 5.8e-08 33.1 1.6 3.9e-05 24.1 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO26531.1 - 6.3e-07 29.2 3.3 0.0099 16.3 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeat KDZ PF18758.1 EGO26534.1 - 3e-05 23.7 0.2 3.8e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Med9 PF07544.13 EGO26535.1 - 0.015 15.4 2.3 0.021 14.9 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Retrotrans_gag PF03732.17 EGO26536.1 - 1.7e-08 34.6 0.4 1.7e-08 34.6 0.4 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO26536.1 - 0.00074 19.5 8.9 0.0014 18.6 8.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO26536.1 - 1.5 8.8 8.6 0.64 10.0 5.4 2.0 2 0 0 2 2 2 0 Zinc knuckle ICE2 PF08426.10 EGO26538.1 - 8.7e-28 97.6 25.8 1.7e-15 57.1 10.7 2.9 1 1 0 2 2 2 2 ICE2 MoaE PF02391.17 EGO26539.1 - 9.9e-38 128.9 0.0 1.2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 MoaE protein CHAT PF12770.7 EGO26540.1 - 2.4e-32 112.5 0.0 4.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EGO26540.1 - 4e-07 30.2 26.5 0.39 11.0 3.4 10.4 10 3 3 13 13 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO26540.1 - 9.4e-05 22.2 3.6 1 9.6 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO26540.1 - 0.0008 19.9 7.7 30 5.2 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26540.1 - 0.0017 18.1 10.0 0.4 10.6 0.2 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO26540.1 - 0.0019 17.8 1.6 2.2 8.1 0.0 5.1 6 0 0 6 6 6 1 TPR repeat TPR_8 PF13181.6 EGO26540.1 - 0.025 14.8 0.1 31 5.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26540.1 - 0.025 14.7 4.1 1.2e+02 3.2 0.2 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Transketolase_N PF00456.21 EGO26540.1 - 0.1 11.5 0.5 1.9 7.3 0.0 2.7 3 1 0 3 3 3 0 Transketolase, thiamine diphosphate binding domain TPR_10 PF13374.6 EGO26540.1 - 0.33 10.9 22.6 15 5.6 0.0 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat APH PF01636.23 EGO26541.1 - 1.2e-10 41.8 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO26541.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EGO26541.1 - 0.096 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase BcrAD_BadFG PF01869.20 EGO26542.1 - 1.2e-12 47.9 0.0 9.4e-12 45.0 0.0 2.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF2263 PF10021.9 EGO26543.1 - 2.3e-28 99.4 0.0 3.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Plavaka PF18759.1 EGO26546.1 - 9.4e-40 136.8 0.1 9.4e-40 136.8 0.1 2.1 2 0 0 2 2 2 1 Plavaka transposase FrhB_FdhB_C PF04432.13 EGO26546.1 - 3.8 7.3 6.7 0.46 10.3 0.1 2.5 3 0 0 3 3 3 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus MFS_1 PF07690.16 EGO26548.1 - 3.5e-33 115.0 34.0 3.5e-33 115.0 34.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ParD PF09386.10 EGO26548.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Antitoxin ParD CopD PF05425.13 EGO26548.1 - 0.058 13.8 2.9 0.16 12.4 0.0 2.9 1 1 1 2 2 2 0 Copper resistance protein D GalKase_gal_bdg PF10509.9 EGO26549.1 - 0.094 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Galactokinase galactose-binding signature ABM PF03992.16 EGO26549.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 EGO26550.1 - 4.4e-30 104.8 31.5 1.2e-29 103.4 30.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4268 PF14088.6 EGO26551.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) CHAT PF12770.7 EGO26552.1 - 1.4e-31 110.0 0.0 2.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_1 PF00515.28 EGO26552.1 - 1.6e-11 43.5 11.7 0.2 11.6 0.1 10.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO26552.1 - 2.5e-08 34.1 13.7 4.4 7.7 0.0 9.5 7 1 3 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26552.1 - 7.2e-07 28.9 9.3 5.6 7.3 0.1 9.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO26552.1 - 3.3e-06 26.8 11.7 0.38 10.7 0.1 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO26552.1 - 1.8e-05 24.5 1.3 32 5.1 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Sel1 PF08238.12 EGO26552.1 - 0.00052 20.6 1.3 71 4.3 0.0 6.6 8 0 0 8 8 8 0 Sel1 repeat TPR_11 PF13414.6 EGO26552.1 - 0.0021 17.7 9.3 0.53 10.0 0.0 6.4 9 0 0 9 9 9 2 TPR repeat FRB_dom PF08771.11 EGO26552.1 - 0.0052 17.2 0.0 37 4.8 0.0 5.7 6 0 0 6 6 6 0 FKBP12-rapamycin binding domain TPR_7 PF13176.6 EGO26552.1 - 0.017 15.1 7.5 45 4.4 0.1 7.5 9 1 0 9 9 9 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 EGO26553.1 - 1.5e-56 191.8 0.0 2.9e-56 190.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGO26553.1 - 5.9e-46 157.4 0.7 1e-45 156.7 0.1 1.6 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 EGO26553.1 - 9e-32 110.5 0.0 1.7e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGO26553.1 - 2.7e-28 99.1 0.1 5.6e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EGO26553.1 - 4.6e-28 97.6 0.0 1.4e-27 96.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGO26553.1 - 1.6e-14 54.3 0.0 7.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 EGO26553.1 - 9.1e-10 39.0 0.0 1.9e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EGO26553.1 - 9.4e-05 22.7 0.2 0.00024 21.4 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGO26553.1 - 9.8e-05 21.8 0.2 0.00021 20.8 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGO26553.1 - 0.00027 20.8 0.0 0.00063 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.10 EGO26553.1 - 0.00037 20.3 0.4 0.0012 18.7 0.4 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_31 PF13847.6 EGO26553.1 - 0.074 12.8 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Aminotran_5 PF00266.19 EGO26554.1 - 9.6e-14 51.1 0.0 2.9e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGO26554.1 - 0.00021 20.6 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGO26554.1 - 0.0071 15.7 0.1 0.073 12.4 0.1 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 EGO26555.1 - 1.3e-17 63.8 44.7 1.7e-17 63.4 44.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCHC PF00098.23 EGO26558.1 - 4.1e-07 29.8 5.3 7.8e-07 28.9 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26558.1 - 6.5e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO26558.1 - 0.029 14.3 2.0 0.065 13.2 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Multi_ubiq PF14452.6 EGO26558.1 - 0.2 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Multiubiquitin RVP_2 PF08284.11 EGO26559.1 - 0.0022 17.8 0.1 0.45 10.3 0.0 2.2 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO26559.1 - 0.0033 18.0 0.0 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO26559.1 - 0.0035 18.0 0.0 0.0093 16.6 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease XPG_I_2 PF12813.7 EGO26564.1 - 6.7e-09 35.6 0.0 3.3e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.17 EGO26564.1 - 0.00015 22.1 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DUF2457 PF10446.9 EGO26564.1 - 0.0046 16.2 0.4 0.011 14.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) KDZ PF18758.1 EGO26567.1 - 9.7e-22 77.7 3.9 1.2e-21 77.3 3.9 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Hamartin PF04388.12 EGO26567.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein RRM_1 PF00076.22 EGO26568.1 - 0.0024 17.6 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 EGO26569.1 - 5.9e-05 23.0 0.9 0.00011 22.1 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO26569.1 - 0.098 12.8 3.5 0.16 12.1 3.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Plavaka PF18759.1 EGO26571.1 - 1.2e-38 133.2 0.0 1.6e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DNA_pol_D_N PF18018.1 EGO26573.1 - 1.7e-41 141.4 0.0 2.7e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EGO26573.1 - 7.2e-32 110.5 1.1 2.7e-30 105.3 1.1 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Nmad5 PF18757.1 EGO26574.1 - 0.21 11.8 10.2 0.29 11.3 10.2 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 DDHD PF02862.17 EGO26574.1 - 0.3 11.2 4.4 0.39 10.8 4.4 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 EGO26574.1 - 0.67 8.2 10.3 0.8 7.9 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 EGO26574.1 - 3.6 6.9 29.1 4.9 6.4 29.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FGF-BP1 PF06473.12 EGO26574.1 - 5 6.9 21.8 1.8 8.4 18.6 1.8 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) DUF4569 PF15133.6 EGO26574.1 - 7.2 6.2 12.0 20 4.7 12.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) NAD_kinase PF01513.21 EGO26575.1 - 1.4e-63 214.8 0.0 1.9e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGO26575.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CDC37_N PF03234.14 EGO26576.1 - 0.023 15.6 1.4 0.039 14.9 1.4 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF2497 PF10691.9 EGO26576.1 - 0.029 14.8 2.8 0.084 13.3 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2497) DUF826 PF05696.11 EGO26576.1 - 0.054 13.6 1.4 0.2 11.8 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF826) Cornichon PF03311.14 EGO26577.1 - 7.5e-54 181.2 10.4 8.7e-54 181.0 10.4 1.0 1 0 0 1 1 1 1 Cornichon protein DDE_3 PF13358.6 EGO26581.1 - 0.012 15.3 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease DNA_RNApol_7kD PF03604.13 EGO26581.1 - 0.12 12.1 7.1 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CAS_CSE1 PF03378.15 EGO26583.1 - 2.1e-121 405.5 4.3 3.1e-121 405.0 4.3 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EGO26583.1 - 2.7e-103 345.6 0.0 4.1e-103 345.0 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EGO26583.1 - 5.1e-13 48.7 0.0 3e-12 46.3 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGO26583.1 - 0.0026 17.8 2.0 0.054 13.5 0.1 3.4 3 1 0 3 3 3 1 Exportin 1-like protein DNA_pol_phi PF04931.13 EGO26583.1 - 0.12 10.5 0.1 0.29 9.2 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase phi Sec10 PF07393.11 EGO26584.1 - 8e-132 441.1 0.0 1e-131 440.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EGO26584.1 - 0.00049 19.9 0.8 0.00049 19.9 0.8 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGO26584.1 - 0.12 12.3 0.3 1.2 9.1 0.3 2.3 2 0 0 2 2 2 0 F-box-like Whi5 PF08528.11 EGO26585.1 - 3.8e-07 29.6 1.1 6.4e-07 28.8 1.1 1.4 1 0 0 1 1 1 1 Whi5 like RRT14 PF17075.5 EGO26585.1 - 0.38 10.9 3.6 2.6 8.1 2.2 2.2 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 CTP_transf_1 PF01148.20 EGO26586.1 - 0.0037 17.1 2.1 0.0068 16.2 2.2 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S8 PF00410.19 EGO26587.1 - 2.8e-25 88.7 0.1 3.8e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 EGO26588.1 - 2.3e-60 201.9 0.2 3e-60 201.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Tic110 PF16940.5 EGO26592.1 - 4.1 5.8 4.0 5.4 5.4 4.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Thaumatin PF00314.17 EGO26593.1 - 6.6e-72 241.6 11.9 7.6e-72 241.4 11.9 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EGO26593.1 - 0.0044 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF3302 PF11742.8 EGO26594.1 - 0.042 14.0 0.1 0.049 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) MMR_HSR1_Xtn PF16897.5 EGO26596.1 - 3e-40 136.5 1.2 3e-39 133.3 0.7 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGO26596.1 - 4.3e-24 84.3 0.1 7.6e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGO26596.1 - 3.4e-21 75.5 0.0 7.8e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO26596.1 - 4.8e-09 35.9 0.5 1.2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EGO26596.1 - 0.0072 15.3 0.4 0.028 13.4 0.2 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGO26596.1 - 0.02 14.9 0.5 7.8 6.5 0.5 2.5 1 1 1 2 2 2 0 Dynamin family Mor PF08765.11 EGO26596.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Mor transcription activator family RsgA_GTPase PF03193.16 EGO26596.1 - 0.45 10.4 2.6 1.9 8.4 0.3 2.7 2 1 1 3 3 3 0 RsgA GTPase Sec_GG PF07549.14 EGO26597.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif p450 PF00067.22 EGO26598.1 - 1.4e-57 195.5 0.0 2.1e-57 194.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FOXO_KIX_bdg PF16675.5 EGO26599.1 - 0.11 12.8 2.9 0.26 11.6 2.9 1.6 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 MitoNEET_N PF10660.9 EGO26599.1 - 0.14 12.2 0.1 0.46 10.6 0.1 1.8 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Ferlin_C PF16165.5 EGO26599.1 - 0.16 11.9 0.0 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferlin C-terminus Syndecan PF01034.20 EGO26599.1 - 0.52 10.3 3.2 1.3 9.0 3.2 1.6 1 0 0 1 1 1 0 Syndecan domain DUF4834 PF16118.5 EGO26599.1 - 1.6 9.7 2.8 8.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ANAPC4_WD40 PF12894.7 EGO26600.1 - 6.2e-18 64.9 4.1 9.6e-06 25.8 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO26600.1 - 1.7e-15 57.1 15.8 1.7e-05 25.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 EGO26600.1 - 1.4e-05 25.0 0.0 0.0044 16.9 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGO26600.1 - 0.0013 17.7 0.0 0.064 12.2 0.0 2.9 2 2 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Adap_comp_sub PF00928.21 EGO26601.1 - 2.3e-93 312.4 0.1 4.9e-93 311.3 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO26601.1 - 1.2e-06 28.5 0.4 2.1e-06 27.7 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGO26601.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PQ-loop PF04193.14 EGO26602.1 - 7.2e-18 64.1 20.1 1.6e-10 40.6 2.9 3.4 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 EGO26602.1 - 0.0052 17.6 4.4 0.7 10.7 0.0 2.8 3 0 0 3 3 3 2 ER lumen protein retaining receptor Retrotrans_gag PF03732.17 EGO26604.1 - 8.9e-08 32.3 2.5 1e-07 32.1 0.3 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO26604.1 - 2.1e-06 27.6 3.1 4.2e-06 26.6 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle BMFP PF04380.13 EGO26604.1 - 0.16 12.5 2.0 94 3.6 0.0 3.5 3 0 0 3 3 3 0 Membrane fusogenic activity TPR_12 PF13424.6 EGO26605.1 - 3e-109 357.4 54.8 1.4e-18 66.9 0.7 9.5 3 3 7 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 EGO26605.1 - 5.2e-93 302.7 22.2 2.2e-10 40.1 0.4 12.1 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_7 PF13176.6 EGO26605.1 - 4.7e-42 139.0 26.8 0.0021 17.9 0.3 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26605.1 - 1.1e-39 132.7 42.7 0.0001 22.0 0.2 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26605.1 - 8.2e-37 122.4 40.0 0.00052 19.9 0.4 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_8 PF13181.6 EGO26605.1 - 5.4e-31 104.2 46.9 0.0017 18.4 0.3 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO26605.1 - 8.2e-28 97.7 20.4 1.2e-10 41.3 0.1 4.2 1 1 1 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 EGO26605.1 - 2.9e-25 86.8 13.8 0.089 13.7 0.2 11.9 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGO26605.1 - 1.4e-20 73.6 29.6 0.00012 22.6 0.2 9.5 4 3 6 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 EGO26605.1 - 2.8e-17 63.1 17.4 0.0019 18.8 0.1 10.6 10 2 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO26605.1 - 4e-12 46.2 24.9 0.062 13.5 0.3 8.4 2 2 5 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGO26605.1 - 3.7e-11 42.9 38.6 0.24 12.1 0.5 10.8 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_4 PF07721.14 EGO26605.1 - 4.4e-11 42.3 0.0 25 5.9 0.0 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO26605.1 - 1.6e-09 37.5 24.6 9.7 6.8 0.3 11.9 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGO26605.1 - 9e-08 32.0 39.7 2.2 8.4 0.2 10.9 11 0 0 11 11 11 4 Tetratricopeptide repeat PPR PF01535.20 EGO26605.1 - 4.8e-06 26.5 13.5 32 5.1 0.0 9.7 12 0 0 12 12 11 0 PPR repeat TPR_5 PF12688.7 EGO26605.1 - 5.5e-05 23.4 8.9 0.0012 19.1 0.4 4.9 4 1 1 5 5 5 1 Tetratrico peptide repeat MIT PF04212.18 EGO26605.1 - 0.0021 18.1 21.5 0.82 9.8 0.2 6.4 6 1 1 7 7 6 2 MIT (microtubule interacting and transport) domain HopA1 PF17914.1 EGO26605.1 - 0.037 13.8 0.2 34 4.1 0.0 4.1 4 0 0 4 4 4 0 HopA1 effector protein family Coatomer_E PF04733.14 EGO26605.1 - 0.062 12.7 8.3 3 7.2 0.1 4.6 2 1 1 4 4 4 0 Coatomer epsilon subunit Peripla_BP_2 PF01497.18 EGO26605.1 - 0.16 11.5 0.4 4.1 6.9 0.0 2.7 2 1 0 2 2 2 0 Periplasmic binding protein DUF2225 PF09986.9 EGO26605.1 - 0.64 9.7 16.3 0.39 10.4 3.9 3.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) SHNi-TPR PF10516.9 EGO26605.1 - 0.65 9.5 5.5 15 5.2 0.1 4.6 4 0 0 4 4 4 0 SHNi-TPR DUF5113 PF17140.4 EGO26605.1 - 0.84 9.4 7.5 8.9 6.1 0.0 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) Lectin_N PF03954.14 EGO26605.1 - 0.85 9.4 5.0 25 4.6 0.0 3.5 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain RPN6_N PF18055.1 EGO26605.1 - 1.4 9.3 17.6 1.5 9.2 0.8 5.7 4 2 2 7 7 7 0 26S proteasome regulatory subunit RPN6 N-terminal domain YfdX PF10938.8 EGO26605.1 - 2.1 8.3 4.5 38 4.2 0.1 3.8 3 1 1 4 4 4 0 YfdX protein BTAD PF03704.17 EGO26605.1 - 4 7.9 12.4 7.6 7.0 0.2 4.3 3 1 2 5 5 4 0 Bacterial transcriptional activator domain NB-ARC PF00931.22 EGO26606.1 - 2.4e-12 46.6 0.0 3.1e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGO26606.1 - 1.1e-08 35.6 0.0 1.8e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGO26606.1 - 0.0006 19.8 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EGO26606.1 - 0.0016 18.4 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EGO26606.1 - 0.0039 17.1 0.0 0.0084 16.0 0.0 1.6 1 1 0 1 1 1 1 NACHT domain TniB PF05621.11 EGO26606.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EGO26606.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO26606.1 - 0.078 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 EGO26609.1 - 1.7e-17 63.7 0.0 4e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO26609.1 - 0.00066 19.8 0.3 0.0017 18.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO26609.1 - 0.00075 19.2 0.3 0.0012 18.5 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 EGO26609.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EGO26609.1 - 0.05 12.8 0.3 0.12 11.6 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO26609.1 - 0.062 12.1 0.7 0.16 10.8 0.4 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EGO26609.1 - 0.12 11.6 0.3 0.2 10.9 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EGO26609.1 - 0.51 10.9 1.9 3.2 8.4 0.6 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.21 EGO26610.1 - 6.3e-74 249.6 0.0 3e-71 240.7 0.0 2.0 1 1 0 1 1 1 1 Amidase His_Phos_2 PF00328.22 EGO26611.1 - 3.5e-45 155.0 0.0 4.3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.22 EGO26612.1 - 4.2e-73 246.7 0.0 7.3e-73 245.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MethyTransf_Reg PF10119.9 EGO26612.1 - 0.023 15.4 0.1 0.095 13.4 0.0 2.0 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain DUF3684 PF12449.8 EGO26613.1 - 0 1246.9 0.0 0 1246.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) TrmO_C PF18389.1 EGO26613.1 - 0.056 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain HATPase_c_3 PF13589.6 EGO26613.1 - 0.081 12.8 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spo7 PF03907.13 EGO26615.1 - 1.4e-39 135.9 0.9 3.6e-39 134.5 0.9 1.6 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 EGO26615.1 - 0.02 15.3 0.1 0.052 13.9 0.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 188 MFS_1 PF07690.16 EGO26616.1 - 2.2e-22 79.5 71.1 6.2e-19 68.1 40.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PHP PF02811.19 EGO26617.1 - 1.1e-10 42.1 0.0 1.8e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 PHP domain DUF1688 PF07958.11 EGO26618.1 - 7.6e-172 571.8 0.0 8.5e-172 571.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.6 EGO26619.1 - 2.2e-11 43.0 13.7 2.2e-11 43.0 13.7 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EGO26619.1 - 0.0014 17.6 1.8 0.0027 16.6 1.8 1.5 1 1 0 1 1 1 1 MFS_1 like family ETF_QO PF05187.13 EGO26620.1 - 2.8e-35 120.6 0.0 6.1e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EGO26620.1 - 7.2e-09 35.7 0.0 0.00019 21.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO26620.1 - 6.2e-06 26.4 0.0 2.3e-05 24.5 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO26620.1 - 3e-05 23.4 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EGO26620.1 - 6e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO26620.1 - 0.00014 21.1 0.1 0.00046 19.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGO26620.1 - 0.00024 20.3 0.1 0.00076 18.6 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGO26620.1 - 0.00033 20.0 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGO26620.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO26620.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGO26620.1 - 0.0033 16.2 0.0 0.005 15.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EGO26620.1 - 0.012 16.1 0.0 2.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO26620.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EGO26620.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EGO26620.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.32 EGO26621.1 - 2.1e-17 63.1 3.9 7.1e-05 23.5 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26621.1 - 1.3e-06 28.7 0.0 2 8.8 0.0 4.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGO26621.1 - 1.2 9.7 3.7 22 5.7 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.25 EGO26622.1 - 1.4e-53 182.0 0.0 3e-51 174.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26622.1 - 6.6e-26 91.1 0.0 9.6e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO26622.1 - 1.3e-08 34.5 0.2 9.7e-06 25.1 0.1 2.8 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGO26622.1 - 1.2e-05 25.4 0.1 3.1e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO26622.1 - 0.00051 18.9 0.0 0.00095 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGO26622.1 - 0.001 18.7 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGO26622.1 - 0.0013 17.7 0.0 0.0028 16.7 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO26622.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mitoc_mL59 PF18126.1 EGO26622.1 - 0.024 14.9 0.0 0.064 13.6 0.0 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Seadorna_VP7 PF07387.11 EGO26622.1 - 0.04 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MarR PF01047.22 EGO26622.1 - 0.057 13.4 0.0 3.8 7.5 0.0 2.7 2 0 0 2 2 2 0 MarR family SNF2_N PF00176.23 EGO26624.1 - 2.1e-71 240.5 0.2 3.5e-71 239.8 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO26624.1 - 6.2e-22 78.1 0.0 1.6e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGO26624.1 - 9.6e-06 25.0 1.7 0.00013 21.3 0.0 2.9 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EGO26624.1 - 0.027 13.7 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 EGO26624.1 - 0.93 9.1 3.5 4.7 6.8 0.0 3.3 3 1 1 4 4 4 0 DEAD_2 DUF3245 PF11595.8 EGO26624.1 - 4.2 7.8 15.2 9.2 6.7 3.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) ArfGap PF01412.18 EGO26625.1 - 3.1e-38 130.5 0.3 4.8e-38 129.8 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5572 PF17733.1 EGO26626.1 - 6.3e-21 74.0 0.7 1.2e-20 73.1 0.7 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Toprim_Crpt PF13342.6 EGO26626.1 - 0.044 13.8 0.1 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase UDPG_MGDP_dh_N PF03721.14 EGO26628.1 - 3.7e-59 199.4 0.0 6.3e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EGO26628.1 - 2.1e-36 124.5 0.0 2.2e-35 121.3 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EGO26628.1 - 3.8e-30 104.0 0.0 1.2e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 EGO26628.1 - 0.021 15.1 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGO26628.1 - 0.068 13.8 0.1 1.1 9.8 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 EGO26628.1 - 0.14 12.2 0.0 4.7 7.3 0.0 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain zf-CCHC PF00098.23 EGO26629.1 - 1.6e-05 24.8 4.7 1.6e-05 24.8 4.7 1.9 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26629.1 - 0.031 14.5 1.3 0.064 13.5 0.4 2.0 2 1 0 2 2 2 0 Retrotransposon gag protein DUF4939 PF16297.5 EGO26629.1 - 0.079 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC_3 PF13917.6 EGO26629.1 - 0.098 12.6 3.0 0.19 11.7 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle BUD22 PF09073.10 EGO26630.1 - 0.0025 17.2 10.9 0.0035 16.8 10.9 1.2 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 EGO26630.1 - 0.0099 16.0 14.4 0.0099 16.0 14.4 1.4 2 0 0 2 2 2 1 YL1 nuclear protein SR-25 PF10500.9 EGO26630.1 - 0.021 14.4 11.2 0.035 13.7 11.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Afi1 PF07792.12 EGO26630.1 - 0.022 15.2 2.0 0.022 15.2 2.0 1.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 EGO26630.1 - 0.024 12.9 6.6 0.024 13.0 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 EGO26630.1 - 0.42 9.6 6.5 0.8 8.7 6.5 1.4 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 EGO26630.1 - 2.7 6.0 15.8 4.4 5.3 15.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi zf-CCHC_4 PF14392.6 EGO26632.1 - 0.029 14.1 1.6 0.045 13.5 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO26632.1 - 0.03 14.1 0.4 0.055 13.2 0.4 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger DUF1771 PF08590.10 EGO26632.1 - 0.11 12.9 0.4 0.17 12.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DUF3866 PF12982.7 EGO26633.1 - 0.13 11.4 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Aminotran_1_2 PF00155.21 EGO26637.1 - 1.4e-53 182.4 0.0 6.5e-43 147.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 EGO26637.1 - 0.0024 16.7 0.0 0.0044 15.8 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 EGO26637.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Peptidase_M20 PF01546.28 EGO26638.1 - 3.7e-34 118.2 0.0 5.8e-34 117.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO26638.1 - 4.3e-10 39.5 0.0 6.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SUZ PF12752.7 EGO26639.1 - 4.3e-13 49.8 0.6 4.3e-13 49.8 0.6 2.2 2 1 0 2 2 2 1 SUZ domain FA_desaturase PF00487.24 EGO26642.1 - 6.5e-22 78.6 29.4 1e-21 78.0 29.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGO26642.1 - 8.8e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_3 PF07859.13 EGO26643.1 - 8.4e-46 156.5 0.0 1.2e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO26643.1 - 7.1e-07 28.9 0.2 0.0038 16.7 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EGO26643.1 - 2.2e-05 23.5 0.0 0.00015 20.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 EGO26643.1 - 0.0024 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 EGO26643.1 - 0.0044 16.0 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 EGO26643.1 - 0.018 14.6 0.0 0.064 12.7 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase AXE1 PF05448.12 EGO26643.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EGO26643.1 - 0.21 11.2 0.2 1.1 8.9 0.2 2.3 1 1 0 1 1 1 0 Putative esterase FA_desaturase PF00487.24 EGO26644.1 - 3.1e-26 92.7 26.6 4.6e-26 92.2 26.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGO26644.1 - 6.8e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Dus PF01207.17 EGO26646.1 - 1.7e-50 171.9 0.0 6.3e-50 170.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EGO26646.1 - 7.2e-06 25.8 3.2 0.061 13.2 0.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGO26646.1 - 0.00016 21.4 7.0 0.002 17.9 1.2 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EGO26646.1 - 0.014 16.1 2.3 0.14 12.8 0.1 2.7 3 0 0 3 3 3 0 Torus domain Mis14 PF08641.12 EGO26646.1 - 0.043 14.1 0.6 0.074 13.4 0.6 1.3 1 0 0 1 1 1 0 Kinetochore protein Mis14 like zf_CCCH_4 PF18345.1 EGO26646.1 - 0.76 9.9 6.9 1.5 9.0 1.2 2.5 2 0 0 2 2 2 0 Zinc finger domain Complex1_LYR PF05347.15 EGO26647.1 - 6.4e-06 26.1 0.8 0.0057 16.7 0.0 3.1 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Aminopep PF10023.9 EGO26647.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative aminopeptidase Aminotran_1_2 PF00155.21 EGO26648.1 - 2.3e-42 145.5 0.0 3.1e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_14 PF17754.1 EGO26648.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 MftR C-terminal domain Aminotran_3 PF00202.21 EGO26648.1 - 0.2 10.3 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III WD40 PF00400.32 EGO26649.1 - 6.3e-19 68.0 4.3 9.8e-06 26.2 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26649.1 - 0.026 14.8 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nha1_C PF08619.10 EGO26649.1 - 0.046 12.9 7.9 0.073 12.3 7.9 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Abhydrolase_6 PF12697.7 EGO26651.1 - 2e-13 51.5 0.1 2.7e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family HMGL-like PF00682.19 EGO26652.1 - 2.1e-44 152.0 0.0 3.6e-44 151.3 0.0 1.4 1 1 0 1 1 1 1 HMGL-like DUF775 PF05603.12 EGO26653.1 - 1.3e-55 188.0 0.0 1.5e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Fungal_trans PF04082.18 EGO26654.1 - 9.5e-35 119.9 0.0 4.5e-34 117.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Dimer_Tnp_hAT PF05699.14 EGO26656.1 - 0.0001 22.0 0.1 0.00017 21.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UCH PF00443.29 EGO26657.1 - 6.6e-07 29.1 0.0 9.9e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 EGO26657.1 - 0.00017 21.3 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.16 EGO26657.1 - 0.00074 19.2 0.0 0.003 17.2 0.0 2.1 2 0 0 2 2 2 1 CUE domain UBA PF00627.31 EGO26657.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain Glyco_hydro_15 PF00723.21 EGO26657.1 - 0.034 12.9 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 UIM PF02809.20 EGO26657.1 - 0.12 12.3 1.5 0.46 10.5 0.9 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Copper-fist PF00649.18 EGO26659.1 - 1.9e-16 59.3 1.4 1.9e-16 59.3 1.4 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain DnaJ PF00226.31 EGO26661.1 - 2.4e-17 62.8 0.5 7e-17 61.3 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain DUF2714 PF10896.8 EGO26661.1 - 0.06 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) Pkinase_fungal PF17667.1 EGO26666.1 - 1e-18 67.3 0.0 1.1e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pex24p PF06398.11 EGO26667.1 - 6.6e-08 31.9 2.3 1e-07 31.3 2.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pkinase PF00069.25 EGO26668.1 - 1.7e-54 185.0 0.0 3e-54 184.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26668.1 - 1.9e-30 106.0 0.1 2e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO26668.1 - 6.2e-05 22.4 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGO26668.1 - 0.00017 20.5 0.0 0.00036 19.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGO26668.1 - 0.00019 21.1 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGO26668.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO26668.1 - 0.0053 16.7 0.1 0.053 13.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2098 PF09871.9 EGO26668.1 - 0.066 13.5 0.2 0.16 12.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Kdo PF06293.14 EGO26668.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_A_exo1 PF01612.20 EGO26669.1 - 5e-13 49.1 0.0 6.9e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease 4HBT PF03061.22 EGO26670.1 - 3.2e-07 30.6 0.0 5.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily FA_desaturase PF00487.24 EGO26672.1 - 5.9e-11 42.7 6.8 5.9e-11 42.7 6.8 1.8 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EGO26672.1 - 3.5e-06 27.2 0.0 7.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Proteasome PF00227.26 EGO26673.1 - 5e-39 133.8 0.0 6.2e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mre11_DNA_bind PF04152.14 EGO26674.1 - 1.3e-50 172.0 0.0 3.4e-50 170.7 0.0 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGO26674.1 - 1.8e-14 54.7 0.4 3.7e-14 53.7 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO26674.1 - 0.00012 22.3 0.0 0.0026 18.0 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.16 EGO26675.1 - 6.8e-18 65.0 23.7 8.2e-18 64.7 23.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO26675.1 - 0.00016 21.9 41.6 0.0061 16.7 16.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family PAPS_reduct PF01507.19 EGO26676.1 - 3.6e-27 95.5 0.0 8.1e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.21 EGO26677.1 - 4.5e-53 180.2 0.0 6.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO26677.1 - 6.5e-15 55.4 0.2 3.6e-14 52.9 0.2 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO26677.1 - 9.3e-06 24.9 0.0 2.3e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO26677.1 - 1.1e-05 24.7 0.2 0.0034 16.6 0.3 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGO26677.1 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGO26678.1 - 1.3e-154 514.6 0.0 1.5e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO26678.1 - 3.4e-71 239.5 0.0 4.8e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO26678.1 - 0.00094 18.4 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO26678.1 - 0.012 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_2 PF00891.18 EGO26680.1 - 8.2e-24 84.1 0.0 7.4e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 EGO26680.1 - 0.00031 20.7 0.6 0.00079 19.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_25 PF13649.6 EGO26680.1 - 0.027 15.2 0.0 0.065 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MarR PF01047.22 EGO26680.1 - 0.045 13.7 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 MarR family MTS PF05175.14 EGO26680.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MarR_2 PF12802.7 EGO26680.1 - 0.18 11.7 0.1 16 5.4 0.0 2.7 3 0 0 3 3 3 0 MarR family RNA_pol_Rpc34 PF05158.12 EGO26680.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Alpha_kinase PF02816.18 EGO26681.1 - 4.2e-17 62.9 0.0 6.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.16 EGO26683.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin 4HBT PF03061.22 EGO26684.1 - 4.8e-11 42.9 0.0 6.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EGO26684.1 - 2.1e-05 25.0 0.0 2.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EGO26684.1 - 8.2e-05 22.0 0.2 0.00023 20.6 0.2 1.6 1 1 1 2 2 2 1 Acyl-ACP thioesterase Vps62 PF06101.11 EGO26685.1 - 0.00013 20.4 0.0 0.00015 20.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Promethin PF16015.5 EGO26686.1 - 1.4e-11 44.3 17.0 1.8e-11 43.9 17.0 1.2 1 0 0 1 1 1 1 Promethin DUF4191 PF13829.6 EGO26686.1 - 1.5 8.1 6.8 1.1 8.6 5.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DUF5480 PF17576.2 EGO26686.1 - 1.9 8.5 7.8 3.7 7.6 7.8 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5480) CBM_1 PF00734.18 EGO26687.1 - 3.3e-10 39.7 10.2 3.3e-10 39.7 10.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Qn_am_d_aII PF14930.6 EGO26687.1 - 0.09 13.1 0.1 7.9 6.9 0.0 2.3 1 1 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II p450 PF00067.22 EGO26688.1 - 1e-74 251.9 0.0 3.2e-73 247.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Piwi PF02171.17 EGO26689.1 - 8e-84 281.4 0.0 1.1e-83 281.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGO26689.1 - 4.6e-22 79.1 0.0 1e-21 78.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGO26689.1 - 5.1e-20 70.9 0.1 1.2e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EGO26689.1 - 1.4e-16 60.5 0.0 2.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EGO26689.1 - 5.5e-12 45.8 0.0 1.6e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 EGO26689.1 - 0.0042 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Retrotrans_gag PF03732.17 EGO26691.1 - 8.2e-05 22.8 1.9 0.0001 22.5 0.1 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EGO26692.1 - 0.006 17.2 0.0 0.0067 17.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO26692.1 - 0.03 14.9 0.0 0.03 14.9 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ApbA PF02558.16 EGO26693.1 - 7.4e-19 67.9 0.0 1.4e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGO26693.1 - 1e-17 64.5 0.0 4.9e-16 59.1 0.0 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 EGO26693.1 - 0.056 12.8 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 ThiF family TPT PF03151.16 EGO26694.1 - 5e-36 124.5 9.2 1.1e-35 123.4 9.2 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO26694.1 - 6.2e-08 32.9 23.1 9.5e-06 25.8 6.2 3.0 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGO26694.1 - 6.9e-08 32.1 8.9 0.00044 19.6 1.5 2.2 2 0 0 2 2 2 2 UAA transporter family zf-RING_UBOX PF13445.6 EGO26695.1 - 1.5e-07 31.3 2.0 1.5e-07 31.3 2.0 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO26695.1 - 2.2e-07 30.6 2.9 2.2e-07 30.6 2.9 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO26695.1 - 2.9e-07 30.2 3.4 2.9e-07 30.2 3.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO26695.1 - 3e-07 30.2 4.3 3e-07 30.2 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO26695.1 - 1.3e-06 28.6 4.1 1.3e-06 28.6 4.1 2.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGO26695.1 - 1.3e-05 25.3 1.6 1.3e-05 25.3 1.6 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGO26695.1 - 0.00011 22.1 3.9 0.00011 22.1 3.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGO26695.1 - 0.0081 16.0 0.1 0.0081 16.0 0.1 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGO26695.1 - 0.012 15.4 5.2 0.012 15.4 5.2 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Pellino PF04710.14 EGO26695.1 - 0.034 12.8 0.4 0.063 11.9 0.4 1.3 1 0 0 1 1 1 0 Pellino zf-RING_4 PF14570.6 EGO26695.1 - 3 7.7 13.4 4.5 7.2 4.6 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 EGO26695.1 - 3.7 7.4 8.4 0.16 11.7 2.5 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FYVE PF01363.21 EGO26695.1 - 7.1 6.8 6.3 1.2 9.4 1.2 2.3 2 1 0 2 2 2 0 FYVE zinc finger AAA_11 PF13086.6 EGO26696.1 - 1.5e-62 211.7 0.0 1.5e-62 211.7 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_12 PF13087.6 EGO26696.1 - 2.7e-57 193.6 0.0 4.7e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGO26696.1 - 3e-11 43.5 0.0 0.02 14.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EGO26696.1 - 1.3e-09 38.6 0.0 1.3e-08 35.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO26696.1 - 8.7e-09 35.4 0.0 9.5e-07 28.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO26696.1 - 0.00011 22.5 0.1 0.00088 19.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGO26696.1 - 0.00014 21.9 0.0 0.0081 16.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 EGO26696.1 - 0.00062 19.5 0.1 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EGO26696.1 - 0.00077 18.8 0.3 0.33 10.1 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) GATase_6 PF13522.6 EGO26696.1 - 0.0013 18.9 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 2 Glutamine amidotransferase domain UvrD-helicase PF00580.21 EGO26696.1 - 0.0037 16.8 5.5 0.015 14.8 5.5 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 EGO26696.1 - 0.0051 17.2 0.0 0.021 15.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PI3K_1B_p101 PF10486.9 EGO26696.1 - 0.012 13.4 4.2 0.018 12.9 4.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PhoH PF02562.16 EGO26696.1 - 0.015 14.8 0.0 0.49 9.8 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_24 PF13479.6 EGO26696.1 - 0.017 14.8 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO26696.1 - 0.032 14.6 0.5 0.088 13.2 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EGO26696.1 - 0.042 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGO26696.1 - 0.054 14.0 0.0 0.26 11.8 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Ndc1_Nup PF09531.10 EGO26696.1 - 0.075 11.7 2.2 0.1 11.3 2.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_33 PF13671.6 EGO26696.1 - 0.1 12.7 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EGO26696.1 - 0.15 11.2 0.0 8.9 5.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Presenilin PF01080.17 EGO26696.1 - 2.8 6.6 4.7 4.5 5.9 4.7 1.2 1 0 0 1 1 1 0 Presenilin M20_dimer PF07687.14 EGO26697.1 - 1.2e-06 28.4 0.1 3.3e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EGO26697.1 - 2.5e-06 27.3 0.0 4.9e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 EGO26698.1 - 5.3e-06 26.3 0.0 8.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO26698.1 - 0.0042 17.0 0.1 0.0086 16.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Luteo_coat PF00894.18 EGO26699.1 - 0.14 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Luteovirus coat protein UcrQ PF02939.16 EGO26700.1 - 1.9e-31 107.8 2.2 2.1e-31 107.7 2.2 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 EGO26700.1 - 0.02 15.3 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Ost4 PF10215.9 EGO26701.1 - 9.6e-13 47.7 2.2 1.7e-12 46.9 2.2 1.4 1 0 0 1 1 1 1 Oligosaccaryltransferase Hydrophobin PF01185.18 EGO26704.1 - 2.7e-26 92.0 7.9 3.6e-26 91.6 7.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin BMFP PF04380.13 EGO26705.1 - 0.0078 16.7 0.3 2.6 8.6 0.0 3.2 3 0 0 3 3 3 2 Membrane fusogenic activity Fer2 PF00111.27 EGO26706.1 - 5.4e-11 42.3 0.0 8.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain BPL_N PF09825.9 EGO26707.1 - 4.1e-25 88.7 0.0 9.9e-25 87.4 0.0 1.6 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EGO26707.1 - 9.2e-19 67.7 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EGO26707.1 - 0.43 10.5 2.2 2.9 7.9 2.2 2.2 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain Frataxin_Cyay PF01491.16 EGO26708.1 - 3.3e-38 130.1 0.0 4.7e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Pkinase PF00069.25 EGO26710.1 - 1.3e-15 57.5 0.0 4.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 EGO26710.1 - 4.1e-15 55.9 17.4 1.5e-07 32.0 1.6 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 EGO26710.1 - 1.3e-10 40.5 12.5 0.039 14.2 0.1 6.0 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.17 EGO26710.1 - 3.1e-07 29.9 0.0 0.0038 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.6 EGO26710.1 - 1e-05 25.8 0.6 0.84 10.1 0.0 4.4 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 EGO26710.1 - 0.0072 16.4 7.4 4 7.5 1.0 4.1 2 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EGO26710.1 - 0.033 14.5 3.4 0.57 10.5 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion tRNA-synt_2b PF00587.25 EGO26711.1 - 2.1e-34 119.0 0.0 3.9e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGO26711.1 - 4.2e-16 58.9 0.1 1.4e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 EGO26711.1 - 1.3e-13 50.8 0.0 2.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 EGO26711.1 - 5.2e-12 45.7 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HSP20 PF00011.21 EGO26713.1 - 3.9e-13 49.4 0.0 5.5e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO26713.1 - 4.2e-05 23.0 0.0 0.00013 21.5 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA COesterase PF00135.28 EGO26714.1 - 1.9e-84 284.4 1.4 2e-83 281.0 1.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO26714.1 - 2.6e-11 43.8 0.3 4.4e-10 39.8 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO26714.1 - 0.00087 18.8 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGO26714.1 - 0.11 12.2 0.4 0.34 10.5 0.4 1.7 1 1 0 1 1 1 0 Putative esterase DUF874 PF05917.11 EGO26715.1 - 0.3 10.1 4.5 0.32 10.0 4.5 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) ARGLU PF15346.6 EGO26715.1 - 1.1 9.1 16.8 6.6 6.6 16.8 1.9 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Oberon_cc PF16312.5 EGO26715.1 - 1.3 8.9 12.0 3.9 7.4 12.0 1.8 1 1 0 1 1 1 0 Coiled-coil region of Oberon Fungal_trans PF04082.18 EGO26717.1 - 6.9e-10 38.4 0.5 1.8e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain TBCC PF07986.12 EGO26719.1 - 3.5e-24 84.9 2.9 5.7e-24 84.2 2.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGO26719.1 - 1.2e-12 48.3 0.0 2.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Focal_AT PF03623.13 EGO26719.1 - 0.052 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region zf-rbx1 PF12678.7 EGO26720.1 - 2.6e-24 85.2 12.9 3.9e-24 84.7 12.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO26720.1 - 3.1e-16 59.2 9.5 4.1e-16 58.8 9.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGO26720.1 - 7.5e-06 26.2 15.4 0.0003 21.1 15.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGO26720.1 - 0.0012 18.7 11.8 0.024 14.5 11.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO26720.1 - 0.0015 18.3 14.6 0.0019 18.0 9.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGO26720.1 - 0.2 11.8 9.3 0.96 9.7 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EGO26720.1 - 0.22 11.4 10.9 0.68 9.8 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO26720.1 - 0.25 11.4 7.1 0.86 9.7 7.1 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGO26720.1 - 0.53 9.9 14.3 0.17 11.5 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGO26720.1 - 1.5 8.6 17.0 87 3.0 17.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger COesterase PF00135.28 EGO26724.1 - 1.7e-40 139.4 0.4 9.5e-32 110.5 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO26724.1 - 0.00076 19.4 0.0 0.0071 16.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DDE_3 PF13358.6 EGO26725.1 - 1.5e-08 34.5 0.1 1.5e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF874 PF05917.11 EGO26727.1 - 0.021 13.9 7.3 0.023 13.8 7.3 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Golgin_A5 PF09787.9 EGO26727.1 - 0.027 14.0 7.4 0.027 14.0 7.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAUS5 PF14817.6 EGO26727.1 - 0.093 11.5 9.8 0.094 11.5 9.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1840 PF08895.11 EGO26727.1 - 0.13 12.6 6.6 0.13 12.6 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) HIP1_clath_bdg PF16515.5 EGO26727.1 - 0.17 12.5 13.1 0.22 12.1 13.1 1.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 EGO26727.1 - 0.46 9.8 5.5 0.46 9.8 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIEZO PF15917.5 EGO26727.1 - 0.46 9.9 8.2 0.51 9.8 8.2 1.1 1 0 0 1 1 1 0 Piezo Atg14 PF10186.9 EGO26727.1 - 0.61 9.1 6.5 0.59 9.2 6.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YdfA_immunity PF12127.8 EGO26727.1 - 0.66 9.0 5.8 0.7 8.9 5.8 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial DivIC PF04977.15 EGO26727.1 - 2.8 7.8 10.3 17 5.2 9.3 2.0 1 1 1 2 2 2 0 Septum formation initiator COesterase PF00135.28 EGO26728.1 - 8.1e-42 143.7 0.6 7.3e-32 110.9 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO26728.1 - 0.0031 17.4 0.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DDE_3 PF13358.6 EGO26729.1 - 1.5e-08 34.5 0.1 1.5e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Repressor_Mnt PF11423.8 EGO26731.1 - 0.0018 18.0 2.8 0.028 14.2 0.0 2.5 2 0 0 2 2 2 2 Regulatory protein Mnt Cdh1_DBD_1 PF18196.1 EGO26731.1 - 1.7 9.0 5.1 2.8 8.3 5.1 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF4470 PF14737.6 EGO26732.1 - 2.9e-24 85.1 0.7 5.6e-24 84.2 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TehB PF03848.14 EGO26732.1 - 0.061 12.7 0.1 17 4.8 0.0 3.0 3 0 0 3 3 3 0 Tellurite resistance protein TehB CRC_subunit PF08624.10 EGO26733.1 - 2.4e-44 151.1 0.0 3.8e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cnd2 PF05786.14 EGO26733.1 - 0.85 8.2 7.2 0.6 8.7 5.6 1.4 2 0 0 2 2 2 0 Condensin complex subunit 2 Ribosomal_L41 PF05162.13 EGO26734.1 - 4e-08 33.2 26.4 8.3e-08 32.2 26.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L41 SMG1 PF15785.5 EGO26735.1 - 0.0026 16.3 0.0 0.0029 16.1 0.0 1.1 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 Abhydrolase_2 PF02230.16 EGO26736.1 - 5.6e-11 42.7 0.0 9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGO26736.1 - 0.00092 19.9 0.2 0.0012 19.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGO26736.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO26739.1 - 1.3e-30 106.5 0.0 2.4e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGO26739.1 - 1.7e-07 31.2 0.0 0.012 15.3 0.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EGO26739.1 - 1.7e-07 30.7 0.5 0.00019 20.8 0.3 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO26739.1 - 6.6e-06 26.0 0.2 1.7e-05 24.6 0.2 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 EGO26739.1 - 1.8e-05 23.6 0.1 0.0029 16.3 0.1 2.4 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 EGO26739.1 - 3.4e-05 23.5 0.0 7.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGO26739.1 - 0.012 15.5 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EGO26739.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold NACHT PF05729.12 EGO26740.1 - 0.0003 20.8 0.0 0.00072 19.5 0.0 1.5 1 1 0 1 1 1 1 NACHT domain DUF1308 PF07000.11 EGO26741.1 - 5e-05 23.3 0.1 0.45 10.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1308) Abhydrolase_6 PF12697.7 EGO26742.1 - 0.0015 19.1 2.4 0.0033 18.0 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family RVT_2 PF07727.14 EGO26743.1 - 9.6e-05 22.1 0.1 9.8e-05 22.1 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EGO26744.1 - 6e-06 26.1 1.8 1.4e-05 25.0 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26744.1 - 9.4e-05 22.6 0.6 0.00039 20.7 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein HTH_23 PF13384.6 EGO26748.1 - 2.1e-06 27.4 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EGO26748.1 - 0.017 14.6 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 EGO26748.1 - 0.043 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 EGO26748.1 - 0.05 13.7 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 EGO26748.1 - 0.093 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EGO26748.1 - 0.21 11.9 0.0 0.45 10.9 0.0 1.5 2 0 0 2 2 2 0 Transposase Abhydrolase_6 PF12697.7 EGO26749.1 - 1.2e-12 48.9 2.5 1.2e-12 48.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO26749.1 - 3.4e-05 23.6 0.0 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGO26749.1 - 5.6e-05 22.9 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGO26749.1 - 0.0034 16.9 0.0 0.0079 15.7 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGO26749.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGO26749.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 EGO26749.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 EGO26749.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PAF-AH_p_II PF03403.13 EGO26749.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II SET PF00856.28 EGO26753.1 - 7.2e-17 62.3 0.0 9e-17 62.0 0.0 1.3 1 1 0 1 1 1 1 SET domain tRNA-synt_2b PF00587.25 EGO26754.1 - 1e-35 123.3 0.1 2.1e-35 122.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGO26754.1 - 2e-19 69.8 4.8 2e-19 69.8 4.8 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Hexapep PF00132.24 EGO26755.1 - 1.3e-08 34.2 20.9 2.8e-07 30.0 2.5 4.5 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO26755.1 - 0.00028 20.5 1.1 0.00028 20.5 1.1 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGO26755.1 - 0.0029 16.6 0.1 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 L-fucokinase Retrotran_gag_2 PF14223.6 EGO26756.1 - 7.5e-07 28.9 0.1 1e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Plavaka PF18759.1 EGO26758.1 - 1.2e-121 405.9 0.0 1.8e-121 405.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 EGO26758.1 - 0.0058 17.4 2.0 0.046 14.6 2.0 2.7 1 0 0 1 1 1 1 C2H2-type zinc finger DUF1771 PF08590.10 EGO26759.1 - 0.044 14.2 1.1 0.067 13.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_6 PF15288.6 EGO26759.1 - 0.051 13.4 0.9 0.91 9.4 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO26759.1 - 0.057 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO26759.1 - 0.095 12.5 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger DUF4718 PF15842.5 EGO26759.1 - 0.14 11.9 0.5 0.17 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) gag_pre-integrs PF13976.6 EGO26760.1 - 7.4e-11 41.7 0.6 1.2e-10 41.0 0.6 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain LPG_synthase_TM PF03706.13 EGO26761.1 - 0.00052 19.6 2.0 0.0007 19.2 2.0 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF4229 PF14012.6 EGO26761.1 - 0.048 13.7 0.1 0.048 13.7 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) MARVEL PF01284.23 EGO26761.1 - 0.057 13.5 0.2 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF4131 PF13567.6 EGO26761.1 - 0.87 9.2 3.2 4.5 6.9 3.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Ribonuc_2-5A PF06479.12 EGO26765.1 - 6.2e-46 155.7 0.1 1.3e-45 154.7 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EGO26765.1 - 3.7e-38 131.4 0.0 1.2e-29 103.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26765.1 - 2.7e-18 66.2 0.0 1.8e-17 63.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO26765.1 - 1.1e-05 24.4 0.0 3.6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 EGO26765.1 - 0.00043 19.9 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 EGO26765.1 - 0.0024 17.7 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.14 EGO26765.1 - 0.0042 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2486 PF10667.9 EGO26765.1 - 0.036 14.3 3.1 0.066 13.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) APH PF01636.23 EGO26765.1 - 0.073 13.0 0.0 0.3 11.0 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Aldedh PF00171.22 EGO26766.1 - 4.4e-117 391.4 0.0 5.6e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cas_Csy4 PF09618.10 EGO26767.1 - 0.14 12.3 3.5 0.13 12.4 0.6 2.3 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Csy4) zf_CCCH_4 PF18345.1 EGO26768.1 - 1.1e-07 31.7 23.3 0.00067 19.6 0.2 5.3 4 2 0 4 4 4 3 Zinc finger domain Torus PF16131.5 EGO26768.1 - 3.2e-07 31.0 11.5 0.016 15.9 0.1 3.8 3 1 1 4 4 4 3 Torus domain zf-CCCH PF00642.24 EGO26768.1 - 8.5e-07 28.7 1.2 8.5e-07 28.7 1.2 4.9 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGO26768.1 - 7.3e-06 26.3 32.1 0.0065 16.9 3.8 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGO26768.1 - 0.00058 19.6 10.3 0.011 15.5 4.8 4.9 5 1 0 5 5 5 3 CCCH-type zinc finger bZIP_1 PF00170.21 EGO26771.1 - 0.0017 18.4 2.6 0.002 18.2 1.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor KASH_CCD PF14662.6 EGO26771.1 - 0.0017 18.2 1.5 0.0026 17.6 1.5 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EGO26771.1 - 0.0027 17.9 1.0 0.0027 17.9 1.0 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper Chibby PF14645.6 EGO26771.1 - 0.0028 18.1 1.3 0.0044 17.4 1.3 1.4 1 0 0 1 1 1 1 Chibby family Shugoshin_N PF07558.11 EGO26771.1 - 0.0042 16.9 1.4 0.015 15.1 0.9 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 EGO26771.1 - 0.014 15.9 1.8 0.014 15.9 1.8 2.1 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 EGO26771.1 - 0.016 15.9 1.4 0.023 15.3 1.2 1.4 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 EGO26771.1 - 0.018 14.8 2.9 0.024 14.4 2.3 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF2205 PF10224.9 EGO26771.1 - 0.12 12.3 2.5 4.8 7.2 0.4 2.6 3 0 0 3 3 3 0 Short coiled-coil protein Mto2_bdg PF12808.7 EGO26771.1 - 0.27 11.6 2.3 13 6.2 0.6 2.7 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DDE_1 PF03184.19 EGO26772.1 - 8.6e-08 32.0 0.0 1.4e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF316 PF03761.15 EGO26772.1 - 0.022 14.3 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Helicase_C PF00271.31 EGO26774.1 - 4.1e-18 65.7 0.0 2.4e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO26774.1 - 1.4e-12 47.7 0.0 2.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGO26774.1 - 0.00011 21.5 0.1 0.00022 20.5 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGO26774.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 EGO26774.1 - 0.0057 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer RcbX PF02341.15 EGO26774.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 RbcX protein Glucan_synthase PF02364.15 EGO26776.1 - 0 1319.9 0.0 0 1319.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGO26776.1 - 1.1e-41 142.1 0.1 3.7e-41 140.5 0.1 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NAD_binding_4 PF07993.12 EGO26777.1 - 1.7e-21 76.6 0.0 2.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein COesterase PF00135.28 EGO26777.1 - 5.8e-11 41.9 0.0 9.3e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family AMP-binding PF00501.28 EGO26777.1 - 9.4e-11 40.9 0.0 1.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EGO26777.1 - 0.0021 17.6 0.1 0.02 14.4 0.0 2.6 4 0 0 4 4 4 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO26777.1 - 0.027 14.8 0.1 0.35 11.3 0.0 2.5 2 0 0 2 2 2 0 Phosphopantetheine attachment site HNF-1A_C PF04813.12 EGO26777.1 - 0.029 15.2 5.6 6.7 7.6 0.1 3.7 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Peroxidase_2 PF01328.17 EGO26778.1 - 5.5e-49 167.2 0.0 7e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Yip1 PF04893.17 EGO26779.1 - 1.3e-07 31.6 21.8 1.7e-07 31.1 21.8 1.3 1 0 0 1 1 1 1 Yip1 domain AA_permease_2 PF13520.6 EGO26780.1 - 3.1e-44 151.5 41.6 4.3e-44 151.0 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease TraL PF07178.11 EGO26780.1 - 0.034 14.6 1.2 0.034 14.6 1.2 3.2 3 0 0 3 3 3 0 TraL protein ThiF PF00899.21 EGO26781.1 - 1.4e-38 132.6 0.0 2.1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGO26781.1 - 4.7e-06 26.9 1.0 0.00013 22.3 1.0 2.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGO26781.1 - 0.0036 17.7 0.1 0.0085 16.5 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 EGO26781.1 - 0.052 13.1 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EGO26781.1 - 0.069 12.8 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Peptidase_S10 PF00450.22 EGO26782.1 - 5.8e-92 309.3 1.1 7e-92 309.0 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lyase_1 PF00206.20 EGO26783.1 - 2.3e-06 27.2 0.0 2.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Lyase Glyco_hydro_5_C PF18564.1 EGO26784.1 - 3.3e-24 85.2 0.1 6.7e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EGO26784.1 - 1.5e-15 57.3 0.0 1.5e-09 37.7 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) NACHT PF05729.12 EGO26785.1 - 6.3e-08 32.7 0.0 2.9e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGO26785.1 - 7.3e-05 23.2 0.0 0.00024 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGO26785.1 - 0.041 13.5 0.0 8 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGO26785.1 - 0.065 13.7 0.0 0.29 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO26785.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TauD PF02668.16 EGO26787.1 - 1.4e-47 162.7 3.9 1.4e-47 162.7 3.9 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGO26787.1 - 1e-12 48.5 0.1 6.9e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF971) MaoC_dehydratas PF01575.19 EGO26788.1 - 4.9e-28 97.2 0.0 1e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGO26788.1 - 1.2e-10 41.6 0.0 1.3e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase APH PF01636.23 EGO26789.1 - 1.8e-12 47.7 0.0 4.5e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGO26789.1 - 0.035 13.0 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Hexokinase_2 PF03727.16 EGO26790.1 - 8.5e-83 277.4 0.0 1.1e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGO26790.1 - 5.3e-69 232.1 0.0 8.1e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Ribosomal_L14 PF00238.19 EGO26791.1 - 1.4e-45 154.3 3.2 1.6e-45 154.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ATP-synt PF00231.19 EGO26792.1 - 1.1e-82 277.9 6.5 1.3e-82 277.7 6.5 1.0 1 0 0 1 1 1 1 ATP synthase eIF-5_eIF-2B PF01873.17 EGO26793.1 - 1.9e-41 140.6 0.0 3.6e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EGO26793.1 - 0.001 18.6 0.2 0.0023 17.4 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.12 EGO26793.1 - 0.1 12.4 0.1 19 5.1 0.0 2.5 2 0 0 2 2 2 0 HypF finger CAP_N PF01213.19 EGO26793.1 - 0.11 12.0 2.3 0.17 11.3 2.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Arc_trans_TRASH PF08394.10 EGO26793.1 - 1.6 9.1 4.6 15 6.0 0.0 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain DUF1754 PF08555.10 EGO26793.1 - 4.3 8.2 16.5 0.59 11.0 6.0 3.0 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) WD40 PF00400.32 EGO26794.1 - 9.2e-23 80.1 1.6 0.0016 19.2 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26794.1 - 1.7e-12 47.4 0.0 0.00013 22.2 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO26794.1 - 0.00019 21.4 0.0 0.096 12.6 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EGO26794.1 - 0.0022 17.1 0.0 1.3 8.0 0.0 2.8 3 0 0 3 3 3 2 Coatomer WD associated region Ge1_WD40 PF16529.5 EGO26794.1 - 0.032 13.2 0.0 3.9 6.3 0.0 2.9 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO26794.1 - 0.075 13.0 0.3 9.6 6.3 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 EGO26794.1 - 0.19 11.8 0.0 1.3 9.1 0.0 2.5 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup54 PF13874.6 EGO26796.1 - 6.4e-08 32.8 0.8 9.4e-07 29.0 0.1 2.0 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Ribosomal_L27e PF01777.18 EGO26797.1 - 1.1e-36 125.0 1.4 1.7e-36 124.4 1.4 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGO26797.1 - 0.015 15.3 0.1 0.042 13.8 0.1 1.8 1 0 0 1 1 1 0 KOW motif zf-CCHC PF00098.23 EGO26799.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO26799.1 - 0.0079 16.0 0.6 0.012 15.4 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO26799.1 - 0.014 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain Retrotrans_gag PF03732.17 EGO26801.1 - 2.3e-06 27.8 2.8 2.3e-06 27.8 2.8 2.2 2 2 1 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO26801.1 - 0.0055 16.6 0.2 0.012 15.5 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) M64_N PF16217.5 EGO26801.1 - 0.012 15.2 0.4 0.039 13.5 0.2 2.0 1 1 1 2 2 2 0 Peptidase M64 N-terminus Hydrophobin PF01185.18 EGO26802.1 - 1.5e-25 89.6 9.0 2e-25 89.2 9.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin PGAP1 PF07819.13 EGO26804.1 - 1.3e-06 28.3 0.1 3.6e-06 26.9 0.1 1.8 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO26804.1 - 7e-06 26.8 1.7 9.6e-06 26.4 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGO26804.1 - 0.00028 21.1 0.2 0.00062 19.9 0.2 1.6 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 EGO26804.1 - 0.00067 19.2 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGO26804.1 - 0.0007 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 EGO26804.1 - 0.0057 16.2 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 EGO26804.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 EGO26804.1 - 0.048 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.12 EGO26804.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) NARP1 PF12569.8 EGO26804.1 - 0.81 8.5 5.4 1.7 7.5 5.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_POL_M_15KD PF02150.16 EGO26805.1 - 4.8e-12 45.5 1.0 4.8e-12 45.5 1.0 3.4 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EGO26805.1 - 8.5e-12 44.7 1.3 8.5e-12 44.7 1.3 2.7 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) zf_UBZ PF18439.1 EGO26805.1 - 0.00078 19.0 4.6 1.8 8.2 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 EGO26805.1 - 0.004 17.5 0.2 0.004 17.5 0.2 2.0 2 1 0 2 2 2 1 Restriction alleviation protein Lar Elf1 PF05129.13 EGO26805.1 - 0.014 15.4 7.1 0.032 14.3 0.7 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like RecR PF02132.15 EGO26805.1 - 0.051 13.1 0.5 0.051 13.1 0.5 3.0 3 0 0 3 3 3 0 RecR protein zf-RRN7 PF11781.8 EGO26805.1 - 0.064 13.0 5.8 0.98 9.2 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GFA PF04828.14 EGO26805.1 - 0.1 13.0 5.4 4 7.8 0.7 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.10 EGO26805.1 - 0.16 12.1 8.4 3.8 7.7 0.2 3.4 4 0 0 4 4 4 0 Zinc ribbon domain DZR PF12773.7 EGO26805.1 - 0.31 11.1 10.7 3.4 7.8 1.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon DUF3268 PF11672.8 EGO26805.1 - 0.38 11.1 0.2 0.38 11.1 0.2 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain eIF-5_eIF-2B PF01873.17 EGO26805.1 - 0.56 10.1 5.6 1.7 8.6 0.6 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-ACC PF17848.1 EGO26805.1 - 0.69 10.0 10.6 21 5.3 0.2 4.2 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain UPF0547 PF10571.9 EGO26805.1 - 0.73 10.0 0.1 0.73 10.0 0.1 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 EGO26805.1 - 1.1 8.8 12.7 0.69 9.4 0.4 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Rpr2 PF04032.16 EGO26805.1 - 1.5 9.1 6.5 10 6.5 6.5 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.6 EGO26805.1 - 1.9 8.3 13.3 1.1 9.0 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain HNH_5 PF14279.6 EGO26805.1 - 1.9 8.4 7.6 5.7 6.9 0.0 3.0 3 1 0 3 3 3 0 HNH endonuclease Prim_Zn_Ribbon PF08273.12 EGO26805.1 - 2.6 8.4 9.3 0.43 10.9 1.9 2.8 3 1 0 3 3 2 0 Zinc-binding domain of primase-helicase zinc_ribbon_4 PF13717.6 EGO26805.1 - 3.4 7.7 9.3 3.4 7.7 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EGO26805.1 - 3.9 7.5 7.8 8.7 6.4 0.5 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon C1_1 PF00130.22 EGO26805.1 - 7.9 6.5 10.1 0.19 11.7 0.9 2.5 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ABA_GPCR PF12430.8 EGO26806.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor BTB PF00651.31 EGO26807.1 - 2.4e-09 37.4 0.0 3.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HABP4_PAI-RBP1 PF04774.15 EGO26808.1 - 0.00015 22.6 1.5 0.00022 22.1 1.5 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Pyr_redox_3 PF13738.6 EGO26809.1 - 1e-22 80.8 0.0 3e-19 69.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO26809.1 - 2.1e-17 63.3 0.0 7.7e-08 31.9 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGO26809.1 - 1.1e-15 57.0 0.1 6.5e-15 54.5 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 EGO26809.1 - 3.7e-09 37.0 0.6 0.00016 22.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO26809.1 - 2.4e-08 33.5 0.0 9.4e-06 25.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 EGO26809.1 - 1.1e-06 28.2 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EGO26809.1 - 3.5e-05 23.2 0.1 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 EGO26809.1 - 4.2e-05 23.5 0.1 0.13 12.1 0.0 2.5 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EGO26809.1 - 9e-05 22.2 0.4 0.077 12.6 0.1 3.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EGO26809.1 - 0.00039 19.6 0.2 0.0035 16.5 0.0 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGO26809.1 - 0.0016 18.6 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EGO26809.1 - 0.0017 18.4 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EGO26809.1 - 0.01 14.6 0.2 0.33 9.6 0.0 3.0 4 0 0 4 4 4 0 HI0933-like protein XdhC_C PF13478.6 EGO26809.1 - 0.015 15.8 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 EGO26809.1 - 0.016 15.5 0.1 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.15 EGO26809.1 - 0.02 15.1 0.0 7.7 6.7 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGO26809.1 - 0.036 13.7 0.0 0.22 11.2 0.0 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGO26809.1 - 0.055 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EGO26809.1 - 0.074 12.3 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EGO26809.1 - 0.074 12.1 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO26809.1 - 0.17 10.9 0.0 0.39 9.7 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thaumatin PF00314.17 EGO26810.1 - 3.1e-67 226.4 17.4 3.5e-67 226.2 17.4 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EGO26810.1 - 9.8e-05 21.8 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Beta-1,3-glucanase PRR18 PF15671.5 EGO26810.1 - 5.6 6.8 7.2 0.13 12.2 0.6 1.5 2 0 0 2 2 2 0 Proline-rich protein family 18 Amidase PF01425.21 EGO26812.1 - 1.4e-74 251.7 0.0 5.6e-73 246.4 0.0 2.0 1 1 0 1 1 1 1 Amidase zf-NOSIP PF15906.5 EGO26813.1 - 6.7e-13 48.6 0.5 1.6e-12 47.4 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 EGO26813.1 - 1.4e-06 28.1 21.6 0.0038 17.0 10.8 2.8 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO26813.1 - 4.2e-06 26.7 15.2 0.002 18.1 1.5 3.0 2 1 0 2 2 2 2 RING-type zinc-finger Rtf2 PF04641.12 EGO26813.1 - 2.5e-05 23.8 12.8 0.0013 18.1 1.2 2.7 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 EGO26813.1 - 2.7e-05 24.4 20.2 0.015 15.6 10.4 2.6 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 EGO26813.1 - 8.1e-05 22.4 21.6 0.03 14.2 3.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO26813.1 - 9.2e-05 22.3 22.0 0.00013 21.8 8.8 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO26813.1 - 0.00029 20.6 21.6 0.025 14.4 3.5 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO26813.1 - 0.0028 17.5 23.8 0.05 13.5 11.1 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGO26813.1 - 0.29 11.3 17.9 0.11 12.7 1.5 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF3039 PF11238.8 EGO26813.1 - 0.37 10.6 3.3 0.19 11.5 0.3 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3039) zinc-ribbons_6 PF07191.12 EGO26813.1 - 2.7 8.1 12.9 9.6 6.3 4.5 2.7 2 1 1 3 3 3 0 zinc-ribbons zf-C3HC4_5 PF17121.5 EGO26813.1 - 5 7.1 13.3 0.25 11.3 6.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_31 PF01055.26 EGO26814.1 - 1e-88 298.5 6.2 1.4e-88 298.0 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGO26814.1 - 0.0078 16.5 0.0 0.023 15.0 0.0 1.9 1 1 0 1 1 1 1 Galactose mutarotase-like EIF_2_alpha PF07541.12 EGO26816.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Cellulase PF00150.18 EGO26817.1 - 9.1e-09 35.1 0.7 4.9e-08 32.7 0.7 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AIM5 PF17050.5 EGO26818.1 - 9e-05 23.2 0.0 0.00012 22.8 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DUF543 PF04418.12 EGO26819.1 - 1.1e-28 99.0 0.1 1.2e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) F-box-like PF12937.7 EGO26820.1 - 8.5e-09 35.2 0.5 2.7e-07 30.4 0.1 2.6 2 0 0 2 2 2 2 F-box-like COesterase PF00135.28 EGO26821.1 - 2.5e-77 260.9 0.0 3.6e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO26821.1 - 0.0029 17.5 0.0 0.026 14.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO26821.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Myb_Cef PF11831.8 EGO26822.1 - 1.4e-61 208.1 1.9 1.4e-61 208.1 1.9 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGO26822.1 - 1.5e-18 66.7 12.3 9.3e-11 41.7 1.3 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO26822.1 - 2.9e-17 62.6 2.8 3.3e-12 46.4 2.9 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Velvet PF11754.8 EGO26823.1 - 2.3e-38 132.6 0.0 3.8e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor PHD PF00628.29 EGO26824.1 - 0.11 12.4 2.3 1.1 9.2 1.4 2.3 2 0 0 2 2 2 0 PHD-finger TB2_DP1_HVA22 PF03134.19 EGO26825.1 - 2.3e-10 40.2 1.2 3.7e-10 39.6 1.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Fungal_trans PF04082.18 EGO26826.1 - 2e-14 53.3 0.0 4.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO26826.1 - 0.00027 21.0 14.9 0.00053 20.1 14.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4743 PF15916.5 EGO26827.1 - 1.4e-06 28.3 0.0 0.00048 20.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NAD_binding_6 PF08030.12 EGO26828.1 - 3.5e-37 127.9 0.0 6.4e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO26828.1 - 9.5e-23 80.4 0.0 2e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGO26828.1 - 1.8e-18 66.9 12.8 1.8e-18 66.9 12.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EGO26828.1 - 0.098 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyco_hydro_28 PF00295.17 EGO26829.1 - 5.6e-38 130.8 0.0 1.1e-37 129.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 His_Phos_2 PF00328.22 EGO26830.1 - 0.0052 16.2 2.2 1.8 7.9 0.2 3.3 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 EGO26831.1 - 0.00023 20.6 0.1 0.042 13.2 0.0 2.8 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) CSN7a_helixI PF18392.1 EGO26831.1 - 0.35 10.8 1.0 0.63 10.0 1.0 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain VIT1 PF01988.19 EGO26832.1 - 2e-62 210.9 4.9 2.3e-62 210.7 4.9 1.1 1 0 0 1 1 1 1 VIT family SLATT_fungal PF18142.1 EGO26832.1 - 0.43 10.6 0.1 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF2013 PF09431.10 EGO26833.1 - 4.9e-57 192.0 0.3 1.1e-56 190.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Cucumopine_C PF18631.1 EGO26833.1 - 0.041 13.8 0.4 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain COX4 PF02936.14 EGO26833.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV CLN3 PF02487.17 EGO26834.1 - 9.5e-128 426.6 3.6 1.2e-127 426.3 3.6 1.1 1 0 0 1 1 1 1 CLN3 protein Vps26 PF03643.15 EGO26835.1 - 2.2e-129 430.3 3.1 2.5e-129 430.1 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGO26835.1 - 0.013 15.6 0.7 1.9 8.5 0.4 3.1 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Sof1 PF04158.14 EGO26838.1 - 8.3e-30 102.9 8.2 1.1e-29 102.5 7.0 1.8 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 EGO26838.1 - 8.4e-24 83.4 10.2 5e-07 30.3 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26838.1 - 0.0001 22.5 0.4 13 6.2 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO26838.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Plus-3 PF03126.18 EGO26839.1 - 8.6e-39 132.4 0.3 7e-38 129.5 0.1 2.7 3 1 0 3 3 3 1 Plus-3 domain AbiEi_3_N PF17194.4 EGO26839.1 - 0.081 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Paramyxo_NS_C PF02725.14 EGO26839.1 - 0.72 9.9 3.2 2.4 8.2 2.2 2.1 2 0 0 2 2 2 0 Non-structural protein C F-box-like PF12937.7 EGO26840.1 - 6.3e-05 22.8 1.7 0.00031 20.6 0.0 3.1 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 EGO26840.1 - 0.00031 20.6 0.6 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 1 F-box domain Methyltransf_3 PF01596.17 EGO26844.1 - 1.5e-37 128.9 0.1 1.8e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGO26844.1 - 8.2e-17 62.2 0.0 1.5e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO26844.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO26844.1 - 1.4e-07 32.1 0.0 2.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO26844.1 - 2e-06 28.3 0.0 4.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO26844.1 - 9.6e-06 25.5 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGO26844.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGO26844.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EGO26844.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGO26844.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CmcI PF04989.12 EGO26844.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Peptidase_S10 PF00450.22 EGO26845.1 - 5.4e-93 312.7 1.9 6.5e-93 312.4 1.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NS3_envE PF02723.14 EGO26845.1 - 0.034 14.2 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E AA_permease_2 PF13520.6 EGO26847.1 - 5.3e-54 183.7 54.8 7e-54 183.3 54.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO26847.1 - 1.3e-23 83.4 48.0 1.7e-23 83.0 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease COX2-transmemb PF09125.10 EGO26847.1 - 6.8 6.6 7.1 50 3.8 0.0 3.7 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane 2OG-FeII_Oxy PF03171.20 EGO26848.1 - 3.1e-16 59.7 0.0 6.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGO26848.1 - 1.5e-14 54.8 0.0 6.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal TauD PF02668.16 EGO26848.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Retrotrans_gag PF03732.17 EGO26849.1 - 1e-06 28.9 0.2 1e-06 28.9 0.2 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO26849.1 - 2.8e-05 24.0 0.4 6.1e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF5475 PF17569.2 EGO26850.1 - 0.11 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5475) MutS_V PF00488.21 EGO26851.1 - 4.6e-23 82.2 0.2 7.7e-23 81.5 0.2 1.3 1 0 0 1 1 1 1 MutS domain V DUF4618 PF15397.6 EGO26851.1 - 0.066 12.6 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) MutS_II PF05188.17 EGO26852.1 - 4e-17 62.8 0.1 1.5e-16 61.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain II MutS_III PF05192.18 EGO26852.1 - 2e-16 60.8 0.0 4.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain III BAH PF01426.18 EGO26853.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.9 1 1 0 1 1 1 0 BAH domain DIOX_N PF14226.6 EGO26855.1 - 2.5e-17 63.7 0.0 5.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO26855.1 - 7e-14 52.1 0.0 2e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3712 PF12505.8 EGO26856.1 - 0.05 13.9 0.0 1.2 9.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3712) GWT1 PF06423.12 EGO26857.1 - 8e-42 142.9 0.0 2.2e-41 141.4 0.0 1.8 1 0 0 1 1 1 1 GWT1 Ribosomal_L28 PF00830.19 EGO26858.1 - 1.8e-20 72.8 0.6 3.3e-20 72.0 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28 family DUF1764 PF08576.10 EGO26858.1 - 2.6 9.0 8.1 5.2 8.0 8.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) NT-C2 PF10358.9 EGO26859.1 - 1.7e-19 70.0 0.0 2.3e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins SET PF00856.28 EGO26865.1 - 3.6e-10 40.5 0.0 4.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 SET domain UPF0139 PF03669.13 EGO26867.1 - 0.00032 20.5 0.0 0.00041 20.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) zf-FCS PF06467.14 EGO26868.1 - 0.04 13.9 1.5 0.051 13.5 0.5 1.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif F-box PF00646.33 EGO26869.1 - 9.5e-05 22.2 0.3 0.00019 21.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO26869.1 - 0.0018 18.2 0.3 0.0054 16.6 0.1 1.9 1 1 1 2 2 2 1 F-box NPR3 PF03666.13 EGO26872.1 - 0.26 10.0 2.0 0.39 9.5 2.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 VHS PF00790.19 EGO26873.1 - 4.4e-25 88.2 0.0 9.5e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EGO26873.1 - 2.3e-09 37.5 3.0 3.5e-07 30.4 1.0 2.6 2 0 0 2 2 2 2 GAT domain ALMT PF11744.8 EGO26873.1 - 1.1 8.0 4.3 1.2 7.9 4.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF445 PF04286.12 EGO26873.1 - 2.2 8.0 10.5 3.3 7.4 10.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) M16C_assoc PF08367.11 EGO26873.1 - 6.1 5.9 9.3 11 5.0 9.3 1.4 1 0 0 1 1 1 0 Peptidase M16C associated CN_hydrolase PF00795.22 EGO26874.1 - 1.6e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WD40 PF00400.32 EGO26875.1 - 3e-26 91.1 17.1 1e-06 29.3 0.0 7.6 6 2 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26875.1 - 0.00028 21.1 0.0 6.6 7.1 0.0 4.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO26875.1 - 0.041 13.2 0.0 0.095 12.0 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 EGO26876.1 - 3.2e-37 125.9 14.3 9.2e-11 42.1 0.2 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO26876.1 - 1.7e-15 57.1 0.4 0.043 14.1 0.0 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO26876.1 - 1.9e-07 30.4 4.5 0.053 12.5 0.1 4.0 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein potato_inhibit PF00280.18 EGO26876.1 - 4.8e-05 23.9 0.0 7.9 7.2 0.0 3.9 4 0 0 4 4 4 2 Potato inhibitor I family PD40 PF07676.12 EGO26876.1 - 0.0019 18.1 0.9 4.5 7.3 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EGO26876.1 - 0.0022 16.7 0.1 1.4 7.5 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Fibrinogen_aC PF12160.8 EGO26876.1 - 0.0083 15.9 1.3 2.2 8.2 0.0 3.4 1 1 3 4 4 4 2 Fibrinogen alpha C domain Gmad1 PF10647.9 EGO26876.1 - 0.01 15.6 5.4 4.6 6.9 0.1 3.4 1 1 3 4 4 4 0 Lipoprotein LpqB beta-propeller domain Robl_LC7 PF03259.17 EGO26876.1 - 0.014 15.2 0.2 7.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Roadblock/LC7 domain MFS_1 PF07690.16 EGO26878.1 - 1.8e-18 66.6 16.5 1.8e-18 66.6 16.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 EGO26878.1 - 1.8e-06 26.9 0.0 1.9e-05 23.5 0.0 2.4 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 EGO26878.1 - 0.00039 19.4 12.5 0.0014 17.6 12.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter PDR_assoc PF08370.11 EGO26878.1 - 0.22 11.3 2.1 9.1 6.1 0.2 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated PIRT PF15099.6 EGO26878.1 - 0.87 9.2 2.8 19 4.8 0.5 3.5 3 1 0 3 3 3 0 Phosphoinositide-interacting protein family Iso_dh PF00180.20 EGO26879.1 - 2e-72 244.2 0.0 2.5e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHFR_2 PF06442.11 EGO26879.1 - 0.098 12.5 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase PNP_UDP_1 PF01048.20 EGO26880.1 - 4.5e-41 140.6 0.1 6.1e-41 140.2 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily ADH_zinc_N PF00107.26 EGO26883.1 - 9.9e-22 77.3 0.2 1.7e-21 76.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO26883.1 - 5.8e-19 68.0 0.0 1.2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGO26883.1 - 9.7e-08 33.1 0.0 2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 EGO26885.1 - 4.8e-73 245.8 0.0 7.5e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26885.1 - 8.5e-33 113.7 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO26885.1 - 6.7e-06 25.1 0.0 1.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO26885.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO26885.1 - 0.0013 18.1 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_N PF09379.10 EGO26885.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 FERM N-terminal domain APH PF01636.23 EGO26885.1 - 0.067 13.1 0.1 0.22 11.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S15 PF00312.22 EGO26885.1 - 1.1 9.5 3.3 0.59 10.4 1.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S15 DUF3444 PF11926.8 EGO26887.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) RTA1 PF04479.13 EGO26888.1 - 4e-61 206.2 3.2 6.2e-61 205.6 3.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Prominin PF05478.11 EGO26888.1 - 0.17 9.8 0.1 0.22 9.4 0.1 1.1 1 0 0 1 1 1 0 Prominin DAO PF01266.24 EGO26889.1 - 1.7e-61 208.8 0.6 2e-61 208.5 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO26889.1 - 6.7e-05 22.3 0.0 0.013 14.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO26889.1 - 7.2e-05 22.9 0.2 0.00018 21.7 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 EGO26889.1 - 7.5e-05 22.2 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox PF00070.27 EGO26889.1 - 0.00041 20.9 0.0 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGO26889.1 - 0.00049 19.1 0.2 0.0054 15.6 0.2 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EGO26889.1 - 0.0011 19.0 0.1 0.035 14.1 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGO26889.1 - 0.0094 15.1 0.1 0.27 10.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 EGO26889.1 - 0.021 15.1 0.1 0.22 11.8 0.1 2.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EGO26889.1 - 0.054 12.7 0.1 0.09 12.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Spermine_synth PF01564.17 EGO26889.1 - 0.22 10.9 0.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Herpes_ICP4_C PF03585.14 EGO26890.1 - 0.07 11.9 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region WH1 PF00568.23 EGO26891.1 - 1.8e-12 47.2 1.5 4.9e-10 39.3 0.7 2.1 2 0 0 2 2 2 2 WH1 domain PBD PF00786.28 EGO26891.1 - 0.0029 17.9 0.2 0.0055 17.0 0.2 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain DCP1 PF06058.13 EGO26891.1 - 0.051 13.5 0.0 0.087 12.8 0.0 1.4 1 1 0 1 1 1 0 Dcp1-like decapping family Pyr_redox_2 PF07992.14 EGO26892.1 - 4.4e-44 150.9 0.0 5.4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO26892.1 - 2.5e-10 40.8 0.0 4e-09 36.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO26892.1 - 0.063 12.5 0.3 2.4 7.3 0.1 2.6 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO26892.1 - 0.13 11.3 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.25 EGO26893.1 - 5.4e-34 117.8 0.0 4.1e-33 114.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26893.1 - 2.5e-18 66.3 0.0 1.2e-08 34.6 0.1 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO26893.1 - 0.00011 21.6 0.0 0.0009 18.6 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGO26893.1 - 0.0049 16.8 0.9 0.013 15.4 0.1 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Cupin_2 PF07883.11 EGO26894.1 - 5.6e-07 29.2 0.1 9.1e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGO26894.1 - 1e-05 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 EGO26894.1 - 0.0063 16.3 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EGO26894.1 - 0.014 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 EGO26894.1 - 0.031 14.5 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_3 PF05899.12 EGO26894.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SYF2 PF08231.12 EGO26895.1 - 1.5e-63 214.0 6.5 1.5e-63 214.0 6.5 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Smg4_UPF3 PF03467.15 EGO26896.1 - 1.1e-46 159.0 0.3 1.1e-46 159.0 0.3 2.4 2 1 0 2 2 2 1 Smg-4/UPF3 family MFS_1 PF07690.16 EGO26897.1 - 9.5e-24 84.0 28.8 4e-17 62.2 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 EGO26899.1 - 6.3e-06 26.3 0.2 1.3e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Herpes_UL56 PF04534.12 EGO26899.1 - 0.036 13.5 0.3 0.092 12.2 0.3 1.6 1 0 0 1 1 1 0 Herpesvirus UL56 protein TIMELESS PF04821.14 EGO26900.1 - 1.4e-79 267.2 0.0 7e-79 265.0 0.0 2.3 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EGO26900.1 - 8.6e-17 61.5 0.1 8.6e-17 61.5 0.1 3.2 2 1 0 3 3 3 1 Timeless protein C terminal region Polysacc_synt_4 PF04669.13 EGO26900.1 - 2.5e-16 59.8 0.2 6e-15 55.3 0.2 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis bZIP_1 PF00170.21 EGO26902.1 - 3.3e-05 23.9 8.0 0.0014 18.7 2.7 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 EGO26902.1 - 3.7e-05 23.7 10.3 0.00049 20.1 0.2 2.5 3 0 0 3 3 3 2 Basic region leucine zipper RolB_RolC PF02027.17 EGO26902.1 - 0.0031 17.2 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 RolB/RolC glucosidase family YabA PF06156.13 EGO26902.1 - 0.0041 17.7 0.1 0.0097 16.5 0.1 1.7 1 0 0 1 1 1 1 Initiation control protein YabA NYD-SP28_assoc PF14775.6 EGO26902.1 - 0.013 15.6 5.6 0.022 14.9 1.5 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain KASH_CCD PF14662.6 EGO26902.1 - 0.063 13.1 1.5 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 EGO26902.1 - 0.069 13.5 1.6 0.19 12.1 0.3 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 EGO26902.1 - 0.09 12.9 2.2 0.32 11.1 1.4 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 EGO26902.1 - 0.59 10.0 6.3 0.68 9.8 3.8 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 EGO26902.1 - 1.7 8.4 8.2 1.1 9.1 1.0 2.3 1 1 1 2 2 2 0 Septum formation initiator TAL_FSA PF00923.19 EGO26903.1 - 8.8e-17 61.4 0.0 5.4e-13 48.9 0.0 2.3 1 1 1 2 2 2 2 Transaldolase/Fructose-6-phosphate aldolase AA_permease PF00324.21 EGO26904.1 - 3.3e-122 408.5 46.6 4.1e-122 408.2 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO26904.1 - 2.1e-30 105.9 51.0 4.2e-30 104.9 50.8 1.5 1 1 0 1 1 1 1 Amino acid permease TMEMspv1-c74-12 PF11044.8 EGO26904.1 - 0.14 12.1 1.5 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Hydrolase_6 PF13344.6 EGO26905.1 - 5.8e-29 100.2 0.0 1.4e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO26905.1 - 1.1e-18 67.1 0.0 2.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGO26905.1 - 5.6e-10 39.9 0.0 1.5e-09 38.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO26905.1 - 9.3e-06 25.8 0.0 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGO26905.1 - 0.012 15.2 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ribosomal_L34e PF01199.18 EGO26907.1 - 4.1e-43 145.6 3.7 5.6e-43 145.2 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 EGO26907.1 - 0.27 11.2 3.5 2.4 8.2 0.4 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Tetraspanin PF00335.20 EGO26908.1 - 0.26 11.0 10.8 0.14 11.9 7.6 1.7 1 1 1 2 2 2 0 Tetraspanin family SpoIIM PF01944.17 EGO26908.1 - 7.5 6.6 11.1 0.38 10.8 0.2 3.1 4 0 0 4 4 4 0 Stage II sporulation protein M Ribosomal_L31e PF01198.19 EGO26909.1 - 2.3e-33 114.3 0.1 2.3e-33 114.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L31e CAP59_mtransfer PF11735.8 EGO26910.1 - 3e-70 236.7 0.1 3.9e-70 236.3 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 WW PF00397.26 EGO26912.1 - 2.5e-08 33.8 8.0 7.1e-08 32.4 8.0 1.8 1 0 0 1 1 1 1 WW domain Usp PF00582.26 EGO26913.1 - 3.4e-14 53.5 0.1 4.9e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family Josephin PF02099.17 EGO26914.1 - 0.0032 17.6 0.0 0.004 17.3 0.0 1.0 1 0 0 1 1 1 1 Josephin Terminase_6C PF17289.2 EGO26914.1 - 0.058 13.5 0.1 0.068 13.3 0.1 1.1 1 0 0 1 1 1 0 Terminase RNaseH-like domain RNase_PH PF01138.21 EGO26916.1 - 5.7e-28 98.1 0.1 1.2e-27 97.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGO26916.1 - 0.02 14.9 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ABC_tran PF00005.27 EGO26917.1 - 4.4e-34 117.9 0.0 7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGO26917.1 - 6.8e-08 32.2 0.1 6.1e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGO26917.1 - 7.8e-06 26.4 0.1 1.7e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 EGO26917.1 - 8.4e-06 24.8 0.0 7.7e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 EGO26917.1 - 2e-05 24.4 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_membrane PF00664.23 EGO26917.1 - 0.00013 21.8 0.6 0.00018 21.2 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 EGO26917.1 - 0.00027 21.2 0.1 0.0025 18.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO26917.1 - 0.0004 20.7 0.8 0.31 11.3 0.1 2.6 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGO26917.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 EGO26917.1 - 0.0025 17.6 0.1 0.0095 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGO26917.1 - 0.0031 17.4 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGO26917.1 - 0.0032 17.4 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 EGO26917.1 - 0.0097 15.9 0.0 0.11 12.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGO26917.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EGO26917.1 - 0.012 15.0 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 EGO26917.1 - 0.014 15.0 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EGO26917.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EGO26917.1 - 0.019 15.4 0.0 5.5 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGO26917.1 - 0.042 13.0 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EGO26917.1 - 0.045 13.5 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EGO26917.1 - 0.048 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 EGO26917.1 - 0.063 12.9 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 EGO26917.1 - 0.08 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Mg_chelatase PF01078.21 EGO26917.1 - 0.13 11.7 0.0 0.66 9.3 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGO26917.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGO26917.1 - 0.27 10.9 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Con-6 PF10346.9 EGO26918.1 - 1.8e-35 120.7 5.8 3.4e-18 65.4 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 NuA4 PF09340.10 EGO26918.1 - 0.21 11.5 1.6 3.9 7.4 1.6 2.0 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Chitin_synth_2 PF03142.15 EGO26922.1 - 2.5e-235 782.1 0.2 4e-235 781.4 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGO26922.1 - 5.2e-137 457.9 0.0 2.5e-136 455.7 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EGO26922.1 - 6.5e-18 64.4 0.1 1.8e-17 63.0 0.1 1.8 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EGO26922.1 - 4.5e-09 36.3 0.2 7.6e-07 29.2 0.0 2.7 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EGO26922.1 - 2.6e-08 34.0 0.0 2.8e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGO26922.1 - 8.3e-08 32.4 3.2 8.3e-08 32.4 3.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO26922.1 - 0.0022 17.9 0.0 0.65 9.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_29 PF13555.6 EGO26922.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3543 PF12063.8 EGO26923.1 - 4.1e-31 108.3 0.2 1.2e-30 106.7 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EGO26925.1 - 2.1e-21 76.5 0.0 2.2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26925.1 - 1.6e-14 53.9 0.0 1.7e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_Me_trans PF04252.13 EGO26926.1 - 1.7e-81 272.6 0.0 1.9e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Aminotran_1_2 PF00155.21 EGO26927.1 - 3.1e-39 135.2 0.0 3.7e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO26927.1 - 0.022 13.3 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Thr_synth_N PF14821.6 EGO26929.1 - 4.6e-28 97.3 0.0 1.7e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EGO26929.1 - 3.2e-17 62.9 0.3 8e-16 58.3 0.3 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PfaD_N PF18328.1 EGO26929.1 - 0.15 12.0 0.1 0.42 10.6 0.1 1.8 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain FAD_binding_3 PF01494.19 EGO26930.1 - 1.3e-21 77.3 0.0 3.7e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO26930.1 - 2.4e-05 24.5 0.7 8.5e-05 22.7 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EGO26930.1 - 0.00016 20.7 0.9 0.014 14.3 0.2 2.8 2 1 1 3 3 3 1 Tryptophan halogenase DAO PF01266.24 EGO26930.1 - 0.0002 21.0 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO26930.1 - 0.0044 16.3 0.5 0.014 14.7 0.4 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO26930.1 - 0.031 13.5 0.2 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 EGO26930.1 - 0.064 12.3 0.0 0.14 11.2 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 EGO26930.1 - 0.066 12.3 2.3 0.11 11.6 2.3 1.3 1 0 0 1 1 1 0 FAD binding domain STAG PF08514.11 EGO26931.1 - 1.9e-36 124.4 0.6 1.3e-35 121.7 0.3 2.7 1 1 1 2 2 2 1 STAG domain HEAT_2 PF13646.6 EGO26931.1 - 2.4e-09 37.5 0.0 7.6e-06 26.2 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EGO26931.1 - 6.1e-05 22.9 0.8 9.9 6.7 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.25 EGO26935.1 - 3.5e-33 115.1 0.0 4.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO26935.1 - 2e-13 50.2 0.1 2.8e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO26935.1 - 6.8e-06 25.6 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO26935.1 - 0.00018 20.5 0.0 0.00025 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO26935.1 - 0.0011 18.4 0.2 0.0016 17.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO26935.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family bZIP_C PF12498.8 EGO26936.1 - 0.031 15.2 0.1 0.042 14.8 0.1 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal DHHA2 PF02833.14 EGO26938.1 - 2.8e-29 102.1 0.1 4.7e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EGO26938.1 - 2.9e-11 43.5 0.1 5e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 DHH family Complex1_LYR PF05347.15 EGO26939.1 - 2.2e-13 50.0 0.3 2.8e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO26939.1 - 0.099 13.4 0.1 0.11 13.2 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Urm1 PF09138.11 EGO26940.1 - 4.8e-34 116.6 0.0 1.2e-28 99.3 0.0 2.0 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGO26940.1 - 9.8e-05 22.9 0.0 0.00014 22.5 0.0 1.2 1 0 0 1 1 1 1 ThiS family FMN_dh PF01070.18 EGO26941.1 - 2.7e-103 345.7 0.0 4.1e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EGO26941.1 - 1.4e-06 28.0 0.4 2.1e-06 27.4 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EGO26941.1 - 3.5e-05 23.1 0.1 5.1e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGO26941.1 - 0.00019 20.6 0.4 0.00028 20.0 0.4 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EGO26941.1 - 0.00025 20.4 0.2 0.00071 18.9 0.1 1.7 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 EGO26941.1 - 0.029 13.7 0.7 0.33 10.2 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGO26941.1 - 0.13 11.7 0.6 0.57 9.6 0.5 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein Ribosomal_S30 PF04758.14 EGO26942.1 - 9.6e-31 105.8 7.0 1.1e-30 105.6 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pterin_bind PF00809.22 EGO26943.1 - 5.7e-60 203.0 0.0 8.3e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGO26943.1 - 3.8e-34 117.6 0.0 7.4e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EGO26943.1 - 1.8e-27 96.1 0.0 1.2e-13 51.6 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase TPR_14 PF13428.6 EGO26944.1 - 1.7e-07 31.5 3.0 0.0015 19.2 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO26944.1 - 2.4e-07 31.1 0.9 0.00087 19.7 1.6 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO26944.1 - 2.5e-07 31.2 0.4 3.4e-05 24.4 0.0 3.9 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO26944.1 - 2.3e-06 27.3 0.0 0.0014 18.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO26944.1 - 6.7e-06 25.7 0.5 0.0008 19.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO26944.1 - 0.00049 20.5 2.8 7.7 7.4 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO26944.1 - 0.00058 19.9 0.3 0.015 15.4 0.1 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO26944.1 - 0.00079 19.5 0.8 0.3 11.2 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO26944.1 - 0.0074 16.6 1.5 1.1 9.6 0.2 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO26944.1 - 0.012 15.3 0.6 0.16 11.7 0.2 2.9 3 0 0 3 3 3 0 TPR repeat CotJB PF12652.7 EGO26944.1 - 0.027 14.7 0.9 0.48 10.7 0.1 2.4 2 0 0 2 2 2 0 CotJB protein TPR_17 PF13431.6 EGO26944.1 - 0.038 14.4 0.1 0.74 10.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO26944.1 - 0.091 12.8 1.2 2.8 8.2 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Peptidase_S24 PF00717.23 EGO26945.1 - 1e-09 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Fungal_trans PF04082.18 EGO26947.1 - 7.8e-13 48.1 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 EGO26948.1 - 5.2e-29 101.3 28.2 8.7e-29 100.6 28.2 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RnlA_toxin PF15935.5 EGO26948.1 - 0.25 11.1 0.0 0.43 10.3 0.0 1.3 1 0 0 1 1 1 0 RNase LS, bacterial toxin GTP1_OBG PF01018.22 EGO26949.1 - 6.6e-42 142.7 1.2 9.5e-31 106.5 0.1 3.0 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 EGO26949.1 - 2e-19 69.7 0.0 3.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO26949.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGO26949.1 - 0.00064 19.3 0.1 0.059 12.9 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGO26949.1 - 0.00095 19.3 0.0 0.0048 17.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family cobW PF02492.19 EGO26949.1 - 0.0012 18.4 0.0 0.53 9.8 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 EGO26949.1 - 0.0027 17.2 0.2 0.86 9.0 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.27 EGO26949.1 - 0.033 14.7 0.1 0.095 13.2 0.1 1.7 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 EGO26949.1 - 0.4 10.6 2.8 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 POPLD PF08170.12 EGO26949.1 - 0.55 10.6 4.9 8.9 6.7 0.1 2.5 2 0 0 2 2 2 0 POPLD (NUC188) domain HLH PF00010.26 EGO26950.1 - 3.9e-12 45.9 0.0 7.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.6 EGO26950.1 - 0.047 13.9 5.5 0.15 12.3 2.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) MoCF_biosynth PF00994.24 EGO26951.1 - 8e-33 113.1 0.0 1.2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MCM PF00493.23 EGO26952.1 - 2.9e-95 317.6 0.0 4.3e-95 317.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO26952.1 - 5.7e-36 123.1 0.7 9.6e-36 122.4 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO26952.1 - 8.6e-29 99.8 1.4 2.3e-28 98.4 1.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO26952.1 - 1.3e-17 64.3 0.2 5.1e-17 62.4 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 EGO26952.1 - 7.3e-09 35.7 0.0 2.1e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGO26952.1 - 4.9e-07 29.3 0.0 0.0004 19.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGO26952.1 - 2.1e-05 24.4 0.0 0.00043 20.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO26952.1 - 0.0026 18.2 0.1 0.021 15.2 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EGO26952.1 - 0.0039 16.9 0.1 3.6 7.3 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain ORC_WH_C PF18137.1 EGO26953.1 - 1.2e-38 132.4 0.0 1.9e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EGO26953.1 - 3.6e-31 108.5 0.8 1.2e-30 106.8 0.8 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus GPI-anchored PF10342.9 EGO26954.1 - 2.4e-08 34.6 0.5 4.8e-08 33.7 0.5 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hist_deacetyl PF00850.19 EGO26955.1 - 3.9e-86 289.3 0.0 6.1e-86 288.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EGO26955.1 - 5e-35 120.9 0.0 7.1e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain CSN8_PSD8_EIF3K PF10075.9 EGO26956.1 - 4.2e-22 78.7 0.0 7e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 EGO26957.1 - 6.8e-40 136.6 1.3 1.4e-39 135.6 1.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGO26957.1 - 9.8e-14 51.7 2.0 1.9e-13 50.9 0.4 2.2 2 0 0 2 2 2 1 PCI domain PP2C PF00481.21 EGO26958.1 - 3.1e-26 92.6 0.0 9.3e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGO26958.1 - 6.3e-06 26.0 0.0 9.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Asn_synthase PF00733.21 EGO26959.1 - 1.1e-66 226.0 0.0 1.5e-66 225.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGO26959.1 - 2.2e-38 130.9 0.0 3.8e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGO26959.1 - 4.3e-30 104.6 0.0 1.2e-29 103.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGO26959.1 - 5.7e-06 26.0 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGO26959.1 - 0.023 13.8 0.0 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD synthase Abhydrolase_3 PF07859.13 EGO26960.1 - 1.1e-21 77.6 0.0 1.7e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO26960.1 - 1.7e-05 23.9 0.0 4.4e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EGO26960.1 - 0.11 13.0 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGO26960.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SepZ PF06066.11 EGO26961.1 - 0.17 12.1 1.9 10 6.4 0.0 2.7 1 1 1 2 2 2 0 SepZ Plavaka PF18759.1 EGO26963.1 - 3e-93 312.6 1.2 7e-48 163.5 0.0 3.2 1 1 2 3 3 3 3 Plavaka transposase zf-C2H2_4 PF13894.6 EGO26963.1 - 0.4 11.7 8.0 0.055 14.3 2.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CCHC PF00098.23 EGO26965.1 - 0.0022 18.0 4.1 0.0038 17.3 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26965.1 - 0.0071 16.6 0.3 0.018 15.3 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 EGO26965.1 - 1.9 8.4 3.8 3.6 7.5 3.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Sec_GG PF07549.14 EGO26966.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Retrotran_gag_2 PF14223.6 EGO26968.1 - 1e-10 41.4 0.3 1.5e-10 40.9 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO26968.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Isy1 PF06246.12 EGO26970.1 - 1.7e-92 309.6 0.0 3e-92 308.8 0.0 1.4 1 1 0 1 1 1 1 Isy1-like splicing family Sugar_tr PF00083.24 EGO26971.1 - 7.9e-110 367.8 26.1 9.2e-110 367.6 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO26971.1 - 1.8e-23 83.1 28.9 1.8e-23 83.1 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily N2227 PF07942.12 EGO26972.1 - 2.9e-97 325.1 0.0 5e-97 324.3 0.0 1.4 2 0 0 2 2 2 1 N2227-like protein Methyltransf_12 PF08242.12 EGO26972.1 - 0.0017 19.0 0.1 0.02 15.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO26972.1 - 0.003 17.4 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO26972.1 - 0.0043 17.7 0.0 0.14 12.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP2C PF00481.21 EGO26973.1 - 4e-26 92.2 0.0 1.4e-22 80.6 0.0 2.1 1 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGO26973.1 - 0.072 13.0 0.0 9 6.2 0.0 2.6 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Pkinase_Tyr PF07714.17 EGO26974.1 - 3.5e-43 147.7 0.0 4.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO26974.1 - 7.9e-41 140.2 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGO26974.1 - 2e-06 27.4 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO26974.1 - 0.0024 17.8 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO26974.1 - 0.0036 16.2 0.0 0.0069 15.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Glyco_transf_90 PF05686.12 EGO26975.1 - 3.4e-12 46.0 4.4 7.5e-11 41.6 4.4 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 Cauli_VI PF01693.16 EGO26975.1 - 0.0065 16.8 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin CBM46 PF18448.1 EGO26976.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain Molybdopterin PF00384.22 EGO26977.1 - 6.3e-70 236.3 0.0 4.2e-69 233.6 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EGO26977.1 - 2.3e-19 69.2 0.3 5.8e-19 67.9 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EGO26977.1 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 EGO26977.1 - 1.6e-16 60.7 0.4 3.7e-16 59.5 0.4 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 EGO26977.1 - 4.2e-08 33.0 0.6 4.2e-08 33.0 0.6 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EGO26977.1 - 0.1 12.5 1.1 4.8 7.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain TPP_enzyme_M PF00205.22 EGO26977.1 - 0.1 12.3 0.0 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ABC2_membrane PF01061.24 EGO26978.1 - 1.8e-73 246.4 51.9 1e-42 146.0 19.3 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EGO26978.1 - 2.4e-41 139.5 6.6 1.6e-34 117.6 0.1 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EGO26978.1 - 5.4e-37 127.4 0.0 1.7e-18 67.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 EGO26978.1 - 1.3e-12 48.1 1.7 1.5e-12 48.0 0.1 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGO26978.1 - 5.2e-07 29.7 0.0 9.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGO26978.1 - 7.3e-07 29.7 0.0 0.00079 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO26978.1 - 3.7e-05 24.0 0.0 0.02 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGO26978.1 - 4.5e-05 22.7 27.0 4.5e-05 22.7 27.0 3.7 3 2 0 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGO26978.1 - 7.8e-05 22.3 0.0 0.025 14.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGO26978.1 - 9.8e-05 22.0 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGO26978.1 - 0.00012 22.1 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 EGO26978.1 - 0.00048 20.2 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EGO26978.1 - 0.0012 19.4 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO26978.1 - 0.0015 18.7 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGO26978.1 - 0.014 15.9 0.1 0.033 14.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGO26978.1 - 0.015 15.0 0.3 0.43 10.3 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGO26978.1 - 0.023 14.9 0.1 0.14 12.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGO26978.1 - 0.026 14.3 0.1 0.74 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 EGO26978.1 - 0.038 14.0 0.1 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EGO26978.1 - 0.044 13.6 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF872 PF05915.12 EGO26978.1 - 0.065 13.4 0.6 0.24 11.6 0.0 2.4 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF872) Zeta_toxin PF06414.12 EGO26978.1 - 0.098 11.9 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EGO26978.1 - 0.11 13.0 0.0 4.1 7.8 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EGO26978.1 - 0.14 11.0 0.6 0.22 10.3 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 EGO26978.1 - 0.15 12.5 0.0 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 EGO26978.1 - 0.21 11.2 1.0 1.3 8.6 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dscam_C PF12355.8 EGO26979.1 - 0.041 14.8 1.3 0.084 13.8 0.2 1.8 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal adh_short_C2 PF13561.6 EGO26983.1 - 1.6e-58 198.0 1.3 2.1e-58 197.6 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO26983.1 - 1.1e-49 168.5 3.0 1.5e-49 168.1 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO26983.1 - 1.8e-18 67.1 0.4 5.1e-18 65.6 0.2 1.6 1 1 1 2 2 2 1 KR domain Glyco_tran_WecB PF03808.13 EGO26983.1 - 0.0006 19.8 0.1 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.21 EGO26983.1 - 0.0017 17.8 0.2 0.0026 17.3 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO26983.1 - 0.0096 15.4 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EGO26983.1 - 0.054 13.4 0.1 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4170 PF13773.6 EGO26983.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) F420_oxidored PF03807.17 EGO26983.1 - 0.18 12.4 1.1 4.6 7.9 0.1 2.8 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Cation_efflux PF01545.21 EGO26984.1 - 9.2e-06 25.5 2.2 2e-05 24.4 2.1 1.7 1 1 0 1 1 1 1 Cation efflux family OppC_N PF12911.7 EGO26984.1 - 0.23 11.4 3.2 1.7 8.7 1.1 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1772 PF08592.11 EGO26986.1 - 4.9 7.5 7.9 0.34 11.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) GMC_oxred_N PF00732.19 EGO26987.1 - 9.9e-57 192.6 0.0 1.7e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO26987.1 - 4.2e-33 114.9 0.0 8.8e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Nyv1_N PF09426.10 EGO26987.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Sugar_tr PF00083.24 EGO26988.1 - 1.6e-99 333.8 20.9 2.3e-99 333.3 20.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO26988.1 - 5.8e-22 78.1 37.2 6.4e-16 58.2 5.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO26989.1 - 1.1e-98 331.1 15.9 4e-98 329.2 15.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO26989.1 - 1.3e-24 86.8 27.3 5.8e-17 61.7 2.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO26989.1 - 0.0031 16.0 2.3 0.0031 16.0 2.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EGO26989.1 - 0.0054 15.2 5.5 0.016 13.6 2.4 2.3 2 0 0 2 2 2 1 Transmembrane secretion effector NADH_dehy_S2_C PF06444.11 EGO26989.1 - 0.014 15.9 0.1 0.034 14.6 0.1 1.7 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus zf-CCHC PF00098.23 EGO26992.1 - 0.002 18.1 4.1 0.0032 17.5 4.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO26992.1 - 0.0082 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DKNYY PF13644.6 EGO26992.1 - 0.069 13.9 0.6 0.14 12.9 0.6 1.4 1 0 0 1 1 1 0 DKNYY family zf-CCHC_2 PF13696.6 EGO26992.1 - 1.6 8.7 3.8 3.1 7.7 3.8 1.5 1 0 0 1 1 1 0 Zinc knuckle PTPA PF03095.15 EGO26994.1 - 9.2e-125 416.1 0.0 1.1e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein COG5 PF10392.9 EGO26995.1 - 0.037 14.2 1.2 0.11 12.7 0.3 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 RAP1 PF07218.11 EGO26995.1 - 0.037 12.3 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 EGO26995.1 - 0.04 13.3 0.6 0.044 13.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.18 EGO26995.1 - 0.049 13.4 4.3 0.26 11.1 0.9 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein DUF2299 PF10061.9 EGO26996.1 - 0.056 13.2 0.9 9.9 5.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) Plavaka PF18759.1 EGO27000.1 - 1.8e-71 241.0 0.3 3e-59 200.9 0.1 2.1 1 1 1 2 2 2 2 Plavaka transposase Myb_DNA-bind_3 PF12776.7 EGO27001.1 - 0.0002 22.3 0.0 0.00049 21.0 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO27001.1 - 0.008 16.5 0.0 0.05 14.0 0.0 2.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4939 PF16297.5 EGO27002.1 - 0.00029 20.7 0.1 0.00058 19.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Toprim_4 PF13662.6 EGO27002.1 - 0.027 14.9 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Toprim domain DUF4939 PF16297.5 EGO27003.1 - 0.00029 20.7 0.1 0.00058 19.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Toprim_4 PF13662.6 EGO27003.1 - 0.027 14.9 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Toprim domain CCDC53 PF10152.9 EGO27004.1 - 0.036 14.5 0.4 0.1 13.0 0.4 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex zf-CCHC_3 PF13917.6 EGO27004.1 - 0.15 12.0 3.6 0.47 10.4 3.6 1.8 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_2 PF13240.6 EGO27004.1 - 3.9 7.3 7.3 0.64 9.8 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DKNYY PF13644.6 EGO27005.1 - 0.0035 18.1 0.5 0.0044 17.8 0.5 1.1 1 0 0 1 1 1 1 DKNYY family DUF4939 PF16297.5 EGO27005.1 - 0.025 14.5 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DDE_1 PF03184.19 EGO27007.1 - 7.7e-10 38.7 7.1 8.2e-09 35.4 2.2 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGO27008.1 - 0.081 13.0 0.1 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Retrotrans_gag PF03732.17 EGO27010.1 - 0.00015 22.0 0.4 0.0016 18.6 0.0 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein Plavaka PF18759.1 EGO27012.1 - 3.8e-113 378.0 0.0 4.7e-113 377.7 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase RTC PF01137.21 EGO27014.1 - 0.025 13.8 0.0 0.053 12.7 0.0 1.4 1 1 0 2 2 2 0 RNA 3'-terminal phosphate cyclase Plavaka PF18759.1 EGO27015.1 - 2.4e-37 128.9 0.0 3e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase PIF1 PF05970.14 EGO27022.1 - 3.7e-06 26.3 0.9 1e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 PIF1-like helicase AAA_19 PF13245.6 EGO27022.1 - 0.0026 18.1 0.1 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO27022.1 - 0.0055 16.5 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AMP-binding PF00501.28 EGO27024.1 - 1.2e-58 198.7 0.0 2.2e-36 125.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGO27024.1 - 0.0038 18.2 0.0 0.0087 17.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DDE_1 PF03184.19 EGO27025.1 - 0.002 17.8 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 EGO27026.1 - 1.5e-06 28.4 0.0 6.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO27026.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 EGO27027.1 - 0.00026 21.6 0.0 0.00055 20.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO27027.1 - 0.0014 19.2 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO27027.1 - 0.077 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5475 PF17569.2 EGO27027.1 - 0.2 12.0 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5475) GMC_oxred_N PF00732.19 EGO27028.1 - 5.3e-64 216.4 0.0 6.7e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO27028.1 - 1.3e-31 110.0 0.0 2.7e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO27028.1 - 0.0002 20.5 0.0 0.00035 19.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Hydrophobin PF01185.18 EGO27029.1 - 2.4e-26 92.2 7.3 3.6e-26 91.6 7.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin AA_permease PF00324.21 EGO27031.1 - 4.4e-105 352.0 41.5 5.7e-105 351.7 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO27031.1 - 3.9e-30 105.0 44.7 8.5e-30 103.9 44.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO27032.1 - 1e-103 347.6 48.7 1.3e-103 347.2 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO27032.1 - 2.6e-24 85.9 52.3 3.2e-24 85.5 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease PhoLip_ATPase_C PF16212.5 EGO27033.1 - 1.7e-81 273.7 23.9 1.7e-81 273.7 23.9 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO27033.1 - 3.1e-24 84.4 6.1 1.3e-23 82.4 6.1 2.2 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGO27033.1 - 1.8e-12 47.2 0.0 5.7e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO27033.1 - 6.9e-12 46.1 1.2 1.3e-06 28.8 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO27033.1 - 3.5e-08 33.2 0.0 1.4e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGO27033.1 - 0.0056 16.5 0.5 0.016 15.0 0.2 1.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 EGO27034.1 - 7.6e-46 156.3 0.0 1.2e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EGO27034.1 - 0.00052 19.9 3.0 0.22 11.7 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO27034.1 - 0.00086 19.0 2.0 0.18 11.7 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat LnmK_N_HDF PF18238.1 EGO27034.1 - 0.13 12.0 0.1 0.54 10.0 0.1 1.9 2 0 0 2 2 2 0 LnmK N-terminal Hot Dog Fold domain TPR_11 PF13414.6 EGO27034.1 - 0.23 11.2 0.2 0.23 11.2 0.2 2.9 4 0 0 4 4 4 0 TPR repeat RhoGAP PF00620.27 EGO27037.1 - 7.1e-10 38.9 0.0 9.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Retrotran_gag_2 PF14223.6 EGO27040.1 - 1.8e-08 34.1 0.2 2.2e-08 33.9 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MAD PF05557.13 EGO27042.1 - 0.021 13.2 53.6 0.006 15.0 18.2 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein ApoO PF09769.9 EGO27042.1 - 2.8 7.9 12.6 0.97 9.4 2.9 3.4 3 1 0 3 3 3 0 Apolipoprotein O F-box-like PF12937.7 EGO27043.1 - 6e-06 26.0 2.0 1.7e-05 24.6 0.7 2.6 2 0 0 2 2 2 1 F-box-like Abhydrolase_1 PF00561.20 EGO27047.1 - 7.4e-19 68.4 0.3 2.7e-18 66.5 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO27047.1 - 6.6e-14 53.0 0.1 9.1e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO27047.1 - 1.1e-08 34.7 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EGO27047.1 - 7.8e-05 21.5 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family UNC45-central PF11701.8 EGO27048.1 - 8.6e-34 116.7 0.1 2.6e-33 115.2 0.1 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EGO27048.1 - 0.029 14.4 2.7 15 5.8 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGO27048.1 - 0.049 12.2 0.1 2.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region zf-CCHC_6 PF15288.6 EGO27049.1 - 0.0074 16.1 0.8 0.019 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle BUD22 PF09073.10 EGO27051.1 - 0.0018 17.7 12.3 0.0028 17.1 12.3 1.3 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 EGO27051.1 - 0.53 8.5 6.0 0.62 8.3 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Glypican PF01153.19 EGO27051.1 - 1 8.1 3.7 1.6 7.4 3.7 1.4 1 0 0 1 1 1 0 Glypican SDA1 PF05285.12 EGO27051.1 - 2 7.8 9.3 3.1 7.1 9.3 1.5 1 0 0 1 1 1 0 SDA1 DNA_binding_1 PF01035.20 EGO27052.1 - 5.8e-25 87.2 0.0 9.6e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Deltaretro_Tax PF05599.11 EGO27052.1 - 0.034 14.7 0.2 0.097 13.2 0.2 1.8 1 1 0 1 1 1 0 Deltaretrovirus Tax protein Ifi-6-16 PF06140.13 EGO27053.1 - 0.026 14.5 23.7 0.055 13.4 23.6 1.7 1 1 0 1 1 1 0 Interferon-induced 6-16 family Apolipoprotein PF01442.18 EGO27053.1 - 0.046 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1904 PF08921.11 EGO27055.1 - 0.099 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) DDE_3 PF13358.6 EGO27057.1 - 5.6e-12 45.6 0.0 1.9e-11 43.9 0.0 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF2183 PF09949.9 EGO27057.1 - 0.036 14.4 0.1 0.078 13.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Peptidase_S10 PF00450.22 EGO27058.1 - 2.7e-75 254.3 0.0 4.1e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase SNO PF01174.19 EGO27059.1 - 5.6e-47 160.0 0.0 9.3e-45 152.8 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGO27059.1 - 6.9e-09 35.6 0.0 9.9e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EGO27059.1 - 0.00095 19.0 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 EGO27059.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 EGO27059.1 - 0.015 15.1 0.1 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase class-I RRM_1 PF00076.22 EGO27061.1 - 2.3e-15 56.2 0.0 2.3e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO27061.1 - 2.6e-06 27.5 0.0 8.4e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif Ribosomal_L32p PF01783.23 EGO27064.1 - 1.7 8.9 8.8 0.9 9.8 6.3 1.8 2 0 0 2 2 2 0 Ribosomal L32p protein family Anoctamin PF04547.12 EGO27066.1 - 8.1e-103 344.7 0.0 1e-102 344.3 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Se-cys_synth_N PF12390.8 EGO27066.1 - 2.6 8.3 6.3 0.18 12.0 0.4 2.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal AAA_lid_3 PF17862.1 EGO27068.1 - 8.1e-12 44.7 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 AAA+ lid domain Suf PF05843.14 EGO27069.1 - 9.2e-77 258.9 0.0 8.2e-74 249.2 0.0 3.4 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGO27069.1 - 1e-11 44.6 6.8 0.092 13.6 0.0 7.8 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO27069.1 - 6.6e-08 32.9 1.9 0.015 15.8 0.2 4.7 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGO27069.1 - 0.0013 18.0 4.3 3.8 6.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO27069.1 - 0.0017 18.4 0.0 0.21 11.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO27069.1 - 0.0029 18.1 3.6 0.31 11.8 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat FTCD_C PF04961.12 EGO27069.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase TPR_17 PF13431.6 EGO27069.1 - 0.041 14.3 0.6 33 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat 7TMR-HDED PF07697.11 EGO27069.1 - 0.22 11.6 1.9 4.3 7.4 0.0 2.8 2 1 0 2 2 2 0 7TM-HD extracellular Glyco_hydro_85 PF03644.13 EGO27070.1 - 1.6e-85 287.2 0.0 2.3e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 bZIP_1 PF00170.21 EGO27072.1 - 0.0003 20.8 0.4 0.0003 20.8 0.4 2.4 3 0 0 3 3 3 1 bZIP transcription factor Herpes_BLRF2 PF05812.12 EGO27072.1 - 0.024 14.8 0.5 0.07 13.3 0.5 2.0 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 EGO27072.1 - 0.1 12.9 2.4 0.6 10.5 0.5 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 EGO27072.1 - 0.12 12.5 3.6 0.12 12.5 1.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper SOGA PF11365.8 EGO27072.1 - 0.24 12.6 3.9 0.34 12.1 0.1 2.5 2 1 0 2 2 2 0 Protein SOGA Golgin_A5 PF09787.9 EGO27072.1 - 2 7.8 10.5 0.057 12.9 1.7 2.1 2 1 0 2 2 2 0 Golgin subfamily A member 5 RFC1 PF08519.12 EGO27073.1 - 6e-58 195.5 0.0 1e-56 191.5 0.0 2.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EGO27073.1 - 1.6e-12 47.6 0.0 4.9e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EGO27073.1 - 4.9e-08 33.5 0.0 1.3e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGO27073.1 - 0.00072 19.5 0.1 0.0018 18.2 0.1 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EGO27073.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGO27073.1 - 0.088 12.7 0.7 0.68 9.8 0.3 2.2 1 1 1 2 2 2 0 NTPase AAA_assoc_2 PF16193.5 EGO27073.1 - 0.099 13.0 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain NACHT PF05729.12 EGO27073.1 - 0.13 12.2 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 EGO27073.1 - 0.14 11.9 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO27073.1 - 0.16 12.4 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.16 EGO27074.1 - 6.7e-15 54.9 24.2 6.7e-15 54.9 24.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EGO27074.1 - 1.8e-11 44.0 3.1 1.8e-11 44.0 3.1 1.7 2 0 0 2 2 2 1 Nodulin-like Tcf25 PF04910.14 EGO27075.1 - 1.4e-103 346.7 0.1 1.8e-103 346.3 0.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 EGO27075.1 - 0.0064 16.8 0.5 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat PutA_N PF18083.1 EGO27075.1 - 0.041 13.9 0.3 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Proline utilization A N-terminal domain TMEM214 PF10151.9 EGO27075.1 - 0.36 9.2 9.8 0.51 8.7 9.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator CENP-B_dimeris PF09026.10 EGO27075.1 - 3.9 7.9 15.3 0.18 12.2 6.5 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain p450 PF00067.22 EGO27076.1 - 1.9e-70 237.9 0.0 1.4e-69 235.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF5311 PF17238.2 EGO27076.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5311) SLC3A2_N PF16028.5 EGO27076.1 - 0.084 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus p450 PF00067.22 EGO27077.1 - 1e-64 219.1 0.0 2.8e-64 217.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Dicty_REP PF05086.12 EGO27078.1 - 0.00013 20.1 2.6 0.00015 19.9 2.6 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Paf1 PF03985.13 EGO27078.1 - 0.021 13.8 13.9 0.026 13.6 13.9 1.1 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 EGO27078.1 - 0.26 10.7 8.7 0.3 10.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1682 PF07946.14 EGO27078.1 - 1.5 8.0 15.9 1.7 7.8 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDHD PF02862.17 EGO27078.1 - 1.7 8.7 4.9 2.3 8.3 4.9 1.2 1 0 0 1 1 1 0 DDHD domain NOA36 PF06524.12 EGO27078.1 - 1.9 7.7 11.4 2.6 7.3 11.4 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EGO27078.1 - 3.5 5.8 14.9 3.9 5.7 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Retrotran_gag_2 PF14223.6 EGO27079.1 - 1.6e-07 31.0 0.3 2.5e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Homeodomain PF00046.29 EGO27080.1 - 0.032 14.1 0.3 0.052 13.4 0.3 1.4 1 0 0 1 1 1 0 Homeodomain DUF4407 PF14362.6 EGO27080.1 - 0.047 13.0 1.6 0.049 13.0 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 EGO27080.1 - 0.34 10.4 4.4 0.39 10.3 4.4 1.1 1 0 0 1 1 1 0 fzo-like conserved region Pkinase_fungal PF17667.1 EGO27081.1 - 0.00079 18.3 0.0 0.0009 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase IMPDH PF00478.25 EGO27083.1 - 2.5e-105 352.3 1.6 4.3e-70 236.4 0.0 2.7 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGO27083.1 - 1.5e-12 47.7 0.2 5.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EGO27083.1 - 0.0047 16.0 4.5 0.27 10.2 0.9 2.8 2 1 1 3 3 3 2 FMN-dependent dehydrogenase NMO PF03060.15 EGO27083.1 - 0.039 13.3 8.1 0.3 10.4 4.8 2.9 2 1 0 3 3 3 0 Nitronate monooxygenase HK PF02110.15 EGO27083.1 - 0.053 12.9 3.5 0.22 10.9 0.1 2.3 2 1 0 2 2 2 0 Hydroxyethylthiazole kinase family PEP_hydrolase PF09370.10 EGO27083.1 - 0.055 12.7 0.3 2.8 7.1 0.1 2.5 2 1 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Aldolase PF01081.19 EGO27083.1 - 0.082 12.3 0.8 0.34 10.3 0.6 2.2 2 1 0 2 2 2 0 KDPG and KHG aldolase F-box-like PF12937.7 EGO27084.1 - 2.4e-06 27.3 0.4 5.8e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO27084.1 - 0.00067 19.5 0.2 0.0018 18.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain Bactofilin PF04519.13 EGO27087.1 - 0.073 13.4 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Polymer-forming cytoskeletal ANAPC4_WD40 PF12894.7 EGO27092.1 - 0.045 14.1 0.0 21 5.5 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2 PF00096.26 EGO27094.1 - 3.5e-13 49.2 10.2 2.1e-06 27.9 4.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO27094.1 - 2.2e-11 43.6 8.6 2.8e-05 24.6 3.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO27094.1 - 2.5e-06 27.6 6.8 0.00026 21.3 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 EGO27094.1 - 1.5e-05 24.7 11.8 0.00078 19.3 2.4 2.6 2 1 0 2 2 2 2 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 EGO27094.1 - 0.0001 22.1 3.0 0.019 14.8 1.9 2.2 2 1 0 2 2 2 2 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 EGO27094.1 - 0.00019 21.6 5.7 0.00063 20.0 1.1 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO27094.1 - 0.0027 18.0 1.4 0.0027 18.0 1.4 2.2 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EGO27094.1 - 0.0038 17.5 4.6 0.013 15.8 4.6 1.8 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 EGO27094.1 - 0.011 15.7 0.2 0.24 11.3 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 EGO27094.1 - 0.019 15.0 0.2 0.74 9.9 0.1 2.0 1 1 1 2 2 2 0 CpXC protein zf-C2H2_11 PF16622.5 EGO27094.1 - 0.021 14.6 1.0 1.8 8.4 0.7 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EGO27094.1 - 0.023 14.5 11.6 0.16 11.8 4.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF3268 PF11672.8 EGO27094.1 - 0.11 12.9 0.1 0.12 12.8 0.1 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2_aberr PF17017.5 EGO27094.1 - 0.13 12.4 0.3 2 8.5 0.0 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 EGO27094.1 - 0.25 11.4 5.0 0.3 11.1 0.8 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGO27094.1 - 0.44 11.2 3.0 3.3 8.4 0.2 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain FYDLN_acid PF09538.10 EGO27094.1 - 1.3 9.7 3.6 8.1 7.2 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PAN_2 PF08276.11 EGO27099.1 - 0.016 15.3 4.2 0.023 14.8 4.2 1.3 1 0 0 1 1 1 0 PAN-like domain DUF2244 PF10003.9 EGO27100.1 - 0.48 10.1 5.9 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) PNP_UDP_1 PF01048.20 EGO27101.1 - 4.4e-31 108.0 0.0 5.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Laminin_G_3 PF13385.6 EGO27103.1 - 6.2e-13 49.2 4.3 1.9e-09 37.9 0.1 2.9 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily IlvB_leader PF08049.11 EGO27103.1 - 5.1 7.1 5.3 0.97 9.4 0.9 2.0 2 0 0 2 2 2 0 IlvB leader peptide DUF4473 PF14747.6 EGO27104.1 - 0.023 15.2 0.1 0.047 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Phage_head_chap PF11113.8 EGO27104.1 - 0.064 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Head assembly gene product baeRF_family12 PF18856.1 EGO27104.1 - 0.14 12.7 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 gag-asp_proteas PF13975.6 EGO27106.1 - 6.4e-07 29.8 0.0 7.4e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO27106.1 - 9.2e-07 29.4 0.0 1.1e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO27106.1 - 1.8e-06 27.8 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EGO27107.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein FAS_meander PF17951.1 EGO27109.1 - 0.08 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain zf-CCHC PF00098.23 EGO27109.1 - 0.11 12.7 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle PRKCSH-like PF12999.7 EGO27110.1 - 2.2e-49 167.6 0.5 6.2e-49 166.2 0.5 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGO27110.1 - 1e-23 83.7 0.0 2.2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EGO27110.1 - 2.5e-10 41.2 1.3 5e-10 40.3 0.4 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ribosomal_S25 PF03297.15 EGO27111.1 - 7.7e-39 132.0 0.3 8.4e-39 131.8 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 EGO27111.1 - 0.0022 17.5 0.2 0.0038 16.8 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EGO27111.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 MarR family MerR PF00376.23 EGO27111.1 - 0.046 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 MerR family regulatory protein GntR PF00392.21 EGO27111.1 - 0.1 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family FGGY_C PF02782.16 EGO27112.1 - 1.1e-48 165.7 0.0 1.8e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGO27112.1 - 4.2e-18 65.8 0.4 2.7e-17 63.2 0.4 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EGO27112.1 - 0.0066 16.0 0.2 0.21 11.1 0.1 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Ribosomal_L2_C PF03947.18 EGO27113.1 - 1.4e-45 154.5 3.3 1.4e-45 154.5 3.3 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGO27113.1 - 1.2e-14 54.0 0.1 3.1e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MotY_N PF18393.1 EGO27114.1 - 1.7 8.8 15.6 0.89 9.7 6.3 2.1 2 0 0 2 2 2 0 MotY N-terminal domain Spt20 PF12090.8 EGO27114.1 - 2.5 7.6 36.8 1.1 8.8 20.1 2.2 2 0 0 2 2 2 0 Spt20 family SH3_1 PF00018.28 EGO27115.1 - 5.9e-12 45.0 0.1 9.4e-12 44.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO27115.1 - 6.4e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO27115.1 - 3.7e-10 39.3 0.0 6.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GH43_C PF16369.5 EGO27115.1 - 0.071 13.7 0.5 0.11 13.1 0.5 1.2 1 0 0 1 1 1 0 C-terminal lipocalin-like domain Dscam_C PF12355.8 EGO27115.1 - 9.5 7.2 21.7 0.05 14.6 6.5 2.4 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal UAA PF08449.11 EGO27116.1 - 9.4e-26 90.7 2.0 9.9e-26 90.6 2.0 1.0 1 0 0 1 1 1 1 UAA transporter family MIF4G_like_2 PF09090.11 EGO27117.1 - 3e-74 249.8 0.0 4.1e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 EGO27117.1 - 3.5e-65 219.4 0.0 1.1e-64 217.8 0.0 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 EGO27117.1 - 0.081 12.6 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 MIF4G domain CNOT11 PF10155.9 EGO27117.1 - 0.11 12.6 0.4 0.65 10.2 0.0 2.4 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 Nucleoside_tran PF01733.18 EGO27119.1 - 0.19 11.1 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter PPR_1 PF12854.7 EGO27120.1 - 0.02 14.6 0.3 0.84 9.4 0.2 2.6 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 EGO27120.1 - 0.022 14.9 0.0 5.1 7.4 0.0 3.7 4 0 0 4 4 4 0 PPR repeat family PPR PF01535.20 EGO27120.1 - 0.26 11.6 1.3 4.1 7.9 0.0 3.5 4 0 0 4 4 4 0 PPR repeat Mito_carr PF00153.27 EGO27121.1 - 3.5e-62 206.4 3.1 2.5e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_capsid PF06112.11 EGO27123.1 - 6.7 6.7 10.4 11 6.0 10.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Acyl-CoA_dh_1 PF00441.24 EGO27124.1 - 8.5e-31 107.2 0.6 1.4e-30 106.5 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO27124.1 - 4.8e-18 65.1 0.3 1e-17 64.1 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EGO27124.1 - 5.4e-16 58.5 0.0 1.5e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGO27124.1 - 3.8e-15 56.5 0.0 1.3e-14 54.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO27124.1 - 7.5e-06 26.3 0.2 1.3e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.23 EGO27125.1 - 2.2e-54 184.5 0.1 6.2e-53 179.7 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO27125.1 - 5.5e-15 55.7 0.0 1.5e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EGO27125.1 - 1.2e-05 25.0 3.8 1.2e-05 25.0 3.8 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGO27125.1 - 1.3e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EGO27125.1 - 3.1e-05 24.2 5.1 3.1e-05 24.2 5.1 2.7 2 1 0 2 2 2 1 Ring finger domain DEAD PF00270.29 EGO27125.1 - 3.9e-05 23.5 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 EGO27125.1 - 4.7e-05 23.1 3.8 4.7e-05 23.1 3.8 2.8 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO27125.1 - 5.3e-05 23.4 2.1 0.00014 22.1 2.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EGO27125.1 - 0.00029 20.6 2.7 0.0008 19.2 2.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 EGO27125.1 - 0.00077 19.3 3.6 0.00077 19.3 3.6 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO27125.1 - 0.0043 17.1 0.3 0.0043 17.1 0.3 2.9 2 2 0 2 2 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGO27125.1 - 0.0088 16.1 0.7 0.025 14.6 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGO27125.1 - 0.0091 15.8 4.5 0.0091 15.8 4.5 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGO27125.1 - 0.12 12.2 1.3 0.31 10.9 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ERCC3_RAD25_C PF16203.5 EGO27125.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase F_bP_aldolase PF01116.20 EGO27126.1 - 2.3e-91 306.1 0.0 2.6e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.11 EGO27126.1 - 0.0054 16.8 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Torsin CPSase_L_D2 PF02786.17 EGO27126.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain WW PF00397.26 EGO27128.1 - 1.5e-07 31.3 7.4 3.1e-07 30.4 7.4 1.5 1 0 0 1 1 1 1 WW domain DUF515 PF04415.12 EGO27129.1 - 1.8 6.9 5.6 2 6.7 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HMG_box PF00505.19 EGO27130.1 - 2.7e-18 66.1 2.4 3.2e-18 65.9 2.4 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO27130.1 - 3.6e-11 43.5 2.2 4.4e-11 43.2 2.2 1.1 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EGO27130.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain Protamine_like PF06382.11 EGO27130.1 - 0.023 14.9 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Protamine and protamine like YABBY PF04690.13 EGO27130.1 - 0.077 13.6 0.6 0.91 10.1 0.0 2.0 1 1 1 2 2 2 0 YABBY protein Med26 PF08711.11 EGO27131.1 - 2.2e-09 37.2 0.3 4.6e-09 36.2 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH_4 PF18044.1 EGO27131.1 - 7.7e-07 28.8 2.5 1.2e-06 28.1 2.5 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGO27131.1 - 8.8e-06 25.5 4.1 1.4e-05 24.8 4.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO27131.1 - 1.8e-05 24.6 4.9 3.1e-05 23.9 4.9 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EGO27131.1 - 0.0021 18.7 0.3 0.0058 17.3 0.3 1.8 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 EGO27131.1 - 0.32 11.5 4.0 0.55 10.8 4.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger S4 PF01479.25 EGO27132.1 - 7.3e-12 44.8 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EGO27132.1 - 8.4e-11 42.6 0.2 1.2e-10 42.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Herpes_LAMP2 PF06126.11 EGO27132.1 - 0.17 10.5 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Kinesin PF00225.23 EGO27133.1 - 4e-97 325.1 0.0 7.1e-97 324.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EGO27133.1 - 4.8e-43 147.5 0.0 1.5e-42 145.9 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EGO27133.1 - 3.5e-36 125.0 6.2 1.5e-27 96.9 2.6 2.8 1 1 1 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 EGO27133.1 - 2e-12 47.3 0.1 5.9e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 EGO27133.1 - 2.8e-09 37.4 0.0 2.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 PH domain FHA PF00498.26 EGO27133.1 - 9e-07 29.2 0.0 3.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 EGO27133.1 - 1.4e-06 28.6 0.3 1.4e-06 28.6 0.3 2.4 2 0 0 2 2 1 1 Kinesin protein 1B EAP30 PF04157.16 EGO27133.1 - 0.016 14.5 1.3 0.034 13.4 0.4 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family EPOP PF15223.6 EGO27133.1 - 0.32 10.3 4.6 0.54 9.6 4.6 1.3 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein PilJ PF13675.6 EGO27133.1 - 0.99 9.4 6.1 11 6.1 0.2 3.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term MutS_III PF05192.18 EGO27133.1 - 4.9 7.3 10.2 5.8 7.1 0.0 3.5 3 1 0 3 3 3 0 MutS domain III Arf PF00025.21 EGO27135.1 - 6.8e-70 234.1 0.6 7.7e-70 233.9 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGO27135.1 - 2.7e-14 53.1 0.9 2.6e-08 33.4 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGO27135.1 - 8e-11 42.2 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGO27135.1 - 2.4e-09 36.9 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO27135.1 - 5.5e-09 35.7 0.0 7.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGO27135.1 - 8.1e-09 35.3 0.0 9.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGO27135.1 - 1e-06 28.8 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO27135.1 - 0.011 15.2 0.1 0.16 11.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGO27135.1 - 0.033 13.9 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGO27135.1 - 0.097 12.3 0.1 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EGO27135.1 - 0.1 12.6 0.0 0.69 9.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Peptidase_M24 PF00557.24 EGO27136.1 - 2.5e-39 135.1 0.0 3.5e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGO27136.1 - 1.3e-38 131.4 0.0 2.4e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TetR_C_30 PF17939.1 EGO27136.1 - 0.041 14.1 0.1 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lipase_3 PF01764.25 EGO27137.1 - 1.6e-16 60.4 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGO27137.1 - 0.019 14.2 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO27137.1 - 0.043 14.4 0.3 0.086 13.4 0.3 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Spt4 PF06093.13 EGO27138.1 - 8.5e-29 99.5 0.1 1e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Med13_N PF11597.8 EGO27140.1 - 5e-58 196.9 3.7 9.7e-58 196.0 3.7 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 EGO27140.1 - 1.1e-56 192.5 8.1 1.1e-56 192.5 8.1 3.4 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 EGO27140.1 - 0.00058 19.7 5.2 0.087 12.6 0.0 3.0 2 1 1 3 3 3 2 MID domain of medPIWI MerR PF00376.23 EGO27140.1 - 0.13 12.1 0.0 0.42 10.4 0.0 1.9 1 0 0 1 1 1 0 MerR family regulatory protein DUF2433 PF10360.9 EGO27141.1 - 2.8e-47 159.9 0.0 6.6e-47 158.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 EGO27141.1 - 0.00026 20.8 0.1 0.00054 19.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EGO27141.1 - 0.043 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO27141.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SWI-SNF_Ssr4 PF08549.10 EGO27141.1 - 0.57 8.8 12.9 0.92 8.1 12.9 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Hamartin PF04388.12 EGO27141.1 - 1.2 7.7 17.2 1.8 7.1 17.2 1.3 1 0 0 1 1 1 0 Hamartin protein LAP1C PF05609.12 EGO27141.1 - 1.4 8.0 9.5 2 7.4 9.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 EGO27141.1 - 3.2 6.2 9.6 4.3 5.8 9.6 1.1 1 0 0 1 1 1 0 Macoilin family CDC27 PF09507.10 EGO27141.1 - 8.5 5.7 30.5 18 4.6 30.5 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 EGO27141.1 - 8.5 5.0 8.2 11 4.6 8.2 1.2 1 0 0 1 1 1 0 Presenilin Acyl-CoA_dh_1 PF00441.24 EGO27142.1 - 7.6e-43 146.3 2.6 1.1e-42 145.8 2.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO27142.1 - 4e-25 88.7 0.2 2.6e-24 86.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGO27142.1 - 1.1e-22 80.0 0.1 3.7e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO27142.1 - 3.2e-21 76.0 0.3 5.3e-21 75.3 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mito_carr PF00153.27 EGO27143.1 - 5.6e-15 55.0 0.1 5.9e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Serine_protease PF18405.1 EGO27143.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.3 1 1 0 1 1 1 0 Gammaproteobacterial serine protease RhoGEF PF00621.20 EGO27144.1 - 4.9e-15 56.2 0.0 1.3e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain Orthopox_A5L PF06193.11 EGO27145.1 - 0.042 13.3 1.7 0.053 13.0 1.7 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like NosL PF05573.12 EGO27146.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 NosL RNA_pol_Rpb1_1 PF04997.12 EGO27147.1 - 1.1e-86 291.1 0.0 1.6e-86 290.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGO27147.1 - 7.5e-83 278.0 0.3 1.1e-82 277.5 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGO27147.1 - 9.5e-73 243.9 0.0 1.9e-72 242.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGO27147.1 - 1.5e-39 135.4 0.0 5.5e-38 130.4 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGO27147.1 - 1.1e-32 112.1 0.0 3e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Proteasome PF00227.26 EGO27148.1 - 9.6e-47 158.9 0.1 3.8e-46 157.0 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO27148.1 - 9.9e-15 53.9 0.3 2.1e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GDI PF00996.18 EGO27149.1 - 4.4e-15 55.1 0.1 2.2e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 GDP dissociation inhibitor DUF5315 PF17242.2 EGO27149.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Ric8 PF10165.9 EGO27150.1 - 8.3e-129 430.6 0.0 1e-128 430.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.9 EGO27151.1 - 7e-21 74.4 0.2 8.3e-21 74.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 EGO27151.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 PIN domain KIAA1430 PF13879.6 EGO27151.1 - 0.043 14.6 0.2 0.063 14.0 0.2 1.3 1 0 0 1 1 1 0 KIAA1430 homologue S6OS1 PF15676.5 EGO27151.1 - 0.09 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family PMI_typeI PF01238.21 EGO27152.1 - 2.6e-117 392.2 0.0 3.2e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EGO27152.1 - 9.5e-06 25.2 0.0 0.0067 16.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EGO27152.1 - 2.6e-05 24.1 0.0 0.016 15.1 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_3 PF05899.12 EGO27152.1 - 0.0071 16.0 0.1 0.027 14.2 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 EGO27152.1 - 0.012 15.4 0.0 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Cupin Lipase_3 PF01764.25 EGO27153.1 - 3.9e-23 81.9 0.0 5.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO27153.1 - 0.0068 17.0 1.1 0.0094 16.6 0.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO27153.1 - 0.015 14.5 0.2 0.024 13.9 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 STE3 PF02076.15 EGO27154.1 - 3.1e-55 187.4 7.2 3.9e-55 187.1 7.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4381 PF14316.6 EGO27154.1 - 0.25 11.6 0.7 0.59 10.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Lipase_3 PF01764.25 EGO27155.1 - 6.1e-21 74.8 0.0 8.9e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO27155.1 - 0.021 15.5 0.1 0.027 15.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO27155.1 - 0.022 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPP_enzyme_C PF02775.21 EGO27155.1 - 0.14 11.9 1.1 0.59 9.9 0.1 2.4 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short_C2 PF13561.6 EGO27156.1 - 2.1e-50 171.5 0.4 2.7e-50 171.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO27156.1 - 1.4e-42 145.4 0.2 1.9e-42 144.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO27156.1 - 2e-07 31.1 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO27156.1 - 0.0042 16.5 0.0 0.0081 15.6 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 EGO27156.1 - 0.011 15.1 0.1 0.05 13.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EGO27156.1 - 0.13 11.7 0.1 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family EF-hand_1 PF00036.32 EGO27159.1 - 4.9e-26 88.3 9.6 5.8e-06 25.5 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO27159.1 - 3.3e-24 85.1 4.6 4.8e-14 52.6 1.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO27159.1 - 9e-22 75.1 5.5 4.7e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGO27159.1 - 3.3e-16 57.9 12.3 2.8e-05 23.4 0.4 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGO27159.1 - 1.8e-12 46.9 11.8 0.00033 20.4 0.5 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGO27159.1 - 8.7e-06 26.0 0.0 0.041 14.2 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGO27159.1 - 3.7e-05 23.6 5.2 0.0083 16.1 0.7 3.6 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand MnmE_helical PF12631.7 EGO27160.1 - 7.2e-43 147.2 0.0 9.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EGO27160.1 - 3.9e-35 120.7 0.0 8.4e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EGO27160.1 - 8.8e-17 61.2 0.0 2.5e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO27160.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO27160.1 - 0.00046 20.3 0.0 0.0016 18.5 0.0 2.0 1 0 0 1 1 1 1 Dynamin family AAA_18 PF13238.6 EGO27160.1 - 0.016 15.7 0.0 0.057 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO27160.1 - 0.02 14.8 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 EGO27160.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EGO27162.1 - 8.1e-17 61.3 16.1 2.6e-06 28.1 2.1 6.2 5 1 1 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 EGO27162.1 - 1.8e-07 31.3 1.0 1.7e-05 24.8 0.1 3.4 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGO27162.1 - 0.00044 20.5 0.2 15 6.0 0.0 4.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Tti2 PF10521.9 EGO27163.1 - 1.6e-55 188.7 0.0 2.1e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Tti2 family Plavaka PF18759.1 EGO27164.1 - 0.00056 19.2 0.0 0.00056 19.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 EGO27165.1 - 2.8e-40 138.5 0.1 4.3e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 EGO27166.1 - 4.8e-08 33.5 16.1 0.085 13.8 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27166.1 - 0.11 12.8 1.4 4.4 7.7 0.2 3.6 3 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 EGO27168.1 - 6.9e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO27168.1 - 5.5e-06 26.4 11.1 9.8e-06 25.6 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT PF03062.19 EGO27169.1 - 3.6e-44 151.5 6.2 8.6e-44 150.3 6.2 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family HXXEE PF13787.6 EGO27169.1 - 3.8 8.3 16.5 0.21 12.4 3.3 4.0 4 1 0 4 4 4 0 Protein of unknown function with HXXEE motif Bestrophin PF01062.21 EGO27170.1 - 1.7e-35 122.9 0.0 1.3e-20 74.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Ribosomal_L18 PF17135.4 EGO27171.1 - 4.4e-90 300.1 2.0 4.9e-90 300.0 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGO27171.1 - 0.00054 20.6 0.9 0.00081 20.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 EGO27172.1 - 1.6e-16 59.9 0.0 2.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO27172.1 - 0.00033 20.2 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.9 EGO27172.1 - 7.3 5.6 23.9 3.9 6.5 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TAF1_subA PF14929.6 EGO27173.1 - 0.014 14.8 0.0 0.015 14.7 0.0 1.0 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A AMNp_N PF10423.9 EGO27174.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus zf-RVT PF13966.6 EGO27178.1 - 0.12 13.1 0.1 0.38 11.5 0.0 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Acyl-ACP_TE PF01643.17 EGO27178.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase ADH_N PF08240.12 EGO27183.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.8 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AF-4 PF05110.13 EGO27183.1 - 1.7 6.6 6.5 3 5.8 6.5 1.3 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Retrotrans_gag PF03732.17 EGO27184.1 - 5.5e-07 29.8 2.0 5.5e-07 29.8 2.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO27184.1 - 0.0042 16.9 0.1 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) M64_N PF16217.5 EGO27184.1 - 0.0087 15.6 0.3 0.021 14.4 0.3 1.7 1 0 0 1 1 1 1 Peptidase M64 N-terminus JmjC PF02373.22 EGO27185.1 - 6.5e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGO27185.1 - 0.0015 18.3 0.8 0.032 13.9 0.1 2.8 2 1 0 2 2 2 1 Cupin-like domain C1_1 PF00130.22 EGO27185.1 - 0.0055 16.6 3.3 0.015 15.2 3.3 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EGO27185.1 - 0.013 15.5 1.5 0.036 14.2 1.5 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger FYVE PF01363.21 EGO27185.1 - 1.1 9.4 13.0 0.064 13.4 6.9 2.1 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_2 PF14445.6 EGO27185.1 - 1.2 9.4 12.1 0.21 11.8 3.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Response_reg PF00072.24 EGO27186.1 - 3.1e-23 82.1 0.0 9.8e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DUF3546 PF12066.8 EGO27187.1 - 1.1e-15 57.8 1.4 4.5e-15 55.8 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EGO27187.1 - 1.5e-15 58.1 1.6 1.5e-15 58.1 1.6 4.0 4 1 1 5 5 5 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EGO27187.1 - 0.00019 21.1 3.0 0.00039 20.2 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 EGO27187.1 - 0.015 15.6 3.2 0.51 10.7 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGO27187.1 - 0.21 12.1 4.5 0.15 12.5 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1871 PF08958.10 EGO27187.1 - 0.24 11.7 0.8 3.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) DUF1682 PF07946.14 EGO27187.1 - 1.3 8.1 7.1 2.2 7.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RRM_1 PF00076.22 EGO27188.1 - 0.011 15.6 0.0 0.74 9.7 0.0 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NCBP3 PF10309.9 EGO27189.1 - 3.3e-10 39.6 0.0 6.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 EGO27189.1 - 0.0046 17.5 3.1 0.0046 17.5 3.1 2.8 3 1 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 DUF3110 PF11360.8 EGO27189.1 - 0.097 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) KH_8 PF17903.1 EGO27190.1 - 2.3e-32 110.9 0.1 2.3e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EGO27190.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EGO27190.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 KH domain PNTB_4TM PF12769.7 EGO27191.1 - 0.039 14.4 2.5 0.12 12.8 2.5 1.9 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Peptidase_S10 PF00450.22 EGO27192.1 - 2.5e-107 359.9 0.1 3.7e-107 359.3 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.18 EGO27193.1 - 2.2e-84 282.5 0.0 4.2e-84 281.6 0.0 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGO27193.1 - 1.3e-20 73.5 1.1 5e-20 71.7 1.1 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Nucleo_P87 PF07267.11 EGO27193.1 - 3 6.6 11.4 5.1 5.8 11.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Med5 PF08689.10 EGO27193.1 - 3.9 5.2 7.4 5.7 4.6 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 adh_short PF00106.25 EGO27194.1 - 5.6e-10 39.0 0.1 8.1e-05 22.2 0.0 3.3 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO27194.1 - 0.021 14.4 0.0 7.7 6.0 0.0 2.7 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ATP_bind_3 PF01171.20 EGO27195.1 - 3.8e-18 65.9 0.0 6.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EGO27195.1 - 1.1e-15 56.8 4.3 1.1e-15 56.8 4.3 4.1 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 EGO27195.1 - 0.018 14.6 1.7 0.018 14.6 1.7 3.0 4 0 0 4 4 4 0 RecR protein DNA_pol_B_palm PF14792.6 EGO27195.1 - 0.025 14.8 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm CTU2 PF10288.9 EGO27195.1 - 0.033 14.4 3.4 0.27 11.5 0.1 3.1 2 1 1 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 tRNA_Me_trans PF03054.16 EGO27195.1 - 0.046 12.5 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase PUF PF00806.19 EGO27196.1 - 2.9e-23 80.2 0.0 0.00012 21.6 0.0 8.4 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat LidA_Long_CC PF18641.1 EGO27196.1 - 0.029 14.4 0.1 0.029 14.4 0.1 1.8 2 0 0 2 2 2 0 LidA long coiled-coil domain Lipoprotein_10 PF03202.13 EGO27196.1 - 0.045 14.2 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Abhydrolase_6 PF12697.7 EGO27197.1 - 3.1e-15 57.4 2.2 8.9e-14 52.6 2.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO27197.1 - 9.2e-07 28.8 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO27197.1 - 0.0025 17.1 0.1 0.025 13.9 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Glyco_hydro_79C PF16862.5 EGO27198.1 - 4.9e-18 65.9 3.2 5.1e-18 65.9 1.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain DAGK_cat PF00781.24 EGO27198.1 - 0.021 14.4 0.3 0.044 13.4 0.3 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Bystin PF05291.11 EGO27199.1 - 1.9e-99 332.6 0.0 4.8e-65 219.7 0.0 2.1 1 1 1 2 2 2 2 Bystin GCIP PF13324.6 EGO27199.1 - 2.1 7.9 6.2 4.4 6.8 6.2 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 EGO27199.1 - 4.3 5.4 16.6 7.3 4.7 16.6 1.3 1 0 0 1 1 1 0 Nop14-like family GDP_Man_Dehyd PF16363.5 EGO27200.1 - 3.5e-62 210.7 0.0 4.6e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO27200.1 - 3.9e-47 160.8 0.0 5.2e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO27200.1 - 5.4e-10 38.7 0.0 8.5e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO27200.1 - 4.4e-07 29.3 0.1 0.0034 16.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGO27200.1 - 1e-06 28.1 0.3 0.0033 16.6 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGO27200.1 - 2.1e-06 27.1 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain MurB_C PF02873.16 EGO27200.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF1408 PF07193.11 EGO27203.1 - 0.036 14.2 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) RGS PF00615.19 EGO27204.1 - 2.7e-40 137.3 0.1 9e-40 135.6 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 EGO27204.1 - 2e-13 50.2 0.0 7.2e-06 26.0 0.0 3.6 3 1 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.6 EGO27204.1 - 0.021 14.8 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix Cyt-b5 PF00173.28 EGO27205.1 - 1.5e-09 37.8 0.3 2.7e-09 37.0 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nup160 PF11715.8 EGO27207.1 - 2.2e-39 135.5 0.0 3.8e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO27207.1 - 0.037 12.8 0.0 0.066 11.9 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Fungal_trans PF04082.18 EGO27208.1 - 3.2e-16 59.2 0.4 1.4e-15 57.1 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO27208.1 - 3.9e-05 23.7 8.7 6.6e-05 23.0 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STI1 PF17830.1 EGO27209.1 - 1.6e-18 66.4 5.4 2.9e-18 65.5 5.4 1.4 1 0 0 1 1 1 1 STI1 domain TPR_2 PF07719.17 EGO27209.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO27209.1 - 0.009 15.8 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Pterin_4a PF01329.19 EGO27209.1 - 0.015 15.5 0.2 0.021 15.0 0.2 1.2 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase XPC-binding PF09280.11 EGO27209.1 - 0.018 14.8 1.5 0.041 13.6 1.5 1.7 1 0 0 1 1 1 0 XPC-binding domain DUF627 PF04781.12 EGO27209.1 - 0.022 14.7 0.7 0.041 13.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_8 PF13181.6 EGO27209.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat COP23 PF14218.6 EGO27209.1 - 0.051 13.3 0.4 0.27 11.0 0.4 2.1 1 1 0 1 1 1 0 Circadian oscillating protein COP23 TPR_19 PF14559.6 EGO27209.1 - 0.1 13.1 0.3 1.2 9.7 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Bud13 PF09736.9 EGO27209.1 - 0.39 11.1 5.4 0.5 10.8 5.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex TPR_1 PF00515.28 EGO27210.1 - 1.4e-08 34.1 1.1 1.4e-08 34.1 1.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO27210.1 - 5.6e-08 32.3 0.6 5.6e-08 32.3 0.6 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO27210.1 - 3.8e-06 26.5 1.2 6.9e-06 25.6 0.2 1.9 1 1 1 2 2 2 1 TPR repeat TPR_14 PF13428.6 EGO27210.1 - 0.00036 21.1 0.1 0.00064 20.3 0.1 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO27210.1 - 0.00049 20.7 0.9 0.0011 19.6 0.8 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO27210.1 - 0.00049 20.5 0.7 0.00089 19.7 0.7 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO27210.1 - 0.00089 19.3 2.9 0.001 19.1 0.4 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO27210.1 - 0.003 17.8 0.2 0.0091 16.3 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGO27210.1 - 0.0056 16.7 0.5 0.0056 16.7 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGO27210.1 - 0.006 17.0 0.3 0.0065 16.9 0.3 1.1 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation TPR_7 PF13176.6 EGO27210.1 - 0.021 14.8 0.0 0.05 13.7 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 EGO27210.1 - 0.022 14.8 0.6 0.03 14.4 0.6 1.4 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EGO27210.1 - 0.04 14.3 1.6 0.32 11.5 0.1 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 EGO27210.1 - 0.072 13.8 0.1 0.072 13.8 0.1 1.7 2 0 0 2 2 2 0 Sel1 repeat TPR_6 PF13174.6 EGO27210.1 - 0.087 13.5 0.1 0.087 13.5 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EGO27211.1 - 8.1e-42 143.4 0.0 9.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PE_PPE_C PF12484.8 EGO27211.1 - 0.085 13.8 0.2 0.21 12.5 0.1 1.7 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal B12D PF06522.11 EGO27212.1 - 1.2e-17 63.4 0.1 1.7e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ATG16 PF08614.11 EGO27213.1 - 0.31 11.2 16.9 1.1 9.5 14.3 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DNA_ligase_aden PF01653.18 EGO27213.1 - 0.39 9.8 3.0 0.64 9.0 0.0 2.4 2 1 1 3 3 3 0 NAD-dependent DNA ligase adenylation domain Isochorismatase PF00857.20 EGO27214.1 - 4e-30 105.3 0.0 5.7e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF1748 PF08520.10 EGO27215.1 - 1e-23 83.0 0.0 1.1e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DAD PF02109.16 EGO27216.1 - 9.4e-49 164.3 1.1 1.1e-48 164.1 1.1 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.18 EGO27217.1 - 5.7e-12 45.7 0.0 5.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Adap_comp_sub PF00928.21 EGO27218.1 - 8.6e-49 166.3 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO27218.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hexokinase_2 PF03727.16 EGO27219.1 - 4.3e-75 252.2 0.0 6.3e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGO27219.1 - 8.5e-69 231.4 0.0 1.3e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 EGO27219.1 - 0.037 14.1 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Sina PF03145.16 EGO27220.1 - 0.071 13.0 1.6 2.4 8.0 0.4 2.2 1 1 1 2 2 2 0 Seven in absentia protein family IL11 PF07400.11 EGO27220.1 - 0.073 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Interleukin 11 zf-C2HC PF01530.18 EGO27220.1 - 1.1 9.5 4.0 6.1 7.1 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2HC type COX7C PF02935.16 EGO27221.1 - 0.08 13.2 0.0 0.092 13.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DUF3445 PF11927.8 EGO27222.1 - 1.3e-69 234.2 0.0 1.7e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Aft1_HRA PF11786.8 EGO27223.1 - 1.6e-25 89.2 10.4 1.6e-25 89.2 10.4 3.5 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 EGO27223.1 - 1.7e-10 40.9 9.6 3e-10 40.0 9.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO27223.1 - 6.5e-06 26.1 9.0 1.4e-05 25.0 9.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 EGO27223.1 - 4.5e-05 23.8 2.7 4.5e-05 23.8 2.7 3.1 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Spt5_N PF11942.8 EGO27223.1 - 0.21 12.6 11.9 0.15 13.1 9.7 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ASD2 PF08687.11 EGO27223.1 - 0.53 9.8 7.7 0.052 13.1 0.9 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Aft1_HRR PF11787.8 EGO27223.1 - 0.63 11.3 19.1 0.064 14.4 4.2 4.3 3 1 0 3 3 3 0 Aft1 HRR domain CDC45 PF02724.14 EGO27223.1 - 1.3 7.2 8.6 2.4 6.3 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein bZIP_Maf PF03131.17 EGO27223.1 - 5.4 7.6 12.1 0.54 10.8 7.0 1.9 2 1 0 2 2 2 0 bZIP Maf transcription factor Nop53 PF07767.11 EGO27223.1 - 7.9 5.8 20.5 15 4.8 18.7 2.0 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) Mt_ATP-synt_D PF05873.12 EGO27226.1 - 1.2e-14 54.4 1.0 1.5e-14 54.1 1.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) XhlA PF10779.9 EGO27226.1 - 0.024 14.8 0.8 0.065 13.4 0.8 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF948 PF06103.11 EGO27226.1 - 0.24 11.7 4.1 0.97 9.7 3.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2838 PF10998.8 EGO27227.1 - 5.8e-43 145.6 8.5 5.8e-43 145.6 8.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) A_deamin PF02137.18 EGO27228.1 - 3.5e-56 191.0 0.0 4.4e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Pectate_lyase_3 PF12708.7 EGO27229.1 - 3.9e-85 285.1 16.5 1.2e-75 254.0 9.8 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO27229.1 - 2.7e-05 23.7 0.2 0.031 14.0 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase FAD_binding_4 PF01565.23 EGO27232.1 - 2.7e-30 104.9 3.2 2.7e-30 104.9 3.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGO27232.1 - 1.8e-06 28.0 0.0 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Mig-14 PF07395.11 EGO27232.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Mig-14 Methyltransf_16 PF10294.9 EGO27234.1 - 7.6e-46 156.0 0.0 9.5e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase BolA PF01722.18 EGO27235.1 - 6.1e-13 48.8 0.0 1.8e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein COX15-CtaA PF02628.15 EGO27236.1 - 6.7e-107 357.3 8.6 8.3e-107 357.0 8.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 EGO27236.1 - 0.041 14.0 1.3 3.7 7.6 0.2 3.2 3 0 0 3 3 3 0 Fumarate reductase subunit C Proteasome PF00227.26 EGO27237.1 - 5.8e-56 189.0 0.0 7.1e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO27237.1 - 6.2e-13 48.2 1.7 1.2e-12 47.3 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SH3BP5 PF05276.14 EGO27240.1 - 0.0002 21.3 17.3 0.00024 21.0 17.3 1.1 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Trypan_glycop PF00913.19 EGO27240.1 - 0.053 12.8 14.6 0.065 12.5 14.6 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF4139 PF13598.6 EGO27240.1 - 0.13 11.9 4.6 0.14 11.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) SOBP PF15279.6 EGO27240.1 - 0.78 10.3 8.6 0.87 10.1 8.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PDE4_UCR PF18100.1 EGO27240.1 - 1 10.0 8.8 1.6 9.4 8.8 1.3 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) APG6_N PF17675.1 EGO27240.1 - 1.7 9.2 21.0 2.6 8.6 21.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Mit_KHE1 PF10173.9 EGO27240.1 - 7.2 6.6 9.1 9.1 6.3 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Pal1 PF08316.11 EGO27240.1 - 9.2 7.0 10.9 1.3 9.8 2.0 2.1 1 1 1 2 2 2 0 Pal1 cell morphology protein HNH_2 PF13391.6 EGO27241.1 - 7.7e-07 29.2 0.1 2.1e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease MS_channel PF00924.18 EGO27242.1 - 3.3e-21 75.8 2.2 6e-21 74.9 2.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EGO27242.1 - 1.2e-05 24.5 0.3 0.00036 19.9 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGO27242.1 - 2.1e-05 24.1 0.8 0.00068 19.4 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGO27242.1 - 0.0028 17.1 0.2 0.013 15.0 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGO27242.1 - 0.036 14.5 0.2 0.17 12.4 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair DUF4598 PF15370.6 EGO27243.1 - 0.035 14.6 0.1 0.062 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) GTP_EFTU PF00009.27 EGO27244.1 - 2.7e-33 115.2 0.0 3.6e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO27244.1 - 2e-14 53.9 0.0 8.6e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGO27244.1 - 0.0028 17.7 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGO27244.1 - 0.009 16.4 0.2 0.032 14.6 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SSB PF00436.25 EGO27245.1 - 2.7e-16 59.5 0.0 3.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Haem_degrading PF03928.14 EGO27246.1 - 9.5e-12 45.0 0.0 2.4e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Haem-degrading Pex2_Pex12 PF04757.14 EGO27247.1 - 5.3e-46 157.0 3.9 6.2e-46 156.8 3.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGO27247.1 - 8.8e-05 22.3 1.2 0.00015 21.6 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO27247.1 - 0.00021 21.0 2.0 0.00037 20.3 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO27247.1 - 0.0015 18.8 1.3 0.0028 17.9 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGO27247.1 - 0.019 14.9 0.7 0.032 14.1 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO27247.1 - 0.039 14.0 3.8 0.07 13.2 3.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO27247.1 - 0.11 12.7 2.6 0.2 11.9 2.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGO27247.1 - 0.24 11.3 2.3 6.6 6.7 3.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGO27247.1 - 2.9 7.7 4.9 15 5.5 5.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain NPDC1 PF06809.11 EGO27249.1 - 0.095 11.7 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) GDPD PF03009.17 EGO27250.1 - 5.4e-10 39.4 0.0 1.3e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.27 EGO27251.1 - 1.5e-24 87.1 0.0 2.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO27251.1 - 3.4e-10 40.2 0.4 2.6e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO27251.1 - 2.6e-05 23.7 0.0 0.24 10.8 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGO27251.1 - 9.1e-05 22.3 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 EGO27251.1 - 0.00063 18.5 0.0 0.22 10.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EGO27251.1 - 0.0048 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EGO27251.1 - 0.021 14.9 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 EGO27251.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO27251.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO27251.1 - 0.094 13.1 0.3 0.31 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Tap-RNA_bind PF09162.10 EGO27251.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Tap, RNA-binding AAA_24 PF13479.6 EGO27251.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO27251.1 - 0.14 12.5 0.0 9.2 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGO27251.1 - 0.23 10.6 0.2 0.74 8.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_88 PF07470.13 EGO27253.1 - 5e-22 78.4 0.4 6.6e-22 78.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 WIYLD PF10440.9 EGO27253.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Na_Ca_ex PF01699.24 EGO27254.1 - 9.2e-08 32.2 30.1 0.00087 19.3 12.7 3.0 2 2 0 2 2 2 2 Sodium/calcium exchanger protein Acyltransferase PF01553.21 EGO27255.1 - 1.6e-16 60.2 0.0 1.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase MRC1 PF09444.10 EGO27257.1 - 1.1e-28 100.6 29.4 1.1e-28 100.6 29.4 6.7 6 0 0 6 6 6 1 MRC1-like domain p450 PF00067.22 EGO27258.1 - 4.1e-74 250.0 0.0 5.5e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 EGO27259.1 - 5.2e-45 153.8 0.1 6.4e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO27259.1 - 1.9e-30 105.8 0.4 2.3e-30 105.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO27259.1 - 4.9e-10 39.6 0.0 1e-09 38.5 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF4236 PF14020.6 EGO27259.1 - 0.13 12.9 0.1 0.61 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) Ribosomal_L3 PF00297.22 EGO27260.1 - 7.2e-186 617.5 9.9 8.1e-186 617.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.6 EGO27261.1 - 3e-11 43.3 0.2 3.8e-05 23.8 0.0 5.2 4 1 2 6 6 6 3 PPR repeat family PPR PF01535.20 EGO27261.1 - 4.3e-10 39.1 0.3 0.00041 20.4 0.0 5.8 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.7 EGO27261.1 - 8.5e-08 31.8 2.3 4.8e-05 23.0 0.0 3.6 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 EGO27261.1 - 2.7e-07 30.5 0.0 0.018 15.1 0.0 3.9 3 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGO27261.1 - 0.15 11.4 0.1 1 8.7 0.0 2.3 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP Ras PF00071.22 EGO27262.1 - 4.3e-47 159.7 0.0 3.8e-43 146.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGO27262.1 - 1.3e-32 112.5 0.0 2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO27262.1 - 3.3e-11 43.0 0.0 5.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO27262.1 - 9e-07 29.0 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGO27262.1 - 0.0019 17.9 0.1 0.072 12.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EGO27262.1 - 0.0021 17.5 0.0 0.0042 16.5 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO27262.1 - 0.0021 17.5 0.0 0.007 15.8 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGO27262.1 - 0.005 17.1 0.1 0.013 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO27262.1 - 0.017 15.0 0.0 0.059 13.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGO27262.1 - 0.028 14.8 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGO27262.1 - 0.059 12.9 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EGO27262.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Dynamin family Septin PF00735.18 EGO27262.1 - 0.076 12.3 0.2 0.38 10.0 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EGO27262.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_S7e PF01251.18 EGO27263.1 - 5.5e-87 290.3 3.6 6.3e-87 290.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_1 PF00515.28 EGO27264.1 - 9.9e-11 41.0 4.1 0.013 15.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO27264.1 - 1e-08 34.7 2.7 0.035 14.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO27264.1 - 0.00034 20.6 0.5 0.031 14.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO27264.1 - 0.0011 19.6 0.1 0.058 14.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO27264.1 - 0.0012 19.3 0.1 0.31 11.6 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO27264.1 - 0.011 16.5 0.0 6.8 7.8 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO27264.1 - 0.017 15.1 0.2 7.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO27264.1 - 0.018 15.3 2.2 3.1 8.2 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat ERK-JNK_inhib PF15002.6 EGO27264.1 - 0.29 10.8 4.8 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor DAO PF01266.24 EGO27265.1 - 1.1e-51 176.5 0.0 1.4e-51 176.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO27265.1 - 9.1e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO27265.1 - 0.0079 15.5 0.0 0.095 11.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EGO27265.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase FAD_oxidored PF12831.7 EGO27265.1 - 0.032 13.6 0.0 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO27265.1 - 0.21 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.15 EGO27265.1 - 0.24 9.9 0.0 0.63 8.5 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) SH3_1 PF00018.28 EGO27266.1 - 6.5e-22 76.9 0.0 6.6e-11 41.6 0.0 3.1 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGO27266.1 - 5.7e-17 61.2 0.1 6.6e-09 35.3 0.0 3.2 4 0 0 4 4 4 2 Variant SH3 domain SH3_9 PF14604.6 EGO27266.1 - 4e-16 58.6 0.0 9.6e-08 31.8 0.0 3.2 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EGO27266.1 - 3.4e-07 30.2 0.0 8.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 PX domain Ribosomal_L12 PF00542.19 EGO27267.1 - 9.2e-23 80.4 2.7 9.2e-23 80.4 2.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain CDC37_C PF08564.10 EGO27267.1 - 0.11 12.7 1.1 0.27 11.4 1.2 1.6 1 1 0 1 1 1 0 Cdc37 C terminal domain TssN PF17555.2 EGO27269.1 - 0.8 9.0 3.6 0.44 9.9 0.7 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN p450 PF00067.22 EGO27270.1 - 4.8e-67 226.7 0.0 5.3e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 EGO27270.1 - 0.17 11.5 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) URO-D PF01208.17 EGO27273.1 - 1.6e-125 418.9 0.0 1.8e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DSPn PF14671.6 EGO27274.1 - 1.6e-39 135.6 0.0 6.6e-38 130.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGO27274.1 - 2.2e-14 53.4 0.0 4.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO27274.1 - 0.00023 20.8 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO27274.1 - 0.00066 19.8 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGO27274.1 - 0.074 13.0 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family ANTH PF07651.16 EGO27274.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Ank_2 PF12796.7 EGO27276.1 - 6.2e-18 65.2 0.1 4.9e-09 36.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGO27276.1 - 3.4e-16 58.9 0.8 1.8e-06 28.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EGO27276.1 - 2.2e-15 56.8 0.9 1.9e-09 37.9 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO27276.1 - 3.6e-13 49.4 0.0 6.3e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO27276.1 - 5.8e-12 44.7 0.3 0.00015 22.0 0.1 4.1 4 0 0 4 4 3 2 Ankyrin repeat KilA-N PF04383.13 EGO27276.1 - 5.3e-05 23.0 0.6 0.00076 19.3 0.1 2.8 2 1 0 2 2 2 1 KilA-N domain Acyl-CoA_dh_C PF12806.7 EGO27276.1 - 0.013 15.6 1.3 0.68 10.1 0.0 2.8 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Macoilin PF09726.9 EGO27276.1 - 0.086 11.4 14.8 0.26 9.8 14.8 1.7 1 1 0 1 1 1 0 Macoilin family CREPT PF16566.5 EGO27276.1 - 0.2 11.8 6.6 0.2 11.8 3.8 2.3 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour ZapA PF05164.13 EGO27276.1 - 0.22 12.0 6.6 0.39 11.2 4.6 2.3 2 0 0 2 2 2 0 Cell division protein ZapA Sec34 PF04136.15 EGO27276.1 - 0.35 10.7 5.6 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Sec34-like family KxDL PF10241.9 EGO27276.1 - 0.67 10.3 4.7 0.23 11.7 1.7 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein DUF2203 PF09969.9 EGO27276.1 - 1.6 9.5 5.5 5.9 7.6 1.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.8 EGO27276.1 - 2.2 8.5 8.8 0.59 10.4 3.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 EGO27276.1 - 5 5.5 7.5 8.3 4.8 7.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TolA_bind_tri PF16331.5 EGO27276.1 - 8.3 6.6 10.1 62 3.8 0.1 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Nucleoside_tran PF01733.18 EGO27278.1 - 7.1e-33 114.3 11.2 1.2e-32 113.5 11.2 1.3 1 0 0 1 1 1 1 Nucleoside transporter Nucleoside_tran PF01733.18 EGO27279.1 - 9.8e-36 123.7 9.9 9.8e-36 123.7 9.9 1.6 2 0 0 2 2 2 1 Nucleoside transporter ADH_N PF08240.12 EGO27280.1 - 7.3e-24 83.8 3.2 1.6e-23 82.7 3.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO27280.1 - 6.7e-19 68.2 0.3 1.4e-18 67.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO27280.1 - 0.00034 20.0 0.1 0.00058 19.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGO27280.1 - 0.0025 17.2 0.4 0.0046 16.3 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EGO27280.1 - 0.1 12.0 2.0 0.31 10.3 1.8 1.8 2 0 0 2 2 2 0 ThiF family ACBP PF00887.19 EGO27281.1 - 1.1e-22 80.1 0.0 1.5e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein MRP-S34 PF16053.5 EGO27283.1 - 2.9e-11 43.1 1.7 3.9e-11 42.7 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 DUF1663 PF07909.11 EGO27284.1 - 0.092 11.5 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) dUTPase PF00692.19 EGO27285.1 - 2.6e-42 143.6 0.0 3e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase Sugar_tr PF00083.24 EGO27286.1 - 5.5e-75 253.0 20.4 1.7e-50 172.2 2.3 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO27286.1 - 2.1e-18 66.4 34.4 1.5e-11 43.9 13.8 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily DUF2530 PF10745.9 EGO27286.1 - 0.013 15.7 0.4 0.013 15.7 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) UNC-93 PF05978.16 EGO27286.1 - 1.1 8.9 12.9 0.63 9.7 3.5 3.3 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 DUF1201 PF06716.11 EGO27286.1 - 7.4 6.7 11.8 1.4 9.0 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) adh_short_C2 PF13561.6 EGO27287.1 - 4.5e-64 216.2 0.1 5.4e-64 215.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO27287.1 - 2.6e-45 154.3 0.1 3.2e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO27287.1 - 4.8e-05 23.3 0.7 6.1e-05 23.0 0.1 1.4 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 EGO27287.1 - 0.0083 16.0 0.8 0.014 15.3 0.2 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EGO27287.1 - 0.023 15.4 0.0 0.043 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF962 PF06127.11 EGO27288.1 - 8.2e-22 77.1 2.0 3.2e-21 75.2 2.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DiS_P_DiS PF06750.13 EGO27291.1 - 0.044 13.9 2.3 0.07 13.3 2.3 1.3 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF2428 PF10350.9 EGO27291.1 - 0.11 11.7 0.9 0.18 11.0 0.9 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) RR_TM4-6 PF06459.12 EGO27291.1 - 0.21 11.4 11.4 0.29 10.9 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MTP18 PF10558.9 EGO27292.1 - 2.2e-65 219.8 6.4 3.2e-64 216.0 6.4 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF5353 PF17304.2 EGO27292.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5353) IF-2B PF01008.17 EGO27293.1 - 4.1e-86 288.7 0.2 5e-86 288.4 0.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family XRN_N PF03159.18 EGO27294.1 - 1.1e-101 339.4 0.0 1.3e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 EGO27294.1 - 0.00015 21.7 3.5 0.00026 20.9 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO27294.1 - 0.079 12.8 1.9 0.13 12.1 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO27294.1 - 0.11 12.4 1.2 0.19 11.8 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.22 EGO27295.1 - 4.8e-60 203.6 0.0 5.4e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C62 PF12380.8 EGO27295.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase Roughex PF06020.11 EGO27296.1 - 0.012 14.7 0.0 0.013 14.6 0.0 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Thy1 PF02511.15 EGO27296.1 - 0.09 12.6 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF5078 PF16877.5 EGO27296.1 - 0.097 13.1 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) Longin PF13774.6 EGO27297.1 - 1.5e-25 89.1 0.0 2.2e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGO27297.1 - 1.4e-16 60.1 0.2 2.3e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Sec_GG PF07549.14 EGO27299.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Retrotrans_gag PF03732.17 EGO27300.1 - 2e-08 34.4 0.6 2.3e-08 34.2 0.6 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 EGO27301.1 - 8e-06 26.3 0.0 9.1e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO27301.1 - 2.5e-05 24.1 0.0 2.6e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO27301.1 - 0.00016 22.3 0.0 0.00019 22.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 EGO27302.1 - 0.68 10.1 19.5 5.4 7.3 8.6 3.3 2 1 0 2 2 2 0 Zinc knuckle IPK PF03770.16 EGO27303.1 - 4.6e-50 170.2 0.0 8.5e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase UCR_UQCRX_QCR9 PF05365.12 EGO27304.1 - 3.3e-17 62.2 5.7 4.3e-17 61.8 5.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Flavokinase PF01687.17 EGO27305.1 - 1.4e-32 112.3 0.0 1.8e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Xol-1_N PF09108.10 EGO27305.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal Myb_DNA-binding PF00249.31 EGO27306.1 - 4.7e-40 135.5 4.9 1e-11 44.8 0.0 5.4 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO27306.1 - 3.8e-33 113.5 0.8 3.2e-14 52.9 0.0 5.3 2 2 3 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 EGO27306.1 - 8.5e-05 22.6 0.1 0.38 10.8 0.0 2.9 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 EGO27306.1 - 0.0013 19.1 12.0 0.28 11.6 0.7 5.4 4 3 0 4 4 4 2 Myb/SANT-like DNA-binding domain MamL-1 PF09596.10 EGO27306.1 - 0.0048 17.1 0.9 0.03 14.6 0.1 2.5 2 0 0 2 2 2 1 MamL-1 domain Rap1_C PF11626.8 EGO27306.1 - 0.012 15.6 0.0 0.31 11.2 0.0 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DNA_meth_N PF18284.1 EGO27306.1 - 0.14 12.1 0.1 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 DNA methylase N-terminal domain TMEM208_SND2 PF05620.11 EGO27307.1 - 8.3e-55 185.1 0.0 9.3e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 RRP36 PF06102.12 EGO27308.1 - 1.9 8.5 11.1 2.7 7.9 11.1 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 G_path_suppress PF15991.5 EGO27308.1 - 6.4 6.8 13.6 9.1 6.3 13.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor adh_short PF00106.25 EGO27311.1 - 1.1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO27311.1 - 2.5e-05 23.9 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MT-A70 PF05063.14 EGO27312.1 - 3.2e-57 193.2 0.1 4.5e-57 192.7 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Abhydrolase_1 PF00561.20 EGO27313.1 - 6.3e-25 88.3 0.0 2.5e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO27313.1 - 1.3e-19 70.4 0.0 4.9e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO27313.1 - 2.3e-16 61.0 1.5 1.5e-15 58.4 1.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGO27313.1 - 1.3e-05 25.0 0.1 4.6e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 EGO27313.1 - 1.7e-05 24.5 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EGO27313.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.13 EGO27313.1 - 0.0033 17.3 0.0 0.061 13.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 EGO27313.1 - 0.0036 16.0 0.0 0.0088 14.8 0.0 1.5 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.11 EGO27313.1 - 0.0053 16.7 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGO27313.1 - 0.033 13.7 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 EGO27313.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 EGO27313.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Aminotran_1_2 PF00155.21 EGO27314.1 - 3.2e-75 253.6 0.0 4.4e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO27314.1 - 0.00012 20.8 0.0 0.00019 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGO27314.1 - 0.00015 20.8 0.0 0.0003 19.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Ldl_recept_b PF00058.17 EGO27314.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor repeat class B YqeY PF09424.10 EGO27314.1 - 0.16 12.0 0.4 0.33 11.0 0.1 1.6 2 0 0 2 2 2 0 Yqey-like protein Preseq_ALAS PF09029.10 EGO27314.1 - 0.6 10.6 10.2 42 4.7 10.2 3.1 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence Arf PF00025.21 EGO27315.1 - 5.7e-71 237.5 0.0 6.6e-71 237.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO27315.1 - 1.7e-14 53.7 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGO27315.1 - 4.2e-13 49.6 0.0 5.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGO27315.1 - 5.9e-13 48.7 0.0 4.9e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGO27315.1 - 8.6e-10 38.4 0.0 9.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGO27315.1 - 9.1e-09 35.0 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO27315.1 - 0.00077 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 EGO27316.1 - 1.9e-23 82.3 14.9 0.0003 21.5 1.6 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27316.1 - 1.4e-08 34.9 0.0 1.7e-06 28.3 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DKNYY PF13644.6 EGO27317.1 - 0.0038 18.0 0.9 0.0041 17.9 0.9 1.1 1 0 0 1 1 1 1 DKNYY family DUF4939 PF16297.5 EGO27317.1 - 0.026 14.4 0.0 0.027 14.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RVP_2 PF08284.11 EGO27318.1 - 9.3e-06 25.4 0.0 1e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO27318.1 - 3.1e-05 24.4 0.0 3.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO27318.1 - 0.00037 21.1 0.0 0.00048 20.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF1771 PF08590.10 EGO27321.1 - 0.057 13.8 1.0 0.16 12.4 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_4 PF14392.6 EGO27321.1 - 0.076 12.8 1.6 0.19 11.5 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Pol_alpha_B_N PF08418.10 EGO27321.1 - 0.1 12.5 1.2 0.14 12.1 1.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-RING_10 PF16685.5 EGO27321.1 - 2.2 8.5 8.7 0.87 9.8 4.2 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Gcd10p PF04189.13 EGO27322.1 - 6.8e-56 189.6 0.0 1.7e-38 132.5 0.0 2.1 2 0 0 2 2 2 2 Gcd10p family Iso_dh PF00180.20 EGO27323.1 - 3.2e-98 329.1 0.0 3.8e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HNH_2 PF13391.6 EGO27325.1 - 0.012 15.8 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease MerR-DNA-bind PF09278.11 EGO27326.1 - 0.00014 22.3 6.6 4.4 7.9 0.0 3.4 3 0 0 3 3 3 3 MerR, DNA binding AIP3 PF03915.13 EGO27326.1 - 0.0055 15.9 1.3 0.007 15.5 1.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Atg14 PF10186.9 EGO27326.1 - 0.0073 15.4 3.1 0.01 14.9 3.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MPS2 PF17060.5 EGO27326.1 - 0.13 11.5 1.0 0.17 11.1 1.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 FUSC PF04632.12 EGO27326.1 - 0.19 10.2 4.7 0.23 10.0 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family 7tm_7 PF08395.12 EGO27326.1 - 0.19 10.9 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor CENP-H PF05837.12 EGO27326.1 - 0.46 10.9 7.1 1 9.8 6.4 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Fmp27_WPPW PF10359.9 EGO27326.1 - 3.9 6.2 6.1 5.9 5.6 5.9 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.12 EGO27327.1 - 2.9e-09 37.0 0.2 8.2e-07 29.1 0.0 3.0 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 EGO27327.1 - 0.00017 21.4 0.2 0.031 14.2 0.0 3.4 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 EGO27327.1 - 0.0025 17.3 0.0 0.089 12.4 0.0 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EGO27327.1 - 0.0098 16.4 0.1 0.12 12.9 0.0 2.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_micro PF17007.5 EGO27327.1 - 0.06 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 HTH-like MarR PF01047.22 EGO27327.1 - 0.068 13.1 0.1 3.6 7.6 0.0 3.2 3 0 0 3 3 3 0 MarR family Helicase_C PF00271.31 EGO27329.1 - 2e-07 31.3 0.0 3.1e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Radial_spoke_3 PF06098.11 EGO27329.1 - 0.16 11.2 0.2 0.26 10.5 0.2 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Minor_tail_Z PF06763.11 EGO27330.1 - 0.061 13.1 0.5 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) DUF3381 PF11861.8 EGO27332.1 - 0.038 13.8 1.0 0.06 13.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) zf-CCHC_3 PF13917.6 EGO27333.1 - 1.1e-06 28.5 1.2 2.3e-06 27.4 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO27333.1 - 9.5e-06 25.5 5.1 1.4e-05 24.9 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO27333.1 - 0.037 13.5 0.7 0.067 12.7 0.7 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain Alpha_kinase PF02816.18 EGO27334.1 - 5.2e-09 36.5 0.0 6.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Spc24 PF08286.11 EGO27335.1 - 0.041 14.1 3.3 0.086 13.1 3.3 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ING PF12998.7 EGO27335.1 - 0.089 13.4 4.3 0.18 12.4 3.8 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Tweety PF04906.13 EGO27335.1 - 0.11 11.1 0.3 0.16 10.6 0.3 1.2 1 0 0 1 1 1 0 Tweety LMBR1 PF04791.16 EGO27335.1 - 0.29 10.0 0.3 0.3 9.9 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 EGO27335.1 - 3.8 8.2 10.3 0.3 11.8 3.0 2.6 2 1 1 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 EGO27335.1 - 6.6 6.2 9.0 0.24 10.9 2.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Amidohydro_1 PF01979.20 EGO27336.1 - 5.7e-06 25.9 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EGO27336.1 - 4.2e-05 23.5 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Kinesin PF00225.23 EGO27337.1 - 2.9e-108 361.7 0.0 3.3e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO27337.1 - 3.9e-24 85.3 0.0 6.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding PRAI PF00697.22 EGO27337.1 - 0.13 12.0 0.4 0.2 11.4 0.4 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase EMP24_GP25L PF01105.24 EGO27338.1 - 2.4e-50 171.0 0.4 2.8e-50 170.8 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 EGO27339.1 - 1e-49 167.8 0.5 1e-49 167.8 0.5 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 EGO27339.1 - 0.00026 20.9 0.4 0.0015 18.4 0.4 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 EGO27339.1 - 0.00036 20.2 0.8 0.00047 19.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CK2S PF15011.6 EGO27339.1 - 0.012 15.6 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate GOLD_2 PF13897.6 EGO27339.1 - 7.3 7.1 7.1 4.4 7.8 4.3 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking AAA_2 PF07724.14 EGO27340.1 - 1.4e-36 126.2 0.0 2.2e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGO27340.1 - 4.3e-14 53.1 0.0 7.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGO27340.1 - 2.7e-10 40.1 0.0 5.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGO27340.1 - 1.2e-05 25.3 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO27340.1 - 6.8e-05 23.2 0.1 0.00078 19.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGO27340.1 - 0.0001 21.8 0.0 0.0031 16.9 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGO27340.1 - 0.0016 18.9 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGO27340.1 - 0.0059 16.4 0.2 0.13 12.0 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EGO27340.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGO27340.1 - 0.0089 15.8 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 EGO27340.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 EGO27340.1 - 0.012 15.3 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 EGO27340.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EGO27340.1 - 0.019 14.1 0.0 0.083 12.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 EGO27340.1 - 0.026 15.0 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGO27340.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EGO27340.1 - 0.042 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 EGO27340.1 - 0.043 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.6 EGO27340.1 - 0.044 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGO27340.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO27340.1 - 0.075 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 EGO27340.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EGO27340.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EGO27340.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGO27340.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_3 PF07726.11 EGO27340.1 - 0.16 11.9 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EGO27340.1 - 0.24 10.5 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Cactin_mid PF10312.9 EGO27341.1 - 4.6e-66 222.3 4.9 4.6e-66 222.3 4.9 2.9 4 0 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EGO27341.1 - 3.2e-60 201.6 6.8 7e-60 200.5 6.8 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EGO27341.1 - 0.2 12.0 1.9 0.64 10.4 0.0 2.8 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Cyclin PF08613.11 EGO27342.1 - 0.024 15.0 0.1 0.039 14.3 0.1 1.4 1 0 0 1 1 1 0 Cyclin ThiF PF00899.21 EGO27343.1 - 8e-106 352.9 0.0 2.3e-70 236.7 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGO27343.1 - 1.4e-88 297.1 0.0 2.5e-88 296.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGO27343.1 - 2.9e-35 120.3 0.1 5.7e-35 119.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EGO27343.1 - 5e-31 107.3 0.2 1.2e-30 106.1 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EGO27343.1 - 8.8e-26 89.9 0.4 3.8e-25 87.9 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Glyco_hydro_92 PF07971.12 EGO27344.1 - 3.1e-145 484.7 5.3 3.7e-145 484.4 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGO27344.1 - 3e-61 207.3 4.6 5.6e-61 206.5 4.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GHBP PF12772.7 EGO27344.1 - 0.026 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Growth hormone receptor binding DUF3402 PF11882.8 EGO27347.1 - 1.1e-114 384.1 0.0 1.1e-56 192.9 3.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 EGO27347.1 - 1.5e-39 135.9 0.0 3.2e-36 125.0 0.0 2.3 1 1 1 2 2 2 2 N1221-like protein CBM_X2 PF03442.14 EGO27350.1 - 0.017 15.2 0.0 0.018 15.2 0.0 1.0 1 0 0 1 1 1 0 Carbohydrate binding domain X2 APC_15aa PF05972.11 EGO27350.1 - 0.087 13.1 0.6 0.16 12.3 0.6 1.4 1 0 0 1 1 1 0 APC 15 residue motif Diphthamide_syn PF01866.17 EGO27351.1 - 1.3e-94 317.1 0.0 1.8e-55 188.5 0.0 2.8 2 1 0 2 2 2 2 Putative diphthamide synthesis protein NPC1_N PF16414.5 EGO27352.1 - 2.1e-82 276.4 8.4 3.5e-82 275.6 8.4 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EGO27352.1 - 1.2e-70 238.6 5.5 3.2e-37 128.1 0.1 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 EGO27352.1 - 3.8e-45 153.4 19.0 1.5e-24 86.5 0.2 4.0 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EGO27352.1 - 5.9e-09 34.2 3.4 1.3e-08 33.1 3.4 1.5 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 EGO27352.1 - 0.00031 20.7 0.8 0.00068 19.6 0.8 1.5 1 0 0 1 1 1 1 Folate receptor family Glyoxalase_2 PF12681.7 EGO27352.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Integrase_Zn PF02022.19 EGO27352.1 - 0.23 11.4 0.5 0.49 10.4 0.5 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain RRM_1 PF00076.22 EGO27353.1 - 1.4e-12 47.3 0.0 2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO27353.1 - 4.4e-10 39.2 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO27353.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif zf-H2C2_2 PF13465.6 EGO27354.1 - 1.5e-06 28.3 11.3 0.00067 20.0 1.8 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGO27354.1 - 0.0012 19.1 0.8 0.0012 19.1 0.8 3.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO27354.1 - 0.0038 17.9 16.5 0.072 14.0 0.5 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 EGO27354.1 - 0.63 10.5 6.1 32 5.1 0.8 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NAD_binding_1 PF00175.21 EGO27355.1 - 5.4e-10 39.9 0.0 1.4e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGO27355.1 - 2.6e-09 37.3 0.0 4.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGO27355.1 - 0.00053 20.1 0.0 0.016 15.4 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Med18 PF09637.10 EGO27357.1 - 2.7e-06 27.4 0.0 0.00012 22.0 0.0 2.0 1 1 1 2 2 2 2 Med18 protein CIAPIN1 PF05093.13 EGO27358.1 - 2.2e-31 108.3 4.0 3.8e-31 107.6 4.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EGO27358.1 - 4.1e-08 33.5 0.0 6.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Forkhead PF00250.18 EGO27359.1 - 1e-30 105.8 0.0 1.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Pkinase PF00069.25 EGO27362.1 - 3.4e-68 229.9 0.0 4.4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27362.1 - 6e-30 104.4 0.0 8.3e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGO27362.1 - 5.6e-19 68.6 0.3 5.6e-19 68.6 0.3 2.7 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 EGO27362.1 - 1.6e-09 38.0 0.1 1.2e-06 28.7 0.1 2.4 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 EGO27362.1 - 3.7e-09 36.3 0.1 2.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGO27362.1 - 1.5e-06 27.5 0.0 3.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGO27362.1 - 0.00088 19.0 0.1 0.23 11.1 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGO27362.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO27362.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Suc_Fer-like PF06999.12 EGO27363.1 - 1.8e-47 161.8 0.1 2.7e-47 161.2 0.1 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MRP-S26 PF14943.6 EGO27364.1 - 0.013 15.4 0.5 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Retrotrans_gag PF03732.17 EGO27365.1 - 4.8e-06 26.8 0.2 4.8e-06 26.8 0.2 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein DZR PF12773.7 EGO27366.1 - 0.21 11.6 7.6 0.41 10.7 7.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Acyl-CoA_dh_1 PF00441.24 EGO27367.1 - 2.4e-29 102.5 0.3 3.9e-29 101.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO27367.1 - 7.5e-18 64.5 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO27367.1 - 4.9e-11 43.0 0.1 9.9e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO27367.1 - 2.7e-10 40.9 0.0 5.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Fungal_trans PF04082.18 EGO27368.1 - 2.3e-33 115.4 0.0 3.7e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO27368.1 - 4e-07 30.0 15.2 7.5e-07 29.2 15.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 EGO27369.1 - 3.1e-17 62.1 0.0 1.2e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 EGO27369.1 - 6.7e-13 48.5 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 IMD PF08397.11 EGO27370.1 - 1.5e-05 24.5 3.8 1.5e-05 24.5 3.8 1.4 2 0 0 2 2 2 1 IRSp53/MIM homology domain ARD PF03079.14 EGO27370.1 - 0.0034 17.6 1.9 0.006 16.8 1.9 1.3 1 0 0 1 1 1 1 ARD/ARD' family Spc7 PF08317.11 EGO27370.1 - 0.0055 15.6 3.4 0.0086 15.0 3.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein OmpH PF03938.14 EGO27370.1 - 0.025 14.9 3.7 0.025 14.9 3.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_int_SAM_2 PF12834.7 EGO27370.1 - 0.1 13.3 0.5 0.23 12.2 0.5 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal End3 PF12761.7 EGO27370.1 - 0.16 12.1 4.3 0.28 11.3 4.3 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 BLOC1_2 PF10046.9 EGO27370.1 - 0.4 11.0 6.6 0.2 12.0 2.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mak16 PF04874.14 EGO27370.1 - 0.4 11.3 4.1 8 7.1 1.8 2.4 1 1 1 2 2 2 0 Mak16 protein C-terminal region DUF4407 PF14362.6 EGO27370.1 - 0.56 9.5 3.2 0.64 9.3 2.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EGO27370.1 - 1.2 9.5 5.7 2.4 8.5 5.7 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain tRNA-synt_2 PF00152.20 EGO27371.1 - 3.2e-85 286.0 0.0 6.6e-85 284.9 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO27371.1 - 2.5e-07 30.6 0.0 5.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ACPS PF01648.20 EGO27373.1 - 3.7e-11 43.2 0.0 8.5e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.24 EGO27374.1 - 2e-12 47.0 0.0 2.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGO27374.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase CBFD_NFYB_HMF PF00808.23 EGO27375.1 - 0.001 19.3 0.0 0.0012 19.1 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LSM PF01423.22 EGO27376.1 - 1.5e-21 75.9 0.0 1.6e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO27376.1 - 0.0044 17.1 0.0 0.0052 16.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain TMEM100 PF16311.5 EGO27380.1 - 0.081 12.5 6.1 0.57 9.8 1.8 2.4 2 0 0 2 2 2 0 Transmembrane protein 100 PilS PF08805.11 EGO27380.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 PilS N terminal Actin PF00022.19 EGO27381.1 - 2.3e-116 388.8 0.0 2.6e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGO27381.1 - 3e-05 23.0 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Tmpp129 PF10272.9 EGO27382.1 - 0.13 11.5 0.8 0.2 11.0 0.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor FlxA PF14282.6 EGO27382.1 - 3.7 7.6 16.4 0.78 9.8 12.3 2.0 2 0 0 2 2 2 0 FlxA-like protein Sedlin_N PF04628.13 EGO27383.1 - 3e-35 121.2 0.1 1.4e-34 119.1 0.1 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGO27383.1 - 4.9e-08 33.0 0.0 8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Rhomboid PF01694.22 EGO27384.1 - 8.2e-25 87.6 9.2 8.2e-25 87.6 9.2 1.6 2 0 0 2 2 2 1 Rhomboid family SurE PF01975.17 EGO27385.1 - 3.2e-06 27.0 0.0 4e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Survival protein SurE Rdx PF10262.9 EGO27387.1 - 1.2e-25 89.5 0.0 1.5e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Rdx family AAA PF00004.29 EGO27388.1 - 8.1e-31 107.2 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO27388.1 - 9.3e-08 32.4 0.1 1.4e-06 28.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO27388.1 - 3.7e-07 30.7 0.0 9.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGO27388.1 - 1.5e-05 25.5 0.0 3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGO27388.1 - 3.2e-05 24.1 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGO27388.1 - 0.00022 21.4 0.0 0.00044 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGO27388.1 - 0.00025 21.1 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO27388.1 - 0.00052 19.9 0.1 0.0011 18.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGO27388.1 - 0.00059 19.1 0.1 0.011 14.9 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EGO27388.1 - 0.00083 19.3 0.1 0.6 10.0 0.1 2.2 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGO27388.1 - 0.0013 18.4 0.3 0.23 11.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 EGO27388.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EGO27388.1 - 0.0024 17.9 0.1 0.0058 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO27388.1 - 0.0027 17.4 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGO27388.1 - 0.0028 17.9 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGO27388.1 - 0.0031 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 EGO27388.1 - 0.0038 17.6 0.0 0.0094 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 EGO27388.1 - 0.0039 16.9 0.0 0.0084 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EGO27388.1 - 0.0044 17.0 0.1 0.0093 15.9 0.1 1.8 1 1 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.18 EGO27388.1 - 0.0049 16.6 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EGO27388.1 - 0.0078 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGO27388.1 - 0.0084 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EGO27388.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO27388.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 EGO27388.1 - 0.017 15.6 0.1 0.17 12.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO27388.1 - 0.033 14.7 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 EGO27388.1 - 0.035 14.4 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGO27388.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 EGO27388.1 - 0.045 13.0 0.1 5.2 6.2 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Rad17 PF03215.15 EGO27388.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_13 PF13166.6 EGO27388.1 - 0.063 11.9 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGO27388.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EGO27388.1 - 0.095 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 EGO27388.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein CPT PF07931.12 EGO27388.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 EGO27388.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EGO27388.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 EGO27388.1 - 0.2 11.0 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 KaiC PPR_2 PF13041.6 EGO27389.1 - 2.2e-05 24.6 0.0 0.067 13.4 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 EGO27389.1 - 0.00054 20.0 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain TPMT PF05724.11 EGO27390.1 - 1.5e-23 83.6 0.0 1.9e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EGO27390.1 - 1.2e-07 32.3 0.0 1.8e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO27390.1 - 1.5e-06 28.7 0.0 2.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO27390.1 - 5.4e-06 27.1 0.0 9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO27390.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO27390.1 - 0.028 14.2 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 EGO27391.1 - 2e-34 119.2 0.0 2.5e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EGO27391.1 - 9.7e-09 35.8 0.0 1.4e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO27391.1 - 3.3e-07 30.8 0.0 4.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO27391.1 - 8.9e-06 25.6 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO27391.1 - 0.00042 20.2 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO27391.1 - 0.0046 17.7 0.0 0.0072 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain LSM PF01423.22 EGO27392.1 - 3e-19 68.5 0.0 3.3e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGO27392.1 - 0.071 12.8 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Hfq protein MDM10 PF12519.8 EGO27394.1 - 3.2e-100 336.2 1.1 1.5e-88 297.7 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EGO27394.1 - 0.066 12.7 0.0 30 3.9 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic porin Pkinase PF00069.25 EGO27395.1 - 2.5e-28 99.2 0.0 1.8e-27 96.3 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27395.1 - 2.4e-26 92.6 0.0 6.3e-26 91.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Gag_p17 PF00540.18 EGO27395.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) p450 PF00067.22 EGO27396.1 - 3.9e-71 240.2 0.0 4.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 EGO27399.1 - 4.3e-19 68.4 1.9 7.7e-19 67.6 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EGO27399.1 - 0.0012 19.2 1.4 0.002 18.5 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF1269 PF06897.12 EGO27399.1 - 8.1 6.8 7.5 13 6.2 2.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) NUFIP1 PF10453.9 EGO27401.1 - 0.024 14.5 0.3 0.024 14.5 0.3 1.6 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Hfq PF17209.3 EGO27401.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF3425 PF11905.8 EGO27402.1 - 1.3e-14 54.3 0.2 6e-13 48.9 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EGO27402.1 - 8.8e-08 32.1 7.9 4.2e-07 30.0 8.0 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO27402.1 - 0.013 15.6 10.9 0.015 15.4 5.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Glyco_hydro_125 PF06824.11 EGO27403.1 - 2e-154 514.5 1.6 2.3e-154 514.3 1.6 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aconitase PF00330.20 EGO27405.1 - 1.4e-157 525.4 0.1 1.7e-157 525.2 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO27405.1 - 3.7e-39 134.1 0.0 6.2e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.17 EGO27406.1 - 4.1e-17 62.2 14.7 6e-17 61.7 14.7 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Tau95 PF09734.9 EGO27407.1 - 1.5e-40 139.3 0.4 1.5e-40 139.3 0.4 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EGO27407.1 - 3.2e-27 95.3 0.0 9.4e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 Tau95 Triple barrel domain Sld5 PF05916.11 EGO27409.1 - 2.1e-06 28.1 0.0 2.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein PapC_C PF13953.6 EGO27409.1 - 0.093 12.6 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 PapC C-terminal domain DNA_RNApol_7kD PF03604.13 EGO27410.1 - 9.1e-18 63.6 8.4 1.2e-17 63.3 8.4 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 EGO27410.1 - 0.0019 17.9 0.3 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 EGO27410.1 - 0.0038 17.2 0.5 0.0054 16.7 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGO27410.1 - 0.0053 16.8 2.8 0.011 15.8 2.8 1.5 1 1 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 EGO27410.1 - 0.0074 16.3 0.4 0.0084 16.1 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 EGO27410.1 - 0.011 15.4 1.7 0.03 14.0 1.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-ISL3 PF14690.6 EGO27410.1 - 0.012 16.3 1.9 0.057 14.1 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.6 EGO27410.1 - 0.012 16.1 3.2 0.28 11.7 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain MCM_OB PF17207.3 EGO27410.1 - 0.012 15.4 0.6 0.014 15.3 0.6 1.1 1 0 0 1 1 1 0 MCM OB domain zf-C3HC PF07967.13 EGO27410.1 - 0.013 15.6 0.0 0.013 15.5 0.0 1.0 1 0 0 1 1 1 0 C3HC zinc finger-like OrfB_Zn_ribbon PF07282.11 EGO27410.1 - 0.02 14.8 0.9 0.026 14.4 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-trcl PF13451.6 EGO27410.1 - 0.022 14.6 5.7 0.37 10.7 0.2 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zinc-ribbon_6 PF10005.9 EGO27410.1 - 0.025 15.2 0.2 0.032 14.9 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EGO27410.1 - 0.038 13.5 2.6 0.55 9.8 0.1 2.2 1 1 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.18 EGO27410.1 - 0.1 12.5 1.8 3.4 7.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF35_N PF12172.8 EGO27410.1 - 0.12 12.3 1.7 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rubredoxin_2 PF18073.1 EGO27410.1 - 0.13 12.0 4.0 5.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Sec23_Sec24 PF04810.15 EGO27410.1 - 0.14 12.3 3.1 9.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 EGO27410.1 - 0.14 11.7 2.6 0.74 9.3 2.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EGO27410.1 - 0.15 12.0 3.1 2.3 8.2 3.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf_UBZ PF18439.1 EGO27410.1 - 0.16 11.6 2.3 6.4 6.5 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-NADH-PPase PF09297.11 EGO27410.1 - 0.22 11.2 3.4 0.63 9.8 3.4 1.7 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-dskA_traR PF01258.17 EGO27410.1 - 0.87 9.6 7.4 1.2 9.1 0.4 2.6 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Thg1C PF14413.6 EGO27411.1 - 0.09 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Thg1 C terminal domain Ribosomal_L11 PF00298.19 EGO27413.1 - 7.5e-30 103.3 0.2 1.1e-29 102.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EGO27413.1 - 2.4e-26 91.4 0.3 3.5e-26 90.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Inh PF02974.14 EGO27414.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh MyTH4 PF00784.17 EGO27415.1 - 0.11 13.0 0.0 0.64 10.5 0.0 2.0 1 1 1 2 2 2 0 MyTH4 domain Glyco_hydro_cc PF11790.8 EGO27416.1 - 7.3e-51 173.0 6.0 8.2e-51 172.9 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.22 EGO27417.1 - 1e-26 92.5 0.0 4.4e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 EGO27417.1 - 3e-21 74.9 1.6 6.1e-21 74.0 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EGO27417.1 - 1.4e-05 24.9 0.8 3.7e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.6 EGO27417.1 - 0.0067 16.0 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACT PF01842.25 EGO27417.1 - 0.019 14.7 0.0 0.069 12.9 0.0 2.0 1 0 0 1 1 1 0 ACT domain DbpA PF03880.15 EGO27417.1 - 0.049 13.6 0.1 11 6.1 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain DUF4944 PF16302.5 EGO27417.1 - 0.081 13.0 0.2 4.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) Totivirus_coat PF05518.11 EGO27417.1 - 2.8 5.9 15.3 0.072 11.1 6.5 2.0 2 0 0 2 2 2 0 Totivirus coat protein Myb_DNA-bind_4 PF13837.6 EGO27419.1 - 1.9e-06 28.1 0.0 3.5e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGO27419.1 - 1.8e-05 25.6 0.0 3.1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO27419.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Aminotran_1_2 PF00155.21 EGO27421.1 - 7.6e-63 212.9 0.0 8.9e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO27421.1 - 0.00016 20.3 0.0 0.00031 19.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGO27421.1 - 0.00021 20.7 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGO27421.1 - 0.0043 16.4 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGO27421.1 - 0.0081 15.2 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Thiolase_N PF00108.23 EGO27422.1 - 3.3e-85 285.6 2.1 4.4e-85 285.2 2.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO27422.1 - 1.4e-38 131.3 0.4 1.4e-38 131.3 0.4 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO27422.1 - 0.0003 20.4 2.6 0.03 13.9 2.1 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGO27422.1 - 0.025 14.4 0.8 1 9.2 0.4 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III COX7C PF02935.16 EGO27423.1 - 4.3e-09 36.5 4.0 4.3e-09 36.5 4.0 1.5 1 1 1 2 2 2 1 Cytochrome c oxidase subunit VIIc Ribonuclease_3 PF00636.26 EGO27424.1 - 2.5e-46 156.6 0.0 1.6e-22 80.1 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGO27424.1 - 1.8e-28 99.2 0.0 3.3e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.14 EGO27424.1 - 1e-11 44.8 0.0 2.1e-10 40.6 0.0 3.1 3 0 0 3 3 3 1 Dicer dimerisation domain PAZ PF02170.22 EGO27424.1 - 1.7e-08 34.4 0.0 3.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 PAZ domain Helicase_C PF00271.31 EGO27424.1 - 0.033 14.5 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain aGPT-Pplase1 PF18723.1 EGO27425.1 - 5.1e-107 357.5 0.0 6.2e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 EGO27425.1 - 3.8e-11 42.7 0.0 1.2e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S10 PF00338.22 EGO27425.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e UBX PF00789.20 EGO27425.1 - 0.048 13.9 0.0 15 5.8 0.0 3.2 3 0 0 3 3 3 0 UBX domain Q_salvage PF10343.9 EGO27426.1 - 0.16 11.5 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family ubiquitin PF00240.23 EGO27427.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family GxGYxYP_C PF14323.6 EGO27427.1 - 0.11 12.3 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain Pkinase PF00069.25 EGO27428.1 - 7.5e-69 232.0 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27428.1 - 5.3e-31 107.8 0.0 1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO27428.1 - 0.019 13.9 0.1 0.071 12.0 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EGO27428.1 - 0.041 13.2 0.0 0.098 12.0 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Med15 PF09606.10 EGO27428.1 - 0.065 11.9 29.6 0.088 11.5 29.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Bot1p PF12298.8 EGO27428.1 - 0.17 12.0 5.5 0.3 11.3 5.5 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein APH PF01636.23 EGO27428.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family PAT1 PF09770.9 EGO27428.1 - 7 4.8 15.3 8.7 4.5 15.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 cNMP_binding PF00027.29 EGO27429.1 - 7.6e-33 112.5 0.4 4.9e-15 55.4 0.1 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EGO27429.1 - 1.2e-11 44.0 0.1 2.8e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2672 PF10878.8 EGO27429.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) MFS_1 PF07690.16 EGO27431.1 - 9.3e-38 130.0 14.0 1.4e-36 126.2 15.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGO27431.1 - 4.7e-05 22.9 0.8 4.7e-05 22.9 0.8 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2109 PF09882.9 EGO27431.1 - 0.044 13.8 1.8 0.13 12.3 0.9 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Ytp1 PF10355.9 EGO27432.1 - 4.5e-100 334.4 2.7 8.1e-100 333.6 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGO27432.1 - 1.1e-14 54.1 4.9 1.1e-14 54.1 4.9 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) UbiA PF01040.18 EGO27433.1 - 2.2e-49 168.1 18.6 3e-49 167.6 18.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Rho_GDI PF02115.17 EGO27434.1 - 7e-54 182.5 0.0 8e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 EGO27434.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain zf-CCCH PF00642.24 EGO27435.1 - 0.0015 18.4 24.2 0.0065 16.4 3.1 3.8 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGO27435.1 - 2.6 7.9 16.8 0.45 10.4 3.2 3.5 2 1 1 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGO27435.1 - 3.3 7.9 20.2 1.1 9.4 2.0 4.1 4 0 0 4 4 4 0 Zinc finger domain Abhydrolase_6 PF12697.7 EGO27436.1 - 2.2e-10 41.5 0.3 2.9e-10 41.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO27436.1 - 1.2e-05 25.0 0.1 0.0095 15.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EGO27436.1 - 0.0003 20.5 0.0 0.00083 19.1 0.0 1.8 3 0 0 3 3 3 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGO27436.1 - 0.027 13.7 0.0 0.29 10.4 0.0 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 GFO_IDH_MocA PF01408.22 EGO27437.1 - 3.2e-18 66.7 0.2 5.8e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO27437.1 - 8.7e-06 25.7 0.9 0.00016 21.6 0.0 2.9 4 0 0 4 4 4 1 Oxidoreductase family, C-terminal alpha/beta domain DUF448 PF04296.13 EGO27438.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF448) Proteasome PF00227.26 EGO27439.1 - 1.4e-43 148.6 0.0 1.7e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 EGO27440.1 - 2e-48 164.4 0.0 2.5e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO27440.1 - 1.9e-13 49.8 0.1 3.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nup88 PF10168.9 EGO27441.1 - 4.9e-23 80.9 0.0 1.2e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 EGO27441.1 - 5.2e-05 23.4 5.5 0.00012 22.2 5.5 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 ANAPC4_WD40 PF12894.7 EGO27441.1 - 0.085 13.2 0.0 20 5.6 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S3Ae PF01015.18 EGO27442.1 - 4.5e-96 320.2 3.2 5.4e-96 320.0 3.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EGO27442.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region MFS_1 PF07690.16 EGO27443.1 - 7.9e-41 140.1 47.2 7.9e-41 140.1 47.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO27443.1 - 1.3e-06 27.5 2.7 1.3e-06 27.5 2.7 3.9 2 2 2 4 4 4 2 Sugar (and other) transporter MFS_3 PF05977.13 EGO27443.1 - 0.0036 15.8 6.6 0.0061 15.0 6.3 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector BacteriocIIc_cy PF12173.8 EGO27443.1 - 0.22 11.8 3.4 1.3 9.4 0.2 3.5 3 1 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like DEAD PF00270.29 EGO27444.1 - 3.9e-51 173.3 0.0 3.2e-50 170.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO27444.1 - 2.8e-26 92.0 0.0 1e-25 90.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO27444.1 - 0.0035 17.4 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NuDC PF16273.5 EGO27444.1 - 0.067 13.7 0.0 0.067 13.7 0.0 3.2 3 0 0 3 3 3 0 Nuclear distribution C domain CwsA PF10814.8 EGO27444.1 - 0.23 11.6 4.4 0.65 10.2 4.4 1.7 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA PI31_Prot_N PF11566.8 EGO27445.1 - 6.6e-40 136.6 0.0 9e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGO27445.1 - 8.5e-13 49.3 13.1 8.5e-13 49.3 13.1 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator Glyco_hydro_47 PF01532.20 EGO27446.1 - 2.6e-110 369.5 0.0 4.7e-110 368.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 EGO27446.1 - 3.2e-06 27.1 0.0 8.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 PA domain WD40 PF00400.32 EGO27447.1 - 1.4e-55 184.0 32.5 1.7e-07 31.8 0.2 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27447.1 - 8.3e-28 96.5 2.9 2.5e-05 24.5 0.0 9.4 5 3 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGO27447.1 - 4e-19 68.9 1.5 7.2e-19 68.1 1.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EGO27447.1 - 2.6e-09 36.5 3.0 0.00068 18.7 0.1 5.8 4 2 3 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGO27447.1 - 3.3e-07 29.4 7.9 0.0089 14.8 0.0 5.9 3 2 2 6 6 6 2 Nup133 N terminal like Nup160 PF11715.8 EGO27447.1 - 1.1e-06 27.6 3.4 1.5 7.3 0.0 5.3 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EGO27447.1 - 1.6e-06 27.7 0.0 0.11 11.8 0.0 4.4 4 1 1 5 5 5 2 WD40-like domain Utp21 PF04192.12 EGO27447.1 - 0.036 13.5 0.2 0.085 12.3 0.2 1.6 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain ELYS-bb PF16687.5 EGO27447.1 - 0.043 12.4 0.0 2 6.9 0.0 3.1 3 1 1 4 4 4 0 beta-propeller of ELYS nucleoporin CNH PF00780.22 EGO27447.1 - 0.048 13.3 0.0 6.6 6.3 0.0 3.0 3 0 0 3 3 3 0 CNH domain DNA_ligase_C PF17879.1 EGO27448.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA ligase C-terminal domain ATE_C PF04377.15 EGO27449.1 - 6.5e-46 156.3 1.0 6.5e-46 156.3 1.0 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGO27449.1 - 9e-26 90.1 6.5 1.9e-25 89.0 6.5 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Sugar_tr PF00083.24 EGO27450.1 - 5.5e-110 368.3 22.6 6.7e-110 368.0 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO27450.1 - 5e-24 84.9 35.7 1.1e-17 64.1 10.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 EGO27450.1 - 2 8.1 6.0 1.2 8.8 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF697) Sec63 PF02889.16 EGO27451.1 - 1.2e-69 234.4 0.0 1.7e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EGO27451.1 - 3.2e-29 102.0 2.3 2.5e-20 73.0 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EGO27451.1 - 4.3e-13 49.6 0.0 3.8e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO27451.1 - 3e-06 27.6 0.0 0.0001 22.6 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.29 EGO27451.1 - 0.00016 22.1 0.3 0.12 12.8 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO27451.1 - 0.0064 16.8 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Glyco_transf_4 PF13439.6 EGO27451.1 - 0.073 13.1 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Adeno_IVa2 PF02456.15 EGO27451.1 - 0.076 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Nsp1_C PF05064.13 EGO27452.1 - 4.5e-30 103.8 0.0 9.4e-30 102.8 0.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EGO27452.1 - 0.0054 17.6 47.5 0.046 14.6 14.6 4.0 1 1 2 3 3 3 3 Nucleoporin FG repeat region FlaC_arch PF05377.11 EGO27452.1 - 0.022 15.1 0.6 0.94 9.9 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 EGO27452.1 - 0.6 10.6 2.8 30 5.2 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1771 PF08590.10 EGO27456.1 - 0.044 14.1 1.1 0.067 13.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_6 PF15288.6 EGO27456.1 - 0.05 13.5 0.9 0.91 9.4 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO27456.1 - 0.057 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO27456.1 - 0.095 12.5 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger DUF4718 PF15842.5 EGO27456.1 - 0.14 12.0 0.5 0.17 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Pribosyltran PF00156.27 EGO27457.1 - 1.9e-14 53.5 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO27457.1 - 0.0051 16.3 0.0 0.0072 15.8 0.0 1.5 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase KCH PF16944.5 EGO27459.1 - 2.8e-90 302.5 16.6 3.4e-90 302.2 16.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3917 PF13055.6 EGO27459.1 - 0.021 15.3 1.0 0.066 13.7 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) Shisa PF13908.6 EGO27459.1 - 2.7 8.2 3.6 33 4.7 0.0 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator NtA PF03146.15 EGO27460.1 - 0.21 11.4 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Agrin NtA domain DUF4651 PF15513.6 EGO27461.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4651) DUF4769 PF15992.5 EGO27462.1 - 0.6 9.9 1.8 0.94 9.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) RINT1_TIP1 PF04437.13 EGO27463.1 - 1.4e-84 284.8 0.0 1.8e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Ribosomal_S14 PF00253.21 EGO27464.1 - 6.5e-22 77.1 0.3 9.1e-22 76.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MFS_1 PF07690.16 EGO27465.1 - 4.7e-21 75.1 53.8 3.2e-14 52.6 20.8 4.2 2 2 1 3 3 3 2 Major Facilitator Superfamily TPPK_C PF12555.8 EGO27465.1 - 1.1 9.3 6.1 19 5.4 0.1 3.9 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Pkinase PF00069.25 EGO27468.1 - 5.3e-72 242.4 0.0 6.7e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27468.1 - 7.4e-29 100.8 0.0 6.6e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO27468.1 - 9.6e-10 38.2 0.1 4.4e-06 26.2 0.0 2.9 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGO27468.1 - 0.0012 17.8 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO27468.1 - 0.042 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO27468.1 - 0.051 13.5 0.0 0.58 10.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Inhibitor_Mig-6 PF11555.8 EGO27468.1 - 0.052 13.6 0.0 0.45 10.6 0.0 2.4 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 HSF_DNA-bind PF00447.17 EGO27469.1 - 3.7e-18 65.9 0.0 6.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding SNARE_assoc PF09335.11 EGO27471.1 - 4.1e-14 53.1 6.3 4.1e-14 53.1 6.3 2.3 1 1 2 3 3 3 1 SNARE associated Golgi protein Cyt_c_ox_IV PF12270.8 EGO27471.1 - 0.57 10.3 2.9 1.9 8.6 0.0 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV RskA PF10099.9 EGO27473.1 - 0.0048 17.2 0.3 0.0054 17.0 0.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF2076 PF09849.9 EGO27473.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF5082 PF16888.5 EGO27473.1 - 0.064 13.5 0.3 0.092 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) MerR-DNA-bind PF09278.11 EGO27473.1 - 0.19 12.3 2.4 0.3 11.7 2.4 1.3 1 0 0 1 1 1 0 MerR, DNA binding PEX11 PF05648.14 EGO27474.1 - 6.8e-12 45.3 1.0 1.3e-05 24.8 0.1 3.0 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) FSIP1 PF15554.6 EGO27474.1 - 0.0038 16.4 0.3 0.0053 15.9 0.3 1.1 1 0 0 1 1 1 1 FSIP1 family Tctex-1 PF03645.13 EGO27475.1 - 7e-12 45.5 0.1 8.7e-12 45.2 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Nop PF01798.18 EGO27480.1 - 5.2e-73 245.3 0.0 7.3e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGO27480.1 - 3e-38 131.4 5.5 3e-38 131.4 5.5 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain WD40 PF00400.32 EGO27482.1 - 5.6e-11 42.8 0.1 1.9e-05 25.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27482.1 - 6.8e-06 26.3 0.0 0.1 12.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Big_6 PF17936.1 EGO27482.1 - 0.0069 16.6 0.2 0.08 13.2 0.0 2.6 3 0 0 3 3 3 1 Bacterial Ig domain PD40 PF07676.12 EGO27482.1 - 0.11 12.4 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Mg_trans_NIPA PF05653.14 EGO27484.1 - 2.8e-58 197.4 8.4 8.7e-55 185.9 4.8 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGO27484.1 - 0.0028 17.8 2.9 0.0028 17.8 2.9 3.2 3 1 0 3 3 3 1 EamA-like transporter family HlyIII PF03006.20 EGO27484.1 - 2.5 7.8 10.8 2.2 8.0 6.5 2.6 2 1 0 2 2 2 0 Haemolysin-III related Pkinase PF00069.25 EGO27485.1 - 5.2e-68 229.3 0.0 1.4e-67 227.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27485.1 - 3.1e-30 105.3 0.0 5.6e-29 101.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO27485.1 - 0.00018 20.9 0.6 0.074 12.3 0.2 2.3 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGO27485.1 - 0.061 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RCDG1 PF15725.5 EGO27485.1 - 0.1 13.0 3.3 5.7 7.4 2.2 2.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Hydrolase_6 PF13344.6 EGO27486.1 - 1.9e-27 95.3 0.0 3.2e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO27486.1 - 8.5e-18 64.2 0.0 1.9e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGO27486.1 - 1.2e-11 45.3 0.0 8.7e-11 42.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO27486.1 - 9.8e-06 25.8 0.0 0.032 14.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.26 EGO27486.1 - 0.014 15.1 0.1 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PGP_phosphatase PF09419.10 EGO27486.1 - 0.018 14.6 0.0 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase AAA_22 PF13401.6 EGO27487.1 - 0.00029 21.1 0.0 1.3 9.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EGO27487.1 - 0.0012 19.3 0.0 0.038 14.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 EGO27487.1 - 0.0048 16.6 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 EGO27487.1 - 0.032 14.6 0.1 7.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 EGO27487.1 - 0.17 11.1 0.0 1 8.5 0.0 2.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) Methyltransf_8 PF05148.15 EGO27488.1 - 9.5e-67 225.0 0.0 2.1e-66 223.9 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGO27488.1 - 3.6e-06 27.5 0.2 1.3e-05 25.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO27488.1 - 0.0001 22.9 0.1 0.00092 19.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO27488.1 - 0.0015 18.3 0.0 1.3 8.8 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGO27488.1 - 0.0073 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO27488.1 - 0.021 15.6 0.0 0.096 13.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGO27488.1 - 0.039 13.9 1.8 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Presenilin PF01080.17 EGO27488.1 - 4.3 6.0 5.3 4.8 5.8 5.3 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EGO27488.1 - 7.2 5.2 9.4 11 4.6 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPRTase PF14681.6 EGO27489.1 - 4.2e-67 225.6 0.0 4.7e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FAD_binding_1 PF00667.20 EGO27490.1 - 1.6e-53 181.6 0.0 2.3e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGO27490.1 - 1.9e-08 34.9 0.0 4.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 EGO27490.1 - 0.0021 18.1 0.0 0.0069 16.5 0.0 1.8 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.24 EGO27490.1 - 0.047 14.0 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.19 EGO27491.1 - 2.2e-115 386.4 12.5 2.5e-115 386.2 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GFO_IDH_MocA PF01408.22 EGO27492.1 - 4.6e-23 82.3 0.0 1e-22 81.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO27492.1 - 6.9e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Lipocalin_7 PF14651.6 EGO27492.1 - 0.043 13.8 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Apt1 PF10351.9 EGO27493.1 - 4e-87 293.1 0.4 6.9e-87 292.3 0.4 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EGO27493.1 - 8.1e-55 186.6 0.0 2.2e-54 185.1 0.0 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EGO27493.1 - 1.8e-37 128.8 0.0 3.7e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EGO27493.1 - 9.1e-25 87.4 0.0 2.1e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EGO27493.1 - 1.4e-21 77.1 0.6 5e-21 75.4 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.16 EGO27494.1 - 2.7e-50 170.7 0.3 4.9e-50 169.8 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Peptidase_M16 PF00675.20 EGO27494.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) DNA_pol_D_N PF18018.1 EGO27494.1 - 0.14 12.3 0.3 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Dpoe2NT PF12213.8 EGO27494.1 - 0.19 12.0 0.1 0.51 10.7 0.1 1.8 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal UPF0183 PF03676.14 EGO27495.1 - 3.9e-63 214.1 0.0 5.3e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Ribosomal_L6e PF01159.19 EGO27497.1 - 3.6e-39 133.7 0.2 5.8e-39 133.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 EGO27497.1 - 3.2e-06 27.3 0.1 3.2e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain 60KD_IMP PF02096.20 EGO27498.1 - 3.7e-15 56.2 0.5 5.2e-13 49.2 0.0 2.1 1 1 1 2 2 2 2 60Kd inner membrane protein DUF2062 PF09835.9 EGO27498.1 - 0.36 10.7 3.0 0.25 11.2 0.2 2.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Clat_adaptor_s PF01217.20 EGO27499.1 - 8.3e-57 191.1 1.7 9.7e-57 190.9 1.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_T PF00929.24 EGO27500.1 - 6.3e-07 30.1 0.0 1.6e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Exonuclease EloA-BP1 PF15870.5 EGO27500.1 - 2.3e-05 24.7 0.1 7.3e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 ElonginA binding-protein 1 CHORD PF04968.12 EGO27500.1 - 0.0053 17.4 2.6 0.0097 16.6 2.6 1.5 1 0 0 1 1 1 1 CHORD TRAM_LAG1_CLN8 PF03798.16 EGO27501.1 - 3.6e-33 115.0 26.9 3.6e-33 115.0 26.9 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EGO27501.1 - 8.4e-20 70.2 1.3 8.4e-20 70.2 1.3 1.8 2 0 0 2 2 2 1 TRAM1-like protein TatC PF00902.18 EGO27501.1 - 0.11 12.3 6.0 0.16 11.7 4.5 2.1 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Histone PF00125.24 EGO27502.1 - 1.4e-42 145.1 0.6 1.6e-42 145.0 0.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGO27502.1 - 0.0004 20.5 0.1 0.00061 19.9 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGO27502.1 - 0.0007 19.9 0.1 0.00097 19.5 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO27502.1 - 0.002 18.3 0.9 0.0073 16.6 0.2 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGO27502.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MAP7 PF05672.11 EGO27503.1 - 0.24 11.1 37.5 0.53 10.0 37.5 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family AAA_11 PF13086.6 EGO27503.1 - 0.6 9.8 6.8 1.2 8.8 6.8 1.5 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 EGO27503.1 - 8 4.8 11.1 11 4.3 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3987 PF13148.6 EGO27503.1 - 8.8 5.2 11.9 13 4.6 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TF_Zn_Ribbon PF08271.12 EGO27504.1 - 0.16 11.5 0.0 0.46 10.0 0.0 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RRN7 PF11781.8 EGO27504.1 - 0.18 11.5 0.1 0.43 10.3 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DnaJ PF00226.31 EGO27505.1 - 1.7e-14 53.7 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Gln-synt_C PF00120.24 EGO27506.1 - 1.4e-15 57.2 0.0 2e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGO27506.1 - 1.1e-11 44.3 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Iso_dh PF00180.20 EGO27507.1 - 1.2e-78 264.7 0.0 1.5e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Hydrolase_4 PF12146.8 EGO27508.1 - 0.092 12.0 0.0 4.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Piwi PF02171.17 EGO27509.1 - 1.8e-89 300.0 0.0 2.3e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EGO27509.1 - 8.8e-17 60.5 0.1 2.3e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EGO27509.1 - 2.6e-16 59.6 0.1 6.5e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EGO27509.1 - 3.8e-11 43.1 0.0 9.3e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EGO27509.1 - 1.1e-08 34.9 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1640 PF07798.11 EGO27509.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TspO_MBR PF03073.15 EGO27510.1 - 7.8e-41 139.3 9.9 9.1e-41 139.1 9.9 1.0 1 0 0 1 1 1 1 TspO/MBR family Ipi1_N PF12333.8 EGO27511.1 - 3.8e-23 82.0 0.4 1e-19 71.0 0.0 4.0 3 1 1 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation DUF531 PF04407.12 EGO27512.1 - 0.035 14.2 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF531) TSC22 PF01166.18 EGO27513.1 - 0.056 13.8 0.3 0.19 12.0 0.3 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4218 PF13960.6 EGO27514.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Polysacc_deac_1 PF01522.21 EGO27515.1 - 5.2e-21 74.8 0.0 9.6e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HLH PF00010.26 EGO27516.1 - 1.8e-13 50.2 0.1 3.7e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.29 EGO27518.1 - 7.5e-07 29.6 0.0 8.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGO27518.1 - 1.7e-05 24.9 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGO27518.1 - 0.00019 21.8 0.0 0.00022 21.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGO27518.1 - 0.0046 16.7 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGO27518.1 - 0.0079 15.4 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EGO27518.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EGO27518.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EGO27518.1 - 0.012 15.5 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGO27518.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EGO27518.1 - 0.021 15.3 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO27518.1 - 0.028 14.6 0.0 0.036 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO27518.1 - 0.039 14.1 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGO27518.1 - 0.039 14.4 0.0 0.062 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO27518.1 - 0.044 14.2 0.0 0.055 13.9 0.0 1.3 1 1 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 EGO27518.1 - 0.056 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 EGO27518.1 - 0.057 13.3 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 NTPase DUF815 PF05673.13 EGO27518.1 - 0.065 12.4 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGO27518.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EGO27518.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase AAA_22 PF13401.6 EGO27518.1 - 0.16 12.2 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGO27518.1 - 0.17 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO27518.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region Cupin_8 PF13621.6 EGO27519.1 - 4.5e-62 210.1 0.0 5.6e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGO27519.1 - 0.00048 19.7 0.2 0.00082 18.9 0.2 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGO27519.1 - 0.0031 17.9 0.1 0.0096 16.3 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGO27519.1 - 0.012 15.4 0.1 0.093 12.5 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Ribosomal_L7Ae PF01248.26 EGO27520.1 - 4.5e-25 87.2 0.7 7.9e-25 86.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RFX_DNA_binding PF02257.15 EGO27521.1 - 1.2e-27 96.4 0.0 3.4e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain NuDC PF16273.5 EGO27521.1 - 0.015 15.8 2.1 0.029 14.9 2.1 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain DHC_N2 PF08393.13 EGO27521.1 - 0.086 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Metallophos PF00149.28 EGO27522.1 - 5.3e-07 30.3 0.1 9.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.28 EGO27524.1 - 2.8e-37 128.3 0.0 3.9e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGO27524.1 - 2.3e-07 30.6 1.2 4.1e-07 29.8 1.2 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGO27524.1 - 0.0038 18.2 0.0 0.0087 17.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4199 PF13858.6 EGO27525.1 - 8.3 6.8 8.5 5.4 7.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF5592 PF17332.2 EGO27526.1 - 2.5 8.7 6.3 2 9.0 2.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5592) EamA PF00892.20 EGO27527.1 - 0.00044 20.4 1.1 0.00052 20.2 1.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family PalH PF08733.10 EGO27527.1 - 0.046 12.7 0.9 0.052 12.6 0.9 1.0 1 0 0 1 1 1 0 PalH/RIM21 Holin_9 PF16936.5 EGO27527.1 - 0.12 12.5 2.2 0.23 11.7 2.2 1.6 1 1 0 1 1 1 0 Putative holin UQ_con PF00179.26 EGO27528.1 - 7.3e-37 126.1 0.3 8.3e-37 125.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FmiP_Thoc5 PF09766.9 EGO27529.1 - 9.4e-37 127.1 9.3 1.1e-36 126.9 9.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 T3SSipB PF16535.5 EGO27529.1 - 0.00085 19.8 5.7 0.01 16.3 0.9 2.2 2 0 0 2 2 2 1 Type III cell invasion protein SipB Pdase_C33_assoc PF14756.6 EGO27529.1 - 0.0031 17.5 0.2 1.1 9.2 0.1 2.1 2 0 0 2 2 2 2 Peptidase_C33-associated domain Syntaxin PF00804.25 EGO27529.1 - 0.0041 16.8 6.3 0.031 14.0 0.6 2.2 2 0 0 2 2 2 2 Syntaxin SKA2 PF16740.5 EGO27529.1 - 0.019 14.8 8.9 0.57 10.0 2.9 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 CREPT PF16566.5 EGO27529.1 - 0.035 14.3 5.1 0.13 12.5 1.1 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Mod_r PF07200.13 EGO27529.1 - 0.048 13.8 11.4 0.05 13.7 4.7 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Mustang PF15682.5 EGO27529.1 - 0.13 12.3 0.6 0.24 11.5 0.6 1.3 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 DUF3450 PF11932.8 EGO27529.1 - 0.19 11.0 6.2 0.9 8.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 EGO27529.1 - 0.64 10.3 3.1 5.5 7.3 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EGO27529.1 - 0.69 9.2 6.5 1.1 8.5 6.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 EGO27529.1 - 1.5 8.5 3.5 22 4.7 1.4 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Muted PF14942.6 EGO27529.1 - 3.6 7.9 9.8 4.1 7.7 1.9 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein G6PD_C PF02781.16 EGO27530.1 - 6.8e-111 370.1 0.0 9.4e-111 369.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGO27530.1 - 3.1e-59 200.6 0.0 4.7e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DIE2_ALG10 PF04922.12 EGO27531.1 - 2e-124 415.9 13.0 2.4e-124 415.6 13.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Rpr2 PF04032.16 EGO27533.1 - 0.0047 17.2 0.8 0.0047 17.2 0.8 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.6 EGO27533.1 - 0.039 13.7 1.0 0.88 9.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Churchill PF06573.11 EGO27533.1 - 0.11 12.8 0.4 0.22 11.9 0.4 1.4 1 0 0 1 1 1 0 Churchill protein DUF4674 PF15719.5 EGO27533.1 - 0.27 11.3 6.8 1.4 9.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) RNB PF00773.19 EGO27535.1 - 1.1e-97 327.3 0.2 1.1e-97 327.3 0.2 1.8 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 EGO27535.1 - 3.5e-25 88.1 0.3 3.5e-25 88.1 0.3 1.9 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EGO27535.1 - 5.7e-25 87.2 0.0 1.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EGO27535.1 - 0.00013 22.0 0.0 0.063 13.5 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 EGO27535.1 - 0.00098 19.0 0.8 0.0029 17.5 0.0 2.3 2 1 0 2 2 2 1 S1 domain T2SSF PF00482.23 EGO27535.1 - 0.0042 17.0 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Rrp44_CSD1 PF17216.3 EGO27535.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain BAF1_ABF1 PF04684.13 EGO27535.1 - 0.027 13.6 4.2 0.53 9.3 0.5 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Iso_dh PF00180.20 EGO27536.1 - 2.1e-101 339.6 0.0 2.6e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Snf7 PF03357.21 EGO27537.1 - 3.4e-27 95.2 20.1 7.7e-27 94.0 20.1 1.6 1 1 0 1 1 1 1 Snf7 LUC7 PF03194.15 EGO27537.1 - 0.4 10.3 9.4 0.83 9.3 9.5 1.7 1 1 0 1 1 1 0 LUC7 N_terminus T3SS_needle_E PF08988.10 EGO27537.1 - 1.1 9.5 5.8 0.76 10.0 0.5 3.2 3 1 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle YlqD PF11068.8 EGO27537.1 - 5.3 7.4 15.6 0.24 11.8 6.9 2.6 1 1 1 2 2 2 0 YlqD protein GPI-anchored PF10342.9 EGO27538.1 - 3.5e-10 40.5 0.1 8.1e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MCRA PF06100.11 EGO27538.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family Fungal_trans PF04082.18 EGO27539.1 - 3.5e-19 68.9 0.1 6.3e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM70 PF14967.6 EGO27539.1 - 0.5 9.8 2.1 1.1 8.7 2.1 1.5 1 0 0 1 1 1 0 FAM70 protein Med17 PF10156.9 EGO27540.1 - 1.1e-44 153.0 0.0 1.3e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ribosomal_L5e PF17144.4 EGO27541.1 - 6e-82 273.5 0.1 9.3e-82 272.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGO27541.1 - 4.2e-34 117.4 1.8 4.2e-34 117.4 1.8 2.0 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region RRM_1 PF00076.22 EGO27542.1 - 4.1e-15 55.4 0.1 5.9e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.11 EGO27543.1 - 4.3e-34 116.8 0.0 1.9e-33 114.7 0.0 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Exo70 PF03081.15 EGO27543.1 - 0.0092 15.1 2.3 0.019 14.0 0.5 2.3 2 1 0 2 2 2 1 Exo70 exocyst complex subunit Arm PF00514.23 EGO27543.1 - 0.014 15.4 0.4 0.095 12.8 0.1 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PPP1R26_N PF15740.5 EGO27543.1 - 0.016 13.9 0.2 0.026 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus CLASP_N PF12348.8 EGO27543.1 - 0.025 14.2 0.1 0.063 12.8 0.1 1.6 1 0 0 1 1 1 0 CLASP N terminal Host_attach PF10116.9 EGO27543.1 - 0.039 14.5 0.4 0.47 11.0 0.0 2.8 2 0 0 2 2 2 0 Protein required for attachment to host cells baeRF_family12 PF18856.1 EGO27543.1 - 0.42 11.2 0.0 0.42 11.2 0.0 2.8 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 12 ANAPC4_WD40 PF12894.7 EGO27544.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO27544.1 - 0.032 15.1 0.4 2.2 9.3 0.1 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF5122 PF17164.4 EGO27544.1 - 0.084 13.2 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller Thioredoxin PF00085.20 EGO27545.1 - 2.6e-57 191.2 0.0 1.3e-31 108.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGO27545.1 - 8.8e-42 143.1 0.0 3.8e-34 118.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGO27545.1 - 7.9e-07 29.2 0.0 0.046 13.9 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGO27545.1 - 2.7e-06 27.8 0.1 0.017 15.6 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGO27545.1 - 1.7e-05 25.0 0.0 0.032 14.6 0.0 3.6 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 EGO27545.1 - 0.0001 22.2 0.1 0.068 13.1 0.0 3.3 3 0 0 3 3 3 1 AhpC/TSA family Calsequestrin PF01216.17 EGO27545.1 - 0.0014 17.7 0.0 0.0032 16.5 0.0 1.6 1 1 1 2 2 2 1 Calsequestrin OST3_OST6 PF04756.13 EGO27545.1 - 0.0028 17.1 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGO27545.1 - 0.022 14.5 0.3 2.1 8.0 0.1 3.0 3 0 0 3 3 3 0 Redoxin FAT PF02259.23 EGO27547.1 - 3e-69 233.9 7.3 7.3e-69 232.6 7.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGO27547.1 - 1.1e-24 87.7 0.0 7.9e-24 84.8 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Imm2 PF14426.6 EGO27547.1 - 0.099 12.7 0.0 0.57 10.3 0.0 2.3 1 0 0 1 1 1 0 Immunity protein Imm2 FATC PF02260.20 EGO27547.1 - 0.11 12.3 0.4 0.64 9.9 0.1 2.6 3 0 0 3 3 3 0 FATC domain TPR_14 PF13428.6 EGO27547.1 - 0.93 10.5 3.4 11 7.2 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Sorting_nexin PF03700.13 EGO27547.1 - 1.1 9.9 2.9 2.2 8.8 2.9 1.5 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Bromodomain PF00439.25 EGO27548.1 - 2.8e-23 81.8 0.2 4.8e-23 81.0 0.2 1.4 1 0 0 1 1 1 1 Bromodomain PAXX PF15384.6 EGO27548.1 - 0.068 12.8 1.5 0.11 12.2 1.5 1.4 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Asp PF00026.23 EGO27549.1 - 1.1e-111 373.3 0.2 1.3e-111 373.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO27549.1 - 1.2e-13 51.7 3.7 2.1e-08 34.6 0.6 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO27549.1 - 1.3e-05 25.8 0.1 0.041 14.5 0.0 3.0 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EGO27549.1 - 9.6e-05 22.9 0.0 0.084 13.4 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGO27549.1 - 0.0002 21.1 0.0 0.0053 16.5 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal WD40 PF00400.32 EGO27550.1 - 1e-18 67.3 3.2 6e-07 30.1 0.3 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27550.1 - 0.0011 19.2 0.1 0.023 15.0 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2722 PF10846.8 EGO27550.1 - 0.042 12.8 1.8 0.067 12.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.12 EGO27550.1 - 0.26 10.6 10.4 0.45 9.8 10.4 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EGO27550.1 - 0.33 10.5 6.5 0.65 9.5 6.5 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EGO27550.1 - 0.45 10.2 6.9 0.65 9.7 6.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 EGO27550.1 - 0.71 9.6 4.4 1.2 8.9 4.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YL1 PF05764.13 EGO27550.1 - 1 9.5 6.0 1.6 8.8 6.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PCI PF01399.27 EGO27551.1 - 1.9e-10 41.2 0.0 9.8e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EGO27551.1 - 0.0065 16.2 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TAFH PF07531.14 EGO27551.1 - 0.03 14.4 0.5 4.9 7.3 0.0 3.1 3 0 0 3 3 3 0 NHR1 homology to TAF TPR_14 PF13428.6 EGO27551.1 - 0.12 13.3 0.4 64 4.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3336 PF11815.8 EGO27553.1 - 9.1e-52 174.4 3.8 1.3e-51 173.9 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGO27553.1 - 2.8e-18 66.9 0.1 6.9e-18 65.6 0.1 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3759 PF12585.8 EGO27554.1 - 6.3e-38 128.7 8.4 7.4e-38 128.5 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) TetR_C_31 PF17940.1 EGO27554.1 - 0.0017 18.6 0.2 0.0019 18.4 0.2 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF2894 PF11445.8 EGO27554.1 - 0.037 14.5 1.7 0.047 14.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF3759 PF12585.8 EGO27555.1 - 3e-37 126.5 10.5 3.7e-37 126.2 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ORC4_C PF14629.6 EGO27556.1 - 2.7e-26 92.3 0.3 4.7e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EGO27556.1 - 5.6e-10 39.9 3.3 2.9e-09 37.5 3.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EGO27556.1 - 0.034 14.6 0.2 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Med20 PF08612.11 EGO27557.1 - 6e-09 35.6 0.0 0.00068 19.1 0.0 2.1 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BCDHK_Adom3 PF10436.9 EGO27558.1 - 3.2e-37 127.9 0.0 4.5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGO27558.1 - 4.5e-08 33.6 0.0 2e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGO27558.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 EGO27561.1 - 8e-65 218.8 0.1 2.2e-43 148.6 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27561.1 - 3.4e-28 98.6 0.2 6.2e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO27561.1 - 1.2e-06 27.8 0.1 1.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO27561.1 - 0.00018 20.9 0.6 0.00076 18.9 0.0 2.1 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO27561.1 - 0.00059 19.8 0.2 0.016 15.1 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO27561.1 - 0.0054 16.1 0.3 0.016 14.5 0.1 1.9 2 1 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 EGO27561.1 - 0.019 13.9 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGO27561.1 - 0.036 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EGO27561.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGO27561.1 - 0.047 12.5 0.1 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_C PF00433.24 EGO27561.1 - 0.056 14.2 0.1 0.12 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain DEAD PF00270.29 EGO27562.1 - 6.8e-21 74.8 0.2 8e-21 74.6 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO27562.1 - 0.00023 21.2 0.0 0.00027 21.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EGO27562.1 - 0.0052 16.3 0.1 0.0057 16.2 0.1 1.0 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SBF_like PF13593.6 EGO27562.1 - 0.006 15.9 0.1 0.0065 15.8 0.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SWI2_SNF2 PF18766.1 EGO27562.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 EGO27562.1 - 0.072 13.4 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4217 PF13959.6 EGO27563.1 - 1e-24 86.5 0.2 1.7e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Pox_RNA_Pol_19 PF05320.12 EGO27563.1 - 0.027 14.5 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HTH_30 PF13556.6 EGO27563.1 - 0.053 13.3 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF3818 PF12825.7 EGO27564.1 - 1e-131 439.0 0.3 1.5e-131 438.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGO27564.1 - 3.5e-32 111.1 0.4 8.5e-32 109.9 0.4 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EGO27564.1 - 6.6e-10 39.0 0.2 6.2e-09 35.8 0.0 2.7 2 1 0 2 2 2 1 PX domain Hormone_1 PF00103.20 EGO27564.1 - 0.077 12.7 0.1 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 Somatotropin hormone family DUF1682 PF07946.14 EGO27566.1 - 2.3e-106 355.7 1.1 2.6e-106 355.5 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Tim17 PF02466.19 EGO27569.1 - 1.1e-08 35.4 13.2 1.6e-08 34.9 13.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EGO27569.1 - 0.28 11.3 17.8 0.41 10.8 6.7 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5518) LON_substr_bdg PF02190.16 EGO27570.1 - 1.4e-17 64.3 0.0 2.8e-17 63.3 0.0 1.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EGO27570.1 - 5.3e-10 39.0 13.1 5.3e-10 39.0 13.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO27570.1 - 3.6e-08 33.3 25.9 5.5e-07 29.5 10.9 2.9 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO27570.1 - 1.1e-07 31.8 25.8 0.00068 19.7 13.3 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGO27570.1 - 1.2e-07 31.6 25.6 5.3e-06 26.3 11.3 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO27570.1 - 1.5e-07 31.1 26.0 1.9e-07 30.8 11.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO27570.1 - 4.2e-07 29.7 19.9 1.2e-06 28.3 6.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO27570.1 - 1.3e-06 28.6 11.9 1.3e-06 28.6 11.9 2.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EGO27570.1 - 0.0001 22.1 8.9 0.0001 22.1 8.9 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGO27570.1 - 0.0013 18.8 3.2 0.0013 18.8 3.2 2.6 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-P11 PF03854.14 EGO27570.1 - 0.012 15.2 6.7 0.012 15.2 6.7 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 EGO27570.1 - 0.014 15.1 2.8 0.014 15.1 2.8 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGO27570.1 - 0.019 15.3 8.1 0.019 15.3 8.1 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain U-box PF04564.15 EGO27570.1 - 0.15 12.2 1.1 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 U-box domain zf-RING_6 PF14835.6 EGO27570.1 - 2.7 7.9 11.3 0.12 12.3 1.7 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein RTA1 PF04479.13 EGO27571.1 - 9.5e-54 182.1 5.5 1.7e-53 181.3 5.5 1.4 1 0 0 1 1 1 1 RTA1 like protein TMEM40 PF15817.5 EGO27571.1 - 4 7.2 9.1 0.95 9.2 1.4 2.6 3 0 0 3 3 3 0 Transmembrane protein 40 family VID27 PF08553.10 EGO27573.1 - 6.1e-173 574.9 1.8 8e-173 574.5 1.8 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EGO27573.1 - 9.1e-58 194.9 0.2 9.1e-58 194.9 0.2 2.9 4 0 0 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 EGO27573.1 - 2.2e-31 108.3 0.2 7.1e-31 106.7 0.2 2.0 1 0 0 1 1 1 1 VID27 PH-like domain BUD22 PF09073.10 EGO27573.1 - 9.3 5.5 12.9 3.1 7.1 4.5 2.2 2 0 0 2 2 2 0 BUD22 Phage_holin_1 PF04531.13 EGO27574.1 - 8.9 6.9 6.4 1.2e+02 3.3 0.5 3.2 3 0 0 3 3 3 0 Bacteriophage holin CRCB PF02537.15 EGO27576.1 - 4.8e-32 110.1 18.2 1.3e-19 70.3 5.6 2.4 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Ribosomal_L36e PF01158.18 EGO27577.1 - 3e-40 136.4 2.5 3.3e-40 136.2 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EGO27577.1 - 0.024 14.5 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold SNARE_assoc PF09335.11 EGO27578.1 - 2.9e-17 63.3 4.0 5.5e-17 62.4 4.0 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein Mito_carr PF00153.27 EGO27579.1 - 2.5e-61 203.6 4.6 1.9e-22 78.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EGO27579.1 - 0.00058 19.2 0.0 0.037 13.6 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGO27579.1 - 0.014 15.9 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EGO27579.1 - 0.014 15.3 0.0 0.23 11.5 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 EGO27579.1 - 0.031 13.8 0.8 0.065 12.8 0.1 1.9 2 0 0 2 2 2 0 EF hand Amidohydro_2 PF04909.14 EGO27580.1 - 2.8e-28 99.6 0.1 3.4e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.25 EGO27581.1 - 3.1e-41 141.0 0.0 3.8e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO27581.1 - 3.3e-35 121.7 0.0 4e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO27581.1 - 1.1e-17 64.5 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO27581.1 - 0.00012 22.0 0.1 0.00026 20.9 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO27581.1 - 0.00015 21.3 0.1 0.00045 19.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGO27581.1 - 0.011 16.0 0.1 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain YjeF_N PF03853.15 EGO27581.1 - 0.034 14.0 0.1 0.19 11.6 0.0 2.1 2 1 0 2 2 2 0 YjeF-related protein N-terminus 3Beta_HSD PF01073.19 EGO27581.1 - 0.04 12.9 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGO27581.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Minor_capsid_3 PF12691.7 EGO27581.1 - 0.17 12.3 0.0 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage Sec23_trunk PF04811.15 EGO27581.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Transket_pyr PF02779.24 EGO27582.1 - 2e-46 157.9 0.0 3.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGO27582.1 - 2.5e-40 137.2 0.1 4.6e-40 136.4 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGO27582.1 - 0.071 13.4 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II Histidinol_dh PF00815.20 EGO27583.1 - 2.1e-164 547.4 0.8 2.8e-164 547.0 0.8 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EGO27583.1 - 8.2e-25 86.4 0.1 1.9e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EGO27583.1 - 1.4e-11 44.6 0.4 4.7e-11 43.0 0.3 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase FAD_binding_9 PF08021.11 EGO27583.1 - 0.045 14.0 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain MazG-like PF12643.7 EGO27583.1 - 0.049 13.9 0.6 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 MazG-like family HNF-1A_C PF04813.12 EGO27583.1 - 0.31 11.8 4.8 0.16 12.7 1.5 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Snf7 PF03357.21 EGO27585.1 - 8.5e-33 113.4 25.2 1.2e-32 112.9 25.2 1.3 1 1 0 1 1 1 1 Snf7 SPOB_a PF14689.6 EGO27585.1 - 0.032 14.0 2.3 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain FliL PF03748.14 EGO27585.1 - 1.6 9.4 12.0 0.26 11.9 3.6 2.7 1 1 0 2 2 2 0 Flagellar basal body-associated protein FliL DUF1690 PF07956.11 EGO27585.1 - 1.8 9.0 16.4 1.5 9.2 8.4 2.3 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Atg14 PF10186.9 EGO27585.1 - 4 6.4 12.2 35 3.3 12.2 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_60s PF00428.19 EGO27585.1 - 6.2 7.5 10.9 2 9.1 1.3 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein TRAM_LAG1_CLN8 PF03798.16 EGO27586.1 - 3.7e-47 160.6 24.8 5.8e-47 160.0 24.8 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EGO27586.1 - 2.9e-08 33.3 0.2 2.9e-08 33.3 0.2 2.1 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.22 EGO27587.1 - 2.1e-16 59.5 0.0 5.1e-07 29.4 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.8 EGO27587.1 - 0.0006 18.7 1.8 0.00085 18.2 1.8 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RRM_occluded PF16842.5 EGO27587.1 - 0.0028 17.5 0.0 0.046 13.6 0.0 2.4 2 1 0 2 2 2 1 Occluded RNA-recognition motif GEMIN8 PF15348.6 EGO27587.1 - 0.014 15.7 1.7 0.021 15.2 1.7 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 RRN3 PF05327.11 EGO27587.1 - 0.026 13.1 0.6 0.025 13.2 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Radial_spoke PF04712.12 EGO27587.1 - 0.037 13.0 2.8 0.055 12.4 2.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein RRM_5 PF13893.6 EGO27587.1 - 0.041 13.5 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.13 EGO27587.1 - 0.39 8.8 8.3 0.51 8.4 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGO27587.1 - 2.9 7.1 7.4 3.8 6.8 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein DJ-1_PfpI PF01965.24 EGO27588.1 - 2.8e-12 46.7 0.0 5.8e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGO27588.1 - 0.00071 19.3 0.0 0.049 13.3 0.0 2.1 1 1 1 2 2 2 2 ThiJ/PfpI family-like Mob1_phocein PF03637.17 EGO27589.1 - 3.1e-79 264.9 0.0 3.6e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.29 EGO27591.1 - 4.3e-44 150.4 0.0 7.5e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO27591.1 - 4.5e-25 88.1 0.0 1.2e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO27591.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGO27591.1 - 0.099 12.9 0.0 0.38 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.19 EGO27592.1 - 3.8e-13 49.6 0.4 6.8e-13 48.8 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Sua5_yciO_yrdC PF01300.18 EGO27593.1 - 1.3e-49 168.1 0.0 2.8e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGO27593.1 - 2.4e-29 102.6 0.0 3.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Complex1_LYR_2 PF13233.6 EGO27594.1 - 6.4e-16 58.9 0.1 8.3e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like FadR_C PF07840.12 EGO27594.1 - 0.045 13.6 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 FadR C-terminal domain RRM_1 PF00076.22 EGO27595.1 - 3e-09 36.6 0.0 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EGO27595.1 - 0.0049 16.8 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DEAD PF00270.29 EGO27596.1 - 6.4e-17 61.9 0.0 1.1e-16 61.1 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO27596.1 - 4e-08 33.6 0.0 9.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 EGO27597.1 - 4.5e-41 138.1 22.8 3.6e-05 24.4 0.5 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27597.1 - 1.7e-13 50.7 3.1 0.28 11.5 0.0 7.3 5 1 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO27597.1 - 4.3e-05 22.6 0.0 2.1 7.3 0.0 4.7 2 1 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein GCV_T PF01571.21 EGO27598.1 - 1.8e-06 27.5 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GST_N PF02798.20 EGO27599.1 - 1.1e-12 48.1 0.1 2.6e-12 46.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO27599.1 - 4.6e-11 42.8 0.0 1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO27599.1 - 2.1e-08 34.3 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO27599.1 - 5e-08 33.2 0.0 8.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO27599.1 - 5.8e-06 26.2 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO27599.1 - 6.3e-06 26.3 0.0 1.6e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF1640 PF07798.11 EGO27600.1 - 1.1e-42 146.1 10.2 1.3e-42 145.8 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 EGO27600.1 - 0.084 12.4 5.3 0.14 11.7 4.8 1.5 1 1 0 1 1 1 0 fzo-like conserved region DUF1664 PF07889.12 EGO27600.1 - 0.26 11.3 3.7 0.46 10.5 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SPX PF03105.19 EGO27600.1 - 0.36 10.7 5.2 0.47 10.3 5.2 1.2 1 0 0 1 1 1 0 SPX domain Mago-bind PF09282.10 EGO27601.1 - 1.1e-14 54.0 2.6 2.1e-14 53.1 2.6 1.5 1 0 0 1 1 1 1 Mago binding Pox_Ag35 PF03286.14 EGO27601.1 - 0.002 18.0 7.7 0.0025 17.6 7.7 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PBP1_TM PF14812.6 EGO27601.1 - 0.32 11.4 6.3 0.59 10.5 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 EGO27601.1 - 2 7.6 4.5 2.4 7.3 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 EGO27601.1 - 2.2 7.9 6.1 3.2 7.4 6.1 1.3 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.13 EGO27601.1 - 8.8 5.0 6.6 9.6 4.9 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ATP_bind_1 PF03029.17 EGO27602.1 - 3e-75 253.1 0.0 4e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArsA_ATPase PF02374.15 EGO27602.1 - 0.0041 16.3 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_16 PF13191.6 EGO27602.1 - 0.0053 17.2 0.0 0.039 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGO27602.1 - 0.0082 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF463 PF04317.12 EGO27602.1 - 0.009 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 YcjX-like family, DUF463 MeaB PF03308.16 EGO27602.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EGO27602.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EGO27602.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EGO27602.1 - 0.031 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO27602.1 - 0.035 13.8 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EGO27602.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGO27602.1 - 0.048 13.7 0.0 0.074 13.1 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 EGO27602.1 - 0.056 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 EGO27602.1 - 0.063 13.1 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EGO27602.1 - 0.068 13.7 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGO27602.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EGO27602.1 - 0.093 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 EGO27602.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 EGO27602.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EGO27602.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGO27602.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGO27602.1 - 0.15 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EGO27602.1 - 0.19 11.6 0.1 0.66 9.9 0.0 1.9 2 1 1 3 3 3 0 NTPase KTI12 PF08433.10 EGO27602.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 EGO27602.1 - 0.22 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.16 EGO27602.1 - 0.23 10.9 0.0 0.9 8.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EGO27602.1 - 0.25 11.0 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ssu72 PF04722.13 EGO27604.1 - 7.5e-85 283.3 0.0 9.4e-85 283.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein EF-hand_7 PF13499.6 EGO27606.1 - 1e-26 93.1 5.7 2.4e-17 63.1 1.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGO27606.1 - 4.8e-24 82.1 12.3 9.9e-08 31.0 0.2 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EGO27606.1 - 4.5e-21 72.9 8.4 1.6e-06 27.5 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGO27606.1 - 1.7e-12 46.3 7.4 0.00077 18.8 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGO27606.1 - 1.3e-10 41.0 10.0 8.3e-05 22.4 0.8 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGO27606.1 - 5.5e-08 32.7 4.7 0.011 15.7 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGO27606.1 - 0.00047 20.5 3.7 0.24 11.7 0.6 3.7 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGO27606.1 - 0.013 15.8 1.7 2.3 8.6 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.13 EGO27606.1 - 0.08 12.9 2.5 7.7 6.4 0.0 3.1 2 1 0 3 3 3 0 Caleosin related protein Pan3_PK PF18101.1 EGO27606.1 - 0.16 11.9 1.0 0.2 11.6 0.2 1.6 2 0 0 2 2 2 0 Pan3 Pseudokinase domain Brix PF04427.18 EGO27607.1 - 7.6e-32 111.0 0.2 1.1e-31 110.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain Ribonuc_red_sm PF00268.21 EGO27608.1 - 5e-123 410.0 0.5 6.3e-123 409.7 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EGO27608.1 - 0.12 13.2 0.3 0.31 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Fungal_trans PF04082.18 EGO27609.1 - 3e-25 88.7 0.2 6.1e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO27609.1 - 1.4e-05 25.1 11.1 2.7e-05 24.2 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YppG PF14179.6 EGO27612.1 - 2.9 8.6 5.1 3 8.6 4.2 1.5 1 1 1 2 2 2 0 YppG-like protein Pkinase PF00069.25 EGO27613.1 - 0.00018 21.0 0.1 0.018 14.4 0.2 2.7 2 1 0 3 3 3 2 Protein kinase domain LNS2 PF08235.13 EGO27614.1 - 2.3e-100 334.7 0.0 3.2e-100 334.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGO27614.1 - 1.3e-35 121.5 0.0 3.7e-35 120.0 0.0 1.9 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EGO27614.1 - 0.00076 19.6 0.0 0.0023 18.0 0.0 1.8 1 1 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 EGO27614.1 - 0.087 12.4 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.15 EGO27615.1 - 1.5e-09 37.7 0.5 2.3e-09 37.2 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) tRNA-synt_1 PF00133.22 EGO27615.1 - 0.18 10.0 0.0 0.19 10.0 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) RRN3 PF05327.11 EGO27616.1 - 1e-199 664.7 0.0 1e-199 664.7 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 EGO27616.1 - 2.1 7.9 10.1 8.8 5.9 5.2 2.7 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting RicinB_lectin_2 PF14200.6 EGO27620.1 - 6.5e-08 33.2 1.0 3.6e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like RbsD_FucU PF05025.13 EGO27621.1 - 0.022 15.2 0.5 0.041 14.3 0.5 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family IU_nuc_hydro PF01156.19 EGO27625.1 - 5e-85 285.8 0.1 5.9e-85 285.5 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MCM PF00493.23 EGO27626.1 - 3.2e-103 343.7 0.4 4.8e-103 343.1 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO27626.1 - 1e-38 132.0 0.1 1.9e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EGO27626.1 - 2.6e-29 101.6 1.6 5.3e-29 100.6 1.6 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 EGO27626.1 - 7.5e-26 90.7 1.2 2.6e-25 89.0 1.2 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 EGO27626.1 - 1.3e-24 86.4 2.5 1.5e-24 86.2 1.0 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGO27626.1 - 1.1e-07 31.5 0.0 1.3e-06 27.9 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGO27626.1 - 0.0021 17.9 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO27626.1 - 0.0025 17.6 0.0 0.0062 16.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EGO27626.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Y_phosphatase3 PF13350.6 EGO27627.1 - 1.2e-64 218.5 0.0 1.4e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO27627.1 - 0.00047 19.8 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO27627.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO27627.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Vac14_Fig4_bd PF11916.8 EGO27628.1 - 2.7e-79 265.0 7.7 4.8e-79 264.2 7.7 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGO27628.1 - 1.5e-41 140.9 0.2 4.1e-36 123.5 0.0 3.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGO27628.1 - 4.9e-10 38.8 0.5 0.013 15.7 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EGO27628.1 - 2.5e-05 24.5 0.2 1.5 9.3 0.1 4.4 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EGO27628.1 - 4.5e-05 23.5 6.6 0.33 11.0 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGO27628.1 - 0.00011 22.6 0.1 6.7 7.3 0.0 5.9 4 2 2 6 6 6 1 HEAT-like repeat ParcG PF10274.9 EGO27628.1 - 0.0027 17.8 1.1 2.9 8.0 0.2 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein DNA_pol3_gamma3 PF12169.8 EGO27628.1 - 0.098 12.6 1.5 0.48 10.3 0.1 2.7 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III Arm PF00514.23 EGO27628.1 - 0.13 12.3 1.2 86 3.4 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RWD PF05773.22 EGO27629.1 - 1.5e-16 60.7 0.7 2.8e-16 59.8 0.7 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 EGO27629.1 - 1.6e-16 60.3 40.3 7.3e-11 42.1 6.0 4.3 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGO27629.1 - 4.3e-05 23.5 7.3 4.3e-05 23.5 7.3 4.0 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGO27629.1 - 0.00011 22.5 9.2 0.00011 22.5 9.2 5.1 4 1 1 5 5 5 2 Ring finger domain zf-RING_5 PF14634.6 EGO27629.1 - 0.0011 18.9 7.4 0.0011 18.9 7.4 4.4 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO27629.1 - 0.0096 15.8 5.2 0.0096 15.8 5.2 5.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO27629.1 - 0.29 11.0 44.2 0.03 14.1 7.0 5.9 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO27629.1 - 4.6 7.1 14.8 0.049 13.4 6.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger Glyco_hydro_3_C PF01915.22 EGO27630.1 - 4.4e-63 212.9 0.0 1.6e-62 211.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO27630.1 - 3.7e-43 148.1 0.0 6.9e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO27630.1 - 1.9e-26 92.0 0.2 2e-25 88.7 0.1 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EGO27630.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 PA14 domain FAD_binding_4 PF01565.23 EGO27630.1 - 0.033 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain RNF220 PF15926.5 EGO27631.1 - 8.2e-22 78.0 15.0 8.2e-22 78.0 15.0 2.7 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 EGO27631.1 - 2.3e-09 37.0 23.1 6.2e-09 35.6 14.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO27631.1 - 2.7e-06 27.1 19.5 9e-05 22.3 12.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO27631.1 - 2.3e-05 24.3 20.9 7.4e-05 22.6 12.8 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO27631.1 - 0.00017 21.4 14.6 0.00017 21.4 14.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO27631.1 - 0.00024 21.4 26.3 0.00075 19.8 16.3 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO27631.1 - 0.00074 19.5 8.4 0.00074 19.5 8.4 4.0 4 0 0 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO27631.1 - 0.004 17.0 17.6 1.4 8.8 13.3 3.8 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 EGO27631.1 - 0.0071 16.6 3.4 15 6.0 0.0 4.2 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-WRNIP1_ubi PF18279.1 EGO27631.1 - 0.026 15.2 2.8 3.4 8.5 0.1 3.4 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain GAGA PF09237.11 EGO27631.1 - 0.077 12.8 2.3 11 6.0 0.0 3.5 3 0 0 3 3 3 0 GAGA factor zf-Nse PF11789.8 EGO27631.1 - 0.096 12.5 12.7 0.16 11.8 6.0 3.2 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit TRAF_BIRC3_bd PF16673.5 EGO27631.1 - 0.9 9.4 0.0 0.9 9.4 0.0 2.7 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Zn-C2H2_12 PF18112.1 EGO27631.1 - 3 8.4 12.6 4.9 7.7 1.0 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_4 PF15227.6 EGO27631.1 - 3.9 7.7 19.3 2.9 8.1 12.3 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGO27631.1 - 4.1 7.3 17.9 0.037 13.9 9.0 2.2 3 0 0 3 3 2 0 zf-RING of BARD1-type protein Tom7 PF08038.12 EGO27632.1 - 3.6e-21 74.5 0.6 4e-21 74.4 0.6 1.0 1 0 0 1 1 1 1 TOM7 family JAB PF01398.21 EGO27633.1 - 2.8e-23 82.2 0.1 5.5e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGO27633.1 - 3.9e-13 49.8 0.0 7.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function AFG1_ATPase PF03969.16 EGO27634.1 - 4.3e-99 331.8 0.0 2.5e-95 319.4 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EGO27634.1 - 0.00017 22.0 1.4 0.14 12.5 0.0 3.0 3 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 EGO27634.1 - 0.011 16.1 0.0 0.05 14.0 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO27634.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EGO27634.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 EGO27634.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Bac_DnaA PF00308.18 EGO27634.1 - 0.12 12.2 0.4 0.76 9.6 0.2 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein ABM PF03992.16 EGO27635.1 - 4e-06 26.9 0.0 0.0015 18.6 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SBDS PF01172.18 EGO27636.1 - 2.6e-19 69.1 0.0 3.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MutL_C PF08676.11 EGO27637.1 - 5e-06 26.3 0.0 8.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EGO27638.1 - 2.6e-09 37.0 0.0 3.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGO27638.1 - 3.9e-07 30.6 0.0 5.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carboxyl_trans PF01039.22 EGO27639.1 - 7.5e-131 437.1 0.2 9.4e-131 436.8 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGO27639.1 - 0.00071 19.1 0.7 0.045 13.2 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ArfGap PF01412.18 EGO27640.1 - 1.1e-32 112.5 0.1 2.1e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Velvet PF11754.8 EGO27641.1 - 1.5e-91 306.8 14.8 3.7e-88 295.7 14.8 2.2 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.6 EGO27642.1 - 0.0026 17.9 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 EGO27642.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 PPR repeat HMG_box_2 PF09011.10 EGO27645.1 - 7.1e-14 52.2 11.0 4.6e-07 30.3 2.9 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 EGO27645.1 - 2e-13 50.5 18.5 1.3e-06 28.7 5.1 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box TBX PF12598.8 EGO27645.1 - 0.11 13.3 4.3 1.5 9.7 2.5 3.0 2 0 0 2 2 2 0 T-box transcription factor M16C_assoc PF08367.11 EGO27645.1 - 3.4 6.7 6.6 0.15 11.1 0.9 1.5 2 0 0 2 2 2 0 Peptidase M16C associated GRIM-19 PF06212.12 EGO27647.1 - 6.7e-31 107.0 0.0 7.9e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Orbi_NS3 PF01616.16 EGO27648.1 - 0.011 15.4 0.2 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 Orbivirus NS3 BRE1 PF08647.11 EGO27648.1 - 0.11 12.6 2.9 0.18 11.9 2.9 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.21 EGO27648.1 - 0.14 12.3 3.3 0.23 11.6 3.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor Fer4 PF00037.27 EGO27650.1 - 5.9e-14 51.2 17.5 1.9e-08 33.7 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGO27650.1 - 7.3e-13 48.9 10.2 1.5e-12 47.9 10.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGO27650.1 - 9.9e-11 42.4 9.3 2.5e-05 25.1 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGO27650.1 - 4.3e-09 36.4 33.0 1.2e-05 25.4 13.0 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGO27650.1 - 7.7e-09 35.5 21.4 2.5e-06 27.5 12.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGO27650.1 - 1.4e-08 35.1 3.2 0.0002 21.7 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGO27650.1 - 2e-08 34.3 10.2 3.5e-08 33.5 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGO27650.1 - 4.3e-07 29.7 17.8 0.00044 20.2 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGO27650.1 - 1.1e-06 28.4 11.9 0.0025 17.8 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGO27650.1 - 6.6e-06 26.2 11.0 0.00035 20.8 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGO27650.1 - 0.00011 22.7 10.8 0.015 15.8 12.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGO27650.1 - 0.001 19.6 10.9 0.17 12.5 0.7 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 EGO27650.1 - 0.016 15.4 5.5 1.2 9.4 0.4 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EGO27650.1 - 0.058 13.6 9.2 13 6.0 9.2 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGO27650.1 - 0.23 12.5 16.3 0.38 11.8 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EGO27650.1 - 0.48 11.3 11.9 1.7 9.5 1.5 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EGO27650.1 - 0.99 9.6 7.0 2.9 8.1 0.9 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Prefoldin_2 PF01920.20 EGO27651.1 - 8.8e-22 77.1 0.6 1.1e-21 76.7 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 EGO27651.1 - 0.013 15.1 3.2 0.55 9.8 0.4 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 EGO27651.1 - 0.027 15.0 2.2 1.4 9.5 0.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Prefoldin PF02996.17 EGO27651.1 - 0.054 13.4 0.4 0.28 11.1 0.4 1.8 1 1 0 1 1 1 0 Prefoldin subunit DASH_Dad3 PF08656.10 EGO27651.1 - 0.08 13.0 0.2 0.15 12.1 0.1 1.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 CAP PF00188.26 EGO27652.1 - 1.5e-17 64.6 0.8 5.6e-17 62.8 0.8 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family F-box PF00646.33 EGO27653.1 - 1.1e-06 28.3 1.8 5.5e-06 26.1 0.8 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGO27653.1 - 2.3e-05 24.2 1.0 6e-05 22.8 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGO27653.1 - 0.0062 16.4 0.1 0.0062 16.4 0.1 2.3 2 0 0 2 2 2 1 F-box zf-H2C2_2 PF13465.6 EGO27654.1 - 1e-07 32.0 16.8 0.0049 17.2 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGO27654.1 - 6.7e-07 29.4 16.2 0.00017 21.8 0.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO27654.1 - 0.00095 19.8 14.8 0.013 16.3 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO27654.1 - 0.092 13.1 2.1 1.7 9.0 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF448 PF04296.13 EGO27654.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF448) FOXP-CC PF16159.5 EGO27654.1 - 0.31 11.7 1.7 3.7 8.2 0.1 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 EGO27654.1 - 0.99 9.9 3.5 2.2 8.8 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SPX PF03105.19 EGO27654.1 - 2.1 8.2 6.3 2.3 8.0 6.3 1.2 1 0 0 1 1 1 0 SPX domain RAP1 PF07218.11 EGO27654.1 - 4 5.6 5.8 4.8 5.3 5.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UCH PF00443.29 EGO27655.1 - 8.2e-18 64.8 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO27655.1 - 3e-07 30.3 0.3 2.4e-06 27.4 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PP2C PF00481.21 EGO27656.1 - 3.6e-30 105.5 0.0 2.4e-27 96.2 0.0 2.7 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGO27656.1 - 7.4e-06 25.7 0.0 1.9e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C ACT_7 PF13840.6 EGO27659.1 - 3.7e-19 68.3 0.0 1.2e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EGO27659.1 - 0.092 12.5 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 ACT domain Castor1_N PF18700.1 EGO27659.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain CcdB PF01845.17 EGO27659.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 CcdB protein adh_short PF00106.25 EGO27661.1 - 6.3e-45 153.0 0.1 9.4e-45 152.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO27661.1 - 4.8e-29 101.6 0.0 7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO27661.1 - 2.1e-11 44.0 1.2 4.7e-10 39.7 1.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO27661.1 - 0.0036 16.8 0.1 0.0098 15.4 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family baeRF_family8 PF18851.1 EGO27662.1 - 0.051 13.6 0.6 1 9.5 0.1 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 SKN1 PF03935.15 EGO27663.1 - 1e-163 545.4 8.1 1.3e-163 545.1 8.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_M22 PF00814.25 EGO27664.1 - 2.8e-84 283.0 0.0 3.3e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGO27664.1 - 0.098 12.3 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Pex14_N PF04695.13 EGO27665.1 - 4.6e-10 40.4 0.1 4.6e-10 40.4 0.1 3.4 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DEC-1_N PF04625.13 EGO27665.1 - 0.49 9.3 3.9 0.99 8.3 3.9 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region F-box-like PF12937.7 EGO27667.1 - 0.00084 19.2 4.3 0.00085 19.2 2.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGO27667.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.4 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 EGO27667.1 - 0.17 12.5 5.6 14 6.7 0.0 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 EGO27667.1 - 0.67 10.5 11.1 3.6 8.1 0.0 5.1 5 1 3 8 8 8 0 Leucine Rich repeats (2 copies) TFR_dimer PF04253.15 EGO27668.1 - 2.3e-23 82.6 2.6 6.1e-22 78.0 0.0 2.7 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGO27668.1 - 3.1e-15 56.4 0.2 3.8e-14 52.8 0.0 2.7 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EGO27668.1 - 1.4e-10 41.0 0.3 4.6e-10 39.4 0.3 1.9 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 EGO27668.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Nicastrin LMBR1 PF04791.16 EGO27668.1 - 0.026 13.4 0.1 0.037 13.0 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spectrin PF00435.21 EGO27668.1 - 0.048 14.2 1.2 0.13 12.7 1.2 1.7 1 0 0 1 1 1 0 Spectrin repeat RCS1 PF07326.11 EGO27668.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Alpha-amylase_C PF02806.18 EGO27669.1 - 1.9e-26 92.3 0.2 7.3e-26 90.5 0.1 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EGO27669.1 - 1e-19 70.6 0.0 2.8e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EGO27669.1 - 4.9e-14 52.6 0.1 9e-11 41.9 0.1 2.8 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Haspin_kinase PF12330.8 EGO27670.1 - 1.4e-59 201.9 0.0 2.5e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 EGO27670.1 - 0.06 12.6 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Sld5 PF05916.11 EGO27671.1 - 6.8e-23 81.2 0.5 9.6e-23 80.7 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein Ion_trans PF00520.31 EGO27672.1 - 0.00023 20.5 15.4 0.00023 20.5 15.4 2.4 2 1 0 2 2 2 1 Ion transport protein P21-Arc PF04062.14 EGO27673.1 - 7.1e-78 260.6 0.0 7.9e-78 260.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Metallophos_3 PF14582.6 EGO27673.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Iso_dh PF00180.20 EGO27674.1 - 4e-118 394.6 0.0 5e-118 394.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps5 PF09325.10 EGO27675.1 - 2.8e-17 63.0 3.2 3.8e-17 62.6 3.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGO27675.1 - 5e-12 45.8 0.2 1.6e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 PX domain Baculo_F PF12259.8 EGO27675.1 - 0.069 11.7 1.8 0.094 11.2 1.8 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF4570 PF15134.6 EGO27675.1 - 8.8 6.4 8.4 3.3 7.8 4.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) GTP_cyclohydro2 PF00925.20 EGO27676.1 - 1.2e-60 203.9 0.0 1.8e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II TFR_dimer PF04253.15 EGO27680.1 - 1.6e-21 76.7 1.3 1.1e-18 67.5 0.0 2.6 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGO27680.1 - 1.2e-18 67.6 0.0 1.2e-17 64.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 KxDL PF10241.9 EGO27680.1 - 0.037 14.3 0.6 0.12 12.7 0.6 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein Nicastrin PF05450.15 EGO27680.1 - 0.065 12.7 0.4 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Nicastrin AA_permease_C PF13906.6 EGO27681.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 C-terminus of AA_permease NUDIX PF00293.28 EGO27682.1 - 4.9e-16 59.0 0.0 6.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Spermine_synth PF01564.17 EGO27683.1 - 8.3e-08 31.9 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EGO27683.1 - 0.081 12.8 0.1 1.6 8.5 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain DIOX_N PF14226.6 EGO27684.1 - 6e-24 85.1 0.0 9.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO27684.1 - 7.6e-17 61.7 0.0 1.5e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RCC1 PF00415.18 EGO27685.1 - 4.5e-58 193.7 6.5 3.4e-10 40.4 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO27685.1 - 7.8e-33 111.6 38.9 3.7e-06 26.6 1.8 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EGO27685.1 - 0.13 11.9 0.0 5.3 6.7 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split Aldedh PF00171.22 EGO27686.1 - 4.5e-147 490.3 0.0 5.4e-147 490.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO27686.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Snf7 PF03357.21 EGO27687.1 - 2.6e-45 154.1 13.2 3.1e-45 153.9 13.2 1.0 1 0 0 1 1 1 1 Snf7 FlaC_arch PF05377.11 EGO27687.1 - 0.013 15.9 6.6 0.79 10.2 0.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EGO27687.1 - 0.018 15.0 12.8 0.84 9.6 0.0 3.6 2 1 0 3 3 3 0 Prefoldin subunit Ca_bind_SSO6904 PF18249.1 EGO27687.1 - 0.037 14.4 0.1 0.079 13.3 0.1 1.6 1 0 0 1 1 1 0 Calcium binding protein SSO6904 Metalloenzyme PF01676.18 EGO27687.1 - 0.12 11.7 0.5 0.25 10.7 0.4 1.5 1 1 0 1 1 1 0 Metalloenzyme superfamily Osmo_CC PF08946.10 EGO27687.1 - 0.28 11.5 4.6 23 5.3 0.0 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil TRPM_tetra PF16519.5 EGO27687.1 - 0.49 10.5 3.0 0.79 9.9 0.4 2.6 3 0 0 3 3 3 0 Tetramerisation domain of TRPM APG6_N PF17675.1 EGO27687.1 - 0.68 10.5 17.8 8.2 7.0 1.6 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2730 PF10805.8 EGO27687.1 - 1 9.5 4.7 1.4 9.0 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF5344 PF17279.2 EGO27687.1 - 1.2 9.8 11.4 1.6 9.4 4.9 3.1 1 1 0 2 2 2 0 Family of unknown function (DUF5344) GPS2_interact PF15784.5 EGO27687.1 - 1.3 9.5 8.3 0.3 11.5 1.4 2.5 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain BST2 PF16716.5 EGO27687.1 - 3.4 8.3 10.8 42 4.8 7.6 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 LMBR1 PF04791.16 EGO27687.1 - 9.7 5.0 5.3 11 4.8 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Abhydrolase_1 PF00561.20 EGO27690.1 - 7.6e-40 137.2 0.0 2.2e-39 135.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGO27690.1 - 0.0019 17.9 0.2 0.0031 17.2 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Snf7 PF03357.21 EGO27691.1 - 8e-10 38.6 13.2 1.1e-09 38.1 13.2 1.3 1 0 0 1 1 1 1 Snf7 BLOC1S3 PF15753.5 EGO27691.1 - 0.0049 17.0 0.9 0.0049 17.0 0.9 1.8 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 DMSP_lyase PF16867.5 EGO27691.1 - 0.0089 15.7 1.0 0.077 12.6 0.0 2.1 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 EGO27691.1 - 0.028 14.4 3.3 0.045 13.7 3.3 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Erv26 PF04148.13 EGO27692.1 - 1.5e-58 198.0 11.5 1.9e-58 197.7 11.5 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 EGO27692.1 - 0.026 14.4 1.0 0.079 12.9 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) MULE PF10551.9 EGO27694.1 - 0.0065 16.9 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Phage_holin_6_1 PF09682.10 EGO27694.1 - 0.19 12.2 1.2 0.43 11.0 1.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) MLVIN_C PF18697.1 EGO27695.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3527 PF12043.8 EGO27697.1 - 0.0011 18.6 0.2 0.0013 18.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) BUD22 PF09073.10 EGO27699.1 - 0.016 14.6 10.7 0.022 14.1 10.7 1.3 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 EGO27699.1 - 0.019 15.1 12.1 0.032 14.4 12.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 EGO27699.1 - 1.8 7.5 8.0 0.82 8.7 5.8 1.5 2 0 0 2 2 2 0 Pes-10 Syja_N PF02383.18 EGO27701.1 - 1.2e-70 238.4 0.0 1.6e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain SF3a60_bindingd PF12108.8 EGO27702.1 - 1.2e-06 28.3 0.1 1.8e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Jnk-SapK_ap_N PF09744.9 EGO27702.1 - 0.0023 18.2 2.1 0.0026 18.0 2.1 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF4254 PF14063.6 EGO27702.1 - 0.02 14.7 1.4 0.076 12.8 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) NaeI PF09126.10 EGO27702.1 - 0.058 12.6 0.6 0.069 12.3 0.6 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI PRP9_N PF16958.5 EGO27702.1 - 0.074 13.1 3.0 0.091 12.8 3.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus DEAD PF00270.29 EGO27703.1 - 1.2e-43 148.9 0.1 2e-43 148.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO27703.1 - 2.5e-31 108.3 0.1 1.1e-30 106.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGO27703.1 - 0.00016 22.0 0.1 0.0074 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EGO27703.1 - 0.00026 21.1 0.0 0.00061 19.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGO27703.1 - 0.0036 17.0 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO27703.1 - 0.08 13.2 0.7 0.47 10.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EGO27703.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RRM_1 PF00076.22 EGO27706.1 - 2.3e-18 65.8 0.1 2.3e-18 65.8 0.1 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO27706.1 - 2.1e-08 33.8 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO27706.1 - 0.079 13.0 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 RNA binding motif RRM_8 PF11835.8 EGO27706.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 1 1 2 2 2 0 RRM-like domain DUF2076 PF09849.9 EGO27707.1 - 0.037 14.1 0.3 0.046 13.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Aldedh PF00171.22 EGO27709.1 - 3.5e-157 523.6 0.6 4e-157 523.4 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF596 PF04591.12 EGO27710.1 - 0.026 14.7 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Nop14 PF04147.12 EGO27713.1 - 3 5.9 10.6 3.9 5.6 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EGO27713.1 - 5.1 6.9 7.8 8.7 6.2 7.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EGO27713.1 - 9.5 5.5 11.4 12 5.2 11.4 1.1 1 0 0 1 1 1 0 SDA1 DUF4666 PF15697.5 EGO27715.1 - 0.19 12.4 0.0 0.4 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) BTG PF07742.12 EGO27717.1 - 6e-15 55.1 0.0 1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 BTG family WD40 PF00400.32 EGO27718.1 - 1.4e-11 44.7 5.2 0.11 13.4 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO27718.1 - 8.9e-08 32.3 0.0 0.0038 17.5 0.0 3.9 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO27718.1 - 0.00022 21.1 0.0 0.32 11.0 0.0 3.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGO27718.1 - 0.0012 18.7 0.0 0.63 9.9 0.0 2.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGO27718.1 - 0.02 12.9 0.0 0.52 8.2 0.0 2.4 2 1 1 3 3 3 0 IKI3 family Cytochrom_D1 PF02239.16 EGO27718.1 - 0.031 12.8 0.0 0.086 11.4 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Dehalogenase PF13486.6 EGO27718.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit DUF2850 PF11012.8 EGO27718.1 - 0.13 12.5 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) tRNA-synt_1d PF00750.19 EGO27718.1 - 0.22 10.4 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) Abhydrolase_1 PF00561.20 EGO27719.1 - 2.2e-20 73.4 0.4 4.9e-20 72.3 0.4 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO27719.1 - 1.7e-10 41.9 0.3 2.1e-10 41.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EGO27719.1 - 4.9e-08 32.0 0.0 6.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 EGO27719.1 - 3.5e-06 26.5 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TFIIB PF00382.19 EGO27722.1 - 4.5e-36 122.7 0.0 1e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGO27722.1 - 8.4e-14 50.8 1.4 1.4e-13 50.1 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.20 EGO27722.1 - 0.00077 19.3 0.1 3.3 7.7 0.0 3.1 3 0 0 3 3 3 2 Bacterial regulatory protein, arsR family Cyclin_C PF02984.19 EGO27722.1 - 0.014 15.5 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain Guanylin PF02058.15 EGO27722.1 - 0.014 15.8 1.8 5.9 7.4 0.1 3.0 1 1 2 3 3 3 0 Guanylin precursor Cyclin_N PF00134.23 EGO27722.1 - 0.062 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain RB_B PF01857.20 EGO27722.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_Tnp_ISL3 PF13542.6 EGO27722.1 - 0.17 11.3 0.0 13 5.3 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 RRS1 PF04939.12 EGO27723.1 - 9.9e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TIP41 PF04176.13 EGO27724.1 - 1.5e-62 210.1 0.0 1.9e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.11 EGO27725.1 - 7.9e-39 133.8 8.9 1.8e-30 106.2 0.0 4.3 2 2 1 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 EGO27725.1 - 0.0098 16.3 0.2 0.026 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 EGO27725.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase KTI12 PF08433.10 EGO27725.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Hep_59 PF07052.11 EGO27727.1 - 1.8e-28 99.4 2.1 1.8e-28 99.4 2.1 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Pro-kuma_activ PF09286.11 EGO27729.1 - 1.6e-37 128.9 0.0 4.3e-37 127.6 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain PCI PF01399.27 EGO27730.1 - 6.5e-14 52.3 0.1 3.6e-13 49.9 0.0 2.2 2 1 1 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 EGO27730.1 - 7.4e-08 31.9 0.1 2.1e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix R3H-assoc PF13902.6 EGO27730.1 - 0.051 13.9 0.1 0.84 10.0 0.0 2.2 2 0 0 2 2 2 0 R3H-associated N-terminal domain ASD2 PF08687.11 EGO27730.1 - 0.065 12.8 2.0 0.075 12.6 0.6 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DUF2009 PF09418.10 EGO27731.1 - 8.3e-212 704.2 0.0 9.8e-212 704.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EGO27731.1 - 5.8e-06 26.4 6.0 1.1e-05 25.5 6.0 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 EGO27731.1 - 0.0009 19.4 4.9 0.0019 18.4 4.9 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-HIT PF04438.16 EGO27731.1 - 0.027 14.3 3.3 0.055 13.3 3.3 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C3HC4_3 PF13920.6 EGO27731.1 - 0.45 10.4 5.8 0.89 9.5 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) STIMATE PF12400.8 EGO27732.1 - 5.3e-37 127.2 4.0 8.3e-37 126.5 4.0 1.3 1 0 0 1 1 1 1 STIMATE family AAA PF00004.29 EGO27733.1 - 4.7e-53 179.1 0.0 1.3e-39 135.7 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO27733.1 - 4.4e-12 46.5 0.2 2.4e-05 24.7 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EGO27733.1 - 8e-11 42.6 0.1 0.0021 18.5 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 EGO27733.1 - 6.5e-09 35.5 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGO27733.1 - 9.2e-09 35.6 0.0 9e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGO27733.1 - 6.6e-08 32.6 0.1 0.0017 18.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO27733.1 - 1.2e-07 31.6 0.1 0.021 14.6 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGO27733.1 - 2.8e-07 30.8 0.0 0.0095 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGO27733.1 - 5.5e-07 29.1 0.0 0.02 14.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EGO27733.1 - 1.4e-06 28.8 0.0 0.028 15.0 0.0 3.0 2 1 1 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EGO27733.1 - 1.6e-06 27.7 0.3 0.0067 15.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGO27733.1 - 2e-06 28.4 0.0 0.038 14.5 0.1 2.9 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 EGO27733.1 - 1.2e-05 25.3 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGO27733.1 - 3e-05 24.4 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_11 PF13086.6 EGO27733.1 - 4.2e-05 23.5 0.1 0.097 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGO27733.1 - 5.8e-05 22.9 0.1 0.3 10.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EGO27733.1 - 7.1e-05 22.6 0.1 0.046 13.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGO27733.1 - 0.0001 22.1 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 EGO27733.1 - 0.00013 21.7 0.1 0.26 11.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 EGO27733.1 - 0.00016 21.1 0.2 0.021 14.2 0.1 2.5 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 EGO27733.1 - 0.00018 21.5 4.4 0.32 10.9 0.1 3.5 5 0 0 5 5 3 2 NACHT domain AAA_3 PF07726.11 EGO27733.1 - 0.00021 21.2 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGO27733.1 - 0.00021 21.3 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain CDC48_2 PF02933.17 EGO27733.1 - 0.00041 20.1 0.1 0.0086 15.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.6 EGO27733.1 - 0.00042 19.9 1.1 2.9 7.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 EGO27733.1 - 0.00048 19.4 0.1 0.31 10.2 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 EGO27733.1 - 0.00052 19.6 0.1 0.061 12.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGO27733.1 - 0.0011 19.3 0.0 0.52 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EGO27733.1 - 0.0014 18.1 0.0 0.91 8.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 EGO27733.1 - 0.0025 17.1 0.3 0.63 9.2 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGO27733.1 - 0.0034 16.5 0.1 1.3 8.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGO27733.1 - 0.0037 17.6 0.6 1.6 9.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGO27733.1 - 0.0047 16.9 0.1 27 4.5 0.0 3.9 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea Hydin_ADK PF17213.3 EGO27733.1 - 0.0065 16.8 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain CPT PF07931.12 EGO27733.1 - 0.0072 16.2 0.1 0.6 9.9 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EGO27733.1 - 0.0093 16.0 0.0 0.59 10.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EGO27733.1 - 0.016 14.5 0.4 1.9 7.8 0.1 2.6 2 1 0 2 2 2 0 Zeta toxin Torsin PF06309.11 EGO27733.1 - 0.017 15.2 0.0 9.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 EGO27733.1 - 0.021 13.9 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PduV-EutP PF10662.9 EGO27733.1 - 0.025 14.3 0.6 30 4.4 0.0 4.0 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 EGO27733.1 - 0.029 14.1 0.0 9.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EGO27733.1 - 0.037 13.4 0.0 7.4 5.9 0.0 3.2 2 1 0 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 EGO27733.1 - 0.038 14.4 0.9 6.3 7.2 0.0 3.5 5 0 0 5 5 2 0 AAA domain cobW PF02492.19 EGO27733.1 - 0.05 13.2 0.1 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EGO27733.1 - 0.051 13.5 0.1 7 6.5 0.0 2.7 2 0 0 2 2 2 0 NTPase AFG1_ATPase PF03969.16 EGO27733.1 - 0.058 12.3 0.0 7.4 5.3 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Rad17 PF03215.15 EGO27733.1 - 0.066 13.1 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain SKI PF01202.22 EGO27733.1 - 0.076 13.1 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.10 EGO27733.1 - 0.11 11.9 0.0 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 EGO27733.1 - 0.12 12.1 0.0 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 EGO27733.1 - 0.12 12.1 0.2 11 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.9 EGO27733.1 - 0.18 10.9 0.1 20 4.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 IPP-2 PF04979.14 EGO27734.1 - 8e-19 68.7 0.2 1.4e-18 67.9 0.2 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) THF_DHG_CYH PF00763.23 EGO27735.1 - 9.8e-26 90.3 0.0 1.5e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGO27735.1 - 2e-17 63.0 0.3 1.3e-09 37.6 0.0 2.7 1 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EGO27735.1 - 0.028 14.5 0.1 0.75 9.8 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase PLU-1 PF08429.11 EGO27739.1 - 3.7e-54 184.2 2.0 2.7e-53 181.3 2.0 2.3 1 1 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 EGO27739.1 - 2.6e-42 143.8 1.6 4.9e-42 143.0 0.5 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 EGO27739.1 - 1.8e-18 67.0 0.0 5.2e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EGO27739.1 - 1e-15 57.4 0.1 2.9e-15 55.9 0.1 1.9 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EGO27739.1 - 5.2e-15 55.1 39.8 2e-11 43.6 8.5 4.6 4 0 0 4 4 4 2 PHD-finger zf-C5HC2 PF02928.16 EGO27739.1 - 7.9e-13 48.6 9.3 7.9e-13 48.6 9.3 2.9 3 0 0 3 3 3 1 C5HC2 zinc finger PHD_2 PF13831.6 EGO27739.1 - 3.8 7.1 18.4 1.3 8.7 1.8 3.8 3 0 0 3 3 3 0 PHD-finger CorA PF01544.18 EGO27740.1 - 3.2e-46 158.0 0.5 4.1e-46 157.6 0.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EGO27740.1 - 0.0049 16.9 0.3 0.011 15.8 0.1 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.7 EGO27740.1 - 0.13 12.4 0.4 0.26 11.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) DUF3561 PF12084.8 EGO27743.1 - 0.14 12.1 2.9 0.17 11.9 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3561) PGAP1 PF07819.13 EGO27744.1 - 7.1e-57 192.8 0.0 9.1e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO27744.1 - 3.8e-08 34.2 1.0 6.1e-08 33.5 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO27744.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO27744.1 - 0.00063 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EGO27744.1 - 0.0095 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF915 PF06028.11 EGO27744.1 - 0.032 13.6 0.0 0.67 9.2 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EGO27744.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) 14-3-3 PF00244.20 EGO27746.1 - 2.7e-107 357.3 4.7 3.1e-107 357.1 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.25 EGO27746.1 - 0.26 11.3 1.3 1.7 8.8 0.1 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain CLPTM1 PF05602.12 EGO27748.1 - 8.9e-130 433.5 0.0 1.1e-129 433.3 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGO27748.1 - 0.00045 19.9 0.3 0.0011 18.8 0.3 1.6 1 0 0 1 1 1 1 PQ loop repeat 2TM PF13239.6 EGO27748.1 - 9.9 6.6 9.8 0.47 10.8 1.4 3.0 2 1 1 3 3 3 0 2TM domain Utp8 PF10395.9 EGO27749.1 - 0.0013 17.3 0.0 0.0024 16.5 0.0 1.3 1 0 0 1 1 1 1 Utp8 family Elongin_A PF06881.11 EGO27749.1 - 0.022 15.3 0.1 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MA3 PF02847.17 EGO27749.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 MA3 domain MoCF_biosynth PF00994.24 EGO27750.1 - 6.5e-61 204.2 0.3 1.6e-30 105.7 0.1 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGO27750.1 - 8e-36 123.2 0.1 1.4e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGO27750.1 - 5.4e-13 48.9 0.4 1.5e-12 47.5 0.2 1.9 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Peptidase_S10 PF00450.22 EGO27752.1 - 7.6e-100 335.2 0.0 1e-99 334.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.16 EGO27752.1 - 0.00062 18.6 0.0 0.00093 18.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RET_CLD1 PF17756.1 EGO27752.1 - 0.19 12.0 0.0 0.5 10.7 0.0 1.6 1 0 0 1 1 1 0 RET Cadherin like domain 1 Ldr_toxin PF13940.6 EGO27753.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system Ribosomal_L13 PF00572.18 EGO27754.1 - 3.9e-50 169.3 0.3 5e-50 168.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 SMC_N PF02463.19 EGO27756.1 - 1.1e-19 70.8 0.0 3.2e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO27756.1 - 2.4e-18 67.4 0.0 2.4e-18 67.4 0.0 4.7 2 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGO27756.1 - 1.5e-06 28.2 3.8 1.5e-06 28.2 3.8 3.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGO27756.1 - 0.0053 16.5 0.1 0.035 13.9 0.0 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGO27756.1 - 0.018 14.8 0.0 0.084 12.6 0.0 2.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 EGO27756.1 - 0.095 13.1 2.8 1.4 9.4 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EGO27756.1 - 1.9 8.2 7.5 0.39 10.5 0.2 3.0 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Pullulanase_Ins PF18494.1 EGO27756.1 - 5.2 7.6 5.9 17 5.9 0.0 3.7 3 0 0 3 3 3 0 Pullulanase Ins domain WHEP-TRS PF00458.20 EGO27756.1 - 5.4 7.2 8.5 11 6.2 1.5 3.1 2 0 0 2 2 2 0 WHEP-TRS domain Semialdhyde_dh PF01118.24 EGO27757.1 - 4.7e-19 69.0 0.0 5.3e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGO27757.1 - 0.023 14.8 0.0 0.026 14.7 0.0 1.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 EGO27757.1 - 0.03 15.1 0.0 0.032 15.0 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.23 EGO27757.1 - 0.093 12.8 0.0 0.11 12.6 0.0 1.3 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGO27757.1 - 0.099 12.9 0.1 0.099 12.9 0.1 1.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGO27757.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding Rab5ip PF07019.12 EGO27758.1 - 4.5e-20 72.0 6.0 5.5e-20 71.7 6.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_2 PF07719.17 EGO27760.1 - 3.8e-12 45.3 6.2 0.00031 20.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO27760.1 - 4e-11 42.2 0.0 0.0033 17.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO27760.1 - 6.4e-07 29.7 7.3 0.037 14.8 0.0 6.7 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO27760.1 - 1.1e-06 29.2 0.0 1.1e-06 29.2 0.0 4.3 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO27760.1 - 1.8e-06 28.2 0.6 0.0089 16.3 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO27760.1 - 4.1e-06 26.6 0.0 0.053 13.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO27760.1 - 7.2e-06 26.0 0.1 0.071 13.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO27760.1 - 2.5e-05 23.9 0.0 0.012 15.3 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 EGO27760.1 - 3.7e-05 24.2 0.0 3.8 8.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO27760.1 - 9.8e-05 22.1 3.1 0.037 13.9 0.0 5.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO27760.1 - 0.00014 21.9 0.0 0.0068 16.5 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO27760.1 - 0.0064 17.0 0.0 1.1 10.0 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO27760.1 - 0.0092 15.9 5.1 9.2 6.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 EGO27760.1 - 0.12 12.1 0.0 9.9 5.8 0.0 3.7 5 0 0 5 5 5 0 26S proteasome subunit RPN7 4HBT PF03061.22 EGO27761.1 - 2.5e-07 30.9 0.1 4.3e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.22 EGO27762.1 - 0.093 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Ham1p_like PF01725.16 EGO27763.1 - 5.8e-57 192.6 0.0 6.6e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RNA_pol_Rpb1_5 PF04998.17 EGO27765.1 - 1.7e-83 280.2 0.0 3.4e-83 279.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGO27765.1 - 2e-52 177.7 0.2 3.7e-52 176.9 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGO27765.1 - 1e-36 126.3 0.0 2.5e-36 125.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGO27765.1 - 3.1e-30 105.6 1.2 1.1e-23 84.1 0.1 3.5 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGO27765.1 - 9.3e-21 73.8 0.0 2.8e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF5102 PF17104.5 EGO27766.1 - 2.6e-63 214.8 4.2 3.1e-63 214.5 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 EGO27766.1 - 0.0022 17.8 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 FEZ-like protein GGA_N-GAT PF18308.1 EGO27766.1 - 0.18 11.4 0.4 0.71 9.5 0.2 2.1 2 0 0 2 2 2 0 GGA N-GAT domain RNA_pol_I_TF PF04090.12 EGO27767.1 - 2.1e-11 43.7 0.9 4.4e-08 32.8 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_19 PF14559.6 EGO27767.1 - 0.0065 17.0 2.3 3 8.4 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TAF1_subA PF14929.6 EGO27767.1 - 0.045 13.2 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 EGO27767.1 - 0.053 14.4 2.3 2.7 9.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UPA PF17217.3 EGO27767.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 UPA domain TPR_2 PF07719.17 EGO27767.1 - 0.16 12.1 0.8 2.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RIX1 PF08167.12 EGO27768.1 - 2.6e-40 138.2 6.7 2.6e-40 138.2 6.7 2.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec10 PF07393.11 EGO27769.1 - 9.3e-225 748.3 0.0 1.2e-224 747.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1664 PF07889.12 EGO27769.1 - 0.088 12.8 1.9 0.4 10.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GNAT_like PF18407.1 EGO27769.1 - 4 7.9 5.8 0.55 10.6 0.4 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain ECH_1 PF00378.20 EGO27770.1 - 2.7e-54 184.2 0.0 3.2e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO27770.1 - 1.4e-28 100.4 0.1 8.4e-28 97.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CLP_protease PF00574.23 EGO27770.1 - 0.21 11.5 0.1 20 5.0 0.0 2.3 1 1 1 2 2 2 0 Clp protease DUF4398 PF14346.6 EGO27770.1 - 0.59 10.8 3.7 0.28 11.8 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) RicinB_lectin_2 PF14200.6 EGO27773.1 - 6.1e-07 30.1 6.0 9.3e-05 23.1 1.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 EGO27774.1 - 5e-09 36.8 6.6 4.9e-05 24.0 0.4 3.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like PGDYG PF14083.6 EGO27774.1 - 0.023 14.9 0.2 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 PGDYG protein SpaA PF17802.1 EGO27774.1 - 0.06 13.7 0.3 0.06 13.7 0.3 2.5 2 1 0 2 2 2 0 Prealbumin-like fold domain FAM83 PF07894.12 EGO27774.1 - 0.061 12.9 0.1 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 FAM83 A-H Polyketide_cyc2 PF10604.9 EGO27774.1 - 0.078 13.2 0.1 0.37 11.1 0.0 2.2 2 1 1 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport DUF3283 PF11686.8 EGO27774.1 - 0.12 12.2 0.1 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) GPI-anchored PF10342.9 EGO27774.1 - 0.13 13.1 9.7 7.8 7.3 2.2 4.4 3 1 1 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DDE_Tnp_IS66 PF03050.14 EGO27775.1 - 0.11 12.0 3.4 0.14 11.6 3.4 1.1 1 0 0 1 1 1 0 Transposase IS66 family DDE_Tnp_4 PF13359.6 EGO27776.1 - 1.1e-20 73.9 0.0 1.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2293 PF10056.9 EGO27776.1 - 0.069 13.4 0.8 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) DTHCT PF08070.11 EGO27776.1 - 0.16 12.7 1.9 0.26 12.0 1.9 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region zf-CCHC PF00098.23 EGO27780.1 - 0.0039 17.2 4.2 0.0059 16.6 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO27780.1 - 0.033 14.5 0.1 0.094 13.0 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Peptidase_M60_C PF18630.1 EGO27780.1 - 0.037 14.1 0.1 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain DUF5417 PF17438.2 EGO27784.1 - 0.18 12.1 1.6 20 5.6 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5417) Retrotrans_gag PF03732.17 EGO27785.1 - 4.8e-08 33.2 0.2 4.8e-08 33.2 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein BMFP PF04380.13 EGO27785.1 - 0.16 12.5 0.9 52 4.4 0.0 3.4 3 0 0 3 3 3 0 Membrane fusogenic activity zf-CCHC PF00098.23 EGO27786.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO27786.1 - 0.0083 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO27786.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain DEAD PF00270.29 EGO27787.1 - 4.9e-06 26.4 0.1 5.8e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase QRPTase_C PF01729.19 EGO27788.1 - 1.4e-47 161.6 0.1 1.7e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGO27788.1 - 1.6e-19 69.7 0.0 5.4e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SIP1 PF04938.12 EGO27789.1 - 1.7e-23 83.5 0.0 1.9e-22 80.1 0.0 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DSPc PF00782.20 EGO27793.1 - 3.5e-31 107.8 0.0 4.1e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO27793.1 - 0.00039 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGO27793.1 - 0.003 17.8 0.2 0.0058 16.9 0.1 1.5 2 0 0 2 2 2 1 Rit1 DUSP-like domain Myotub-related PF06602.14 EGO27793.1 - 0.06 12.3 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain GBP_repeat PF02526.14 EGO27794.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 Glycophorin-binding protein Sec15 PF04091.12 EGO27795.1 - 1.8e-99 333.2 0.4 1.8e-99 333.2 0.4 2.4 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 EGO27795.1 - 7.5e-07 29.4 0.7 7.5e-07 29.4 0.7 3.2 3 1 1 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EGO27795.1 - 9.3e-06 25.6 0.4 9.3e-06 25.6 0.4 2.8 3 0 0 3 3 3 1 Vps51/Vps67 Sec8_exocyst PF04048.14 EGO27795.1 - 0.0002 21.3 0.4 0.0002 21.3 0.4 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 EGO27795.1 - 0.013 15.6 1.5 0.013 15.6 1.5 3.5 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 EGO27795.1 - 0.092 12.8 0.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 EGO27795.1 - 3.5 7.8 7.3 5.8 7.1 2.4 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HAD_2 PF13419.6 EGO27796.1 - 7.6e-23 81.5 0.0 9.6e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO27796.1 - 4.4e-13 50.0 0.2 9.3e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO27796.1 - 1.3e-06 28.4 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGO27796.1 - 0.017 15.5 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tubulin PF00091.25 EGO27797.1 - 2.6e-66 223.6 0.0 3.5e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO27797.1 - 1.5e-47 160.9 0.0 2.2e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGO27797.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 EGO27797.1 - 0.015 15.1 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Tubulin PF00091.25 EGO27798.1 - 9.9e-58 195.6 0.0 1.9e-57 194.7 0.0 1.5 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO27798.1 - 6e-49 165.4 0.0 9.5e-49 164.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGO27798.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 EGO27798.1 - 0.14 12.1 0.0 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.13 EGO27799.1 - 5.1e-33 114.7 0.3 3.3e-23 82.7 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO27799.1 - 7.8e-10 38.2 0.0 1.4e-08 34.1 0.1 2.7 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EGO27799.1 - 0.059 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family Lactamase_B_6 PF16661.5 EGO27800.1 - 4.6e-51 173.0 0.0 1.7e-48 164.7 0.0 3.0 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EGO27800.1 - 1.4e-24 87.2 15.7 8.6e-24 84.6 0.0 4.7 4 1 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EGO27800.1 - 3e-18 66.1 0.0 1.6e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EGO27800.1 - 4.8e-05 23.2 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EGO27800.1 - 0.013 15.0 0.1 1.2 8.5 0.0 2.6 1 1 2 3 3 3 0 Beta-lactamase superfamily domain tRNA-synt_1c PF00749.21 EGO27801.1 - 5.4e-110 367.2 0.0 7.1e-110 366.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EGO27801.1 - 1.1e-39 136.0 0.0 1.9e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EGO27801.1 - 6.6e-31 107.5 0.0 1.5e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EGO27801.1 - 5.6e-05 24.0 1.0 0.00016 22.5 1.0 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PAF-AH_p_II PF03403.13 EGO27802.1 - 2.5e-41 141.4 0.0 5.2e-41 140.4 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGO27802.1 - 4.9e-06 25.7 0.0 0.0065 15.4 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGO27802.1 - 7.1e-06 25.5 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EGO27802.1 - 0.0014 17.8 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.7 EGO27802.1 - 0.0019 18.8 0.7 0.009 16.6 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGO27802.1 - 0.024 14.8 0.0 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain DUF2985 PF11204.8 EGO27803.1 - 6.2e-27 93.6 2.0 1.4e-26 92.5 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Meth_synt_2 PF01717.18 EGO27804.1 - 9.8e-149 495.0 0.0 4e-145 483.1 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGO27804.1 - 3.1e-117 391.6 0.0 1.9e-110 369.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Rsd_AlgQ PF04353.13 EGO27804.1 - 0.1 12.5 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Pkinase PF00069.25 EGO27805.1 - 5.4e-50 170.2 0.0 6.9e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27805.1 - 4.5e-26 91.7 0.0 5.7e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO27805.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGO27805.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family ADH_N PF08240.12 EGO27806.1 - 1.9e-30 105.0 0.3 3.1e-30 104.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO27806.1 - 4.3e-24 84.9 0.1 6.7e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO27806.1 - 6.5e-07 30.5 0.1 1.4e-06 29.4 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO27806.1 - 1.4e-05 24.7 0.1 0.029 13.8 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 EGO27806.1 - 0.0024 18.5 0.0 0.0044 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 EGO27806.1 - 0.0037 16.6 0.3 0.0066 15.8 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.13 EGO27806.1 - 0.011 15.1 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.14 EGO27806.1 - 0.019 14.5 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.6 EGO27806.1 - 0.081 12.7 0.0 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EGO27806.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DTHCT PF08070.11 EGO27807.1 - 0.0033 18.1 6.3 0.01 16.6 6.3 1.8 1 0 0 1 1 1 1 DTHCT (NUC029) region NPR3 PF03666.13 EGO27807.1 - 2.7 6.7 4.6 3.9 6.2 4.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GTP_EFTU PF00009.27 EGO27808.1 - 2.2e-51 174.2 0.0 3.1e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGO27808.1 - 2.4e-14 53.1 0.0 9.4e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 EGO27808.1 - 7.2e-14 51.6 0.0 1.7e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGO27808.1 - 5.7e-07 29.8 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO27808.1 - 0.00031 20.8 0.8 0.00059 19.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 EGO27808.1 - 0.037 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EGO27808.1 - 0.14 11.6 0.0 0.43 10.0 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ICMT PF04140.14 EGO27809.1 - 1.4e-27 95.9 0.3 3.2e-27 94.8 0.3 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO27809.1 - 5.2e-12 46.1 1.0 5.2e-12 46.1 1.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 EGO27809.1 - 0.00011 21.8 0.8 0.00021 20.9 0.1 1.8 2 0 0 2 2 2 1 NnrU protein ERG4_ERG24 PF01222.17 EGO27809.1 - 0.00028 19.8 0.4 0.00045 19.1 0.4 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_L6 PF00347.23 EGO27810.1 - 2e-29 102.1 7.5 6.9e-16 58.7 2.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 BT1 PF03092.16 EGO27810.1 - 0.056 11.7 0.1 0.068 11.4 0.1 1.0 1 0 0 1 1 1 0 BT1 family CTD_bind PF04818.13 EGO27811.1 - 3.8e-05 24.4 0.0 0.00036 21.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 EGO27811.1 - 0.0034 17.8 0.0 0.021 15.3 0.0 2.4 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 PIN_4 PF13638.6 EGO27812.1 - 5.8e-21 75.1 0.0 8.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 PIN domain MFS_1 PF07690.16 EGO27813.1 - 1.8e-33 116.0 21.6 1.1e-32 113.3 12.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO27813.1 - 4.2e-10 39.1 0.5 4.2e-10 39.1 0.5 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 EGO27813.1 - 0.0007 18.6 0.2 0.0013 17.7 0.2 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TruD PF01142.18 EGO27814.1 - 6.8e-76 255.7 0.0 2.4e-72 244.1 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) OMPdecase PF00215.24 EGO27815.1 - 3.8e-70 236.0 0.0 4.8e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family eRF1_1 PF03463.15 EGO27816.1 - 1.1e-48 164.5 0.0 1.6e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EGO27816.1 - 7e-23 81.3 0.0 1.5e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EGO27816.1 - 1.7e-16 60.7 0.0 2.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Glyco_trans_4_2 PF13477.6 EGO27816.1 - 0.027 14.5 0.2 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like ETF PF01012.21 EGO27816.1 - 0.031 14.2 0.1 0.094 12.6 0.0 1.8 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Atg14 PF10186.9 EGO27816.1 - 0.066 12.3 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phosducin PF02114.16 EGO27817.1 - 0.018 14.0 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin PF00085.20 EGO27817.1 - 0.021 14.8 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin LIN52 PF10044.9 EGO27817.1 - 0.082 13.6 0.2 0.14 12.9 0.2 1.3 1 0 0 1 1 1 0 Retinal tissue protein CzcE PF16986.5 EGO27817.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE FAD_binding_7 PF03441.14 EGO27818.1 - 6.2e-75 251.1 0.8 1.1e-74 250.3 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGO27818.1 - 2.4e-33 115.5 0.0 4.3e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF5127 PF17168.4 EGO27819.1 - 2.5e-80 269.5 12.7 2.5e-80 269.5 12.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EGO27819.1 - 2.6e-76 255.1 2.3 7.6e-76 253.6 0.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EGO27819.1 - 9e-69 231.2 11.1 1.8e-68 230.2 2.9 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EGO27819.1 - 4.3e-09 35.8 0.6 1.3e-08 34.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Wtap PF17098.5 EGO27821.1 - 1.6e-16 60.6 4.0 3e-15 56.5 4.0 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family HAP1_N PF04849.13 EGO27821.1 - 0.024 13.8 1.5 0.03 13.5 0.3 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SKA1 PF07160.12 EGO27821.1 - 0.062 13.1 0.1 0.062 13.1 0.1 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 TMF_DNA_bd PF12329.8 EGO27821.1 - 0.13 12.3 1.1 24 5.0 0.0 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Nucleo_P87 PF07267.11 EGO27821.1 - 0.68 8.7 8.4 0.77 8.5 8.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WD40_alt PF14077.6 EGO27821.1 - 0.97 9.3 4.3 9.9 6.1 0.1 2.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF4407 PF14362.6 EGO27821.1 - 2.9 7.2 6.3 39 3.4 6.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_18 PF00704.28 EGO27823.1 - 3.6e-52 178.0 0.0 4.6e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DehI PF10778.9 EGO27823.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Zn_ribbon_SprT PF17283.2 EGO27824.1 - 0.0031 17.4 1.8 1.2 9.1 0.5 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain MFS_1 PF07690.16 EGO27826.1 - 1.9e-09 36.9 22.7 1.1e-07 31.1 22.7 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGO27826.1 - 2.9e-07 29.4 5.7 2.9e-07 29.4 5.7 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF2207 PF09972.9 EGO27826.1 - 0.76 8.5 0.0 0.76 8.5 0.0 2.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Reticulon PF02453.17 EGO27826.1 - 2.2 8.2 13.5 0.42 10.5 0.1 3.0 4 0 0 4 4 4 0 Reticulon Diphthami_syn_2 PF01902.17 EGO27827.1 - 1.8e-38 132.2 0.0 8.8e-30 103.8 0.0 2.2 1 1 1 2 2 2 2 Diphthamide synthase Asparaginase_C PF17763.1 EGO27827.1 - 0.03 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain tRNA_synthFbeta PF17759.1 EGO27828.1 - 1.4e-47 161.9 0.0 2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGO27828.1 - 2.2e-32 111.1 0.2 1.3e-31 108.7 0.0 2.1 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGO27828.1 - 3.7e-26 91.8 0.1 6.4e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGO27828.1 - 8.4e-17 61.2 0.0 4.1e-14 52.6 0.0 2.9 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 EGO27828.1 - 0.009 15.5 0.0 0.36 10.3 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF2370 PF10176.9 EGO27829.1 - 5e-74 248.7 0.0 9e-74 247.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Acetyltransf_1 PF00583.25 EGO27836.1 - 5.3e-12 46.0 0.0 1.2e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO27836.1 - 2.3e-10 40.5 0.0 3.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO27836.1 - 3.6e-09 36.9 0.0 9.8e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO27836.1 - 5.1e-08 32.8 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGO27836.1 - 2.9e-05 24.8 0.0 0.00036 21.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGO27836.1 - 0.00049 19.8 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EGO27836.1 - 0.00074 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGO27836.1 - 0.02 15.0 0.1 0.054 13.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EGO27836.1 - 0.058 13.1 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 MOZ/SAS family zinc_ribbon_11 PF11682.8 EGO27836.1 - 0.16 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Probable zinc-ribbon Retrotrans_gag PF03732.17 EGO27837.1 - 0.0051 17.1 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 EGO27838.1 - 2.1e-06 28.2 0.0 3.2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO27838.1 - 2.1e-06 27.6 0.0 2.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO27838.1 - 8e-05 23.2 0.0 0.00011 22.7 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease Acetyltransf_1 PF00583.25 EGO27840.1 - 5.2e-12 46.0 0.0 1.2e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO27840.1 - 2.7e-10 40.3 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO27840.1 - 3.6e-09 36.9 0.0 9.8e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO27840.1 - 3.7e-08 33.2 0.0 7.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGO27840.1 - 2.9e-05 24.8 0.0 0.00036 21.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGO27840.1 - 0.0004 20.0 0.0 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EGO27840.1 - 0.00074 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGO27840.1 - 0.02 15.0 0.1 0.054 13.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EGO27840.1 - 0.058 13.1 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 MOZ/SAS family zinc_ribbon_11 PF11682.8 EGO27840.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon Acetyltransf_4 PF13420.7 EGO27840.1 - 0.18 11.9 0.0 0.59 10.3 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain ThrE PF06738.12 EGO27841.1 - 9.8e-46 156.1 7.2 9.8e-46 156.1 7.2 2.3 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGO27841.1 - 4.8e-06 26.7 8.4 4.8e-06 26.7 8.4 2.9 2 2 0 2 2 2 2 Threonine/Serine exporter, ThrE tRNA-synt_2d PF01409.20 EGO27842.1 - 1e-84 283.8 0.0 2.1e-83 279.6 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGO27842.1 - 5.4e-15 55.4 0.4 3e-14 53.0 0.1 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGO27842.1 - 5.5e-10 39.1 0.0 3.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EGO27842.1 - 0.0014 18.6 0.3 0.0029 17.6 0.3 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 EGO27842.1 - 0.0028 17.7 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EGO27842.1 - 0.0032 16.6 0.8 0.016 14.3 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Pex2_Pex12 PF04757.14 EGO27843.1 - 1.2e-33 116.6 9.0 1.6e-33 116.2 9.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EGO27843.1 - 0.00046 20.1 3.0 0.00046 20.1 3.0 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO27843.1 - 0.00094 19.0 1.3 0.0042 16.9 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO27843.1 - 0.0034 17.7 2.5 0.023 15.0 0.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGO27843.1 - 0.0035 17.4 0.9 0.0098 16.0 0.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGO27843.1 - 0.0066 16.5 1.8 0.0066 16.5 1.8 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO27843.1 - 0.0078 16.1 3.4 0.078 12.9 3.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 EGO27843.1 - 0.025 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RDD PF06271.12 EGO27843.1 - 0.03 14.5 0.1 0.066 13.4 0.1 1.5 1 0 0 1 1 1 0 RDD family zf-rbx1 PF12678.7 EGO27843.1 - 0.034 14.4 0.6 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO27843.1 - 0.068 13.1 2.0 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGO27843.1 - 0.55 10.1 7.2 4 7.4 4.7 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3658 PF12395.8 EGO27844.1 - 0.052 13.4 0.0 0.079 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function Mur_ligase_M PF08245.12 EGO27845.1 - 3.3e-08 33.8 0.0 6.9e-05 22.9 0.0 2.4 1 1 1 2 2 2 2 Mur ligase middle domain DUF3239 PF11580.8 EGO27846.1 - 0.004 17.5 0.1 0.0044 17.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3239) PBP1_TM PF14812.6 EGO27847.1 - 0.051 13.9 0.5 0.099 13.0 0.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RGM_C PF06534.13 EGO27850.1 - 0.064 12.8 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Vps52 PF04129.12 EGO27851.1 - 1.4e-37 129.6 0.0 1.8e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGO27851.1 - 7.9e-06 24.6 2.3 3.8e-05 22.3 0.6 1.9 1 1 1 2 2 2 2 Exocyst complex component Sec3 MscS_porin PF12795.7 EGO27851.1 - 0.088 12.3 1.4 0.1 12.2 0.4 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Cep57_MT_bd PF06657.13 EGO27851.1 - 0.33 11.4 3.4 0.24 11.9 1.0 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Thioredoxin_12 PF18400.1 EGO27852.1 - 0.19 11.6 0.9 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Aldose_epim PF01263.20 EGO27853.1 - 3.2e-55 187.5 0.5 4.1e-55 187.2 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase JAB PF01398.21 EGO27855.1 - 2.2e-32 111.5 0.3 4.1e-32 110.6 0.3 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGO27855.1 - 5.1e-14 52.7 1.3 1.1e-13 51.6 1.3 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGO27855.1 - 1.6e-06 27.9 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 EGO27855.1 - 0.024 14.7 0.1 0.047 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) G6PD_bact PF10786.9 EGO27855.1 - 0.037 13.6 0.5 0.057 13.0 0.5 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) UPF0172 PF03665.13 EGO27855.1 - 0.047 13.7 1.3 0.094 12.8 0.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.20 EGO27856.1 - 4.6e-16 58.8 0.6 6.9e-16 58.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.25 EGO27857.1 - 4.6e-60 203.2 0.0 6.1e-41 140.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27857.1 - 7.8e-27 94.2 0.0 1.2e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EGO27857.1 - 6.2e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EGO27857.1 - 2.8e-08 33.4 0.2 0.00028 20.3 0.0 2.4 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 EGO27857.1 - 0.0012 18.5 0.1 0.74 9.4 0.0 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGO27857.1 - 0.002 18.1 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO27857.1 - 0.0072 15.3 0.3 0.017 14.1 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGO27857.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO27857.1 - 0.025 14.2 1.0 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 EGO27857.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.7 EGO27857.1 - 0.11 12.8 0.2 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 PAS domain SLAIN PF15301.6 EGO27858.1 - 0.0036 16.6 3.7 0.0038 16.5 3.7 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family VIR_N PF15912.5 EGO27859.1 - 0.54 9.8 3.9 0.96 9.0 3.9 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal THOC7 PF05615.13 EGO27860.1 - 8.6e-37 126.4 4.0 8.6e-37 126.4 4.0 1.8 1 1 0 1 1 1 1 Tho complex subunit 7 Filament PF00038.21 EGO27860.1 - 0.00017 21.3 6.7 0.0003 20.5 6.7 1.3 1 0 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 EGO27860.1 - 0.00066 19.2 8.2 0.00066 19.2 8.2 1.5 2 0 0 2 2 2 1 Golgin subfamily A member 5 Phage_int_SAM_2 PF12834.7 EGO27860.1 - 0.057 14.1 0.6 10 6.9 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal PIN_8 PF18476.1 EGO27860.1 - 0.07 13.0 1.5 0.16 11.8 1.5 1.5 1 0 0 1 1 1 0 PIN like domain FapA PF03961.13 EGO27860.1 - 0.1 11.2 3.2 0.16 10.5 3.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EGO27860.1 - 0.11 12.6 1.6 0.83 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4515 PF14988.6 EGO27860.1 - 0.15 11.9 9.9 0.25 11.1 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Atg14 PF10186.9 EGO27860.1 - 0.17 10.9 3.1 0.27 10.3 3.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 EGO27860.1 - 0.33 11.4 3.1 17 5.9 0.3 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.13 EGO27860.1 - 0.34 11.4 9.1 1.6 9.2 0.3 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fungal_TACC PF12709.7 EGO27860.1 - 0.35 11.4 4.6 0.37 11.3 1.0 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TolA_bind_tri PF16331.5 EGO27860.1 - 0.36 10.9 10.6 0.32 11.1 4.5 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation CCDC-167 PF15188.6 EGO27860.1 - 0.37 11.1 11.6 0.25 11.7 5.9 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF842 PF05811.13 EGO27860.1 - 0.39 10.4 5.9 0.083 12.6 1.0 2.3 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Cortex-I_coil PF09304.10 EGO27860.1 - 1.1 9.5 9.7 12 6.1 6.0 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4140 PF13600.6 EGO27860.1 - 3.8 8.0 8.3 9.7e+02 0.3 8.1 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HAUS6_N PF14661.6 EGO27860.1 - 4.3 6.9 8.1 13 5.2 8.3 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF724 PF05266.14 EGO27860.1 - 4.4 7.1 9.8 11 5.8 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EGO27860.1 - 6.8 4.5 8.7 0.13 10.2 1.7 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Lactamase_B_2 PF12706.7 EGO27861.1 - 1.7e-11 44.0 0.0 0.00047 19.7 0.0 3.1 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGO27861.1 - 7.9e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EGO27861.1 - 8.5e-07 29.2 0.2 1.5e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ChaC PF04752.12 EGO27861.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein PDEase_II PF02112.15 EGO27861.1 - 0.038 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II TolA_bind_tri PF16331.5 EGO27862.1 - 0.00079 19.5 4.7 0.00079 19.5 4.7 3.1 1 1 2 3 3 3 1 TolA binding protein trimerisation Apt1 PF10351.9 EGO27862.1 - 0.0037 16.2 5.9 0.0037 16.2 5.9 1.3 1 1 0 1 1 1 1 Golgi-body localisation protein domain DivIC PF04977.15 EGO27862.1 - 0.015 15.0 6.5 0.019 14.7 0.5 2.5 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 EGO27862.1 - 0.063 13.4 2.7 0.75 9.9 0.5 2.8 2 1 0 2 2 2 0 bZIP transcription factor SOGA PF11365.8 EGO27862.1 - 0.084 14.0 0.3 0.084 14.0 0.3 2.5 1 1 2 3 3 3 0 Protein SOGA FemAB PF02388.16 EGO27862.1 - 0.1 11.5 0.5 0.14 11.0 0.5 1.1 1 0 0 1 1 1 0 FemAB family Laminin_II PF06009.12 EGO27862.1 - 0.14 12.1 3.1 0.26 11.3 3.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Syntaxin-6_N PF09177.11 EGO27862.1 - 0.16 12.6 6.7 0.6 10.7 1.3 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DMPK_coil PF08826.10 EGO27862.1 - 0.26 11.4 5.0 0.27 11.4 1.7 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like Cnn_1N PF07989.11 EGO27862.1 - 0.78 9.9 5.9 2.8 8.2 4.1 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 EGO27862.1 - 0.95 8.8 4.4 1.3 8.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMP24_GP25L PF01105.24 EGO27862.1 - 1.1 9.1 5.1 0.5 10.3 0.6 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Spot_14 PF07084.12 EGO27862.1 - 1.2 9.3 5.4 0.31 11.2 0.2 2.4 2 1 1 3 3 3 0 Thyroid hormone-inducible hepatic protein Spot 14 zf-RING_11 PF17123.5 EGO27862.1 - 1.3 8.8 4.1 2.5 7.9 4.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger TMPIT PF07851.13 EGO27862.1 - 1.3 8.2 4.4 1.8 7.8 4.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2205 PF10224.9 EGO27862.1 - 1.6 8.8 6.9 0.4 10.7 1.1 2.5 1 1 1 2 2 2 0 Short coiled-coil protein ZapB PF06005.12 EGO27862.1 - 1.7 9.2 9.0 15 6.1 9.0 2.4 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 EGO27862.1 - 3.5 8.3 6.3 1.2 9.8 0.8 2.7 1 1 2 3 3 3 0 SlyX YabA PF06156.13 EGO27862.1 - 6.2 7.5 9.3 1.9 9.2 4.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 EGO27862.1 - 7.1 6.9 9.8 2.2 8.6 6.0 2.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RhoGEF PF00621.20 EGO27863.1 - 4.7e-20 72.6 0.6 1.9e-17 64.1 0.6 3.3 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 EGO27863.1 - 0.016 15.7 0.0 0.045 14.3 0.0 1.8 1 0 0 1 1 1 0 PH domain LRR_6 PF13516.6 EGO27864.1 - 5.4e-12 44.8 10.1 0.39 10.9 0.0 8.3 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 EGO27864.1 - 7.4e-12 45.3 5.9 0.17 12.4 0.0 6.4 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO27864.1 - 7.6e-09 34.9 3.7 4.5 8.2 0.5 7.2 6 1 0 6 6 6 3 Leucine Rich Repeat Amidohydro_3 PF07969.11 EGO27865.1 - 5.2e-13 49.3 4.4 2.9e-07 30.4 0.1 3.3 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO27865.1 - 5.3e-11 42.4 0.0 4e-07 29.7 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Myb_DNA-binding PF00249.31 EGO27866.1 - 1.6e-20 73.0 7.5 1.7e-10 41.0 0.1 3.4 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO27866.1 - 9.1e-15 54.7 6.0 1.6e-06 28.2 0.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain MbeD_MobD PF04899.12 EGO27866.1 - 0.07 13.2 0.2 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 MbeD/MobD like DUF2052 PF09747.9 EGO27867.1 - 6.4e-12 46.0 11.6 9.3e-12 45.5 11.6 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF676 PF05057.14 EGO27869.1 - 3.7e-07 29.9 0.0 8.5e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGO27869.1 - 1.6e-05 25.6 0.6 5.1e-05 24.0 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGO27869.1 - 0.00032 20.6 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGO27869.1 - 0.0016 17.7 0.1 0.0095 15.2 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGO27869.1 - 0.0021 17.9 0.0 0.0051 16.6 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 EGO27869.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EGO27869.1 - 0.0067 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 EGO27869.1 - 0.034 13.3 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 EGO27869.1 - 0.036 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 EGO27869.1 - 0.056 12.9 0.0 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 EGO27869.1 - 0.09 12.1 0.0 6.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) F-box-like PF12937.7 EGO27870.1 - 1.4e-12 47.3 3.6 4.2e-12 45.8 3.6 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGO27870.1 - 7.1e-08 32.6 15.8 0.25 11.8 0.0 7.5 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 EGO27870.1 - 0.0089 15.9 2.4 0.0089 15.9 2.4 3.7 3 0 0 3 3 3 1 F-box domain F-box_5 PF18511.1 EGO27870.1 - 0.091 12.3 0.0 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 F-box LRR_6 PF13516.6 EGO27870.1 - 4.4 7.6 23.7 19 5.7 0.0 9.2 11 0 0 11 11 11 0 Leucine Rich repeat LSM PF01423.22 EGO27871.1 - 7.3e-20 70.4 0.1 8.5e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain CAMSAP_CC1 PF17095.5 EGO27871.1 - 0.029 14.2 0.2 0.04 13.8 0.2 1.2 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF150_C PF17384.2 EGO27871.1 - 0.053 13.7 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Peptidase_S58 PF03576.14 EGO27871.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S58 2OG-FeII_Oxy_3 PF13640.6 EGO27872.1 - 1.8e-05 25.5 0.1 3.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF202 PF02656.15 EGO27873.1 - 3.3e-15 56.3 4.6 3.5e-15 56.2 2.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SANT_DAMP1_like PF16282.5 EGO27874.1 - 3e-33 113.8 9.6 5.5e-33 113.0 9.6 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EGO27874.1 - 1e-05 25.7 0.2 2.1e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO27874.1 - 0.0083 16.3 0.9 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DMAP1 PF05499.12 EGO27874.1 - 0.089 12.7 2.6 1.2 9.0 2.6 2.2 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) APG6_N PF17675.1 EGO27874.1 - 0.9 10.1 7.6 2.8 8.5 7.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region AAA PF00004.29 EGO27875.1 - 3.9e-22 79.1 0.0 5.7e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO27875.1 - 0.023 15.1 0.2 2.9 8.2 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 EGO27875.1 - 0.082 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO27875.1 - 0.11 12.8 0.3 1.5 9.1 0.3 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGO27875.1 - 0.12 12.3 0.3 0.42 10.5 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGO27875.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGO27875.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 EGO27877.1 - 4.7e-70 236.0 0.0 6.6e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27877.1 - 3.4e-46 157.6 0.0 4.8e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO27877.1 - 0.00012 21.5 0.0 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGO27877.1 - 0.00042 19.2 0.1 0.0013 17.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF1241 PF06840.11 EGO27877.1 - 0.031 13.9 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Sars6 PF12133.8 EGO27877.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus APH PF01636.23 EGO27877.1 - 0.14 12.0 0.0 9.2 6.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L29 PF00831.23 EGO27879.1 - 7.4e-19 67.5 0.9 7.4e-19 67.5 0.9 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein VirB8 PF04335.13 EGO27879.1 - 0.067 13.0 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein TolA_bind_tri PF16331.5 EGO27879.1 - 0.12 12.5 2.6 0.98 9.5 0.2 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation MRP-L47 PF06984.13 EGO27879.1 - 0.31 11.2 3.7 0.45 10.6 2.2 2.0 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) His_biosynth PF00977.21 EGO27880.1 - 3.5e-34 118.3 0.0 2.6e-33 115.4 0.0 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGO27880.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Fe-ADH PF00465.19 EGO27881.1 - 9.3e-89 297.8 0.0 1.3e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGO27881.1 - 3.3e-11 43.4 0.0 6.5e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DSBA PF01323.20 EGO27881.1 - 0.058 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Asp PF00026.23 EGO27882.1 - 1.5e-33 116.6 0.7 7.6e-32 111.0 0.7 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO27882.1 - 3.8e-05 24.0 3.8 0.0029 17.8 0.0 3.7 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal DUF1180 PF06679.12 EGO27882.1 - 0.078 13.4 2.4 0.097 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 EGO27882.1 - 0.1 13.5 0.0 0.36 11.8 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PPR_2 PF13041.6 EGO27883.1 - 2.8e-13 49.8 2.6 1.8e-08 34.4 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 EGO27883.1 - 0.0015 18.6 3.3 1.1 9.6 0.1 4.0 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 EGO27883.1 - 0.0059 16.7 0.4 0.46 10.6 0.0 2.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain RPM2 PF08579.11 EGO27883.1 - 0.062 13.7 0.0 1.3 9.4 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Ribophorin_I PF04597.14 EGO27885.1 - 7.1e-134 447.3 1.2 8e-134 447.1 1.2 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.19 EGO27886.1 - 1.1e-21 77.0 0.4 1.1e-21 77.0 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e GILT PF03227.16 EGO27887.1 - 5.8e-15 55.5 0.3 1.1e-14 54.6 0.3 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Cid2 PF09774.9 EGO27888.1 - 1.2e-29 103.8 5.4 2.1e-29 103.0 5.4 1.4 1 0 0 1 1 1 1 Caffeine-induced death protein 2 zf-H2C2_2 PF13465.6 EGO27889.1 - 6.9e-06 26.3 12.5 0.0042 17.5 0.9 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO27889.1 - 0.00015 22.3 13.0 0.066 14.1 0.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO27889.1 - 0.0018 18.6 13.8 0.023 15.1 0.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 EGO27889.1 - 0.04 14.2 1.6 0.094 13.0 1.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EGO27889.1 - 0.071 13.5 0.9 0.23 11.9 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 EGO27889.1 - 0.92 10.2 4.9 3.3 8.5 1.6 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger MFS_1 PF07690.16 EGO27894.1 - 4.4e-18 65.3 5.5 5.8e-18 64.9 5.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO27894.1 - 1.2e-05 24.4 1.4 1.6e-05 24.0 1.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter GCP_N_terminal PF17681.1 EGO27895.1 - 9.5e-99 330.9 0.0 2.2e-98 329.7 0.0 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGO27895.1 - 6.5e-92 308.3 2.5 6.5e-92 308.3 2.5 2.2 3 1 1 4 4 4 1 Gamma tubulin complex component C-terminal E1-E2_ATPase PF00122.20 EGO27896.1 - 7.7e-45 152.6 1.1 7.7e-45 152.6 1.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGO27896.1 - 3e-36 125.7 0.0 1.1e-35 123.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGO27896.1 - 1.1e-14 54.7 3.2 2.7e-08 34.1 1.5 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.7 EGO27896.1 - 2.1e-06 28.3 0.0 4.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGO27896.1 - 0.0027 17.5 0.1 0.0071 16.1 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spore_YhcN_YlaJ PF09580.10 EGO27896.1 - 0.16 12.0 0.7 0.92 9.6 0.3 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) His_Phos_2 PF00328.22 EGO27897.1 - 1.2e-85 288.1 0.0 2.6e-85 287.1 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EGO27897.1 - 2e-33 114.4 0.3 5e-33 113.1 0.0 1.9 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGO27897.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Exo_endo_phos PF03372.23 EGO27898.1 - 1.5e-17 63.9 0.2 2.1e-17 63.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 EGO27899.1 - 8.3e-05 22.5 31.4 0.024 14.7 1.9 3.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 EGO27899.1 - 1.6 8.8 15.9 0.96 9.5 0.8 3.6 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO27899.1 - 3.5 7.4 25.8 0.39 10.5 1.5 4.1 3 1 1 4 4 4 0 Zinc knuckle ABC_tran PF00005.27 EGO27900.1 - 2e-17 64.0 0.0 6.5e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO27900.1 - 1.5e-11 44.7 0.5 6.7e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGO27900.1 - 0.00018 21.1 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGO27900.1 - 0.00095 18.9 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGO27900.1 - 0.0028 17.6 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EGO27900.1 - 0.0037 17.0 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGO27900.1 - 0.013 16.1 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGO27900.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 EGO27900.1 - 0.022 14.2 0.4 0.65 9.4 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGO27900.1 - 0.039 14.2 0.2 0.096 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGO27900.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 EGO27900.1 - 0.048 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EGO27900.1 - 0.12 12.6 0.2 0.32 11.3 0.1 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO27900.1 - 0.13 12.2 0.3 0.31 10.9 0.2 1.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EGO27900.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Opy2 PF09463.10 EGO27901.1 - 1.4e-06 28.5 20.1 2.4e-06 27.8 20.1 1.4 1 0 0 1 1 1 1 Opy2 protein VSP PF03302.13 EGO27901.1 - 0.00022 20.2 5.8 0.00036 19.5 5.8 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 EGO27901.1 - 0.057 13.2 3.4 0.71 9.7 0.8 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 PTPS_related PF10131.9 EGO27901.1 - 0.087 11.1 0.4 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF4381 PF14316.6 EGO27901.1 - 0.099 12.9 1.1 0.23 11.7 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PTP_tm PF18861.1 EGO27901.1 - 0.1 12.6 0.4 0.3 11.1 0.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Tad PF13400.6 EGO27901.1 - 0.35 11.2 8.5 0.15 12.4 5.4 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like UQ_con PF00179.26 EGO27902.1 - 9.4e-21 73.9 0.0 1.9e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 EGO27902.1 - 0.00024 21.2 5.0 0.00059 20.0 5.0 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain UBA PF00627.31 EGO27902.1 - 0.008 16.1 0.1 0.024 14.5 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Mito_carr PF00153.27 EGO27903.1 - 3.7e-51 171.0 2.6 2.6e-16 59.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 EGO27903.1 - 0.001 19.1 0.3 0.73 10.0 0.1 2.5 2 0 0 2 2 2 2 PrcB C-terminal GTP_EFTU PF00009.27 EGO27904.1 - 4.1e-46 157.0 0.0 5.6e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO27904.1 - 9.8e-36 122.5 0.1 7.7e-35 119.6 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGO27904.1 - 2.9e-07 30.8 0.1 7.5e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO27904.1 - 0.00043 20.3 0.1 0.0023 18.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO27904.1 - 0.046 13.1 0.0 0.69 9.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Sec7 PF01369.20 EGO27905.1 - 1.1e-70 237.1 0.0 2.8e-70 235.7 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGO27905.1 - 3.9e-46 156.8 3.7 3.9e-46 156.8 3.7 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGO27905.1 - 3.6e-34 116.5 9.3 2.2e-33 113.9 0.1 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGO27905.1 - 1.1e-22 80.6 0.2 6.3e-20 71.6 0.0 3.3 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DS PF01916.17 EGO27906.1 - 1.2e-134 448.1 0.0 1.4e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.20 EGO27907.1 - 1.1e-77 260.6 1.0 1.2e-77 260.4 1.0 1.0 1 0 0 1 1 1 1 14-3-3 protein HPP PF04982.13 EGO27908.1 - 8.5e-43 145.4 11.5 1.2e-42 144.9 9.7 1.9 2 0 0 2 2 2 1 HPP family Phage_holin_5_2 PF16079.5 EGO27908.1 - 0.29 11.5 8.9 2.6 8.4 3.9 3.2 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF4064 PF13273.6 EGO27908.1 - 0.5 10.7 3.1 1.1 9.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Aminotran_1_2 PF00155.21 EGO27909.1 - 1.4e-09 37.6 0.0 4.8e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Polyketide_cyc PF03364.20 EGO27911.1 - 1.3e-23 83.6 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Chitin_synth_1 PF01644.17 EGO27912.1 - 7.2e-68 227.7 0.1 1.1e-67 227.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO27912.1 - 1e-28 99.1 0.2 2.2e-28 98.0 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO27912.1 - 2.8e-22 79.1 0.3 1.1e-17 63.9 0.1 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO27912.1 - 9.7e-07 28.9 6.7 8.2e-06 25.9 6.5 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Spo12 PF05032.12 EGO27913.1 - 1.2e-11 44.2 1.6 1.9e-11 43.6 0.1 2.1 2 0 0 2 2 2 1 Spo12 family Mannosidase_ig PF17786.1 EGO27915.1 - 5.1e-17 62.3 0.2 1.7e-16 60.6 0.1 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EGO27915.1 - 3.9e-09 37.2 0.3 1.1e-08 35.7 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EGO27915.1 - 0.00015 21.7 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 EGO27915.1 - 0.00033 20.3 0.0 0.0014 18.3 0.0 2.1 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EGO27915.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.16 EGO27916.1 - 4.3e-36 124.6 34.9 4.3e-36 124.6 34.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA_SAD PF07973.14 EGO27917.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EGO27917.1 - 0.022 13.3 0.5 0.037 12.5 0.5 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) DHHA1 PF02272.19 EGO27917.1 - 0.19 12.1 1.9 0.77 10.2 1.9 2.0 1 1 0 1 1 1 0 DHHA1 domain Prok-RING_4 PF14447.6 EGO27918.1 - 4.6e-07 29.6 3.2 1e-05 25.3 0.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO27918.1 - 2.3e-06 27.4 0.1 4.8e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO27918.1 - 8.7e-06 26.0 7.1 0.00011 22.5 7.1 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO27918.1 - 1.8e-05 24.5 1.6 0.00042 20.1 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO27918.1 - 1.9e-05 24.5 1.4 6e-05 22.9 1.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO27918.1 - 3.1e-05 23.9 0.9 0.00018 21.5 0.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO27918.1 - 4.9e-05 23.1 4.8 0.00029 20.6 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO27918.1 - 0.00037 20.7 3.3 0.00091 19.5 3.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO27918.1 - 0.00062 19.8 1.1 0.0015 18.6 1.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO27918.1 - 0.0012 18.6 0.8 0.0096 15.7 0.2 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGO27918.1 - 0.069 13.3 5.4 0.1 12.8 1.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING UBZ_FAAP20 PF15750.5 EGO27918.1 - 0.12 12.3 5.8 2.4 8.2 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Rubredoxin PF00301.20 EGO27918.1 - 0.25 11.4 1.4 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin zf-Nse PF11789.8 EGO27918.1 - 0.5 10.2 2.4 1.1 9.1 1.4 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGO27918.1 - 4.6 7.1 8.1 17 5.3 0.0 3.4 3 1 0 3 3 3 0 RING-like zinc finger MFS_1 PF07690.16 EGO27919.1 - 2.3e-39 135.3 35.5 1.9e-37 129.0 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NIF PF03031.18 EGO27920.1 - 6.2e-53 178.7 0.0 8.6e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SLD3 PF08639.10 EGO27923.1 - 6.5e-13 48.3 7.0 3.4e-12 45.9 3.9 2.5 1 1 1 2 2 2 1 DNA replication regulator SLD3 DEAD PF00270.29 EGO27924.1 - 3.8e-48 163.6 0.0 6.2e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO27924.1 - 1.5e-30 105.8 0.0 5.2e-30 104.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO27924.1 - 8.2e-06 25.9 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO27924.1 - 0.00038 19.8 0.1 0.001 18.3 0.0 1.6 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 EGO27924.1 - 0.00065 19.5 0.0 0.0037 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain RTA1 PF04479.13 EGO27925.1 - 1.4e-18 67.3 1.0 1.4e-18 67.2 1.0 1.0 1 0 0 1 1 1 1 RTA1 like protein Yip1 PF04893.17 EGO27925.1 - 0.01 15.5 2.2 0.012 15.3 2.2 1.0 1 0 0 1 1 1 0 Yip1 domain Zn_clus PF00172.18 EGO27926.1 - 0.00016 21.7 11.8 0.00016 21.7 11.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg29_N PF18388.1 EGO27927.1 - 2.1e-15 56.3 0.1 5.1e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 Atg29 N-terminal domain Rab15_effector PF15208.6 EGO27927.1 - 0.24 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Rab15 effector zf-CpG_bind_C PF12269.8 EGO27927.1 - 0.31 10.8 0.7 0.49 10.1 0.7 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain TFIID-18kDa PF02269.16 EGO27928.1 - 9.3e-32 108.9 0.1 1.9e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 EGO27928.1 - 0.0024 18.2 1.5 0.0051 17.1 1.5 1.6 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha PAPS_reduct PF01507.19 EGO27929.1 - 7e-38 130.4 0.0 9e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonucleas_3_3 PF14622.6 EGO27930.1 - 4.2e-17 62.5 0.0 6.3e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGO27930.1 - 8e-14 52.1 0.0 2.4e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EGO27930.1 - 5.7e-09 36.6 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif LPP20 PF02169.16 EGO27930.1 - 0.082 13.3 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 LPP20 lipoprotein Coiled-coil_56 PF09813.9 EGO27931.1 - 6.3e-07 29.4 0.0 8.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 FixS PF03597.15 EGO27931.1 - 0.14 11.9 0.5 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type COX7a PF02238.15 EGO27932.1 - 4.2e-20 71.9 2.5 4.8e-20 71.7 2.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII PI3_PI4_kinase PF00454.27 EGO27933.1 - 1.2e-49 169.4 0.0 2.4e-49 168.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EGO27933.1 - 1.3e-29 102.1 0.0 2.3e-28 98.1 0.0 3.3 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 EGO27933.1 - 6.2e-28 98.0 0.7 1e-21 77.6 0.1 2.6 1 1 1 2 2 2 2 FAT domain FATC PF02260.20 EGO27933.1 - 4.7e-11 42.3 0.2 2.1e-10 40.2 0.2 2.2 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 EGO27933.1 - 0.12 12.9 0.0 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat GATA PF00320.27 EGO27938.1 - 3.2e-08 33.0 4.2 6.2e-08 32.1 4.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Polo_box_3 PF18544.1 EGO27943.1 - 0.072 13.7 0.0 0.085 13.5 0.0 1.2 1 0 0 1 1 1 0 Polo box domain PHD PF00628.29 EGO27944.1 - 5.2e-05 23.1 5.1 7.5e-05 22.5 5.1 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGO27944.1 - 0.088 13.1 0.5 0.088 13.1 0.5 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain TPR_4 PF07721.14 EGO27944.1 - 0.48 11.2 4.8 7.3 7.5 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_holin_4_2 PF04020.13 EGO27947.1 - 0.03 15.0 0.6 0.033 14.9 0.6 1.1 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV Rhomboid PF01694.22 EGO27949.1 - 5.3e-07 29.7 7.4 7.9e-07 29.2 7.4 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EGO27949.1 - 0.0036 17.8 1.7 0.0052 17.3 0.7 1.8 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) eIF-3_zeta PF05091.12 EGO27950.1 - 2.1e-212 706.7 0.0 2.4e-212 706.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 EGO27951.1 - 7.2e-18 64.2 0.1 1.1e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO27951.1 - 3.2e-06 27.2 0.0 7.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EGO27951.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.12 EGO27951.1 - 0.95 9.2 8.3 1.3 8.8 8.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 EGO27951.1 - 3.4 7.1 5.9 4.7 6.7 5.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 EGO27951.1 - 8.8 6.0 6.0 15 5.3 6.0 1.4 1 0 0 1 1 1 0 Connexin HSCB_C PF07743.13 EGO27952.1 - 8e-16 58.3 4.7 8e-16 58.3 4.7 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGO27952.1 - 2.1e-05 24.5 0.0 5.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 EGO27952.1 - 0.026 14.5 1.5 0.05 13.6 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 EGO27952.1 - 0.088 12.9 5.0 0.18 11.9 5.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 EGO27952.1 - 0.54 9.7 8.3 1.1 8.7 8.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 EGO27952.1 - 2.9 7.5 8.9 0.29 10.7 1.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger Prenyltrans PF00432.21 EGO27953.1 - 4.3e-57 189.5 10.1 8.2e-13 47.9 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGO27953.1 - 0.00013 21.2 0.0 0.086 11.9 0.0 3.6 2 1 1 4 4 4 1 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGO27953.1 - 0.0075 15.4 0.0 0.024 13.7 0.0 1.8 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Rhodanese PF00581.20 EGO27954.1 - 2.7e-09 37.5 0.0 2.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain APH PF01636.23 EGO27958.1 - 0.0011 18.9 0.4 0.013 15.4 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGO27958.1 - 0.0035 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 EGO27958.1 - 0.0059 16.3 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EGO27958.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGO27958.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EGO27958.1 - 0.054 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 EGO27958.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHC_3 PF13917.6 EGO27962.1 - 7.7e-07 29.0 1.5 8e-07 28.9 1.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO27962.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO27962.1 - 0.01 15.3 0.7 0.016 14.6 0.7 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO27962.1 - 0.15 11.8 3.5 0.19 11.4 3.5 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 EGO27963.1 - 1e-07 32.1 0.3 1e-07 32.1 0.3 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO27963.1 - 3.1e-06 27.0 3.4 6e-06 26.1 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO27963.1 - 0.011 15.7 2.3 0.011 15.7 2.3 2.0 2 0 0 2 2 2 0 Zinc knuckle Sec_GG PF07549.14 EGO27966.1 - 0.064 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-CCHC PF00098.23 EGO27967.1 - 2.5e-08 33.6 3.7 4.6e-08 32.8 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF5637 PF18687.1 EGO27967.1 - 0.11 12.5 3.5 0.23 11.5 3.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5637) Pkinase PF00069.25 EGO27968.1 - 2.3e-07 30.5 0.0 1.3e-05 24.7 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO27968.1 - 0.028 13.7 0.0 0.067 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase adh_short PF00106.25 EGO27969.1 - 2.6e-41 141.3 0.4 3.8e-41 140.7 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO27969.1 - 1.5e-39 135.9 0.3 3.1e-39 134.9 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO27969.1 - 1.7e-12 47.7 1.0 5.6e-12 45.9 1.0 1.9 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.27 EGO27969.1 - 0.00053 20.5 0.1 0.007 16.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 EGO27969.1 - 0.004 16.6 0.3 0.022 14.2 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO27969.1 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EGO27969.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 EGO27969.1 - 0.012 15.5 0.4 0.03 14.2 0.2 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 EGO27969.1 - 0.029 14.3 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus RmlD_sub_bind PF04321.17 EGO27969.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox_2 PF07992.14 EGO27969.1 - 0.053 12.7 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 EGO27969.1 - 0.088 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2353 PF09789.9 EGO27970.1 - 0.0034 16.8 26.1 0.03 13.7 9.3 2.5 2 1 0 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.9 EGO27970.1 - 0.22 10.6 24.5 0.12 11.4 18.2 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EGO27970.1 - 3.3 7.2 10.9 8.3 5.9 10.9 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1192 PF06698.11 EGO27970.1 - 8.5 6.5 7.8 0.67 10.1 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) RasGAP PF00616.19 EGO27971.1 - 3.4e-21 75.9 0.0 1.7e-13 50.7 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGO27971.1 - 1e-09 38.7 0.1 2.8e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 EGO27971.1 - 9.2e-06 25.7 0.1 3.8e-05 23.7 0.1 2.2 1 0 0 1 1 1 1 Cell morphogenesis C-terminal RRM_1 PF00076.22 EGO27972.1 - 1.1e-31 108.4 0.0 3.1e-16 58.9 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO27972.1 - 1.9e-05 24.6 0.0 7.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EGO27972.1 - 0.0016 18.4 0.0 0.0044 17.0 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGO27972.1 - 0.026 14.7 0.0 0.82 9.8 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif RRM_5 PF13893.6 EGO27972.1 - 0.039 13.6 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BH3 PF15285.6 EGO27972.1 - 0.07 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Band_7 PF01145.25 EGO27973.1 - 1.2e-23 84.1 5.1 2e-23 83.3 5.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family EVE PF01878.18 EGO27974.1 - 1.4e-23 83.5 0.0 3.6e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 EVE domain Zip PF02535.22 EGO27974.1 - 1.4 8.1 4.2 1.7 7.8 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_60s PF00428.19 EGO27974.1 - 2.4 8.8 9.4 1.7 9.3 7.5 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein RR_TM4-6 PF06459.12 EGO27974.1 - 6.3 6.5 11.0 8.8 6.1 11.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EGO27974.1 - 8.4 5.0 7.0 11 4.7 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Acyltransferase PF01553.21 EGO27975.1 - 7.8e-29 100.0 0.0 1.1e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GDPD PF03009.17 EGO27976.1 - 1.4e-30 106.9 0.0 1.8e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGO27976.1 - 1.1e-05 25.7 0.8 1.1e-05 25.7 0.8 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Na_H_Exchanger PF00999.21 EGO27980.1 - 2.6e-46 158.2 46.5 4.4e-46 157.4 46.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.17 EGO27981.1 - 9.3e-68 226.6 6.8 1e-67 226.4 6.8 1.0 1 0 0 1 1 1 1 G10 protein SDA1 PF05285.12 EGO27982.1 - 0.015 14.7 12.0 0.019 14.4 12.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGO27982.1 - 4.7 5.3 15.4 6.3 4.9 15.4 1.1 1 0 0 1 1 1 0 Nop14-like family Lip_prot_lig_C PF10437.9 EGO27983.1 - 2.8e-05 24.0 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus CX9C PF16860.5 EGO27984.1 - 0.00033 20.6 11.3 0.0093 16.0 4.4 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PBP_GOBP PF01395.22 EGO27984.1 - 0.0019 18.3 0.5 0.0019 18.3 0.5 1.5 2 0 0 2 2 2 1 PBP/GOBP family CHCH PF06747.13 EGO27984.1 - 0.0022 18.0 3.9 0.0022 18.0 3.9 2.5 2 1 0 2 2 2 1 CHCH domain YqzH PF14164.6 EGO27984.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 YqzH-like protein Pet191_N PF10203.9 EGO27984.1 - 3 8.2 10.9 18 5.8 0.3 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 EGO27984.1 - 4.6 7.5 10.8 0.37 11.0 3.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb ubiquitin PF00240.23 EGO27985.1 - 0.16 11.7 1.1 0.32 10.8 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family MAS20 PF02064.15 EGO27986.1 - 5.5e-37 126.8 0.1 1.7e-36 125.2 0.1 1.9 1 0 0 1 1 1 1 MAS20 protein import receptor DUF498 PF04430.14 EGO27986.1 - 3.9e-35 120.2 0.0 1e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) SET PF00856.28 EGO27986.1 - 8.8e-13 49.0 0.0 6.1e-12 46.2 0.0 2.7 2 1 0 2 2 2 1 SET domain SAF PF08666.12 EGO27986.1 - 0.0014 19.2 0.4 1.3 9.8 0.1 2.6 2 0 0 2 2 2 2 SAF domain SMK-1 PF04802.15 EGO27987.1 - 1.1e-82 276.5 1.5 2.7e-82 275.2 1.5 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 EGO27987.1 - 0.018 15.0 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 WH1 domain zf-C2H2 PF00096.26 EGO27988.1 - 1.4e-07 31.5 9.3 0.00012 22.4 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO27988.1 - 5.2e-07 30.0 9.2 0.00092 19.9 0.5 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO27988.1 - 3.3e-06 27.2 1.8 0.00024 21.3 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGO27988.1 - 9.5e-06 25.5 3.0 0.006 16.6 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGO27988.1 - 1e-05 25.7 2.6 5.8e-05 23.3 0.7 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGO27988.1 - 1.5e-05 24.7 1.2 0.021 14.6 0.7 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 EGO27988.1 - 5.1e-05 23.5 0.2 6.9e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 EGO27988.1 - 9.5e-05 22.2 3.9 0.011 15.6 0.4 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 EGO27988.1 - 0.0003 21.0 3.7 0.0079 16.5 0.1 2.4 2 1 1 3 3 2 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EGO27988.1 - 0.00052 20.4 2.3 0.29 11.6 0.1 2.2 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger Sgf11 PF08209.11 EGO27988.1 - 0.0071 15.9 0.4 0.21 11.2 0.0 2.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2H2_9 PF16293.5 EGO27988.1 - 0.034 14.0 3.3 3.6 7.5 0.0 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 EGO27988.1 - 0.042 14.1 0.1 0.042 14.1 0.1 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EGO27988.1 - 0.044 14.2 10.4 0.63 10.6 0.2 2.8 3 0 0 3 3 2 0 Zinc-finger double domain C1_4 PF07975.12 EGO27988.1 - 0.045 14.0 0.7 0.091 13.0 0.7 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain Rad50_zn_hook PF04423.14 EGO27988.1 - 0.049 13.5 4.2 3.6 7.5 0.2 2.5 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-TFIIB PF13453.6 EGO27988.1 - 0.13 11.6 0.6 0.35 10.2 0.1 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 EGO27988.1 - 0.15 12.2 2.2 0.74 10.0 0.5 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 EGO27988.1 - 0.27 11.5 2.5 2.8 8.3 2.5 2.4 1 1 0 1 1 1 0 zinc-ribbon PHD PF00628.29 EGO27988.1 - 0.51 10.3 3.9 0.28 11.1 1.4 1.9 2 1 0 2 2 1 0 PHD-finger CNH PF00780.22 EGO27990.1 - 0.00055 19.6 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 2 CNH domain TRP PF06011.12 EGO27991.1 - 6.4e-26 91.0 23.9 3.3e-24 85.4 23.9 2.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 EGO27991.1 - 0.001 19.5 0.2 0.0018 18.7 0.2 1.4 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EGO27991.1 - 0.074 13.4 1.6 0.079 13.3 0.4 1.6 2 0 0 2 2 2 0 ML-like domain UPF0029 PF01205.19 EGO27992.1 - 8e-31 106.5 0.0 1.6e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGO27992.1 - 4.4e-05 23.7 0.0 8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain AvrL567-A PF11529.8 EGO27992.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A FAA_hydrolase PF01557.18 EGO27994.1 - 1.8e-56 191.3 0.0 2.3e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RNR_N PF08343.10 EGO27995.1 - 0.12 12.4 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal DDE_1 PF03184.19 EGO27996.1 - 4.1e-06 26.5 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO27996.1 - 0.013 15.2 1.4 0.016 14.9 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF2681 PF10883.8 EGO27996.1 - 0.46 10.9 2.8 1.1 9.7 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CDC45 PF02724.14 EGO27996.1 - 6.2 5.0 7.3 9 4.5 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Proteasome PF00227.26 EGO27997.1 - 1.5e-60 204.0 0.0 2.2e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO27997.1 - 2e-08 33.7 0.0 7.5e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DDE_1 PF03184.19 EGO28001.1 - 2.6e-07 30.5 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO28001.1 - 0.0012 18.6 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF2681 PF10883.8 EGO28001.1 - 0.29 11.6 1.6 0.79 10.2 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Pkinase PF00069.25 EGO28002.1 - 1.3e-06 28.0 0.0 1.7e-05 24.3 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28002.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RTBV_P46 PF06216.11 EGO28003.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Pkinase PF00069.25 EGO28004.1 - 0.00011 21.7 0.0 0.00082 18.8 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase PF00069.25 EGO28005.1 - 6.2e-07 29.0 0.0 3.5e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain T3SS_basalb_I PF17001.5 EGO28008.1 - 0.03 14.9 0.3 0.074 13.7 0.1 1.7 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF3943 PF13084.6 EGO28008.1 - 0.042 13.7 0.8 0.3 11.0 0.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3943) LysM PF01476.20 EGO28012.1 - 1.5e-16 60.2 0.1 2.8e-07 30.5 0.1 2.2 2 0 0 2 2 2 2 LysM domain NOC3p PF07540.11 EGO28013.1 - 0.16 12.4 0.1 0.44 11.0 0.1 1.8 2 1 0 2 2 2 0 Nucleolar complex-associated protein Ribosomal_L34 PF00468.17 EGO28015.1 - 0.11 12.5 0.7 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L34 DUF3159 PF11361.8 EGO28019.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) RAB3GAP2_C PF14656.6 EGO28019.1 - 0.14 10.3 0.1 0.2 9.8 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus bPH_3 PF14470.6 EGO28021.1 - 0.0005 20.4 0.0 0.00081 19.7 0.0 1.5 1 1 0 1 1 1 1 Bacterial PH domain GRAM PF02893.20 EGO28021.1 - 0.0069 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 EGO28021.1 - 0.007 16.5 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 SNAP PF14938.6 EGO28022.1 - 1.5e-105 352.7 17.7 1.7e-105 352.5 17.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EGO28022.1 - 9e-05 22.2 4.6 0.083 13.0 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat PspA_IM30 PF04012.12 EGO28022.1 - 0.015 14.9 4.8 0.67 9.5 4.0 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF410 PF04190.13 EGO28022.1 - 0.027 14.3 3.2 0.29 10.9 3.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF410) TPR_12 PF13424.6 EGO28022.1 - 0.076 13.3 14.2 2.3 8.6 1.1 4.3 1 1 3 4 4 4 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 EGO28022.1 - 0.11 11.6 6.2 0.84 8.7 6.2 2.3 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_10 PF13374.6 EGO28022.1 - 0.11 12.4 2.9 1.6 8.7 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO28022.1 - 0.35 10.6 3.0 1.1 9.0 0.2 3.0 3 0 0 3 3 3 0 TPR repeat Phage_tail_APC PF16778.5 EGO28022.1 - 1.1 9.2 3.4 2.7 7.9 0.6 2.4 1 1 1 2 2 2 0 Phage tail assembly chaperone protein TPR_6 PF13174.6 EGO28022.1 - 1.4 9.7 9.6 91 4.0 0.5 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 EGO28022.1 - 4.7 8.4 7.1 50 5.3 0.0 5.6 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat CAP PF00188.26 EGO28022.1 - 5.2 7.9 6.9 2.2 9.1 3.7 1.9 1 1 1 2 2 2 0 Cysteine-rich secretory protein family Pkinase PF00069.25 EGO28023.1 - 6.4e-42 143.7 0.0 1.3e-23 83.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28023.1 - 4e-13 49.2 0.0 8.2e-10 38.4 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGO28023.1 - 8.2e-05 22.6 0.6 0.00018 21.5 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGO28023.1 - 0.01 15.5 0.0 0.042 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 EGO28024.1 - 5.9e-32 111.2 0.0 8.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO28024.1 - 2e-08 34.2 0.0 1.8e-07 31.1 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DM PF00751.18 EGO28024.1 - 2.4 8.1 8.4 4.8 7.2 1.1 2.9 2 0 0 2 2 2 0 DM DNA binding domain DUF1992 PF09350.10 EGO28026.1 - 6.4e-21 74.3 1.3 1.3e-20 73.3 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) SbcD_C PF12320.8 EGO28026.1 - 0.042 14.1 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Aldedh PF00171.22 EGO28027.1 - 5.6e-101 338.3 0.0 6.8e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_isomerase PF00160.21 EGO28029.1 - 5.6e-38 130.7 0.0 8.2e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGO28029.1 - 2e-15 56.4 0.0 3.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGO28030.1 - 1.2e-30 105.1 8.2 3.8e-05 24.3 0.0 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO28030.1 - 5.2e-14 52.3 0.0 4.9e-05 23.5 0.0 4.5 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO28030.1 - 0.0026 17.2 0.0 1.1 8.5 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain Frtz PF11768.8 EGO28030.1 - 0.0065 14.8 0.0 0.086 11.1 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EGO28030.1 - 0.016 13.8 0.0 0.031 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 EGO28030.1 - 0.055 14.0 3.5 2.7 8.6 0.1 4.5 4 1 1 5 5 5 0 PQQ-like domain Ge1_WD40 PF16529.5 EGO28030.1 - 0.14 11.0 0.0 12 4.8 0.0 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATG22 PF11700.8 EGO28031.1 - 2.1e-110 369.6 20.3 2.4e-110 369.4 20.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGO28031.1 - 3.9e-15 55.6 31.4 3.5e-08 32.8 11.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily RRM_3 PF08777.11 EGO28033.1 - 0.0036 17.3 0.0 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 RNA binding motif DUF1768 PF08719.11 EGO28034.1 - 2.3e-20 73.5 0.0 2.9e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Takusan PF04822.13 EGO28034.1 - 0.049 13.5 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 Takusan SAP18 PF06487.12 EGO28035.1 - 1.2e-34 119.5 0.0 1.6e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Cu_amine_oxid PF01179.20 EGO28036.1 - 3.2e-131 438.0 0.0 4.1e-131 437.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EGO28036.1 - 5.2e-09 35.7 0.0 1.6e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EGO28036.1 - 0.00033 20.8 0.0 0.00061 20.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.24 EGO28037.1 - 1e-82 278.5 20.8 1.2e-82 278.2 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO28037.1 - 1e-25 90.4 31.9 1.6e-24 86.5 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO28037.1 - 3.4e-09 35.7 3.4 3.4e-09 35.7 3.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EGO28037.1 - 7.2e-07 28.1 5.1 7.2e-07 28.1 5.1 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DUF2065 PF09838.9 EGO28037.1 - 0.0061 16.5 0.2 0.24 11.4 0.0 2.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2065) MMPL PF03176.15 EGO28037.1 - 0.13 11.2 1.7 0.24 10.3 1.7 1.4 1 0 0 1 1 1 0 MMPL family OATP PF03137.20 EGO28037.1 - 0.18 10.1 9.4 2.2 6.5 0.9 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4149 PF13664.6 EGO28037.1 - 3.9 7.9 8.8 0.63 10.4 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Paramyxo_C PF01692.18 EGO28038.1 - 0.032 13.6 0.8 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C MFS_1 PF07690.16 EGO28039.1 - 2.7e-21 75.9 51.1 7.9e-11 41.5 27.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3925 PF13063.6 EGO28039.1 - 1.9 8.8 7.9 0.65 10.3 2.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3925) ubiquitin PF00240.23 EGO28040.1 - 4.9e-25 87.1 0.3 5.3e-25 87.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGO28040.1 - 4.1e-13 49.0 0.6 4.4e-13 48.8 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGO28040.1 - 3.2e-05 23.8 0.0 3.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EGO28040.1 - 0.00015 22.2 0.1 0.0003 21.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO28040.1 - 0.025 15.0 0.1 0.028 14.8 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4600 PF15372.6 EGO28040.1 - 0.12 12.8 0.1 0.14 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) 2OG-FeII_Oxy_2 PF13532.6 EGO28041.1 - 2.4e-14 54.0 0.0 2.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA PF00004.29 EGO28042.1 - 2.5e-06 28.0 0.1 4.8e-06 27.0 0.1 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps36_ESCRT-II PF11605.8 EGO28042.1 - 0.031 14.5 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 His_Phos_1 PF00300.22 EGO28043.1 - 2.8e-11 43.5 0.1 7.4e-11 42.1 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) STE3 PF02076.15 EGO28044.1 - 1.6e-106 355.8 16.7 1.6e-106 355.8 16.7 1.7 2 0 0 2 2 2 1 Pheromone A receptor PH PF00169.29 EGO28045.1 - 3e-12 47.0 0.2 9.2e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 PH domain CH PF00307.31 EGO28045.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4776 PF16003.5 EGO28045.1 - 0.51 9.3 7.3 0.73 8.8 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Thaumatin PF00314.17 EGO28052.1 - 4.4e-12 46.1 10.4 7e-12 45.4 10.4 1.4 1 0 0 1 1 1 1 Thaumatin family Xlink PF00193.17 EGO28052.1 - 0.081 13.3 0.3 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 Extracellular link domain zf-MYND PF01753.18 EGO28053.1 - 2.8e-11 43.3 14.2 5.4e-11 42.4 14.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO28053.1 - 1.2 9.5 11.5 11 6.5 11.5 2.2 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_1 PF00515.28 EGO28055.1 - 5.5e-09 35.5 0.4 0.075 12.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO28055.1 - 1.9e-06 27.6 2.8 0.65 10.3 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 EGO28055.1 - 5.1e-06 26.3 0.0 2.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.6 EGO28055.1 - 0.0029 17.9 5.6 0.053 13.8 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.31 EGO28055.1 - 0.027 14.6 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain TPR_16 PF13432.6 EGO28055.1 - 0.11 13.2 0.0 0.11 13.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGO28055.1 - 0.19 12.0 2.0 6.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EURL PF06937.11 EGO28055.1 - 0.22 10.9 1.5 0.41 10.0 1.5 1.4 1 0 0 1 1 1 0 EURL protein G6PD_C PF02781.16 EGO28056.1 - 0.062 12.5 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Methyltransf_3 PF01596.17 EGO28058.1 - 3.1e-39 134.4 0.1 3.9e-39 134.0 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGO28058.1 - 3e-15 57.1 0.0 5.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO28058.1 - 3.9e-10 39.7 0.0 5.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO28058.1 - 1.5e-08 35.2 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO28058.1 - 1.8e-08 34.4 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EGO28058.1 - 2.7e-08 34.3 0.0 6.8e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO28058.1 - 1.8e-05 24.2 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EGO28058.1 - 0.00067 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EGO28058.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EGO28058.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 EGO28058.1 - 0.058 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF4219 PF13961.6 EGO28059.1 - 0.0059 16.2 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) CDC50 PF03381.15 EGO28060.1 - 0.09 12.3 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-CCHC PF00098.23 EGO28062.1 - 1.4e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO28062.1 - 0.0083 15.9 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO28062.1 - 0.014 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain tRNA-synt_1g PF09334.11 EGO28063.1 - 1.1e-89 300.9 0.0 8.2e-46 156.5 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGO28063.1 - 1.9e-20 72.7 0.2 8.4e-10 37.5 0.0 3.7 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGO28063.1 - 4.1e-11 42.8 0.0 8.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Herpes_V23 PF01802.17 EGO28065.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Sugar_tr PF00083.24 EGO28066.1 - 7.3e-76 255.8 20.0 8.1e-76 255.7 16.5 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO28066.1 - 2.4e-26 92.5 30.1 2.7e-25 89.0 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EGO28066.1 - 0.0013 17.7 1.3 0.0027 16.7 0.2 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EGO28066.1 - 0.0041 15.6 2.7 0.0041 15.6 2.7 2.1 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3937 PF13073.6 EGO28066.1 - 0.062 13.4 1.3 0.17 12.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) FAD_binding_4 PF01565.23 EGO28067.1 - 1e-15 57.7 1.3 2.7e-15 56.3 1.3 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO28067.1 - 3.3e-09 36.7 0.1 7e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like zinc_ribbon_10 PF10058.9 EGO28068.1 - 1.8e-20 72.4 0.3 2.8e-20 71.8 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 EGO28068.1 - 0.041 13.8 0.7 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF459 PF04311.13 EGO28068.1 - 0.057 12.4 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF459) NOB1_Zn_bind PF08772.11 EGO28068.1 - 0.091 12.9 0.8 0.25 11.5 0.8 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 EGO28068.1 - 0.1 12.8 0.5 0.19 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EGO28068.1 - 0.18 11.8 1.6 0.29 11.1 0.8 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Hydrophobin PF01185.18 EGO28069.1 - 3.9e-25 88.3 9.0 4.6e-25 88.0 9.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin SapA PF02199.15 EGO28069.1 - 0.026 14.8 1.4 0.026 14.8 1.4 1.6 2 0 0 2 2 2 0 Saposin A-type domain ABC_tran PF00005.27 EGO28070.1 - 1.8e-46 158.0 0.0 1.7e-22 80.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGO28070.1 - 7.9e-20 70.7 3.9 7.9e-20 70.7 3.9 2.2 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 EGO28070.1 - 2.1e-14 54.0 4.7 0.0035 17.2 0.2 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO28070.1 - 4.3e-09 36.0 0.2 0.00041 20.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGO28070.1 - 9.2e-09 35.1 0.5 0.71 9.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO28070.1 - 1.4e-08 35.5 5.8 0.0043 17.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EGO28070.1 - 7.5e-08 32.9 0.0 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGO28070.1 - 6.7e-06 26.1 0.0 0.081 12.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 EGO28070.1 - 9.5e-06 25.5 11.2 0.095 12.4 1.1 4.9 2 2 2 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO28070.1 - 7.9e-05 22.6 0.6 0.16 11.9 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EGO28070.1 - 9.5e-05 22.5 0.1 0.2 11.8 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EGO28070.1 - 0.00012 22.6 0.0 0.72 10.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGO28070.1 - 0.00039 20.7 0.0 0.84 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGO28070.1 - 0.00096 18.9 0.1 1.9 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGO28070.1 - 0.001 19.4 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO28070.1 - 0.001 19.4 0.5 4.3 7.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_27 PF13514.6 EGO28070.1 - 0.0013 18.4 0.2 0.21 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 EGO28070.1 - 0.0048 17.0 7.7 0.73 9.9 0.3 4.2 4 2 1 5 5 4 2 Helicase HerA, central domain AAA_33 PF13671.6 EGO28070.1 - 0.0051 17.0 0.0 6.2 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EGO28070.1 - 0.0054 16.5 0.0 0.74 9.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EGO28070.1 - 0.007 15.7 0.1 2.4 7.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 EGO28070.1 - 0.0075 16.1 0.2 6.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EGO28070.1 - 0.013 15.4 2.1 1 9.3 0.0 3.1 4 0 0 4 4 3 0 NTPase Zeta_toxin PF06414.12 EGO28070.1 - 0.019 14.3 0.0 0.58 9.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Roc PF08477.13 EGO28070.1 - 0.021 15.1 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 EGO28070.1 - 0.021 15.2 0.4 11 6.5 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 EGO28070.1 - 0.028 14.4 0.0 6.8 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 EGO28070.1 - 0.03 13.8 0.8 5.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein NB-ARC PF00931.22 EGO28070.1 - 0.032 13.4 0.0 7.8 5.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 EGO28070.1 - 0.032 13.9 0.5 1.7 8.2 0.0 3.0 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 EGO28070.1 - 0.039 13.1 2.5 2.2 7.3 0.3 2.8 2 2 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EGO28070.1 - 0.04 14.3 0.0 19 5.7 0.0 4.1 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 EGO28070.1 - 0.041 13.7 0.0 3 7.6 0.0 3.2 3 0 0 3 3 3 0 MukB N-terminal PRK PF00485.18 EGO28070.1 - 0.041 13.6 0.0 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 EGO28070.1 - 0.08 12.4 0.4 1 8.8 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family MeaB PF03308.16 EGO28070.1 - 0.1 11.6 0.0 12 4.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EGO28070.1 - 0.1 12.6 0.6 13 5.8 0.0 3.2 3 1 1 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EGO28070.1 - 0.11 12.6 9.9 1.6 8.8 0.4 4.4 2 2 1 3 3 3 0 Dynamin family Thymidylate_kin PF02223.17 EGO28070.1 - 0.24 11.0 3.0 19 4.8 0.0 3.7 4 0 0 4 4 4 0 Thymidylate kinase Metallophos PF00149.28 EGO28071.1 - 2.7e-36 126.0 0.1 4.4e-36 125.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO28071.1 - 0.02 15.3 0.7 0.04 14.4 0.7 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EGO28071.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-C2H2 PF00096.26 EGO28073.1 - 9.1e-09 35.3 10.4 1.1e-06 28.7 2.5 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO28073.1 - 1e-06 28.9 9.2 2.3e-05 24.6 3.7 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO28073.1 - 0.00035 21.2 8.2 0.0011 19.6 1.2 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Dof PF02701.15 EGO28073.1 - 0.00097 19.2 1.2 0.00097 19.2 1.2 1.5 2 0 0 2 2 2 1 Dof domain, zinc finger zf-C2H2_11 PF16622.5 EGO28073.1 - 0.0045 16.7 1.5 0.0094 15.7 1.5 1.6 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-met PF12874.7 EGO28073.1 - 0.012 16.0 3.0 0.053 13.9 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO28073.1 - 0.014 15.6 0.4 0.032 14.5 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EGO28073.1 - 0.035 14.7 3.0 0.54 10.9 0.7 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EGO28073.1 - 0.93 9.6 7.2 0.52 10.4 2.8 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger DUF4552 PF15089.6 EGO28074.1 - 0.031 13.4 0.0 0.031 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Ribosomal_L1 PF00687.21 EGO28075.1 - 3.6e-45 154.2 1.4 4.2e-45 154.0 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family HTH_17 PF12728.7 EGO28076.1 - 0.097 12.9 0.1 0.48 10.7 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain Pescadillo_N PF06732.11 EGO28077.1 - 3.5e-123 410.5 0.1 7.2e-123 409.5 0.1 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGO28077.1 - 1.2e-09 38.4 0.0 3.9e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGO28077.1 - 3.4e-05 24.1 0.0 0.00013 22.3 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGO28077.1 - 0.00056 20.2 0.1 0.0024 18.1 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain p450 PF00067.22 EGO28078.1 - 6e-64 216.5 0.0 8.7e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLA2_B PF01735.18 EGO28079.1 - 1.9e-103 346.5 1.5 2.5e-103 346.1 1.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PCI PF01399.27 EGO28080.1 - 5.8e-13 49.3 0.0 1.4e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain STb_secrete PF09075.10 EGO28080.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory GCP_N_terminal PF17681.1 EGO28082.1 - 2.2e-35 122.8 0.3 4.7e-35 121.7 0.3 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGO28082.1 - 4.9e-26 91.9 0.9 4.9e-26 91.9 0.9 2.3 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Mgm101p PF06420.12 EGO28083.1 - 5.4e-88 292.9 0.0 6e-88 292.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Tyrosinase PF00264.20 EGO28084.1 - 3.3e-38 132.2 0.1 6.8e-38 131.2 0.1 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EGO28084.1 - 0.00034 21.3 0.0 0.00068 20.3 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain IBR PF01485.21 EGO28085.1 - 4.5e-17 62.0 20.8 1.3e-08 34.9 7.5 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain MAJIN PF15077.6 EGO28085.1 - 0.093 12.5 1.1 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein ABC_tran PF00005.27 EGO28089.1 - 4.1e-28 98.6 0.1 7.4e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EGO28089.1 - 0.0016 18.5 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO28089.1 - 0.0088 16.4 0.3 0.025 14.9 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGO28089.1 - 0.0089 15.8 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO28089.1 - 0.021 15.3 0.1 0.055 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGO28089.1 - 0.039 13.4 2.2 0.55 9.6 0.1 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGO28089.1 - 0.05 13.7 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 EGO28089.1 - 0.29 10.9 1.7 1.3 8.8 1.4 2.2 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ofd1_CTDD PF10637.9 EGO28090.1 - 4.6e-77 258.8 0.0 5.2e-73 245.5 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EGO28090.1 - 1.3e-29 102.7 0.0 4e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGO28090.1 - 7.5e-14 52.4 0.0 4.5e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Repressor_Mnt PF11423.8 EGO28092.1 - 0.0086 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Regulatory protein Mnt YL1 PF05764.13 EGO28095.1 - 0.011 15.9 11.8 0.011 15.9 11.8 1.4 2 0 0 2 2 2 0 YL1 nuclear protein SR-25 PF10500.9 EGO28095.1 - 0.016 14.8 11.1 0.028 14.1 11.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pes-10 PF07149.11 EGO28095.1 - 0.65 9.0 6.1 1 8.3 6.1 1.4 1 0 0 1 1 1 0 Pes-10 Cwf_Cwc_15 PF04889.12 EGO28095.1 - 1.8 8.2 16.6 0.16 11.7 12.2 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EGO28095.1 - 2 7.7 20.4 1.7 7.9 18.9 1.5 1 1 1 2 2 2 0 BUD22 CDC45 PF02724.14 EGO28095.1 - 6.7 4.9 12.6 9.4 4.4 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.17 EGO28098.1 - 1.7e-05 25.0 4.7 2e-05 24.7 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 EGO28099.1 - 0.00029 21.3 0.0 0.00044 20.8 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28099.1 - 0.00082 20.0 0.0 0.0012 19.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO28099.1 - 0.0019 18.0 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Siva PF05458.12 EGO28099.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF5475 PF17569.2 EGO28099.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5475) COesterase PF00135.28 EGO28102.1 - 1.4e-06 27.5 0.1 1.4e-06 27.5 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Repressor_Mnt PF11423.8 EGO28103.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 0 Regulatory protein Mnt HIG_1_N PF04588.13 EGO28104.1 - 0.0042 17.3 0.4 0.0099 16.1 0.4 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Presenilin PF01080.17 EGO28105.1 - 1 8.1 2.4 1.2 7.8 2.4 1.1 1 0 0 1 1 1 0 Presenilin Nucleoporin2 PF04096.14 EGO28107.1 - 6.7e-44 149.6 0.0 9.6e-44 149.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase RNA_pol_Rpb2_6 PF00562.28 EGO28108.1 - 8.6e-113 377.3 0.0 1.6e-112 376.4 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGO28108.1 - 4.2e-34 117.8 0.0 6.5e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGO28108.1 - 1.5e-27 95.6 0.0 3.4e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EGO28108.1 - 1.9e-25 88.6 0.0 5.5e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EGO28108.1 - 7.7e-22 77.9 0.0 1.7e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGO28108.1 - 4e-19 68.8 0.3 4.2e-15 55.9 0.2 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 FOXP-CC PF16159.5 EGO28110.1 - 0.018 15.7 2.1 3.9 8.2 0.1 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EGO28110.1 - 0.024 15.5 7.0 0.14 13.1 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 EGO28110.1 - 0.039 14.2 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_aberr PF17017.5 EGO28110.1 - 0.066 13.4 0.2 0.24 11.5 0.0 1.8 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 EGO28110.1 - 0.12 12.7 0.6 1.4 9.2 0.5 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 EGO28110.1 - 0.15 12.5 6.6 0.42 11.2 0.6 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Methyltransf_23 PF13489.6 EGO28111.1 - 4.7e-12 46.1 0.0 6.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO28111.1 - 6.8e-10 39.5 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO28111.1 - 8.1e-07 29.7 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO28111.1 - 1e-06 29.4 0.0 2.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO28111.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGO28111.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EGO28111.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_m1G_MT PF01746.21 EGO28112.1 - 1.2e-24 87.1 0.1 5.5e-19 68.6 0.1 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase eIF3_subunit PF08597.10 EGO28112.1 - 0.0018 18.3 6.9 0.003 17.5 6.9 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF1682 PF07946.14 EGO28112.1 - 6 6.0 9.9 10 5.2 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Abhydrolase_2 PF02230.16 EGO28113.1 - 9.1e-57 192.3 0.0 2.6e-56 190.9 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGO28113.1 - 1.7e-05 25.6 5.8 3e-05 24.7 5.8 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGO28113.1 - 2.6e-05 24.0 0.0 5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EGO28113.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGO28113.1 - 0.012 15.3 0.2 22 4.6 0.0 3.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO28113.1 - 0.053 13.0 0.0 7.5 6.0 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family PGAP1 PF07819.13 EGO28113.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioredoxin_4 PF13462.6 EGO28116.1 - 3.9e-10 40.1 0.0 1.5e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin STE3 PF02076.15 EGO28117.1 - 6.8e-68 229.0 23.5 1.8e-41 142.3 14.2 3.0 1 1 1 2 2 2 2 Pheromone A receptor LrgB PF04172.16 EGO28117.1 - 0.0029 17.1 1.1 0.0059 16.2 1.1 1.5 1 0 0 1 1 1 1 LrgB-like family Cyt-b5 PF00173.28 EGO28118.1 - 5.3e-21 74.5 0.1 7.1e-21 74.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4407 PF14362.6 EGO28120.1 - 0.14 11.5 2.3 0.083 12.2 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlgN PF05130.12 EGO28120.1 - 0.32 11.5 0.0 0.32 11.5 0.0 3.3 3 0 0 3 3 3 0 FlgN protein SLX9 PF15341.6 EGO28120.1 - 0.59 10.5 8.2 0.65 10.4 5.9 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Uso1_p115_C PF04871.13 EGO28120.1 - 0.59 10.5 14.0 0.58 10.5 8.5 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Macoilin PF09726.9 EGO28120.1 - 1.3 7.5 4.4 2.5 6.5 4.4 1.5 1 0 0 1 1 1 0 Macoilin family Spc24 PF08286.11 EGO28120.1 - 8.8 6.6 12.2 1.5 9.1 3.6 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 GatB_N PF02934.15 EGO28122.1 - 2.2e-108 361.8 0.0 2.7e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGO28122.1 - 3.2e-29 101.7 0.0 4.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 GatB domain PAP_central PF04928.17 EGO28124.1 - 2.7e-111 370.5 0.0 3.4e-111 370.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGO28124.1 - 3.9e-58 195.9 0.0 6.2e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGO28124.1 - 2.2e-11 43.9 0.0 7e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EGO28124.1 - 0.024 14.4 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 EGO28124.1 - 0.2 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Beta_helix PF13229.6 EGO28125.1 - 6.4e-09 35.9 26.1 3.4e-06 27.0 17.3 3.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EGO28125.1 - 0.018 14.3 16.1 1.6 7.9 16.1 2.8 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) RRM_1 PF00076.22 EGO28126.1 - 4.2e-08 32.9 0.0 1.2e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAGLU PF05089.12 EGO28130.1 - 8.6e-134 445.7 5.9 1.3e-133 445.1 5.9 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EGO28130.1 - 1.3e-71 241.3 4.3 2.1e-71 240.6 4.3 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EGO28130.1 - 5.9e-08 32.4 0.0 0.0016 18.2 0.0 2.8 2 0 0 2 2 2 2 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Hist_deacetyl PF00850.19 EGO28131.1 - 3.2e-78 263.3 0.1 4.2e-78 262.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HA2 PF04408.23 EGO28133.1 - 1.2e-19 70.6 0.0 3.6e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO28133.1 - 4.1e-16 59.1 0.0 9.5e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO28133.1 - 8.4e-13 48.6 0.0 4.3e-12 46.4 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO28133.1 - 1e-08 35.1 0.2 2.6e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGO28133.1 - 0.002 18.5 0.1 0.0049 17.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain Ig_6 PF18452.1 EGO28133.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain AAA_14 PF13173.6 EGO28133.1 - 0.018 15.1 0.1 4 7.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGO28133.1 - 0.024 14.9 1.1 0.09 13.0 0.4 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO28133.1 - 0.16 11.9 0.1 0.41 10.5 0.1 1.7 1 1 0 1 1 1 0 NACHT domain Tyrosinase PF00264.20 EGO28134.1 - 3.4e-32 112.5 0.1 4.7e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EGO28134.1 - 1.8e-06 28.6 0.0 5.1e-06 27.1 0.0 1.8 1 1 1 2 2 2 1 Tyosinase C-terminal domain NDUFA12 PF05071.16 EGO28136.1 - 5.7e-22 78.4 0.4 8.9e-22 77.7 0.4 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hydrophobin PF01185.18 EGO28137.1 - 2.6e-23 82.4 9.0 3.1e-23 82.2 9.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Nup_retrotrp_bd PF10599.9 EGO28137.1 - 2.9 8.6 5.1 3.4 8.4 0.1 2.1 1 1 1 2 2 2 0 Retro-transposon transporting motif CMAS PF02353.20 EGO28138.1 - 3.3e-58 197.1 0.0 4.3e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO28138.1 - 1.2e-07 32.3 0.0 2.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO28138.1 - 1.2e-05 25.8 0.0 2.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO28138.1 - 2.4e-05 24.2 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO28138.1 - 0.045 14.5 0.0 0.092 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EGO28138.1 - 0.047 14.7 0.5 0.94 10.5 0.0 3.0 4 0 0 4 4 4 0 Methyltransferase domain GCD14 PF08704.10 EGO28138.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RasGAP_C PF03836.15 EGO28139.1 - 2.5e-46 157.2 2.9 2.5e-46 157.2 2.9 2.6 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 EGO28139.1 - 5.3e-36 124.3 0.6 9.9e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EGO28139.1 - 2e-18 64.4 65.8 0.026 14.3 0.1 13.3 13 0 0 13 13 13 10 IQ calmodulin-binding motif CH PF00307.31 EGO28139.1 - 1.1e-13 51.4 0.0 3e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 EGO28139.1 - 0.99 9.4 4.6 0.29 11.1 0.6 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1664 PF07889.12 EGO28139.1 - 3.1 7.8 7.3 78 3.3 0.9 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) AA_permease PF00324.21 EGO28140.1 - 1.1e-114 383.6 44.8 1.3e-114 383.5 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO28140.1 - 2.3e-35 122.3 46.5 3.8e-35 121.6 46.5 1.3 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.11 EGO28140.1 - 0.012 15.4 0.1 0.012 15.4 0.1 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) NMO PF03060.15 EGO28141.1 - 2e-37 129.4 0.2 1.3e-36 126.7 0.2 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO28141.1 - 5.3e-05 22.4 1.0 0.1 11.6 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO28141.1 - 0.0085 15.2 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase WD40 PF00400.32 EGO28142.1 - 1.4e-16 60.5 2.0 2.6e-08 34.4 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO28142.1 - 2e-08 34.4 0.3 1e-05 25.7 0.0 4.1 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 EGO28142.1 - 0.012 15.9 2.0 0.061 13.7 1.8 2.2 2 0 0 2 2 2 0 Ring finger domain HOOK PF05622.12 EGO28142.1 - 0.014 13.6 4.9 0.018 13.2 4.9 1.1 1 0 0 1 1 1 0 HOOK protein zf-C3HC4_2 PF13923.6 EGO28142.1 - 0.014 15.2 1.3 0.014 15.2 1.3 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Ge1_WD40 PF16529.5 EGO28142.1 - 0.024 13.6 0.0 0.059 12.3 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1272 PF06906.11 EGO28142.1 - 0.033 14.3 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 EGO28142.1 - 0.058 13.3 3.3 0.16 11.8 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fmp27_WPPW PF10359.9 EGO28142.1 - 0.073 11.9 3.4 0.1 11.5 3.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-RING_10 PF16685.5 EGO28142.1 - 0.083 13.0 0.4 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Beta_helix_2 PF18835.1 EGO28142.1 - 0.094 12.5 0.8 6.9 6.5 0.0 2.9 1 1 1 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-RING_5 PF14634.6 EGO28142.1 - 0.11 12.5 3.7 0.48 10.4 3.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 EGO28142.1 - 0.12 11.8 0.6 0.29 10.6 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain APG6_N PF17675.1 EGO28142.1 - 0.29 11.6 5.6 0.43 11.1 5.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 EGO28142.1 - 0.3 10.7 5.5 0.47 10.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spectrin PF00435.21 EGO28142.1 - 0.51 10.8 4.8 0.92 10.0 4.8 1.3 1 0 0 1 1 1 0 Spectrin repeat TackOD1 PF18551.1 EGO28142.1 - 3.1 7.4 5.5 0.24 11.0 0.1 1.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 WD40 PF00400.32 EGO28143.1 - 1.9e-11 44.3 5.4 1.6e-08 35.1 0.2 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO28143.1 - 6e-09 36.1 0.0 0.00095 19.4 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGO28143.1 - 0.031 13.2 0.1 0.071 12.0 0.0 1.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 EGO28143.1 - 0.085 12.2 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal RVP_2 PF08284.11 EGO28148.1 - 0.0014 18.4 0.1 0.0023 17.7 0.1 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO28148.1 - 0.0051 17.3 0.0 0.012 16.2 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28148.1 - 0.0091 16.6 0.0 0.013 16.1 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 EGO28149.1 - 8e-07 28.9 5.8 8e-07 28.9 5.8 2.5 4 0 0 4 4 4 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28149.1 - 6e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 EGO28149.1 - 0.059 13.5 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4211 PF13926.6 EGO28149.1 - 0.29 11.2 1.6 0.72 9.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4211) zf-CCHC_3 PF13917.6 EGO28149.1 - 2.1 8.4 16.0 0.11 12.5 4.7 2.9 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGO28149.1 - 6 6.8 8.5 4.7 7.1 2.0 2.7 2 0 0 2 2 2 0 Zinc knuckle Plavaka PF18759.1 EGO28150.1 - 1.6e-47 162.3 0.1 1.9e-47 162.1 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 EGO28151.1 - 7.5e-30 104.3 0.2 2.1e-29 102.8 0.1 1.7 2 0 0 2 2 2 1 Plavaka transposase Pkinase_fungal PF17667.1 EGO28151.1 - 1.2e-05 24.3 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PA26 PF04636.13 EGO28152.1 - 0.0018 17.3 0.9 0.0032 16.4 0.2 1.6 1 1 1 2 2 2 1 PA26 p53-induced protein (sestrin) Ras PF00071.22 EGO28153.1 - 1.5e-54 183.9 0.0 2e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO28153.1 - 5.9e-34 116.9 0.0 8.7e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO28153.1 - 9e-15 54.6 0.0 3.6e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO28153.1 - 0.00013 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO28153.1 - 0.00033 20.1 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGO28153.1 - 0.00043 19.9 0.0 0.00056 19.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGO28153.1 - 0.00079 19.8 0.0 0.0014 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Retrotran_gag_2 PF14223.6 EGO28154.1 - 1.3e-06 28.1 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO28154.1 - 4.2e-05 23.1 0.1 7.6e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO28154.1 - 0.00019 21.2 0.0 0.00046 19.9 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 EGO28155.1 - 0.069 12.9 1.6 0.14 11.9 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-RING_10 PF16685.5 EGO28155.1 - 0.13 12.4 8.3 1.5 9.0 6.4 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 gag_pre-integrs PF13976.6 EGO28156.1 - 7.3e-11 41.8 0.6 1.2e-10 41.0 0.6 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain Mub_B2 PF17966.1 EGO28156.1 - 0.15 12.8 0.0 0.56 11.0 0.0 1.9 2 1 0 2 2 2 0 Mub B2-like domain Retrotrans_gag PF03732.17 EGO28157.1 - 0.0054 17.0 2.0 0.0054 17.0 2.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein GARS_A PF01071.19 EGO28158.1 - 5.2e-78 261.3 0.0 8.6e-78 260.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGO28158.1 - 7.5e-35 120.4 0.0 2.1e-34 118.9 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EGO28158.1 - 1.7e-33 115.3 0.7 1.7e-32 112.1 0.0 2.8 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EGO28158.1 - 8.2e-28 96.5 0.8 2.2e-27 95.2 0.8 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGO28158.1 - 2.5e-16 60.1 0.9 6.6e-15 55.6 1.2 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EGO28158.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF5496 PF17600.2 EGO28158.1 - 0.071 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5496) ATP-grasp_3 PF02655.14 EGO28158.1 - 0.096 12.7 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Cauli_VI PF01693.16 EGO28159.1 - 0.0075 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin ER-remodelling PF14755.6 EGO28159.1 - 0.24 11.7 6.7 0.41 10.9 6.7 1.6 1 1 0 1 1 1 0 Intracellular membrane remodeller Alpha_kinase PF02816.18 EGO28161.1 - 1.8e-06 28.2 0.0 2.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family DEK_C PF08766.11 EGO28163.1 - 0.45 10.5 2.0 57 3.7 0.0 3.9 4 0 0 4 4 4 0 DEK C terminal domain T_cell_tran_alt PF15128.6 EGO28166.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.7 1 1 1 2 2 2 0 T-cell leukemia translocation-altered DUF4574 PF15141.6 EGO28168.1 - 0.01 15.7 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 FYTT PF07078.11 EGO28170.1 - 0.029 13.7 1.8 0.039 13.3 1.8 1.1 1 0 0 1 1 1 0 Forty-two-three protein Radial_spoke_3 PF06098.11 EGO28170.1 - 0.13 11.5 4.6 0.17 11.1 4.6 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Cgr1 PF03879.14 EGO28170.1 - 0.65 10.4 14.3 1 9.8 14.3 1.2 1 0 0 1 1 1 0 Cgr1 family DUF4703 PF15775.5 EGO28170.1 - 1.7 8.4 8.5 14 5.5 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4703) DDE_3 PF13358.6 EGO28173.1 - 0.00061 19.6 0.0 0.008 15.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 EGO28174.1 - 1.1e-08 34.8 0.1 1.6e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO28174.1 - 0.0068 16.0 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF5314 PF17241.2 EGO28174.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5314) DUF1664 PF07889.12 EGO28177.1 - 0.056 13.5 0.2 0.13 12.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Gal11_ABD1 PF18535.1 EGO28178.1 - 0.2 11.8 0.6 0.6 10.2 0.6 1.8 1 1 0 1 1 1 0 Gal11 activator-binding domain (ABD1) Acyl_transf_3 PF01757.22 EGO28179.1 - 0.0043 16.2 1.7 0.0052 15.9 1.7 1.2 1 0 0 1 1 1 1 Acyltransferase family RVP_2 PF08284.11 EGO28180.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 EGO28182.1 - 2.5e-05 24.1 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO28182.1 - 0.0014 19.1 0.0 0.0019 18.7 0.0 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28182.1 - 0.0099 16.5 0.0 0.014 16.0 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease DUF2034 PF10356.9 EGO28183.1 - 0.087 12.2 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DEAD PF00270.29 EGO28185.1 - 1.6e-11 44.3 0.0 4.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO28185.1 - 1.4e-05 25.4 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO28185.1 - 0.00036 20.6 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Baculo_ME53 PF06061.11 EGO28185.1 - 0.052 12.8 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 Mito_carr PF00153.27 EGO28186.1 - 2.7e-63 209.9 6.5 1.3e-23 82.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cauli_VI PF01693.16 EGO28187.1 - 0.028 14.7 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin S100PBPR PF15427.6 EGO28189.1 - 1.3 8.2 9.3 0.31 10.2 5.6 1.6 1 1 1 2 2 2 0 S100P-binding protein Macoilin PF09726.9 EGO28189.1 - 4.7 5.7 5.9 5 5.5 5.9 1.0 1 0 0 1 1 1 0 Macoilin family RasGEF PF00617.19 EGO28190.1 - 9.9e-33 113.8 0.0 1.8e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO28190.1 - 5.4e-11 42.7 0.0 2.3e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 EGO28190.1 - 0.002 17.7 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 1 Ras family Viral_helicase1 PF01443.18 EGO28190.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EGO28190.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Filamin PF00630.19 EGO28193.1 - 0.039 14.8 0.1 4.3 8.2 0.1 2.2 1 1 1 2 2 2 0 Filamin/ABP280 repeat FAM163 PF15069.6 EGO28194.1 - 0.12 12.8 0.8 0.16 12.4 0.8 1.2 1 0 0 1 1 1 0 FAM163 family GTP_EFTU PF00009.27 EGO28195.1 - 2.5e-53 180.5 0.0 4.7e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO28195.1 - 1.7e-42 144.2 0.0 3.9e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGO28195.1 - 1.4e-14 54.3 1.7 1.4e-14 54.3 1.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO28195.1 - 0.0029 17.7 0.2 0.067 13.3 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 EGO28195.1 - 0.07 13.2 0.2 0.83 9.7 0.0 2.2 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain NIF3 PF01784.18 EGO28195.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Myb_DNA-bind_4 PF13837.6 EGO28196.1 - 3e-06 27.5 0.1 4.1e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGO28196.1 - 0.0047 17.9 0.1 0.0086 17.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF865 PF05906.11 EGO28196.1 - 0.16 11.8 0.2 0.44 10.4 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Zn_clus PF00172.18 EGO28198.1 - 2.4e-05 24.3 6.7 4.3e-05 23.5 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO28198.1 - 0.00015 20.9 0.2 0.00032 19.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AlkA_N PF06029.11 EGO28198.1 - 0.024 14.9 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 AlkA N-terminal domain Plavaka PF18759.1 EGO28199.1 - 2.1e-13 50.2 0.3 4.2e-13 49.2 0.1 1.5 2 0 0 2 2 2 1 Plavaka transposase Pkinase_fungal PF17667.1 EGO28199.1 - 0.00029 19.7 0.0 0.00041 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1456 PF07308.13 EGO28199.1 - 0.047 14.0 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) KH_1 PF00013.29 EGO28200.1 - 6.4e-39 131.6 2.8 1.1e-09 37.9 0.0 7.7 8 0 0 8 8 8 6 KH domain Plavaka PF18759.1 EGO28201.1 - 2.4e-16 59.9 0.1 4e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase NinD PF17466.2 EGO28203.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function Retrotran_gag_2 PF14223.6 EGO28205.1 - 3.8e-29 101.1 3.4 4.3e-29 100.9 3.4 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TPR_15 PF13429.6 EGO28205.1 - 0.048 12.9 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1018 PF06252.12 EGO28205.1 - 0.099 13.6 1.1 0.61 11.1 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) gag_pre-integrs PF13976.6 EGO28207.1 - 3.9e-11 42.7 0.1 6.3e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_4 PF14392.6 EGO28208.1 - 0.079 12.7 1.6 0.13 12.0 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle NRD1_2 PF01995.16 EGO28209.1 - 0.1 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 eIF3_subunit PF08597.10 EGO28212.1 - 5 7.0 14.1 7.3 6.4 14.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1414 PF07208.11 EGO28213.1 - 0.028 14.4 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) KDZ PF18758.1 EGO28215.1 - 7.9e-09 35.5 0.1 3e-06 27.0 0.0 2.4 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase BTB PF00651.31 EGO28219.1 - 2.8e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_8 PF01501.20 EGO28220.1 - 2.8e-14 53.3 0.0 4.4e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGO28220.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Mannosyltransferase putative Glyco_transf_24 PF18404.1 EGO28220.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 RRF_GI PF12614.8 EGO28221.1 - 0.011 15.8 0.6 0.025 14.7 0.6 1.5 1 0 0 1 1 1 0 Ribosome recycling factor Snapin_Pallidin PF14712.6 EGO28221.1 - 0.22 12.0 5.5 0.23 11.9 3.2 2.3 2 1 0 2 2 2 0 Snapin/Pallidin SKA2 PF16740.5 EGO28221.1 - 3.7 7.4 8.2 11 5.8 0.3 2.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 zf-CCHC PF00098.23 EGO28224.1 - 2.8e-06 27.1 0.4 5.2e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CHC2 PF01807.20 EGO28224.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 CHC2 zinc finger RVP_2 PF08284.11 EGO28225.1 - 5.1e-05 23.1 0.0 5.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO28225.1 - 0.00011 22.7 0.0 0.00039 20.9 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28225.1 - 0.0017 19.0 0.0 0.0033 18.0 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease ABC_tran_CTD PF16326.5 EGO28227.1 - 0.61 10.4 10.3 0.28 11.5 4.8 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF3886 PF13025.6 EGO28227.1 - 3 8.1 10.9 0.25 11.5 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) gag_pre-integrs PF13976.6 EGO28228.1 - 0.035 14.0 1.3 7.2 6.6 0.0 2.6 2 1 1 3 3 3 0 GAG-pre-integrase domain DUF2167 PF09935.9 EGO28229.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) DUF1192 PF06698.11 EGO28231.1 - 0.00067 19.6 0.7 0.0012 18.8 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Unstab_antitox PF09720.10 EGO28231.1 - 0.028 14.4 0.2 0.053 13.6 0.2 1.4 1 0 0 1 1 1 0 Putative addiction module component ORC6 PF05460.13 EGO28231.1 - 3.9 6.6 8.4 5.1 6.3 8.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PIF1 PF05970.14 EGO28232.1 - 6.8e-07 28.8 0.1 8.3e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 EGO28232.1 - 0.00045 20.6 0.0 0.00069 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO28232.1 - 0.0047 16.7 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGO28232.1 - 0.0098 15.7 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF3496 PF12001.8 EGO28236.1 - 0.011 16.0 1.7 0.011 16.0 1.7 7.2 4 2 5 9 9 9 0 Domain of unknown function (DUF3496) Nup54_57_C PF18570.1 EGO28236.1 - 4.5 7.0 9.8 7.4 6.3 0.3 3.7 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain DUF5617 PF18493.1 EGO28237.1 - 0.055 13.6 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) DUF1091 PF06477.13 EGO28240.1 - 0.031 14.7 0.4 5.7 7.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1091) HTH_OrfB_IS605 PF12323.8 EGO28240.1 - 0.042 13.3 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Cnd1_N PF12922.7 EGO28240.1 - 0.18 11.7 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 EGO28245.1 - 0.012 15.8 1.3 13 6.4 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat RTP1_C1 PF10363.9 EGO28245.1 - 0.055 13.6 0.0 4.4 7.5 0.0 3.0 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGO28245.1 - 0.11 13.0 4.3 6.2 7.4 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 EGO28245.1 - 0.55 10.4 7.1 0.66 10.1 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Phage_30_8 PF06019.11 EGO28246.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage GP30.8 protein MAGE_N PF12440.8 EGO28246.1 - 1.3 9.7 7.3 3.6 8.3 7.3 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Pkinase_fungal PF17667.1 EGO28247.1 - 2.2e-11 43.2 0.1 4.4e-11 42.2 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase zf-CCHC PF00098.23 EGO28251.1 - 0.0025 17.8 1.3 0.0042 17.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28251.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4939 PF16297.5 EGO28251.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 EGO28254.1 - 1.2e-06 28.7 0.0 1.2e-06 28.7 0.0 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein MCM_bind PF09739.9 EGO28257.1 - 0.16 10.4 0.7 0.18 10.2 0.7 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hepar_II_III PF07940.13 EGO28258.1 - 0.001 18.8 2.9 0.0053 16.4 3.0 1.9 1 1 0 1 1 1 1 Heparinase II/III-like protein Poty_coat PF00767.18 EGO28259.1 - 0.099 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Potyvirus coat protein DUF5113 PF17140.4 EGO28259.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Pkinase_fungal PF17667.1 EGO28262.1 - 0.00074 18.4 0.0 0.0017 17.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase TMEM126 PF07114.11 EGO28265.1 - 0.23 10.8 0.5 0.36 10.2 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 DUF4939 PF16297.5 EGO28270.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Anoct_dimer PF16178.5 EGO28270.1 - 0.036 13.8 0.5 0.097 12.4 0.1 1.8 2 0 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Sec8_exocyst PF04048.14 EGO28272.1 - 6.3e-31 107.2 0.8 2.2e-30 105.4 0.1 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EGO28272.1 - 1.7e-06 27.5 0.2 8.1e-06 25.3 0.3 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex IZUMO PF15005.6 EGO28272.1 - 0.7 10.4 2.1 27 5.3 1.2 3.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4800 PF16057.5 EGO28274.1 - 0.00082 18.7 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) zf-CCHC_4 PF14392.6 EGO28275.1 - 0.055 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO28275.1 - 0.18 11.6 0.3 0.18 11.6 0.3 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger DDE_1 PF03184.19 EGO28277.1 - 2.7e-09 36.9 0.1 4.7e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1926 PF09095.11 EGO28278.1 - 0.0078 15.9 0.3 0.0097 15.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1926) Pkinase PF00069.25 EGO28279.1 - 1.3e-46 159.1 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28279.1 - 1.9e-16 60.1 0.0 2.5e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO28279.1 - 0.006 15.9 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO28279.1 - 0.05 12.6 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HTH_Tnp_Tc5 PF03221.16 EGO28280.1 - 9.7e-07 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Mito_fiss_reg PF05308.11 EGO28282.1 - 0.38 10.8 12.2 3.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF1938 PF09153.10 EGO28283.1 - 0.05 13.7 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Retrotrans_gag PF03732.17 EGO28284.1 - 1.1e-06 28.9 0.5 2e-06 28.0 0.1 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO28284.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) FlxA PF14282.6 EGO28284.1 - 0.15 12.1 0.7 0.25 11.4 0.7 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF515 PF04415.12 EGO28287.1 - 0.065 11.6 3.5 4.7 5.5 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF515) FAD_binding_3 PF01494.19 EGO28287.1 - 0.29 10.3 0.0 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain PNISR PF15996.5 EGO28287.1 - 1.4 9.2 12.6 0.047 14.0 5.9 1.8 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR MRP-S27 PF10037.9 EGO28287.1 - 3.5 6.4 18.3 0.19 10.6 7.5 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 HATPase_c PF02518.26 EGO28288.1 - 7.4e-06 26.4 0.1 3.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Urotensin_II PF02083.15 EGO28288.1 - 0.096 12.4 0.3 0.21 11.4 0.3 1.5 1 0 0 1 1 1 0 Urotensin II RVT_2 PF07727.14 EGO28291.1 - 1.4e-06 28.2 0.1 0.0088 15.7 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EGO28291.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.6 EGO28292.1 - 4.1e-13 50.0 2.2 5.6e-12 46.3 0.0 2.7 2 1 1 3 3 3 2 Helitron helicase-like domain at N-terminus DUF2120 PF09893.9 EGO28294.1 - 0.62 10.2 4.5 0.42 10.7 2.5 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DivIC PF04977.15 EGO28294.1 - 3.3 7.5 8.9 0.14 11.9 2.7 1.9 2 0 0 2 2 2 0 Septum formation initiator PA28_beta PF02252.18 EGO28296.1 - 3e-53 179.4 1.8 3.9e-53 179.0 1.8 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EGO28296.1 - 1.8e-07 31.1 0.2 7.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit YqgC PF17430.2 EGO28298.1 - 0.1 12.7 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized YqgC-like Retrotrans_gag PF03732.17 EGO28299.1 - 4.7e-06 26.8 3.4 4.7e-06 26.8 3.4 3.0 2 2 1 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO28299.1 - 0.023 14.5 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DNA_ligase_A_M PF01068.21 EGO28300.1 - 8.3e-65 218.3 0.0 1.4e-64 217.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGO28300.1 - 6.6e-45 153.5 0.6 2.9e-44 151.4 0.3 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGO28300.1 - 1.2e-24 86.7 0.0 2.4e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 EGO28300.1 - 0.019 15.0 0.1 0.49 10.5 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain NIF PF03031.18 EGO28302.1 - 1.6e-23 83.2 0.0 1.3e-20 73.7 0.0 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EGO28302.1 - 2.7e-08 33.6 0.4 2.5e-07 30.5 0.3 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EGO28302.1 - 0.00028 21.2 0.1 0.00061 20.1 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ycf1 PF05758.12 EGO28304.1 - 0.34 8.7 0.4 0.36 8.6 0.4 1.0 1 0 0 1 1 1 0 Ycf1 Retrotrans_gag PF03732.17 EGO28305.1 - 2.7e-05 24.3 0.1 0.0001 22.5 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein E3_UbLigase_RBR PF18091.1 EGO28306.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain PP-binding PF00550.25 EGO28307.1 - 1.9e-13 50.6 0.3 2.4e-13 50.2 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGO28307.1 - 4.2e-05 23.7 0.2 5.1e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier SPRY PF00622.28 EGO28308.1 - 1e-20 74.0 0.0 1.8e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Med28 PF11594.8 EGO28308.1 - 0.2 11.7 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 Lectin_N PF03954.14 EGO28308.1 - 0.21 11.3 0.7 0.37 10.5 0.7 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DDE_1 PF03184.19 EGO28310.1 - 2.2e-31 108.9 0.1 3.3e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGO28310.1 - 5.3e-07 29.6 0.0 1.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain KDZ PF18758.1 EGO28311.1 - 4.4e-58 196.5 0.0 1.1e-57 195.2 0.0 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Tet_JBP PF12851.7 EGO28315.1 - 0.019 14.3 0.3 0.088 12.1 0.0 2.0 1 1 1 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily zf-CCHC PF00098.23 EGO28316.1 - 1.1e-05 25.3 2.0 2.6e-05 24.1 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28316.1 - 0.0014 18.8 2.6 0.0016 18.7 0.1 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO28316.1 - 0.059 13.3 3.6 0.13 12.2 3.6 1.6 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 EGO28317.1 - 2.5e-05 24.8 0.0 3.6e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28317.1 - 0.00019 22.0 0.0 0.00028 21.4 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO28317.1 - 0.0066 16.2 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Tweety PF04906.13 EGO28319.1 - 0.22 10.2 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Tweety TcdA_TcdB_pore PF12920.7 EGO28322.1 - 0.04 12.2 0.1 0.049 11.9 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Ecm29 PF13001.7 EGO28322.1 - 0.11 11.1 0.1 0.14 10.8 0.1 1.0 1 0 0 1 1 1 0 Proteasome stabiliser DUF89 PF01937.19 EGO28325.1 - 1.1e-109 366.7 0.1 1.3e-109 366.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 ADH_zinc_N PF00107.26 EGO28325.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HEPN_Apea PF18739.1 EGO28325.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Apea-like HEPN Orthopox_A47 PF06334.11 EGO28326.1 - 0.12 11.7 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A47 protein Bac_DnaA_C PF08299.11 EGO28327.1 - 0.043 13.8 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix Myb_DNA-bind_3 PF12776.7 EGO28328.1 - 4.3e-05 24.4 0.1 0.00011 23.1 0.1 1.6 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO28328.1 - 0.0099 16.2 0.2 0.05 14.0 0.2 2.1 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.6 EGO28329.1 - 0.14 12.7 0.0 0.18 12.4 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Shugoshin_N PF07558.11 EGO28332.1 - 0.1 12.5 0.7 0.2 11.5 0.7 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region ADIP PF11559.8 EGO28332.1 - 0.15 12.2 5.5 0.21 11.6 0.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HrpA_pilin PF09589.10 EGO28332.1 - 0.48 11.2 4.6 0.21 12.3 1.4 2.0 2 1 1 3 3 3 0 HrpA pilus formation protein HTH_37 PF13744.6 EGO28332.1 - 0.56 10.2 5.7 0.1 12.5 1.4 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4207 PF13904.6 EGO28332.1 - 0.76 9.4 6.7 0.076 12.7 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) DIL PF01843.19 EGO28334.1 - 9.4e-26 90.1 0.7 3.1e-25 88.5 0.7 2.0 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 EGO28334.1 - 8.8e-08 32.6 0.3 7e-06 26.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO28334.1 - 1.7e-06 28.5 0.0 5.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO28334.1 - 3.9e-06 27.0 0.1 3.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO28334.1 - 7.7e-06 26.1 0.2 0.12 12.8 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGO28334.1 - 0.00011 22.3 0.1 0.022 15.3 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat DUF4939 PF16297.5 EGO28341.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 EGO28341.1 - 8.5e-05 22.8 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 EGO28342.1 - 1e-08 34.9 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3591 PF12157.8 EGO28344.1 - 1.8e-70 237.8 1.2 1.8e-70 237.8 1.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EGO28344.1 - 6e-05 22.8 3.0 0.00012 21.8 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 EGO28344.1 - 0.0011 19.0 0.1 0.0022 18.1 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain SMN PF06003.12 EGO28344.1 - 0.0018 17.6 4.8 0.0018 17.6 0.5 2.2 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) zf-CCHC PF00098.23 EGO28344.1 - 0.33 11.1 3.3 0.59 10.3 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Plavaka PF18759.1 EGO28346.1 - 2.6e-23 82.8 0.1 6.6e-23 81.4 0.0 1.6 2 0 0 2 2 2 1 Plavaka transposase SMI1_KNR4 PF09346.10 EGO28346.1 - 0.16 12.4 0.8 0.54 10.6 0.1 2.2 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Plavaka PF18759.1 EGO28351.1 - 4.3e-15 55.7 0.3 5.5e-15 55.4 0.3 1.1 1 0 0 1 1 1 1 Plavaka transposase FlbT PF07378.11 EGO28352.1 - 0.089 12.9 0.2 0.24 11.5 0.2 1.6 1 1 0 1 1 1 0 Flagellar protein FlbT Helicase_C PF00271.31 EGO28354.1 - 4e-17 62.6 0.1 7.1e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGO28354.1 - 0.0036 16.6 0.1 0.0068 15.7 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EGO28355.1 - 1.7e-05 24.6 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 EGO28355.1 - 8.8e-05 21.5 0.0 9.1e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer EF-hand_6 PF13405.6 EGO28356.1 - 1.7e-11 43.1 2.0 5.8e-05 22.7 0.4 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGO28356.1 - 2.8e-10 40.5 1.2 9e-05 22.9 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGO28356.1 - 1.4e-06 27.4 4.9 0.0037 16.7 0.3 3.9 4 0 0 4 4 4 2 EF hand DUF1456 PF07308.13 EGO28356.1 - 0.0037 17.6 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) EF-hand_9 PF14658.6 EGO28356.1 - 0.037 14.3 0.0 3.4 8.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 EGO28356.1 - 2.2 7.9 6.4 0.18 11.4 0.8 2.1 3 0 0 3 3 3 0 EF hand CAF1C_H4-bd PF12265.8 EGO28357.1 - 3.2e-14 52.9 0.1 3e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGO28357.1 - 1.9e-13 50.6 11.7 1.6e-05 25.5 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO28357.1 - 1.3e-06 28.6 0.3 0.074 13.4 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain KDZ PF18758.1 EGO28359.1 - 1.4e-23 83.7 7.2 1.4e-23 83.7 7.2 3.0 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase zf-CCHC PF00098.23 EGO28360.1 - 3.6e-06 26.8 5.0 3.6e-06 26.8 5.0 2.3 3 0 0 3 3 3 1 Zinc knuckle gag-asp_proteas PF13975.6 EGO28361.1 - 8.4e-06 26.3 0.0 1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28361.1 - 0.0002 21.9 0.0 0.00022 21.8 0.0 1.2 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO28361.1 - 0.00039 20.2 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1771 PF08590.10 EGO28365.1 - 0.033 14.6 0.8 0.05 14.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_4 PF14392.6 EGO28365.1 - 0.053 13.3 1.6 0.088 12.6 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO28365.1 - 0.18 11.6 0.3 0.18 11.6 0.3 2.0 2 0 0 2 2 2 0 C2H2 zinc-finger DUF5424 PF17462.2 EGO28367.1 - 0.051 13.5 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5424) UPF0121 PF03661.13 EGO28368.1 - 6.7e-37 127.2 9.0 3.9e-35 121.4 9.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Myb_DNA-bind_3 PF12776.7 EGO28370.1 - 4.9e-08 33.9 0.1 9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO28370.1 - 0.015 15.7 0.3 0.036 14.4 0.3 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2800 PF10926.8 EGO28371.1 - 0.076 12.3 0.2 0.091 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) WD40 PF00400.32 EGO28379.1 - 1.6e-53 177.5 19.5 2.4e-06 28.2 0.0 12.1 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 EGO28379.1 - 1.7e-45 154.4 0.1 2.5e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGO28379.1 - 1.4e-09 38.2 5.1 0.53 10.6 0.0 8.1 6 1 3 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO28379.1 - 1e-08 34.9 0.1 1.4e-06 27.9 0.0 2.8 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 EGO28379.1 - 0.0031 16.2 3.1 3.3 6.3 0.0 4.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 EGO28379.1 - 0.0043 16.5 0.1 0.41 9.9 0.0 2.6 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region VID27 PF08553.10 EGO28379.1 - 0.0089 15.1 0.0 0.22 10.5 0.0 2.4 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 EGO28379.1 - 0.068 11.7 0.5 2.2 6.7 0.0 3.2 4 0 0 4 4 4 0 Cytochrome D1 heme domain bZIP_1 PF00170.21 EGO28381.1 - 4.4e-05 23.5 2.4 9.5e-05 22.4 2.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO28381.1 - 0.032 14.3 1.2 0.032 14.3 1.2 2.5 2 1 1 3 3 3 0 Basic region leucine zipper WD40 PF00400.32 EGO28383.1 - 2.6e-10 40.7 5.0 0.00014 22.6 1.1 3.2 2 1 1 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO28383.1 - 0.049 13.9 0.0 2 8.7 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HMG_box PF00505.19 EGO28384.1 - 1.2e-14 54.4 0.1 1.5e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO28384.1 - 0.0065 17.0 0.4 0.014 16.0 0.4 1.6 1 1 0 1 1 1 1 HMG-box domain Ribosomal_S14 PF00253.21 EGO28387.1 - 0.00046 19.9 0.1 0.00062 19.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1965 PF09248.10 EGO28388.1 - 0.092 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) 2-oxoacid_dh PF00198.23 EGO28393.1 - 2.9e-78 262.5 0.0 4.4e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGO28393.1 - 4.4e-19 68.1 2.3 8.7e-19 67.1 1.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EGO28393.1 - 2.9e-13 49.9 0.3 6.2e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 EGO28393.1 - 0.13 13.0 0.1 9.2 7.0 0.0 3.2 2 1 1 3 3 3 0 HlyD family secretion protein RVP PF00077.20 EGO28394.1 - 0.17 12.2 0.0 1.9 8.8 0.0 2.0 1 1 1 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EGO28395.1 - 5.7e-07 29.7 0.5 5.7e-07 29.7 0.5 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO28395.1 - 1.2e-06 28.4 6.7 2e-06 27.6 6.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-tcix PF14952.6 EGO28395.1 - 0.06 13.0 2.1 0.15 11.7 2.1 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zf-CCHC_5 PF14787.6 EGO28395.1 - 0.067 12.9 4.7 0.14 11.8 4.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger FlxA PF14282.6 EGO28395.1 - 0.086 12.8 0.5 0.18 11.8 0.5 1.5 1 0 0 1 1 1 0 FlxA-like protein zf-CCHC PF00098.23 EGO28396.1 - 3.1e-07 30.2 5.5 5e-07 29.5 5.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO28396.1 - 0.047 13.7 1.7 0.047 13.7 1.7 2.1 2 0 0 2 2 2 0 Zinc knuckle gag_pre-integrs PF13976.6 EGO28397.1 - 5.5e-11 42.2 0.3 1e-10 41.3 0.3 1.7 1 1 0 1 1 1 1 GAG-pre-integrase domain DUF1771 PF08590.10 EGO28398.1 - 0.044 14.2 1.4 0.086 13.2 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) zf-CCHC_4 PF14392.6 EGO28398.1 - 0.066 13.0 1.6 0.1 12.3 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO28398.1 - 0.1 12.3 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 EGO28398.1 - 0.2 11.5 1.9 1.1 9.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF3987 PF13148.6 EGO28399.1 - 0.054 12.5 3.2 0.09 11.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) THOC7 PF05615.13 EGO28399.1 - 0.67 10.2 6.6 0.089 13.1 2.2 1.8 2 0 0 2 2 2 0 Tho complex subunit 7 Pkinase_fungal PF17667.1 EGO28400.1 - 1.2e-15 57.2 0.0 1.5e-07 30.6 0.0 3.1 1 1 1 3 3 3 3 Fungal protein kinase Hist_deacetyl PF00850.19 EGO28401.1 - 8.5e-84 281.6 0.0 1.3e-83 281.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 EGO28401.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 NIL domain ORC6 PF05460.13 EGO28402.1 - 0.026 13.8 6.0 0.034 13.4 6.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3313 PF11769.8 EGO28403.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) CC2-LZ PF16516.5 EGO28404.1 - 0.013 15.8 0.2 0.05 14.0 0.0 1.8 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Lipoprotein_10 PF03202.13 EGO28404.1 - 0.066 13.6 1.2 2.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region DDE_3 PF13358.6 EGO28405.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sec2p PF06428.11 EGO28407.1 - 0.0091 16.0 1.1 0.013 15.5 1.1 1.2 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p RPN5_C PF18098.1 EGO28408.1 - 0.026 14.6 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain SGTA_dimer PF16546.5 EGO28409.1 - 9.9e-27 92.5 0.8 2.6e-26 91.2 0.8 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EGO28409.1 - 3.8e-12 45.5 0.5 2.7e-05 23.8 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO28409.1 - 2.7e-08 33.3 0.8 5.4e-08 32.4 0.8 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EGO28409.1 - 9.8e-08 31.6 0.7 0.0031 17.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO28409.1 - 4.9e-06 26.4 1.3 0.051 13.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO28409.1 - 2.4e-05 24.9 1.1 4e-05 24.2 1.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO28409.1 - 0.0023 17.8 1.4 0.016 15.1 0.3 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO28409.1 - 0.0034 17.3 0.2 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO28409.1 - 0.013 15.8 1.0 0.025 14.9 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO28409.1 - 0.025 14.8 1.9 0.36 11.1 1.9 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat MIF4G_like_2 PF09090.11 EGO28409.1 - 0.041 13.4 0.8 2 7.8 0.0 2.2 2 0 0 2 2 2 0 MIF4G like OPT PF03169.15 EGO28410.1 - 7.1e-185 616.2 52.0 8.6e-185 615.9 52.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PRELI PF04707.14 EGO28411.1 - 7.1e-37 126.7 0.0 8.2e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family TauD PF02668.16 EGO28412.1 - 2.5e-53 181.6 0.7 3.2e-53 181.2 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PorA PF11271.8 EGO28413.1 - 0.6 9.4 12.4 0.98 8.7 12.4 1.2 1 0 0 1 1 1 0 Porin PorA Pkinase PF00069.25 EGO28415.1 - 5.3e-67 226.0 0.0 8.5e-67 225.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28415.1 - 1.1e-37 129.7 0.0 6.7e-28 97.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO28415.1 - 2.1e-05 24.0 0.3 0.00021 20.7 0.3 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGO28415.1 - 0.0017 18.3 0.2 0.0098 15.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGO28415.1 - 0.0043 16.2 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGO28415.1 - 0.0066 15.3 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO28415.1 - 0.042 13.2 0.4 0.087 12.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1_Xtn PF16897.5 EGO28416.1 - 1.7e-43 147.0 1.6 3.2e-43 146.1 1.6 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGO28416.1 - 4.3e-21 74.7 0.0 6.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGO28416.1 - 2.1e-19 69.7 0.0 5.1e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO28416.1 - 3e-10 39.8 0.0 5.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO28416.1 - 0.0087 16.1 0.1 0.33 11.0 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MCM PF00493.23 EGO28416.1 - 0.06 12.4 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 EGO28416.1 - 0.077 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Lactamase_B_2 PF12706.7 EGO28417.1 - 4.3e-25 88.4 0.0 3.9e-17 62.4 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO28417.1 - 4.2e-07 30.2 1.2 1.1e-06 28.8 1.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGO28417.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PRELI PF04707.14 EGO28418.1 - 4.8e-31 107.7 0.0 5.6e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF1857 PF08982.11 EGO28418.1 - 0.043 13.7 0.0 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1857) CDtoxinA PF03498.14 EGO28418.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain RIC1 PF07064.13 EGO28420.1 - 5.6e-100 333.9 0.4 8.9e-100 333.3 0.4 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EGO28420.1 - 0.00016 21.9 0.0 0.0065 16.7 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO28420.1 - 0.0004 20.2 1.5 0.11 12.4 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Glyco_transf_28 PF03033.20 EGO28421.1 - 3.2e-31 108.2 0.0 1.1e-30 106.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EGO28421.1 - 9.3e-26 90.0 1.1 2.3e-15 56.5 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 EGO28421.1 - 8.2e-12 45.6 0.1 4.7e-11 43.1 0.2 2.2 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 EGO28421.1 - 6.8e-06 25.2 0.0 1.5e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.6 EGO28421.1 - 0.0022 18.3 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGO28421.1 - 0.016 15.7 1.1 0.99 9.9 1.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain SUR7 PF06687.12 EGO28422.1 - 1.1e-15 57.9 12.4 1.3e-15 57.6 12.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5480 PF17576.2 EGO28422.1 - 0.016 15.2 3.9 0.88 9.6 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5480) Claudin_2 PF13903.6 EGO28422.1 - 2.2 8.0 13.7 0.25 11.1 9.2 1.8 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Retrotrans_gag PF03732.17 EGO28423.1 - 2e-06 27.9 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein TIM21 PF08294.11 EGO28424.1 - 2.5e-23 82.6 0.0 2.3e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 TIM21 ATP-synt_F PF01990.17 EGO28425.1 - 3e-33 114.0 0.2 3.5e-33 113.8 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 EGO28425.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PIN_8 PF18476.1 EGO28425.1 - 0.03 14.2 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 PIN like domain SGT1 PF07093.11 EGO28426.1 - 1.3e-96 324.3 25.7 9.2e-94 315.0 17.7 3.9 2 1 0 2 2 2 2 SGT1 protein Helicase_C PF00271.31 EGO28427.1 - 0.0088 16.4 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO28427.1 - 0.073 12.8 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Clat_adaptor_s PF01217.20 EGO28428.1 - 2.3e-43 147.5 0.2 7.4e-43 145.9 0.2 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.14 EGO28429.1 - 1.1e-41 141.8 0.2 1.7e-41 141.2 0.2 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Rota_VP2 PF05087.12 EGO28429.1 - 0.15 10.1 0.2 0.21 9.7 0.2 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Nramp PF01566.18 EGO28430.1 - 2.6e-89 299.7 16.5 7.1e-50 170.0 2.5 2.3 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF3082 PF11282.8 EGO28430.1 - 1.4 9.2 15.5 0.032 14.5 3.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) Catalase PF00199.19 EGO28431.1 - 1.5e-172 574.0 0.3 2.2e-172 573.5 0.0 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 EGO28431.1 - 2.8e-18 65.9 0.0 5.6e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EGO28431.1 - 2.2e-13 50.1 0.0 4.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EGO28431.1 - 7.4e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3666 PF12408.8 EGO28431.1 - 0.04 13.1 0.1 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase zf-C2H2 PF00096.26 EGO28432.1 - 4.2e-07 30.1 18.4 1.2e-05 25.4 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO28432.1 - 2.4e-06 27.9 13.9 0.0032 18.2 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO28432.1 - 0.003 17.8 0.7 0.061 13.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 EGO28432.1 - 0.011 15.9 1.3 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 EGO28432.1 - 0.042 13.9 0.1 0.042 13.9 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO28432.1 - 0.056 13.9 2.3 0.056 13.9 2.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 EGO28432.1 - 1.2 9.0 8.5 7.6 6.4 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type C5HCH PF17982.1 EGO28432.1 - 7.4 6.8 11.5 0.47 10.6 2.2 2.8 2 1 0 3 3 3 0 NSD Cys-His rich domain Chalcone_2 PF16035.5 EGO28435.1 - 3.9e-28 98.7 0.0 8.6e-17 61.6 0.0 2.3 1 1 1 2 2 2 2 Chalcone isomerase like BLM10_mid PF16507.5 EGO28436.1 - 7.1e-189 628.8 0.0 1.4e-188 627.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGO28436.1 - 1.5e-31 108.1 0.4 1.1e-30 105.4 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EGO28436.1 - 1e-05 25.3 9.8 0.022 15.0 0.1 6.8 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 EGO28436.1 - 0.00037 20.8 0.2 0.029 14.8 0.0 4.1 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.23 EGO28436.1 - 0.0038 17.2 1.2 23 5.2 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat BLM10_N PF16547.5 EGO28436.1 - 0.076 13.3 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Cnd1 PF12717.7 EGO28436.1 - 0.087 12.9 0.1 0.47 10.5 0.1 2.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF3535 PF12054.8 EGO28436.1 - 0.096 11.9 0.5 0.99 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) DUF5355 PF17306.2 EGO28436.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5355) BCDHK_Adom3 PF10436.9 EGO28436.1 - 0.16 11.8 0.9 0.67 9.8 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase MTS PF05175.14 EGO28437.1 - 2e-06 27.5 0.0 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 EGO28437.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EGO28437.1 - 0.14 11.9 0.1 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase C2 PF00168.30 EGO28438.1 - 1.1e-84 279.4 0.1 6.4e-19 68.2 0.1 5.6 5 0 0 5 5 5 5 C2 domain MLVIN_C PF18697.1 EGO28438.1 - 0.13 12.3 0.1 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain p450 PF00067.22 EGO28439.1 - 1e-27 97.0 0.0 1.2e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 EGO28440.1 - 1.3e-22 79.6 0.4 2e-07 30.8 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein FAM176 PF14851.6 EGO28440.1 - 0.04 13.6 0.3 9.5 5.9 0.0 3.0 3 0 0 3 3 3 0 FAM176 family NmrA PF05368.13 EGO28441.1 - 9.2e-19 67.9 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO28441.1 - 7.4e-10 39.0 0.1 1.7e-09 37.8 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGO28441.1 - 4.8e-06 26.2 0.0 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 EGO28441.1 - 0.007 16.1 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein RmlD_sub_bind PF04321.17 EGO28441.1 - 0.11 11.6 0.1 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EGO28442.1 - 1.9e-16 60.3 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO28442.1 - 7.7e-12 45.5 0.5 6.6e-11 42.4 0.5 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO28442.1 - 1.7e-05 24.4 0.0 0.00018 21.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO28442.1 - 0.004 16.3 0.1 0.0071 15.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain IFR3_antag PF14754.6 EGO28442.1 - 0.046 12.9 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Papain-like auto-proteinase Bee_toxin PF17454.2 EGO28443.1 - 0.3 11.2 0.2 0.3 11.2 0.2 3.2 3 0 0 3 3 3 0 Honey bee toxin DUF3446 PF11928.8 EGO28443.1 - 1.2 9.5 7.2 1.6 9.1 0.3 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain Las1 PF04031.13 EGO28444.1 - 4e-47 160.2 1.6 7.7e-47 159.2 0.9 1.9 2 0 0 2 2 2 1 Las1-like Ysc84 PF04366.12 EGO28445.1 - 1.3e-37 128.4 0.6 2.2e-37 127.7 0.6 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGO28445.1 - 1.2e-16 60.0 0.1 2.7e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO28445.1 - 7.9e-14 51.3 0.0 5.5e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGO28445.1 - 7.5e-12 44.8 0.1 9.6e-11 41.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain PIF1 PF05970.14 EGO28447.1 - 0.039 13.1 0.0 0.061 12.5 0.0 1.4 1 1 1 2 2 2 0 PIF1-like helicase SH3_13 PF18335.1 EGO28449.1 - 0.018 14.9 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain DUF4926 PF16277.5 EGO28449.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) PIF1 PF05970.14 EGO28449.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase RhoGAP PF00620.27 EGO28450.1 - 3.2e-40 137.4 0.0 1.1e-39 135.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EGO28450.1 - 3.8e-07 30.3 0.6 3.8e-07 30.3 0.6 2.9 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain PhaC_N PF07167.13 EGO28450.1 - 0.2 11.3 1.0 0.99 9.0 0.1 2.4 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus HAD_2 PF13419.6 EGO28452.1 - 1.4e-22 80.6 0.0 1.7e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO28452.1 - 1.3e-13 51.7 0.0 4e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO28452.1 - 1.2e-11 44.5 0.1 3.1e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EGO28452.1 - 0.0019 18.6 0.2 0.005 17.3 0.2 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGO28452.1 - 0.079 13.1 0.0 0.63 10.2 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GHMP_kinases_N PF00288.26 EGO28453.1 - 5.6e-11 42.5 0.2 1.1e-10 41.6 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO28453.1 - 0.00096 19.5 0.0 0.0033 17.7 0.0 1.9 1 1 1 2 2 2 1 GHMP kinases C terminal AAA_6 PF12774.7 EGO28454.1 - 4.3e-125 417.0 0.0 6.3e-124 413.2 0.0 3.0 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGO28454.1 - 1.5e-110 370.1 5.7 1.5e-110 370.1 5.7 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGO28454.1 - 7e-73 244.4 7.0 7.3e-73 244.3 0.4 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGO28454.1 - 6.4e-67 225.6 0.0 3.7e-66 223.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGO28454.1 - 2.2e-51 174.9 0.0 7.1e-51 173.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGO28454.1 - 2.2e-42 144.6 0.0 1.9e-36 125.2 0.0 4.6 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 EGO28454.1 - 6.1e-39 134.0 5.9 1.1e-38 133.2 5.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EGO28454.1 - 5.1e-37 127.2 0.0 9.8e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGO28454.1 - 1.9e-29 102.2 0.0 2.1e-28 98.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGO28454.1 - 7.4e-27 94.0 0.0 3.6e-12 46.5 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGO28454.1 - 5.4e-18 65.3 0.2 3.1e-16 59.6 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGO28454.1 - 2.2e-12 47.4 0.0 0.0063 16.8 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 EGO28454.1 - 1.6e-11 44.8 0.1 0.019 15.4 0.0 4.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO28454.1 - 5.6e-11 42.8 3.3 0.1 12.8 0.0 6.0 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 EGO28454.1 - 9.3e-08 32.6 0.0 0.59 10.5 0.0 6.1 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 EGO28454.1 - 3.4e-07 30.8 1.2 0.15 12.6 0.0 5.8 6 0 0 6 6 4 2 AAA domain FtsK_SpoIIIE PF01580.18 EGO28454.1 - 2.8e-06 26.8 0.0 0.32 10.3 0.0 3.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family T2SSE PF00437.20 EGO28454.1 - 1.2e-05 24.5 0.0 0.013 14.6 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGO28454.1 - 1.3e-05 24.7 0.4 0.66 9.3 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGO28454.1 - 9e-05 22.8 2.7 0.31 11.4 0.0 5.1 5 0 0 5 5 5 1 AAA domain TrwB_AAD_bind PF10412.9 EGO28454.1 - 0.00018 20.6 0.0 0.5 9.2 0.0 3.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_lid_1 PF17857.1 EGO28454.1 - 0.00031 20.9 3.3 0.00034 20.8 0.0 2.8 3 0 0 3 3 1 1 AAA+ lid domain AAA_29 PF13555.6 EGO28454.1 - 0.00057 19.6 0.1 0.76 9.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO28454.1 - 0.0021 18.5 0.0 9.7 6.7 0.0 4.3 3 0 0 3 3 3 0 ABC transporter IstB_IS21 PF01695.17 EGO28454.1 - 0.0043 16.8 0.4 0.8 9.4 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein LOH1CR12 PF10158.9 EGO28454.1 - 0.0046 17.0 13.6 0.13 12.3 0.3 4.3 4 0 0 4 4 2 2 Tumour suppressor protein RNA_helicase PF00910.22 EGO28454.1 - 0.018 15.4 0.0 73 3.8 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 EGO28454.1 - 0.025 14.3 1.8 23 4.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain DUF3584 PF12128.8 EGO28454.1 - 0.031 11.8 29.5 0.11 10.0 0.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) AAA_25 PF13481.6 EGO28454.1 - 0.032 13.8 0.0 0.7 9.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGO28454.1 - 0.065 13.0 0.0 4.6 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EGO28454.1 - 0.067 13.1 1.3 39 4.1 0.1 4.6 4 0 0 4 4 3 0 NACHT domain ERM PF00769.19 EGO28454.1 - 0.07 12.9 23.9 0.28 10.9 4.2 2.9 3 0 0 3 3 2 0 Ezrin/radixin/moesin family Rad17 PF03215.15 EGO28454.1 - 0.071 13.0 0.1 26 4.7 0.0 4.3 5 0 0 5 5 4 0 Rad17 P-loop domain TsaE PF02367.17 EGO28454.1 - 0.074 13.1 0.9 21 5.2 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EGO28454.1 - 0.086 12.6 0.3 11 5.7 0.1 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EGO28454.1 - 0.14 11.8 1.9 43 3.6 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain ResIII PF04851.15 EGO28454.1 - 0.15 12.1 0.4 39 4.2 0.0 4.0 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit dNK PF01712.19 EGO28454.1 - 0.16 11.8 1.8 0.42 10.4 0.5 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase YabA PF06156.13 EGO28454.1 - 1.3 9.7 18.1 23 5.7 2.9 4.3 3 0 0 3 3 3 0 Initiation control protein YabA AAA_11 PF13086.6 EGO28454.1 - 7.4 6.3 14.3 1.3 8.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain UPF0242 PF06785.11 EGO28454.1 - 9 6.3 18.4 4.7 7.3 1.5 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phlebovirus_NSM PF07246.11 EGO28454.1 - 9.7 5.5 10.5 0.064 12.6 0.5 2.2 2 0 0 2 2 1 0 Phlebovirus nonstructural protein NS-M Romo1 PF10247.9 EGO28461.1 - 2.5e-26 91.8 10.7 3.7e-26 91.3 10.7 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 L51_S25_CI-B8 PF05047.16 EGO28462.1 - 4.7e-10 39.2 0.0 7.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MFS_1 PF07690.16 EGO28463.1 - 5.7e-43 147.2 34.5 1e-27 97.0 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGO28463.1 - 1.9e-06 27.0 22.3 0.019 13.8 6.6 3.3 2 2 1 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 EGO28463.1 - 4.3e-06 25.5 20.5 0.00027 19.6 1.0 3.5 3 1 0 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.24 EGO28463.1 - 0.00047 19.1 12.1 0.00047 19.1 12.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGO28463.1 - 0.03 13.6 20.3 0.29 10.4 7.4 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGO28463.1 - 0.084 11.2 10.3 0.035 12.4 1.6 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2715 PF10895.8 EGO28463.1 - 4.2 7.0 5.4 1.4 8.6 1.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2715) H2TH PF06831.14 EGO28464.1 - 1.7e-21 76.0 0.0 2.6e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EGO28464.1 - 4.3e-09 37.0 0.0 8.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 EGO28464.1 - 0.002 17.0 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Beta-lactamase PF00144.24 EGO28465.1 - 3.7e-39 134.9 0.0 5.1e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EGO28465.1 - 0.048 14.1 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) HATPase_c PF02518.26 EGO28466.1 - 1.6e-25 89.8 0.0 4.2e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO28466.1 - 1.1e-17 64.2 0.0 3.5e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGO28466.1 - 8.4e-15 54.6 1.3 1.2e-13 50.9 0.0 3.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EGO28466.1 - 9.6e-14 52.1 0.2 5.3e-12 46.4 0.1 3.1 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 EGO28466.1 - 2.4e-09 37.6 0.0 5.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EGO28466.1 - 8.3e-07 29.7 0.0 2.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EGO28466.1 - 0.00051 20.4 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain NACHT PF05729.12 EGO28466.1 - 0.00087 19.2 3.4 0.48 10.3 0.2 3.5 3 0 0 3 3 3 2 NACHT domain Pkinase PF00069.25 EGO28466.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF815 PF05673.13 EGO28466.1 - 0.023 13.9 0.0 0.056 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF929 PF06053.11 EGO28466.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) MeaB PF03308.16 EGO28466.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGO28466.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase TPR_16 PF13432.6 EGO28466.1 - 5.9 7.6 7.8 73 4.1 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 EGO28467.1 - 6.9e-37 126.9 0.1 1.2e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO28467.1 - 2.9e-27 95.2 0.0 7.8e-25 87.4 0.0 2.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGO28467.1 - 4.5e-09 36.5 0.0 7.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Retrotrans_gag PF03732.17 EGO28468.1 - 1.1e-08 35.2 0.3 1.1e-08 35.2 0.3 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO28468.1 - 1.4e-06 28.1 2.3 2.9e-06 27.1 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Mito_carr PF00153.27 EGO28470.1 - 4.4e-53 177.2 0.6 3.1e-18 65.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.14 EGO28471.1 - 1.3e-12 47.6 4.5 2.3e-12 46.8 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EGO28471.1 - 0.046 14.0 8.3 0.029 14.7 4.1 2.4 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) TMEM135_C_rich PF15982.5 EGO28472.1 - 1.6e-05 25.5 0.1 2.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 DEAD PF00270.29 EGO28473.1 - 1.2e-36 126.1 0.0 3.2e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO28473.1 - 5.4e-24 84.7 0.0 1.1e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO28473.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3802 PF12290.8 EGO28473.1 - 0.16 12.5 0.1 0.35 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) HMG_box PF00505.19 EGO28474.1 - 7.7e-15 55.1 1.8 9.5e-15 54.8 1.8 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO28474.1 - 3.1e-06 27.7 0.4 3.7e-06 27.4 0.4 1.1 1 0 0 1 1 1 1 HMG-box domain Peptidase_M61 PF05299.12 EGO28474.1 - 0.032 14.6 0.1 0.038 14.4 0.1 1.0 1 0 0 1 1 1 0 M61 glycyl aminopeptidase PolyA_pol PF01743.20 EGO28476.1 - 6e-27 94.6 0.1 1.2e-26 93.6 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGO28476.1 - 1.2e-06 28.2 0.1 2.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Arm PF00514.23 EGO28477.1 - 4.3e-70 229.8 30.2 7.9e-13 48.0 0.1 11.7 11 1 1 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGO28477.1 - 9e-19 67.6 12.1 0.00093 19.6 0.3 7.8 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EGO28477.1 - 5.5e-18 65.1 6.4 0.0017 18.7 0.0 7.0 4 3 2 6 6 6 5 HEAT repeats HEAT PF02985.22 EGO28477.1 - 2.9e-14 51.9 14.3 0.55 10.6 0.0 9.5 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.13 EGO28477.1 - 3.5e-11 43.1 10.1 1.3e-07 31.4 1.5 2.4 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 EGO28477.1 - 1e-10 40.8 11.3 1.6e-07 30.3 0.2 2.7 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 EGO28477.1 - 1.3e-09 36.8 1.6 1.9e-09 36.3 1.6 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EGO28477.1 - 3.8e-08 33.0 9.0 0.0047 16.2 0.4 4.5 2 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 EGO28477.1 - 1e-06 28.9 6.5 0.0071 16.4 0.2 4.9 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EGO28477.1 - 0.0012 18.8 8.7 1.4 8.8 0.0 4.1 2 1 1 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EGO28477.1 - 0.0035 17.4 3.3 38 4.4 0.1 5.0 2 1 4 7 7 7 0 V-ATPase subunit H HEAT_PBS PF03130.16 EGO28477.1 - 0.015 15.9 10.1 57 4.8 0.2 7.3 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGO28477.1 - 0.054 14.1 0.1 12 6.6 0.0 3.4 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EGO28477.1 - 0.085 13.0 3.4 26 5.0 0.0 4.0 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 EGO28477.1 - 0.34 11.0 4.7 0.49 10.4 0.2 3.4 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_16 PF00722.21 EGO28478.1 - 1.8e-05 24.3 0.0 4.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BAG PF02179.16 EGO28479.1 - 4.5e-06 27.0 0.0 9.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 BAG domain Acatn PF13000.7 EGO28480.1 - 9e-140 466.8 28.4 4.7e-69 233.3 17.7 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.22 EGO28481.1 - 7.5e-62 209.6 0.0 9.8e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KH_2 PF07650.17 EGO28481.1 - 0.11 12.3 0.3 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 KH domain NAP PF00956.18 EGO28482.1 - 7.6e-22 77.8 3.6 7.6e-22 77.8 3.6 3.4 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Astro_capsid_p PF12226.8 EGO28482.1 - 0.95 8.6 4.7 1.5 7.9 4.7 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Syja_N PF02383.18 EGO28483.1 - 1.1e-85 287.8 0.0 1.5e-85 287.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain TAP42 PF04177.12 EGO28483.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 TAP42-like family LRR_9 PF14580.6 EGO28484.1 - 1.7e-62 210.0 0.3 3.1e-62 209.2 0.1 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGO28484.1 - 6.9e-10 39.0 13.5 3.5e-06 27.2 4.6 3.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO28484.1 - 3.5e-07 29.9 2.8 1.3e-06 28.0 2.9 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 EGO28484.1 - 0.053 13.6 1.8 3.9 7.8 0.3 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Nop PF01798.18 EGO28484.1 - 1.1 8.7 4.0 23 4.3 0.0 2.9 2 1 1 3 3 3 0 snoRNA binding domain, fibrillarin LRR_1 PF00560.33 EGO28484.1 - 2 9.3 4.5 73 4.5 0.4 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat MitMem_reg PF13012.6 EGO28485.1 - 2.9e-24 85.6 0.0 5.4e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGO28485.1 - 1.8e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MCM PF00493.23 EGO28486.1 - 9.1e-103 342.2 0.0 4.1e-102 340.0 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGO28486.1 - 1.2e-33 115.6 0.0 2.8e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO28486.1 - 1.1e-30 105.9 0.7 2.4e-30 104.8 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO28486.1 - 6.3e-15 55.6 0.8 1.1e-14 54.9 0.1 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO28486.1 - 8.5e-07 28.6 0.0 0.00024 20.6 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO28486.1 - 8.4e-05 22.6 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGO28486.1 - 0.0002 21.2 0.1 0.0022 17.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGO28486.1 - 0.031 14.9 0.8 0.24 12.1 0.1 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 EGO28486.1 - 0.078 13.4 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-CCHC PF00098.23 EGO28487.1 - 3.4e-08 33.2 5.7 6.7e-08 32.3 5.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28487.1 - 5.2e-08 33.0 5.5 1.2e-07 31.8 4.2 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO28487.1 - 1.2 9.1 7.6 3.5 7.7 7.6 1.7 1 1 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.19 EGO28488.1 - 1e-16 61.1 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SL4P PF17618.2 EGO28488.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein DDE_3 PF13358.6 EGO28488.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease NmrA PF05368.13 EGO28489.1 - 4.9e-17 62.3 0.0 6.3e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO28489.1 - 8.5e-08 32.3 0.0 4.5e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGO28489.1 - 0.0039 16.7 0.0 0.0088 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGO28489.1 - 0.18 11.2 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase BPL_LplA_LipB PF03099.19 EGO28491.1 - 5.5e-08 32.8 0.0 8.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ATP11 PF06644.11 EGO28492.1 - 1.1e-72 245.1 0.0 4.6e-72 243.1 0.0 1.7 1 1 0 1 1 1 1 ATP11 protein Ammonium_transp PF00909.21 EGO28494.1 - 2.1e-115 385.7 24.1 2.4e-115 385.4 24.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Prenylcys_lyase PF07156.14 EGO28495.1 - 2.1e-71 240.9 0.0 2.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EGO28495.1 - 1.2e-12 47.9 0.1 1.7e-11 44.1 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO28495.1 - 2.7e-10 40.3 0.0 1.1e-09 38.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO28495.1 - 1.5e-07 31.3 3.5 2.1e-06 27.6 3.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO28495.1 - 0.00033 20.0 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO28495.1 - 0.011 15.7 0.0 0.81 9.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding F-box PF00646.33 EGO28496.1 - 0.00097 19.0 0.1 0.0053 16.6 0.0 2.3 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 EGO28496.1 - 0.0013 18.6 0.8 0.0027 17.6 0.8 1.6 1 0 0 1 1 1 1 F-box-like NUDIX PF00293.28 EGO28497.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain FlxA PF14282.6 EGO28501.1 - 0.0087 16.0 0.3 0.01 15.8 0.3 1.1 1 0 0 1 1 1 1 FlxA-like protein Myb_DNA-bind_3 PF12776.7 EGO28503.1 - 2.3e-07 31.7 0.1 2.8e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NUDIX PF00293.28 EGO28505.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.15 EGO28506.1 - 1.1e-103 346.8 0.0 1.5e-103 346.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGO28506.1 - 5.3e-63 211.5 0.0 9.2e-63 210.7 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EGO28506.1 - 9.2e-07 29.3 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.15 EGO28507.1 - 5.7e-09 35.9 11.2 4.2e-08 33.1 11.4 2.0 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EGO28507.1 - 1.6e-05 24.9 4.6 2.9e-05 24.1 4.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor CCDC85 PF10226.9 EGO28507.1 - 0.0043 16.8 1.3 0.0043 16.8 1.3 1.5 2 0 0 2 2 2 1 CCDC85 family bZIP_Maf PF03131.17 EGO28507.1 - 0.048 14.2 3.2 0.097 13.2 3.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CHCH PF06747.13 EGO28508.1 - 1.1e-07 31.8 1.6 2.3e-07 30.8 1.5 1.6 1 1 1 2 2 2 1 CHCH domain NDUF_B7 PF05676.13 EGO28508.1 - 0.0058 16.3 0.8 0.0076 15.9 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 EGO28508.1 - 0.0092 16.3 2.1 0.018 15.3 2.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGO28508.1 - 0.016 15.2 1.1 0.023 14.7 1.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 EGO28508.1 - 0.04 14.2 0.5 0.063 13.5 0.5 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 EGO28508.1 - 0.068 13.6 0.5 0.11 12.9 0.5 1.3 1 0 0 1 1 1 0 GCK domain CKS PF01111.19 EGO28508.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit GDPD PF03009.17 EGO28511.1 - 1.9e-32 113.0 0.0 2.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGO28511.1 - 0.00038 20.8 1.5 0.0016 18.9 1.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family UCR_TM PF02921.14 EGO28512.1 - 4.7e-12 46.2 0.4 1.5e-11 44.6 0.4 1.9 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EGO28512.1 - 8.8e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase PF00069.25 EGO28513.1 - 1.4e-49 168.9 0.0 2.3e-49 168.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28513.1 - 1e-34 120.0 0.0 7.3e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO28513.1 - 1.1e-05 24.4 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_sulf_C PF12411.8 EGO28513.1 - 0.0016 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Kinase-like PF14531.6 EGO28513.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EGO28514.1 - 6.7e-43 147.0 0.0 2.5e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28514.1 - 3.3e-11 43.0 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO28514.1 - 0.022 13.5 0.1 0.052 12.3 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 EGO28515.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGO28515.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain PSD2 PF07624.11 EGO28515.1 - 0.11 12.3 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) F-box_4 PF15966.5 EGO28515.1 - 0.11 12.4 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 F-box ERAP1_C PF11838.8 EGO28515.1 - 0.22 11.1 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain p450 PF00067.22 EGO28516.1 - 1.1e-57 195.9 0.0 2.4e-56 191.4 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_5 PF13873.6 EGO28516.1 - 0.27 11.3 0.9 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SprT-like PF10263.9 EGO28517.1 - 2.4e-08 33.8 0.1 3.6e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.10 EGO28517.1 - 0.06 13.5 2.6 0.1 12.7 2.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 EGO28517.1 - 0.064 13.2 4.5 0.13 12.2 4.5 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Copper-fist PF00649.18 EGO28519.1 - 1.4e-20 72.5 1.3 1.4e-20 72.5 1.3 3.1 3 0 0 3 3 3 1 Copper fist DNA binding domain Glyco_hydro_72 PF03198.14 EGO28520.1 - 1.1e-91 307.4 0.2 1.9e-91 306.6 0.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGO28520.1 - 9.1e-16 58.3 0.7 3.8e-15 56.3 0.7 2.2 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EGO28520.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ABC_membrane PF00664.23 EGO28521.1 - 4e-46 157.9 30.3 5.9e-23 81.9 9.0 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGO28521.1 - 3.4e-39 134.5 8.8 1.5e-25 90.3 0.1 3.4 4 1 0 4 4 2 2 ABC transporter SMC_N PF02463.19 EGO28521.1 - 3.6e-11 42.9 5.8 0.0011 18.5 0.4 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EGO28521.1 - 4.4e-05 23.2 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO28521.1 - 6e-05 23.5 0.3 0.51 10.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGO28521.1 - 6.8e-05 22.5 0.6 0.13 12.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EGO28521.1 - 0.00013 21.6 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 EGO28521.1 - 0.00014 22.2 0.1 0.2 11.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGO28521.1 - 0.00023 21.1 4.7 0.46 10.2 0.1 4.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGO28521.1 - 0.00025 20.2 0.0 0.12 11.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 EGO28521.1 - 0.00026 21.6 5.0 0.0024 18.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EGO28521.1 - 0.002 18.2 1.1 0.65 10.1 0.1 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO28521.1 - 0.0023 17.8 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGO28521.1 - 0.0049 16.2 0.1 0.73 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 EGO28521.1 - 0.0087 14.9 0.0 0.063 12.1 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF87 PF01935.17 EGO28521.1 - 0.011 15.8 5.7 0.11 12.5 0.3 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EGO28521.1 - 0.02 14.6 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.15 EGO28521.1 - 0.021 14.8 0.1 0.78 9.7 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGO28521.1 - 0.03 14.0 0.1 0.72 9.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO28521.1 - 0.033 14.7 0.6 7.7 7.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGO28521.1 - 0.036 13.0 0.8 4.5 6.1 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 EGO28521.1 - 0.04 13.4 0.6 9.1 5.7 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.29 EGO28521.1 - 0.044 13.6 0.2 13 5.5 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 EGO28521.1 - 0.14 12.2 0.6 14 5.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGO28521.1 - 0.14 11.9 1.3 1.2 8.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EGO28521.1 - 0.14 12.6 0.8 3 8.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Presenilin PF01080.17 EGO28521.1 - 0.23 10.2 9.5 2.1 7.0 3.5 2.6 2 0 0 2 2 2 0 Presenilin AAA_15 PF13175.6 EGO28521.1 - 0.5 10.0 0.0 0.5 10.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 EGO28521.1 - 0.84 9.7 6.8 2.6 8.1 0.1 2.9 3 0 0 3 3 2 0 Dynamin family NUP214 PF16755.5 EGO28521.1 - 1 8.5 5.6 0.8 8.9 0.5 2.4 3 0 0 3 3 3 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40 PF00400.32 EGO28522.1 - 2.5e-26 91.4 8.5 2.9e-06 27.9 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EGO28522.1 - 1.1e-06 27.6 0.1 0.0051 15.5 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGO28522.1 - 0.0049 17.1 0.0 8.5 6.8 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BC10 PF06726.12 EGO28523.1 - 1.1e-09 38.4 11.3 1.9e-09 37.6 11.3 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 CS PF04969.16 EGO28524.1 - 0.0075 17.3 0.0 0.015 16.3 0.0 1.6 1 0 0 1 1 1 1 CS domain Dsl1_N PF11988.8 EGO28524.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal Sporozoite_P67 PF05642.11 EGO28524.1 - 0.48 8.5 10.5 0.6 8.1 10.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Forkhead_N PF08430.12 EGO28524.1 - 1.3 9.6 22.2 2 9.0 22.2 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region p450 PF00067.22 EGO28525.1 - 1.3e-52 179.1 0.0 1.8e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF883 PF05957.13 EGO28526.1 - 9.5e-05 22.9 14.2 0.0025 18.4 5.5 2.1 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 EGO28526.1 - 0.00023 21.1 4.4 0.00029 20.8 4.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EGO28526.1 - 0.00057 20.4 14.4 0.009 16.5 1.5 2.2 1 1 1 2 2 2 2 YtxH-like protein EspB PF05802.11 EGO28526.1 - 0.0081 16.2 10.1 0.0097 15.9 10.1 1.1 1 0 0 1 1 1 1 Enterobacterial EspB protein tRNA-synt_1e PF01406.19 EGO28526.1 - 0.0088 15.4 0.6 0.0095 15.3 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain LEA_4 PF02987.16 EGO28526.1 - 0.024 14.7 9.3 0.024 14.7 9.3 3.5 1 1 3 4 4 4 0 Late embryogenesis abundant protein PV-1 PF06637.11 EGO28526.1 - 0.03 13.1 3.8 0.033 13.0 3.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) HisKA_3 PF07730.13 EGO28526.1 - 0.065 13.8 2.8 0.49 11.0 1.4 2.3 1 1 0 2 2 2 0 Histidine kinase Alanine_zipper PF11839.8 EGO28526.1 - 0.22 11.9 12.0 0.1 12.9 8.7 2.2 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein TMP_2 PF06791.13 EGO28526.1 - 0.37 10.4 9.0 3.3 7.3 0.6 2.0 1 1 1 2 2 2 0 Prophage tail length tape measure protein LEA_1 PF03760.15 EGO28526.1 - 0.7 10.6 21.2 0.32 11.7 10.1 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 DUF948 PF06103.11 EGO28526.1 - 4 7.8 6.2 2.4e+02 2.0 6.2 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RVP_2 PF08284.11 EGO28528.1 - 0.00026 20.8 0.0 0.00044 20.0 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO28528.1 - 0.0071 17.0 0.0 0.01 16.5 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO28528.1 - 0.0076 16.8 0.0 0.013 16.1 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-C2H2_10 PF16588.5 EGO28529.1 - 0.028 14.2 0.4 0.055 13.2 0.4 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 EGO28529.1 - 0.029 14.1 1.6 0.045 13.5 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF1771 PF08590.10 EGO28529.1 - 0.11 12.9 0.4 0.17 12.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) MT-A70 PF05063.14 EGO28530.1 - 8.4e-41 139.7 0.0 1.6e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 EGO28530.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Noc2 PF03715.13 EGO28531.1 - 3.2e-118 394.3 2.1 2.6e-117 391.3 0.6 2.2 2 0 0 2 2 2 2 Noc2p family CSN8_PSD8_EIF3K PF10075.9 EGO28532.1 - 0.05 13.6 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family HSP70 PF00012.20 EGO28535.1 - 8.1e-05 21.0 0.0 0.00015 20.1 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 EGO28535.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.13 EGO28535.1 - 0.19 10.5 0.1 0.74 8.6 0.2 1.8 2 0 0 2 2 2 0 MreB/Mbl protein ALO PF04030.14 EGO28536.1 - 7.6e-76 255.3 0.2 9.4e-76 255.1 0.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EGO28536.1 - 6.6e-26 90.7 0.2 1.1e-25 90.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.26 EGO28537.1 - 8.4e-45 151.9 0.0 9.5e-45 151.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO28537.1 - 0.19 11.4 0.0 0.63 9.7 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B RNA_pol_Rpb2_6 PF00562.28 EGO28538.1 - 5.7e-119 397.7 1.0 1.3e-108 363.6 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGO28538.1 - 9.9e-57 191.7 0.0 1.7e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGO28538.1 - 4.5e-32 110.3 0.2 1.1e-31 109.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGO28538.1 - 1.5e-27 96.5 0.0 4.1e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGO28538.1 - 2.2e-24 85.5 2.7 6.3e-24 84.0 1.9 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGO28538.1 - 2.1e-20 72.6 0.2 5.6e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGO28538.1 - 3e-11 43.7 0.9 9.9e-11 42.0 0.9 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SNF2_N PF00176.23 EGO28540.1 - 8.8e-37 126.6 0.1 1.3e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO28540.1 - 1.2e-20 73.9 0.0 2.8e-18 66.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO28540.1 - 0.00035 20.6 0.0 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO28540.1 - 0.00091 18.5 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase VIGSSK PF14773.6 EGO28540.1 - 0.001 19.1 0.4 0.0055 16.8 0.0 2.2 1 1 1 2 2 2 1 Helicase-associated putative binding domain, C-terminal SWI2_SNF2 PF18766.1 EGO28540.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UQ_con PF00179.26 EGO28541.1 - 3.9e-45 153.0 0.0 4.8e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO28541.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.4 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF2463 PF09591.10 EGO28542.1 - 0.025 14.4 4.1 1.5 8.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2463) DUF2157 PF09925.9 EGO28542.1 - 0.062 13.1 2.5 0.087 12.6 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 EGO28542.1 - 2.1 8.0 5.5 0.89 9.2 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-CCHC PF00098.23 EGO28543.1 - 9.3e-07 28.7 4.3 9.3e-07 28.7 4.3 2.6 3 0 0 3 3 3 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28543.1 - 0.0003 21.0 0.1 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO28543.1 - 0.023 14.7 2.5 0.062 13.3 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 EGO28544.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO28544.1 - 0.03 14.9 0.0 0.053 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EGO28544.1 - 0.055 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 EGO28545.1 - 1.1e-08 35.2 0.2 1.1e-08 35.2 0.2 2.9 3 1 1 4 4 4 1 Retrotransposon gag protein Nup192 PF11894.8 EGO28547.1 - 6.6e-235 782.7 0.0 8.8e-235 782.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 STAS_2 PF13466.6 EGO28547.1 - 0.0023 18.3 0.9 0.0095 16.3 0.1 2.5 2 0 0 2 2 2 1 STAS domain Acetyltransf_1 PF00583.25 EGO28548.1 - 4.3e-14 52.8 0.0 5.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO28548.1 - 9.8e-09 35.5 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO28548.1 - 1.2e-08 35.0 0.0 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO28548.1 - 5.9e-08 32.6 0.1 8.6e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGO28548.1 - 4.5e-05 23.5 0.0 6.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGO28548.1 - 0.00042 20.0 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO28548.1 - 0.00068 20.3 0.0 0.00098 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO28548.1 - 0.0036 17.4 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EGO28548.1 - 0.12 12.1 0.2 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ HSP70 PF00012.20 EGO28549.1 - 2.6e-260 864.7 5.8 3e-260 864.6 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO28549.1 - 5.7e-17 61.5 0.8 3.6e-16 58.9 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EGO28549.1 - 0.00066 18.8 0.7 0.044 12.8 0.4 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain FIVAR PF07554.13 EGO28549.1 - 0.0034 18.1 1.6 1.3 9.8 0.3 3.1 2 1 0 2 2 2 1 FIVAR domain Hydantoinase_A PF01968.18 EGO28549.1 - 0.066 12.5 1.0 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase NPV_P10 PF05531.12 EGO28549.1 - 0.14 12.6 1.4 0.62 10.6 0.4 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 EGO28549.1 - 1.8 9.1 8.3 3.6 8.1 0.6 3.3 2 2 1 3 3 3 0 Spectrin repeat AA_permease_2 PF13520.6 EGO28550.1 - 9.8e-66 222.3 59.8 1.2e-65 222.0 59.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO28550.1 - 4.1e-16 58.6 53.3 5.7e-16 58.2 53.3 1.1 1 0 0 1 1 1 1 Amino acid permease COX7B PF05392.11 EGO28550.1 - 0.43 10.3 2.8 0.56 9.9 0.4 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Peptidase_M28 PF04389.17 EGO28551.1 - 2.7e-26 92.5 0.0 4.2e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGO28551.1 - 9.1e-07 28.8 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EGO28551.1 - 0.0051 16.3 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Nicastrin zf-Tim10_DDP PF02953.15 EGO28552.1 - 1.6e-21 75.7 0.6 1.9e-21 75.5 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger 2-Hacid_dh_C PF02826.19 EGO28553.1 - 4.5e-40 136.9 0.0 9.1e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO28553.1 - 1.5e-34 118.6 0.0 2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EGO28553.1 - 0.027 14.5 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EGO28553.1 - 0.17 12.1 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3678 PF12435.8 EGO28553.1 - 0.25 10.7 3.0 0.64 9.4 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) SET PF00856.28 EGO28554.1 - 0.00062 20.2 0.0 0.00089 19.7 0.0 1.3 1 0 0 1 1 1 1 SET domain Amidohydro_2 PF04909.14 EGO28556.1 - 1.5e-20 74.2 0.0 2.7e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EGO28556.1 - 0.001 18.5 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 TatD related DNase DUF89 PF01937.19 EGO28557.1 - 3.7e-98 328.7 0.0 4.8e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 BolA PF01722.18 EGO28557.1 - 2.2e-12 47.1 0.2 4.8e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 BolA-like protein Amino_oxidase PF01593.24 EGO28558.1 - 1.8e-61 208.8 0.1 6.5e-46 157.6 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO28558.1 - 3.2e-10 40.1 0.5 7.1e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO28558.1 - 0.0001 21.7 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO28558.1 - 0.00015 21.3 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO28558.1 - 0.00017 20.9 0.3 0.0048 16.2 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO28558.1 - 0.0013 18.1 0.6 0.0019 17.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGO28558.1 - 0.0014 17.8 0.6 0.0022 17.2 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGO28558.1 - 0.0033 16.7 0.2 0.0085 15.4 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EGO28558.1 - 0.0043 16.7 1.1 0.0083 15.8 0.7 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO28558.1 - 0.0061 17.1 0.2 1.1 9.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO28558.1 - 0.026 13.6 0.1 0.057 12.5 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Herpes_U55 PF06501.11 EGO28558.1 - 0.028 13.2 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U55 protein HI0933_like PF03486.14 EGO28558.1 - 0.23 10.1 0.4 0.48 9.1 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein Orthoreo_P10 PF07204.11 EGO28559.1 - 0.3 11.1 2.7 4.1 7.4 0.6 2.7 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DDE_1 PF03184.19 EGO28561.1 - 2.6e-07 30.5 0.0 4.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO28561.1 - 0.0012 18.6 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 DDE superfamily endonuclease 4HBT PF03061.22 EGO28562.1 - 5e-07 30.0 0.1 0.019 15.3 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Pkinase PF00069.25 EGO28565.1 - 2.6e-48 164.7 0.0 3.7e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28565.1 - 3e-47 161.1 0.0 4.1e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EGO28565.1 - 6.2e-07 29.2 2.1 1.2e-06 28.2 2.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 EGO28565.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGO28565.1 - 0.0034 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO28565.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family C1_2 PF03107.16 EGO28565.1 - 0.018 15.3 0.6 0.042 14.2 0.6 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 EGO28565.1 - 0.042 13.7 4.3 0.091 12.7 4.3 1.5 1 0 0 1 1 1 0 PHD-finger Kinase-like PF14531.6 EGO28565.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Prok-RING_1 PF14446.6 EGO28565.1 - 2.1 8.4 5.1 5.9 6.9 5.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Transp_cyt_pur PF02133.15 EGO28566.1 - 5.2e-106 355.0 36.2 6.1e-106 354.8 36.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_holin_1 PF04531.13 EGO28567.1 - 0.54 10.8 0.1 0.54 10.8 0.1 2.6 2 1 1 3 3 3 0 Bacteriophage holin DUF3810 PF12725.7 EGO28567.1 - 9.2 5.5 9.3 0.3 10.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Dabb PF07876.12 EGO28568.1 - 1.8e-15 57.3 0.1 2e-15 57.2 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Lon_2 PF13337.6 EGO28568.1 - 0.093 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease adh_short_C2 PF13561.6 EGO28570.1 - 1.1e-33 116.7 0.3 1.3e-33 116.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO28570.1 - 9.5e-29 100.2 0.0 1.2e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO28570.1 - 8.8e-05 22.5 0.1 0.00026 21.0 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO28570.1 - 0.031 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PEMT PF04191.13 EGO28571.1 - 1.4e-32 112.2 5.8 1.8e-32 111.9 2.8 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase F-box-like PF12937.7 EGO28572.1 - 3.9e-08 33.0 3.5 1.1e-07 31.6 3.5 1.9 1 0 0 1 1 1 1 F-box-like Retrotrans_gag PF03732.17 EGO28573.1 - 3.3e-06 27.3 1.6 3.3e-06 27.3 1.6 2.5 2 2 1 3 3 3 1 Retrotransposon gag protein M64_N PF16217.5 EGO28573.1 - 0.042 13.4 0.3 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Peptidase M64 N-terminus DUF4939 PF16297.5 EGO28573.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) ECH_1 PF00378.20 EGO28573.1 - 0.066 12.5 6.2 1.9 7.7 0.0 3.2 3 1 1 4 4 4 0 Enoyl-CoA hydratase/isomerase Plavaka PF18759.1 EGO28576.1 - 5e-40 137.7 0.1 5e-40 137.7 0.1 2.1 2 0 0 2 2 2 1 Plavaka transposase FrhB_FdhB_C PF04432.13 EGO28576.1 - 0.16 11.8 2.2 0.46 10.3 0.1 2.4 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus UQ_con PF00179.26 EGO28577.1 - 4.6e-39 133.3 0.0 6.2e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC1 PF03109.16 EGO28579.1 - 1.4e-28 99.5 0.0 2.2e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGO28579.1 - 0.0016 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Peptidase_S28 PF05577.12 EGO28580.1 - 3.8e-44 151.2 1.0 7.6e-44 150.2 1.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGO28580.1 - 0.00029 20.4 0.2 0.0006 19.4 0.2 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 EGO28583.1 - 6.6e-50 170.2 0.0 1.2e-49 169.3 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGO28583.1 - 0.00045 19.7 0.1 0.00076 19.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_3_C PF01915.22 EGO28584.1 - 2.2e-53 181.2 0.0 4.3e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO28584.1 - 2e-39 135.8 0.1 3.7e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO28584.1 - 6.8e-20 71.0 0.0 1.7e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain V-SNARE_C PF12352.8 EGO28585.1 - 0.00058 20.1 7.0 0.14 12.4 0.4 2.8 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Atg14 PF10186.9 EGO28585.1 - 4.7 6.2 8.5 5.2 6.1 7.7 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EGO28585.1 - 7.1 6.7 6.0 17 5.5 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NACHT PF05729.12 EGO28586.1 - 4.3e-09 36.5 0.0 1.1e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain HNH_2 PF13391.6 EGO28586.1 - 1.4e-07 31.6 0.0 3.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease AAA_16 PF13191.6 EGO28586.1 - 9.6e-06 26.1 0.0 6.8e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EGO28586.1 - 2.6e-05 24.3 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGO28586.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGO28586.1 - 0.0081 15.4 0.0 0.027 13.6 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 EGO28586.1 - 0.11 11.7 1.0 0.44 9.7 0.2 2.0 1 1 0 2 2 2 0 KAP family P-loop domain AAA PF00004.29 EGO28586.1 - 0.14 12.6 0.0 0.91 9.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGO28586.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.22 EGO28587.1 - 4e-29 100.2 0.1 1.1e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TnsE_C PF18623.1 EGO28587.1 - 0.23 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 TnsE C-terminal domain AMP-binding PF00501.28 EGO28588.1 - 1.1e-73 248.3 0.0 1.6e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGO28588.1 - 1.3e-12 47.2 1.0 6e-12 45.0 0.8 2.1 2 1 0 2 2 2 1 Condensation domain Methyltransf_25 PF13649.6 EGO28588.1 - 1.3e-11 45.0 0.0 1.1e-10 42.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGO28588.1 - 3.9e-11 43.1 0.0 2.1e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EGO28588.1 - 7.2e-11 42.7 0.0 9e-10 39.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO28588.1 - 1.2e-10 41.8 0.0 9e-10 39.1 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO28588.1 - 5.5e-09 36.0 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 EGO28588.1 - 5.5e-08 33.7 2.1 5.7e-05 24.0 0.0 3.1 3 0 0 3 3 2 2 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 EGO28588.1 - 9.6e-08 32.0 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGO28588.1 - 1.1e-06 28.5 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EGO28588.1 - 0.0001 21.9 0.0 0.00053 19.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain CheR PF01739.18 EGO28588.1 - 0.0018 17.8 0.2 0.018 14.5 0.0 2.6 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain MetW PF07021.12 EGO28588.1 - 0.023 14.3 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 EGO28588.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 EGO28588.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGO28588.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sugar_tr PF00083.24 EGO28589.1 - 6.3e-101 338.5 15.7 7.2e-101 338.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO28589.1 - 1.1e-29 103.5 25.7 7.9e-19 67.8 0.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGO28589.1 - 0.00078 17.8 1.7 0.00078 17.8 1.7 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MR_MLE_C PF13378.6 EGO28590.1 - 5.1e-41 140.7 0.0 6.8e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGO28590.1 - 9.2e-11 42.0 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.29 EGO28592.1 - 4.1e-54 182.6 0.0 1.3e-43 148.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EGO28592.1 - 1.6e-24 86.1 1.3 5.1e-24 84.5 1.3 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EGO28592.1 - 1.4e-14 53.6 2.1 7.5e-10 38.5 0.1 2.9 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EGO28592.1 - 2.6e-07 31.2 7.2 0.016 15.6 0.0 5.1 3 2 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 EGO28592.1 - 6e-06 26.3 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO28592.1 - 0.0003 21.3 0.1 0.24 12.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 EGO28592.1 - 0.00093 19.3 0.0 0.068 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGO28592.1 - 0.0014 18.4 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 EGO28592.1 - 0.0016 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO28592.1 - 0.002 18.1 0.4 0.66 10.0 0.0 3.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO28592.1 - 0.0027 18.0 1.1 1 9.6 0.1 4.1 2 2 0 2 2 2 1 AAA domain TsaE PF02367.17 EGO28592.1 - 0.0034 17.4 0.1 0.61 10.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGO28592.1 - 0.0081 16.5 0.0 0.66 10.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 EGO28592.1 - 0.011 15.6 0.7 5.6 6.8 0.0 3.8 3 1 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 EGO28592.1 - 0.013 15.7 0.0 0.085 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EGO28592.1 - 0.016 15.2 0.4 0.16 12.0 0.1 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain NB-ARC PF00931.22 EGO28592.1 - 0.018 14.2 0.0 4.3 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EGO28592.1 - 0.022 14.4 0.0 0.27 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 EGO28592.1 - 0.024 13.9 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EGO28592.1 - 0.039 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EGO28592.1 - 0.097 12.2 0.0 16 5.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGO28592.1 - 0.1 11.9 0.1 0.75 9.1 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 EGO28592.1 - 0.11 12.4 0.4 14 5.5 0.1 3.1 3 1 0 3 3 2 0 Bacterial dnaA protein AAA_3 PF07726.11 EGO28592.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGO28592.1 - 0.21 12.0 1.2 0.37 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain p450 PF00067.22 EGO28594.1 - 3.6e-53 180.9 0.0 4.4e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 EGO28595.1 - 6.7e-37 126.8 1.2 6.7e-37 126.8 1.2 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO28595.1 - 7.4e-33 113.8 3.2 7.4e-33 113.8 3.2 3.1 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO28595.1 - 1e-19 71.6 0.0 8.4e-10 39.3 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO28595.1 - 5.1e-17 61.7 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO28595.1 - 1.1e-07 31.9 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO28595.1 - 0.00061 20.2 0.0 0.27 11.6 0.0 2.8 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO28595.1 - 0.034 13.8 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus PseudoU_synth_2 PF00849.22 EGO28596.1 - 6.5e-27 94.6 0.0 8.8e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Y_Y_Y PF07495.13 EGO28597.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Y_Y_Y domain E1-E2_ATPase PF00122.20 EGO28598.1 - 2.4e-39 134.7 3.3 3.5e-39 134.2 1.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO28598.1 - 2.3e-26 92.6 6.4 2.3e-26 92.6 6.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO28598.1 - 7.1e-20 72.2 0.5 5.1e-10 40.0 0.0 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO28598.1 - 2.1e-18 66.2 0.0 3.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO28598.1 - 9.4e-08 32.1 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO28598.1 - 0.00071 20.0 0.1 0.45 10.9 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase P16-Arc PF04699.14 EGO28599.1 - 1.1e-51 175.2 0.0 1.2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 EGO28599.1 - 0.014 15.7 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF2711 PF10924.8 EGO28599.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) KDZ PF18758.1 EGO28600.1 - 0.49 10.0 3.9 0.46 10.1 0.1 2.1 1 1 1 2 2 2 0 Kyakuja-Dileera-Zisupton transposase BAR PF03114.18 EGO28601.1 - 2.1e-41 142.2 14.0 2.8e-41 141.8 14.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGO28601.1 - 3.1e-15 55.5 0.5 6.6e-15 54.4 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGO28601.1 - 1.7e-12 47.0 0.1 3.1e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO28601.1 - 1.5e-09 37.4 0.0 2.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 EGO28601.1 - 2.5e-06 27.4 8.4 4.7e-06 26.5 8.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family SWIB PF02201.18 EGO28602.1 - 2.5e-23 81.7 0.0 5.1e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain GPS2_interact PF15784.5 EGO28602.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain EutA PF06277.11 EGO28602.1 - 0.13 11.0 0.0 0.26 10.1 0.0 1.4 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA DUF3638 PF12340.8 EGO28603.1 - 7.9e-90 300.1 0.4 1.4e-89 299.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGO28603.1 - 3.4e-16 58.3 2.3 3.7e-16 58.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) DUF1365 PF07103.11 EGO28606.1 - 8.8e-69 231.8 0.0 1.3e-68 231.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) SRI PF08236.11 EGO28607.1 - 2.8e-18 65.9 14.9 2.8e-18 65.9 14.9 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EGO28607.1 - 1.2e-14 55.1 0.3 1.2e-14 55.1 0.3 3.5 2 2 0 2 2 2 1 SET domain AWS PF17907.1 EGO28607.1 - 1.6e-13 50.5 8.4 1.6e-13 50.5 8.4 1.8 2 0 0 2 2 2 1 AWS domain ACC_epsilon PF13822.6 EGO28607.1 - 0.022 15.4 3.6 0.086 13.5 3.6 2.0 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Med26 PF08711.11 EGO28607.1 - 0.035 14.1 0.3 0.035 14.1 0.3 3.4 4 0 0 4 4 4 0 TFIIS helical bundle-like domain RNA_pol_I_A49 PF06870.12 EGO28608.1 - 6.7e-116 387.3 0.6 7.7e-116 387.1 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.25 EGO28609.1 - 4.2e-38 131.2 0.0 5.4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28609.1 - 7e-30 104.2 0.0 9.9e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO28609.1 - 2.9e-06 26.8 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO28609.1 - 0.036 14.0 0.1 0.7 9.8 0.1 2.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGO28609.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 BP28CT PF08146.12 EGO28610.1 - 2.7e-27 95.6 1.2 2.7e-27 95.6 1.2 2.6 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EGO28610.1 - 5e-16 59.1 5.8 9.6e-16 58.2 0.3 4.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 DUF5455 PF17537.2 EGO28612.1 - 0.052 14.0 0.8 0.19 12.2 0.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5455) DUF2569 PF10754.9 EGO28612.1 - 3.6 8.0 10.1 0.2 12.1 1.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) Polyketide_cyc2 PF10604.9 EGO28613.1 - 3.1e-06 27.5 1.2 6.5e-06 26.5 1.2 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EGO28613.1 - 0.018 15.2 1.6 0.043 14.0 1.6 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport VF530 PF09905.9 EGO28614.1 - 0.48 10.6 1.5 1.1 9.5 0.9 1.9 2 0 0 2 2 2 0 DNA-binding protein VF530 Period_C PF12114.8 EGO28615.1 - 0.0026 17.4 0.2 0.0032 17.1 0.2 1.0 1 0 0 1 1 1 1 Period protein 2/3C-terminal region RSN1_TM PF13967.6 EGO28617.1 - 0.0058 16.4 0.1 0.0062 16.3 0.1 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Nexin_C PF08628.12 EGO28618.1 - 0.018 15.6 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Sorting nexin C terminal Sec_GG PF07549.14 EGO28619.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif CytochromB561_N PF09786.9 EGO28621.1 - 0.0019 17.3 0.0 0.002 17.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal ECF_trnsprt PF12822.7 EGO28622.1 - 0.011 15.9 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Rhv PF00073.20 EGO28622.1 - 0.064 12.9 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 picornavirus capsid protein BAG PF02179.16 EGO28623.1 - 0.00036 20.9 1.9 0.0019 18.6 0.1 2.6 3 0 0 3 3 3 1 BAG domain zf-C2H2_assoc PF16606.5 EGO28623.1 - 0.038 14.2 3.2 0.075 13.3 3.2 1.5 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers Nup54_57_C PF18570.1 EGO28623.1 - 2.1 8.0 0.0 2.1 8.0 0.0 2.9 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain p450 PF00067.22 EGO28626.1 - 3.1e-53 181.2 0.0 2.1e-44 152.1 0.1 2.4 2 1 1 3 3 3 2 Cytochrome P450 p450 PF00067.22 EGO28627.1 - 1e-62 212.4 0.0 1.5e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.6 EGO28628.1 - 2.1e-24 85.5 0.0 4.1e-10 40.0 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO28628.1 - 6.2e-21 74.2 0.0 9.9e-08 32.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGO28628.1 - 5.7e-19 67.7 0.0 6.6e-05 23.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGO28628.1 - 8.7e-19 67.9 0.0 7.4e-12 45.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO28628.1 - 2.4e-16 58.1 0.0 0.00036 20.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat PEGA PF08308.11 EGO28628.1 - 0.14 12.0 0.0 17 5.4 0.0 2.9 3 0 0 3 3 3 0 PEGA domain AAA_22 PF13401.6 EGO28629.1 - 0.00043 20.6 0.0 0.00071 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGO28629.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO28629.1 - 0.0033 17.8 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGO28629.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EGO28629.1 - 0.016 15.7 0.0 0.047 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO28629.1 - 0.021 15.2 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EGO28629.1 - 0.023 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 EGO28629.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FAD_binding_1 PF00667.20 EGO28631.1 - 2e-37 128.9 0.0 3.1e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGO28631.1 - 2.5e-27 95.9 0.0 5e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGO28631.1 - 3.2e-10 40.6 0.0 6.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SNase PF00565.17 EGO28632.1 - 1.1e-18 67.7 0.0 2.1e-18 66.8 0.0 1.5 2 0 0 2 2 2 1 Staphylococcal nuclease homologue SNF2_N PF00176.23 EGO28634.1 - 2.1e-60 204.3 0.3 3.3e-60 203.7 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO28634.1 - 1.3e-18 67.4 0.0 3.3e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO28634.1 - 1.3e-06 28.6 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 EGO28634.1 - 5.7e-05 23.0 2.0 0.00016 21.6 2.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger SWI2_SNF2 PF18766.1 EGO28634.1 - 0.00011 21.9 0.1 0.00019 21.2 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-C3HC4 PF00097.25 EGO28634.1 - 0.00012 21.9 2.5 0.00012 21.9 2.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO28634.1 - 0.00026 21.1 1.5 0.00067 19.8 1.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 EGO28634.1 - 0.00053 19.3 0.0 0.00092 18.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_2 PF13923.6 EGO28634.1 - 0.00061 19.6 3.6 0.00061 19.6 3.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO28634.1 - 0.0077 16.5 2.3 0.0077 16.5 2.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGO28634.1 - 0.047 13.6 6.3 0.18 11.8 6.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGO28634.1 - 0.062 13.2 6.5 0.025 14.4 2.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ada_Zn_binding PF02805.16 EGO28634.1 - 0.082 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada zf-RING_4 PF14570.6 EGO28634.1 - 0.2 11.5 3.9 12 5.8 0.1 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF4238 PF14022.6 EGO28635.1 - 1.5e-27 96.8 0.0 2e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF3638 PF12340.8 EGO28636.1 - 3.1e-91 304.7 0.3 6.7e-91 303.6 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGO28636.1 - 1.4e-16 59.6 0.1 2.7e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) IL17R_fnIII_D1 PF16556.5 EGO28636.1 - 0.2 11.3 1.4 5.7 6.6 0.1 3.2 3 0 0 3 3 3 0 Interleukin-17 receptor, fibronectin-III-like domain 1 Complex1_LYR PF05347.15 EGO28637.1 - 9.1e-10 38.4 0.2 1.6e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO28637.1 - 0.011 16.4 0.1 0.015 16.1 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like PPR_2 PF13041.6 EGO28641.1 - 5.2e-17 61.8 0.0 1.5e-05 25.1 0.0 4.7 4 0 0 4 4 4 3 PPR repeat family PPR_long PF17177.4 EGO28641.1 - 0.00025 20.5 0.1 0.22 10.9 0.0 3.0 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGO28641.1 - 0.00068 19.7 0.0 0.039 14.2 0.0 3.7 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 EGO28641.1 - 0.42 10.4 1.1 3.7 7.3 0.0 3.1 3 0 0 3 3 3 0 PPR repeat RRM_1 PF00076.22 EGO28642.1 - 5.6e-15 54.9 0.0 7.6e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO28642.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Lyase_1 PF00206.20 EGO28644.1 - 2e-21 76.7 0.0 2.8e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGO28644.1 - 1e-18 67.6 0.0 3e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 EGO28644.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Pkinase PF00069.25 EGO28646.1 - 9.6e-65 218.6 0.0 1.2e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28646.1 - 8.5e-38 130.1 0.0 1.2e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO28646.1 - 8.6e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO28646.1 - 0.00086 18.3 0.5 0.0013 17.7 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGO28646.1 - 0.0013 18.4 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGO28646.1 - 0.011 15.7 0.7 0.041 13.8 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.11 EGO28646.1 - 0.044 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.9 EGO28646.1 - 0.045 13.3 0.3 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EGO28646.1 - 0.52 9.0 5.9 2.1 7.0 5.9 1.9 1 1 0 1 1 1 0 Fungal protein kinase KA1 PF02149.19 EGO28647.1 - 3e-05 23.7 0.1 7.4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Kinase associated domain 1 Integrase_H2C2 PF17921.1 EGO28648.1 - 7.4e-08 32.4 1.9 1.4e-07 31.5 1.9 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain SKN1 PF03935.15 EGO28649.1 - 3.5e-185 616.2 0.6 3.9e-185 616.0 0.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HEM4 PF02602.15 EGO28650.1 - 4.4e-35 121.1 0.0 5e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PTPS PF01242.19 EGO28650.1 - 0.085 12.8 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase SRA1 PF07304.11 EGO28651.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Mito_carr PF00153.27 EGO28652.1 - 1.3e-62 207.7 3.6 1.2e-20 73.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO28652.1 - 1.9 7.6 3.9 5 6.2 0.4 2.9 1 1 1 3 3 3 0 Gammaproteobacterial serine protease DUF4939 PF16297.5 EGO28654.1 - 0.042 13.7 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Zea_mays_MuDR PF05928.11 EGO28655.1 - 0.045 13.4 0.1 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Sec_GG PF07549.14 EGO28658.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Retrotran_gag_2 PF14223.6 EGO28660.1 - 0.008 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO28660.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DUF496 PF04363.12 EGO28662.1 - 0.044 13.8 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF1664 PF07889.12 EGO28662.1 - 0.055 13.5 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tht1 PF04163.12 EGO28662.1 - 0.071 11.9 0.0 0.084 11.6 0.0 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein AAA_22 PF13401.6 EGO28663.1 - 0.00018 21.8 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGO28663.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EGO28663.1 - 0.00064 19.7 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EGO28663.1 - 0.00087 18.5 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGO28663.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGO28663.1 - 0.0086 15.5 0.0 0.058 12.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 EGO28663.1 - 0.024 14.8 0.0 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EGO28663.1 - 0.043 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 EGO28663.1 - 0.049 14.0 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA PF00004.29 EGO28663.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGO28663.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGO28663.1 - 0.13 12.2 0.4 5.3 7.1 0.0 2.5 1 1 2 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DDE_1 PF03184.19 EGO28665.1 - 6.5e-16 58.5 0.0 1.1e-15 57.7 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease SL4P PF17618.2 EGO28665.1 - 0.01 15.9 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein DDE_3 PF13358.6 EGO28665.1 - 0.019 14.8 0.0 0.047 13.4 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease Macoilin PF09726.9 EGO28666.1 - 0.016 13.8 5.5 0.017 13.7 5.5 1.0 1 0 0 1 1 1 0 Macoilin family Retrotran_gag_2 PF14223.6 EGO28667.1 - 8.2e-11 41.7 0.2 1.1e-10 41.4 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EGO28668.1 - 1.6e-08 34.2 3.0 3.6e-08 33.1 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28668.1 - 9.2e-08 32.3 0.3 3.4e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 EGO28668.1 - 0.17 11.6 0.9 0.36 10.6 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Ras PF00071.22 EGO28670.1 - 3.9e-50 169.6 0.0 4.6e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO28670.1 - 5.8e-23 81.4 0.0 8.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO28670.1 - 5.1e-06 26.0 0.0 8.3e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO28670.1 - 0.028 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGO28670.1 - 0.099 13.0 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Pro_CA PF00484.19 EGO28671.1 - 7.1e-38 130.4 0.3 1.9e-37 129.0 0.3 1.6 1 1 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 EGO28672.1 - 1.1e-30 106.9 0.0 3.6e-30 105.3 0.0 1.8 1 1 0 1 1 1 1 Carbonic anhydrase RINGv PF12906.7 EGO28675.1 - 8.3e-07 29.0 7.2 1.7e-06 28.1 7.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EGO28675.1 - 0.0037 17.5 6.9 0.0064 16.8 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EGO28675.1 - 0.048 13.8 3.3 0.095 12.9 3.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD_4 PF16866.5 EGO28675.1 - 0.24 11.5 6.6 0.43 10.7 6.6 1.4 1 0 0 1 1 1 0 PHD-finger eIF2_C PF09173.11 EGO28676.1 - 2e-34 117.7 0.7 5e-34 116.4 0.7 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGO28676.1 - 7e-21 74.7 1.6 9.9e-20 70.9 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGO28676.1 - 6.8e-12 45.6 1.8 1e-11 45.1 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EGO28676.1 - 0.0033 17.3 0.3 0.046 13.6 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGO28676.1 - 0.017 15.1 1.5 0.028 14.4 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGO28676.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF397 PF04149.12 EGO28677.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF397) zf-primase PF09329.11 EGO28679.1 - 1.2e-18 66.6 3.5 2.1e-18 65.8 3.5 1.5 1 0 0 1 1 1 1 Primase zinc finger FlxA PF14282.6 EGO28679.1 - 0.028 14.4 0.7 0.028 14.4 0.7 2.2 2 0 0 2 2 2 0 FlxA-like protein RasGEF PF00617.19 EGO28680.1 - 8e-27 94.6 0.3 6.1e-26 91.7 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGO28680.1 - 1.2e-09 38.3 1.3 3.8e-09 36.7 1.3 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif UCH PF00443.29 EGO28681.1 - 1e-37 130.0 0.0 1.7e-37 129.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO28681.1 - 6.7e-11 42.3 0.8 9.2e-09 35.3 0.8 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGO28681.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family HECA PF15353.6 EGO28681.1 - 0.16 12.2 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Headcase protein family homologue Bap31 PF05529.12 EGO28682.1 - 1.9e-45 154.0 5.9 3.4e-45 153.2 5.9 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGO28682.1 - 1.2e-11 44.4 7.8 1.2e-11 44.4 7.8 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cortexin PF11057.8 EGO28682.1 - 0.024 14.5 0.2 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Cortexin of kidney Ntox15 PF15604.6 EGO28682.1 - 0.041 14.0 4.2 0.067 13.3 4.2 1.3 1 0 0 1 1 1 0 Novel toxin 15 CLN3 PF02487.17 EGO28682.1 - 1.6 7.7 6.0 0.18 10.8 0.5 1.8 2 0 0 2 2 2 0 CLN3 protein SET PF00856.28 EGO28684.1 - 1.9e-12 47.9 0.0 3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 EGO28684.1 - 3.3e-05 23.9 0.0 9.2e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 HTH-like domain Sorting_nexin PF03700.13 EGO28684.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain p450 PF00067.22 EGO28685.1 - 2.3e-72 244.2 0.0 5.6e-72 243.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DNA_pol_A_exo1 PF01612.20 EGO28686.1 - 2.7e-18 66.3 0.0 3.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.20 EGO28687.1 - 4.3e-16 59.1 0.0 5.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Glyco_hydro_18 PF00704.28 EGO28688.1 - 4.5e-26 92.3 0.3 1.8e-25 90.3 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.22 EGO28690.1 - 6.2e-66 223.0 0.0 1.8e-65 221.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 EGO28691.1 - 2.1e-13 50.0 0.2 2.1e-13 50.0 0.2 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain G-alpha PF00503.20 EGO28693.1 - 3.1e-110 368.7 0.0 3.6e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO28693.1 - 1.5e-10 40.8 0.2 2.2e-07 30.5 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 EGO28693.1 - 0.0028 17.9 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGO28693.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Zeta_toxin PF06414.12 EGO28693.1 - 0.0087 15.4 0.1 0.084 12.1 0.0 2.4 3 0 0 3 3 3 1 Zeta toxin Na_H_Exchanger PF00999.21 EGO28694.1 - 1.8e-73 247.5 33.6 2.3e-73 247.2 33.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 60KD_IMP PF02096.20 EGO28695.1 - 6.9e-15 55.3 5.3 9.2e-15 54.9 5.3 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2076 PF09849.9 EGO28697.1 - 0.23 11.5 0.3 0.39 10.7 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MerE PF05052.12 EGO28699.1 - 0.16 11.9 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 MerE protein EF1_GNE PF00736.19 EGO28700.1 - 1.5e-31 108.4 0.8 2.7e-31 107.6 0.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGO28700.1 - 2.6e-12 46.9 7.8 2.6e-12 46.9 7.8 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 EGO28700.1 - 0.0073 16.5 0.6 0.19 12.0 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO28700.1 - 0.046 13.7 0.0 0.35 10.9 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO28700.1 - 0.057 13.6 0.2 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 EGO28700.1 - 0.063 13.8 0.8 0.097 13.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) RE_NgoPII PF09521.10 EGO28700.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease Cnd2 PF05786.14 EGO28700.1 - 0.19 10.3 2.7 0.26 9.9 2.7 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 IcmF-related PF06761.12 EGO28705.1 - 0.063 12.8 0.3 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing ANAPC4_WD40 PF12894.7 EGO28708.1 - 8.4e-13 48.4 0.5 1.4e-06 28.5 0.1 4.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO28708.1 - 1.3e-08 35.3 15.9 6.1e-06 26.9 0.2 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 EGO28708.1 - 0.0003 20.7 0.0 0.77 9.6 0.0 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EGO28708.1 - 0.022 13.1 0.0 0.035 12.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz LPD23 PF18838.1 EGO28709.1 - 0.39 10.5 2.9 0.63 9.8 2.9 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 MFS_1 PF07690.16 EGO28710.1 - 2.6e-18 66.1 18.4 1.6e-16 60.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGO28710.1 - 0.26 10.6 14.4 1.1 8.5 3.7 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Saf_2TM PF18303.1 EGO28710.1 - 0.67 9.5 0.0 0.67 9.5 0.0 2.8 2 2 0 3 3 3 0 SAVED-fused 2TM effector domain DUF2892 PF11127.8 EGO28710.1 - 4.9 7.3 16.7 1.3 9.1 0.2 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF2892) Transgly_assoc PF04226.13 EGO28710.1 - 9 6.6 10.0 0.26 11.6 0.9 3.0 3 0 0 3 3 3 0 Transglycosylase associated protein PHD PF00628.29 EGO28711.1 - 5.6e-07 29.3 9.5 9.9e-07 28.6 9.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGO28711.1 - 0.038 13.5 7.7 0.082 12.5 7.7 1.5 1 0 0 1 1 1 0 PHD-finger SET PF00856.28 EGO28711.1 - 0.05 14.0 0.0 0.16 12.3 0.0 1.9 1 1 0 1 1 1 0 SET domain Sod_Fe_C PF02777.18 EGO28712.1 - 5.9e-36 122.7 0.2 1e-35 121.9 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGO28712.1 - 3.6e-31 107.5 3.2 3.6e-31 107.5 3.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ocnus PF05005.15 EGO28712.1 - 0.089 12.9 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) NACHT PF05729.12 EGO28713.1 - 1.8e-09 37.7 0.0 4.9e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO28713.1 - 0.00012 22.5 0.0 0.00078 19.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO28713.1 - 0.0019 18.5 0.0 0.0061 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EGO28713.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 EGO28713.1 - 0.024 15.1 0.0 0.26 11.7 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGO28713.1 - 0.071 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EGO28713.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGO28713.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Terpene_synth_C PF03936.16 EGO28715.1 - 1.7e-09 37.4 0.0 3.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 EGO28715.1 - 4.7e-05 22.4 0.1 7.1e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Chibby PF14645.6 EGO28715.1 - 0.041 14.3 0.2 0.079 13.4 0.2 1.5 1 0 0 1 1 1 0 Chibby family p450 PF00067.22 EGO28716.1 - 1.4e-62 212.0 0.0 1.7e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GP52 PF17468.2 EGO28716.1 - 0.096 12.8 0.0 2.4 8.4 0.0 2.6 3 0 0 3 3 3 0 Phage gene product 52 Bac_rhamnosid6H PF17389.2 EGO28717.1 - 2.6e-17 63.1 0.7 4.4e-17 62.4 0.7 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EGO28717.1 - 1.9e-09 37.2 0.0 4.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 EGO28717.1 - 0.0048 15.8 0.5 0.0079 15.1 0.5 1.2 1 0 0 1 1 1 1 Trehalase F-box-like PF12937.7 EGO28718.1 - 9.2e-06 25.5 0.0 4.4e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 F-box-like DUF3638 PF12340.8 EGO28719.1 - 1.7e-91 305.6 0.2 3.2e-91 304.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGO28719.1 - 4.2e-16 58.0 0.1 9e-16 57.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF4675 PF15720.5 EGO28719.1 - 0.0033 17.3 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4675) PigN PF04987.14 EGO28720.1 - 3.3e-131 438.3 39.5 4e-131 438.0 39.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGO28720.1 - 2.9e-10 40.3 2.1 2.8e-07 30.5 1.5 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGO28720.1 - 9.7e-05 21.9 0.1 0.0005 19.5 0.1 1.9 2 0 0 2 2 2 1 Sulfatase Peroxidase_2 PF01328.17 EGO28721.1 - 4.7e-50 170.7 0.0 5.7e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Mito_carr PF00153.27 EGO28722.1 - 4.4e-59 196.4 1.3 7.9e-22 77.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.12 EGO28723.1 - 9.7e-12 45.1 1.0 4e-10 40.0 1.0 2.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 EGO28723.1 - 0.046 13.7 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain OCRL_clath_bd PF16726.5 EGO28723.1 - 0.094 12.9 0.0 2.8 8.2 0.0 2.0 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain EAP30 PF04157.16 EGO28726.1 - 1.2e-41 142.6 0.0 1.5e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EGO28726.1 - 8.8e-18 64.3 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 EGO28726.1 - 0.025 13.9 13.1 0.23 10.8 3.2 2.8 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.7 EGO28726.1 - 0.033 14.2 4.4 0.22 11.6 0.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 EGO28726.1 - 0.073 12.5 8.2 0.04 13.3 1.4 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EGO28726.1 - 0.21 11.7 7.6 0.62 10.2 0.4 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger STE PF02200.16 EGO28730.1 - 9.7e-41 138.6 0.1 1.3e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EGO28731.1 - 1.5e-10 41.0 14.2 1.6e-05 25.0 2.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO28731.1 - 2.9e-08 33.8 7.8 2.9e-08 33.8 7.8 2.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO28731.1 - 2.2e-07 31.2 12.9 0.00035 21.1 2.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO28731.1 - 7.3e-05 23.0 7.3 0.022 15.0 2.6 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO28731.1 - 0.0024 18.2 8.3 0.06 13.7 3.5 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EGO28731.1 - 0.0048 17.3 9.9 0.0072 16.8 1.3 2.1 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC_2 PF13696.6 EGO28731.1 - 0.095 12.5 1.9 0.095 12.5 1.9 1.7 2 0 0 2 2 2 0 Zinc knuckle zf_C2H2_ZHX PF18387.1 EGO28731.1 - 0.99 9.1 6.7 2.8 7.7 0.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 EGO28731.1 - 1 9.4 14.7 0.35 10.9 3.3 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 EGO28731.1 - 1.6 8.8 8.6 3.6 7.7 1.8 2.1 1 1 1 2 2 2 0 BED zinc finger DUF1687 PF07955.11 EGO28733.1 - 3.2e-21 76.1 0.0 3.9e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Phosphorylase PF00343.20 EGO28736.1 - 2.3e-292 971.6 0.0 2.7e-292 971.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase RRM_1 PF00076.22 EGO28739.1 - 4.2e-71 234.7 0.1 1.3e-17 63.4 0.0 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO28739.1 - 6.3e-08 32.4 0.0 0.0004 20.2 0.0 4.2 5 0 0 5 5 5 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EGO28739.1 - 0.00013 22.2 0.7 26 5.0 0.0 5.8 5 1 1 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 EGO28739.1 - 0.00019 21.4 0.0 7.9 6.6 0.0 5.0 6 0 0 6 6 6 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EGO28739.1 - 0.00039 20.3 0.4 24 4.7 0.0 5.1 5 2 1 6 6 6 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 EGO28739.1 - 0.0015 18.6 0.1 1.7 8.7 0.0 4.3 5 0 0 5 5 5 1 RNA binding motif Limkain-b1 PF11608.8 EGO28739.1 - 0.0065 16.5 0.0 6.6 6.9 0.0 3.6 2 0 0 2 2 2 2 Limkain b1 DUF3343 PF11823.8 EGO28739.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Prefoldin PF02996.17 EGO28740.1 - 1.3e-26 92.9 2.8 4.5e-25 87.9 1.4 2.5 1 1 1 2 2 2 1 Prefoldin subunit PAC2 PF09754.9 EGO28740.1 - 0.0093 16.0 0.2 0.033 14.2 0.2 1.7 1 1 1 2 2 2 1 PAC2 family Prefoldin_2 PF01920.20 EGO28740.1 - 0.021 14.8 0.9 0.5 10.3 0.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit SID-1_RNA_chan PF13965.6 EGO28740.1 - 0.032 12.7 0.2 0.039 12.4 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Syntaxin-6_N PF09177.11 EGO28740.1 - 0.13 12.9 4.4 3.3 8.3 0.4 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sugar_tr PF00083.24 EGO28741.1 - 2.6e-15 56.3 20.1 4.6e-14 52.1 5.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO28741.1 - 8e-14 51.3 48.6 5.8e-10 38.6 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 EGO28745.1 - 0.00021 21.6 3.1 0.00031 21.1 2.7 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Cyt_b-c1_8 PF10890.8 EGO28745.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 MitoNEET_N PF10660.9 EGO28745.1 - 0.11 12.6 3.6 8.4 6.5 0.1 2.7 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus SNF2_N PF00176.23 EGO28746.1 - 7.5e-50 169.6 0.0 1.9e-49 168.3 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EGO28746.1 - 1.7e-06 28.2 11.6 3.9e-06 27.1 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO28746.1 - 2.4e-06 27.3 8.9 4.1e-06 26.5 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO28746.1 - 4.4e-06 26.5 9.5 9.2e-06 25.4 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO28746.1 - 4.4e-05 23.2 10.5 8.3e-05 22.3 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EGO28746.1 - 4.8e-05 23.7 0.1 0.00015 22.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EGO28746.1 - 9.5e-05 22.3 11.1 0.00017 21.5 11.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO28746.1 - 0.00034 20.4 8.2 0.00063 19.5 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGO28746.1 - 0.0006 20.1 6.1 0.0014 18.9 6.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGO28746.1 - 0.054 13.5 6.1 0.17 11.9 6.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGO28746.1 - 0.063 12.9 7.5 0.12 12.0 7.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGO28746.1 - 0.13 12.3 5.3 0.53 10.4 5.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger VWC PF00093.18 EGO28746.1 - 2.2 8.7 7.8 4.2 7.8 7.8 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain zf-Nse PF11789.8 EGO28746.1 - 4.5 7.2 5.4 18 5.2 4.5 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EGO28746.1 - 5.5 7.2 9.9 11 6.3 9.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-binding PF00249.31 EGO28747.1 - 2.3e-19 69.3 0.5 1.6e-10 41.0 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO28747.1 - 5.9e-14 52.1 0.1 2e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGO28747.1 - 6.1e-05 23.0 0.2 0.29 11.2 0.0 2.3 2 0 0 2 2 2 2 SLIDE PCI PF01399.27 EGO28748.1 - 4.1e-10 40.1 0.2 2e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain F-box-like PF12937.7 EGO28749.1 - 5.6e-06 26.1 0.4 1.8e-05 24.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO28749.1 - 0.049 13.5 1.1 0.27 11.2 0.0 2.7 2 1 0 2 2 2 0 F-box domain ICMT PF04140.14 EGO28750.1 - 7.8e-13 48.7 0.3 2.1e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO28750.1 - 3.6e-12 46.6 0.4 1.2e-11 44.9 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGO28750.1 - 0.0001 21.2 0.2 0.00013 20.9 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGO28750.1 - 0.11 12.0 0.6 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) ICMT PF04140.14 EGO28751.1 - 5.9e-13 49.1 1.3 1e-12 48.3 0.1 2.1 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGO28751.1 - 1.8e-11 44.4 0.5 6.1e-11 42.7 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EGO28751.1 - 2.5e-06 26.5 0.4 3.5e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGO28751.1 - 0.04 13.4 0.3 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) AP_endonuc_2 PF01261.24 EGO28752.1 - 1.2e-29 103.2 0.0 1.9e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel STE3 PF02076.15 EGO28753.1 - 1.2e-118 395.6 18.2 1.5e-118 395.3 18.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 EGO28753.1 - 0.13 12.1 0.3 0.31 10.9 0.1 1.7 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor HAD_2 PF13419.6 EGO28754.1 - 1.5e-07 31.7 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO28754.1 - 3.3e-06 27.6 0.0 5.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO28754.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like STE3 PF02076.15 EGO28756.1 - 3.7e-79 266.0 20.5 4.2e-79 265.8 20.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF3584 PF12128.8 EGO28757.1 - 0.0039 14.8 5.3 0.0052 14.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Cor1 PF04803.12 EGO28757.1 - 0.074 13.3 2.3 0.14 12.4 2.3 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Ribosomal_S30AE PF02482.19 EGO28757.1 - 0.085 13.6 1.4 0.23 12.3 1.3 1.8 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF668 PF05003.12 EGO28757.1 - 0.12 12.8 0.8 0.26 11.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Fib_alpha PF08702.10 EGO28757.1 - 0.54 10.4 3.0 0.91 9.7 3.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family STE3 PF02076.15 EGO28759.1 - 3.3e-92 308.8 22.3 3.7e-92 308.6 22.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 EGO28760.1 - 8.2e-113 376.4 30.2 9.5e-113 376.2 30.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 EGO28761.1 - 6.8e-112 373.4 19.1 8.2e-112 373.1 19.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 EGO28761.1 - 0.036 13.9 1.2 0.048 13.5 0.4 1.5 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Fascin PF06268.13 EGO28762.1 - 0.0051 17.0 0.0 0.0088 16.3 0.0 1.3 1 0 0 1 1 1 1 Fascin domain Agglutinin PF07468.11 EGO28762.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Agglutinin domain Fascin PF06268.13 EGO28763.1 - 0.001 19.3 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Fascin domain BNIP2 PF12496.8 EGO28765.1 - 0.15 12.4 4.4 0.12 12.8 3.0 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 HSCB_C PF07743.13 EGO28765.1 - 2.6 8.6 6.9 0.39 11.2 1.9 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain CNOT11 PF10155.9 EGO28769.1 - 1.9e-16 60.3 0.0 3.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pkinase PF00069.25 EGO28770.1 - 2.6e-72 243.4 1.9 4.2e-72 242.7 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28770.1 - 3.8e-52 177.1 0.6 1.2e-51 175.5 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EGO28770.1 - 7.7e-24 83.8 0.0 2.7e-23 82.1 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EGO28770.1 - 2e-07 31.4 1.6 3.3e-07 30.8 0.4 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EGO28770.1 - 2.9e-06 26.8 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO28770.1 - 1.9e-05 23.8 1.5 3.4e-05 23.0 1.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGO28770.1 - 4.3e-05 22.5 0.0 7.2e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO28770.1 - 0.0034 17.3 0.1 0.0083 16.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S19 PF00203.21 EGO28771.1 - 2.1e-26 91.6 0.0 2.7e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 HCV_NS4b PF01001.19 EGO28772.1 - 0.17 11.5 4.4 0.83 9.2 0.0 2.1 1 1 1 2 2 2 0 Hepatitis C virus non-structural protein NS4b Glyco_transf_20 PF00982.21 EGO28773.1 - 1.5e-140 469.1 0.0 1.9e-140 468.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGO28773.1 - 1.1e-19 70.5 0.0 2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF1087 PF06465.13 EGO28773.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) F-box-like PF12937.7 EGO28774.1 - 0.00019 21.3 0.4 0.00065 19.5 0.4 2.0 1 0 0 1 1 1 1 F-box-like Misat_Tub_SegII PF10644.9 EGO28775.1 - 6.5e-35 120.0 0.1 1.5e-34 118.8 0.1 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGO28775.1 - 3.6e-33 114.8 0.0 5.6e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 EGO28775.1 - 1.4e-05 25.4 0.1 0.0018 18.5 0.0 2.5 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain KAP_NTPase PF07693.14 EGO28777.1 - 0.024 13.9 0.5 0.095 11.9 0.3 1.8 1 1 1 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 EGO28777.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Barstar PF01337.18 EGO28777.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) BTB PF00651.31 EGO28779.1 - 4.8e-09 36.4 0.0 1.2e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain RNB PF00773.19 EGO28780.1 - 0.033 13.5 0.0 0.16 11.3 0.0 1.7 1 1 1 2 2 2 0 RNB domain PDCD2_C PF04194.13 EGO28781.1 - 4.3e-44 150.7 0.0 4.3e-44 150.7 0.0 2.4 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain WYL_2 PF10902.8 EGO28781.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold ApoO PF09769.9 EGO28782.1 - 8.9e-28 96.8 0.0 1.7e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein O VirB3 PF05101.13 EGO28783.1 - 0.038 14.2 2.4 0.038 14.2 2.4 2.7 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Lentivirus_VIF PF05851.11 EGO28785.1 - 0.047 12.6 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) SNF2_N PF00176.23 EGO28787.1 - 6.5e-56 189.5 0.0 1.1e-55 188.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO28787.1 - 3.7e-17 62.7 0.0 1.2e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 EGO28787.1 - 6.3e-05 22.8 19.0 0.00019 21.2 8.1 3.2 2 1 1 3 3 3 2 PHD-finger NOA36 PF06524.12 EGO28787.1 - 0.39 10.0 10.7 0.54 9.5 9.7 1.7 1 1 1 2 2 2 0 NOA36 protein C1_1 PF00130.22 EGO28787.1 - 3.6 7.6 22.8 0.36 10.7 3.6 3.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EGO28787.1 - 3.6 7.2 16.9 0.77 9.4 2.9 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EGO28787.1 - 4.3 7.0 9.3 1.7 8.3 5.8 2.2 1 1 1 2 2 2 0 PHD-finger DPM3 PF08285.11 EGO28788.1 - 5.5e-33 113.0 0.1 6.1e-33 112.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CSG2 PF16965.5 EGO28789.1 - 0.00044 19.3 1.1 0.00046 19.3 0.1 1.6 2 0 0 2 2 2 1 Ceramide synthase regulator EamA PF00892.20 EGO28789.1 - 0.02 15.0 7.0 0.02 15.0 7.0 4.1 3 1 0 4 4 4 0 EamA-like transporter family UPF0182 PF03699.13 EGO28789.1 - 0.089 10.9 4.7 0.14 10.2 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF2304 PF10066.9 EGO28789.1 - 3.2 8.0 10.6 0.24 11.6 1.4 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) adh_short PF00106.25 EGO28792.1 - 1.5e-43 148.5 0.0 2.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO28792.1 - 8.7e-28 97.5 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EGO28792.1 - 1.5e-06 28.2 0.1 2.3e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO28792.1 - 5.8e-06 26.3 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO28792.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGO28792.1 - 0.053 13.0 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EMC1_C PF07774.13 EGO28795.1 - 1.1e-76 257.2 0.2 3.8e-76 255.5 0.1 1.9 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EGO28795.1 - 5.7e-13 49.0 4.3 3e-07 30.3 0.8 3.8 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 EGO28795.1 - 2.5e-10 39.8 0.6 0.0029 17.5 0.0 4.5 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 EGO28795.1 - 0.011 16.2 2.5 0.13 12.8 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain Metallophos PF00149.28 EGO28796.1 - 2e-35 123.2 0.1 3.7e-35 122.3 0.1 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGO28796.1 - 0.00015 21.5 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain adh_short PF00106.25 EGO28797.1 - 2.5e-31 108.7 0.0 3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO28797.1 - 2.9e-15 56.5 0.0 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO28797.1 - 2.9e-07 30.6 0.3 5.5e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGO28797.1 - 0.058 12.5 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3435 PF11917.8 EGO28798.1 - 0.0013 17.8 0.2 0.0014 17.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-CCHC PF00098.23 EGO28799.1 - 5.8e-08 32.5 3.3 9.3e-08 31.8 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO28799.1 - 0.025 14.5 3.2 0.043 13.8 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO28799.1 - 0.11 12.2 1.0 0.19 11.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 EGO28799.1 - 0.23 11.0 1.3 0.43 10.1 1.3 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC PF00098.23 EGO28801.1 - 8.4e-08 31.9 1.2 1.2e-07 31.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO28801.1 - 0.0086 15.6 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCHC_6 PF15288.6 EGO28801.1 - 0.14 12.0 1.5 0.22 11.4 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle TLD PF07534.16 EGO28804.1 - 6.3e-06 26.4 0.0 6.8e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 TLD adh_short PF00106.25 EGO28806.1 - 1.6e-31 109.3 0.0 5.5e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO28806.1 - 8e-17 61.6 0.0 5.3e-13 49.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO28806.1 - 3.9e-12 46.4 0.0 5.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO28806.1 - 0.0016 17.9 0.0 0.0031 17.0 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO28806.1 - 0.0028 16.7 0.1 0.0072 15.4 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGO28806.1 - 0.0035 16.8 0.1 0.0059 16.0 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO28806.1 - 0.0038 17.2 0.0 0.066 13.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO28806.1 - 0.055 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGO28806.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain MMR_HSR1 PF01926.23 EGO28807.1 - 5.7e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO28807.1 - 0.00017 21.5 0.0 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 EGO28807.1 - 0.00017 21.6 0.1 0.64 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Septin PF00735.18 EGO28807.1 - 0.00069 19.0 0.1 0.25 10.6 0.0 2.3 1 1 0 2 2 2 2 Septin G-alpha PF00503.20 EGO28807.1 - 0.0012 18.0 0.3 0.058 12.5 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit AAA_16 PF13191.6 EGO28807.1 - 0.003 18.0 0.0 0.0084 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGO28807.1 - 0.0035 17.0 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGO28807.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGO28807.1 - 0.027 14.3 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EGO28807.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGO28807.1 - 0.042 13.0 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EGO28807.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Roc PF08477.13 EGO28807.1 - 0.057 13.6 0.1 0.26 11.5 0.0 2.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EGO28807.1 - 0.061 12.5 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SMC_N PF02463.19 EGO28807.1 - 0.069 12.6 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EGO28807.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 EGO28807.1 - 0.074 12.4 0.1 0.23 10.8 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 EGO28809.1 - 2e-05 24.1 0.1 0.0058 15.9 0.1 2.2 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGO28809.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EGO28809.1 - 0.0014 17.8 0.0 0.0025 17.1 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 EGO28809.1 - 0.0016 18.9 0.2 0.003 18.1 0.2 1.5 1 1 0 1 1 1 1 ABC transporter G-alpha PF00503.20 EGO28809.1 - 0.0017 17.6 1.1 0.087 12.0 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit Roc PF08477.13 EGO28809.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Myb_Cef PF11831.8 EGO28809.1 - 0.0034 17.0 0.4 0.0053 16.4 0.4 1.2 1 0 0 1 1 1 1 pre-mRNA splicing factor component PduV-EutP PF10662.9 EGO28809.1 - 0.0037 17.0 0.1 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EGO28809.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain Arf PF00025.21 EGO28809.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family ResIII PF04851.15 EGO28809.1 - 0.014 15.4 0.1 0.03 14.3 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EGO28809.1 - 0.014 15.7 0.3 0.07 13.5 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGO28809.1 - 0.015 15.2 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 EGO28809.1 - 0.015 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein TniB PF05621.11 EGO28809.1 - 0.024 14.0 0.1 0.13 11.7 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EGO28809.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EGO28809.1 - 0.033 14.6 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGO28809.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.22 EGO28809.1 - 0.043 13.4 0.0 0.097 12.3 0.0 1.6 1 1 0 1 1 1 0 Ras family NACHT PF05729.12 EGO28809.1 - 0.044 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 EGO28809.1 - 0.055 13.2 1.9 0.81 9.4 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EGO28809.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGO28809.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGO28809.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase Sigma54_activ_2 PF14532.6 EGO28809.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGO28809.1 - 0.11 12.2 0.2 0.16 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO28809.1 - 0.12 12.6 0.5 0.24 11.7 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGO28809.1 - 0.74 10.3 7.5 2.3 8.7 7.5 2.0 1 1 0 1 1 1 0 AAA domain DUF751 PF05421.11 EGO28810.1 - 1.6 9.5 8.7 0.14 12.9 2.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF751) DinB_2 PF12867.7 EGO28811.1 - 2e-07 31.6 0.3 2.5e-07 31.2 0.3 1.1 1 0 0 1 1 1 1 DinB superfamily Shikimate_DH PF01488.20 EGO28815.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 EGO28816.1 - 6.5e-39 133.9 0.0 7.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EGO28819.1 - 2.5e-39 135.2 36.2 2.5e-39 135.2 36.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO28819.1 - 4.2e-11 42.4 5.6 4.2e-11 42.4 5.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Gpr1_Fun34_YaaH PF01184.19 EGO28820.1 - 4.4e-59 199.6 19.8 5.5e-59 199.2 19.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mpv17_PMP22 PF04117.12 EGO28822.1 - 5.3e-21 74.6 0.3 8.9e-21 73.9 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 EGO28822.1 - 0.064 13.6 0.4 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FA_desaturase PF00487.24 EGO28822.1 - 0.69 9.7 4.5 2.2 8.1 2.4 1.9 1 1 1 2 2 2 0 Fatty acid desaturase RepL PF05732.11 EGO28826.1 - 0.11 12.0 0.3 0.77 9.2 0.0 1.9 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) p450 PF00067.22 EGO28827.1 - 2.7e-31 108.8 0.0 2.5e-24 85.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EGO28828.1 - 3.1e-39 135.0 0.0 4.3e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF5132 PF17195.4 EGO28828.1 - 0.082 13.0 0.5 0.82 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) YiiD_C PF09500.10 EGO28828.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) polyprenyl_synt PF00348.17 EGO28829.1 - 7.6e-52 175.9 0.0 9.2e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Adeno_PV PF03910.13 EGO28829.1 - 0.22 10.2 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV p450 PF00067.22 EGO28830.1 - 7.8e-73 245.8 0.0 1.1e-72 245.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO28831.1 - 2.1e-54 185.0 0.0 7.7e-54 183.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Prenyltrans PF00432.21 EGO28832.1 - 0.0063 16.2 0.4 2.6 7.9 0.0 3.4 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SyrA PF11089.8 EGO28832.1 - 0.092 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Exopolysaccharide production repressor Mago-bind PF09282.10 EGO28832.1 - 0.14 12.1 0.4 0.72 9.8 0.1 2.4 2 0 0 2 2 2 0 Mago binding Retrotran_gag_2 PF14223.6 EGO28833.1 - 4.2e-08 32.9 0.1 5.6e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Myb_DNA-bind_3 PF12776.7 EGO28834.1 - 2.9e-06 28.2 0.4 1.3e-05 26.0 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 EGO28834.1 - 0.012 16.3 0.8 0.05 14.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_4 PF13837.6 EGO28834.1 - 0.14 12.6 2.9 0.33 11.4 0.2 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain p450 PF00067.22 EGO28837.1 - 9e-60 202.7 0.0 1.7e-44 152.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EGO28838.1 - 1.2e-31 110.0 0.0 1.2e-30 106.7 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EGO28839.1 - 1.9e-14 53.6 0.5 3.5e-14 52.7 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO28839.1 - 2.2e-05 24.5 0.0 6.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like BAALC_N PF06989.12 EGO28839.1 - 0.012 15.9 0.2 0.038 14.3 0.0 1.9 1 1 1 2 2 2 0 BAALC N-terminus adh_short PF00106.25 EGO28840.1 - 9.9e-26 90.4 0.0 9.7e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO28840.1 - 8.1e-14 51.7 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO28840.1 - 1.8e-08 34.5 0.1 2.8e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO28840.1 - 8.6e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO28840.1 - 0.00029 20.4 0.0 0.00045 19.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EGO28840.1 - 0.026 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGO28840.1 - 0.072 13.0 0.6 0.1 12.4 0.6 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EGO28840.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGO28840.1 - 0.096 12.6 0.4 0.25 11.2 0.5 1.6 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_7 PF13241.6 EGO28840.1 - 0.23 11.9 0.6 0.41 11.1 0.2 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Transposase_21 PF02992.14 EGO28841.1 - 0.00061 19.1 0.0 0.0011 18.2 0.0 1.4 1 1 1 2 2 2 1 Transposase family tnp2 CC2-LZ PF16516.5 EGO28842.1 - 0.0078 16.6 7.3 0.0078 16.6 7.3 1.6 2 0 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PDDEXK_6 PF04720.12 EGO28842.1 - 0.013 15.5 3.0 0.03 14.3 3.0 1.6 1 0 0 1 1 1 0 PDDEXK-like family of unknown function HAUS-augmin3 PF14932.6 EGO28842.1 - 0.019 14.6 8.9 0.044 13.4 8.9 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4763 PF15960.5 EGO28842.1 - 0.045 13.1 8.0 0.62 9.3 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) FAM76 PF16046.5 EGO28842.1 - 0.39 10.0 7.0 0.62 9.4 7.0 1.2 1 0 0 1 1 1 0 FAM76 protein HTH_57 PF18679.1 EGO28842.1 - 1.9 8.9 6.2 1.7 9.0 1.2 2.4 1 1 1 2 2 2 0 ThcOx helix turn helix domain KELK PF15796.5 EGO28842.1 - 4.2 7.9 7.5 1.6 9.2 2.1 2.3 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 EGO28842.1 - 4.5 7.3 8.9 1.3 9.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Dfp1_Him1_M PF08630.10 EGO28842.1 - 5.3 7.3 8.5 9.4 6.5 0.2 2.4 2 0 0 2 2 2 0 Dfp1/Him1, central region gag-asp_proteas PF13975.6 EGO28843.1 - 2.5e-05 24.7 0.0 3.6e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28843.1 - 0.00019 22.0 0.0 0.00027 21.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO28843.1 - 0.0065 16.3 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 EGO28844.1 - 1.2e-05 25.2 3.3 2.4e-05 24.2 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO28844.1 - 1.7e-05 24.7 5.1 1.7e-05 24.7 5.1 1.7 2 0 0 2 2 2 1 Zinc knuckle RPA43_OB PF17875.1 EGO28844.1 - 0.084 13.5 0.7 0.11 13.1 0.7 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I zf-C2H2 PF00096.26 EGO28845.1 - 0.00087 19.6 12.4 0.094 13.2 1.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EGO28845.1 - 0.0019 17.9 6.1 0.023 14.4 1.6 2.8 2 0 0 2 2 2 1 zinc-finger C2H2-type FAM117 PF15388.6 EGO28845.1 - 0.0035 16.8 5.5 0.0041 16.6 5.5 1.1 1 0 0 1 1 1 1 Protein Family FAM117 zf-C2H2_4 PF13894.6 EGO28845.1 - 0.011 16.5 10.6 1.5 9.9 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger ADK_lid PF05191.14 EGO28845.1 - 0.04 13.9 3.7 0.89 9.6 0.3 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-MYST PF17772.1 EGO28845.1 - 0.043 13.4 0.7 1 9.0 1.0 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain RsfS PF02410.15 EGO28845.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation zf-UBP PF02148.19 EGO28845.1 - 1.7 9.0 7.0 29 5.1 6.6 2.2 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Piezo_RRas_bdg PF12166.8 EGO28848.1 - 0.0002 20.8 0.0 0.00022 20.7 0.0 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain RPS31 PF17067.5 EGO28849.1 - 0.14 12.3 6.2 4.2 7.6 0.0 4.1 2 1 3 5 5 5 0 Ribosomal protein S31e TTc_toxin_rep PF18807.1 EGO28849.1 - 3.5 7.5 15.6 17 5.3 0.0 6.8 7 1 0 8 8 8 0 Tripartite Tc toxins repeat NACHT PF05729.12 EGO28850.1 - 0.00014 21.8 0.0 0.00095 19.1 0.0 2.4 2 1 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.14 EGO28850.1 - 0.16 11.2 1.2 0.89 8.7 0.9 1.9 1 1 1 2 2 2 0 KAP family P-loop domain gag-asp_proteas PF13975.6 EGO28852.1 - 2.8e-05 24.6 0.0 5.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO28852.1 - 3.1e-05 24.5 0.0 4.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO28852.1 - 0.0029 17.4 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 EGO28853.1 - 3.9e-07 29.8 4.9 8.5e-07 28.8 4.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO28853.1 - 0.0012 19.1 0.2 0.0037 17.5 0.2 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein MerR-DNA-bind PF09278.11 EGO28853.1 - 0.18 12.4 3.6 5.7 7.6 0.0 3.3 3 0 0 3 3 3 0 MerR, DNA binding DUF2937 PF11157.8 EGO28854.1 - 0.1 12.3 0.1 0.33 10.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) KDZ PF18758.1 EGO28855.1 - 4.6e-36 124.5 0.1 5.2e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Cauli_VI PF01693.16 EGO28856.1 - 0.068 13.5 5.3 0.1 12.9 5.3 1.3 1 0 0 1 1 1 0 Caulimovirus viroplasmin Presenilin PF01080.17 EGO28857.1 - 6 5.5 4.5 7.5 5.2 4.5 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 EGO28858.1 - 0.033 13.4 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Chorion_2 PF03964.15 EGO28859.1 - 0.047 14.5 1.4 0.077 13.8 0.5 1.7 2 0 0 2 2 2 0 Chorion family 2 Pesticin PF16754.5 EGO28859.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term ABC_tran PF00005.27 EGO28860.1 - 7.5e-50 169.0 0.0 7.8e-30 104.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO28860.1 - 4e-45 154.6 31.0 3.1e-26 92.6 5.0 3.5 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EGO28860.1 - 3.6e-08 33.1 0.3 0.0079 15.7 1.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EGO28860.1 - 4.2e-07 29.3 0.1 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 EGO28860.1 - 2.1e-06 27.8 3.2 0.17 11.6 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO28860.1 - 1.5e-05 25.6 0.1 0.018 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGO28860.1 - 4.9e-05 23.0 0.8 0.29 10.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO28860.1 - 6e-05 23.5 0.1 0.62 10.4 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EGO28860.1 - 0.00048 19.8 0.2 0.27 10.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EGO28860.1 - 0.00067 19.8 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 EGO28860.1 - 0.0011 19.3 0.3 9.7 6.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.22 EGO28860.1 - 0.0088 15.2 0.7 0.46 9.6 0.2 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 EGO28860.1 - 0.012 15.1 0.1 4.5 6.7 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EGO28860.1 - 0.018 15.1 0.4 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGO28860.1 - 0.064 13.3 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family PhoH PF02562.16 EGO28860.1 - 0.067 12.6 0.3 14 5.0 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein AAA_15 PF13175.6 EGO28860.1 - 0.083 12.6 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EGO28860.1 - 0.087 12.7 0.2 4.2 7.2 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EGO28860.1 - 0.098 11.9 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 EGO28860.1 - 0.1 12.5 0.2 21 5.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 EGO28860.1 - 0.15 12.1 0.1 5.8 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EGO28860.1 - 0.16 11.3 0.6 6.6 6.0 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 EGO28860.1 - 0.17 11.8 0.7 4 7.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EGO28860.1 - 0.19 11.3 0.4 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CcmD PF04995.14 EGO28860.1 - 1.6 8.9 5.9 0.28 11.3 0.1 3.1 2 0 0 2 2 1 0 Heme exporter protein D (CcmD) F_bP_aldolase PF01116.20 EGO28862.1 - 3.3e-72 243.3 0.0 3.7e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II 7TM_GPCR_Srh PF10318.9 EGO28864.1 - 0.0093 15.0 0.2 0.0093 15.0 0.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh MARVEL PF01284.23 EGO28865.1 - 1.4e-05 25.1 11.4 1.5e-05 25.0 10.4 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF2583 PF10762.9 EGO28865.1 - 0.18 12.2 1.8 0.39 11.2 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2583) Tetraspanin PF00335.20 EGO28865.1 - 0.69 9.6 8.8 5.7 6.6 0.0 2.4 2 1 0 2 2 2 0 Tetraspanin family TctB PF07331.11 EGO28865.1 - 0.95 9.7 15.2 2.4 8.4 14.2 1.9 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4079 PF13301.6 EGO28865.1 - 2.5 8.2 11.0 4.3 7.5 7.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) RAI1 PF08652.11 EGO28866.1 - 3.5e-10 39.9 0.0 5.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Plavaka PF18759.1 EGO28867.1 - 8.5e-18 64.6 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Pkinase_fungal PF17667.1 EGO28868.1 - 3.8e-21 75.3 0.0 5.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO28868.1 - 8e-10 38.5 0.1 1.6e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28868.1 - 0.00022 20.6 0.6 0.00053 19.4 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 EGO28868.1 - 0.008 15.5 0.2 0.023 14.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGO28869.1 - 2.4e-27 95.8 0.1 2.8e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Myb_DNA-bind_3 PF12776.7 EGO28870.1 - 1.1e-08 35.9 0.1 1.6e-08 35.5 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO28870.1 - 0.00071 19.9 0.1 0.001 19.4 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Methyltransf_22 PF13383.6 EGO28872.1 - 9.8e-22 77.7 0.0 1.2e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EGO28872.1 - 8.3e-08 32.4 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Dicty_REP PF05086.12 EGO28873.1 - 3.1 5.6 6.3 3.5 5.5 6.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2012 PF09430.10 EGO28875.1 - 4e-21 75.4 0.1 8e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 EGO28875.1 - 0.0089 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 EGO28875.1 - 0.031 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II SH2 PF00017.24 EGO28875.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 SH2 domain Pkinase_fungal PF17667.1 EGO28877.1 - 0.0017 17.2 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF1771 PF08590.10 EGO28878.1 - 0.045 14.1 1.1 0.067 13.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) zf-CCHC_4 PF14392.6 EGO28878.1 - 0.054 13.2 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO28878.1 - 0.084 12.6 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger F-box-like PF12937.7 EGO28882.1 - 3.4e-06 26.8 0.1 3.4e-06 26.8 0.1 4.3 4 1 1 5 5 5 2 F-box-like F-box-like PF12937.7 EGO28883.1 - 8.8e-09 35.1 1.3 2.4e-08 33.7 1.3 1.8 1 0 0 1 1 1 1 F-box-like DUF3808 PF10300.9 EGO28885.1 - 4.8e-70 236.6 0.1 7.1e-70 236.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 EGO28885.1 - 0.00047 20.7 0.1 0.22 12.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO28885.1 - 0.0014 18.6 7.0 2.5 8.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGO28885.1 - 0.011 16.3 1.4 0.29 11.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO28885.1 - 0.016 16.0 0.3 1.3 10.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO28885.1 - 0.14 12.4 4.1 26 5.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO28885.1 - 0.27 11.1 4.0 14 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.18 EGO28886.1 - 3e-10 40.0 18.5 5.5e-10 39.2 18.5 1.5 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 EGO28886.1 - 1.6e-06 28.5 0.0 0.065 13.8 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO28886.1 - 8.9e-06 25.7 0.0 0.007 16.8 0.0 3.8 4 0 0 4 4 3 1 Ankyrin repeat Ank_2 PF12796.7 EGO28886.1 - 2e-05 25.1 0.0 6.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO28886.1 - 0.00016 22.0 0.8 0.0046 17.3 0.0 3.3 4 0 0 4 4 3 1 Ankyrin repeat Ank_5 PF13857.6 EGO28886.1 - 0.00032 20.9 0.0 0.0028 17.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ecl1 PF12855.7 EGO28886.1 - 0.0083 17.3 4.5 0.016 16.4 4.5 1.4 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2256 PF10013.9 EGO28886.1 - 0.048 13.8 6.2 0.099 12.8 6.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Phage_int_SAM_6 PF18644.1 EGO28886.1 - 0.19 11.7 0.2 0.32 11.0 0.2 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain zf-HIT PF04438.16 EGO28886.1 - 0.44 10.5 8.6 0.8 9.6 8.6 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 EGO28886.1 - 0.68 10.3 13.0 1.2 9.5 13.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gti1_Pac2 PF09729.9 EGO28889.1 - 4.7e-30 105.0 0.2 5.4e-27 95.0 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family F-box-like PF12937.7 EGO28892.1 - 1.4e-08 34.5 1.0 4.7e-08 32.8 1.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.13 EGO28892.1 - 0.025 15.2 0.1 0.17 12.6 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat F-box PF00646.33 EGO28892.1 - 4.9 7.1 7.7 5.3 7.0 0.3 3.6 3 0 0 3 3 3 0 F-box domain KDZ PF18758.1 EGO28897.1 - 0.0035 17.0 0.1 0.0055 16.3 0.2 1.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Retrotran_gag_2 PF14223.6 EGO28899.1 - 1.4e-13 50.7 0.1 1.8e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO28899.1 - 8.3e-05 22.2 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO28899.1 - 0.002 17.9 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Cas_Csy1 PF09611.10 EGO28899.1 - 0.055 12.5 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) DUF3527 PF12043.8 EGO28900.1 - 0.0015 18.2 0.2 0.0017 18.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) MLVIN_C PF18697.1 EGO28901.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain PXA PF02194.15 EGO28902.1 - 4.6e-42 144.0 1.5 1e-41 142.9 1.5 1.6 1 0 0 1 1 1 1 PXA domain GDPD_2 PF13653.6 EGO28902.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family SPOC PF07744.13 EGO28903.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 SPOC domain Chromo PF00385.24 EGO28904.1 - 1.4e-12 47.3 0.4 2.8e-12 46.3 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EGO28904.1 - 0.011 15.6 0.5 0.011 15.6 0.5 1.8 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Myb_DNA-bind_3 PF12776.7 EGO28907.1 - 8.8e-07 29.8 0.4 2e-06 28.7 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NPCBM PF08305.11 EGO28907.1 - 0.031 14.5 0.1 0.069 13.3 0.1 1.5 1 0 0 1 1 1 0 NPCBM/NEW2 domain Myb_DNA-bind_4 PF13837.6 EGO28907.1 - 0.044 14.2 0.2 0.091 13.2 0.2 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nuc_rec_co-act PF08815.10 EGO28907.1 - 0.091 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator AP3D1 PF06375.11 EGO28911.1 - 0.055 13.7 7.0 0.066 13.4 7.0 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ABC_tran PF00005.27 EGO28912.1 - 2e-50 170.8 0.0 1.5e-29 103.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO28912.1 - 1.2e-44 153.0 21.5 3.7e-25 89.1 4.3 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EGO28912.1 - 5.9e-08 32.4 1.4 0.0026 17.2 1.4 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGO28912.1 - 2.2e-07 31.0 3.2 0.084 12.7 0.1 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGO28912.1 - 7.7e-07 28.4 0.2 0.0023 17.0 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EGO28912.1 - 5.4e-06 26.1 0.1 0.21 11.4 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO28912.1 - 7.4e-06 26.6 0.1 0.0018 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGO28912.1 - 2.9e-05 23.7 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO28912.1 - 0.00077 19.9 1.5 0.76 10.1 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 EGO28912.1 - 0.01 16.0 0.2 0.028 14.5 0.1 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_22 PF13401.6 EGO28912.1 - 0.01 16.1 0.8 14 5.9 0.1 3.5 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 EGO28912.1 - 0.032 14.1 0.2 0.26 11.2 0.0 2.5 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EGO28912.1 - 0.059 13.5 1.0 2.9 8.0 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGO28912.1 - 0.07 12.9 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EGO28912.1 - 0.087 12.3 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 EGO28912.1 - 0.095 12.6 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EGO28912.1 - 0.1 11.7 0.1 0.75 8.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RseC_MucC PF04246.12 EGO28912.1 - 0.11 12.5 1.5 0.51 10.3 0.2 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC cobW PF02492.19 EGO28912.1 - 0.13 11.9 1.1 0.87 9.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EGO28912.1 - 0.14 12.2 0.3 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 EGO28912.1 - 0.14 11.6 0.1 13 5.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGO28912.1 - 0.17 12.0 0.1 31 4.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGO28912.1 - 0.2 11.3 0.0 5.7 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EGO28912.1 - 0.51 10.3 1.8 4.5 7.3 0.1 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGO28912.1 - 0.52 10.2 1.9 6.7 6.6 0.1 2.7 2 0 0 2 2 2 0 NACHT domain 4HBT_2 PF13279.6 EGO28919.1 - 2.2e-09 37.8 0.0 4.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase_Tyr PF07714.17 EGO28920.1 - 8.8e-37 126.8 0.0 6.6e-24 84.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGO28920.1 - 1.2e-26 93.7 0.0 1.1e-14 54.5 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 EGO28920.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FinO_N PF12602.8 EGO28920.1 - 0.025 14.9 0.0 0.072 13.4 0.0 1.8 1 0 0 1 1 1 0 Fertility inhibition protein N terminal APH PF01636.23 EGO28920.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Plavaka PF18759.1 EGO28922.1 - 7.1e-14 51.8 0.1 9.5e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Glyco_hydro_3_C PF01915.22 EGO28923.1 - 1.1e-50 172.5 0.0 2e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO28923.1 - 5.5e-35 121.3 0.1 9.6e-35 120.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO28923.1 - 4e-19 68.5 0.0 9e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Alpha_GJ PF03229.13 EGO28923.1 - 2.5 8.7 10.7 6.6 7.3 10.7 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Glyco_hydro_3_C PF01915.22 EGO28924.1 - 2e-49 168.4 0.0 3.5e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO28924.1 - 2.2e-37 129.1 0.0 3.7e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO28924.1 - 1.4e-16 60.3 0.0 2.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Alpha_GJ PF03229.13 EGO28924.1 - 1.9 9.1 13.2 5.2 7.6 13.2 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Pheromone PF08015.11 EGO28925.1 - 0.0094 17.0 1.0 0.18 12.9 1.0 2.0 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EGO28926.1 - 0.0037 18.3 2.8 0.11 13.5 2.8 2.1 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EGO28927.1 - 4.2e-07 30.9 1.6 6.4e-07 30.3 1.6 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EGO28928.1 - 7.7e-05 23.7 0.7 0.00035 21.6 0.7 1.8 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EGO28929.1 - 0.021 15.9 1.5 0.14 13.2 1.5 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone ResIII PF04851.15 EGO28930.1 - 5.8e-22 78.5 0.0 1e-21 77.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO28930.1 - 3.1e-15 56.5 0.1 9.8e-15 54.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO28930.1 - 8.9e-15 54.9 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGO28930.1 - 4.7e-05 23.2 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGO28930.1 - 0.0034 17.6 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EGO28930.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 EGO28930.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGO28930.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 EGO28930.1 - 0.059 12.1 0.0 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain DEAD_2 PF06733.15 EGO28930.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Retrotran_gag_2 PF14223.6 EGO28931.1 - 9.9e-14 51.2 0.1 1.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.8 EGO28935.1 - 1.2e-44 151.7 1.1 1.7e-44 151.2 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGO28935.1 - 3.4e-18 65.2 0.0 7.6e-18 64.1 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGO28935.1 - 0.0099 16.1 1.1 10 6.3 0.1 3.1 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter OAM_alpha PF16552.5 EGO28935.1 - 0.015 15.1 0.0 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 D-ornithine 4,5-aminomutase alpha-subunit RRM_3 PF08777.11 EGO28935.1 - 0.044 13.8 0.3 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif F-box-like PF12937.7 EGO28937.1 - 0.053 13.4 0.3 0.41 10.6 0.3 2.4 1 1 0 1 1 1 0 F-box-like AdoMet_MTase PF07757.13 EGO28938.1 - 7.2e-33 113.3 0.0 2.3e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 EGO28938.1 - 0.065 13.0 0.1 0.33 10.8 0.3 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGO28938.1 - 0.11 13.2 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGO28938.1 - 0.26 11.2 0.7 0.84 9.6 0.7 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCI PF01399.27 EGO28939.1 - 4.8e-05 23.8 0.0 0.00014 22.3 0.0 1.8 2 0 0 2 2 2 1 PCI domain FMO-like PF00743.19 EGO28940.1 - 2.9e-25 88.7 0.0 3.5e-15 55.4 0.0 3.3 4 0 0 4 4 4 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO28940.1 - 5.6e-10 39.0 0.0 7.1e-08 32.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase STE3 PF02076.15 EGO28940.1 - 3.1e-08 33.2 0.2 5e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 Pheromone A receptor Pyr_redox_2 PF07992.14 EGO28940.1 - 1.8e-07 30.7 0.0 8.7e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO28940.1 - 7.2e-07 28.7 0.0 0.0001 21.6 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO28940.1 - 1.2e-06 28.6 0.0 8.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO28940.1 - 0.0023 18.0 0.0 0.023 14.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EGO28940.1 - 0.0088 15.3 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGO28940.1 - 0.018 14.3 0.0 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EGO28940.1 - 0.059 12.1 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 EGO28940.1 - 0.064 12.5 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DAO PF01266.24 EGO28940.1 - 0.14 11.7 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Wzy_C PF04932.15 EGO28940.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 O-Antigen ligase Pyr_redox PF00070.27 EGO28940.1 - 0.24 12.0 0.0 10 6.8 0.0 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 EGO28941.1 - 1.8e-63 214.9 0.0 7.8e-63 212.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 EGO28942.1 - 8.5e-25 87.2 0.0 9.1e-15 54.1 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO28942.1 - 3.2e-09 36.5 0.0 1.1e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO28942.1 - 1e-07 31.5 0.0 3.5e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO28942.1 - 9.4e-07 28.3 0.0 0.0001 21.6 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO28942.1 - 1.1e-05 25.6 0.0 3.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO28942.1 - 0.019 14.2 0.0 0.067 12.4 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EGO28942.1 - 0.026 14.5 0.1 0.34 10.9 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding PGI PF00342.19 EGO28943.1 - 1.3e-194 647.4 3.3 9.3e-153 509.3 0.3 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase Bombolitin PF08096.11 EGO28943.1 - 9.1 6.8 6.6 92 3.6 0.3 3.4 2 1 1 3 3 3 0 Bombolitin family DUF3602 PF12223.8 EGO28947.1 - 4.3e-19 68.9 35.3 5.2e-07 30.2 4.5 5.4 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) YabA PF06156.13 EGO28952.1 - 0.02 15.5 1.4 0.045 14.4 1.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA TMCO5 PF14992.6 EGO28952.1 - 0.027 14.0 2.3 0.046 13.3 2.3 1.3 1 0 0 1 1 1 0 TMCO5 family DUF848 PF05852.11 EGO28952.1 - 0.035 14.2 1.7 0.072 13.2 1.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Cnn_1N PF07989.11 EGO28952.1 - 0.036 14.2 4.3 0.076 13.2 4.3 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HAUS6_N PF14661.6 EGO28952.1 - 0.042 13.4 1.1 0.068 12.7 1.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Attacin_N PF03768.15 EGO28952.1 - 0.074 13.2 0.1 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Attacin, N-terminal region DivIC PF04977.15 EGO28952.1 - 0.13 12.0 3.4 0.31 10.8 3.4 1.6 1 0 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 EGO28952.1 - 0.14 12.6 3.4 0.078 13.4 0.9 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 EGO28952.1 - 0.31 11.1 2.9 0.63 10.2 2.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 EGO28952.1 - 0.35 11.3 5.6 0.19 12.2 2.8 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF724 PF05266.14 EGO28952.1 - 0.43 10.4 4.9 0.75 9.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 EGO28952.1 - 0.84 9.8 3.4 1.5 9.0 2.7 1.8 1 1 0 1 1 1 0 bZIP transcription factor Pkinase_fungal PF17667.1 EGO28955.1 - 6e-46 157.0 0.0 3.7e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase MFS_1 PF07690.16 EGO28955.1 - 6e-17 61.6 38.8 7.1e-11 41.6 16.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.25 EGO28955.1 - 8.1e-08 31.9 0.1 1.7e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO28955.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase YhdB PF14148.6 EGO28955.1 - 0.016 15.3 0.5 0.19 11.8 0.1 2.4 2 0 0 2 2 2 0 YhdB-like protein APH PF01636.23 EGO28955.1 - 0.23 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.25 EGO28956.1 - 4.6e-30 104.5 0.0 1.6e-29 102.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO28956.1 - 8.2e-12 45.2 0.0 2.5e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO28956.1 - 9.6e-07 28.9 0.0 1.9e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 KR domain SP24 PF16504.5 EGO28956.1 - 0.0013 18.7 0.1 0.0024 17.9 0.1 1.4 1 0 0 1 1 1 1 Putative virion membrane protein of plant and insect virus Polysacc_synt_2 PF02719.15 EGO28956.1 - 0.0086 15.2 0.0 0.076 12.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EGO28956.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EGO28957.1 - 5.5e-31 107.6 0.0 7.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO28957.1 - 2.7e-13 50.0 0.0 3.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO28957.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO28957.1 - 0.023 14.1 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EGO28957.1 - 0.028 13.5 0.0 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FHA PF00498.26 EGO28959.1 - 4.5e-17 62.2 0.1 1e-16 61.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO28959.1 - 0.00051 20.3 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5633 PF18656.1 EGO28959.1 - 0.21 11.5 0.4 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Cys_Met_Meta_PP PF01053.20 EGO28960.1 - 5.3e-126 420.2 0.0 1.3e-96 323.4 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGO28960.1 - 0.00029 20.1 0.0 0.0004 19.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EGO28960.1 - 0.0011 17.5 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase PAPA-1 PF04795.12 EGO28962.1 - 2.7e-21 76.2 2.4 2.7e-21 76.2 2.4 1.9 2 0 0 2 2 2 1 PAPA-1-like conserved region Rotamase_2 PF13145.6 EGO28962.1 - 0.1 13.4 1.2 0.15 12.9 1.2 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Peptidase_S49_N PF08496.10 EGO28962.1 - 0.52 10.4 4.1 0.72 9.9 4.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ferritin_2 PF13668.6 EGO28963.1 - 1.6e-40 138.5 1.1 1.6e-40 138.5 1.1 1.8 2 0 0 2 2 2 1 Ferritin-like domain Ferritin_2 PF13668.6 EGO28964.1 - 2.1e-43 147.8 0.8 3.7e-43 147.0 0.8 1.4 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 EGO28965.1 - 7.4e-15 55.3 0.1 1.2e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain HpcH_HpaI PF03328.14 EGO28966.1 - 1.6e-31 109.2 0.0 1.9e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3431 PF11913.8 EGO28968.1 - 0.001 18.9 0.1 0.0017 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1294 PF06961.13 EGO28969.1 - 0.21 11.8 0.4 65 3.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) Wzy_C_2 PF11846.8 EGO28970.1 - 1.1 9.2 3.1 2 8.3 0.3 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal LMF1 PF06762.14 EGO28970.1 - 2.9 6.9 7.9 4.7 6.2 7.9 1.5 1 1 0 1 1 1 0 Lipase maturation factor DUF872 PF05915.12 EGO28970.1 - 6.3 7.0 6.1 16 5.7 0.2 3.0 1 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) p450 PF00067.22 EGO28971.1 - 5.1e-64 216.7 0.0 1.2e-63 215.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ammonium_transp PF00909.21 EGO28974.1 - 1e-119 399.8 20.5 1.2e-119 399.6 20.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_43 PF04616.14 EGO28975.1 - 4.5e-37 127.9 0.1 5.3e-37 127.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Filamin PF00630.19 EGO28975.1 - 0.099 13.5 0.0 0.23 12.3 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat Gln-synt_C PF00120.24 EGO28976.1 - 2.8e-69 233.7 0.0 3.6e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Vps4_C PF09336.10 EGO28976.1 - 0.092 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Indigoidine_A PF04227.12 EGO28980.1 - 5.7e-127 423.0 0.5 1.2e-126 422.0 0.2 1.8 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 EGO28980.1 - 2.1e-17 63.4 0.0 2e-07 30.7 0.0 2.7 2 1 1 3 3 3 2 pfkB family carbohydrate kinase Mannosyl_trans3 PF11051.8 EGO28980.1 - 0.037 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative CSD2 PF17876.1 EGO28983.1 - 0.043 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Cold shock domain Myb_DNA-bind_3 PF12776.7 EGO28985.1 - 0.014 16.3 0.1 0.023 15.7 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RskA PF10099.9 EGO28985.1 - 0.027 14.8 0.4 0.036 14.3 0.4 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF659 PF04937.15 EGO28986.1 - 1.1e-05 25.3 0.0 3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Plavaka PF18759.1 EGO28988.1 - 8e-20 71.3 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF2162 PF09930.9 EGO28988.1 - 0.3 10.5 1.1 0.53 9.7 1.1 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) AAA_9 PF12781.7 EGO28990.1 - 0.16 11.0 0.3 0.18 10.9 0.3 1.0 1 0 0 1 1 1 0 ATP-binding dynein motor region TTL PF03133.15 EGO28992.1 - 5.4e-46 157.0 0.0 6.9e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MLVIN_C PF18697.1 EGO28997.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF5137 PF17220.3 EGO28998.1 - 0.1 13.5 0.1 0.11 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) AAA_9 PF12781.7 EGO28998.1 - 0.14 11.3 0.2 0.16 11.1 0.2 1.0 1 0 0 1 1 1 0 ATP-binding dynein motor region Apc13p PF05839.11 EGO29001.1 - 0.056 13.6 1.7 0.056 13.6 1.7 1.8 1 1 1 2 2 2 0 Apc13p protein Plavaka PF18759.1 EGO29002.1 - 5.3e-12 45.6 0.9 9.8e-12 44.7 0.9 1.5 1 1 0 1 1 1 1 Plavaka transposase ZapB PF06005.12 EGO29003.1 - 0.067 13.6 0.3 0.1 13.0 0.3 1.2 1 0 0 1 1 1 0 Cell division protein ZapB RTC4 PF14474.6 EGO29005.1 - 1.2e-11 44.9 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain IspD PF01128.19 EGO29006.1 - 0.052 13.3 0.0 0.055 13.2 0.0 1.0 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase sCache_3_2 PF17203.4 EGO29014.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Single cache domain 3 Meth_synt_2 PF01717.18 EGO29016.1 - 3.5e-18 66.0 0.0 2.5e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGO29016.1 - 0.0092 15.5 0.0 0.7 9.3 0.0 2.9 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Aldose_epim PF01263.20 EGO29024.1 - 6.7e-28 97.9 0.1 7.7e-28 97.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1275 PF06912.11 EGO29027.1 - 9.9e-32 110.4 16.5 1.3e-31 110.1 16.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2264 PF10022.9 EGO29031.1 - 4.6e-143 476.6 0.1 5.6e-143 476.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) p450 PF00067.22 EGO29033.1 - 0.0026 16.6 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EGO29034.1 - 2.5e-29 102.1 0.3 2.9e-28 98.7 0.3 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGO29034.1 - 1.4e-20 73.6 0.0 2.1e-19 69.7 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EGO29034.1 - 7.2e-11 42.0 0.0 9.2e-10 38.4 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO29034.1 - 3.2e-05 23.5 0.0 0.00041 19.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO29034.1 - 0.00079 18.5 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EGO29034.1 - 0.034 14.5 0.0 0.097 13.0 0.0 1.9 1 1 0 1 1 1 0 Phosphopantetheine attachment site zf-CCHC PF00098.23 EGO29036.1 - 4e-06 26.6 5.1 5.7e-06 26.2 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO29036.1 - 4.3e-06 26.6 3.3 6.9e-06 25.9 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EGO29036.1 - 0.062 13.0 2.4 0.11 12.2 2.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4939 PF16297.5 EGO29037.1 - 0.015 15.2 0.8 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EGO29038.1 - 0.0096 16.0 0.6 0.016 15.2 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EGO29039.1 - 1.7e-06 27.9 0.0 1.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO29039.1 - 1.9e-06 28.3 0.0 2.2e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO29039.1 - 2e-05 25.1 0.0 2.4e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease DUF5317 PF17248.2 EGO29041.1 - 0.066 13.2 0.6 0.089 12.8 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5317) zf-CCHC_3 PF13917.6 EGO29042.1 - 0.042 13.8 3.7 0.074 13.0 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DZR PF12773.7 EGO29042.1 - 0.16 12.0 4.7 0.28 11.2 4.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGO29042.1 - 0.99 9.2 7.4 0.4 10.5 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CxC2 PF18803.1 EGO29044.1 - 1.3e-21 76.7 0.4 2.8e-21 75.7 0.1 1.7 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGO29044.1 - 2.5e-17 63.3 0.1 1.2e-15 57.7 0.0 2.1 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGO29044.1 - 2.4e-07 30.8 0.1 4.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Thyroglob_assoc PF16597.5 EGO29047.1 - 0.069 13.5 0.2 0.23 11.8 0.2 1.8 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain Indigoidine_A PF04227.12 EGO29048.1 - 3.3e-116 387.7 0.5 7.3e-116 386.6 0.5 1.6 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EGO29048.1 - 1e-16 61.1 0.0 2.1e-07 30.6 0.0 2.7 2 1 1 3 3 3 2 pfkB family carbohydrate kinase Mannosyl_trans3 PF11051.8 EGO29048.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative DUF2510 PF10708.9 EGO29049.1 - 0.38 10.6 3.0 0.86 9.4 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) NRBF2 PF08961.10 EGO29050.1 - 0.024 14.3 0.2 0.05 13.2 0.2 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Csm1_N PF18504.1 EGO29050.1 - 0.026 14.9 0.5 0.077 13.4 0.5 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain bZIP_1 PF00170.21 EGO29050.1 - 0.065 13.3 1.8 0.13 12.4 1.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor Cnn_1N PF07989.11 EGO29050.1 - 0.15 12.3 3.0 0.59 10.3 3.0 2.0 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EGO29050.1 - 0.33 10.8 2.5 0.88 9.4 2.5 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF659 PF04937.15 EGO29054.1 - 9.5e-06 25.5 0.0 2.3e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Myb_DNA-bind_3 PF12776.7 EGO29056.1 - 0.0014 19.6 0.1 0.0025 18.8 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Di19_C PF14571.6 EGO29056.1 - 3.8 8.1 7.0 2.2 8.9 0.1 2.6 2 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal Retrotrans_gag PF03732.17 EGO29060.1 - 6.3e-06 26.4 0.1 6.3e-06 26.4 0.1 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Thyroglob_assoc PF16597.5 EGO29062.1 - 0.027 14.8 0.2 0.057 13.7 0.2 1.5 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain Plavaka PF18759.1 EGO29065.1 - 3.6e-16 59.3 0.0 3.9e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase zf-CCHC_3 PF13917.6 EGO29066.1 - 0.14 12.1 3.8 0.37 10.8 3.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Citrate_bind PF16114.5 EGO29072.1 - 1.9e-88 294.6 0.0 4.9e-88 293.3 0.0 1.7 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EGO29072.1 - 1.2e-19 70.6 0.0 5.8e-17 61.8 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGO29072.1 - 7.1e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EGO29072.1 - 3.1e-14 53.4 0.0 6.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EGO29072.1 - 4e-07 29.8 0.0 7.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EGO29072.1 - 4.4e-05 23.3 0.0 0.00012 21.8 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain STE3 PF02076.15 EGO29073.1 - 1.9e-95 319.4 20.5 2.2e-95 319.2 20.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 EGO29073.1 - 0.0057 16.0 6.9 0.011 15.1 6.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3094 PF11293.8 EGO29073.1 - 0.33 10.7 2.1 15 5.4 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DUF3810 PF12725.7 EGO29073.1 - 2.6 7.3 7.8 8.2 5.7 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) YuiB PF14068.6 EGO29073.1 - 7.2 7.3 9.4 0.16 12.6 0.7 2.7 3 0 0 3 3 3 0 Putative membrane protein BTB PF00651.31 EGO29074.1 - 5.9e-07 29.7 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rad60-SLD_2 PF13881.6 EGO29076.1 - 2.4e-14 53.4 0.0 2.9e-13 49.9 0.0 2.0 1 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGO29076.1 - 0.0001 22.0 0.0 0.00038 20.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family DnaJ PF00226.31 EGO29081.1 - 9e-07 28.9 0.3 1.5e-06 28.2 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4044 PF13253.6 EGO29081.1 - 0.1 12.2 0.8 0.17 11.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Pkinase PF00069.25 EGO29082.1 - 2e-30 106.0 0.0 4.2e-30 105.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29082.1 - 4.7e-14 52.3 0.0 7.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO29082.1 - 0.00013 20.9 0.0 0.0002 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO29082.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Spt20 PF12090.8 EGO29083.1 - 3.3 7.2 10.5 4.6 6.8 10.5 1.2 1 0 0 1 1 1 0 Spt20 family Ank_2 PF12796.7 EGO29084.1 - 8.6e-19 67.9 0.0 2.7e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO29084.1 - 3.8e-14 52.8 0.0 9.8e-05 22.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO29084.1 - 2.7e-12 46.7 0.5 0.01 16.1 0.0 3.5 2 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO29084.1 - 1.9e-11 43.1 0.1 0.18 12.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EGO29084.1 - 3e-10 40.1 0.0 0.008 16.6 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeat Neil1-DNA_bind PF09292.10 EGO29084.1 - 0.31 11.0 1.8 7.8 6.6 0.1 2.6 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind EHN PF06441.12 EGO29085.1 - 1.1e-33 115.8 0.4 6.4e-32 110.1 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EGO29085.1 - 1.8e-08 34.3 0.1 3e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO29085.1 - 0.0014 19.3 5.7 0.026 15.1 5.7 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arylsulfotrans PF05935.11 EGO29086.1 - 0.039 12.8 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) TGT PF01702.18 EGO29089.1 - 1e-29 103.8 0.0 1.2e-21 77.3 0.0 2.3 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Dimer_Tnp_hAT PF05699.14 EGO29091.1 - 0.00015 21.5 0.4 0.00023 20.9 0.4 1.5 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region zf-CCHC PF00098.23 EGO29093.1 - 8.4e-08 32.0 1.2 1.2e-07 31.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO29093.1 - 0.0087 15.6 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCHC_6 PF15288.6 EGO29093.1 - 0.13 12.1 1.5 0.22 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Kinetochor_Ybp2 PF08568.10 EGO29094.1 - 2.2e-15 56.2 0.1 1.1e-14 54.0 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin RIO1 PF01163.22 EGO29095.1 - 0.038 13.6 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Transp_cyt_pur PF02133.15 EGO29096.1 - 2e-38 132.4 30.6 8.6e-38 130.2 30.6 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mob1_phocein PF03637.17 EGO29097.1 - 2.3e-25 89.6 0.1 4.4e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family DUF4763 PF15960.5 EGO29097.1 - 0.32 10.3 2.5 0.66 9.2 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Palm_thioest PF02089.15 EGO29099.1 - 5.7e-07 29.6 0.0 6.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGO29099.1 - 1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO29099.1 - 5.7e-06 27.1 0.0 7.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO29099.1 - 7.3e-06 25.4 0.0 7.7e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGO29099.1 - 9.7e-06 25.9 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EGO29099.1 - 2.2e-05 24.3 0.0 7.5e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGO29099.1 - 2.4e-05 24.2 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.12 EGO29099.1 - 0.00057 19.0 0.2 0.0024 16.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF676 PF05057.14 EGO29099.1 - 0.0033 16.9 0.6 0.0047 16.5 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) UPF0227 PF05728.12 EGO29099.1 - 0.0062 16.5 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 EGO29099.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF4314 PF14192.6 EGO29099.1 - 0.068 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) Esterase PF00756.20 EGO29099.1 - 0.076 12.6 0.0 0.2 11.3 0.0 1.6 1 1 1 2 2 2 0 Putative esterase LCAT PF02450.15 EGO29099.1 - 0.09 11.9 0.0 0.18 10.9 0.0 1.4 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Acetyltransf_8 PF13523.6 EGO29100.1 - 8.9e-36 122.7 0.6 1.5e-35 122.0 0.6 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO29100.1 - 0.0017 19.0 0.2 0.0035 18.0 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SRP-alpha_N PF04086.13 EGO29101.1 - 8.3 6.2 9.8 8.6 6.2 9.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal R3H PF01424.22 EGO29102.1 - 1.5e-11 44.1 0.2 2.5e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EGO29102.1 - 5.6e-08 32.7 34.5 3.1e-07 30.3 11.7 14.4 15 0 0 15 15 15 7 NF-X1 type zinc finger NYD-SP28 PF14772.6 EGO29103.1 - 0.94 9.6 12.2 0.28 11.2 0.3 2.3 2 0 0 2 2 2 0 Sperm tail Adeno_IVa2 PF02456.15 EGO29104.1 - 0.011 14.5 0.6 0.74 8.5 0.1 2.0 1 1 1 2 2 2 0 Adenovirus IVa2 protein APH PF01636.23 EGO29107.1 - 1.3e-12 48.2 0.0 7.5e-12 45.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family APOBEC1 PF18769.1 EGO29107.1 - 0.1 12.8 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 APOBEC1 F-box-like PF12937.7 EGO29108.1 - 0.062 13.2 0.8 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 F-box-like DUF4140 PF13600.6 EGO29108.1 - 0.16 12.4 0.9 0.39 11.2 0.9 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TFIIA_gamma_N PF02268.16 EGO29109.1 - 3.2e-25 87.9 0.2 5.3e-25 87.2 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EGO29109.1 - 3.2e-22 78.4 0.0 5.2e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.14 EGO29109.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Scytalone dehydratase Amidase PF01425.21 EGO29110.1 - 3.9e-95 319.5 0.0 4.9e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Amidase SGS PF05002.15 EGO29111.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 SGS domain Chlam_OMP6 PF03504.13 EGO29112.1 - 0.053 13.8 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 TFIIE_alpha PF02002.17 EGO29112.1 - 0.065 13.1 0.0 0.087 12.7 0.0 1.3 1 1 0 1 1 1 0 TFIIE alpha subunit DUF2568 PF10823.8 EGO29113.1 - 0.00079 19.7 1.9 0.00094 19.4 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2568) DUF5345 PF17280.2 EGO29113.1 - 0.084 12.9 0.8 0.084 12.9 0.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Herpes_US9 PF06072.11 EGO29113.1 - 0.49 10.3 6.5 0.083 12.8 1.6 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Amastin PF07344.11 EGO29114.1 - 0.0013 18.5 1.4 0.0021 17.9 1.4 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein AgrB PF04647.15 EGO29114.1 - 0.66 9.3 7.1 0.032 13.6 1.5 1.6 2 0 0 2 2 2 0 Accessory gene regulator B RRM_1 PF00076.22 EGO29115.1 - 3.7e-19 68.3 0.0 2.5e-10 40.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO29115.1 - 0.018 15.2 0.0 0.37 10.9 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif PRP1_N PF06424.12 EGO29115.1 - 0.068 13.6 0.6 0.21 12.0 0.6 1.8 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PI-TkoII_IV PF18714.1 EGO29115.1 - 0.23 10.9 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV GPI-anchored PF10342.9 EGO29117.1 - 0.00041 21.0 1.3 0.00041 21.0 1.3 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4307 PF14155.6 EGO29118.1 - 0.27 11.1 2.1 0.23 11.3 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) AA_permease_2 PF13520.6 EGO29119.1 - 4.2e-72 243.3 44.1 5.4e-72 242.9 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO29119.1 - 6.6e-12 44.8 38.4 1.2e-11 43.9 38.4 1.4 1 1 0 1 1 1 1 Amino acid permease COX6C PF02937.15 EGO29119.1 - 0.62 10.2 6.5 2.6 8.2 0.0 4.2 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIc Pro_isomerase PF00160.21 EGO29120.1 - 2.2e-43 148.2 1.0 2.5e-43 148.1 1.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4097 PF13349.6 EGO29121.1 - 0.00042 19.7 0.0 0.012 14.9 0.0 2.6 1 1 0 1 1 1 1 Putative adhesin GluRS_N PF18466.1 EGO29121.1 - 0.35 11.3 2.5 0.45 10.9 0.1 2.4 3 0 0 3 3 3 0 Glutamate--tRNA ligase N-terminal domain GH114_assoc PF14741.6 EGO29123.1 - 0.027 14.7 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain Ski2_N PF17911.1 EGO29123.1 - 0.031 14.1 0.6 0.065 13.0 0.6 1.5 1 0 0 1 1 1 0 Ski2 N-terminal region Ribosomal_L18A PF01775.17 EGO29125.1 - 9e-56 187.2 0.3 1.1e-55 186.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CSN5_C PF18323.1 EGO29126.1 - 1e-30 106.5 2.5 1.8e-30 105.7 2.5 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 EGO29126.1 - 5.7e-30 103.7 0.1 1.2e-29 102.7 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGO29126.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Oxidored-like PF09791.9 EGO29127.1 - 4.7e-17 61.4 0.6 8.5e-17 60.6 0.6 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal COesterase PF00135.28 EGO29128.1 - 8.1e-86 288.9 0.0 9.1e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO29128.1 - 0.00021 21.2 4.7 0.005 16.7 0.1 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold EKR PF10371.9 EGO29128.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function FHA PF00498.26 EGO29129.1 - 2.4e-11 43.8 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO29129.1 - 0.00036 20.8 0.0 0.0006 20.1 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ribonucleas_3_3 PF14622.6 EGO29130.1 - 1.1e-16 61.1 0.1 5.5e-09 36.3 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGO29130.1 - 0.0022 18.6 0.0 0.004 17.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain BTB PF00651.31 EGO29131.1 - 2.8e-08 34.0 0.0 5.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGO29132.1 - 4.8e-09 36.4 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Amidase PF01425.21 EGO29133.1 - 5.4e-87 292.6 0.0 3.6e-74 250.4 0.0 2.4 2 1 0 2 2 2 2 Amidase Amidase PF01425.21 EGO29134.1 - 2.2e-98 330.1 0.0 2.7e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 Amidase SET PF00856.28 EGO29135.1 - 6.5e-12 46.2 0.0 1.6e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGO29135.1 - 1.7e-06 28.0 11.2 1.7e-06 28.0 11.2 3.2 2 1 1 3 3 3 1 MYND finger Anti-TRAP PF15777.5 EGO29135.1 - 4.5 7.3 12.8 0.12 12.4 4.4 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CH PF00307.31 EGO29136.1 - 1.4e-75 250.5 0.0 2.2e-19 69.7 0.0 4.7 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGO29136.1 - 9.5e-07 28.6 0.0 1.9 8.4 0.0 4.5 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.6 EGO29136.1 - 0.12 12.9 0.0 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair GST_C_2 PF13410.6 EGO29137.1 - 0.00077 19.4 0.2 0.0017 18.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGO29137.1 - 0.11 13.1 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.21 EGO29138.1 - 1.4e-18 67.3 0.0 1.6e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PAC3 PF10178.9 EGO29139.1 - 0.29 11.3 1.6 3.6 7.8 1.6 2.5 1 1 0 1 1 1 0 Proteasome assembly chaperone 3 US30 PF17624.2 EGO29139.1 - 0.85 8.6 2.0 1.3 8.1 2.0 1.2 1 0 0 1 1 1 0 Family of unknown function His_Phos_1 PF00300.22 EGO29140.1 - 5.3e-22 78.4 0.0 7.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cauli_VI PF01693.16 EGO29144.1 - 5.5e-06 26.6 0.2 8.8e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Mito_fiss_reg PF05308.11 EGO29144.1 - 0.2 11.7 4.5 0.26 11.4 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Abhydrolase_6 PF12697.7 EGO29145.1 - 3.2e-12 47.5 0.2 4.8e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Asp PF00026.23 EGO29146.1 - 8.7e-28 97.6 7.0 1.2e-26 93.9 7.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGO29146.1 - 3.1e-06 27.7 2.4 0.00031 21.3 0.4 2.6 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EGO29146.1 - 7.9e-05 23.1 0.5 0.012 16.1 0.1 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 EGO29146.1 - 0.00067 19.9 0.9 0.1 12.8 0.1 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGO29146.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal FlhC PF05280.11 EGO29147.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) DUF3824 PF12868.7 EGO29149.1 - 0.0039 17.9 2.7 0.0054 17.4 2.7 1.1 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) Peroxin-13_N PF04088.13 EGO29164.1 - 7.7e-45 152.7 0.1 1.3e-44 152.0 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 EGO29164.1 - 5.4e-10 38.7 1.1 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGO29164.1 - 1.5e-09 37.4 0.0 2.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO29164.1 - 1.1e-07 31.6 0.4 2.1e-07 30.7 0.4 1.5 1 1 0 1 1 1 1 Variant SH3 domain PRCC PF10253.9 EGO29164.1 - 0.014 16.2 1.4 0.029 15.1 0.7 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CHAT PF12770.7 EGO29165.1 - 2.4e-24 86.2 0.1 6e-24 85.0 0.1 1.6 1 1 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EGO29165.1 - 1.3e-09 37.6 16.1 0.084 12.8 0.0 9.2 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO29165.1 - 4.8e-09 36.4 23.2 0.77 10.1 0.2 10.8 6 5 6 12 12 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO29165.1 - 6.6e-07 28.9 5.5 9.2 6.1 0.0 7.5 6 1 0 6 6 6 3 TPR repeat TPR_1 PF00515.28 EGO29165.1 - 0.0047 16.7 21.3 8.7 6.4 0.0 11.0 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO29165.1 - 0.09 13.4 8.8 7.3 7.3 0.0 5.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO29165.1 - 0.23 11.7 11.8 57 4.2 0.0 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.19 EGO29170.1 - 9.7e-66 222.0 0.0 1.3e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain dCache_3 PF14827.6 EGO29170.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Aminotran_5 PF00266.19 EGO29170.1 - 0.04 12.9 0.0 0.074 12.0 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 EGO29170.1 - 0.049 12.4 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Ribosomal_L16 PF00252.18 EGO29171.1 - 2.7e-37 127.7 0.3 3.1e-37 127.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.10 EGO29172.1 - 1.6e-73 247.2 6.0 2.8e-73 246.3 6.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGO29172.1 - 5e-43 146.7 0.7 1.6e-42 145.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Snurportin1 PF11538.8 EGO29173.1 - 9.7e-05 22.5 3.1 9.7e-05 22.5 3.1 2.4 2 0 0 2 2 2 1 Snurportin1 DUF3420 PF11900.8 EGO29173.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) U1snRNP70_N PF12220.8 EGO29173.1 - 2.4 8.9 8.5 1.1 9.9 2.6 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MFS_1 PF07690.16 EGO29174.1 - 4.2e-26 91.7 33.8 5.6e-26 91.3 33.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO29174.1 - 0.00065 18.2 5.3 0.00091 17.8 5.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L32p PF01783.23 EGO29175.1 - 6.1e-17 61.6 6.3 8.3e-17 61.2 5.5 1.6 1 1 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 EGO29175.1 - 0.00027 20.8 0.1 0.00046 20.1 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 MatE PF01554.18 EGO29178.1 - 5.7e-52 175.6 27.2 3e-27 95.3 6.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGO29178.1 - 1.5e-06 28.4 9.6 1.5e-06 28.4 9.6 4.2 2 2 3 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Bac_surface_Ag PF01103.23 EGO29179.1 - 8.3e-45 153.7 0.3 1e-44 153.4 0.3 1.1 1 0 0 1 1 1 1 Surface antigen IBN_N PF03810.19 EGO29179.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Importin-beta N-terminal domain Ribosomal_S8 PF00410.19 EGO29180.1 - 3.5e-11 43.1 0.0 1.8e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 TAL_FSA PF00923.19 EGO29181.1 - 6.2e-33 114.4 0.1 4e-32 111.7 0.1 1.9 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CRIM PF16978.5 EGO29182.1 - 4.3e-42 143.6 0.0 2.3e-41 141.2 0.0 2.2 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGO29182.1 - 3.6e-34 117.3 0.7 6.9e-34 116.4 0.7 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 EGO29182.1 - 0.00021 21.3 0.0 0.002 18.2 0.0 2.5 2 0 0 2 2 2 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 EGO29182.1 - 0.00058 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain AAA_12 PF13087.6 EGO29183.1 - 1.2e-31 109.9 0.1 1.3e-31 109.7 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO29183.1 - 0.0067 16.2 0.0 0.028 14.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGO29183.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 EGO29184.1 - 4.3e-42 144.0 0.0 5.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGO29184.1 - 0.011 15.6 0.4 0.061 13.2 0.4 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EGO29184.1 - 0.048 13.4 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_trans_NIPA PF05653.14 EGO29185.1 - 2.1e-94 315.9 12.3 2.5e-94 315.7 12.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGO29185.1 - 0.0099 16.1 3.5 0.0099 16.1 3.5 3.2 3 0 0 3 3 3 1 EamA-like transporter family Creatinase_N_2 PF16189.5 EGO29186.1 - 1.1e-50 171.9 0.0 6.9e-50 169.3 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGO29186.1 - 2.5e-45 154.7 0.0 3.5e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EGO29186.1 - 2.5e-24 85.1 0.2 7.6e-24 83.6 0.2 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EGO29186.1 - 1.5e-21 77.5 0.0 8.3e-17 62.1 0.0 2.5 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF3243 PF11588.8 EGO29186.1 - 0.087 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) G-alpha PF00503.20 EGO29187.1 - 1.9e-123 412.1 0.0 2.3e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO29187.1 - 1.4e-05 24.6 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AA_kinase PF00696.28 EGO29189.1 - 2.1e-36 125.8 0.0 4.9e-36 124.5 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EGO29189.1 - 1.7e-11 43.7 0.4 2.5e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EGO29189.1 - 2.5e-09 36.8 1.1 4.4e-07 29.6 0.1 2.8 3 0 0 3 3 3 2 ACT domain ChAPs PF09295.10 EGO29190.1 - 9.9e-148 492.3 0.0 4.8e-146 486.8 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EGO29190.1 - 7e-07 29.7 0.3 0.0018 18.7 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO29190.1 - 4.6e-06 26.3 2.0 2 8.8 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO29190.1 - 0.0052 17.4 5.0 0.78 10.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO29190.1 - 0.0074 16.4 5.5 1.1 9.7 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGO29190.1 - 0.0084 15.4 4.6 0.97 8.6 0.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO29190.1 - 0.01 16.1 2.7 2.2 8.5 0.9 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 EGO29190.1 - 0.013 14.4 1.3 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EGO29190.1 - 0.05 14.4 6.2 3.7 8.6 0.0 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGO29190.1 - 0.055 13.2 0.1 0.57 9.9 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EGO29190.1 - 0.18 11.9 0.8 3.1 8.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO29190.1 - 0.59 10.1 4.7 45 4.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 EGO29193.1 - 7.4e-93 311.4 0.0 1.2e-92 310.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGO29193.1 - 5.6e-65 219.4 0.0 1.1e-64 218.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EGO29193.1 - 9.6e-54 182.8 0.0 1.4e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 EGO29193.1 - 2.5e-34 119.2 0.0 4.7e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGO29193.1 - 1.3e-33 116.4 0.1 3.1e-33 115.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EGO29193.1 - 1.8e-31 108.6 0.6 7.2e-31 106.7 0.1 2.5 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EGO29193.1 - 7.1e-22 78.0 0.0 1.6e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 EGO29193.1 - 1.5e-18 67.8 0.0 3.1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EGO29193.1 - 7.3e-16 58.3 4.7 4.1e-08 33.5 0.0 3.5 4 0 0 4 4 3 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGO29193.1 - 3.2e-10 40.4 0.0 8.5e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 EGO29193.1 - 1.5e-07 32.3 0.1 5.3e-07 30.5 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 EGO29193.1 - 0.0005 19.5 0.7 0.005 16.2 0.1 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EGO29193.1 - 0.0011 19.7 0.3 0.032 14.8 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO29193.1 - 0.0048 16.2 0.1 0.045 13.0 0.0 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ACP_syn_III PF08545.10 EGO29193.1 - 0.0081 16.0 0.3 0.023 14.5 0.3 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 EGO29193.1 - 0.046 13.7 0.9 0.73 9.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Abhydrolase_1 PF00561.20 EGO29193.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Transp_cyt_pur PF02133.15 EGO29194.1 - 2.9e-29 102.1 41.5 6.2e-29 101.0 41.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 EGO29195.1 - 2e-17 63.2 34.3 2e-17 63.2 34.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO29195.1 - 3.5e-12 46.3 8.6 3.5e-12 46.3 8.6 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 UNC-93 PF05978.16 EGO29196.1 - 1.6e-15 57.1 7.4 1.6e-15 57.1 7.4 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGO29196.1 - 8.9e-14 51.2 33.6 1.5e-13 50.4 33.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_7 PF08395.12 EGO29196.1 - 0.0034 16.6 1.6 0.0034 16.6 1.6 2.5 4 0 0 4 4 4 1 7tm Chemosensory receptor NCE101 PF11654.8 EGO29196.1 - 1.1 9.0 3.5 27 4.6 0.0 3.5 4 0 0 4 4 4 0 Non-classical export protein 1 UNC-93 PF05978.16 EGO29197.1 - 3.3e-14 52.9 6.4 3.3e-14 52.9 6.4 2.4 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGO29197.1 - 6.5e-12 45.0 33.7 6.5e-12 45.0 33.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO29198.1 - 3.7e-15 56.0 7.4 3.7e-15 56.0 7.4 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGO29198.1 - 1.3e-13 50.6 36.1 2.2e-13 49.9 36.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_7 PF08395.12 EGO29198.1 - 0.0092 15.2 2.2 0.0092 15.2 2.2 2.3 3 0 0 3 3 3 1 7tm Chemosensory receptor Ion_trans_2 PF07885.16 EGO29201.1 - 2e-28 98.1 34.1 2.7e-17 62.5 10.4 3.1 3 0 0 3 3 3 2 Ion channel DUF2207 PF09972.9 EGO29201.1 - 0.57 8.9 5.8 3.7 6.2 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.7 EGO29202.1 - 2.5e-18 66.5 0.4 4.3e-11 43.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO29202.1 - 9.2e-14 51.6 0.2 1.3e-10 41.6 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO29202.1 - 1.2e-13 50.8 0.3 5.7e-06 26.5 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGO29202.1 - 2.3e-11 43.7 0.1 1.2e-07 31.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO29202.1 - 3.3e-10 39.3 0.0 0.0032 17.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Baculo_RING PF05883.11 EGO29204.1 - 0.058 13.4 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_2 PF13639.6 EGO29205.1 - 1.2e-06 28.7 7.2 2.5e-06 27.7 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EGO29205.1 - 8.8e-06 25.8 3.9 1.9e-05 24.8 3.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EGO29205.1 - 0.0039 17.5 6.3 0.0098 16.2 6.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO29205.1 - 0.0043 17.1 1.7 0.0093 16.0 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3598 PF12204.8 EGO29205.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) zf-C3HC4 PF00097.25 EGO29205.1 - 0.1 12.5 7.6 0.19 11.7 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO29205.1 - 0.11 12.3 7.6 0.28 11.0 7.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGO29205.1 - 0.18 11.5 4.6 0.38 10.4 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EGO29205.1 - 0.23 11.6 6.0 0.53 10.4 6.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EGO29205.1 - 0.26 11.6 8.1 0.21 11.9 6.3 1.9 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.22 EGO29205.1 - 1.1 9.2 6.2 2.4 8.1 6.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD PF00270.29 EGO29206.1 - 7.5e-36 123.5 0.0 1.3e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO29206.1 - 1.1e-18 67.6 0.1 4.3e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO29206.1 - 0.004 17.2 0.0 0.023 14.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CTP_synth_N PF06418.14 EGO29207.1 - 1.6e-121 404.6 0.1 2.1e-121 404.3 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGO29207.1 - 3.3e-50 170.5 0.0 5.5e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGO29207.1 - 0.0012 18.6 0.0 0.08 12.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 EGO29207.1 - 0.05 13.7 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 EGO29208.1 - 2.7e-42 144.3 0.2 1.1e-15 58.2 0.0 4.9 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 EGO29208.1 - 5e-38 130.7 0.0 1.2e-37 129.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO29208.1 - 5e-25 88.8 23.1 3.6e-22 79.4 0.0 6.1 6 0 0 6 6 5 2 AAA domain AAA_lid_6 PF17866.1 EGO29208.1 - 1.5e-22 79.6 4.1 5.1e-10 39.4 0.1 3.9 3 0 0 3 3 3 3 AAA lid domain AAA_19 PF13245.6 EGO29208.1 - 7.8e-14 52.2 4.1 0.0009 19.6 0.0 6.0 4 2 0 4 4 4 4 AAA domain AAA_30 PF13604.6 EGO29208.1 - 1.1e-11 44.8 17.1 0.02 14.6 0.0 7.3 7 0 0 7 7 7 4 AAA domain AAA_5 PF07728.14 EGO29208.1 - 2.9e-10 40.3 0.6 0.013 15.5 0.1 4.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGO29208.1 - 3.5e-09 36.3 0.0 0.33 10.3 0.0 4.4 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EGO29208.1 - 4.7e-09 36.3 0.0 1.2 8.8 0.0 5.2 5 0 0 5 5 5 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGO29208.1 - 5.4e-08 33.2 9.7 0.08 13.2 0.2 6.9 5 3 0 5 5 4 2 AAA domain AAA_24 PF13479.6 EGO29208.1 - 1.4e-07 31.4 1.7 0.38 10.4 0.0 4.2 4 0 0 4 4 4 3 AAA domain RuvB_N PF05496.12 EGO29208.1 - 3.1e-07 30.3 0.1 0.74 9.5 0.0 4.0 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO29208.1 - 5.9e-07 30.0 5.9 0.23 11.9 0.1 5.3 4 0 0 4 4 4 2 AAA ATPase domain IstB_IS21 PF01695.17 EGO29208.1 - 2.2e-06 27.6 0.1 2.7 7.7 0.0 4.1 4 0 0 4 4 3 3 IstB-like ATP binding protein ResIII PF04851.15 EGO29208.1 - 3e-06 27.3 3.5 0.022 14.8 0.1 4.8 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EGO29208.1 - 4e-06 27.2 0.1 1.8 9.0 0.0 4.2 4 0 0 4 4 3 2 RNA helicase AAA_18 PF13238.6 EGO29208.1 - 1.1e-05 25.9 4.3 3.7 8.1 0.1 5.3 4 0 0 4 4 4 1 AAA domain Torsin PF06309.11 EGO29208.1 - 0.00012 22.1 0.1 5.6 7.1 0.0 4.5 4 0 0 4 4 4 0 Torsin Sigma54_activat PF00158.26 EGO29208.1 - 0.00013 21.7 0.9 3.2 7.4 0.0 4.3 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_33 PF13671.6 EGO29208.1 - 0.0003 21.0 10.5 1.3 9.1 0.1 4.1 4 0 0 4 4 3 3 AAA domain AAA_7 PF12775.7 EGO29208.1 - 0.00053 19.5 1.4 7.3 6.1 0.1 4.3 4 0 0 4 4 4 0 P-loop containing dynein motor region SRP54 PF00448.22 EGO29208.1 - 0.012 15.2 2.4 0.68 9.5 0.0 3.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 EGO29208.1 - 0.014 15.8 11.1 2.1 8.8 0.1 4.8 4 0 0 4 4 3 0 AAA domain MCM PF00493.23 EGO29208.1 - 0.017 14.2 0.0 1.2 8.2 0.0 3.0 3 0 0 3 3 3 0 MCM P-loop domain NTPase_1 PF03266.15 EGO29208.1 - 0.018 14.9 1.5 22 4.9 0.1 3.7 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 EGO29208.1 - 0.019 15.2 18.2 0.76 10.0 0.0 5.1 5 0 0 5 5 3 0 AAA domain Sigma54_activ_2 PF14532.6 EGO29208.1 - 0.025 14.7 0.1 3.5 7.8 0.0 3.6 4 0 0 4 4 3 0 Sigma-54 interaction domain Nrap_D2 PF17403.2 EGO29208.1 - 0.035 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain KTI12 PF08433.10 EGO29208.1 - 0.078 12.4 2.8 18 4.7 0.0 4.0 4 0 0 4 4 4 0 Chromatin associated protein KTI12 TsaE PF02367.17 EGO29208.1 - 0.094 12.7 4.4 9.3 6.3 0.0 3.6 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 EGO29208.1 - 0.2 11.1 0.1 0.84 9.0 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein ADK PF00406.22 EGO29208.1 - 0.24 11.5 1.4 47 4.1 0.1 3.8 3 0 0 3 3 3 0 Adenylate kinase ABC_tran PF00005.27 EGO29208.1 - 0.77 10.3 7.7 26 5.3 0.0 4.6 5 0 0 5 5 4 0 ABC transporter DUF2075 PF09848.9 EGO29208.1 - 2.4 7.3 18.3 33 3.6 0.4 7.4 6 3 0 6 6 6 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 EGO29209.1 - 3.8e-15 56.0 17.5 0.0011 19.8 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29209.1 - 3.4e-07 30.5 0.7 0.043 14.1 0.1 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO29209.1 - 0.00051 19.1 0.0 0.2 10.6 0.0 3.5 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pheromone PF08015.11 EGO29209.1 - 4.1 8.5 8.3 13 6.9 1.4 3.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Cellulase PF00150.18 EGO29210.1 - 6.4e-46 157.0 0.8 1.1e-45 156.3 0.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 EGO29211.1 - 2.7e-46 158.3 0.3 3.5e-46 157.9 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EGO29211.1 - 6.9e-12 45.1 5.0 6.9e-12 45.1 5.0 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain WD40 PF00400.32 EGO29212.1 - 3.9e-51 169.9 26.1 3e-10 40.5 2.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29212.1 - 3.9e-17 62.3 4.7 0.0012 19.1 0.0 5.9 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO29212.1 - 2.2e-05 23.6 1.3 5.1 5.9 0.2 5.0 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGO29212.1 - 0.17 10.6 1.1 5.7 5.6 0.1 3.5 3 1 2 5 5 5 0 Nup133 N terminal like Aminotran_1_2 PF00155.21 EGO29213.1 - 2e-58 198.3 0.0 2.2e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGO29213.1 - 0.0012 17.7 0.0 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase Tox-ART-HYE1 PF15634.6 EGO29213.1 - 0.042 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Bin3 PF06859.12 EGO29214.1 - 2.6e-37 127.7 0.0 3.8e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 EGO29214.1 - 9.2e-13 48.7 0.1 2.3e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGO29214.1 - 3.1e-12 46.6 0.0 4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO29214.1 - 4.9e-12 45.9 0.0 9e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGO29214.1 - 3.1e-10 40.6 0.1 0.00092 19.8 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGO29214.1 - 2.8e-08 34.4 0.0 0.00084 20.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 EGO29214.1 - 9.9e-05 21.9 0.0 0.007 15.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.7 EGO29214.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO29214.1 - 0.011 15.3 0.0 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 EGO29214.1 - 0.026 13.9 0.0 0.065 12.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EGO29214.1 - 0.041 13.2 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGO29214.1 - 0.041 13.2 0.2 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EGO29214.1 - 0.042 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 EGO29214.1 - 0.059 12.3 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EGO29214.1 - 0.15 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-MYND PF01753.18 EGO29215.1 - 1.5e-09 37.8 14.9 3e-09 36.8 14.9 1.5 1 0 0 1 1 1 1 MYND finger Desulfoferrod_N PF06397.12 EGO29215.1 - 0.61 9.7 3.9 0.18 11.4 0.6 1.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-C6H2 PF15801.5 EGO29215.1 - 1.3 9.4 10.6 2.7 8.4 10.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGO29216.1 - 1.1e-08 35.0 13.0 2.8e-08 33.7 13.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO29216.1 - 0.34 11.2 9.1 0.8 10.1 9.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SAD_SRA PF02182.17 EGO29217.1 - 1.2e-40 138.8 0.0 2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Glyco_hydro_18 PF00704.28 EGO29218.1 - 2.5e-55 188.4 1.9 3.1e-55 188.1 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGO29218.1 - 0.051 13.0 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 JTB PF05439.12 EGO29221.1 - 7.1e-05 22.8 0.1 0.06 13.4 0.0 2.2 2 0 0 2 2 2 2 Jumping translocation breakpoint protein (JTB) SRP19 PF01922.17 EGO29222.1 - 5.8e-28 97.7 0.0 8.7e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein COesterase PF00135.28 EGO29223.1 - 6.3e-55 187.0 0.0 1.8e-49 169.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family DUF1749 PF08538.10 EGO29223.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 EGO29223.1 - 0.026 14.4 0.3 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold MAPEG PF01124.18 EGO29224.1 - 4.9e-23 81.4 2.1 5.6e-23 81.3 2.1 1.0 1 0 0 1 1 1 1 MAPEG family SHMT PF00464.19 EGO29225.1 - 3.8e-167 555.9 0.0 4.5e-167 555.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGO29225.1 - 0.0027 17.0 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase DUF3437 PF11919.8 EGO29226.1 - 0.077 12.9 0.4 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF5444 PF17519.2 EGO29226.1 - 0.35 10.9 1.8 1.3 9.0 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5444) Cu-oxidase PF00394.22 EGO29227.1 - 1e-35 123.2 1.7 2.3e-33 115.6 0.1 3.7 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO29227.1 - 8.2e-35 119.4 4.6 9e-32 109.6 0.6 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO29227.1 - 5.7e-34 116.8 0.3 5.7e-34 116.8 0.3 2.7 4 0 0 4 4 4 1 Multicopper oxidase Ureidogly_lyase PF04115.12 EGO29227.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Ureidoglycolate lyase FTR1 PF03239.14 EGO29228.1 - 3.9e-63 213.5 7.6 4.6e-63 213.2 7.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family zf-C2H2_6 PF13912.6 EGO29229.1 - 9.6e-45 149.8 91.2 2.9e-06 27.1 0.3 14.8 11 4 4 15 15 15 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO29229.1 - 3.6e-27 94.1 85.4 0.0017 18.6 0.4 14.9 15 0 0 15 15 14 9 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGO29229.1 - 5.8e-22 76.5 117.9 0.0019 18.9 0.3 17.9 16 2 2 18 18 17 10 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO29229.1 - 6.1e-19 67.4 105.9 0.0025 18.2 0.2 16.4 16 0 0 16 16 15 11 Zinc finger, C2H2 type zf-met PF12874.7 EGO29229.1 - 3.1e-08 33.7 97.6 0.0029 18.0 1.0 15.4 16 0 0 16 16 14 6 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 EGO29229.1 - 2.1e-05 24.2 13.0 1.6 8.6 0.0 6.3 7 0 0 7 7 6 3 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 EGO29229.1 - 2.4e-05 24.1 0.4 0.01 15.7 0.0 12.8 15 0 0 15 15 14 2 zinc-finger of a C2HC-type zf-C3HC4_2 PF13923.6 EGO29229.1 - 8e-05 22.4 13.5 8e-05 22.4 13.5 7.6 12 1 1 13 13 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO29229.1 - 0.00012 21.9 13.4 0.00012 21.9 13.4 8.2 8 3 0 8 8 6 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO29229.1 - 0.0015 18.4 13.7 0.0015 18.4 13.7 8.3 7 3 2 9 9 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO29229.1 - 0.0025 18.1 13.3 0.0025 18.1 13.3 8.5 6 2 2 8 8 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO29229.1 - 0.005 16.7 12.8 0.005 16.7 12.8 9.1 5 1 3 9 9 9 2 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 EGO29229.1 - 0.005 16.6 7.3 3 7.7 0.1 5.9 4 0 0 4 4 4 1 C2H2-type zinc-finger domain Ribosomal_L34e PF01199.18 EGO29229.1 - 0.0082 16.4 0.4 0.0082 16.4 0.4 5.8 4 2 3 8 8 8 1 Ribosomal protein L34e zf-RING_6 PF14835.6 EGO29229.1 - 0.023 14.5 6.2 0.14 12.1 6.2 2.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf_C2H2_ZHX PF18387.1 EGO29229.1 - 0.047 13.3 0.5 0.047 13.3 0.5 13.7 4 2 10 14 14 14 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 EGO29229.1 - 0.06 13.1 0.2 0.06 13.1 0.2 12.2 14 0 0 14 14 13 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 EGO29229.1 - 0.33 11.5 0.1 0.33 11.5 0.1 15.4 17 1 0 17 17 15 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 EGO29229.1 - 0.65 10.4 101.8 0.24 11.8 14.3 12.5 3 2 8 11 11 10 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 EGO29229.1 - 2 8.6 21.5 4.6 7.4 0.2 7.2 6 3 3 9 9 9 0 Zic proteins zinc finger domain DUF434 PF04256.12 EGO29230.1 - 0.08 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF434) zf-CCHC_3 PF13917.6 EGO29232.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO29232.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO29232.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO29232.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVP_2 PF08284.11 EGO29233.1 - 1.8e-05 24.5 0.0 0.025 14.3 0.0 2.1 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO29233.1 - 0.00094 19.7 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO29233.1 - 0.0023 18.5 0.0 0.0031 18.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Siva PF05458.12 EGO29233.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF5475 PF17569.2 EGO29233.1 - 0.18 12.1 0.0 0.41 11.0 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5475) Retrotrans_gag PF03732.17 EGO29234.1 - 1.6e-05 25.0 0.8 5.9e-05 23.3 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO29234.1 - 9.2e-05 22.3 3.1 0.00022 21.1 3.1 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF4336 PF14234.6 EGO29236.1 - 4.9e-14 52.3 0.1 9.8e-08 31.6 0.0 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Hira PF07569.11 EGO29237.1 - 5.5e-53 180.0 0.7 2e-52 178.1 0.1 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EGO29237.1 - 4.6e-29 100.1 20.2 9.2e-06 26.3 0.1 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29237.1 - 3.1e-12 46.6 1.4 0.16 12.3 0.0 6.8 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain SoxZ PF08770.11 EGO29237.1 - 0.15 11.8 0.1 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Sulphur oxidation protein SoxZ MFS_1 PF07690.16 EGO29238.1 - 4.5e-13 48.9 12.6 4.1e-12 45.7 12.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C3HC4_3 PF13920.6 EGO29239.1 - 3.4e-10 39.6 6.3 3.4e-10 39.6 6.3 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.8 EGO29239.1 - 7e-10 38.9 16.8 0.00058 20.1 0.3 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C3HC4_2 PF13923.6 EGO29239.1 - 9.2e-10 38.2 9.2 9.2e-10 38.2 9.2 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO29239.1 - 4.9e-09 36.4 9.1 4.9e-09 36.4 9.1 3.1 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGO29239.1 - 2.4e-07 30.5 8.7 2.4e-07 30.5 8.7 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO29239.1 - 1e-06 28.6 9.8 1e-06 28.6 9.8 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO29239.1 - 1.3e-06 28.4 3.7 1.3e-06 28.4 3.7 3.1 3 1 1 4 4 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO29239.1 - 3.8e-05 23.5 7.8 3.8e-05 23.5 7.8 3.3 2 2 1 4 4 4 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGO29239.1 - 0.00018 21.7 8.1 0.00018 21.7 8.1 2.8 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-C2H2_4 PF13894.6 EGO29239.1 - 0.00028 21.4 25.5 0.19 12.7 0.2 6.1 5 1 1 6 6 6 3 C2H2-type zinc finger TerY_C PF15616.6 EGO29239.1 - 0.00038 20.6 1.7 0.00038 20.6 1.7 2.3 2 1 1 3 3 3 1 TerY-C metal binding domain zf-C3HC4_4 PF15227.6 EGO29239.1 - 0.00042 20.4 8.0 0.00042 20.4 8.0 3.9 2 2 2 4 4 3 1 zinc finger of C3HC4-type, RING zf-met PF12874.7 EGO29239.1 - 0.00064 20.0 24.8 0.059 13.8 0.1 5.1 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-RING_6 PF14835.6 EGO29239.1 - 0.0014 18.4 2.9 0.0045 16.8 2.9 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Rtf2 PF04641.12 EGO29239.1 - 0.0024 17.3 1.0 0.0024 17.3 1.0 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 EGO29239.1 - 0.0029 17.6 2.0 0.0029 17.6 2.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EGO29239.1 - 0.012 15.4 3.8 0.029 14.2 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nop14 PF04147.12 EGO29239.1 - 0.13 10.5 3.2 0.15 10.2 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2 PF00096.26 EGO29239.1 - 0.42 11.2 0.3 0.42 11.2 0.3 5.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type DUF1272 PF06906.11 EGO29239.1 - 0.65 10.1 19.8 4.1 7.6 0.5 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1272) zf-H2C2_2 PF13465.6 EGO29239.1 - 1.2 9.7 22.4 2.7 8.6 1.8 5.3 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 EGO29239.1 - 8.9 6.7 17.6 4.6 7.6 7.7 4.1 2 2 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 EGO29240.1 - 1.2e-42 146.2 0.0 1.5e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29240.1 - 1e-39 136.4 0.0 1.3e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO29240.1 - 0.05 13.5 0.0 0.24 11.3 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO29240.1 - 0.06 12.1 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGO29240.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 EGO29241.1 - 1.3e-37 129.6 0.0 2.3e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO29241.1 - 7.9e-35 120.5 0.0 1.8e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain NUC130_3NT PF08158.12 EGO29241.1 - 0.65 10.4 3.0 35 4.8 0.1 3.0 3 0 0 3 3 3 0 NUC130/3NT domain STE3 PF02076.15 EGO29242.1 - 4.8e-96 321.4 19.0 5.9e-96 321.1 19.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3094 PF11293.8 EGO29242.1 - 1.1 9.1 3.8 4.1 7.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) Cerato-platanin PF07249.12 EGO29243.1 - 0.018 15.2 1.2 0.49 10.5 0.1 2.3 1 1 1 2 2 2 0 Cerato-platanin GST_C_5 PF16865.5 EGO29245.1 - 0.00025 21.6 0.1 0.00051 20.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO29245.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO29245.1 - 0.0075 16.6 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO29245.1 - 0.012 16.0 0.1 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO29245.1 - 0.063 13.6 0.3 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO29245.1 - 0.073 13.3 0.1 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 EGO29247.1 - 1.8e-18 67.0 0.0 9.6e-18 64.6 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO29247.1 - 1.3e-15 57.7 0.0 1.2e-13 51.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGO29247.1 - 9.1e-11 42.3 1.0 2.5e-10 40.9 0.6 2.0 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EGO29247.1 - 1.7e-05 24.9 0.0 4.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 EGO29247.1 - 0.0001 21.8 0.1 0.00032 20.1 0.0 1.8 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD AAA_22 PF13401.6 EGO29247.1 - 0.02 15.2 0.6 0.14 12.4 0.3 2.6 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 EGO29247.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DctP PF03480.13 EGO29247.1 - 0.17 11.2 0.0 19 4.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 BES1_N PF05687.13 EGO29248.1 - 6.4 7.2 9.2 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal CPSF_A PF03178.15 EGO29249.1 - 4e-83 279.4 0.0 9.3e-83 278.2 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EGO29249.1 - 9e-20 70.8 0.0 2.3e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ATP_bind_1 PF03029.17 EGO29250.1 - 7.1e-74 248.6 0.0 8.7e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EGO29250.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNase_H PF00075.24 EGO29251.1 - 2e-10 41.0 0.0 1e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 RNase H zf-Mss51 PF13824.6 EGO29251.1 - 0.014 15.4 0.3 0.026 14.6 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TP_methylase PF00590.20 EGO29252.1 - 1.9e-19 70.5 0.0 2.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PLRV_ORF5 PF01690.17 EGO29252.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein COesterase PF00135.28 EGO29253.1 - 4.1e-13 49.0 0.0 9.9e-13 47.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO29253.1 - 7.5e-12 45.5 0.1 2e-11 44.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO29253.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EGO29253.1 - 0.048 14.2 0.4 0.08 13.5 0.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO29253.1 - 0.17 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UDG PF03167.19 EGO29256.1 - 2.6e-16 60.0 0.0 5.6e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4171 PF13775.6 EGO29256.1 - 0.076 13.5 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) AsmA PF05170.14 EGO29257.1 - 0.1 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 AsmA family PS_Dcarbxylase PF02666.15 EGO29258.1 - 1.2e-50 171.9 0.0 1.5e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase S4_2 PF13275.6 EGO29258.1 - 0.083 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 S4 domain Asp PF00026.23 EGO29259.1 - 3.5e-80 269.8 3.7 4.4e-80 269.4 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO29259.1 - 1.7e-08 34.9 1.1 0.00019 21.7 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGO29259.1 - 0.00088 19.1 0.0 0.0032 17.3 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGO29259.1 - 0.19 12.4 0.6 3.7 8.2 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease Aldo_ket_red PF00248.21 EGO29260.1 - 3.4e-63 213.6 0.0 4.5e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rad52_Rad22 PF04098.15 EGO29260.1 - 0.013 15.5 0.0 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein NAF PF03822.14 EGO29260.1 - 0.062 13.5 0.0 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 NAF domain Aldo_ket_red PF00248.21 EGO29261.1 - 4.5e-62 209.9 0.0 5.4e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 EGO29261.1 - 0.0023 18.1 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 NAF domain G-alpha PF00503.20 EGO29262.1 - 2.1e-111 372.5 0.0 2.4e-111 372.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO29262.1 - 1.5e-13 50.6 0.2 1.3e-09 37.7 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 EGO29262.1 - 0.012 15.8 0.0 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGO29262.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 EGO29262.1 - 0.045 14.0 0.1 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGO29262.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EGO29262.1 - 0.065 12.6 0.0 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGO29262.1 - 0.08 13.3 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 EGO29262.1 - 0.09 12.3 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO29262.1 - 0.13 12.4 0.0 24 5.0 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase GPP34 PF05719.11 EGO29263.1 - 3.6e-66 223.1 0.3 4.4e-66 222.8 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PDCD2_C PF04194.13 EGO29264.1 - 0.072 13.2 0.9 0.19 11.8 0.9 1.9 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain SSFA2_C PF14723.6 EGO29264.1 - 1.3 8.9 4.7 0.18 11.7 0.6 1.7 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Chs7 PF12271.8 EGO29265.1 - 5.8e-84 281.9 8.6 7.2e-84 281.5 8.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Aldo_ket_red PF00248.21 EGO29266.1 - 1.9e-64 217.7 0.0 2.5e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.31 EGO29267.1 - 3.5e-06 27.2 0.1 6.6e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain Neuraminidase PF18413.1 EGO29269.1 - 0.064 12.9 0.1 0.091 12.4 0.1 1.2 1 0 0 1 1 1 0 Neuraminidase-like domain zf-CCHC PF00098.23 EGO29270.1 - 4.7e-08 32.7 5.9 1e-07 31.7 5.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO29270.1 - 6e-05 23.3 0.1 6e-05 23.3 0.1 2.7 3 1 1 4 4 4 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO29270.1 - 0.0073 16.2 2.0 0.016 15.2 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 EGO29270.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.6 EGO29270.1 - 0.14 11.9 1.2 0.29 10.9 1.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EGO29270.1 - 0.22 11.3 1.9 0.4 10.4 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EGO29271.1 - 0.00032 20.5 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Toprim_C_rpt PF13368.6 EGO29271.1 - 0.099 12.6 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Retrotrans_gag PF03732.17 EGO29272.1 - 1e-06 28.9 0.5 1.8e-06 28.1 0.5 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO29272.1 - 4.3e-05 23.4 2.2 7.3e-05 22.7 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle PKcGMP_CC PF16808.5 EGO29273.1 - 0.059 13.2 0.8 0.11 12.4 0.8 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 EGO29273.1 - 0.068 13.5 1.1 0.11 12.9 0.2 1.7 1 1 1 2 2 2 0 Csm1 N-terminal domain YbaB_DNA_bd PF02575.16 EGO29273.1 - 0.073 13.3 0.3 0.14 12.4 0.2 1.6 1 1 0 1 1 1 0 YbaB/EbfC DNA-binding family Pkinase PF00069.25 EGO29274.1 - 2e-08 33.9 0.0 4.9e-06 26.1 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29274.1 - 0.00096 18.5 0.0 0.0073 15.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase BTB PF00651.31 EGO29275.1 - 0.0051 17.0 0.1 0.0051 17.0 0.1 1.0 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGO29276.1 - 1.4e-05 25.3 0.1 4.4e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain DcpS_C PF11969.8 EGO29278.1 - 2.4e-24 86.0 0.0 3.6e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 EGO29278.1 - 2.4e-18 66.9 0.0 9.8e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 EGO29278.1 - 0.16 12.7 0.8 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 HIT domain Alpha-L-AF_C PF06964.12 EGO29279.1 - 4.6e-36 124.5 1.0 1.3e-35 123.0 0.3 2.0 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_6 PF03422.15 EGO29279.1 - 0.0026 18.1 4.5 0.0094 16.3 2.9 2.4 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) CBM_4_9 PF02018.17 EGO29279.1 - 0.81 9.9 5.9 0.25 11.6 1.7 2.3 2 1 0 2 2 2 0 Carbohydrate binding domain D-ser_dehydrat PF14031.6 EGO29281.1 - 6.6e-26 90.8 0.0 6.3e-25 87.7 0.0 2.5 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGO29281.1 - 9e-12 45.1 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain AAA_28 PF13521.6 EGO29282.1 - 2.9e-23 82.9 0.0 3.8e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO29282.1 - 1.6e-07 31.9 0.1 2.9e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO29282.1 - 0.00017 22.0 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EGO29282.1 - 0.0004 20.8 0.1 0.00073 20.0 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO29282.1 - 0.0011 19.2 0.1 0.0018 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGO29282.1 - 0.0025 17.9 0.1 0.0043 17.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGO29282.1 - 0.004 16.9 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGO29282.1 - 0.0064 16.5 0.1 0.01 15.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 EGO29282.1 - 0.0076 16.0 0.1 0.0099 15.6 0.1 1.6 1 1 0 1 1 1 1 Cytidylate kinase AAA_22 PF13401.6 EGO29282.1 - 0.0088 16.3 0.3 0.029 14.6 0.3 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO29282.1 - 0.022 14.7 0.1 0.12 12.2 0.1 2.2 2 1 1 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 EGO29282.1 - 0.024 15.1 0.4 0.048 14.2 0.4 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EGO29282.1 - 0.029 14.1 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGO29282.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin TIP49 PF06068.13 EGO29282.1 - 0.034 13.3 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 EGO29282.1 - 0.038 13.0 0.1 0.058 12.4 0.1 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EGO29282.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 EGO29282.1 - 0.045 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 EGO29282.1 - 0.046 14.2 0.3 0.12 12.8 0.1 1.8 2 1 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 EGO29282.1 - 0.046 13.6 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 EGO29282.1 - 0.049 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 EGO29282.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Methyltransf_16 PF10294.9 EGO29283.1 - 1.1e-10 41.5 0.1 9.5e-08 32.0 0.1 2.4 1 1 0 1 1 1 1 Lysine methyltransferase Fungal_lectin PF07938.12 EGO29284.1 - 3.7e-15 56.1 0.1 1.2e-13 51.1 0.0 2.0 1 1 1 2 2 2 2 Fungal fucose-specific lectin Metallophos_2 PF12850.7 EGO29285.1 - 1.1e-19 71.2 0.1 1.5e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGO29285.1 - 1.1e-06 29.3 1.3 0.029 14.9 0.2 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase UPF0203 PF05254.12 EGO29286.1 - 5.2e-27 93.9 1.7 6.4e-27 93.6 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EGO29286.1 - 0.0032 17.6 4.1 0.97 9.7 0.2 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 EGO29286.1 - 0.086 13.1 0.9 4.6 7.6 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Ribosomal_L33 PF00471.20 EGO29287.1 - 6.3e-08 32.9 0.0 8.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 EGO29287.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Ank_2 PF12796.7 EGO29288.1 - 0.0052 17.4 0.0 0.007 16.9 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO29288.1 - 0.015 15.7 0.0 0.55 10.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 EGO29288.1 - 0.037 14.3 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO29288.1 - 0.076 13.6 0.0 0.22 12.1 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Hist_deacetyl PF00850.19 EGO29289.1 - 2.3e-61 208.0 0.0 4.5e-61 207.0 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain TMEM51 PF15345.6 EGO29291.1 - 0.00066 19.6 0.1 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 Transmembrane protein 51 PMP1_2 PF08114.11 EGO29291.1 - 0.0024 17.6 0.4 0.0041 16.8 0.4 1.3 1 0 0 1 1 1 1 ATPase proteolipid family OppC_N PF12911.7 EGO29291.1 - 0.066 13.2 1.2 0.21 11.6 1.2 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Herpes_gE PF02480.16 EGO29291.1 - 0.19 10.4 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Alpha_adaptinC2 PF02883.20 EGO29293.1 - 0.057 13.7 0.1 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Adaptin C-terminal domain GLYCAM-1 PF05242.11 EGO29293.1 - 0.11 12.7 0.2 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Robl_LC7 PF03259.17 EGO29294.1 - 1.7e-07 30.9 0.0 4.6e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Roadblock/LC7 domain DUF4922 PF16269.5 EGO29295.1 - 0.014 15.1 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) PDDEXK_1 PF12705.7 EGO29298.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DivIC PF04977.15 EGO29298.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 EGO29298.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) APG6_N PF17675.1 EGO29299.1 - 0.024 15.1 0.3 0.043 14.3 0.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region THOC7 PF05615.13 EGO29299.1 - 0.073 13.4 1.4 3.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 DUF5363 PF17320.2 EGO29299.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5363) DUF2829 PF11195.8 EGO29299.1 - 0.13 12.5 0.1 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) GRIP PF01465.20 EGO29300.1 - 1.6e-16 59.9 0.6 5e-16 58.3 0.3 2.1 2 0 0 2 2 2 1 GRIP domain DUF5416 PF17437.2 EGO29300.1 - 0.0063 16.3 0.7 0.013 15.3 0.7 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5416) Pentapeptide_4 PF13599.6 EGO29300.1 - 0.19 12.0 1.2 0.4 10.9 1.2 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Nup54_57_C PF18570.1 EGO29300.1 - 0.22 11.1 0.1 0.22 11.1 0.1 3.0 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain DUF4407 PF14362.6 EGO29300.1 - 4.2 6.6 42.3 0.67 9.3 18.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Kelch_4 PF13418.6 EGO29301.1 - 9.7e-28 95.9 10.5 1.1e-05 25.4 0.1 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGO29301.1 - 2.7e-26 91.3 5.2 5.6e-06 26.5 0.1 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.6 EGO29301.1 - 1.5e-17 63.5 0.0 4.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 EGO29301.1 - 6.9e-16 57.9 7.4 6.6e-05 23.1 0.3 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EGO29301.1 - 1.9e-15 56.4 10.9 3.6e-05 23.6 0.1 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGO29301.1 - 7.6e-15 54.2 6.4 0.00018 21.0 0.0 5.2 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EGO29301.1 - 6.8e-14 51.2 6.2 0.0001 22.1 0.2 4.7 4 0 0 4 4 4 3 Kelch motif RXT2_N PF08595.11 EGO29301.1 - 0.86 9.6 7.8 1.8 8.6 3.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EGO29301.1 - 1 9.8 17.3 4.9 7.6 8.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EGO29301.1 - 6.3 6.0 15.8 0.66 9.2 9.7 2.1 2 0 0 2 2 2 0 NOA36 protein Sporozoite_P67 PF05642.11 EGO29301.1 - 7.1 4.6 7.2 13 3.8 7.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 EGO29301.1 - 7.6 6.2 11.9 2.8 7.6 4.8 2.3 2 0 0 2 2 2 0 FAM176 family Asp PF00026.23 EGO29302.1 - 2.9e-61 207.6 0.5 4e-61 207.2 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO29302.1 - 3.8e-09 37.0 8.5 1.1e-08 35.5 0.2 2.9 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO29302.1 - 0.0096 16.6 0.5 0.16 12.7 0.2 3.0 2 1 0 2 2 2 1 Aspartyl protease KRE1 PF17056.5 EGO29302.1 - 0.026 14.3 3.1 0.3 10.8 1.8 2.6 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 F-box-like PF12937.7 EGO29304.1 - 9.3e-09 35.1 0.8 3.3e-08 33.3 0.8 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO29304.1 - 0.1 12.5 0.2 0.42 10.6 0.2 2.0 1 0 0 1 1 1 0 F-box domain Atg14 PF10186.9 EGO29305.1 - 6.8e-50 170.0 0.0 1.6e-49 168.7 0.0 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 EGO29305.1 - 0.14 10.3 0.7 0.18 9.9 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ADH_N PF08240.12 EGO29306.1 - 1.9e-29 101.7 0.7 3.5e-29 100.9 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO29306.1 - 2.1e-10 40.6 0.3 7.6e-10 38.9 0.1 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EGO29306.1 - 4.2e-06 26.6 0.3 1.1e-05 25.2 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 EGO29306.1 - 4e-05 23.2 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EGO29306.1 - 0.0024 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EGO29306.1 - 0.0046 15.7 0.2 0.015 14.0 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGO29306.1 - 0.072 12.3 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Ribosomal_L14e PF01929.17 EGO29308.1 - 2.7e-31 107.9 0.4 5.2e-31 107.0 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EGO29308.1 - 1.2e-06 28.2 0.7 2.3e-06 27.3 0.2 1.7 2 0 0 2 2 2 1 KOW motif MARCKS PF02063.17 EGO29310.1 - 0.2 11.6 0.0 0.22 11.4 0.0 1.0 1 0 0 1 1 1 0 MARCKS family F-box-like PF12937.7 EGO29313.1 - 0.032 14.1 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 EGO29313.1 - 0.064 13.7 4.5 2.5 8.7 0.2 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGO29315.1 - 0.0046 16.8 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like RNA_lig_T4_1 PF09511.10 EGO29316.1 - 3.2e-83 278.9 0.0 5.2e-83 278.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EGO29316.1 - 7e-29 101.1 0.0 1.2e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EGO29316.1 - 1.9e-22 79.9 0.0 3.4e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 EGO29316.1 - 0.014 15.9 0.0 0.035 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NHL PF01436.21 EGO29316.1 - 0.2 11.7 0.2 0.48 10.6 0.2 1.6 1 0 0 1 1 1 0 NHL repeat Exo70 PF03081.15 EGO29318.1 - 5.3e-34 117.9 0.0 7.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CBFD_NFYB_HMF PF00808.23 EGO29319.1 - 1.1e-26 92.9 0.2 1.6e-26 92.3 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO29319.1 - 9.2e-05 22.8 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EGO29319.1 - 0.0044 17.0 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 EGO29319.1 - 0.0065 16.6 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAN_3 PF08277.12 EGO29319.1 - 0.031 14.1 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 PAN-like domain ANAPC4_WD40 PF12894.7 EGO29320.1 - 0.02 15.2 0.0 1.2 9.5 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO29320.1 - 0.027 15.3 0.0 0.93 10.5 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat MFS_1 PF07690.16 EGO29322.1 - 1.5e-40 139.3 45.1 1.5e-40 139.3 45.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DSPc PF00782.20 EGO29323.1 - 9.3e-44 148.5 0.0 7.4e-29 100.2 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGO29323.1 - 3.4e-05 24.1 0.6 0.0081 16.4 0.1 2.5 2 0 0 2 2 2 2 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGO29323.1 - 0.01 15.4 1.0 0.01 15.4 1.0 1.6 2 1 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO29323.1 - 0.045 13.9 0.2 0.086 13.0 0.2 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPn PF14671.6 EGO29323.1 - 0.053 14.0 0.1 1.9 8.9 0.0 2.6 3 0 0 3 3 3 0 Dual specificity protein phosphatase, N-terminal half ANTAR PF03861.14 EGO29323.1 - 0.093 12.6 0.0 7.2 6.5 0.0 2.8 3 0 0 3 3 3 0 ANTAR domain SET PF00856.28 EGO29325.1 - 1e-09 39.0 5.3 4.1e-09 37.0 5.3 2.0 1 1 0 1 1 1 1 SET domain PPV_E1_N PF00524.18 EGO29325.1 - 0.011 16.2 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 E1 Protein, N terminal domain DcuC PF03606.15 EGO29326.1 - 0.33 9.3 0.0 0.42 9.0 0.0 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Pkinase_fungal PF17667.1 EGO29327.1 - 3.1e-19 69.0 0.2 1.4e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase BIR PF00653.21 EGO29329.1 - 1.7e-32 111.9 2.9 3.7e-16 59.5 1.2 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 EGO29329.1 - 0.0099 15.9 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C3HC PF07967.13 EGO29329.1 - 0.097 12.7 1.9 2.9 7.9 0.0 2.7 2 1 1 3 3 3 0 C3HC zinc finger-like Lactamase_B_2 PF12706.7 EGO29330.1 - 5.9e-13 48.8 2.1 7.5e-12 45.2 2.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGO29330.1 - 2.9e-10 39.7 0.1 1.6e-09 37.3 0.1 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 EGO29330.1 - 0.00085 19.4 2.4 0.002 18.2 0.9 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily FA_desaturase PF00487.24 EGO29331.1 - 1.6e-26 93.7 12.5 2.7e-26 93.0 12.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGO29331.1 - 1.9e-08 34.6 0.1 3.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF4784 PF16023.5 EGO29333.1 - 0.08 11.9 0.1 0.62 8.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4784) GMC_oxred_N PF00732.19 EGO29334.1 - 2.2e-52 178.3 0.0 3e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO29334.1 - 4.1e-21 76.0 0.2 2e-13 51.1 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 EGO29334.1 - 1.9e-06 27.7 0.0 0.0002 21.1 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO29334.1 - 2.8e-06 26.7 0.3 0.00017 20.8 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGO29334.1 - 3.6e-05 23.9 0.8 0.00017 21.8 0.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGO29334.1 - 9.9e-05 21.5 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EGO29334.1 - 0.0015 17.3 0.1 0.0028 16.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGO29334.1 - 0.0088 15.3 0.4 0.063 12.5 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO29334.1 - 0.0094 15.2 0.1 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EGO29334.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MutS_V PF00488.21 EGO29335.1 - 1.3e-83 279.7 0.1 2.1e-83 279.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO29335.1 - 1.2e-35 123.5 1.5 1.6e-35 123.0 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGO29335.1 - 2.4e-17 63.0 0.7 6.6e-17 61.6 0.7 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGO29335.1 - 7.5e-17 61.9 1.5 6.5e-16 58.8 0.0 3.1 4 0 0 4 4 4 1 MutS domain II AAA_27 PF13514.6 EGO29335.1 - 0.085 12.4 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Methyltr_RsmB-F PF01189.17 EGO29336.1 - 1.5e-38 132.5 0.0 5.1e-37 127.5 0.0 2.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF2431 PF10354.9 EGO29336.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltr_RsmF_N PF17125.5 EGO29336.1 - 0.029 14.9 0.0 0.063 13.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EGO29336.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.8 2 1 0 2 2 2 0 FtsJ-like methyltransferase MFS_1 PF07690.16 EGO29337.1 - 6.7e-23 81.2 43.9 1e-22 80.6 43.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SAP18 PF06487.12 EGO29338.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Pmp3 PF01679.17 EGO29339.1 - 3.9e-15 55.8 4.0 4.3e-15 55.7 4.0 1.2 1 1 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 EGO29339.1 - 0.13 12.3 0.4 0.19 11.8 0.4 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF5534 PF17686.1 EGO29339.1 - 0.17 12.2 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5534) G-alpha PF00503.20 EGO29340.1 - 3.8e-100 335.5 0.0 5e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO29340.1 - 1.7e-09 37.3 0.0 0.00024 20.6 0.0 3.0 3 0 0 3 3 3 2 ADP-ribosylation factor family MCM PF00493.23 EGO29340.1 - 0.0056 15.8 0.1 0.045 12.8 0.0 2.3 3 0 0 3 3 3 1 MCM P-loop domain AAA_29 PF13555.6 EGO29340.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 EGO29340.1 - 0.017 14.5 0.0 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Roc PF08477.13 EGO29340.1 - 0.031 14.5 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGO29340.1 - 0.044 13.6 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGO29340.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EGO29340.1 - 0.087 12.4 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Ras family La PF05383.17 EGO29342.1 - 1.7e-07 31.2 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 La domain DUF4611 PF15387.6 EGO29342.1 - 0.33 11.2 4.0 0.28 11.4 2.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4632 PF15451.6 EGO29342.1 - 2.9 8.0 4.5 7 6.8 4.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4632) Abhydrolase_3 PF07859.13 EGO29344.1 - 9.3e-64 215.2 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGO29344.1 - 7.1e-07 28.5 0.1 2.3e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EGO29344.1 - 1.5e-06 27.4 0.0 1.9e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGO29344.1 - 0.0011 18.4 0.0 0.0088 15.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EGO29344.1 - 0.0074 15.2 0.0 0.014 14.4 0.0 1.3 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EGO29344.1 - 0.039 13.6 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AdoHcyase PF05221.17 EGO29346.1 - 5.7e-133 442.7 0.0 2.1e-72 243.8 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGO29346.1 - 1.3e-84 282.1 1.3 1.9e-84 281.6 1.3 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGO29346.1 - 3.9e-09 36.1 0.0 8.9e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGO29346.1 - 0.00019 21.1 0.1 0.00029 20.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGO29346.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Mitochondr_Som1 PF11093.8 EGO29347.1 - 6.6e-09 35.6 0.2 7.9e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Pox_A_type_inc PF04508.12 EGO29350.1 - 0.012 15.4 8.8 0.22 11.5 1.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MAD PF05557.13 EGO29350.1 - 0.88 7.9 5.7 2.1 6.6 2.5 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein GST_N PF02798.20 EGO29351.1 - 1.7e-16 60.3 0.0 3.8e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO29351.1 - 1e-11 45.1 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO29351.1 - 3.7e-07 30.4 0.0 7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO29351.1 - 6e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO29351.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGO29351.1 - 0.051 14.3 0.0 0.21 12.3 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C PF00043.25 EGO29351.1 - 0.068 13.4 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ssu72 PF04722.13 EGO29352.1 - 0.033 13.7 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Ssu72-like protein DUF1627 PF07789.12 EGO29352.1 - 0.46 10.1 1.8 3.9 7.1 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1627) IBR PF01485.21 EGO29353.1 - 1.5e-16 60.4 33.8 9.7e-09 35.3 6.2 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGO29353.1 - 1.6e-05 24.8 4.6 1.6e-05 24.8 4.6 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO29353.1 - 8.6e-05 22.3 4.1 8.6e-05 22.3 4.1 4.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO29353.1 - 0.00015 21.8 4.4 0.00015 21.8 4.4 5.0 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGO29353.1 - 0.0018 18.1 4.1 0.0018 18.1 4.1 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO29353.1 - 0.0066 16.3 3.2 0.0066 16.3 3.2 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO29353.1 - 0.014 15.7 4.2 0.014 15.7 4.2 4.2 2 1 1 3 3 3 0 Ring finger domain zf-C2H2_6 PF13912.6 EGO29353.1 - 0.016 15.2 0.2 0.016 15.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_5 PF14634.6 EGO29353.1 - 0.017 15.1 5.1 0.017 15.1 5.1 4.3 3 2 1 4 4 4 0 zinc-RING finger domain RRM_1 PF00076.22 EGO29353.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPD52 PF04201.15 EGO29354.1 - 0.039 13.6 0.6 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Tumour protein D52 family NuA4 PF09340.10 EGO29354.1 - 0.062 13.2 0.3 0.2 11.6 0.3 1.9 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 ATP19 PF11022.8 EGO29355.1 - 6.5e-23 80.9 0.5 7.3e-23 80.7 0.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit K DUF2034 PF10356.9 EGO29356.1 - 2.8e-18 66.0 0.3 3.9e-16 59.0 0.3 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EGO29356.1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease Glyco_hydro_16 PF00722.21 EGO29357.1 - 0.00029 20.4 0.7 0.00048 19.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Clp1 PF06807.14 EGO29358.1 - 0.0023 18.3 0.0 0.0025 18.2 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 RNA_pol_Rpb2_3 PF04565.16 EGO29358.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 BicD PF09730.9 EGO29360.1 - 4.7e-05 22.0 4.1 5.3e-05 21.9 4.1 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D GAS PF13851.6 EGO29360.1 - 0.00012 21.5 3.1 0.00015 21.2 3.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EGO29360.1 - 0.00045 20.7 4.9 0.00048 20.7 4.2 1.4 1 1 0 1 1 1 1 Apg6 coiled-coil region FliD_N PF02465.18 EGO29360.1 - 0.018 15.7 1.8 0.085 13.6 1.8 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CCDC85 PF10226.9 EGO29360.1 - 0.021 14.5 0.1 0.021 14.5 0.1 1.9 1 1 1 2 2 2 0 CCDC85 family Nup88 PF10168.9 EGO29360.1 - 0.025 12.4 4.3 0.027 12.3 4.3 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF4201 PF13870.6 EGO29360.1 - 0.027 14.2 3.0 0.034 13.9 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 EGO29360.1 - 0.028 14.5 4.5 0.088 12.8 4.5 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IL7 PF01415.16 EGO29360.1 - 0.065 13.3 0.3 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Interleukin 7/9 family JIP_LZII PF16471.5 EGO29360.1 - 0.091 12.9 2.1 3.2 8.0 0.1 2.9 1 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 EGO29360.1 - 0.1 11.5 6.0 0.13 11.2 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 EGO29360.1 - 0.1 13.0 3.8 0.18 12.2 3.4 1.7 1 1 1 2 2 2 0 Snapin/Pallidin CLZ PF16526.5 EGO29360.1 - 0.11 12.9 2.7 7.9 6.9 0.1 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 EGO29360.1 - 0.19 10.2 4.1 0.2 10.2 4.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 EGO29360.1 - 0.26 12.0 1.9 1.5 9.5 0.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FOXP-CC PF16159.5 EGO29360.1 - 0.39 11.4 2.2 2.4 8.8 1.0 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain ZapB PF06005.12 EGO29360.1 - 0.82 10.2 6.8 4.6 7.7 0.1 2.3 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 EGO29360.1 - 1.4 9.6 8.8 0.8 10.4 4.4 2.5 2 1 1 3 3 3 0 SlyX MEIOC PF15189.6 EGO29360.1 - 1.7 8.3 7.1 3.3 7.3 1.4 2.4 1 1 1 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC Fib_alpha PF08702.10 EGO29360.1 - 4.2 7.6 6.9 12 6.0 1.4 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EGO29360.1 - 5.8 6.7 8.1 8.2 6.3 0.1 2.5 2 1 1 3 3 3 0 Septum formation initiator Mito_carr PF00153.27 EGO29361.1 - 3.2e-60 200.1 2.2 1.3e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRF PF01765.19 EGO29362.1 - 1.7e-28 99.6 5.4 1.7e-28 99.6 5.4 1.6 1 1 1 2 2 2 1 Ribosome recycling factor CHIP_TPR_N PF18391.1 EGO29362.1 - 0.29 11.9 3.6 0.19 12.5 1.0 1.9 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Uso1_p115_C PF04871.13 EGO29362.1 - 3 8.2 7.7 1 9.8 0.3 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SNF2_N PF00176.23 EGO29363.1 - 1.3e-54 185.2 1.1 2.3e-54 184.5 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO29363.1 - 3.3e-12 46.7 0.0 4.2e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EGO29363.1 - 6.4e-10 38.9 4.8 1.7e-09 37.5 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO29363.1 - 3.3e-09 36.4 4.3 3.3e-09 36.4 4.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO29363.1 - 2e-08 34.0 7.0 4.7e-08 32.8 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO29363.1 - 2.9e-08 33.4 5.5 8.7e-08 31.9 5.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO29363.1 - 1.4e-06 28.5 6.6 3.2e-06 27.4 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO29363.1 - 3.3e-06 26.9 4.9 6.7e-06 26.0 4.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGO29363.1 - 2.8e-05 24.2 6.7 7.4e-05 22.8 6.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 EGO29363.1 - 0.00012 22.1 0.0 0.00035 20.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 EGO29363.1 - 0.014 15.2 9.3 0.013 15.3 6.6 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 AAA_34 PF13872.6 EGO29363.1 - 0.029 13.3 0.0 0.076 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_11 PF17123.5 EGO29363.1 - 0.043 13.6 5.5 0.11 12.3 5.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger DUF4196 PF13846.6 EGO29363.1 - 0.15 12.2 15.7 0.3 11.3 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4196) zf-RING_4 PF14570.6 EGO29363.1 - 0.31 10.9 6.0 0.87 9.4 6.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EGO29363.1 - 1.8 8.6 4.2 4.9 7.3 4.2 1.8 1 0 0 1 1 1 0 Double zinc ribbon ABC_membrane_2 PF06472.15 EGO29364.1 - 8.8e-78 261.4 0.1 1.5e-77 260.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGO29364.1 - 3.8e-15 56.6 0.0 6.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGO29364.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGO29364.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGO29364.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Peptidase_M20 PF01546.28 EGO29366.1 - 6.9e-28 97.8 0.0 1.2e-27 97.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO29366.1 - 3.2e-10 39.9 0.0 7.3e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO29366.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M28 LRR_4 PF12799.7 EGO29367.1 - 1.2e-09 38.3 2.7 0.67 10.5 0.0 6.7 6 2 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGO29367.1 - 1.5e-06 27.8 3.7 25 5.3 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 EGO29367.1 - 5.8e-05 22.8 0.0 4.2 7.2 0.0 5.3 4 2 2 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 EGO29367.1 - 0.013 15.9 0.9 1.1e+02 4.0 0.0 6.1 6 2 0 6 6 6 0 Leucine Rich Repeat STE3 PF02076.15 EGO29368.1 - 2.9e-94 315.5 17.4 3.5e-94 315.3 17.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_M20 PF01546.28 EGO29371.1 - 8.8e-26 90.9 0.0 1.4e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO29371.1 - 4.2e-10 39.5 0.0 7.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-ISL3 PF14690.6 EGO29375.1 - 0.052 14.2 0.0 0.063 13.9 0.0 1.2 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2415 PF10313.9 EGO29376.1 - 0.13 12.2 0.1 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Lectin_C_term PF18022.1 EGO29378.1 - 4.7e-45 152.2 0.3 9e-45 151.3 0.3 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain Agglutinin_C PF18021.1 EGO29378.1 - 8.8e-24 83.8 0.2 1.4e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 Agglutinin C-terminal RicinB_lectin_2 PF14200.6 EGO29378.1 - 2.4e-20 73.1 5.3 8.1e-17 61.7 0.2 3.4 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ank PF00023.30 EGO29380.1 - 3.2e-08 33.7 0.0 0.0034 17.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGO29380.1 - 1.8e-07 31.7 0.1 1.8e-05 25.3 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO29380.1 - 2e-05 24.6 0.1 0.95 10.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGO29380.1 - 0.00096 19.7 0.1 0.13 12.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO29380.1 - 0.048 14.0 0.1 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) G-alpha PF00503.20 EGO29383.1 - 1.6e-123 412.4 0.0 1.9e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO29383.1 - 2.4e-10 40.1 0.1 2.4e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 EGO29383.1 - 0.00095 19.4 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGO29383.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 EGO29383.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO29383.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO29383.1 - 0.081 13.2 0.1 0.44 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain ODR4-like PF14778.6 EGO29383.1 - 0.096 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like Zeta_toxin PF06414.12 EGO29383.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FA_desaturase PF00487.24 EGO29385.1 - 2.1e-16 60.5 24.0 3.2e-16 59.9 24.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGO29385.1 - 9.1e-12 45.0 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MOR2-PAG1_N PF14222.6 EGO29387.1 - 1.1e-170 569.3 0.0 1.7e-169 565.4 0.0 2.2 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EGO29387.1 - 3e-83 279.6 2.6 3e-83 279.6 2.6 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGO29387.1 - 1.2e-20 72.9 0.6 3.4e-11 41.6 0.1 3.1 3 0 0 3 3 3 3 Cell morphogenesis central region Mlh1_C PF16413.5 EGO29388.1 - 5.2e-91 304.7 0.0 1.3e-90 303.4 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGO29388.1 - 1.4e-28 99.0 0.1 2.9e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGO29388.1 - 9e-13 48.2 0.0 2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGO29388.1 - 3.3e-07 30.8 0.0 7.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBS PF00571.28 EGO29389.1 - 4.2e-07 30.3 0.0 0.0028 18.1 0.0 2.2 2 0 0 2 2 2 2 CBS domain MRC1 PF09444.10 EGO29391.1 - 0.15 12.6 4.4 0.39 11.2 4.4 1.6 1 0 0 1 1 1 0 MRC1-like domain RPN1_RPN2_N PF17781.1 EGO29392.1 - 1.7e-108 362.7 0.0 2.8e-108 362.0 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGO29392.1 - 6.1e-30 103.0 0.1 2.5e-29 101.1 0.1 2.0 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGO29392.1 - 9.6e-22 76.3 20.6 0.00034 20.9 0.2 8.6 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGO29392.1 - 5.4e-05 23.5 4.0 0.091 13.2 0.1 4.9 6 2 1 7 7 7 2 HEAT repeats Cyclin_N PF00134.23 EGO29393.1 - 1.2e-45 154.3 2.1 2.5e-45 153.3 0.7 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO29393.1 - 1.1e-26 93.2 0.2 4.8e-26 91.2 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain AAA_22 PF13401.6 EGO29394.1 - 0.00024 21.4 0.0 0.00059 20.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGO29394.1 - 0.00025 21.0 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO29394.1 - 0.0027 18.1 0.0 0.0046 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EGO29394.1 - 0.0061 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EGO29394.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ELYS PF13934.6 EGO29394.1 - 0.043 13.8 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex assembly RNA_helicase PF00910.22 EGO29394.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EGO29394.1 - 0.091 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cwf_Cwc_15 PF04889.12 EGO29396.1 - 0.028 14.2 4.4 0.055 13.2 4.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S10 PF00450.22 EGO29397.1 - 4.3e-115 385.5 0.0 5.6e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyoxalase PF00903.25 EGO29398.1 - 0.00032 20.9 0.1 0.0076 16.4 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGO29398.1 - 0.098 12.6 0.1 0.12 12.3 0.1 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain DAO PF01266.24 EGO29399.1 - 5.7e-29 101.8 2.9 8.2e-29 101.3 2.9 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO29399.1 - 0.0019 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO29399.1 - 0.0059 15.9 0.1 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGO29399.1 - 0.01 16.3 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 EGO29399.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EGO29399.1 - 0.07 13.4 1.4 0.35 11.1 0.4 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 EGO29399.1 - 0.21 11.0 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FA_desaturase PF00487.24 EGO29402.1 - 2.5e-23 83.3 15.6 2.5e-23 83.3 15.6 1.7 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 EGO29402.1 - 1e-18 66.5 0.5 1.6e-18 65.8 0.5 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Polysacc_synt_C PF14667.6 EGO29402.1 - 0.74 9.9 7.9 0.5 10.4 1.3 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Acetyltransf_3 PF13302.7 EGO29403.1 - 2.4e-07 31.5 0.0 4.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO29403.1 - 3e-05 24.2 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO29403.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO29403.1 - 0.028 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein HEAT PF02985.22 EGO29405.1 - 0.00014 21.8 0.3 18 5.9 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGO29405.1 - 0.00015 22.0 6.5 0.75 10.2 0.1 5.7 4 2 1 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EGO29405.1 - 0.0008 19.5 14.2 0.073 13.1 0.0 5.4 4 3 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Arg_tRNA_synt_N PF03485.16 EGO29405.1 - 0.074 13.6 0.0 2.1 9.0 0.0 2.9 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain Rod_cone_degen PF15201.6 EGO29405.1 - 0.93 9.6 2.6 2.5 8.3 1.7 2.2 2 0 0 2 2 2 0 Progressive rod-cone degeneration NARP1 PF12569.8 EGO29406.1 - 3.1e-152 508.1 3.7 1.4e-150 502.7 0.5 2.6 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EGO29406.1 - 2e-14 52.4 8.0 0.0089 16.1 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO29406.1 - 1.8e-11 43.9 4.2 1.4 9.9 0.0 8.9 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO29406.1 - 1e-10 42.0 10.0 0.36 11.4 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO29406.1 - 4.3e-10 40.1 6.8 0.73 10.5 0.0 7.7 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO29406.1 - 6.1e-08 32.2 6.8 0.0061 16.2 0.1 5.7 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 EGO29406.1 - 2.2e-06 27.4 8.4 0.0098 16.0 0.1 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO29406.1 - 6.2e-05 22.6 9.1 0.0059 16.4 0.2 6.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO29406.1 - 0.00012 21.8 0.2 2 8.6 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO29406.1 - 0.00017 21.8 6.2 0.67 10.3 0.0 6.0 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO29406.1 - 0.0011 19.1 0.0 0.57 10.7 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO29406.1 - 0.0053 16.9 2.1 31 4.8 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO29406.1 - 0.047 13.9 10.1 0.32 11.3 0.0 5.2 6 2 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGO29406.1 - 0.062 12.7 0.1 0.57 9.5 0.0 2.6 3 1 1 4 4 4 0 MalT-like TPR region PhoQ_Sensor PF08918.10 EGO29406.1 - 0.13 12.1 0.4 2.5 7.9 0.0 2.6 2 1 1 3 3 3 0 PhoQ Sensor TPR_4 PF07721.14 EGO29406.1 - 0.14 12.9 1.7 1.3e+02 3.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGO29406.1 - 1.9 8.6 6.8 0.62 10.2 0.1 3.5 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGO29406.1 - 2.2 9.1 5.4 2.5e+02 2.7 0.0 5.7 8 0 0 8 8 5 0 Tetratricopeptide repeat Rnk_N PF14760.6 EGO29407.1 - 0.046 14.2 0.1 0.087 13.3 0.1 1.4 1 0 0 1 1 1 0 Rnk N-terminus Exog_C PF18026.1 EGO29407.1 - 0.27 11.3 0.4 1.8 8.7 0.1 2.1 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Cwf_Cwc_15 PF04889.12 EGO29408.1 - 0.00059 19.6 0.5 0.00077 19.3 0.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGO29408.1 - 0.76 7.8 3.3 0.91 7.5 3.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hydrophobin PF01185.18 EGO29409.1 - 8.5e-17 61.6 12.2 1.1e-16 61.2 12.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Stn1 PF10451.9 EGO29410.1 - 3.9e-07 29.3 0.1 1.4e-06 27.5 0.0 1.9 3 0 0 3 3 3 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EGO29410.1 - 0.017 15.1 0.6 0.25 11.4 0.6 2.4 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain HMG-CoA_red PF00368.18 EGO29411.1 - 7.4e-143 476.0 5.8 9.9e-143 475.6 5.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EGO29411.1 - 4.6e-18 65.5 0.4 1.2e-17 64.1 0.4 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGO29411.1 - 1.2e-07 30.3 0.0 1.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Patched family Herpes_LMP1 PF05297.11 EGO29411.1 - 1.7 7.7 5.8 2.7 7.1 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) 3Beta_HSD PF01073.19 EGO29414.1 - 3.6e-27 95.1 0.0 4e-17 62.1 0.0 2.6 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO29414.1 - 9.4e-11 41.4 0.0 3.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 EGO29414.1 - 7.5e-10 38.7 0.0 3.8e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO29414.1 - 0.00042 19.5 0.1 0.0021 17.2 0.1 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGO29414.1 - 0.00052 20.0 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO29414.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO29414.1 - 0.004 17.1 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGO29414.1 - 0.029 14.6 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Aldo_ket_red PF00248.21 EGO29415.1 - 4.1e-47 160.8 0.0 4.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EspF PF04806.12 EGO29415.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 EspF protein repeat ADH_N PF08240.12 EGO29416.1 - 1.3e-28 99.0 1.7 3.1e-28 97.8 1.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO29416.1 - 4.1e-14 52.7 0.0 8.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO29416.1 - 2.1e-13 50.3 0.1 3e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGO29416.1 - 1.6e-07 32.5 0.0 2.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EGO29416.1 - 0.00012 21.5 0.7 0.00017 21.0 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 EGO29416.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EGO29416.1 - 0.022 14.0 0.2 0.19 10.9 0.3 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO29416.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EGO29416.1 - 0.025 15.0 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGO29416.1 - 0.04 14.0 0.4 0.11 12.6 0.4 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Staph_opine_DH PF10100.9 EGO29416.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase HI0933_like PF03486.14 EGO29416.1 - 0.14 10.8 1.1 0.19 10.4 1.1 1.1 1 0 0 1 1 1 0 HI0933-like protein NUDIX PF00293.28 EGO29417.1 - 5.3e-09 36.2 0.0 8.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EGO29417.1 - 2.9e-06 27.2 0.0 6.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) AMP_N PF05195.16 EGO29417.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Radical_SAM PF04055.21 EGO29419.1 - 6.6e-10 39.6 0.0 7.6e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Radical SAM superfamily Alba PF01918.21 EGO29419.1 - 0.013 15.3 0.2 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Alba Fer4_12 PF13353.6 EGO29419.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain NAD_binding_4 PF07993.12 EGO29420.1 - 3.8e-67 226.2 0.0 7.3e-67 225.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGO29420.1 - 1e-65 222.0 0.0 1.4e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGO29420.1 - 2.7e-13 50.1 0.2 1.4e-12 47.8 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 EGO29420.1 - 7.1e-10 38.2 0.0 3.6e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 EGO29420.1 - 2.1e-06 27.4 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO29420.1 - 0.00021 20.4 0.0 0.0006 18.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EGO29420.1 - 0.0003 21.7 0.0 0.001 20.0 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NmrA PF05368.13 EGO29420.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DDE_3 PF13358.6 EGO29421.1 - 7.1e-06 25.8 0.1 0.075 12.8 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease Plavaka PF18759.1 EGO29424.1 - 7.9e-44 150.2 0.1 1.5e-43 149.3 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase Smg4_UPF3 PF03467.15 EGO29424.1 - 0.19 11.7 5.9 0.34 10.9 5.9 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family DUF1848 PF08902.11 EGO29425.1 - 0.21 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Calpain_u2 PF16648.5 EGO29426.1 - 0.096 13.2 0.5 0.096 13.2 0.5 2.2 2 0 0 2 2 2 0 Unstructured region on Calpain-3 Mito_carr PF00153.27 EGO29427.1 - 1.6e-57 191.4 0.1 2.9e-22 78.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 EGO29428.1 - 2.3e-32 111.1 2.7 3.9e-32 110.4 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO29428.1 - 1.6e-16 60.5 0.0 3e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO29428.1 - 7e-12 45.3 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGO29428.1 - 7.1e-07 30.3 0.0 1.3e-06 29.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EGO29428.1 - 0.00047 19.5 1.0 0.00066 19.0 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 EGO29428.1 - 0.026 13.2 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase Shikimate_DH PF01488.20 EGO29428.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGO29428.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding His_Phos_2 PF00328.22 EGO29429.1 - 6.4e-21 75.1 0.0 1.2e-20 74.3 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AMP-binding PF00501.28 EGO29430.1 - 3.3e-90 302.7 0.0 4.6e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO29430.1 - 3.9e-14 53.4 0.3 8.5e-14 52.3 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EGO29430.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cyt-b5 PF00173.28 EGO29431.1 - 4.1e-20 71.7 0.1 8.6e-20 70.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGO29431.1 - 1.3e-12 48.2 18.9 1.3e-12 48.2 18.9 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sec5 PF15469.6 EGO29432.1 - 5.1e-46 156.9 0.2 1.8e-41 142.1 0.0 2.9 3 0 0 3 3 3 2 Exocyst complex component Sec5 Vps51 PF08700.11 EGO29432.1 - 0.027 14.5 0.1 0.2 11.8 0.0 2.5 3 0 0 3 3 3 0 Vps51/Vps67 Sec15 PF04091.12 EGO29432.1 - 0.048 13.1 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like DUF155 PF02582.14 EGO29433.1 - 8.2e-56 188.9 0.4 1.1e-55 188.5 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Gti1_Pac2 PF09729.9 EGO29435.1 - 8.6e-28 97.6 0.3 4.5e-25 88.8 0.0 2.4 2 1 1 3 3 3 2 Gti1/Pac2 family DUF3395 PF11875.8 EGO29436.1 - 6.4e-35 120.4 0.4 1.9e-34 118.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) HhH-GPD PF00730.25 EGO29436.1 - 4.1e-18 65.8 0.0 1.5e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DnaJ PF00226.31 EGO29436.1 - 3.1e-13 49.6 0.2 8.3e-13 48.3 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain NUDIX_4 PF14815.6 EGO29436.1 - 7.6e-07 29.1 0.0 3.1e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 EGO29436.1 - 0.00011 21.8 0.0 0.00035 20.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SURF4 PF02077.15 EGO29437.1 - 1.1e-92 310.5 10.9 1.2e-92 310.3 10.9 1.0 1 0 0 1 1 1 1 SURF4 family Sugar_tr PF00083.24 EGO29438.1 - 3.1e-112 375.7 20.5 3.7e-112 375.5 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO29438.1 - 1.4e-21 76.8 36.1 4.6e-15 55.4 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO29438.1 - 1e-05 24.2 6.3 1.9e-05 23.3 3.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) ProRS-C_1 PF09180.11 EGO29439.1 - 3.8e-24 84.7 2.0 8.3e-24 83.6 0.4 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGO29439.1 - 4.7e-17 62.5 0.0 9.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGO29439.1 - 5.9e-16 58.4 0.1 1.9e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 EGO29439.1 - 9.4e-12 45.1 0.1 1.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_1 PF00133.22 EGO29440.1 - 7e-156 520.0 0.0 9.2e-156 519.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGO29440.1 - 4.5e-23 81.9 0.4 4.5e-23 81.9 0.4 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGO29440.1 - 1.9e-20 73.0 1.8 1.4e-14 53.6 0.3 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGO29440.1 - 4.3e-05 23.0 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 EGO29440.1 - 0.014 15.3 5.0 0.036 13.9 5.0 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Neuropep_like PF15161.6 EGO29440.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide-like tRNA-synt_1d PF00750.19 EGO29440.1 - 0.089 11.7 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (R) DJ-1_PfpI PF01965.24 EGO29441.1 - 7.1e-39 133.2 0.0 8.2e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 EGO29441.1 - 0.0003 20.4 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 EGO29441.1 - 0.021 14.5 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 EGO29441.1 - 0.049 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like UPF0149 PF03695.13 EGO29442.1 - 0.15 12.4 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) DUF5435 PF17503.2 EGO29443.1 - 1.1 8.9 2.9 1.5 8.5 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) CorA PF01544.18 EGO29444.1 - 3.8e-09 36.3 2.2 6.1e-09 35.6 2.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AbiH PF14253.6 EGO29444.1 - 0.14 12.0 0.8 0.21 11.4 0.8 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Arm-DNA-bind_2 PF12167.8 EGO29444.1 - 0.14 12.1 0.0 28 4.7 0.0 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain AAA PF00004.29 EGO29445.1 - 1.5e-43 148.4 0.0 2.9e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO29445.1 - 4.4e-12 45.6 0.0 1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGO29445.1 - 4.6e-08 33.4 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EGO29445.1 - 1.3e-07 31.4 0.8 3e-07 30.3 0.8 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGO29445.1 - 1.8e-06 28.0 0.0 7.4e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO29445.1 - 6.7e-06 26.6 0.1 7.6e-05 23.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO29445.1 - 4.7e-05 23.7 0.9 0.0063 16.8 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EGO29445.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGO29445.1 - 0.00079 20.0 0.2 0.021 15.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 EGO29445.1 - 0.001 18.3 0.0 0.0022 17.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGO29445.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGO29445.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGO29445.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGO29445.1 - 0.0074 15.8 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EGO29445.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGO29445.1 - 0.011 16.0 0.3 0.022 15.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EGO29445.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGO29445.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 EGO29445.1 - 0.02 14.6 0.0 0.099 12.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGO29445.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 EGO29445.1 - 0.023 15.0 0.2 0.047 13.9 0.2 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF815 PF05673.13 EGO29445.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGO29445.1 - 0.03 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGO29445.1 - 0.034 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO29445.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGO29445.1 - 0.043 14.2 0.0 0.42 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 EGO29445.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EGO29445.1 - 0.073 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGO29445.1 - 0.092 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 EGO29445.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO29445.1 - 0.14 12.1 0.0 0.69 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF5406 PF17400.2 EGO29445.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5406) MR_MLE_C PF13378.6 EGO29446.1 - 1.3e-48 165.4 0.5 1.4e-47 162.1 0.5 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGO29446.1 - 3.1e-08 33.8 0.0 7.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_C25_C PF03785.14 EGO29446.1 - 0.095 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain HET PF06985.11 EGO29449.1 - 4.6e-23 82.2 0.4 9.1e-23 81.2 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIGA PF08288.12 EGO29450.1 - 1.3e-35 121.8 0.9 2.6e-35 120.9 0.2 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EGO29450.1 - 8.3e-24 84.5 1.4 1.6e-23 83.5 1.4 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGO29450.1 - 3.9e-22 78.6 0.0 7.3e-22 77.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO29450.1 - 4.2e-21 75.8 0.2 1.6e-20 73.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGO29450.1 - 4.7e-11 43.4 0.1 8.1e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EGO29450.1 - 0.00017 21.6 0.2 0.00033 20.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EGO29450.1 - 0.00089 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 UNC-50 PF05216.13 EGO29452.1 - 3.5e-87 291.6 14.7 3.9e-87 291.4 14.7 1.0 1 0 0 1 1 1 1 UNC-50 family Metallophos PF00149.28 EGO29453.1 - 7.2e-36 124.6 0.1 1.2e-35 123.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S1-P1_nuclease PF02265.16 EGO29454.1 - 2.7e-45 155.1 0.0 4.4e-43 147.9 0.0 2.6 1 1 0 1 1 1 1 S1/P1 Nuclease Methyltransf_16 PF10294.9 EGO29455.1 - 5.7e-05 22.9 0.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EGO29455.1 - 0.00012 22.0 0.0 0.00035 20.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO29455.1 - 0.064 13.1 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Oxysterol_BP PF01237.18 EGO29456.1 - 5.7e-42 143.9 4.7 9.5e-25 87.2 1.8 3.3 2 1 0 2 2 2 2 Oxysterol-binding protein HofP PF10748.9 EGO29456.1 - 0.032 13.8 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA utilization proteins HofP Sin3a_C PF16879.5 EGO29457.1 - 5e-70 236.5 0.0 8.7e-69 232.4 0.0 2.9 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EGO29457.1 - 1.6e-38 130.7 0.4 6e-38 128.9 0.2 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 EGO29457.1 - 5.9e-34 116.0 3.0 3e-17 62.5 0.0 4.3 3 1 1 4 4 4 3 Paired amphipathic helix repeat Pollen_allerg_1 PF01357.21 EGO29457.1 - 0.17 11.9 0.2 0.42 10.7 0.2 1.6 1 0 0 1 1 1 0 Pollen allergen SPX PF03105.19 EGO29457.1 - 1.9 8.3 9.3 1.6 8.6 4.1 2.6 2 0 0 2 2 2 0 SPX domain bZIP_1 PF00170.21 EGO29458.1 - 3.4e-08 33.4 1.9 6.4e-08 32.6 1.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO29458.1 - 1.4e-05 25.1 5.4 0.0001 22.3 1.8 2.3 1 1 1 2 2 2 2 Basic region leucine zipper IF4E PF01652.18 EGO29460.1 - 1.9e-54 183.8 0.0 2.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AChE_tetra PF08674.10 EGO29461.1 - 0.59 9.9 2.4 11 5.8 0.2 2.3 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain zf-CCHC PF00098.23 EGO29463.1 - 4.3e-07 29.7 1.5 8.7e-07 28.7 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO29463.1 - 2.4e-05 24.5 0.4 6.8e-05 23.1 0.4 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 EGO29463.1 - 0.22 11.4 0.3 0.43 10.4 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 EGO29464.1 - 2.3e-16 59.7 1.6 2.8e-16 59.5 1.6 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PAP2 PF01569.21 EGO29467.1 - 8.4e-16 58.0 12.5 8.4e-16 58.0 12.5 2.2 3 0 0 3 3 3 1 PAP2 superfamily Alpha_kinase PF02816.18 EGO29472.1 - 4.9e-07 30.1 0.0 9.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family zf-CCHC_2 PF13696.6 EGO29474.1 - 0.0019 18.0 0.6 0.0019 18.0 0.6 2.8 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO29474.1 - 0.0066 16.3 2.4 0.015 15.2 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 EGO29475.1 - 2.4e-06 27.8 0.0 4.6e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGO29475.1 - 0.0066 16.5 0.1 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF3527 PF12043.8 EGO29476.1 - 0.0016 18.1 0.2 0.0018 17.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) Retrotran_gag_2 PF14223.6 EGO29479.1 - 1.3e-13 50.7 0.1 1.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO29479.1 - 8.1e-05 22.2 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO29479.1 - 0.0021 17.9 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Spo0A_C PF08769.11 EGO29480.1 - 0.046 13.8 0.6 0.08 13.0 0.6 1.4 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF3713 PF12506.8 EGO29480.1 - 0.21 11.9 1.6 1.9 8.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) CENP-H PF05837.12 EGO29480.1 - 0.23 11.9 7.8 0.07 13.6 4.6 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) tRNA-synt_2 PF00152.20 EGO29481.1 - 5.6e-87 291.8 0.0 6.6e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO29481.1 - 5e-09 36.0 0.2 1.3e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO29481.1 - 0.19 11.2 0.1 2.8 7.4 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) gag_pre-integrs PF13976.6 EGO29482.1 - 2.6e-06 27.2 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain TolA PF06519.11 EGO29482.1 - 0.034 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 TolA C-terminal RT_RNaseH PF17917.1 EGO29485.1 - 2.4e-06 27.8 0.0 4.6e-06 26.9 0.0 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGO29485.1 - 0.0066 16.5 0.1 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-met2 PF12907.7 EGO29486.1 - 8.8e-17 61.0 1.9 1.4e-16 60.3 1.9 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EGO29486.1 - 2.1e-05 25.3 11.2 2.1e-05 25.3 11.2 1.8 2 0 0 2 2 2 1 4F5 protein family zf-PHD-like PF15446.6 EGO29486.1 - 0.021 14.4 1.5 0.024 14.2 1.5 1.0 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-C2H2_12 PF18658.1 EGO29486.1 - 0.1 12.2 0.4 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type NinE PF05322.11 EGO29486.1 - 1.6 8.6 4.7 8.9 6.3 0.3 2.2 1 1 1 2 2 2 0 NINE Protein Beta_elim_lyase PF01212.21 EGO29487.1 - 1.6e-72 244.3 0.0 2.2e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGO29487.1 - 4.9e-06 26.0 0.0 8.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO29487.1 - 0.00095 17.8 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGO29487.1 - 0.073 12.0 0.0 0.34 9.8 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V HTH_33 PF13592.6 EGO29488.1 - 0.13 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix Spore_YtfJ PF09579.10 EGO29489.1 - 0.039 14.1 0.3 0.072 13.3 0.3 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) LSM PF01423.22 EGO29490.1 - 1.8e-19 69.2 1.4 2.3e-19 68.8 1.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO29490.1 - 0.0025 17.9 0.1 0.0032 17.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 EGO29490.1 - 0.018 14.9 0.2 0.037 13.9 0.2 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 EGO29490.1 - 0.13 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Melibiase_2 PF16499.5 EGO29491.1 - 4.1e-54 183.7 4.3 6.7e-54 183.0 4.3 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGO29491.1 - 2.1e-15 56.6 0.3 4.2e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGO29491.1 - 0.0027 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 EGO29492.1 - 5.8e-54 183.2 3.1 9.1e-54 182.5 3.1 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGO29492.1 - 9.3e-15 54.5 0.3 6e-14 51.9 0.1 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGO29492.1 - 2.1e-06 26.9 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Melibiase DDE_Tnp_4 PF13359.6 EGO29494.1 - 1.7e-09 37.6 0.1 2.2e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO29494.1 - 2.4e-05 24.1 0.1 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain TFIIA PF03153.13 EGO29496.1 - 8.9 6.2 20.6 7.8 6.4 17.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_C13 PF01650.18 EGO29498.1 - 1.3e-44 152.7 0.6 1.6e-44 152.4 0.6 1.1 1 0 0 1 1 1 1 Peptidase C13 family WD40 PF00400.32 EGO29499.1 - 3.4e-38 129.0 19.9 2.2e-07 31.5 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29499.1 - 1e-12 48.2 0.1 0.031 14.6 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO29499.1 - 4.5e-08 32.4 0.7 0.46 9.4 0.0 4.7 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGO29499.1 - 3.4e-06 26.1 4.3 0.0014 17.5 0.7 3.6 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 EGO29499.1 - 1e-05 24.5 3.6 0.47 9.0 0.1 3.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 EGO29499.1 - 0.0048 16.3 0.8 0.6 9.4 0.4 2.5 1 1 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region PD40 PF07676.12 EGO29499.1 - 0.03 14.3 0.3 28 4.8 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Arena_nucleocap PF00843.17 EGO29499.1 - 0.098 11.5 0.0 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Arenavirus nucleocapsid N-terminal domain UPF0730 PF15827.5 EGO29500.1 - 0.2 11.4 0.8 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 UPF0730 unknown protein family MR_MLE_C PF13378.6 EGO29501.1 - 4.6e-48 163.7 0.1 3e-47 161.0 0.1 1.9 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGO29501.1 - 1.4e-08 35.0 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EGO29501.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus zf-CCHC PF00098.23 EGO29503.1 - 6.3e-07 29.2 4.8 1.4e-06 28.1 4.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO29503.1 - 9e-07 29.1 0.2 9e-07 29.1 0.2 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Retrotrans_gag PF03732.17 EGO29504.1 - 0.00022 21.4 6.4 0.00034 20.8 3.4 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein NRN1 PF15056.6 EGO29504.1 - 0.061 13.4 2.2 0.15 12.2 1.1 2.0 2 0 0 2 2 2 0 Neuritin protein family Plavaka PF18759.1 EGO29505.1 - 5.3e-18 65.3 0.1 8.4e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase GCV_H PF01597.19 EGO29510.1 - 1.2e-39 135.0 0.1 1.4e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EGO29510.1 - 7.3e-06 25.9 0.7 1.1e-05 25.3 0.7 1.3 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EGO29510.1 - 0.00018 21.3 0.2 0.0004 20.1 0.1 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 EGO29510.1 - 0.033 14.4 0.6 1.6 9.0 0.5 2.2 1 1 1 2 2 2 0 Peptidase family M23 Tropomyosin_1 PF12718.7 EGO29511.1 - 0.00031 20.9 2.6 0.00044 20.4 2.6 1.2 1 0 0 1 1 1 1 Tropomyosin like Spc7 PF08317.11 EGO29511.1 - 0.0037 16.2 2.6 0.0054 15.7 2.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 EGO29511.1 - 0.0093 15.0 1.9 0.014 14.4 1.9 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ERM PF00769.19 EGO29511.1 - 0.013 15.3 5.0 0.02 14.7 5.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF745 PF05335.13 EGO29511.1 - 0.015 15.1 2.3 0.023 14.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Cep57_CLD PF14073.6 EGO29511.1 - 0.021 14.8 4.7 0.033 14.2 4.7 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 ATG16 PF08614.11 EGO29511.1 - 0.022 15.0 7.0 0.076 13.2 7.0 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SOAR PF16533.5 EGO29511.1 - 0.035 14.1 2.1 0.068 13.1 2.1 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region ROS_MUCR PF05443.11 EGO29511.1 - 0.062 13.4 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein T3SSipB PF16535.5 EGO29511.1 - 0.067 13.7 0.8 0.11 13.0 0.8 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB Filo_VP35 PF02097.15 EGO29511.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 DUF3450 PF11932.8 EGO29511.1 - 0.16 11.2 4.2 0.3 10.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FemAB PF02388.16 EGO29511.1 - 0.21 10.4 2.6 0.29 10.0 2.6 1.1 1 0 0 1 1 1 0 FemAB family CENP-Q PF13094.6 EGO29511.1 - 0.25 11.5 3.0 0.5 10.5 3.0 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 EGO29511.1 - 0.27 11.8 3.6 0.18 12.4 1.4 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Spectrin PF00435.21 EGO29511.1 - 0.31 11.6 4.0 0.76 10.3 3.7 1.8 1 1 1 2 2 2 0 Spectrin repeat Spc24 PF08286.11 EGO29511.1 - 0.67 10.2 4.8 0.88 9.8 2.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 EGO29511.1 - 1.4 9.0 8.9 5.6 7.0 8.9 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EGO29511.1 - 2.1 9.0 6.8 5 7.8 0.1 3.1 2 1 1 3 3 2 0 SlyX ABC_tran_CTD PF16326.5 EGO29511.1 - 2.5 8.4 5.6 12 6.2 0.7 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Translin PF01997.16 EGO29512.1 - 9.4e-68 228.2 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Translin family Retrotrans_gag PF03732.17 EGO29515.1 - 1.1e-08 35.2 0.2 1.1e-08 35.2 0.2 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO29515.1 - 0.00037 20.4 3.9 0.00075 19.5 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle adh_short_C2 PF13561.6 EGO29516.1 - 1e-56 192.1 0.6 4.2e-55 186.8 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO29516.1 - 1.9e-41 141.7 5.4 1.2e-39 135.9 5.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO29516.1 - 9.2e-12 45.2 0.3 1.5e-11 44.5 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO29516.1 - 0.0066 15.9 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FUSC_2 PF13515.6 EGO29517.1 - 6.9e-15 55.3 15.0 1.2e-14 54.6 15.0 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGO29517.1 - 1.1e-09 37.4 10.4 2.5e-09 36.2 10.3 1.6 1 1 0 1 1 1 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 EGO29517.1 - 2e-06 27.2 0.5 3e-06 26.6 0.5 1.4 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 EGO29517.1 - 0.0003 19.7 9.7 0.00074 18.5 9.5 1.9 1 1 0 1 1 1 1 Aluminium activated malate transporter ArAE_2 PF10334.9 EGO29517.1 - 0.00041 20.2 2.3 0.00055 19.8 1.3 1.6 1 1 1 2 2 2 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 EGO29517.1 - 0.032 14.4 5.9 0.069 13.3 5.9 1.5 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 DUF5457 PF17540.2 EGO29519.1 - 0.044 13.9 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5457) adh_short_C2 PF13561.6 EGO29520.1 - 1.3e-57 195.0 0.1 1.5e-55 188.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO29520.1 - 4.8e-44 150.2 2.2 7.2e-42 143.0 2.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO29520.1 - 2.1e-10 40.8 1.1 6.8e-10 39.1 1.1 1.7 1 1 0 1 1 1 1 KR domain MRP-L27 PF09809.9 EGO29521.1 - 1.1e-05 25.3 0.1 1.2e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ribo_biogen_C PF04034.13 EGO29522.1 - 1.9e-51 173.1 0.0 2.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGO29522.1 - 3.3e-14 52.4 0.1 5.4e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI EIF_2_alpha PF07541.12 EGO29526.1 - 5.6e-35 119.9 0.0 1.1e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGO29526.1 - 7.6e-13 48.6 0.8 7.6e-13 48.6 0.8 1.9 2 0 0 2 2 2 1 S1 RNA binding domain Wbp11 PF09429.10 EGO29526.1 - 0.028 14.8 1.3 0.11 12.9 0.1 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 GET2 PF08690.10 EGO29526.1 - 1.2 8.7 4.1 15 5.2 0.5 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Ribosomal_60s PF00428.19 EGO29526.1 - 5.3 7.7 12.5 0.12 13.0 3.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein BCDHK_Adom3 PF10436.9 EGO29527.1 - 6.6e-67 224.4 0.0 9.4e-67 223.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGO29527.1 - 3.2e-13 50.1 0.0 8.4e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGO29527.1 - 0.005 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3719 PF12516.8 EGO29527.1 - 0.041 13.6 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Ribosomal_L16 PF00252.18 EGO29528.1 - 5.1e-46 155.9 0.0 6.4e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Hexapep PF00132.24 EGO29529.1 - 3.3e-09 36.1 17.9 0.0011 18.7 1.8 4.1 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO29529.1 - 0.0026 17.5 11.2 0.082 12.7 2.7 2.9 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase FapA PF03961.13 EGO29529.1 - 0.26 9.8 2.4 0.33 9.5 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RTA1 PF04479.13 EGO29530.1 - 1.1e-50 172.1 6.9 1.7e-50 171.5 6.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Alpha-amyl_C PF09071.10 EGO29530.1 - 0.043 13.7 0.2 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 Alpha-amylase, C terminal AAA_13 PF13166.6 EGO29531.1 - 0.0038 16.0 9.3 0.0054 15.5 9.3 1.3 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 EGO29531.1 - 0.024 13.5 15.8 0.062 12.2 15.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein YkyA PF10368.9 EGO29531.1 - 0.45 10.2 18.3 0.49 10.0 6.1 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein YabA PF06156.13 EGO29531.1 - 1.9 9.2 9.2 1.1 9.9 2.8 2.7 1 1 2 3 3 3 0 Initiation control protein YabA NPV_P10 PF05531.12 EGO29531.1 - 2.4 8.7 6.9 1.8 9.1 1.3 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EGO29531.1 - 3.1 7.9 7.1 1.3 9.1 3.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 EGO29531.1 - 6.5 7.5 9.0 5 7.8 1.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) FUSC PF04632.12 EGO29531.1 - 9.1 4.7 7.6 12 4.3 7.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kinesin PF00225.23 EGO29532.1 - 7.7e-94 314.3 0.4 7.7e-94 314.3 0.4 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGO29532.1 - 8.3e-22 77.7 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding TPR_2 PF07719.17 EGO29532.1 - 0.0014 18.6 0.2 0.0027 17.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO29532.1 - 0.0022 17.9 0.1 0.006 16.5 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO29532.1 - 0.005 16.9 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO29532.1 - 0.0063 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO29532.1 - 0.03 15.1 0.1 0.077 13.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO29532.1 - 0.04 14.6 0.1 0.087 13.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TBCC_N PF16752.5 EGO29532.1 - 2.8 8.4 9.0 7.4 7.0 9.0 1.8 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Pkinase PF00069.25 EGO29536.1 - 3.6e-65 220.0 0.0 4.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29536.1 - 8.1e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO29536.1 - 0.00012 21.5 0.1 0.00019 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO29536.1 - 0.0037 17.2 0.6 0.51 10.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO29536.1 - 0.0039 16.2 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO29536.1 - 0.0041 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGO29536.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 p450 PF00067.22 EGO29537.1 - 1.5e-57 195.3 0.0 6.5e-56 190.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO29539.1 - 1.2e-62 212.2 0.0 3.8e-62 210.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Arm PF00514.23 EGO29543.1 - 4.3e-06 26.6 0.0 0.76 9.9 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 EGO29543.1 - 0.0022 17.3 0.1 0.18 11.1 0.1 2.5 1 1 1 2 2 2 2 V-ATPase subunit H WAPL PF07814.13 EGO29543.1 - 0.072 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Guanylin PF02058.15 EGO29545.1 - 0.12 12.9 1.1 0.85 10.1 0.2 2.3 2 1 1 3 3 3 0 Guanylin precursor DUF2235 PF09994.9 EGO29547.1 - 5.1e-50 170.4 0.0 6.3e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sars6 PF12133.8 EGO29547.1 - 0.3 11.0 1.5 17 5.5 0.3 2.3 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus Abhydrolase_3 PF07859.13 EGO29549.1 - 1.9e-43 148.8 0.0 6.6e-43 147.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO29549.1 - 4.8e-11 42.1 0.0 1.3e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EGO29549.1 - 0.055 12.3 0.0 0.32 9.8 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.21 EGO29549.1 - 0.22 11.0 0.0 15 5.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family SLBP_RNA_bind PF15247.6 EGO29551.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain MFS_1 PF07690.16 EGO29553.1 - 1.3e-41 142.7 44.0 1.3e-41 142.7 44.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO29553.1 - 7.9e-19 67.5 23.2 7.9e-19 67.5 23.2 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO29553.1 - 2.8e-13 49.5 8.4 2.8e-13 49.5 8.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EGO29553.1 - 0.0019 16.6 3.6 0.0019 16.6 3.6 2.6 2 2 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sec23_trunk PF04811.15 EGO29555.1 - 2.1e-47 161.7 0.0 3.4e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGO29555.1 - 2.6e-20 72.1 0.2 4.7e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGO29555.1 - 3.6e-17 62.9 0.1 8.6e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGO29555.1 - 1.2e-13 50.8 5.1 3.1e-13 49.5 5.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGO29555.1 - 0.00042 20.2 0.0 0.00086 19.2 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat MRNIP PF15749.5 EGO29555.1 - 0.18 12.5 0.9 0.35 11.6 0.9 1.4 1 0 0 1 1 1 0 MRN-interacting protein PKcGMP_CC PF16808.5 EGO29557.1 - 0.034 14.0 0.7 0.16 11.8 0.7 2.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 EGO29557.1 - 0.074 13.2 0.4 0.074 13.2 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PFL-like PF02901.15 EGO29557.1 - 0.087 11.4 0.6 0.17 10.5 0.6 1.4 1 0 0 1 1 1 0 Pyruvate formate lyase-like Spc42p PF11544.8 EGO29557.1 - 0.13 12.3 2.1 0.31 11.0 0.1 2.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF1192 PF06698.11 EGO29557.1 - 2.2 8.4 7.2 13 6.0 0.7 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF2855 PF11017.8 EGO29558.1 - 1.8e-109 366.6 0.0 2e-109 366.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DSPc PF00782.20 EGO29559.1 - 3.7e-24 85.0 0.0 5.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO29559.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4195 PF13836.6 EGO29560.1 - 0.037 14.2 0.3 0.04 14.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Methyltrans_SAM PF10672.9 EGO29560.1 - 0.073 12.2 0.0 0.083 12.0 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase RNA_pol_L_2 PF13656.6 EGO29562.1 - 1.3e-26 92.2 0.0 1.7e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGO29562.1 - 1.7e-07 30.5 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_6 PF00970.24 EGO29566.1 - 1.3e-33 115.3 0.0 2.7e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGO29566.1 - 7.1e-32 110.3 0.0 1.1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGO29566.1 - 6.1e-05 23.2 0.0 0.0038 17.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGO29566.1 - 0.0079 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain RRM_1 PF00076.22 EGO29568.1 - 4.7e-18 64.8 0.0 1.6e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO29568.1 - 0.0068 16.0 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO29568.1 - 0.074 13.2 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif ATPase PF06745.13 EGO29569.1 - 7.4e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 EGO29569.1 - 0.00015 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EGO29569.1 - 0.00039 19.8 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 IstB_IS21 PF01695.17 EGO29569.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein PIG-P PF08510.12 EGO29570.1 - 8.3e-32 109.7 6.0 1.1e-31 109.3 6.0 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EGO29570.1 - 0.036 14.4 8.4 0.071 13.4 8.4 1.5 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) APC_u14 PF16635.5 EGO29570.1 - 0.042 14.4 0.2 0.06 13.9 0.2 1.2 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr zf-C2H2 PF00096.26 EGO29571.1 - 1.3e-10 41.1 10.3 6.2e-06 26.4 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO29571.1 - 1.2e-07 31.8 10.6 9e-05 22.7 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO29571.1 - 2.1e-06 28.0 9.1 0.00038 21.1 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO29571.1 - 3.6e-05 23.9 2.1 0.008 16.4 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO29571.1 - 5.5e-05 23.4 4.8 0.0018 18.6 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGO29571.1 - 0.0033 17.4 0.5 0.0033 17.4 0.5 2.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGO29571.1 - 0.024 14.6 1.9 0.89 9.5 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-WRNIP1_ubi PF18279.1 EGO29571.1 - 0.037 14.7 1.7 0.13 13.0 1.7 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-BED PF02892.15 EGO29571.1 - 0.29 11.2 7.7 2 8.5 1.3 2.5 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.6 EGO29571.1 - 0.4 10.7 4.1 11 6.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 EGO29571.1 - 0.43 10.9 6.7 0.26 11.6 1.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GP40 PF11025.8 EGO29572.1 - 0.063 13.0 0.1 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium XPG_N PF00752.17 EGO29573.1 - 1.7e-25 89.4 0.0 3.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGO29573.1 - 2.8e-25 88.5 0.0 5.6e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGO29573.1 - 1.6e-05 24.5 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EGO29573.1 - 9.5e-05 22.9 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 EGO29573.1 - 0.031 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO29573.1 - 0.06 13.5 0.5 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Dioxygenase_C PF00775.21 EGO29574.1 - 1.2e-40 138.9 0.0 1.6e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EGO29574.1 - 6.6e-29 99.6 0.0 1.1e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Calsequestrin PF01216.17 EGO29574.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Calsequestrin p450 PF00067.22 EGO29576.1 - 3.8e-50 171.0 0.0 7.6e-49 166.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 HMG_box PF00505.19 EGO29578.1 - 0.0006 20.2 1.2 0.00089 19.6 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO29578.1 - 0.0024 18.4 0.9 0.0036 17.9 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain AP4E_app_platf PF14807.6 EGO29578.1 - 0.065 13.6 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DKNYY PF13644.6 EGO29583.1 - 0.0071 17.1 0.6 0.0088 16.8 0.6 1.1 1 0 0 1 1 1 1 DKNYY family DUF1823 PF08853.11 EGO29583.1 - 0.035 14.3 0.2 0.038 14.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) DUF4939 PF16297.5 EGO29583.1 - 0.037 13.9 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DFP PF04127.15 EGO29585.1 - 3.1e-20 72.8 0.0 8.3e-12 45.3 0.0 2.3 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Hydrophobin PF01185.18 EGO29586.1 - 1.3e-16 61.0 12.0 1.7e-16 60.6 12.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin SIS PF01380.22 EGO29588.1 - 1.7e-63 212.3 0.2 2.5e-33 114.7 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGO29588.1 - 1.2e-15 57.9 0.0 2.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGO29588.1 - 1.1e-11 44.7 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGO29588.1 - 6.2e-05 22.0 0.0 9.7e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EGO29588.1 - 0.069 13.2 0.0 0.74 9.8 0.0 2.4 1 1 1 2 2 2 0 SIS domain GATase_2 PF00310.21 EGO29588.1 - 0.1 11.3 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Abhydrolase_1 PF00561.20 EGO29590.1 - 3.7e-23 82.5 0.2 4.6e-22 78.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO29590.1 - 2.7e-18 67.4 14.2 8.7e-17 62.5 14.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO29590.1 - 6.8e-09 35.3 0.0 2.2e-08 33.7 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EGO29590.1 - 0.0095 14.7 0.1 1.6 7.3 0.0 2.2 2 0 0 2 2 2 2 Ndr family Abhydrolase_8 PF06259.12 EGO29590.1 - 0.072 12.7 0.5 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Chlorophyllase2 PF12740.7 EGO29590.1 - 0.1 11.5 0.0 0.46 9.4 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Esterase PF00756.20 EGO29590.1 - 0.32 10.6 2.2 1.6 8.3 0.3 2.5 3 0 0 3 3 3 0 Putative esterase DUF667 PF05018.13 EGO29591.1 - 1.3e-18 67.4 0.0 1.2e-08 34.9 0.0 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF667) PDEase_I PF00233.19 EGO29599.1 - 4.2e-57 193.6 1.1 8.3e-56 189.4 0.2 2.7 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Adeno_E1B_19K PF01691.16 EGO29599.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Methyltransf_16 PF10294.9 EGO29600.1 - 1.3e-11 44.5 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MutS_V PF00488.21 EGO29601.1 - 5.9e-56 189.5 0.2 1.1e-55 188.5 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO29601.1 - 1.1e-36 126.9 0.2 2.9e-36 125.5 0.2 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGO29601.1 - 2.8e-17 63.0 0.0 7.6e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGO29601.1 - 9.3e-10 38.9 0.0 4.7e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EGO29601.1 - 0.00037 20.8 0.0 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV Glyco_hydro_16 PF00722.21 EGO29602.1 - 1.6e-37 128.7 1.8 2.1e-37 128.3 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EGO29602.1 - 0.043 14.3 15.1 0.1 13.1 15.1 1.6 1 0 0 1 1 1 0 Chitin recognition protein p450 PF00067.22 EGO29603.1 - 4.9e-22 78.3 0.0 6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO29604.1 - 6.8e-10 38.3 0.1 7.2e-10 38.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 EGO29605.1 - 8.8e-13 47.9 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGO29605.1 - 1.4e-06 28.8 0.6 3.2e-06 27.6 0.6 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.19 EGO29605.1 - 0.0081 16.7 0.1 0.023 15.3 0.1 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Formyl_trans_N PF00551.19 EGO29606.1 - 1e-24 87.3 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGO29606.1 - 4e-08 33.4 0.0 8.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.16 EGO29607.1 - 1.5e-25 89.9 35.1 1.5e-25 89.9 35.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 EGO29607.1 - 0.0069 16.7 8.8 0.13 12.6 3.2 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF1772) WD40 PF00400.32 EGO29608.1 - 3.1e-30 103.8 19.1 7.2e-07 29.8 0.7 11.0 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29608.1 - 6.6e-14 52.0 0.1 0.00021 21.5 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGO29608.1 - 1.1e-05 25.2 6.8 0.0089 15.6 1.6 3.5 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 EGO29608.1 - 2.2e-05 24.8 9.4 0.33 11.5 0.3 5.6 5 0 0 5 5 5 2 PQQ-like domain Kelch_6 PF13964.6 EGO29608.1 - 0.0034 17.6 0.6 0.34 11.3 0.0 3.9 3 1 0 3 3 3 1 Kelch motif CPSF_A PF03178.15 EGO29608.1 - 0.0083 15.5 0.0 3.9 6.7 0.0 2.6 3 0 0 3 3 3 2 CPSF A subunit region Nup160 PF11715.8 EGO29608.1 - 0.0098 14.6 2.1 0.078 11.6 0.5 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO29608.1 - 0.011 14.8 0.5 2.7 6.9 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGO29608.1 - 0.013 14.8 1.1 10 5.3 0.0 3.4 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Mad3_BUB1_I PF08311.12 EGO29609.1 - 2.2e-33 114.9 0.1 3.5e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Cupin_1 PF00190.22 EGO29611.1 - 1e-42 145.3 0.1 1e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGO29611.1 - 3.2e-26 90.8 0.3 9.6e-13 47.7 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGO29611.1 - 4.4e-09 35.9 0.1 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EGO29611.1 - 0.00011 22.2 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EGO29611.1 - 0.0013 18.7 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_8 PF13621.6 EGO29611.1 - 0.015 15.0 0.0 0.11 12.2 0.0 2.1 1 1 0 2 2 2 0 Cupin-like domain Cupin_6 PF12852.7 EGO29611.1 - 0.019 14.7 0.0 0.32 10.7 0.0 2.3 1 1 0 2 2 2 0 Cupin RRM_1 PF00076.22 EGO29612.1 - 1e-34 118.1 0.0 8.7e-20 70.3 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGO29612.1 - 1e-07 32.0 0.1 0.00052 20.1 0.0 3.3 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 EGO29612.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EGO29612.1 - 0.22 11.5 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.16 EGO29613.1 - 6.7e-31 107.5 27.6 1e-30 106.9 27.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3267 PF11667.8 EGO29613.1 - 1.9 8.8 12.9 1 9.7 2.6 3.2 2 1 0 2 2 2 0 Putative zincin peptidase DUF1772 PF08592.11 EGO29613.1 - 7.9 6.8 15.3 0.36 11.2 2.1 4.1 4 2 1 5 5 5 0 Domain of unknown function (DUF1772) Sterol_MT_C PF08498.10 EGO29614.1 - 5.3e-29 100.3 0.1 8.5e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 EGO29614.1 - 2.4e-18 66.4 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO29614.1 - 6.4e-18 65.2 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO29614.1 - 8.4e-17 61.7 0.0 1.5e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO29614.1 - 3.9e-14 52.6 0.0 5.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGO29614.1 - 8.2e-12 45.7 0.1 2.2e-11 44.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO29614.1 - 8.6e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO29614.1 - 4.6e-08 32.7 0.0 9.6e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGO29614.1 - 5e-06 26.4 0.0 7.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EGO29614.1 - 0.00019 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 EGO29614.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.17 EGO29614.1 - 0.0013 18.2 0.0 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EGO29614.1 - 0.0017 18.0 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EGO29614.1 - 0.002 19.1 0.0 0.0082 17.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGO29614.1 - 0.0024 17.6 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.18 EGO29614.1 - 0.0049 16.2 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 EGO29614.1 - 0.0096 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EGO29614.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EGO29614.1 - 0.046 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 EGO29614.1 - 0.076 13.0 0.1 0.15 12.0 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.20 EGO29614.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Rad52_Rad22 PF04098.15 EGO29616.1 - 8.8e-56 188.1 0.0 1.4e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein p450 PF00067.22 EGO29617.1 - 7.2e-66 222.8 0.0 9.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mitoc_mL59 PF18126.1 EGO29620.1 - 1e-40 139.0 5.2 1.4e-40 138.6 5.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 PH_9 PF15410.6 EGO29623.1 - 0.00022 21.6 0.0 0.00028 21.2 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGO29623.1 - 0.024 15.2 0.0 0.028 14.9 0.0 1.1 1 0 0 1 1 1 0 PH domain Metallophos PF00149.28 EGO29624.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO29624.1 - 9.9e-22 77.1 0.5 2.1e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Sugar_tr PF00083.24 EGO29625.1 - 4.5e-84 282.9 23.2 5.2e-84 282.7 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO29625.1 - 3.7e-24 85.3 36.9 1.4e-20 73.6 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1769 PF08588.10 EGO29626.1 - 4.7e-23 81.1 0.7 8.8e-23 80.3 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SR-25 PF10500.9 EGO29626.1 - 0.056 13.0 8.2 0.078 12.6 8.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short_C2 PF13561.6 EGO29628.1 - 5.6e-56 189.7 0.1 6.7e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO29628.1 - 1.7e-41 141.8 0.1 2.7e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO29628.1 - 4.9e-15 55.9 0.3 6.1e-15 55.6 0.3 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGO29628.1 - 2.5e-05 23.4 0.1 3e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO29628.1 - 0.00011 21.7 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGO29628.1 - 0.00082 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGO29628.1 - 0.0014 18.1 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase His_biosynth PF00977.21 EGO29628.1 - 0.0033 16.9 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Pyr_redox PF00070.27 EGO29628.1 - 0.0047 17.4 0.1 0.01 16.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO29628.1 - 0.0065 15.8 0.3 0.011 15.1 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EGO29628.1 - 0.0094 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGO29628.1 - 0.038 13.9 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EGO29628.1 - 0.074 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DEAD PF00270.29 EGO29629.1 - 2.5e-42 144.6 0.2 4.5e-42 143.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO29629.1 - 1.1e-27 96.6 0.8 1.1e-26 93.3 0.3 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO29629.1 - 5.6e-06 26.5 0.1 1.2e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGO29629.1 - 0.013 14.8 0.1 0.03 13.7 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 EGO29629.1 - 0.027 14.9 0.1 1.3 9.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Terpene_synth_C PF03936.16 EGO29630.1 - 3.9e-07 29.7 0.0 5.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 EGO29630.1 - 0.00086 19.4 0.2 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 Sporulation initiation phospho-transferase B, C-terminal UPF0113 PF03657.13 EGO29630.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 UPF0113 PUA domain MFS_1 PF07690.16 EGO29631.1 - 2.8e-26 92.3 26.9 3.8e-20 72.1 6.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO29631.1 - 4e-05 22.7 4.0 4e-05 22.7 4.0 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGO29631.1 - 0.028 13.3 0.4 0.028 13.3 0.4 3.3 2 1 1 3 3 3 0 MFS_1 like family WD40 PF00400.32 EGO29632.1 - 1.1e-09 38.8 21.3 0.037 14.9 0.1 8.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29632.1 - 5.4e-06 26.6 0.0 0.029 14.7 0.0 5.1 5 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO29632.1 - 0.08 12.9 0.3 17 5.5 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Sdh5 PF03937.16 EGO29633.1 - 1e-29 102.3 0.9 1.2e-29 102.1 0.9 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Gly_transf_sug PF04488.15 EGO29634.1 - 6e-07 30.0 0.0 9.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGO29634.1 - 0.0049 16.3 0.1 0.0072 15.7 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein F-box-like PF12937.7 EGO29635.1 - 8.1e-07 28.8 3.8 8.1e-07 28.8 3.8 3.5 3 0 0 3 3 3 1 F-box-like DUF5082 PF16888.5 EGO29635.1 - 0.08 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) F-box PF00646.33 EGO29635.1 - 0.11 12.4 12.5 0.36 10.8 0.9 4.5 5 0 0 5 5 5 0 F-box domain gag-asp_proteas PF13975.6 EGO29636.1 - 3e-05 24.5 0.0 4.2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO29636.1 - 0.00012 22.7 0.0 0.00017 22.2 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO29636.1 - 0.0038 17.0 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EGO29637.1 - 6.5e-07 29.5 1.2 6.5e-07 29.5 1.2 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein M64_N PF16217.5 EGO29637.1 - 0.011 15.3 0.1 0.038 13.6 0.1 2.0 2 1 0 2 2 2 0 Peptidase M64 N-terminus DUF4939 PF16297.5 EGO29637.1 - 0.014 15.3 0.1 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) zf-CCHC_3 PF13917.6 EGO29638.1 - 9.8e-07 28.6 1.2 2.3e-06 27.4 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO29638.1 - 9.5e-06 25.5 5.1 1.4e-05 24.9 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO29638.1 - 0.037 13.5 0.7 0.067 12.7 0.7 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain DUF4748 PF15932.5 EGO29640.1 - 4.4e-05 23.2 0.0 5.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) DUF3929 PF13066.6 EGO29640.1 - 0.052 13.6 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) WD40 PF00400.32 EGO29642.1 - 3.3e-46 154.3 17.0 2.5e-07 31.3 0.1 12.6 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29642.1 - 1.9e-26 92.2 0.0 0.0023 18.2 0.0 9.9 3 2 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGO29642.1 - 2.1e-25 89.1 0.0 3.1e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EGO29642.1 - 4.3e-11 42.4 5.0 0.38 9.6 0.0 7.2 4 3 3 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO29642.1 - 5.8e-06 26.1 0.6 6.1 6.9 0.0 7.3 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EGO29642.1 - 8e-05 22.5 0.0 0.2 11.4 0.0 3.8 3 2 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 EGO29642.1 - 0.00091 18.0 0.0 0.88 8.1 0.0 3.5 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EGO29642.1 - 0.0035 16.7 0.2 27 4.0 0.0 4.6 3 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EGO29642.1 - 0.011 15.0 0.1 0.82 8.9 0.0 3.8 6 0 0 6 6 6 0 WD40-like domain RAB3GAP2_N PF14655.6 EGO29642.1 - 0.023 14.0 0.0 0.55 9.4 0.0 3.3 4 2 2 6 6 6 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 EGO29642.1 - 0.038 12.6 0.0 0.12 10.9 0.0 1.8 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin DEAD PF00270.29 EGO29645.1 - 1.8e-39 135.3 0.2 7.2e-21 74.7 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO29645.1 - 3e-27 95.2 0.0 1.6e-25 89.6 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO29645.1 - 8.5e-06 25.9 0.0 2.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vps36-NZF-N PF16988.5 EGO29646.1 - 0.008 15.5 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 EGO29647.1 - 9.4e-64 215.3 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29647.1 - 2.5e-27 95.8 0.0 3.7e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO29647.1 - 4.9e-06 26.1 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO29647.1 - 0.00028 20.3 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO29647.1 - 0.0005 19.7 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGO29647.1 - 0.0043 17.0 0.2 0.57 10.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO29647.1 - 0.026 13.5 0.2 0.059 12.3 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DUF4723 PF15851.5 EGO29648.1 - 0.1 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4723) Glutaredoxin PF00462.24 EGO29650.1 - 9.1e-18 64.2 0.0 3e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Herpes_ori_bp PF02399.15 EGO29650.1 - 0.0032 15.6 0.0 0.0035 15.5 0.0 1.0 1 0 0 1 1 1 1 Origin of replication binding protein Sec62 PF03839.16 EGO29651.1 - 4.4e-49 166.9 5.9 1.7e-48 165.0 5.9 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 p450 PF00067.22 EGO29652.1 - 1.1e-76 258.5 0.0 1.5e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rad17 PF03215.15 EGO29654.1 - 2.3e-25 89.6 0.0 9.7e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGO29654.1 - 0.00011 22.4 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 EGO29654.1 - 0.00016 22.1 0.3 0.00054 20.4 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGO29654.1 - 0.006 17.0 0.0 0.022 15.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGO29654.1 - 0.031 14.0 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO29654.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO29654.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EGO29654.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MBA1 PF07961.11 EGO29655.1 - 2.5e-05 23.4 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 EGO29655.1 - 0.025 14.7 0.1 0.061 13.4 0.1 1.6 1 1 0 1 1 1 0 Tim44-like domain Hamartin PF04388.12 EGO29655.1 - 1.5 7.4 7.2 1.6 7.3 7.2 1.1 1 0 0 1 1 1 0 Hamartin protein GST_N_3 PF13417.6 EGO29656.1 - 4.5e-17 62.2 0.0 7.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO29656.1 - 6.6e-17 61.5 0.0 8.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO29656.1 - 4.6e-16 58.9 0.0 9.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO29656.1 - 1.8e-09 37.7 0.0 3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO29656.1 - 2.2e-08 34.0 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO29656.1 - 6e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGO29656.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3746 PF12562.8 EGO29657.1 - 0.12 12.3 0.3 0.3 11.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) GST_C PF00043.25 EGO29658.1 - 3.3e-16 59.3 0.0 5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO29658.1 - 1.1e-15 57.7 0.0 2.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO29658.1 - 2.8e-14 53.3 0.0 4.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO29658.1 - 1.3e-09 38.2 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO29658.1 - 2.7e-07 30.5 0.0 4.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO29658.1 - 2e-06 27.9 0.0 3.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO29659.1 - 4.1e-18 65.5 0.0 1.5e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO29659.1 - 6.1e-17 61.8 0.0 3.2e-16 59.5 0.1 2.0 1 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO29659.1 - 9.6e-14 51.4 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO29659.1 - 2.5e-10 40.5 0.0 4.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO29659.1 - 4e-06 26.9 0.0 7.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO29659.1 - 0.00071 19.6 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 EGO29661.1 - 3.6e-72 243.6 0.0 1.5e-71 241.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 TrmO_C PF18389.1 EGO29661.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain Glyco_hydro_47 PF01532.20 EGO29662.1 - 1.9e-115 386.4 0.9 5.3e-83 279.4 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 DUF4771 PF15995.5 EGO29663.1 - 0.086 13.1 0.1 0.32 11.2 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4771) DUF4795 PF16043.5 EGO29663.1 - 0.39 10.3 2.1 8 6.0 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Sec20 PF03908.13 EGO29664.1 - 2.2e-16 59.5 2.7 2.2e-16 59.5 2.7 2.2 2 0 0 2 2 2 1 Sec20 Ran-binding PF05508.11 EGO29664.1 - 0.085 11.8 5.9 0.034 13.1 1.3 2.0 2 0 0 2 2 2 0 RanGTP-binding protein NPV_P10 PF05531.12 EGO29664.1 - 0.11 12.9 8.7 0.26 11.8 1.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 EGO29664.1 - 1.3 9.7 11.6 11 6.6 0.9 3.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF16 PF01519.16 EGO29664.1 - 1.7 9.2 5.3 0.68 10.4 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 PHD PF00628.29 EGO29665.1 - 6.7e-09 35.5 4.2 1.2e-08 34.7 4.2 1.4 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.24 EGO29665.1 - 3.9e-05 23.5 0.1 7e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain C1_1 PF00130.22 EGO29665.1 - 0.078 12.9 1.0 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1936 PF09151.10 EGO29665.1 - 0.24 11.3 5.7 0.76 9.7 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1936) DUF4470 PF14737.6 EGO29667.1 - 5.7e-22 77.7 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGO29667.1 - 8.6e-10 38.6 11.7 2e-09 37.4 11.7 1.7 1 0 0 1 1 1 1 MYND finger DUF4413 PF14372.6 EGO29667.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) zf-C6H2 PF15801.5 EGO29667.1 - 4 7.8 10.7 13 6.2 10.7 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-CCHC_3 PF13917.6 EGO29668.1 - 0.22 11.5 3.9 0.57 10.2 3.9 1.7 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_2 PF13240.6 EGO29668.1 - 3.4 7.5 7.8 0.67 9.7 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_6 PF15288.6 EGO29670.1 - 0.051 13.4 0.9 0.91 9.4 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO29670.1 - 0.057 13.1 1.6 0.088 12.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGO29670.1 - 0.094 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger DUF4470 PF14737.6 EGO29671.1 - 1.8e-23 82.5 0.0 3.7e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGO29671.1 - 3.6e-10 39.7 13.1 9e-10 38.5 13.1 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO29671.1 - 1.7 9.0 11.2 5.2 7.5 11.2 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding FMO-like PF00743.19 EGO29672.1 - 3.4e-31 108.3 0.0 5.6e-18 64.7 0.0 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO29672.1 - 1.5e-12 47.5 0.0 1.1e-08 34.8 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO29672.1 - 1.6e-06 27.6 0.0 0.0042 16.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO29672.1 - 0.0012 18.0 0.0 0.072 12.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGO29672.1 - 0.14 12.1 0.5 8.6 6.3 0.5 3.1 2 1 0 2 2 2 0 FAD-NAD(P)-binding zf-C3HC4_3 PF13920.6 EGO29673.1 - 5.6e-13 48.5 7.8 5.6e-13 48.5 7.8 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO29673.1 - 4.7e-09 36.0 6.3 4.7e-09 36.0 6.3 2.4 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 FYVE PF01363.21 EGO29673.1 - 8.1e-07 29.1 3.9 8.1e-07 29.1 3.9 3.0 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 EGO29673.1 - 1.1e-06 28.8 6.6 1.1e-06 28.8 6.6 2.5 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGO29673.1 - 3.4e-05 23.6 8.4 3.4e-05 23.6 8.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.9 EGO29673.1 - 0.00039 20.4 0.1 0.44 10.5 0.0 2.4 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding zf-C3HC4_2 PF13923.6 EGO29673.1 - 0.0011 18.8 7.8 0.0011 18.8 7.8 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 EGO29673.1 - 0.0033 17.6 2.4 0.0033 17.6 2.4 3.1 3 1 0 3 3 2 1 FYVE-type zinc finger zf-P11 PF03854.14 EGO29673.1 - 0.0045 16.6 4.3 0.0045 16.6 4.3 3.0 3 1 0 3 3 3 1 P-11 zinc finger DUF1682 PF07946.14 EGO29673.1 - 0.011 15.0 2.0 0.015 14.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4518 PF15008.6 EGO29673.1 - 0.019 14.2 1.4 1.1 8.4 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) DUF4746 PF15928.5 EGO29673.1 - 0.36 10.2 4.3 0.5 9.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-RING_5 PF14634.6 EGO29673.1 - 1.1 9.3 20.4 0.051 13.5 5.9 2.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-UDP PF14569.6 EGO29673.1 - 1.7 8.9 10.8 0.45 10.7 2.9 2.9 2 0 0 2 2 2 0 Zinc-binding RING-finger CPSF100_C PF13299.6 EGO29673.1 - 1.7 8.8 6.9 0.2 11.8 2.0 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.12 EGO29673.1 - 2.6 5.9 4.3 4 5.3 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PRTP PF01366.18 EGO29673.1 - 3.8 5.4 5.4 16 3.4 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus processing and transport protein zf-RING_4 PF14570.6 EGO29673.1 - 4 7.3 18.2 0.65 9.8 5.1 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RSN1_7TM PF02714.15 EGO29674.1 - 2.1e-77 260.1 23.8 2.1e-77 260.1 23.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGO29674.1 - 1.9e-36 125.2 5.5 5.4e-36 123.7 5.5 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGO29674.1 - 2.9e-29 102.5 0.0 4.4e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGO29674.1 - 1.3e-11 44.5 0.0 3.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Ran-binding PF05508.11 EGO29675.1 - 0.053 12.5 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 RanGTP-binding protein Glyco_hydro_72 PF03198.14 EGO29676.1 - 1.3e-94 317.0 0.1 1.8e-94 316.5 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGO29676.1 - 4.2e-20 72.2 4.3 4.2e-20 72.2 4.3 2.1 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 EGO29676.1 - 0.009 15.5 0.1 0.02 14.3 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 EGO29677.1 - 3.4e-102 342.6 0.0 6.2e-56 190.1 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 LPD7 PF18821.1 EGO29677.1 - 0.0021 18.1 0.1 2 8.6 0.0 2.9 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 7 DUF777 PF05606.11 EGO29677.1 - 0.017 14.9 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF777) RinB PF06116.12 EGO29677.1 - 0.12 12.5 3.3 1 9.5 0.2 2.7 2 0 0 2 2 2 0 Transcriptional activator RinB VPS11_C PF12451.8 EGO29677.1 - 0.74 10.1 3.3 23 5.3 0.4 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Syntaxin-6_N PF09177.11 EGO29678.1 - 9.5e-27 93.5 5.1 4.2e-26 91.4 0.4 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EGO29678.1 - 2.1e-09 37.2 0.7 5.1e-09 36.0 0.7 1.7 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EGO29678.1 - 0.00026 20.8 0.8 0.00053 19.8 0.2 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 EGO29678.1 - 0.0011 17.0 0.3 0.0037 15.3 0.1 1.7 1 1 1 2 2 2 1 Prominin HMMR_N PF15905.5 EGO29678.1 - 0.0019 17.7 1.3 0.41 10.1 0.2 2.1 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EGO29678.1 - 0.0034 16.3 5.0 0.074 11.9 0.2 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein HisKA_3 PF07730.13 EGO29678.1 - 0.0094 16.5 0.4 0.0094 16.5 0.4 3.1 2 1 0 2 2 2 1 Histidine kinase XhlA PF10779.9 EGO29678.1 - 0.016 15.4 0.2 1.1 9.5 0.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF3040 PF11239.8 EGO29678.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4407 PF14362.6 EGO29678.1 - 0.026 13.9 2.3 0.14 11.5 2.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 EGO29678.1 - 0.028 14.6 6.3 2.3 8.4 1.2 3.0 2 2 1 3 3 3 0 Flagellar FliJ protein Laminin_II PF06009.12 EGO29678.1 - 0.05 13.6 2.3 1.8 8.6 0.0 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF1640 PF07798.11 EGO29678.1 - 0.076 13.1 5.5 1.9 8.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) FlaC_arch PF05377.11 EGO29678.1 - 0.081 13.3 6.7 2 8.9 0.2 4.1 3 2 2 5 5 4 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 EGO29678.1 - 0.098 12.9 3.6 0.54 10.6 0.1 2.7 2 1 0 2 2 2 0 Rx N-terminal domain DUF641 PF04859.12 EGO29678.1 - 0.11 12.9 5.0 0.22 11.9 0.4 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Uso1_p115_C PF04871.13 EGO29678.1 - 0.17 12.3 4.2 1.2 9.5 0.1 2.6 2 2 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 EGO29678.1 - 0.18 11.6 3.4 1.6 8.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) T2SSF PF00482.23 EGO29678.1 - 0.19 11.7 3.5 0.63 10.0 0.4 2.8 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F Tropomyosin_1 PF12718.7 EGO29678.1 - 0.22 11.7 3.5 5.3 7.2 0.5 2.4 2 0 0 2 2 2 0 Tropomyosin like Cnn_1N PF07989.11 EGO29678.1 - 0.39 10.9 5.8 0.51 10.5 0.3 3.2 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF773 PF05600.12 EGO29678.1 - 0.45 9.2 3.0 0.39 9.4 0.5 1.9 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 DUF1664 PF07889.12 EGO29678.1 - 0.47 10.5 4.2 12 5.9 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 EGO29678.1 - 0.78 9.1 7.9 6.4 6.1 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EGO29678.1 - 2.2 8.7 8.3 7.9 6.9 0.5 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) Lebercilin PF15619.6 EGO29678.1 - 2.7 7.6 7.9 2 8.0 0.3 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 EGO29678.1 - 4.6 7.6 6.2 12 6.2 1.1 3.0 3 1 0 3 3 3 0 Uncharacterized conserved protein Jnk-SapK_ap_N PF09744.9 EGO29678.1 - 4.7 7.4 10.0 0.44 10.8 0.7 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF5446 PF17522.2 EGO29678.1 - 7.2 6.9 8.4 0.62 10.3 0.2 2.9 3 1 1 4 4 3 0 Family of unknown function (DUF5446) DUF4470 PF14737.6 EGO29679.1 - 1.4e-16 60.4 0.1 8.7e-16 57.9 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGO29679.1 - 4.3e-06 26.7 10.1 1.7e-05 24.8 10.1 2.1 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGO29679.1 - 6.5 6.7 9.8 16 5.4 9.8 1.8 1 0 0 1 1 1 0 HIT zinc finger ADH_zinc_N PF00107.26 EGO29681.1 - 1.6e-28 99.3 0.6 2.9e-28 98.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO29681.1 - 3.8e-28 97.5 2.0 6.7e-28 96.8 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO29681.1 - 2.1e-07 32.0 0.1 3.3e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGO29681.1 - 0.11 12.0 0.3 0.59 9.6 0.5 2.2 3 1 0 3 3 3 0 short chain dehydrogenase MerT PF02411.15 EGO29681.1 - 0.14 12.2 0.3 0.45 10.6 0.3 1.9 1 0 0 1 1 1 0 MerT mercuric transport protein Fer4_18 PF13746.6 EGO29681.1 - 0.16 12.2 2.5 2.6 8.3 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGO29681.1 - 0.17 12.4 2.4 2.3 8.7 0.3 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain AAA PF00004.29 EGO29682.1 - 3.9e-19 69.4 0.0 5.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO29682.1 - 4e-06 27.1 1.6 0.00043 20.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO29682.1 - 7.6e-05 22.7 0.5 0.00096 19.2 0.5 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO29682.1 - 0.00012 22.5 0.7 0.00021 21.7 0.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGO29682.1 - 0.0014 18.8 0.0 0.0017 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO29682.1 - 0.0048 17.4 0.0 0.0069 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO29682.1 - 0.0052 17.0 0.1 0.0088 16.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO29682.1 - 0.0053 17.1 0.1 0.011 16.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO29682.1 - 0.0057 16.4 0.2 0.018 14.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO29682.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGO29682.1 - 0.018 15.1 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGO29682.1 - 0.025 15.0 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EGO29682.1 - 0.031 13.9 0.0 1.2 8.7 0.0 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EGO29682.1 - 0.035 13.9 0.2 0.079 12.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 EGO29682.1 - 0.048 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 EGO29682.1 - 0.063 12.5 0.1 0.23 10.6 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 EGO29682.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Torsin TIP49 PF06068.13 EGO29682.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 EGO29682.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain p450 PF00067.22 EGO29683.1 - 3.1e-62 210.8 0.0 4.2e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SWIRM PF04433.17 EGO29684.1 - 2.1e-32 111.3 0.1 4.4e-31 107.1 0.0 2.5 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGO29684.1 - 1e-20 73.4 8.9 2.2e-20 72.4 8.9 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGO29684.1 - 2e-10 40.7 0.0 3.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGO29684.1 - 1.1e-09 37.9 2.9 1.9e-09 37.2 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EGO29684.1 - 1.4e-09 38.0 0.0 3.9e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Blt1 PF12754.7 EGO29684.1 - 0.094 13.0 0.4 0.22 11.8 0.4 1.5 1 0 0 1 1 1 0 Blt1 N-terminal domain SANT_DAMP1_like PF16282.5 EGO29684.1 - 0.16 12.2 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF4428 PF14471.6 EGO29684.1 - 0.16 11.9 0.9 0.36 10.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) RelB_N PF18506.1 EGO29684.1 - 0.26 11.1 2.0 0.39 10.5 0.5 2.1 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain Chordopox_RPO7 PF05864.12 EGO29684.1 - 0.59 10.4 2.4 3.5 8.0 0.7 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PPR PF01535.20 EGO29685.1 - 2.2e-08 33.8 0.0 0.31 11.4 0.0 5.6 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 EGO29685.1 - 2.5e-07 30.8 0.0 0.75 10.0 0.0 5.1 4 1 1 5 5 5 2 PPR repeat family PPR_long PF17177.4 EGO29685.1 - 9.2e-06 25.2 2.0 0.00012 21.5 0.0 3.4 3 2 2 5 5 5 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGO29685.1 - 0.049 13.7 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO29685.1 - 0.054 13.2 0.4 3.4 7.5 0.0 3.3 4 0 0 4 4 4 0 PPR repeat TPR_14 PF13428.6 EGO29685.1 - 0.062 14.2 1.5 13 6.9 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Mucin15 PF15672.5 EGO29686.1 - 0.81 9.1 5.2 0.39 10.2 2.3 1.8 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 Pkinase PF00069.25 EGO29687.1 - 2e-66 224.1 0.0 3.4e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29687.1 - 1.3e-32 113.2 0.0 2.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO29687.1 - 0.0021 18.0 0.0 0.0067 16.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fungal_KA1 PF16797.5 EGO29687.1 - 0.0026 17.5 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Fungal kinase associated-1 domain zf-C3HC4_3 PF13920.6 EGO29688.1 - 2.1e-11 43.5 5.8 1.4e-09 37.6 1.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO29688.1 - 0.0012 18.6 5.1 0.0012 18.6 5.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGO29688.1 - 0.0017 18.6 6.6 0.0051 17.1 2.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGO29688.1 - 0.0083 16.1 3.2 0.055 13.4 0.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO29688.1 - 0.37 10.9 4.9 6.5 6.9 0.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L27A PF00828.19 EGO29689.1 - 6.1e-21 75.4 0.0 9.2e-21 74.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 EGO29690.1 - 1.2e-25 89.0 0.0 1.5e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGO29690.1 - 3.6e-10 39.1 0.0 5.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MMR_HSR1 PF01926.23 EGO29691.1 - 2.1e-11 43.9 0.0 5e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO29691.1 - 9.7e-06 25.6 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EGO29691.1 - 0.0046 16.5 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EGO29691.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 EGO29691.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EGO29691.1 - 0.035 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 EGO29691.1 - 0.047 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 EGO29691.1 - 0.074 13.6 1.5 0.12 12.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 EGO29691.1 - 0.11 11.6 0.1 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EGO29691.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.18 EGO29691.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 EGO29691.1 - 0.17 11.9 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Dynamin family DUF4551 PF15087.6 EGO29692.1 - 9.4 4.9 5.3 12 4.6 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HLH PF00010.26 EGO29695.1 - 2.2e-07 30.7 0.0 7.1e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.22 EGO29696.1 - 9.6e-13 47.8 0.0 1.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGO29696.1 - 0.12 13.0 0.1 0.24 12.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 6PF2K PF01591.18 EGO29697.1 - 3.1e-60 203.2 0.0 4.9e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGO29697.1 - 8.6e-23 81.0 0.0 1.1e-18 67.7 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGO29697.1 - 0.0008 19.6 0.0 0.0024 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EGO29697.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 EGO29697.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF155 PF02582.14 EGO29698.1 - 6.1e-45 153.5 0.0 9.6e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LSM PF01423.22 EGO29699.1 - 3.6e-16 58.6 0.2 4.4e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain TPT PF03151.16 EGO29700.1 - 1.1e-25 90.6 15.9 1.3e-25 90.3 15.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO29700.1 - 0.097 12.8 30.6 0.081 13.1 10.1 2.3 2 0 0 2 2 2 0 EamA-like transporter family TMEM238 PF15125.6 EGO29700.1 - 0.21 11.8 3.6 0.78 10.0 3.6 2.0 1 0 0 1 1 1 0 TMEM238 protein family DUF563 PF04577.14 EGO29701.1 - 1.8e-08 34.8 0.0 2.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Histone PF00125.24 EGO29702.1 - 1.3e-17 64.4 0.0 1.7e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGO29702.1 - 7.5e-17 60.8 0.3 1.5e-16 59.8 0.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGO29702.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP-synt_10 PF05176.14 EGO29703.1 - 2.4e-62 210.5 0.0 2.9e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Sec23_trunk PF04811.15 EGO29704.1 - 4.3e-70 236.1 0.0 7e-70 235.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGO29704.1 - 2.5e-23 81.9 0.3 5.7e-23 80.7 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGO29704.1 - 3.4e-17 63.0 0.0 9.2e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGO29704.1 - 3.7e-16 58.9 7.5 7.2e-16 58.0 7.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGO29704.1 - 8.1e-10 38.5 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 EGO29704.1 - 4.1e-06 26.8 0.2 4.1e-06 26.8 0.2 2.0 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 EGO29704.1 - 0.0051 16.2 0.6 0.01 15.2 0.6 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain MFS_1 PF07690.16 EGO29705.1 - 7.9e-16 57.9 46.8 1.1e-10 41.0 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PITH PF06201.13 EGO29706.1 - 3.9e-37 127.8 0.0 4.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Transp_cyt_pur PF02133.15 EGO29708.1 - 9.1e-146 486.1 41.6 1.1e-145 485.9 41.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RmlD_sub_bind PF04321.17 EGO29710.1 - 3.9e-52 177.1 0.0 4.7e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGO29710.1 - 1.1e-22 80.7 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO29710.1 - 1.7e-08 34.3 0.0 1.1e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGO29710.1 - 2.7e-05 23.5 0.0 0.0068 15.6 0.0 2.7 2 1 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGO29710.1 - 0.0017 17.6 0.0 0.035 13.3 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.20 EGO29710.1 - 0.0025 17.9 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EGO29710.1 - 0.2 11.2 0.0 0.66 9.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Vps16_C PF04840.12 EGO29713.1 - 1.5e-82 277.2 0.1 2.1e-82 276.8 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EGO29713.1 - 2.5e-80 270.2 0.0 3.3e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 EGO29713.1 - 0.029 14.7 0.0 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RIB43A PF05914.12 EGO29713.1 - 0.061 12.1 0.6 0.098 11.4 0.6 1.2 1 0 0 1 1 1 0 RIB43A DUF4381 PF14316.6 EGO29714.1 - 0.067 13.4 0.0 0.083 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EXS PF03124.14 EGO29715.1 - 8e-32 110.9 8.6 8.9e-32 110.7 8.6 1.0 1 0 0 1 1 1 1 EXS family BTB PF00651.31 EGO29720.1 - 2e-07 31.2 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGO29721.1 - 2.1e-10 40.8 0.0 3.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rotamase_3 PF13616.6 EGO29722.1 - 9.3e-19 68.1 0.4 2.1e-18 66.9 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGO29722.1 - 1.4e-15 58.0 2.7 2e-15 57.5 0.0 2.1 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGO29722.1 - 2.9e-05 24.9 3.0 0.0002 22.2 3.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain PIG-S PF10510.9 EGO29724.1 - 1.5e-115 386.9 5.7 1e-114 384.3 5.7 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein CLTH PF10607.9 EGO29725.1 - 4.6e-33 114.2 0.9 8.3e-33 113.4 0.9 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain HlyIII PF03006.20 EGO29726.1 - 1.1e-57 195.3 18.2 1.4e-57 195.0 18.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 EGO29726.1 - 0.74 9.9 6.5 9 6.5 5.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF962) p450 PF00067.22 EGO29727.1 - 7.2e-33 114.0 0.0 1.5e-32 113.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 BAH PF01426.18 EGO29727.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 BAH domain Cofilin_ADF PF00241.20 EGO29728.1 - 2.9e-26 91.6 0.1 3.3e-26 91.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.25 EGO29729.1 - 6.4e-18 65.1 0.0 7.7e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO29729.1 - 1.2e-07 32.1 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO29729.1 - 8.9e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO29729.1 - 1.2e-05 26.0 0.0 1.7e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO29729.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 EGO29729.1 - 0.044 13.9 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NAC PF01849.18 EGO29730.1 - 7.5e-24 83.5 0.1 1.3e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 NAC domain XPG_I PF00867.18 EGO29731.1 - 8.5e-15 54.9 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGO29731.1 - 5e-08 33.4 0.0 9.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EGO29731.1 - 0.0059 17.2 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 EGO29731.1 - 0.031 14.2 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Coatomer_WDAD PF04053.14 EGO29732.1 - 7.6e-137 457.0 0.0 2.6e-136 455.2 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EGO29732.1 - 5e-112 374.6 0.0 6.8e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGO29732.1 - 2.4e-45 151.6 12.3 5.1e-08 33.5 0.3 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29732.1 - 9.5e-12 45.1 0.1 0.0033 17.7 0.0 5.9 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 EGO29732.1 - 0.00087 19.9 3.4 3 8.9 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Nup160 PF11715.8 EGO29732.1 - 0.096 11.3 2.8 7.1 5.1 0.6 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.20 EGO29732.1 - 0.12 12.2 0.1 0.58 10.0 0.1 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS GHL13 PF14883.6 EGO29733.1 - 0.0015 17.6 0.1 0.0018 17.4 0.1 1.1 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 ArgoMid PF16487.5 EGO29733.1 - 0.05 13.9 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Mid domain of argonaute DUF4235 PF14019.6 EGO29733.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) SPA PF08616.10 EGO29734.1 - 4.6e-30 103.9 0.0 8.1e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EGO29734.1 - 5.9e-21 75.3 0.1 4.7e-16 59.5 0.1 2.5 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EGO29734.1 - 0.00095 18.0 0.0 0.051 12.3 0.0 3.2 4 0 0 4 4 4 1 Transport protein Avl9 NDUFA12 PF05071.16 EGO29739.1 - 2e-08 35.0 0.3 4.2e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PCI PF01399.27 EGO29740.1 - 1.4e-22 80.2 0.3 4.7e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 EGO29740.1 - 3.6e-20 72.2 0.1 3.6e-20 72.2 0.1 2.9 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 EGO29740.1 - 0.15 12.3 2.7 0.36 11.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r1_2 PF00140.20 EGO29740.1 - 0.31 11.1 2.4 0.91 9.6 2.4 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 TPR_16 PF13432.6 EGO29740.1 - 1.1 10.0 10.1 2.6 8.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribophorin_II PF05817.14 EGO29741.1 - 9.4e-31 107.1 0.0 1.2e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TruB_N PF01509.18 EGO29742.1 - 3.6e-43 147.5 0.0 1.1e-42 145.9 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGO29742.1 - 2.4e-05 24.4 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Plavaka PF18759.1 EGO29746.1 - 1.7e-05 24.3 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Myb_DNA-bind_3 PF12776.7 EGO29747.1 - 2e-07 31.9 0.2 2.6e-07 31.5 0.2 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Aldo_ket_red PF00248.21 EGO29749.1 - 4.1e-71 239.6 0.0 4.7e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.24 EGO29750.1 - 6.5e-19 68.0 0.0 1.5e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 EGO29750.1 - 2e-12 47.1 0.2 7.9e-12 45.1 0.5 1.7 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 EGO29750.1 - 2.6e-05 23.7 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO29750.1 - 7.3e-05 22.5 0.2 0.00014 21.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EGO29750.1 - 0.095 13.0 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain hSH3 PF14603.6 EGO29750.1 - 0.16 12.5 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain CUE PF02845.16 EGO29751.1 - 5.5e-05 22.8 0.1 0.00049 19.8 0.1 2.6 1 1 0 1 1 1 1 CUE domain Homeobox_KN PF05920.11 EGO29751.1 - 0.62 10.0 1.9 27 4.8 0.2 2.7 2 0 0 2 2 2 0 Homeobox KN domain ABC_tran PF00005.27 EGO29755.1 - 1.4e-19 71.0 0.6 7.4e-09 36.2 0.1 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO29755.1 - 4e-06 26.9 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO29755.1 - 5.1e-06 26.1 0.8 0.0046 16.4 0.1 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGO29755.1 - 0.0022 18.2 0.0 2.4 8.5 0.0 2.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EGO29755.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EGO29755.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EGO29755.1 - 0.034 14.3 0.0 0.092 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGO29755.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO29755.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EGO29755.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGO29755.1 - 0.072 13.5 0.0 0.29 11.5 0.0 2.0 2 1 1 3 3 3 0 AAA ATPase domain AAA PF00004.29 EGO29755.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGO29755.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lactococcin PF04369.13 EGO29755.1 - 0.09 12.9 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Lactococcin-like family PduV-EutP PF10662.9 EGO29755.1 - 0.1 12.3 0.1 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 EGO29755.1 - 0.12 11.7 0.1 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 EGO29755.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 EGO29755.1 - 0.2 10.2 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGO29755.1 - 0.39 11.2 4.4 0.19 12.2 0.5 2.1 2 0 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.21 EGO29758.1 - 1.9e-70 237.4 0.0 2.2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OB_Dis3 PF17849.1 EGO29758.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) Aldo_ket_red PF00248.21 EGO29759.1 - 1.6e-41 142.5 0.0 9.1e-40 136.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.27 EGO29759.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Oxidored_FMN PF00724.20 EGO29760.1 - 2.2e-26 93.0 0.0 1.7e-25 90.1 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 EGO29761.1 - 6.4e-32 110.6 0.0 1.1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO29761.1 - 1.7e-22 80.2 0.0 4.6e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGO29761.1 - 4.5e-05 23.0 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EGO29761.1 - 6.8e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 KR domain TFIIE_alpha PF02002.17 EGO29762.1 - 2.1e-17 62.9 0.1 4.5e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 EGO29762.1 - 1.4e-06 28.5 0.2 1.4e-06 28.5 0.2 2.5 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha YppF PF14178.6 EGO29762.1 - 0.015 15.2 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 YppF-like protein TF_Zn_Ribbon PF08271.12 EGO29762.1 - 0.035 13.6 0.4 0.078 12.5 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding CbiG_mid PF11761.8 EGO29762.1 - 0.075 13.2 0.2 0.32 11.1 0.0 2.2 3 0 0 3 3 3 0 Cobalamin biosynthesis central region zf_UBZ PF18439.1 EGO29762.1 - 0.21 11.2 0.8 6.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger NmrA PF05368.13 EGO29765.1 - 1.4e-46 158.9 0.0 1.7e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO29765.1 - 3.2e-21 76.1 0.0 4.2e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO29765.1 - 3.7e-07 29.8 0.0 9.4e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO29765.1 - 1e-06 28.0 0.0 2e-06 27.0 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGO29765.1 - 0.0036 17.5 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGO29765.1 - 0.006 16.8 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 EGO29765.1 - 0.0098 15.4 0.1 0.022 14.2 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 EGO29765.1 - 0.022 15.3 0.0 0.067 13.8 0.0 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CodY PF06018.14 EGO29767.1 - 0.063 12.8 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 CodY GAF-like domain LRR_6 PF13516.6 EGO29768.1 - 0.00023 21.0 11.0 0.0032 17.4 0.1 4.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 EGO29768.1 - 2.5 8.7 9.9 49 4.5 2.1 4.6 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_hydro_53 PF07745.13 EGO29769.1 - 6.1e-74 249.0 0.0 7.3e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 EGO29769.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF2207 PF09972.9 EGO29770.1 - 0.0013 17.6 0.2 0.0021 16.9 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 EGO29770.1 - 0.0053 16.4 1.3 0.026 14.2 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) MscS_TM PF12794.7 EGO29770.1 - 0.018 14.0 0.7 0.026 13.4 0.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 LPG_synthase_TM PF03706.13 EGO29770.1 - 0.02 14.5 4.8 0.041 13.4 4.8 1.5 1 1 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Phage_holin_3_6 PF07332.11 EGO29770.1 - 0.034 14.2 3.2 0.099 12.7 1.1 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 EGO29770.1 - 0.048 13.6 3.7 0.1 12.6 0.7 2.5 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Peptidase_C14 PF00656.22 EGO29771.1 - 4.3e-16 59.6 0.0 5.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 EGO29772.1 - 3.2e-31 109.2 0.0 6.7e-31 108.1 0.0 1.5 1 1 0 1 1 1 1 Caspase domain COesterase PF00135.28 EGO29773.1 - 0.013 14.4 0.0 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 Carboxylesterase family LRR_6 PF13516.6 EGO29774.1 - 0.001 18.9 4.3 0.01 15.8 0.0 4.2 6 0 0 6 6 6 1 Leucine Rich repeat TENA_THI-4 PF03070.16 EGO29776.1 - 0.00014 21.7 0.3 0.23 11.2 0.2 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Ser_hydrolase PF06821.13 EGO29776.1 - 0.0083 16.0 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase TMEM219 PF14940.6 EGO29777.1 - 0.28 10.7 1.3 11 5.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane 219 p450 PF00067.22 EGO29778.1 - 1.6e-77 261.2 0.0 2.6e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 EGO29781.1 - 3.3e-22 78.5 0.0 6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO29781.1 - 3.8e-15 55.7 0.0 7.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO29781.1 - 1.2e-09 38.3 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO29781.1 - 1.7e-05 24.9 0.0 4.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO29781.1 - 3.3e-05 24.2 0.0 0.00051 20.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain QIL1 PF15884.5 EGO29781.1 - 0.1 13.2 0.1 6.8 7.4 0.0 2.4 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 ubiquitin PF00240.23 EGO29782.1 - 3.5e-16 58.7 0.0 6e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 EGO29782.1 - 8.4e-08 32.7 8.7 4.4e-07 30.3 3.5 2.2 2 0 0 2 2 2 2 Blt1 N-terminal domain Rad60-SLD PF11976.8 EGO29782.1 - 9.6e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGO29782.1 - 0.046 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ndufs5 PF10200.9 EGO29783.1 - 2e-05 24.8 0.6 2.6e-05 24.4 0.6 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 EGO29783.1 - 0.0038 17.2 1.9 0.0057 16.7 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Defensin_5 PF18251.1 EGO29783.1 - 0.035 14.2 0.4 0.072 13.2 0.4 1.6 1 0 0 1 1 1 0 Fungal defensin Copsin PADR1 PF08063.12 EGO29783.1 - 0.036 13.9 3.1 4.4 7.2 0.9 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain FAT PF02259.23 EGO29783.1 - 0.089 12.0 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 FAT domain DUF769 PF05590.11 EGO29783.1 - 0.094 12.1 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) CHCH PF06747.13 EGO29783.1 - 0.11 12.7 5.5 0.41 10.9 3.4 2.1 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.8 EGO29783.1 - 0.46 10.9 5.8 1.7 9.1 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) G-patch PF01585.23 EGO29784.1 - 9.4e-07 28.6 4.7 1.2e-06 28.3 3.9 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EGO29784.1 - 0.026 14.6 0.8 0.065 13.3 0.8 1.7 1 0 0 1 1 1 0 G-patch domain tRNA_anti-like PF12869.7 EGO29784.1 - 0.095 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA_anti-like UQ_con PF00179.26 EGO29786.1 - 6.1e-54 181.5 0.0 6.8e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGO29786.1 - 0.0053 17.0 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGO29786.1 - 0.014 15.1 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EGO29786.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Nup96 PF12110.8 EGO29788.1 - 2.2e-94 315.8 0.0 3.3e-94 315.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 BUD22 PF09073.10 EGO29788.1 - 7.7 5.7 26.4 13 5.0 26.4 1.2 1 0 0 1 1 1 0 BUD22 PALP PF00291.25 EGO29790.1 - 5.2e-60 203.4 0.1 1.1e-59 202.3 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GRDP-like PF07173.12 EGO29790.1 - 0.033 14.8 0.0 0.092 13.4 0.0 1.7 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Lum_binding PF00677.17 EGO29792.1 - 3.4e-44 148.7 0.1 8.9e-22 76.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain PALP PF00291.25 EGO29793.1 - 1.2e-59 202.1 0.6 2e-59 201.4 0.6 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GRDP-like PF07173.12 EGO29793.1 - 0.0035 18.0 0.0 0.0079 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Pet100 PF09803.9 EGO29794.1 - 8.5e-26 90.3 0.1 1.2e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 Pet100 Pyridoxal_deC PF00282.19 EGO29795.1 - 6.8e-62 209.3 0.0 9.7e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGO29795.1 - 2e-06 27.0 0.0 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V PIG-L PF02585.17 EGO29796.1 - 2.2e-16 60.7 0.0 3e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.10 EGO29797.1 - 0.0001 23.2 0.5 0.00024 22.0 0.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF3455 PF11937.8 EGO29798.1 - 8.6e-22 78.2 0.2 1.2e-21 77.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Man-6-P_recep PF02157.15 EGO29801.1 - 0.094 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DNA_primase_S PF01896.19 EGO29802.1 - 1.4e-55 188.1 0.1 1.8e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF2448 PF10476.9 EGO29802.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) zf-CCHC PF00098.23 EGO29803.1 - 0.0013 18.7 4.1 0.0022 18.0 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle CCDC71L PF15374.6 EGO29803.1 - 6.5 5.9 9.2 0.11 11.7 2.6 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L RVP_2 PF08284.11 EGO29804.1 - 1.3e-05 25.0 0.0 1.4e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO29804.1 - 0.00079 19.9 0.0 0.00093 19.7 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO29804.1 - 0.0011 19.5 0.0 0.0015 19.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Pollen_Ole_e_I PF01190.17 EGO29804.1 - 0.058 13.8 0.0 0.072 13.5 0.0 1.1 1 0 0 1 1 1 0 Pollen proteins Ole e I like ABC_tran PF00005.27 EGO29806.1 - 5.8e-48 162.9 0.0 1.3e-28 100.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO29806.1 - 5.2e-46 157.5 24.8 2.2e-25 89.9 8.4 3.6 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO29806.1 - 1.1e-08 34.8 0.3 0.017 14.6 1.4 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO29806.1 - 0.0003 20.5 1.1 0.24 11.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EGO29806.1 - 0.0014 18.3 0.1 0.78 9.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGO29806.1 - 0.0031 17.8 0.5 1.4 9.1 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO29806.1 - 0.0057 17.0 0.1 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EGO29806.1 - 0.0069 15.5 0.1 2.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 EGO29806.1 - 0.01 16.4 0.5 6 7.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO29806.1 - 0.029 14.1 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGO29806.1 - 0.034 14.3 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ATPase PF06745.13 EGO29806.1 - 0.059 12.7 0.3 8.7 5.6 0.0 2.4 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 EGO29806.1 - 0.11 11.6 1.0 2.5 7.2 0.1 2.8 3 1 0 3 3 3 0 NB-ARC domain FKBP_N_2 PF18023.1 EGO29806.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 BDBT FKBP like N-terminal NACHT PF05729.12 EGO29806.1 - 0.16 11.8 0.7 27 4.7 0.2 2.9 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.9 EGO29806.1 - 0.22 10.7 0.2 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EGO29806.1 - 0.69 9.5 3.2 0.7 9.5 0.5 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Malic_M PF03949.15 EGO29808.1 - 9.6e-90 300.3 0.0 1.3e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGO29808.1 - 1.6e-65 220.3 0.0 3.4e-65 219.2 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain TFIIS_C PF01096.18 EGO29808.1 - 0.23 11.3 0.1 7.9 6.4 0.0 2.8 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) adh_short_C2 PF13561.6 EGO29809.1 - 5.8e-56 189.7 0.0 6.6e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO29809.1 - 4e-52 176.5 0.0 5.7e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO29809.1 - 6.9e-16 58.7 0.1 9.8e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO29809.1 - 2.6e-05 23.8 0.0 7.3e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO29809.1 - 0.0007 19.1 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO29809.1 - 0.0047 16.1 0.1 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain ADH_N PF08240.12 EGO29810.1 - 3.4e-28 97.7 0.6 7.2e-28 96.6 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO29810.1 - 3.2e-23 82.1 0.1 5.3e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO29810.1 - 3.7e-09 36.4 0.2 8.8e-07 28.6 0.2 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGO29810.1 - 6.2e-07 30.5 0.0 1.2e-06 29.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO29810.1 - 0.00053 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 EGO29810.1 - 0.0049 17.5 0.1 0.012 16.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGO29810.1 - 0.0059 16.0 0.1 0.0097 15.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGO29810.1 - 0.0068 17.0 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EGO29810.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EGO29810.1 - 0.043 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.14 EGO29810.1 - 0.047 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.18 EGO29810.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Hydantoinase_A PF01968.18 EGO29810.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase YdfZ PF14001.6 EGO29810.1 - 0.17 12.3 0.6 6.2 7.3 0.0 3.0 3 0 0 3 3 3 0 YdfZ protein Aminotran_4 PF01063.19 EGO29812.1 - 1.8e-30 106.5 0.0 3e-30 105.8 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV Dus PF01207.17 EGO29813.1 - 8.1e-59 199.2 0.0 1e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PdxJ PF03740.13 EGO29813.1 - 0.069 12.2 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ His_biosynth PF00977.21 EGO29813.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein EMP24_GP25L PF01105.24 EGO29814.1 - 1e-38 133.1 0.1 1.8e-38 132.3 0.0 1.4 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 EGO29814.1 - 0.003 17.1 0.1 0.0055 16.2 0.1 1.4 1 0 0 1 1 1 1 Trimerisation motif TRPM_tetra PF16519.5 EGO29814.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM EzrA PF06160.12 EGO29814.1 - 0.052 11.7 0.1 0.054 11.7 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TolA_bind_tri PF16331.5 EGO29814.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation MR_MLE_C PF13378.6 EGO29815.1 - 1.6e-56 191.4 0.0 2e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGO29815.1 - 1.6e-21 76.7 0.0 3.1e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain F-box-like PF12937.7 EGO29816.1 - 7.2e-05 22.6 0.3 0.00018 21.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like Glyco_hydro_61 PF03443.14 EGO29817.1 - 4.1e-64 216.3 0.1 5.3e-64 215.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Amino_oxidase PF01593.24 EGO29818.1 - 1e-25 91.0 0.0 1.2e-25 90.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO29818.1 - 5.9e-10 39.2 0.0 5.9e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO29818.1 - 6.2e-07 29.3 5.2 3.7e-06 26.8 0.0 3.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO29818.1 - 0.023 13.9 0.1 0.39 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO29818.1 - 0.026 13.8 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family MCRA PF06100.11 EGO29818.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 EGO29818.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Plavaka PF18759.1 EGO29822.1 - 1.7e-34 119.5 0.0 2.2e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase SCNM1_acidic PF15805.5 EGO29822.1 - 0.056 13.2 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf_C2H2_ZHX PF18387.1 EGO29822.1 - 0.31 10.7 1.6 0.81 9.4 1.6 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Plavaka PF18759.1 EGO29823.1 - 4.7e-33 114.8 3.8 6.4e-33 114.3 3.8 1.2 1 0 0 1 1 1 1 Plavaka transposase Alpha_kinase PF02816.18 EGO29825.1 - 3.4e-10 40.4 0.0 7.4e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Alpha-kinase family SPC25 PF06703.11 EGO29826.1 - 3e-52 176.7 0.0 3.6e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) ERG2_Sigma1R PF04622.12 EGO29827.1 - 2.1e-93 311.4 0.1 2.5e-93 311.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein p450 PF00067.22 EGO29828.1 - 4e-70 236.9 0.0 4.8e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO29829.1 - 2.5e-65 221.0 0.0 3.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO29830.1 - 3.3e-17 62.4 0.0 3.5e-09 35.9 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 p450 PF00067.22 EGO29831.1 - 2.1e-63 214.7 0.0 3.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Histone PF00125.24 EGO29832.1 - 1.7e-18 67.3 0.0 2.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGO29832.1 - 1.5e-17 63.0 0.8 3e-17 62.1 0.8 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGO29832.1 - 1.2e-06 28.6 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO29833.1 - 6.7e-23 81.5 2.7 9.2e-23 81.0 2.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO29833.1 - 1.6e-05 25.1 0.1 4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGO29833.1 - 0.00027 21.4 0.0 0.00059 20.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.11 EGO29833.1 - 0.11 12.1 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF2282 PF10048.9 EGO29834.1 - 0.0019 18.1 1.4 0.0026 17.7 1.4 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2282) RR_TM4-6 PF06459.12 EGO29835.1 - 1.3 8.8 4.0 1.7 8.4 4.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 EGO29835.1 - 2.8 6.7 8.6 3.1 6.6 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 EGO29835.1 - 3.3 7.6 17.6 3.7 7.4 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EGO29835.1 - 3.6 7.5 9.5 4.5 7.2 9.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOG2 PF10428.9 EGO29835.1 - 6.7 5.8 20.0 8.8 5.4 20.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Histone PF00125.24 EGO29836.1 - 3.6e-24 85.6 3.0 4.8e-24 85.2 3.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO29836.1 - 7.4e-05 23.0 0.1 7.4e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGO29836.1 - 0.00035 21.0 0.0 0.00069 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 EGO29837.1 - 1.1e-18 67.9 0.0 1.3e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGO29837.1 - 2.1e-15 56.1 0.3 2.1e-15 56.1 0.3 2.1 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGO29837.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fungal_trans PF04082.18 EGO29838.1 - 5.5e-08 32.2 0.0 2.6e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO29838.1 - 0.0035 17.4 7.6 0.0072 16.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7TMR-DISMED2 PF07696.11 EGO29838.1 - 0.043 13.9 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 F-box PF00646.33 EGO29839.1 - 1.3e-06 28.1 0.3 2.6e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO29839.1 - 3.4e-06 26.8 0.9 7e-06 25.9 0.9 1.5 1 0 0 1 1 1 1 F-box-like GRAB PF10375.9 EGO29840.1 - 7.8e-08 31.9 1.7 1.8e-07 30.8 1.7 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain PKHD_C PF18331.1 EGO29840.1 - 0.005 16.9 0.2 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain KLRAQ PF10205.9 EGO29840.1 - 0.012 15.8 3.6 0.012 15.8 3.6 4.0 1 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein GRIP PF01465.20 EGO29840.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 GRIP domain PspA_IM30 PF04012.12 EGO29840.1 - 0.35 10.4 31.9 0.23 11.0 3.9 2.6 1 1 0 2 2 2 0 PspA/IM30 family DUF1664 PF07889.12 EGO29840.1 - 0.75 9.9 10.4 4.4 7.4 0.4 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) LPP PF04728.13 EGO29840.1 - 5.1 7.6 7.0 1.5 9.3 0.9 3.1 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 EGO29840.1 - 6.7 6.7 8.7 2.7 8.1 3.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HECT_2 PF09814.9 EGO29841.1 - 3.3e-57 194.1 0.0 4.7e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 EGO29841.1 - 0.033 14.4 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly APG17 PF04108.12 EGO29842.1 - 0.06 12.5 0.2 0.058 12.5 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 WD40 PF00400.32 EGO29843.1 - 7.6e-12 45.6 7.4 0.00093 20.0 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29843.1 - 1.4e-06 28.5 0.6 0.1 12.9 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain 2-oxoacid_dh PF00198.23 EGO29844.1 - 1.7e-81 273.1 0.1 2.3e-81 272.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGO29844.1 - 1.4e-18 66.5 2.3 2.8e-18 65.5 2.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGO29844.1 - 0.00064 19.5 0.6 0.0015 18.3 0.5 1.7 1 1 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.19 EGO29844.1 - 0.026 14.4 0.3 0.062 13.2 0.3 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.6 EGO29844.1 - 0.045 14.5 0.5 6.5 7.5 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein LPMO_10 PF03067.15 EGO29845.1 - 4.8e-12 46.9 0.4 7e-12 46.4 0.4 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Rabaptin PF03528.15 EGO29845.1 - 0.0026 16.5 0.0 0.0034 16.1 0.0 1.0 1 0 0 1 1 1 1 Rabaptin Homoserine_dh PF00742.19 EGO29848.1 - 1.2e-47 162.0 0.0 1.7e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGO29848.1 - 4.6e-18 66.0 0.0 9.8e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RNA_pol_3_Rpc31 PF11705.8 EGO29850.1 - 8e-24 85.1 9.4 1.1e-23 84.7 9.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Rop-like PF05082.13 EGO29850.1 - 0.094 12.5 0.5 0.22 11.3 0.5 1.5 1 0 0 1 1 1 0 Rop-like RRM_1 PF00076.22 EGO29851.1 - 4.2e-14 52.1 0.0 6.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGO29851.1 - 1.1e-07 32.2 0.6 1.1e-07 32.2 0.6 2.6 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EGO29851.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif PPTA PF01239.22 EGO29852.1 - 6.3e-45 149.7 17.9 6.2e-10 38.5 0.6 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Phage_holin_2_1 PF04971.12 EGO29853.1 - 0.064 13.3 0.4 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S PCMT PF01135.19 EGO29855.1 - 5.9e-73 245.1 0.1 7e-73 244.8 0.1 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGO29855.1 - 1.3e-07 31.5 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO29855.1 - 5e-06 27.1 0.0 2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO29855.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGO29855.1 - 1.4e-05 25.1 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO29855.1 - 0.00037 21.1 0.0 0.00078 20.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGO29855.1 - 0.00053 19.5 0.0 0.0047 16.3 0.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EGO29855.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGO29855.1 - 0.0048 16.5 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGO29855.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EGO29855.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_5 PF13202.6 EGO29855.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 EGO29855.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 EF hand GCD14 PF08704.10 EGO29855.1 - 0.097 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit EF-hand_6 PF13405.6 EGO29855.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Mem_trans PF03547.18 EGO29856.1 - 1.3e-30 106.0 7.2 1.1e-28 99.8 0.2 2.5 2 1 0 2 2 2 2 Membrane transport protein DUF4750 PF15938.5 EGO29856.1 - 0.019 14.6 1.7 0.079 12.6 1.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) MFS_5 PF05631.14 EGO29857.1 - 9.3e-76 255.0 3.8 1.4e-75 254.4 3.8 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGO29857.1 - 2.7e-16 59.4 26.9 2.7e-16 59.4 26.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF981 PF06168.11 EGO29857.1 - 0.023 14.6 0.6 0.023 14.6 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF981) Glyco_transf_20 PF00982.21 EGO29858.1 - 4.1e-141 470.9 0.0 3.7e-140 467.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGO29858.1 - 1.1e-65 221.1 0.0 2.2e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Gpi1 PF05024.15 EGO29862.1 - 1.7e-63 214.1 7.8 3.2e-63 213.2 7.8 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DAO PF01266.24 EGO29863.1 - 2.9e-24 86.3 0.1 3.7e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO29863.1 - 0.042 14.1 0.6 0.68 10.2 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_transf_24 PF18404.1 EGO29865.1 - 3e-143 476.1 2.5 4e-143 475.6 2.5 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGO29865.1 - 4.1e-59 200.6 0.0 1.3e-58 199.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EGO29865.1 - 1.4e-43 149.0 0.0 2.5e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGO29865.1 - 3.9e-41 139.6 0.0 2.1e-40 137.2 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 EGO29865.1 - 1.2e-29 103.7 0.0 8.1e-26 91.3 0.0 4.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EGO29865.1 - 5.6e-24 84.6 0.0 4.9e-23 81.5 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EGO29865.1 - 2e-05 24.3 0.1 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 E1-E2_ATPase PF00122.20 EGO29866.1 - 4.4e-48 163.2 0.0 4.4e-48 163.2 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGO29866.1 - 4.7e-18 66.2 3.2 1.5e-17 64.6 3.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO29866.1 - 1.4e-11 43.9 0.0 3.3e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO29866.1 - 0.00027 20.8 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO29866.1 - 0.0049 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) zf-MYND PF01753.18 EGO29869.1 - 1.9e-06 27.8 4.8 3.3e-06 27.1 4.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO29869.1 - 0.0084 16.4 0.7 0.016 15.5 0.7 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Bacteriocin_II PF01721.18 EGO29869.1 - 0.44 10.7 1.9 0.78 9.9 1.9 1.3 1 0 0 1 1 1 0 Class II bacteriocin Cnd3 PF12719.7 EGO29870.1 - 1.6e-86 290.2 1.6 6.9e-86 288.1 0.3 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGO29870.1 - 1.8e-07 31.4 7.7 2.6e-06 27.7 0.5 4.4 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EGO29870.1 - 1.3e-06 28.1 2.3 8.6 6.9 0.1 5.6 5 0 0 5 5 5 3 HEAT repeat RTP1_C1 PF10363.9 EGO29870.1 - 0.00044 20.4 0.1 0.0084 16.3 0.0 3.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGO29870.1 - 0.0039 17.7 3.1 1 9.9 0.2 4.6 5 0 0 5 5 5 1 HEAT-like repeat RIX1 PF08167.12 EGO29870.1 - 0.027 14.2 0.0 0.84 9.3 0.0 2.8 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis API5 PF05918.11 EGO29870.1 - 0.052 12.4 0.1 0.15 10.8 0.1 1.8 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ig_J_chain PF15097.6 EGO29870.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin J chain HasA PF06438.12 EGO29874.1 - 0.098 12.3 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Heme-binding protein A (HasA) Sec_GG PF07549.14 EGO29876.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif HNH_2 PF13391.6 EGO29879.1 - 0.00019 21.5 0.0 0.00044 20.3 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 EGO29881.1 - 2.2e-72 243.6 0.0 3.8e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO29881.1 - 3.9e-41 141.0 0.0 6.9e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGO29881.1 - 1.2e-37 127.9 3.5 4.3e-19 68.4 0.4 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGO29881.1 - 6.2e-07 29.0 0.0 2.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGO29881.1 - 0.007 15.4 0.3 0.018 14.0 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain DUF4520 PF15016.6 EGO29881.1 - 0.012 15.6 0.1 0.048 13.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Kdo PF06293.14 EGO29881.1 - 0.056 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thaumatin PF00314.17 EGO29882.1 - 2.1e-71 240.0 15.7 2.4e-71 239.8 15.7 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EGO29882.1 - 0.025 13.9 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta-1,3-glucanase adh_short PF00106.25 EGO29883.1 - 4.5e-27 94.8 0.0 7.3e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO29883.1 - 3.8e-18 65.9 0.3 6.3e-18 65.2 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO29883.1 - 6.2e-07 29.5 0.0 8.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO29883.1 - 5.1e-05 23.2 0.3 9e-05 22.4 0.3 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO29883.1 - 0.0029 17.1 0.3 0.0059 16.1 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO29883.1 - 0.054 12.7 0.1 0.1 11.8 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO29883.1 - 0.061 12.7 0.1 0.11 11.9 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGO29883.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF4668 PF15701.5 EGO29884.1 - 1.6 8.5 5.9 2 8.2 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4668) BatA PF07584.11 EGO29884.1 - 2.7 8.4 4.9 27 5.2 0.2 3.1 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal RabGAP-TBC PF00566.18 EGO29887.1 - 1e-17 64.5 0.0 1.7e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FlgN PF05130.12 EGO29888.1 - 0.00041 20.9 3.6 0.0012 19.3 0.3 3.1 3 1 1 4 4 4 1 FlgN protein NPV_P10 PF05531.12 EGO29888.1 - 0.0024 18.3 4.3 1.7 9.2 0.1 4.6 3 1 0 4 4 4 1 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 EGO29888.1 - 0.0033 17.6 0.8 0.19 12.0 0.1 3.0 2 0 0 2 2 2 1 Flagellar FliJ protein DUF16 PF01519.16 EGO29888.1 - 0.013 16.0 0.8 23 5.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function DUF16 Prefoldin PF02996.17 EGO29888.1 - 0.015 15.2 5.8 0.044 13.7 0.3 3.6 4 0 0 4 4 4 0 Prefoldin subunit Sec5 PF15469.6 EGO29888.1 - 0.032 14.1 0.2 0.76 9.6 0.1 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 SesA PF17107.5 EGO29888.1 - 0.033 14.4 2.6 0.31 11.2 0.2 3.2 2 1 2 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Tmemb_cc2 PF10267.9 EGO29888.1 - 0.043 13.0 0.7 0.71 8.9 0.2 2.5 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein SKA2 PF16740.5 EGO29888.1 - 0.049 13.4 6.8 1.6 8.6 0.0 3.8 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 XhlA PF10779.9 EGO29888.1 - 0.058 13.6 4.1 0.3 11.3 2.9 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF5063 PF16702.5 EGO29888.1 - 0.076 13.4 0.4 2.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) MscS_TM PF12794.7 EGO29888.1 - 0.17 10.7 3.4 6.3 5.5 1.0 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 FliD_C PF07195.12 EGO29888.1 - 0.32 10.4 4.0 7.6 5.9 0.5 3.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fzo_mitofusin PF04799.13 EGO29888.1 - 0.84 9.2 3.1 9.9 5.7 0.1 2.9 2 1 1 3 3 3 0 fzo-like conserved region Fib_alpha PF08702.10 EGO29888.1 - 2.9 8.1 4.8 22 5.2 0.6 3.3 4 0 0 4 4 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EGO29888.1 - 6.1 7.5 6.3 50 4.6 0.2 3.7 4 0 0 4 4 3 0 SlyX Glutaredoxin2_C PF04399.13 EGO29888.1 - 8 6.3 8.3 5.4 6.9 0.1 3.9 5 0 0 5 5 5 0 Glutaredoxin 2, C terminal domain Med9 PF07544.13 EGO29890.1 - 0.033 14.3 0.7 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 T7SS_ESX_EspC PF10824.8 EGO29890.1 - 0.034 14.6 1.9 1.8 9.1 0.0 3.1 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Seryl_tRNA_N PF02403.22 EGO29890.1 - 0.037 14.3 2.7 5.2 7.4 0.2 2.6 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 EGO29890.1 - 0.048 13.2 1.1 0.088 12.4 1.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4706 PF15797.5 EGO29890.1 - 0.061 13.9 0.6 0.26 11.8 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4706) CENP-F_leu_zip PF10473.9 EGO29890.1 - 0.1 12.6 2.5 1.3 9.0 0.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 EGO29890.1 - 0.12 12.4 3.4 0.27 11.2 0.1 2.6 3 0 0 3 3 2 0 Laminin Domain II Flg_hook PF02120.16 EGO29890.1 - 0.13 12.1 0.9 0.27 11.2 0.9 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK YkyA PF10368.9 EGO29890.1 - 0.14 11.8 6.3 0.091 12.4 0.9 2.7 2 1 0 3 3 3 0 Putative cell-wall binding lipoprotein DUF4061 PF13270.6 EGO29890.1 - 0.17 12.2 1.6 7.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DUF3685 PF12452.8 EGO29890.1 - 0.18 11.5 2.5 0.095 12.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) DASH_Dam1 PF08653.10 EGO29890.1 - 0.23 11.3 1.1 17 5.3 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prefoldin_2 PF01920.20 EGO29890.1 - 0.24 11.4 1.4 6.7 6.7 0.1 3.2 3 1 0 3 3 3 0 Prefoldin subunit Lectin_N PF03954.14 EGO29890.1 - 0.4 10.4 3.2 0.72 9.6 0.6 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Prefoldin PF02996.17 EGO29890.1 - 0.81 9.6 3.4 3 7.8 0.1 2.9 3 1 0 3 3 3 0 Prefoldin subunit MscS_porin PF12795.7 EGO29890.1 - 0.88 9.1 13.5 5 6.6 0.9 2.7 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Jnk-SapK_ap_N PF09744.9 EGO29890.1 - 0.97 9.6 3.6 10 6.3 0.8 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GAS PF13851.6 EGO29890.1 - 0.99 8.7 4.8 12 5.2 2.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.18 EGO29890.1 - 1 9.2 6.2 0.52 10.2 0.6 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF4200 PF13863.6 EGO29890.1 - 1.1 9.7 6.4 0.93 9.9 0.8 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Mod_r PF07200.13 EGO29890.1 - 1.6 8.8 5.6 1.5 8.9 1.0 2.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CdvA PF18822.1 EGO29890.1 - 2 8.3 7.7 0.83 9.5 1.1 2.9 3 1 1 4 4 4 0 CdvA-like coiled-coil domain Snapin_Pallidin PF14712.6 EGO29890.1 - 2.2 8.7 7.4 13 6.3 1.9 3.3 2 2 1 3 3 3 0 Snapin/Pallidin Aldedh PF00171.22 EGO29891.1 - 1.1e-81 274.7 0.0 1.4e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAM33 PF02330.16 EGO29894.1 - 5.8e-72 242.1 3.9 6.9e-72 241.8 3.9 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein NucS PF01939.16 EGO29897.1 - 0.0004 19.8 0.0 0.00056 19.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease NucS HSDR_N PF04313.14 EGO29897.1 - 0.034 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) pPIWI_RE_Z PF18155.1 EGO29898.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 1 1 2 2 2 0 pPIWI RE three-gene island domain Z Glyco_hydro_cc PF11790.8 EGO29899.1 - 3.5e-35 121.7 0.1 6e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RasGAP PF00616.19 EGO29899.1 - 7.4e-25 87.9 0.0 9.8e-19 67.9 0.1 2.2 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGO29899.1 - 1.6e-08 34.8 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Dymeclin PF09742.9 EGO29899.1 - 0.075 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Zn_clus PF00172.18 EGO29900.1 - 0.0039 17.3 13.1 0.0058 16.7 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.20 EGO29907.1 - 8.5e-64 216.0 0.0 1.1e-63 215.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGO29907.1 - 0.00037 19.7 0.1 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.20 EGO29908.1 - 1.9e-52 178.6 0.0 2.5e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGO29908.1 - 0.01 15.0 0.6 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) CNH PF00780.22 EGO29910.1 - 1.6e-14 54.2 0.0 2.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain CBS PF00571.28 EGO29911.1 - 7.3e-13 48.8 0.0 0.071 13.6 0.0 4.4 4 0 0 4 4 4 4 CBS domain Cys_Met_Meta_PP PF01053.20 EGO29912.1 - 1.5e-20 73.1 0.0 2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGO29912.1 - 0.00029 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Amidase PF01425.21 EGO29913.1 - 8.3e-106 354.6 0.0 9.7e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Perilipin PF03036.16 EGO29915.1 - 2.1e-09 36.9 13.1 2e-07 30.4 0.1 3.6 1 1 1 3 3 3 2 Perilipin family Apolipoprotein PF01442.18 EGO29915.1 - 0.00037 20.4 6.0 0.0015 18.4 5.6 2.1 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 EGO29915.1 - 0.015 13.3 7.1 0.019 12.9 7.1 1.1 1 0 0 1 1 1 0 Prominin DUF4726 PF15855.5 EGO29915.1 - 0.086 13.1 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Baculo_PEP_C PF04513.12 EGO29915.1 - 0.1 12.7 12.3 0.17 11.9 1.7 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Carbpep_Y_N PF05388.11 EGO29915.1 - 0.13 12.8 4.6 0.37 11.3 1.3 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide REF PF05755.12 EGO29915.1 - 0.18 11.6 5.0 1 9.1 0.5 2.6 2 1 1 3 3 3 0 Rubber elongation factor protein (REF) YtxH PF12732.7 EGO29915.1 - 0.27 11.8 4.5 6.5 7.4 0.4 3.3 3 1 0 3 3 3 0 YtxH-like protein Grg1 PF11034.8 EGO29915.1 - 0.36 11.1 3.1 20 5.5 0.1 2.8 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 ApoLp-III PF07464.11 EGO29915.1 - 1.2 9.2 11.9 8.2 6.5 9.8 2.7 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HSBP1 PF06825.12 EGO29915.1 - 1.6 8.6 5.0 7.1 6.6 0.1 3.6 3 1 1 4 4 4 0 Heat shock factor binding protein 1 HAUS-augmin3 PF14932.6 EGO29915.1 - 8.8 5.8 11.8 5.5 6.5 5.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Vps39_2 PF10367.9 EGO29916.1 - 3.8e-10 40.2 0.4 2.3e-09 37.6 0.0 2.6 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EGO29916.1 - 0.00014 22.1 2.0 0.0091 16.3 0.0 3.1 2 1 1 3 3 3 2 Vacuolar sorting protein 39 domain 1 MscS_TM PF12794.7 EGO29917.1 - 0.0069 15.3 0.3 0.011 14.6 0.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 DUF308 PF03729.13 EGO29917.1 - 0.046 14.1 4.3 0.088 13.1 1.2 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) LPG_synthase_TM PF03706.13 EGO29917.1 - 0.047 13.2 2.9 0.079 12.5 2.9 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region MMS19_C PF12460.8 EGO29917.1 - 0.097 11.8 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal RseC_MucC PF04246.12 EGO29917.1 - 0.15 12.0 3.0 0.58 10.1 1.4 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1206 PF06724.11 EGO29917.1 - 1.1 9.4 4.4 18 5.5 0.8 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1206) Glyco_hydro_92 PF07971.12 EGO29920.1 - 9.1e-129 430.4 2.2 1.3e-128 429.9 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGO29920.1 - 9e-41 140.3 0.1 1.7e-40 139.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain NACHT PF05729.12 EGO29922.1 - 2.3e-09 37.4 0.0 4.7e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO29922.1 - 1.7e-06 28.5 0.0 4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGO29922.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGO29922.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGO29922.1 - 0.011 16.1 0.1 0.041 14.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGO29922.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EGO29922.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EGO29922.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO29922.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO29922.1 - 0.1 13.1 0.1 2.4 8.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGO29922.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase PARP PF00644.20 EGO29924.1 - 3.9e-09 36.4 1.1 4.5e-08 32.9 0.1 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain SNF2_N PF00176.23 EGO29925.1 - 8.3e-67 225.4 1.4 1.5e-66 224.5 1.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EGO29925.1 - 3.4e-48 163.4 18.1 3.4e-48 163.4 18.1 1.9 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 EGO29925.1 - 5.4e-16 58.9 0.0 1.2e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO29925.1 - 2.2e-07 31.0 0.0 5.9e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO29925.1 - 2.1e-05 23.8 0.8 0.00028 20.2 0.0 2.8 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 EGO29925.1 - 0.046 14.3 0.2 0.046 14.3 0.2 2.6 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 MAPEG PF01124.18 EGO29926.1 - 1.1e-14 54.4 0.5 1.3e-14 54.2 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Ion_trans_2 PF07885.16 EGO29926.1 - 0.002 18.1 1.2 0.04 13.9 0.1 2.2 2 0 0 2 2 2 1 Ion channel DASH_Dam1 PF08653.10 EGO29927.1 - 0.024 14.4 0.1 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF4519 PF15012.6 EGO29927.1 - 0.03 14.5 2.4 0.058 13.6 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Med3 PF11593.8 EGO29927.1 - 3.4 6.7 8.1 4.4 6.4 8.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cnd3 PF12719.7 EGO29928.1 - 1.5e-81 273.9 4.9 3.3e-81 272.7 3.1 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGO29928.1 - 0.0035 17.7 5.8 0.0079 16.6 0.2 3.5 3 1 0 3 3 3 1 HEAT repeats IFRD PF05004.13 EGO29928.1 - 0.0062 15.7 5.5 0.89 8.6 0.9 3.1 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 EGO29928.1 - 0.0074 16.5 4.0 2.1 8.8 0.4 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EGO29928.1 - 0.0074 16.8 1.2 9.8 6.8 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 EGO29928.1 - 0.016 15.3 1.2 0.26 11.3 0.2 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EGO29928.1 - 0.039 14.3 0.5 4 7.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 EGO29928.1 - 0.083 13.1 0.3 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5486 PF17588.2 EGO29928.1 - 0.27 11.2 0.5 0.59 10.1 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Sec23_trunk PF04811.15 EGO29930.1 - 1.9e-74 250.3 0.0 2.8e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGO29930.1 - 2.8e-30 104.9 0.2 5.9e-30 103.9 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGO29930.1 - 5.9e-26 90.3 0.1 1.4e-25 89.1 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGO29930.1 - 2e-15 56.5 7.0 3.8e-15 55.7 7.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGO29930.1 - 6.6e-14 51.6 0.0 3e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGO29930.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OPT PF03169.15 EGO29931.1 - 8e-136 454.2 48.7 9.1e-136 454.0 48.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3611 PF12263.8 EGO29931.1 - 9.5 6.1 14.2 0.022 14.7 2.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) E1-E2_ATPase PF00122.20 EGO29932.1 - 6.4e-24 84.5 0.3 1.5e-23 83.3 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGO29932.1 - 3.3e-15 57.0 0.0 4.5e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO29932.1 - 6.9e-05 22.9 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO29932.1 - 0.029 14.1 0.0 0.075 12.8 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO29932.1 - 0.038 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus RNA_pol_N PF01194.17 EGO29933.1 - 1.9e-32 111.4 0.5 2.2e-32 111.1 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EGO29933.1 - 0.058 13.7 0.1 0.072 13.4 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mu-like_Com PF10122.9 EGO29933.1 - 0.072 12.6 0.8 0.43 10.1 0.8 2.0 1 1 0 1 1 1 0 Mu-like prophage protein Com DUF2087 PF09860.9 EGO29933.1 - 0.1 12.7 0.4 0.13 12.5 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) PIP5K PF01504.18 EGO29934.1 - 3.2e-102 341.4 0.0 6.6e-102 340.4 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_C50 PF03568.17 EGO29936.1 - 4e-145 483.9 0.0 8.2e-145 482.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 EGO29936.1 - 9.1e-05 22.7 16.1 5.4 7.4 1.2 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat CHAT PF12770.7 EGO29936.1 - 0.0007 19.1 0.1 0.07 12.5 0.0 3.2 3 0 0 3 3 3 1 CHAT domain TPR_2 PF07719.17 EGO29936.1 - 0.00077 19.4 8.2 19 5.6 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO29936.1 - 0.0012 18.9 0.1 0.84 10.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO29936.1 - 0.012 15.4 7.5 0.28 11.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO29936.1 - 2 8.6 6.0 12 6.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_33 PF13592.6 EGO29937.1 - 0.013 15.1 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.6 EGO29937.1 - 0.061 13.9 0.4 7.4 7.3 0.1 2.2 1 1 1 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.6 EGO29937.1 - 0.11 12.7 0.7 0.57 10.4 0.2 2.1 2 0 0 2 2 2 0 HTH-like domain Orthopox_A5L PF06193.11 EGO29939.1 - 0.0081 15.6 0.3 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like COesterase PF00135.28 EGO29940.1 - 7.9e-77 259.3 0.7 1.9e-76 258.0 0.7 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO29940.1 - 2.5e-08 34.0 0.5 1.2e-07 31.8 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO29940.1 - 0.022 14.2 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-CCHC_3 PF13917.6 EGO29945.1 - 2.2e-05 24.3 1.7 2.2e-05 24.3 1.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO29945.1 - 5.1e-05 23.1 5.3 6.8e-05 22.8 5.3 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO29945.1 - 0.0057 16.1 0.9 0.0091 15.5 0.9 1.5 1 1 0 1 1 1 1 Copper fist DNA binding domain PIP49_C PF12260.8 EGO29948.1 - 0.029 14.0 0.1 0.047 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 zf-CCHC PF00098.23 EGO29950.1 - 0.00034 20.6 1.5 0.00034 20.6 1.5 1.7 2 0 0 2 2 2 1 Zinc knuckle SPAN-X PF07458.12 EGO29950.1 - 0.25 11.8 2.8 0.68 10.4 0.2 2.3 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome RVP_2 PF08284.11 EGO29951.1 - 6.6e-05 22.7 0.1 7.8e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO29951.1 - 0.0023 18.5 0.0 0.0058 17.2 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO29951.1 - 0.0056 17.3 0.0 0.0078 16.8 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease Sec_GG PF07549.14 EGO29953.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Retrotrans_gag PF03732.17 EGO29954.1 - 2e-07 31.2 1.3 3.2e-07 30.5 0.4 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein Arc_C PF18162.1 EGO29955.1 - 0.074 12.9 0.0 0.33 10.8 0.0 2.2 1 1 1 2 2 2 0 Arc C-lobe OPT PF03169.15 EGO29956.1 - 1.5e-143 479.7 46.1 1.7e-143 479.5 46.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLATT_1 PF18181.1 EGO29956.1 - 2.8 7.9 6.0 0.88 9.5 0.0 3.0 2 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2207 PF09972.9 EGO29956.1 - 3.7 6.2 5.7 3.9 6.1 0.9 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Methyltransf_31 PF13847.6 EGO29958.1 - 3.9e-24 85.2 0.0 6.5e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO29958.1 - 2e-20 73.3 0.0 5.2e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO29958.1 - 4.5e-18 65.7 0.0 1.4e-17 64.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO29958.1 - 1.6e-11 44.8 0.0 3.6e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO29958.1 - 3.8e-11 42.8 0.0 8.3e-11 41.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO29958.1 - 1.4e-09 38.0 0.0 2.7e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGO29958.1 - 4.1e-08 33.0 0.1 6.5e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Rhodanese PF00581.20 EGO29958.1 - 1.6e-07 31.8 0.0 6.4e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 Rhodanese-like domain PCMT PF01135.19 EGO29958.1 - 7.9e-05 22.5 0.0 0.00019 21.2 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EGO29958.1 - 9.1e-05 21.8 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EGO29958.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 EGO29958.1 - 0.0027 16.3 0.0 0.0049 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 EGO29958.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 EGO29958.1 - 0.052 14.6 0.0 0.41 11.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.15 EGO29958.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase DOT1 PF08123.13 EGO29958.1 - 0.085 12.4 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 UPF0020 PF01170.18 EGO29958.1 - 0.098 12.3 0.0 0.39 10.4 0.0 1.9 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 EGO29958.1 - 0.16 11.5 0.0 2.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase HMG_box PF00505.19 EGO29960.1 - 2.8e-11 43.7 0.2 6.7e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO29960.1 - 0.00083 19.9 0.2 0.0027 18.3 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain zf-MYND PF01753.18 EGO29965.1 - 7.7e-11 41.9 14.0 1.7e-10 40.8 14.0 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EGO29965.1 - 0.31 11.2 7.6 0.67 10.1 7.6 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 EGO29965.1 - 4.5 7.2 8.4 9.5 6.2 8.4 1.6 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 EGO29965.1 - 7.5 6.9 13.7 23 5.4 13.7 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding COesterase PF00135.28 EGO29967.1 - 1.5e-64 218.7 1.6 1.6e-63 215.3 1.6 2.0 1 1 0 1 1 1 1 Carboxylesterase family Cation_ATPase_C PF00689.21 EGO29969.1 - 0.14 11.9 13.2 2.1 8.0 8.0 2.3 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Retrotrans_gag PF03732.17 EGO29972.1 - 3.2e-06 27.3 0.4 7.6e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein Acyltransf_C PF16076.5 EGO29973.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase C-terminus Plavaka PF18759.1 EGO29974.1 - 1.8e-131 438.2 0.0 2.3e-131 437.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 EGO29974.1 - 0.072 14.0 5.4 0.049 14.5 2.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger TRAP-gamma PF07074.12 EGO29976.1 - 0.053 13.1 3.0 0.061 12.9 0.1 2.1 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) HhH-GPD PF00730.25 EGO29978.1 - 2.6e-11 43.9 0.0 7.6e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGO29978.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PEP_hydrolase PF09370.10 EGO29978.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like HMG_box PF00505.19 EGO29982.1 - 1.6e-09 38.0 8.6 4.3e-08 33.4 8.6 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO29982.1 - 3.7e-08 33.9 2.2 9.1e-08 32.6 2.2 1.6 1 0 0 1 1 1 1 HMG-box domain DUF2672 PF10878.8 EGO29982.1 - 0.2 11.6 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Aldo_ket_red PF00248.21 EGO29983.1 - 1.6e-44 152.3 0.0 2.7e-38 131.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Glycophorin_A PF01102.18 EGO29984.1 - 0.12 12.6 0.1 0.14 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycophorin A AA_permease_2 PF13520.6 EGO29985.1 - 3.5e-40 138.1 12.5 3.5e-40 138.1 12.5 1.3 1 1 0 1 1 1 1 Amino acid permease Na_Ca_ex PF01699.24 EGO29985.1 - 1.3 9.0 9.4 0.15 12.0 1.2 2.2 2 0 0 2 2 2 0 Sodium/calcium exchanger protein DUF5134 PF17197.4 EGO29985.1 - 5.7 6.8 7.6 1.4 8.8 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) WD40 PF00400.32 EGO29986.1 - 6.6e-13 48.9 9.6 0.00081 20.2 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO29986.1 - 1.3e-05 25.4 0.0 0.22 11.8 0.0 4.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C14 PF00656.22 EGO29987.1 - 2.2e-08 34.4 0.0 1.4e-05 25.1 0.0 2.4 1 1 1 2 2 2 2 Caspase domain adh_short PF00106.25 EGO29988.1 - 3.8e-11 42.8 0.0 1.5e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO29988.1 - 8.9e-08 32.0 0.0 1.3e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO29988.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain UPF0220 PF05255.11 EGO29989.1 - 1.1e-53 181.2 0.1 1.3e-53 180.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Peptidase_M13_N PF05649.13 EGO29990.1 - 0.2 11.3 0.1 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 Thaumatin PF00314.17 EGO29991.1 - 2.2e-12 47.1 11.8 3e-12 46.6 11.8 1.2 1 0 0 1 1 1 1 Thaumatin family rve PF00665.26 EGO29992.1 - 3.3e-05 24.0 0.1 0.00042 20.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO29992.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve PF00665.26 EGO29994.1 - 3.3e-05 24.0 0.1 0.00042 20.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 EGO29994.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Thaumatin PF00314.17 EGO29996.1 - 2.8e-12 46.7 11.5 3.9e-12 46.3 11.5 1.3 1 0 0 1 1 1 1 Thaumatin family Costars PF14705.6 EGO29997.1 - 2.9e-15 56.2 0.1 4.1e-15 55.7 0.1 1.3 1 1 0 1 1 1 1 Costars RelB PF04221.12 EGO29997.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RelB antitoxin tRNA-synt_1d PF00750.19 EGO30001.1 - 1.4e-96 323.5 2.8 1.9e-96 323.0 2.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGO30001.1 - 5.4e-18 65.3 0.0 1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Syndecan PF01034.20 EGO30002.1 - 0.0055 16.6 0.6 0.009 15.9 0.6 1.2 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 EGO30002.1 - 0.095 13.6 0.1 0.17 12.8 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2613 PF11021.8 EGO30002.1 - 0.71 10.0 0.0 0.71 10.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) MGC-24 PF05283.11 EGO30002.1 - 1.6 9.1 9.2 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 EGO30003.1 - 0.025 15.4 0.0 0.041 14.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EGO30003.1 - 0.06 13.3 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5554 PF17709.1 EGO30003.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5554) CC2-LZ PF16516.5 EGO30005.1 - 0.041 14.3 1.5 0.09 13.1 1.5 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MAP65_ASE1 PF03999.12 EGO30005.1 - 0.093 11.4 0.1 0.093 11.4 0.1 2.2 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Mto2_bdg PF12808.7 EGO30005.1 - 1.3 9.4 8.2 0.2 12.0 4.1 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HMG_box PF00505.19 EGO30007.1 - 8.4e-12 45.3 0.1 1.6e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO30007.1 - 0.00027 21.4 0.0 0.00062 20.3 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain gag-asp_proteas PF13975.6 EGO30008.1 - 4.7e-09 36.7 0.0 5.4e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO30008.1 - 5.5e-09 35.9 0.0 6e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO30008.1 - 1.4e-06 28.9 0.0 1.6e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.8 EGO30008.1 - 0.019 15.0 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon peptidase Asp_protease PF09668.10 EGO30008.1 - 0.083 12.7 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 EGO30009.1 - 1.3e-07 31.4 1.2 1.8e-07 30.9 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO30009.1 - 0.0076 16.1 0.5 0.012 15.5 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO30009.1 - 0.014 15.0 0.3 0.02 14.5 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain IBR PF01485.21 EGO30011.1 - 5.7e-08 32.9 33.1 3.6e-06 27.1 7.5 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain T3SS_HrpK1 PF16937.5 EGO30011.1 - 0.23 11.1 0.1 0.4 10.3 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF Phage_CRI PF05144.14 EGO30012.1 - 0.054 12.8 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI Ribosomal_S13_N PF08069.12 EGO30015.1 - 4.1e-31 106.8 0.3 9.1e-31 105.7 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGO30015.1 - 1.2e-14 54.3 0.4 1.7e-14 53.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S6e PF01092.19 EGO30016.1 - 1.3e-56 189.9 0.1 2.8e-56 188.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e MKLP1_Arf_bdg PF16540.5 EGO30016.1 - 0.18 11.9 4.0 0.17 12.0 2.5 1.7 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 DEAD PF00270.29 EGO30017.1 - 9.8e-16 58.0 0.0 2.9e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO30017.1 - 1.6e-09 38.0 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO30017.1 - 5.5e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aldo_ket_red PF00248.21 EGO30018.1 - 2.1e-44 151.9 0.0 1.9e-42 145.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MIOX PF05153.15 EGO30019.1 - 2.7e-125 417.0 1.5 3.4e-125 416.6 1.5 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EGO30019.1 - 0.0025 18.0 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 HD domain HAD PF12710.7 EGO30020.1 - 2e-24 87.0 0.0 5.4e-24 85.6 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGO30020.1 - 3.3e-06 26.7 0.0 8.6e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 EGO30020.1 - 2.3e-05 24.8 0.1 0.00073 19.9 0.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EGO30020.1 - 5.7e-05 22.7 0.0 0.00013 21.6 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 EGO30020.1 - 0.0043 17.1 0.1 0.062 13.4 0.1 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.12 EGO30020.1 - 0.026 14.8 0.0 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Transket_pyr PF02779.24 EGO30021.1 - 1.2e-59 201.0 0.0 1.7e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGO30021.1 - 6.5e-46 156.6 0.0 1.2e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGO30021.1 - 7.9e-45 152.3 0.0 1.4e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal SMC_N PF02463.19 EGO30022.1 - 3.4e-31 108.4 1.6 5.3e-31 107.8 1.6 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Spc7 PF08317.11 EGO30022.1 - 1.1e-06 27.8 38.6 7.8e-05 21.7 6.2 3.2 2 1 1 3 3 3 2 Spc7 kinetochore protein AAA_21 PF13304.6 EGO30022.1 - 5.9e-05 23.0 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MscS_porin PF12795.7 EGO30022.1 - 0.00061 19.4 27.3 0.052 13.1 0.0 3.4 3 0 0 3 3 3 2 Mechanosensitive ion channel porin domain SbcCD_C PF13558.6 EGO30022.1 - 0.0012 19.0 0.0 0.004 17.3 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ADIP PF11559.8 EGO30022.1 - 0.003 17.7 38.3 0.72 9.9 19.5 3.6 3 0 0 3 3 3 3 Afadin- and alpha -actinin-Binding WEMBL PF05701.11 EGO30022.1 - 0.0035 16.1 0.2 0.0035 16.1 0.2 3.1 2 1 0 2 2 2 1 Weak chloroplast movement under blue light DUF1664 PF07889.12 EGO30022.1 - 0.0037 17.3 21.3 0.62 10.1 0.3 4.9 3 2 1 4 4 4 2 Protein of unknown function (DUF1664) GAS PF13851.6 EGO30022.1 - 0.0051 16.2 35.8 0.28 10.5 1.8 3.7 3 1 0 3 3 3 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EGO30022.1 - 0.0055 16.7 44.0 1.8 8.6 0.7 4.5 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 EGO30022.1 - 0.0073 16.3 26.4 0.13 12.3 8.2 3.9 3 1 0 3 3 3 1 Laminin Domain II HBM PF16591.5 EGO30022.1 - 0.0094 15.4 24.9 0.012 15.1 13.1 3.3 2 1 1 3 3 3 1 Helical bimodular sensor domain THOC7 PF05615.13 EGO30022.1 - 0.011 16.0 37.1 0.025 14.9 11.9 5.1 3 2 1 4 4 4 0 Tho complex subunit 7 Baculo_PEP_C PF04513.12 EGO30022.1 - 0.015 15.3 9.5 1 9.4 1.7 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EGO30022.1 - 0.021 15.2 23.2 0.052 13.9 4.9 5.4 6 1 1 7 7 4 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 EGO30022.1 - 0.023 14.4 24.9 0.79 9.4 14.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF745) EzrA PF06160.12 EGO30022.1 - 0.035 12.3 34.8 0.062 11.5 14.6 4.0 2 2 3 5 5 5 0 Septation ring formation regulator, EzrA RPW8 PF05659.11 EGO30022.1 - 0.036 13.7 13.2 0.23 11.1 0.1 4.7 3 1 3 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 APG6_N PF17675.1 EGO30022.1 - 0.038 14.5 48.9 0.25 11.9 3.4 4.3 3 1 1 4 4 4 0 Apg6 coiled-coil region AAA_13 PF13166.6 EGO30022.1 - 0.057 12.1 29.3 0.94 8.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain ATG16 PF08614.11 EGO30022.1 - 0.066 13.4 41.0 0.24 11.6 5.0 3.8 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 EGO30022.1 - 0.069 13.6 14.9 5.9 7.4 3.3 5.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 EGO30022.1 - 0.076 12.6 39.1 0.21 11.1 21.4 3.5 3 1 0 3 3 3 0 Intermediate filament protein BRE1 PF08647.11 EGO30022.1 - 0.079 13.0 31.7 0.66 10.1 0.3 4.4 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase HOOK PF05622.12 EGO30022.1 - 0.13 10.4 36.9 0.11 10.7 27.7 2.2 2 0 0 2 2 2 0 HOOK protein TPR_MLP1_2 PF07926.12 EGO30022.1 - 0.14 12.2 35.3 2.9 7.9 20.3 4.0 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 EGO30022.1 - 0.18 9.3 38.4 0.48 7.9 38.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 EGO30022.1 - 0.22 10.7 22.9 1.3 8.2 10.6 3.3 2 1 0 3 3 3 0 TMPIT-like protein DUF4201 PF13870.6 EGO30022.1 - 0.27 10.9 33.4 0.42 10.3 1.0 4.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) RasGAP_C PF03836.15 EGO30022.1 - 0.29 11.3 22.2 3.9 7.6 10.7 3.7 2 1 1 3 3 3 0 RasGAP C-terminus IL10 PF00726.17 EGO30022.1 - 0.4 10.2 4.7 0.44 10.0 2.3 2.2 2 0 0 2 2 2 0 Interleukin 10 DUF16 PF01519.16 EGO30022.1 - 0.42 11.1 22.5 9.5 6.8 11.5 4.0 3 1 0 3 3 3 0 Protein of unknown function DUF16 IFT57 PF10498.9 EGO30022.1 - 0.56 9.1 36.4 3 6.7 17.7 3.1 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF724 PF05266.14 EGO30022.1 - 0.64 9.8 30.9 0.79 9.5 1.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.12 EGO30022.1 - 0.68 9.5 35.6 31 4.0 26.1 4.3 2 1 1 3 3 3 0 PspA/IM30 family Sec8_exocyst PF04048.14 EGO30022.1 - 1.4 8.8 19.5 2.4 8.0 10.0 3.6 3 2 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF1484 PF07363.11 EGO30022.1 - 1.6 9.8 7.5 11 7.1 0.0 3.9 3 1 1 4 4 3 0 Protein of unknown function (DUF1484) OmpH PF03938.14 EGO30022.1 - 1.8 8.9 36.4 0.17 12.2 1.3 4.1 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) BST2 PF16716.5 EGO30022.1 - 1.9 9.1 28.2 0.14 12.8 9.1 4.6 3 3 1 4 4 4 0 Bone marrow stromal antigen 2 DUF2730 PF10805.8 EGO30022.1 - 2.1 8.5 13.4 29 4.8 5.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 EGO30022.1 - 2.3 8.6 21.8 5.4 7.4 10.1 4.7 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 EGO30022.1 - 3.2 7.6 6.3 27 4.7 0.3 3.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 Exonuc_VII_L PF02601.15 EGO30022.1 - 3.3 7.2 29.0 13 5.2 17.4 3.1 2 1 0 3 3 3 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EGO30022.1 - 3.4 7.9 40.2 0.89 9.8 0.9 4.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 EGO30022.1 - 3.4 8.0 16.1 1.8 8.9 2.9 4.4 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF489 PF04356.12 EGO30022.1 - 4.2 7.3 17.0 19 5.2 8.3 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF489) POTRA_TamA_1 PF17243.2 EGO30022.1 - 4.4 7.5 9.7 1.4 9.0 2.4 3.5 3 0 0 3 3 2 0 POTRA domain TamA domain 1 Fmp27_WPPW PF10359.9 EGO30022.1 - 4.7 6.0 26.9 8.3 5.1 14.8 3.1 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain FliD_N PF02465.18 EGO30022.1 - 4.8 7.9 13.0 0.33 11.7 4.6 3.3 3 1 1 4 4 3 0 Flagellar hook-associated protein 2 N-terminus DASH_Duo1 PF08651.10 EGO30022.1 - 5.1 6.9 13.9 0.57 10.0 1.2 4.3 4 1 1 5 5 3 0 DASH complex subunit Duo1 DLP_helical PF18709.1 EGO30022.1 - 5.3 6.1 25.9 3.7 6.7 2.8 3.6 2 1 1 3 3 3 0 Dynamin-like helical domain Lebercilin PF15619.6 EGO30022.1 - 5.8 6.5 39.1 0.078 12.6 1.0 3.9 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease SesA PF17107.5 EGO30022.1 - 6.2 7.0 14.0 6.8 6.9 4.2 3.4 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RbsD_FucU PF05025.13 EGO30022.1 - 6.2 7.2 7.3 2.6 8.5 0.0 3.2 3 1 0 3 3 3 0 RbsD / FucU transport protein family T3SSipB PF16535.5 EGO30022.1 - 6.7 7.2 21.7 9 6.8 0.2 4.1 2 1 2 4 4 4 0 Type III cell invasion protein SipB YscO-like PF16789.5 EGO30022.1 - 8.4 6.4 35.7 2.1 8.4 1.6 3.7 2 1 2 4 4 4 0 YscO-like protein DUF4407 PF14362.6 EGO30022.1 - 9 5.5 33.9 4.8 6.4 1.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) CorA PF01544.18 EGO30022.1 - 9.2 5.5 28.1 3.9 6.7 1.2 4.0 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein HrpB7 PF09486.10 EGO30022.1 - 9.2 6.6 32.7 0.46 10.9 1.2 4.7 3 3 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 EGO30022.1 - 9.2 6.7 39.4 0.55 10.7 7.5 3.3 1 1 1 2 2 1 0 Fez1 Methyltransf_25 PF13649.6 EGO30023.1 - 6.8e-05 23.5 0.1 0.0017 19.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO30023.1 - 0.092 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO30024.1 - 0.00032 21.3 0.0 0.0023 18.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGO30024.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MIP-T3 PF10243.9 EGO30025.1 - 0.02 14.9 0.0 0.43 10.6 0.0 2.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain DEAD PF00270.29 EGO30026.1 - 5.8e-10 39.2 0.0 8.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO30026.1 - 0.0015 18.6 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 EGO30026.1 - 0.04 12.7 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Methyltransf_25 PF13649.6 EGO30027.1 - 0.00011 22.8 0.0 0.015 16.0 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGO30027.1 - 0.086 13.5 0.0 0.3 11.7 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Usher_TcfC PF17271.2 EGO30028.1 - 0.46 9.2 0.7 0.69 8.6 0.6 1.3 1 1 1 2 2 2 0 TcfC Usher-like barrel domain F-box-like PF12937.7 EGO30029.1 - 8.3e-09 35.2 1.2 8.3e-09 35.2 1.2 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EGO30029.1 - 0.019 15.4 1.2 12 6.4 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO30029.1 - 0.26 11.1 1.2 2.5 7.9 0.0 3.1 4 0 0 4 4 4 0 Leucine rich repeat Peptidase_S9 PF00326.21 EGO30030.1 - 7.4e-33 113.8 0.2 1.3e-32 113.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EGO30030.1 - 0.0011 18.9 6.7 0.17 11.9 0.2 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 EGO30030.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGO30030.1 - 0.011 15.4 0.4 0.081 12.5 0.4 2.2 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EGO30030.1 - 0.015 14.0 0.5 0.043 12.5 0.1 1.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EGO30030.1 - 0.018 14.3 0.1 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EGO30030.1 - 0.035 13.7 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family PQQ_3 PF13570.6 EGO30030.1 - 0.049 14.1 1.4 0.28 11.7 1.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Abhydrolase_1 PF00561.20 EGO30030.1 - 0.12 12.0 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 EGO30031.1 - 1.8e-13 50.4 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO30031.1 - 2.6e-09 37.0 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO30033.1 - 2.1e-25 89.3 0.0 2.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO30033.1 - 1e-17 64.5 0.0 1.3e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO30033.1 - 5e-08 33.1 0.0 6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO30033.1 - 0.0015 18.5 0.0 0.0019 18.1 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO30033.1 - 0.0035 16.8 0.1 0.006 16.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4958 PF16319.5 EGO30033.1 - 0.17 9.9 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) DcpS_C PF11969.8 EGO30039.1 - 0.0033 17.9 0.0 0.01 16.3 0.0 1.7 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding TBP PF00352.21 EGO30039.1 - 0.073 13.0 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) F-box-like PF12937.7 EGO30040.1 - 6.1e-05 22.8 0.1 9.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 F-box-like NMD3 PF04981.13 EGO30041.1 - 6.4e-79 264.9 0.3 8.5e-79 264.4 0.3 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EGO30041.1 - 0.012 15.6 5.7 0.4 10.7 5.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.12 EGO30041.1 - 0.075 12.9 2.5 0.18 11.7 0.8 2.5 3 0 0 3 3 3 0 NinF protein TT_ORF2 PF02957.15 EGO30041.1 - 0.13 13.2 3.3 2.7 8.9 0.0 2.5 2 0 0 2 2 2 0 TT viral ORF2 Rpr2 PF04032.16 EGO30041.1 - 0.23 11.8 3.5 18 5.7 0.2 3.0 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain LRR_4 PF12799.7 EGO30042.1 - 4.2 7.9 5.6 18 5.9 0.0 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) HEAT PF02985.22 EGO30043.1 - 1.8e-12 46.3 0.8 0.00011 22.2 0.0 3.9 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 EGO30043.1 - 2.5e-09 37.4 0.6 5.7e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO30043.1 - 0.00015 22.1 1.0 0.038 14.4 0.2 3.2 1 1 1 2 2 2 2 HEAT repeats Adaptin_N PF01602.20 EGO30043.1 - 0.0003 19.5 0.0 0.0003 19.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 EGO30043.1 - 0.0086 16.6 0.1 0.15 12.6 0.0 2.7 3 0 0 3 3 3 1 HEAT-like repeat DUF4355 PF14265.6 EGO30043.1 - 0.028 14.6 0.1 0.052 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Synapsin_N PF10581.9 EGO30043.1 - 0.032 14.2 2.5 9.3 6.3 0.0 3.3 3 0 0 3 3 3 0 Synapsin N-terminal WWE PF02825.20 EGO30043.1 - 0.043 14.4 0.5 5 7.8 0.1 2.9 1 1 2 3 3 3 0 WWE domain Baculo_LEF-10 PF07206.11 EGO30043.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) ALF PF03752.13 EGO30043.1 - 0.19 11.7 0.5 13 5.8 0.0 2.5 3 0 0 3 3 3 0 Short repeats of unknown function HEAT PF02985.22 EGO30044.1 - 8.5e-05 22.5 0.1 9.2 6.8 0.0 3.2 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 EGO30044.1 - 0.01 16.2 0.2 1.3 9.4 0.0 2.2 1 1 1 2 2 2 0 HEAT repeats DUF2235 PF09994.9 EGO30045.1 - 1e-72 244.9 0.2 2.4e-72 243.7 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_38 PF18438.1 EGO30045.1 - 0.044 13.8 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 F-box-like PF12937.7 EGO30046.1 - 0.0054 16.6 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like O-FucT PF10250.9 EGO30049.1 - 5.1e-09 36.3 0.0 1.6e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF2106 PF09879.9 EGO30049.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) HMG_box PF00505.19 EGO30051.1 - 5.3e-11 42.8 0.4 9.2e-11 42.0 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO30051.1 - 0.00029 21.4 0.1 0.00058 20.4 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Pyocin_S PF06958.12 EGO30057.1 - 0.051 14.1 0.9 0.051 14.1 0.9 1.8 1 1 1 2 2 2 0 S-type Pyocin HAT PF02184.16 EGO30057.1 - 0.22 11.5 0.1 0.38 10.8 0.1 1.3 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat GEMIN8 PF15348.6 EGO30057.1 - 0.26 11.6 6.5 0.4 10.9 6.5 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 F-box-like PF12937.7 EGO30059.1 - 0.052 13.5 0.9 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 F-box-like Tnp_22_trimer PF17489.2 EGO30060.1 - 0.048 13.6 0.9 0.065 13.2 0.1 1.6 2 0 0 2 2 2 0 L1 transposable element trimerization domain DNApol_Exo PF18136.1 EGO30061.1 - 1.2e-99 333.0 0.0 2.3e-99 332.1 0.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EGO30061.1 - 9.1e-49 166.5 0.0 4.3e-48 164.3 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family A RFC1 PF08519.12 EGO30061.1 - 0.054 13.7 0.8 0.97 9.6 0.2 2.7 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain Cellulase PF00150.18 EGO30067.1 - 2.8e-13 49.9 0.0 4.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) YXWGXW PF12779.7 EGO30069.1 - 0.073 13.2 3.4 0.34 11.1 3.4 2.3 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) FAD_binding_4 PF01565.23 EGO30071.1 - 2.8e-21 75.7 2.3 4.4e-21 75.1 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO30071.1 - 3.1e-05 24.0 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 EGO30072.1 - 6.4e-39 133.9 50.6 7.9e-39 133.6 48.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO30072.1 - 5.3e-23 81.3 13.5 7.4e-23 80.8 13.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO30072.1 - 3.4e-14 52.6 10.3 3.4e-14 52.6 10.3 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter CMAS PF02353.20 EGO30073.1 - 2.9e-52 177.7 0.4 4.3e-52 177.1 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO30073.1 - 7.2e-08 33.0 0.0 1.9e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO30073.1 - 9.9e-07 29.3 0.1 2.7e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO30073.1 - 1.1e-06 28.5 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO30073.1 - 0.0017 18.2 0.0 0.0081 16.0 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO30073.1 - 0.033 14.9 0.0 0.079 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGO30073.1 - 0.055 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 EGO30073.1 - 0.11 12.1 0.0 1.2 8.8 0.0 2.5 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 RC-P840_PscD PF10657.9 EGO30074.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD GH131_N PF18271.1 EGO30075.1 - 1.6e-75 254.1 0.0 1.8e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 EGO30075.1 - 0.11 12.4 0.1 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide lyase FMN_red PF03358.15 EGO30076.1 - 1.4e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EGO30076.1 - 0.092 13.0 0.0 0.51 10.5 0.0 2.0 1 1 0 1 1 1 0 Flavodoxin FMN_red PF03358.15 EGO30077.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGO30077.1 - 4.6e-05 23.2 0.0 6.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EGO30077.1 - 0.059 13.6 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 Flavodoxin Hydrophobin PF01185.18 EGO30078.1 - 2.6e-24 85.6 6.7 3.2e-24 85.4 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EGO30079.1 - 1.6e-26 92.7 5.5 2.3e-26 92.2 5.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin PAS_9 PF13426.7 EGO30080.1 - 2.8e-23 82.1 0.0 4.5e-14 52.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EGO30080.1 - 2.2e-13 50.3 0.0 2.9e-07 30.7 0.0 4.4 3 2 0 3 3 3 2 PAS fold PAS PF00989.25 EGO30080.1 - 1.1e-11 44.7 0.0 2.9e-06 27.2 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 EGO30080.1 - 2.1e-07 31.1 0.0 0.0006 20.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 EGO30080.1 - 2.8e-05 24.2 0.0 0.00031 20.8 0.0 2.5 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EGO30080.1 - 0.14 12.2 0.0 24 5.1 0.0 2.7 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.25 EGO30081.1 - 2e-44 151.9 0.0 2.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30081.1 - 3.2e-23 82.3 0.0 4.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGO30081.1 - 0.001 18.2 0.3 0.0017 17.4 0.0 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EGO30081.1 - 0.031 14.2 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyocin_S PF06958.12 EGO30081.1 - 1 9.9 4.9 6.6 7.3 0.1 2.7 2 0 0 2 2 2 0 S-type Pyocin Ribosomal_L44 PF00935.19 EGO30082.1 - 1.3e-37 128.1 11.7 2.1e-37 127.5 11.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 EGO30082.1 - 0.018 15.4 0.7 0.034 14.4 0.7 1.4 1 0 0 1 1 1 0 Cathelicidin AAA_12 PF13087.6 EGO30083.1 - 3.4e-43 147.6 0.0 5e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO30083.1 - 8.7e-29 101.1 4.7 5.5e-24 85.3 1.5 2.2 1 1 1 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 EGO30083.1 - 0.0076 16.1 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain RdRP PF05183.12 EGO30084.1 - 1.8e-103 347.2 0.0 2.7e-103 346.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sec63 PF02889.16 EGO30085.1 - 2.1e-156 518.7 0.0 2.2e-83 279.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGO30085.1 - 6.7e-49 166.0 0.3 3.5e-26 92.0 0.2 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGO30085.1 - 2.7e-34 117.7 0.0 7.9e-34 116.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EGO30085.1 - 3.1e-24 85.9 0.9 3.7e-15 56.4 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO30085.1 - 3.7e-14 53.0 0.0 4.3e-08 33.5 0.0 4.3 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGO30085.1 - 1.5e-06 28.5 0.1 0.056 13.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EGO30085.1 - 0.0015 18.1 0.0 0.044 13.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EGO30085.1 - 0.0039 16.3 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EGO30085.1 - 0.0087 15.6 0.0 2.7 7.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF603 PF04645.12 EGO30085.1 - 0.041 13.6 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Sigma54_activ_2 PF14532.6 EGO30085.1 - 0.16 12.0 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain WD40 PF00400.32 EGO30086.1 - 1.5e-09 38.3 3.3 0.13 13.2 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat SRA1 PF07304.11 EGO30086.1 - 4.1e-08 33.1 0.0 4.1e-08 33.1 0.0 3.5 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 EGO30086.1 - 0.044 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain Sec16_C PF12931.7 EGO30086.1 - 0.056 13.1 1.0 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 Sec23-binding domain of Sec16 Pkinase_Tyr PF07714.17 EGO30087.1 - 1.7e-41 142.2 0.0 2.4e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO30087.1 - 1.3e-38 132.8 0.0 2.3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGO30087.1 - 0.0038 16.6 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO30087.1 - 0.015 15.3 0.2 0.055 13.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family PRP21_like_P PF12230.8 EGO30087.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Sgf11 PF08209.11 EGO30087.1 - 1.3 8.7 7.0 8.2 6.1 0.2 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf_C2HC_14 PF18574.1 EGO30087.1 - 2 8.2 4.5 2.3 8.1 2.6 2.0 2 0 0 2 2 2 0 C2HC Zing finger domain Pkinase_Tyr PF07714.17 EGO30088.1 - 1.1e-36 126.5 0.0 1.6e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO30088.1 - 1.8e-34 119.3 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO30088.1 - 0.023 14.6 0.2 0.065 13.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S26e PF01283.19 EGO30089.1 - 8.1e-54 180.6 9.2 9.6e-54 180.4 9.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EGO30089.1 - 0.0069 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Zinc binding domain zf-C2H2_jaz PF12171.8 EGO30090.1 - 1.5e-11 44.2 28.2 0.51 10.7 0.1 8.6 9 0 0 9 9 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGO30090.1 - 1.2e-10 41.2 59.0 0.1 13.5 0.2 12.1 11 1 1 12 12 12 6 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO30090.1 - 3.1e-10 39.9 54.6 0.019 15.4 0.2 10.7 11 1 1 12 12 11 6 Zinc finger, C2H2 type zf-C3HC4 PF00097.25 EGO30090.1 - 3.7e-05 23.5 13.4 3.7e-05 23.5 13.4 4.9 5 2 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO30090.1 - 4.8e-05 23.2 13.8 4.8e-05 23.2 13.8 4.6 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO30090.1 - 0.00026 20.8 12.9 0.00026 20.8 12.9 4.3 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.6 EGO30090.1 - 0.00036 20.5 36.7 0.023 14.7 0.1 7.7 7 1 1 8 8 7 4 C2H2-type zinc finger zf-RING_2 PF13639.6 EGO30090.1 - 0.0024 18.2 13.5 0.0024 18.2 13.5 5.5 4 2 1 5 5 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO30090.1 - 0.0044 16.8 12.2 0.0044 16.8 12.2 5.2 4 2 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 EGO30090.1 - 0.0055 17.1 45.7 0.033 14.6 0.1 10.3 11 1 0 11 11 11 2 Zinc-finger of C2H2 type Prok-RING_4 PF14447.6 EGO30090.1 - 0.0093 15.8 11.1 0.0093 15.8 11.1 4.3 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGO30090.1 - 0.015 15.3 5.8 0.015 15.3 5.8 4.5 3 1 1 4 4 4 0 RING-type zinc-finger zf-C2H2_11 PF16622.5 EGO30090.1 - 0.023 14.4 18.9 0.52 10.1 0.6 6.5 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-ACC PF17848.1 EGO30090.1 - 0.03 14.4 0.2 0.03 14.4 0.2 4.2 5 0 0 5 5 4 0 Acetyl-coA carboxylase zinc finger domain zf_Hakai PF18408.1 EGO30090.1 - 0.14 11.9 4.7 0.28 10.9 2.7 2.7 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-RING_6 PF14835.6 EGO30090.1 - 5 7.1 11.9 0.79 9.6 7.3 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein RT_RNaseH PF17917.1 EGO30091.1 - 3.4e-36 123.7 0.1 7.4e-36 122.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGO30091.1 - 5.9e-36 122.5 0.0 1.1e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EGO30091.1 - 1.5e-29 103.1 0.1 8.3e-29 100.7 0.2 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EGO30091.1 - 1.4e-20 73.1 0.1 3e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGO30091.1 - 5.2e-19 68.6 0.0 1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EGO30091.1 - 1.3e-13 50.7 0.1 2.9e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 EGO30091.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO30091.1 - 0.025 15.1 0.0 0.089 13.4 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 EGO30091.1 - 0.031 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 EGO30091.1 - 0.13 13.0 0.0 0.33 11.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease UCH PF00443.29 EGO30092.1 - 2.5e-41 141.9 0.0 4.2e-41 141.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO30092.1 - 1.9e-09 37.6 0.0 0.00021 21.0 0.0 3.4 2 1 1 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_1 PF00232.18 EGO30093.1 - 3.4e-154 513.6 3.1 4.4e-154 513.2 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 adh_short PF00106.25 EGO30094.1 - 6.3e-21 74.7 0.1 8.2e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO30094.1 - 6.3e-16 58.6 0.0 7.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO30094.1 - 0.0013 18.7 0.1 0.0037 17.2 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO30094.1 - 0.061 12.8 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EGO30095.1 - 3.8e-38 130.6 0.0 5.8e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO30095.1 - 3.2e-25 88.3 0.0 3.5e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EGO30095.1 - 4.7e-05 23.9 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGO30095.1 - 0.00033 20.8 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EGO30095.1 - 0.13 13.1 0.0 0.49 11.2 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF3277 PF11681.8 EGO30095.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Pribosyltran PF00156.27 EGO30096.1 - 6.5e-14 51.7 1.2 1.1e-13 51.0 1.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DER1 PF04511.15 EGO30097.1 - 4.2e-31 108.4 2.3 5.3e-31 108.0 2.3 1.0 1 0 0 1 1 1 1 Der1-like family DUF2046 PF09755.9 EGO30098.1 - 2.4e-12 46.7 4.3 2.4e-12 46.7 4.3 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) HSP20 PF00011.21 EGO30098.1 - 6.6e-11 42.3 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pex19 PF04614.12 EGO30098.1 - 0.12 12.1 1.5 0.22 11.2 1.5 1.3 1 0 0 1 1 1 0 Pex19 protein family FlaC_arch PF05377.11 EGO30098.1 - 0.36 11.3 1.5 4.4 7.8 0.0 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CK2S PF15011.6 EGO30098.1 - 6.1 6.7 7.8 0.18 11.7 0.9 2.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate Pkinase PF00069.25 EGO30100.1 - 9.7e-08 31.7 0.2 4.4e-07 29.5 0.1 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30100.1 - 0.0064 15.8 0.2 0.046 13.0 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGO30100.1 - 0.0095 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGO30100.1 - 0.15 11.9 0.0 1.3 8.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Helicase_C PF00271.31 EGO30101.1 - 1.7e-08 34.8 0.0 3.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGO30101.1 - 6e-05 22.4 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Mitofilin PF09731.9 EGO30101.1 - 5.7 5.7 8.5 11 4.7 8.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SNF2_N PF00176.23 EGO30102.1 - 8.3e-06 24.7 0.0 0.00012 21.0 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain SNF2_N PF00176.23 EGO30103.1 - 8.3e-13 47.8 1.4 1.1e-12 47.4 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EGO30103.1 - 0.00035 20.6 0.0 0.0007 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGO30104.1 - 1.3e-09 37.3 0.0 2.6e-08 33.0 0.0 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.29 EGO30104.1 - 0.045 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase YqjK PF13997.6 EGO30105.1 - 0.013 15.8 0.2 0.021 15.1 0.2 1.4 1 0 0 1 1 1 0 YqjK-like protein HhH-GPD PF00730.25 EGO30107.1 - 0.00064 20.2 0.0 0.00065 20.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TIP49 PF06068.13 EGO30108.1 - 4.6e-157 522.7 0.0 5.4e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGO30108.1 - 6e-19 67.9 0.0 1.3e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGO30108.1 - 6.3e-10 39.6 0.1 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO30108.1 - 1.4e-08 34.7 0.0 6.7e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGO30108.1 - 1.7e-06 28.4 0.1 0.03 14.6 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGO30108.1 - 1.4e-05 25.1 0.1 0.0078 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO30108.1 - 4.2e-05 24.0 0.0 0.0004 20.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGO30108.1 - 0.00086 18.9 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO30108.1 - 0.0009 19.5 0.0 0.003 17.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGO30108.1 - 0.0052 17.1 1.3 0.051 13.9 1.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO30108.1 - 0.033 14.3 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO30108.1 - 0.034 14.7 0.1 0.3 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGO30108.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGO30108.1 - 0.046 13.1 0.1 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGO30108.1 - 0.077 12.7 0.0 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGO30108.1 - 0.093 12.0 0.2 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EGO30108.1 - 0.097 12.2 0.1 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 EGO30108.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGO30108.1 - 0.23 11.5 0.0 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CBFD_NFYB_HMF PF00808.23 EGO30110.1 - 2.4e-21 75.8 1.0 3e-21 75.5 1.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO30110.1 - 7.6e-13 49.0 0.1 8.4e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EGO30110.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.5 2 0 0 2 2 2 1 CENP-S associating Centromere protein X TAF PF02969.17 EGO30110.1 - 0.038 14.2 0.5 0.059 13.6 0.3 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) TAFII28 PF04719.14 EGO30110.1 - 0.072 13.2 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DnaJ PF00226.31 EGO30111.1 - 1.7e-19 69.7 0.3 1.7e-19 69.7 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EGO30111.1 - 6.9e-18 64.9 1.9 5.1e-05 23.7 0.0 6.8 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGO30111.1 - 5.1e-17 60.9 4.5 0.00028 20.6 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO30111.1 - 6.7e-14 50.8 12.0 0.0014 18.6 0.0 6.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGO30111.1 - 1.8e-12 47.2 1.5 0.04 14.1 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO30111.1 - 5.7e-11 41.7 0.1 0.021 15.0 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO30111.1 - 1e-10 41.1 0.1 9.9e-06 25.1 0.1 5.0 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.6 EGO30111.1 - 1.2e-10 41.8 9.2 0.00016 22.2 0.0 5.5 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO30111.1 - 4.9e-10 39.4 6.1 0.61 11.0 0.0 6.2 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO30111.1 - 2.2e-08 33.5 2.0 3 8.1 0.0 6.0 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO30111.1 - 1.2e-07 32.0 3.3 0.56 10.5 0.1 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGO30111.1 - 2.7e-06 27.6 6.2 2.3 9.0 0.1 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO30111.1 - 1e-05 25.7 7.5 0.03 14.5 0.5 5.1 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGO30111.1 - 1.8e-05 24.8 2.4 0.097 13.1 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 EGO30111.1 - 0.00034 21.1 5.6 0.037 14.5 0.0 3.9 3 2 0 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 EGO30111.1 - 0.0049 16.7 3.7 4.3 7.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.9 EGO30111.1 - 0.025 13.3 0.0 0.079 11.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_21 PF09976.9 EGO30111.1 - 0.099 12.3 7.2 1.8 8.2 0.4 3.8 3 2 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EGO30111.1 - 0.72 10.7 6.8 21 6.1 1.5 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 EGO30112.1 - 8.2e-45 152.3 0.0 1.3e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO30112.1 - 1.6e-18 66.7 0.0 2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO30112.1 - 1.3e-05 25.5 0.0 4e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGO30112.1 - 0.024 14.7 0.1 0.22 11.6 0.0 2.5 3 2 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EGO30112.1 - 0.12 13.2 0.0 0.43 11.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Peroxidase_2 PF01328.17 EGO30113.1 - 3.2e-48 164.7 0.0 5.1e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Coilin_N PF15862.5 EGO30114.1 - 3.6e-08 33.3 1.2 3.6e-08 33.3 1.2 2.3 2 0 0 2 2 2 1 Coilin N-terminus CDC45 PF02724.14 EGO30114.1 - 0.13 10.5 4.4 0.19 10.0 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM199X PF15814.5 EGO30114.1 - 0.42 9.6 12.9 0.71 8.9 12.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X SPATA3 PF15662.5 EGO30114.1 - 0.93 10.1 21.0 4.8 7.8 14.7 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family PI3K_1B_p101 PF10486.9 EGO30114.1 - 2 6.1 7.6 2.9 5.6 7.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EGO30114.1 - 2.9 6.4 11.3 4.5 5.7 11.3 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGO30114.1 - 5.9 5.6 11.7 9 5.0 11.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAML PF14963.6 EGO30114.1 - 8.4 6.4 7.2 15 5.6 7.2 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ifi-6-16 PF06140.13 EGO30115.1 - 2.4e-06 27.4 0.3 3.4e-06 26.9 0.3 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family UPRTase PF14681.6 EGO30116.1 - 2.6e-77 259.0 0.0 3e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGO30116.1 - 0.0016 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ifi-6-16 PF06140.13 EGO30117.1 - 3.2e-05 23.8 0.2 5.4e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF1858 PF08984.11 EGO30117.1 - 0.015 15.4 0.3 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) DUF4564 PF15169.6 EGO30117.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) NOG1_N PF17835.1 EGO30117.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 1 0 1 1 1 0 NOG1 N-terminal helical domain DUF768 PF05589.11 EGO30117.1 - 0.25 11.4 2.1 0.31 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF768) ACT_3 PF10000.9 EGO30118.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 ACT domain Pkinase_fungal PF17667.1 EGO30119.1 - 3.8e-51 174.1 0.0 6.1e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO30119.1 - 7.2e-07 28.8 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30119.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EMG1 PF03587.14 EGO30121.1 - 4.7e-76 254.8 0.0 5.8e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SPX PF03105.19 EGO30121.1 - 1.3 8.9 9.4 1.7 8.5 9.4 1.1 1 0 0 1 1 1 0 SPX domain CRAL_TRIO PF00650.20 EGO30122.1 - 2.3e-34 118.4 0.0 3.1e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO30122.1 - 4.6e-11 42.7 0.1 9.4e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain p450 PF00067.22 EGO30123.1 - 8.1e-70 235.8 0.0 1.1e-69 235.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO30124.1 - 4.7e-68 230.0 0.2 2.4e-46 158.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 HK_sensor PF16750.5 EGO30124.1 - 0.047 14.0 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sensor domain of 2-component histidine kinase Actin PF00022.19 EGO30125.1 - 6.6e-147 489.4 0.0 4.7e-146 486.6 0.0 1.8 1 1 0 1 1 1 1 Actin RPE65 PF03055.15 EGO30127.1 - 4.9e-119 398.6 0.0 5.9e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein VWA_2 PF13519.6 EGO30131.1 - 3e-24 85.7 0.1 2.1e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EGO30131.1 - 2.2e-08 34.5 0.1 3.6e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EGO30131.1 - 4.4e-08 33.2 0.2 9.2e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.20 EGO30131.1 - 8.9e-08 31.5 32.7 0.00016 21.4 1.7 4.1 4 0 0 4 4 4 3 Ubiquitin interaction motif SCO1-SenC PF02630.14 EGO30132.1 - 1.1e-44 151.6 0.0 1.7e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EGO30132.1 - 0.0073 16.2 0.0 0.037 14.0 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGO30132.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like CGI-121 PF08617.10 EGO30133.1 - 1.9e-49 167.9 0.3 2.1e-49 167.7 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 EGO30134.1 - 5.5e-47 158.0 0.2 3.5e-24 84.8 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGO30134.1 - 1e-17 64.6 0.0 1.4e-09 38.2 0.0 4.1 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGO30134.1 - 4.3e-06 27.0 0.0 0.017 15.4 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 EGO30134.1 - 5.8e-05 22.6 0.2 0.5 9.7 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGO30134.1 - 0.00014 22.2 0.5 0.024 15.1 0.1 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGO30134.1 - 0.011 15.8 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain GcpE PF04551.14 EGO30134.1 - 0.063 12.4 0.0 0.52 9.3 0.0 2.0 2 0 0 2 2 2 0 GcpE protein Thioredoxin_7 PF13899.6 EGO30134.1 - 0.13 12.4 0.7 9.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like GCM PF03615.15 EGO30134.1 - 0.14 12.0 0.5 0.95 9.3 0.2 2.3 2 0 0 2 2 2 0 GCM motif protein PPR_2 PF13041.6 EGO30135.1 - 1.7e-39 133.7 0.0 2.4e-07 30.8 0.0 13.5 12 3 3 15 15 15 8 PPR repeat family PPR PF01535.20 EGO30135.1 - 1.4e-34 115.9 5.4 0.00089 19.4 0.0 13.2 14 0 0 14 14 14 6 PPR repeat PPR_1 PF12854.7 EGO30135.1 - 9e-27 92.5 0.9 6e-06 25.9 0.0 10.2 10 0 0 10 10 10 5 PPR repeat PPR_3 PF13812.6 EGO30135.1 - 2.6e-20 72.3 0.1 0.0028 17.7 0.0 10.8 8 4 7 15 15 15 5 Pentatricopeptide repeat domain PPR_long PF17177.4 EGO30135.1 - 6.3e-11 42.0 4.5 2.7e-07 30.2 0.2 4.7 2 2 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EGO30135.1 - 2.8e-06 27.7 5.9 2.7 9.0 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO30135.1 - 1.1e-05 25.9 0.1 2.4 8.7 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat ATP13 PF12921.7 EGO30135.1 - 0.017 15.0 0.0 7.5 6.4 0.0 4.8 3 1 1 4 4 4 0 Mitochondrial ATPase expression Wzy_C_2 PF11846.8 EGO30135.1 - 0.032 14.2 2.9 2.7 7.9 0.0 4.2 6 0 0 6 6 6 0 Virulence factor membrane-bound polymerase, C-terminal RPM2 PF08579.11 EGO30135.1 - 0.14 12.6 0.6 4.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_6 PF13174.6 EGO30135.1 - 0.34 11.6 4.7 35 5.3 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO30135.1 - 0.89 10.2 4.2 11 6.8 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Sec_GG PF07549.14 EGO30136.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 SecD/SecF GG Motif Plavaka PF18759.1 EGO30139.1 - 1.9e-39 135.8 0.2 3.6e-39 134.9 0.2 1.4 1 1 0 1 1 1 1 Plavaka transposase XK-related PF09815.9 EGO30141.1 - 0.03 13.4 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 XK-related protein Ifi-6-16 PF06140.13 EGO30142.1 - 5.5e-05 23.0 14.8 9.2e-05 22.3 14.8 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF2065 PF09838.9 EGO30142.1 - 0.006 16.6 2.4 0.18 11.9 0.1 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2065) DUF3185 PF11381.8 EGO30142.1 - 0.46 10.5 8.5 0.1 12.6 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Bac_rhamnosid6H PF17389.2 EGO30143.1 - 4.4e-15 55.8 1.9 6.6e-15 55.2 1.9 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EGO30143.1 - 5.5e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 EGO30143.1 - 3e-06 26.3 0.2 4.6e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 EGO30143.1 - 0.026 13.2 0.9 0.041 12.6 0.9 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF608 PF04685.13 EGO30143.1 - 0.043 13.0 2.6 0.069 12.3 2.6 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region F_bP_aldolase PF01116.20 EGO30144.1 - 2.6e-93 312.6 0.0 2.9e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.11 EGO30144.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Flavin_Reduct PF01613.18 EGO30147.1 - 5.6e-17 62.2 0.0 8.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Npa1 PF11707.8 EGO30148.1 - 3.6e-101 338.9 0.8 2.6e-99 332.8 0.0 3.3 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EGO30148.1 - 5e-55 186.2 2.7 1e-54 185.2 1.4 2.3 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Abhydrolase_6 PF12697.7 EGO30149.1 - 2.6e-09 38.0 0.9 3.1e-09 37.8 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AIRC PF00731.20 EGO30150.1 - 7.3e-62 207.3 1.3 8.3e-62 207.2 0.5 1.5 2 0 0 2 2 2 1 AIR carboxylase PurK_C PF17769.1 EGO30150.1 - 1.8e-20 72.4 0.0 3.3e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain ATP-grasp PF02222.22 EGO30150.1 - 1.7e-10 40.7 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Rsa3 PF14615.6 EGO30151.1 - 3.9e-15 55.1 0.1 5.4e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SURF2 PF05477.11 EGO30151.1 - 0.28 10.8 1.9 0.39 10.4 1.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SOG2 PF10428.9 EGO30151.1 - 3.7 6.7 11.8 4.3 6.4 11.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cyclin_N PF00134.23 EGO30152.1 - 3.4e-10 39.8 0.5 2.7e-09 36.8 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGO30152.1 - 0.0024 17.9 0.2 0.0054 16.7 0.2 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EGO30152.1 - 0.024 15.0 0.0 0.064 13.6 0.0 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain Ldh_1_C PF02866.18 EGO30153.1 - 2.6e-49 167.4 0.0 5.8e-49 166.2 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGO30153.1 - 5.4e-39 133.5 0.1 7.7e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGO30153.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGO30153.1 - 0.0054 17.2 0.6 0.02 15.3 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain WGG PF10273.9 EGO30154.1 - 4.1e-27 94.6 0.0 5.9e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 CLP1_P PF16575.5 EGO30155.1 - 5.6e-34 117.6 0.0 2.1e-33 115.7 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EGO30155.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGO30155.1 - 0.033 13.5 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EGO30155.1 - 0.088 13.2 0.1 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EGO30155.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cwf_Cwc_15 PF04889.12 EGO30155.1 - 0.22 11.3 6.4 0.35 10.5 6.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 EGO30155.1 - 5.8 7.3 9.6 2.8 8.4 4.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SfLAP PF11139.8 EGO30156.1 - 0.25 10.7 2.2 0.52 9.7 2.2 1.4 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Hemerythrin PF01814.23 EGO30157.1 - 2.7e-10 41.0 0.9 5.5e-10 40.0 1.0 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF4795 PF16043.5 EGO30157.1 - 0.15 11.6 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Asp PF00026.23 EGO30161.1 - 2.4e-12 46.9 0.0 2e-11 43.9 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Cpn60_TCP1 PF00118.24 EGO30162.1 - 5.7e-144 480.4 14.5 6.4e-144 480.2 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EGO30162.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat PMT PF02366.18 EGO30163.1 - 4.7e-79 265.4 16.2 1.1e-78 264.3 16.2 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGO30163.1 - 1.2e-68 230.6 10.4 1.2e-68 230.6 10.4 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGO30163.1 - 2e-40 138.7 0.2 3.1e-40 138.0 0.2 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EGO30163.1 - 0.00011 22.5 12.4 0.00011 22.5 12.4 3.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 EGO30163.1 - 0.37 11.4 3.9 32 5.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) PPR_2 PF13041.6 EGO30165.1 - 3.3e-09 36.8 0.3 1.8e-05 24.8 0.0 3.5 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EGO30165.1 - 2.7e-06 27.4 0.2 0.0048 17.0 0.0 3.1 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO30165.1 - 0.00081 19.0 1.2 0.31 10.8 0.0 3.6 4 0 0 4 4 4 1 PPR repeat PPR PF01535.20 EGO30165.1 - 0.012 15.8 0.1 6.8 7.2 0.0 3.5 4 0 0 4 4 4 0 PPR repeat ECSIT PF06239.11 EGO30165.1 - 0.16 11.1 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Thymidylat_synt PF00303.19 EGO30166.1 - 3.4e-107 357.5 0.0 3.9e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HD PF01966.22 EGO30167.1 - 7.3e-11 42.4 1.4 1.3e-10 41.5 0.2 2.1 3 0 0 3 3 3 1 HD domain Phg_2220_C PF09524.10 EGO30167.1 - 0.0079 16.2 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Conserved phage C-terminus (Phg_2220_C) PDEase_I PF00233.19 EGO30167.1 - 0.079 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase p450 PF00067.22 EGO30169.1 - 8e-57 193.0 0.0 5.8e-35 120.9 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 zf-CCHC PF00098.23 EGO30170.1 - 1.2e-06 28.3 2.8 1.2e-06 28.3 2.8 1.9 2 0 0 2 2 2 1 Zinc knuckle CpXC PF14353.6 EGO30170.1 - 0.066 13.2 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 CpXC protein Pkinase_fungal PF17667.1 EGO30172.1 - 5.4e-27 94.6 0.0 1.9e-08 33.5 0.0 3.5 2 1 1 3 3 3 3 Fungal protein kinase ANAPC4_WD40 PF12894.7 EGO30173.1 - 0.018 15.3 0.0 1.8 9.0 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGO30173.1 - 0.035 13.1 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 EGO30174.1 - 1.4e-16 60.5 2.0 2.6e-08 34.4 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO30174.1 - 2.6e-08 34.0 0.2 1e-05 25.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 EGO30174.1 - 0.012 15.9 2.0 0.061 13.7 1.8 2.2 2 0 0 2 2 2 0 Ring finger domain HOOK PF05622.12 EGO30174.1 - 0.014 13.6 4.9 0.018 13.2 4.9 1.1 1 0 0 1 1 1 0 HOOK protein zf-C3HC4_2 PF13923.6 EGO30174.1 - 0.014 15.2 1.3 0.014 15.2 1.3 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Ge1_WD40 PF16529.5 EGO30174.1 - 0.023 13.7 0.0 0.056 12.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1272 PF06906.11 EGO30174.1 - 0.033 14.3 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 EGO30174.1 - 0.058 13.3 3.3 0.16 11.8 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fmp27_WPPW PF10359.9 EGO30174.1 - 0.073 11.9 3.4 0.1 11.5 3.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-RING_10 PF16685.5 EGO30174.1 - 0.083 13.0 0.4 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Beta_helix_2 PF18835.1 EGO30174.1 - 0.094 12.5 0.8 6.9 6.5 0.0 2.9 1 1 1 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-RING_5 PF14634.6 EGO30174.1 - 0.11 12.5 3.7 0.48 10.4 3.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 EGO30174.1 - 0.12 11.8 0.6 0.29 10.6 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain APG6_N PF17675.1 EGO30174.1 - 0.29 11.6 5.6 0.43 11.1 5.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 EGO30174.1 - 0.3 10.7 5.5 0.47 10.1 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spectrin PF00435.21 EGO30174.1 - 0.51 10.8 4.8 0.92 10.0 4.8 1.3 1 0 0 1 1 1 0 Spectrin repeat TackOD1 PF18551.1 EGO30174.1 - 3.1 7.4 5.5 0.24 11.0 0.1 1.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 EF-hand_4 PF12763.7 EGO30175.1 - 1.2e-13 50.9 0.0 1.1e-08 35.0 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand ATP-synt_DE PF00401.20 EGO30177.1 - 0.026 14.8 1.1 0.049 13.9 1.1 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain JAB PF01398.21 EGO30181.1 - 1.3e-11 44.5 0.1 2.6e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DNA_pol_A_exo1 PF01612.20 EGO30182.1 - 0.042 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease DUF775 PF05603.12 EGO30182.1 - 0.07 12.7 0.6 0.086 12.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) BsuBI_PstI_RE PF06616.11 EGO30182.1 - 0.072 12.4 0.0 0.8 9.0 0.0 2.0 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease domain SH3_1 PF00018.28 EGO30186.1 - 1.2e-11 44.0 0.1 2e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO30186.1 - 7.8e-09 35.1 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO30186.1 - 1e-07 31.7 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EGO30186.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain WAC_Acf1_DNA_bd PF10537.9 EGO30189.1 - 9.5e-35 119.2 0.4 3e-34 117.5 0.4 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EGO30189.1 - 6.7e-32 109.9 0.7 6.1e-31 106.8 0.0 2.9 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EGO30189.1 - 3e-16 59.5 0.5 8.2e-16 58.1 0.5 1.7 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGO30189.1 - 5.2e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF5383 PF17355.2 EGO30189.1 - 1 9.7 4.6 15 5.9 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5383) CENP-H PF05837.12 EGO30189.1 - 1.5 9.3 14.3 0.38 11.2 0.1 3.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) HPP PF04982.13 EGO30190.1 - 0.069 13.3 0.5 0.098 12.8 0.5 1.4 1 1 0 1 1 1 0 HPP family P120R PF08062.11 EGO30194.1 - 0.42 11.0 2.5 0.91 10.0 0.1 2.3 2 0 0 2 2 2 0 P120R (NUC006) repeat Ribosomal_S24e PF01282.19 EGO30196.1 - 3.5e-34 116.6 0.1 6.3e-34 115.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e EutK_C PF16365.5 EGO30197.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Plavaka PF18759.1 EGO30199.1 - 4e-12 46.0 3.0 5.4e-12 45.6 3.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Myosin_head PF00063.21 EGO30202.1 - 1.5e-234 780.2 4.4 1.9e-234 779.9 4.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGO30202.1 - 9.1e-48 162.4 0.0 1.6e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_2 PF07653.17 EGO30202.1 - 1.5e-08 34.2 0.0 3.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO30202.1 - 2.6e-08 33.3 1.0 5.2e-08 32.4 1.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO30202.1 - 6.3e-08 32.4 0.1 1.4e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EGO30202.1 - 6e-05 23.2 0.3 0.00016 21.9 0.3 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 EGO30202.1 - 0.016 15.6 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EGO30202.1 - 0.031 13.8 1.5 6 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 EGO30202.1 - 0.048 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO30202.1 - 0.051 13.7 0.0 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO30202.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 EGO30202.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EGO30202.1 - 0.18 12.1 0.1 2.9 8.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Plavaka PF18759.1 EGO30203.1 - 1.6e-20 73.6 0.1 2.6e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase RVT_2 PF07727.14 EGO30204.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Aconitase_2_N PF06434.13 EGO30204.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus DDE_3 PF13358.6 EGO30206.1 - 0.0067 16.2 0.0 0.02 14.6 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF5321 PF17254.2 EGO30207.1 - 0.033 13.6 1.0 1.6 8.2 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5321) AIM3 PF17096.5 EGO30207.1 - 2.1 9.3 7.9 0.72 10.8 1.1 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Calpain_u2 PF16648.5 EGO30207.1 - 4.9 7.7 7.4 0.69 10.4 0.4 2.3 2 1 0 2 2 2 0 Unstructured region on Calpain-3 SNAPc_SNAP43 PF09808.9 EGO30208.1 - 7.4e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 zf-CCHC PF00098.23 EGO30209.1 - 5e-08 32.7 5.9 1e-07 31.7 5.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30209.1 - 0.00015 22.0 4.6 0.00015 22.0 4.6 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO30209.1 - 0.017 15.1 2.4 0.034 14.1 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF842 PF05811.13 EGO30209.1 - 0.087 12.5 4.3 0.22 11.2 4.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ribosomal_L13e PF01294.18 EGO30210.1 - 5.2e-71 238.2 4.7 7.1e-71 237.8 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e CDC73_N PF16050.5 EGO30210.1 - 0.035 13.4 0.2 0.038 13.3 0.2 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal SDA1 PF05285.12 EGO30212.1 - 0.22 10.9 6.1 0.34 10.3 6.1 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGO30212.1 - 3.4 6.9 11.1 4.9 6.4 11.1 1.1 1 0 0 1 1 1 0 BUD22 Pkinase_fungal PF17667.1 EGO30213.1 - 1e-11 44.3 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Plavaka PF18759.1 EGO30214.1 - 3e-13 49.7 0.5 4.2e-13 49.2 0.5 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-met PF12874.7 EGO30214.1 - 0.011 16.1 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGO30214.1 - 0.054 13.8 0.3 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EGO30214.1 - 0.081 13.0 0.7 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGO30214.1 - 0.55 11.2 0.1 0.55 11.2 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1848 PF08902.11 EGO30215.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Retrotrans_gag PF03732.17 EGO30217.1 - 3.5e-07 30.4 0.3 3.5e-07 30.4 0.3 1.6 1 1 1 2 2 2 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.6 EGO30217.1 - 0.027 14.6 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain GrpB PF04229.14 EGO30218.1 - 0.07 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 GrpB protein Tet_JBP PF12851.7 EGO30218.1 - 0.16 11.3 1.8 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily ROKNT PF08067.11 EGO30218.1 - 0.16 12.2 3.0 0.62 10.4 3.0 2.0 1 1 0 1 1 1 0 ROKNT (NUC014) domain ANAPC4 PF12896.7 EGO30219.1 - 1.2e-32 113.0 0.1 2.4e-32 112.1 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PINIT PF14324.6 EGO30223.1 - 2.7e-38 131.6 0.1 4.7e-38 130.8 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EGO30223.1 - 4.9e-18 64.6 6.8 9e-18 63.8 6.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGO30223.1 - 9.8e-07 28.5 1.0 2.3e-06 27.3 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EGO30223.1 - 0.0044 16.7 0.8 0.03 14.1 0.0 2.6 3 0 0 3 3 3 1 SAP domain Prok-RING_4 PF14447.6 EGO30223.1 - 0.053 13.4 1.9 0.15 12.0 1.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CBM_26 PF16824.5 EGO30225.1 - 0.046 13.9 0.1 0.079 13.1 0.1 1.4 1 1 0 1 1 1 0 C-terminal carbohydrate-binding module BAR_3 PF16746.5 EGO30225.1 - 0.078 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 BAR domain of APPL family PheRS_DBD2 PF18554.1 EGO30225.1 - 0.079 13.0 1.4 0.15 12.1 1.4 1.5 1 0 0 1 1 1 0 PheRS DNA binding domain 2 ATG101 PF07855.12 EGO30225.1 - 0.58 10.1 3.0 0.77 9.7 3.0 1.2 1 1 0 1 1 1 0 Autophagy-related protein 101 TTSSLRR PF12468.8 EGO30226.1 - 1.7 8.9 4.3 20 5.5 0.7 2.8 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein DUF1192 PF06698.11 EGO30227.1 - 0.14 12.2 2.1 0.27 11.3 0.1 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Sec1 PF00995.23 EGO30229.1 - 3.6e-123 412.8 0.0 4.1e-123 412.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3349 PF11829.8 EGO30229.1 - 0.065 14.0 0.0 0.31 11.9 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Plavaka PF18759.1 EGO30230.1 - 2.9e-12 46.5 0.1 2.9e-12 46.5 0.1 2.1 3 0 0 3 3 3 1 Plavaka transposase GCD14 PF08704.10 EGO30230.1 - 0.2 11.3 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Voldacs PF03517.13 EGO30232.1 - 0.027 14.6 2.1 0.031 14.4 2.1 1.0 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling gag_pre-integrs PF13976.6 EGO30233.1 - 1.3e-09 37.8 0.4 1.6e-09 37.5 0.4 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Esterase PF00756.20 EGO30235.1 - 3.5e-40 138.2 0.0 4.1e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGO30235.1 - 0.0053 16.3 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGO30235.1 - 0.017 14.4 0.1 0.049 12.9 0.1 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGO30235.1 - 0.025 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Pkinase PF00069.25 EGO30236.1 - 1e-63 215.2 0.1 1.3e-63 214.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30236.1 - 2.7e-19 69.5 0.0 4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO30236.1 - 1e-07 32.1 0.1 2.9e-06 27.4 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO30236.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO30236.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGO30236.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Retrotran_gag_2 PF14223.6 EGO30239.1 - 9.1e-13 48.1 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 EGO30239.1 - 0.092 12.5 1.6 0.17 11.6 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1771 PF08590.10 EGO30239.1 - 0.095 13.1 1.2 0.18 12.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) PCB_OB PF17092.5 EGO30241.1 - 0.063 14.0 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Retrotrans_gag PF03732.17 EGO30243.1 - 0.00053 20.2 0.1 0.00083 19.6 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Bromodomain PF00439.25 EGO30245.1 - 5.5e-35 119.3 0.1 3.3e-17 62.3 0.1 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EGO30245.1 - 2.3e-18 66.1 1.6 5.6e-18 64.9 1.6 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation WD40 PF00400.32 EGO30245.1 - 2.4e-15 56.6 12.4 0.00091 20.0 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGO30245.1 - 0.00019 20.5 0.1 0.014 14.3 0.0 2.8 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EGO30245.1 - 0.00065 20.0 0.0 3.3 8.1 0.0 4.6 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO30245.1 - 0.11 12.4 0.3 7.4 6.4 0.0 3.6 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF2555 PF10742.9 EGO30245.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Retrotrans_gag PF03732.17 EGO30250.1 - 4.1e-07 30.2 3.1 7.5e-07 29.4 2.1 2.0 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO30251.1 - 4.7e-05 23.3 1.4 9e-05 22.4 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO30251.1 - 0.00014 21.8 5.3 0.00021 21.2 5.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO30251.1 - 0.025 14.1 0.9 0.047 13.2 0.9 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain CDC50 PF03381.15 EGO30252.1 - 0.077 12.5 0.1 0.086 12.3 0.1 1.0 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family TehB PF03848.14 EGO30254.1 - 0.093 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Drc1-Sld2 PF11719.8 EGO30255.1 - 8.9e-14 51.9 0.8 8.9e-14 51.9 0.8 2.2 2 1 0 2 2 2 1 DNA replication and checkpoint protein PCI PF01399.27 EGO30257.1 - 1.5e-16 60.8 0.0 1.4e-15 57.6 0.0 2.5 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EGO30257.1 - 9.1e-05 22.5 0.9 0.00021 21.3 0.9 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Utp12 PF04003.12 EGO30257.1 - 0.043 14.1 0.8 0.14 12.5 0.1 2.2 2 1 0 2 2 2 0 Dip2/Utp12 Family SPARC_Ca_bdg PF10591.9 EGO30258.1 - 0.41 11.0 7.8 0.74 10.1 7.8 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region gag-asp_proteas PF13975.6 EGO30264.1 - 7.6e-05 23.2 0.0 0.00013 22.4 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO30264.1 - 0.00045 20.8 0.0 0.00063 20.3 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO30264.1 - 0.002 17.9 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Siva PF05458.12 EGO30264.1 - 0.13 11.9 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Metallophos PF00149.28 EGO30265.1 - 5.2e-39 134.9 0.0 2.5e-38 132.6 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO30265.1 - 1.1e-17 64.2 0.0 1.9e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Fungal_trans PF04082.18 EGO30267.1 - 1.3e-25 90.0 0.0 9.8e-25 87.1 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO30267.1 - 2.9e-05 24.1 7.2 5.8e-05 23.1 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S19 PF06756.11 EGO30267.1 - 2.2 8.3 5.8 0.28 11.2 0.2 2.4 3 0 0 3 3 3 0 Chorion protein S19 C-terminal DUF3684 PF12449.8 EGO30271.1 - 0.014 13.3 0.1 0.015 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Dsl1_N PF11988.8 EGO30271.1 - 0.15 11.0 0.5 0.39 9.7 0.1 1.7 1 1 1 2 2 2 0 Retrograde transport protein Dsl1 N terminal DUF4413 PF14372.6 EGO30272.1 - 0.00029 21.1 2.3 0.0012 19.2 2.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) Complex1_30kDa PF00329.19 EGO30274.1 - 1.2e-47 161.6 0.0 1.6e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PHD PF00628.29 EGO30275.1 - 0.0014 18.5 0.6 0.0036 17.2 0.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-FPG_IleRS PF06827.14 EGO30275.1 - 0.036 13.9 2.2 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS KDZ PF18758.1 EGO30277.1 - 1.4e-16 60.8 4.5 1.2e-15 57.7 0.2 3.2 2 1 2 4 4 4 2 Kyakuja-Dileera-Zisupton transposase Xlink PF00193.17 EGO30277.1 - 0.011 16.1 1.2 0.03 14.7 0.4 2.1 2 0 0 2 2 2 0 Extracellular link domain HTH_23 PF13384.6 EGO30278.1 - 0.00015 21.5 0.1 0.0002 21.0 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EGO30278.1 - 0.075 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 EGO30278.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 EGO30278.1 - 0.16 12.1 0.1 0.67 10.1 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L15e PF00827.17 EGO30279.1 - 2.5e-90 301.4 10.4 2.8e-90 301.2 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L13 PF00572.18 EGO30281.1 - 1.9e-12 47.5 0.6 1.5e-10 41.4 0.1 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 DEAD PF00270.29 EGO30282.1 - 8.8e-09 35.4 0.0 1.8e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ribosomal_L33 PF00471.20 EGO30282.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L33 Insulin_TMD PF17870.1 EGO30282.1 - 1.4 9.0 4.6 1.2 9.3 1.4 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4820 PF16091.5 EGO30283.1 - 0.45 9.8 7.2 1.3 8.4 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PGA2 PF07543.12 EGO30283.1 - 0.5 10.3 9.3 0.27 11.2 2.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DCP2 PF05026.13 EGO30286.1 - 4.4e-32 110.2 2.2 7.9e-32 109.4 2.2 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGO30286.1 - 5.3e-15 55.6 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF2063 PF09836.9 EGO30289.1 - 0.05 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain W2 PF02020.18 EGO30289.1 - 0.077 13.1 0.9 0.12 12.5 0.3 1.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Pex16 PF08610.10 EGO30290.1 - 1.6e-90 303.6 2.4 1.8e-90 303.4 2.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) gag_pre-integrs PF13976.6 EGO30292.1 - 3.7e-09 36.3 0.1 5.8e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 EGO30292.1 - 0.089 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain Glyco_transf_21 PF13506.6 EGO30296.1 - 8.3e-25 87.2 2.7 5.2e-19 68.4 0.2 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGO30296.1 - 7e-16 58.8 0.0 9.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGO30296.1 - 0.0003 20.8 0.7 0.00065 19.7 0.7 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO30296.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 V_ATPase_I PF01496.19 EGO30297.1 - 0.88 7.4 4.3 1.2 7.0 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRKG1_interact PF15898.5 EGO30297.1 - 1.1 10.2 11.2 0.17 12.8 6.6 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1980 PF09323.10 EGO30301.1 - 0.12 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF1091 PF06477.13 EGO30305.1 - 0.033 14.6 0.1 3.6 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) RPN5_C PF18098.1 EGO30306.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain SepF PF04472.12 EGO30306.1 - 0.16 12.3 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Cell division protein SepF Yippee-Mis18 PF03226.14 EGO30307.1 - 1.5e-16 60.5 0.0 1.7e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Urocanase PF01175.18 EGO30308.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain KDZ PF18758.1 EGO30309.1 - 1.6e-32 112.9 0.3 3.7e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 EGO30312.1 - 4.3e-36 124.6 1.4 5.8e-34 117.6 1.4 2.4 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase GTP_EFTU PF00009.27 EGO30314.1 - 1e-56 191.6 0.6 1.6e-56 190.9 0.6 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO30314.1 - 3.7e-27 94.8 0.0 8.3e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGO30314.1 - 1.4e-17 63.8 3.7 3.8e-17 62.5 3.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO30314.1 - 3.6e-05 23.8 0.1 7.4e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO30314.1 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase PduV-EutP PF10662.9 EGO30314.1 - 0.0048 16.7 0.2 2 8.2 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGO30314.1 - 0.011 15.3 0.3 0.022 14.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L32e PF01655.18 EGO30317.1 - 7.2e-48 161.5 0.7 8.4e-48 161.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Sin3a_C PF16879.5 EGO30319.1 - 4.5e-84 282.6 0.2 3.5e-83 279.6 0.0 2.5 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 EGO30319.1 - 7.6e-41 138.0 12.6 1e-17 63.9 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGO30319.1 - 4.1e-39 132.6 0.1 8.5e-39 131.6 0.1 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor Zn-C2H2_12 PF18112.1 EGO30319.1 - 0.03 14.8 0.0 0.086 13.3 0.0 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain GBP_C PF02841.14 EGO30319.1 - 1.5 8.2 3.5 0.49 9.8 0.2 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Baculo_19 PF04798.12 EGO30320.1 - 0.0081 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Baculovirus 19 kDa protein conserved region DUF5595 PF18077.1 EGO30320.1 - 0.15 12.2 2.4 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) zf-CCHC_3 PF13917.6 EGO30321.1 - 4.3e-06 26.6 2.8 9.5e-06 25.5 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO30321.1 - 6.2e-06 26.0 5.1 9.3e-06 25.5 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle DDE_Tnp_4 PF13359.6 EGO30323.1 - 6.1e-21 74.7 0.1 8.3e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 EGO30323.1 - 0.0051 16.4 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein ABC_membrane_3 PF13748.6 EGO30323.1 - 0.19 11.0 0.3 0.27 10.4 0.3 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region NOA36 PF06524.12 EGO30324.1 - 0.31 10.3 6.3 0.36 10.1 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein NTP_transf_3 PF12804.7 EGO30325.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain IF4E PF01652.18 EGO30326.1 - 2.3e-50 170.5 0.0 3.6e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SF3A2 PF16835.5 EGO30327.1 - 6.6e-36 122.6 0.2 1e-35 122.0 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGO30327.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGO30327.1 - 0.014 15.3 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EGO30327.1 - 0.019 14.5 0.8 0.036 13.6 0.8 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DDE_3 PF13358.6 EGO30329.1 - 2e-12 47.1 0.0 5e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 EGO30330.1 - 0.0066 16.1 0.3 0.33 10.6 0.1 2.4 2 0 0 2 2 2 2 Winged helix-turn helix Picorna_P3A PF06363.11 EGO30330.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein KDZ PF18758.1 EGO30331.1 - 7e-12 45.4 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Plavaka PF18759.1 EGO30332.1 - 5.8e-18 65.2 0.1 7.5e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Retrotrans_gag PF03732.17 EGO30333.1 - 0.0048 17.1 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO30333.1 - 0.0057 16.7 4.3 0.0092 16.0 4.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Peptidase_M60_C PF18630.1 EGO30333.1 - 0.047 13.8 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain DUF4939 PF16297.5 EGO30333.1 - 0.13 12.2 1.3 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) zf-CCHC_2 PF13696.6 EGO30333.1 - 0.72 9.7 4.7 1.3 8.9 4.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EGO30333.1 - 1.1 9.0 4.0 2.8 7.7 4.0 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger gag-asp_proteas PF13975.6 EGO30334.1 - 3e-07 30.9 0.0 4.8e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO30334.1 - 1.3e-06 28.2 0.0 1.8e-06 27.8 0.0 1.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGO30334.1 - 5.9e-06 26.8 0.0 7.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 EGO30334.1 - 0.025 14.4 0.0 0.028 14.2 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease Pollen_Ole_e_I PF01190.17 EGO30334.1 - 0.027 14.8 0.2 2.6 8.5 0.0 2.0 1 1 1 2 2 2 0 Pollen proteins Ole e I like Peptidase_U4 PF03419.13 EGO30334.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA zf-CCHC PF00098.23 EGO30336.1 - 4.7e-08 32.8 5.9 1.1e-07 31.6 5.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30336.1 - 1.5e-05 25.2 2.2 2.6e-05 24.4 0.3 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein RNase_H PF00075.24 EGO30336.1 - 0.03 14.5 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 RNase H zf-CCHC_3 PF13917.6 EGO30336.1 - 1.2 9.2 8.4 0.48 10.4 5.6 1.8 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 EGO30337.1 - 1.6e-07 31.0 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Retrotran_gag_2 PF14223.6 EGO30338.1 - 3.2e-14 52.8 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO30338.1 - 8.9e-05 22.1 0.1 0.00015 21.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGO30338.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.6 EGO30339.1 - 8.6e-07 29.4 0.0 1e-06 29.2 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO30339.1 - 3.5e-06 27.6 0.0 4.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO30339.1 - 1.9e-05 24.5 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO30341.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO30341.1 - 0.0013 19.4 0.0 0.0023 18.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO30341.1 - 0.048 13.4 0.2 6.3 6.6 0.0 2.1 1 1 1 2 2 2 0 Retroviral aspartyl protease AAA_35 PF14516.6 EGO30342.1 - 0.18 10.6 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain HTH_Tnp_Tc3_2 PF01498.18 EGO30343.1 - 4.4e-11 42.9 1.5 4.4e-11 42.9 1.5 1.5 2 0 0 2 2 2 1 Transposase LexA_DNA_bind PF01726.16 EGO30343.1 - 0.021 14.6 0.3 0.79 9.5 0.1 2.3 1 1 0 2 2 2 0 LexA DNA binding domain Retrotrans_gag PF03732.17 EGO30345.1 - 0.033 14.5 0.2 0.072 13.4 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 EGO30345.1 - 0.078 13.1 1.9 0.14 12.2 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3145 PF11343.8 EGO30345.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) R2K_2 PF18299.1 EGO30345.1 - 0.079 12.8 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 zf-CCHC_2 PF13696.6 EGO30345.1 - 0.21 11.4 2.7 0.35 10.7 2.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Nop53 PF07767.11 EGO30350.1 - 8.2e-93 311.9 7.8 9.6e-93 311.7 7.8 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) NACHT_N PF17100.5 EGO30350.1 - 4.2 7.2 5.9 1.3 8.9 2.5 1.8 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase DUF4718 PF15842.5 EGO30351.1 - 0.089 12.6 1.6 0.12 12.2 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) zf-CCHC_4 PF14392.6 EGO30351.1 - 0.69 9.7 4.6 1.1 9.0 4.6 1.3 1 0 0 1 1 1 0 Zinc knuckle ThrE PF06738.12 EGO30355.1 - 3.1e-40 138.0 8.6 4.2e-40 137.6 8.6 1.1 1 0 0 1 1 1 1 Putative threonine/serine exporter SNF2_N PF00176.23 EGO30356.1 - 3.9e-70 236.3 0.0 7.8e-70 235.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO30356.1 - 5.4e-14 52.5 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EGO30356.1 - 0.0043 17.0 5.1 0.011 15.7 5.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EGO30356.1 - 0.043 13.8 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGO30356.1 - 0.82 9.6 9.5 0.055 13.4 4.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HTH_OrfB_IS605 PF12323.8 EGO30359.1 - 0.036 13.6 0.1 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FYDLN_acid PF09538.10 EGO30359.1 - 0.35 11.6 2.8 2.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4422 PF14393.6 EGO30360.1 - 0.017 15.0 0.6 0.023 14.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) TF_AP-2 PF03299.14 EGO30360.1 - 0.16 11.9 1.1 0.22 11.5 1.1 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 Myb_DNA-bind_4 PF13837.6 EGO30362.1 - 0.00047 20.5 0.0 0.0012 19.2 0.0 1.6 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGO30362.1 - 0.00071 20.5 0.0 0.00097 20.1 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Nbas_N PF15492.6 EGO30363.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal PPR_2 PF13041.6 EGO30366.1 - 5.3e-05 23.3 0.0 0.0019 18.3 0.0 2.4 1 1 1 2 2 2 1 PPR repeat family PPR PF01535.20 EGO30366.1 - 0.068 13.5 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 PPR repeat MCM2_N PF12619.8 EGO30368.1 - 0.0069 16.7 9.2 0.008 16.5 8.7 1.5 1 1 0 1 1 1 1 Mini-chromosome maintenance protein 2 DTHCT PF08070.11 EGO30368.1 - 0.19 12.5 6.4 1.6 9.5 6.5 2.1 1 1 0 1 1 1 0 DTHCT (NUC029) region TFIIA PF03153.13 EGO30370.1 - 0.2 11.6 15.1 0.23 11.4 15.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transposase_21 PF02992.14 EGO30372.1 - 0.00081 18.7 0.1 0.0012 18.2 0.1 1.2 1 0 0 1 1 1 1 Transposase family tnp2 HSP70 PF00012.20 EGO30373.1 - 1.7e-30 105.8 0.0 2e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein AP4E_app_platf PF14807.6 EGO30374.1 - 0.0053 17.1 0.8 0.0072 16.7 0.3 1.6 1 1 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HMG_box PF00505.19 EGO30374.1 - 0.0055 17.1 0.4 0.013 15.9 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box SH3-WW_linker PF16618.5 EGO30374.1 - 0.017 15.6 2.4 0.019 15.4 2.4 1.1 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 HMG_box_2 PF09011.10 EGO30374.1 - 0.029 14.9 0.3 0.029 14.9 0.3 1.7 2 0 0 2 2 2 0 HMG-box domain Sporozoite_P67 PF05642.11 EGO30374.1 - 0.23 9.5 6.2 0.24 9.4 6.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Plavaka PF18759.1 EGO30377.1 - 2e-15 56.8 0.1 2.7e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF659 PF04937.15 EGO30378.1 - 8.2e-13 48.5 0.4 8.2e-13 48.5 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) CRT10 PF08728.10 EGO30378.1 - 0.025 12.8 0.3 0.059 11.5 0.1 1.4 1 1 0 1 1 1 0 CRT10 SMP PF04927.12 EGO30378.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Seed maturation protein BCAS2 PF05700.11 EGO30379.1 - 4.3e-43 147.4 2.0 5.3e-43 147.1 2.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_3 PF13415.6 EGO30382.1 - 2.7e-30 104.0 13.3 4.6e-07 30.0 0.1 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO30382.1 - 2.6e-29 100.7 5.7 5.5e-06 26.2 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGO30382.1 - 5.6e-29 99.9 15.7 1.5e-07 31.3 1.5 6.3 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGO30382.1 - 2.1e-28 97.6 3.7 3.5e-08 33.5 0.3 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGO30382.1 - 2.5e-28 97.4 3.8 2.6e-06 26.9 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGO30382.1 - 9.5e-22 76.1 8.8 0.00066 19.6 0.1 6.6 6 0 0 6 6 6 5 Kelch motif TPR_MLP1_2 PF07926.12 EGO30382.1 - 0.0017 18.4 15.5 0.0017 18.4 15.5 7.8 4 3 4 8 8 6 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EGO30382.1 - 0.0019 18.7 34.9 0.0028 18.1 20.7 5.5 3 1 2 5 5 4 2 Fez1 KxDL PF10241.9 EGO30382.1 - 0.0055 16.9 2.2 0.0055 16.9 2.2 7.1 5 1 1 6 6 6 2 Uncharacterized conserved protein ZapB PF06005.12 EGO30382.1 - 0.28 11.7 0.1 0.28 11.7 0.1 8.1 8 0 0 8 8 8 0 Cell division protein ZapB RNaseH_like PF04308.12 EGO30382.1 - 0.5 10.3 1.9 1.3 8.9 0.4 2.2 2 0 0 2 2 2 0 Ribonuclease H-like Retrotrans_gag PF03732.17 EGO30383.1 - 3.7e-08 33.5 0.2 3.7e-08 33.5 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Cytokin_check_N PF10407.9 EGO30384.1 - 0.74 9.8 3.2 17 5.4 0.3 2.6 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus zf-CCHC_4 PF14392.6 EGO30389.1 - 0.61 9.9 4.6 1 9.1 4.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C32 PF05411.12 EGO30392.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF4939 PF16297.5 EGO30394.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EGO30394.1 - 0.12 12.5 0.8 0.2 11.8 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_2 PF08914.11 EGO30395.1 - 3.1e-10 40.1 0.5 8.4e-10 38.7 0.5 1.8 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EGO30395.1 - 2.4e-07 31.1 0.0 0.0034 17.8 0.0 2.8 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain SurA_N PF09312.11 EGO30395.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 SurA N-terminal domain Rap1-DNA-bind PF09197.10 EGO30395.1 - 2.7 8.6 6.7 2.7 8.6 2.9 2.8 2 1 0 2 2 2 0 Rap1, DNA-binding DUF2615 PF11027.8 EGO30396.1 - 0.053 13.7 0.8 0.12 12.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Methyltransf_8 PF05148.15 EGO30399.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase PEP-utilisers_N PF05524.13 EGO30399.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal CSD2 PF17876.1 EGO30400.1 - 0.0058 16.8 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 Cold shock domain U5_2-snRNA_bdg PF10597.9 EGO30400.1 - 0.11 12.6 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 Forkhead PF00250.18 EGO30402.1 - 5.3e-19 68.3 0.0 1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain DUF4200 PF13863.6 EGO30402.1 - 0.37 11.2 4.6 0.6 10.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AT_hook PF02178.19 EGO30402.1 - 6.7 6.9 21.0 0.93 9.6 0.5 3.5 3 0 0 3 3 3 0 AT hook motif 6PGD PF00393.19 EGO30404.1 - 5.7e-125 416.5 0.0 7.6e-125 416.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGO30404.1 - 5e-50 169.8 0.0 7.3e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGO30404.1 - 0.0032 18.0 0.0 0.0074 16.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGO30404.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EGO30404.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EGO30404.1 - 0.055 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 EGO30404.1 - 0.1 12.2 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ras PF00071.22 EGO30405.1 - 2e-54 183.5 0.0 2.3e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO30405.1 - 3.7e-21 75.6 0.0 5.1e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO30405.1 - 3.7e-06 26.5 0.0 5.6e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO30405.1 - 0.0055 16.3 0.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain zf-CCHC PF00098.23 EGO30408.1 - 3.7e-07 29.9 4.6 7.5e-07 29.0 4.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30408.1 - 5.7e-06 26.5 0.4 5.7e-06 26.5 0.4 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO30408.1 - 0.11 12.5 0.4 0.32 11.0 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGO30411.1 - 5.7e-07 29.4 1.3 5.9e-07 29.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO30411.1 - 4.1e-06 26.6 5.1 5.3e-06 26.3 5.1 1.2 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.18 EGO30411.1 - 0.015 14.7 1.0 0.024 14.1 1.0 1.5 1 1 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGO30411.1 - 0.051 13.3 1.9 0.073 12.8 1.9 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EGO30412.1 - 0.068 12.9 1.6 0.14 11.9 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-RING_10 PF16685.5 EGO30412.1 - 5.5 7.2 12.7 15 5.8 12.7 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 gag_pre-integrs PF13976.6 EGO30413.1 - 3.5e-08 33.2 0.1 5.4e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain Rabaptin PF03528.15 EGO30415.1 - 0.025 13.3 0.3 0.035 12.8 0.3 1.2 1 0 0 1 1 1 0 Rabaptin Actin PF00022.19 EGO30417.1 - 1.2e-127 426.0 0.0 6e-127 423.6 0.0 1.8 1 1 0 1 1 1 1 Actin WD40 PF00400.32 EGO30418.1 - 4e-31 106.6 14.3 2.8e-07 31.1 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO30418.1 - 1e-09 38.6 0.2 0.16 12.3 0.1 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGO30418.1 - 0.00083 19.0 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.16 EGO30418.1 - 0.002 16.7 0.0 0.66 8.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 EGO30418.1 - 0.062 13.3 0.6 6 6.9 0.2 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HTH_23 PF13384.6 EGO30419.1 - 0.00039 20.1 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Plavaka PF18759.1 EGO30421.1 - 2.6e-17 63.1 0.0 4.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Retrotrans_gag PF03732.17 EGO30422.1 - 2.2e-09 37.5 0.7 9.4e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO30422.1 - 0.00061 19.8 4.6 0.0013 18.7 4.6 1.6 1 0 0 1 1 1 1 Zinc knuckle GerPC PF10737.9 EGO30422.1 - 0.095 12.8 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Spore germination protein GerPC gag_pre-integrs PF13976.6 EGO30423.1 - 1.2e-10 41.1 0.8 2e-10 40.4 0.7 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 EGO30424.1 - 0.13 12.0 0.6 0.13 12.0 0.6 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 EGO30424.1 - 0.18 11.6 3.1 0.34 10.7 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle V-SNARE_C PF12352.8 EGO30425.1 - 2e-10 40.8 0.9 3.4e-10 40.0 0.3 1.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGO30425.1 - 0.1 12.5 0.2 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Sec20 Retrotrans_gag PF03732.17 EGO30431.1 - 1.3e-06 28.6 1.6 1.3e-06 28.6 1.6 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 EGO30431.1 - 0.029 14.2 0.1 0.083 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) BrnA_antitoxin PF14384.6 EGO30431.1 - 0.39 11.3 3.0 0.93 10.0 0.0 2.8 3 0 0 3 3 3 0 BrnA antitoxin of type II toxin-antitoxin system Cyclin_N PF00134.23 EGO30433.1 - 3.9e-38 130.1 0.3 7.6e-38 129.1 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO30433.1 - 2.5e-07 30.8 0.3 6.9e-07 29.4 0.3 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4364 PF14277.6 EGO30433.1 - 0.0013 18.5 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) DUF4838 PF16126.5 EGO30433.1 - 0.0053 16.2 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) PGM_PMM_I PF02878.16 EGO30440.1 - 1.1e-18 67.3 0.5 6.1e-08 32.5 0.1 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGO30440.1 - 1.8e-12 47.3 0.2 3.5e-11 43.1 0.2 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EGO30440.1 - 0.0093 16.6 0.1 0.11 13.1 0.1 2.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGO30440.1 - 0.072 13.3 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1793 PF08760.11 EGO30440.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) gag-asp_proteas PF13975.6 EGO30441.1 - 0.11 13.0 0.0 0.2 12.3 0.0 1.6 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.6 EGO30442.1 - 0.024 14.4 1.6 0.04 13.7 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF5550 PF17704.1 EGO30443.1 - 0.04 14.0 0.5 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5550) VPS13_mid_rpt PF16910.5 EGO30444.1 - 3.7e-79 265.5 1.1 5.7e-74 248.5 0.0 5.0 5 0 0 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EGO30444.1 - 6e-79 265.2 1.8 7.1e-74 248.6 0.1 3.8 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGO30444.1 - 1.2e-69 233.6 7.9 4.9e-66 221.9 0.1 3.2 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGO30444.1 - 1.7e-58 198.2 0.0 4.9e-52 177.0 0.0 3.2 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGO30444.1 - 1.9e-27 95.7 0.0 1.6e-26 92.7 0.0 2.7 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGO30444.1 - 1.7e-09 37.9 0.1 4.9e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain NUDE_C PF04880.13 EGO30447.1 - 0.00065 20.2 24.8 0.00065 20.2 24.8 5.0 2 1 2 4 4 4 1 NUDE protein, C-terminal conserved region DUF2353 PF09789.9 EGO30447.1 - 0.24 10.7 20.8 0.19 11.0 9.4 2.5 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) RHIM PF12721.7 EGO30447.1 - 0.4 11.2 2.9 0.54 10.8 0.0 2.8 3 0 0 3 3 3 0 RIP homotypic interaction motif DUF4407 PF14362.6 EGO30447.1 - 1.3 8.3 6.0 0.59 9.4 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 EGO30447.1 - 2.8 8.9 23.0 0.16 12.9 7.1 3.1 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 EGO30447.1 - 3.2 7.8 22.1 7.3 6.7 12.0 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EGO30447.1 - 6.2 7.0 26.7 0.19 11.9 10.2 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 EGO30447.1 - 7.3 7.1 19.2 0.55 10.7 0.1 3.8 4 0 0 4 4 4 0 Cell division protein ZapB MIP-T3_C PF17749.1 EGO30447.1 - 8.8 6.3 13.9 1 9.3 4.0 3.4 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Retrotran_gag_2 PF14223.6 EGO30449.1 - 8.3e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ribosomal_S9 PF00380.19 EGO30450.1 - 1.8e-30 105.9 0.1 2.1e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.22 EGO30451.1 - 1.9e-54 184.3 0.0 2.2e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family zf-CCHC PF00098.23 EGO30453.1 - 2.7e-08 33.5 1.6 5.5e-08 32.5 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30453.1 - 0.013 15.8 5.5 0.013 15.8 5.5 2.8 2 2 0 2 2 2 0 Retrotransposon gag protein A_thal_3526 PF09713.10 EGO30453.1 - 0.088 13.1 0.1 4.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) gag_pre-integrs PF13976.6 EGO30454.1 - 6.3e-11 42.0 0.2 9.6e-11 41.4 0.2 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain HTH_23 PF13384.6 EGO30455.1 - 3.6e-08 33.0 0.1 4.9e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EGO30455.1 - 0.0025 17.8 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 EGO30455.1 - 0.0029 17.2 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 EGO30455.1 - 0.0032 17.6 0.2 0.0065 16.6 0.2 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 EGO30455.1 - 0.0059 16.1 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_Tnp_ISL3 PF13542.6 EGO30455.1 - 0.0071 15.7 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 EGO30455.1 - 0.01 15.4 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 EGO30455.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EGO30455.1 - 0.019 15.3 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Transposase NUMOD1 PF07453.13 EGO30455.1 - 0.023 14.9 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 NUMOD1 domain HTH_38 PF13936.6 EGO30455.1 - 0.065 13.0 1.1 0.083 12.7 1.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 EGO30455.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor SK_channel PF03530.14 EGO30456.1 - 0.0062 16.5 0.4 0.018 15.0 0.4 1.8 1 0 0 1 1 1 1 Calcium-activated SK potassium channel HemY_N PF07219.13 EGO30456.1 - 5 7.4 5.4 3.7 7.8 0.2 2.8 3 0 0 3 3 3 0 HemY protein N-terminus SPRY PF00622.28 EGO30460.1 - 0.0067 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF5314 PF17241.2 EGO30462.1 - 0.043 13.5 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DUF4219 PF13961.6 EGO30462.1 - 0.044 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) SYCE1 PF15233.6 EGO30463.1 - 0.0012 19.0 3.4 0.0017 18.5 3.4 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 PXB PF12828.7 EGO30463.1 - 0.0014 18.7 1.0 0.003 17.6 1.0 1.7 1 1 0 1 1 1 1 PX-associated DUF5082 PF16888.5 EGO30463.1 - 0.0031 17.8 1.5 0.0042 17.4 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) YscO PF07321.12 EGO30463.1 - 0.0094 15.9 3.1 0.011 15.6 3.1 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO BRE1 PF08647.11 EGO30463.1 - 0.011 15.7 6.9 0.017 15.2 6.9 1.4 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 EGO30463.1 - 0.019 15.6 1.5 0.025 15.2 1.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EGO30463.1 - 0.019 15.4 8.9 0.14 12.7 6.8 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Fmp27_WPPW PF10359.9 EGO30463.1 - 0.037 12.9 2.0 0.046 12.6 2.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain JIP_LZII PF16471.5 EGO30463.1 - 0.052 13.7 4.1 1.4 9.2 0.8 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Dzip-like_N PF13815.6 EGO30463.1 - 0.18 11.8 4.1 0.25 11.3 4.1 1.3 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal KLRAQ PF10205.9 EGO30463.1 - 0.19 12.0 5.9 0.3 11.4 5.9 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein HALZ PF02183.18 EGO30463.1 - 1.6 9.0 7.6 0.1 12.8 2.1 2.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper Ribosomal_S28e PF01200.18 EGO30464.1 - 4.7e-31 106.6 1.3 5.2e-31 106.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Plavaka PF18759.1 EGO30466.1 - 1.5e-13 50.7 0.2 2.1e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase CDC45 PF02724.14 EGO30469.1 - 0.0039 15.6 2.1 0.0065 14.8 1.8 1.4 2 0 0 2 2 2 1 CDC45-like protein SepF PF04472.12 EGO30469.1 - 0.18 12.1 0.0 0.54 10.6 0.0 1.7 1 0 0 1 1 1 0 Cell division protein SepF DUF4854 PF16146.5 EGO30471.1 - 0.079 13.3 0.0 0.083 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Tape_meas_lam_C PF09718.10 EGO30472.1 - 0.062 13.4 0.3 0.087 13.0 0.3 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) zf-CCHC PF00098.23 EGO30474.1 - 7.1e-06 25.9 2.7 1.7e-05 24.7 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO30474.1 - 0.002 18.0 3.0 0.0059 16.6 3.0 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30474.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_6 PF15288.6 EGO30474.1 - 0.032 14.1 0.6 0.065 13.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGO30474.1 - 0.037 13.9 0.7 0.069 13.0 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle NADH_Oxid_Nqo15 PF11497.8 EGO30476.1 - 0.07 13.2 0.2 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 RhoGAP PF00620.27 EGO30477.1 - 0.028 14.2 0.3 0.19 11.5 0.0 2.4 3 1 0 3 3 3 0 RhoGAP domain DUF1904 PF08921.11 EGO30477.1 - 0.12 12.7 0.0 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) RPN5_C PF18098.1 EGO30478.1 - 0.053 13.6 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain PA26 PF04636.13 EGO30478.1 - 0.15 11.0 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HTH_32 PF13565.6 EGO30479.1 - 0.017 15.7 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_33 PF13592.6 EGO30479.1 - 0.054 13.2 0.1 0.092 12.4 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix PIF1 PF05970.14 EGO30481.1 - 0.0022 17.2 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.18 EGO30481.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 EGO30481.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGO30481.1 - 0.044 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGO30481.1 - 0.072 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGO30481.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EGO30481.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EGO30481.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO30481.1 - 0.22 10.6 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Helitron_like_N PF14214.6 EGO30482.1 - 6.2e-24 85.3 0.1 3.9e-23 82.7 0.0 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PADR1 PF08063.12 EGO30482.1 - 0.14 11.9 0.2 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 PADR1 (NUC008) domain Cyclin_N PF00134.23 EGO30483.1 - 1.9e-27 95.5 1.6 2.1e-27 95.4 0.6 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO30483.1 - 2.5e-13 50.1 0.3 1.2e-12 47.9 0.0 2.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain DDE_3 PF13358.6 EGO30487.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EGO30488.1 - 0.00029 21.0 0.3 0.015 15.5 0.0 2.4 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.6 EGO30488.1 - 0.0058 16.6 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EGO30488.1 - 0.0064 16.6 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2236 PF09995.9 EGO30488.1 - 0.023 14.9 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF746 PF05344.11 EGO30488.1 - 0.046 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_23 PF13384.6 EGO30488.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 EGO30488.1 - 0.2 11.5 0.9 0.38 10.6 0.1 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain NIPSNAP PF07978.13 EGO30489.1 - 3.7e-32 110.6 2.0 6.1e-27 93.8 0.3 2.2 2 0 0 2 2 2 2 NIPSNAP Retrotrans_gag PF03732.17 EGO30490.1 - 1.8e-07 31.3 2.4 3e-07 30.6 0.0 2.6 4 0 0 4 4 4 1 Retrotransposon gag protein FAS_meander PF17951.1 EGO30490.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain ARGLU PF15346.6 EGO30493.1 - 0.0088 15.9 12.9 0.0088 15.9 12.9 3.0 2 1 0 2 2 2 1 Arginine and glutamate-rich 1 DUF4718 PF15842.5 EGO30493.1 - 0.27 11.0 7.2 0.19 11.5 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Rrn6 PF10214.9 EGO30493.1 - 0.37 9.2 2.5 7.4 4.9 2.5 2.0 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LMBR1 PF04791.16 EGO30493.1 - 1.1 8.0 4.6 1.3 7.8 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase_fungal PF17667.1 EGO30494.1 - 2.7e-06 26.4 0.0 0.0023 16.8 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 EGO30494.1 - 0.0093 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family TerB_C PF15615.6 EGO30495.1 - 0.068 13.5 0.1 0.068 13.5 0.1 1.7 2 0 0 2 2 2 0 TerB-C domain TipAS PF07739.13 EGO30495.1 - 0.14 12.7 0.8 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF3450 PF11932.8 EGO30495.1 - 0.59 9.4 7.1 0.059 12.7 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 EGO30495.1 - 1.4 9.3 6.3 3.5 8.0 2.7 2.4 1 1 0 2 2 2 0 TSC-22/dip/bun family TFIIA PF03153.13 EGO30496.1 - 2.5 8.0 17.3 2.1 8.3 13.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CBS PF00571.28 EGO30498.1 - 2.9e-32 110.9 5.2 6e-09 36.2 0.0 4.7 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 EGO30498.1 - 2.1e-09 37.2 0.0 4.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TF_Otx PF03529.13 EGO30498.1 - 0.15 12.5 4.5 4.1 7.9 1.9 2.8 2 0 0 2 2 2 0 Otx1 transcription factor Myb_DNA-bind_3 PF12776.7 EGO30499.1 - 0.0085 17.1 1.4 0.03 15.3 0.2 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Bap31_Bap29_C PF18035.1 EGO30499.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Vfa1 PF08432.10 EGO30500.1 - 0.68 10.2 9.5 0.31 11.3 4.4 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 EGO30500.1 - 1.2 7.6 3.8 1.6 7.2 3.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDE_1 PF03184.19 EGO30501.1 - 7e-08 32.3 0.1 9.9e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DS PF01916.17 EGO30501.1 - 0.034 13.4 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Deoxyhypusine synthase NinD PF17466.2 EGO30502.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function zf-CCHC PF00098.23 EGO30503.1 - 0.0001 22.2 4.2 0.00023 21.1 4.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO30503.1 - 0.00067 19.4 5.7 0.0016 18.2 5.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30503.1 - 0.0024 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EGO30504.1 - 0.002 18.7 0.0 0.0026 18.4 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO30504.1 - 0.0023 18.5 0.0 0.0056 17.2 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EGO30504.1 - 0.0095 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Pal1 PF08316.11 EGO30505.1 - 0.05 14.3 0.8 0.073 13.8 0.1 1.6 2 0 0 2 2 2 0 Pal1 cell morphology protein DUF4278 PF14105.6 EGO30510.1 - 0.16 12.5 0.4 0.21 12.1 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4278) WD40 PF00400.32 EGO30513.1 - 2.2e-15 56.8 15.5 0.004 18.0 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EGO30513.1 - 0.095 11.3 0.1 0.87 8.1 0.0 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGO30513.1 - 1.5 7.2 6.8 4.8 5.6 0.2 3.6 3 1 0 4 4 4 0 Cytochrome D1 heme domain DUF3201 PF11447.8 EGO30515.1 - 0.031 13.8 0.3 0.073 12.6 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3201) DUF2264 PF10022.9 EGO30515.1 - 0.039 13.0 0.6 0.048 12.7 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) SlyX PF04102.12 EGO30515.1 - 0.089 13.4 0.8 0.15 12.7 0.8 1.4 1 0 0 1 1 1 0 SlyX zinc-ribbons_6 PF07191.12 EGO30516.1 - 0.03 14.3 1.8 2 8.4 0.0 2.2 2 1 0 2 2 2 0 zinc-ribbons WD40 PF00400.32 EGO30521.1 - 4.5e-07 30.5 0.3 1.5e-05 25.6 0.0 3.0 2 1 1 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO30521.1 - 3.8e-05 23.9 0.0 0.0019 18.4 0.0 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 EGO30521.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat Adaptin_binding PF10199.9 EGO30522.1 - 0.91 10.1 10.0 2.4 8.8 10.0 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BAH PF01426.18 EGO30528.1 - 0.0017 18.2 0.0 0.0069 16.2 0.0 2.0 1 1 0 1 1 1 1 BAH domain MNE1 PF13762.6 EGO30529.1 - 0.11 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component PHD PF00628.29 EGO30530.1 - 4.4e-10 39.3 6.3 4.4e-10 39.3 6.3 2.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EGO30530.1 - 9 6.0 11.4 0.44 10.1 2.9 3.0 3 0 0 3 3 3 0 PHD-finger LSM PF01423.22 EGO30531.1 - 6.9e-18 64.1 0.2 1e-17 63.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGO30531.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Hfq protein zf-ribbon_3 PF13248.6 EGO30535.1 - 1.7 8.2 12.5 1.5 8.4 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DUF4218 PF13960.6 EGO30536.1 - 0.092 12.4 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Fibrinogen_aC PF12160.8 EGO30537.1 - 0.096 12.5 0.3 0.32 10.9 0.0 1.9 1 1 0 2 2 2 0 Fibrinogen alpha C domain Pkinase PF00069.25 EGO30538.1 - 2.1e-11 43.7 0.0 4.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30538.1 - 0.004 16.5 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_bind PF08675.11 EGO30538.1 - 0.0067 16.4 0.1 8.5 6.5 0.0 3.3 2 2 1 3 3 3 2 RNA binding domain Ima1_N PF09779.9 EGO30539.1 - 3.7e-34 118.5 3.4 5.6e-34 117.9 3.4 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain zinc_ribbon_9 PF14369.6 EGO30539.1 - 2 8.7 9.2 8.7 6.7 5.1 2.8 2 0 0 2 2 2 0 zinc-ribbon DUF1938 PF09153.10 EGO30541.1 - 0.0062 16.6 0.2 0.01 15.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1938) Paz_1 PF18349.1 EGO30541.1 - 0.024 14.6 0.3 0.04 13.9 0.3 1.3 1 0 0 1 1 1 0 PAZ domain PYRIN PF02758.16 EGO30541.1 - 0.11 12.7 0.3 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain zinc_ribbon_2 PF13240.6 EGO30543.1 - 2.4 8.0 7.3 0.46 10.3 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2321 PF10083.9 EGO30546.1 - 0.0081 15.8 0.0 0.0089 15.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) Myb_DNA-bind_3 PF12776.7 EGO30547.1 - 0.0018 19.2 0.0 0.0051 17.8 0.0 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Ras PF00071.22 EGO30549.1 - 2e-50 170.6 0.1 2.3e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO30549.1 - 3.6e-18 65.9 0.0 5.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO30549.1 - 5.3e-05 22.7 0.0 5.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO30549.1 - 0.0011 18.5 0.0 0.0035 16.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO30549.1 - 0.0071 16.3 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase RepB PF07506.11 EGO30549.1 - 0.026 14.6 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein MMR_HSR1 PF01926.23 EGO30549.1 - 0.039 14.0 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase PF06745.13 EGO30549.1 - 0.13 11.5 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EGO30549.1 - 0.16 11.7 0.1 0.56 9.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain DDE_1 PF03184.19 EGO30550.1 - 1.6e-10 40.9 0.0 1.1e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease zf-CCCH PF00642.24 EGO30555.1 - 1.1e-19 69.8 13.9 3.4e-11 42.8 2.8 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGO30555.1 - 2.2e-09 36.9 11.0 1.4e-06 28.0 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGO30555.1 - 4e-09 36.2 13.8 8.4e-07 28.8 3.9 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 EGO30555.1 - 0.0035 17.8 8.2 0.035 14.6 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EGO30555.1 - 0.02 15.6 9.7 0.28 11.9 1.7 2.4 1 1 1 2 2 2 0 Torus domain Defensin_int PF17858.1 EGO30555.1 - 0.094 12.7 3.6 0.29 11.1 1.3 2.3 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide INCENP_ARK-bind PF03941.15 EGO30557.1 - 5.3e-20 71.1 0.7 8.1e-20 70.5 0.7 1.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF4381 PF14316.6 EGO30558.1 - 0.097 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CxC2 PF18803.1 EGO30560.1 - 2.1e-14 53.6 1.5 2.6e-14 53.3 0.4 1.7 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGO30560.1 - 6.6e-14 52.1 0.4 4.7e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase ApoLp-III PF07464.11 EGO30561.1 - 0.021 14.9 0.1 0.033 14.3 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Plavaka PF18759.1 EGO30562.1 - 3e-66 223.9 8.1 1.9e-24 86.5 0.2 4.2 1 1 3 4 4 4 4 Plavaka transposase RVP_2 PF08284.11 EGO30563.1 - 4.3e-06 26.5 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO30563.1 - 2.6e-05 24.7 0.0 3.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO30563.1 - 0.00057 20.5 0.0 0.00076 20.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.6 EGO30564.1 - 0.059 13.4 4.9 0.16 12.0 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Zn_Tnp_IS91 PF14319.6 EGO30564.1 - 0.14 12.2 3.4 0.36 10.9 3.4 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain CTXphi_pIII-N1 PF16710.5 EGO30564.1 - 0.21 11.7 0.8 7.9 6.6 0.6 2.5 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII HTH_32 PF13565.6 EGO30567.1 - 0.083 13.5 0.1 0.14 12.8 0.0 1.4 2 0 0 2 2 2 0 Homeodomain-like domain Myb_DNA-bind_3 PF12776.7 EGO30570.1 - 0.0044 18.0 0.0 0.0075 17.2 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Auxin_repressed PF05564.12 EGO30570.1 - 0.13 12.9 1.0 2.8 8.7 0.2 2.3 2 0 0 2 2 2 0 Dormancy/auxin associated protein Plavaka PF18759.1 EGO30571.1 - 1.1e-49 169.4 0.1 1.8e-49 168.7 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Cas3_C PF18395.1 EGO30573.1 - 0.16 12.4 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Cas3 C-terminal domain zf-HC2 PF13490.6 EGO30573.1 - 0.9 9.8 5.1 1.7 8.9 5.1 1.6 1 0 0 1 1 1 0 Putative zinc-finger Pantoate_ligase PF02569.15 EGO30574.1 - 2.8 7.1 5.6 8.2 5.6 5.6 1.7 1 1 0 1 1 1 0 Pantoate-beta-alanine ligase TB2_DP1_HVA22 PF03134.19 EGO30576.1 - 1.9e-07 30.9 0.9 5.6e-07 29.4 0.0 1.8 1 1 1 2 2 2 2 TB2/DP1, HVA22 family TMEM237 PF15383.6 EGO30576.1 - 0.06 12.4 0.0 0.067 12.3 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 Sec3_C PF09763.9 EGO30577.1 - 3.3e-143 478.6 5.9 1.4e-132 443.5 3.1 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EGO30577.1 - 4.5e-19 68.4 0.0 9.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Rab5-bind PF09311.11 EGO30577.1 - 0.022 14.2 3.7 0.019 14.4 1.8 1.8 2 0 0 2 2 2 0 Rabaptin-like protein LytTR PF04397.15 EGO30577.1 - 0.048 13.9 0.3 0.18 12.1 0.2 2.0 2 0 0 2 2 2 0 LytTr DNA-binding domain DDE_1 PF03184.19 EGO30578.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP-grasp_2 PF08442.10 EGO30579.1 - 1.3e-69 233.9 0.4 2.6e-69 232.9 0.4 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGO30579.1 - 3e-24 85.6 0.1 5.5e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGO30579.1 - 3.6e-12 46.2 0.2 7.7e-12 45.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EGO30579.1 - 0.0046 16.8 0.0 0.032 14.0 0.0 2.2 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EGO30579.1 - 0.014 14.9 0.4 0.091 12.2 0.1 2.3 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EGO30579.1 - 0.087 12.4 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Retrotran_gag_2 PF14223.6 EGO30581.1 - 3.8e-10 39.6 0.1 5.3e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGO30581.1 - 0.049 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Helitron_like_N PF14214.6 EGO30584.1 - 1.2e-08 35.4 0.0 1.4e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Ribosomal_S17_N PF16205.5 EGO30587.1 - 4.9e-29 100.5 0.4 8.8e-29 99.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGO30587.1 - 2.9e-26 91.3 0.9 4.8e-26 90.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 DUF922 PF06037.11 EGO30587.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Peptidase_S9_N PF02897.15 EGO30592.1 - 0.073 11.9 0.1 0.095 11.5 0.1 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Retrotrans_gag PF03732.17 EGO30593.1 - 0.002 18.4 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Sigma54_AID PF00309.20 EGO30594.1 - 0.019 14.8 0.5 0.035 14.0 0.5 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) DDE_1 PF03184.19 EGO30597.1 - 1.1e-18 67.5 0.0 2.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EGO30597.1 - 8.3e-07 28.9 0.2 9.4e-06 25.4 0.2 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L17 PF01196.19 EGO30598.1 - 0.14 13.1 0.3 12 6.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L17 KDZ PF18758.1 EGO30599.1 - 3.3e-42 144.6 0.2 9.3e-42 143.1 0.2 1.7 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PemK_toxin PF02452.17 EGO30601.1 - 0.019 15.4 0.3 0.061 13.7 0.0 2.0 2 0 0 2 2 2 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system MFMR_assoc PF16596.5 EGO30601.1 - 0.12 12.8 8.1 0.081 13.4 3.6 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR CBFB_NFYA PF02045.15 EGO30601.1 - 0.13 12.9 0.1 0.13 12.9 0.1 2.6 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MCM PF00493.23 EGO30603.1 - 1e-94 315.9 0.2 1.5e-94 315.3 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO30603.1 - 6.8e-34 116.4 0.1 1.3e-33 115.5 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO30603.1 - 2.6e-23 82.3 0.3 5.1e-23 81.3 0.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO30603.1 - 1.7e-14 54.2 0.1 4.8e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO30603.1 - 2.9e-08 33.4 0.2 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGO30603.1 - 0.003 17.4 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO30603.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ANAPC_CDC26 PF10471.9 EGO30603.1 - 0.22 12.4 2.4 45 5.0 2.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Retrotran_gag_2 PF14223.6 EGO30604.1 - 1.8e-08 34.2 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVP_2 PF08284.11 EGO30605.1 - 0.011 15.5 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease CDC50 PF03381.15 EGO30605.1 - 0.081 12.4 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family DDE_1 PF03184.19 EGO30606.1 - 1.2e-05 25.0 0.1 2.1e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease gag_pre-integrs PF13976.6 EGO30608.1 - 2.6e-10 40.0 0.0 4.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EGO30609.1 - 3.3e-08 33.3 1.6 6.5e-08 32.3 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30609.1 - 9.5e-05 22.6 2.7 0.00044 20.5 2.7 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein T2SSG PF08334.11 EGO30609.1 - 0.097 12.8 0.1 0.47 10.6 0.0 2.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G Retrotrans_gag PF03732.17 EGO30610.1 - 0.021 15.1 0.1 0.049 13.9 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4939 PF16297.5 EGO30610.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) TRP_2 PF08344.11 EGO30610.1 - 0.067 13.4 1.3 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Transient receptor ion channel II Plavaka PF18759.1 EGO30613.1 - 3.5e-122 407.7 0.1 5e-122 407.2 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Nucleoporin_N PF08801.11 EGO30616.1 - 1.1e-59 202.3 0.4 1.7e-59 201.7 0.4 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGO30616.1 - 4.7e-31 108.2 0.0 4.1e-30 105.1 0.0 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Chromo PF00385.24 EGO30617.1 - 3.8e-09 36.3 0.1 5e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 EGO30618.1 - 2.8e-07 30.5 0.3 3.1e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain PHR PF08005.12 EGO30618.1 - 0.059 14.0 0.0 0.061 14.0 0.0 1.0 1 0 0 1 1 1 0 PHR domain eIF2A PF08662.11 EGO30620.1 - 4e-41 141.0 0.9 2.4e-37 128.7 0.0 4.4 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGO30620.1 - 9.5e-05 22.6 0.5 35 4.8 0.0 6.5 6 2 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO30620.1 - 0.064 14.1 6.6 0.73 10.8 0.1 5.1 7 0 0 7 7 7 0 WD domain, G-beta repeat zf-CCHC_4 PF14392.6 EGO30621.1 - 0.081 12.7 1.6 0.14 11.9 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 EGO30625.1 - 0.016 15.9 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 EGO30625.1 - 0.14 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 EGO30628.1 - 1.3e-05 24.8 0.2 1.9e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HycA_repressor PF11046.8 EGO30628.1 - 0.079 13.2 0.4 0.16 12.2 0.2 1.6 2 0 0 2 2 2 0 Transcriptional repressor of hyc and hyp operons MoaC PF01967.21 EGO30629.1 - 2.2e-47 160.5 0.3 3.6e-47 159.9 0.3 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EGO30629.1 - 1.8e-38 131.4 0.0 3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGO30629.1 - 2.2e-24 86.7 0.0 3.7e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGO30629.1 - 1.9e-05 24.9 0.0 7.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGO30629.1 - 0.0071 16.5 0.0 0.027 14.6 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain RNA_pol_Rpb1_4 PF05000.17 EGO30629.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Chitin_synth_2 PF03142.15 EGO30630.1 - 5.8e-10 38.4 0.6 1.5e-09 37.0 0.1 1.7 1 1 0 2 2 2 1 Chitin synthase Arc_C PF18162.1 EGO30630.1 - 0.013 15.3 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 Arc C-lobe Pal1 PF08316.11 EGO30632.1 - 3.7e-15 56.9 1.9 5.5e-15 56.3 0.3 2.4 3 1 0 3 3 3 1 Pal1 cell morphology protein OTOS PF15182.6 EGO30633.1 - 0.058 13.3 1.1 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 Otospiralin DUF1771 PF08590.10 EGO30634.1 - 0.038 14.4 0.9 0.071 13.5 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Pol_alpha_B_N PF08418.10 EGO30634.1 - 0.047 13.7 1.1 0.057 13.4 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-CCHC_4 PF14392.6 EGO30634.1 - 0.081 12.7 1.6 0.14 11.9 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4718 PF15842.5 EGO30634.1 - 3.2 7.5 7.6 0.85 9.4 3.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) gag_pre-integrs PF13976.6 EGO30635.1 - 5.6e-09 35.7 0.1 8.6e-09 35.1 0.1 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain DENN PF02141.21 EGO30639.1 - 6.6e-18 65.3 0.0 1.4e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain YabA PF06156.13 EGO30639.1 - 5.6 7.7 12.4 15 6.3 0.1 3.4 3 0 0 3 3 3 0 Initiation control protein YabA Retrotran_gag_2 PF14223.6 EGO30640.1 - 0.033 13.9 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Gal11_ABD1 PF18535.1 EGO30640.1 - 0.084 13.0 0.3 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) SNARE PF05739.19 EGO30641.1 - 3.9e-12 46.0 0.5 3.6e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EGO30641.1 - 6.7e-06 25.9 9.5 3.2e-05 23.7 0.3 2.5 2 1 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 EGO30641.1 - 8.6e-05 21.6 0.1 8.6e-05 21.6 0.1 2.5 3 0 0 3 3 3 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 EGO30641.1 - 0.00028 21.1 0.1 0.00028 21.1 0.1 2.7 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.16 EGO30641.1 - 0.15 12.5 0.4 0.15 12.5 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 EGO30641.1 - 0.91 9.9 5.9 0.37 11.1 0.2 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EGO30641.1 - 5.3 7.6 7.4 3.3 8.2 1.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3316 PF11777.8 EGO30644.1 - 0.12 12.4 0.1 0.15 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) M11L PF11099.8 EGO30646.1 - 0.062 13.6 1.4 0.095 13.0 1.4 1.5 1 1 0 1 1 1 0 Apoptosis regulator M11L like Pkinase PF00069.25 EGO30647.1 - 1.2e-50 172.3 0.0 3.2e-49 167.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30647.1 - 7e-23 81.2 0.0 1.2e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DRIM PF07539.12 EGO30648.1 - 4.5e-06 25.3 0.0 7.2e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 Down-regulated in metastasis MFS_1 PF07690.16 EGO30648.1 - 2.4e-05 23.4 15.5 0.0011 18.0 15.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO30648.1 - 0.029 13.2 2.9 0.057 12.3 2.9 1.4 1 0 0 1 1 1 0 Sugar (and other) transporter DDE_Tnp_4 PF13359.6 EGO30651.1 - 6.2e-28 97.5 0.0 7.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGO30651.1 - 4.8e-08 32.9 0.1 3.4e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain BUD22 PF09073.10 EGO30653.1 - 0.0017 17.8 4.9 0.0017 17.8 4.9 1.0 1 0 0 1 1 1 1 BUD22 DNA_pol_phi PF04931.13 EGO30653.1 - 0.0041 15.3 13.0 0.0042 15.3 13.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi RRN3 PF05327.11 EGO30653.1 - 0.0042 15.7 8.1 0.0048 15.5 8.1 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 PRTP PF01366.18 EGO30653.1 - 0.0079 14.3 0.3 0.0088 14.1 0.3 1.1 1 0 0 1 1 1 1 Herpesvirus processing and transport protein FYDLN_acid PF09538.10 EGO30653.1 - 0.0091 16.7 11.2 0.013 16.1 11.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) CobT PF06213.12 EGO30653.1 - 0.011 15.2 8.8 0.012 15.0 8.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 EGO30653.1 - 0.015 13.6 10.1 0.014 13.6 10.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF5523 PF17661.1 EGO30653.1 - 0.016 14.9 6.0 0.018 14.7 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) MRNIP PF15749.5 EGO30653.1 - 0.017 15.8 2.4 0.018 15.7 2.4 1.1 1 0 0 1 1 1 0 MRN-interacting protein Sigma70_ner PF04546.13 EGO30653.1 - 0.026 14.4 8.0 0.029 14.3 8.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CPSF100_C PF13299.6 EGO30653.1 - 0.029 14.6 0.7 0.03 14.5 0.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 EGO30653.1 - 0.037 13.4 10.4 0.036 13.5 10.4 1.1 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 EGO30653.1 - 0.04 13.8 2.2 0.046 13.6 2.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 EGO30653.1 - 0.057 13.2 6.8 0.069 12.9 6.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 EGO30653.1 - 0.062 12.4 16.6 0.062 12.4 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF913 PF06025.12 EGO30653.1 - 0.062 12.3 0.4 0.064 12.2 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RXT2_N PF08595.11 EGO30653.1 - 0.15 12.1 8.0 0.19 11.7 8.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP_sp32 PF07222.12 EGO30653.1 - 0.15 11.5 5.6 0.19 11.1 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.14 EGO30653.1 - 0.16 10.2 9.3 0.18 10.1 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 EGO30653.1 - 0.25 10.3 6.7 0.26 10.2 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4820 PF16091.5 EGO30653.1 - 0.27 10.6 2.2 0.29 10.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 EGO30653.1 - 0.35 10.0 6.3 0.4 9.8 6.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFB6 PF17110.5 EGO30653.1 - 0.36 10.6 6.3 0.42 10.3 6.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Astro_capsid_p PF12226.8 EGO30653.1 - 0.64 9.1 10.0 0.8 8.8 10.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pes-10 PF07149.11 EGO30653.1 - 1.1 8.2 12.5 1.3 8.0 12.5 1.1 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 EGO30653.1 - 1.3 8.3 17.7 1.6 8.0 17.7 1.1 1 0 0 1 1 1 0 NOA36 protein WRNPLPNID PF15017.6 EGO30653.1 - 1.7 9.6 15.4 3.1 8.7 15.4 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box FAM176 PF14851.6 EGO30653.1 - 2 8.1 12.2 3.4 7.3 12.2 1.5 1 1 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 EGO30653.1 - 7.2 4.6 9.4 11 4.0 9.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.8 EGO30653.1 - 8.1 6.6 21.3 11 6.2 21.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 COPI_C PF06957.11 EGO30653.1 - 9 4.9 8.4 9.6 4.8 8.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus RhoGEF PF00621.20 EGO30655.1 - 3.5e-43 148.0 0.0 5.3e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 EGO30655.1 - 1.3e-07 31.3 6.0 0.00022 20.9 1.3 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGO30655.1 - 0.0025 18.2 5.1 0.62 10.6 0.2 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO30655.1 - 2.1 9.2 7.9 57 4.9 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat BEN PF10523.9 EGO30656.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 BEN domain DUF469 PF04320.14 EGO30656.1 - 0.16 12.8 0.0 0.18 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein with unknown function (DUF469) RVP_2 PF08284.11 EGO30657.1 - 0.00072 19.3 0.0 0.00087 19.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EGO30657.1 - 0.046 14.3 0.0 0.084 13.4 0.0 1.5 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 EGO30658.1 - 7.5e-07 29.0 1.9 1.4e-06 28.1 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30658.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein ARGLU PF15346.6 EGO30661.1 - 0.0018 18.2 12.4 0.0021 18.0 12.4 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 SIR2 PF02146.17 EGO30661.1 - 0.024 14.6 0.3 0.034 14.1 0.3 1.2 1 0 0 1 1 1 0 Sir2 family EMC3_TMCO1 PF01956.16 EGO30661.1 - 0.033 13.9 4.5 0.039 13.7 4.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3523 PF12037.8 EGO30661.1 - 0.059 12.7 12.1 0.065 12.6 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Radial_spoke_3 PF06098.11 EGO30661.1 - 0.085 12.1 12.3 0.094 12.0 12.3 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 Cdh1_DBD_1 PF18196.1 EGO30661.1 - 0.13 12.6 6.3 0.16 12.3 6.3 1.0 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF4795 PF16043.5 EGO30661.1 - 0.16 11.6 9.3 0.19 11.3 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) RBM39linker PF15519.6 EGO30661.1 - 0.26 12.4 4.1 0.34 12.0 4.1 1.1 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Connexin PF00029.19 EGO30661.1 - 0.3 10.8 2.9 0.31 10.8 2.9 1.0 1 0 0 1 1 1 0 Connexin LMBR1 PF04791.16 EGO30661.1 - 0.31 9.9 2.2 0.35 9.7 2.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein RPN2_C PF18004.1 EGO30661.1 - 0.63 9.9 10.2 0.74 9.7 10.2 1.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MCU PF04678.13 EGO30661.1 - 0.65 10.1 6.2 0.74 9.9 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter U1snRNP70_N PF12220.8 EGO30661.1 - 0.84 10.3 7.1 1.1 9.9 7.1 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Coilin_N PF15862.5 EGO30661.1 - 2.2 8.1 9.2 2.6 7.8 9.2 1.1 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 EGO30661.1 - 2.6 6.7 5.6 2.7 6.7 5.6 1.0 1 0 0 1 1 1 0 Presenilin DNA_pol3_a_NII PF11490.8 EGO30661.1 - 9.9 6.1 14.5 13 5.7 14.5 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PIF1 PF05970.14 EGO30662.1 - 1.7e-10 40.6 0.1 3e-10 39.8 0.0 1.5 1 1 1 2 2 2 1 PIF1-like helicase WBS_methylT PF12589.8 EGO30662.1 - 0.87 10.4 7.3 1.2 9.9 7.3 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome gag-asp_proteas PF13975.6 EGO30663.1 - 5e-06 27.0 0.0 7.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO30663.1 - 0.00083 20.0 0.0 0.0012 19.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EGO30663.1 - 0.0041 16.9 0.1 0.019 14.7 0.1 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 EGO30664.1 - 4e-08 33.0 5.9 9.7e-08 31.8 5.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30664.1 - 0.00013 22.2 0.2 0.00013 22.2 0.2 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO30664.1 - 0.85 9.6 8.0 0.45 10.5 5.4 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4 PF00097.25 EGO30665.1 - 1.3e-09 37.7 9.1 2.4e-09 36.9 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO30665.1 - 8.3e-08 32.5 10.6 1.4e-07 31.7 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO30665.1 - 1.8e-07 31.0 12.0 3.5e-07 30.1 5.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO30665.1 - 3e-07 30.2 8.6 1.4e-06 28.0 8.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO30665.1 - 1.4e-06 28.1 5.6 2.6e-06 27.2 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO30665.1 - 6.8e-05 22.7 7.2 0.00012 21.9 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGO30665.1 - 0.00018 21.6 10.6 0.00037 20.6 10.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGO30665.1 - 0.00029 20.6 6.2 0.00061 19.6 6.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGO30665.1 - 0.0077 16.5 6.0 0.017 15.4 6.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO30665.1 - 0.016 15.3 1.9 0.029 14.4 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 EGO30665.1 - 0.023 14.4 8.1 0.051 13.3 8.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGO30665.1 - 0.033 14.0 6.4 0.067 13.0 6.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.11 EGO30665.1 - 0.72 9.7 2.5 6.7 6.6 0.2 2.5 2 0 0 2 2 2 0 GAGA factor TerY_C PF15616.6 EGO30665.1 - 1.2 9.2 3.6 2.5 8.2 3.6 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_11 PF17123.5 EGO30665.1 - 6 6.7 12.1 1.8 8.4 4.9 2.6 2 1 0 2 2 2 0 RING-like zinc finger TTSSLRR PF12468.8 EGO30668.1 - 0.15 12.3 0.5 29 5.0 0.6 2.7 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Cyclin_N PF00134.23 EGO30669.1 - 7e-40 135.7 3.1 3e-39 133.7 1.1 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO30669.1 - 7.5e-19 68.0 0.1 1.9e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Plavaka PF18759.1 EGO30670.1 - 1.6e-38 132.8 0.0 4.6e-35 121.4 0.0 2.5 2 1 0 2 2 2 1 Plavaka transposase NAD_Gly3P_dh_C PF07479.14 EGO30671.1 - 1.7e-51 174.2 0.1 2.6e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EGO30671.1 - 1.5e-32 112.8 0.0 2.6e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EGO30671.1 - 6.8e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EGO30671.1 - 8.2e-06 26.3 0.0 2.7e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 EGO30671.1 - 0.0068 16.9 0.1 7.6 7.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGO30671.1 - 0.031 14.3 0.0 0.097 12.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EGO30671.1 - 0.035 14.3 0.0 0.094 12.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EGO30671.1 - 0.088 13.1 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGO30671.1 - 0.14 12.4 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AIF_C PF14721.6 EGO30677.1 - 0.35 11.2 2.5 0.21 12.0 0.5 1.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Retrotran_gag_2 PF14223.6 EGO30678.1 - 0.00034 20.3 0.0 0.00035 20.3 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Tet_JBP PF12851.7 EGO30681.1 - 0.66 9.3 3.6 0.91 8.8 0.0 2.4 2 1 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily EcoR124_C PF12008.8 EGO30682.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Ssl1 PF04056.14 EGO30682.1 - 0.027 14.3 0.4 0.039 13.8 0.4 1.2 1 0 0 1 1 1 0 Ssl1-like Adaptin_N PF01602.20 EGO30686.1 - 5.5e-121 404.7 6.8 6.6e-121 404.4 6.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGO30686.1 - 1.7e-36 124.9 0.0 3.3e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGO30686.1 - 1.6e-13 50.9 0.0 3.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cauli_VI PF01693.16 EGO30689.1 - 1e-06 29.0 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-CGNR PF11706.8 EGO30689.1 - 0.042 13.7 1.2 0.042 13.7 1.2 2.3 2 0 0 2 2 2 0 CGNR zinc finger KDZ PF18758.1 EGO30690.1 - 0.00052 19.7 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Chromo PF00385.24 EGO30692.1 - 0.013 15.4 0.4 0.019 14.9 0.0 1.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_M60_C PF18630.1 EGO30693.1 - 0.015 15.4 0.0 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain Med5 PF08689.10 EGO30694.1 - 1.8e-09 36.1 0.2 1.8e-09 36.1 0.2 2.1 2 1 0 2 2 2 1 Mediator complex subunit Med5 Proteasome PF00227.26 EGO30698.1 - 7.4e-37 126.7 0.0 8.4e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 EGO30698.1 - 0.048 13.8 0.0 0.76 9.9 0.1 2.5 3 0 0 3 3 3 0 Phage late-transcription coactivator CxC2 PF18803.1 EGO30700.1 - 3e-22 78.8 0.2 1.2e-21 76.8 0.1 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGO30700.1 - 3.2e-18 66.2 3.5 4.7e-18 65.6 1.6 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGO30700.1 - 1.8e-07 31.2 0.1 4.8e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Hydrolase_4 PF12146.8 EGO30704.1 - 2.5e-08 33.5 0.1 4.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO30704.1 - 2.7e-06 27.2 0.4 1.6e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold SepF PF04472.12 EGO30706.1 - 0.04 14.2 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Cell division protein SepF DUF1351 PF07083.11 EGO30707.1 - 0.12 12.1 0.2 0.15 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Zn_clus PF00172.18 EGO30710.1 - 6.5e-08 32.6 5.0 9.1e-08 32.1 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Retrotrans_gag PF03732.17 EGO30711.1 - 3.4e-05 24.0 2.5 7.9e-05 22.9 0.0 2.7 1 1 1 2 2 2 1 Retrotransposon gag protein GMP_synt_C PF00958.22 EGO30712.1 - 0.0075 16.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 2 GMP synthase C terminal domain DUF1068 PF06364.12 EGO30715.1 - 0.074 12.9 0.4 0.076 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Septin PF00735.18 EGO30721.1 - 3.6e-109 364.4 0.8 4.1e-109 364.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGO30721.1 - 2.1e-06 27.8 0.0 5.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO30721.1 - 0.0013 18.4 0.3 0.048 13.2 0.1 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO30721.1 - 0.0014 18.5 0.7 0.04 13.8 0.6 2.9 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGO30721.1 - 0.0067 16.5 2.5 1.9 8.5 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EGO30721.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.18 EGO30721.1 - 0.027 13.8 0.2 0.06 12.7 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 EGO30721.1 - 0.095 11.7 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EGO30721.1 - 0.14 12.6 0.7 0.7 10.4 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Roc PF08477.13 EGO30721.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Transposase_21 PF02992.14 EGO30722.1 - 0.0076 15.5 0.1 0.0085 15.4 0.1 1.0 1 0 0 1 1 1 1 Transposase family tnp2 TGT PF01702.18 EGO30724.1 - 0.085 12.0 1.0 0.099 11.8 1.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase TFIIA PF03153.13 EGO30726.1 - 0.67 9.9 17.2 0.79 9.7 17.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM70 PF14967.6 EGO30726.1 - 10 5.5 7.2 16 4.8 7.2 1.3 1 0 0 1 1 1 0 FAM70 protein zinc_ribbon_2 PF13240.6 EGO30728.1 - 1.9 8.3 9.0 0.36 10.6 0.8 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 EGO30730.1 - 0.046 14.6 1.2 0.12 13.3 0.8 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGO30730.1 - 0.13 12.6 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon PGAP1 PF07819.13 EGO30731.1 - 1.5e-07 31.4 1.1 1.6e-07 31.3 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EGO30731.1 - 3.2e-05 23.9 0.0 5.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGO30731.1 - 0.00032 20.4 0.3 0.0054 16.4 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EGO30731.1 - 0.00068 19.2 0.1 0.0018 17.8 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGO30731.1 - 0.00096 19.8 1.8 0.0013 19.3 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EGO30731.1 - 0.002 17.5 0.0 0.0077 15.6 0.0 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EGO30731.1 - 0.0081 15.5 0.7 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LCAT PF02450.15 EGO30731.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 EGO30731.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) GspH PF12019.8 EGO30732.1 - 0.0085 16.5 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Type II transport protein GspH RVT_2 PF07727.14 EGO30733.1 - 1.7e-08 34.4 0.1 1.9e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.27 EGO30734.1 - 1.7e-67 226.7 0.2 2.4e-67 226.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGO30734.1 - 3.1e-33 114.1 0.0 2.3e-32 111.3 0.0 2.5 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 EGO30734.1 - 1.2e-21 76.5 0.0 2.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO30734.1 - 1.1e-12 48.1 0.0 3.3e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGO30734.1 - 2e-12 47.0 0.0 6.2e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGO30734.1 - 0.00027 21.0 0.2 0.00058 19.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase HTH_Tnp_Tc3_2 PF01498.18 EGO30737.1 - 2.6e-09 37.2 1.7 3.3e-09 36.9 0.4 1.9 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 EGO30737.1 - 2.9e-05 23.7 0.0 0.00021 21.0 0.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain SapB_2 PF03489.17 EGO30737.1 - 0.021 15.0 0.3 0.093 12.9 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 2 HTH_7 PF02796.15 EGO30737.1 - 0.047 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Trp_repressor PF01371.19 EGO30737.1 - 0.082 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Trp repressor protein HTH_23 PF13384.6 EGO30737.1 - 0.1 12.4 0.0 0.83 9.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.6 EGO30737.1 - 0.12 12.8 0.2 10 6.7 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain DUF5127 PF17168.4 EGO30739.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) DDE_Tnp_4 PF13359.6 EGO30740.1 - 0.092 12.4 0.0 0.093 12.4 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Ribonucleas_3_3 PF14622.6 EGO30741.1 - 2.9e-07 30.7 0.0 4.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EGO30741.1 - 1.8e-06 28.5 0.1 3.6e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EGO30741.1 - 0.0039 17.8 0.2 0.011 16.4 0.2 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Chibby PF14645.6 EGO30742.1 - 0.23 11.9 0.1 0.27 11.6 0.1 1.2 1 0 0 1 1 1 0 Chibby family Myco_arth_vir_N PF09610.10 EGO30743.1 - 1 9.5 3.9 1.5 8.9 3.9 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) RRM_1 PF00076.22 EGO30746.1 - 7.8e-40 134.5 0.1 2.5e-20 72.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGO30746.1 - 7.1e-14 52.7 1.9 3e-12 47.4 1.9 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 EGO30746.1 - 0.00012 22.1 0.2 0.0081 16.2 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 EGO30746.1 - 0.00065 19.5 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EGO30746.1 - 0.08 12.5 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_3 PF12776.7 EGO30752.1 - 1.2e-08 35.8 2.6 0.0008 20.3 0.5 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Di19_C PF14571.6 EGO30752.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal TRAM1 PF08390.11 EGO30754.1 - 0.068 12.8 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 TRAM1-like protein GYF PF02213.16 EGO30756.1 - 5.6e-15 54.7 0.0 1.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EGO30756.1 - 0.03 14.1 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 GYF domain 2 KDZ PF18758.1 EGO30757.1 - 1.8e-38 132.4 0.0 3.6e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF1349 PF07081.11 EGO30757.1 - 0.11 12.2 0.1 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1349) Mito_fiss_reg PF05308.11 EGO30761.1 - 0.14 12.3 0.7 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Plavaka PF18759.1 EGO30762.1 - 7.1e-11 41.9 1.1 1.1e-10 41.3 1.1 1.3 1 0 0 1 1 1 1 Plavaka transposase RhoGEF PF00621.20 EGO30762.1 - 0.23 11.7 2.9 0.26 11.5 1.8 1.7 1 1 0 1 1 1 0 RhoGEF domain zf-CCHC_3 PF13917.6 EGO30764.1 - 0.24 11.4 9.6 0.42 10.6 9.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 EGO30765.1 - 1.8e-09 37.8 1.3 4.3e-09 36.5 0.3 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 EGO30765.1 - 2.3e-06 27.4 1.5 4.6e-06 26.4 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Plavaka PF18759.1 EGO30767.1 - 3.9e-14 52.6 0.1 1.9e-10 40.5 0.0 2.5 1 1 1 2 2 2 2 Plavaka transposase YlbD_coat PF14071.6 EGO30767.1 - 0.025 14.8 2.0 0.068 13.4 2.0 1.7 1 0 0 1 1 1 0 Putative coat protein Wbp11 PF09429.10 EGO30770.1 - 5.1e-19 68.4 7.6 8.7e-19 67.7 7.6 1.3 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 EGO30770.1 - 5e-13 49.6 11.4 5e-13 49.6 11.4 3.7 3 2 0 3 3 3 1 mRNA biogenesis factor NTNH_C PF08470.10 EGO30770.1 - 0.21 11.5 0.5 0.3 10.9 0.5 1.1 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal LodA_N PF17990.1 EGO30770.1 - 0.93 9.4 3.1 1.5 8.7 3.1 1.2 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal MULE PF10551.9 EGO30771.1 - 4.2e-11 43.1 0.0 1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain 3H PF02829.14 EGO30776.1 - 0.033 14.5 0.2 0.045 14.0 0.2 1.2 1 0 0 1 1 1 0 3H domain TPR_8 PF13181.6 EGO30776.1 - 0.074 13.3 1.1 0.27 11.5 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat S1 PF00575.23 EGO30779.1 - 2.7e-47 159.0 22.3 4.1e-12 46.3 0.0 9.3 10 0 0 10 10 10 7 S1 RNA binding domain TPR_14 PF13428.6 EGO30779.1 - 1.1e-08 35.1 2.0 0.14 13.0 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO30779.1 - 1.5e-06 28.6 0.0 0.2 12.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 EGO30779.1 - 0.00025 21.1 2.3 0.036 14.0 0.0 3.3 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) TPR_16 PF13432.6 EGO30779.1 - 0.00031 21.3 0.1 19 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EGO30779.1 - 0.0016 17.7 3.9 0.39 9.8 4.3 3.0 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 EGO30779.1 - 0.005 17.1 0.0 1.7 9.2 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO30779.1 - 0.0072 16.5 0.3 0.042 14.1 1.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGO30779.1 - 0.082 13.1 3.7 16 5.9 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGO30779.1 - 0.096 11.9 2.0 3.7 6.7 0.1 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO30779.1 - 0.27 11.5 5.1 7 7.0 0.3 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO30779.1 - 0.38 10.7 1.8 1.7 8.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Plavaka PF18759.1 EGO30780.1 - 5.2e-45 154.1 0.1 5.9e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 EGO30781.1 - 1.5e-27 96.7 0.1 2.6e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Trm56 PF01994.16 EGO30783.1 - 0.1 12.5 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 tRNA ribose 2'-O-methyltransferase, aTrm56 DoxD PF04173.13 EGO30783.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 TQO small subunit DoxD SUR7 PF06687.12 EGO30788.1 - 3 7.4 11.1 4.5 6.8 11.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family KDZ PF18758.1 EGO30789.1 - 9.8e-34 116.9 0.0 1.3e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Cut8 PF08559.10 EGO30793.1 - 1.8e-10 40.8 0.0 6e-08 32.6 0.0 2.9 2 1 0 2 2 2 2 Cut8, nuclear proteasome tether protein zf-C2H2 PF00096.26 EGO30795.1 - 0.036 14.5 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EGO30795.1 - 0.19 11.6 0.2 0.36 10.6 0.2 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Plavaka PF18759.1 EGO30797.1 - 3.1e-14 53.0 0.0 7.3e-08 32.0 0.0 2.4 1 1 1 2 2 2 2 Plavaka transposase DUF4579 PF15158.6 EGO30797.1 - 0.049 13.4 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) M11L PF11099.8 EGO30797.1 - 0.052 13.8 0.2 0.096 13.0 0.2 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11L like MTES_1575 PF18741.1 EGO30798.1 - 0.12 12.6 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 REase_MTES_1575 Helitron_like_N PF14214.6 EGO30800.1 - 1.5e-62 211.2 0.0 2.3e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus CDC50 PF03381.15 EGO30801.1 - 0.027 14.0 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_S78_2 PF14550.6 EGO30804.1 - 0.1 12.7 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Putative phage serine protease XkdF EMP24_GP25L PF01105.24 EGO30805.1 - 0.18 11.8 0.5 0.2 11.6 0.0 1.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD zf-RING_2 PF13639.6 EGO30806.1 - 7.7e-11 42.1 4.6 7.7e-11 42.1 4.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGO30806.1 - 2.1e-10 40.7 3.5 2.1e-10 40.7 3.5 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGO30806.1 - 2.6e-07 30.4 6.4 2.6e-07 30.4 6.4 2.6 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO30806.1 - 4.3e-07 29.7 3.6 4.3e-07 29.7 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGO30806.1 - 2.8e-06 27.3 0.3 5.9e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGO30806.1 - 2.9e-06 27.2 4.1 2.9e-06 27.2 4.1 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO30806.1 - 1.9e-05 24.5 2.3 1.9e-05 24.5 2.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGO30806.1 - 3.2e-05 23.6 3.6 0.0001 21.9 3.6 1.9 1 1 0 1 1 1 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 EGO30806.1 - 6.7e-05 23.1 1.6 6.7e-05 23.1 1.6 2.4 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_3 PF13920.6 EGO30806.1 - 0.001 18.9 1.7 0.001 18.9 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO30806.1 - 0.0093 15.8 3.2 0.0093 15.8 3.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGO30806.1 - 0.022 14.9 3.8 0.12 12.6 3.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain FYVE_2 PF02318.16 EGO30806.1 - 0.052 13.8 0.8 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 EGO30806.1 - 0.24 11.4 6.3 1.7 8.7 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 EGO30806.1 - 0.55 10.2 12.1 0.087 12.7 2.9 2.8 3 0 0 3 3 3 0 PHD-finger DUF1272 PF06906.11 EGO30806.1 - 0.63 10.2 7.8 1.9 8.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) HypA PF01155.19 EGO30806.1 - 0.82 9.7 4.5 5.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RINGv PF12906.7 EGO30806.1 - 7 6.9 9.1 7.2 6.8 2.5 2.6 2 1 0 2 2 2 0 RING-variant domain Zn_ribbon_17 PF17120.5 EGO30806.1 - 8.7 6.1 8.8 0.84 9.3 2.9 2.2 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EGO30806.1 - 9.7 6.2 16.1 0.22 11.5 7.0 2.7 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 Peptidase_C48 PF02902.19 EGO30807.1 - 7.4e-31 107.7 0.7 2.3e-28 99.5 0.7 2.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Croc_4 PF17691.1 EGO30809.1 - 0.042 13.9 0.3 0.073 13.1 0.3 1.4 1 1 0 1 1 1 0 Contingent replication of cDNA 4 ELO PF01151.18 EGO30810.1 - 1.1e-59 202.0 23.3 1.3e-59 201.8 23.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3245 PF11595.8 EGO30812.1 - 0.23 11.9 6.6 0.42 11.1 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) zinc_ribbon_16 PF17034.5 EGO30813.1 - 0.058 13.6 1.0 0.1 12.8 0.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon like family RILP PF11461.8 EGO30815.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF775 PF05603.12 EGO30818.1 - 0.081 12.5 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Helicase_C PF00271.31 EGO30819.1 - 1.8e-14 54.0 0.0 9.5e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGO30819.1 - 0.089 12.0 0.0 0.089 12.0 0.0 2.4 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase Npun_R1517 PF18068.1 EGO30819.1 - 0.12 12.7 0.0 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 Npun R1517 Mito_carr PF00153.27 EGO30820.1 - 1e-61 204.8 0.6 1.4e-21 76.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGO30820.1 - 4.7e-17 62.2 2.5 3.4e-06 27.4 0.0 5.0 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGO30820.1 - 8.5e-16 56.3 5.2 2.5e-05 23.5 0.0 6.2 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EGO30820.1 - 6.4e-15 53.7 4.5 0.00024 20.8 0.1 6.2 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.6 EGO30820.1 - 2e-10 40.3 2.6 0.00055 19.7 0.0 4.8 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGO30820.1 - 5.7e-06 25.6 6.7 0.0077 15.7 0.0 4.3 5 0 0 5 5 5 2 EF hand PP1_inhibitor PF05361.12 EGO30827.1 - 0.091 12.8 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor SUN PF03856.13 EGO30829.1 - 0.022 14.2 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) vMSA PF00695.19 EGO30831.1 - 0.014 14.5 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Retrotrans_gag PF03732.17 EGO30832.1 - 5.8e-07 29.7 0.9 2e-06 28.0 0.1 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Sigma70_r1_2 PF00140.20 EGO30832.1 - 0.01 15.8 0.5 0.017 15.1 0.5 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 WD40 PF00400.32 EGO30833.1 - 4.3e-23 81.2 12.4 5.6e-09 36.5 0.4 3.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO30833.1 - 4.7e-09 36.4 0.2 0.00031 21.0 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO30833.1 - 0.00075 18.6 0.1 0.58 9.1 0.0 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO30833.1 - 0.0034 16.1 0.0 0.28 9.8 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGO30833.1 - 0.032 12.8 0.0 0.044 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ras PF00071.22 EGO30836.1 - 4.2e-57 192.3 0.2 5e-57 192.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO30836.1 - 2.9e-32 111.4 0.0 5e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO30836.1 - 2.4e-13 49.9 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO30836.1 - 3.4e-08 33.5 0.0 5.1e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO30836.1 - 4.6e-07 29.4 0.0 5.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGO30836.1 - 6.7e-06 25.8 0.1 0.00026 20.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO30836.1 - 5.6e-05 23.1 0.2 0.0039 17.1 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 EGO30836.1 - 0.00047 20.0 0.4 0.016 15.0 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGO30836.1 - 0.00051 19.8 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGO30836.1 - 0.00052 19.4 0.3 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Septin cobW PF02492.19 EGO30836.1 - 0.0029 17.2 0.0 0.0099 15.5 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EGO30836.1 - 0.0071 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGO30836.1 - 0.0072 16.7 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO30836.1 - 0.0086 16.4 0.0 0.017 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGO30836.1 - 0.014 15.4 0.0 0.056 13.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGO30836.1 - 0.017 14.8 0.1 0.036 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO30836.1 - 0.025 14.1 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGO30836.1 - 0.042 14.4 0.1 1.1 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGO30836.1 - 0.056 13.3 0.7 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGO30836.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_75 PF07335.11 EGO30836.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NTPase_1 PF03266.15 EGO30836.1 - 0.1 12.5 0.1 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 EGO30836.1 - 0.22 12.0 1.0 0.5 10.9 1.1 1.9 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.11 EGO30837.1 - 4.4e-35 121.7 21.3 5.4e-35 121.4 21.3 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EGO30837.1 - 0.089 13.2 3.1 8.9 6.8 0.1 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EGO30837.1 - 0.28 11.8 13.1 0.13 12.9 4.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA RsbRD_N PF14361.6 EGO30837.1 - 0.43 11.3 5.2 0.33 11.7 0.5 2.4 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Fib_alpha PF08702.10 EGO30837.1 - 0.55 10.4 11.7 2.4 8.3 2.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Turandot PF07240.11 EGO30837.1 - 0.66 10.0 2.4 0.72 9.9 0.2 2.1 2 1 0 2 2 2 0 Stress-inducible humoral factor Turandot Fez1 PF06818.15 EGO30837.1 - 0.68 10.4 14.8 6 7.3 14.9 2.0 1 1 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 EGO30837.1 - 5.6 7.0 18.9 35 4.5 16.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 EGO30837.1 - 6.5 7.3 19.8 0.85 10.1 5.6 2.7 1 1 1 2 2 2 0 Cell division protein ZapB FUSC PF04632.12 EGO30837.1 - 7.6 4.9 6.3 9.1 4.7 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EGO30837.1 - 9.4 5.5 8.7 2.7 7.2 5.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 EGO30837.1 - 9.9 4.9 7.5 12 4.6 7.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2120 PF09893.9 EGO30838.1 - 0.38 10.8 3.9 0.32 11.1 1.7 1.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3854 PF12965.7 EGO30838.1 - 0.66 10.0 3.1 0.37 10.8 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) DivIC PF04977.15 EGO30838.1 - 3.4 7.5 8.9 0.14 11.9 2.7 1.9 2 0 0 2 2 2 0 Septum formation initiator DDE_1 PF03184.19 EGO30839.1 - 3.9e-36 124.3 0.1 5.8e-36 123.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGO30839.1 - 3.6e-05 23.7 0.0 8.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.23 EGO30840.1 - 4.1 7.7 18.6 2.9 8.1 0.1 3.1 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC PF00098.23 EGO30841.1 - 9.2e-07 28.7 5.6 9.2e-07 28.7 5.6 2.8 3 0 0 3 3 3 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO30841.1 - 2.2e-06 27.9 0.3 1.1e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 EGO30841.1 - 0.034 14.1 3.6 0.12 12.3 3.6 1.9 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 EGO30842.1 - 0.0011 18.7 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO30842.1 - 0.0088 16.1 0.0 0.02 14.9 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase_fungal PF17667.1 EGO30847.1 - 2.5e-13 49.6 0.3 3.9e-12 45.7 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase DDE_Tnp_4 PF13359.6 EGO30850.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF2_N PF00176.23 EGO30851.1 - 6.4e-58 196.1 0.9 1e-57 195.4 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 EGO30851.1 - 1.9e-21 76.5 0.1 3.6e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.31 EGO30851.1 - 1.4e-19 70.5 0.0 7.2e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.6 EGO30851.1 - 5.1e-07 29.5 7.6 0.00012 21.7 0.0 2.9 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 EGO30851.1 - 1.8e-05 24.9 0.0 4.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 EGO30851.1 - 7.3e-05 22.6 5.4 0.027 14.4 0.6 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ERCC3_RAD25_C PF16203.5 EGO30851.1 - 0.047 12.9 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zinc_ribbon_5 PF13719.6 EGO30851.1 - 0.099 12.4 1.4 0.46 10.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCCH_6 PF18585.1 EGO30851.1 - 0.38 10.7 1.5 1.8 8.5 1.5 2.2 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 RVT_2 PF07727.14 EGO30853.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tet_JBP PF12851.7 EGO30854.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Peptidase_C48 PF02902.19 EGO30854.1 - 0.13 12.1 0.3 0.24 11.2 0.3 1.4 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain KDZ PF18758.1 EGO30858.1 - 0.00031 20.4 0.1 0.00037 20.2 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase ANAPC15 PF15243.6 EGO30861.1 - 0.22 11.9 0.3 0.22 11.9 0.3 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 15 Prefoldin_2 PF01920.20 EGO30861.1 - 0.37 10.8 9.9 0.7 9.9 2.7 2.6 2 0 0 2 2 2 0 Prefoldin subunit MMR_HSR1 PF01926.23 EGO30862.1 - 4.2e-16 59.0 0.1 6.1e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO30862.1 - 7.5e-07 29.2 0.1 0.0036 17.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGO30862.1 - 7.6e-06 25.5 0.1 4.7e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EGO30862.1 - 0.0064 15.8 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGO30862.1 - 0.019 15.0 0.7 0.071 13.2 0.5 2.0 1 1 0 1 1 1 0 Dynamin family zf-CCHC PF00098.23 EGO30865.1 - 1.1e-07 31.6 3.3 1.9e-07 30.9 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO30865.1 - 0.27 11.0 1.3 0.5 10.1 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C48 PF02902.19 EGO30868.1 - 0.0034 17.3 3.6 0.0065 16.3 3.6 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RPAP3_C PF13877.6 EGO30868.1 - 0.041 14.4 0.1 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 NTF2 PF02136.20 EGO30869.1 - 2.4e-13 50.7 0.0 7.2e-12 45.9 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGO30869.1 - 1.8e-08 34.5 0.0 2.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 zf-CCHC PF00098.23 EGO30870.1 - 4.2e-06 26.6 4.8 8.3e-06 25.7 4.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO30870.1 - 0.12 12.4 5.1 0.22 11.5 5.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Plavaka PF18759.1 EGO30873.1 - 3.5e-08 33.1 0.0 6.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase SepF PF04472.12 EGO30874.1 - 0.038 14.3 0.1 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Cell division protein SepF DUF2321 PF10083.9 EGO30874.1 - 0.18 11.4 0.3 3.7 7.1 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) ROKNT PF08067.11 EGO30874.1 - 0.19 12.0 1.3 0.48 10.8 1.3 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain Enolase_N PF03952.16 EGO30876.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Enolase, N-terminal domain Tox-ODYAM1 PF15642.6 EGO30877.1 - 0.00047 19.2 1.0 0.00055 19.0 1.0 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus DUF5401 PF17380.2 EGO30878.1 - 0.35 8.9 8.3 0.49 8.4 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF148 PF02520.17 EGO30879.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 Dis3l2_C_term PF17877.1 EGO30881.1 - 0.081 13.3 0.1 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal KH_1 PF00013.29 EGO30882.1 - 1.3e-40 137.1 11.0 5.1e-16 58.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGO30882.1 - 3.6e-09 36.4 2.7 0.0032 17.3 0.2 3.5 3 1 0 3 3 3 3 KH domain KH_2 PF07650.17 EGO30882.1 - 4.9e-08 32.7 5.2 0.073 12.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGO30882.1 - 4.9e-05 23.3 4.5 0.041 14.0 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 EGO30882.1 - 0.0049 16.5 0.5 0.36 10.5 0.1 2.5 2 0 0 2 2 2 1 dUTPase MOEP19 PF16005.5 EGO30882.1 - 0.16 12.0 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 KH-like RNA-binding domain TPR_7 PF13176.6 EGO30883.1 - 0.15 12.2 0.1 0.42 10.8 0.1 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat NOA36 PF06524.12 EGO30883.1 - 0.26 10.6 17.7 0.34 10.2 17.7 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EGO30883.1 - 1.9 6.7 9.8 2 6.6 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EGO30883.1 - 2.2 8.3 7.2 2.8 7.9 7.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 EGO30883.1 - 3.3 7.4 12.9 3.8 7.2 12.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EGO30883.1 - 3.3 5.8 13.7 3.6 5.7 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EGO30883.1 - 3.8 7.0 10.8 4.3 6.9 10.8 1.1 1 0 0 1 1 1 0 PPP4R2 zf-CCHC PF00098.23 EGO30890.1 - 1.2e-08 34.7 2.7 2.1e-08 33.9 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGO30890.1 - 0.025 14.5 2.7 0.084 12.9 2.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGO30890.1 - 0.03 14.1 0.4 0.048 13.5 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGO30890.1 - 0.42 10.4 1.7 0.73 9.6 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Exonuc_VII_L PF02601.15 EGO30893.1 - 0.36 10.4 3.9 0.43 10.1 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 EGO30893.1 - 8.7 6.2 9.7 18 5.2 1.2 2.6 1 1 1 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 EGO30896.1 - 1.8e-38 132.4 41.4 3.7e-38 131.4 35.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO30896.1 - 1.3e-11 43.7 7.1 2.3e-11 42.8 2.1 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO30896.1 - 5e-10 38.8 8.3 5e-10 38.8 8.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGO30896.1 - 1.4e-09 37.8 3.0 1.4e-09 37.8 3.0 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ANAPC4_WD40 PF12894.7 EGO30897.1 - 6.9e-09 35.9 0.0 0.025 14.8 0.0 4.5 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO30897.1 - 1.2e-07 32.3 0.7 0.0063 17.3 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 EGO30897.1 - 0.014 15.3 0.0 20 5.0 0.0 4.0 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Plavaka PF18759.1 EGO30898.1 - 4.8e-76 256.1 0.5 7.6e-76 255.4 0.5 1.2 1 0 0 1 1 1 1 Plavaka transposase Peptidase_M41 PF01434.18 EGO30899.1 - 5.7e-62 209.0 0.0 7.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGO30899.1 - 1.1e-25 90.6 0.0 2.1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO30899.1 - 9.6e-14 50.9 0.0 2.7e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain CHAD PF05235.14 EGO30899.1 - 0.0099 15.9 0.1 0.022 14.7 0.0 1.5 2 0 0 2 2 2 1 CHAD domain MFS_1 PF07690.16 EGO30900.1 - 6.1e-27 94.5 27.6 8.4e-26 90.7 29.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EGO30901.1 - 2.8e-27 95.6 36.0 5e-27 94.7 34.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2784 PF10861.8 EGO30901.1 - 1.3 9.1 7.1 5.1 7.2 0.2 3.2 3 0 0 3 3 3 0 Protein of Unknown function (DUF2784) UreD PF01774.17 EGO30903.1 - 6.7e-38 130.7 0.1 8.9e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein NRDE-2 PF08424.10 EGO30904.1 - 2e-65 221.1 4.8 4.1e-65 220.0 4.8 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGO30904.1 - 0.0013 19.4 12.8 0.97 10.4 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat UPF0113_N PF17833.1 EGO30905.1 - 1.2e-29 102.7 0.0 1.8e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGO30905.1 - 2.4e-27 95.0 0.0 4.2e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain HpuA PF16960.5 EGO30905.1 - 0.037 13.2 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter Sec39 PF08314.11 EGO30907.1 - 5.8e-102 342.5 0.0 4.6e-101 339.5 0.0 1.9 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Cgr1 PF03879.14 EGO30908.1 - 3.1e-22 79.0 22.4 4.2e-22 78.6 22.4 1.1 1 0 0 1 1 1 1 Cgr1 family Pep3_Vps18 PF05131.14 EGO30909.1 - 6.3e-51 172.1 0.0 1.3e-50 171.1 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGO30909.1 - 4.9e-08 33.0 0.2 0.002 18.0 0.1 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EGO30909.1 - 7.8e-06 26.3 0.0 2.6e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EGO30909.1 - 5.3e-05 23.1 2.9 6.8e-05 22.8 0.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO30909.1 - 0.00038 20.2 2.0 0.00038 20.2 2.0 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO30909.1 - 0.00056 19.9 2.9 0.00097 19.1 1.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGO30909.1 - 0.0016 18.2 3.5 0.0016 18.2 3.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EGO30909.1 - 0.0023 18.2 4.0 0.0027 18.0 1.0 2.5 2 0 0 2 2 2 1 Ring finger domain Zn_ribbon_17 PF17120.5 EGO30909.1 - 0.008 15.8 0.8 0.029 14.0 0.8 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EGO30909.1 - 0.49 10.3 6.8 0.046 13.6 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EGO30909.1 - 1.2 9.4 5.4 15 6.0 0.6 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EGO30909.1 - 3.1 8.2 4.2 1.5 9.2 0.5 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EGO30909.1 - 9.5 6.4 8.4 1.2 9.2 2.9 2.3 2 0 0 2 2 2 0 Zinc-finger His_Phos_1 PF00300.22 EGO30910.1 - 1e-37 129.7 0.0 1.4e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.27 EGO30911.1 - 7.6e-30 102.7 8.3 1.3e-14 53.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.12 EGO30912.1 - 8e-09 35.6 0.9 1.4e-08 34.8 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TRAPPC-Trs85 PF12739.7 EGO30913.1 - 2.4e-32 112.4 0.1 1.6e-26 93.3 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 EGO30913.1 - 8.1e-05 20.2 0.0 0.00012 19.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Filament_head PF04732.14 EGO30913.1 - 0.15 12.9 11.5 0.65 10.9 11.5 2.1 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region WW PF00397.26 EGO30914.1 - 0.0023 18.0 3.4 0.0041 17.2 3.4 1.4 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 EGO30914.1 - 3.9 7.4 10.4 6.5 6.7 10.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MBD PF01429.19 EGO30915.1 - 0.003 17.2 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain LCCL PF03815.19 EGO30916.1 - 4e-16 58.9 0.1 6.5e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.14 EGO30919.1 - 4.7e-23 82.3 0.0 3.9e-22 79.3 0.0 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) MgtE PF01769.16 EGO30919.1 - 0.036 14.4 1.6 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 Divalent cation transporter adh_short_C2 PF13561.6 EGO30920.1 - 1.1e-39 136.3 0.2 1.9e-39 135.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO30920.1 - 1.2e-36 126.1 0.1 2e-36 125.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO30920.1 - 3e-09 37.0 0.0 5.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EGO30920.1 - 0.0055 17.3 0.1 0.013 16.1 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EGO30920.1 - 0.15 11.4 0.0 0.67 9.3 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) LMWPc PF01451.21 EGO30921.1 - 1.8e-37 128.9 0.0 2e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Aldedh PF00171.22 EGO30922.1 - 9e-127 423.4 0.1 1.1e-126 423.1 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO30922.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) GDI PF00996.18 EGO30924.1 - 1.3e-219 729.1 0.0 1.5e-219 728.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PhnJ PF06007.11 EGO30924.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Rav1p_C PF12234.8 EGO30925.1 - 2.6e-205 683.6 0.0 3.3e-205 683.3 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Kinesin PF00225.23 EGO30926.1 - 5.3e-83 278.7 0.0 9.6e-83 277.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO30926.1 - 3.1e-18 66.2 0.0 2.7e-17 63.1 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Pox_RNA_Pol_19 PF05320.12 EGO30926.1 - 0.078 12.9 2.0 0.16 11.9 2.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Fasciclin PF02469.22 EGO30927.1 - 4.1e-69 230.7 0.0 1e-15 58.1 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 EGO30927.1 - 3.2e-65 216.1 4.4 4.1e-22 77.9 0.2 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein STE3 PF02076.15 EGO30927.1 - 0.12 11.5 0.3 8.9 5.4 0.0 2.7 3 0 0 3 3 3 0 Pheromone A receptor NAT PF04768.13 EGO30928.1 - 2.8e-34 118.2 0.1 3.1e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase F-box PF00646.33 EGO30929.1 - 4.7e-08 32.7 1.2 1.6e-07 31.0 1.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO30929.1 - 0.00073 19.4 1.3 0.0012 18.7 0.4 1.9 2 0 0 2 2 2 1 F-box-like Pkinase_fungal PF17667.1 EGO30930.1 - 2.9e-24 85.6 0.0 4.7e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO30930.1 - 2.5e-11 43.5 0.0 3.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30930.1 - 3.5e-05 23.2 0.0 5.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO30930.1 - 0.0025 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO30930.1 - 0.005 16.8 0.1 0.027 14.4 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO30931.1 - 1.5e-09 37.1 0.0 1.5e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase UQ_con PF00179.26 EGO30932.1 - 5.3e-20 71.5 0.0 9.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4537 PF15057.6 EGO30932.1 - 0.051 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) SKN1 PF03935.15 EGO30933.1 - 2.8e-189 629.7 4.7 3.2e-189 629.5 4.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) p450 PF00067.22 EGO30935.1 - 5e-39 134.3 0.1 1.9e-25 89.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RdRP PF05183.12 EGO30936.1 - 3.8e-126 422.1 0.0 5.5e-126 421.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Prefoldin_2 PF01920.20 EGO30937.1 - 2.1e-22 79.1 12.0 2.8e-22 78.7 12.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit MCU PF04678.13 EGO30937.1 - 0.0084 16.2 3.4 0.014 15.5 3.0 1.5 1 1 0 1 1 1 1 Mitochondrial calcium uniporter MCPsignal PF00015.21 EGO30937.1 - 0.018 14.9 6.2 0.18 11.6 1.8 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1917 PF08939.10 EGO30937.1 - 0.019 14.9 3.2 0.02 14.8 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) Prefoldin_3 PF13758.6 EGO30937.1 - 0.024 14.7 3.6 0.032 14.3 3.3 1.3 1 1 0 1 1 1 0 Prefoldin subunit GTP-bdg_M PF16360.5 EGO30937.1 - 0.024 15.2 2.8 0.077 13.6 2.8 1.9 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region Prefoldin PF02996.17 EGO30937.1 - 0.028 14.3 10.0 0.031 14.2 2.7 2.3 2 1 0 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.12 EGO30937.1 - 0.038 14.5 4.9 1.2 9.6 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 EGO30937.1 - 0.044 14.1 9.3 9.2 6.7 3.8 3.1 2 1 1 3 3 3 0 Tup N-terminal DUF3114 PF11311.8 EGO30937.1 - 0.071 12.6 0.6 0.077 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Spc7 PF08317.11 EGO30937.1 - 0.085 11.7 14.5 0.14 11.0 14.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein End3 PF12761.7 EGO30937.1 - 0.14 12.3 8.3 0.24 11.5 8.3 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.11 EGO30937.1 - 0.14 12.4 13.3 1.5 9.1 1.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FliD_C PF07195.12 EGO30937.1 - 0.16 11.4 5.0 0.19 11.1 3.9 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus GAS PF13851.6 EGO30937.1 - 0.18 11.2 15.4 1.8 7.8 15.4 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 EGO30937.1 - 0.19 11.5 9.8 0.31 10.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Fez1 PF06818.15 EGO30937.1 - 0.21 12.0 12.2 0.32 11.4 4.6 2.1 1 1 1 2 2 2 0 Fez1 DUF1515 PF07439.11 EGO30937.1 - 0.22 11.6 2.0 2.6 8.1 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 EGO30937.1 - 0.22 10.8 8.3 0.3 10.4 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 EGO30937.1 - 0.27 12.0 6.0 1.4 9.7 0.2 2.1 1 1 1 2 2 2 0 Occludin homology domain AAA_23 PF13476.6 EGO30937.1 - 0.27 11.7 11.0 0.4 11.2 11.0 1.2 1 0 0 1 1 1 0 AAA domain YojJ PF10372.9 EGO30937.1 - 0.28 11.3 3.7 0.37 10.9 0.2 2.6 2 2 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus HIP1_clath_bdg PF16515.5 EGO30937.1 - 0.29 11.8 11.8 1.2 9.8 2.7 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WEMBL PF05701.11 EGO30937.1 - 0.4 9.3 13.9 1.3 7.6 2.5 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Rx_N PF18052.1 EGO30937.1 - 0.42 10.9 8.7 0.43 10.9 2.9 2.5 2 1 0 2 2 2 0 Rx N-terminal domain DUF1664 PF07889.12 EGO30937.1 - 0.44 10.6 5.0 1.9 8.6 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EGO30937.1 - 0.46 10.6 14.1 1.1 9.4 1.1 2.1 2 0 0 2 2 2 0 Tropomyosin like YgaB PF14182.6 EGO30937.1 - 0.48 10.8 10.9 0.76 10.2 6.2 2.8 2 2 0 2 2 2 0 YgaB-like protein DUF4164 PF13747.6 EGO30937.1 - 0.56 10.5 11.6 0.46 10.8 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ABC_tran_CTD PF16326.5 EGO30937.1 - 0.6 10.4 14.8 5.3 7.4 6.7 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain FlxA PF14282.6 EGO30937.1 - 0.6 10.1 13.5 0.17 11.9 6.6 2.2 2 0 0 2 2 2 0 FlxA-like protein Atg14 PF10186.9 EGO30937.1 - 0.61 9.1 7.1 0.72 8.9 7.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 EGO30937.1 - 0.68 10.2 9.0 2.1 8.6 3.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 EGO30937.1 - 0.69 10.4 18.9 1.3 9.5 3.2 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EGO30937.1 - 0.86 9.6 13.5 0.98 9.4 0.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.9 EGO30937.1 - 0.95 8.8 12.8 14 4.9 11.6 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 Hrs_helical PF12210.8 EGO30937.1 - 1.2 9.7 8.1 0.23 12.0 0.8 2.4 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate YabA PF06156.13 EGO30937.1 - 1.5 9.5 10.2 1.1 10.0 1.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EGO30937.1 - 1.7 8.7 16.1 3.8 7.6 2.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 EGO30937.1 - 2.9 6.7 14.1 9.1 5.0 14.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF641 PF04859.12 EGO30937.1 - 2.9 8.2 11.5 13 6.1 10.3 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 EGO30937.1 - 4.5 7.5 9.3 55 3.9 0.4 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RF-1 PF00472.20 EGO30937.1 - 6.9 6.6 9.6 10 6.1 3.2 2.1 1 1 1 2 2 2 0 RF-1 domain Fmp27_WPPW PF10359.9 EGO30937.1 - 7.8 5.2 11.1 2.1 7.1 4.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF724 PF05266.14 EGO30937.1 - 8 6.2 11.5 93 2.8 11.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) G_glu_transpept PF01019.21 EGO30938.1 - 2e-142 475.6 0.0 2.3e-142 475.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PP2C PF00481.21 EGO30939.1 - 1.3e-40 139.7 0.0 5.5e-36 124.5 0.0 2.1 1 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGO30939.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C His_Phos_2 PF00328.22 EGO30940.1 - 3.2e-45 155.1 0.0 4e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Git3 PF11710.8 EGO30941.1 - 1.1e-08 35.1 15.7 9.1e-08 32.1 15.7 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EGO30941.1 - 0.00072 19.0 7.4 0.0011 18.4 7.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3325 PF11804.8 EGO30941.1 - 0.087 13.0 0.2 0.087 13.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Pex24p PF06398.11 EGO30941.1 - 0.17 10.9 3.0 0.5 9.3 3.0 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin GPR_Gpa2_C PF11970.8 EGO30941.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.9 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term HemY_N PF07219.13 EGO30941.1 - 4.5 7.5 9.1 0.98 9.7 0.1 3.3 3 0 0 3 3 3 0 HemY protein N-terminus Snf7 PF03357.21 EGO30942.1 - 2.4e-29 102.1 12.8 3.1e-29 101.8 12.8 1.1 1 0 0 1 1 1 1 Snf7 XisI PF08869.11 EGO30942.1 - 0.27 11.6 1.9 0.34 11.3 0.3 1.9 2 0 0 2 2 2 0 XisI protein Pro_isomerase PF00160.21 EGO30943.1 - 1.7e-44 151.9 0.0 2.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EGO30943.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EGO30943.1 - 0.0054 16.5 0.1 0.08 12.8 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EGO30943.1 - 0.038 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain PPR_2 PF13041.6 EGO30945.1 - 1e-50 169.7 0.2 2.4e-09 37.2 0.0 9.1 6 2 5 11 11 11 8 PPR repeat family PPR_3 PF13812.6 EGO30945.1 - 3.6e-35 119.8 0.0 4.4e-07 29.9 0.0 5.9 5 2 1 6 6 6 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO30945.1 - 5e-23 80.5 0.0 0.028 14.1 0.0 10.0 10 0 0 10 10 10 6 PPR repeat PPR PF01535.20 EGO30945.1 - 3.8e-22 76.9 9.7 0.012 15.8 0.0 11.1 12 0 0 12 12 12 5 PPR repeat PPR_long PF17177.4 EGO30945.1 - 6.7e-12 45.2 0.0 0.00013 21.4 0.0 3.7 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EGO30945.1 - 7e-07 29.6 2.7 4.9 8.2 0.1 7.0 6 1 2 8 8 8 2 Tetratricopeptide repeat RPM2 PF08579.11 EGO30945.1 - 0.0022 18.4 0.1 15 6.0 0.0 4.8 5 2 1 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) Trep_dent_lipo PF09710.10 EGO30945.1 - 0.14 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Sugar_tr PF00083.24 EGO30946.1 - 2.6e-102 343.0 13.9 3e-102 342.8 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO30946.1 - 2e-28 99.3 44.7 3.2e-27 95.4 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 EGO30947.1 - 9.9e-22 77.5 0.0 2.3e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO30947.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO30947.1 - 0.0091 16.0 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4203 PF13886.6 EGO30948.1 - 1.3e-46 158.8 35.0 1e-44 152.6 25.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4203) LAG1-DNAbind PF09271.11 EGO30950.1 - 8.8e-27 94.6 0.0 3.6e-16 60.1 0.2 2.4 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 EGO30950.1 - 2e-22 80.0 0.0 5.5e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.21 EGO30951.1 - 1.4e-157 524.0 0.2 2e-157 523.5 0.2 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGO30951.1 - 2.6e-32 111.5 0.0 7.6e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGO30951.1 - 3.5e-05 23.0 0.2 8.7e-05 21.8 0.2 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EGO30951.1 - 0.01 14.9 0.1 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.15 EGO30952.1 - 2.7e-06 27.9 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGO30952.1 - 0.0053 16.2 0.4 0.0082 15.6 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EGO30953.1 - 1.8e-05 25.3 0.0 4.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGO30953.1 - 0.03 13.7 0.3 0.057 12.8 0.3 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein COX6A PF02046.15 EGO30955.1 - 4.5e-30 104.4 0.0 5.2e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Ntox3 PF15536.6 EGO30955.1 - 0.021 14.9 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin 3 2-Hacid_dh_C PF02826.19 EGO30956.1 - 1.4e-54 184.2 0.0 3.6e-54 182.8 0.0 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RPN2_C PF18004.1 EGO30956.1 - 4.4e-40 137.2 2.8 1.9e-38 131.9 2.5 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGO30956.1 - 1.4e-28 97.8 28.3 6.6e-09 35.8 0.0 8.6 8 0 0 8 8 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGO30956.1 - 2e-19 69.7 0.6 1.2e-14 54.5 0.0 5.0 4 1 1 5 5 5 2 HEAT repeats 2-Hacid_dh PF00389.30 EGO30956.1 - 1.6e-09 37.6 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HEAT PF02985.22 EGO30956.1 - 1.9e-05 24.5 0.1 3.7 8.0 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat NAD_binding_2 PF03446.15 EGO30956.1 - 0.00037 20.7 0.1 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HEAT_EZ PF13513.6 EGO30956.1 - 0.0011 19.4 0.2 1.7 9.2 0.0 4.4 2 1 2 4 4 4 2 HEAT-like repeat IlvN PF07991.12 EGO30956.1 - 0.0076 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1702 PF08012.11 EGO30956.1 - 0.029 13.3 0.0 0.67 8.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1702) Adaptin_N PF01602.20 EGO30956.1 - 0.073 11.6 0.0 0.49 8.9 0.0 2.1 2 1 0 2 2 2 0 Adaptin N terminal region COQ7 PF03232.13 EGO30956.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Arm PF00514.23 EGO30957.1 - 7.8e-91 295.7 13.7 2.4e-12 46.4 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EGO30957.1 - 2e-23 82.7 2.2 3.7e-23 81.8 2.2 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 EGO30957.1 - 4e-23 81.5 2.9 3.3e-08 33.9 0.1 6.0 2 1 4 6 6 6 5 HEAT-like repeat Arm_3 PF16186.5 EGO30957.1 - 4.1e-21 74.3 0.4 8.7e-21 73.2 0.4 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 EGO30957.1 - 5.8e-17 61.9 1.4 4e-05 23.9 0.0 5.3 2 1 4 7 7 6 4 HEAT repeats HEAT PF02985.22 EGO30957.1 - 1.2e-15 56.2 0.2 0.00031 20.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 EGO30957.1 - 2.2e-06 27.3 0.1 0.33 10.4 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 EGO30957.1 - 6.1e-06 25.1 0.0 0.00058 18.5 0.0 2.8 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 EGO30957.1 - 6.8e-05 23.0 1.9 0.021 15.1 0.0 4.2 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 EGO30957.1 - 0.00098 19.2 0.1 0.64 10.1 0.0 3.7 3 3 3 6 6 6 2 V-ATPase subunit H HEAT_PBS PF03130.16 EGO30957.1 - 0.0042 17.6 1.6 0.69 10.8 0.1 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 EGO30957.1 - 0.0045 16.4 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Mo25-like LSM PF01423.22 EGO30958.1 - 3.9e-22 77.7 0.1 4.4e-22 77.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO30958.1 - 0.023 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 EGO30958.1 - 0.036 14.2 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Ribosomal_S16 PF00886.19 EGO30959.1 - 3.2e-22 78.4 0.0 4.3e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.19 EGO30960.1 - 7.2e-18 64.6 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 EGO30960.1 - 5.9e-12 45.6 0.1 1.2e-10 41.4 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO30960.1 - 2.6e-10 40.7 0.0 4.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO30960.1 - 3.4e-10 39.9 0.0 8.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EGO30960.1 - 4.1e-09 36.8 0.0 1.6e-06 28.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO30960.1 - 5.1e-08 32.6 0.0 1.7e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat CoA_binding PF02629.19 EGO30961.1 - 2.9e-28 98.4 0.2 7.8e-28 97.0 0.2 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 EGO30961.1 - 1.1e-24 87.0 0.0 1.8e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGO30961.1 - 2e-08 34.1 0.0 6.5e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGO30961.1 - 3.6e-05 24.2 0.2 0.0002 21.9 0.0 2.3 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 EGO30961.1 - 0.085 13.7 0.0 0.29 12.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NTPase_1 PF03266.15 EGO30961.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 NTPase Xpo1 PF08389.12 EGO30962.1 - 1.4e-22 80.3 0.1 4.2e-21 75.6 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EGO30962.1 - 3.7e-06 26.8 0.1 8.2e-05 22.5 0.0 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain DUF3730 PF12530.8 EGO30962.1 - 0.016 14.8 0.0 0.061 12.9 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Tfb2 PF03849.14 EGO30962.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Tfb2 Septin PF00735.18 EGO30963.1 - 9.8e-120 399.1 0.8 1e-119 399.0 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGO30963.1 - 1.3e-07 31.7 0.2 4.8e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGO30963.1 - 0.00017 22.1 1.5 0.046 14.2 0.0 2.7 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EGO30963.1 - 0.00045 20.2 8.0 0.0008 19.4 0.5 3.3 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EGO30963.1 - 0.00047 20.4 0.1 0.0086 16.4 0.0 2.8 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGO30963.1 - 0.0015 18.6 1.4 0.86 9.6 0.0 3.2 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 EGO30963.1 - 0.0038 16.8 5.5 0.049 13.2 0.0 3.6 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGO30963.1 - 0.0054 17.1 0.1 0.061 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 EGO30963.1 - 0.012 15.0 0.2 0.042 13.2 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Ras PF00071.22 EGO30963.1 - 0.014 15.0 0.0 0.13 11.9 0.0 2.5 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.6 EGO30963.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGO30963.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EGO30963.1 - 0.13 12.5 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGO30963.1 - 0.64 9.8 5.6 3 7.6 0.0 3.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Dzip-like_N PF13815.6 EGO30963.1 - 0.67 9.9 5.9 1.5 8.8 5.9 1.6 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Strep_SA_rep PF06696.11 EGO30963.1 - 0.93 9.6 7.5 0.31 11.1 3.9 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF3987 PF13148.6 EGO30963.1 - 7 5.6 8.9 27 3.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CN_hydrolase PF00795.22 EGO30965.1 - 1.5e-55 188.4 0.0 1.8e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.9 EGO30966.1 - 1.5e-26 93.3 0.0 2.2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.13 EGO30967.1 - 6.8e-55 185.2 0.0 7.7e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.6 EGO30967.1 - 0.017 15.1 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c PHD PF00628.29 EGO30967.1 - 0.026 14.4 1.1 0.067 13.1 0.5 1.9 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_SprT PF17283.2 EGO30967.1 - 0.045 13.7 1.4 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_12 PF11331.8 EGO30967.1 - 0.12 12.2 0.3 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain Rubredoxin_2 PF18073.1 EGO30967.1 - 0.17 11.7 4.2 0.79 9.5 0.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain IQ PF00612.27 EGO30969.1 - 0.055 13.3 2.5 0.12 12.3 2.5 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF1248 PF06852.12 EGO30969.1 - 0.075 12.5 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Pkinase PF00069.25 EGO30970.1 - 7.1e-67 225.5 0.0 9.3e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO30970.1 - 4e-46 157.4 0.0 6e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO30970.1 - 2.1e-08 33.9 0.0 5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGO30970.1 - 0.00025 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGO30970.1 - 0.0027 16.5 0.1 0.0056 15.5 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGO30970.1 - 0.044 12.7 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EGO30970.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGO30970.1 - 0.25 10.9 0.4 12 5.4 0.4 2.3 2 0 0 2 2 2 0 RIO1 family CAAX_1 PF15895.5 EGO30970.1 - 2 8.3 7.5 17 5.2 4.6 2.4 2 0 0 2 2 2 0 CAAX box cerebral protein 1 CLTH PF10607.9 EGO30971.1 - 7.8e-33 113.4 0.1 1.1e-32 113.0 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGO30971.1 - 2.9e-11 42.9 0.2 6e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 LisH CSTF1_dimer PF16699.5 EGO30971.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain ATP_bind_2 PF03668.15 EGO30971.1 - 0.25 10.6 1.1 3.5 6.9 0.1 2.0 1 1 1 2 2 2 0 P-loop ATPase protein family BATS PF06968.13 EGO30972.1 - 1e-22 80.0 0.1 4e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGO30972.1 - 2.3e-14 54.1 0.0 3.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily HABP4_PAI-RBP1 PF04774.15 EGO30973.1 - 2.4e-12 47.7 6.7 2.4e-12 47.7 6.7 2.2 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 EGO30973.1 - 0.0003 21.6 3.5 0.0003 21.6 3.5 4.9 5 2 0 5 5 5 1 Stm1 zf-CCHC PF00098.23 EGO30975.1 - 1.3e-07 31.3 1.2 2e-07 30.8 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO30975.1 - 0.0083 16.0 0.5 0.013 15.3 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf_C2H2_13 PF18508.1 EGO30975.1 - 0.015 14.9 0.3 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger domain RRM_1 PF00076.22 EGO30976.1 - 2e-54 181.3 0.0 9.7e-19 67.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO30976.1 - 1.2e-08 34.6 0.0 0.0001 21.9 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO30976.1 - 7.4e-07 28.9 0.0 0.00027 20.7 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGO30976.1 - 0.0034 17.4 0.1 1.9 8.6 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EGO30976.1 - 0.0054 16.8 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EGO30976.1 - 0.018 15.2 0.0 0.48 10.6 0.0 3.0 3 1 0 3 3 3 0 RNA recognition motif PHM7_cyt PF14703.6 EGO30976.1 - 0.17 12.1 0.0 27 4.9 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_S27e PF01667.17 EGO30977.1 - 1.2e-29 101.7 3.4 1.5e-29 101.5 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 EGO30977.1 - 0.044 14.2 1.5 0.26 11.7 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) TF_Zn_Ribbon PF08271.12 EGO30977.1 - 0.14 11.7 1.1 0.21 11.1 1.1 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Pribosyltran_N PF13793.6 EGO30978.1 - 4.1e-45 152.5 2.1 5.5e-44 148.8 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGO30978.1 - 3e-38 131.7 2.7 1.5e-32 113.1 1.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGO30978.1 - 5.9e-17 61.6 2.0 1.2e-15 57.4 0.8 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO30978.1 - 0.0025 17.3 0.3 0.0046 16.4 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SDH_sah PF01972.16 EGO30978.1 - 0.039 12.9 0.1 0.06 12.3 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF848 PF05852.11 EGO30978.1 - 0.048 13.8 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DnaJ_C PF01556.18 EGO30979.1 - 1.3e-38 132.4 0.0 1.7e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO30979.1 - 4.4e-24 84.4 2.3 8.3e-24 83.5 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO30979.1 - 9.8e-08 32.3 20.5 1.3e-07 31.9 19.1 2.0 2 0 0 2 2 2 1 DnaJ central domain MFS_1 PF07690.16 EGO30980.1 - 2.9e-39 135.0 43.7 8e-39 133.5 43.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO30980.1 - 3.4e-12 46.0 8.2 3.4e-12 46.0 8.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter HEAT PF02985.22 EGO30982.1 - 1.9e-41 136.5 13.2 0.0029 17.7 0.0 13.5 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 EGO30982.1 - 4.9e-32 110.2 11.8 3.5e-11 43.4 0.0 7.2 2 2 5 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 EGO30982.1 - 3.9e-12 46.6 0.8 0.025 15.1 0.0 7.1 3 3 5 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGO30982.1 - 8.3e-10 39.0 10.0 1.5 9.4 0.0 8.7 10 2 2 12 12 12 3 HEAT-like repeat Cnd1 PF12717.7 EGO30982.1 - 4.5e-08 33.3 4.9 0.14 12.2 0.1 5.1 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGO30982.1 - 1.1e-06 27.5 4.7 0.0082 14.7 0.1 3.9 2 2 1 3 3 3 2 Adaptin N terminal region Arm PF00514.23 EGO30982.1 - 4.8e-05 23.3 1.3 1.4 9.1 0.1 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 EGO30982.1 - 0.0003 21.0 0.3 0.91 9.9 0.0 4.8 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain Ecm29 PF13001.7 EGO30982.1 - 0.019 13.7 3.6 2 7.0 0.1 3.6 3 1 0 3 3 3 0 Proteasome stabiliser HEAT_PBS PF03130.16 EGO30982.1 - 0.056 14.1 9.3 0.68 10.8 0.2 6.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat BRCA-2_OB1 PF09103.10 EGO30985.1 - 8.5e-37 125.8 0.0 1.9e-36 124.7 0.0 1.6 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EGO30985.1 - 1.7e-05 24.6 0.4 3.5e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 BRCA2, helical Taxilin PF09728.9 EGO30986.1 - 1.2e-17 64.0 33.6 2.7e-10 39.9 18.9 2.4 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 EGO30986.1 - 2.6e-07 30.4 1.6 0.0064 16.3 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF2935 PF11155.8 EGO30986.1 - 0.058 13.7 2.3 0.15 12.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) PriA_C PF18074.1 EGO30986.1 - 0.084 13.7 3.6 0.11 13.3 0.1 3.0 2 1 1 3 3 3 0 Primosomal protein N C-terminal domain Ntox28 PF15605.6 EGO30986.1 - 0.35 11.1 10.7 0.6 10.4 0.8 3.3 2 1 0 2 2 2 0 Bacterial toxin 28 DUF1664 PF07889.12 EGO30986.1 - 2.4 8.2 8.4 2.7 8.1 6.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EGO30986.1 - 5.4 4.8 7.7 9.8 4.0 7.7 1.3 1 0 0 1 1 1 0 Prominin UDPGP PF01704.18 EGO30987.1 - 2.4e-45 154.9 0.0 3e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGO30987.1 - 0.0075 16.6 0.1 0.048 14.0 0.1 2.3 2 1 0 2 2 2 1 MobA-like NTP transferase domain Cellulase PF00150.18 EGO30988.1 - 1e-13 51.4 0.1 1e-13 51.4 0.1 2.0 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 EGO30989.1 - 8.5e-14 51.6 0.5 1.6e-13 50.8 0.5 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M16 PF00675.20 EGO30990.1 - 4.4e-37 127.3 0.0 9.8e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO30990.1 - 2e-33 115.9 0.0 4.5e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain EF_TS PF00889.19 EGO30991.1 - 5.5e-16 58.8 0.0 1.5e-14 54.1 0.0 2.3 1 1 1 2 2 2 2 Elongation factor TS UBA_4 PF14555.6 EGO30991.1 - 0.0026 17.6 0.1 0.0063 16.3 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain Gar1 PF04410.14 EGO30992.1 - 9.1e-33 113.2 0.1 1.7e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribonuclease_T2 PF00445.18 EGO30993.1 - 6.3e-39 134.1 0.1 9.8e-39 133.5 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.6 EGO30994.1 - 1.5e-20 72.8 0.0 2.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain Tic22 PF04278.12 EGO30994.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Tic22-like family PEHE PF15275.6 EGO30995.1 - 6.7e-06 26.8 0.6 6.7e-06 26.8 0.6 2.3 2 1 0 2 2 2 1 PEHE domain SAS4 PF15460.6 EGO30995.1 - 8.2e-05 22.6 3.4 0.00018 21.6 3.4 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHHC PF01529.20 EGO30996.1 - 4.7e-38 130.3 7.8 4.7e-38 130.3 7.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4052 PF13261.6 EGO30996.1 - 0.065 13.1 0.4 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4052) Bromodomain PF00439.25 EGO30997.1 - 2.4e-20 72.4 0.2 3.3e-20 71.9 0.2 1.2 1 0 0 1 1 1 1 Bromodomain Cyt-b5 PF00173.28 EGO30998.1 - 5.8e-06 26.4 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EGO30998.1 - 7.4e-05 22.7 16.5 0.00067 19.6 10.1 3.1 2 1 1 3 3 3 2 Fatty acid desaturase CutC PF03932.14 EGO30999.1 - 9.4e-55 185.2 0.0 1.2e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 CutC family F-box-like PF12937.7 EGO31000.1 - 7e-08 32.2 2.0 1.8e-07 30.9 2.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO31000.1 - 9.2e-08 31.8 1.4 2.2e-07 30.6 1.4 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO31000.1 - 0.036 14.0 0.3 0.098 12.5 0.3 1.7 1 0 0 1 1 1 0 F-box FtsX PF02687.21 EGO31001.1 - 0.21 12.1 5.3 0.65 10.5 0.1 2.5 2 0 0 2 2 2 0 FtsX-like permease family Glyco_transf_22 PF03901.17 EGO31002.1 - 6.2e-83 279.3 18.9 1.4e-82 278.2 18.9 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family RPAP1_C PF08620.10 EGO31003.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, C-terminal CENP-T_C PF15511.6 EGO31004.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGO31004.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGO31004.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO31004.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO31004.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGO31004.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 EGO31005.1 - 1.9e-25 88.8 0.0 2.4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGO31005.1 - 2.6e-07 31.1 0.1 1.7e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGO31005.1 - 2.2e-05 24.7 0.0 0.00088 19.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EGO31005.1 - 0.00026 20.9 0.1 0.00056 19.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGO31005.1 - 0.0004 20.2 0.0 0.00055 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGO31005.1 - 0.00056 19.4 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGO31005.1 - 0.0018 18.4 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EGO31005.1 - 0.0022 17.7 0.1 0.011 15.4 0.1 2.0 2 1 0 2 2 2 1 Redoxin DUF953 PF06110.11 EGO31005.1 - 0.12 12.0 0.0 0.53 9.9 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) PBP1_TM PF14812.6 EGO31006.1 - 1.4 9.3 5.3 4 7.9 5.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pyrophosphatase PF00719.19 EGO31007.1 - 1.1e-59 200.8 0.3 1.6e-59 200.3 0.3 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase GCP_C_terminal PF04130.13 EGO31008.1 - 1.5e-28 100.2 0.0 4e-28 98.8 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGO31008.1 - 1.2e-21 77.7 0.2 9.7e-20 71.4 0.2 2.6 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal RabGAP-TBC PF00566.18 EGO31009.1 - 6.6e-33 114.2 0.0 1.2e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EGO31009.1 - 0.0014 16.9 0.5 0.0014 16.9 0.5 1.8 1 1 1 2 2 2 1 SBE2, cell-wall formation Nop52 PF05997.12 EGO31010.1 - 2.5e-36 125.5 0.3 2.7e-36 125.4 0.3 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 NACHT PF05729.12 EGO31013.1 - 0.00013 22.0 0.1 0.00027 20.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Neuralized PF07177.12 EGO31013.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Neuralized UQ_con PF00179.26 EGO31014.1 - 5.2e-40 136.3 0.1 6.6e-40 136.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGO31014.1 - 0.0091 16.3 0.1 0.012 15.9 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EGO31014.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 EGO31014.1 - 0.056 13.1 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B 2OG-FeII_Oxy PF03171.20 EGO31015.1 - 1.2e-05 25.7 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PPR_2 PF13041.6 EGO31016.1 - 4.4e-35 119.6 0.1 3.9e-07 30.1 0.0 6.9 4 1 2 6 6 6 6 PPR repeat family PPR_3 PF13812.6 EGO31016.1 - 2.1e-23 82.2 0.6 3e-07 30.4 0.0 5.7 4 1 1 5 5 5 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO31016.1 - 3.2e-21 74.7 0.0 1.4e-06 27.9 0.0 6.8 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 EGO31016.1 - 2.5e-18 64.9 2.7 4.2e-05 23.5 0.0 7.2 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 EGO31016.1 - 1.4e-12 47.4 1.4 1.3e-05 24.7 0.1 4.1 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EGO31016.1 - 6.9e-06 26.5 1.2 12 7.0 0.0 5.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO31016.1 - 0.00074 20.0 0.1 4.3 7.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ELYS PF13934.6 EGO31016.1 - 0.0051 16.8 0.5 0.25 11.3 0.0 3.5 3 2 0 3 3 3 1 Nuclear pore complex assembly ECSIT PF06239.11 EGO31016.1 - 0.019 14.1 0.1 4.7 6.3 0.0 2.8 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.11 EGO31016.1 - 0.05 14.0 0.8 34 4.9 0.1 4.0 4 1 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_4 PF07721.14 EGO31016.1 - 0.078 13.6 0.6 4.8 8.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Chorismate_bind PF00425.18 EGO31017.1 - 3.5e-65 220.1 0.0 6.6e-65 219.2 0.0 1.5 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGO31017.1 - 3.8e-34 118.1 0.0 5.4e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EGO31017.1 - 1e-16 61.4 0.0 3.5e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EGO31017.1 - 8.1e-06 25.7 2.2 3.2e-05 23.8 2.2 1.9 1 1 0 1 1 1 1 Peptidase C26 AAA-ATPase_like PF09820.9 EGO31017.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase HEAT PF02985.22 EGO31018.1 - 2.2e-05 24.3 3.7 0.086 13.1 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EGO31018.1 - 1 9.9 3.2 64 4.2 0.1 4.2 3 0 0 3 3 3 0 HEAT-like repeat RNase_P_pop3 PF08228.11 EGO31020.1 - 1.8e-14 54.1 0.0 1.7e-10 41.2 0.0 2.7 2 1 0 2 2 2 2 RNase P subunit Pop3 Amidase PF01425.21 EGO31021.1 - 9.5e-101 338.0 0.0 1.2e-100 337.7 0.0 1.1 1 0 0 1 1 1 1 Amidase TPT PF03151.16 EGO31024.1 - 2.2e-09 37.1 15.3 3.8e-09 36.3 15.3 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO31024.1 - 5.6e-09 36.3 31.8 0.00014 22.1 12.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family O-FucT PF10250.9 EGO31025.1 - 2.1e-12 47.4 0.0 7e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ApbA_C PF08546.11 EGO31026.1 - 9.3e-31 106.6 0.1 2e-30 105.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGO31026.1 - 4.9e-23 81.4 0.1 2.1e-22 79.4 0.1 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EGO31026.1 - 0.05 13.9 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.21 EGO31027.1 - 1.8e-38 132.4 0.0 2.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 EGO31029.1 - 1.2e-06 28.3 2.7 2.9e-06 27.1 2.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO31029.1 - 0.15 11.9 2.8 2 8.4 2.8 2.5 1 1 0 1 1 1 0 F-box domain Homeodomain PF00046.29 EGO31030.1 - 4.5e-14 52.0 2.4 2.4e-13 49.7 1.1 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EGO31030.1 - 0.0016 18.3 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain PI3K_1B_p101 PF10486.9 EGO31030.1 - 0.59 7.9 3.7 0.79 7.4 3.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Homeodomain PF00046.29 EGO31031.1 - 2.2e-15 56.2 2.6 4.1e-15 55.4 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGO31031.1 - 0.039 13.8 0.2 0.096 12.6 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain AC_N PF16214.5 EGO31031.1 - 0.16 11.0 1.1 0.24 10.5 1.1 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region WD40 PF00400.32 EGO31032.1 - 6.6e-15 55.2 8.4 0.0014 19.4 0.0 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO31032.1 - 0.00056 20.2 0.3 9.1 6.7 0.0 4.7 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_25 PF13649.6 EGO31033.1 - 3.1e-13 50.2 0.0 7.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO31033.1 - 6.6e-11 42.7 0.0 1.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO31033.1 - 9.8e-10 38.5 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO31033.1 - 1.8e-06 27.8 0.0 3.9e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO31033.1 - 4.1e-06 26.3 0.0 1.6e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGO31033.1 - 5.2e-06 25.9 0.0 8.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EGO31033.1 - 0.00021 22.0 0.0 0.0004 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGO31033.1 - 0.00056 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EGO31033.1 - 0.0008 19.6 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 EGO31033.1 - 0.007 15.0 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EGO31033.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Plavaka PF18759.1 EGO31034.1 - 1.1e-73 248.3 0.0 1.5e-62 211.8 0.1 2.3 1 1 1 2 2 2 2 Plavaka transposase DDE_Tnp_4 PF13359.6 EGO31036.1 - 5.7e-14 52.1 0.0 1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2293 PF10056.9 EGO31036.1 - 0.074 13.3 0.8 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) DTHCT PF08070.11 EGO31036.1 - 0.16 12.7 1.9 0.27 12.0 1.9 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Pyr_redox_2 PF07992.14 EGO31037.1 - 1.4e-32 113.1 0.1 1.8e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO31037.1 - 2.2e-16 60.2 0.5 2.2e-12 47.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO31037.1 - 8.8e-10 38.3 0.0 3e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO31037.1 - 6.6e-07 29.2 4.8 0.0051 16.4 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO31037.1 - 2.7e-05 24.2 2.3 0.019 14.9 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGO31037.1 - 5.9e-05 22.3 0.3 0.093 11.8 0.1 3.2 3 1 0 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.6 EGO31037.1 - 9.9e-05 21.6 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EGO31037.1 - 0.003 17.6 0.3 0.75 9.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EGO31037.1 - 0.0087 16.3 1.4 1.8 8.8 0.2 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EGO31037.1 - 0.017 15.5 0.1 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EGO31037.1 - 0.024 14.9 1.5 9.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGO31037.1 - 0.049 14.2 1.9 4.9 7.8 0.1 3.6 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 EGO31037.1 - 0.087 13.1 1.1 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO31037.1 - 0.11 11.8 0.7 3.4 6.8 0.1 2.6 3 0 0 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 EGO31037.1 - 0.24 10.2 1.7 0.67 8.7 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 EGO31037.1 - 0.36 9.9 6.8 14 4.6 0.2 4.0 4 1 1 5 5 5 0 Glucose inhibited division protein A MMR_HSR1 PF01926.23 EGO31038.1 - 4.6e-11 42.8 0.0 1.9e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO31038.1 - 0.00031 20.3 0.0 0.007 15.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO31038.1 - 0.0084 16.0 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arrestin_C PF02752.22 EGO31040.1 - 4.8e-11 43.3 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain PRIMA1 PF16101.5 EGO31041.1 - 0.086 12.9 2.3 0.29 11.2 2.3 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF5350 PF17299.2 EGO31041.1 - 0.16 12.4 0.0 0.44 11.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5350) DUF1741 PF08427.10 EGO31042.1 - 6.2e-27 94.8 2.7 9.7e-27 94.1 0.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) GDC-P PF02347.16 EGO31043.1 - 3.4e-183 609.4 0.0 1.4e-174 581.0 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGO31043.1 - 0.0024 16.9 0.1 0.022 13.7 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGO31043.1 - 0.0043 16.4 0.1 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase PPR_2 PF13041.6 EGO31044.1 - 1e-21 76.8 0.4 0.0098 16.1 0.1 10.2 8 3 3 11 11 11 6 PPR repeat family PPR PF01535.20 EGO31044.1 - 1.1e-10 41.0 7.0 0.76 10.2 0.2 7.7 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 EGO31044.1 - 9.3e-09 35.2 0.2 1.9 8.6 0.0 7.8 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGO31044.1 - 2.8e-07 30.1 1.0 0.051 12.9 0.4 4.3 4 1 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGO31044.1 - 0.00013 21.6 0.6 4.2 7.1 0.1 5.8 8 0 0 8 8 8 2 PPR repeat SecE PF00584.20 EGO31046.1 - 3.7e-14 52.4 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Vps51 PF08700.11 EGO31048.1 - 3.7e-12 46.2 0.8 1.7e-11 44.1 0.8 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Flg_bbr_C PF06429.13 EGO31048.1 - 0.00054 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal DRY_EERY PF09750.9 EGO31048.1 - 0.63 10.3 4.3 0.27 11.5 1.1 1.9 2 0 0 2 2 2 0 Alternative splicing regulator DUF1751 PF08551.10 EGO31049.1 - 2.3e-22 79.4 5.4 4.4e-22 78.5 5.4 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGO31049.1 - 0.0023 18.0 6.6 0.0051 16.8 6.7 1.5 1 1 0 1 1 1 1 Rhomboid family DUF1754 PF08555.10 EGO31050.1 - 9.3e-13 48.8 4.0 9.3e-13 48.8 4.0 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Herpes_LP PF03363.13 EGO31050.1 - 0.0029 17.4 0.1 0.0035 17.2 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus leader protein DUF4191 PF13829.6 EGO31050.1 - 0.033 13.5 0.6 0.043 13.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) WSD PF15613.6 EGO31051.1 - 0.0026 18.2 0.0 0.0048 17.4 0.0 1.6 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif TMF_DNA_bd PF12329.8 EGO31051.1 - 0.013 15.5 2.6 0.027 14.4 2.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Osmo_CC PF08946.10 EGO31051.1 - 0.069 13.4 0.7 0.17 12.2 0.7 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF1192 PF06698.11 EGO31051.1 - 0.16 12.0 5.1 0.064 13.3 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_M3 PF01432.20 EGO31053.1 - 1e-129 433.8 0.0 1.3e-129 433.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 F-protein PF00469.20 EGO31054.1 - 1.2 8.7 3.1 0.44 10.1 0.1 1.8 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Mating_C PF12737.7 EGO31057.1 - 2.6e-22 79.7 24.6 3.4e-21 76.0 24.6 2.8 1 1 0 1 1 1 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.11 EGO31057.1 - 3.9e-12 45.9 0.1 1e-11 44.5 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.7 EGO31057.1 - 1.6e-07 31.3 1.9 3.7e-07 30.1 1.9 1.7 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeodomain PF00046.29 EGO31057.1 - 0.00045 20.0 0.0 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain DASH_Dad2 PF08654.10 EGO31057.1 - 0.44 11.0 7.7 32 5.0 0.3 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad2 Homeodomain PF00046.29 EGO31058.1 - 7.6e-13 48.1 1.8 1.8e-12 46.9 1.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGO31058.1 - 5.8e-08 32.5 1.8 7.6e-08 32.1 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 EGO31058.1 - 0.00053 19.4 0.0 0.0022 17.4 0.0 2.0 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Ribosomal_L26 PF16906.5 EGO31058.1 - 0.19 12.2 2.3 0.54 10.8 2.3 1.8 1 1 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal DUF883 PF05957.13 EGO31059.1 - 0.0033 18.0 2.3 0.024 15.2 0.1 2.4 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 EGO31059.1 - 0.0042 17.0 1.2 0.0091 15.9 0.1 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 EGO31059.1 - 0.0061 16.7 3.1 0.021 14.9 0.3 2.1 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) Endotoxin_C2 PF18449.1 EGO31059.1 - 0.066 13.6 0.5 0.24 11.8 0.5 2.0 1 1 0 1 1 1 0 Delta endotoxin Glyco_transf_8 PF01501.20 EGO31060.1 - 7e-22 78.2 0.0 3.2e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 STE3 PF02076.15 EGO31061.1 - 2.3e-34 118.9 7.2 6.1e-33 114.3 7.2 2.0 1 1 0 1 1 1 1 Pheromone A receptor Thr_synth_N PF14821.6 EGO31061.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonine synthase N terminus SAICAR_synt PF01259.18 EGO31062.1 - 9.6e-97 323.5 0.0 1.2e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Chitin_synth_1 PF01644.17 EGO31066.1 - 1.5e-71 239.6 0.4 2.3e-71 239.0 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO31066.1 - 1.5e-27 95.4 0.0 4.6e-27 93.8 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO31066.1 - 2.3e-24 86.0 0.2 3.9e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO31066.1 - 3.1e-06 27.2 7.3 6.2e-05 23.0 7.3 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO31066.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Homeodomain PF00046.29 EGO31067.1 - 3.3e-48 161.3 11.5 4.3e-16 58.5 0.1 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 EGO31067.1 - 1.3e-15 57.0 1.0 1.4e-05 24.9 0.1 3.8 3 0 0 3 3 3 3 Homeobox KN domain HOCHOB PF17943.1 EGO31067.1 - 5.1e-09 36.9 0.0 0.45 11.2 0.0 3.3 3 0 0 3 3 3 3 Homeobox-cysteine loop-homeobox YdaS_antitoxin PF15943.5 EGO31067.1 - 2.6e-05 24.0 0.0 0.33 10.9 0.0 3.6 4 0 0 4 4 4 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 EGO31067.1 - 0.00025 21.0 0.5 0.47 10.5 0.0 3.8 4 0 0 4 4 4 2 Helix-turn-helix Homez PF11569.8 EGO31067.1 - 0.0088 15.5 0.5 4.5 6.8 0.0 3.2 3 0 0 3 3 3 2 Homeodomain leucine-zipper encoding, Homez Phage_CI_repr PF07022.13 EGO31067.1 - 0.14 12.3 0.0 13 6.0 0.1 2.7 3 0 0 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain Fumble PF03630.14 EGO31068.1 - 3.8e-130 433.9 0.0 5e-130 433.5 0.0 1.1 1 0 0 1 1 1 1 Fumble Adaptin_N PF01602.20 EGO31069.1 - 3.7e-116 388.8 0.0 5e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGO31069.1 - 2.6e-57 193.2 3.3 7.1e-57 191.8 3.3 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGO31069.1 - 1.9e-34 118.3 0.0 4.3e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGO31069.1 - 4.2e-17 62.3 1.6 3.4e-09 37.0 0.0 6.0 2 2 4 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EGO31069.1 - 1.4e-05 25.2 7.8 0.079 13.0 0.1 5.1 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EGO31069.1 - 0.017 15.2 0.3 53 4.0 0.0 4.4 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGO31069.1 - 0.059 13.7 7.1 18 5.9 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat HEAT_PBS PF03130.16 EGO31069.1 - 0.068 13.9 0.9 21 6.1 0.1 5.1 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat DUF3385 PF11865.8 EGO31069.1 - 0.1 12.5 0.1 2.8 7.8 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 EGO31069.1 - 1.9 9.1 6.3 36 5.0 1.4 4.1 3 2 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 EGO31070.1 - 1.5e-25 90.1 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO31070.1 - 4.4e-13 49.1 0.0 6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO31070.1 - 2e-09 36.7 0.0 3.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO31070.1 - 0.0013 18.8 0.0 0.0077 16.2 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGO31070.1 - 0.046 12.7 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1912 PF08930.10 EGO31070.1 - 0.25 11.5 2.5 0.72 10.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) cNMP_binding PF00027.29 EGO31071.1 - 1e-29 102.4 0.1 3.5e-16 59.1 0.0 5.3 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EGO31071.1 - 4.2e-18 66.3 4.2 4.2e-12 46.7 2.4 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase Sec1 PF00995.23 EGO31072.1 - 6.4e-116 388.9 0.0 7.3e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3412 PF11892.8 EGO31072.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) YABBY PF04690.13 EGO31073.1 - 1e-08 35.9 1.8 1.1e-08 35.8 1.8 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.10 EGO31073.1 - 0.00077 20.0 1.1 0.00077 20.0 1.1 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 EGO31073.1 - 0.0068 16.8 2.6 0.0068 16.8 2.6 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box Ccdc124 PF06244.12 EGO31073.1 - 0.13 12.8 6.4 0.22 12.1 6.4 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 F-box-like PF12937.7 EGO31074.1 - 5.8e-06 26.1 0.0 3.5e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGO31074.1 - 0.024 14.7 5.0 0.14 12.2 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat F-box PF00646.33 EGO31074.1 - 0.07 13.0 1.0 4.1 7.4 0.0 3.7 3 0 0 3 3 3 0 F-box domain Sas10_Utp3 PF04000.15 EGO31076.1 - 2.8e-17 63.1 0.1 6.4e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SF3b10 PF07189.11 EGO31077.1 - 6.3e-35 119.1 0.0 7.7e-35 118.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_25 PF13649.6 EGO31078.1 - 1.4e-11 45.0 0.0 2.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO31078.1 - 2.7e-09 37.5 0.0 5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO31078.1 - 3.2e-06 27.1 0.0 5.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO31078.1 - 1.8e-05 25.4 0.0 8.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO31078.1 - 0.00017 21.4 0.0 0.00056 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO31078.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGO31078.1 - 0.002 17.5 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGO31078.1 - 0.11 12.0 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain HTH_8 PF02954.19 EGO31078.1 - 0.17 11.7 1.4 44 4.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family WLM PF08325.10 EGO31079.1 - 3.4e-55 187.1 0.0 5e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EGO31079.1 - 4.6e-06 25.8 1.5 4.6e-06 25.8 1.5 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 EGO31079.1 - 0.00033 20.8 0.8 0.00069 19.7 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SVIP PF15811.5 EGO31079.1 - 0.0029 18.0 4.2 0.23 11.9 0.0 2.5 2 0 0 2 2 2 2 Small VCP/p97-interacting protein DZR PF12773.7 EGO31079.1 - 0.043 13.8 8.7 0.095 12.7 8.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 EGO31079.1 - 1.4 9.1 10.5 12 6.0 0.1 3.5 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger C1_2 PF03107.16 EGO31079.1 - 1.7 9.1 7.9 11 6.4 1.2 2.4 1 1 1 2 2 2 0 C1 domain Methyltransf_16 PF10294.9 EGO31080.1 - 0.00012 21.9 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGO31080.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGO31080.1 - 0.19 11.3 0.1 0.41 10.2 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Bot1p PF12298.8 EGO31081.1 - 1.8e-27 96.6 0.1 3.4e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 EGO31081.1 - 0.072 13.2 1.9 0.64 10.2 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial ribosomal protein subunit L20 MFS_1 PF07690.16 EGO31082.1 - 3.4e-20 72.3 23.5 5.1e-20 71.7 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.19 EGO31082.1 - 0.085 13.3 0.4 0.19 12.2 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box DUF1772 PF08592.11 EGO31082.1 - 0.3 11.4 8.3 1.3 9.3 0.1 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) Cpn60_TCP1 PF00118.24 EGO31083.1 - 1.2e-152 509.0 0.2 1.4e-152 508.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.23 EGO31084.1 - 1.8e-68 230.8 0.0 2.6e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EGO31084.1 - 2.9e-16 59.2 0.0 1.1e-15 57.4 0.0 1.9 2 0 0 2 2 1 1 HIRAN domain Helicase_C PF00271.31 EGO31084.1 - 3.5e-15 56.3 0.0 7.8e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO31084.1 - 5.1e-09 36.4 0.0 2.9e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EGO31084.1 - 1.5e-07 31.2 14.1 3.3e-06 26.8 13.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO31084.1 - 1.6e-06 27.9 14.7 3.1e-06 26.9 14.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO31084.1 - 3e-05 24.3 13.9 6.4e-05 23.2 13.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO31084.1 - 3.1e-05 23.7 11.0 5.5e-05 22.9 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO31084.1 - 0.00092 19.2 14.0 0.0024 17.9 13.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO31084.1 - 0.0014 18.7 14.2 0.003 17.7 14.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 EGO31084.1 - 0.013 15.3 8.3 0.024 14.4 8.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.6 EGO31084.1 - 0.11 12.5 12.3 0.19 11.7 12.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 EGO31084.1 - 0.14 12.0 6.8 0.38 10.6 6.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ICL PF00463.21 EGO31085.1 - 9.8e-193 641.4 0.0 1.1e-192 641.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGO31085.1 - 1.2e-09 38.0 0.1 3.3e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase CsoSCA PF08936.10 EGO31087.1 - 0.025 13.3 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase HLH PF00010.26 EGO31089.1 - 6.9e-11 41.9 3.6 7.1e-11 41.9 1.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 EGO31089.1 - 0.0024 17.9 1.7 0.0024 17.9 1.7 2.1 2 0 0 2 2 2 1 TolA binding protein trimerisation DUF4482 PF14818.6 EGO31089.1 - 0.0033 18.3 0.4 0.0062 17.4 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4482) Peptidase_C21 PF05381.12 EGO31089.1 - 0.0078 16.5 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 Tymovirus endopeptidase FapA PF03961.13 EGO31089.1 - 0.012 14.3 1.4 0.014 14.0 1.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc29 PF17082.5 EGO31089.1 - 0.025 14.4 4.1 0.033 14.1 4.1 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 Mt_ATP-synt_B PF05405.14 EGO31089.1 - 0.047 13.3 1.8 0.06 13.0 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FlaC_arch PF05377.11 EGO31089.1 - 0.067 13.6 0.4 0.13 12.7 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 EGO31089.1 - 0.089 12.8 6.6 0.11 12.5 6.6 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 EGO31089.1 - 0.13 11.5 4.8 0.051 12.9 1.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EMP24_GP25L PF01105.24 EGO31089.1 - 0.54 10.2 2.3 0.71 9.8 2.3 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 EGO31089.1 - 8.1 6.3 9.2 4.8 7.0 2.3 2.2 1 1 1 2 2 2 0 Septum formation initiator HLH PF00010.26 EGO31092.1 - 1.3e-09 37.9 2.3 1.3e-09 37.9 2.3 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain UPF0242 PF06785.11 EGO31092.1 - 0.12 12.5 3.8 0.15 12.1 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TBCA PF02970.16 EGO31094.1 - 1.4e-22 79.8 5.9 5.4e-22 77.9 5.9 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor A Med11 PF10280.9 EGO31095.1 - 0.00015 22.3 0.2 0.00056 20.4 0.2 2.0 1 1 0 1 1 1 1 Mediator complex protein Bromodomain PF00439.25 EGO31096.1 - 6.8e-54 179.9 0.1 2e-19 69.4 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 EGO31096.1 - 7.5e-10 38.7 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGO31096.1 - 6.8e-05 23.1 0.2 0.11 12.6 0.0 2.8 2 1 1 3 3 3 2 Peptidase M1 N-terminal domain PIP5K PF01504.18 EGO31097.1 - 2.3e-46 158.2 0.6 1.1e-37 129.8 0.4 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGO31097.1 - 3.9e-28 98.3 0.0 6e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EGO31097.1 - 0.013 15.6 0.9 0.05 13.7 0.4 2.1 2 0 0 2 2 2 0 FYVE zinc finger Methyltransf_33 PF10017.9 EGO31098.1 - 7.1e-79 265.2 0.0 8.4e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent PCI PF01399.27 EGO31099.1 - 2.2e-17 63.5 0.9 7.5e-17 61.8 0.5 2.1 1 1 1 2 2 2 1 PCI domain DUF5517 PF17639.2 EGO31099.1 - 0.028 14.7 1.8 0.028 14.7 1.8 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5517) MRP-L28 PF09812.9 EGO31100.1 - 3.3e-10 40.3 7.0 1.7e-07 31.5 4.2 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 Takusan PF04822.13 EGO31100.1 - 0.39 10.6 4.9 0.64 9.9 4.9 1.3 1 0 0 1 1 1 0 Takusan Rsm22 PF09243.10 EGO31101.1 - 8.2e-44 149.9 0.0 6.5e-29 101.0 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.29 EGO31102.1 - 1e-26 94.0 0.0 1.6e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGO31102.1 - 1.9e-09 37.7 0.1 3.6e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 EGO31102.1 - 0.6 9.9 2.3 0.72 9.6 1.0 1.8 2 0 0 2 2 2 0 Variant UBP zinc finger dsrm PF00035.26 EGO31104.1 - 7.8e-08 32.9 0.0 9.3e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 EGO31105.1 - 8.7e-07 29.6 0.0 1.1e-06 29.2 0.0 1.3 1 1 0 1 1 1 1 Double-stranded RNA binding motif MARVEL PF01284.23 EGO31107.1 - 1e-06 28.9 21.1 1e-06 28.9 21.1 1.6 1 1 1 2 2 2 1 Membrane-associating domain UL73_N PF12522.8 EGO31107.1 - 1.6 8.5 7.9 0.1 12.4 2.0 2.2 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal DUF2070 PF09843.9 EGO31107.1 - 2.9 6.1 18.5 3.9 5.6 18.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4834 PF16118.5 EGO31107.1 - 3.4 8.7 0.0 3.4 8.7 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Nodulin_late PF07127.11 EGO31107.1 - 4.8 7.6 6.3 1.8 9.0 0.5 2.4 2 0 0 2 2 2 0 Late nodulin protein WD40 PF00400.32 EGO31108.1 - 2e-40 136.0 20.7 2.2e-07 31.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO31108.1 - 2.4e-16 59.8 0.0 0.0033 17.7 0.0 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO31108.1 - 0.00071 18.6 0.5 1.9 7.3 0.0 3.7 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO31108.1 - 0.00098 19.0 0.0 0.41 10.5 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO31108.1 - 0.00099 18.5 0.0 0.29 10.4 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 EGO31108.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF1730 PF08331.10 EGO31109.1 - 0.058 13.3 0.1 0.065 13.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1730) DUF1773 PF08593.10 EGO31110.1 - 1.8 9.7 7.3 0.35 11.9 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function SIKE PF05769.11 EGO31114.1 - 2.8e-07 30.6 11.6 1.5e-06 28.2 6.9 2.7 3 0 0 3 3 3 2 SIKE family DUF535 PF04393.13 EGO31114.1 - 0.24 10.6 5.4 0.056 12.7 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF535) NCBP3 PF10309.9 EGO31115.1 - 5.8e-06 26.1 0.0 8.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EGO31115.1 - 0.0026 17.7 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain HTH_17 PF12728.7 EGO31117.1 - 0.0024 18.0 0.0 0.003 17.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_23 PF13489.6 EGO31118.1 - 1.4e-09 38.1 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO31118.1 - 1.8e-09 38.1 0.0 1.5e-08 35.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO31118.1 - 8.3e-08 32.9 0.0 3.1e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO31118.1 - 4.3e-07 29.8 0.0 1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO31118.1 - 6.5e-07 29.9 0.0 2e-06 28.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EGO31118.1 - 0.00028 21.1 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGO31118.1 - 0.00071 19.1 0.0 0.0022 17.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EGO31118.1 - 0.0079 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EGO31118.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EGO31118.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EGO31118.1 - 0.077 12.3 0.0 0.52 9.6 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EGO31118.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase DSHCT PF08148.12 EGO31119.1 - 4.6e-52 176.0 0.5 1.1e-51 174.8 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EGO31119.1 - 7.9e-35 119.6 0.0 1.5e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EGO31119.1 - 5.4e-26 92.1 0.1 8.2e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EGO31119.1 - 1.5e-19 70.5 0.1 3e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO31119.1 - 1.5e-06 28.3 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO31119.1 - 7e-05 23.1 0.0 0.00028 21.2 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Methyltransf_23 PF13489.6 EGO31122.1 - 3.5e-07 30.2 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO31122.1 - 7.3e-07 29.8 0.0 3.1e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO31122.1 - 3.1e-06 27.9 0.0 8.9e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO31122.1 - 9.9e-05 22.2 0.0 0.0013 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGO31122.1 - 0.00046 20.3 0.0 0.00072 19.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGO31122.1 - 0.0007 19.1 0.0 0.002 17.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 EGO31122.1 - 0.00081 20.0 0.0 0.0022 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO31122.1 - 0.041 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EGO31122.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ist1 PF03398.14 EGO31124.1 - 2.1e-33 115.6 0.0 3.1e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Plavaka PF18759.1 EGO31125.1 - 9.2e-41 140.1 0.1 9.2e-41 140.1 0.1 2.1 2 0 0 2 2 2 1 Plavaka transposase FrhB_FdhB_C PF04432.13 EGO31125.1 - 0.17 11.7 2.2 0.48 10.2 0.1 2.4 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Cytochrom_D1 PF02239.16 EGO31128.1 - 0.04 12.4 0.0 0.047 12.2 0.0 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain RasGEF PF00617.19 EGO31129.1 - 4.8e-40 137.6 0.0 8.5e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO31129.1 - 2.4e-22 79.2 0.1 6.3e-22 77.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EGO31130.1 - 4.8e-58 195.3 0.1 5.5e-58 195.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO31130.1 - 7e-36 123.1 0.0 9.2e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO31130.1 - 5.8e-13 48.7 0.1 6.7e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO31130.1 - 3e-06 26.7 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO31130.1 - 6.3e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO31130.1 - 1e-05 25.5 0.2 0.15 11.9 0.0 2.6 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EGO31130.1 - 2.2e-05 24.1 0.0 5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGO31130.1 - 0.0071 16.7 0.1 0.015 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EGO31130.1 - 0.048 13.1 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EGO31130.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein RRM_1 PF00076.22 EGO31131.1 - 5.4e-15 55.0 0.0 6.4e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO31131.1 - 0.12 12.4 0.3 5.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1534 PF07551.11 EGO31131.1 - 0.24 11.2 2.5 0.71 9.7 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) MatE PF01554.18 EGO31132.1 - 4.2e-25 88.3 25.6 4.6e-17 62.1 6.5 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGO31132.1 - 2.6e-06 27.6 0.3 2.6e-06 27.6 0.3 3.6 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain polyprenyl_synt PF00348.17 EGO31135.1 - 6.9e-63 212.1 0.0 8.6e-58 195.4 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase Calreticulin PF00262.18 EGO31136.1 - 1.1e-158 527.9 7.8 1.6e-158 527.4 7.8 1.2 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 EGO31136.1 - 1.4e-45 155.2 0.1 2.3e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EGO31136.1 - 2.6e-36 124.9 3.0 6.7e-36 123.6 3.0 1.7 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EGO31136.1 - 9.3e-23 80.3 0.0 2.3e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGO31136.1 - 1.3e-21 76.4 0.0 2.5e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO31136.1 - 1.6e-09 38.0 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO31136.1 - 5.8e-06 26.4 0.1 1.1e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EGO31136.1 - 1.5e-05 25.0 0.0 8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.10 EGO31136.1 - 0.0072 15.8 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EGO31136.1 - 0.13 12.3 1.2 5.1 7.1 0.2 2.6 2 1 1 3 3 3 0 Dynamin family Prefoldin_2 PF01920.20 EGO31137.1 - 8.7e-17 61.0 7.0 1.1e-16 60.7 7.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 EGO31137.1 - 0.005 17.0 0.7 0.005 17.0 0.7 2.2 2 0 0 2 2 2 1 Tropomyosin like DHR10 PF18595.1 EGO31137.1 - 0.0099 15.9 6.9 0.055 13.5 0.7 2.3 2 1 0 2 2 2 2 Designed helical repeat protein 10 domain Mei5 PF10376.9 EGO31137.1 - 0.015 15.2 3.5 0.019 14.8 3.5 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein NCA2 PF08637.10 EGO31137.1 - 0.041 13.1 3.9 1.4 8.0 0.4 2.0 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 Coat_F PF07875.12 EGO31137.1 - 0.093 13.0 1.9 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Coat F domain DUF5320 PF17253.2 EGO31137.1 - 0.096 13.8 2.1 0.23 12.5 0.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) OmpH PF03938.14 EGO31137.1 - 5.5 7.3 15.6 0.51 10.7 3.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ABC2_membrane PF01061.24 EGO31138.1 - 4.7e-65 218.9 56.4 2.9e-35 121.6 16.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGO31138.1 - 4e-32 111.6 0.0 4.6e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGO31138.1 - 2.7e-23 81.7 0.9 3e-16 59.1 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGO31138.1 - 1.1e-10 42.0 0.0 3.2e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 EGO31138.1 - 1.2e-05 25.9 0.0 0.003 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO31138.1 - 8.3e-05 22.8 0.0 0.032 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO31138.1 - 0.00022 21.7 0.2 0.039 14.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO31138.1 - 0.00023 21.4 0.6 0.6 10.4 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.6 EGO31138.1 - 0.0003 21.2 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGO31138.1 - 0.00041 20.0 0.0 0.74 9.4 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EGO31138.1 - 0.0034 17.7 0.0 0.4 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGO31138.1 - 0.0048 16.7 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGO31138.1 - 0.016 15.1 0.0 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGO31138.1 - 0.018 14.8 0.2 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGO31138.1 - 0.018 14.6 0.2 0.27 10.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGO31138.1 - 0.025 14.0 0.0 0.63 9.4 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 EGO31138.1 - 0.048 14.0 0.9 2.6 8.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGO31138.1 - 0.053 13.2 1.5 4.8 6.8 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGO31138.1 - 0.08 13.4 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4600 PF15372.6 EGO31140.1 - 0.008 16.6 3.4 0.023 15.1 3.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) CREPT PF16566.5 EGO31140.1 - 0.065 13.4 9.8 0.019 15.1 5.9 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 EGO31140.1 - 1.1 9.2 6.5 0.75 9.8 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.6 EGO31140.1 - 3.8 7.0 22.3 2.8 7.4 7.8 3.0 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF4201 PF13870.6 EGO31140.1 - 5.3 6.7 18.0 0.84 9.3 8.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 EGO31140.1 - 5.3 7.1 23.0 0.53 10.3 0.8 4.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 EGO31140.1 - 7.4 7.3 14.3 7.6 7.2 0.3 4.1 4 1 0 4 4 4 0 Initiation control protein YabA EF-hand_6 PF13405.6 EGO31141.1 - 7.5e-10 37.9 0.3 0.0013 18.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGO31141.1 - 4.3e-08 32.3 0.4 3.3e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EGO31141.1 - 6.5e-07 28.4 0.4 6.1e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGO31141.1 - 8.2e-07 29.4 0.6 8.2e-07 29.4 0.6 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EGO31141.1 - 0.0027 17.5 0.1 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair Dopey_N PF04118.14 EGO31142.1 - 3e-110 368.2 6.6 3.1e-110 368.1 0.0 3.6 5 0 0 5 5 5 1 Dopey, N-terminal ATP-synt_E PF05680.12 EGO31145.1 - 1.2e-19 70.5 0.2 1.4e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain CAF1C_H4-bd PF12265.8 EGO31146.1 - 8e-29 99.7 1.0 1.6e-28 98.8 0.4 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGO31146.1 - 7.2e-16 58.3 14.0 6.8e-05 23.6 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Frtz PF11768.8 EGO31146.1 - 9.5e-06 24.2 0.0 1.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 EGO31146.1 - 0.0012 19.0 0.2 0.17 12.2 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PA_decarbox PF05870.11 EGO31146.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) RAMP4 PF06624.12 EGO31147.1 - 1.2e-11 44.5 0.4 1.5e-11 44.2 0.4 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3040 PF11239.8 EGO31147.1 - 0.0034 17.6 0.0 0.0037 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) DUF5056 PF16479.5 EGO31147.1 - 0.0063 16.7 0.0 0.0088 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5056) PAP_PilO PF06864.12 EGO31147.1 - 0.07 11.9 0.0 0.08 11.8 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2431 PF10354.9 EGO31148.1 - 7e-54 182.6 0.0 1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltr_RsmB-F PF01189.17 EGO31148.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DASH_Spc19 PF08287.11 EGO31148.1 - 5.4 6.9 9.8 0.33 10.8 4.6 1.5 2 0 0 2 2 2 0 Spc19 Fip1 PF05182.13 EGO31149.1 - 1.2e-20 72.7 0.8 2.1e-20 71.9 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif adh_short PF00106.25 EGO31150.1 - 1.5e-24 86.5 1.3 2.2e-24 86.0 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO31150.1 - 1.8e-21 76.8 2.8 6.5e-21 75.0 2.7 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO31150.1 - 1.5e-07 31.5 0.1 2.3e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO31150.1 - 8.5e-06 25.8 0.9 1.3e-05 25.2 0.9 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO31150.1 - 0.0011 18.5 1.9 0.034 13.6 1.9 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO31150.1 - 0.0018 17.8 0.6 0.0035 16.9 0.6 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EGO31150.1 - 0.0026 18.0 0.1 0.0057 16.9 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Xol-1_N PF09108.10 EGO31150.1 - 0.028 14.3 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal ING PF12998.7 EGO31151.1 - 4.6e-15 56.0 0.1 7.1e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGO31151.1 - 1.5e-05 24.7 5.9 2.4e-05 24.1 5.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGO31151.1 - 0.06 12.9 2.1 0.1 12.1 2.1 1.3 1 0 0 1 1 1 0 PHD-finger MFS_1 PF07690.16 EGO31153.1 - 3.3e-20 72.3 27.4 5.3e-20 71.7 27.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PGF-CTERM PF18204.1 EGO31153.1 - 0.37 10.8 7.3 2.3 8.3 1.3 2.7 2 0 0 2 2 2 0 PGF-CTERM motif RabGAP-TBC PF00566.18 EGO31155.1 - 1.5e-48 165.4 0.0 1.9e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.33 EGO31157.1 - 2.3e-06 27.3 0.2 2.3e-06 27.3 0.2 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGO31157.1 - 6.1e-05 22.8 0.3 0.0007 19.4 0.1 2.9 2 1 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EGO31157.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.2 5 0 0 5 5 5 0 F-box ParA PF10609.9 EGO31158.1 - 6.7e-88 294.3 0.0 8e-88 294.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGO31158.1 - 3.6e-08 33.5 0.0 5.1e-07 29.8 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EGO31158.1 - 3e-07 29.9 1.8 0.00027 20.2 0.2 3.0 3 0 0 3 3 3 2 Anion-transporting ATPase AAA_31 PF13614.6 EGO31158.1 - 2.3e-05 24.4 0.0 0.0098 15.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EGO31158.1 - 0.00017 21.0 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 EGO31158.1 - 0.12 11.9 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_22 PF13401.6 EGO31158.1 - 0.12 12.6 0.1 0.34 11.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.22 EGO31162.1 - 4.3e-16 58.5 0.0 8.1e-11 41.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO31162.1 - 0.085 13.0 0.1 13 6.0 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif RNA_pol_Rpb6 PF01192.22 EGO31163.1 - 5.4e-15 55.0 0.1 7.8e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.17 EGO31164.1 - 1.3e-33 116.4 0.0 1.9e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Ribonuclease_T2 PF00445.18 EGO31165.1 - 4.2e-38 131.4 0.1 5.7e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Ig_4 PF16680.5 EGO31166.1 - 0.073 13.3 0.3 0.083 13.2 0.3 1.1 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Herpes_UL6 PF01763.16 EGO31168.1 - 0.0066 15.0 0.1 0.01 14.4 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like RNF220 PF15926.5 EGO31168.1 - 0.55 9.8 4.7 9.4 5.8 0.2 2.4 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Jnk-SapK_ap_N PF09744.9 EGO31168.1 - 2.6 8.2 6.1 0.39 10.9 0.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SURF1 PF02104.15 EGO31170.1 - 7e-46 156.7 0.0 8.8e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family PsbK PF02533.15 EGO31170.1 - 0.13 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component ANTH PF07651.16 EGO31171.1 - 9.6e-72 241.3 3.3 1.8e-71 240.4 0.0 2.8 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EGO31171.1 - 2.6e-54 183.6 8.3 2.6e-54 183.6 8.3 5.0 5 1 1 6 6 6 2 I/LWEQ domain ENTH PF01417.20 EGO31171.1 - 0.00021 21.4 0.1 0.009 16.1 0.0 3.3 2 0 0 2 2 2 1 ENTH domain TcdB_N PF12918.7 EGO31171.1 - 0.03 14.6 0.0 0.15 12.4 0.0 2.3 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain FAA_hydro_N_2 PF18288.1 EGO31171.1 - 0.034 14.5 2.0 0.36 11.3 0.7 3.4 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 XkdW PF09636.10 EGO31171.1 - 2.6 8.2 7.3 0.78 9.9 2.3 2.7 2 0 0 2 2 2 0 XkdW protein Ion_trans PF00520.31 EGO31175.1 - 1.4e-05 24.4 3.1 1.8e-05 24.1 3.1 1.1 1 0 0 1 1 1 1 Ion transport protein Epimerase PF01370.21 EGO31178.1 - 9.2e-12 44.9 0.0 3.3e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO31178.1 - 1.8e-10 40.3 0.0 1.4e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO31178.1 - 3.6e-10 39.4 0.0 3.5e-05 23.1 0.0 2.6 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGO31178.1 - 4.5e-07 29.9 0.0 7.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO31178.1 - 0.0018 17.5 0.0 0.013 14.7 0.0 2.1 2 1 1 3 3 3 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EGO31178.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 EGO31178.1 - 0.085 13.7 0.1 0.27 12.1 0.0 1.9 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NmrA PF05368.13 EGO31178.1 - 0.14 11.7 0.1 0.25 10.9 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 EGO31178.1 - 0.18 11.7 0.1 0.37 10.6 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 EGO31179.1 - 7.1e-47 160.0 29.8 7.1e-47 160.0 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO31179.1 - 1.3e-07 30.9 13.5 1.3e-07 30.9 13.5 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EGO31179.1 - 6e-07 28.2 5.7 1.1e-06 27.4 5.7 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.13 EGO31179.1 - 7.2e-07 28.0 4.8 7.2e-07 28.0 4.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 EGO31179.1 - 0.0064 15.2 7.7 0.02 13.6 1.1 2.5 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EGO31179.1 - 0.016 14.1 10.7 0.031 13.1 7.3 2.5 1 1 0 1 1 1 0 MFS_1 like family HORMA PF02301.18 EGO31180.1 - 8e-08 32.1 0.0 1.2e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 HORMA domain PX PF00787.24 EGO31181.1 - 5.7e-19 68.2 0.3 2.7e-18 66.0 0.3 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGO31181.1 - 0.00084 19.0 3.3 0.0031 17.1 1.3 2.3 2 1 0 2 2 2 1 Vps5 C terminal like Fructosamin_kin PF03881.14 EGO31182.1 - 9.8e-64 215.3 0.0 1.2e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EGO31182.1 - 5e-07 29.9 0.0 8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Oxidored_FMN PF00724.20 EGO31183.1 - 3.2e-61 207.5 0.0 5.7e-61 206.7 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ABC1 PF03109.16 EGO31184.1 - 2e-21 76.3 0.0 1.4e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 ABC1 family DDE_Tnp_ISL3 PF01610.17 EGO31186.1 - 0.0037 17.0 0.1 0.0059 16.3 0.1 1.3 1 0 0 1 1 1 1 Transposase MULE PF10551.9 EGO31186.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 MULE transposase domain F-box-like PF12937.7 EGO31189.1 - 7.4e-05 22.6 0.2 0.00015 21.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like HTH_20 PF12840.7 EGO31189.1 - 0.034 14.2 0.3 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain GPI-anchored PF10342.9 EGO31189.1 - 0.084 13.6 0.0 0.33 11.7 0.0 1.9 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dor1 PF04124.12 EGO31193.1 - 1.3e-35 122.8 3.2 7.6e-28 97.2 4.6 2.4 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 EGO31193.1 - 0.012 15.6 0.0 0.039 14.0 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 MMU163 PF17119.5 EGO31193.1 - 5.4 6.1 5.7 18 4.4 5.7 1.8 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis F-box-like PF12937.7 EGO31194.1 - 0.016 15.1 0.3 0.051 13.5 0.3 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGO31194.1 - 0.023 14.6 0.7 0.023 14.6 0.7 2.6 3 0 0 3 3 3 0 F-box domain F-box_4 PF15966.5 EGO31194.1 - 0.029 14.3 0.6 1.1 9.1 0.1 2.8 3 0 0 3 3 3 0 F-box zf-UBP PF02148.19 EGO31194.1 - 0.056 13.8 0.6 0.056 13.8 0.6 2.2 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein P3A PF08727.11 EGO31194.1 - 0.1 12.0 0.2 0.31 10.5 0.2 1.8 1 0 0 1 1 1 0 Poliovirus 3A protein like Eco57I PF07669.11 EGO31194.1 - 0.11 13.0 0.1 0.33 11.5 0.1 1.8 1 0 0 1 1 1 0 Eco57I restriction-modification methylase DUF1068 PF06364.12 EGO31195.1 - 0.057 13.3 1.3 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) zf-UBP PF02148.19 EGO31195.1 - 0.096 13.0 5.7 0.45 10.9 5.4 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Rep_fac_C PF08542.11 EGO31196.1 - 8e-26 90.3 0.0 2e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGO31196.1 - 2.3e-12 47.4 0.0 3.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGO31196.1 - 4e-12 46.2 0.1 4.5e-10 39.5 0.2 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EGO31196.1 - 5.2e-07 29.8 0.0 7.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO31196.1 - 2.6e-06 27.7 0.0 0.0028 17.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO31196.1 - 3.9e-06 27.3 0.0 0.00031 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EGO31196.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO31196.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EGO31196.1 - 0.00026 20.8 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EGO31196.1 - 0.00079 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EGO31196.1 - 0.0011 18.4 0.0 0.028 13.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EGO31196.1 - 0.0042 16.1 0.0 0.0088 15.1 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EGO31196.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EGO31196.1 - 0.0086 16.4 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 EGO31196.1 - 0.0086 15.9 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit NTPase_1 PF03266.15 EGO31196.1 - 0.027 14.4 0.1 0.09 12.7 0.1 1.8 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.6 EGO31196.1 - 0.041 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO31196.1 - 0.046 14.1 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGO31196.1 - 0.053 13.9 0.2 0.86 9.9 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO31196.1 - 0.073 13.6 0.0 0.57 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGO31196.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain B12-binding_2 PF02607.17 EGO31196.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain TniB PF05621.11 EGO31196.1 - 0.14 11.5 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein KTI12 PF08433.10 EGO31196.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 EGO31196.1 - 0.18 12.3 0.0 0.53 10.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2b PF00587.25 EGO31198.1 - 1e-22 81.0 0.0 2.7e-22 79.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGO31198.1 - 1.4e-09 38.1 1.0 2.2e-09 37.5 1.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 EGO31198.1 - 0.22 12.1 1.0 0.44 11.1 1.0 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Abhydrolase_3 PF07859.13 EGO31200.1 - 1.8e-13 50.8 0.0 2.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO31200.1 - 7.1e-09 35.0 0.2 1.1e-08 34.3 0.2 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EGO31200.1 - 0.15 12.7 0.9 0.17 12.5 0.9 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family STE3 PF02076.15 EGO31201.1 - 1.3e-54 185.4 14.5 1.5e-54 185.2 14.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 EGO31203.1 - 2.8e-85 286.0 19.2 3.3e-85 285.8 19.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Ndc1_Nup PF09531.10 EGO31204.1 - 0.16 10.7 5.7 0.24 10.1 5.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sugar_tr PF00083.24 EGO31205.1 - 1.2e-124 416.6 16.1 1.5e-124 416.3 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO31205.1 - 1.7e-16 60.1 50.2 9.3e-16 57.7 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily nec1 PF10379.9 EGO31206.1 - 0.042 13.3 0.6 0.13 11.7 0.4 1.8 1 1 1 2 2 2 0 Virulence protein nec1 DUF3099 PF11298.8 EGO31207.1 - 3.9 7.7 5.7 6 7.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Inositol_P PF00459.25 EGO31208.1 - 7.5e-67 225.7 0.0 8.8e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family G-alpha PF00503.20 EGO31209.1 - 2e-114 382.5 0.0 2.5e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO31209.1 - 2.2e-13 50.0 0.1 2.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGO31209.1 - 2.5e-05 24.4 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGO31209.1 - 0.00092 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein GTP_EFTU PF00009.27 EGO31209.1 - 0.0053 16.3 0.0 0.091 12.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 EGO31209.1 - 0.0095 15.5 0.0 2.4 7.8 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_29 PF13555.6 EGO31209.1 - 0.016 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 EGO31209.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 EGO31209.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EGO31209.1 - 0.21 10.9 1.0 9.4 5.5 0.2 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.24 EGO31213.1 - 6.2e-124 414.3 15.8 7e-124 414.1 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO31213.1 - 4.6e-20 71.9 47.7 4.2e-18 65.4 21.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.21 EGO31214.1 - 6.6e-40 135.9 0.0 7.4e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DASH_Ask1 PF08655.10 EGO31215.1 - 4.6e-24 84.1 0.2 8.7e-24 83.2 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Dus PF01207.17 EGO31216.1 - 2.2e-51 174.8 0.0 4.5e-51 173.8 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) XPC-binding PF09280.11 EGO31216.1 - 0.087 12.6 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 XPC-binding domain Lipoprotein_2 PF00921.17 EGO31216.1 - 0.2 11.2 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Borrelia lipoprotein ADH_zinc_N PF00107.26 EGO31217.1 - 1.5e-11 44.3 0.1 3.5e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO31217.1 - 8.5e-08 32.0 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGO31217.1 - 0.00031 21.8 0.0 0.00066 20.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CPSase_L_D2 PF02786.17 EGO31218.1 - 2.8e-73 245.9 0.0 4.4e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGO31218.1 - 5e-42 142.9 0.3 1.6e-41 141.2 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGO31218.1 - 1.6e-30 105.4 0.0 3.7e-23 81.7 0.0 2.5 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGO31218.1 - 9e-17 60.7 3.3 1.9e-16 59.7 3.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGO31218.1 - 1.3e-10 41.2 0.0 2.8e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGO31218.1 - 6.1e-10 38.9 0.2 2.5e-09 37.0 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGO31218.1 - 2e-07 30.7 0.7 0.00023 20.9 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 EGO31218.1 - 0.00026 20.9 0.8 0.011 15.7 0.5 2.7 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 EGO31218.1 - 0.00082 20.0 0.3 0.97 10.2 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EGO31218.1 - 0.0018 17.6 0.5 0.5 9.5 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EGO31218.1 - 0.0072 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 EGO31218.1 - 0.0081 16.1 0.6 0.016 15.1 0.6 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein GARS_A PF01071.19 EGO31218.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ntox43 PF15537.6 EGO31218.1 - 0.018 15.1 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 43 NQRA PF05896.11 EGO31218.1 - 0.042 13.3 0.6 0.076 12.4 0.6 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 EGO31218.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PYNP_C PF07831.13 EGO31218.1 - 0.064 12.9 1.1 0.36 10.5 0.1 2.6 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATPgrasp_ST PF14397.6 EGO31218.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Exo84_C PF16528.5 EGO31220.1 - 9.2e-40 136.7 0.6 4.8e-39 134.3 0.6 2.2 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGO31220.1 - 7.8e-17 61.1 0.4 2.5e-16 59.5 0.4 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 EGO31220.1 - 6.3e-06 26.3 2.3 6.3e-06 26.3 2.3 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DNA_methylase PF00145.17 EGO31222.1 - 1.9e-36 126.1 0.0 9.5e-36 123.8 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EGO31222.1 - 1.9e-15 56.8 0.0 4.7e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 EGO31222.1 - 2e-07 31.2 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Pkinase PF00069.25 EGO31223.1 - 1.1e-66 224.9 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO31223.1 - 1.1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO31223.1 - 7.3e-06 25.2 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO31223.1 - 0.00073 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO31223.1 - 0.00073 18.9 0.0 0.002 17.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO31223.1 - 0.0031 16.9 0.0 0.051 12.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EGO31223.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGO31223.1 - 0.019 14.6 0.1 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family NAD_binding_1 PF00175.21 EGO31224.1 - 2.9e-27 95.4 0.0 5.1e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGO31224.1 - 8.5e-19 67.8 0.0 1.7e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGO31224.1 - 0.00037 20.7 0.0 0.003 17.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGO31224.1 - 0.0059 16.8 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain UCH PF00443.29 EGO31225.1 - 2.3e-38 132.2 0.0 4.8e-38 131.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EGO31225.1 - 3.9e-22 77.9 0.5 8.1e-16 57.7 0.1 2.9 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 EGO31225.1 - 1e-07 31.9 0.1 0.0095 15.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase efThoc1 PF11957.8 EGO31226.1 - 8.2e-93 311.7 9.5 3.7e-87 293.1 0.9 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor GDP_Man_Dehyd PF16363.5 EGO31226.1 - 2.6e-32 112.5 0.0 6.5e-32 111.2 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO31226.1 - 4e-32 111.6 0.0 8.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO31226.1 - 9.3e-07 28.1 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO31226.1 - 2.7e-05 23.4 0.1 5.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO31226.1 - 0.00038 19.7 0.0 0.00081 18.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Atrophin-1 PF03154.15 EGO31226.1 - 0.0011 17.4 5.2 0.0011 17.4 5.2 2.6 3 0 0 3 3 2 1 Atrophin-1 family DUF3915 PF13054.6 EGO31226.1 - 0.017 15.1 1.7 0.038 14.0 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) BSP_II PF05432.11 EGO31226.1 - 0.042 13.5 7.6 0.083 12.6 7.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) KR PF08659.10 EGO31226.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 KR domain Folliculin PF11704.8 EGO31226.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Phage_Gp23 PF10669.9 EGO31226.1 - 7.3 7.0 7.5 20 5.5 7.5 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Rotamase PF00639.21 EGO31227.1 - 4.3e-21 75.7 0.0 5.6e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGO31227.1 - 2e-18 67.0 0.0 3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EGO31227.1 - 1.7e-08 34.4 0.8 4.4e-08 33.1 0.2 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EGO31227.1 - 0.0026 18.6 0.0 0.0035 18.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MOSC PF03473.17 EGO31228.1 - 1.9e-21 76.4 0.0 3.3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGO31228.1 - 2.8e-16 59.5 0.0 4.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF1184 PF06683.11 EGO31228.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) UCH PF00443.29 EGO31229.1 - 4.9e-44 150.7 0.2 5.4e-44 150.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO31229.1 - 1.2e-22 81.0 0.1 1.4e-22 80.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGO31229.1 - 0.022 14.2 5.2 0.068 12.6 2.4 2.4 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Med10 PF09748.9 EGO31229.1 - 0.03 14.3 0.1 7.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex RTP PF02334.16 EGO31232.1 - 0.042 14.5 0.0 3.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Replication terminator protein MerR-DNA-bind PF09278.11 EGO31232.1 - 0.18 12.4 0.8 0.6 10.7 0.1 2.2 3 0 0 3 3 3 0 MerR, DNA binding APH PF01636.23 EGO31233.1 - 1.8e-12 47.7 0.3 2.7e-12 47.1 0.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO31233.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGO31233.1 - 0.056 12.8 0.0 1.6 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 EGO31233.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EGO31233.1 - 0.23 10.7 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RRM_1 PF00076.22 EGO31235.1 - 1.5e-17 63.1 0.0 2.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO31235.1 - 0.027 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1115 PF06544.12 EGO31236.1 - 5e-05 23.4 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 EGO31236.1 - 0.00067 19.9 0.1 0.0021 18.4 0.0 1.9 2 0 0 2 2 2 1 RWD domain DUF726 PF05277.12 EGO31238.1 - 1.1e-120 402.7 0.4 1.6e-120 402.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 EGO31238.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3541 PF12060.8 EGO31238.1 - 0.1 12.3 0.6 0.18 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Ferritin_2 PF13668.6 EGO31238.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain SRP14 PF02290.15 EGO31239.1 - 6.7e-25 87.3 3.7 2.5e-24 85.5 0.1 2.2 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Polyhedrin PF00738.18 EGO31239.1 - 0.1 11.9 0.8 0.14 11.5 0.8 1.3 1 0 0 1 1 1 0 Polyhedrin gag_pre-integrs PF13976.6 EGO31239.1 - 0.12 12.2 0.2 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 GAG-pre-integrase domain TP_methylase PF00590.20 EGO31240.1 - 5.9e-42 144.0 1.1 5.9e-42 144.0 1.1 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 EGO31240.1 - 0.00019 21.0 0.8 0.00035 20.1 0.8 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Pkinase PF00069.25 EGO31241.1 - 3e-19 69.4 0.0 3.9e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO31241.1 - 7.3e-15 55.0 0.0 8.7e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO31241.1 - 0.0022 17.3 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ank_4 PF13637.6 EGO31242.1 - 3.8e-13 49.7 0.2 1.1e-07 32.3 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO31242.1 - 4.8e-13 49.0 1.7 3.1e-05 24.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGO31242.1 - 1e-12 47.9 0.3 8e-06 26.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EGO31242.1 - 1.5e-10 41.5 0.4 1.4e-09 38.4 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO31242.1 - 1.9e-10 40.0 0.8 4.3e-05 23.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat p450 PF00067.22 EGO31243.1 - 1.5e-45 155.8 0.0 1.9e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DMSP_lyase PF16867.5 EGO31247.1 - 0.13 11.9 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DIOX_N PF14226.6 EGO31248.1 - 1.5e-16 61.2 0.0 2.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO31248.1 - 9.3e-14 51.7 0.0 2.6e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAD-oxidase_C PF02913.19 EGO31249.1 - 3.6e-51 174.2 0.0 4.6e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO31249.1 - 1e-34 119.3 0.4 1.8e-34 118.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.11 EGO31249.1 - 0.00099 18.5 0.1 0.032 13.6 0.1 2.2 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding LSM PF01423.22 EGO31250.1 - 1.9e-17 62.7 0.2 2.6e-17 62.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGO31250.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Hfq protein SET PF00856.28 EGO31252.1 - 1.5e-09 38.4 0.0 2.8e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 SET domain DUF829 PF05705.14 EGO31253.1 - 0.12 12.3 0.2 0.12 12.2 0.2 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Rhomboid PF01694.22 EGO31254.1 - 1.3e-34 119.4 12.3 2.4e-34 118.5 12.3 1.5 1 0 0 1 1 1 1 Rhomboid family DUF4149 PF13664.6 EGO31254.1 - 0.28 11.5 3.9 10 6.5 0.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Rib_recp_KP_reg PF05104.12 EGO31258.1 - 6.4 7.8 7.6 1.1 10.3 4.2 1.4 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Plavaka PF18759.1 EGO31260.1 - 8.7e-31 107.3 0.1 1.2e-30 106.9 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 EGO31261.1 - 6.2e-128 413.0 50.7 9.5e-10 38.9 0.2 15.3 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO31261.1 - 4.8e-56 187.0 4.0 0.0019 18.5 0.0 13.9 1 1 12 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO31261.1 - 3.6e-29 101.8 14.2 0.032 13.2 0.0 13.5 1 1 12 13 13 13 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO31261.1 - 1.1e-25 89.0 6.0 0.15 12.0 0.0 13.0 13 0 0 13 13 13 5 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EGO31261.1 - 7.1e-10 38.4 16.3 13 5.6 0.0 11.4 12 0 0 12 12 11 0 Proteasome subunit A N-terminal signature Gmad1 PF10647.9 EGO31261.1 - 4e-09 36.6 13.6 0.43 10.3 0.1 8.4 1 1 7 8 8 8 3 Lipoprotein LpqB beta-propeller domain NACHT PF05729.12 EGO31261.1 - 4.9e-09 36.3 0.0 9.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Frtz PF11768.8 EGO31261.1 - 6.1e-09 34.7 0.0 0.22 9.8 0.0 5.9 5 2 0 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EGO31261.1 - 6.2e-08 31.7 7.2 10 4.6 0.0 9.5 6 5 4 11 11 11 0 Nucleoporin Nup120/160 Ret2_MD PF18528.1 EGO31261.1 - 4.1e-06 27.1 0.0 1.2e+02 3.2 0.0 9.6 6 4 6 13 13 12 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nbas_N PF15492.6 EGO31261.1 - 6.1e-06 25.8 8.6 0.49 9.7 0.0 7.8 2 2 2 8 8 8 1 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.15 EGO31261.1 - 6.6e-06 25.2 0.6 1.7 7.3 0.0 6.5 5 3 4 9 9 9 2 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.6 EGO31261.1 - 7e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain WD40_like PF17005.5 EGO31261.1 - 4.3e-05 23.0 0.0 29 3.8 0.0 6.7 7 2 0 7 7 7 0 WD40-like domain nos_propeller PF18764.1 EGO31261.1 - 0.0042 17.0 7.9 30 4.6 0.0 8.1 10 1 0 10 10 10 0 Nitrous oxide reductase propeller repeat AAA PF00004.29 EGO31261.1 - 0.0059 17.0 0.0 0.062 13.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO31261.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Me-amine-dh_H PF06433.11 EGO31261.1 - 0.067 12.0 0.0 0.37 9.6 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Olduvai PF06758.13 EGO31261.1 - 0.073 13.3 0.6 1.1 9.5 0.5 2.6 2 0 0 2 2 2 0 Olduvai domain DUF2075 PF09848.9 EGO31261.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EGO31261.1 - 0.088 12.0 0.0 0.47 9.6 0.0 2.1 1 1 0 1 1 1 0 NB-ARC domain p450 PF00067.22 EGO31262.1 - 4e-51 174.2 0.0 4.6e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 EGO31263.1 - 1.1e-60 200.2 11.9 4.2e-08 33.7 0.1 9.7 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO31263.1 - 3.7e-22 78.4 0.0 0.009 16.3 0.0 8.3 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO31263.1 - 4e-12 45.8 1.2 0.083 11.8 0.0 5.8 3 1 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO31263.1 - 5.8e-08 32.5 6.9 0.11 12.5 0.0 6.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat NACHT PF05729.12 EGO31263.1 - 9.6e-06 25.6 0.0 2.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain C2 PF00168.30 EGO31263.1 - 1.1e-05 25.6 0.0 3.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.6 EGO31263.1 - 0.0004 20.8 0.0 0.0013 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Gmad1 PF10647.9 EGO31263.1 - 0.00079 19.3 2.3 0.076 12.7 0.8 3.7 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 EGO31263.1 - 0.004 16.8 0.6 0.021 14.4 0.1 2.3 1 1 1 2 2 2 1 PQQ-like domain NB-ARC PF00931.22 EGO31263.1 - 0.011 14.9 0.0 0.043 13.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 EGO31263.1 - 0.049 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 EGO31263.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGO31263.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Fasciclin PF02469.22 EGO31264.1 - 4.1e-08 33.5 0.0 6.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Complex1_49kDa PF00346.19 EGO31265.1 - 1.5e-120 401.4 0.0 1.9e-120 401.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EGO31265.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase CIMR PF00878.18 EGO31266.1 - 2.9e-15 56.6 0.1 1.2e-06 28.7 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EGO31266.1 - 2.4e-14 53.0 0.0 3.4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EGO31266.1 - 5.4e-11 42.9 0.0 9.5e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 Baculo_11_kDa PF06143.11 EGO31266.1 - 0.38 10.4 1.7 0.66 9.6 1.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Nramp PF01566.18 EGO31267.1 - 3.7e-87 292.6 19.3 3e-47 161.3 7.6 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Pannexin_like PF12534.8 EGO31267.1 - 0.12 11.4 0.1 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Amidohydro_1 PF01979.20 EGO31270.1 - 2.4e-17 63.3 0.1 3.3e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO31270.1 - 2.2e-12 47.2 0.6 2.5e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Rrp15p PF07890.12 EGO31271.1 - 0.099 13.0 1.6 0.25 11.7 1.6 1.7 1 0 0 1 1 1 0 Rrp15p PUF PF00806.19 EGO31275.1 - 4.5e-19 67.0 1.6 1.2e-06 27.9 0.0 4.5 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat PSCyt1 PF07635.11 EGO31275.1 - 0.15 12.7 0.1 0.46 11.1 0.1 1.9 1 0 0 1 1 1 0 Planctomycete cytochrome C Peptidase_S10 PF00450.22 EGO31276.1 - 8.7e-76 256.0 0.0 1.1e-75 255.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase zf-TRAF_2 PF15965.5 EGO31276.1 - 0.15 12.6 1.4 1.4 9.4 0.7 2.1 1 1 1 2 2 2 0 TRAF-like zinc-finger PARM PF17061.5 EGO31277.1 - 0.012 15.7 1.5 0.017 15.3 1.5 1.2 1 0 0 1 1 1 0 PARM Fez1 PF06818.15 EGO31277.1 - 0.014 15.8 11.2 0.023 15.1 11.2 1.3 1 1 0 1 1 1 0 Fez1 DUF484 PF04340.12 EGO31277.1 - 0.019 14.6 2.7 0.021 14.5 0.3 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF484 Heme_oxygenase PF01126.20 EGO31277.1 - 0.037 13.8 0.2 0.054 13.3 0.2 1.3 1 0 0 1 1 1 0 Heme oxygenase CENP-F_leu_zip PF10473.9 EGO31277.1 - 0.04 13.9 18.5 1.6 8.7 2.0 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 EGO31277.1 - 0.38 10.9 9.8 0.15 12.2 3.8 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EGO31277.1 - 4.2 7.2 14.6 1.7 8.5 0.9 3.1 3 0 0 3 3 3 0 Septum formation initiator zf-MYND PF01753.18 EGO31278.1 - 1.2e-08 34.9 9.3 1.2e-08 34.9 9.3 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EGO31278.1 - 0.058 13.7 7.1 0.16 12.3 7.1 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ecl1 PF12855.7 EGO31278.1 - 0.065 14.4 0.2 0.095 13.9 0.2 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-RING_7 PF02591.15 EGO31278.1 - 0.48 10.7 4.9 2.3 8.5 0.2 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-MYND PF01753.18 EGO31279.1 - 6.7e-08 32.5 10.6 1.5e-07 31.4 10.6 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO31279.1 - 0.0062 16.8 10.4 0.014 15.7 10.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-CCHC PF00098.23 EGO31281.1 - 0.00029 20.8 3.5 0.00051 20.0 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO31281.1 - 0.0045 17.2 0.1 0.0083 16.4 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Baculo_gp41 PF04700.12 EGO31281.1 - 0.034 13.9 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region zf-CCHC_2 PF13696.6 EGO31281.1 - 0.56 10.1 3.1 0.92 9.4 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle TrbL PF04610.14 EGO31282.1 - 0.63 9.8 2.4 1 9.0 1.9 1.6 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Glyco_hydro_3 PF00933.21 EGO31283.1 - 1.4e-51 175.8 0.0 2e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGO31283.1 - 2.3e-48 164.9 0.0 4.3e-48 164.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGO31283.1 - 1.3e-23 82.9 0.4 2.5e-23 81.9 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Dimeth_Pyl PF09505.10 EGO31283.1 - 0.14 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) DUF11 PF01345.18 EGO31283.1 - 0.94 9.8 3.8 0.56 10.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF11 RT_RNaseH PF17917.1 EGO31284.1 - 4.5e-25 88.0 0.3 1e-24 86.8 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EGO31284.1 - 6.2e-25 88.0 0.2 1.8e-24 86.5 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGO31284.1 - 1.2e-19 70.2 0.7 2.8e-13 49.7 0.1 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EGO31284.1 - 1.8e-19 69.6 0.2 4.9e-19 68.2 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGO31284.1 - 5.4e-19 68.5 0.0 1.1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EGO31284.1 - 7.6e-12 45.0 0.2 2.1e-11 43.5 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EGO31284.1 - 3.6e-06 26.8 5.8 8.6e-06 25.6 5.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGO31284.1 - 0.006 16.8 0.2 0.006 16.8 0.2 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EGO31284.1 - 0.0085 16.7 0.0 0.047 14.3 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO31284.1 - 0.013 16.0 0.0 0.069 13.7 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 EGO31284.1 - 0.024 14.4 0.1 0.19 11.6 0.0 2.6 3 0 0 3 3 3 0 Integrase core domain zf-H2C2 PF09337.10 EGO31284.1 - 0.03 14.5 0.8 0.058 13.6 0.0 2.0 2 0 0 2 2 1 0 H2C2 zinc finger RVP_2 PF08284.11 EGO31284.1 - 0.065 13.0 0.2 5.8 6.7 0.0 2.7 2 1 1 3 3 3 0 Retroviral aspartyl protease eIF-4B PF06273.11 EGO31284.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B zf-CCHC_3 PF13917.6 EGO31284.1 - 1.5 8.8 6.7 4.9 7.2 6.7 1.8 1 0 0 1 1 1 0 Zinc knuckle DnaJ PF00226.31 EGO31285.1 - 7e-14 51.7 0.1 1.4e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EGO31285.1 - 1.1e-13 51.0 0.0 4.9e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Sec63 Brl domain Myb_DNA-binding PF00249.31 EGO31285.1 - 0.062 13.5 0.1 5.1 7.4 0.0 3.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain Lig_C PF18330.1 EGO31285.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sel1 PF08238.12 EGO31286.1 - 8.4e-46 153.4 16.1 5.1e-08 33.3 0.1 7.6 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 EGO31286.1 - 0.55 10.5 3.7 2.8 8.2 0.4 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_pol_Rpb2_6 PF00562.28 EGO31287.1 - 4e-127 424.5 0.1 6.1e-127 423.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGO31287.1 - 2.7e-69 232.7 0.0 3.9e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGO31287.1 - 8.2e-48 162.6 0.5 1.9e-47 161.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGO31287.1 - 2.4e-32 111.2 0.4 5.5e-32 110.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EGO31287.1 - 5.4e-26 90.7 1.6 8.4e-26 90.1 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGO31287.1 - 1.7e-25 89.0 0.2 4.2e-25 87.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGO31287.1 - 2.3e-22 79.3 0.3 7e-22 77.7 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EGO31287.1 - 1.9 9.2 4.5 0.64 10.8 0.8 2.1 2 0 0 2 2 2 0 MRN-interacting protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Serpula_lacrymans_var._lacrymans_S7.9-v1.0/GCA_000218685.1_v1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Serpula_lacrymans_var._lacrymans_S7.9-v1.0/GCA_000218685.1_v1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Serpula_lacrymans_var._lacrymans_S7.9-v1.0/GCA_000218685.1_v1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Serpula_lacrymans_var._lacrymans_S7.9-v1.0/GCA_000218685.1_v1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:24:17 2019 # [ok]