# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1342 PF07072.6 EGO18365.1 - 0.027 14.1 0.1 0.031 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) DUF434 PF04256.7 EGO18365.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Transposase_21 PF02992.9 EGO18369.1 - 7.9e-13 48.0 0.2 8.5e-13 47.9 0.1 1.0 1 0 0 1 1 1 1 Transposase family tnp2 COesterase PF00135.23 EGO18370.1 - 6.3e-48 163.7 0.5 9.1e-37 126.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO18370.1 - 0.0044 16.6 0.1 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold YlqD PF11068.3 EGO18371.1 - 0.97 9.4 9.8 1.1 9.2 6.8 1.1 1 0 0 1 1 1 0 YlqD protein DUF4570 PF15134.1 EGO18371.1 - 1.3 8.9 10.2 1.6 8.6 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF1423 PF07227.6 EGO18371.1 - 1.8 7.1 8.6 2.3 6.7 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) CAF-1_p150 PF11600.3 EGO18371.1 - 3.4 7.0 16.7 3.7 6.8 11.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 EGO18371.1 - 5.1 6.3 14.7 5.9 6.1 10.2 1.0 1 0 0 1 1 1 0 SprA-related family VIT1 PF01988.14 EGO18371.1 - 6.2 6.2 8.7 6.3 6.2 6.0 1.0 1 0 0 1 1 1 0 VIT family PP28 PF10252.4 EGO18371.1 - 6.2 6.9 23.1 37 4.4 16.0 2.0 1 1 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF3618 PF12277.3 EGO18371.1 - 8.4 6.5 21.0 6.4 6.9 1.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3618) APG6 PF04111.7 EGO18371.1 - 8.6 5.2 10.1 9.7 5.1 7.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HSP70 PF00012.15 EGO18371.1 - 9.2 4.0 7.3 9.2 4.0 5.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Rpn3_C PF08375.6 EGO18377.1 - 0.53 10.7 6.7 0.25 11.7 0.8 2.3 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Asp_protease_2 PF13650.1 EGO18381.1 - 1.3e-05 25.5 0.0 1.6e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO18381.1 - 8.9e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO18381.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EGO18382.1 - 7.1e-09 35.1 4.7 1.2e-08 34.4 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO18382.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO18382.1 - 0.02 14.6 2.9 0.02 14.6 2.0 2.0 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO18383.1 - 2.3e-08 33.9 0.2 2.3e-08 33.9 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein BMFP PF04380.8 EGO18383.1 - 0.036 14.1 0.9 15 5.7 0.2 3.3 3 0 0 3 3 3 0 Membrane fusogenic activity zf-CCHC PF00098.18 EGO18384.1 - 1.5e-08 34.1 4.0 2.7e-08 33.3 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO18384.1 - 2.2e-07 30.8 0.3 2.2e-07 30.8 0.2 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO18384.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO18384.1 - 0.8 9.4 8.3 0.074 12.7 1.9 2.1 2 0 0 2 2 2 0 Zinc knuckle Ring_hydroxyl_A PF00848.14 EGO18385.1 - 0.054 13.1 0.2 0.079 12.5 0.2 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) COesterase PF00135.23 EGO18390.1 - 8.1e-48 163.4 0.3 4.3e-38 131.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO18390.1 - 0.0017 17.9 0.0 0.0058 16.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4107 PF13389.1 EGO18390.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) CK_II_beta PF01214.13 EGO18392.1 - 0.007 15.8 0.2 0.007 15.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Retrotrans_gag PF03732.12 EGO18394.1 - 4.1e-08 33.1 0.0 7.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Zn_Tnp_IS1 PF03811.8 EGO18397.1 - 0.0069 15.8 3.3 0.018 14.5 0.1 2.3 2 0 0 2 2 2 1 InsA N-terminal domain zinc_ribbon_5 PF13719.1 EGO18397.1 - 1.7 8.3 4.1 8.6 6.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGO18397.1 - 4 7.2 5.4 9.4 6.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain UBN2_3 PF14244.1 EGO18400.1 - 0.042 13.4 0.0 0.091 12.3 0.0 1.6 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type MULE PF10551.4 EGO18401.1 - 0.00036 20.6 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.12 EGO18401.1 - 0.026 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase ubiquitin PF00240.18 EGO18402.1 - 0.049 13.0 0.1 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF1462 PF07315.6 EGO18402.1 - 0.067 13.1 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) NAD_binding_4 PF07993.7 EGO18403.1 - 8.5e-30 103.4 0.0 1.1e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO18403.1 - 5.3e-12 45.6 0.0 1.7e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGO18403.1 - 7.8e-09 35.6 0.1 2e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EGO18403.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO18403.1 - 0.029 13.0 0.0 0.15 10.7 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EGO18403.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EGO18403.1 - 0.24 10.2 0.0 0.43 9.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4011 PF13195.1 EGO18406.1 - 0.00044 20.3 1.5 0.00063 19.8 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) YL1 PF05764.8 EGO18406.1 - 0.016 14.7 13.4 0.024 14.2 9.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.7 EGO18406.1 - 0.031 13.9 9.8 0.048 13.3 6.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EGO18406.1 - 0.28 9.1 9.9 0.36 8.8 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 EGO18406.1 - 0.92 8.9 13.7 1.4 8.3 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EGO18407.1 - 0.036 13.9 2.5 0.092 12.7 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO18407.1 - 0.15 11.7 3.1 0.32 10.6 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO18409.1 - 1.8e-06 27.9 2.8 1.1e-05 25.4 2.0 2.3 1 1 0 1 1 1 1 Retrotransposon gag protein MFS_1 PF07690.11 EGO18411.1 - 2.7e-24 85.5 61.0 4.8e-16 58.4 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4219 PF13961.1 EGO18413.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 EGO18415.1 - 6e-11 41.8 0.2 9.9e-11 41.1 0.1 1.4 1 1 0 1 1 1 1 GAG-pre-integrase domain DUF3396 PF11876.3 EGO18420.1 - 0.059 12.4 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) DDE_Tnp_4 PF13359.1 EGO18422.1 - 5e-06 26.2 0.0 7.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FlbD PF06289.6 EGO18422.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein (FlbD) Rnf-Nqr PF02508.9 EGO18423.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein FAD_oxidored PF12831.2 EGO18424.1 - 1.7e-05 24.1 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO18424.1 - 6.4e-05 21.7 0.2 0.12 11.0 0.0 2.9 2 1 0 3 3 3 2 Tryptophan halogenase Abhydrolase_6 PF12697.2 EGO18424.1 - 0.035 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.19 EGO18424.1 - 0.076 11.9 0.1 5 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Gp_dh_N PF00044.19 EGO18424.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PB1-F2 PF11986.3 EGO18427.1 - 2 8.5 6.9 1.2 9.1 3.1 2.0 1 1 0 1 1 1 0 Influenza A Proapoptotic protein Pex14_N PF04695.8 EGO18428.1 - 1.5 8.8 5.4 1.5 8.8 0.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pap_E4 PF02711.9 EGO18428.1 - 8 7.3 11.7 15 6.4 1.3 2.4 1 1 1 2 2 2 0 E4 protein PI3K_1B_p101 PF10486.4 EGO18429.1 - 0.0048 14.5 0.6 0.0057 14.3 0.4 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2791 PF10923.3 EGO18430.1 - 0.01 14.4 0.5 0.016 13.8 0.3 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) CBFD_NFYB_HMF PF00808.18 EGO18434.1 - 4.1e-08 33.1 0.1 7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.8 EGO18434.1 - 0.0029 17.5 11.5 0.0037 17.2 8.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 EGO18434.1 - 0.11 11.4 12.8 0.15 11.0 8.9 1.3 1 0 0 1 1 1 0 BUD22 YqfQ PF14181.1 EGO18434.1 - 2.3 8.2 5.7 0.7 9.9 0.1 2.2 1 1 0 2 2 2 0 YqfQ-like protein DUF4219 PF13961.1 EGO18436.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) p450 PF00067.17 EGO18438.1 - 4.7e-70 236.4 0.0 5.8e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO18439.1 - 0.00011 20.8 0.0 0.00011 20.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO18440.1 - 2.3e-47 161.5 0.0 2.9e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EGO18441.1 - 0.048 12.6 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ELF PF03317.8 EGO18442.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 ELF protein ABC_membrane PF00664.18 EGO18443.1 - 1.1e-54 185.6 24.3 8.2e-28 97.5 4.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO18443.1 - 1.5e-49 167.8 0.0 4.1e-27 95.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO18443.1 - 5.7e-08 33.0 0.6 0.0082 16.1 0.1 3.7 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 EGO18443.1 - 1e-06 28.1 2.2 0.0016 17.6 0.9 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGO18443.1 - 6.1e-06 25.7 0.2 0.065 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGO18443.1 - 7e-06 26.5 1.7 0.049 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO18443.1 - 2.3e-05 24.4 0.0 0.038 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EGO18443.1 - 2.4e-05 24.7 0.5 0.094 13.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EGO18443.1 - 4.2e-05 22.9 2.1 0.095 12.2 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGO18443.1 - 4.4e-05 23.3 0.5 0.061 13.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EGO18443.1 - 0.00014 21.0 0.1 0.46 9.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EGO18443.1 - 0.00032 20.2 0.3 0.092 12.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EGO18443.1 - 0.00076 20.2 0.1 0.17 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO18443.1 - 0.0036 17.4 2.8 6.6 6.8 0.1 4.2 4 0 0 4 4 4 0 AAA domain UPF0079 PF02367.12 EGO18443.1 - 0.0058 16.2 1.3 0.14 11.7 0.0 3.1 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EGO18443.1 - 0.0067 15.8 0.3 0.53 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EGO18443.1 - 0.011 14.7 1.9 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EGO18443.1 - 0.027 14.3 1.3 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 EGO18443.1 - 0.055 12.0 2.0 2.3 6.7 0.1 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EGO18443.1 - 0.15 11.7 0.7 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EGO18443.1 - 0.17 11.4 3.1 13 5.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EGO18443.1 - 0.17 11.3 1.5 0.88 8.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EGO18443.1 - 0.18 12.1 0.1 21 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGO18443.1 - 0.19 11.5 2.0 0.67 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EGO18443.1 - 0.36 10.4 2.1 0.71 9.5 0.2 2.2 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 EGO18443.1 - 0.43 9.5 0.0 27 3.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EGO18443.1 - 0.44 10.0 3.3 38 3.6 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF2489 PF10675.4 EGO18444.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) CDC45 PF02724.9 EGO18453.1 - 0.11 10.4 13.2 0.15 10.0 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EGO18453.1 - 0.14 11.7 16.6 0.24 10.9 11.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EGO18453.1 - 0.23 10.4 14.5 0.43 9.6 10.0 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO18453.1 - 1.7 6.4 16.0 1.1 7.1 9.4 1.7 2 0 0 2 2 2 0 Nop14-like family Abhydrolase_3 PF07859.8 EGO18454.1 - 1.8e-14 53.8 0.0 3.1e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGO18454.1 - 1.5e-08 33.8 0.0 4.8e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EGO18454.1 - 1.2e-06 27.6 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EGO18454.1 - 2e-05 23.5 0.0 2.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.2 EGO18454.1 - 3.2e-05 23.7 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family RhoGEF PF00621.15 EGO18455.1 - 2.8e-06 27.3 0.0 2.9e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.15 EGO18456.1 - 7.3e-41 140.0 5.5 7.3e-41 140.0 3.8 2.2 3 0 0 3 3 3 1 Sulfate transporter family cNMP_binding PF00027.24 EGO18456.1 - 5.3e-13 48.6 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EGO18456.1 - 1.4e-09 37.3 0.1 3.4e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 STAS domain Fungal_trans PF04082.13 EGO18461.1 - 2.5e-17 62.6 3.4 3.8e-17 62.0 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.18 EGO18466.1 - 1.2e-38 133.2 4.6 1.7e-37 129.3 3.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO18466.1 - 1.1e-06 29.0 1.8 0.00056 20.3 0.6 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EGO18466.1 - 0.00055 19.5 0.0 0.0015 18.0 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGO18466.1 - 0.0029 17.3 0.3 0.81 9.5 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGO18466.1 - 0.014 15.3 0.7 3.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease TAXi_N PF14543.1 EGO18466.1 - 0.15 11.9 2.1 2.3 8.1 0.3 3.0 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Retrotrans_gag PF03732.12 EGO18468.1 - 1.2e-06 28.5 0.0 4.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF605 PF04652.11 EGO18469.1 - 0.58 9.5 7.2 0.69 9.2 5.0 1.1 1 0 0 1 1 1 0 Vta1 like Anillin PF08174.6 EGO18470.1 - 0.012 15.6 0.2 0.016 15.2 0.1 1.3 1 0 0 1 1 1 0 Cell division protein anillin DUF4219 PF13961.1 EGO18478.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Bac_chlorC PF02043.12 EGO18479.1 - 0.67 9.7 4.1 19 5.1 0.0 3.0 2 1 1 3 3 3 0 Bacteriochlorophyll C binding protein PepSY_TM_1 PF13172.1 EGO18480.1 - 4.8 7.0 7.3 0.85 9.4 1.8 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix PepSY_TM_1 PF13172.1 EGO18486.1 - 4.8 7.0 7.3 0.85 9.4 1.8 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix RVP_2 PF08284.6 EGO18487.1 - 0.037 13.9 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Adhesin_P1 PF03257.8 EGO18489.1 - 0.07 13.4 1.6 0.44 10.8 0.1 2.5 1 1 1 2 2 2 0 Mycoplasma adhesin P1 DUF4248 PF14053.1 EGO18493.1 - 0.057 13.0 0.1 0.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Dicty_REP PF05086.7 EGO18495.1 - 0.41 8.3 1.7 0.4 8.3 1.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EGO18495.1 - 0.74 9.5 19.6 0.99 9.1 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGO18495.1 - 1.2 8.9 14.0 2 8.2 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGO18495.1 - 8 4.2 15.4 11 3.9 10.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PIF1 PF05970.9 EGO18496.1 - 9.2e-09 34.7 0.0 1.1e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EGO18496.1 - 0.00066 19.3 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO18496.1 - 0.00092 18.8 0.0 0.00099 18.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO18496.1 - 0.003 17.0 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EGO18496.1 - 0.0071 15.8 0.1 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EGO18496.1 - 0.014 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EGO18496.1 - 0.049 13.7 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EGO18496.1 - 0.054 13.3 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.7 EGO18496.1 - 0.069 12.2 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EGO18496.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EGO18496.1 - 0.15 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Alpha_kinase PF02816.13 EGO18497.1 - 4.4e-17 62.3 0.0 5.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.11 EGO18498.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Abhydrolase_6 PF12697.2 EGO18503.1 - 7.3e-16 58.7 0.3 1e-15 58.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO18503.1 - 1.2e-11 44.5 0.3 4.5e-11 42.6 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGO18503.1 - 1.3e-10 41.1 0.4 2.1e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EGO18503.1 - 3.2e-07 30.0 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EGO18503.1 - 5.8e-05 22.4 0.0 0.018 14.2 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family PHB_depo_C PF06850.6 EGO18503.1 - 0.0061 15.8 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 PHB de-polymerase C-terminus Abhydrolase_1 PF00561.15 EGO18503.1 - 0.019 14.4 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold AA_permease_2 PF13520.1 EGO18504.1 - 3.9e-61 206.8 58.9 4.9e-61 206.5 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO18504.1 - 4.6e-12 45.0 50.8 6.5e-12 44.5 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1129 PF06570.6 EGO18504.1 - 5.1 6.3 6.2 15 4.8 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) UbiA PF01040.13 EGO18508.1 - 3.8e-29 101.6 20.5 4.6e-29 101.4 14.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1129 PF06570.6 EGO18508.1 - 0.46 9.7 3.6 0.47 9.7 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Ferric_reduct PF01794.14 EGO18508.1 - 0.51 10.4 9.5 54 3.8 6.6 2.7 1 1 0 1 1 1 0 Ferric reductase like transmembrane component FAD_binding_3 PF01494.14 EGO18509.1 - 1.8e-65 221.3 0.0 2.4e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO18509.1 - 1.5e-05 24.0 0.0 0.00013 21.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO18509.1 - 7.2e-05 23.1 0.3 0.0014 18.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO18509.1 - 0.00015 21.6 0.0 0.00074 19.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO18509.1 - 0.00022 19.9 0.0 0.00043 19.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EGO18509.1 - 0.00038 20.4 0.1 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO18509.1 - 0.012 15.3 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGO18509.1 - 0.021 13.7 0.1 0.11 11.4 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EGO18509.1 - 0.021 13.2 0.1 0.16 10.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EGO18509.1 - 0.072 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EGO18509.1 - 0.09 12.8 0.0 0.24 11.4 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EGO18510.1 - 4.6e-49 167.0 47.5 2.2e-47 161.5 32.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 EGO18511.1 - 2.9e-25 89.1 0.0 4.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO18511.1 - 0.00012 21.8 0.0 0.00034 20.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DXP_reductoisom PF02670.11 EGO18511.1 - 0.0017 18.8 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 EGO18511.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EGO18512.1 - 2.8e-73 247.0 0.0 8.7e-72 242.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO18512.1 - 5.3e-18 65.2 0.0 9.6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EGO18512.1 - 3.5e-06 25.7 0.1 5.9e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EGO18512.1 - 5.2e-06 25.7 0.1 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGO18512.1 - 1.2e-05 24.4 0.2 2.6e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO18512.1 - 3.4e-05 22.8 0.4 5.3e-05 22.2 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO18512.1 - 0.00014 21.8 0.0 0.00035 20.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO18512.1 - 0.00015 20.9 0.4 0.00028 20.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO18512.1 - 0.00034 19.6 0.3 0.00057 18.8 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EGO18512.1 - 0.00046 20.5 0.1 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO18512.1 - 0.00062 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO18512.1 - 0.00089 19.3 0.1 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO18512.1 - 0.00089 18.2 0.3 0.002 17.0 0.2 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGO18512.1 - 0.046 13.5 0.1 0.079 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EGO18512.1 - 0.12 10.9 0.0 0.24 9.9 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Alpha_kinase PF02816.13 EGO18513.1 - 1.1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.11 EGO18515.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Transposase_21 PF02992.9 EGO18520.1 - 5.1e-13 48.6 0.1 8.4e-13 47.9 0.0 1.5 1 1 0 1 1 1 1 Transposase family tnp2 Retrotrans_gag PF03732.12 EGO18522.1 - 6.5e-06 26.1 1.6 3.8e-05 23.6 1.1 2.3 1 1 0 1 1 1 1 Retrotransposon gag protein Alpha-amylase PF00128.19 EGO18524.1 - 2.4e-21 76.4 12.1 2.3e-20 73.2 2.2 3.5 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EGO18524.1 - 2.9e-16 59.7 0.1 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EGO18524.1 - 3.6e-08 33.6 0.0 9.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGO18524.1 - 8.5e-08 31.8 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Histone PF00125.19 EGO18525.1 - 1.4e-21 76.3 0.2 2e-21 75.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO18525.1 - 2.8e-05 24.0 0.1 5.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGO18525.1 - 0.00028 21.1 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EGO18525.1 - 0.0081 16.6 0.4 0.011 16.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1018) RP-C PF03428.8 EGO18525.1 - 0.048 13.1 0.1 0.077 12.4 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF3408 PF11888.3 EGO18525.1 - 0.52 10.2 3.5 0.89 9.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PepSY_TM_1 PF13172.1 EGO18532.1 - 0.56 10.0 3.1 1.2 8.9 2.1 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO18533.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO18533.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO18533.1 - 0.13 11.9 0.5 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Chromo PF00385.19 EGO18538.1 - 2.1e-06 27.2 0.1 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EGO18538.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain RVP_2 PF08284.6 EGO18539.1 - 0.035 14.0 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Cys_rich_VLP PF14194.1 EGO18541.1 - 0.018 14.7 0.8 0.033 13.9 0.6 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP zf-RING_3 PF14369.1 EGO18541.1 - 0.15 12.0 4.3 0.26 11.3 1.8 2.1 1 1 1 2 2 2 0 zinc-finger DUF4219 PF13961.1 EGO18544.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Myb_DNA-bind_3 PF12776.2 EGO18548.1 - 0.0044 17.6 0.0 0.0087 16.6 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain hNIFK_binding PF12196.3 EGO18549.1 - 0.056 12.8 0.1 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK WD40 PF00400.27 EGO18553.1 - 1.1e-57 189.9 21.6 7.5e-11 41.4 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EGO18553.1 - 3.3e-32 111.5 0.0 1.4e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 EGO18553.1 - 0.00011 21.8 0.0 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 LisH Nup160 PF11715.3 EGO18553.1 - 0.0002 19.6 3.0 3.4 5.6 0.1 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EGO18553.1 - 0.023 14.3 0.0 3.8 7.1 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PAP2 PF01569.16 EGO18554.1 - 2.5e-10 40.0 5.0 3.2e-10 39.7 3.5 1.2 1 0 0 1 1 1 1 PAP2 superfamily DUF2418 PF10332.4 EGO18555.1 - 2.5e-21 75.8 0.0 5.2e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) IL32 PF15225.1 EGO18555.1 - 0.096 12.6 0.5 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Interleukin 32 zf-C2H2 PF00096.21 EGO18556.1 - 1.1e-12 47.4 11.4 5.6e-07 29.5 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO18556.1 - 3.1e-11 42.7 9.2 1e-05 25.4 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO18556.1 - 4.7e-11 42.4 18.5 9.3e-09 35.1 1.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGO18556.1 - 1.4e-06 28.2 0.8 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGO18556.1 - 1.9e-05 24.3 1.4 0.0059 16.4 0.0 2.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EGO18556.1 - 0.0002 21.4 0.9 0.024 14.8 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-CGNR PF11706.3 EGO18556.1 - 0.0067 15.9 3.2 0.81 9.2 0.4 2.3 2 0 0 2 2 2 2 CGNR zinc finger zf-C2HC_2 PF13913.1 EGO18556.1 - 0.036 13.7 0.2 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-LYAR PF08790.6 EGO18556.1 - 0.039 13.6 0.2 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Ogr_Delta PF04606.7 EGO18556.1 - 0.057 13.0 3.5 0.063 12.9 0.3 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger Toxin_8 PF07365.7 EGO18556.1 - 0.07 13.0 5.0 1 9.3 0.7 2.2 2 0 0 2 2 2 0 Alpha conotoxin precursor FANCL_C PF11793.3 EGO18556.1 - 0.18 11.7 2.0 0.65 9.9 0.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain CHORD PF04968.7 EGO18556.1 - 0.58 10.4 5.8 3.8 7.8 0.5 2.1 1 1 1 2 2 2 0 CHORD Notch PF00066.12 EGO18556.1 - 1 9.7 5.5 5.5 7.3 0.6 2.1 2 0 0 2 2 2 0 LNR domain zf-BED PF02892.10 EGO18556.1 - 3.4 7.4 5.9 1.5 8.6 0.4 2.2 2 1 0 2 2 2 0 BED zinc finger FBPase PF00316.15 EGO18557.1 - 3.8e-129 430.1 0.0 4.3e-129 429.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EGO18557.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Pmp3 PF01679.12 EGO18558.1 - 9e-15 54.1 2.2 1.2e-14 53.7 1.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator rve_3 PF13683.1 EGO18558.1 - 0.039 13.4 0.5 0.039 13.4 0.4 2.1 2 1 1 3 3 3 0 Integrase core domain NapE PF06796.6 EGO18558.1 - 0.056 12.7 0.0 0.056 12.7 0.0 1.7 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE PNGaseA PF12222.3 EGO18559.1 - 1.2e-82 278.0 9.4 1.8e-82 277.5 6.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Raptor_N PF14538.1 EGO18559.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain HTH_45 PF14947.1 EGO18559.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix ACP PF06857.6 EGO18559.1 - 0.16 11.8 0.2 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) FTHFS PF01268.14 EGO18560.1 - 5.5e-256 849.9 0.3 7.8e-256 849.4 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EGO18560.1 - 5.7e-65 217.2 0.8 5.7e-65 217.2 0.5 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGO18560.1 - 1.1e-34 118.9 0.2 2.5e-34 117.7 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain tRNA-synt_2d PF01409.15 EGO18561.1 - 3.9e-44 150.7 0.1 4.6e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EGO18561.1 - 2.1e-23 82.3 0.0 4.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain zf-UDP PF14569.1 EGO18561.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger ETC_C1_NDUFA5 PF04716.9 EGO18562.1 - 5.1e-19 67.5 0.0 8.7e-19 66.7 0.0 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF4201 PF13870.1 EGO18564.1 - 2.2 7.6 7.3 3 7.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) MutS_II PF05188.12 EGO18565.1 - 0.012 15.7 0.1 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 MutS domain II Peptidase_M41 PF01434.13 EGO18566.1 - 3.7e-72 242.2 0.5 5.9e-72 241.5 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGO18566.1 - 1.2e-41 142.0 0.0 2.3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO18566.1 - 1.7e-05 25.6 0.0 5.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO18566.1 - 5e-05 22.4 0.0 0.00016 20.8 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGO18566.1 - 6.5e-05 21.8 0.1 0.00014 20.6 0.1 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EGO18566.1 - 8.3e-05 22.3 0.0 0.00034 20.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO18566.1 - 0.00014 21.9 0.3 0.0076 16.3 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO18566.1 - 0.0002 21.0 0.4 0.00082 19.0 0.3 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGO18566.1 - 0.00049 20.1 4.2 0.0074 16.2 0.1 3.3 2 2 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EGO18566.1 - 0.00053 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EGO18566.1 - 0.0016 18.4 0.0 0.0046 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EGO18566.1 - 0.0026 17.1 3.5 0.027 13.8 0.4 2.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EGO18566.1 - 0.003 16.7 0.5 0.0071 15.5 0.4 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGO18566.1 - 0.0054 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO18566.1 - 0.0055 15.8 0.1 0.013 14.6 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EGO18566.1 - 0.0057 16.5 0.0 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO18566.1 - 0.008 16.1 0.0 0.026 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EGO18566.1 - 0.01 15.4 0.1 0.071 12.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EGO18566.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGO18566.1 - 0.047 12.6 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EGO18566.1 - 0.079 13.0 0.1 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGO18566.1 - 0.1 11.4 0.1 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 EGO18566.1 - 0.13 11.4 0.0 0.44 9.7 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_M50B PF13398.1 EGO18566.1 - 0.24 10.7 0.3 0.53 9.6 0.1 1.6 2 0 0 2 2 2 0 Peptidase M50B-like DUF1227 PF06777.6 EGO18567.1 - 2.6e-59 199.1 0.3 3.4e-59 198.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGO18567.1 - 2.8e-15 56.1 0.2 5.5e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 SNF2_N PF00176.18 EGO18567.1 - 0.023 13.4 0.1 0.044 12.5 0.1 1.5 1 1 0 1 1 1 0 SNF2 family N-terminal domain YtxC PF08812.6 EGO18567.1 - 0.026 14.0 0.4 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 YtxC-like family DUF2058 PF09831.4 EGO18567.1 - 0.072 12.9 0.3 0.16 11.8 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DEAD_2 PF06733.10 EGO18568.1 - 1.1e-16 60.6 1.3 1.3e-16 60.4 0.9 1.1 1 0 0 1 1 1 1 DEAD_2 Cellulase PF00150.13 EGO18569.1 - 9.2e-17 61.1 1.4 3.6e-16 59.2 1.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGO18569.1 - 8.4e-07 29.3 0.0 2.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EGO18569.1 - 0.00029 20.0 2.0 0.38 9.8 0.0 3.0 3 0 0 3 3 3 2 Beta-galactosidase Glyco_hydro_2_C PF02836.12 EGO18569.1 - 0.045 12.6 0.1 0.093 11.6 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain TPR_12 PF13424.1 EGO18570.1 - 9e-07 28.7 2.0 0.16 11.9 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO18570.1 - 0.003 17.3 4.4 0.46 10.5 0.0 4.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO18570.1 - 0.022 14.6 1.2 0.42 10.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO18570.1 - 0.039 13.5 0.2 3 7.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 EGO18570.1 - 0.083 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.1 EGO18570.1 - 0.093 12.5 1.3 12 5.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M49 PF03571.10 EGO18571.1 - 1.2e-193 644.1 0.0 1.6e-193 643.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 JmjN PF02375.12 EGO18571.1 - 0.066 12.7 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 jmjN domain SpoIIE PF07228.7 EGO18572.1 - 1.7e-13 50.6 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGO18572.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EGO18572.1 - 0.018 14.4 0.1 1 8.6 0.0 2.2 1 1 1 2 2 2 0 Protein phosphatase 2C Abhydrolase_6 PF12697.2 EGO18573.1 - 2.8e-26 92.8 0.0 3.6e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO18573.1 - 2e-12 47.1 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO18573.1 - 1.8e-10 40.7 0.0 3.4e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO18573.1 - 4.8e-06 26.3 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 EGO18573.1 - 5.1e-05 21.9 0.0 0.011 14.2 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Ndr PF03096.9 EGO18573.1 - 0.069 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.6 EGO18573.1 - 0.13 11.0 0.1 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase F-box-like PF12937.2 EGO18574.1 - 0.00034 20.2 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like ORC6 PF05460.8 EGO18574.1 - 0.0022 17.1 1.5 0.0022 17.1 1.1 1.5 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) F-box-like PF12937.2 EGO18575.1 - 0.0016 18.1 0.0 0.0093 15.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like FAM101 PF15068.1 EGO18575.1 - 0.027 13.9 0.4 0.043 13.2 0.3 1.2 1 0 0 1 1 1 0 FAM101 family Glucan_synthase PF02364.10 EGO18577.1 - 0 1378.6 0.1 0 1377.9 0.1 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGO18577.1 - 2e-38 130.8 0.2 5.7e-38 129.4 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RAI16-like PF10257.4 EGO18578.1 - 9.4e-71 238.5 0.4 1.7e-70 237.7 0.3 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CENP-B_dimeris PF09026.5 EGO18578.1 - 3.9 7.7 9.2 3 8.1 2.9 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DnaJ PF00226.26 EGO18579.1 - 1e-18 66.8 1.7 1e-18 66.8 1.2 2.4 3 0 0 3 3 3 1 DnaJ domain TrmB PF01978.14 EGO18579.1 - 1.4 8.6 3.8 10 5.9 0.1 3.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Aldo_ket_red PF00248.16 EGO18580.1 - 4.6e-50 170.0 0.0 5.2e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PPK2 PF03976.9 EGO18580.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) zf-primase PF09329.6 EGO18580.1 - 0.37 10.4 1.5 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 Primase zinc finger Mak10 PF04112.8 EGO18581.1 - 0.04 13.1 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF202 PF02656.10 EGO18581.1 - 2.3 8.4 16.1 0.58 10.4 0.5 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF202) SET PF00856.23 EGO18582.1 - 5.9e-05 23.4 0.3 0.00018 21.8 0.2 1.9 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EGO18582.1 - 0.0001 22.1 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Peptidase_S64 PF08192.6 EGO18583.1 - 0.083 11.2 0.2 0.35 9.1 0.1 1.8 2 0 0 2 2 2 0 Peptidase family S64 Peptidase_S32 PF05579.8 EGO18583.1 - 0.1 11.5 0.3 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Pico_P2A PF00947.14 EGO18583.1 - 0.14 11.9 0.1 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Picornavirus core protein 2A adh_short PF00106.20 EGO18584.1 - 1.4e-31 109.6 5.0 1.9e-31 109.2 3.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO18584.1 - 8.6e-15 54.8 2.3 1.2e-14 54.4 1.6 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO18584.1 - 2.7e-13 50.2 0.5 3.3e-13 49.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EGO18584.1 - 1.2e-05 25.0 1.0 3.1e-05 23.6 0.7 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EGO18584.1 - 0.00065 18.9 0.0 0.0008 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGO18584.1 - 0.02 14.3 0.4 0.028 13.8 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO18584.1 - 0.59 10.1 4.1 7.4 6.5 2.9 2.4 1 1 0 1 1 1 0 NADH(P)-binding DUF904 PF06005.7 EGO18586.1 - 0.046 14.0 1.2 0.066 13.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3972 PF13118.1 EGO18586.1 - 0.058 13.4 0.5 0.07 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Vps51 PF08700.6 EGO18586.1 - 0.08 12.7 1.1 0.11 12.3 0.8 1.3 1 0 0 1 1 1 0 Vps51/Vps67 Imm5 PF14423.1 EGO18586.1 - 0.086 12.4 0.1 0.1 12.2 0.1 1.0 1 0 0 1 1 1 0 Immunity protein Imm5 GOLGA2L5 PF15070.1 EGO18586.1 - 0.16 10.4 2.5 0.18 10.2 1.7 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 IncA PF04156.9 EGO18586.1 - 0.31 10.5 2.3 0.32 10.5 1.6 1.0 1 0 0 1 1 1 0 IncA protein Abhydrolase_6 PF12697.2 EGO18587.1 - 3.9e-12 46.5 1.0 5.3e-12 46.0 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO18587.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_S21 PF01165.15 EGO18589.1 - 5.9e-10 38.4 7.6 1e-09 37.6 5.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 DUF3708 PF12501.3 EGO18589.1 - 0.081 12.7 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Cyclin_N PF00134.18 EGO18591.1 - 4.1e-15 55.4 0.1 9e-15 54.3 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO18591.1 - 1.5e-05 24.9 0.5 0.077 12.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EGO18591.1 - 3e-05 23.7 0.0 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat IF-2B PF01008.12 EGO18594.1 - 7e-60 202.4 0.0 1.7e-59 201.1 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family HisKA PF00512.20 EGO18594.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Peptidase_M24 PF00557.19 EGO18597.1 - 1.3e-45 155.5 0.1 1.6e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Acyltransferase PF01553.16 EGO18598.1 - 3.5e-06 26.4 0.0 7.2e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 Acyltransferase CLASP_N PF12348.3 EGO18599.1 - 1.3e-30 106.4 0.0 5.4e-10 39.0 0.0 5.4 5 0 0 5 5 5 4 CLASP N terminal HEAT_2 PF13646.1 EGO18599.1 - 5.6e-12 45.7 17.1 0.0092 16.2 0.0 9.3 7 3 2 9 9 9 4 HEAT repeats HEAT PF02985.17 EGO18599.1 - 2.9e-11 42.4 13.9 0.12 12.4 0.0 11.7 13 0 0 13 13 13 4 HEAT repeat HEAT_EZ PF13513.1 EGO18599.1 - 0.00068 20.0 19.0 6.4 7.3 0.0 9.1 9 1 1 10 10 10 2 HEAT-like repeat VHS PF00790.14 EGO18599.1 - 0.086 12.4 0.1 20 4.7 0.0 3.8 4 0 0 4 4 4 0 VHS domain Cnd1 PF12717.2 EGO18599.1 - 0.11 12.3 1.1 4.8 7.0 0.0 4.2 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 BCAS2 PF05700.6 EGO18599.1 - 0.18 11.2 0.0 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) NOC3p PF07540.6 EGO18600.1 - 1.8e-26 92.2 0.2 1.3e-25 89.4 0.0 2.6 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EGO18600.1 - 2.4e-22 79.1 0.0 8.2e-22 77.3 0.0 2.0 1 0 0 1 1 1 1 CBF/Mak21 family DUF1843 PF08898.5 EGO18600.1 - 0.23 11.5 2.9 0.56 10.2 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) TEA PF01285.13 EGO18601.1 - 1.2e-10 41.1 0.3 1.2e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family MSC PF09402.5 EGO18602.1 - 8.7e-56 189.0 0.0 1.2e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EGO18602.1 - 1e-12 47.3 0.0 2.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Pyr_redox_2 PF07992.9 EGO18603.1 - 8.4e-05 22.5 1.0 0.0027 17.5 0.7 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EGO18603.1 - 0.026 14.0 0.6 0.039 13.4 0.4 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.1 EGO18603.1 - 0.069 12.9 0.1 4.5 7.0 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding PepSY_TM_1 PF13172.1 EGO18604.1 - 1.4 8.7 4.1 3 7.7 2.8 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Pyr_redox_2 PF07992.9 EGO18605.1 - 2.6e-06 27.4 0.0 4.6e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO18605.1 - 0.022 14.5 0.0 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Malic_M PF03949.10 EGO18605.1 - 0.074 12.5 0.7 0.11 12.0 0.5 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Kelch_1 PF01344.20 EGO18605.1 - 1.7 8.2 4.2 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Kelch motif MraY_sig1 PF10555.4 EGO18607.1 - 0.71 9.3 3.5 3.9 7.0 0.2 2.7 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Cu_bind_like PF02298.12 EGO18608.1 - 4.3e-06 26.4 0.3 9.1e-06 25.3 0.2 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 EGO18608.1 - 0.00032 20.8 0.4 0.00096 19.3 0.3 1.8 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF4477 PF14780.1 EGO18610.1 - 2.6e-05 23.6 0.1 0.05 12.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) Adaptin_N PF01602.15 EGO18611.1 - 1.1e-131 439.7 6.2 1.3e-131 439.4 4.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGO18611.1 - 3.6e-25 88.8 0.8 2.3e-23 82.9 0.0 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGO18611.1 - 4.8e-13 49.1 9.5 3.4e-08 33.6 0.2 5.4 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 EGO18611.1 - 1.7e-09 36.9 3.8 0.013 15.4 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EGO18611.1 - 1.3e-05 25.5 1.0 0.86 10.1 0.0 5.9 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 EGO18611.1 - 0.00013 21.6 1.1 0.86 9.5 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EGO18611.1 - 0.028 13.7 0.1 0.34 10.2 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.4 EGO18611.1 - 0.04 13.6 0.1 5.7 6.7 0.0 3.3 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain OTU PF02338.14 EGO18612.1 - 4.9e-15 56.1 0.0 2.1e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGO18612.1 - 3e-06 26.7 0.0 0.00086 18.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain eIF3_subunit PF08597.5 EGO18612.1 - 0.015 14.8 1.1 0.018 14.5 0.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Aldo_ket_red PF00248.16 EGO18613.1 - 1.3e-48 165.2 0.0 1.5e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bromo_TP PF07524.8 EGO18613.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated ECH PF00378.15 EGO18615.1 - 1.2e-23 83.4 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Cupin_2 PF07883.6 EGO18616.1 - 2.4e-08 33.3 0.6 4.9e-08 32.3 0.4 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGO18616.1 - 0.00071 19.2 0.5 0.0018 17.9 0.1 1.8 2 1 1 3 3 3 1 AraC-like ligand binding domain PP1_inhibitor PF05361.7 EGO18617.1 - 0.053 13.2 1.3 0.056 13.1 0.9 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor RRM_1 PF00076.17 EGO18620.1 - 7.2e-25 86.4 0.0 2.2e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EGO18620.1 - 3e-19 67.3 0.0 0.00014 21.1 0.0 5.4 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 EGO18620.1 - 1e-16 60.6 0.0 4.8e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO18620.1 - 1.2e-12 47.4 0.0 1.1e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3505 PF12013.3 EGO18620.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Adeno_PIX PF03955.9 EGO18621.1 - 1.8 9.1 6.2 2.2 8.8 0.2 2.3 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) CLTH PF10607.4 EGO18622.1 - 4.5e-21 75.0 0.0 1.8e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGO18622.1 - 2.3e-17 62.4 1.0 5.6e-17 61.1 0.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EGO18622.1 - 0.0019 17.4 1.2 0.0022 17.2 0.0 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EGO18622.1 - 0.0022 17.7 0.2 0.0043 16.8 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGO18622.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 EGO18622.1 - 0.015 14.7 1.6 0.038 13.5 1.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EGO18622.1 - 0.021 14.8 0.6 0.041 13.9 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 EGO18622.1 - 0.046 14.0 0.4 1.8 9.0 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C3HC4 PF00097.20 EGO18622.1 - 0.18 11.5 0.8 0.34 10.5 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pirin PF02678.11 EGO18623.1 - 3e-30 104.2 0.5 4.9e-30 103.5 0.1 1.5 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EGO18623.1 - 2.8e-23 81.9 0.0 1.2e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGO18623.1 - 0.033 13.6 0.9 0.16 11.4 0.4 2.2 2 0 0 2 2 2 0 Cupin domain TSP_C PF05735.7 EGO18623.1 - 0.033 13.7 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Thrombospondin C-terminal region AA_permease PF00324.16 EGO18624.1 - 4.1e-117 391.4 41.4 5e-117 391.1 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO18624.1 - 8.8e-29 100.2 46.5 1.2e-28 99.8 32.3 1.2 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.18 EGO18625.1 - 3e-66 223.2 0.0 4.8e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EGO18625.1 - 4.2e-38 131.1 12.9 7.5e-38 130.2 8.9 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EGO18625.1 - 4.2e-13 48.9 0.0 8.7e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO18625.1 - 3.8e-08 32.4 0.6 1.1e-07 30.9 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EGO18625.1 - 0.11 12.6 0.1 0.84 9.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain U1snRNP70_N PF12220.3 EGO18625.1 - 7.3 6.9 10.5 0.14 12.5 1.3 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal K_oxygenase PF13434.1 EGO18626.1 - 6.4e-93 311.3 0.0 9e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO18626.1 - 1.9e-08 34.2 0.2 7.5e-07 29.0 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGO18626.1 - 9.5e-08 32.3 0.0 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO18626.1 - 8.4e-05 22.5 0.0 0.0018 18.1 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO18626.1 - 0.00021 21.6 0.0 0.093 13.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 EGO18627.1 - 1.4e-92 310.2 0.0 2.5e-92 309.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGO18627.1 - 5.1e-90 301.3 0.2 8.2e-31 106.9 0.0 4.1 4 0 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EGO18627.1 - 3.8e-28 97.5 3.4 4.4e-08 33.2 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.8 EGO18627.1 - 0.00055 18.5 0.0 0.24 9.8 0.0 2.2 2 0 0 2 2 2 2 GH3 auxin-responsive promoter AMP-binding_C PF13193.1 EGO18627.1 - 0.0017 19.2 0.3 0.009 16.9 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PTEN_C2 PF10409.4 EGO18627.1 - 0.0049 16.5 0.1 0.73 9.5 0.1 2.4 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein WES_acyltransf PF03007.11 EGO18627.1 - 0.019 14.5 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 EGO18627.1 - 0.03 12.8 0.0 4.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Alcohol acetyltransferase SH2_2 PF14633.1 EGO18628.1 - 3.8e-67 225.5 0.6 3.8e-67 225.5 0.4 2.1 3 0 0 3 3 3 1 SH2 domain YqgF PF14639.1 EGO18628.1 - 1e-29 103.0 0.1 1.1e-15 57.5 0.0 2.8 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EGO18628.1 - 1.1e-29 102.8 2.2 1.1e-29 102.8 1.6 3.1 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EGO18628.1 - 9.8e-29 99.5 0.0 1.9e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EGO18628.1 - 1.6e-20 73.0 31.4 1.6e-20 73.0 21.8 6.1 6 1 1 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EGO18628.1 - 3e-16 59.4 0.8 8.3e-16 58.0 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EGO18628.1 - 3.7e-08 33.0 0.0 8.7e-06 25.4 0.0 2.8 2 0 0 2 2 2 1 SH2 domain S1 PF00575.18 EGO18628.1 - 0.00059 19.8 3.7 0.011 15.8 1.9 2.6 2 0 0 2 2 2 1 S1 RNA binding domain B12-binding PF02310.14 EGO18628.1 - 0.057 13.2 0.0 0.21 11.4 0.0 2.0 1 1 0 1 1 1 0 B12 binding domain SRP54 PF00448.17 EGO18629.1 - 4.5e-72 241.6 0.6 8.1e-72 240.7 0.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGO18629.1 - 8.4e-22 77.3 0.3 8.4e-22 77.3 0.2 4.5 3 2 3 6 6 5 1 Signal peptide binding domain SRP54_N PF02881.14 EGO18629.1 - 1.5e-15 56.9 4.7 3.2e-15 55.9 3.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EGO18629.1 - 7.7e-06 25.8 0.1 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EGO18629.1 - 9.6e-06 25.1 0.1 2.2e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EGO18629.1 - 0.00084 19.0 0.1 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EGO18629.1 - 0.0029 17.0 0.3 0.017 14.5 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1768 PF08719.6 EGO18629.1 - 0.043 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) AAA_17 PF13207.1 EGO18629.1 - 0.098 13.4 0.0 0.22 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO18629.1 - 0.12 12.5 0.1 0.56 10.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.1 EGO18629.1 - 0.15 11.9 0.0 23 4.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2201 PF09967.4 EGO18629.1 - 0.28 11.2 1.4 1.4 8.9 0.1 2.7 2 1 0 2 2 2 0 VWA-like domain (DUF2201) WD40 PF00400.27 EGO18630.1 - 8.7e-12 44.4 13.2 0.0037 17.0 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Methyltransf_23 PF13489.1 EGO18631.1 - 1.1e-05 25.1 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO18631.1 - 7e-05 23.3 0.1 0.00013 22.5 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO18631.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO18631.1 - 0.0025 16.9 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGO18631.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO18631.1 - 0.0078 16.2 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EGO18631.1 - 0.025 15.0 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO18631.1 - 0.025 15.0 0.0 0.067 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGO18631.1 - 0.028 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EGO18631.1 - 0.066 12.3 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EGO18631.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 EGO18631.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SCAMP PF04144.8 EGO18632.1 - 1.2e-48 165.3 3.8 1.4e-48 165.1 2.6 1.0 1 0 0 1 1 1 1 SCAMP family Unstab_antitox PF09720.5 EGO18632.1 - 0.079 12.6 0.5 0.16 11.7 0.4 1.5 1 0 0 1 1 1 0 Putative addiction module component MFS_1 PF07690.11 EGO18634.1 - 3e-37 128.1 30.4 1.6e-36 125.7 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L30_N PF08079.7 EGO18635.1 - 3.7e-25 87.7 15.5 6.8e-25 86.8 10.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGO18635.1 - 4.7e-20 70.9 1.6 1.2e-19 69.6 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PNTB PF02233.11 EGO18636.1 - 3e-172 573.5 24.0 3e-172 573.5 16.6 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EGO18636.1 - 1.5e-49 167.8 0.4 3.3e-49 166.6 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EGO18636.1 - 8.5e-46 155.3 0.4 2.9e-45 153.6 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EGO18636.1 - 3.6e-32 110.3 4.5 3.6e-32 110.3 3.1 4.8 3 2 0 4 4 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EGO18636.1 - 0.00029 20.0 1.0 0.77 8.8 0.1 3.9 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EGO18636.1 - 0.037 12.8 0.6 0.061 12.1 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EGO18636.1 - 0.043 13.7 0.7 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO18636.1 - 3.3 7.8 8.7 0.93 9.5 1.5 3.4 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ADK PF00406.17 EGO18637.1 - 1.4e-10 41.2 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EGO18637.1 - 2.4e-05 25.1 0.0 3.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO18637.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO18637.1 - 0.0055 15.8 0.0 0.0077 15.3 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 EGO18637.1 - 0.0059 16.2 0.0 0.0069 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO18637.1 - 0.0064 16.3 0.0 0.0095 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain NAD_binding_10 PF13460.1 EGO18638.1 - 1.2e-11 44.9 0.0 7.2e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO18638.1 - 1.9e-09 37.2 0.0 4.2e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO18638.1 - 4.7e-05 22.2 0.0 0.0008 18.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGO18638.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGO18638.1 - 0.099 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF2665 PF11654.3 EGO18639.1 - 6.1e-15 54.5 0.0 7.5e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) NatB_MDM20 PF09797.4 EGO18640.1 - 3.1e-69 233.4 2.2 5.3e-69 232.6 1.5 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 EGO18640.1 - 0.00018 21.8 0.0 0.7 10.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 EGO18640.1 - 0.0046 17.2 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_19 PF14559.1 EGO18640.1 - 0.021 15.1 0.1 0.16 12.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4473 PF14747.1 EGO18640.1 - 0.14 12.4 4.8 0.5 10.6 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4473) Gaa1 PF04114.9 EGO18641.1 - 5.7e-62 210.0 18.3 5.4e-34 117.7 0.0 3.1 2 1 1 3 3 3 2 Gaa1-like, GPI transamidase component Med16 PF11635.3 EGO18642.1 - 3.5e-07 28.6 1.0 4e-06 25.1 0.7 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 ATG_C PF09333.6 EGO18643.1 - 1.1e-32 112.0 0.1 4.2e-32 110.2 0.0 2.1 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EGO18643.1 - 1.6e-09 37.3 0.0 4.6e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 EGO18643.1 - 0.0017 17.9 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Ribosomal_L29 PF00831.18 EGO18643.1 - 0.17 11.5 0.6 0.42 10.3 0.4 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein RPA_C PF08784.6 EGO18644.1 - 2.2e-14 53.7 0.0 4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EGO18644.1 - 8.9e-09 35.0 0.1 1.6e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EGO18644.1 - 0.12 12.2 0.2 0.3 10.9 0.0 1.8 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain LURAP PF14854.1 EGO18644.1 - 0.17 11.5 0.7 0.82 9.3 0.2 2.0 2 0 0 2 2 2 0 Leucine rich adaptor protein Snf7 PF03357.16 EGO18645.1 - 3.2e-17 62.4 4.5 4.9e-17 61.8 3.1 1.2 1 0 0 1 1 1 1 Snf7 MutS_III PF05192.13 EGO18645.1 - 0.033 13.9 0.3 0.94 9.2 0.0 2.9 2 1 0 2 2 2 0 MutS domain III HAUS-augmin3 PF14932.1 EGO18645.1 - 0.4 9.8 3.9 0.44 9.6 1.3 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin-6_N PF09177.6 EGO18645.1 - 2 8.8 5.7 0.71 10.3 0.3 2.7 2 1 0 3 3 3 0 Syntaxin 6, N-terminal PQ-loop PF04193.9 EGO18646.1 - 4e-39 131.9 9.1 7.3e-19 67.0 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EGO18646.1 - 0.0035 17.1 1.8 0.0035 17.1 1.2 1.9 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF2069 PF09842.4 EGO18646.1 - 0.12 12.2 0.9 0.26 11.2 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF1378 PF07125.6 EGO18646.1 - 1.8 8.5 4.2 14 5.7 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1378) DHDPS PF00701.17 EGO18648.1 - 8.3e-31 106.6 0.0 4.7e-30 104.1 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family CLTH PF10607.4 EGO18650.1 - 1.2e-17 63.9 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGO18650.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 LisH DUF4537 PF15057.1 EGO18652.1 - 5.4e-09 35.8 0.1 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) BRCT PF00533.21 EGO18652.1 - 8.8e-09 35.4 0.0 1.2e-05 25.3 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF1325 PF07039.6 EGO18652.1 - 0.00064 19.3 0.0 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 SGF29 tudor-like domain YajC PF02699.10 EGO18652.1 - 0.034 13.8 0.7 0.084 12.5 0.5 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit 53-BP1_Tudor PF09038.5 EGO18652.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor PTCB-BRCT PF12738.2 EGO18652.1 - 0.071 12.9 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 twin BRCT domain OTU PF02338.14 EGO18654.1 - 6.1e-09 36.5 0.0 9.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Exo_endo_phos PF03372.18 EGO18655.1 - 0.00018 21.5 0.0 0.00018 21.5 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UCH PF00443.24 EGO18657.1 - 6.7e-31 107.3 1.2 3.2e-30 105.1 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO18657.1 - 4.7e-10 39.4 1.9 6.6e-05 22.4 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGO18657.1 - 6.5e-08 31.8 0.7 1.4e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.7 EGO18657.1 - 4.6e-05 23.7 0.9 0.015 15.6 0.0 3.1 2 0 0 2 2 2 2 DUSP domain LUC7 PF03194.10 EGO18658.1 - 1.4e-69 234.4 2.2 2e-69 233.9 1.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Ada3 PF10198.4 EGO18658.1 - 0.048 13.4 0.6 0.092 12.5 0.4 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 PRP38_assoc PF12871.2 EGO18658.1 - 0.38 11.3 31.5 0.081 13.4 19.4 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FliT PF05400.8 EGO18658.1 - 1.4 9.3 6.0 29 5.1 4.1 2.5 1 1 0 1 1 1 0 Flagellar protein FliT Ank_3 PF13606.1 EGO18659.1 - 6.6e-11 41.3 0.0 0.011 15.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EGO18659.1 - 4.5e-10 39.7 0.0 3.8e-09 36.7 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO18659.1 - 4.7e-10 39.6 0.3 6.5e-07 29.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO18659.1 - 1.7e-09 37.6 0.1 1.3e-06 28.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO18659.1 - 1.3e-07 31.0 0.0 0.00025 20.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat BCS1_N PF08740.6 EGO18660.1 - 2.1e-49 167.6 0.5 2.9e-49 167.2 0.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGO18660.1 - 3.4e-20 72.5 0.0 8e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO18660.1 - 7.5e-05 23.5 0.0 0.00017 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGO18660.1 - 9.4e-05 21.8 0.0 0.00035 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO18660.1 - 0.00041 20.2 0.0 0.00092 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO18660.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO18660.1 - 0.002 18.1 0.1 0.0048 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO18660.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO18660.1 - 0.0064 15.6 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EGO18660.1 - 0.0074 16.0 0.0 0.037 13.7 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EGO18660.1 - 0.017 15.2 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EGO18660.1 - 0.024 14.9 0.1 0.056 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGO18660.1 - 0.028 13.9 0.0 0.082 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EGO18660.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO18660.1 - 0.035 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGO18660.1 - 0.059 13.0 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EGO18660.1 - 0.079 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EGO18660.1 - 0.086 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EGO18660.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EGO18660.1 - 0.09 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 EGO18660.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGO18660.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.1 EGO18660.1 - 0.12 12.2 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain WBS_methylT PF12589.3 EGO18661.1 - 1.5e-19 70.2 7.9 2.6e-19 69.5 5.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGO18661.1 - 1.5e-09 38.2 0.0 3.4e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO18661.1 - 2.5e-06 27.3 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO18661.1 - 2.6e-05 23.8 0.0 4.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO18661.1 - 8.3e-05 23.0 0.0 0.00025 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO18661.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO18661.1 - 0.0023 18.2 0.0 0.0055 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EGO18661.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.11 EGO18662.1 - 1.4e-37 128.5 0.0 2e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component XAP5 PF04921.9 EGO18663.1 - 7.5e-95 317.0 7.2 7.5e-95 317.0 5.0 2.2 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4618 PF15397.1 EGO18663.1 - 0.51 9.6 13.2 0.049 12.9 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Mito_carr PF00153.22 EGO18664.1 - 8.5e-45 150.4 0.1 1.1e-14 53.8 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.4 EGO18664.1 - 2.8e-15 55.5 0.1 2.6e-09 35.7 0.4 3.0 2 1 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.17 EGO18665.1 - 5.5e-36 124.3 0.4 1.9e-34 119.2 0.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Exo_endo_phos PF03372.18 EGO18666.1 - 6.6e-17 62.2 0.2 1.2e-16 61.4 0.0 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.15 EGO18667.1 - 1.7e-10 40.8 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mannosyl_trans PF05007.8 EGO18668.1 - 1.4e-65 221.5 10.1 1.9e-65 221.0 7.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGO18668.1 - 6.8e-10 38.3 7.7 1.7e-09 37.0 5.4 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Arf PF00025.16 EGO18669.1 - 6.4e-68 227.4 0.0 7.2e-68 227.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO18669.1 - 3.6e-11 42.6 0.0 4.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGO18669.1 - 1.4e-10 40.4 0.2 2.7e-07 29.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGO18669.1 - 9.7e-08 32.5 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO18669.1 - 3e-07 30.3 0.0 9.1e-07 28.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EGO18669.1 - 1.1e-06 28.1 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGO18669.1 - 3.3e-05 23.1 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGO18669.1 - 0.004 16.6 0.0 0.13 11.7 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGO18669.1 - 0.015 14.7 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGO18670.1 - 2e-21 76.0 0.0 2.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EGO18670.1 - 9.5e-13 47.7 0.0 1.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO18670.1 - 1.3e-07 31.0 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO18670.1 - 2.6e-05 24.1 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO18670.1 - 0.0015 19.0 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGO18670.1 - 0.0077 16.2 0.3 0.017 15.1 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EGO18670.1 - 0.0086 15.4 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO18670.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGO18670.1 - 0.03 13.0 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus FeoB_N PF02421.13 EGO18670.1 - 0.037 13.3 0.0 0.078 12.2 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EGO18670.1 - 0.044 13.9 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EGO18670.1 - 0.059 13.1 0.0 2.2 8.0 0.0 2.2 1 1 1 2 2 2 0 Dynamin family FRG1 PF06229.7 EGO18671.1 - 1.1e-25 90.1 0.1 1.1e-25 90.1 0.0 1.8 2 0 0 2 2 2 1 FRG1-like family DUF1754 PF08555.5 EGO18671.1 - 6.7e-05 23.4 4.1 0.16 12.5 0.8 2.4 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Fascin PF06268.8 EGO18671.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Fascin domain ATP-synt_D PF01813.12 EGO18672.1 - 3.7e-65 219.1 3.9 4.6e-65 218.8 2.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D PASTA PF03793.14 EGO18672.1 - 0.12 12.0 0.1 0.37 10.4 0.1 1.9 1 0 0 1 1 1 0 PASTA domain Cpn60_TCP1 PF00118.19 EGO18673.1 - 1.6e-142 475.5 12.6 1.9e-142 475.3 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3599 PF12206.3 EGO18673.1 - 0.049 13.8 0.4 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3599) UFD1 PF03152.9 EGO18674.1 - 1.9e-66 222.5 0.0 2.5e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EGO18674.1 - 0.00029 20.4 0.0 0.011 15.4 0.0 2.3 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 NMT PF01233.14 EGO18675.1 - 1.6e-77 258.6 0.0 2.5e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EGO18675.1 - 8e-73 243.8 0.0 6e-72 241.0 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EGO18675.1 - 4.7e-06 26.4 0.0 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain HeLo PF14479.1 EGO18676.1 - 0.13 12.0 3.0 0.15 11.7 2.1 1.0 1 0 0 1 1 1 0 Prion-inhibition and propagation Sigma70_ner PF04546.8 EGO18676.1 - 0.24 10.9 4.3 0.27 10.8 3.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region HSP90 PF00183.13 EGO18676.1 - 0.5 8.7 5.6 0.52 8.6 3.9 1.0 1 0 0 1 1 1 0 Hsp90 protein Tom37_C PF11801.3 EGO18676.1 - 0.58 9.9 6.9 0.67 9.7 4.8 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain CP12 PF02672.10 EGO18676.1 - 0.95 9.9 5.4 1.3 9.5 3.8 1.2 1 0 0 1 1 1 0 CP12 domain Herpes_DNAp_acc PF04929.7 EGO18676.1 - 1.9 7.3 6.9 1.9 7.3 4.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor YqfQ PF14181.1 EGO18676.1 - 3 7.8 7.8 3.4 7.6 5.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein Dsh_C PF12316.3 EGO18676.1 - 3.8 7.5 8.4 3.9 7.5 5.8 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal OGG_N PF07934.7 EGO18677.1 - 2.7e-29 101.5 0.1 4.9e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGO18677.1 - 2.1e-15 56.8 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGO18677.1 - 0.0047 16.5 0.1 0.089 12.5 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF4511 PF14974.1 EGO18677.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) NPR2 PF06218.6 EGO18678.1 - 3.1e-112 375.4 0.0 4.6e-96 322.1 0.0 2.3 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 EGO18678.1 - 0.00076 18.1 0.5 0.035 12.6 0.0 2.3 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 RTC PF01137.16 EGO18679.1 - 4.7e-67 225.0 0.0 5.4e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EGO18679.1 - 5.2e-32 109.9 0.0 8.3e-32 109.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain ThiF PF00899.16 EGO18680.1 - 6.8e-38 129.5 0.1 1.7e-37 128.2 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EGO18680.1 - 5.4e-27 93.3 0.1 8.6e-27 92.7 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EGO18680.1 - 3.7e-23 80.8 0.6 3.7e-23 80.8 0.4 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGO18680.1 - 8.2e-17 60.3 1.9 1.8e-16 59.2 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EGO18680.1 - 0.0023 18.0 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EGO18680.1 - 0.0051 16.3 0.7 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EGO18680.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Pyr_redox PF00070.22 EGO18680.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGO18680.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 1-cysPrx_C PF10417.4 EGO18680.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin DAO PF01266.19 EGO18680.1 - 0.18 10.6 0.1 0.33 9.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Zn_ribbon_recom PF13408.1 EGO18681.1 - 0.11 12.7 4.4 0.18 12.0 3.0 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2039 PF10217.4 EGO18681.1 - 0.88 9.6 8.1 0.62 10.1 1.8 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-B_box PF00643.19 EGO18681.1 - 1.7 8.5 11.1 2.7 7.9 4.4 2.7 2 1 0 2 2 2 0 B-box zinc finger LEA_2 PF03168.8 EGO18682.1 - 3.9e-08 33.5 0.0 6.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.2 EGO18682.1 - 3.6e-05 22.7 0.0 4.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF1356 PF07092.7 EGO18682.1 - 0.008 15.3 1.0 0.012 14.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DivIC PF04977.10 EGO18683.1 - 0.051 13.0 0.1 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Telomere_Sde2 PF13019.1 EGO18684.1 - 1.5e-18 66.9 0.0 1.6e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing DEAD PF00270.24 EGO18685.1 - 3.2e-10 39.7 0.0 5.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNAPc19 PF15497.1 EGO18689.1 - 0.069 13.3 0.5 0.07 13.3 0.3 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 zf-CCHC_3 PF13917.1 EGO18690.1 - 4.4e-06 26.3 1.6 4.4e-06 26.3 1.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EGO18690.1 - 4.9e-05 23.0 5.5 8.1e-05 22.3 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO18690.1 - 0.31 10.5 4.1 0.53 9.8 2.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger JmjC PF02373.17 EGO18691.1 - 1.6e-11 44.4 1.2 1.4e-10 41.3 0.0 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase SLIDE PF09111.5 EGO18692.1 - 0.006 16.3 3.5 0.17 11.6 2.4 2.0 1 1 0 1 1 1 1 SLIDE AD PF09793.4 EGO18692.1 - 0.011 15.5 0.3 0.011 15.5 0.2 1.6 2 0 0 2 2 2 0 Anticodon-binding domain NPV_P10 PF05531.7 EGO18692.1 - 0.042 14.0 3.1 0.18 12.0 1.3 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein eRF1_1 PF03463.10 EGO18692.1 - 0.044 13.3 0.2 0.061 12.8 0.1 1.4 1 1 0 1 1 1 0 eRF1 domain 1 DUF2408 PF10303.4 EGO18692.1 - 0.19 11.8 4.4 0.25 11.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ToxN_toxin PF13958.1 EGO18692.1 - 0.21 11.2 1.8 0.37 10.4 1.0 1.7 1 1 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system TBCA PF02970.11 EGO18692.1 - 0.31 11.1 3.6 0.61 10.1 2.3 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor A DUF745 PF05335.8 EGO18692.1 - 0.42 10.1 2.6 0.71 9.3 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF648 PF04890.8 EGO18692.1 - 0.6 9.2 3.6 0.65 9.1 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) ACCA PF03255.9 EGO18692.1 - 0.91 9.0 3.8 0.5 9.9 0.5 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-R PF06729.7 EGO18692.1 - 0.93 9.1 4.2 2 8.0 0.1 2.0 1 1 1 2 2 2 0 Kinetochore component, CENP-R APG6 PF04111.7 EGO18692.1 - 0.98 8.3 8.4 1.1 8.1 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS6_N PF14661.1 EGO18692.1 - 1.5 8.0 6.2 1.7 7.9 4.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1664 PF07889.7 EGO18692.1 - 3.1 7.5 6.3 3.9 7.2 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 EGO18692.1 - 7.6 6.9 13.6 0.31 11.4 1.9 2.5 1 1 1 2 2 2 0 SlyX Pkinase PF00069.20 EGO18694.1 - 3.3e-25 88.7 0.0 4.9e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO18694.1 - 4.2e-06 26.0 0.0 9.5e-06 24.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGO18694.1 - 0.058 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FMO-like PF00743.14 EGO18695.1 - 4e-20 71.5 0.0 1.3e-18 66.4 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO18695.1 - 2.1e-18 67.1 0.0 4.7e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO18695.1 - 1.7e-08 33.8 0.0 6.6e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO18695.1 - 6e-08 32.5 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO18695.1 - 4.5e-06 26.6 0.0 7.1e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO18695.1 - 0.0002 20.4 0.0 0.00037 19.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EGO18695.1 - 0.00065 18.7 0.3 0.0015 17.5 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO18695.1 - 0.0015 17.4 1.7 0.1 11.4 0.5 2.2 1 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGO18695.1 - 0.0081 15.9 1.4 0.072 12.8 0.0 2.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGO18695.1 - 0.015 14.3 0.2 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EGO18695.1 - 0.054 13.9 1.7 0.27 11.6 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGO18695.1 - 0.11 12.6 0.0 9.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 EGO18695.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain GIDA PF01134.17 EGO18695.1 - 0.22 10.3 0.6 4.3 6.0 0.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Vac_ImportDeg PF09783.4 EGO18696.1 - 1.8e-57 193.6 0.0 3.3e-52 176.5 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein Ras PF00071.17 EGO18697.1 - 7.3e-50 168.5 0.0 8.7e-50 168.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO18697.1 - 4.6e-16 59.3 0.0 7.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO18697.1 - 3.6e-10 39.3 0.0 4.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO18697.1 - 0.00028 20.0 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGO18697.1 - 0.00067 18.4 2.1 0.59 8.7 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 EGO18697.1 - 0.017 15.2 0.1 0.15 12.2 0.1 2.2 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EGO18697.1 - 0.028 13.7 0.1 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EGO18697.1 - 0.035 14.2 0.1 0.13 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EGO18697.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 EGO18697.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 STAS domain MFS_1 PF07690.11 EGO18698.1 - 7.5e-52 176.1 41.6 7.5e-52 176.1 28.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO18698.1 - 1.6e-16 59.6 17.2 1.7e-16 59.5 11.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO18698.1 - 4.4e-13 48.6 12.8 4.4e-13 48.6 8.8 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3040 PF11239.3 EGO18698.1 - 0.094 12.7 0.2 0.094 12.7 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) Neurensin PF14927.1 EGO18698.1 - 3.7 6.9 7.9 0.28 10.5 0.2 2.8 2 1 1 3 3 3 0 Neurensin DUF4097 PF13349.1 EGO18698.1 - 9 5.8 8.2 1.1 8.8 0.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) Ig_J_chain PF15097.1 EGO18700.1 - 0.65 9.5 3.7 0.97 9.0 0.2 2.1 2 0 0 2 2 2 0 Immunoglobulin J chain CBM_19 PF03427.8 EGO18700.1 - 6.2 6.6 21.3 0.94 9.3 1.5 3.4 2 1 1 3 3 3 0 Carbohydrate binding domain (family 19) DUF1342 PF07072.6 EGO18714.1 - 0.027 14.1 0.1 0.031 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) DUF434 PF04256.7 EGO18714.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) DUF1342 PF07072.6 EGO18718.1 - 0.027 14.1 0.1 0.031 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) DUF434 PF04256.7 EGO18718.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) zf-CCHC PF00098.18 EGO18721.1 - 8.7e-08 31.7 2.7 1.7e-07 30.8 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO18721.1 - 4.9e-06 26.5 1.3 1.2e-05 25.2 0.2 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO18721.1 - 0.0051 16.5 2.3 0.01 15.5 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle NYD-SP28_assoc PF14775.1 EGO18721.1 - 0.074 12.7 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain zf-CCHC_4 PF14392.1 EGO18721.1 - 0.2 11.3 2.6 0.42 10.3 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EGO18722.1 - 2e-24 85.9 61.3 1e-15 57.3 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SAP PF02037.22 EGO18725.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 SAP domain RAP1 PF07218.6 EGO18725.1 - 1.9 6.4 8.7 2.7 6.0 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDE_1 PF03184.14 EGO18726.1 - 4.2e-29 101.2 0.0 4.8e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO18726.1 - 0.0006 19.5 0.0 0.001 18.8 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease ketoacyl-synt PF00109.21 EGO18727.1 - 1.4e-55 188.5 0.0 3e-55 187.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO18727.1 - 4.4e-48 164.2 0.0 6.9e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO18727.1 - 5e-39 133.8 0.0 5e-35 120.8 0.0 3.1 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 EGO18727.1 - 3.3e-36 124.7 0.1 2.2e-29 102.5 0.0 3.9 4 0 0 4 4 4 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EGO18727.1 - 4.5e-29 101.1 0.0 7.3e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGO18727.1 - 1.6e-28 98.9 0.0 3.4e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGO18727.1 - 8.9e-24 84.1 0.0 1.9e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EGO18727.1 - 4.9e-11 42.5 0.0 1.7e-10 40.7 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGO18727.1 - 4.3e-08 33.3 0.1 1.1e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGO18727.1 - 0.00075 18.5 0.1 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGO18727.1 - 0.0093 15.6 0.0 0.041 13.5 0.0 2.2 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 EGO18727.1 - 0.16 10.7 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGO18727.1 - 0.35 9.5 0.0 1.2 7.7 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family gag_pre-integrs PF13976.1 EGO18733.1 - 2.4e-10 39.8 0.1 3.9e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4381 PF14316.1 EGO18736.1 - 0.051 13.6 0.2 0.057 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Chromo PF00385.19 EGO18738.1 - 1.1e-08 34.6 0.3 1.7e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2461 PF09365.5 EGO18740.1 - 7e-54 182.4 0.2 1.1e-52 178.5 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical protein (DUF2461) zf-C3H1 PF10650.4 EGO18740.1 - 0.76 9.3 2.6 1.4 8.4 1.8 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain FLO_LFY PF01698.11 EGO18740.1 - 0.92 8.2 7.6 1.3 7.7 5.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3994 PF13159.1 EGO18740.1 - 3 8.1 13.6 0.16 12.2 5.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) p450 PF00067.17 EGO18742.1 - 4.8e-51 173.7 0.0 5.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.17 EGO18743.1 - 1e-12 48.5 0.0 1.9e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO18743.1 - 0.004 16.9 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.23 EGO18746.1 - 6.4e-95 317.9 0.2 2.4e-94 316.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO18746.1 - 4.4e-22 78.8 0.2 1.7e-20 73.7 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Crp PF00325.15 EGO18746.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family MFS_1 PF07690.11 EGO18747.1 - 3.7e-40 137.7 52.9 3.7e-40 137.7 36.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO18747.1 - 1.4e-21 76.4 24.8 1.8e-21 75.9 17.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO18747.1 - 3.8e-13 48.8 12.5 3.8e-13 48.8 8.7 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Mpv17_PMP22 PF04117.7 EGO18747.1 - 3.6 7.3 0.0 3.6 7.3 0.0 3.8 4 1 0 4 4 4 0 Mpv17 / PMP22 family V-SNARE PF05008.10 EGO18748.1 - 5.3e-22 77.7 9.4 2.8e-21 75.4 3.3 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGO18748.1 - 1.3e-16 60.4 3.7 1.3e-16 60.4 2.5 2.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGO18748.1 - 0.00015 21.3 0.4 0.00015 21.3 0.2 1.9 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 EGO18748.1 - 0.017 13.2 0.2 0.026 12.6 0.1 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF2275 PF10039.4 EGO18748.1 - 0.031 14.1 0.3 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) MCE PF02470.15 EGO18748.1 - 0.079 12.9 0.2 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 mce related protein DUF3770 PF12603.3 EGO18748.1 - 0.1 11.7 2.6 2.3 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) OppC_N PF12911.2 EGO18748.1 - 0.13 11.6 1.7 0.25 10.7 1.2 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF912 PF06024.7 EGO18748.1 - 0.22 11.6 1.4 1.8 8.6 0.1 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3619 PF12279.3 EGO18748.1 - 1.3 9.1 6.1 3 7.9 0.8 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3619) Vpu PF00558.14 EGO18748.1 - 2.3 7.8 5.0 5.4 6.6 3.4 1.7 1 0 0 1 1 1 0 Vpu protein FliJ PF02050.11 EGO18748.1 - 4.6 7.3 11.5 9.9 6.2 0.4 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Peroxin-3 PF04882.7 EGO18749.1 - 3.3e-62 210.6 0.0 1.8e-32 112.6 0.0 2.1 2 0 0 2 2 2 2 Peroxin-3 Med15 PF09606.5 EGO18751.1 - 0.32 9.1 19.0 0.37 8.9 13.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PTPlike_phytase PF14566.1 EGO18751.1 - 0.64 10.0 9.6 0.76 9.8 4.8 1.8 1 1 1 2 2 2 0 Inositol hexakisphosphate PEHE PF15275.1 EGO18751.1 - 5.5 7.4 15.0 7.5 7.0 10.0 1.6 1 1 1 2 2 2 0 PEHE domain Thioesterase PF00975.15 EGO18753.1 - 4.7e-10 40.0 0.1 2.2e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGO18753.1 - 3.6e-08 33.5 0.1 7.9e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO18753.1 - 0.04 13.6 0.0 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family KR PF08659.5 EGO18754.1 - 3.7e-13 49.5 0.2 4.4e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGO18754.1 - 4.9e-09 36.3 0.2 6.3e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ketoacyl-synt PF00109.21 EGO18755.1 - 1.2e-37 129.7 0.2 2.2e-37 128.9 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGO18755.1 - 4.2e-15 55.6 0.0 7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGO18755.1 - 4.5e-06 25.8 0.1 8.7e-06 24.9 0.0 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGO18755.1 - 0.0023 17.5 0.6 0.0053 16.3 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RVP_2 PF08284.6 EGO18757.1 - 2.6e-07 30.6 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO18757.1 - 3.3e-07 30.0 0.0 4.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO18757.1 - 9.8e-05 22.7 0.1 0.00017 22.0 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO18757.1 - 0.064 12.8 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DKNYY PF13644.1 EGO18758.1 - 0.023 14.9 0.9 0.025 14.8 0.6 1.1 1 0 0 1 1 1 0 DKNYY family gag-asp_proteas PF13975.1 EGO18759.1 - 1.7e-08 34.1 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO18759.1 - 3.6e-08 33.4 0.0 4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO18759.1 - 6.3e-06 26.6 0.1 1.1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease SEEEED PF14797.1 EGO18763.1 - 0.015 15.4 9.6 0.022 14.9 6.7 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex BLVR PF06375.6 EGO18763.1 - 1.2 8.9 9.3 1.7 8.4 6.4 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Retrotrans_gag PF03732.12 EGO18765.1 - 2.7e-07 30.5 1.2 4.9e-07 29.7 0.2 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO18765.1 - 3e-05 23.7 2.0 7.2e-05 22.5 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle BUD22 PF09073.5 EGO18766.1 - 0.021 13.8 4.1 0.031 13.3 2.8 1.2 1 0 0 1 1 1 0 BUD22 RTX_C PF08339.5 EGO18768.1 - 0.19 11.4 0.0 8.1 6.1 0.0 2.2 2 0 0 2 2 2 0 RTX C-terminal domain Retrotrans_gag PF03732.12 EGO18770.1 - 6.1e-08 32.6 0.4 6.1e-08 32.6 0.3 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EGO18773.1 - 7.7e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO18773.1 - 2e-05 24.9 0.0 2.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO18773.1 - 0.0044 16.9 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Cyclin_N PF00134.18 EGO18777.1 - 5.9e-24 84.0 2.4 3.7e-20 71.7 0.0 3.0 2 1 1 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO18777.1 - 6.4e-16 58.3 0.0 7.4e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain MULE PF10551.4 EGO18779.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.7 1 1 0 1 1 1 1 MULE transposase domain Retrotrans_gag PF03732.12 EGO18780.1 - 0.011 15.7 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.21 EGO18781.1 - 0.00025 21.1 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain ATG11 PF10377.4 EGO18781.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 gag-asp_proteas PF13975.1 EGO18783.1 - 0.00027 20.6 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO18783.1 - 0.00092 19.6 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO18783.1 - 0.049 13.1 0.0 0.068 12.7 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease Spore_YpjB PF09577.5 EGO18784.1 - 0.069 12.7 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Retrotrans_gag PF03732.12 EGO18785.1 - 4.2 7.5 5.6 58 3.8 3.9 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein Angiomotin_C PF12240.3 EGO18786.1 - 0.016 14.6 0.1 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Angiomotin C terminal PMT_C PF11647.3 EGO18786.1 - 0.069 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 ketoacyl-synt PF00109.21 EGO18788.1 - 6.3e-53 179.8 0.0 9.5e-51 172.7 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO18788.1 - 1.4e-40 139.6 0.0 2.1e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO18788.1 - 6.7e-33 113.8 0.0 1.7e-32 112.5 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGO18788.1 - 2.8e-27 95.6 0.0 9.2e-22 77.5 0.0 2.4 1 1 0 2 2 2 2 Polyketide synthase dehydratase adh_short PF00106.20 EGO18788.1 - 1.4e-26 93.3 0.0 2.7e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGO18788.1 - 2.4e-26 91.9 0.0 4.5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EGO18788.1 - 1.5e-08 35.1 0.0 4.3e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EGO18788.1 - 4.3e-05 23.6 0.1 0.00028 21.0 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGO18788.1 - 0.00012 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain zf-C4pol PF14260.1 EGO18792.1 - 0.024 14.6 2.4 0.024 14.6 1.7 1.5 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-ribbon_3 PF13248.1 EGO18792.1 - 0.078 12.2 6.1 0.89 8.8 1.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-DHHC PF01529.15 EGO18792.1 - 2.4 7.5 8.3 3.7 6.9 5.7 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase zf-B_box PF00643.19 EGO18792.1 - 4.5 7.2 9.2 11 6.0 6.4 1.6 1 1 0 1 1 1 0 B-box zinc finger zf-CCHC PF00098.18 EGO18793.1 - 5.2e-08 32.4 2.8 1.1e-07 31.4 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO18793.1 - 8.2e-07 29.0 0.0 8.2e-07 29.0 0.0 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_6 PF15288.1 EGO18793.1 - 0.1 12.3 1.3 0.21 11.2 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO18793.1 - 0.1 12.3 7.8 0.36 10.6 5.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO18793.1 - 0.26 10.9 1.2 0.54 9.9 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle CofC PF01983.11 EGO18796.1 - 0.045 12.7 0.4 0.063 12.2 0.3 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like zf-C2HC_2 PF13913.1 EGO18797.1 - 0.038 13.6 0.5 0.086 12.5 0.4 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Nairovirus_M PF07948.6 EGO18797.1 - 0.35 8.9 0.1 0.51 8.4 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Cyclin_N PF00134.18 EGO18798.1 - 5.8e-42 142.2 0.4 5.8e-42 142.2 0.3 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO18798.1 - 1.3e-15 57.4 0.0 2.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain MFS_1 PF07690.11 EGO18799.1 - 4.2e-06 25.7 28.0 8.5e-06 24.7 18.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily InaF-motif PF15018.1 EGO18799.1 - 0.014 14.8 5.6 0.5 9.8 0.6 2.7 2 0 0 2 2 2 0 TRP-interacting helix DUF1664 PF07889.7 EGO18799.1 - 0.023 14.4 0.9 0.038 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nuc_H_symport PF03825.11 EGO18799.1 - 0.083 11.6 2.8 0.05 12.3 0.5 1.5 1 1 0 1 1 1 0 Nucleoside H+ symporter ATG22 PF11700.3 EGO18799.1 - 0.36 9.2 11.5 0.47 8.8 7.9 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EGO18799.1 - 6.3 6.6 12.3 0.53 10.1 0.3 3.2 2 1 1 3 3 3 0 MFS_1 like family DEC-1_N PF04625.8 EGO18803.1 - 0.018 13.7 5.4 0.02 13.6 3.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Leader_Trp PF08255.6 EGO18803.1 - 0.26 11.0 2.0 0.63 9.8 1.4 1.6 1 0 0 1 1 1 0 Trp-operon Leader Peptide NAD_binding_4 PF07993.7 EGO18805.1 - 2.4e-29 102.0 0.0 3.6e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO18805.1 - 4.2e-18 64.9 0.4 3.4e-15 55.3 0.2 3.2 2 1 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EGO18805.1 - 2.5e-09 36.9 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO18805.1 - 0.0032 16.2 0.0 0.0055 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGO18805.1 - 0.052 13.4 0.1 0.24 11.2 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EGO18805.1 - 0.082 13.2 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EGO18805.1 - 0.11 12.1 0.3 0.36 10.4 0.2 1.9 1 1 0 1 1 1 0 KR domain FHA PF00498.21 EGO18806.1 - 3.7e-05 23.7 0.0 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 FHA domain p450 PF00067.17 EGO18810.1 - 9.4e-30 103.5 0.0 1.4e-29 102.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Tet_JBP PF12851.2 EGO18812.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily NAD_binding_4 PF07993.7 EGO18816.1 - 3.1e-31 108.1 0.0 4.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO18816.1 - 3.8e-29 101.3 0.0 2.8e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGO18816.1 - 2.6e-10 40.1 0.0 5.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GH3 PF03321.8 EGO18816.1 - 0.025 13.1 0.0 0.046 12.2 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter zf-CCHC PF00098.18 EGO18818.1 - 2.7e-05 23.8 4.0 5.6e-05 22.8 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO18818.1 - 0.53 10.0 5.0 1.2 8.9 3.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_3 PF12776.2 EGO18829.1 - 0.075 13.6 0.2 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain M_domain PF12938.2 EGO18830.1 - 0.1 12.3 0.6 0.14 11.9 0.4 1.1 1 0 0 1 1 1 0 M domain of GW182 Transformer PF06495.6 EGO18832.1 - 0.13 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Retrotrans_gag PF03732.12 EGO18836.1 - 0.009 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EGO18837.1 - 2.2e-06 28.0 0.0 2.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO18837.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO18837.1 - 6.2e-05 22.9 0.0 7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease SprB PF13573.1 EGO18837.1 - 0.76 9.4 3.9 3.3 7.3 2.7 1.9 1 1 0 1 1 1 0 SprB repeat zf-C2H2 PF00096.21 EGO18842.1 - 0.02 15.1 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO18842.1 - 0.043 14.1 0.2 0.98 9.9 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3658 PF12395.3 EGO18843.1 - 0.083 12.4 2.2 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF4218 PF13960.1 EGO18844.1 - 0.0077 15.6 0.1 0.014 14.7 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) IncA PF04156.9 EGO18845.1 - 0.019 14.5 4.7 1.4 8.5 3.0 2.2 1 1 1 2 2 2 0 IncA protein CTNNBL PF08216.6 EGO18845.1 - 1.3 8.6 7.2 1.1 8.8 1.4 2.3 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Uds1 PF15456.1 EGO18845.1 - 5.2 7.0 10.8 6.9 6.6 3.6 2.4 1 1 2 3 3 3 0 Up-regulated During Septation DUF4381 PF14316.1 EGO18849.1 - 0.037 14.1 0.3 0.038 14.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FHA PF00498.21 EGO18855.1 - 1.9e-07 31.1 0.0 3.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Orthoreo_P10 PF07204.6 EGO18856.1 - 0.18 11.5 0.6 0.3 10.8 0.3 1.3 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Fungal_trans PF04082.13 EGO18857.1 - 1e-10 40.9 0.6 2e-10 40.0 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Copper-fist PF00649.13 EGO18857.1 - 0.091 11.9 1.6 0.21 10.8 1.1 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain Zn_clus PF00172.13 EGO18857.1 - 0.23 11.4 6.8 0.41 10.6 4.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L24e PF01246.15 EGO18859.1 - 1.2e-30 105.1 3.2 2.8e-30 103.9 2.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EGO18859.1 - 0.028 14.0 5.0 0.047 13.3 3.5 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PCP_red PF08369.5 EGO18859.1 - 0.098 12.5 0.1 0.098 12.5 0.1 2.2 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit GAT PF03127.9 EGO18859.1 - 0.12 12.3 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 GAT domain Cpn60_TCP1 PF00118.19 EGO18860.1 - 2.7e-153 511.0 1.8 3.1e-153 510.8 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.7 EGO18860.1 - 0.075 12.6 0.0 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Glyco_hydro_1 PF00232.13 EGO18862.1 - 6.9e-158 525.5 0.6 8.3e-158 525.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GFO_IDH_MocA PF01408.17 EGO18863.1 - 3.1e-12 47.0 0.1 5.4e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO18863.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EGO18863.1 - 0.034 14.5 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EGO18863.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase SHOCT PF09851.4 EGO18864.1 - 0.018 14.4 1.3 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 Short C-terminal domain Methyltransf_11 PF08241.7 EGO18865.1 - 1e-07 32.3 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO18865.1 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO18865.1 - 7.5e-05 23.1 0.0 0.00014 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO18865.1 - 8e-05 21.8 0.0 0.00023 20.3 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO18865.1 - 8.5e-05 22.1 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO18865.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain VIT PF08487.5 EGO18866.1 - 2.2e-18 66.0 0.0 4.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 EGO18866.1 - 9.8e-18 64.3 0.0 5.7e-16 58.5 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO18866.1 - 1.4e-13 50.9 0.0 3.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGO18866.1 - 7.6e-13 48.9 0.0 1.8e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EGO18866.1 - 3.4e-07 29.6 0.0 8.2e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EGO18866.1 - 0.0032 16.6 0.8 1.1 8.3 0.1 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein PSD2 PF07624.6 EGO18866.1 - 0.098 12.3 1.0 6.9 6.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Abhydrolase_6 PF12697.2 EGO18869.1 - 2.8e-18 66.6 0.0 3.3e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO18869.1 - 1.8e-08 34.2 0.0 2.6e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO18869.1 - 1.7e-05 24.4 0.1 0.0065 16.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO18869.1 - 0.0081 15.4 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family OPT PF03169.10 EGO18870.1 - 6.8e-144 480.6 53.2 8e-144 480.4 36.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4470 PF14737.1 EGO18873.1 - 5.7e-24 83.7 0.0 1.2e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGO18873.1 - 4.9e-10 39.1 14.7 1.3e-09 37.7 10.2 1.8 1 0 0 1 1 1 1 MYND finger DGOK PF05035.7 EGO18874.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase DUF2697 PF10906.3 EGO18875.1 - 0.013 15.4 0.1 1.6 8.8 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2697) Claudin_3 PF06653.6 EGO18876.1 - 0.066 12.9 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like FAD_binding_3 PF01494.14 EGO18878.1 - 1.7e-70 237.8 0.0 2.1e-69 234.3 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO18878.1 - 1.4e-14 54.0 0.0 3.6e-14 52.7 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EGO18878.1 - 1.8e-07 30.4 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO18878.1 - 1.7e-06 27.3 0.0 2.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EGO18878.1 - 2.2e-05 23.1 0.0 3.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO18878.1 - 7e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO18878.1 - 0.00019 21.7 0.0 0.00044 20.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO18878.1 - 0.00049 19.2 0.0 0.00071 18.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO18878.1 - 0.0009 19.1 0.0 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO18878.1 - 0.0011 17.9 0.1 0.0016 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGO18878.1 - 0.0027 17.7 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO18878.1 - 0.0035 16.3 0.1 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGO18878.1 - 0.0062 16.3 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.17 EGO18878.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Omega-toxin PF06357.6 EGO18878.1 - 0.023 14.2 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Omega-atracotoxin Trp_halogenase PF04820.9 EGO18878.1 - 0.033 12.8 0.0 0.06 11.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Methyltransf_2 PF00891.13 EGO18879.1 - 1.3e-32 112.8 0.0 1.9e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGO18879.1 - 1.9e-06 28.4 0.0 6.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO18879.1 - 7.8e-06 25.7 0.0 2.7e-05 23.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO18879.1 - 2.4e-05 23.9 0.0 5.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO18879.1 - 3.7e-05 23.1 0.0 6.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO18879.1 - 0.0031 17.9 0.0 0.0095 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO18879.1 - 0.0041 17.5 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 EGO18879.1 - 0.0068 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G FmrO PF07091.6 EGO18879.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) HTH_24 PF13412.1 EGO18879.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 EGO18879.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 MarR family Aldedh PF00171.17 EGO18880.1 - 4.1e-146 486.9 0.0 5e-146 486.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO18880.1 - 0.01 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) SecY PF00344.15 EGO18881.1 - 4.5e-98 328.3 9.1 5.6e-98 328.0 6.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EGO18881.1 - 1.6e-19 69.1 0.2 6e-19 67.2 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p Prokineticin PF06607.6 EGO18881.1 - 0.26 11.3 2.1 13 5.9 0.3 3.5 3 1 1 4 4 4 0 Prokineticin UNC-93 PF05978.11 EGO18882.1 - 4e-14 52.4 7.1 1.3e-13 50.7 4.9 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGO18882.1 - 9.5e-14 50.8 33.5 1.8e-13 49.9 23.2 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily PI-PLC-X PF00388.14 EGO18883.1 - 3.8e-53 178.8 0.0 8.7e-53 177.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGO18883.1 - 2.5e-40 137.1 0.0 5e-40 136.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGO18883.1 - 9.9e-09 34.9 0.0 2.9e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Chlam_OMP6 PF03504.8 EGO18883.1 - 0.0081 16.4 0.2 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 Chlamydia cysteine-rich outer membrane protein 6 Lipase_GDSL PF00657.17 EGO18884.1 - 3.9e-09 36.6 1.1 8.3e-09 35.6 0.8 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGO18884.1 - 6.8e-05 23.0 0.4 0.0001 22.4 0.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cellulase PF00150.13 EGO18885.1 - 1.4e-14 53.9 7.5 2e-14 53.5 5.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGO18885.1 - 6.1e-05 23.3 0.0 0.00022 21.6 0.0 1.9 1 1 0 1 1 1 1 Sugar-binding cellulase-like p450 PF00067.17 EGO18886.1 - 1.8e-80 270.7 0.0 2.4e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aromatic_hydrox PF11723.3 EGO18889.1 - 0.067 12.4 1.3 0.073 12.3 0.1 1.6 2 0 0 2 2 2 0 Homotrimeric ring hydroxylase DUF3505 PF12013.3 EGO18891.1 - 1.3e-07 31.7 1.0 3.5e-06 27.2 0.2 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Pkinase PF00069.20 EGO18894.1 - 2.1e-08 33.6 0.0 3.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO18894.1 - 1.3e-05 24.4 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGO18894.1 - 2.9e-05 23.7 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGO18894.1 - 4.9e-05 23.1 0.0 7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO18894.1 - 0.0072 15.4 0.1 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_3 PF00933.16 EGO18896.1 - 8.4e-61 205.5 0.0 1.4e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO18896.1 - 1e-49 169.1 0.2 1.6e-49 168.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain RNA_pol_Rpb4 PF03874.11 EGO18897.1 - 0.041 13.8 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 Retrotrans_gag PF03732.12 EGO18899.1 - 3.3e-08 33.4 0.0 7.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO18899.1 - 2e-05 24.2 3.6 4e-05 23.3 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO18899.1 - 0.0036 16.7 0.1 0.0061 15.9 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus UL55 protein Metalloenzyme PF01676.13 EGO18900.1 - 6.7e-74 248.4 0.0 1.1e-73 247.7 0.0 1.3 1 1 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EGO18900.1 - 8e-69 231.3 0.1 1.2e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EGO18900.1 - 2e-06 27.4 0.0 4.9e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGO18900.1 - 0.0016 17.6 0.2 0.028 13.6 0.1 2.7 2 1 0 2 2 2 1 Sulfatase WD40 PF00400.27 EGO18901.1 - 8.4e-145 466.1 50.6 7.6e-13 47.8 0.1 13.3 13 0 0 13 13 13 12 WD domain, G-beta repeat PD40 PF07676.7 EGO18901.1 - 1e-19 69.7 10.2 0.65 9.7 0.0 12.2 12 0 0 12 12 12 4 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EGO18901.1 - 5.1e-17 62.2 0.3 0.0023 17.6 0.0 4.8 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EGO18901.1 - 1.6e-14 52.8 10.3 0.73 9.2 0.0 11.8 12 0 0 12 12 12 2 Proteasome subunit A N-terminal signature NACHT PF05729.7 EGO18901.1 - 1.2e-10 41.3 0.0 3.2e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.1 EGO18901.1 - 8.7e-10 38.1 11.4 0.031 13.3 0.0 7.6 2 1 4 7 7 7 3 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EGO18901.1 - 5.2e-08 32.0 12.4 0.1 11.3 3.4 5.4 1 1 3 4 4 4 4 Nup133 N terminal like Peptidase_S9_N PF02897.10 EGO18901.1 - 4.4e-05 22.2 2.6 7.6 4.9 0.0 6.5 5 3 3 9 9 9 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.1 EGO18901.1 - 5.9e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EGO18901.1 - 0.00018 20.4 0.0 0.0021 16.9 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EGO18901.1 - 0.00036 20.6 0.0 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO18901.1 - 0.012 15.7 0.0 0.1 12.7 0.0 2.6 3 0 0 3 3 3 0 RNA helicase AAA PF00004.24 EGO18901.1 - 0.022 14.9 0.1 0.21 11.7 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EGO18901.1 - 0.025 13.4 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CelD_N PF02927.9 EGO18901.1 - 0.036 14.3 0.0 19 5.5 0.0 4.7 5 1 0 5 5 5 0 N-terminal ig-like domain of cellulase DUF2075 PF09848.4 EGO18901.1 - 0.039 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TruB_C PF09142.6 EGO18901.1 - 0.054 13.1 0.2 44 3.8 0.0 5.1 7 0 0 7 7 6 0 tRNA Pseudouridine synthase II, C terminal APS_kinase PF01583.15 EGO18901.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase p450 PF00067.17 EGO18903.1 - 2.3e-49 168.1 0.0 2.8e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M4_C PF02868.10 EGO18903.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Aldo_ket_red PF00248.16 EGO18905.1 - 1e-63 214.8 0.0 1.2e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EGO18906.1 - 2.8e-68 229.8 0.0 3.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LEP503 PF15221.1 EGO18906.1 - 0.18 11.5 0.2 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 Adap_comp_sub PF00928.16 EGO18907.1 - 4e-22 78.5 0.0 5.6e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO18907.1 - 1.1e-08 34.8 0.1 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ubiquitin PF00240.18 EGO18909.1 - 2.7e-35 119.5 0.5 3e-35 119.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGO18909.1 - 1.3e-19 69.6 0.5 1.4e-19 69.4 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO18909.1 - 7.4e-06 26.1 0.1 2.9e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGO18909.1 - 6.3e-05 22.7 0.0 7.2e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGO18909.1 - 0.0026 17.6 0.1 0.006 16.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO18909.1 - 0.012 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGO18909.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EGO18909.1 - 0.24 9.6 0.7 3.2 5.9 0.2 1.9 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EGO18909.1 - 0.34 10.8 1.8 0.62 10.0 1.2 1.3 1 0 0 1 1 1 0 Tash protein PEST motif GPI-anchored PF10342.4 EGO18911.1 - 3.3e-08 33.8 1.9 3.3e-08 33.8 1.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2702 PF10863.3 EGO18911.1 - 0.039 13.6 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) Mucin PF01456.12 EGO18911.1 - 6.5 6.5 29.4 0.22 11.3 11.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_M76 PF09768.4 EGO18912.1 - 1.3e-69 233.0 2.7 1.7e-69 232.7 1.9 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EGO18912.1 - 0.15 11.6 3.1 0.18 11.4 1.5 1.5 1 1 0 1 1 1 0 SprT-like family OmdA PF13376.1 EGO18913.1 - 0.0095 15.5 1.5 0.0098 15.5 1.0 1.2 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated BCNT PF07572.7 EGO18913.1 - 0.5 10.3 4.2 0.54 10.2 2.9 1.1 1 0 0 1 1 1 0 Bucentaur or craniofacial development ECH PF00378.15 EGO18914.1 - 3e-40 137.8 0.1 5.4e-40 137.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TPX2 PF06886.6 EGO18916.1 - 9.4e-11 41.6 27.4 1.9e-10 40.6 14.7 2.3 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) DUF1204 PF06721.6 EGO18916.1 - 0.005 16.1 4.5 0.0068 15.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1204) Pox_G5 PF04599.7 EGO18916.1 - 0.05 12.2 2.8 0.061 12.0 2.0 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Rho_Binding PF08912.6 EGO18916.1 - 0.58 10.4 12.6 0.15 12.3 6.5 1.7 2 0 0 2 2 2 0 Rho Binding Endonuc_Holl PF10107.4 EGO18916.1 - 2 8.0 9.0 4.3 7.0 6.1 1.6 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase AAA_23 PF13476.1 EGO18916.1 - 5.2 7.3 6.4 5.8 7.1 4.4 1.1 1 0 0 1 1 1 0 AAA domain Mso1_C PF14477.1 EGO18917.1 - 0.083 13.2 1.9 0.13 12.6 0.1 2.1 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 NUDIX PF00293.23 EGO18920.1 - 5e-16 58.5 0.1 7.5e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NIF3 PF01784.13 EGO18921.1 - 1.2e-49 169.1 0.0 1.4e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ETF PF01012.16 EGO18921.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Glutaredoxin PF00462.19 EGO18922.1 - 3.9e-17 61.9 0.0 5.6e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EGO18922.1 - 0.021 15.0 0.0 0.12 12.6 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EGO18922.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin CSTF2_hinge PF14327.1 EGO18923.1 - 6.8e-09 35.6 3.4 6.8e-09 35.6 2.4 2.0 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EGO18923.1 - 1.8e-07 30.3 1.4 5.7e-07 28.7 1.0 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Spc7 PF08317.6 EGO18924.1 - 2.8e-13 49.2 9.1 3.6e-13 48.8 6.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EGO18924.1 - 6.7e-06 25.6 0.2 2.4e-05 23.8 0.2 2.0 1 1 0 1 1 1 1 Spc7_C2 Filament PF00038.16 EGO18924.1 - 0.00049 19.6 10.0 0.00059 19.4 6.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF1409 PF07197.7 EGO18924.1 - 0.014 15.4 3.1 0.25 11.4 0.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) HrpB7 PF09486.5 EGO18924.1 - 0.072 13.0 3.2 0.11 12.4 1.8 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 EGO18924.1 - 0.074 12.2 0.9 0.12 11.5 0.6 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TcdA_TcdB PF12919.2 EGO18924.1 - 0.084 11.3 4.1 0.12 10.8 2.9 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cob_adeno_trans PF01923.13 EGO18924.1 - 0.15 11.8 5.4 0.49 10.1 0.1 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Atg14 PF10186.4 EGO18924.1 - 0.15 10.9 8.6 0.24 10.3 6.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cortex-I_coil PF09304.5 EGO18924.1 - 0.21 11.6 12.0 0.17 11.9 0.7 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil CENP-Q PF13094.1 EGO18924.1 - 0.25 11.3 10.1 0.45 10.5 7.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_C6 PF00851.13 EGO18924.1 - 0.33 9.5 3.9 0.55 8.8 2.7 1.3 1 0 0 1 1 1 0 Helper component proteinase IncA PF04156.9 EGO18924.1 - 4.1 6.9 15.6 6.9 6.2 10.8 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EGO18924.1 - 5.5 5.9 10.9 7.5 5.4 7.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EGO18924.1 - 7.5 4.8 6.9 9.9 4.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Retrotrans_gag PF03732.12 EGO18925.1 - 6.3e-06 26.1 2.7 6.3e-06 26.1 1.8 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein RecX PF02631.11 EGO18925.1 - 0.083 13.1 1.8 0.17 12.0 1.1 1.6 1 1 0 1 1 1 0 RecX family Tetraspannin PF00335.15 EGO18926.1 - 2.2e-13 50.0 11.6 2.9e-13 49.6 8.0 1.1 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.9 EGO18926.1 - 0.014 14.3 0.1 0.025 13.5 0.1 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family DUF3278 PF11683.3 EGO18926.1 - 0.03 14.3 0.1 0.075 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) O-antigen_lig PF13425.1 EGO18926.1 - 0.3 11.0 6.0 0.19 11.7 0.4 2.5 3 0 0 3 3 3 0 O-antigen ligase like membrane protein Myb_DNA-bind_4 PF13837.1 EGO18929.1 - 5.3e-05 23.2 0.0 0.00049 20.1 0.0 2.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EGO18929.1 - 0.00011 22.8 0.0 0.00036 21.0 0.0 2.0 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain TT_ORF2 PF02957.10 EGO18929.1 - 0.062 14.0 1.0 0.16 12.6 0.7 1.7 1 0 0 1 1 1 0 TT viral ORF2 Retrotrans_gag PF03732.12 EGO18930.1 - 2.4e-05 24.3 2.5 0.034 14.2 0.0 2.7 1 1 2 3 3 3 2 Retrotransposon gag protein Asp_protease_2 PF13650.1 EGO18930.1 - 0.00072 19.9 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO18930.1 - 0.003 17.3 0.5 0.0074 16.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO18930.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease FlxA PF14282.1 EGO18930.1 - 0.17 11.8 0.5 0.34 10.8 0.4 1.4 1 0 0 1 1 1 0 FlxA-like protein DDE_3 PF13358.1 EGO18931.1 - 3.4e-10 39.8 0.0 5e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease Chitin_synth_2 PF03142.10 EGO18932.1 - 1e-70 238.6 1.6 3.2e-69 233.7 0.7 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO18932.1 - 8.7e-05 22.3 0.1 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO18932.1 - 0.012 15.4 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 TMC PF07810.8 EGO18935.1 - 0.084 13.3 4.2 0.083 13.3 0.4 2.3 2 0 0 2 2 2 0 TMC domain GntR PF00392.16 EGO18936.1 - 0.056 12.8 0.0 13 5.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF3564 PF12087.3 EGO18936.1 - 0.087 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) Cohesin_load PF10345.4 EGO18936.1 - 7.2 4.6 9.4 1.3 7.1 0.7 2.5 2 1 1 3 3 3 0 Cohesin loading factor 2OG-FeII_Oxy PF03171.15 EGO18938.1 - 8.1e-14 51.7 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO18938.1 - 1.5e-13 51.3 0.0 2.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO18939.1 - 1e-12 48.2 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO18939.1 - 2.3e-11 44.2 0.0 3.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DIOX_N PF14226.1 EGO18940.1 - 3.5e-15 56.5 0.0 5.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO18940.1 - 9.1e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DLH PF01738.13 EGO18942.1 - 3.8e-28 98.2 0.0 4.4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO18942.1 - 2.4e-08 33.8 0.0 3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO18942.1 - 4.7e-05 23.3 0.0 0.0049 16.7 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO18942.1 - 0.0041 16.3 0.0 0.02 14.0 0.0 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGO18942.1 - 0.026 14.0 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1649 PF07855.7 EGO18943.1 - 3.4e-32 111.3 0.1 3.9e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) ubiquitin PF00240.18 EGO18944.1 - 2.4e-12 46.0 0.6 4.5e-12 45.1 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGO18944.1 - 1.5e-10 40.6 0.0 6.1e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EGO18944.1 - 1e-06 28.3 0.9 1.7e-06 27.6 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO18944.1 - 0.001 19.2 0.1 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain XPC-binding PF09280.6 EGO18944.1 - 0.018 14.4 10.9 0.022 14.2 5.2 2.8 2 1 0 2 2 2 0 XPC-binding domain Ubiquitin_2 PF14560.1 EGO18944.1 - 0.1 12.8 0.4 0.2 11.9 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DLH PF01738.13 EGO18945.1 - 2.3e-26 92.4 0.4 2.6e-26 92.2 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO18945.1 - 7.5e-10 38.7 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO18945.1 - 9.5e-05 22.3 0.1 0.13 12.0 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO18945.1 - 0.03 13.5 0.0 0.081 12.1 0.0 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGO18945.1 - 0.1 12.1 0.0 3 7.3 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Antimicrobial_1 PF08018.6 EGO18946.1 - 0.021 14.7 0.1 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide SNF2_N PF00176.18 EGO18947.1 - 4.2e-76 255.6 0.3 8.2e-76 254.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGO18947.1 - 2.6e-40 136.8 0.3 2.6e-40 136.8 0.2 3.1 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 EGO18947.1 - 3.7e-27 94.9 2.8 3.7e-27 94.9 2.0 3.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EGO18947.1 - 2.5e-14 52.9 0.0 1e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO18947.1 - 1.5e-07 31.4 0.2 4.8e-06 26.5 0.0 3.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO18947.1 - 1.3e-05 24.7 0.0 3.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.1 EGO18947.1 - 0.00069 19.6 5.3 0.00069 19.6 3.7 4.8 4 0 0 4 4 4 2 DNA-binding domain AAA_14 PF13173.1 EGO18947.1 - 0.0035 17.2 0.7 0.021 14.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain EI24 PF07264.6 EGO18948.1 - 0.00031 20.2 8.4 0.0012 18.2 5.8 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Caa3_CtaG PF09678.5 EGO18948.1 - 0.067 12.1 1.9 0.09 11.6 0.3 1.9 2 1 1 3 3 3 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) AhpC-TSA_2 PF13911.1 EGO18949.1 - 9.2e-13 48.1 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGO18949.1 - 1.1e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO18949.1 - 2.6e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Transp_cyt_pur PF02133.10 EGO18950.1 - 2e-25 89.2 30.7 3e-25 88.6 21.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.3 EGO18950.1 - 2.2 7.7 8.5 9.6 5.6 5.9 2.1 1 0 0 1 1 1 0 Conserved membrane protein YqhR Adaptin_N PF01602.15 EGO18951.1 - 1.2e-88 297.7 8.1 1.7e-88 297.2 5.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EGO18951.1 - 4e-66 220.6 0.2 1.3e-65 218.9 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EGO18951.1 - 5.6e-58 194.5 0.0 2e-57 192.7 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EGO18951.1 - 1.2e-12 47.9 0.1 0.00064 19.9 0.0 5.2 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EGO18951.1 - 2.3e-06 27.2 0.1 0.082 13.0 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGO18951.1 - 2.9e-05 23.9 8.0 0.58 9.9 0.6 5.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EGO18951.1 - 0.003 17.4 0.9 0.27 11.1 0.0 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein Arm_2 PF04826.8 EGO18951.1 - 0.004 16.3 1.6 0.48 9.4 0.7 2.9 2 1 1 3 3 3 2 Armadillo-like HEAT_EZ PF13513.1 EGO18951.1 - 0.037 14.5 0.1 8.1 7.0 0.0 4.7 5 1 0 5 5 5 0 HEAT-like repeat PepSY_TM_1 PF13172.1 EGO18954.1 - 5.2 6.9 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO18955.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO18955.1 - 0.014 15.0 0.4 0.021 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO18955.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Myc_N PF01056.13 EGO18957.1 - 0.047 12.8 0.2 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region GPW_gp25 PF04965.9 EGO18957.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Gene 25-like lysozyme Nop10p PF04135.7 EGO18959.1 - 1.9e-20 72.2 0.5 2.2e-20 72.0 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CRAL_TRIO PF00650.15 EGO18960.1 - 2.5e-39 134.3 0.0 3.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EGO18960.1 - 2.7e-06 27.3 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO18960.1 - 0.017 15.2 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain SpoVAD PF07451.6 EGO18963.1 - 0.048 12.1 0.0 0.084 11.3 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) CDC45 PF02724.9 EGO18963.1 - 0.18 9.8 1.7 0.21 9.6 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Collagen PF01391.13 EGO18963.1 - 0.42 10.1 5.1 0.78 9.3 3.5 1.4 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) TFIIA PF03153.8 EGO18964.1 - 0.076 12.8 2.8 0.076 12.8 2.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 EGO18967.1 - 1.3e-07 31.3 7.6 1.3e-07 31.3 5.3 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGO18967.1 - 7e-06 25.6 8.6 7e-06 25.6 6.0 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO18967.1 - 8e-05 22.5 8.2 8e-05 22.5 5.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO18967.1 - 0.00043 19.9 6.7 0.00043 19.9 4.6 2.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO18967.1 - 0.014 15.1 3.4 0.014 15.1 2.4 2.0 2 0 0 2 2 2 0 RING-type zinc-finger DivIC PF04977.10 EGO18967.1 - 0.038 13.4 1.8 0.084 12.3 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 EGO18967.1 - 0.043 14.1 0.5 0.043 14.1 0.4 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF972) HCMV_UL139 PF12507.3 EGO18967.1 - 0.053 13.6 0.3 0.053 13.6 0.2 1.9 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF904 PF06005.7 EGO18967.1 - 2.1 8.7 11.9 0.15 12.3 3.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) zf-RING_6 PF14835.1 EGO18967.1 - 5 6.9 10.1 3.8 7.3 2.0 2.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein HypA PF01155.14 EGO18967.1 - 5.2 6.7 11.3 3.3 7.4 0.9 3.0 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family PRP1_N PF06424.7 EGO18968.1 - 0.34 11.2 3.0 0.32 11.3 1.3 1.5 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal CENP-F_leu_zip PF10473.4 EGO18969.1 - 0.021 14.6 0.6 0.025 14.4 0.4 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliG_C PF01706.11 EGO18969.1 - 0.094 12.6 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 FliG C-terminal domain RHD3 PF05879.7 EGO18970.1 - 1.1e-08 33.5 0.1 1.1e-08 33.5 0.1 1.7 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EGO18970.1 - 7.3e-07 28.5 0.1 1.6e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain VWA_2 PF13519.1 EGO18972.1 - 2.3e-09 37.6 0.5 3.1e-09 37.1 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO18972.1 - 1.4e-06 28.1 0.2 2.6e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EGO18972.1 - 0.0039 16.3 0.3 0.14 11.2 0.1 2.1 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein Enolase_C PF00113.17 EGO18973.1 - 6.1e-146 485.0 0.1 8.5e-146 484.5 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGO18973.1 - 2.5e-58 195.7 0.2 4.1e-58 195.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EGO18973.1 - 6.6e-06 26.0 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EGO18973.1 - 0.00048 19.1 0.4 0.00097 18.1 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EGO18973.1 - 0.023 15.2 0.0 0.049 14.1 0.0 1.6 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain PAN_4 PF14295.1 EGO18974.1 - 0.044 13.4 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 EGO18974.1 - 0.096 12.3 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 PAN-like domain ADH_zinc_N PF00107.21 EGO18975.1 - 2.6e-13 49.6 0.0 5.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO18975.1 - 4.4e-06 26.4 1.8 0.00075 19.2 0.8 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EGO18976.1 - 2.3e-12 46.2 50.3 3.4e-08 32.5 21.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily NGP1NT PF08153.7 EGO18977.1 - 8.1e-45 151.9 0.0 2e-44 150.6 0.0 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EGO18977.1 - 7.6e-20 71.0 0.0 6.7e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO18977.1 - 1.5e-05 24.3 0.1 0.00016 21.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGO18977.1 - 0.00019 20.8 0.3 0.039 13.3 0.1 2.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGO18977.1 - 0.00028 20.1 0.0 0.00055 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO18977.1 - 0.0045 16.8 0.6 3.1 7.5 0.1 3.7 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 EGO18977.1 - 0.016 14.4 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Actino_peptide PF14408.1 EGO18977.1 - 0.021 14.7 0.7 0.052 13.4 0.5 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Rhabdo_ncap PF00945.13 EGO18977.1 - 0.4 9.2 2.1 0.68 8.4 1.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Ribosomal_S15 PF00312.17 EGO18978.1 - 5.7e-19 67.6 0.1 1.2e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 RGCC PF15151.1 EGO18980.1 - 0.08 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Response gene to complement 32 protein family Sec34 PF04136.10 EGO18980.1 - 0.08 12.6 0.4 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Sec34-like family FTA4 PF13093.1 EGO18980.1 - 0.25 10.7 3.7 0.94 8.8 2.6 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CAS_CSE1 PF03378.10 EGO18981.1 - 2e-05 23.1 0.1 0.00017 20.0 0.0 2.4 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EGO18981.1 - 5.1e-05 23.1 0.0 0.0024 17.7 0.0 3.4 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGO18981.1 - 0.00032 20.9 1.5 0.023 14.9 0.0 3.8 3 2 0 3 3 3 1 HEAT repeats ParcG PF10274.4 EGO18981.1 - 0.00038 20.4 0.1 2.3 8.1 0.0 3.2 3 0 0 3 3 3 2 Parkin co-regulated protein RIX1 PF08167.7 EGO18981.1 - 0.00077 19.1 3.1 0.014 15.1 0.1 3.6 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 EGO18981.1 - 0.0031 17.4 1.3 0.026 14.4 0.0 3.3 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EGO18981.1 - 0.0062 16.5 1.5 0.21 11.7 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGO18981.1 - 0.0098 15.7 0.1 0.098 12.5 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGO18981.1 - 0.012 13.9 0.7 0.041 12.2 0.1 2.1 3 0 0 3 3 3 0 Adaptin N terminal region Peptidase_S64 PF08192.6 EGO18984.1 - 0.34 9.1 8.1 0.53 8.5 5.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 GSH-S_N PF02951.9 EGO18988.1 - 0.028 14.2 0.1 0.039 13.7 0.1 1.3 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain I_LWEQ PF01608.12 EGO18988.1 - 0.075 12.9 0.7 0.095 12.6 0.5 1.1 1 0 0 1 1 1 0 I/LWEQ domain Takusan PF04822.8 EGO18988.1 - 0.14 11.9 2.9 0.18 11.5 1.2 1.8 2 0 0 2 2 2 0 Takusan Anthrax_toxA PF03497.11 EGO18990.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Anthrax toxin LF subunit DUF4355 PF14265.1 EGO18992.1 - 0.083 12.8 1.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Histone_HNS PF00816.16 EGO18992.1 - 0.21 12.0 1.6 0.3 11.6 0.2 1.9 2 0 0 2 2 2 0 H-NS histone family NAD_binding_6 PF08030.7 EGO18998.1 - 1e-23 83.9 0.0 1.9e-23 83.0 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO18998.1 - 7.9e-23 80.3 0.0 2.2e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGO18998.1 - 1.8e-15 57.0 10.6 1.8e-15 57.0 7.3 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGO18998.1 - 0.0011 19.0 0.0 0.0033 17.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO18998.1 - 0.0016 19.0 0.0 0.097 13.2 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Methyltransf_16 PF10294.4 EGO18999.1 - 1.5e-16 60.3 0.0 2.7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO18999.1 - 4.3e-06 27.2 0.0 1.1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO18999.1 - 8.5e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO18999.1 - 8.4e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO18999.1 - 0.0002 21.3 0.0 0.00054 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EGO18999.1 - 0.0024 17.4 0.0 0.007 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EGO18999.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGO18999.1 - 0.037 13.3 0.1 0.2 11.0 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EGO18999.1 - 0.046 12.8 0.1 0.32 10.0 0.1 2.0 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_18 PF00704.23 EGO19000.1 - 1.4e-90 304.1 12.8 1.6e-90 304.0 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Homeobox PF00046.24 EGO19002.1 - 8.2e-09 34.9 0.4 1.6e-08 34.0 0.3 1.5 1 0 0 1 1 1 1 Homeobox domain PGA2 PF07543.7 EGO19002.1 - 1.1 9.0 6.8 0.57 9.9 2.8 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 gag_pre-integrs PF13976.1 EGO19004.1 - 4.5e-09 35.8 0.0 7.2e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain HK97-gp10_like PF04883.7 EGO19005.1 - 0.15 12.9 1.0 0.16 12.8 0.7 1.1 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component PepSY_TM_1 PF13172.1 EGO19006.1 - 5.2 6.9 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix DDE_1 PF03184.14 EGO19009.1 - 8e-24 83.9 0.0 1.1e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO19009.1 - 0.00029 20.6 0.0 0.0013 18.5 0.0 1.9 2 1 0 2 2 2 1 DDE superfamily endonuclease p450 PF00067.17 EGO19010.1 - 4.9e-55 186.8 0.0 5.9e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EGO19011.1 - 4.6e-26 91.3 33.1 8.1e-26 90.5 22.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO19011.1 - 5.2e-08 31.5 1.1 5.2e-08 31.5 0.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO19011.1 - 0.45 8.8 32.2 0.059 11.7 1.2 2.7 2 1 1 3 3 3 0 MFS/sugar transport protein CarboxypepD_reg PF13620.1 EGO19017.1 - 0.065 13.2 0.6 0.42 10.6 0.1 2.3 1 1 1 2 2 2 0 Carboxypeptidase regulatory-like domain MFS_1 PF07690.11 EGO19019.1 - 5.3e-28 97.7 32.4 8.2e-28 97.1 22.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO19019.1 - 3.4e-08 32.1 5.7 3.8e-08 32.0 1.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO19019.1 - 0.33 9.2 33.6 0.09 11.1 1.3 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein DUF3817 PF12823.2 EGO19019.1 - 2.3 8.7 10.3 0.24 11.8 3.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) Lyase_aromatic PF00221.14 EGO19020.1 - 7.4e-146 486.3 1.0 9.1e-146 486.0 0.7 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Thioredoxin PF00085.15 EGO19021.1 - 2.1e-19 69.1 0.0 2.3e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EGO19021.1 - 0.0002 21.0 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EGO19021.1 - 0.00048 20.2 0.0 0.0064 16.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGO19021.1 - 0.00048 20.0 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EGO19021.1 - 0.00072 19.6 0.0 0.005 16.9 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EGO19021.1 - 0.035 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Mating_N PF12731.2 EGO19021.1 - 0.073 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein beta 1 Redoxin PF08534.5 EGO19021.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Redoxin E1_dh PF00676.15 EGO19022.1 - 0.0047 15.6 0.0 0.0047 15.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Adaptin_N PF01602.15 EGO19024.1 - 6.2e-112 374.5 7.2 8.8e-112 374.0 5.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGO19024.1 - 1.1e-07 31.9 3.8 0.18 12.1 0.0 5.3 3 3 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EGO19024.1 - 1.4e-05 24.9 3.2 0.1 12.4 0.0 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGO19024.1 - 0.00047 20.0 1.4 12 6.3 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat DUF2435 PF10363.4 EGO19024.1 - 0.001 18.9 2.0 0.48 10.3 0.3 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Nipped-B_C PF12830.2 EGO19024.1 - 0.032 13.8 1.9 6.6 6.3 0.0 3.5 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.1 EGO19024.1 - 0.083 13.4 5.3 5.5 7.6 0.0 5.5 6 1 1 7 7 7 0 HEAT-like repeat Flt3_lig PF02947.9 EGO19024.1 - 0.097 12.5 0.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 flt3 ligand Arm PF00514.18 EGO19024.1 - 2 8.3 6.9 26 4.8 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cation_efflux PF01545.16 EGO19027.1 - 2.4e-31 108.8 6.5 3e-31 108.5 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family Pap_E4 PF02711.9 EGO19028.1 - 0.1 13.4 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 E4 protein HsbA PF12296.3 EGO19029.1 - 0.13 12.1 0.0 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Zip PF02535.17 EGO19029.1 - 1.4 7.8 7.9 1.9 7.4 5.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter F5_F8_type_C PF00754.20 EGO19033.1 - 2.9e-06 27.1 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 EGO19033.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Y_phosphatase PF00102.22 EGO19034.1 - 9.6e-39 133.1 0.0 1.9e-21 76.4 0.0 3.0 3 0 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGO19034.1 - 0.0005 20.1 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGO19034.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EGO19034.1 - 0.17 11.4 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ADH_zinc_N PF00107.21 EGO19035.1 - 1.4e-32 111.9 0.1 6.4e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO19035.1 - 3.5e-13 50.5 0.2 8.6e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO19035.1 - 2.9e-07 30.1 0.0 1.3e-06 28.0 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 EGO19035.1 - 0.0092 15.6 0.3 0.0092 15.6 0.2 1.8 2 0 0 2 2 2 1 SIS domain TrkA_N PF02254.13 EGO19035.1 - 0.044 13.7 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh PF00389.25 EGO19035.1 - 0.052 13.0 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cerato-platanin PF07249.7 EGO19040.1 - 0.013 15.5 0.8 0.39 10.7 0.1 2.2 1 1 1 2 2 2 0 Cerato-platanin HTH_psq PF05225.11 EGO19041.1 - 4.9e-05 22.7 0.4 0.00011 21.7 0.3 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EGO19041.1 - 0.0067 15.5 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EGO19041.1 - 0.047 13.7 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Retrotrans_gag PF03732.12 EGO19042.1 - 1.3e-07 31.5 0.0 3.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO19042.1 - 3.8e-07 29.7 1.3 9.5e-07 28.4 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO19042.1 - 0.32 10.7 3.9 0.73 9.6 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO19042.1 - 0.39 10.4 2.4 0.83 9.3 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.2 EGO19043.1 - 0.0047 16.6 0.2 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO19043.1 - 0.009 15.6 0.2 0.02 14.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain CoA_binding_3 PF13727.1 EGO19043.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain DUF4381 PF14316.1 EGO19047.1 - 0.049 13.7 0.3 0.053 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) tRNA-synt_His PF13393.1 EGO19048.1 - 1e-39 136.4 0.0 1.6e-34 119.4 0.0 3.0 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGO19048.1 - 8.5e-17 61.2 0.0 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO19048.1 - 2.1e-08 33.9 0.0 4.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 EGO19048.1 - 0.0047 16.5 6.3 0.0047 16.5 4.4 2.4 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2d PF01409.15 EGO19048.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EGO19048.1 - 0.17 10.6 0.0 2.4 6.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) HHH_8 PF14716.1 EGO19048.1 - 0.76 10.0 5.6 0.89 9.7 0.0 3.5 4 1 1 5 5 5 0 Helix-hairpin-helix domain CDP-OH_P_transf PF01066.16 EGO19049.1 - 3.1e-16 59.5 3.2 3.1e-16 59.5 2.2 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Fungal_trans PF04082.13 EGO19050.1 - 1.4e-11 43.8 0.2 2.6e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EGO19051.1 - 1.9e-73 246.7 0.0 2.6e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19051.1 - 7.1e-39 133.4 0.0 1e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EGO19051.1 - 9.6e-07 28.8 0.1 9.6e-07 28.8 0.1 2.1 3 0 0 3 3 3 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EGO19051.1 - 4e-06 25.9 0.0 6.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGO19051.1 - 0.00029 20.2 0.1 0.00049 19.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGO19051.1 - 0.011 15.4 0.6 0.12 12.0 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO19051.1 - 0.033 13.2 0.3 0.11 11.5 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4381 PF14316.1 EGO19056.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) BTB PF00651.26 EGO19057.1 - 0.088 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Retrotrans_gag PF03732.12 EGO19059.1 - 1.2e-07 31.6 0.4 1.2e-07 31.6 0.3 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO19059.1 - 7.9e-07 28.7 1.9 1.4e-06 27.9 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle BMFP PF04380.8 EGO19059.1 - 0.037 14.1 1.4 4.5 7.4 0.2 3.5 3 0 0 3 3 3 0 Membrane fusogenic activity p450 PF00067.17 EGO19060.1 - 4.3e-75 253.0 0.0 5.4e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EGO19061.1 - 1.5e-29 103.5 0.1 1.7e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19061.1 - 5.2e-15 55.6 0.0 2.5e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO19061.1 - 4.7e-11 42.6 0.0 1.6e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO19061.1 - 6.4e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 EGO19061.1 - 0.023 13.5 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) MFS_1 PF07690.11 EGO19062.1 - 1.9e-26 92.6 49.9 1.2e-14 53.8 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO19062.1 - 9.8e-06 24.3 7.8 9.8e-06 24.3 5.4 2.8 1 1 2 3 3 3 1 Sugar (and other) transporter Peptidase_M17 PF00883.16 EGO19063.1 - 7.8e-115 383.0 0.0 9.6e-115 382.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EGO19063.1 - 4.5e-07 29.6 0.0 9.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF429 PF04250.8 EGO19063.1 - 0.035 13.3 0.1 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) AlaDh_PNT_N PF05222.10 EGO19066.1 - 1.1e-26 93.4 0.0 1.7e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGO19066.1 - 3.1e-14 52.9 0.0 5.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1900 PF08954.6 EGO19066.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Glyco_hydro_28 PF00295.12 EGO19068.1 - 4.6e-35 121.1 0.9 8e-35 120.3 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EGO19068.1 - 2.1 8.0 16.2 3.4 7.4 7.2 3.1 2 1 1 3 3 3 0 Right handed beta helix region Histone PF00125.19 EGO19069.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO19069.1 - 1.4e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO19069.1 - 0.0012 18.8 1.9 0.0014 18.6 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO19069.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGO19069.1 - 0.19 10.9 1.9 0.21 10.7 1.4 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T EthD PF07110.6 EGO19071.1 - 2.3e-11 44.4 0.1 2.6e-11 44.3 0.1 1.0 1 0 0 1 1 1 1 EthD domain Glucosamine_iso PF01182.15 EGO19072.1 - 1.5e-64 217.4 0.0 1.7e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase S6PP PF05116.8 EGO19073.1 - 0.014 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Ribosomal_L2_C PF03947.13 EGO19074.1 - 4e-50 168.9 0.2 6.7e-50 168.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGO19074.1 - 7.6e-26 89.8 0.1 1.3e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TIP49 PF06068.8 EGO19075.1 - 4.7e-178 591.9 2.4 5.8e-178 591.6 1.7 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGO19075.1 - 5.2e-09 36.4 0.5 9.4e-06 25.8 0.0 2.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO19075.1 - 3e-07 29.7 2.0 0.0014 17.7 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EGO19075.1 - 1e-05 24.6 0.2 1.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 EGO19075.1 - 0.00024 20.5 0.1 0.00053 19.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO19075.1 - 0.00041 20.4 0.1 0.0024 17.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO19075.1 - 0.0011 19.1 0.1 0.31 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGO19075.1 - 0.013 14.7 3.5 0.17 11.0 0.2 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO19075.1 - 0.034 13.8 0.9 12 5.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EGO19075.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit HSBP1 PF06825.7 EGO19077.1 - 0.011 15.2 0.4 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Pheromone PF08015.6 EGO19077.1 - 7.8 7.4 11.3 6.3 7.7 0.0 3.7 4 1 0 4 4 4 0 Fungal mating-type pheromone MRP-L46 PF11788.3 EGO19081.1 - 0.52 10.9 3.2 1.2 9.7 2.2 1.7 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Thioredoxin PF00085.15 EGO19085.1 - 2.1e-29 101.2 0.0 2.3e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGO19085.1 - 4.1e-08 33.4 0.2 2.9e-07 30.6 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGO19085.1 - 8.9e-07 28.6 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGO19085.1 - 1.5e-06 28.2 0.1 3.2e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EGO19085.1 - 8e-06 25.4 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EGO19085.1 - 0.0011 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EGO19085.1 - 0.0013 18.2 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EGO19085.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin LytTR PF04397.10 EGO19086.1 - 0.12 12.5 0.7 0.13 12.3 0.5 1.1 1 0 0 1 1 1 0 LytTr DNA-binding domain Pkinase PF00069.20 EGO19088.1 - 7.3e-59 199.0 0.0 1.1e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19088.1 - 2.4e-25 89.1 0.0 1.9e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGO19088.1 - 0.00089 19.7 10.2 0.00089 19.7 7.1 3.2 2 1 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 EGO19088.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO19088.1 - 0.027 13.4 0.0 0.43 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EGO19088.1 - 0.04 13.6 0.5 3.5 7.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family PX PF00787.19 EGO19088.1 - 0.056 13.2 0.0 0.26 11.1 0.0 2.1 1 1 0 1 1 1 0 PX domain Hs1pro-1_C PF07014.7 EGO19088.1 - 0.28 10.4 0.0 0.46 9.7 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Pyridox_oxase_2 PF12766.2 EGO19090.1 - 3.6e-25 88.1 0.1 7.2e-25 87.2 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EGO19090.1 - 3.1e-06 27.0 0.0 1.4e-05 24.9 0.0 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CorA PF01544.13 EGO19091.1 - 2.4e-34 118.7 8.1 2.7e-31 108.7 4.8 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein HAD_2 PF13419.1 EGO19092.1 - 1.4e-24 87.3 0.1 2.5e-24 86.4 0.1 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO19092.1 - 3.6e-06 26.5 0.0 6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO19092.1 - 9.4e-06 26.1 0.1 0.00027 21.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 EGO19093.1 - 6.6e-48 162.4 0.0 2.2e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGO19093.1 - 1.4e-23 83.5 46.4 2.7e-12 46.4 20.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGO19093.1 - 2e-21 77.2 1.0 4.7e-07 30.0 0.0 4.4 3 1 0 4 4 4 4 AAA domain AAA_23 PF13476.1 EGO19093.1 - 1.5e-06 28.6 2.0 0.042 14.1 0.2 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGO19093.1 - 3.2e-05 23.2 2.4 0.11 11.6 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGO19093.1 - 5.5e-05 22.6 1.9 0.098 12.1 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGO19093.1 - 0.0047 16.1 0.2 3.3 6.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EGO19093.1 - 0.27 10.2 0.5 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EGO19093.1 - 0.29 10.7 3.1 8.3 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EGO19093.1 - 0.33 9.9 0.0 24 3.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.17 EGO19093.1 - 0.41 10.0 2.7 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGO19093.1 - 1.8 8.6 4.1 40 4.3 0.2 3.4 4 1 0 4 4 3 0 AAA domain Swi5 PF07061.6 EGO19094.1 - 3.3e-16 58.8 2.9 3.9e-16 58.6 2.0 1.1 1 0 0 1 1 1 1 Swi5 Band_3_cyto PF07565.8 EGO19094.1 - 0.032 13.7 0.1 0.032 13.7 0.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1826 PF08856.6 EGO19094.1 - 0.049 13.3 0.1 0.056 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) Sec2p PF06428.6 EGO19094.1 - 0.076 12.8 1.7 0.11 12.3 0.7 1.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p SOG2 PF10428.4 EGO19094.1 - 0.091 11.4 0.3 0.099 11.2 0.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RCC1 PF00415.13 EGO19095.1 - 1.6e-33 114.6 10.8 1.3e-06 28.4 0.6 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO19095.1 - 1.4e-10 40.5 35.9 0.0017 17.9 0.1 8.1 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Raptor_N PF14538.1 EGO19096.1 - 1.1e-56 191.0 0.0 3.1e-56 189.4 0.0 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EGO19096.1 - 2.6e-12 46.0 9.5 6.4e-06 25.8 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 EGO19096.1 - 5.1e-05 23.0 2.2 0.00049 19.9 0.0 3.6 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EGO19096.1 - 0.00043 20.5 0.0 0.0017 18.5 0.0 2.1 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EGO19096.1 - 0.076 13.5 0.7 0.4 11.2 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat PfkB PF00294.19 EGO19097.1 - 1.2e-67 228.1 0.6 1.4e-67 227.9 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RdRP PF05183.7 EGO19098.1 - 1.5e-93 314.5 0.0 3.4e-93 313.3 0.0 1.5 1 1 1 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EGO19099.1 - 2.8e-24 84.5 0.2 6.7e-13 48.0 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO19099.1 - 1e-17 63.8 0.0 3.3e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO19099.1 - 6.5e-17 61.1 0.0 2.9e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGO19099.1 - 0.002 17.8 0.1 0.1 12.3 0.0 2.6 2 1 0 2 2 2 1 Limkain b1 Nup153 PF08604.5 EGO19099.1 - 0.016 13.8 0.3 0.024 13.3 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like Malic_M PF03949.10 EGO19100.1 - 8.4e-76 254.8 0.0 1.2e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGO19100.1 - 1e-59 201.1 0.0 1.4e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LysM PF01476.15 EGO19101.1 - 1.3e-15 56.9 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain MARVEL PF01284.18 EGO19102.1 - 2.6e-06 27.3 19.6 3.5e-06 26.8 13.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Bac_export_2 PF01312.14 EGO19102.1 - 5.4 5.7 6.3 3.4 6.4 1.8 1.9 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DUF1602 PF07673.9 EGO19105.1 - 0.1 12.0 0.2 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) HA2 PF04408.18 EGO19106.1 - 1.1e-18 67.0 0.0 2.7e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.20 EGO19106.1 - 5.1e-14 52.5 0.0 3.5e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 EGO19106.1 - 3.1e-12 46.1 0.0 6.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO19106.1 - 3.9e-07 29.7 0.2 8.9e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EGO19106.1 - 1.4e-06 28.1 0.1 5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EGO19106.1 - 0.012 15.7 0.0 0.053 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.18 EGO19107.1 - 5.4e-07 29.2 4.8 1.4e-06 27.9 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO19107.1 - 0.035 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO19107.1 - 0.063 13.0 3.6 0.2 11.4 2.5 1.8 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO19107.1 - 0.082 12.9 3.0 0.39 10.7 0.0 2.7 2 1 0 2 2 2 0 Retrotransposon gag protein Ribosomal_L28e PF01778.12 EGO19108.1 - 4.3e-30 104.4 0.0 5.3e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ribosomal_S4 PF00163.14 EGO19111.1 - 8.4e-27 93.4 0.6 1.7e-26 92.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGO19111.1 - 1.8e-13 49.6 0.6 1.8e-13 49.6 0.4 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EGO19112.1 - 7.4e-37 125.1 5.0 8e-37 125.0 2.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e zf-MYND PF01753.13 EGO19113.1 - 2.8e-08 33.5 11.1 5e-08 32.6 7.7 1.4 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.1 EGO19113.1 - 1.8 7.9 5.2 11 5.3 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain COX5A PF02284.11 EGO19114.1 - 6.2e-40 135.5 0.1 7.6e-40 135.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Cas_Cas02710 PF09670.5 EGO19114.1 - 0.025 13.1 0.4 0.034 12.8 0.2 1.3 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Polysacc_deac_1 PF01522.16 EGO19115.1 - 0.0015 18.1 0.1 0.0053 16.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF1517 PF07466.6 EGO19115.1 - 8.8 5.2 5.9 14 4.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Acetyltransf_1 PF00583.19 EGO19117.1 - 4.1e-07 29.9 0.0 5.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO19117.1 - 0.00023 21.2 0.0 0.00028 20.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO19117.1 - 0.00078 19.2 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EGO19117.1 - 0.00086 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO19117.1 - 0.0025 17.9 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO19117.1 - 0.0071 16.3 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO19117.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein FMN_bind_2 PF04299.7 EGO19122.1 - 7.6e-47 158.9 0.0 8.9e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain p47_phox_C PF08944.6 EGO19125.1 - 0.0055 16.8 0.3 0.0081 16.3 0.2 1.3 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain gag-asp_proteas PF13975.1 EGO19126.1 - 3.7e-09 36.2 0.0 4.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO19126.1 - 9.7e-07 28.7 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO19126.1 - 3.4e-05 24.2 0.0 5.4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO19126.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EGO19127.1 - 0.0086 15.9 0.8 0.014 15.2 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO19127.1 - 0.027 14.5 0.2 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein Gastrin PF00918.12 EGO19127.1 - 0.1 13.4 1.6 0.18 12.6 0.3 2.0 2 1 0 2 2 2 0 Gastrin/cholecystokinin family Retrotrans_gag PF03732.12 EGO19128.1 - 8.4e-08 32.1 0.4 8.4e-08 32.1 0.3 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO19128.1 - 8.6e-07 28.5 4.8 1.6e-06 27.7 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO19128.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO19128.1 - 0.081 12.6 3.4 0.17 11.6 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Chitin_synth_2 PF03142.10 EGO19131.1 - 2.1e-275 914.1 0.0 2.8e-275 913.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO19131.1 - 6.4e-15 55.3 0.4 1.6e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO19131.1 - 5e-10 39.5 0.0 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EGO19131.1 - 4.7e-05 23.1 0.0 0.00083 19.1 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EGO19131.1 - 0.00051 19.3 0.1 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 BTB_2 PF02214.17 EGO19132.1 - 0.00024 21.2 0.0 0.0043 17.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain SUI1 PF01253.17 EGO19133.1 - 1.2e-20 73.0 1.1 2.1e-20 72.3 0.8 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EGO19133.1 - 0.026 14.4 0.5 0.042 13.7 0.3 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Yae1_N PF09811.4 EGO19134.1 - 2.9e-10 39.5 6.3 4.6e-10 38.8 4.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cu_amine_oxid PF01179.15 EGO19135.1 - 3.6e-155 516.7 0.0 4.4e-155 516.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGO19135.1 - 4e-15 55.6 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGO19135.1 - 7.8e-07 29.0 0.2 2.7e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Collagen PF01391.13 EGO19135.1 - 0.062 12.8 1.6 0.12 11.9 1.1 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF3140 PF11338.3 EGO19136.1 - 3.3e-20 72.0 1.2 3.3e-20 72.0 0.9 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) Peptidase_S49_N PF08496.5 EGO19136.1 - 8.7 6.1 11.1 3 7.6 2.9 2.3 1 1 0 2 2 2 0 Peptidase family S49 N-terminal TPR_9 PF13371.1 EGO19137.1 - 0.00086 19.1 2.4 0.0011 18.8 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat NST1 PF13945.1 EGO19137.1 - 0.32 11.0 9.7 1.6 8.7 2.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator zf-C2H2_jaz PF12171.3 EGO19139.1 - 7.3e-19 67.3 43.3 2.7e-05 24.1 1.9 7.7 7 1 1 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGO19139.1 - 2.2e-18 65.3 51.1 0.011 15.9 1.1 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO19139.1 - 1.1e-14 53.6 39.6 0.054 13.8 0.3 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGO19139.1 - 1e-09 38.4 32.8 0.00058 19.9 8.9 5.4 1 1 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGO19139.1 - 2.2e-08 34.0 38.6 0.0033 17.5 2.2 7.3 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EGO19139.1 - 1.3e-05 25.2 39.6 0.72 10.2 0.2 8.4 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGO19139.1 - 0.00021 21.0 35.9 0.19 11.6 0.4 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger Zn_ribbon_2 PF12674.2 EGO19139.1 - 0.0034 17.6 15.0 0.0045 17.3 0.6 3.6 3 1 0 4 4 4 2 Putative zinc ribbon domain DUF4187 PF13821.1 EGO19139.1 - 0.0088 15.6 31.9 0.03 13.8 0.9 5.8 4 2 2 6 6 6 2 Domain of unknown function (DUF4187) zf-H2C2_5 PF13909.1 EGO19139.1 - 0.017 15.3 0.6 0.017 15.3 0.4 6.6 7 1 0 7 7 7 0 C2H2-type zinc-finger domain DZR PF12773.2 EGO19139.1 - 0.055 13.2 18.8 4.1 7.2 8.4 4.2 2 2 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.1 EGO19139.1 - 0.23 10.6 0.1 0.23 10.6 0.0 3.7 4 1 0 4 4 4 0 Transcription factor zinc-finger Ribosomal_L31 PF01197.13 EGO19139.1 - 0.51 10.3 5.7 6.9 6.7 0.1 3.3 3 1 0 3 3 3 0 Ribosomal protein L31 CK_II_beta PF01214.13 EGO19139.1 - 1.9 7.9 16.8 6.4 6.2 0.1 4.1 2 1 2 4 4 4 0 Casein kinase II regulatory subunit Ecl1 PF12855.2 EGO19139.1 - 5 6.4 16.5 4.8 6.5 0.1 4.5 2 1 2 4 4 4 0 Life-span regulatory factor zf-CHCC PF10276.4 EGO19139.1 - 6.6 6.6 12.3 1.2 8.9 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger domain PyrI_C PF02748.10 EGO19139.1 - 8.1 5.9 16.1 3 7.3 1.0 4.2 3 1 2 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain EF-hand_1 PF00036.27 EGO19140.1 - 9.3e-27 90.2 16.9 2.9e-09 35.5 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO19140.1 - 1.2e-24 86.1 14.0 2.6e-12 46.6 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO19140.1 - 6.4e-23 78.5 13.5 1.7e-08 33.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGO19140.1 - 2.5e-15 55.8 18.4 2.6e-09 36.5 1.5 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGO19140.1 - 3.5e-14 51.3 10.5 8.7e-05 21.6 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EGO19140.1 - 7e-11 41.8 1.2 7.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGO19140.1 - 2.6e-08 33.5 8.1 0.00072 19.2 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EGO19140.1 - 0.0017 17.9 0.2 0.034 13.7 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein DUF1636 PF07845.6 EGO19140.1 - 0.028 14.6 0.0 3 8.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) DUF3164 PF11363.3 EGO19140.1 - 0.033 13.6 0.3 1.3 8.3 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3164) SPARC_Ca_bdg PF10591.4 EGO19140.1 - 0.058 13.4 3.1 1.3 9.1 0.1 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Adaptin_binding PF10199.4 EGO19140.1 - 0.067 13.4 0.5 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF1059 PF06348.6 EGO19140.1 - 0.083 12.7 0.2 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) EF-hand_like PF09279.6 EGO19140.1 - 0.49 10.4 5.1 1.9 8.5 0.5 2.7 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like MgtE_N PF03448.12 EGO19140.1 - 1.7 8.9 5.5 0.64 10.3 1.1 2.2 3 0 0 3 3 3 0 MgtE intracellular N domain zf-C2H2_4 PF13894.1 EGO19141.1 - 2.9e-11 42.8 4.8 0.00011 22.3 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO19141.1 - 7.1e-11 41.7 7.5 2.5e-05 24.3 1.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO19141.1 - 6.4e-09 35.6 9.2 1.1e-07 31.7 2.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGO19141.1 - 0.0003 20.5 2.9 0.00061 19.5 0.5 2.5 2 2 0 2 2 2 1 C2H2-type zinc finger CHORD PF04968.7 EGO19141.1 - 0.025 14.7 3.2 0.5 10.6 0.4 2.1 1 1 1 2 2 2 0 CHORD zf-BED PF02892.10 EGO19141.1 - 0.054 13.2 3.1 3.6 7.4 0.3 2.4 1 1 1 2 2 2 0 BED zinc finger DUF1644 PF07800.7 EGO19141.1 - 0.1 12.4 1.5 0.16 11.8 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C2H2_jaz PF12171.3 EGO19141.1 - 0.13 12.4 2.4 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TauD PF02668.11 EGO19143.1 - 2.9e-49 168.0 0.6 4.9e-49 167.3 0.4 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TFIIIC_delta PF12657.2 EGO19144.1 - 5.1e-27 94.6 9.1 1.6e-26 93.0 2.8 2.9 3 1 1 4 4 4 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EGO19144.1 - 1.1e-23 82.9 1.0 2.6e-23 81.8 0.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.27 EGO19144.1 - 0.053 13.4 14.6 4.6 7.2 0.2 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat UPF0547 PF10571.4 EGO19144.1 - 0.25 11.0 2.9 12 5.7 0.7 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Glyco_hydro_47 PF01532.15 EGO19145.1 - 2.4e-143 478.0 0.0 2.8e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AdoMet_dc PF02675.10 EGO19146.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Trp_halogenase PF04820.9 EGO19147.1 - 2.2e-34 118.8 0.2 5.3e-17 61.5 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EGO19147.1 - 6.1e-15 55.1 0.0 1.1e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO19147.1 - 2e-09 36.8 0.1 5.4e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGO19147.1 - 6e-09 35.4 0.0 1.6e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO19147.1 - 2.5e-07 30.7 0.0 4.3e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO19147.1 - 7.4e-06 26.2 0.0 0.024 15.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO19147.1 - 1.3e-05 23.8 0.0 3.1e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO19147.1 - 4.3e-05 23.4 0.1 0.00015 21.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO19147.1 - 0.00026 19.9 0.1 0.00079 18.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EGO19147.1 - 0.00037 19.4 0.0 0.00064 18.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGO19147.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO19147.1 - 0.078 11.8 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 EGO19147.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acyl_transf_1 PF00698.16 EGO19148.1 - 4.2e-47 161.0 0.0 7.8e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGO19148.1 - 5.1e-47 160.4 0.0 9.9e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGO19148.1 - 7e-31 107.2 0.0 2e-28 99.2 0.0 2.4 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 EGO19148.1 - 2.5e-28 99.0 0.0 1.9e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGO19148.1 - 9.9e-27 93.1 0.0 2.1e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGO19148.1 - 2.7e-13 49.7 0.1 7.3e-07 28.6 0.0 3.2 3 1 0 4 4 4 2 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 EGO19148.1 - 3.7e-13 48.9 0.0 6.7e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGO19148.1 - 0.014 15.6 0.2 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site ACP_syn_III PF08545.5 EGO19148.1 - 0.014 15.0 1.8 0.027 14.1 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_23 PF13489.1 EGO19148.1 - 0.054 13.2 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain G0-G1_switch_2 PF15103.1 EGO19148.1 - 0.19 11.9 0.1 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 p450 PF00067.17 EGO19149.1 - 2e-65 221.1 0.0 2.8e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDC45 PF02724.9 EGO19150.1 - 0.071 11.1 13.5 0.094 10.7 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 EGO19150.1 - 0.13 11.7 13.0 0.2 11.0 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.8 EGO19150.1 - 0.2 11.2 18.1 0.36 10.4 12.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EGO19150.1 - 0.26 10.3 15.1 0.49 9.4 10.5 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO19150.1 - 1.4 6.7 17.2 0.75 7.6 10.0 1.7 2 0 0 2 2 2 0 Nop14-like family Mit_KHE1 PF10173.4 EGO19150.1 - 4.7 7.0 5.5 0.39 10.5 0.2 1.8 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Cwf_Cwc_15 PF04889.7 EGO19150.1 - 5 6.7 22.2 7.2 6.2 15.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ATG11 PF10377.4 EGO19152.1 - 0.031 14.1 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 11 COesterase PF00135.23 EGO19154.1 - 2.7e-79 267.2 0.0 3.6e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO19154.1 - 3.8e-08 33.1 0.0 7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO19154.1 - 0.0018 17.5 0.1 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO19154.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19154.1 - 0.042 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UBA_e1_C PF09358.5 EGO19155.1 - 0.046 13.8 0.1 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain SH3_9 PF14604.1 EGO19156.1 - 7.8e-07 28.5 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO19156.1 - 1.1e-05 24.6 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO19156.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Fe-S_biosyn PF01521.15 EGO19157.1 - 1.7e-12 47.2 0.0 2.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Peptidase_S10 PF00450.17 EGO19161.1 - 7.2e-109 364.6 0.1 9e-109 364.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGO19161.1 - 1e-05 25.5 0.0 7.7e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family GST_N_3 PF13417.1 EGO19163.1 - 8e-15 54.8 0.0 1.5e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19163.1 - 5.3e-11 42.3 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO19163.1 - 1.2e-05 25.3 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO19163.1 - 9.9e-05 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO19163.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO19163.1 - 0.0098 16.3 0.3 0.024 15.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO19165.1 - 6.1e-13 48.7 0.0 1e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19165.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO19165.1 - 0.006 16.7 0.0 0.0077 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribonuclease_3 PF00636.21 EGO19166.1 - 1.3e-41 141.5 0.0 8.5e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGO19166.1 - 3.3e-22 78.8 1.9 2.2e-09 37.3 0.0 4.8 2 2 1 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 EGO19166.1 - 2e-16 59.9 0.0 6.6e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 EGO19166.1 - 5.8e-14 51.6 0.0 1.8e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EGO19166.1 - 1.5e-12 47.2 0.0 3.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO19166.1 - 2.4e-09 37.2 0.0 6.2e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GST_N_3 PF13417.1 EGO19167.1 - 2.4e-15 56.5 0.0 5.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19167.1 - 1.4e-11 44.1 0.0 3.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO19167.1 - 0.0035 17.2 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO19167.1 - 0.0041 17.5 0.1 0.0077 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO19167.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_S10 PF00450.17 EGO19168.1 - 3.3e-26 92.4 0.0 3.5e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GFA PF04828.9 EGO19169.1 - 2.6e-10 40.1 0.0 2.6e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.20 EGO19176.1 - 5.3e-08 32.3 0.0 7.2e-06 25.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19176.1 - 0.00055 19.0 0.0 0.0067 15.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Alpha_kinase PF02816.13 EGO19177.1 - 9.6e-08 31.9 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family zf-TAZ PF02135.11 EGO19177.1 - 0.097 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 TAZ zinc finger DUF2576 PF10845.3 EGO19178.1 - 0.039 13.1 0.1 0.071 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) potato_inhibit PF00280.13 EGO19178.1 - 0.076 13.1 0.2 0.32 11.1 0.0 2.0 2 1 1 3 3 3 0 Potato inhibitor I family RVP_2 PF08284.6 EGO19180.1 - 0.098 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EGO19181.1 - 0.026 14.5 1.2 0.21 11.6 0.8 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.12 EGO19182.1 - 2.2e-06 27.6 0.7 6.3e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Peptidase_C32 PF05411.7 EGO19182.1 - 0.0057 16.3 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus putative proteinase COesterase PF00135.23 EGO19184.1 - 1.7e-99 333.9 0.1 3.3e-98 329.7 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO19184.1 - 1.5e-06 27.9 0.1 2.9e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO19184.1 - 0.00017 20.8 0.3 0.00032 19.9 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DAO PF01266.19 EGO19186.1 - 1e-48 166.0 0.0 1.5e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGO19186.1 - 5.7e-06 25.6 0.5 1.1e-05 24.6 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO19186.1 - 2.9e-05 23.1 6.8 0.00035 19.5 3.4 2.7 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO19186.1 - 0.0025 17.7 0.1 0.006 16.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO19186.1 - 0.0051 15.9 0.2 0.042 12.9 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO19186.1 - 0.0078 16.2 0.5 0.025 14.5 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EGO19186.1 - 0.019 14.5 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EGO19186.1 - 0.032 14.6 0.3 0.085 13.2 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO19186.1 - 0.045 12.6 0.2 1.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EGO19186.1 - 0.11 10.9 0.7 0.16 10.3 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EGO19186.1 - 0.11 11.5 0.8 0.44 9.6 0.1 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 EGO19186.1 - 0.17 10.7 0.1 0.73 8.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A AMP-binding PF00501.23 EGO19187.1 - 1.1e-74 251.3 0.0 1.4e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO19187.1 - 3e-08 34.4 0.0 2.6e-07 31.4 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain RRM_6 PF14259.1 EGO19188.1 - 2.2e-13 49.9 0.0 8.9e-11 41.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO19188.1 - 5.7e-10 38.6 2.3 0.00036 20.0 0.0 5.3 5 1 1 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO19188.1 - 1.2e-08 34.6 0.0 0.0049 16.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EGO19189.1 - 3.9e-24 85.4 0.0 5.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO19189.1 - 1.1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO19189.1 - 1.9e-07 30.9 0.0 3.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO19189.1 - 1.7e-05 24.4 0.1 6e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO19189.1 - 0.00046 19.1 0.0 0.0007 18.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO19189.1 - 0.00095 19.2 0.2 0.0029 17.6 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGO19189.1 - 0.0055 16.4 1.6 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EGO19189.1 - 0.035 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Na_H_Exchanger PF00999.16 EGO19191.1 - 4.7e-58 196.5 27.9 5.6e-58 196.2 19.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 EGO19191.1 - 0.71 9.1 7.3 0.14 11.4 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 NAD_binding_8 PF13450.1 EGO19192.1 - 1.7e-14 53.5 0.0 3.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGO19192.1 - 7.8e-12 45.0 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGO19192.1 - 0.00012 22.2 0.0 0.0003 20.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO19192.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO19192.1 - 0.015 15.1 0.0 0.065 13.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EGO19192.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.19 EGO19192.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EGO19193.1 - 8.6e-27 94.0 0.2 1.1e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO19193.1 - 2e-11 43.8 0.1 2.8e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGO19193.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EGO19193.1 - 0.0059 15.6 0.1 0.03 13.4 0.0 2.0 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EGO19193.1 - 0.15 11.8 0.2 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1422 PF07226.6 EGO19195.1 - 0.073 12.8 0.3 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1422) DUF3816 PF12822.2 EGO19195.1 - 0.091 12.6 2.4 0.1 12.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) p450 PF00067.17 EGO19197.1 - 6.1e-35 120.6 0.0 7.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_35 PF01301.14 EGO19198.1 - 2.4e-68 230.8 0.1 3.6e-68 230.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EGO19198.1 - 1.2e-40 138.2 15.5 1.6e-20 73.3 1.6 3.8 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EGO19198.1 - 7.8e-38 129.6 3.1 1.6e-37 128.6 2.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EGO19198.1 - 1.6e-19 69.0 2.2 3e-19 68.2 0.2 2.5 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.9 EGO19198.1 - 0.079 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase DUF2637 PF10935.3 EGO19199.1 - 0.033 14.1 1.3 0.27 11.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2637) XPG_N PF00752.12 EGO19200.1 - 4.4e-33 113.5 0.0 8.8e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGO19200.1 - 3.9e-27 94.1 0.0 8.2e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EGO19200.1 - 0.0006 20.0 0.0 0.0023 18.1 0.0 2.0 1 1 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Hap4_Hap_bind PF10297.4 EGO19201.1 - 6.5e-09 35.3 3.5 1.9e-08 33.8 2.4 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EGO19201.1 - 1.7e-06 27.8 20.0 0.00045 20.1 4.2 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EGO19201.1 - 0.024 14.4 20.0 0.57 10.0 6.0 2.9 1 1 1 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 EGO19201.1 - 0.036 14.4 3.7 0.088 13.1 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EGO19201.1 - 0.054 13.3 10.6 0.1 12.4 7.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 EGO19201.1 - 0.14 11.9 4.1 0.43 10.3 2.8 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper GAS PF13851.1 EGO19201.1 - 0.21 10.7 8.9 0.34 10.0 6.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 EGO19201.1 - 0.27 11.5 8.7 0.6 10.4 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Unstab_antitox PF09720.5 EGO19201.1 - 1.1 9.0 6.3 0.55 9.9 0.6 2.5 2 0 0 2 2 2 0 Putative addiction module component IncA PF04156.9 EGO19201.1 - 2 7.9 5.9 3.3 7.2 4.1 1.3 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 EGO19201.1 - 8.1 6.8 15.4 14 6.0 2.2 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.10 EGO19201.1 - 8.6 5.9 12.6 0.43 10.1 3.5 2.2 1 1 1 2 2 2 0 Septum formation initiator Pex24p PF06398.6 EGO19202.1 - 4.4e-25 88.2 0.2 5.7e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin AMP-binding PF00501.23 EGO19207.1 - 5.6e-22 77.7 0.0 3.7e-21 74.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 EGO19207.1 - 0.0057 15.2 0.1 0.02 13.4 0.1 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Trp_DMAT PF11991.3 EGO19208.1 - 3.4e-59 200.8 0.0 4e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Mso1_Sec1_bdg PF14475.1 EGO19208.1 - 0.032 13.6 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Sec1-binding region of Mso1 NAD_binding_10 PF13460.1 EGO19212.1 - 1.6e-14 54.3 0.0 2.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO19212.1 - 4.8e-06 26.1 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGO19212.1 - 3.4e-05 23.1 0.1 7.9e-05 22.0 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EGO19212.1 - 0.00061 19.2 0.1 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EGO19212.1 - 0.0014 18.4 0.2 0.003 17.3 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 EGO19212.1 - 0.012 14.5 0.0 0.058 12.2 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 EGO19212.1 - 0.012 15.5 0.1 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EGO19212.1 - 0.017 15.0 0.6 0.028 14.3 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 EGO19212.1 - 0.027 13.5 0.1 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.19 EGO19212.1 - 0.055 12.3 0.1 0.12 11.2 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO19212.1 - 0.068 13.5 0.1 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGO19212.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 EGO19212.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3HCDH_N PF02737.13 EGO19212.1 - 0.15 11.6 0.2 0.29 10.7 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 EGO19213.1 - 1.7e-79 266.9 0.0 2.6e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO19213.1 - 9.9e-49 166.3 0.0 3.7e-48 164.5 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGO19213.1 - 2.4e-36 124.1 0.2 4.9e-36 123.1 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EGO19213.1 - 6.5e-23 82.1 0.0 1.5e-21 77.6 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 EGO19213.1 - 3.4e-19 69.1 0.0 5.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EGO19213.1 - 3.2e-09 36.9 0.2 1.2e-08 35.0 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGO19213.1 - 1e-07 32.1 1.2 4.1e-06 26.8 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO19213.1 - 2.3e-05 24.1 0.1 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2974 PF11187.3 EGO19213.1 - 0.0025 17.1 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thiolase_N PF00108.18 EGO19213.1 - 0.003 16.5 0.1 0.0056 15.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.8 EGO19213.1 - 0.024 14.1 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold PhoH PF02562.11 EGO19215.1 - 0.068 12.3 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein UPF0114 PF03350.11 EGO19216.1 - 0.12 12.3 0.2 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Kinesin PF00225.18 EGO19218.1 - 3.7e-93 311.8 0.0 6.9e-93 310.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Pox_A_type_inc PF04508.7 EGO19218.1 - 0.037 13.8 5.6 0.16 11.7 2.4 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Rib_recp_KP_reg PF05104.7 EGO19219.1 - 1.3 9.5 9.1 2.5 8.5 6.3 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region YL1 PF05764.8 EGO19223.1 - 0.011 15.3 9.6 0.016 14.8 6.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein eIF3_subunit PF08597.5 EGO19223.1 - 0.15 11.5 10.1 0.27 10.7 7.0 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.9 EGO19223.1 - 0.33 8.9 6.8 0.46 8.4 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein COesterase PF00135.23 EGO19225.1 - 1.6e-76 258.1 0.2 3.4e-75 253.7 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO19225.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2235 PF09994.4 EGO19226.1 - 1e-77 261.2 0.2 1.3e-77 260.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EGO19226.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hist_deacetyl PF00850.14 EGO19227.1 - 5.4e-61 206.5 0.7 9.9e-61 205.7 0.3 1.6 2 0 0 2 2 2 1 Histone deacetylase domain PMI_typeI PF01238.16 EGO19228.1 - 1.9e-85 287.0 0.0 2.2e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EGO19228.1 - 6.3e-06 25.6 0.3 0.005 16.3 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EGO19228.1 - 0.0065 16.1 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain EutQ PF06249.7 EGO19228.1 - 0.019 14.5 0.1 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.2 EGO19228.1 - 0.15 11.7 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Cupin Ribosomal_S7 PF00177.16 EGO19229.1 - 4.9e-25 87.8 0.2 6.3e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3043 PF11241.3 EGO19229.1 - 0.049 13.2 0.4 0.075 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Mito_carr PF00153.22 EGO19230.1 - 1.1e-26 92.3 3.9 2.9e-14 52.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 EGO19231.1 - 3.3e-39 134.7 23.2 4.2e-39 134.3 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO19231.1 - 1.9e-34 118.9 29.1 1.9e-34 118.9 20.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGO19231.1 - 9.5e-08 30.8 19.0 1.6e-06 26.7 3.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 EGO19231.1 - 2.2e-05 23.1 23.4 0.0033 15.9 5.3 2.6 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EGO19231.1 - 0.0083 15.8 5.4 0.14 11.9 0.0 2.9 3 0 0 3 3 3 2 MFS_1 like family GNAT_acetyltr_2 PF13718.1 EGO19232.1 - 1.1e-75 253.3 0.0 1.9e-75 252.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGO19232.1 - 2e-67 226.2 0.0 7.5e-67 224.3 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EGO19232.1 - 2e-38 129.9 0.0 5.1e-38 128.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EGO19232.1 - 2.7e-34 117.2 0.4 7.7e-34 115.8 0.3 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EGO19232.1 - 0.00078 19.5 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.1 EGO19232.1 - 0.022 14.8 0.0 0.68 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.19 EGO19232.1 - 0.11 12.5 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Abhydrolase_6 PF12697.2 EGO19233.1 - 7.1e-12 45.6 0.1 1e-11 45.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO19233.1 - 1.6e-08 34.3 0.3 2.3e-08 33.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M24 PF00557.19 EGO19234.1 - 2.6e-44 151.2 0.1 3.2e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Abhydrolase_6 PF12697.2 EGO19235.1 - 1.3e-17 64.4 0.1 1.6e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO19235.1 - 4.8e-07 29.6 0.1 6.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19235.1 - 0.0012 18.4 0.2 0.0023 17.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ion_trans PF00520.26 EGO19236.1 - 7e-16 58.0 15.2 1.3e-15 57.2 10.5 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EGO19236.1 - 7.3e-11 41.6 5.2 7.3e-11 41.6 3.6 2.8 2 2 0 2 2 2 1 Ion channel Lig_chan PF00060.21 EGO19236.1 - 0.066 12.9 0.3 0.066 12.9 0.2 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel Arg_repressor PF01316.16 EGO19236.1 - 0.12 11.9 0.8 0.22 11.0 0.6 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain zf-CCHC_3 PF13917.1 EGO19237.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO19237.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO19237.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger COesterase PF00135.23 EGO19239.1 - 7.8e-83 278.9 0.1 8.5e-81 272.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Integrase_DNA PF02920.10 EGO19239.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase APH_6_hur PF04655.9 EGO19244.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase PF00069.20 EGO19245.1 - 1.6e-07 30.7 0.0 5.2e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19245.1 - 0.011 14.8 0.0 0.06 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase COesterase PF00135.23 EGO19246.1 - 5.6e-16 58.3 0.2 1.5e-13 50.3 0.2 2.9 2 1 0 2 2 2 2 Carboxylesterase family COQ9 PF08511.6 EGO19246.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 COQ9 zf-CCHC PF00098.18 EGO19248.1 - 3.8e-08 32.8 6.5 9.9e-08 31.5 2.6 2.5 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO19248.1 - 2.6e-07 30.6 2.3 3e-07 30.4 0.0 2.3 1 1 2 3 3 3 1 Retrotransposon gag protein Retrotrans_gag PF03732.12 EGO19249.1 - 6e-09 35.8 0.0 6e-09 35.8 0.0 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO19249.1 - 1.4e-08 34.2 4.0 2.5e-08 33.4 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO19249.1 - 0.017 14.8 2.7 0.043 13.5 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Herpes_UL55 PF04537.7 EGO19249.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein GTP_CH_N PF12471.3 EGO19250.1 - 4.2e-88 294.0 0.0 6e-88 293.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EGO19250.1 - 2.2e-15 56.2 0.0 3.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Abhydrolase_6 PF12697.2 EGO19252.1 - 2.7e-39 135.3 0.0 3.2e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19252.1 - 2.5e-25 89.3 0.0 2.2e-23 83.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO19252.1 - 1e-20 73.9 1.0 2e-20 73.0 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGO19252.1 - 2.1e-06 27.4 0.5 5.3e-06 26.1 0.3 1.6 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 EGO19252.1 - 7.8e-06 24.5 0.0 1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 EGO19252.1 - 1.7e-05 24.4 0.3 0.0027 17.3 0.1 2.3 1 1 1 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.5 EGO19252.1 - 3.4e-05 23.6 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 EGO19252.1 - 4.3e-05 23.2 0.0 9.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EGO19252.1 - 0.00015 21.1 0.1 0.38 9.9 0.0 2.2 1 1 1 2 2 2 2 Dienelactone hydrolase family DUF915 PF06028.6 EGO19252.1 - 0.0003 19.9 0.0 0.077 12.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.6 EGO19252.1 - 0.00069 19.3 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EGO19252.1 - 0.0022 17.4 0.5 2.1 7.7 0.1 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF676 PF05057.9 EGO19252.1 - 0.0024 17.1 0.2 0.0047 16.2 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Peptidase_S9 PF00326.16 EGO19252.1 - 0.0043 16.2 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 EGO19252.1 - 0.0057 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 EGO19252.1 - 0.0066 15.9 0.1 0.027 13.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.8 EGO19252.1 - 0.035 12.4 0.1 0.46 8.7 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.15 EGO19252.1 - 0.046 13.9 0.0 0.072 13.3 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 EGO19252.1 - 0.086 12.3 0.6 0.21 11.1 0.4 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold EHN PF06441.7 EGO19252.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Lipase_3 PF01764.20 EGO19252.1 - 0.15 11.6 0.2 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) DUF900 PF05990.7 EGO19252.1 - 0.16 11.2 0.1 0.64 9.2 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Amidohydro_1 PF01979.15 EGO19253.1 - 4.6e-09 36.3 0.6 1.2e-08 35.0 0.4 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGO19253.1 - 1.6e-08 34.2 0.0 4.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGO19253.1 - 9.2e-07 29.1 0.4 2.7e-06 27.6 0.3 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO19253.1 - 1.3e-06 27.9 0.2 9e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family VWA_2 PF13519.1 EGO19254.1 - 4.3e-07 30.2 0.0 7.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3421 PF11901.3 EGO19254.1 - 2.4e-06 27.2 0.0 0.016 14.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) VWA PF00092.23 EGO19254.1 - 5.6e-05 22.9 0.0 0.00065 19.4 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGO19254.1 - 0.044 13.5 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus CHASE2 PF05226.6 EGO19254.1 - 0.058 12.6 1.7 1.5 7.9 1.0 2.5 2 1 0 3 3 3 0 CHASE2 domain Ndc1_Nup PF09531.5 EGO19257.1 - 0.27 9.5 2.2 0.44 8.9 1.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cut8_N PF14482.1 EGO19258.1 - 0.064 13.2 0.5 0.064 13.2 0.4 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Sod_Fe_C PF02777.13 EGO19259.1 - 2.8e-35 120.3 0.1 5e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGO19259.1 - 2.7e-31 107.6 4.2 3.6e-31 107.2 1.6 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Carn_acyltransf PF00755.15 EGO19260.1 - 7e-157 523.0 0.0 9.4e-157 522.6 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DRMBL PF07522.9 EGO19262.1 - 9.3e-09 35.3 0.0 3.9e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGO19262.1 - 4.2e-08 32.9 0.1 9.9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO19262.1 - 0.0035 17.0 1.4 0.087 12.4 1.0 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EGO19262.1 - 0.041 13.6 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Mnd1 PF03962.10 EGO19262.1 - 4.9 6.7 7.9 0.41 10.2 1.7 1.9 2 0 0 2 2 2 0 Mnd1 family NAD_binding_6 PF08030.7 EGO19263.1 - 2.7e-05 24.1 0.0 8.1e-05 22.5 0.0 1.7 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Pyridox_oxidase PF01243.15 EGO19263.1 - 0.00016 21.5 0.0 0.0095 15.9 0.0 3.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 EGO19263.1 - 0.00022 21.7 0.0 0.17 12.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO19263.1 - 0.0043 17.1 0.0 0.61 10.2 0.0 2.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Aminotran_1_2 PF00155.16 EGO19264.1 - 6.1e-37 127.4 0.0 7.2e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGO19264.1 - 2.5e-05 22.7 0.0 3.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO19264.1 - 0.0001 21.4 0.4 0.00016 20.8 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EGO19264.1 - 0.035 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase ICMT PF04140.9 EGO19265.1 - 2.1e-13 50.2 0.0 3.9e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO19265.1 - 1.8e-11 44.0 0.1 3.2e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EGO19265.1 - 9.7e-05 21.0 0.2 0.00014 20.6 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EGO19266.1 - 4.7e-12 45.9 0.1 2.2e-11 43.7 0.0 2.1 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO19266.1 - 1.3e-09 38.0 0.7 4.8e-09 36.2 0.2 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EGO19266.1 - 5.8e-07 28.4 0.1 8.1e-07 27.9 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGO19266.1 - 0.054 12.7 0.1 0.091 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ATG22 PF11700.3 EGO19266.1 - 0.065 11.7 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGO19267.1 - 4e-18 65.2 39.4 1.6e-11 43.5 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO19267.1 - 2.3e-16 59.4 21.2 8.1e-16 57.6 14.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 EGO19268.1 - 0.0008 19.3 0.2 0.00091 19.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Kri1 PF05178.7 EGO19268.1 - 0.11 12.8 0.3 0.32 11.2 0.2 1.7 1 1 0 1 1 1 0 KRI1-like family PRP1_N PF06424.7 EGO19270.1 - 9.1e-48 161.9 10.1 9.2e-48 161.9 1.4 2.5 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGO19270.1 - 2e-26 90.0 25.3 0.035 14.7 0.0 14.0 5 5 10 15 15 15 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGO19270.1 - 5.4e-20 71.5 18.5 2.8e-06 27.8 0.0 8.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO19270.1 - 1.2e-13 51.1 13.9 0.0091 16.3 0.1 9.7 6 4 3 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO19270.1 - 2.2e-07 30.2 1.7 0.29 11.1 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO19270.1 - 3.1e-07 29.9 2.2 0.0072 15.9 0.0 6.8 7 3 3 10 10 10 2 TPR repeat TPR_6 PF13174.1 EGO19270.1 - 0.00035 20.8 10.4 5.7 7.6 0.0 7.8 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO19270.1 - 0.00042 20.1 0.8 5.4 7.0 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO19270.1 - 0.0061 16.2 0.0 0.88 9.4 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO19270.1 - 0.0096 15.4 0.1 5.6 6.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Ferritin PF00210.19 EGO19270.1 - 0.028 14.1 1.8 7 6.4 0.5 2.6 2 0 0 2 2 2 0 Ferritin-like domain TPR_9 PF13371.1 EGO19270.1 - 0.22 11.3 9.8 14 5.6 0.0 5.7 4 1 3 7 7 7 0 Tetratricopeptide repeat APH PF01636.18 EGO19271.1 - 2.2e-17 63.5 0.0 4.1e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGO19271.1 - 3.2e-06 26.0 0.1 2.6e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EGO19271.1 - 2.1e-05 24.2 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGO19271.1 - 0.0028 16.8 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase HipA_N PF07805.7 EGO19271.1 - 0.0031 17.7 0.1 0.0097 16.1 0.0 1.9 1 1 0 1 1 1 1 HipA-like N-terminal domain Kdo PF06293.9 EGO19271.1 - 0.0036 16.3 0.3 0.98 8.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO19271.1 - 0.01 15.2 0.7 0.032 13.5 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EGO19271.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain PASTA PF03793.14 EGO19271.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 PASTA domain SNN_transmemb PF09049.5 EGO19272.1 - 0.03 14.0 0.2 0.073 12.7 0.1 1.6 1 0 0 1 1 1 0 Stannin transmembrane PMP1_2 PF08114.6 EGO19272.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Pyr_redox_3 PF13738.1 EGO19273.1 - 1.7e-17 64.1 0.0 3.2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO19273.1 - 5.5e-11 42.3 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO19273.1 - 1.4e-05 24.8 2.3 2.2e-05 24.2 0.0 2.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding FMO-like PF00743.14 EGO19273.1 - 4.2e-05 21.9 0.2 0.00093 17.5 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGO19273.1 - 0.0069 16.2 0.0 0.043 13.6 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO19273.1 - 0.015 14.2 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO19273.1 - 0.1 11.4 0.1 0.55 9.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EGO19273.1 - 0.17 10.9 1.1 0.22 10.6 0.1 1.7 2 0 0 2 2 2 0 Thi4 family SNAPc19 PF15497.1 EGO19274.1 - 0.1 12.7 0.7 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DivIC PF04977.10 EGO19275.1 - 0.17 11.3 1.6 0.45 10.0 1.1 1.7 1 0 0 1 1 1 0 Septum formation initiator Pyr_redox_3 PF13738.1 EGO19276.1 - 4.4e-17 62.8 0.0 9.5e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO19276.1 - 1.8e-09 37.4 0.0 4.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EGO19276.1 - 1.5e-07 30.0 0.7 2.1e-05 22.9 0.1 3.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EGO19276.1 - 0.00013 21.7 0.0 0.0036 17.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EGO19276.1 - 0.0096 14.8 0.0 0.29 9.9 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO19276.1 - 0.02 14.7 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO19276.1 - 0.063 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family F-box-like PF12937.2 EGO19277.1 - 1.5e-07 31.0 0.4 8.9e-07 28.5 0.3 2.4 1 0 0 1 1 1 1 F-box-like G-patch_2 PF12656.2 EGO19279.1 - 2.3e-23 81.8 0.0 2.3e-23 81.8 0.0 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EGO19279.1 - 0.01 15.5 0.6 0.01 15.5 0.4 2.1 2 0 0 2 2 2 0 G-patch domain Amidohydro_4 PF13147.1 EGO19280.1 - 2e-08 34.6 0.8 3.1e-08 33.9 0.5 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EGO19280.1 - 4.5e-08 32.7 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGO19280.1 - 3.5e-06 26.9 0.3 5.8e-06 26.1 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase family Asp PF00026.18 EGO19281.1 - 8e-50 169.8 6.3 1.7e-49 168.7 4.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO19281.1 - 1.6e-05 24.9 0.3 0.00017 21.5 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO19281.1 - 0.00026 21.4 3.0 0.35 11.4 0.0 3.8 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EGO19281.1 - 0.00039 20.0 0.0 0.0018 17.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HECT PF00632.20 EGO19283.1 - 1.3e-94 316.9 0.0 1.5e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DAHP_synth_2 PF01474.11 EGO19284.1 - 1.2e-158 528.1 0.0 1.6e-158 527.6 0.0 1.2 1 0 0 1 1 1 1 Class-II DAHP synthetase family PEMT PF04191.8 EGO19285.1 - 8.1e-14 51.6 0.2 4.9e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EGO19285.1 - 5.4e-12 45.7 0.1 5.4e-12 45.7 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EGO19285.1 - 4e-07 28.9 0.2 5.9e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGO19285.1 - 0.00013 21.3 0.1 0.00022 20.6 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Flavi_NS2A PF01005.14 EGO19285.1 - 0.035 13.3 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A DUF4646 PF15496.1 EGO19286.1 - 1.1e-30 106.2 0.0 1.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) FAD-oxidase_C PF02913.14 EGO19288.1 - 3.6e-54 183.6 0.0 5.2e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO19288.1 - 1.2e-30 105.8 0.9 1.9e-30 105.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Cut8_N PF14482.1 EGO19291.1 - 0.064 13.2 0.5 0.064 13.2 0.4 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain M11L PF11099.3 EGO19293.1 - 0.077 12.7 0.5 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11L like GP41 PF00517.12 EGO19295.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein FliD_C PF07195.7 EGO19295.1 - 0.059 12.6 0.1 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF572 PF04502.8 EGO19295.1 - 0.071 12.3 0.5 0.084 12.0 0.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Fe-S_assembly PF04384.8 EGO19295.1 - 0.092 13.1 0.6 0.26 11.6 0.4 1.8 1 1 0 1 1 1 0 Iron-sulphur cluster assembly CCDC-167 PF15188.1 EGO19295.1 - 0.15 12.0 2.1 0.16 11.9 0.6 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 GMC_oxred_N PF00732.14 EGO19298.1 - 1.1e-53 182.3 0.0 2e-53 181.4 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO19298.1 - 7.1e-34 117.1 0.0 1.2e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EGO19298.1 - 3.9e-05 22.7 0.1 7.9e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EGO19298.1 - 5.1e-05 22.3 0.1 0.00011 21.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO19298.1 - 0.001 18.0 1.2 0.12 11.1 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EGO19298.1 - 0.0044 16.9 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO19298.1 - 0.0054 16.7 0.3 0.02 14.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO19298.1 - 0.029 14.1 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGO19298.1 - 0.034 14.5 0.3 1.6 9.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO19298.1 - 0.055 12.1 0.1 0.082 11.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.10 EGO19298.1 - 0.2 9.7 0.0 0.3 9.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Caleosin PF05042.8 EGO19299.1 - 1.7e-53 180.7 0.0 2.3e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 EGO19299.1 - 0.019 14.8 0.6 7.3 6.7 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.27 EGO19299.1 - 0.76 9.2 3.6 13 5.3 0.0 3.0 3 0 0 3 3 3 0 EF hand Helicase_C PF00271.26 EGO19300.1 - 1.1e-18 66.8 0.0 4.6e-15 55.2 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EGO19300.1 - 6.3e-09 35.5 0.0 1.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CN_hydrolase PF00795.17 EGO19301.1 - 5.4e-12 45.4 0.0 7.1e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Radical_SAM PF04055.16 EGO19302.1 - 7.4e-14 52.2 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily zf-CCHC PF00098.18 EGO19303.1 - 4.2e-07 29.5 4.4 1e-06 28.3 3.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO19303.1 - 1.2e-06 28.5 1.9 2.1e-06 27.7 0.1 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO19303.1 - 0.0067 16.1 4.1 0.038 13.7 0.6 2.4 2 0 0 2 2 2 1 Zinc knuckle NYD-SP28_assoc PF14775.1 EGO19303.1 - 0.012 15.2 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain gag-asp_proteas PF13975.1 EGO19304.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO19304.1 - 0.0021 18.5 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO19304.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease TFIIF_alpha PF05793.7 EGO19304.1 - 0.13 10.5 0.1 0.17 10.2 0.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4219 PF13961.1 EGO19306.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) MFS_1 PF07690.11 EGO19309.1 - 4.4e-23 81.5 55.3 9.5e-18 64.0 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EGO19311.1 - 1e-38 133.1 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.13 EGO19311.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Retrotrans_gag PF03732.12 EGO19311.1 - 0.11 12.6 0.6 0.41 10.7 0.2 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein SGS PF05002.10 EGO19314.1 - 3.3e-26 90.8 0.3 7.4e-26 89.7 0.2 1.6 1 0 0 1 1 1 1 SGS domain UvrD_C PF13361.1 EGO19314.1 - 2.1e-09 37.3 0.0 6.5e-07 29.1 0.0 2.5 1 1 0 2 2 2 2 UvrD-like helicase C-terminal domain CS PF04969.11 EGO19314.1 - 6.7e-08 32.9 0.1 1.6e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 CS domain UvrD-helicase PF00580.16 EGO19314.1 - 1.4e-06 27.8 0.1 0.00029 20.2 0.0 2.6 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EGO19314.1 - 6.8e-06 26.1 0.1 0.00022 21.3 0.0 3.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EGO19314.1 - 7e-05 22.9 0.0 0.0013 18.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EGO19314.1 - 0.0065 15.8 0.0 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Apc3 PF12895.2 EGO19314.1 - 4.1 7.6 6.8 0.63 10.2 0.2 3.0 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCHC PF00098.18 EGO19315.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO19315.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO19315.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle PepSY_TM_1 PF13172.1 EGO19316.1 - 5 7.0 7.3 0.85 9.4 1.8 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix Mito_carr PF00153.22 EGO19317.1 - 2.9e-57 190.3 5.0 3.7e-18 65.0 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA_int_end_N2 PF12928.2 EGO19318.1 - 3.1e-20 71.3 0.0 5.6e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EGO19318.1 - 0.0039 16.7 0.1 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain CRAL_TRIO_2 PF13716.1 EGO19319.1 - 2.3e-33 115.2 0.1 4e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EGO19319.1 - 5.3e-33 113.7 0.0 8.5e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EGO19319.1 - 0.00013 21.4 0.1 0.00037 20.0 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain Cation_efflux PF01545.16 EGO19320.1 - 2.5e-79 266.3 0.1 3.9e-79 265.6 0.0 1.3 1 1 0 1 1 1 1 Cation efflux family MerC PF03203.9 EGO19320.1 - 0.16 12.3 7.2 6.5 7.1 0.4 3.4 1 1 1 2 2 2 0 MerC mercury resistance protein DUF957 PF06117.6 EGO19322.1 - 0.21 11.1 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) DDE_Tnp_4 PF13359.1 EGO19323.1 - 5.7e-19 68.2 0.0 9.5e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EGO19325.1 - 2e-08 33.7 2.5 2e-08 33.7 1.7 2.1 2 0 0 2 2 2 1 Zinc knuckle CpXC PF14353.1 EGO19325.1 - 0.11 12.4 0.1 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 CpXC protein Retrotrans_gag PF03732.12 EGO19326.1 - 1.1e-07 31.8 0.6 2.1e-07 30.9 0.4 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein Mad3_BUB1_I PF08311.7 EGO19326.1 - 0.059 13.1 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 rve_2 PF13333.1 EGO19326.1 - 0.12 12.4 0.0 19 5.4 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Glyco_trans_1_3 PF13528.1 EGO19326.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 TPR_12 PF13424.1 EGO19327.1 - 0.018 14.9 0.5 1.3e+02 2.5 0.1 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO19327.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 TPR repeat Sec8_exocyst PF04048.9 EGO19327.1 - 0.11 12.0 1.5 0.35 10.5 0.2 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain SPRY PF00622.23 EGO19328.1 - 7.6e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain GDA1_CD39 PF01150.12 EGO19329.1 - 3.7e-84 282.7 0.0 4.9e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family bZIP_1 PF00170.16 EGO19330.1 - 3.1e-07 30.2 11.0 3.1e-07 30.2 7.6 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO19330.1 - 2.1e-05 24.2 12.1 2.1e-05 24.2 8.4 1.6 1 1 0 1 1 1 1 Basic region leucine zipper Sororin PF09666.5 EGO19330.1 - 0.2 11.8 5.6 0.072 13.2 2.1 1.6 2 0 0 2 2 2 0 Sororin protein CDC45 PF02724.9 EGO19330.1 - 1.2 7.0 6.0 1.6 6.6 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mitoc_L55 PF09776.4 EGO19330.1 - 2.3 7.8 6.4 6.3 6.4 4.4 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L55 OapA_N PF08525.6 EGO19331.1 - 0.2 11.4 0.6 0.42 10.4 0.4 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Glyco_hydro_88 PF07470.8 EGO19332.1 - 6e-15 55.1 0.6 8.6e-15 54.6 0.4 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 DDE_Tnp_4 PF13359.1 EGO19335.1 - 1.5e-10 40.9 0.0 2.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_88 PF07470.8 EGO19336.1 - 4.8e-15 55.4 0.1 8.1e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 BTB PF00651.26 EGO19337.1 - 5e-06 26.4 0.0 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Acetyltransf_1 PF00583.19 EGO19338.1 - 7.4e-14 51.5 0.0 1.4e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO19338.1 - 1.8e-10 40.4 0.0 1.2e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO19338.1 - 3.9e-08 33.3 0.0 5.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO19338.1 - 1.5e-06 28.2 0.0 7.6e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO19338.1 - 2.7e-06 27.6 0.0 3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO19338.1 - 1e-05 25.4 0.0 3.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO19338.1 - 0.00025 20.8 0.0 0.00059 19.6 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGO19338.1 - 0.00074 19.3 0.0 0.0041 16.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO19338.1 - 0.036 14.0 0.0 0.32 10.9 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGO19338.1 - 0.083 12.6 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PDT PF00800.13 EGO19339.1 - 2e-49 167.5 0.0 2.5e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase MFS_1 PF07690.11 EGO19340.1 - 3.2e-28 98.4 36.7 4.7e-19 68.3 4.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO19340.1 - 2.1e-25 89.2 16.4 8.7e-24 83.9 0.4 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4106 PF13388.1 EGO19341.1 - 0.054 12.4 0.3 0.053 12.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Kin17_mid PF10357.4 EGO19342.1 - 4.3e-48 162.1 0.6 7e-48 161.4 0.4 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EGO19342.1 - 0.00037 20.5 3.8 0.00075 19.6 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO19342.1 - 0.0055 16.8 3.4 0.012 15.7 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO19342.1 - 0.0096 16.0 1.9 0.05 13.7 0.5 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 EGO19342.1 - 0.11 11.8 0.9 0.24 10.7 0.6 1.5 1 0 0 1 1 1 0 Life-span regulatory factor DUF2407_C PF13373.1 EGO19343.1 - 4.9e-22 78.3 7.7 9.9e-18 64.4 2.0 3.1 2 1 0 2 2 2 2 DUF2407 C-terminal domain DUF2407 PF10302.4 EGO19343.1 - 5.8e-17 61.6 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGO19343.1 - 2.4e-07 30.0 0.0 1.7e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family UPF0118 PF01594.11 EGO19343.1 - 0.052 12.5 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 IBN_N PF03810.14 EGO19344.1 - 8.9e-10 38.3 0.0 3.3e-07 30.1 0.0 3.1 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGO19344.1 - 0.00011 22.4 3.9 0.03 14.5 0.1 3.5 4 0 0 4 4 4 2 HEAT repeats Cse1 PF08506.5 EGO19344.1 - 0.0017 16.9 0.0 0.0061 15.1 0.0 1.8 2 0 0 2 2 2 1 Cse1 HEAT_EZ PF13513.1 EGO19344.1 - 0.0077 16.6 1.9 2.8 8.5 0.1 5.1 5 0 0 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 EGO19344.1 - 0.058 13.2 0.4 0.29 11.0 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2435) Actin PF00022.14 EGO19345.1 - 1.8e-75 253.8 0.0 2.1e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Actin Zn_clus PF00172.13 EGO19346.1 - 2.5e-08 33.6 7.2 2.5e-08 33.6 5.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTG PF07742.7 EGO19350.1 - 0.021 14.2 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 BTG family PSS PF03034.10 EGO19353.1 - 2e-100 335.8 8.7 2.6e-100 335.4 6.0 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3918 PF13056.1 EGO19353.1 - 0.035 13.4 0.1 0.084 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GH3 PF03321.8 EGO19354.1 - 1.2e-63 215.5 0.0 1.4e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter GSDH PF07995.6 EGO19354.1 - 0.029 13.4 0.0 4.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Pkinase PF00069.20 EGO19357.1 - 6.3e-10 38.6 0.0 1.5e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19357.1 - 0.014 14.4 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase FAST_2 PF08368.7 EGO19357.1 - 0.015 15.6 0.1 0.25 11.7 0.0 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Nop PF01798.13 EGO19360.1 - 4.5e-58 194.8 0.0 8.5e-58 193.9 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGO19360.1 - 4.1e-24 84.1 0.1 8e-24 83.2 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGO19360.1 - 4.9e-22 77.8 1.0 4.9e-22 77.8 0.7 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain LamB_YcsF PF03746.11 EGO19363.1 - 0.042 12.9 0.0 0.042 12.9 0.0 1.0 1 0 0 1 1 1 0 LamB/YcsF family RNA_pol_Rpb8 PF03870.10 EGO19374.1 - 4.1e-40 137.1 0.1 8e-40 136.2 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb8 Oxidored_molyb PF00174.14 EGO19375.1 - 3.1e-46 156.8 0.0 5.6e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGO19375.1 - 4.8e-23 81.2 1.5 7.5e-23 80.6 1.1 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain HCBP_related PF06594.6 EGO19375.1 - 0.12 11.9 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain PvlArgDC PF01862.11 EGO19377.1 - 0.12 12.0 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) F-box PF00646.28 EGO19380.1 - 2e-06 27.2 0.2 5.5e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGO19380.1 - 1.7e-05 24.4 0.2 8.3e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like YTH PF04146.10 EGO19381.1 - 2.1e-51 173.2 0.0 4.2e-51 172.2 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain Phage_CP76 PF06892.6 EGO19385.1 - 0.083 12.2 0.0 4.6 6.5 0.0 2.0 1 1 1 2 2 2 0 Phage regulatory protein CII (CP76) WD40 PF00400.27 EGO19386.1 - 1.2e-33 113.7 1.2 6.5e-10 38.5 0.1 6.8 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO19386.1 - 4.2e-06 25.1 0.3 2.1e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGO19386.1 - 0.00016 21.2 0.3 0.00026 20.5 0.2 1.5 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 EGO19386.1 - 0.0026 16.1 0.0 0.004 15.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EGO19386.1 - 0.01 14.6 0.1 0.044 12.5 0.0 1.7 1 1 0 2 2 2 0 Nup133 N terminal like HAD_2 PF13419.1 EGO19389.1 - 9.2e-14 52.0 0.1 4.9e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO19389.1 - 7.8e-13 49.3 0.5 3.3e-12 47.2 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO19389.1 - 1.8e-07 30.7 0.1 4.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGO19389.1 - 0.036 14.2 0.0 0.054 13.6 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_hydro_71 PF03659.9 EGO19393.1 - 7.8e-96 320.8 14.9 9.6e-96 320.5 10.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 FYRN PF05964.9 EGO19394.1 - 9.6e-17 60.1 0.1 1.9e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 EGO19394.1 - 1.4e-15 56.8 0.0 2.5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 F/Y rich C-terminus AA_permease PF00324.16 EGO19395.1 - 3.1e-105 352.2 41.5 3.7e-105 352.0 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO19395.1 - 3.4e-35 121.3 46.2 4.5e-35 121.0 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 EGO19395.1 - 0.012 14.5 2.4 0.7 8.8 0.0 3.1 1 1 1 2 2 2 0 Peptidase family M50 UPF0154 PF03672.8 EGO19395.1 - 2.3 7.8 4.9 3.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) AA_permease PF00324.16 EGO19396.1 - 2.2e-98 329.6 40.9 2.6e-98 329.4 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO19396.1 - 6.6e-32 110.5 43.0 9e-32 110.1 29.8 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 EGO19396.1 - 0.21 10.5 6.6 0.71 8.7 0.1 3.2 1 1 1 2 2 2 0 Peptidase family M50 TAF PF02969.12 EGO19397.1 - 5.2e-26 90.3 0.1 9.2e-26 89.5 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EGO19397.1 - 1.4e-15 57.2 0.0 3.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 EGO19397.1 - 3.7e-05 23.7 0.2 0.00011 22.2 0.1 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HEAT_EZ PF13513.1 EGO19397.1 - 0.0054 17.1 2.7 4.1 8.0 0.0 4.4 3 2 2 5 5 5 1 HEAT-like repeat Bromo_TP PF07524.8 EGO19397.1 - 0.0064 16.2 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated DUF3385 PF11865.3 EGO19397.1 - 0.021 14.7 1.1 0.067 13.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) TFIID-31kDa PF02291.10 EGO19397.1 - 0.029 14.1 0.4 0.09 12.5 0.0 2.0 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit Glyco_hydro_61 PF03443.9 EGO19398.1 - 8.4e-48 163.0 0.3 1e-47 162.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-CCHC PF00098.18 EGO19400.1 - 0.015 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EGO19403.1 - 1.5e-16 60.0 30.4 1.5e-16 60.0 21.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO19403.1 - 7e-14 51.6 5.5 7e-14 51.6 3.8 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Pkinase PF00069.20 EGO19404.1 - 8.9e-47 159.4 0.0 3e-46 157.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19404.1 - 2.7e-23 82.3 0.0 2.8e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO19404.1 - 7.5e-05 21.8 0.1 0.00057 18.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO19404.1 - 0.0026 17.5 0.2 0.044 13.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO19404.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO19404.1 - 0.036 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Ald_Xan_dh_C2 PF02738.13 EGO19404.1 - 0.044 12.0 0.0 0.062 11.6 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Spindle_Spc25 PF08234.7 EGO19405.1 - 2.6e-22 78.5 0.7 6.5e-22 77.3 0.1 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF342 PF03961.8 EGO19405.1 - 0.00033 19.2 4.7 0.00042 18.8 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF4200 PF13863.1 EGO19405.1 - 0.00072 19.5 11.7 0.00072 19.5 8.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) ERM PF00769.14 EGO19405.1 - 0.00081 18.9 8.6 0.001 18.6 6.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family IncA PF04156.9 EGO19405.1 - 0.0011 18.6 6.1 0.0013 18.3 4.3 1.1 1 0 0 1 1 1 1 IncA protein Filament PF00038.16 EGO19405.1 - 0.0013 18.2 3.8 0.0017 17.8 2.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein Rootletin PF15035.1 EGO19405.1 - 0.0045 16.9 6.7 0.0063 16.5 4.7 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 EGO19405.1 - 0.0065 16.3 9.6 0.035 13.9 6.6 1.9 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4019 PF13211.1 EGO19405.1 - 0.0074 16.5 0.4 0.016 15.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4019) DHquinase_I PF01487.10 EGO19405.1 - 0.0084 15.7 0.9 4.8 6.7 0.6 2.4 2 1 1 3 3 2 2 Type I 3-dehydroquinase AAA_13 PF13166.1 EGO19405.1 - 0.021 13.3 5.6 0.027 12.9 3.9 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EGO19405.1 - 0.021 13.8 6.9 0.033 13.2 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 EGO19405.1 - 0.035 13.9 4.3 0.053 13.3 3.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CorA PF01544.13 EGO19405.1 - 0.047 12.7 1.2 0.086 11.8 0.6 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Potyvirid-P3 PF13608.1 EGO19405.1 - 0.05 12.7 4.7 0.068 12.2 3.3 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Fmp27_WPPW PF10359.4 EGO19405.1 - 0.073 11.4 4.0 0.092 11.1 2.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 EGO19405.1 - 0.088 12.3 6.0 0.16 11.5 3.8 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LURAP PF14854.1 EGO19405.1 - 0.17 11.5 2.0 5 6.8 0.2 2.3 1 1 1 2 2 2 0 Leucine rich adaptor protein Syntaxin-6_N PF09177.6 EGO19405.1 - 0.35 11.3 3.8 0.93 9.9 2.4 1.9 1 1 1 2 2 1 0 Syntaxin 6, N-terminal Ax_dynein_light PF10211.4 EGO19405.1 - 0.58 9.9 10.9 0.21 11.4 5.4 1.7 1 1 1 2 2 2 0 Axonemal dynein light chain Mnd1 PF03962.10 EGO19405.1 - 0.95 9.0 10.7 1.4 8.5 7.1 1.5 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 EGO19405.1 - 0.95 9.8 6.1 2.8 8.3 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Smg4_UPF3 PF03467.10 EGO19405.1 - 1.1 9.2 5.0 0.84 9.6 2.3 1.6 1 1 0 1 1 1 0 Smg-4/UPF3 family GrpE PF01025.14 EGO19405.1 - 1.7 8.1 8.0 5.3 6.5 5.4 1.8 1 1 0 1 1 1 0 GrpE HAUS6_N PF14661.1 EGO19405.1 - 2.3 7.4 10.4 3.7 6.8 2.9 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.17 EGO19405.1 - 3 7.9 8.4 9.6 6.2 5.5 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.9 EGO19405.1 - 3.2 7.3 11.3 8.2 6.0 7.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF2228 PF10228.4 EGO19405.1 - 3.6 7.0 5.9 13 5.1 2.2 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) zf-ribbon_3 PF13248.1 EGO19406.1 - 0.029 13.5 0.2 0.065 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF2863 PF11062.3 EGO19406.1 - 0.045 11.8 0.1 0.061 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) DMPK_coil PF08826.5 EGO19408.1 - 0.027 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like Tropomyosin PF00261.15 EGO19408.1 - 0.084 11.9 0.4 0.11 11.5 0.3 1.1 1 0 0 1 1 1 0 Tropomyosin rve PF00665.21 EGO19409.1 - 0.00026 21.0 0.0 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO19409.1 - 0.0046 16.8 0.1 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 CDC45 PF02724.9 EGO19413.1 - 0.2 9.6 14.0 0.28 9.1 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 EGO19413.1 - 0.21 11.0 13.9 0.34 10.3 9.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.8 EGO19413.1 - 0.22 11.1 17.5 0.38 10.3 12.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EGO19413.1 - 1.1 8.2 16.5 1.8 7.5 11.5 1.3 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 EGO19413.1 - 2.9 7.5 20.9 4.1 7.0 14.5 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF3_subunit PF08597.5 EGO19413.1 - 6.1 6.3 18.2 0.47 9.9 9.1 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Nop14 PF04147.7 EGO19413.1 - 9.7 3.9 19.3 4.7 5.0 11.2 1.7 2 0 0 2 2 2 0 Nop14-like family ARHGEF5_35 PF15441.1 EGO19414.1 - 0.027 13.2 0.2 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 TB2_DP1_HVA22 PF03134.14 EGO19415.1 - 1.5e-27 95.1 4.5 2.6e-27 94.4 3.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3792 PF12670.2 EGO19416.1 - 0.0035 17.1 1.2 0.0044 16.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) ABC2_membrane_3 PF12698.2 EGO19416.1 - 0.0062 15.6 4.5 0.0066 15.5 3.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein UPF0197 PF05251.7 EGO19416.1 - 0.028 14.7 3.6 0.039 14.2 2.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Fig1 PF12351.3 EGO19416.1 - 0.12 12.2 2.1 0.12 12.1 1.4 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 QCR10 PF09796.4 EGO19416.1 - 2.6 7.7 5.8 10 5.8 0.5 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TFIIS_C PF01096.13 EGO19417.1 - 9.5e-18 63.5 7.9 1.1e-17 63.3 0.5 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGO19417.1 - 4.7e-07 29.3 0.5 4.7e-07 29.3 0.3 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.3 EGO19417.1 - 1.9e-05 23.9 2.9 6.6e-05 22.2 0.4 2.5 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 EGO19417.1 - 5e-05 23.0 7.1 0.0011 18.7 0.2 2.7 2 1 0 2 2 2 1 Double zinc ribbon DUF2387 PF09526.5 EGO19417.1 - 5.3e-05 23.0 4.7 0.02 14.8 0.3 2.3 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.1 EGO19417.1 - 5.5e-05 22.2 7.0 0.16 11.2 0.0 3.8 4 0 0 4 4 4 2 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EGO19417.1 - 0.00027 20.6 8.7 0.54 10.0 0.8 3.4 3 1 0 3 3 3 2 PhnA Zinc-Ribbon IBR PF01485.16 EGO19417.1 - 0.0025 17.6 7.3 0.029 14.2 0.1 2.5 2 1 0 2 2 2 1 IBR domain Zn_Tnp_IS1595 PF12760.2 EGO19417.1 - 0.0037 17.0 10.8 0.0099 15.6 0.8 3.2 2 1 1 3 3 3 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGO19417.1 - 0.0055 16.3 7.3 0.26 10.9 0.2 2.5 2 1 0 2 2 2 2 Putative transposase DNA-binding domain DNA_ligase_ZBD PF03119.11 EGO19417.1 - 0.009 15.6 0.7 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2296 PF10058.4 EGO19417.1 - 0.01 15.5 3.5 18 5.1 0.0 3.9 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) Lar_restr_allev PF14354.1 EGO19417.1 - 0.014 15.6 8.3 0.093 13.0 0.3 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar UPF0547 PF10571.4 EGO19417.1 - 0.018 14.7 0.3 0.018 14.7 0.2 3.1 3 1 2 5 5 4 0 Uncharacterised protein family UPF0547 PHF5 PF03660.9 EGO19417.1 - 0.05 13.6 1.9 4.8 7.2 0.1 2.3 2 0 0 2 2 2 0 PHF5-like protein zf-tcix PF14952.1 EGO19417.1 - 0.11 11.8 1.2 11 5.4 0.0 2.6 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Cytochrome_C554 PF13435.1 EGO19417.1 - 0.13 12.2 5.8 0.19 11.7 4.1 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Cys_rich_CPCC PF14206.1 EGO19417.1 - 0.2 11.2 5.5 0.37 10.3 0.1 2.5 3 0 0 3 3 2 0 Cysteine-rich CPCC PHD PF00628.24 EGO19417.1 - 0.21 11.2 10.1 2 8.1 0.7 2.7 2 1 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.7 EGO19417.1 - 0.34 10.7 7.6 0.43 10.4 0.5 2.4 2 1 0 2 2 2 0 zinc-ribbons Stc1 PF12898.2 EGO19417.1 - 0.36 10.9 4.7 0.95 9.5 3.3 1.7 1 1 0 1 1 1 0 Stc1 domain DNA_RNApol_7kD PF03604.8 EGO19417.1 - 0.53 9.8 7.8 1.4 8.4 0.5 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF164 PF02591.10 EGO19417.1 - 0.57 10.0 5.3 9.5 6.1 0.0 3.6 4 0 0 4 4 4 0 Putative zinc ribbon domain zinc_ribbon_5 PF13719.1 EGO19417.1 - 0.59 9.7 11.7 6.7 6.3 0.2 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 EGO19417.1 - 0.72 9.8 9.2 22 5.1 1.9 3.7 3 1 1 4 4 4 0 zinc-finger HypA PF01155.14 EGO19417.1 - 0.93 9.1 7.6 0.96 9.1 0.3 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EGO19417.1 - 0.95 9.0 12.7 1.2 8.6 1.3 3.4 3 1 0 3 3 2 0 zinc-ribbon domain zf-UBR PF02207.15 EGO19417.1 - 1.3 8.7 7.4 0.55 10.0 0.3 2.6 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) A2L_zn_ribbon PF08792.5 EGO19417.1 - 1.3 8.5 0.0 1.3 8.5 0.0 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-CHY PF05495.7 EGO19417.1 - 1.6 8.9 10.3 1.5 9.0 1.0 3.2 2 2 0 2 2 2 0 CHY zinc finger Zn_ribbon_recom PF13408.1 EGO19417.1 - 1.6 9.0 6.4 5.3 7.3 0.2 2.6 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.14 EGO19417.1 - 1.6 8.2 7.3 7 6.2 0.2 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.5 EGO19417.1 - 2.1 8.3 15.4 9.7 6.2 0.3 3.9 2 2 1 4 4 4 0 Zinc ribbon domain Cytochrom_CIII PF02085.11 EGO19417.1 - 2.3 8.3 8.5 4.1 7.5 5.3 1.8 1 1 0 1 1 1 0 Class III cytochrome C family zf-FPG_IleRS PF06827.9 EGO19417.1 - 2.4 7.9 8.2 6.3 6.5 0.5 2.9 3 1 0 3 3 2 0 Zinc finger found in FPG and IleRS zf-NADH-PPase PF09297.6 EGO19417.1 - 2.4 7.7 11.1 13 5.4 0.3 3.3 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rpr2 PF04032.11 EGO19417.1 - 2.5 8.0 8.6 1.1e+02 2.7 6.0 2.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C4pol PF14260.1 EGO19417.1 - 3.4 7.7 6.5 1.8 8.6 1.6 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zinc_ribbon_4 PF13717.1 EGO19417.1 - 3.5 7.3 12.4 5.2 6.8 0.2 3.9 3 1 0 3 3 3 0 zinc-ribbon domain GFA PF04828.9 EGO19417.1 - 3.8 7.5 7.7 2 8.4 0.5 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.19 EGO19417.1 - 3.9 7.4 10.6 4 7.4 0.2 3.7 4 0 0 4 4 4 0 B-box zinc finger Ribosomal_S27e PF01667.12 EGO19417.1 - 4.4 6.9 7.9 3 7.4 0.8 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 Auto_anti-p27 PF06677.7 EGO19417.1 - 7.3 6.4 11.4 3 7.6 1.3 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Peptidase_M1 PF01433.15 EGO19420.1 - 1.7e-58 198.6 0.0 2.3e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EGO19420.1 - 2e-29 102.0 0.0 4e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EGO19420.1 - 4.3e-12 46.1 0.1 7.9e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF4506 PF14958.1 EGO19420.1 - 0.11 12.0 0.0 4.8 6.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4506) YL1 PF05764.8 EGO19422.1 - 4.8e-26 91.8 11.5 6.7e-26 91.3 8.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EGO19422.1 - 5.5e-11 41.8 0.1 9.7e-11 41.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MutS_V PF00488.16 EGO19423.1 - 5.7e-65 219.0 0.0 9.4e-36 123.3 0.0 2.3 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 EGO19423.1 - 4.2e-33 114.8 4.3 9.6e-33 113.6 3.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGO19423.1 - 4e-09 36.5 0.2 8.8e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EGO19423.1 - 0.0012 18.8 0.2 0.006 16.6 0.0 2.3 2 1 0 2 2 2 1 MutS domain II DAO PF01266.19 EGO19425.1 - 3.3e-31 108.4 0.1 6.9e-31 107.4 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO19425.1 - 0.024 14.6 4.4 0.025 14.6 0.0 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO19425.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Vps35 PF03635.12 EGO19427.1 - 0 1053.1 5.2 0 1052.9 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 BCIP PF13862.1 EGO19429.1 - 2.1e-61 206.8 0.0 2.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Pro_dh PF01619.13 EGO19430.1 - 2.7e-41 141.5 0.0 1.1e-39 136.3 0.0 2.4 1 1 0 1 1 1 1 Proline dehydrogenase TIP120 PF08623.5 EGO19431.1 - 1.8e-53 180.6 2.5 4.2e-53 179.3 0.1 2.8 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EGO19431.1 - 6.1e-15 55.2 15.9 0.067 13.4 0.3 8.3 6 1 2 8 8 7 6 HEAT repeats HEAT PF02985.17 EGO19431.1 - 6.9e-14 50.6 24.7 0.0029 17.5 0.0 12.6 14 0 0 14 14 13 4 HEAT repeat HEAT_EZ PF13513.1 EGO19431.1 - 1.4e-12 47.7 30.4 0.0089 16.5 0.1 11.9 11 3 2 13 13 11 4 HEAT-like repeat Cnd1 PF12717.2 EGO19431.1 - 6.9e-10 39.0 4.2 0.086 12.6 0.1 6.2 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGO19431.1 - 6.5e-08 32.8 0.7 1.5 9.2 0.0 7.3 7 2 1 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EGO19431.1 - 3e-07 30.0 12.3 0.0061 15.9 0.1 5.9 7 0 0 7 7 7 2 CLASP N terminal Adaptin_N PF01602.15 EGO19431.1 - 4.7e-07 28.5 9.1 0.0081 14.5 0.0 6.4 5 1 1 6 6 6 2 Adaptin N terminal region MMS19_C PF12460.3 EGO19431.1 - 3.1e-06 26.1 18.1 0.01 14.5 0.3 5.3 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal ParcG PF10274.4 EGO19431.1 - 0.00076 19.4 3.6 0.63 9.9 0.0 5.2 6 0 0 6 6 6 1 Parkin co-regulated protein UME PF08064.8 EGO19431.1 - 0.00089 19.1 2.9 1.9 8.4 0.0 4.6 5 0 0 5 5 4 1 UME (NUC010) domain RIX1 PF08167.7 EGO19431.1 - 0.0011 18.6 16.2 1.9 8.1 0.0 7.4 5 2 3 8 8 8 1 rRNA processing/ribosome biogenesis DUF2454 PF10521.4 EGO19431.1 - 0.0025 16.8 3.5 1.3 7.9 0.1 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) DUF3385 PF11865.3 EGO19431.1 - 0.021 14.7 5.4 0.064 13.1 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) DUF2435 PF10363.4 EGO19431.1 - 0.046 13.6 3.9 0.29 11.0 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Sec7_N PF12783.2 EGO19431.1 - 1.1 8.6 5.4 1.2 8.5 0.5 3.3 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AAA PF00004.24 EGO19433.1 - 9.1e-42 142.3 0.0 1.9e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGO19433.1 - 7.2e-27 93.0 0.1 5.3e-26 90.2 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EGO19433.1 - 4.4e-20 71.3 4.8 4.4e-20 71.3 3.3 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.9 EGO19433.1 - 6e-06 26.0 0.0 2.2e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO19433.1 - 9.2e-06 25.8 1.0 0.00098 19.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGO19433.1 - 1.2e-05 24.4 0.0 3.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGO19433.1 - 2.4e-05 23.8 0.0 6.4e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGO19433.1 - 2.5e-05 25.0 0.0 0.0001 23.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO19433.1 - 3.4e-05 23.7 0.1 0.0001 22.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGO19433.1 - 4.1e-05 23.6 0.0 0.0016 18.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGO19433.1 - 0.0001 22.5 0.3 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF4407 PF14362.1 EGO19433.1 - 0.00027 19.9 1.3 0.00042 19.3 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) AAA_33 PF13671.1 EGO19433.1 - 0.00032 20.6 0.1 0.0016 18.3 0.0 2.1 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EGO19433.1 - 0.00054 18.7 0.3 0.0013 17.5 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EGO19433.1 - 0.00075 18.9 0.3 0.22 10.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO19433.1 - 0.0014 18.5 0.0 0.0065 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGO19433.1 - 0.0019 17.1 0.0 0.0042 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EGO19433.1 - 0.0056 16.2 0.1 0.015 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EGO19433.1 - 0.0092 16.1 0.0 0.0092 16.1 0.0 1.9 2 0 0 2 2 1 1 RNA helicase ResIII PF04851.10 EGO19433.1 - 0.012 15.4 0.2 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EGO19433.1 - 0.012 14.7 0.0 3 6.8 0.0 2.3 1 1 1 2 2 2 0 KaiC Arch_ATPase PF01637.13 EGO19433.1 - 0.03 14.0 2.6 0.3 10.7 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 EGO19433.1 - 0.031 13.4 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGO19433.1 - 0.033 13.4 0.1 0.083 12.1 0.1 1.8 1 1 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EGO19433.1 - 0.035 13.7 0.0 0.25 10.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EGO19433.1 - 0.041 12.9 0.1 0.3 10.1 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.12 EGO19433.1 - 0.054 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EGO19433.1 - 0.057 13.1 0.0 0.057 13.1 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain Guanylate_kin PF00625.16 EGO19433.1 - 0.087 12.2 1.0 0.33 10.3 0.0 2.3 3 0 0 3 3 3 0 Guanylate kinase TPR_3 PF07720.7 EGO19433.1 - 0.095 12.5 1.3 0.23 11.2 0.9 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma54_activ_2 PF14532.1 EGO19433.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Spore_GerAC PF05504.6 EGO19433.1 - 0.13 12.0 1.2 0.23 11.2 0.8 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Sigma54_activat PF00158.21 EGO19433.1 - 0.15 11.5 0.0 0.57 9.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF3987 PF13148.1 EGO19433.1 - 0.37 9.2 3.3 0.55 8.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TPR_2 PF07719.12 EGO19433.1 - 0.59 10.1 3.2 7.4 6.7 0.3 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EGO19434.1 - 1.2e-65 221.2 0.0 1.4e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19434.1 - 1.2e-24 86.8 0.0 2.1e-24 86.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO19434.1 - 4.7e-06 25.7 0.2 1.5e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Ribosomal_L19e PF01280.15 EGO19435.1 - 8.7e-61 204.0 12.1 8.7e-61 204.0 8.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 EGO19435.1 - 0.0014 18.0 0.1 0.0045 16.3 0.0 1.9 1 0 0 1 1 1 1 S4 domain DUF2102 PF09875.4 EGO19435.1 - 1.4 8.5 4.3 2.3 7.7 0.4 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) MOZ_SAS PF01853.13 EGO19436.1 - 4.3e-63 211.9 0.3 6e-63 211.5 0.2 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 EGO19436.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Tudor-knot PF11717.3 EGO19437.1 - 4.4e-10 39.1 0.5 6.5e-10 38.5 0.4 1.3 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EGO19437.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain COesterase PF00135.23 EGO19438.1 - 6.1e-79 266.1 0.0 6.8e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO19438.1 - 9e-06 25.4 0.1 9.5e-05 22.0 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO19438.1 - 0.034 13.8 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 EGO19440.1 - 0.018 14.7 0.5 0.033 13.8 0.3 1.5 1 0 0 1 1 1 0 F-box-like Herpes_glycop PF01528.11 EGO19442.1 - 0.053 12.2 0.1 0.065 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF1183 PF06682.7 EGO19442.1 - 0.06 12.9 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) HSDR_N PF04313.9 EGO19443.1 - 0.066 12.9 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Phosphoesterase PF04185.9 EGO19445.1 - 6.8e-24 84.7 6.1 1.5e-23 83.6 4.2 1.5 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 EGO19446.1 - 1.1e-44 150.9 2.5 1.1e-44 150.9 1.8 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO19446.1 - 3.8e-36 123.6 6.0 4.7e-33 113.6 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO19446.1 - 2.2e-29 102.3 1.6 9e-29 100.4 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Herpes_US9 PF06072.6 EGO19446.1 - 0.017 14.9 0.3 0.031 14.0 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 NmrA PF05368.8 EGO19447.1 - 4.7e-19 68.5 0.0 5.8e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO19447.1 - 2e-08 34.4 0.7 4.8e-08 33.2 0.5 1.8 1 1 0 1 1 1 1 NADH(P)-binding CPSase_L_chain PF00289.17 EGO19447.1 - 4.1e-05 23.6 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain adh_short PF00106.20 EGO19447.1 - 6.6e-05 22.8 0.4 0.00014 21.8 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO19447.1 - 0.0027 17.3 0.1 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO19447.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1949 PF09186.6 EGO19447.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Glyco_trans_1_4 PF13692.1 EGO19448.1 - 6.7e-18 65.1 0.0 1.5e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGO19448.1 - 1.3e-05 24.7 0.0 2.7e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGO19448.1 - 0.00074 19.7 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGO19448.1 - 0.0046 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Nfu_N PF08712.6 EGO19449.1 - 2.1e-30 104.1 0.0 8.6e-30 102.2 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGO19449.1 - 4.1e-22 77.7 0.1 7.1e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain TMEM171 PF15471.1 EGO19450.1 - 0.1 11.3 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 PUF PF00806.14 EGO19452.1 - 1.5e-59 194.1 11.8 6.5e-08 31.6 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EGO19452.1 - 0.0019 18.4 0.1 0.044 14.0 0.0 3.1 2 2 1 3 3 3 1 Protein of unknown function DUF260 Atg14 PF10186.4 EGO19453.1 - 1e-16 60.7 0.0 1.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 VIT1 PF01988.14 EGO19453.1 - 0.26 10.7 0.8 0.42 10.0 0.1 1.6 2 0 0 2 2 2 0 VIT family TBPIP PF07106.8 EGO19453.1 - 0.44 10.0 4.7 0.8 9.2 3.3 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EGO19453.1 - 1.9 7.4 5.8 27 3.6 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Pex14_N PF04695.8 EGO19454.1 - 4.7 7.2 9.0 14 5.7 0.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cullin PF00888.17 EGO19455.1 - 2.7e-08 32.8 0.0 3.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family DUF505 PF04458.7 EGO19455.1 - 0.029 12.5 0.0 0.038 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Phage_Mu_F PF04233.9 EGO19455.1 - 0.038 14.5 0.1 0.066 13.7 0.1 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein Autophagy_N PF03986.8 EGO19455.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain TRAPP PF04051.11 EGO19457.1 - 3.9e-39 133.5 0.0 4.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component VanZ PF04892.7 EGO19457.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 VanZ like family DHO_dh PF01180.16 EGO19458.1 - 1.4e-15 57.0 0.0 4.9e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase HMG_box PF00505.14 EGO19459.1 - 2.6e-12 46.8 0.1 4.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO19459.1 - 0.014 15.7 0.1 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 HMG-box domain 7tm_7 PF08395.7 EGO19460.1 - 0.068 12.1 1.2 0.092 11.7 0.8 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor NICE-3 PF07406.6 EGO19460.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 NICE-3 protein Cortexin PF11057.3 EGO19460.1 - 0.11 12.0 0.2 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Cortexin of kidney PARP PF00644.15 EGO19461.1 - 6.1e-55 185.8 1.4 4e-54 183.1 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGO19461.1 - 2.3e-34 117.9 0.0 3.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGO19461.1 - 4e-20 71.5 0.0 1e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 WGR domain RdRP PF05183.7 EGO19462.1 - 6e-68 229.9 0.0 8.8e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.7 EGO19463.1 - 3.8e-78 263.6 0.0 9.3e-76 255.7 0.0 2.5 1 1 0 1 1 1 1 RNA dependent RNA polymerase TFIIA PF03153.8 EGO19463.1 - 0.056 13.3 12.8 0.085 12.7 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.9 EGO19463.1 - 0.42 10.7 22.3 0.7 10.0 15.5 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Astro_capsid PF03115.9 EGO19463.1 - 0.69 8.0 4.0 0.95 7.6 2.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 EGO19463.1 - 1 7.1 12.8 1.5 6.6 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 EGO19463.1 - 1.9 8.3 9.3 5.2 6.8 6.5 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 EGO19463.1 - 2.9 6.4 17.3 4.3 5.9 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGO19463.1 - 4.3 5.2 12.2 7 4.5 7.2 2.0 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.7 EGO19463.1 - 4.6 6.4 14.1 6.9 5.8 9.8 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.7 EGO19463.1 - 6.6 5.7 14.6 11 5.0 10.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAD_binding_8 PF13450.1 EGO19464.1 - 3.2e-13 49.5 0.0 6.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO19464.1 - 0.011 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EGO19464.1 - 0.017 14.0 0.0 0.034 13.0 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGO19464.1 - 0.061 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EGO19464.1 - 0.12 12.1 0.1 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGO19464.1 - 0.15 11.1 0.2 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family UMP1 PF05348.6 EGO19465.1 - 9e-21 74.1 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.23 EGO19466.1 - 1.3e-22 80.2 0.2 2.3e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EGO19466.1 - 2.7e-18 66.0 0.0 4.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGO19466.1 - 7.8e-05 22.2 0.3 0.00037 20.1 0.1 2.1 2 0 0 2 2 2 1 LisH Fe-S_biosyn PF01521.15 EGO19467.1 - 2.8e-20 72.3 0.0 3.4e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SET PF00856.23 EGO19468.1 - 7.3e-12 45.8 0.1 1.5e-08 35.1 0.0 2.6 3 0 0 3 3 3 2 SET domain SBDS_C PF09377.5 EGO19469.1 - 1.9e-39 134.2 0.7 3.1e-39 133.4 0.1 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EGO19469.1 - 1.1e-33 114.9 2.8 1.8e-33 114.1 1.9 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EGO19469.1 - 0.034 13.8 0.3 0.2 11.3 0.1 2.3 1 1 1 2 2 2 0 Phage XkdN-like protein ComA PF02679.10 EGO19469.1 - 0.035 13.1 0.1 0.056 12.4 0.1 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Myc_N PF01056.13 EGO19469.1 - 0.054 12.6 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NmrA PF05368.8 EGO19470.1 - 8.7e-18 64.4 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO19470.1 - 1.2e-08 35.2 0.4 5.7e-08 32.9 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO19470.1 - 0.0025 17.7 0.3 0.0039 17.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EGO19470.1 - 0.025 14.0 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ABC_tran PF00005.22 EGO19471.1 - 7.3e-45 152.6 0.0 5.2e-21 75.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EGO19471.1 - 5.5e-22 77.4 3.3 5.5e-22 77.4 2.3 2.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EGO19471.1 - 9.1e-17 61.9 7.6 0.00024 21.1 0.1 4.8 3 2 0 5 5 5 4 AAA domain AAA_17 PF13207.1 EGO19471.1 - 1.1e-08 35.8 0.7 0.0041 17.9 0.0 3.6 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.14 EGO19471.1 - 6.5e-08 32.0 0.7 0.034 13.3 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGO19471.1 - 3.2e-07 30.5 1.1 0.061 13.4 0.0 4.0 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGO19471.1 - 4.7e-07 29.2 0.1 0.024 14.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGO19471.1 - 5.9e-07 29.4 0.0 0.023 14.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EGO19471.1 - 7.8e-07 29.4 3.1 0.047 13.9 0.0 4.5 5 0 0 5 5 4 2 AAA domain DUF258 PF03193.11 EGO19471.1 - 1.3e-06 27.7 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EGO19471.1 - 2e-06 28.2 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EGO19471.1 - 2.2e-06 27.4 0.0 0.042 13.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EGO19471.1 - 5.2e-06 26.5 0.0 0.056 13.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGO19471.1 - 1.3e-05 24.1 0.1 0.011 14.5 0.0 2.6 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EGO19471.1 - 4.7e-05 23.1 0.0 0.077 12.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGO19471.1 - 8e-05 22.7 6.2 0.087 12.8 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.18 EGO19471.1 - 0.00017 21.4 0.3 0.36 10.6 0.0 3.0 3 1 0 3 3 2 2 Dynamin family AAA_33 PF13671.1 EGO19471.1 - 0.00066 19.5 0.1 0.24 11.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EGO19471.1 - 0.00091 18.7 4.8 0.28 10.5 0.0 3.5 4 1 0 4 4 3 2 AAA-like domain SbcCD_C PF13558.1 EGO19471.1 - 0.001 18.9 2.4 0.059 13.2 0.1 3.4 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EGO19471.1 - 0.0021 18.1 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EGO19471.1 - 0.0023 17.8 0.0 4.3 7.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGO19471.1 - 0.0025 17.9 0.0 2.4 8.3 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO19471.1 - 0.0059 16.0 1.3 2.4 7.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 EGO19471.1 - 0.0062 16.2 0.1 2.6 7.6 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 EGO19471.1 - 0.0062 16.1 0.1 0.66 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGO19471.1 - 0.0086 15.7 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 NTPase DUF815 PF05673.8 EGO19471.1 - 0.0088 14.9 0.0 0.46 9.3 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) cobW PF02492.14 EGO19471.1 - 0.01 15.3 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EGO19471.1 - 0.01 15.6 0.1 0.01 15.6 0.0 3.7 5 1 0 5 5 4 0 Domain of unknown function DUF87 AAA_5 PF07728.9 EGO19471.1 - 0.018 14.7 0.1 4.5 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGO19471.1 - 0.032 13.7 0.0 4.8 6.6 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EGO19471.1 - 0.044 12.6 0.3 3.5 6.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.1 EGO19471.1 - 0.062 13.6 17.6 0.26 11.5 0.0 4.8 5 0 0 5 5 5 0 AAA domain KAP_NTPase PF07693.9 EGO19471.1 - 0.075 12.0 1.3 0.68 8.8 0.0 2.8 3 1 0 3 3 3 0 KAP family P-loop domain AAA_15 PF13175.1 EGO19471.1 - 0.084 11.9 16.4 0.77 8.7 0.0 5.1 4 2 2 6 6 6 0 AAA ATPase domain Viral_helicase1 PF01443.13 EGO19471.1 - 0.13 11.7 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DNA_topoisoIV PF00521.15 EGO19472.1 - 3.2e-126 421.6 0.2 3.2e-126 421.6 0.1 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGO19472.1 - 7.6e-37 126.1 2.3 2.1e-36 124.7 1.6 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EGO19472.1 - 2.8e-13 49.6 0.0 1.3e-12 47.5 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EGO19472.1 - 1.2e-08 34.6 0.0 6.8e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HrpE PF06188.7 EGO19472.1 - 1.3 8.7 8.9 0.11 12.2 0.8 2.9 4 0 0 4 4 4 0 HrpE/YscL/FliH and V-type ATPase subunit E Rabaptin PF03528.10 EGO19473.1 - 0.00048 20.0 0.3 0.00049 19.9 0.2 1.0 1 0 0 1 1 1 1 Rabaptin Mating_N PF12731.2 EGO19473.1 - 0.11 12.4 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Mating-type protein beta 1 SpoIIID PF12116.3 EGO19473.1 - 0.11 12.4 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Stage III sporulation protein D CCDC92 PF14916.1 EGO19473.1 - 0.13 11.8 0.5 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Oxysterol_BP PF01237.13 EGO19474.1 - 4.8e-87 291.7 0.0 6.1e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DEAD PF00270.24 EGO19475.1 - 5.2e-43 146.4 0.0 1.3e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO19475.1 - 4.4e-27 93.7 0.0 1.7e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGO19475.1 - 0.018 14.1 0.0 0.018 14.1 0.0 2.8 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF3355 PF11835.3 EGO19476.1 - 0.0083 15.9 0.7 0.013 15.3 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3355) DOT1 PF08123.8 EGO19477.1 - 7.7e-64 214.7 0.0 9.5e-64 214.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EGO19477.1 - 9.9e-05 22.8 0.0 0.0002 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO19477.1 - 0.00066 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO19477.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGO19477.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO19477.1 - 0.13 12.7 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Actin PF00022.14 EGO19478.1 - 8.8e-48 162.6 0.0 1.4e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Actin RNA_pol_Rpc4 PF05132.9 EGO19478.1 - 1.9 8.4 9.2 0.86 9.5 0.4 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ras PF00071.17 EGO19479.1 - 1.7e-64 216.0 0.0 2e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO19479.1 - 7.5e-20 71.6 0.0 1.1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO19479.1 - 3.1e-14 52.5 0.1 4e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO19479.1 - 8e-06 25.4 0.1 2e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO19479.1 - 1.4e-05 24.3 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO19479.1 - 0.00027 20.8 0.0 0.00055 19.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO19479.1 - 0.013 14.8 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EGO19479.1 - 0.026 14.5 0.2 0.048 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EGO19479.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 EGO19479.1 - 0.049 12.8 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGO19479.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO19479.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGO19479.1 - 0.08 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EGO19479.1 - 0.094 12.9 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 EGO19479.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 EGO19480.1 - 3.7e-26 92.0 0.0 1.1e-25 90.5 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO19480.1 - 2.4e-11 44.1 0.3 6.4e-05 23.0 0.0 3.0 2 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EGO19480.1 - 9.7e-05 21.5 0.0 0.0072 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EGO19480.1 - 0.00015 22.1 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGO19480.1 - 0.00076 18.7 0.0 0.049 12.8 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EGO19480.1 - 0.0018 18.0 0.0 0.0056 16.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EGO19480.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO19480.1 - 0.0022 18.7 0.0 0.0054 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EGO19480.1 - 0.0027 17.5 0.5 0.0076 16.1 0.0 2.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EGO19480.1 - 0.0041 17.1 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGO19480.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EGO19480.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO19480.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 EGO19480.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 MutS domain V AAA_13 PF13166.1 EGO19480.1 - 0.21 9.9 0.0 0.45 8.9 0.0 1.4 2 0 0 2 2 2 0 AAA domain Nic96 PF04097.9 EGO19481.1 - 1.8e-132 442.5 0.0 2.4e-132 442.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Thiolase_N PF00108.18 EGO19486.1 - 2.7e-07 29.8 0.0 3e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO19486.1 - 9.9e-07 28.2 0.0 9.4e-06 25.0 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGO19486.1 - 1.8e-05 24.3 0.2 0.0018 17.9 0.1 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGO19486.1 - 7.9e-05 22.2 0.6 0.00049 19.6 0.2 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Med9 PF07544.8 EGO19487.1 - 0.00011 21.8 0.1 0.00027 20.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_3 PF13758.1 EGO19487.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit Pkinase PF00069.20 EGO19488.1 - 6.9e-44 149.9 0.0 7.7e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19488.1 - 6.9e-18 64.6 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO19488.1 - 0.00023 20.2 0.0 0.00049 19.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGO19488.1 - 0.083 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_2 PF13923.1 EGO19489.1 - 1.6e-06 28.0 12.4 2.5e-06 27.4 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO19489.1 - 4.2e-06 26.4 10.7 7.6e-06 25.6 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO19489.1 - 4.6e-06 26.1 9.3 8e-06 25.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO19489.1 - 1.4e-05 24.6 10.6 2.3e-05 23.9 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CAP_N PF01213.14 EGO19489.1 - 0.0008 18.7 0.7 0.0011 18.3 0.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal zf-RING_5 PF14634.1 EGO19489.1 - 0.00083 19.0 9.5 0.011 15.4 7.1 2.1 1 1 1 2 2 2 1 zinc-RING finger domain DUF4647 PF15504.1 EGO19489.1 - 0.0018 17.2 0.3 0.0022 16.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) zf-C3HC4_4 PF15227.1 EGO19489.1 - 0.0042 16.9 11.2 0.0077 16.0 7.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGO19489.1 - 0.011 15.5 4.1 0.019 14.7 2.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DRP PF06044.7 EGO19489.1 - 0.054 12.4 1.2 0.09 11.7 0.8 1.3 1 0 0 1 1 1 0 Dam-replacing family zf-rbx1 PF12678.2 EGO19489.1 - 0.11 12.5 8.1 0.66 10.1 5.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGO19489.1 - 0.29 10.9 4.3 1.4 8.6 3.1 2.1 1 1 1 2 2 2 0 RING-type zinc-finger DZR PF12773.2 EGO19489.1 - 0.77 9.6 8.2 2.9 7.7 5.9 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.15 EGO19489.1 - 1.7 8.2 8.0 3.2 7.3 5.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Drf_FH1 PF06346.7 EGO19491.1 - 0.01 15.3 11.4 0.015 14.8 6.2 2.0 2 0 0 2 2 2 1 Formin Homology Region 1 FAD_binding_3 PF01494.14 EGO19493.1 - 2.4e-20 72.9 1.6 5.5e-09 35.5 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGO19493.1 - 6.6e-07 29.2 2.3 1.6e-06 28.0 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO19493.1 - 5.7e-05 23.4 2.1 0.00013 22.2 1.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO19493.1 - 0.00048 18.7 2.8 0.0007 18.1 2.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EGO19493.1 - 0.00049 19.0 3.7 0.0009 18.2 2.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO19493.1 - 0.001 17.8 0.6 0.0052 15.4 0.3 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EGO19493.1 - 0.0016 17.5 0.9 0.0027 16.8 0.6 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO19493.1 - 0.0056 16.5 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGO19493.1 - 0.0082 15.8 2.3 0.015 14.9 1.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EGO19493.1 - 0.019 13.8 1.7 0.031 13.1 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EGO19493.1 - 0.022 14.1 0.4 0.042 13.2 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.5 EGO19493.1 - 0.039 12.7 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase NAD_Gly3P_dh_N PF01210.18 EGO19493.1 - 0.17 11.6 0.3 0.71 9.5 0.2 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EGO19493.1 - 0.18 11.2 0.6 0.33 10.3 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EGO19493.1 - 0.19 10.5 3.6 0.43 9.3 2.2 1.7 2 0 0 2 2 2 0 FAD binding domain F-box-like PF12937.2 EGO19494.1 - 1.1e-06 28.3 2.5 3.3e-06 26.7 1.8 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGO19494.1 - 0.029 14.0 0.3 7.4 6.3 0.0 3.3 3 0 0 3 3 3 0 F-box domain Ribosomal_S14 PF00253.16 EGO19495.1 - 9e-18 63.4 3.4 9.6e-18 63.3 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Toxin_17 PF08086.6 EGO19495.1 - 1.7 8.7 4.2 0.83 9.7 0.3 2.0 1 1 1 2 2 2 0 Ergtoxin family Porphobil_deam PF01379.15 EGO19496.1 - 2.2e-78 262.0 0.0 3.4e-78 261.4 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGO19496.1 - 1.8e-16 59.9 0.6 3.5e-16 59.0 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UQ_con PF00179.21 EGO19497.1 - 1.6e-27 95.6 0.0 2e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO19497.1 - 4.1e-05 23.3 0.0 0.00036 20.2 0.0 1.8 1 1 1 2 2 2 1 Prokaryotic E2 family B UEV PF05743.8 EGO19497.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EGO19497.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.7 1 1 1 2 2 2 0 RWD domain ArsA_ATPase PF02374.10 EGO19498.1 - 9.2e-112 373.0 1.0 1.1e-111 372.8 0.7 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGO19498.1 - 9.8e-16 57.7 0.0 1.5e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGO19498.1 - 1.4e-09 38.0 0.0 3.2e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EGO19498.1 - 1.2e-05 24.6 0.1 3.8e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGO19498.1 - 0.00011 21.7 0.6 0.0017 17.8 0.1 2.5 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EGO19498.1 - 0.00094 18.6 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 EGO19498.1 - 0.0027 17.1 0.6 0.02 14.2 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO19498.1 - 0.0079 15.9 0.0 0.065 12.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain MipZ PF09140.6 EGO19498.1 - 0.0087 15.1 0.1 0.021 13.8 0.1 1.8 1 1 0 1 1 1 1 ATPase MipZ VirC1 PF07015.6 EGO19498.1 - 0.034 13.2 0.1 0.089 11.8 0.1 1.7 1 1 0 1 1 1 0 VirC1 protein PhoH PF02562.11 EGO19498.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 EGO19498.1 - 0.067 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EGO19498.1 - 0.13 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 EGO19499.1 - 0.005 16.7 0.4 0.76 9.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Ku PF02735.11 EGO19500.1 - 3.9e-22 78.6 0.0 7.9e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EGO19500.1 - 4.5e-15 55.6 0.0 8.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EGO19500.1 - 2.2e-09 37.0 0.0 4.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EGO19500.1 - 0.00013 22.0 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO19500.1 - 0.0038 16.9 0.0 0.0086 15.8 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Response_reg PF00072.19 EGO19500.1 - 0.066 13.2 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain SNF2_N PF00176.18 EGO19501.1 - 1.9e-82 276.4 0.3 3.4e-82 275.5 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGO19501.1 - 3.2e-20 71.8 0.0 9.7e-20 70.2 0.0 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 EGO19501.1 - 1.2e-13 50.9 0.5 1.2e-13 50.9 0.3 3.5 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EGO19501.1 - 6.1e-12 45.1 6.7 6.1e-12 45.1 4.6 2.5 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EGO19501.1 - 1.4e-10 40.3 0.0 1.4e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 QLQ Helicase_C PF00271.26 EGO19501.1 - 2.7e-09 36.7 0.1 2.2e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain bZIP_1 PF00170.16 EGO19503.1 - 1.1e-11 44.5 16.1 1.8e-11 43.7 11.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EGO19503.1 - 1e-06 28.7 0.0 1e-06 28.7 0.0 4.7 2 1 1 3 3 1 1 Transcription factor PAP1 bZIP_2 PF07716.10 EGO19503.1 - 8.9e-06 25.4 15.4 8.9e-06 25.4 10.7 1.9 1 1 1 2 2 2 1 Basic region leucine zipper DivIC PF04977.10 EGO19503.1 - 0.00052 19.4 1.5 0.001 18.4 1.1 1.5 1 0 0 1 1 1 1 Septum formation initiator YqgF PF14639.1 EGO19503.1 - 0.058 12.9 1.1 0.11 12.0 0.7 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 DUF972 PF06156.8 EGO19503.1 - 0.065 13.5 0.6 0.14 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC155 PF14662.1 EGO19503.1 - 0.076 12.5 8.7 0.13 11.8 6.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Glutaredoxin2_C PF04399.8 EGO19503.1 - 0.12 11.9 3.3 0.2 11.2 2.3 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TSC22 PF01166.13 EGO19503.1 - 0.18 11.7 3.7 0.53 10.2 2.6 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 EGO19503.1 - 2.1 7.9 6.3 3.5 7.1 4.4 1.2 1 0 0 1 1 1 0 IncA protein Jnk-SapK_ap_N PF09744.4 EGO19503.1 - 3.3 7.6 9.4 5.5 6.9 6.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Erf4 PF10256.4 EGO19506.1 - 1.4e-30 105.5 0.1 1.7e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DnaB_C PF03796.10 EGO19507.1 - 0.022 13.6 0.2 0.028 13.3 0.1 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain 4F5 PF04419.9 EGO19509.1 - 0.001 19.7 27.6 0.2 12.3 19.1 2.5 1 1 0 1 1 1 1 4F5 protein family Fez1 PF06818.10 EGO19509.1 - 0.064 13.2 4.8 0.069 13.1 3.3 1.0 1 0 0 1 1 1 0 Fez1 Selenoprotein_S PF06936.6 EGO19509.1 - 5.1 6.5 8.9 5.6 6.4 6.2 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) U79_P34 PF03064.11 EGO19509.1 - 9.6 5.6 10.0 10 5.5 6.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Brr6_like_C_C PF10104.4 EGO19510.1 - 2.9e-41 140.1 0.2 3.7e-41 139.8 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ATP-synt_8 PF00895.15 EGO19510.1 - 1.1 9.5 4.2 1.7 8.9 0.3 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 CLP_protease PF00574.18 EGO19511.1 - 2e-72 242.6 0.0 2.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Clp protease SAP30_Sin3_bdg PF13867.1 EGO19513.1 - 0.013 15.3 0.3 0.067 13.0 0.1 2.1 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Utp21 PF04192.7 EGO19513.1 - 0.088 11.8 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Chorismate_synt PF01264.16 EGO19514.1 - 5.1e-132 439.5 0.0 7.2e-132 439.0 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase STE3 PF02076.10 EGO19515.1 - 8.1e-70 235.1 17.8 9.6e-70 234.8 12.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4014 PF13198.1 EGO19515.1 - 0.025 14.9 1.9 0.084 13.2 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) Omptin PF01278.15 EGO19516.1 - 0.045 12.8 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Omptin family GST_N_3 PF13417.1 EGO19518.1 - 2.2e-13 50.2 0.1 4e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19518.1 - 3.6e-09 36.4 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO19518.1 - 0.00023 20.9 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO19518.1 - 0.0004 20.4 0.0 0.0012 18.9 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EGO19518.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 EGO19518.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UPF0052 PF01933.13 EGO19519.1 - 8.6e-52 176.3 0.0 1.2e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Glycos_transf_2 PF00535.21 EGO19521.1 - 1.1e-31 109.7 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGO19521.1 - 7.3e-14 52.1 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGO19521.1 - 1.5e-10 40.6 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGO19521.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 21 LSM PF01423.17 EGO19522.1 - 4.7e-10 38.8 0.1 5.8e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sel1 PF08238.7 EGO19523.1 - 7.5e-17 61.3 6.0 9.6e-06 26.0 0.6 4.1 4 0 0 4 4 4 3 Sel1 repeat HA2 PF04408.18 EGO19525.1 - 2.3e-27 94.9 0.0 1.3e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO19525.1 - 5.5e-23 80.9 0.0 1.8e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO19525.1 - 1.2e-13 50.6 0.0 2.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO19525.1 - 0.0028 17.1 0.1 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1546 PF07571.8 EGO19527.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Abhydrolase_6 PF12697.2 EGO19530.1 - 8.1e-25 88.0 0.2 1.4e-24 87.2 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19530.1 - 1e-13 51.4 0.2 6.3e-13 48.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO19530.1 - 3.7e-11 42.9 0.0 6.1e-11 42.2 0.0 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO19530.1 - 3.4e-05 23.5 0.0 6.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 EGO19530.1 - 0.00085 18.0 0.0 0.0012 17.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Ndr PF03096.9 EGO19530.1 - 0.0034 15.9 0.0 0.014 13.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family KfrA_N PF11740.3 EGO19531.1 - 0.025 15.0 5.1 0.031 14.7 3.6 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term GST_C_3 PF14497.1 EGO19531.1 - 0.18 12.2 0.7 1.6 9.2 0.5 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain PBP PF01161.15 EGO19532.1 - 1.1e-17 64.1 0.2 1.9e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3972 PF13118.1 EGO19532.1 - 0.0085 16.1 0.9 0.017 15.1 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) Alpha_kinase PF02816.13 EGO19533.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha-kinase family PepSY_TM_1 PF13172.1 EGO19535.1 - 5.4 6.8 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix Abhydrolase_6 PF12697.2 EGO19536.1 - 5.8e-25 88.5 0.8 7.7e-25 88.0 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19536.1 - 1.1e-13 51.2 0.3 5.3e-13 49.0 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO19536.1 - 1.5e-11 44.2 0.0 2.9e-11 43.3 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO19536.1 - 6.7e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 EGO19536.1 - 0.0019 16.8 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Ndr PF03096.9 EGO19536.1 - 0.018 13.5 0.0 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Chlorophyllase PF07224.6 EGO19536.1 - 0.054 12.2 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase FYVE PF01363.16 EGO19537.1 - 5.8e-17 61.3 3.4 5.8e-17 61.3 2.4 2.0 3 0 0 3 3 3 1 FYVE zinc finger IBR PF01485.16 EGO19537.1 - 0.024 14.5 1.7 0.078 12.8 1.2 1.9 1 0 0 1 1 1 0 IBR domain DUF267 PF03268.9 EGO19539.1 - 0.023 13.5 0.0 0.029 13.2 0.0 1.0 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Speriolin_C PF15059.1 EGO19539.1 - 0.025 14.6 0.1 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Speriolin C-terminus PHD PF00628.24 EGO19540.1 - 1.9e-11 43.4 8.0 3.2e-11 42.7 5.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGO19540.1 - 0.00065 18.9 3.5 0.0011 18.2 2.4 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EGO19540.1 - 0.0012 18.5 3.2 0.0024 17.5 2.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EGO19540.1 - 0.024 13.9 1.1 0.043 13.0 0.7 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-CW PF07496.10 EGO19540.1 - 0.032 13.9 1.8 0.071 12.8 1.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger DNA_methylase PF00145.12 EGO19541.1 - 1.1e-27 97.0 0.0 3.1e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Thiolase_C PF02803.13 EGO19542.1 - 6.8e-07 28.7 0.0 3e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 EGO19542.1 - 1.1e-06 27.8 0.0 1.3e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGO19542.1 - 1.2e-05 24.8 0.0 0.0016 18.0 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGO19542.1 - 6.5e-05 22.5 0.6 0.001 18.6 0.3 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SMN PF06003.7 EGO19543.1 - 0.00014 21.1 6.9 0.0088 15.1 0.1 3.1 3 0 0 3 3 3 2 Survival motor neuron protein (SMN) DUF3773 PF12608.3 EGO19543.1 - 0.029 14.4 1.7 0.04 13.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3773) Ank PF00023.25 EGO19544.1 - 5.9e-07 28.9 0.1 1.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EGO19544.1 - 9.4e-07 29.0 0.0 9.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO19544.1 - 4.2e-06 26.4 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EGO19544.1 - 6.7e-05 23.2 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO19544.1 - 0.00019 21.5 0.1 0.00032 20.8 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF2179 PF10035.4 EGO19545.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Ank_5 PF13857.1 EGO19547.1 - 6.7e-23 80.1 2.4 2.5e-12 46.5 0.3 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO19547.1 - 2.1e-22 79.2 0.0 2.4e-07 30.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO19547.1 - 3.7e-20 71.8 0.5 4.1e-06 27.1 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EGO19547.1 - 3.9e-19 67.4 2.5 9.4e-07 28.3 0.2 5.7 5 2 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 EGO19547.1 - 7.1e-13 47.4 1.9 0.0022 18.0 0.1 5.8 5 2 0 5 5 5 3 Ankyrin repeat RSD-2 PF07547.8 EGO19547.1 - 0.054 13.6 0.2 3.2 7.9 0.0 2.6 2 1 1 3 3 3 0 RSD-2 N-terminal domain DUF4149 PF13664.1 EGO19552.1 - 7.6 6.6 17.7 19 5.4 6.4 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Pex14_N PF04695.8 EGO19554.1 - 0.034 14.1 8.1 0.036 14.0 5.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDE_Tnp_4 PF13359.1 EGO19555.1 - 5.4e-07 29.3 0.0 7.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cys_rich_VLP PF14194.1 EGO19555.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich VLP Amino_oxidase PF01593.19 EGO19556.1 - 0.14 11.1 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF287 PF03384.9 EGO19557.1 - 0.16 12.1 0.3 0.19 11.9 0.1 1.4 1 1 0 1 1 1 0 Drosophila protein of unknown function, DUF287 RbsD_FucU PF05025.8 EGO19558.1 - 0.051 13.8 0.9 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 RbsD / FucU transport protein family NfeD PF01957.13 EGO19560.1 - 4.9 7.2 13.7 11 6.1 1.1 3.2 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding Cation_ATPase_C PF00689.16 EGO19560.1 - 6.7 6.1 19.1 3.6 7.0 7.1 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Syndecan PF01034.15 EGO19561.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain RTA1 PF04479.8 EGO19562.1 - 7.7e-39 133.4 2.0 1.4e-38 132.5 1.4 1.3 1 0 0 1 1 1 1 RTA1 like protein DHFR_1 PF00186.14 EGO19563.1 - 1.2e-32 112.6 0.0 2e-32 112.0 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase DUF4111 PF13427.1 EGO19569.1 - 0.0034 17.1 0.3 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4111) DUF552 PF04472.7 EGO19569.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Syndecan PF01034.15 EGO19570.1 - 0.011 15.3 0.1 0.027 14.1 0.1 1.7 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EGO19570.1 - 0.022 13.5 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PDGLE PF13190.1 EGO19570.1 - 0.085 12.5 1.9 0.26 11.0 1.3 1.8 1 1 0 1 1 1 0 PDGLE domain EphA2_TM PF14575.1 EGO19570.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.2 EGO19571.1 - 1.1e-08 34.5 0.6 3.3e-08 33.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EGO19572.1 - 1.6e-06 27.6 0.7 5.4e-06 26.0 0.5 2.0 1 0 0 1 1 1 1 F-box-like PCI PF01399.22 EGO19573.1 - 1.6e-07 31.5 1.0 6.2e-07 29.6 0.7 2.0 1 1 0 1 1 1 1 PCI domain MitMem_reg PF13012.1 EGO19573.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Rgp1 PF08737.5 EGO19574.1 - 4.5e-51 174.2 0.0 7.1e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EGO19574.1 - 0.06 13.1 0.2 4 7.2 0.0 2.9 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain PSP1 PF04468.7 EGO19575.1 - 2.8e-32 110.5 0.9 4.3e-32 109.9 0.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-Apc11 PF12861.2 EGO19576.1 - 1.1e-40 137.3 10.1 1.3e-40 137.0 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGO19576.1 - 1.5e-31 108.3 9.5 2e-31 107.8 6.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGO19576.1 - 1.3e-05 24.9 16.0 5.2e-05 22.9 11.0 2.2 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGO19576.1 - 0.0043 16.7 10.4 0.039 13.6 7.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EGO19576.1 - 0.065 12.7 2.7 0.11 11.9 1.8 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EGO19576.1 - 0.1 12.6 11.0 0.38 10.8 7.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO19576.1 - 0.15 11.7 13.5 0.79 9.4 9.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4219 PF13961.1 EGO19579.1 - 0.0021 17.4 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EGO19579.1 - 0.056 13.0 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO19580.1 - 0.0019 17.7 0.4 0.0083 15.6 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type LRR19-TM PF15176.1 EGO19582.1 - 0.0059 16.2 0.4 0.0083 15.8 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Helicase_C PF00271.26 EGO19583.1 - 6.1e-10 38.8 0.0 7.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_17 PF13207.1 EGO19584.1 - 1.4e-05 25.9 0.0 5.5e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO19584.1 - 0.00055 20.2 0.2 0.0076 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGO19584.1 - 0.0031 16.6 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGO19584.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGO19584.1 - 0.045 13.7 0.1 0.17 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain GST_N_3 PF13417.1 EGO19585.1 - 1.2e-09 38.2 0.0 4.4e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19585.1 - 5.1e-08 32.8 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO19585.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO19585.1 - 0.00015 21.8 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO19585.1 - 0.0043 16.9 0.2 0.0088 15.9 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO19585.1 - 0.054 13.9 0.2 0.15 12.5 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bromodomain PF00439.20 EGO19587.1 - 1.4e-21 76.2 0.0 2.2e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EGO19587.1 - 4.1e-08 32.9 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 BAH domain TFIIF_alpha PF05793.7 EGO19588.1 - 0.015 13.6 17.5 0.016 13.6 12.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp11 PF03998.8 EGO19588.1 - 0.019 14.7 7.2 0.022 14.5 5.0 1.0 1 0 0 1 1 1 0 Utp11 protein EAP30 PF04157.11 EGO19588.1 - 0.041 13.0 3.7 0.056 12.5 2.6 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family MDM1 PF15501.1 EGO19588.1 - 0.1 11.5 10.8 0.11 11.3 7.5 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 PGA2 PF07543.7 EGO19588.1 - 0.22 11.2 5.8 0.27 11.0 4.0 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Sporozoite_P67 PF05642.6 EGO19588.1 - 1.2 6.9 10.8 1.3 6.7 7.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 EGO19588.1 - 1.4 8.5 10.6 1.7 8.2 7.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EGO19588.1 - 2.1 6.2 14.0 2.4 6.0 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 EGO19588.1 - 2.7 7.0 6.3 3 6.9 4.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 EGO19588.1 - 5.6 6.2 16.3 6.7 6.0 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 EGO19588.1 - 7.6 5.5 13.9 9.1 5.3 9.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 EGO19588.1 - 7.9 4.4 10.4 8.6 4.3 7.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Chs3p PF12271.3 EGO19589.1 - 1.4e-116 388.5 19.9 1.6e-116 388.3 13.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit A_deaminase PF00962.17 EGO19590.1 - 8.2e-23 80.8 0.0 1.6e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase adh_short PF00106.20 EGO19591.1 - 1.4e-31 109.6 2.1 1.9e-31 109.2 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO19591.1 - 1.8e-22 80.2 1.3 7.2e-22 78.3 0.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO19591.1 - 5.9e-15 55.3 0.6 9.2e-15 54.7 0.4 1.2 1 0 0 1 1 1 1 KR domain RRF PF01765.14 EGO19592.1 - 0.051 13.0 0.8 0.055 12.9 0.6 1.1 1 0 0 1 1 1 0 Ribosome recycling factor RecX PF02631.11 EGO19592.1 - 0.056 13.6 1.9 0.071 13.3 1.3 1.1 1 0 0 1 1 1 0 RecX family Orexin_rec2 PF03827.8 EGO19592.1 - 0.068 13.2 0.3 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 Orexin receptor type 2 CCDC-167 PF15188.1 EGO19592.1 - 0.094 12.6 2.3 0.14 12.1 1.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spore_II_R PF09551.5 EGO19592.1 - 0.25 11.3 1.9 0.68 9.9 1.3 1.7 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF2664 PF10867.3 EGO19592.1 - 0.47 11.0 5.0 3.9 8.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Rtf2 PF04641.7 EGO19598.1 - 1.7e-71 240.4 0.2 2.2e-71 240.1 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EGO19598.1 - 0.00072 19.2 0.1 0.0068 16.1 0.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EGO19598.1 - 0.0078 15.7 1.1 0.13 11.8 0.0 2.6 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EGO19598.1 - 0.035 13.9 0.1 0.13 12.0 0.1 2.0 1 1 1 2 2 2 0 Ring finger domain MMR_HSR1 PF01926.18 EGO19599.1 - 1.8e-08 34.3 0.0 2.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO19599.1 - 6.9e-07 28.5 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 EGO19599.1 - 2e-05 24.0 0.0 0.00015 21.1 0.0 2.0 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 EGO19599.1 - 9.6e-05 22.2 0.5 0.00026 20.8 0.2 1.7 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EGO19599.1 - 9.6e-05 22.8 0.0 0.00018 21.9 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EGO19599.1 - 0.00014 21.4 0.0 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EGO19599.1 - 0.00071 19.6 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EGO19599.1 - 0.0033 17.7 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EGO19599.1 - 0.0077 15.7 0.2 0.016 14.6 0.1 1.5 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EGO19599.1 - 0.0083 15.3 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 EGO19599.1 - 0.014 14.2 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IIGP PF05049.8 EGO19599.1 - 0.024 13.4 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EGO19599.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO19599.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO19599.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EGO19599.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.9 EGO19599.1 - 0.2 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.18 EGO19600.1 - 4e-06 26.7 0.0 6.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO19600.1 - 4.9e-06 25.8 0.0 7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGO19600.1 - 8e-05 23.1 0.0 0.00014 22.3 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EGO19600.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO19600.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGO19600.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EGO19600.1 - 0.014 14.8 0.1 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EGO19600.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO19600.1 - 0.022 15.0 0.0 0.057 13.7 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EGO19600.1 - 0.023 14.2 0.1 0.059 12.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EGO19600.1 - 0.026 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EGO19600.1 - 0.04 13.7 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EGO19600.1 - 0.042 13.6 0.6 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Dynamin family Ras PF00071.17 EGO19600.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 Ras family AAA_17 PF13207.1 EGO19600.1 - 0.062 14.1 0.1 0.096 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EGO19600.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EGO19600.1 - 0.11 12.7 1.2 0.38 11.0 0.3 1.9 2 0 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.10 EGO19601.1 - 1.3e-75 253.1 0.0 1.2e-73 246.7 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase OPT PF03169.10 EGO19602.1 - 7.3e-187 622.5 66.1 8.4e-187 622.3 45.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydrophobin PF01185.13 EGO19603.1 - 4.9e-21 74.9 8.9 6e-21 74.6 6.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EGO19604.1 - 4.9e-21 74.9 8.9 6e-21 74.6 6.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin ChaC PF04752.7 EGO19605.1 - 7.8e-53 179.0 0.0 8.9e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF21 PF01595.15 EGO19606.1 - 6e-31 107.1 0.6 1.1e-30 106.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGO19606.1 - 1.1e-08 34.7 0.4 0.003 17.3 0.0 3.3 3 0 0 3 3 3 2 CBS domain tRNA_U5-meth_tr PF05958.6 EGO19607.1 - 8.3e-16 57.6 0.0 3.8e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGO19607.1 - 8.6e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGO19607.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGO19607.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO19607.1 - 0.00022 21.7 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EGO19607.1 - 0.0016 18.1 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 EGO19607.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EGO19607.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EGO19607.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 Met-10+ like-protein TRM PF02005.11 EGO19607.1 - 0.18 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Aminotran_4 PF01063.14 EGO19608.1 - 2.3e-24 86.1 0.0 3.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Alpha-amylase PF00128.19 EGO19609.1 - 7.4e-65 219.4 0.2 1.4e-64 218.4 0.2 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EGO19609.1 - 6.4e-12 45.3 1.6 8.5e-12 45.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) adh_short PF00106.20 EGO19610.1 - 8.1e-07 29.1 0.5 1.3e-06 28.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGO19610.1 - 4.2e-05 23.6 0.2 5.5e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EGO19610.1 - 0.0049 16.9 0.2 0.0066 16.5 0.2 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EGO19610.1 - 0.0071 16.0 0.4 0.01 15.4 0.3 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EGO19610.1 - 0.0071 15.3 0.2 0.0085 15.1 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 EGO19610.1 - 0.0098 14.9 0.1 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EGO19610.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGO19610.1 - 0.024 13.5 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EGO19610.1 - 0.028 14.2 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 EGO19610.1 - 0.051 12.4 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.13 EGO19610.1 - 0.12 12.0 0.3 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank PF00023.25 EGO19611.1 - 7.1e-11 41.3 0.1 6.5e-09 35.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EGO19611.1 - 1.6e-10 41.1 0.1 7.5e-05 23.1 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO19611.1 - 8.8e-10 38.7 0.2 1.9e-07 31.2 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO19611.1 - 1.9e-07 30.6 0.1 1.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGO19611.1 - 5.3e-07 29.6 0.1 3.3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO19612.1 - 7.1e-26 90.1 0.0 3.5e-08 33.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO19612.1 - 5.6e-25 86.8 0.0 5e-09 36.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO19612.1 - 4e-24 84.7 0.0 3.1e-14 53.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO19612.1 - 1.5e-22 78.2 0.0 9e-07 28.3 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGO19612.1 - 9.6e-16 56.3 0.0 0.00017 21.4 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat SCHIP-1 PF10148.4 EGO19612.1 - 0.046 13.1 0.1 7.3 5.9 0.0 2.8 4 0 0 4 4 4 0 Schwannomin-interacting protein 1 Endonuc-FokI_C PF09254.6 EGO19612.1 - 0.065 12.3 0.0 0.22 10.5 0.0 1.7 1 1 1 2 2 2 0 Restriction endonuclease FokI, C terminal PsbJ PF01788.12 EGO19612.1 - 0.067 12.7 0.0 0.76 9.3 0.0 2.5 3 0 0 3 3 3 0 PsbJ DUF2075 PF09848.4 EGO19613.1 - 0.00069 18.6 0.0 0.0025 16.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EGO19613.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EGO19613.1 - 0.0068 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EGO19613.1 - 0.011 16.5 0.0 0.22 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO19613.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGO19613.1 - 0.021 13.6 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EGO19613.1 - 0.037 14.2 0.0 0.092 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EGO19613.1 - 0.04 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EGO19613.1 - 0.054 13.1 0.0 0.16 11.5 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EGO19613.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGO19613.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO19613.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EGO19613.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DHC_N1 PF08385.7 EGO19614.1 - 6.3e-184 612.5 3.1 3e-182 607.0 0.2 2.4 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DUF4381 PF14316.1 EGO19616.1 - 0.069 13.2 0.4 0.076 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) G-alpha PF00503.15 EGO19618.1 - 8.7e-108 360.4 0.1 1.1e-107 360.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO19618.1 - 1.5e-12 47.1 1.1 7.3e-08 31.8 0.4 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGO19618.1 - 0.00084 19.8 0.0 0.57 10.6 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EGO19618.1 - 0.019 14.9 0.1 10 6.1 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO19618.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGO19618.1 - 0.082 12.3 0.2 10 5.5 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EGO19618.1 - 0.1 11.9 0.0 9.3 5.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 EGO19618.1 - 0.45 9.6 7.2 2.4 7.2 0.8 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region WD40 PF00400.27 EGO19619.1 - 1.6e-14 53.1 0.1 0.082 12.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF2415 PF10313.4 EGO19619.1 - 0.016 14.8 0.0 0.053 13.1 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SPO22 PF08631.5 EGO19621.1 - 1.2e-07 31.1 0.9 2.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like Apc3 PF12895.2 EGO19621.1 - 0.013 15.6 2.1 0.017 15.2 1.0 1.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 APC8 PF04049.8 EGO19621.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 EGO19621.1 - 0.094 12.6 2.0 6.4 6.9 0.2 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Gp5_OB PF06714.6 EGO19623.1 - 0.024 14.6 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Gp5 N-terminal OB domain Rick_17kDa_Anti PF05433.10 EGO19623.1 - 0.094 12.3 2.1 0.18 11.4 1.3 1.7 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EGO19623.1 - 0.099 12.2 1.2 0.24 11.0 0.8 1.6 1 1 1 2 2 2 0 Glycine zipper Caa3_CtaG PF09678.5 EGO19623.1 - 0.13 11.2 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Cyclin PF08613.6 EGO19624.1 - 1.3e-17 64.6 0.0 2.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGO19624.1 - 7.3e-09 35.2 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RicinB_lectin_2 PF14200.1 EGO19628.1 - 1e-05 25.8 0.7 0.13 12.6 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Cullin PF00888.17 EGO19629.1 - 1.3e-112 377.3 1.3 1.6e-112 377.0 0.9 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGO19629.1 - 1.6e-21 75.8 0.0 4.6e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Lipase_GDSL_2 PF13472.1 EGO19630.1 - 1.4e-10 41.5 0.0 1.9e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO19630.1 - 5.2e-08 33.0 0.0 9.6e-07 28.8 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase APH PF01636.18 EGO19631.1 - 6e-08 32.7 0.3 4.1e-07 29.9 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGO19631.1 - 0.085 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase 4HBT PF03061.17 EGO19633.1 - 3e-10 40.0 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGO19633.1 - 0.0043 16.8 0.5 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase-like superfamily PRCC PF10253.4 EGO19636.1 - 0.018 15.7 1.9 0.024 15.3 1.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CCDC66 PF15236.1 EGO19636.1 - 0.027 14.1 5.4 0.019 14.6 2.7 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Utp14 PF04615.8 EGO19636.1 - 0.088 10.9 4.5 0.098 10.8 3.1 1.1 1 0 0 1 1 1 0 Utp14 protein PBP PF01161.15 EGO19638.1 - 4.6e-26 91.4 0.3 5.4e-26 91.1 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_C14 PF00656.17 EGO19641.1 - 8.7e-66 222.1 0.0 1.2e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Pkinase_Tyr PF07714.12 EGO19642.1 - 3.4e-28 98.4 0.0 5.6e-28 97.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO19642.1 - 1.8e-25 89.5 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGO19642.1 - 0.00026 20.0 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Methyltransf_25 PF13649.1 EGO19644.1 - 1.1e-08 35.3 0.0 2.8e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO19644.1 - 0.0015 19.1 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO19644.1 - 0.0064 16.9 0.0 0.0095 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO19644.1 - 0.026 15.0 0.0 0.077 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGO19644.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pinin_SDK_N PF04697.8 EGO19645.1 - 0.013 15.4 4.5 0.026 14.5 3.0 1.6 1 1 0 1 1 1 0 pinin/SDK conserved region GATase_4 PF13230.1 EGO19647.1 - 7e-24 83.9 0.0 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 EGO19647.1 - 8.8e-10 37.8 0.0 4.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGO19647.1 - 1.6e-09 37.8 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain ClpS PF02617.12 EGO19648.1 - 8.5e-09 35.0 0.2 1.9e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 EGO19648.1 - 0.0089 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL zf-UBR PF02207.15 EGO19648.1 - 0.29 10.8 16.9 0.025 14.2 0.4 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) tRNA-synt_1c PF00749.16 EGO19649.1 - 2.6e-82 275.9 0.0 3.6e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF3663 PF12404.3 EGO19649.1 - 0.049 13.4 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Peptidase DNA_repr_REX1B PF14966.1 EGO19649.1 - 0.089 13.1 0.7 1.3 9.4 0.1 2.5 2 1 0 2 2 2 0 DNA repair REX1-B Pkinase PF00069.20 EGO19650.1 - 3.8e-15 55.7 0.0 3.4e-13 49.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.18 EGO19650.1 - 0.0045 16.7 0.2 0.24 11.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGO19650.1 - 0.0075 15.3 0.4 0.016 14.2 0.2 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO19651.1 - 5e-15 55.3 0.0 7.3e-13 48.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19651.1 - 0.00017 20.7 0.3 0.00057 19.0 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TRAPP PF04051.11 EGO19652.1 - 2.7e-30 104.8 0.0 3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4305 PF14146.1 EGO19653.1 - 0.09 12.5 1.6 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) Cytochrom_B561 PF03188.11 EGO19653.1 - 0.49 10.2 6.4 0.27 11.0 0.3 2.6 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 p450 PF00067.17 EGO19655.1 - 7e-29 100.6 0.0 1.1e-27 96.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF983 PF06170.7 EGO19656.1 - 0.71 10.0 0.0 0.71 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) LysM PF01476.15 EGO19657.1 - 4.6e-18 64.8 0.3 2e-08 33.9 0.1 2.3 2 0 0 2 2 2 2 LysM domain DUF2612 PF11041.3 EGO19657.1 - 0.053 13.0 0.2 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2612) 2-oxoacid_dh PF00198.18 EGO19658.1 - 5.9e-52 176.2 0.0 1.6e-51 174.8 0.0 1.7 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGO19658.1 - 1.3e-19 69.5 0.3 2.4e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGO19658.1 - 1.1e-10 40.9 0.0 2.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGO19658.1 - 2.7e-05 23.7 1.1 9.2e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EGO19658.1 - 0.0086 16.4 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 EGO19658.1 - 0.023 13.8 0.1 0.035 13.2 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein HlyD PF00529.15 EGO19658.1 - 0.071 12.4 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Pkinase PF00069.20 EGO19659.1 - 4.5e-06 26.0 0.0 0.00043 19.5 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Glucosamine_iso PF01182.15 EGO19661.1 - 1.2e-21 77.4 0.0 2.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SIR2 PF02146.12 EGO19662.1 - 3.6e-33 114.7 0.0 5.7e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TypeIII_RM_meth PF12564.3 EGO19662.1 - 0.19 11.7 0.2 0.43 10.5 0.1 1.5 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit LysM PF01476.15 EGO19664.1 - 2.6e-15 56.0 2.1 1.8e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain F-box-like PF12937.2 EGO19665.1 - 1.2e-08 34.4 0.9 4.1e-08 32.8 0.6 2.0 1 0 0 1 1 1 1 F-box-like ERCC4 PF02732.10 EGO19667.1 - 8e-27 93.7 0.0 1.8e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain FTCD_C PF04961.7 EGO19667.1 - 0.07 12.5 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Prominin PF05478.6 EGO19667.1 - 0.097 10.1 0.1 0.14 9.6 0.1 1.1 1 0 0 1 1 1 0 Prominin HTH_38 PF13936.1 EGO19668.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Alpha-amylase PF00128.19 EGO19670.1 - 9.2e-96 320.9 2.4 1.3e-95 320.4 1.7 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DSPc PF00782.15 EGO19671.1 - 1.4e-07 31.1 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO19671.1 - 1.9e-06 27.9 0.0 5.6e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGO19671.1 - 1.2e-05 25.5 0.1 0.0081 16.4 0.1 2.1 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO19671.1 - 3.1e-05 23.4 0.0 3.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EGO19671.1 - 4e-05 23.1 0.0 5.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 EGO19671.1 - 0.045 13.1 0.0 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family F-box PF00646.28 EGO19672.1 - 3.9e-05 23.1 0.5 8.6e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO19672.1 - 0.0042 16.7 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 F-box-like DUF3752 PF12572.3 EGO19674.1 - 1.9e-31 109.2 11.9 1.9e-31 109.2 8.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Nucleo_P87 PF07267.6 EGO19674.1 - 1.9 7.0 7.5 3.1 6.3 5.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LysM PF01476.15 EGO19677.1 - 1.2e-14 53.9 0.2 4.1e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 LysM domain Myb_DNA-bind_4 PF13837.1 EGO19678.1 - 0.035 14.2 0.1 0.24 11.5 0.0 2.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Acetyltransf_8 PF13523.1 EGO19680.1 - 0.00022 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO19680.1 - 0.038 14.1 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO19680.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Polysacc_deac_2 PF04748.8 EGO19682.1 - 0.037 13.0 0.5 4.2 6.3 0.0 2.2 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase CCDC74_C PF14917.1 EGO19682.1 - 0.058 13.4 0.1 0.067 13.2 0.1 1.3 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal p450 PF00067.17 EGO19683.1 - 4.1e-70 236.5 0.0 5.1e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 EGO19684.1 - 8.4e-33 113.6 15.7 9.9e-33 113.4 10.9 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family TMEM89 PF15098.1 EGO19684.1 - 0.089 12.8 0.7 0.21 11.6 0.5 1.5 1 0 0 1 1 1 0 TMEM89 protein family NmrA PF05368.8 EGO19686.1 - 2e-42 145.0 0.0 2.3e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO19686.1 - 6.3e-16 58.9 0.0 8.6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO19686.1 - 2e-05 23.4 0.0 3.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO19686.1 - 0.00096 18.6 0.1 0.0019 17.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGO19686.1 - 0.013 15.5 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 EGO19686.1 - 0.021 15.1 0.2 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 EGO19687.1 - 3.7e-61 206.5 0.0 4.5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19687.1 - 4.9e-27 94.6 0.0 5.7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO19687.1 - 5.3e-07 28.8 0.0 1.3e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO19687.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO19687.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pectate_lyase_3 PF12708.2 EGO19688.1 - 3.8e-81 272.4 24.4 4.8e-66 223.1 7.1 3.8 3 1 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO19688.1 - 6.7e-08 31.8 1.7 0.0056 16.1 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase p450 PF00067.17 EGO19689.1 - 4e-66 223.4 0.0 4.7e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGO19691.1 - 8.6e-11 41.4 0.0 3.7e-09 36.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19691.1 - 0.0043 16.1 0.1 0.014 14.5 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase DUF648 PF04890.8 EGO19692.1 - 0.081 12.0 0.8 0.11 11.6 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Epimerase PF01370.16 EGO19693.1 - 2.2e-18 66.5 0.0 7.4e-18 64.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO19693.1 - 4.8e-15 54.9 0.0 8.4e-15 54.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO19693.1 - 9.2e-15 55.1 0.5 2.5e-14 53.7 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO19693.1 - 1.7e-08 33.7 0.0 4.7e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGO19693.1 - 2.3e-06 27.6 1.0 1.7e-05 24.7 0.2 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EGO19693.1 - 6.2e-06 25.6 0.4 5e-05 22.6 0.2 2.1 1 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EGO19693.1 - 0.00031 19.7 0.1 0.00044 19.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EGO19693.1 - 0.0046 16.6 0.2 0.061 12.9 0.1 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO19694.1 - 8.6e-20 71.1 0.1 1.4e-19 70.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO19694.1 - 1.2e-13 50.4 0.1 2e-13 49.6 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO19694.1 - 4.5e-11 43.0 0.4 1.3e-10 41.5 0.2 1.9 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO19694.1 - 2.3e-10 39.8 0.1 6.6e-10 38.3 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGO19694.1 - 5.5e-07 29.6 0.4 3.2e-06 27.1 0.0 2.4 2 2 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO19694.1 - 2.8e-06 26.4 0.1 3.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGO19694.1 - 3.7e-05 23.0 0.3 0.0003 20.1 0.1 2.0 1 1 1 2 2 2 1 NmrA-like family KR PF08659.5 EGO19694.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.6 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 EGO19695.1 - 3.8e-39 134.3 19.6 3.8e-39 134.3 13.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO19695.1 - 9.5e-19 67.2 3.2 9.5e-19 67.2 2.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.6 EGO19695.1 - 4.1e-05 23.2 2.9 0.0024 17.6 0.2 3.1 2 0 0 2 2 2 2 Membrane bound YbgT-like protein p450 PF00067.17 EGO19696.1 - 4.4e-71 239.7 0.0 5.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO19697.1 - 3.7e-69 233.4 0.0 4.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EGO19698.1 - 8.5e-20 71.3 0.3 1.9e-15 57.2 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pectate_lyase_3 PF12708.2 EGO19699.1 - 1e-71 241.6 12.6 1.9e-55 188.4 5.6 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO19699.1 - 7.2e-08 31.7 0.5 0.003 16.9 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Retrotrans_gag PF03732.12 EGO19703.1 - 1.4e-06 28.2 3.4 1.8e-06 27.9 1.2 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO19703.1 - 9.5e-06 25.3 1.9 1.7e-05 24.4 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO19703.1 - 0.43 10.2 1.7 1.1 9.0 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Chromo PF00385.19 EGO19704.1 - 5e-07 29.3 0.0 1.7e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SR-25 PF10500.4 EGO19704.1 - 0.0011 18.5 10.4 0.0017 17.8 7.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein YL1 PF05764.8 EGO19704.1 - 0.005 16.4 19.5 0.0083 15.7 13.5 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Nop53 PF07767.6 EGO19704.1 - 0.012 14.6 11.3 0.02 13.8 7.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RepB-RCR_reg PF10723.4 EGO19704.1 - 0.055 13.1 2.4 0.14 11.9 1.7 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB CDC45 PF02724.9 EGO19704.1 - 0.099 10.6 15.3 0.13 10.2 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGO19704.1 - 0.55 8.0 18.6 0.15 9.9 10.9 1.4 2 0 0 2 2 2 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EGO19704.1 - 0.66 9.6 21.8 1.1 8.9 15.1 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.7 EGO19704.1 - 2.4 6.1 13.1 3.8 5.4 9.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.5 EGO19704.1 - 2.9 6.8 23.2 4.9 6.0 16.1 1.3 1 0 0 1 1 1 0 BUD22 Herpes_DNAp_acc PF04929.7 EGO19704.1 - 3.5 6.4 7.8 4.9 6.0 5.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PepSY_TM_1 PF13172.1 EGO19705.1 - 4.7 7.0 7.3 0.85 9.4 1.8 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix Epimerase PF01370.16 EGO19708.1 - 2.6e-18 66.3 0.1 3.9e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO19708.1 - 2e-15 57.2 0.3 4.7e-15 56.0 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO19708.1 - 3.3e-12 45.6 0.0 4.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGO19708.1 - 1.3e-08 34.0 0.1 2.9e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EGO19708.1 - 1.9e-06 27.3 0.0 6.1e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EGO19708.1 - 2.2e-05 24.4 0.2 0.00015 21.7 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO19708.1 - 0.011 15.4 0.2 0.11 12.1 0.1 2.2 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EGO19708.1 - 0.011 14.6 0.1 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LRR_8 PF13855.1 EGO19709.1 - 0.029 14.0 0.9 0.99 9.2 0.2 3.0 2 1 1 3 3 3 0 Leucine rich repeat Phosducin PF02114.11 EGO19710.1 - 1.2e-18 66.8 0.0 9e-09 34.4 0.0 3.1 2 1 1 3 3 3 3 Phosducin MFS_1 PF07690.11 EGO19711.1 - 1.7e-11 43.4 62.0 4.9e-08 32.0 26.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily SAE2 PF08573.5 EGO19712.1 - 6.5e-19 68.4 1.5 1.6e-18 67.1 1.0 1.7 1 1 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TMF_TATA_bd PF12325.3 EGO19713.1 - 0.0044 16.7 0.4 0.0044 16.7 0.3 1.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.12 EGO19713.1 - 0.067 13.4 0.7 0.067 13.4 0.5 1.8 2 1 0 2 2 2 0 bZIP Maf transcription factor FlxA PF14282.1 EGO19713.1 - 0.078 12.9 0.6 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 FlxA-like protein Reo_sigmaC PF04582.7 EGO19713.1 - 0.085 12.0 0.1 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cep57_MT_bd PF06657.8 EGO19713.1 - 0.09 12.7 0.6 0.09 12.7 0.4 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 EGO19713.1 - 0.096 12.5 0.9 0.11 12.4 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2205 PF10224.4 EGO19713.1 - 0.1 12.2 0.3 0.55 9.8 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Spc24 PF08286.6 EGO19713.1 - 0.15 11.7 1.5 0.26 10.9 1.1 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Viral_P18 PF04521.8 EGO19713.1 - 0.16 11.4 0.6 0.27 10.6 0.4 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF972 PF06156.8 EGO19713.1 - 0.19 12.1 1.0 0.72 10.2 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DMAP1 PF05499.7 EGO19713.1 - 0.57 9.6 2.8 0.99 8.9 0.1 2.0 1 1 1 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF4449 PF14613.1 EGO19714.1 - 1.5e-24 86.7 4.5 1.5e-24 86.7 3.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Tom22 PF04281.8 EGO19714.1 - 4.3 6.8 9.0 0.11 11.9 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 UPF0047 PF01894.12 EGO19715.1 - 8.2e-41 138.5 0.1 9.3e-41 138.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CCCH PF00642.19 EGO19716.1 - 6e-19 67.2 21.4 4.9e-05 22.9 0.4 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 EGO19716.1 - 0.00016 21.4 4.2 0.00069 19.4 2.9 2.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO19716.1 - 0.001 18.7 0.1 0.0027 17.3 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 EGO19716.1 - 0.052 13.5 28.2 0.084 12.9 0.4 5.5 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type BRF1 PF07741.8 EGO19718.1 - 4.6 7.5 6.9 50 4.2 4.9 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LcrG PF07216.7 EGO19720.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 LcrG protein NmrA PF05368.8 EGO19722.1 - 5.1e-29 101.1 0.0 5.9e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO19722.1 - 2e-08 34.4 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO19722.1 - 1.1e-06 27.5 0.0 1.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGO19723.1 - 6.4e-48 163.0 0.1 7.7e-48 162.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO19723.1 - 3.5e-16 59.7 0.2 4.8e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO19723.1 - 1.1e-11 43.9 0.1 5.5e-09 35.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO19723.1 - 0.00012 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EGO19723.1 - 0.0029 17.8 0.1 0.0055 16.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EGO19723.1 - 0.007 16.3 0.5 0.013 15.4 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EGO19723.1 - 0.014 15.3 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain KR PF08659.5 EGO19723.1 - 0.017 14.8 0.2 0.04 13.5 0.1 1.6 2 0 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EGO19723.1 - 0.078 11.9 0.3 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Cir_N PF10197.4 EGO19724.1 - 0.00073 19.5 0.0 0.00073 19.5 0.0 3.0 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 EGO19724.1 - 0.36 11.3 5.4 0.3 11.5 0.3 2.5 2 0 0 2 2 2 0 Pre-mRNA splicing factor Pectate_lyase_3 PF12708.2 EGO19725.1 - 1.3e-80 270.7 23.9 1.2e-64 218.5 5.9 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO19725.1 - 1.5e-06 27.5 6.5 0.0076 15.6 0.2 3.1 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase p450 PF00067.17 EGO19726.1 - 1.3e-66 224.9 0.0 1.6e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO19727.1 - 2.2e-67 227.5 0.0 3.2e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Dec-1 PF04624.9 EGO19727.1 - 0.14 11.8 1.2 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Dec-1 repeat TT_ORF2 PF02957.10 EGO19729.1 - 0.077 13.6 0.8 0.23 12.1 0.6 1.8 1 0 0 1 1 1 0 TT viral ORF2 DEAD PF00270.24 EGO19730.1 - 2.9e-42 144.0 0.0 5.3e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO19730.1 - 6.8e-22 77.1 0.0 1.3e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGO19730.1 - 1.1e-20 72.9 0.6 3.5e-20 71.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Pkinase PF00069.20 EGO19731.1 - 1.8e-57 194.4 0.0 5.5e-30 104.3 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19731.1 - 3.3e-28 98.4 0.0 3.3e-12 46.0 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 EGO19731.1 - 5.1e-23 81.5 0.0 5.1e-23 81.5 0.0 2.7 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.17 EGO19731.1 - 2.7e-07 30.4 0.1 2.7e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 RWD domain APH PF01636.18 EGO19731.1 - 0.0012 18.6 0.8 0.0086 15.8 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGO19733.1 - 1.7e-08 33.9 0.0 2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO19733.1 - 5.5e-06 26.2 0.1 7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO19733.1 - 0.00068 18.7 0.0 0.00077 18.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO19733.1 - 0.0057 16.0 0.0 0.0074 15.6 0.0 1.3 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.6 EGO19733.1 - 0.0057 15.8 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 EGO19733.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EGO19733.1 - 0.05 12.6 0.0 0.11 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Hydrophobin PF01185.13 EGO19734.1 - 1.2e-24 86.5 10.8 1.5e-24 86.2 7.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF1427 PF07235.6 EGO19734.1 - 0.0031 17.5 0.5 0.5 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1427) Gly-zipper_YMGG PF13441.1 EGO19734.1 - 0.13 11.7 2.0 0.25 10.8 1.4 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Ribosomal_S5 PF00333.15 EGO19734.1 - 1 9.1 3.7 1.4 8.6 2.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S5, N-terminal domain ORC5_C PF14630.1 EGO19735.1 - 1.3e-46 159.3 0.0 1.6e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus YycC PF14174.1 EGO19735.1 - 0.012 15.2 0.0 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 YycC-like protein Ribosomal_L7Ae PF01248.21 EGO19736.1 - 2.9e-22 77.9 1.0 4.9e-22 77.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF879 PF05947.7 EGO19736.1 - 0.061 11.6 0.0 0.09 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) RNA_pol_Rpb1_1 PF04997.7 EGO19737.1 - 2.6e-117 391.8 0.0 3.6e-117 391.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGO19737.1 - 1.1e-104 349.6 0.0 1.5e-104 349.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 EGO19737.1 - 2e-69 233.0 0.0 3.7e-69 232.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 EGO19737.1 - 1.8e-68 229.6 0.0 3.6e-68 228.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGO19737.1 - 3.7e-50 169.7 0.0 1e-49 168.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EGO19737.1 - 6.5e-44 148.9 0.0 1.3e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EGO19737.1 - 3e-36 123.4 0.0 5.7e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EGO19737.1 - 7.3e-05 22.5 193.9 0.07 13.2 3.2 14.1 6 2 8 15 15 15 11 RNA polymerase Rpb1 C-terminal repeat Retrotrans_gag PF03732.12 EGO19738.1 - 1.1e-07 31.8 0.1 1.1e-07 31.8 0.1 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein rve PF00665.21 EGO19739.1 - 0.00013 22.0 0.1 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO19739.1 - 0.0023 17.8 0.1 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 CDC45 PF02724.9 EGO19741.1 - 0.14 10.1 14.5 0.2 9.6 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EGO19741.1 - 0.82 8.6 16.7 1.6 7.7 11.6 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO19741.1 - 1.7 6.5 17.7 0.87 7.4 10.3 1.7 2 0 0 2 2 2 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EGO19741.1 - 2.5 7.7 22.3 5.6 6.6 15.5 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.8 EGO19741.1 - 4.8 6.7 23.0 0.4 10.2 12.9 1.4 2 0 0 2 2 2 0 YL1 nuclear protein Myb_DNA-bind_3 PF12776.2 EGO19743.1 - 0.0035 17.9 0.1 0.38 11.4 0.0 2.6 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain DEAD PF00270.24 EGO19746.1 - 0.059 12.8 0.1 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Pkinase PF00069.20 EGO19747.1 - 1.6e-55 188.0 0.0 2.9e-55 187.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19747.1 - 1.4e-34 119.3 0.0 3.7e-34 117.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO19747.1 - 3.9e-07 29.3 0.0 6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO19747.1 - 0.027 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hid1 PF12722.2 EGO19751.1 - 9.8e-157 523.2 0.0 2.4e-156 521.9 0.0 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGO19751.1 - 2.1e-70 237.6 0.0 3.3e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein pKID PF02173.12 EGO19752.1 - 0.75 9.0 13.5 1.1 8.5 0.0 4.2 4 0 0 4 4 4 0 pKID domain Methyltransf_2 PF00891.13 EGO19753.1 - 2.3e-22 79.3 0.1 5.2e-21 74.9 0.0 2.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGO19753.1 - 4.9e-05 23.1 0.0 9.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO19753.1 - 0.0065 16.0 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rrf2 PF02082.15 EGO19753.1 - 0.0084 16.2 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator Methyltransf_18 PF12847.2 EGO19753.1 - 0.0092 16.5 0.4 0.079 13.5 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO19753.1 - 0.14 12.6 0.0 2.6 8.5 0.1 2.7 2 1 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 EGO19753.1 - 0.16 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SNAPc19 PF15497.1 EGO19754.1 - 0.067 13.3 0.7 0.071 13.3 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4381 PF14316.1 EGO19755.1 - 0.046 13.8 0.2 0.046 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) UCH PF00443.24 EGO19756.1 - 5e-44 150.4 0.0 9.2e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGO19756.1 - 2.9e-24 84.2 0.1 3e-13 49.1 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EGO19756.1 - 5.4e-24 84.0 12.3 1.5e-19 69.8 1.2 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGO19756.1 - 6.7e-16 58.5 0.0 3e-14 53.1 0.0 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Eapp_C PF10238.4 EGO19756.1 - 0.33 10.8 3.2 0.94 9.3 2.2 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein HSP70 PF00012.15 EGO19757.1 - 6.1e-59 199.4 4.6 2.4e-45 154.5 0.0 2.6 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EGO19757.1 - 5.2e-11 41.7 0.0 3.8e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein dCMP_cyt_deam_1 PF00383.17 EGO19758.1 - 2e-17 62.6 0.0 4e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGO19758.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain MafB19-deam PF14437.1 EGO19758.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase Bd3614-deam PF14439.1 EGO19758.1 - 0.2 11.4 0.9 0.42 10.4 0.5 1.6 1 1 1 2 2 2 0 Bd3614-like deaminase DUF904 PF06005.7 EGO19759.1 - 0.041 14.1 2.9 0.059 13.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HlyD PF00529.15 EGO19759.1 - 0.047 13.0 2.8 0.047 13.0 2.0 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Mnd1 PF03962.10 EGO19759.1 - 0.14 11.7 2.3 0.16 11.6 1.6 1.1 1 0 0 1 1 1 0 Mnd1 family HALZ PF02183.13 EGO19759.1 - 0.64 9.7 4.4 0.29 10.8 1.3 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Myc-LZ PF02344.10 EGO19759.1 - 0.86 9.2 7.1 3.2 7.4 4.9 2.0 1 1 0 1 1 1 0 Myc leucine zipper domain Oxysterol_BP PF01237.13 EGO19761.1 - 4.8e-115 383.8 0.0 7.5e-115 383.1 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 EGO19761.1 - 1.9e-16 59.7 1.3 1.4e-07 31.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGO19761.1 - 1.1e-15 56.5 0.9 0.0001 21.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGO19761.1 - 4.6e-14 52.5 0.0 4.9e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO19761.1 - 5.6e-12 44.6 0.3 0.0027 17.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGO19761.1 - 3.3e-09 37.0 0.2 1.6e-05 25.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 EGO19761.1 - 5.6e-08 32.9 0.0 1.5e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGO19761.1 - 9.1e-07 28.8 0.4 4e-06 26.8 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EGO19761.1 - 6e-05 23.2 0.3 0.00015 21.9 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain AA_permease PF00324.16 EGO19762.1 - 2.2e-116 389.0 36.3 2.4e-116 388.8 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO19762.1 - 1.2e-30 106.4 40.7 1.4e-30 106.1 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease Mem_trans PF03547.13 EGO19763.1 - 2.5e-23 82.0 2.3 3.2e-23 81.6 1.6 1.1 1 0 0 1 1 1 1 Membrane transport protein Grp1_Fun34_YaaH PF01184.14 EGO19764.1 - 1.2e-70 237.1 16.1 1.6e-70 236.7 11.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family NAP PF00956.13 EGO19765.1 - 1.1e-11 44.3 2.0 1.1e-11 44.3 1.4 1.3 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Snapin_Pallidin PF14712.1 EGO19765.1 - 0.042 14.1 0.3 0.074 13.3 0.2 1.4 1 0 0 1 1 1 0 Snapin/Pallidin TauD PF02668.11 EGO19766.1 - 1.2e-55 189.0 0.9 1.4e-55 188.7 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-4CXXC_R1 PF10497.4 EGO19767.1 - 0.00024 21.1 3.5 0.0003 20.8 2.4 1.1 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.1 EGO19767.1 - 0.13 11.9 4.5 2.3 7.9 0.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO19767.1 - 0.49 10.3 4.3 0.55 10.1 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGO19767.1 - 0.67 10.0 9.5 46 4.1 6.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGO19767.1 - 0.82 9.6 11.2 2.3 8.1 7.8 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.20 EGO19767.1 - 2.8 7.6 8.6 3.1 7.5 1.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EGO19767.1 - 5.4 6.3 7.1 10 5.5 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_2 PF13639.1 EGO19767.1 - 8.1 6.3 9.5 1.4e+02 2.4 6.6 2.1 1 1 0 1 1 1 0 Ring finger domain DZR PF12773.2 EGO19767.1 - 9.2 6.1 10.3 1.1e+02 2.6 7.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon HAD_2 PF13419.1 EGO19769.1 - 2.3e-23 83.3 0.0 3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO19769.1 - 7.5e-05 23.2 0.0 0.00032 21.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO19769.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_61 PF03443.9 EGO19770.1 - 5e-48 163.7 0.1 6.6e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EGO19771.1 - 5.7e-52 176.6 0.1 6.8e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_31 PF01055.21 EGO19773.1 - 1.7e-156 521.5 6.1 2e-156 521.2 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO19773.1 - 0.02 14.7 0.6 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 Galactose mutarotase-like UBN2_2 PF14227.1 EGO19774.1 - 3.5e-07 29.7 0.0 5.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO19774.1 - 0.0064 16.2 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_hydro_31 PF01055.21 EGO19776.1 - 1.1e-158 528.6 2.7 1.4e-158 528.3 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO19776.1 - 0.00094 18.9 0.3 0.0052 16.6 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like PNP_UDP_1 PF01048.15 EGO19777.1 - 3.1e-19 68.8 0.0 4.3e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HMG_box PF00505.14 EGO19778.1 - 1.3e-15 57.3 0.8 1.3e-15 57.3 0.6 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO19778.1 - 1.6e-12 47.6 0.3 2.9e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain Fasciclin PF02469.17 EGO19780.1 - 9e-32 109.7 1.6 1.8e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Pr_beta_C PF12465.3 EGO19780.1 - 0.084 12.1 0.2 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Pkinase PF00069.20 EGO19781.1 - 2.6e-71 239.8 0.0 3.3e-68 229.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19781.1 - 1.7e-35 122.3 0.0 9.1e-32 110.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO19781.1 - 1.6e-06 27.2 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGO19781.1 - 0.0007 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EGO19781.1 - 0.0029 16.7 0.1 0.0071 15.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO19781.1 - 0.041 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyridox_oxidase PF01243.15 EGO19782.1 - 0.0013 18.6 0.0 0.0039 17.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_90 PF05686.7 EGO19784.1 - 3.9e-37 127.8 0.0 9.8e-19 67.2 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 90 HTH_Tnp_1 PF01527.15 EGO19784.1 - 0.015 15.2 0.0 1.5 8.8 0.0 3.0 2 0 0 2 2 2 0 Transposase MgtE_N PF03448.12 EGO19784.1 - 0.19 12.0 0.0 15 5.9 0.0 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain E2R135 PF11570.3 EGO19784.1 - 0.27 11.3 1.4 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 YfzA PF14118.1 EGO19784.1 - 0.45 10.6 1.0 16 5.6 0.1 3.0 3 0 0 3 3 3 0 YfzA-like protein Asp_protease_2 PF13650.1 EGO19786.1 - 1.6e-05 25.3 0.0 2.2e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO19786.1 - 1.8e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO19786.1 - 0.0066 16.3 0.0 0.0084 16.0 0.0 1.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EGO19787.1 - 8.6e-09 35.3 0.6 3.8e-08 33.2 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO19787.1 - 8.9e-07 28.5 1.9 1.7e-06 27.6 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO19787.1 - 0.12 12.1 4.6 0.32 10.7 3.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO19787.1 - 0.44 10.2 3.3 0.89 9.2 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.1 EGO19788.1 - 0.11 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Pkinase PF00069.20 EGO19790.1 - 2.9e-10 39.7 0.0 7.3e-08 31.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19790.1 - 0.009 15.1 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_transf_90 PF05686.7 EGO19794.1 - 1.6e-12 46.8 0.2 2.8e-11 42.7 0.0 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 90 FTZ PF03867.9 EGO19795.1 - 0.55 9.4 3.4 1.5 7.9 2.3 1.7 1 1 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region VHP PF02209.14 EGO19795.1 - 0.64 9.7 10.6 13 5.6 0.0 4.1 1 1 3 4 4 4 0 Villin headpiece domain EBP PF05241.7 EGO19798.1 - 7.2e-09 34.9 7.0 9.9e-09 34.4 4.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein Bestrophin PF01062.16 EGO19799.1 - 4.9e-32 111.0 9.8 4.7e-18 65.1 1.8 3.1 3 0 0 3 3 3 3 Bestrophin, RFP-TM, chloride channel tRNA-synt_2b PF00587.20 EGO19800.1 - 4.7e-67 224.8 0.0 9.2e-67 223.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO19800.1 - 1.4e-21 76.1 0.0 3.4e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain p450 PF00067.17 EGO19803.1 - 2.4e-52 178.0 0.0 3e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APG12 PF04110.8 EGO19807.1 - 3.2e-30 104.1 0.0 3.9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGO19807.1 - 0.0082 16.1 0.0 0.0099 15.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.6 EGO19807.1 - 0.09 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain FAD-oxidase_C PF02913.14 EGO19810.1 - 2.9e-48 164.3 0.0 3.5e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO19810.1 - 1.7e-34 118.2 0.3 2.7e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.6 EGO19810.1 - 0.057 12.7 0.0 0.79 9.0 0.0 2.1 2 0 0 2 2 2 0 D-lactate dehydrogenase, membrane binding VHS PF00790.14 EGO19811.1 - 2.4e-35 121.2 0.0 8.5e-35 119.4 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EGO19811.1 - 9.2e-17 60.8 0.1 2.8e-16 59.3 0.1 1.8 2 0 0 2 2 2 1 GAT domain ACOX PF01756.14 EGO19811.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA oxidase zf-C2H2 PF00096.21 EGO19812.1 - 6.8e-06 26.1 7.7 0.00084 19.5 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO19812.1 - 2.9e-05 24.0 4.9 0.28 11.5 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO19812.1 - 0.00025 21.1 2.0 0.00025 21.1 1.4 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 EGO19812.1 - 0.00098 19.2 3.8 1.3 9.4 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain DUF3505 PF12013.3 EGO19812.1 - 0.43 10.8 4.8 3.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-TRAF PF02176.13 EGO19812.1 - 3.5 8.0 7.4 2.7 8.4 1.1 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger 4HBT PF03061.17 EGO19814.1 - 2.5e-08 33.9 0.0 4.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGO19814.1 - 0.036 13.8 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily zf-RING_2 PF13639.1 EGO19816.1 - 4.8e-13 48.7 6.6 7.5e-13 48.0 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO19816.1 - 4.4e-08 32.6 2.5 7e-08 32.0 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO19816.1 - 8.4e-08 32.2 3.1 1.6e-07 31.2 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO19816.1 - 2.1e-07 30.5 2.4 3.2e-07 29.9 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO19816.1 - 4.8e-07 29.6 5.5 7.9e-07 29.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO19816.1 - 2.1e-06 27.2 4.6 3.3e-06 26.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO19816.1 - 0.0043 16.8 5.1 0.017 14.9 3.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGO19816.1 - 0.014 14.9 2.6 0.032 13.8 1.7 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGO19816.1 - 0.017 14.8 1.9 0.034 13.8 0.2 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.9 EGO19816.1 - 0.033 13.6 6.2 0.025 14.0 1.7 2.1 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.2 EGO19816.1 - 0.045 13.7 10.1 0.06 13.3 5.7 2.0 1 1 1 2 2 2 0 RING-variant domain Rad50_zn_hook PF04423.9 EGO19816.1 - 0.22 10.9 0.9 7.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EGO19816.1 - 0.43 10.1 5.8 0.085 12.4 0.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EGO19816.1 - 0.57 10.1 5.8 0.98 9.3 4.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EGO19816.1 - 0.57 9.9 3.6 7.8 6.3 0.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EGO19816.1 - 1.1 9.0 5.0 1.2 8.8 2.5 1.8 1 1 1 2 2 2 0 PHD-finger FANCL_C PF11793.3 EGO19816.1 - 1.2 9.1 7.4 11 6.1 5.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain CK2S PF15011.1 EGO19817.1 - 0.057 13.2 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate UQ_con PF00179.21 EGO19818.1 - 2.4e-47 159.8 0.0 2.8e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO19818.1 - 7e-05 22.5 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGO19818.1 - 0.0077 15.9 0.1 0.015 14.9 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EGO19818.1 - 0.053 13.4 0.2 0.072 12.9 0.1 1.4 1 1 0 1 1 1 0 RWD domain Skp1_POZ PF03931.10 EGO19819.1 - 3.5e-07 30.2 0.0 1.4e-06 28.3 0.0 1.9 1 1 1 2 2 2 1 Skp1 family, tetramerisation domain Metallophos PF00149.23 EGO19820.1 - 9.1e-41 139.4 0.2 1.3e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF619 PF04768.8 EGO19821.1 - 5.2e-43 146.3 0.0 7.9e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EGO19821.1 - 1.5e-24 86.6 0.0 8.5e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGO19821.1 - 2e-19 70.1 0.0 3.9e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 EGO19821.1 - 0.00049 19.9 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain HDA2-3 PF11496.3 EGO19821.1 - 0.16 10.7 0.0 0.33 9.7 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 WD-3 PF09765.4 EGO19822.1 - 0.02 14.2 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 WD-repeat region Herpes_U5 PF05999.6 EGO19822.1 - 0.037 12.6 0.0 0.04 12.5 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus U5-like family CLASP_N PF12348.3 EGO19825.1 - 0.014 14.7 2.2 0.021 14.1 1.5 1.3 1 0 0 1 1 1 0 CLASP N terminal Baculo_PEP_C PF04513.7 EGO19825.1 - 0.024 14.4 11.0 0.15 11.9 1.2 2.8 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_5 PF12695.2 EGO19826.1 - 2.4e-22 79.2 0.0 3.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO19826.1 - 5.1e-17 62.5 0.2 3e-15 56.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO19826.1 - 6.8e-10 38.8 0.0 9.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EGO19826.1 - 6.2e-09 35.8 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EGO19826.1 - 2.9e-06 26.8 0.0 0.011 15.1 0.0 3.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EGO19826.1 - 6.8e-05 21.5 0.1 0.011 14.2 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 EGO19826.1 - 0.00014 21.2 0.0 0.071 12.3 0.0 2.6 3 0 0 3 3 3 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EGO19826.1 - 0.00095 18.7 0.1 0.0017 17.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO19826.1 - 0.006 16.0 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EGO19826.1 - 0.0065 15.9 0.1 0.01 15.2 0.1 1.4 1 1 0 1 1 1 1 Putative esterase DUF1057 PF06342.7 EGO19826.1 - 0.0077 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF818 PF05677.7 EGO19826.1 - 0.0085 14.8 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 EGO19826.1 - 0.01 15.0 0.0 0.079 12.1 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2305 PF10230.4 EGO19826.1 - 0.012 14.9 0.0 0.084 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 EGO19826.1 - 0.015 14.7 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.8 EGO19826.1 - 0.12 11.9 0.1 0.32 10.5 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein HORMA PF02301.13 EGO19827.1 - 2.7e-32 111.9 0.2 3.1e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EGO19827.1 - 0.0045 16.4 0.1 0.031 13.7 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 13 TisB_toxin PF13939.1 EGO19828.1 - 0.62 9.8 6.0 0.46 10.2 0.5 2.9 1 1 1 2 2 2 0 Toxin TisB, type I toxin-antitoxin system Peptidase_M1 PF01433.15 EGO19829.1 - 6.4e-56 190.1 0.0 9.9e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EGO19829.1 - 2.7e-28 98.3 0.1 5.5e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EGO19829.1 - 3.3e-11 43.3 0.0 6.9e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Myosin_head PF00063.16 EGO19830.1 - 1.2e-38 132.6 0.0 1.4e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) zf-C2H2_4 PF13894.1 EGO19832.1 - 3.2e-06 27.0 3.0 0.0017 18.5 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Lar_restr_allev PF14354.1 EGO19832.1 - 0.0015 18.7 1.0 0.6 10.4 0.1 2.5 1 1 1 2 2 2 2 Restriction alleviation protein Lar zf-C2H2 PF00096.21 EGO19832.1 - 0.021 15.1 0.3 0.021 15.1 0.2 3.2 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EGO19832.1 - 0.092 13.0 0.6 0.52 10.6 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 EGO19832.1 - 0.2 11.9 3.2 0.54 10.5 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HypA PF01155.14 EGO19832.1 - 0.29 10.8 2.8 0.43 10.2 0.5 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C2H2_jaz PF12171.3 EGO19832.1 - 4.2 7.6 8.1 4.4 7.5 0.0 3.1 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGO19833.1 - 3.2e-05 23.9 5.0 0.012 15.8 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO19833.1 - 0.00052 20.1 10.1 0.0013 18.9 0.1 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-BED PF02892.10 EGO19833.1 - 0.0014 18.3 2.8 0.1 12.3 0.8 2.5 2 0 0 2 2 2 2 BED zinc finger zf-met PF12874.2 EGO19833.1 - 0.015 15.4 0.5 15 5.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ebola_NP PF05505.7 EGO19833.1 - 4.1 5.3 8.5 6.4 4.7 5.9 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein RRM_1 PF00076.17 EGO19834.1 - 1.3e-18 66.4 0.0 2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO19834.1 - 2.9e-14 52.8 0.0 4.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO19834.1 - 1.2e-10 41.0 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Catalase PF00199.14 EGO19835.1 - 2.5e-179 595.8 1.2 3.2e-179 595.5 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGO19835.1 - 1.3e-17 63.3 0.6 2.8e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Rhodanese PF00581.15 EGO19836.1 - 4.9e-18 65.5 0.0 8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Ctr PF04145.10 EGO19837.1 - 1.7e-22 80.0 0.3 2.2e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.10 EGO19838.1 - 5.3e-22 78.4 0.2 6.7e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3959 PF13105.1 EGO19838.1 - 0.15 11.3 0.5 0.23 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) rRNA_proc-arch PF13234.1 EGO19839.1 - 6.3e-95 317.3 0.0 9.4e-95 316.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EGO19839.1 - 7.9e-57 191.3 0.4 1.6e-56 190.3 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGO19839.1 - 2.6e-21 75.8 0.0 8.4e-21 74.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO19839.1 - 3e-07 30.2 0.0 7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EGO19839.1 - 0.0066 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EGO19839.1 - 0.025 14.3 0.0 0.32 10.8 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO19839.1 - 0.089 12.5 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain vATP-synt_E PF01991.13 EGO19840.1 - 5.6e-53 179.1 9.5 6.4e-53 178.9 6.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RsmJ PF04378.8 EGO19840.1 - 0.08 11.9 0.3 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ DUF883 PF05957.8 EGO19840.1 - 3.1 8.2 6.7 0.95 9.9 1.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WD40 PF00400.27 EGO19841.1 - 5.6e-110 355.7 62.5 2.1e-12 46.4 0.5 14.3 13 2 0 13 13 13 12 WD domain, G-beta repeat PD40 PF07676.7 EGO19841.1 - 1.5e-10 40.4 19.3 2.8 7.6 0.0 10.5 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EGO19841.1 - 1.1e-09 38.2 0.0 0.025 14.3 0.0 4.6 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A C2 PF00168.25 EGO19841.1 - 4.4e-08 32.8 0.0 1.4e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF3312 PF11768.3 EGO19841.1 - 0.00014 20.2 0.0 0.97 7.5 0.0 4.3 3 1 2 5 5 5 2 Protein of unknown function (DUF3312) Gmad1 PF10647.4 EGO19841.1 - 0.00015 21.2 3.3 0.021 14.1 0.0 4.7 1 1 2 4 4 4 2 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 EGO19841.1 - 0.00094 18.8 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EGO19841.1 - 0.0017 17.2 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EGO19841.1 - 0.002 18.1 2.6 0.028 14.3 0.5 3.0 2 1 0 2 2 2 1 AAA ATPase domain Strep_his_triad PF04270.8 EGO19841.1 - 0.009 15.7 0.1 0.59 9.9 0.0 3.4 3 0 0 3 3 3 1 Streptococcal histidine triad protein DPPIV_N PF00930.16 EGO19841.1 - 0.0092 14.6 0.1 11 4.4 0.0 4.7 3 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_3 PF13570.1 EGO19841.1 - 0.015 15.5 10.8 22 5.4 0.2 7.1 6 1 2 8 8 8 0 PQQ-like domain AAA PF00004.24 EGO19841.1 - 0.023 14.9 0.0 0.1 12.7 0.0 2.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGO19841.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO19841.1 - 0.096 12.8 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cuticle_3 PF11018.3 EGO19841.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Pupal cuticle protein C1 APS_kinase PF01583.15 EGO19841.1 - 0.23 11.1 0.0 0.47 10.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Peptidase_S9_N PF02897.10 EGO19841.1 - 0.41 9.1 1.2 42 2.5 0.0 4.2 4 1 0 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Glyco_hyd_65N_2 PF14498.1 EGO19842.1 - 1.6e-46 158.8 0.1 2.4e-46 158.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Mss4 PF04421.8 EGO19843.1 - 1.8e-08 34.0 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Mss4 protein DUF4381 PF14316.1 EGO19846.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Globin PF00042.17 EGO19849.1 - 0.021 15.1 1.2 0.029 14.6 0.2 1.6 2 0 0 2 2 2 0 Globin PEARLI-4 PF05278.7 EGO19850.1 - 0.019 14.3 0.1 0.019 14.3 0.0 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Sugarporin_N PF11471.3 EGO19850.1 - 0.83 9.3 6.6 3.6 7.3 4.6 2.1 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension COG2 PF06148.6 EGO19850.1 - 1.7 8.5 6.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EGO19850.1 - 7.9 6.0 8.1 9.7 5.7 0.8 2.5 3 0 0 3 3 3 0 IncA protein Acetyltransf_7 PF13508.1 EGO19851.1 - 2.4e-05 24.4 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO19851.1 - 6.2e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family GMC_oxred_N PF00732.14 EGO19852.1 - 5.8e-21 74.9 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO19852.1 - 6.4e-18 65.4 0.0 4.5e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EGO19852.1 - 6.2e-10 38.5 0.1 2.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO19852.1 - 7.2e-07 28.3 0.3 3.5e-05 22.8 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EGO19852.1 - 3.4e-06 26.4 0.0 3.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO19852.1 - 2.8e-05 23.3 0.1 0.002 17.2 0.1 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EGO19852.1 - 3.1e-05 23.9 0.2 0.00014 21.8 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO19852.1 - 0.0001 20.9 0.1 0.00019 20.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGO19852.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO19852.1 - 0.0005 19.2 0.3 0.00097 18.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGO19852.1 - 0.0019 18.3 0.1 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO19852.1 - 0.066 12.0 0.2 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Ras PF00071.17 EGO19853.1 - 2.5e-34 118.0 0.3 3e-34 117.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO19853.1 - 2.4e-23 82.9 0.1 8.7e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGO19853.1 - 6.4e-08 32.0 0.1 7.9e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO19853.1 - 7.9e-08 31.7 0.2 1e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO19853.1 - 0.0094 15.8 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGO19853.1 - 0.011 14.4 0.4 0.031 12.9 0.0 1.8 1 1 2 3 3 3 0 G-protein alpha subunit DLIC PF05783.6 EGO19853.1 - 0.043 12.4 0.0 4.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.4 EGO19853.1 - 0.14 11.6 0.3 0.58 9.6 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_18 PF00704.23 EGO19854.1 - 9.4e-92 308.0 10.3 9.4e-92 308.0 7.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 EGO19854.1 - 9.2e-12 44.3 15.1 3.2e-11 42.6 10.5 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain DUF4569 PF15133.1 EGO19854.1 - 0.56 9.5 3.4 5.7 6.2 1.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4569) Pkinase PF00069.20 EGO19855.1 - 2.2e-71 240.0 0.0 2.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19855.1 - 1.8e-34 119.0 0.0 2.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGO19855.1 - 1.3e-10 41.5 2.6 3e-10 40.4 1.8 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO19855.1 - 0.0013 17.7 0.0 0.0028 16.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO19855.1 - 0.025 14.3 0.1 0.062 13.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO19855.1 - 0.081 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP_assoc PF03828.14 EGO19857.1 - 4e-06 26.6 0.0 0.00063 19.6 0.0 2.6 2 0 0 2 2 2 2 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.6 EGO19857.1 - 0.029 14.2 0.6 0.052 13.4 0.0 1.6 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Paf67 PF10255.4 EGO19859.1 - 3.5e-145 483.9 0.0 4.7e-145 483.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Apc3 PF12895.2 EGO19859.1 - 0.04 14.0 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGO19859.1 - 0.058 13.3 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fucose_iso_N2 PF07882.7 EGO19860.1 - 0.043 13.4 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Mer2 PF09074.5 EGO19860.1 - 0.082 12.8 0.4 0.093 12.6 0.3 1.1 1 0 0 1 1 1 0 Mer2 Tnp_P_element PF12017.3 EGO19860.1 - 0.32 10.1 1.4 0.44 9.7 1.0 1.1 1 0 0 1 1 1 0 Transposase protein SNARE PF05739.14 EGO19861.1 - 2.2e-13 49.7 0.8 2.2e-13 49.7 0.6 2.9 2 1 1 3 3 3 2 SNARE domain GATase PF00117.23 EGO19863.1 - 1.3e-10 41.0 0.0 4e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO19863.1 - 0.013 14.9 0.2 0.028 13.8 0.1 1.7 1 1 0 1 1 1 0 Peptidase C26 SNO PF01174.14 EGO19863.1 - 0.02 14.5 0.0 0.072 12.7 0.0 1.7 1 1 0 1 1 1 0 SNO glutamine amidotransferase family p450 PF00067.17 EGO19864.1 - 9.5e-62 209.0 0.0 1.2e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 EGO19867.1 - 3.9e-22 78.8 0.0 1.7e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO19867.1 - 1.7e-10 40.0 0.0 2.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO19867.1 - 2e-07 31.2 0.0 3.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO19867.1 - 8e-07 28.2 0.1 3.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EGO19867.1 - 8.3e-07 28.1 0.0 1.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EGO19867.1 - 1.5e-06 28.2 0.1 4.6e-06 26.6 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO19867.1 - 1.2e-05 24.3 0.0 0.0016 17.3 0.1 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EGO19867.1 - 0.0025 17.4 0.1 0.032 13.9 0.1 2.1 1 1 0 1 1 1 1 KR domain CUE PF02845.11 EGO19868.1 - 1.1e-11 43.9 0.1 2e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 CUE domain Spc97_Spc98 PF04130.8 EGO19871.1 - 5.7e-125 417.6 1.6 7e-125 417.4 1.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family S4 PF01479.20 EGO19872.1 - 8.2e-11 41.1 0.0 1.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EGO19872.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ferric_reduct PF01794.14 EGO19873.1 - 5.7e-16 58.7 5.1 1.2e-15 57.6 3.6 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO19873.1 - 2.2e-12 46.7 0.0 4.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGO19873.1 - 2.9e-11 43.5 0.0 1.2e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain PAXNEB PF05625.6 EGO19874.1 - 8.9e-45 153.0 0.0 2.3e-41 141.8 0.0 2.0 1 1 1 2 2 2 2 PAXNEB protein GST_N_3 PF13417.1 EGO19875.1 - 1.5e-15 57.1 0.2 4e-15 55.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19875.1 - 2.9e-09 36.8 0.0 5.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO19875.1 - 2.2e-06 27.4 0.0 7.2e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO19875.1 - 0.00031 21.1 0.1 0.00053 20.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO19875.1 - 0.00072 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO19875.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain STE3 PF02076.10 EGO19876.1 - 8e-61 205.6 17.4 1.1e-60 205.1 12.0 1.2 1 0 0 1 1 1 1 Pheromone A receptor GST_N_3 PF13417.1 EGO19877.1 - 8.4e-17 61.1 0.1 2.2e-16 59.8 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO19877.1 - 1e-09 38.2 0.1 1.8e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO19877.1 - 0.00043 20.7 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO19877.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO19877.1 - 0.032 14.1 0.0 0.055 13.3 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.6 EGO19878.1 - 1.8e-22 79.9 0.0 4.2e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EGO19879.1 - 3.2e-37 128.0 30.9 1e-31 109.9 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EGO19880.1 - 6.8e-51 173.0 62.3 7.8e-36 123.4 24.6 4.0 1 1 3 4 4 4 4 Major Facilitator Superfamily Shisa PF13908.1 EGO19880.1 - 0.14 12.3 1.6 6 6.9 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 EGO19881.1 - 7.7e-31 107.0 32.0 3.9e-28 98.1 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_1 PF00190.17 EGO19882.1 - 1.4e-28 99.1 0.0 1.5e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGO19882.1 - 1.2e-22 79.2 3.6 1.4e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGO19882.1 - 2.1e-07 30.2 0.0 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EGO19882.1 - 0.00012 21.7 0.9 0.021 14.5 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EGO19882.1 - 0.0015 18.1 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Cupin ARD PF03079.9 EGO19882.1 - 0.061 13.2 0.1 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family FA_desaturase PF00487.19 EGO19883.1 - 4.6e-14 52.4 23.4 4.6e-14 52.4 16.2 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGO19883.1 - 8.7e-13 47.8 0.0 2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SGL PF08450.7 EGO19884.1 - 1.7e-23 83.2 0.0 3.3e-23 82.3 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EGO19884.1 - 1.1e-05 25.3 0.0 0.0001 22.2 0.0 2.4 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EGO19884.1 - 0.0025 17.7 0.0 0.028 14.4 0.0 2.6 2 0 0 2 2 2 1 Arylesterase DUF1049 PF06305.6 EGO19885.1 - 0.0048 16.3 0.2 0.049 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) NfeD PF01957.13 EGO19885.1 - 0.029 14.4 2.1 0.031 14.4 0.1 1.8 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EGO19885.1 - 0.28 10.5 6.2 0.088 12.2 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CopD PF05425.8 EGO19885.1 - 0.77 9.9 6.8 0.097 12.8 0.8 2.1 1 1 1 2 2 2 0 Copper resistance protein D PgaD PF13994.1 EGO19885.1 - 3 7.3 10.8 5 6.6 5.1 2.3 1 1 1 2 2 2 0 PgaD-like protein DUF983 PF06170.7 EGO19885.1 - 3.5 7.7 5.5 0.45 10.6 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) FA_desaturase PF00487.19 EGO19885.1 - 8.4 5.7 11.4 8.5 5.7 7.0 1.7 1 1 0 1 1 1 0 Fatty acid desaturase L51_S25_CI-B8 PF05047.11 EGO19886.1 - 2.3e-14 52.8 0.0 3.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.13 EGO19886.1 - 0.15 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase RGS PF00615.14 EGO19887.1 - 1.3e-08 34.9 1.9 0.00056 19.9 0.2 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain DUF4149 PF13664.1 EGO19887.1 - 0.59 10.2 4.1 0.25 11.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) AMP-binding PF00501.23 EGO19888.1 - 1.2e-66 224.8 0.0 1.5e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO19888.1 - 5.3e-17 62.5 0.1 1.2e-16 61.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EGO19889.1 - 2.9e-26 92.3 0.1 5.7e-26 91.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO19889.1 - 7.5e-14 52.0 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO19889.1 - 5.1e-11 42.5 0.0 8.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO19889.1 - 5e-07 29.8 0.1 1.3e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO19889.1 - 1.2e-06 28.1 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO19889.1 - 0.0076 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EGO19889.1 - 0.018 14.3 0.1 0.05 12.8 0.0 1.7 2 1 1 3 3 3 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EGO19889.1 - 0.033 13.9 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EGO19889.1 - 0.033 12.9 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HMG_box PF00505.14 EGO19890.1 - 1.8e-15 56.9 4.9 1.7e-08 34.6 0.1 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO19890.1 - 1.2e-10 41.5 0.9 1.8e-05 25.0 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain Peptidase_M61 PF05299.7 EGO19890.1 - 0.052 13.5 0.2 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 M61 glycyl aminopeptidase TATR PF03430.8 EGO19890.1 - 1.7 7.1 6.0 2.6 6.5 4.2 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF1423 PF07227.6 EGO19890.1 - 6.5 5.2 7.5 3.8 6.0 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) Med8 PF10232.4 EGO19891.1 - 0.00014 21.4 2.9 0.00051 19.6 2.0 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DASH_Duo1 PF08651.5 EGO19891.1 - 0.037 13.6 0.1 0.13 11.8 0.1 1.9 1 1 0 1 1 1 0 DASH complex subunit Duo1 QRPTase_C PF01729.14 EGO19891.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Rib_5-P_isom_A PF06026.9 EGO19894.1 - 2.8e-55 186.2 0.0 3.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EGO19894.1 - 0.094 12.3 0.0 1.9 8.0 0.0 2.2 1 1 0 1 1 1 0 DeoR C terminal sensor domain EPSP_synthase PF00275.15 EGO19895.1 - 9e-120 399.9 0.2 6.1e-119 397.1 0.0 2.0 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EGO19895.1 - 1.3e-98 329.0 0.2 2.9e-98 327.9 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EGO19895.1 - 9e-61 205.3 0.0 1.5e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EGO19895.1 - 2.7e-35 121.5 0.0 1.2e-33 116.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGO19895.1 - 6.7e-25 86.9 0.0 1.8e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGO19895.1 - 1.2e-10 41.5 0.0 3.6e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EGO19895.1 - 4.3e-08 32.7 0.2 1e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EGO19895.1 - 9.2e-05 23.2 0.0 0.00025 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO19895.1 - 0.005 16.7 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Pyr_redox_2 PF07992.9 EGO19896.1 - 1.1e-24 87.4 0.0 1.6e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO19896.1 - 3.6e-11 43.3 0.1 5.4e-10 39.5 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO19896.1 - 0.00044 20.3 0.0 0.24 11.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF793 PF05633.6 EGO19896.1 - 0.01 14.6 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Remorin_C PF03763.8 EGO19896.1 - 0.038 13.5 1.5 0.076 12.5 1.1 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region Form-deh_trans PF09163.6 EGO19896.1 - 0.09 12.2 0.2 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane HI0933_like PF03486.9 EGO19896.1 - 0.19 10.1 0.6 0.53 8.6 0.0 1.8 1 1 1 2 2 2 0 HI0933-like protein FlxA PF14282.1 EGO19896.1 - 0.2 11.6 0.4 0.38 10.7 0.3 1.4 1 0 0 1 1 1 0 FlxA-like protein Ferric_reduct PF01794.14 EGO19897.1 - 3.8e-16 59.3 5.6 3.8e-16 59.3 3.9 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO19897.1 - 7.6e-14 51.4 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGO19897.1 - 3.6e-08 33.4 0.0 2.4e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Cu-oxidase_4 PF02578.10 EGO19897.1 - 0.05 12.6 0.4 0.091 11.8 0.3 1.3 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Glyco_hydro_12 PF01670.11 EGO19898.1 - 1.4e-25 89.9 1.5 2.5e-25 89.0 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Hid1 PF12722.2 EGO19899.1 - 1.8 6.1 5.8 1.7 6.2 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V-ATPase_G PF03179.10 EGO19899.1 - 2.4 8.4 7.6 3.5 7.9 5.2 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Transferase PF02458.10 EGO19900.1 - 8.2e-28 97.0 0.0 1.2e-22 80.0 0.0 2.0 2 0 0 2 2 2 2 Transferase family MSA-2c PF12238.3 EGO19904.1 - 0.14 11.7 0.4 0.19 11.3 0.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Herpes_LMP1 PF05297.6 EGO19904.1 - 0.22 10.3 3.7 0.26 10.1 2.5 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1744 PF08490.7 EGO19905.1 - 1.1e-104 350.1 0.0 1.5e-104 349.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGO19905.1 - 4.6e-62 209.7 0.0 8.1e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGO19905.1 - 6e-20 71.4 0.0 9.7e-19 67.4 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGO19905.1 - 5.6e-07 29.3 0.5 3.8e-06 26.6 0.4 2.2 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGO19905.1 - 0.00033 20.4 0.0 0.0016 18.2 0.0 2.2 1 0 0 1 1 1 1 RNase_H superfamily MAP65_ASE1 PF03999.7 EGO19906.1 - 6.4e-58 196.8 9.8 3.4e-56 191.1 0.2 2.5 3 0 0 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Hydantoinase_B PF02538.9 EGO19908.1 - 5.1e-188 625.5 0.3 3.6e-187 622.7 0.2 1.8 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase zf-UBR PF02207.15 EGO19909.1 - 5e-11 42.1 10.5 5e-11 42.1 7.3 3.7 4 1 1 5 5 5 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EGO19909.1 - 1.3e-07 31.1 1.1 1.3e-07 31.1 0.7 4.1 4 1 1 5 5 5 1 PHD-finger RdRP_5 PF07925.6 EGO19910.1 - 0.034 11.5 0.1 0.037 11.4 0.1 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 H_lectin PF09458.5 EGO19910.1 - 0.043 13.4 0.4 0.083 12.5 0.1 1.5 2 0 0 2 2 2 0 H-type lectin domain DUF4532 PF15046.1 EGO19910.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) CGGC PF08821.6 EGO19911.1 - 0.02 14.9 0.7 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 CGGC domain DUF4027 PF13219.1 EGO19912.1 - 0.14 11.5 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Acyl-CoA_dh_1 PF00441.19 EGO19913.1 - 0.00023 21.3 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 EGO19914.1 - 2.8e-16 59.2 51.9 5.4e-14 51.6 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD-oxidase_C PF02913.14 EGO19916.1 - 3.2e-46 157.6 0.0 5.8e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO19916.1 - 2.5e-28 98.2 0.2 3.9e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain PLRV_ORF5 PF01690.12 EGO19916.1 - 0.061 12.4 0.2 0.094 11.8 0.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ZF-HD_dimer PF04770.7 EGO19918.1 - 0.45 10.6 2.1 0.91 9.6 1.4 1.5 1 0 0 1 1 1 0 ZF-HD protein dimerisation region FAD_binding_3 PF01494.14 EGO19919.1 - 1.4e-16 60.4 0.0 3.7e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO19919.1 - 8.9e-08 31.4 4.7 5.9e-05 22.1 0.3 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO19919.1 - 1e-06 28.6 0.2 2.7e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO19919.1 - 1.8e-05 23.7 0.0 5.5e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO19919.1 - 5.4e-05 23.1 0.1 0.0003 20.7 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO19919.1 - 0.00032 21.0 0.1 0.0076 16.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO19919.1 - 0.0004 19.4 0.3 0.68 8.7 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.19 EGO19919.1 - 0.00096 18.3 0.9 0.023 13.7 0.1 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EGO19919.1 - 0.0031 16.0 0.0 0.045 12.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGO19919.1 - 0.023 13.8 0.1 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EGO19919.1 - 0.077 11.6 0.0 7.5 5.0 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase HIG_1_N PF04588.8 EGO19920.1 - 0.00011 21.8 1.0 0.00021 20.9 0.7 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3859 PF12975.2 EGO19920.1 - 0.057 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) EF-hand_1 PF00036.27 EGO19923.1 - 5.9e-43 140.9 12.6 2.6e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO19923.1 - 1.5e-38 130.7 3.7 2.6e-21 75.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGO19923.1 - 1.4e-34 117.4 11.1 1.2e-16 60.0 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGO19923.1 - 1.1e-31 105.8 7.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGO19923.1 - 2.5e-28 96.1 7.3 8.3e-07 28.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGO19923.1 - 2.6e-15 56.0 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGO19923.1 - 2.4e-10 40.0 0.7 6.6e-05 22.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGO19923.1 - 3.9e-09 36.5 0.0 0.0004 20.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGO19923.1 - 2e-07 30.5 0.1 0.11 12.0 0.0 3.8 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGO19923.1 - 1.8e-06 27.7 1.4 2.5e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_like PF09279.6 EGO19923.1 - 0.00021 21.2 0.4 0.0036 17.2 0.0 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1103 PF06513.6 EGO19923.1 - 0.00027 20.4 1.2 0.00031 20.2 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 EGO19923.1 - 0.00029 20.4 0.1 0.037 13.6 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 EGO19923.1 - 0.0032 17.2 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.5 EGO19923.1 - 0.014 15.1 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 EGO19923.1 - 0.018 14.7 0.1 3.9 7.3 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 EGO19923.1 - 0.034 14.1 1.2 6.2 6.8 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EGO19923.1 - 0.042 13.4 0.1 0.81 9.2 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EGO19923.1 - 0.067 13.5 0.6 13 6.2 0.0 2.4 1 1 1 2 2 2 0 Toprim-like LNS2 PF08235.8 EGO19923.1 - 0.084 12.4 0.1 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Pkinase PF00069.20 EGO19924.1 - 2.4e-70 236.6 0.0 3.2e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19924.1 - 1.1e-39 136.0 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO19924.1 - 1.7e-09 37.0 0.0 3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO19924.1 - 0.0058 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Synaptobrevin PF00957.16 EGO19925.1 - 5.7e-34 115.5 3.1 6.5e-34 115.4 2.2 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 EGO19925.1 - 0.0047 15.5 0.9 0.0057 15.2 0.6 1.0 1 0 0 1 1 1 1 TMEM117 protein family DUF515 PF04415.7 EGO19925.1 - 0.017 13.3 0.2 0.019 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2976 PF11190.3 EGO19925.1 - 0.2 11.1 2.4 0.13 11.7 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Acetyltransf_7 PF13508.1 EGO19926.1 - 8.6e-11 41.8 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO19926.1 - 2.8e-10 40.0 0.0 4.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGO19926.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO19926.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Chitin_synth_2 PF03142.10 EGO19927.1 - 7.7e-70 235.7 2.0 2.5e-68 230.7 0.9 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO19927.1 - 0.00031 20.4 0.1 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Mo25 PF08569.6 EGO19930.1 - 2e-123 411.7 5.0 2.2e-123 411.5 3.5 1.0 1 0 0 1 1 1 1 Mo25-like F-box PF00646.28 EGO19931.1 - 6.7e-06 25.6 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO19931.1 - 0.002 17.8 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EGO19931.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain NfI_DNAbd_pre-N PF10524.4 EGO19931.1 - 0.099 12.2 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Pkinase PF00069.20 EGO19932.1 - 1.7e-07 30.6 0.0 1.9e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19932.1 - 0.0009 18.3 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.22 EGO19934.1 - 3.5e-55 183.6 0.8 7.7e-18 63.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp PF00026.18 EGO19935.1 - 3e-35 121.9 0.0 2e-17 63.4 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO19935.1 - 0.021 15.2 0.5 2.1 8.9 0.2 3.3 2 1 0 2 2 2 0 Aspartyl protease Jag_N PF14804.1 EGO19935.1 - 0.22 11.5 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 Jag N-terminus Fungal_trans PF04082.13 EGO19936.1 - 1.5e-24 86.3 0.0 3.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO19936.1 - 6.4e-10 38.7 11.0 1.3e-09 37.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_21 PF09976.4 EGO19936.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Isochorismatase PF00857.15 EGO19938.1 - 6.4e-16 58.7 0.0 6.4e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family F-box-like PF12937.2 EGO19940.1 - 1.6e-07 30.9 2.1 1.8e-07 30.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EGO19940.1 - 0.0022 17.5 2.4 0.19 11.3 0.0 4.0 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 EGO19940.1 - 0.091 13.2 0.9 29 5.3 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EGO19940.1 - 0.26 11.6 2.4 2.2e+02 2.8 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 EGO19940.1 - 0.4 10.4 5.4 0.8 9.5 0.0 3.9 5 0 0 5 5 5 0 Leucine rich repeat E1-E2_ATPase PF00122.15 EGO19941.1 - 4.9e-15 55.2 0.1 4.9e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGO19941.1 - 9.7e-13 49.0 0.5 3.4e-11 43.9 0.3 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO19941.1 - 2.3e-12 46.7 0.0 4.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO19941.1 - 4.1e-12 46.6 0.0 2.5e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO19941.1 - 0.002 17.7 0.1 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 EGO19942.1 - 5.7e-51 172.4 0.0 5.2e-29 101.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO19942.1 - 1e-46 159.5 11.5 1.1e-24 87.2 2.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGO19942.1 - 1.3e-09 37.5 5.0 0.0021 17.3 0.2 4.4 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGO19942.1 - 2.2e-08 33.7 0.5 0.0013 18.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGO19942.1 - 1e-07 31.3 3.2 0.00053 19.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EGO19942.1 - 4.1e-07 29.1 0.3 0.025 13.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EGO19942.1 - 1.8e-06 28.4 0.1 0.00035 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO19942.1 - 1.8e-06 28.0 3.0 0.025 14.5 0.6 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EGO19942.1 - 3.1e-06 27.3 1.8 1.1 9.1 0.0 4.4 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 EGO19942.1 - 2.3e-05 24.3 2.1 0.0056 16.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EGO19942.1 - 3.1e-05 23.5 1.5 0.066 12.6 0.0 2.7 2 1 1 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 EGO19942.1 - 7.2e-05 22.7 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGO19942.1 - 8.6e-05 22.0 0.1 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 EGO19942.1 - 9.9e-05 22.8 0.1 0.19 12.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EGO19942.1 - 0.00012 22.2 0.8 0.42 10.7 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGO19942.1 - 0.00048 20.4 0.5 0.69 10.2 0.1 3.1 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EGO19942.1 - 0.00062 18.9 0.1 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EGO19942.1 - 0.00096 18.8 0.3 0.13 11.9 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGO19942.1 - 0.0012 19.6 0.1 0.53 11.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGO19942.1 - 0.0015 17.6 0.1 0.41 9.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.4 EGO19942.1 - 0.0036 16.3 2.3 0.49 9.3 0.0 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EGO19942.1 - 0.0086 15.7 1.6 1.6 8.3 0.1 2.6 2 0 0 2 2 2 1 NACHT domain Herpes_Helicase PF02689.9 EGO19942.1 - 0.034 11.8 0.0 0.11 10.1 0.0 1.7 2 0 0 2 2 2 0 Helicase Dynamin_N PF00350.18 EGO19942.1 - 0.039 13.7 2.3 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 EGO19942.1 - 0.041 13.4 0.1 3.2 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EGO19942.1 - 0.041 12.5 2.3 1 7.8 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 EGO19942.1 - 0.054 13.4 0.4 7.6 6.5 0.1 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.12 EGO19942.1 - 0.086 12.2 0.1 13 5.1 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.14 EGO19942.1 - 0.088 12.2 0.9 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EGO19942.1 - 0.11 12.7 0.0 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EGO19942.1 - 0.12 12.1 1.8 5.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_33 PF13671.1 EGO19942.1 - 0.14 12.0 0.2 5.7 6.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGO19942.1 - 0.15 11.7 1.4 5.8 6.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EGO19942.1 - 0.23 10.5 0.5 4.7 6.2 0.1 2.5 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 EGO19942.1 - 0.26 10.1 0.4 9 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Pox_A32 PF04665.7 EGO19942.1 - 0.42 9.8 0.7 13 5.0 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Zot PF05707.7 EGO19942.1 - 0.52 9.7 0.9 7.2 6.0 0.0 2.5 3 0 0 3 3 2 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.10 EGO19942.1 - 0.59 9.8 2.7 8.2 6.1 0.0 2.8 3 0 0 3 3 3 0 NTPase DAP3 PF10236.4 EGO19942.1 - 0.61 8.9 0.9 12 4.7 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NAD_binding_4 PF07993.7 EGO19943.1 - 4e-32 111.1 0.0 5.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO19943.1 - 2.6e-22 78.8 0.0 8.3e-15 54.0 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme NAD_binding_10 PF13460.1 EGO19943.1 - 2.4e-07 30.9 0.0 1.3e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO19943.1 - 5e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO19943.1 - 0.0012 18.7 0.7 0.0055 16.6 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EGO19943.1 - 0.0063 16.7 0.1 0.029 14.6 0.1 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EGO19943.1 - 0.11 11.1 0.0 0.75 8.4 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CCHC_3 PF13917.1 EGO19944.1 - 1.3e-06 28.0 1.7 1.4e-06 27.9 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO19944.1 - 1.8e-05 24.4 5.2 2.4e-05 24.0 3.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO19944.1 - 0.22 11.0 3.1 0.32 10.4 2.2 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SNARE PF05739.14 EGO19946.1 - 3.9e-05 23.2 0.0 5.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Methyltransf_25 PF13649.1 EGO19947.1 - 1.3e-07 31.8 0.1 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO19947.1 - 8.1e-06 25.5 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO19947.1 - 0.0017 18.8 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO19947.1 - 0.087 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGO19947.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Aldedh PF00171.17 EGO19950.1 - 1.3e-83 280.9 0.0 1.7e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO19950.1 - 1.8e-05 23.6 0.0 2.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF4135 PF13575.1 EGO19950.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) adh_short PF00106.20 EGO19951.1 - 2.9e-28 98.8 4.8 3.6e-28 98.5 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO19951.1 - 6.3e-18 65.4 0.6 7.8e-18 65.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO19951.1 - 7.5e-13 48.5 2.8 1.1e-12 48.0 1.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO19951.1 - 0.013 14.8 0.3 0.018 14.4 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Succ_DH_flav_C PF02910.15 EGO19951.1 - 0.11 12.3 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term Pyr_redox_dim PF02852.17 EGO19954.1 - 1.8e-42 143.8 2.6 1.1e-41 141.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EGO19954.1 - 6.5e-38 130.6 14.5 2.6e-37 128.6 10.1 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO19954.1 - 1.6e-22 79.6 8.7 1.1e-19 70.5 1.9 3.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO19954.1 - 1.7e-12 47.8 0.6 5.5e-07 29.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO19954.1 - 3e-10 39.5 9.3 3.1e-10 39.4 0.5 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGO19954.1 - 5.5e-10 38.9 0.2 5.5e-10 38.9 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO19954.1 - 7e-09 35.5 3.8 7.8e-05 22.6 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO19954.1 - 2.9e-08 33.0 13.3 0.0054 15.6 0.1 4.3 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO19954.1 - 1.2e-06 27.6 3.1 1.2e-06 27.6 2.2 3.4 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.9 EGO19954.1 - 4.9e-06 25.2 15.9 0.00031 19.3 0.8 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 EGO19954.1 - 1.7e-05 24.0 5.7 0.00036 19.6 0.1 2.5 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 EGO19954.1 - 1.8e-05 23.8 0.6 0.028 13.3 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EGO19954.1 - 0.00027 20.1 10.8 0.063 12.3 0.3 3.7 3 1 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 EGO19954.1 - 0.00049 19.7 2.9 0.062 12.8 0.1 3.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1967 PF09269.6 EGO19954.1 - 0.17 11.6 0.8 0.67 9.6 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Lycopene_cycl PF05834.7 EGO19954.1 - 0.22 10.4 6.8 0.37 9.6 0.1 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein THF_DHG_CYH_C PF02882.14 EGO19954.1 - 0.39 9.7 4.4 0.51 9.3 0.2 2.8 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_9 PF13454.1 EGO19954.1 - 0.47 10.2 4.9 16 5.2 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EGO19954.1 - 2.2 7.8 5.9 0.31 10.6 0.7 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EGO19956.1 - 8.2e-33 113.6 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO19956.1 - 3.4e-08 32.8 0.0 7e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO19956.1 - 1.4e-05 24.2 0.0 0.0074 15.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGO19956.1 - 0.00059 19.6 0.3 0.0011 18.7 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO19956.1 - 0.0088 15.1 0.0 0.022 13.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family GAS PF13851.1 EGO19958.1 - 0.0034 16.6 14.9 0.14 11.2 0.7 3.3 3 0 0 3 3 3 3 Growth-arrest specific micro-tubule binding DUF970 PF06153.6 EGO19958.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF970) DUF4047 PF13256.1 EGO19958.1 - 0.23 11.4 6.1 0.2 11.6 0.3 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4047) Cep57_MT_bd PF06657.8 EGO19958.1 - 1 9.3 8.6 39 4.2 0.0 4.4 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Rab5-bind PF09311.6 EGO19958.1 - 2.1 8.1 20.1 0.27 11.1 1.8 3.5 3 0 0 3 3 3 0 Rabaptin-like protein Kinetocho_Slk19 PF12709.2 EGO19958.1 - 7.4 6.7 10.7 4.5 7.4 0.0 4.2 3 2 2 5 5 5 0 Central kinetochore-associated CENP-Q PF13094.1 EGO19958.1 - 7.4 6.5 23.0 2.8 7.9 3.9 3.7 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4064 PF13273.1 EGO19959.1 - 0.0026 17.8 0.8 0.96 9.5 1.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) MARVEL PF01284.18 EGO19959.1 - 0.0054 16.5 10.4 0.037 13.8 4.5 2.2 2 0 0 2 2 2 1 Membrane-associating domain DUF1469 PF07332.6 EGO19959.1 - 0.073 12.7 0.1 0.073 12.7 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) DivIC PF04977.10 EGO19959.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF1049 PF06305.6 EGO19959.1 - 0.3 10.6 0.1 0.3 10.6 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) DUF3021 PF11457.3 EGO19959.1 - 0.89 9.4 7.5 0.19 11.6 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) DUF4293 PF14126.1 EGO19959.1 - 1.2 9.0 8.7 0.41 10.5 4.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Lig_chan PF00060.21 EGO19959.1 - 3 7.5 7.2 1.2 8.8 1.8 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel MgtE PF01769.11 EGO19963.1 - 0.01 16.1 1.3 0.01 16.1 0.9 2.2 3 0 0 3 3 3 0 Divalent cation transporter DPBB_1 PF03330.13 EGO19964.1 - 2.2e-07 30.7 0.0 4.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EGO19964.1 - 0.0056 16.6 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EGO19964.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Barwin family DPBB_1 PF03330.13 EGO19965.1 - 3.4e-11 42.9 1.8 1.3e-10 41.1 1.3 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EGO19965.1 - 0.00081 19.3 0.2 0.0012 18.8 0.2 1.5 1 1 0 1 1 1 1 Cerato-platanin TPR_11 PF13414.1 EGO19967.1 - 2.4e-15 55.8 2.6 5.2e-15 54.8 1.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGO19967.1 - 7.5e-06 25.4 1.8 0.12 12.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO19967.1 - 0.0015 18.0 2.8 0.81 9.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO19967.1 - 0.011 15.8 0.1 15 6.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO19967.1 - 0.15 11.9 1.2 0.97 9.4 0.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Suc_Fer-like PF06999.7 EGO19968.1 - 9.6e-31 107.5 0.0 1.1e-30 107.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like ACR_tran PF00873.14 EGO19968.1 - 0.0058 14.1 0.0 0.0076 13.7 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Lactonase PF10282.4 EGO19969.1 - 1.4e-32 113.1 0.0 1.6e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller zf-C3HC4_3 PF13920.1 EGO19970.1 - 5.4e-05 22.7 11.6 0.00011 21.8 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO19970.1 - 0.00087 19.0 15.1 0.0018 18.0 10.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO19970.1 - 0.0028 17.6 15.9 0.0055 16.6 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO19970.1 - 0.003 17.2 13.5 0.0063 16.2 9.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO19970.1 - 0.0044 16.6 14.4 0.0085 15.7 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Bcr-Abl_Oligo PF09036.5 EGO19970.1 - 0.05 13.5 1.6 0.78 9.7 0.1 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain zf-RING_4 PF14570.1 EGO19970.1 - 0.11 12.0 9.5 0.22 11.1 6.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGO19970.1 - 0.5 10.1 11.0 0.68 9.6 4.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Baculo_IE-1 PF05290.6 EGO19970.1 - 1 9.0 11.2 0.18 11.5 3.9 2.2 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EGO19970.1 - 1.5 8.7 14.7 3.2 7.7 10.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TMF_DNA_bd PF12329.3 EGO19970.1 - 2.3 8.0 10.5 2.8 7.8 1.6 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EGO19970.1 - 7.4 4.8 10.7 13 4.0 7.4 1.4 1 1 0 1 1 1 0 AAA domain HTH_31 PF13560.1 EGO19971.1 - 9.2e-06 25.7 0.4 1.4e-05 25.1 0.3 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EGO19971.1 - 0.00033 20.4 0.1 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.7 EGO19971.1 - 0.027 13.9 0.6 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EGO19971.1 - 0.027 13.9 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_19 PF12844.2 EGO19971.1 - 0.041 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S11 PF00411.14 EGO19972.1 - 1.6e-40 137.7 0.5 1.9e-40 137.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Acyltransferase PF01553.16 EGO19973.1 - 3.1e-14 52.5 0.0 5.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zf-RING_2 PF13639.1 EGO19976.1 - 1.4e-08 34.4 7.9 2.4e-08 33.6 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EGO19976.1 - 1.8e-08 33.9 1.4 2.9e-08 33.3 0.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EGO19976.1 - 2e-08 33.7 5.0 3.2e-08 33.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO19976.1 - 2.4e-08 33.5 7.6 3.8e-08 32.9 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO19976.1 - 1.9e-06 27.3 6.8 4.2e-06 26.3 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO19976.1 - 3.1e-06 27.0 7.7 5.1e-06 26.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO19976.1 - 0.00024 20.8 7.4 0.0015 18.3 5.5 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGO19976.1 - 0.0014 18.3 0.2 0.0014 18.3 0.2 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGO19976.1 - 0.0022 18.0 4.3 0.0037 17.3 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger DUF1272 PF06906.6 EGO19976.1 - 0.003 17.3 3.7 0.005 16.6 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-RING_4 PF14570.1 EGO19976.1 - 0.0041 16.6 2.8 0.0041 16.6 1.9 1.8 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGO19976.1 - 0.0055 16.2 5.2 0.011 15.2 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Pro_CA PF00484.14 EGO19976.1 - 0.011 15.6 0.1 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Carbonic anhydrase FYVE PF01363.16 EGO19976.1 - 0.013 15.4 7.7 0.044 13.6 1.3 2.4 2 1 1 3 3 3 0 FYVE zinc finger DUF2321 PF10083.4 EGO19976.1 - 0.017 14.6 3.7 1.4 8.4 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Baculo_IE-1 PF05290.6 EGO19976.1 - 0.018 14.7 1.6 0.032 13.9 1.1 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TerY-C PF15616.1 EGO19976.1 - 0.1 12.5 2.7 0.15 12.0 1.9 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zinc_ribbon_5 PF13719.1 EGO19976.1 - 0.42 10.2 0.0 0.42 10.2 0.0 2.4 3 0 0 3 3 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGO19976.1 - 0.47 10.1 0.0 0.47 10.1 0.0 2.4 3 0 0 3 3 2 0 zinc-ribbon domain zf-HIT PF04438.11 EGO19976.1 - 0.62 9.7 5.8 1.1 8.9 2.0 2.3 2 0 0 2 2 2 0 HIT zinc finger Prok-RING_2 PF14445.1 EGO19976.1 - 1.4 8.9 7.4 2.8 7.9 0.0 2.5 2 1 1 3 3 2 0 Prokaryotic RING finger family 2 zf-H2C2_2 PF13465.1 EGO19976.1 - 2.3 8.6 4.7 10 6.5 1.2 2.8 2 1 0 2 2 2 0 Zinc-finger double domain Synaptobrevin PF00957.16 EGO19978.1 - 3.5e-30 103.4 0.8 4.8e-30 103.0 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGO19978.1 - 2.5e-22 78.2 0.0 4e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec61_beta PF03911.11 EGO19979.1 - 2e-18 65.8 0.5 2.6e-18 65.5 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family DNA_pol_A_exo1 PF01612.15 EGO19980.1 - 1.5e-10 40.8 0.0 2.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Euplotes_phero PF05842.6 EGO19981.1 - 0.48 10.7 10.6 0.95 9.8 7.3 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Profilin PF00235.14 EGO19982.1 - 5.5e-41 139.4 0.6 6.1e-41 139.3 0.4 1.0 1 0 0 1 1 1 1 Profilin ALS2CR8 PF15299.1 EGO19983.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DDE_3 PF13358.1 EGO19984.1 - 1.9e-08 34.1 0.0 7.8e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease STE3 PF02076.10 EGO19986.1 - 1.3e-74 250.8 12.9 1.6e-74 250.5 8.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor NACHT PF05729.7 EGO19987.1 - 4e-08 33.0 0.0 8.4e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGO19987.1 - 2.1e-07 31.1 0.0 3.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO19987.1 - 5.1e-06 26.5 0.1 1.5e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EGO19987.1 - 7.2e-06 25.0 0.1 1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EGO19987.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EGO19987.1 - 0.0034 16.4 0.2 2.1 7.2 0.3 2.1 1 1 1 2 2 2 2 KAP family P-loop domain DUF2075 PF09848.4 EGO19987.1 - 0.0062 15.5 0.0 0.0095 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EGO19987.1 - 0.0067 16.6 0.2 0.036 14.2 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGO19987.1 - 0.0075 15.4 0.1 0.02 13.9 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 EGO19987.1 - 0.0093 15.3 0.1 0.023 14.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO19987.1 - 0.02 14.6 0.1 0.13 12.0 0.1 2.1 1 1 0 1 1 1 0 Part of AAA domain SQS_PSY PF00494.14 EGO19987.1 - 0.031 13.5 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase RNA_helicase PF00910.17 EGO19987.1 - 0.056 13.6 0.1 0.31 11.2 0.0 2.1 1 1 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EGO19987.1 - 0.062 13.6 0.1 0.47 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EGO19987.1 - 0.068 12.6 0.0 0.32 10.4 0.0 2.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGO19987.1 - 0.12 13.2 0.2 0.43 11.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain SRI PF08236.6 EGO19987.1 - 0.33 10.9 3.0 0.75 9.7 0.7 2.5 2 1 0 2 2 1 0 SRI (Set2 Rpb1 interacting) domain FHA PF00498.21 EGO19990.1 - 2.5e-16 59.5 0.0 4.3e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-rbx1 PF12678.2 EGO19990.1 - 4.7e-08 33.0 0.5 6.9e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGO19990.1 - 2.9e-06 26.8 3.8 6.2e-06 25.7 2.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO19990.1 - 3.7e-06 26.6 10.6 1.9e-05 24.4 7.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EGO19990.1 - 9e-06 25.4 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EGO19990.1 - 3.9e-05 23.3 0.4 3.9e-05 23.3 0.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO19990.1 - 0.0014 18.6 1.5 0.0014 18.6 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EGO19990.1 - 0.004 16.8 0.6 0.004 16.8 0.4 1.8 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_4 PF15227.1 EGO19990.1 - 0.017 14.9 1.3 0.037 13.9 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EGO19990.1 - 0.027 14.1 8.4 0.15 11.7 5.8 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDV3 PF15359.1 EGO19991.1 - 1.7 8.7 10.0 2.5 8.1 6.9 1.4 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF4655 PF15548.1 EGO19992.1 - 0.11 11.3 3.2 0.13 11.1 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4655) PepSY_TM_1 PF13172.1 EGO19993.1 - 4.2 7.2 7.9 2.4 8.0 3.3 2.2 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO19994.1 - 2.8e-08 33.2 1.1 4e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO19994.1 - 0.076 12.6 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO19994.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_11 PF08241.7 EGO19995.1 - 1.7e-18 66.9 0.0 3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO19995.1 - 2.1e-10 41.1 0.0 5.6e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO19995.1 - 2.4e-10 40.6 0.0 4.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO19995.1 - 9.4e-10 38.8 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO19995.1 - 4.2e-09 36.1 0.0 7.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO19995.1 - 7.7e-08 31.7 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGO19995.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO19995.1 - 7.7e-05 22.7 0.1 0.00025 21.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO19995.1 - 0.00046 19.6 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 EGO19995.1 - 0.12 11.9 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Fer2_3 PF13085.1 EGO19996.1 - 2.7e-31 107.6 0.0 4.1e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EGO19996.1 - 2.7e-11 43.6 8.1 2.7e-11 43.6 5.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGO19996.1 - 1.7e-08 34.3 5.8 1.7e-08 34.3 4.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGO19996.1 - 8.3e-05 22.3 5.5 8.3e-05 22.3 3.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGO19996.1 - 0.00015 22.0 3.3 0.00015 22.0 2.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGO19996.1 - 0.00017 21.8 4.4 0.056 13.7 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGO19996.1 - 0.00034 20.9 4.6 0.00034 20.9 3.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EGO19996.1 - 0.0023 17.6 3.4 0.0037 16.9 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EGO19996.1 - 0.84 10.2 6.5 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Abhydrolase_6 PF12697.2 EGO19997.1 - 2.1e-13 50.7 2.3 2.3e-13 50.5 1.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO19997.1 - 4.6e-11 42.6 0.3 5.8e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO19997.1 - 1e-08 34.9 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EGO19997.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EGO19997.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme STE3 PF02076.10 EGO19998.1 - 1.4e-61 208.0 13.6 2.5e-33 115.3 0.1 2.1 1 1 1 2 2 2 2 Pheromone A receptor MBT PF02820.13 EGO19998.1 - 0.054 13.4 0.3 5.1 7.0 0.1 2.4 2 0 0 2 2 2 0 mbt repeat DUF443 PF04276.7 EGO19998.1 - 0.59 9.5 5.6 1.3 8.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF443) HET PF06985.6 EGO19999.1 - 2.5e-16 60.1 0.0 4.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M14 PF00246.19 EGO20001.1 - 5.4e-63 213.2 0.0 6.5e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase NUC153 PF08159.7 EGO20002.1 - 4.5e-13 48.5 1.1 4.5e-13 48.5 0.8 4.6 5 1 0 5 5 5 2 NUC153 domain AhpC-TSA PF00578.16 EGO20003.1 - 4.2e-26 91.0 0.0 5.5e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO20003.1 - 6.1e-19 68.0 0.0 9.1e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.13 EGO20003.1 - 0.35 11.5 10.3 0.71 10.6 7.1 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 LRR_6 PF13516.1 EGO20004.1 - 3.3e-12 45.1 13.7 2.1 8.6 0.2 8.7 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.2 EGO20004.1 - 1.4e-09 37.3 15.9 0.0003 20.3 0.3 6.2 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO20004.1 - 1.2e-05 24.6 13.5 17 5.9 0.0 9.0 9 2 1 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 EGO20004.1 - 0.0016 18.2 16.2 24 5.7 0.0 8.7 9 0 0 9 9 9 1 Leucine rich repeat LRR_8 PF13855.1 EGO20004.1 - 0.0097 15.6 3.2 0.0097 15.6 2.2 5.4 3 2 3 6 6 6 3 Leucine rich repeat GST_N_3 PF13417.1 EGO20005.1 - 8.1e-07 29.1 0.2 1.6e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO20005.1 - 1e-05 25.4 0.1 2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO20005.1 - 0.18 11.6 0.6 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2422 PF10337.4 EGO20006.1 - 5.8e-80 269.3 0.0 6.8e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EGO20007.1 - 5.2e-29 101.4 0.3 7.7e-29 100.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EGO20007.1 - 1.3e-09 38.0 14.5 2.2e-09 37.3 10.0 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGO20007.1 - 0.00091 17.7 3.0 0.0021 16.5 2.1 1.7 1 1 0 1 1 1 1 Fusaric acid resistance protein family Swi5 PF07061.6 EGO20007.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Swi5 Aldedh PF00171.17 EGO20009.1 - 2e-171 570.4 0.4 2.3e-171 570.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UvrD_C PF13361.1 EGO20010.1 - 1.2e-12 48.0 2.2 2.6e-10 40.2 0.0 3.3 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 EGO20010.1 - 5.7e-06 26.4 0.7 0.0005 20.1 0.1 3.7 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EGO20010.1 - 1.8e-05 24.1 2.8 0.0025 17.1 0.1 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_12 PF13087.1 EGO20010.1 - 0.0025 17.2 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO20010.1 - 0.013 15.6 0.1 3.3 7.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain TPR_2 PF07719.12 EGO20010.1 - 0.16 11.9 3.3 4.6 7.4 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO20010.1 - 0.4 10.3 4.9 8.7 6.0 0.0 3.7 3 1 0 3 3 3 0 TPR repeat Methyltransf_18 PF12847.2 EGO20011.1 - 2e-12 47.6 0.0 5e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO20011.1 - 5.4e-07 29.3 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO20011.1 - 1.5e-06 27.9 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EGO20011.1 - 9.7e-06 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO20011.1 - 1.9e-05 25.0 0.0 4.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO20011.1 - 2.5e-05 23.5 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGO20011.1 - 8.4e-05 22.9 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGO20011.1 - 9.5e-05 23.1 0.0 0.00021 22.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO20011.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGO20011.1 - 0.0058 15.6 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EGO20011.1 - 0.0089 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 EGO20011.1 - 0.0092 15.9 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase MCP_N PF05581.7 EGO20011.1 - 0.017 15.2 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus CMAS PF02353.15 EGO20011.1 - 0.021 13.8 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EGO20011.1 - 0.056 12.8 0.3 0.28 10.6 0.2 2.0 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EGO20011.1 - 0.068 13.2 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGO20011.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PTR2 PF00854.16 EGO20012.1 - 1.5e-45 155.6 17.1 1.2e-44 152.5 11.9 2.1 1 1 0 1 1 1 1 POT family dsrm PF00035.20 EGO20013.1 - 2.9e-09 37.3 0.0 4e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Double-stranded RNA binding motif FlgM PF04316.8 EGO20014.1 - 0.63 10.0 18.7 2.3e+02 1.7 0.0 9.9 6 5 6 12 12 12 0 Anti-sigma-28 factor, FlgM Abhydrolase_3 PF07859.8 EGO20015.1 - 3.3e-51 173.8 0.0 4.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO20015.1 - 0.0014 17.3 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Glyco_transf_15 PF01793.11 EGO20016.1 - 6.1e-124 413.2 12.8 6.9e-124 413.0 8.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIR2 PF02146.12 EGO20018.1 - 3.9e-35 121.1 0.0 6.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EGO20018.1 - 0.058 13.1 0.1 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pex19 PF04614.7 EGO20019.1 - 1.1e-51 175.8 2.7 1.9e-51 175.0 1.9 1.3 1 1 0 1 1 1 1 Pex19 protein family Lyase_8 PF02278.13 EGO20020.1 - 6.4e-32 110.9 0.1 1.3e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 EGO20020.1 - 2.1e-17 63.0 0.0 3.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 EGO20020.1 - 0.0019 18.2 0.4 0.0068 16.4 0.3 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DUF763 PF05559.6 EGO20020.1 - 0.13 11.1 0.1 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF763) TRAM_LAG1_CLN8 PF03798.11 EGO20022.1 - 0.0002 20.9 20.4 0.0003 20.4 14.1 1.4 1 1 0 1 1 1 1 TLC domain Fig1 PF12351.3 EGO20022.1 - 0.33 10.8 6.5 0.086 12.7 1.1 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Ndc1_Nup PF09531.5 EGO20023.1 - 6.9e-59 199.8 0.9 8e-59 199.6 0.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup AAA PF00004.24 EGO20024.1 - 8.3e-75 249.2 0.0 1.6e-40 138.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO20024.1 - 1e-11 44.3 0.0 0.00038 19.5 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGO20024.1 - 2.6e-11 43.4 0.0 1.5e-05 24.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO20024.1 - 3.2e-11 43.5 0.4 1.5e-05 25.0 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGO20024.1 - 1.9e-10 40.9 0.0 3.1e-05 24.1 0.0 4.3 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO20024.1 - 7.3e-09 35.7 0.0 0.00067 19.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGO20024.1 - 2.6e-08 33.4 0.0 0.00023 20.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO20024.1 - 6.5e-08 31.9 0.0 0.00011 21.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EGO20024.1 - 6.7e-08 32.4 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGO20024.1 - 1.2e-07 30.8 0.0 0.0022 16.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 EGO20024.1 - 1.6e-07 31.2 0.0 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO20024.1 - 5.5e-07 29.2 0.3 0.00096 18.8 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EGO20024.1 - 6.7e-07 30.1 0.0 0.0001 23.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGO20024.1 - 1.7e-06 27.5 1.3 0.39 10.1 0.0 4.1 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.17 EGO20024.1 - 0.00012 22.1 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EGO20024.1 - 0.00023 20.3 0.3 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGO20024.1 - 0.00037 20.5 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EGO20024.1 - 0.00053 19.9 0.0 0.072 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO20024.1 - 0.00094 19.4 0.0 0.0036 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EGO20024.1 - 0.00095 18.8 0.0 0.088 12.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DAP3 PF10236.4 EGO20024.1 - 0.0023 16.9 0.0 0.0093 14.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.1 EGO20024.1 - 0.0031 17.1 0.0 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EGO20024.1 - 0.0037 16.7 0.0 0.024 14.1 0.0 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.6 EGO20024.1 - 0.0053 16.3 0.0 0.9 9.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EGO20024.1 - 0.0061 15.8 0.0 0.5 9.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 EGO20024.1 - 0.0061 16.0 0.0 0.89 9.0 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EGO20024.1 - 0.0079 15.8 0.0 0.58 9.7 0.0 2.7 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 EGO20024.1 - 0.0082 15.8 0.0 0.56 9.8 0.0 2.9 3 0 0 3 3 3 1 Bacterial dnaA protein Viral_helicase1 PF01443.13 EGO20024.1 - 0.0096 15.4 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EGO20024.1 - 0.013 15.8 0.1 0.23 11.7 0.0 2.7 3 0 0 3 3 2 0 ABC transporter AAA_24 PF13479.1 EGO20024.1 - 0.016 14.8 0.1 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO20024.1 - 0.022 14.4 0.0 12 5.4 0.0 3.6 2 2 2 4 4 4 0 Archaeal ATPase KaiC PF06745.8 EGO20024.1 - 0.024 13.7 0.0 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 EGO20024.1 - 0.059 12.2 0.0 3.4 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 EGO20024.1 - 0.064 12.1 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EGO20024.1 - 0.093 11.4 0.0 2.6 6.5 0.0 2.4 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EGO20024.1 - 0.11 12.1 0.2 2.2 7.9 0.0 2.9 2 2 0 3 3 3 0 NTPase Tim17 PF02466.14 EGO20025.1 - 1.9e-22 79.7 0.2 3.3e-22 78.8 0.1 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF957 PF06117.6 EGO20026.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) DTHCT PF08070.6 EGO20026.1 - 8.3 7.1 9.3 0.56 10.8 2.5 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region gag-asp_proteas PF13975.1 EGO20027.1 - 6.1e-08 32.3 0.0 8.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO20027.1 - 2.5e-07 30.7 0.0 2.7e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO20027.1 - 9.3e-05 22.8 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease p47_phox_C PF08944.6 EGO20029.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Nicastrin PF05450.10 EGO20029.1 - 0.095 11.9 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Nicastrin SKN1 PF03935.10 EGO20033.1 - 3.2e-184 612.7 5.4 3.9e-184 612.4 3.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) LysR_substrate PF03466.15 EGO20034.1 - 0.031 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain SBP_bac_8 PF13416.1 EGO20034.1 - 0.036 13.7 0.5 0.7 9.5 0.0 2.2 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein Redoxin PF08534.5 EGO20035.1 - 3.3e-40 136.9 0.0 3.8e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGO20035.1 - 3e-14 52.7 0.0 3.8e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1469 PF07332.6 EGO20036.1 - 0.0063 16.2 0.1 0.0089 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) UPF0270 PF06794.7 EGO20036.1 - 0.093 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) N_NLPC_P60 PF12912.2 EGO20036.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term DUF761 PF05553.6 EGO20036.1 - 0.43 9.9 2.2 0.34 10.3 0.3 1.8 2 0 0 2 2 2 0 Cotton fibre expressed protein NAD_binding_6 PF08030.7 EGO20038.1 - 1.8e-17 63.6 0.0 1.5e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO20038.1 - 3e-16 59.1 0.0 2.7e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 EGO20038.1 - 5.5e-15 55.5 8.0 5.5e-15 55.5 5.5 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component TcpE PF12648.2 EGO20038.1 - 0.36 10.9 7.8 2.4 8.3 0.1 3.5 3 0 0 3 3 3 0 TcpE family adh_short PF00106.20 EGO20039.1 - 1.1e-33 116.4 1.1 1.5e-33 116.0 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO20039.1 - 1e-24 87.6 0.1 1.3e-24 87.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO20039.1 - 1.5e-14 54.1 0.4 2.3e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 KR domain VBS PF08913.5 EGO20039.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Vinculin Binding Site adh_short PF00106.20 EGO20040.1 - 1.7e-31 109.3 4.1 2.2e-31 109.0 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO20040.1 - 2.4e-27 96.2 0.2 2.9e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO20040.1 - 5.2e-13 49.0 2.9 7.8e-13 48.4 2.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO20040.1 - 0.0024 17.3 0.6 0.0048 16.3 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGO20040.1 - 0.02 14.5 0.2 0.034 13.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VBS PF08913.5 EGO20040.1 - 0.065 13.4 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Vinculin Binding Site NAD_binding_10 PF13460.1 EGO20040.1 - 0.082 12.8 1.2 0.2 11.6 0.5 1.9 1 1 0 1 1 1 0 NADH(P)-binding DUF569 PF04601.8 EGO20041.1 - 0.048 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF569) F-box-like PF12937.2 EGO20042.1 - 0.00052 19.6 0.0 0.002 17.8 0.0 2.1 2 1 0 2 2 2 1 F-box-like Solute_trans_a PF03619.11 EGO20043.1 - 8.6e-99 330.2 8.7 1e-98 330.0 6.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 7TM_transglut PF14402.1 EGO20043.1 - 0.12 11.3 3.3 0.19 10.5 2.3 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF566 PF04484.7 EGO20044.1 - 1.7 8.0 7.9 1.7 8.1 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Lyase_8 PF02278.13 EGO20045.1 - 3.5e-31 108.5 0.8 3.5e-31 108.5 0.6 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 EGO20045.1 - 7.2e-24 84.2 0.1 1.1e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 EGO20045.1 - 0.0033 17.3 0.1 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Spt5-NGN PF03439.8 EGO20045.1 - 0.063 13.0 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section Glyco_hydro_1 PF00232.13 EGO20047.1 - 1.2e-20 73.1 0.0 1.4e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Baculo_PEP_N PF04512.7 EGO20047.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, N terminus Hemerythrin PF01814.18 EGO20048.1 - 9e-14 51.7 1.5 1.3e-13 51.2 1.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short PF00106.20 EGO20050.1 - 5.8e-21 75.1 0.6 9.9e-21 74.3 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO20050.1 - 8.5e-13 48.6 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO20050.1 - 7e-08 32.6 0.0 1.6e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO20050.1 - 3e-05 23.7 0.2 5.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO20050.1 - 0.0033 16.9 0.0 0.0054 16.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO20050.1 - 0.043 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DPBB_1 PF03330.13 EGO20052.1 - 2.3e-14 53.1 0.1 4.1e-14 52.3 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EGO20052.1 - 0.0042 17.0 0.0 0.0087 16.0 0.0 1.5 1 1 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EGO20052.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 Barwin family DPBB_1 PF03330.13 EGO20054.1 - 4.3e-14 52.2 0.8 1.5e-13 50.5 0.6 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EGO20054.1 - 0.0031 17.4 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.13 EGO20056.1 - 1.6e-11 44.0 1.0 6.2e-11 42.1 0.7 2.2 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EGO20056.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Cerato-platanin AhpC-TSA PF00578.16 EGO20057.1 - 4.9e-33 113.4 0.0 6.4e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO20057.1 - 2.2e-13 49.9 0.0 2.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EGO20057.1 - 5.9e-12 45.0 0.0 1.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin TIM PF00121.13 EGO20058.1 - 1.9e-89 298.9 0.1 2.1e-89 298.7 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EGO20058.1 - 0.0063 15.8 0.0 0.012 14.8 0.0 1.5 1 1 0 1 1 1 1 CutC family Aldedh PF00171.17 EGO20059.1 - 1e-84 284.5 0.0 1.4e-84 284.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO20059.1 - 0.00047 18.9 0.0 0.0018 17.0 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Alpha_kinase PF02816.13 EGO20062.1 - 2.6e-12 46.8 0.0 3.1e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Pil1 PF13805.1 EGO20068.1 - 3.1e-24 85.5 0.3 6.1e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 MMTV_SAg PF01054.12 EGO20068.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen HR1 PF02185.11 EGO20068.1 - 0.19 11.4 5.7 0.1 12.3 1.7 2.2 2 0 0 2 2 2 0 Hr1 repeat Terpene_synth_C PF03936.11 EGO20070.1 - 4.9e-10 39.0 0.0 1.7e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Methyltransf_2 PF00891.13 EGO20071.1 - 4e-27 94.9 0.0 3.7e-25 88.5 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase RPA_C PF08784.6 EGO20071.1 - 8.3e-06 26.1 0.0 5e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Replication protein A C terminal Methyltransf_16 PF10294.4 EGO20071.1 - 0.00026 20.4 0.0 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO20071.1 - 0.0034 17.9 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO20071.1 - 0.0085 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.5 EGO20071.1 - 0.13 11.8 0.1 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain Methyltransf_32 PF13679.1 EGO20071.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EGO20075.1 - 5.1e-19 68.1 35.4 3.4e-10 39.1 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGO20075.1 - 0.0078 14.7 17.3 0.023 13.1 11.8 1.8 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1664 PF07889.7 EGO20075.1 - 0.16 11.7 0.1 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MFS_1_like PF12832.2 EGO20075.1 - 0.6 9.9 0.0 0.6 9.9 0.0 3.9 3 2 0 3 3 3 0 MFS_1 like family Beach PF02138.13 EGO20076.1 - 3.6e-74 249.6 0.0 6e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EGO20076.1 - 8.9e-11 41.2 5.1 5.4e-05 22.9 0.7 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.1 EGO20076.1 - 2.1e-08 33.9 0.0 7.5e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EGO20076.1 - 1e-05 25.7 0.1 2.8e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CDC14 PF08045.6 EGO20076.1 - 0.021 13.9 0.7 0.082 12.0 0.0 2.2 3 0 0 3 3 3 0 Cell division control protein 14, SIN component DUF3159 PF11361.3 EGO20077.1 - 0.048 13.1 0.1 0.061 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) DUF3527 PF12043.3 EGO20080.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Spore_YpjB PF09577.5 EGO20081.1 - 0.076 12.5 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF1426 PF07234.6 EGO20082.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) gpUL132 PF11359.3 EGO20082.1 - 0.41 9.9 4.9 0.18 11.0 0.3 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 p450 PF00067.17 EGO20083.1 - 1.5e-75 254.4 0.0 1.7e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EGO20084.1 - 1.4e-59 201.6 0.0 1.9e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO20084.1 - 2.2e-30 105.8 0.0 9e-26 90.8 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_3 PF13738.1 EGO20084.1 - 1.9e-05 24.8 0.4 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO20084.1 - 2.9e-05 23.1 0.1 0.002 17.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO20084.1 - 8.9e-05 21.5 1.0 0.0035 16.2 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 EGO20084.1 - 0.0013 17.7 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO20084.1 - 0.0015 18.4 1.7 0.0021 18.0 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO20084.1 - 0.0036 17.1 0.3 0.059 13.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO20084.1 - 0.14 10.5 0.8 0.27 9.6 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein STE3 PF02076.10 EGO20085.1 - 1.2e-73 247.6 13.4 1.4e-73 247.4 9.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor adh_short PF00106.20 EGO20086.1 - 1.2e-11 44.8 0.1 2.6e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20086.1 - 2.7e-07 30.4 0.1 4.4e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO20086.1 - 5e-05 23.3 1.1 0.00038 20.5 0.8 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EGO20086.1 - 0.00086 19.1 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGO20086.1 - 0.0016 17.9 0.1 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 EGO20086.1 - 0.0059 16.8 0.1 0.17 12.1 0.1 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGO20086.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.10 EGO20086.1 - 0.03 13.9 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus NmrA PF05368.8 EGO20086.1 - 0.094 11.9 0.1 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family RNase_P_p30 PF01876.11 EGO20087.1 - 1.9e-28 98.6 0.0 3.8e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit p30 adh_short PF00106.20 EGO20088.1 - 4.9e-23 81.8 0.0 7.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO20088.1 - 6.6e-20 71.9 0.0 8.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO20088.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGO20088.1 - 0.00099 18.3 0.0 0.0077 15.4 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) PAE PF03283.8 EGO20088.1 - 0.03 12.9 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase NAD_binding_10 PF13460.1 EGO20088.1 - 0.03 14.3 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_6 PF08030.7 EGO20091.1 - 1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO20091.1 - 3e-17 62.4 0.0 9e-16 57.6 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGO20091.1 - 4.3e-16 59.1 8.5 7.8e-16 58.3 5.9 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EGO20091.1 - 0.15 12.6 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Oxidored_FMN PF00724.15 EGO20092.1 - 1.5e-101 339.8 0.0 1.7e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EGO20093.1 - 1.1e-94 317.2 0.0 1.2e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2267 PF10025.4 EGO20093.1 - 0.065 13.2 0.0 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Transaldolase PF00923.14 EGO20094.1 - 4.3e-93 311.5 0.0 4.9e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase GMC_oxred_N PF00732.14 EGO20095.1 - 1.6e-19 70.1 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO20095.1 - 4.8e-18 65.8 0.0 1.5e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EGO20095.1 - 3.3e-08 32.8 0.3 8.5e-05 21.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO20095.1 - 2.4e-06 26.6 0.1 5.7e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGO20095.1 - 2.1e-05 24.4 0.1 6.5e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO20095.1 - 5.8e-05 22.3 0.0 0.00016 20.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO20095.1 - 6.6e-05 22.1 0.2 0.0021 17.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO20095.1 - 0.00015 20.4 0.1 0.00025 19.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EGO20095.1 - 0.00018 20.6 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO20095.1 - 0.00025 20.9 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO20095.1 - 0.0026 17.8 0.1 0.0076 16.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO20095.1 - 0.15 10.9 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxal_oxid_N PF07250.6 EGO20096.1 - 2.8e-38 131.3 0.0 1.1e-34 119.5 0.0 4.1 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGO20096.1 - 1.3e-22 79.7 1.7 3.2e-22 78.4 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.6 EGO20096.1 - 0.022 14.3 2.4 0.049 13.1 1.7 1.5 1 0 0 1 1 1 0 Podoplanin Kelch_4 PF13418.1 EGO20096.1 - 2.8 7.7 15.8 1.4 8.7 0.2 5.4 5 0 0 5 5 5 0 Galactose oxidase, central domain BNR PF02012.15 EGO20097.1 - 2.2e-09 35.7 35.6 1 9.4 0.1 9.5 9 0 0 9 9 9 7 BNR/Asp-box repeat DUF3725 PF12523.3 EGO20098.1 - 0.047 13.7 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Pyr_redox_3 PF13738.1 EGO20099.1 - 1.4e-22 80.7 0.1 5.6e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO20099.1 - 1.7e-15 56.2 0.0 9.1e-14 50.5 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO20099.1 - 2.2e-12 46.5 0.0 1.6e-10 40.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO20099.1 - 1.5e-09 38.0 0.0 6.4e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO20099.1 - 3.2e-09 36.1 4.0 0.057 12.3 0.0 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO20099.1 - 1.8e-07 31.0 1.0 2e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO20099.1 - 2.8e-06 27.2 2.6 0.12 12.1 0.1 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EGO20099.1 - 1.2e-05 25.5 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.22 EGO20099.1 - 9.2e-05 22.7 3.8 0.0054 17.1 0.4 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO20099.1 - 0.00012 21.2 1.5 0.033 13.3 0.1 2.5 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.14 EGO20099.1 - 0.0021 17.2 1.4 0.0084 15.2 0.2 2.2 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EGO20099.1 - 0.0048 15.4 5.0 0.023 13.2 0.2 3.4 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.19 EGO20099.1 - 0.012 14.5 4.6 0.034 13.0 0.4 2.9 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 EGO20099.1 - 0.019 15.0 0.2 3.1 7.9 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EGO20099.1 - 0.034 13.0 0.6 7.7 5.3 0.0 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein IlvN PF07991.7 EGO20099.1 - 0.041 13.2 0.9 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Amino_oxidase PF01593.19 EGO20099.1 - 0.062 12.3 0.9 13 4.7 0.0 3.1 3 1 0 4 4 4 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EGO20099.1 - 0.07 11.9 4.1 13 4.5 0.5 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGO20099.1 - 0.13 11.9 4.0 2.7 7.6 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGO20099.1 - 0.19 11.4 2.4 11 5.6 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EGO20099.1 - 0.36 9.8 0.0 0.36 9.8 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.21 EGO20101.1 - 1.8e-27 95.4 0.1 2.7e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO20101.1 - 1.1e-18 68.3 0.0 2.2e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO20101.1 - 6e-13 48.5 0.1 1.3e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DSRB PF10781.4 EGO20103.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Dextransucrase DSRB Ish1 PF10281.4 EGO20104.1 - 0.0096 15.9 0.5 0.02 14.9 0.3 1.6 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF2743 PF10899.3 EGO20105.1 - 0.0086 15.4 0.6 0.02 14.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2743) DUF1053 PF06327.9 EGO20106.1 - 0.075 13.3 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Pkinase PF00069.20 EGO20108.1 - 2e-09 37.0 0.0 3.4e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO20108.1 - 7e-08 31.8 0.0 4e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO20108.1 - 8e-05 22.4 0.0 0.001 18.8 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO20108.1 - 0.00037 20.1 0.0 0.0039 16.7 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EGO20108.1 - 0.002 17.1 0.0 0.0045 16.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family BRCT PF00533.21 EGO20108.1 - 0.046 13.8 0.1 15 5.7 0.0 2.7 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DDE_1 PF03184.14 EGO20109.1 - 1.9e-22 79.5 0.0 4.7e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease SAP PF02037.22 EGO20109.1 - 0.025 14.0 0.7 0.07 12.6 0.0 2.1 3 0 0 3 3 3 0 SAP domain Trehalase_Ca-bi PF07492.6 EGO20109.1 - 0.12 11.7 0.9 0.26 10.6 0.6 1.5 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain PSI PF01437.20 EGO20110.1 - 0.051 13.7 1.1 0.051 13.7 0.7 2.1 2 0 0 2 2 2 0 Plexin repeat Zn_clus PF00172.13 EGO20110.1 - 4.4 7.2 8.6 37 4.3 6.0 2.1 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.14 EGO20111.1 - 7.4e-14 50.9 0.0 1.6e-07 30.0 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain PqqD PF05402.7 EGO20111.1 - 0.00085 19.2 0.3 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) DUF3735 PF12537.3 EGO20112.1 - 1.7e-06 27.9 0.2 2.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) DUF3112 PF11309.3 EGO20112.1 - 0.015 15.0 1.7 0.019 14.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF1418 PF07214.7 EGO20112.1 - 0.063 12.9 3.3 2.3 7.9 1.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1418) SUR7 PF06687.7 EGO20112.1 - 3 7.3 9.0 0.13 11.8 1.5 1.8 1 1 1 2 2 2 0 SUR7/PalI family FA_desaturase PF00487.19 EGO20112.1 - 3.7 6.9 6.1 5.2 6.4 4.2 1.4 1 1 0 1 1 1 0 Fatty acid desaturase DUF4131 PF13567.1 EGO20112.1 - 9 5.6 9.8 6.9 6.0 5.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Pol_alpha_B_N PF08418.5 EGO20115.1 - 7.3 6.0 6.4 10 5.5 4.4 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal OrfB_Zn_ribbon PF07282.6 EGO20119.1 - 0.0022 17.6 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DUF4493 PF14900.1 EGO20119.1 - 0.047 13.3 0.2 0.051 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) 2OG-FeII_Oxy_2 PF13532.1 EGO20120.1 - 3.4e-13 49.8 0.0 1.8e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGO20120.1 - 4.9e-05 23.5 0.2 0.0014 18.9 0.2 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.17 EGO20121.1 - 1.5e-08 34.2 0.1 3.6e-08 32.9 0.1 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PEMT PF04191.8 EGO20122.1 - 8.9e-50 167.2 14.3 6.7e-28 96.8 1.3 2.8 3 0 0 3 3 3 2 Phospholipid methyltransferase PID PF00640.18 EGO20122.1 - 0.06 13.3 0.2 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Mating_N PF12731.2 EGO20122.1 - 0.066 13.0 0.0 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 Aminotran_3 PF00202.16 EGO20123.1 - 7.9e-107 357.0 0.0 1e-106 356.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGO20123.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGO20123.1 - 0.017 14.2 0.0 0.06 12.4 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase zf-DHHC PF01529.15 EGO20124.1 - 1.8e-37 128.3 6.4 5.2e-37 126.9 4.4 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF912 PF06024.7 EGO20124.1 - 0.14 12.1 2.6 2.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RNase_P_Rpp14 PF01900.14 EGO20125.1 - 0.0028 17.5 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Cullin_binding PF03556.10 EGO20126.1 - 1.2e-31 109.2 0.1 2.3e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EGO20126.1 - 2.4e-07 30.1 0.2 7e-07 28.6 0.1 1.8 1 1 0 1 1 1 1 UBA-like domain PAT1 PF09770.4 EGO20128.1 - 4.1 5.5 13.5 4.5 5.3 9.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 p450 PF00067.17 EGO20133.1 - 2.7e-62 210.7 0.0 3.6e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.7 EGO20134.1 - 0.00086 18.9 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EGO20134.1 - 0.044 13.9 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADH_zinc_N PF00107.21 EGO20136.1 - 2.8e-29 101.2 0.4 4.6e-29 100.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO20136.1 - 5.3e-20 72.6 0.7 1.2e-19 71.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO20136.1 - 9e-13 47.9 0.1 1.8e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EGO20136.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EGO20137.1 - 2e-28 99.2 0.0 3.9e-28 98.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO20137.1 - 3e-08 33.0 0.0 1.4e-07 30.8 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase MAP2_projctn PF08377.5 EGO20137.1 - 0.12 9.9 0.0 0.16 9.4 0.0 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain Fes1 PF08609.5 EGO20143.1 - 4.2e-26 91.2 1.5 2.2e-25 88.9 0.7 2.3 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EGO20143.1 - 5.6e-06 26.5 6.7 0.00055 20.1 1.4 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EGO20143.1 - 0.0026 18.2 3.7 0.62 10.6 0.2 4.0 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EGO20143.1 - 0.017 15.1 0.6 8.1 6.8 0.0 3.8 4 1 1 5 5 5 0 HEAT repeat Flagellin_N PF00669.15 EGO20143.1 - 0.052 13.3 0.7 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF4350 PF14258.1 EGO20143.1 - 0.079 13.1 0.2 1 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Chromo PF00385.19 EGO20147.1 - 3.1e-06 26.7 0.1 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EGO20148.1 - 9.3e-09 34.8 3.0 1.4e-08 34.2 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO20148.1 - 0.044 13.5 0.1 0.087 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO20148.1 - 0.17 11.5 1.0 0.27 10.9 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO20148.1 - 0.21 11.2 1.7 0.72 9.5 1.2 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EGO20148.1 - 4.1 6.9 7.1 0.39 10.2 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF2235 PF09994.4 EGO20151.1 - 1.9e-59 201.2 0.0 2.6e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EGO20151.1 - 0.0086 15.8 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4381 PF14316.1 EGO20154.1 - 0.066 13.3 0.3 0.073 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4381 PF14316.1 EGO20155.1 - 0.05 13.7 0.1 0.055 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ERG4_ERG24 PF01222.12 EGO20157.1 - 9.5e-135 449.4 7.2 1.8e-134 448.5 5.0 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EGO20157.1 - 1.9e-07 31.1 3.4 2.8e-07 30.5 0.1 3.0 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGO20157.1 - 5.5e-07 29.1 0.3 5.5e-07 29.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EGO20157.1 - 0.00045 20.3 0.4 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Glyco_hydro_71 PF03659.9 EGO20158.1 - 5.3e-100 334.5 5.3 6.3e-100 334.3 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_6 PF12697.2 EGO20160.1 - 0.0026 17.6 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Histone PF00125.19 EGO20162.1 - 1.6e-22 79.3 0.2 2.2e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO20162.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_31 PF13847.1 EGO20163.1 - 3.1e-29 101.5 0.0 4e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO20163.1 - 1.1e-25 89.8 0.0 1.8e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO20163.1 - 3.2e-18 65.9 0.0 4.5e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20163.1 - 3.7e-17 62.9 0.0 7.9e-17 61.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO20163.1 - 4.3e-16 59.1 0.0 6.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO20163.1 - 7.2e-16 57.9 0.0 1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO20163.1 - 2.2e-15 56.8 0.0 3.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO20163.1 - 9.6e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGO20163.1 - 3.5e-10 39.9 0.1 1e-09 38.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO20163.1 - 2.1e-07 30.4 0.0 3.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGO20163.1 - 4.2e-07 29.2 0.0 9.2e-07 28.0 0.0 1.6 1 1 1 2 2 2 1 Putative methyltransferase MetW PF07021.7 EGO20163.1 - 5.8e-07 29.0 0.0 8.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EGO20163.1 - 5.9e-05 21.9 0.0 8.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EGO20163.1 - 0.00078 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGO20163.1 - 0.00081 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 EGO20163.1 - 0.0014 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EGO20163.1 - 0.0024 16.7 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_29 PF03141.11 EGO20163.1 - 0.0041 15.5 0.0 0.0061 14.9 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EGO20163.1 - 0.0052 15.8 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 EGO20163.1 - 0.0053 16.3 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Phos_pyr_kin PF08543.7 EGO20163.1 - 0.0059 15.8 0.1 0.0083 15.3 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Methyltransf_32 PF13679.1 EGO20163.1 - 0.0098 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGO20163.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G adh_short PF00106.20 EGO20164.1 - 2.8e-25 89.1 0.1 3.6e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO20164.1 - 1.1e-10 41.6 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO20164.1 - 4.4e-10 39.5 0.0 7.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO20164.1 - 0.00054 20.0 0.4 0.0014 18.7 0.1 1.8 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO20164.1 - 0.0018 17.7 0.1 0.0027 17.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SUR7 PF06687.7 EGO20165.1 - 2.3e-11 43.6 15.1 7.6e-11 41.9 10.4 1.9 1 1 0 1 1 1 1 SUR7/PalI family Lysis_S PF04971.7 EGO20165.1 - 3.4 7.4 6.6 2.3 7.9 1.1 2.3 1 1 1 2 2 2 0 Lysis protein S SUR7 PF06687.7 EGO20167.1 - 1.8e-13 50.5 23.2 5.1e-13 49.0 15.6 2.0 1 1 0 1 1 1 1 SUR7/PalI family Cad PF03596.8 EGO20167.1 - 0.012 15.3 1.0 0.012 15.3 0.7 1.6 2 0 0 2 2 2 0 Cadmium resistance transporter Tetraspannin PF00335.15 EGO20167.1 - 0.048 12.9 6.5 0.067 12.4 1.6 2.2 2 0 0 2 2 2 0 Tetraspanin family DUF1673 PF07895.6 EGO20167.1 - 0.051 13.1 0.2 0.051 13.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4293 PF14126.1 EGO20167.1 - 0.55 10.1 10.2 0.14 12.0 3.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DuoxA PF10204.4 EGO20167.1 - 0.71 8.8 9.2 0.018 14.0 1.9 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF3353 PF11833.3 EGO20167.1 - 1.3 8.4 4.7 2.1 7.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Claudin_2 PF13903.1 EGO20167.1 - 1.7 8.3 21.4 0.17 11.5 9.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Cytochrom_B_C PF00032.12 EGO20167.1 - 4.1 7.6 7.3 1.7 8.8 1.6 2.3 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD IATP PF04568.7 EGO20168.1 - 3.3e-10 39.8 1.9 3.4e-10 39.8 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Bap31 PF05529.7 EGO20168.1 - 0.25 10.7 1.1 0.24 10.8 0.8 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RNA_pol PF00940.14 EGO20169.1 - 3.1e-166 552.8 0.0 4.1e-166 552.4 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGO20169.1 - 1.3e-75 254.6 0.0 2.5e-75 253.6 0.0 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Adaptin_N PF01602.15 EGO20171.1 - 5.1e-151 503.5 9.9 6.4e-151 503.2 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGO20171.1 - 1.9e-27 96.2 3.2 5e-25 88.3 0.3 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGO20171.1 - 1.1e-18 67.2 2.2 1.1e-08 35.1 0.0 5.7 2 2 4 6 6 6 6 HEAT repeats HEAT PF02985.17 EGO20171.1 - 1e-08 34.4 8.3 0.00032 20.5 0.1 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGO20171.1 - 6.9e-07 29.5 7.0 0.005 17.2 0.1 6.3 7 1 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EGO20171.1 - 0.0012 18.2 1.2 0.46 9.8 0.0 3.9 4 1 1 5 5 5 1 CLASP N terminal Arm PF00514.18 EGO20171.1 - 0.021 14.6 4.7 24 4.9 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ribonuc_P_40 PF08584.6 EGO20171.1 - 0.07 12.1 0.1 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit Glyco_hydro_30 PF02055.11 EGO20173.1 - 2.9e-25 88.4 2.0 4.6e-25 87.7 1.4 1.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Myosin_tail_1 PF01576.14 EGO20174.1 - 0.0054 14.5 0.1 0.0077 14.0 0.1 1.1 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 EGO20174.1 - 0.03 13.4 0.2 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Tropomyosin p450 PF00067.17 EGO20176.1 - 3.5e-70 236.8 0.0 4.2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO20177.1 - 2.4e-66 224.1 0.0 2.8e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1289 PF06945.8 EGO20178.1 - 0.0035 16.7 0.7 0.0075 15.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) RSN1_TM PF13967.1 EGO20179.1 - 0.072 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Mito_fiss_reg PF05308.6 EGO20179.1 - 0.1 11.9 6.8 0.15 11.4 4.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 EGO20179.1 - 0.1 11.2 1.9 0.13 10.9 1.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Epimerase PF01370.16 EGO20180.1 - 1.9e-19 70.0 0.0 2.5e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO20180.1 - 7.8e-09 34.8 0.0 1.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EGO20180.1 - 4.1e-07 30.0 0.1 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO20180.1 - 1.3e-06 27.3 0.0 1.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO20180.1 - 2.8e-06 26.4 0.0 5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO20180.1 - 0.00055 19.9 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO20180.1 - 0.016 14.8 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EGO20180.1 - 0.053 12.4 0.0 1.5 7.6 0.0 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Kelch_4 PF13418.1 EGO20187.1 - 4.6e-46 154.3 17.5 1.6e-09 37.4 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGO20187.1 - 8.9e-43 143.5 12.4 7.6e-08 32.3 0.0 7.0 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO20187.1 - 3.6e-35 119.3 13.1 2.5e-08 33.6 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EGO20187.1 - 7.3e-31 105.4 14.6 3.7e-06 26.3 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGO20187.1 - 1.8e-30 103.8 14.8 1.6e-07 31.2 0.0 6.5 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGO20187.1 - 8.6e-23 79.1 12.9 2.5e-05 23.8 0.1 6.5 6 0 0 6 6 6 6 Kelch motif SMP PF04927.7 EGO20188.1 - 1.2e-05 25.1 7.8 0.0017 18.2 0.7 3.0 2 1 0 2 2 2 2 Seed maturation protein Es2 PF09751.4 EGO20189.1 - 1.7e-61 208.9 5.2 1.1e-50 173.2 1.1 2.1 1 1 1 2 2 2 2 Nuclear protein Es2 SUI1 PF01253.17 EGO20190.1 - 1.4e-10 40.8 0.4 4.5e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.15 EGO20190.1 - 3.5e-05 23.4 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 PUA domain RrnaAD PF00398.15 EGO20191.1 - 4.5e-57 193.0 0.0 6.1e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGO20191.1 - 9.1e-11 41.8 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20191.1 - 8e-07 29.6 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO20191.1 - 4.2e-05 22.9 0.0 7.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGO20191.1 - 7.7e-05 22.3 0.0 0.00027 20.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO20191.1 - 0.00016 22.1 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO20191.1 - 0.0003 20.5 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO20191.1 - 0.00043 20.7 0.0 0.00086 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO20191.1 - 0.00048 19.7 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EGO20191.1 - 0.00079 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EGO20191.1 - 0.00095 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 EGO20191.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 EGO20191.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 EGO20191.1 - 0.081 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein NodS PF05401.6 EGO20191.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) tRNA-synt_1 PF00133.17 EGO20193.1 - 4.1e-36 124.1 0.0 8.6e-27 93.3 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGO20193.1 - 2.8e-16 59.2 0.0 1.3e-08 33.9 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGO20193.1 - 5.9e-16 58.5 0.1 8.7e-15 54.7 0.0 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGO20193.1 - 7.4e-08 31.8 0.0 1.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Oxysterol_BP PF01237.13 EGO20195.1 - 8.1e-77 258.0 0.0 1.2e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PseudoU_synth_1 PF01416.15 EGO20196.1 - 4.8e-24 84.8 0.0 2.7e-14 53.4 0.0 2.9 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2730 PF10805.3 EGO20197.1 - 0.011 15.5 1.6 0.073 12.8 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Tox-GHH PF15636.1 EGO20197.1 - 0.019 14.5 1.8 0.024 14.2 1.2 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin MscS_porin PF12795.2 EGO20197.1 - 0.029 13.7 1.9 0.035 13.4 1.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain WXG100 PF06013.7 EGO20197.1 - 0.069 13.1 2.3 3.1 7.8 0.2 2.4 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF4200 PF13863.1 EGO20197.1 - 0.074 12.9 14.8 0.22 11.4 10.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ERM PF00769.14 EGO20197.1 - 0.083 12.4 13.7 0.095 12.2 9.5 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Surfac_D-trimer PF09006.6 EGO20197.1 - 0.091 12.5 0.5 0.6 9.8 0.1 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Cytochrom_B562 PF07361.6 EGO20197.1 - 0.098 13.0 8.9 0.14 12.6 3.2 2.0 1 1 1 2 2 2 0 Cytochrome b562 Phlebovirus_NSM PF07246.6 EGO20197.1 - 0.1 11.7 5.7 0.15 11.2 3.7 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Peptidase_M15_2 PF05951.8 EGO20197.1 - 0.14 11.6 0.6 0.15 11.5 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) PKK PF12474.3 EGO20197.1 - 0.15 11.7 14.1 0.2 11.3 9.8 1.2 1 0 0 1 1 1 0 Polo kinase kinase HAUS-augmin3 PF14932.1 EGO20197.1 - 0.15 11.2 8.9 0.16 11.0 6.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CENP-Q PF13094.1 EGO20197.1 - 0.16 12.0 9.1 0.17 11.9 6.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4618 PF15397.1 EGO20197.1 - 0.17 11.1 10.2 2.1 7.6 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Spc7 PF08317.6 EGO20197.1 - 0.18 10.4 9.3 0.19 10.3 6.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Ax_dynein_light PF10211.4 EGO20197.1 - 0.31 10.8 10.5 0.35 10.6 7.3 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain Bacillus_HBL PF05791.6 EGO20197.1 - 0.54 9.6 5.4 1.7 7.9 2.2 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) THOC7 PF05615.8 EGO20197.1 - 0.55 10.5 7.9 0.63 10.3 5.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 bZIP_1 PF00170.16 EGO20197.1 - 0.58 10.1 8.4 5 7.1 0.7 2.7 1 1 1 2 2 2 0 bZIP transcription factor DUF4061 PF13270.1 EGO20197.1 - 0.67 10.0 5.9 1.2 9.2 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) CCDC84 PF14968.1 EGO20197.1 - 0.86 9.0 5.5 0.98 8.8 3.8 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DUF16 PF01519.11 EGO20197.1 - 0.87 9.8 8.1 0.99 9.6 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Pepsin-I3 PF06394.8 EGO20197.1 - 0.91 9.2 4.8 0.41 10.3 0.9 1.9 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain FlxA PF14282.1 EGO20197.1 - 0.95 9.4 7.2 0.76 9.7 4.1 1.4 1 1 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.17 EGO20197.1 - 1 9.4 8.6 17 5.5 6.0 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TACC PF05010.9 EGO20197.1 - 1.1 9.0 10.6 1.2 8.9 7.3 1.0 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Vps51 PF08700.6 EGO20197.1 - 1.1 9.1 5.3 8.8 6.2 0.6 2.4 1 1 0 2 2 2 0 Vps51/Vps67 OmpH PF03938.9 EGO20197.1 - 1.3 8.9 12.2 1.3 8.9 8.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YlqD PF11068.3 EGO20197.1 - 1.4 8.9 8.9 4.3 7.3 6.2 1.7 1 1 0 1 1 1 0 YlqD protein Prefoldin_2 PF01920.15 EGO20197.1 - 2 8.2 13.0 1.9 8.3 0.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit IncA PF04156.9 EGO20197.1 - 2.3 7.7 9.2 2.6 7.6 6.4 1.1 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 EGO20197.1 - 2.4 7.8 4.7 6.1 6.5 3.3 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 EGO20197.1 - 2.5 6.4 10.6 2.8 6.2 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.9 EGO20197.1 - 3.4 7.2 12.8 4 7.0 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GrpE PF01025.14 EGO20197.1 - 3.9 6.9 11.1 1.2e+02 2.1 7.7 2.0 1 1 0 1 1 1 0 GrpE APG6 PF04111.7 EGO20197.1 - 4.1 6.3 10.9 4.5 6.2 7.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC37_N PF03234.9 EGO20197.1 - 4.2 7.6 9.2 0.78 10.0 0.7 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding V-SNARE PF05008.10 EGO20197.1 - 6.1 7.0 9.7 3.7 7.7 2.5 2.0 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TMPIT PF07851.8 EGO20197.1 - 7 5.6 6.8 7.2 5.5 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2458 PF10454.4 EGO20197.1 - 7.4 6.4 9.6 8 6.3 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) HMG_box PF00505.14 EGO20198.1 - 2.9e-23 81.9 1.1 2.9e-23 81.9 0.8 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO20198.1 - 2.6e-17 62.9 1.1 2.6e-17 62.9 0.8 1.9 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.7 EGO20198.1 - 0.00082 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 EGO20198.1 - 0.039 13.7 0.1 0.039 13.7 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 YABBY PF04690.8 EGO20198.1 - 0.063 13.5 0.1 0.088 13.0 0.1 1.3 1 1 0 1 1 1 0 YABBY protein Flavi_capsid PF01003.14 EGO20198.1 - 0.076 12.5 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C DUF736 PF05284.7 EGO20198.1 - 0.084 12.7 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF736) ORC2 PF04084.9 EGO20199.1 - 1.6e-51 175.0 0.0 2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC2 PF04084.9 EGO20200.1 - 7.4e-12 44.7 0.0 8.3e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Phage_integrase PF00589.17 EGO20207.1 - 0.043 13.4 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Phage integrase family Amino_oxidase PF01593.19 EGO20208.1 - 1.8e-41 142.6 0.0 2.4e-40 138.9 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO20208.1 - 0.0004 20.3 0.0 0.0014 18.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain EF1G PF00647.14 EGO20209.1 - 5e-41 138.7 0.0 9.8e-41 137.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EGO20209.1 - 7.1e-11 42.1 0.0 1.9e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO20209.1 - 1.2e-07 31.6 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO20209.1 - 4.4e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO20209.1 - 5.9e-05 22.9 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO20209.1 - 6.3e-05 23.3 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO20209.1 - 0.00091 19.0 0.0 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.14 EGO20209.1 - 0.021 15.1 7.0 0.046 14.1 4.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abhydrolase_5 PF12695.2 EGO20209.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DNA_pol_E_B PF04042.11 EGO20211.1 - 0.067 12.4 0.1 0.084 12.1 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.20 EGO20213.1 - 9e-07 28.2 0.2 1e-05 24.8 0.1 2.1 1 1 1 2 2 2 1 Protein kinase domain Gam PF06064.6 EGO20213.1 - 0.27 11.3 2.4 30 4.8 0.1 3.1 2 1 1 3 3 3 0 Host-nuclease inhibitor protein Gam Nif11 PF07862.6 EGO20214.1 - 0.07 13.0 0.8 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function CHAT PF12770.2 EGO20215.1 - 5e-34 117.7 0.0 9.5e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EGO20215.1 - 4.9e-30 102.9 6.2 0.00049 19.6 0.0 10.1 4 2 7 11 11 11 8 TPR repeat TPR_12 PF13424.1 EGO20215.1 - 4.3e-24 84.2 10.5 0.0019 18.0 0.0 12.6 4 1 9 14 14 14 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGO20215.1 - 1.3e-15 56.4 18.9 1.3 9.9 0.0 12.9 9 3 5 14 14 14 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO20215.1 - 4.7e-13 48.1 14.1 0.052 13.1 0.0 11.6 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO20215.1 - 5.4e-13 47.7 0.0 1.2 9.0 0.0 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO20215.1 - 5.6e-12 44.6 11.3 0.18 11.8 0.0 11.1 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO20215.1 - 2.8e-09 36.4 6.3 0.021 14.9 0.0 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO20215.1 - 1.2e-07 32.1 7.5 1.4 9.6 0.0 7.5 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGO20215.1 - 3.7e-07 29.8 10.9 2.1 8.4 0.0 10.6 12 0 0 12 12 11 1 Tetratricopeptide repeat Sel1 PF08238.7 EGO20215.1 - 1.6e-05 25.3 0.0 24 5.7 0.0 7.7 9 0 0 9 9 8 0 Sel1 repeat DUF2379 PF09543.5 EGO20215.1 - 3.8e-05 23.6 0.4 0.89 9.5 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2379) TPR_7 PF13176.1 EGO20215.1 - 0.00016 21.2 5.8 2.5 8.1 0.0 8.5 11 0 0 11 11 10 1 Tetratricopeptide repeat Tn7_TnsC_Int PF11426.3 EGO20215.1 - 0.0038 16.9 3.8 13 5.6 0.0 5.9 7 0 0 7 7 6 0 Tn7 transposition regulator TnsC Glyoxalase_2 PF12681.2 EGO20215.1 - 0.021 15.4 0.0 2.2 8.9 0.0 3.6 3 0 0 3 3 3 0 Glyoxalase-like domain NAD_binding_10 PF13460.1 EGO20216.1 - 2.2e-28 99.5 0.0 2.6e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 EGO20216.1 - 0.00017 21.4 0.3 0.18 11.5 0.0 2.4 2 1 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGO20216.1 - 0.0018 18.5 0.1 0.0038 17.5 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.15 EGO20219.1 - 1.4e-22 79.8 0.0 1.4e-22 79.8 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGO20219.1 - 3.9e-17 63.3 0.0 8.9e-16 58.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO20219.1 - 3.3e-12 46.9 0.1 7.3e-12 45.8 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO20219.1 - 7.7e-06 25.7 0.0 4.9e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO20219.1 - 0.00018 21.1 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M16 PF00675.15 EGO20220.1 - 4.5e-23 81.6 0.0 7.7e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO20220.1 - 3.6e-08 33.2 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Methyltransf_23 PF13489.1 EGO20221.1 - 7.5e-12 45.2 0.5 1.3e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO20221.1 - 3.7e-10 40.1 0.0 6.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO20221.1 - 4.3e-10 39.3 0.0 1.5e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO20221.1 - 8.1e-07 29.4 0.1 5.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO20221.1 - 1e-06 28.0 0.0 3.7e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO20221.1 - 1.3e-06 28.7 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20221.1 - 2.6e-05 24.7 0.0 0.00026 21.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO20221.1 - 0.00022 21.2 0.1 0.0012 18.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO20221.1 - 0.00068 18.7 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EGO20221.1 - 0.00082 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EGO20221.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase BRCT PF00533.21 EGO20223.1 - 0.00017 21.6 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_pol_B_palm PF14792.1 EGO20224.1 - 5.1e-27 94.1 0.0 1.2e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EGO20224.1 - 4.5e-19 67.9 0.0 9e-19 66.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EGO20224.1 - 6.7e-17 60.7 0.1 8.5e-16 57.2 0.1 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EGO20224.1 - 3.1e-15 56.1 0.4 1.7e-14 53.7 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EGO20224.1 - 0.00038 20.5 0.1 0.83 9.8 0.0 2.8 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 EGO20224.1 - 0.019 14.6 0.1 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif NAD_binding_4 PF07993.7 EGO20225.1 - 2e-35 121.9 0.0 3e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO20225.1 - 6.3e-30 103.8 0.0 1.1e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGO20225.1 - 9.7e-09 34.9 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO20225.1 - 9.6e-07 28.9 0.0 6e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 NADH(P)-binding PP-binding PF00550.20 EGO20225.1 - 6e-05 23.2 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl-CoA_dh_C PF12806.2 EGO20232.1 - 0.076 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like KMP11 PF03037.11 EGO20234.1 - 0.11 13.1 0.3 0.2 12.2 0.2 1.4 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF2636 PF11120.3 EGO20234.1 - 0.11 11.9 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) ZZ PF00569.12 EGO20236.1 - 1e-17 63.3 36.9 1.2e-09 37.5 2.7 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type DUF2681 PF10883.3 EGO20237.1 - 0.04 14.1 1.6 1.5 9.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) UPF0227 PF05728.7 EGO20237.1 - 0.053 13.2 0.3 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) Med28 PF11594.3 EGO20237.1 - 0.066 13.4 1.6 0.15 12.3 0.6 2.0 1 1 1 2 2 2 0 Mediator complex subunit 28 TBPIP PF07106.8 EGO20237.1 - 0.099 12.1 3.1 0.34 10.4 0.2 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EGO20237.1 - 0.14 11.2 0.1 4.6 6.3 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 EGO20237.1 - 0.16 11.9 0.3 0.16 11.9 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) OGG_N PF07934.7 EGO20238.1 - 0.1 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Baculo_PEP_C PF04513.7 EGO20238.1 - 0.19 11.5 4.0 0.096 12.5 0.9 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 EGO20239.1 - 0.00037 20.2 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 Lipoprotein leucine-zipper AAA_13 PF13166.1 EGO20240.1 - 0.00068 18.2 2.0 0.0008 17.9 1.4 1.2 1 0 0 1 1 1 1 AAA domain Med4 PF10018.4 EGO20240.1 - 0.00085 18.7 4.5 0.0028 17.1 0.3 2.2 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Acyl-CoA_dh_C PF12806.2 EGO20240.1 - 0.005 16.7 1.3 0.0064 16.3 0.3 1.7 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Tektin PF03148.9 EGO20240.1 - 0.015 13.9 4.0 0.026 13.1 1.9 1.9 1 1 1 2 2 2 0 Tektin family Phlebovirus_NSM PF07246.6 EGO20240.1 - 0.029 13.5 0.2 0.044 12.9 0.1 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Transposase_22 PF02994.9 EGO20240.1 - 0.031 12.7 0.9 0.045 12.2 0.6 1.3 1 0 0 1 1 1 0 L1 transposable element Baculo_PEP_C PF04513.7 EGO20240.1 - 0.044 13.5 2.0 0.27 11.0 0.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_2 PF07716.10 EGO20240.1 - 0.11 12.3 1.1 0.28 11.0 0.3 2.1 1 1 1 2 2 2 0 Basic region leucine zipper GPW_gp25 PF04965.9 EGO20240.1 - 0.11 12.0 0.2 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Gene 25-like lysozyme Seryl_tRNA_N PF02403.17 EGO20240.1 - 0.15 12.0 8.3 3.3 7.7 2.6 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 EGO20240.1 - 0.29 11.0 4.5 0.78 9.6 3.1 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 EGO20240.1 - 0.33 10.4 7.2 1.6 8.2 1.1 3.0 3 0 0 3 3 3 0 Septum formation initiator Laminin_II PF06009.7 EGO20240.1 - 0.42 10.3 3.6 7.2 6.3 1.0 2.8 1 1 1 2 2 2 0 Laminin Domain II TBPIP PF07106.8 EGO20240.1 - 0.56 9.7 4.9 0.81 9.2 1.8 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 EGO20240.1 - 1.1 9.0 7.4 0.38 10.5 2.7 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2681 PF10883.3 EGO20240.1 - 2.4 8.4 5.8 1.6 8.9 0.3 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF2681) TMF_DNA_bd PF12329.3 EGO20240.1 - 4 7.3 10.0 0.26 11.1 2.1 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGO20240.1 - 4.7 6.7 12.5 2.4 7.7 4.2 2.8 1 1 2 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 EGO20241.1 - 0.00054 19.7 0.0 0.029 14.2 0.0 2.7 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Ax_dynein_light PF10211.4 EGO20241.1 - 0.0032 17.3 5.2 0.02 14.7 0.2 2.9 3 1 1 4 4 4 1 Axonemal dynein light chain Phage_lysis PF03245.8 EGO20241.1 - 0.046 13.7 3.7 0.39 10.6 0.3 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein TBPIP PF07106.8 EGO20241.1 - 0.053 13.0 4.8 0.18 11.3 0.1 3.2 3 2 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1469 PF07332.6 EGO20241.1 - 0.058 13.1 0.9 0.12 12.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF812 PF05667.6 EGO20241.1 - 0.12 10.8 7.2 0.022 13.2 0.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DivIC PF04977.10 EGO20241.1 - 0.14 11.6 5.6 3.1 7.3 1.6 2.8 2 0 0 2 2 2 0 Septum formation initiator Syntaxin PF00804.20 EGO20241.1 - 0.23 11.6 3.9 0.19 11.9 1.0 2.3 2 1 0 2 2 2 0 Syntaxin CDC37_N PF03234.9 EGO20241.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.4 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding HrpB7 PF09486.5 EGO20241.1 - 0.71 9.7 6.8 19 5.1 0.2 3.3 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Tropomyosin_1 PF12718.2 EGO20241.1 - 1.1 9.0 11.0 0.96 9.2 0.0 3.1 3 1 0 3 3 3 0 Tropomyosin like DUF4618 PF15397.1 EGO20241.1 - 2.4 7.4 10.0 1 8.6 2.3 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) Seryl_tRNA_N PF02403.17 EGO20241.1 - 5.8 6.9 13.2 0.65 10.0 2.0 3.6 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Retrotrans_gag PF03732.12 EGO20242.1 - 2.8e-05 24.1 0.0 6.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20242.1 - 0.00014 21.6 3.9 0.00034 20.4 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGO20242.1 - 0.049 13.1 0.4 0.11 11.9 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2477 PF10631.4 EGO20242.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2477) HET PF06985.6 EGO20248.1 - 4.2e-18 65.8 7.8 1.1e-15 58.0 0.4 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) PRP8_domainIV PF12134.3 EGO20250.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 PRP8 domain IV core adh_short PF00106.20 EGO20251.1 - 8.2e-21 74.6 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO20251.1 - 1.3e-13 51.2 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO20251.1 - 2.8e-06 27.1 0.0 5.8e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO20251.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO20251.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGO20251.1 - 0.1 12.3 0.1 0.62 9.8 0.0 2.4 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4147 PF13660.1 EGO20252.1 - 0.014 14.5 0.1 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Fanconi_A PF03511.9 EGO20252.1 - 0.074 12.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Fanconi anaemia group A protein GATA PF00320.22 EGO20256.1 - 5e-26 89.7 19.9 1.4e-15 56.3 2.4 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EGO20256.1 - 3.6e-11 42.4 0.6 6.8e-11 41.5 0.4 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 EGO20256.1 - 0.16 11.3 6.7 0.15 11.4 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 EGO20256.1 - 1.9 8.1 8.4 4.8 6.8 0.5 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RRN7 PF11781.3 EGO20256.1 - 3.4 7.2 9.8 0.3 10.6 0.4 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 EGO20256.1 - 4.5 6.9 7.1 2.6 7.6 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 EGO20256.1 - 5.2 6.8 5.3 14 5.4 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 EGO20256.1 - 7 6.4 8.0 2.4 7.9 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EGO20256.1 - 7.1 6.5 10.6 74 3.2 0.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_c3_2 PF14537.1 EGO20256.1 - 7.7 6.9 9.1 77 3.7 6.1 2.4 1 1 1 2 2 2 0 Cytochrome c3 zf-RING_3 PF14369.1 EGO20256.1 - 8.3 6.5 7.5 0.38 10.7 0.6 2.2 2 0 0 2 2 2 0 zinc-finger Zn-ribbon_8 PF09723.5 EGO20256.1 - 9 6.3 10.5 7.2 6.6 0.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain AMP-binding PF00501.23 EGO20257.1 - 8.4e-84 281.3 0.0 1.2e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO20257.1 - 0.013 16.3 0.1 0.07 14.0 0.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.1 EGO20258.1 - 7.1e-10 39.3 0.3 1.4e-09 38.3 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO20258.1 - 5.4e-05 23.1 0.6 0.0016 18.3 0.4 2.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.23 EGO20260.1 - 2.9e-05 22.6 0.0 3.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO20261.1 - 7.3e-30 103.7 0.0 1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO20261.1 - 5.2e-11 42.4 0.0 9.3e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO20261.1 - 5.2e-05 23.2 0.2 0.00041 20.2 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO20261.1 - 0.00038 19.2 0.0 0.00068 18.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EGO20261.1 - 0.00051 20.2 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EGO20261.1 - 0.0015 18.2 0.2 0.01 15.4 0.1 2.2 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGO20261.1 - 0.036 12.9 0.0 0.095 11.5 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ACPS PF01648.15 EGO20262.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily AA_permease_2 PF13520.1 EGO20263.1 - 1.2e-42 145.9 61.0 1.5e-42 145.6 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO20263.1 - 5.7e-20 71.1 54.7 7.6e-20 70.7 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 EGO20263.1 - 1.9 7.4 7.3 0.073 12.0 0.3 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 zf-MYND PF01753.13 EGO20264.1 - 7.7e-11 41.6 13.9 1.6e-10 40.7 9.5 1.7 1 1 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EGO20264.1 - 0.077 12.2 6.9 0.36 10.1 4.8 2.1 1 1 0 1 1 1 0 Life-span regulatory factor zinc-ribbons_6 PF07191.7 EGO20264.1 - 0.28 11.0 6.9 0.47 10.2 4.8 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-HIT PF04438.11 EGO20264.1 - 1.7 8.3 14.7 5.6 6.7 10.2 1.9 1 1 0 1 1 1 0 HIT zinc finger ABM PF03992.11 EGO20266.1 - 0.0019 18.1 0.1 1.6 8.8 0.1 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase ACOX PF01756.14 EGO20267.1 - 1.8e-31 108.9 0.0 2.8e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGO20267.1 - 1.2e-08 34.2 1.6 4.1e-07 29.4 0.1 2.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGO20267.1 - 0.00093 19.3 0.0 0.0027 17.8 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EGO20267.1 - 0.093 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal La PF05383.12 EGO20269.1 - 1.7e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EGO20269.1 - 1.7e-05 24.3 0.1 2.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO20269.1 - 0.00029 20.7 0.1 0.00048 20.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EGO20270.1 - 0.32 8.8 1.1 0.32 8.7 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.10 EGO20270.1 - 0.44 10.5 17.1 0.73 9.8 11.9 1.2 1 0 0 1 1 1 0 Fez1 DUF3329 PF11808.3 EGO20271.1 - 0.084 12.9 0.1 0.087 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) PepSY_TM_1 PF13172.1 EGO20271.1 - 1.8 8.4 5.5 1.8 8.3 3.0 1.7 1 1 0 1 1 1 0 PepSY-associated TM helix STE3 PF02076.10 EGO20273.1 - 8.9e-71 238.2 19.1 1e-70 238.0 13.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor WD40 PF00400.27 EGO20274.1 - 3.2e-62 204.3 26.8 2.1e-12 46.3 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat NACHT PF05729.7 EGO20274.1 - 9.6e-07 28.6 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO20274.1 - 5.9e-06 26.3 0.1 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 EGO20274.1 - 0.00054 19.5 5.1 15 5.3 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EGO20274.1 - 0.00082 17.6 4.9 2.4 6.1 1.8 4.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA_22 PF13401.1 EGO20274.1 - 0.0027 17.8 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EGO20274.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 EGO20274.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EGO20274.1 - 0.087 13.0 0.1 0.58 10.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGO20274.1 - 0.11 12.6 0.1 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EGO20274.1 - 0.24 10.4 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TP6A_N PF04406.9 EGO20276.1 - 0.064 12.9 0.0 5.3 6.7 0.0 2.7 3 0 0 3 3 3 0 Type IIB DNA topoisomerase Peptidase_S9 PF00326.16 EGO20277.1 - 5.3e-29 100.9 0.0 8.3e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO20277.1 - 9.1e-07 28.7 0.2 1.7e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO20277.1 - 5.1e-06 26.5 3.0 1.7e-05 24.8 2.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO20277.1 - 0.00026 20.6 0.2 0.0012 18.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO20277.1 - 0.0025 17.3 0.1 0.0096 15.5 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EGO20277.1 - 0.025 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.8 EGO20277.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Aconitase PF00330.15 EGO20278.1 - 2.7e-176 586.6 0.1 4e-176 586.0 0.1 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO20278.1 - 1.8e-46 157.4 0.0 3.2e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Xpo1 PF08389.7 EGO20279.1 - 5.2e-08 32.9 2.8 5.1e-06 26.4 0.0 4.2 4 2 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EGO20279.1 - 0.00034 20.4 0.5 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.6 EGO20279.1 - 0.26 10.1 0.0 0.76 8.6 0.0 1.8 2 0 0 2 2 2 0 CRM1 C terminal Tyr-DNA_phospho PF06087.7 EGO20282.1 - 1.3e-49 169.1 0.0 6.2e-49 166.8 0.0 1.9 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EGO20282.1 - 0.0017 18.0 0.0 1.8 8.3 0.1 2.6 2 1 0 2 2 2 2 PLD-like domain SNF5 PF04855.7 EGO20282.1 - 0.013 15.0 0.6 0.02 14.3 0.4 1.3 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 UIM PF02809.15 EGO20282.1 - 0.7 9.6 10.5 0.35 10.5 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Glyoxalase_2 PF12681.2 EGO20285.1 - 0.14 12.7 0.0 0.37 11.4 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain HTH_33 PF13592.1 EGO20286.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Sugar_tr PF00083.19 EGO20287.1 - 1e-87 294.6 28.1 1.2e-87 294.4 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO20287.1 - 1.5e-19 69.9 39.2 1.2e-15 57.0 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B_2 PF12706.2 EGO20288.1 - 2.5e-31 108.7 0.1 3.2e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO20288.1 - 1.2e-09 38.1 0.0 2.6e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO20288.1 - 0.072 12.7 4.9 0.39 10.3 1.4 2.7 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily DNA_pol_B_exo2 PF10108.4 EGO20289.1 - 0.022 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB adh_short PF00106.20 EGO20290.1 - 2.2e-20 73.2 0.0 3.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20290.1 - 6.2e-09 35.7 0.0 9.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO20290.1 - 0.00037 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGO20290.1 - 0.00051 19.5 0.1 0.00097 18.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO20290.1 - 0.021 14.8 0.1 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Alpha_kinase PF02816.13 EGO20291.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 EGO20298.1 - 1.6e-22 78.5 9.3 4.1e-11 42.3 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1283 PF06932.6 EGO20299.1 - 0.025 14.6 3.6 0.025 14.6 2.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1283) CDC45 PF02724.9 EGO20299.1 - 1.8 6.4 12.1 2.1 6.2 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 EGO20299.1 - 6.9 4.9 6.7 8.7 4.6 4.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sugar_tr PF00083.19 EGO20301.1 - 1.4e-85 287.6 17.9 1.6e-85 287.4 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO20301.1 - 6.7e-30 103.9 26.2 2.9e-17 62.4 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGO20301.1 - 0.049 13.6 10.0 0.87 9.6 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Rick_17kDa_Anti PF05433.10 EGO20301.1 - 0.21 11.2 5.2 0.72 9.5 3.6 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain ABC2_membrane_5 PF13346.1 EGO20301.1 - 4.4 6.5 7.0 0.83 8.8 0.0 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein Sugar_tr PF00083.19 EGO20303.1 - 9.4e-82 274.9 18.8 1.1e-81 274.7 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO20303.1 - 1.6e-20 73.1 34.0 1.1e-10 40.7 11.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Cytochrome-c551 PF10643.4 EGO20303.1 - 0.06 12.6 0.1 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF1228 PF06779.9 EGO20303.1 - 0.067 13.2 0.4 0.067 13.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) ABC2_membrane_5 PF13346.1 EGO20303.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.2 3 1 0 3 3 3 0 ABC-2 family transporter protein Sugar_tr PF00083.19 EGO20304.1 - 2.1e-89 300.1 26.7 2.5e-89 299.9 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO20304.1 - 7.8e-19 67.5 42.7 3.8e-14 52.1 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_38 PF01074.17 EGO20307.1 - 3.5e-81 272.4 0.2 5.1e-81 271.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGO20307.1 - 5.1e-63 213.4 0.0 7.4e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGO20307.1 - 4.5e-25 87.6 0.0 9.8e-25 86.5 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 EGO20307.1 - 0.0035 16.3 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 zf-ribbon_3 PF13248.1 EGO20308.1 - 1.5 8.1 4.4 18 4.7 0.1 3.2 2 1 2 4 4 4 0 zinc-ribbon domain GPI-anchored PF10342.4 EGO20309.1 - 0.00097 19.5 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dynamin_M PF01031.15 EGO20310.1 - 7.1e-31 107.0 0.0 1.5e-21 76.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EGO20310.1 - 7.6e-21 74.6 0.0 3.4e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EGO20310.1 - 4.9e-10 39.1 0.1 1.5e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO20310.1 - 0.032 14.1 0.1 0.62 10.0 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase WD40 PF00400.27 EGO20311.1 - 1.3e-08 34.4 5.2 0.0033 17.2 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Ribosomal_L14 PF00238.14 EGO20312.1 - 1.1e-33 115.5 0.0 1.3e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNB PF00773.14 EGO20313.1 - 1.1e-91 307.5 0.0 1.6e-91 306.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EGO20313.1 - 3.4e-09 36.8 0.0 9.7e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 EGO20313.1 - 0.21 11.0 3.9 0.2 11.2 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Beta-TrCP_D PF12125.3 EGO20314.1 - 2.1 7.9 4.2 1.9 8.1 0.4 2.6 3 0 0 3 3 3 0 D domain of beta-TrCP HAMP PF00672.20 EGO20315.1 - 0.1 12.7 0.6 2.2 8.5 0.4 2.5 2 0 0 2 2 2 0 HAMP domain His_Phos_2 PF00328.17 EGO20316.1 - 7.3e-18 65.0 0.0 9.7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 EGO20317.1 - 6.2e-26 90.9 24.7 8.5e-26 90.4 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_10 PF05971.7 EGO20320.1 - 6.4e-54 183.1 0.2 7.4e-54 182.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EGO20320.1 - 2.6e-05 24.2 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO20320.1 - 0.00084 18.7 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGO20320.1 - 0.00098 18.3 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGO20320.1 - 0.0033 17.9 0.0 0.0048 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF633 PF04816.7 EGO20320.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) Met_10 PF02475.11 EGO20320.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 EGO20320.1 - 0.057 13.0 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UCR_hinge PF02320.11 EGO20321.1 - 1.2e-17 63.5 3.9 1.2e-17 63.5 2.7 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein JSRP PF15312.1 EGO20321.1 - 0.1 12.6 1.0 5.4 7.0 0.6 2.3 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein YqfQ PF14181.1 EGO20321.1 - 0.26 11.3 1.8 0.29 11.1 1.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein LELP1 PF15042.1 EGO20321.1 - 0.32 11.1 5.6 2.2 8.4 3.9 2.0 1 1 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 DUF4652 PF15525.1 EGO20321.1 - 0.76 9.1 2.8 0.94 8.8 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) DNA_pol_phi PF04931.8 EGO20321.1 - 8.3 4.0 7.1 8.7 3.9 4.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi F-box-like PF12937.2 EGO20322.1 - 0.0095 15.6 2.0 0.0095 15.6 1.4 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EGO20322.1 - 0.39 10.4 6.2 0.11 12.2 1.5 2.2 2 0 0 2 2 2 0 F-box domain Acyl-CoA_dh_M PF02770.14 EGO20323.1 - 3.9e-05 23.0 0.0 7.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain zf-CCHC PF00098.18 EGO20324.1 - 0.00053 19.7 2.3 0.0011 18.8 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EGO20325.1 - 9.7e-08 31.7 0.0 2.3e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO20325.1 - 0.00023 21.5 0.0 0.00023 21.5 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO20325.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease UBN2_2 PF14227.1 EGO20326.1 - 1.6e-08 34.1 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO20326.1 - 6.5e-05 22.6 0.0 8.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RE_HaeIII PF09556.5 EGO20326.1 - 0.026 13.4 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease DUF4219 PF13961.1 EGO20327.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EGO20327.1 - 0.054 13.0 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AAA_11 PF13086.1 EGO20329.1 - 7.8e-10 38.7 0.0 3.5e-08 33.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO20329.1 - 9.5e-09 34.8 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO20329.1 - 1.2e-06 28.2 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EGO20329.1 - 0.00081 19.0 0.0 0.00082 19.0 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_33 PF13671.1 EGO20329.1 - 0.0044 16.9 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Wax2_C PF12076.3 EGO20329.1 - 0.005 16.5 0.1 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 WAX2 C-terminal domain AAA_16 PF13191.1 EGO20329.1 - 0.0059 16.6 0.1 0.02 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EGO20329.1 - 0.025 14.8 0.0 0.047 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGO20329.1 - 0.026 14.7 1.0 0.029 14.5 0.7 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO20329.1 - 0.034 14.2 0.1 0.046 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGO20329.1 - 0.036 13.6 0.5 0.031 13.8 0.4 1.2 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EGO20329.1 - 0.051 12.9 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase MobB PF03205.9 EGO20329.1 - 0.065 12.9 0.1 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EGO20329.1 - 0.067 12.6 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EGO20329.1 - 0.091 11.6 0.2 0.25 10.1 0.2 1.7 1 1 1 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 EGO20329.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EGO20329.1 - 0.12 11.1 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 EGO20329.1 - 0.52 11.1 7.2 6.2 7.6 5.0 2.1 1 1 0 1 1 1 0 AAA domain OPT PF03169.10 EGO20331.1 - 1.8e-85 287.6 39.0 2.4e-85 287.2 27.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dynamin_M PF01031.15 EGO20332.1 - 1.9e-26 92.5 0.0 5.9e-18 64.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EGO20332.1 - 1.3e-23 83.6 0.0 2.9e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGO20332.1 - 1.1e-09 38.0 0.4 4.9e-09 35.9 0.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO20332.1 - 0.00017 21.5 0.0 0.0028 17.6 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO20332.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PMSR PF01625.16 EGO20333.1 - 1.3e-55 187.5 0.7 2e-55 186.9 0.5 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CsbD PF05532.7 EGO20335.1 - 0.031 13.9 0.6 0.062 12.9 0.4 1.4 1 0 0 1 1 1 0 CsbD-like Amidohydro_4 PF13147.1 EGO20336.1 - 4.2e-30 105.7 0.0 5.5e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGO20336.1 - 2.3e-14 53.7 0.7 6.4e-06 26.0 0.7 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO20336.1 - 9e-14 51.0 3.0 9e-14 51.0 2.1 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO20336.1 - 2.3e-08 33.6 0.1 0.00037 19.8 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EGO20336.1 - 0.04 14.0 0.8 0.12 12.5 0.5 1.8 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain DUF350 PF03994.9 EGO20338.1 - 0.12 12.1 1.3 0.18 11.5 0.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) gag-asp_proteas PF13975.1 EGO20339.1 - 6.4e-11 41.9 0.0 9.1e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO20339.1 - 5.4e-08 32.8 0.0 5.9e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO20339.1 - 5.5e-06 26.7 0.0 7.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease PLDc_3 PF13918.1 EGO20340.1 - 0.054 12.9 0.0 0.058 12.8 0.0 1.0 1 0 0 1 1 1 0 PLD-like domain Rap_GAP PF02145.10 EGO20341.1 - 8.8e-50 168.6 0.0 1.3e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Glyco_hydro_3 PF00933.16 EGO20343.1 - 7e-68 228.7 0.2 9.9e-68 228.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain RRM_1 PF00076.17 EGO20344.1 - 6.3e-38 128.2 0.2 2.5e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO20344.1 - 1.2e-34 118.0 0.1 2.7e-17 62.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO20344.1 - 8.3e-15 54.3 0.0 3.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGO20344.1 - 6.3e-05 22.4 0.3 0.026 14.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EGO20344.1 - 0.00013 21.7 0.0 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGO20344.1 - 0.0032 17.2 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif COG7 PF10191.4 EGO20345.1 - 6.1e-86 289.0 11.6 1e-49 169.2 3.8 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) LIM PF00412.17 EGO20346.1 - 9.5e-17 60.8 14.9 1.5e-13 50.5 5.1 2.4 2 0 0 2 2 2 2 LIM domain UPF0547 PF10571.4 EGO20346.1 - 0.1 12.3 9.0 0.23 11.2 0.1 3.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2082 PF09855.4 EGO20346.1 - 0.26 11.1 3.5 1.4 8.8 0.9 2.9 2 1 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-ribbon_3 PF13248.1 EGO20346.1 - 0.31 10.2 17.3 0.32 10.2 0.6 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DUF329 PF03884.9 EGO20346.1 - 1.2 8.7 11.2 10 5.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF329) DUF3039 PF11238.3 EGO20346.1 - 2.1 7.8 7.6 6 6.3 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3039) zinc_ribbon_2 PF13240.1 EGO20346.1 - 2.9 7.4 12.6 5.3 6.6 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EGO20346.1 - 3.3 7.6 23.4 0.6 9.9 4.8 3.1 2 1 0 3 3 3 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 EGO20346.1 - 4.3 7.6 12.7 1.5 9.1 2.5 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-DNA_Pol PF08996.5 EGO20346.1 - 4.6 6.5 8.0 0.12 11.7 0.9 1.7 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger HEAT_2 PF13646.1 EGO20347.1 - 1.3e-12 47.8 9.1 0.015 15.5 0.0 9.6 8 2 3 11 11 11 5 HEAT repeats HEAT PF02985.17 EGO20347.1 - 1.1e-11 43.7 6.8 0.33 11.1 0.0 10.3 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EGO20347.1 - 5.6e-06 26.6 12.6 0.03 14.8 0.1 8.4 6 1 2 8 8 8 1 HEAT-like repeat Arm PF00514.18 EGO20347.1 - 9.4e-05 22.0 3.1 0.0054 16.5 0.1 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Syja_N PF02383.13 EGO20348.1 - 1.9e-85 286.4 0.0 3.2e-85 285.6 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Chromo PF00385.19 EGO20350.1 - 3.3e-05 23.4 0.1 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rft-1 PF04506.8 EGO20352.1 - 1.1e-88 297.9 9.1 2.1e-88 297.0 6.3 1.4 1 1 0 1 1 1 1 Rft protein SAP PF02037.22 EGO20353.1 - 1.4e-05 24.4 0.7 2.2e-05 23.8 0.5 1.3 1 0 0 1 1 1 1 SAP domain AAA_12 PF13087.1 EGO20355.1 - 1.6e-57 194.0 0.0 2.2e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO20355.1 - 2.8e-24 86.0 0.6 5.2e-24 85.1 0.4 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGO20355.1 - 8.2e-05 22.2 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGO20355.1 - 0.021 14.3 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1152 PF06626.7 EGO20357.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) zf-RanBP PF00641.13 EGO20358.1 - 0.013 14.5 15.6 0.2 10.8 2.5 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Apc1 PF12859.2 EGO20359.1 - 9.2e-08 32.2 0.3 6.8e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EGO20359.1 - 0.45 10.8 0.0 0.45 10.8 0.0 5.5 7 0 0 7 7 7 0 Proteasome/cyclosome repeat DAHP_synth_1 PF00793.15 EGO20360.1 - 9.2e-95 316.4 0.0 1.1e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PIH1 PF08190.7 EGO20361.1 - 1.7e-28 100.0 0.1 1.8e-27 96.6 0.1 2.3 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Peptidase_C65 PF10275.4 EGO20362.1 - 5e-62 209.4 0.0 5.9e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EGO20362.1 - 3.2e-06 27.7 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 2 OTU-like cysteine protease TPR_10 PF13374.1 EGO20363.1 - 1e-96 314.4 13.6 2e-11 43.4 0.0 9.0 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 EGO20363.1 - 1.1e-93 307.2 27.3 1.7e-20 72.7 1.6 6.3 2 2 2 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 EGO20363.1 - 4.7e-44 146.2 34.3 2.5e-06 26.8 0.0 9.2 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 EGO20363.1 - 5.7e-42 138.2 22.9 1.5e-05 24.3 0.1 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EGO20363.1 - 1.4e-37 124.5 26.7 3.5e-05 23.3 0.0 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 EGO20363.1 - 1.3e-35 120.8 15.0 1.3e-08 34.3 0.0 5.3 4 1 0 5 5 5 5 TPR repeat TPR_8 PF13181.1 EGO20363.1 - 7.6e-25 84.7 28.5 0.00017 21.1 0.0 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGO20363.1 - 3.6e-22 78.4 13.5 6.1e-07 29.9 0.9 5.7 4 3 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO20363.1 - 4.4e-22 76.3 10.5 0.9 9.9 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.1 EGO20363.1 - 1.5e-21 74.9 15.8 0.035 14.7 0.0 8.7 5 3 4 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGO20363.1 - 7.9e-18 64.5 16.5 0.00027 21.2 0.1 6.6 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.9 EGO20363.1 - 2e-17 61.7 0.0 0.0061 16.8 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO20363.1 - 1.3e-15 57.2 16.5 0.00065 19.7 0.0 5.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGO20363.1 - 3.2e-12 46.0 24.4 0.56 10.7 0.1 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat PPR PF01535.15 EGO20363.1 - 5.4e-11 41.7 9.4 0.11 12.5 0.0 7.9 9 0 0 9 9 9 3 PPR repeat TPR_3 PF07720.7 EGO20363.1 - 2.3e-07 30.4 22.7 0.17 11.7 0.1 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat 14-3-3 PF00244.15 EGO20363.1 - 5.3e-06 25.6 0.0 0.83 8.6 0.2 4.6 2 2 4 6 6 6 1 14-3-3 protein Tcf25 PF04910.9 EGO20363.1 - 1.1e-05 24.5 5.3 2.5 6.9 0.0 6.2 1 1 5 7 7 7 1 Transcriptional repressor TCF25 Coatomer_E PF04733.9 EGO20363.1 - 1.9e-05 24.0 5.1 0.59 9.2 0.0 6.1 1 1 7 8 8 8 1 Coatomer epsilon subunit DUF3366 PF11846.3 EGO20363.1 - 0.00038 20.3 9.8 0.26 11.1 0.0 5.8 1 1 4 5 5 5 1 Domain of unknown function (DUF3366) Rab5-bind PF09311.6 EGO20363.1 - 0.005 16.7 0.1 42 3.9 0.0 4.4 3 2 3 6 6 5 0 Rabaptin-like protein TPR_5 PF12688.2 EGO20363.1 - 0.0057 16.6 11.9 0.29 11.1 0.4 5.5 4 2 2 6 6 6 1 Tetratrico peptide repeat AP2 PF00847.15 EGO20363.1 - 0.056 13.6 1.0 12 6.1 0.1 3.8 4 0 0 4 4 3 0 AP2 domain Mad3_BUB1_I PF08311.7 EGO20363.1 - 6.7 6.5 7.7 80 3.0 0.0 4.8 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 zf-CCHC PF00098.18 EGO20364.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO20364.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO20364.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Zn_Tnp_IS91 PF14319.1 EGO20366.1 - 0.0078 15.7 0.6 0.0094 15.4 0.4 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-C4pol PF14260.1 EGO20366.1 - 0.055 13.4 1.2 0.081 12.9 0.9 1.3 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EGO20366.1 - 0.055 13.2 6.0 0.13 12.1 4.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGO20366.1 - 0.072 12.3 6.4 0.79 9.0 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_3 PF13917.1 EGO20366.1 - 0.23 11.2 4.1 0.37 10.5 2.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_2 PF13240.1 EGO20366.1 - 3.8 7.1 7.6 1 8.9 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.19 EGO20366.1 - 5.5 6.9 8.7 27 4.7 6.0 2.1 1 1 0 1 1 1 0 B-box zinc finger Beta-lactamase PF00144.19 EGO20369.1 - 1.5e-42 145.8 0.2 2e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.19 EGO20370.1 - 6e-36 124.1 0.0 9.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Bromo_TP PF07524.8 EGO20371.1 - 8.5e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EGO20371.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF159 PF02586.9 EGO20372.1 - 7.9e-51 172.5 0.1 1e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Troponin-I_N PF11636.3 EGO20372.1 - 0.086 12.5 3.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Troponin I residues 1-32 AMP-binding PF00501.23 EGO20373.1 - 1.7e-16 59.6 0.0 2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 EGO20373.1 - 0.14 10.6 0.1 0.21 10.0 0.1 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter NAD_binding_4 PF07993.7 EGO20374.1 - 2.4e-31 108.5 0.0 3.4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO20374.1 - 1e-11 43.8 0.1 1.4e-10 40.1 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGO20374.1 - 9.5e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO20374.1 - 0.0011 18.8 0.1 0.014 15.2 0.1 2.7 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO20374.1 - 0.0073 15.0 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EGO20374.1 - 0.0077 16.4 0.0 0.038 14.2 0.0 2.2 2 1 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.5 EGO20374.1 - 0.019 14.6 0.1 0.077 12.6 0.1 2.0 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EGO20374.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.23 EGO20375.1 - 7.8e-31 106.8 0.0 9.8e-29 99.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO20375.1 - 3.9e-30 104.5 0.0 5.6e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO20375.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO20375.1 - 0.0059 16.5 0.0 0.051 13.4 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EGO20375.1 - 0.013 15.7 0.0 0.052 13.8 0.0 2.1 2 1 0 2 2 2 0 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EGO20375.1 - 0.026 13.2 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EGO20375.1 - 0.037 14.3 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EGO20375.1 - 0.063 12.9 0.1 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 KR domain Amidohydro_3 PF07969.6 EGO20377.1 - 4.3e-54 184.2 0.0 5.5e-33 114.7 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EGO20377.1 - 1.2e-08 34.9 0.0 5.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGO20377.1 - 6.3e-06 26.4 0.4 0.016 15.2 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGO20377.1 - 0.00017 21.3 0.0 0.00048 19.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase TFIIE_beta PF02186.10 EGO20378.1 - 0.0017 18.3 0.5 0.0035 17.3 0.1 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain Methyltransf_31 PF13847.1 EGO20378.1 - 0.064 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EGO20379.1 - 0.00017 20.8 0.1 0.00036 19.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO20379.1 - 0.00046 19.3 0.1 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF957 PF06117.6 EGO20381.1 - 0.025 14.1 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) LSM PF01423.17 EGO20383.1 - 4.2e-12 45.4 0.0 4.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.1 EGO20384.1 - 8.8e-21 73.7 8.9 3.4e-09 36.8 0.0 9.7 9 1 1 10 10 10 3 HEAT-like repeat HEAT PF02985.17 EGO20384.1 - 3.7e-18 63.9 15.1 0.00022 21.0 0.0 11.4 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 EGO20384.1 - 9.3e-18 64.2 6.2 1.8e-05 24.9 0.0 8.1 2 1 6 8 8 8 6 HEAT repeats IBN_N PF03810.14 EGO20384.1 - 2.8e-12 46.3 0.7 2.3e-11 43.4 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EGO20384.1 - 2.5e-07 30.2 9.9 0.0031 17.2 0.0 5.9 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGO20384.1 - 3.5e-05 22.3 1.0 0.051 11.9 0.0 3.5 2 2 0 2 2 2 2 Adaptin N terminal region DUF3385 PF11865.3 EGO20384.1 - 0.0021 18.0 0.8 2.9 7.8 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.3 EGO20384.1 - 0.0026 17.1 0.2 9.9 5.4 0.0 4.6 2 2 3 5 5 5 1 CLASP N terminal Lon_C PF05362.8 EGO20385.1 - 1.5e-66 223.6 0.4 2.4e-66 222.9 0.3 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGO20385.1 - 1.2e-21 77.2 0.0 3.6e-21 75.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO20385.1 - 4.3e-11 42.6 0.0 9.6e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON PF02190.11 EGO20385.1 - 1e-09 38.4 0.0 2.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EGO20385.1 - 1.1e-07 31.4 0.3 7.3e-07 28.7 0.0 2.4 2 1 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EGO20385.1 - 1.1e-05 25.3 0.0 6.1e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGO20385.1 - 0.00012 22.8 0.0 0.00057 20.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO20385.1 - 0.00069 19.6 3.0 0.00088 19.3 0.1 2.7 3 1 0 3 3 1 1 AAA ATPase domain AAA_33 PF13671.1 EGO20385.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO20385.1 - 0.0027 16.8 0.0 0.048 12.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGO20385.1 - 0.0027 17.8 0.6 0.048 13.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO20385.1 - 0.004 16.8 0.5 0.028 14.1 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_3 PF07726.6 EGO20385.1 - 0.0081 15.7 0.0 0.027 14.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGO20385.1 - 0.01 16.1 0.1 0.062 13.6 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.1 EGO20385.1 - 0.01 15.2 0.1 0.037 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EGO20385.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 EGO20385.1 - 0.024 14.4 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase TIP49 PF06068.8 EGO20385.1 - 0.027 13.2 0.0 0.067 11.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus IstB_IS21 PF01695.12 EGO20385.1 - 0.041 13.2 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 EGO20385.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EGO20385.1 - 0.074 12.1 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGO20385.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGO20385.1 - 0.11 12.0 0.7 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGO20385.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase adh_short PF00106.20 EGO20387.1 - 7.2e-22 78.0 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20387.1 - 8.1e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO20387.1 - 8.1e-06 25.9 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EGO20387.1 - 0.00096 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EGO20387.1 - 0.0074 16.3 0.0 0.016 15.3 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EGO20387.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HALZ PF02183.13 EGO20388.1 - 0.014 15.0 0.4 0.046 13.4 0.3 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4423 PF14394.1 EGO20388.1 - 0.055 13.0 2.1 0.089 12.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Mnd1 PF03962.10 EGO20388.1 - 0.066 12.8 9.2 0.11 12.1 6.4 1.3 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 EGO20388.1 - 0.071 13.0 9.2 0.11 12.3 6.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 EGO20388.1 - 0.093 11.1 2.9 0.13 10.6 2.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1192 PF06698.6 EGO20388.1 - 0.12 12.2 3.2 0.14 11.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) AAA_13 PF13166.1 EGO20388.1 - 0.13 10.6 6.2 0.18 10.2 4.3 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EGO20388.1 - 0.14 11.2 11.5 0.2 10.6 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2680 PF10925.3 EGO20388.1 - 0.15 11.9 2.2 0.34 10.8 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) PulG PF11773.3 EGO20388.1 - 0.16 11.7 1.1 0.29 10.8 0.7 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin DUF2968 PF11180.3 EGO20388.1 - 0.25 10.6 9.5 0.42 9.9 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 EGO20388.1 - 0.29 9.7 9.8 0.42 9.2 6.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cluap1 PF10234.4 EGO20388.1 - 0.47 9.6 12.4 0.65 9.1 8.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 IncA PF04156.9 EGO20388.1 - 0.48 9.9 13.4 0.75 9.3 9.3 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EGO20388.1 - 0.66 8.3 5.0 0.9 7.8 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EGO20388.1 - 0.7 8.7 8.3 1.2 8.0 5.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 EGO20388.1 - 0.94 8.9 12.8 0.73 9.2 1.8 2.3 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF869 PF05911.6 EGO20388.1 - 1.2 7.3 13.1 1.7 6.7 9.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) zf-C4H2 PF10146.4 EGO20388.1 - 1.5 8.7 8.4 2.5 8.0 5.8 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF16 PF01519.11 EGO20388.1 - 1.8 8.8 8.1 3.2 8.0 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF972 PF06156.8 EGO20388.1 - 7.1 7.0 8.7 3.5 8.0 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) zf-CCHC_3 PF13917.1 EGO20393.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO20393.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO20393.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger FliS PF02561.9 EGO20394.1 - 0.0053 16.5 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Flagellar protein FliS Choline_kinase PF01633.15 EGO20396.1 - 3.9e-48 163.8 0.0 5.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGO20396.1 - 1.7e-13 50.9 0.0 2.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGO20396.1 - 0.049 12.7 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ldh_1_C PF02866.13 EGO20398.1 - 2.1e-38 131.7 0.1 2.8e-38 131.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGO20398.1 - 3e-34 117.8 0.3 6.8e-34 116.7 0.2 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGO20398.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CholecysA-Rec_N PF09193.5 EGO20400.1 - 0.11 12.4 0.4 0.35 10.7 0.2 1.9 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal DUF2348 PF09807.4 EGO20401.1 - 1.5e-14 53.6 0.0 2.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EGO20401.1 - 0.057 12.7 0.1 0.16 11.2 0.0 1.7 1 1 0 1 1 1 0 Elongator subunit Iki1 Abhydrolase_3 PF07859.8 EGO20402.1 - 1.6e-25 89.9 0.0 2.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO20402.1 - 3.4e-16 58.8 0.0 4.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO20402.1 - 0.0089 15.7 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO20402.1 - 0.02 14.3 0.1 0.066 12.6 0.0 1.8 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EGO20402.1 - 0.03 13.7 0.0 0.073 12.4 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.16 EGO20402.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Metallophos PF00149.23 EGO20403.1 - 8.1e-09 35.1 2.1 6.1e-08 32.3 1.5 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO20403.1 - 0.00065 19.5 0.0 0.0037 17.1 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3220 PF11516.3 EGO20403.1 - 0.032 14.2 0.2 0.12 12.3 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3120) Ish1 PF10281.4 EGO20404.1 - 2.1e-50 168.3 36.5 4.6e-09 36.1 0.4 8.0 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein LEA_4 PF02987.11 EGO20404.1 - 3.5e-09 36.3 52.6 0.00016 21.4 5.2 6.0 4 1 1 5 5 5 5 Late embryogenesis abundant protein SAP PF02037.22 EGO20404.1 - 0.018 14.5 0.0 0.36 10.4 0.0 3.2 3 0 0 3 3 3 0 SAP domain TryThrA_C PF12319.3 EGO20404.1 - 0.25 10.4 37.5 0.073 12.2 3.1 4.7 3 2 2 5 5 5 0 Tryptophan-Threonine-rich plasmodium antigen C terminal zf-CCHC PF00098.18 EGO20405.1 - 5e-07 29.3 2.4 9.3e-07 28.4 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO20405.1 - 7.2e-05 22.7 6.5 0.00095 19.1 4.5 2.5 1 1 0 1 1 1 1 Retrotransposon gag protein CpXC PF14353.1 EGO20405.1 - 0.084 12.8 0.4 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 CpXC protein DUF2152 PF10222.4 EGO20406.1 - 0.15 10.2 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) O-FucT PF10250.4 EGO20407.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AA_permease_2 PF13520.1 EGO20408.1 - 8.6e-57 192.5 41.2 1.1e-56 192.2 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO20408.1 - 5.7e-17 61.2 33.9 8.1e-17 60.7 23.5 1.2 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.16 EGO20411.1 - 3.3e-55 186.9 0.0 4e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_18 PF13238.1 EGO20412.1 - 2.1e-29 102.4 0.3 1.6e-28 99.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO20412.1 - 2e-15 57.6 0.1 3.5e-15 56.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EGO20412.1 - 8.1e-06 25.7 0.4 4.2e-05 23.4 0.3 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 EGO20412.1 - 3.7e-05 23.8 0.0 9.9e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGO20412.1 - 3.8e-05 23.9 0.0 0.00011 22.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGO20412.1 - 5.8e-05 23.1 0.1 0.00024 21.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO20412.1 - 0.00011 21.9 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Thymidylate_kin PF02223.12 EGO20412.1 - 0.00011 21.6 0.2 0.14 11.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EGO20412.1 - 0.00011 22.0 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EGO20412.1 - 0.00077 18.6 1.6 0.19 10.8 0.0 2.1 2 0 0 2 2 2 2 KaiC ADK PF00406.17 EGO20412.1 - 0.0022 17.8 0.0 0.091 12.6 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 EGO20412.1 - 0.0024 17.1 0.0 0.0052 16.0 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 EGO20412.1 - 0.0028 17.5 0.1 0.15 11.9 0.0 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 EGO20412.1 - 0.0066 16.4 0.0 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EGO20412.1 - 0.0068 15.5 0.1 0.028 13.4 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EGO20412.1 - 0.0078 15.9 1.8 0.052 13.2 0.2 2.2 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 EGO20412.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 EGO20412.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EGO20412.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EGO20412.1 - 0.021 15.1 0.2 0.041 14.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 EGO20412.1 - 0.021 13.7 0.3 0.067 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) dNK PF01712.14 EGO20412.1 - 0.032 14.1 0.2 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ArgK PF03308.11 EGO20412.1 - 0.043 12.6 0.6 0.19 10.4 0.0 1.9 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 EGO20412.1 - 0.048 12.5 0.3 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein CoaE PF01121.15 EGO20412.1 - 0.05 13.0 0.5 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase RNA_helicase PF00910.17 EGO20412.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGO20412.1 - 0.07 12.7 0.1 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain DHquinase_II PF01220.14 EGO20412.1 - 0.076 12.3 0.3 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Dehydroquinase class II ELL PF10390.4 EGO20412.1 - 0.11 11.7 0.2 0.44 9.7 0.0 2.0 2 1 1 3 3 3 0 RNA polymerase II elongation factor ELL MobB PF03205.9 EGO20412.1 - 0.12 12.0 0.5 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGO20412.1 - 0.14 11.7 0.1 0.44 10.1 0.0 1.8 2 1 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 EGO20412.1 - 0.58 9.6 2.9 1.8 8.1 0.2 1.9 1 1 0 2 2 2 0 AAA domain OATP PF03137.15 EGO20414.1 - 0.01 13.9 3.0 0.95 7.4 0.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Membr_traf_MHD PF10540.4 EGO20415.1 - 2e-18 66.5 0.0 5.4e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EGO20415.1 - 2.8e-08 33.5 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain HSP70 PF00012.15 EGO20416.1 - 3.6e-80 269.5 6.2 3.6e-80 269.5 4.3 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGO20416.1 - 1.8e-05 23.5 1.5 6.6e-05 21.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.15 EGO20416.1 - 0.028 13.7 0.0 0.072 12.3 0.0 1.7 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Gp_dh_C PF02800.15 EGO20417.1 - 3.3e-74 247.5 0.0 4.5e-74 247.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EGO20417.1 - 2.5e-48 163.8 0.0 4.7e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PPR_3 PF13812.1 EGO20421.1 - 7.7e-08 32.0 1.1 0.0054 16.9 0.0 4.2 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGO20421.1 - 0.00021 21.2 0.1 0.3 11.1 0.0 2.8 2 2 1 3 3 3 2 PPR repeat family PPR PF01535.15 EGO20421.1 - 2.7 8.1 6.4 24 5.2 0.0 4.1 4 1 0 4 4 4 0 PPR repeat PPR_2 PF13041.1 EGO20422.1 - 0.00039 20.3 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 EGO20422.1 - 0.00072 19.6 0.2 0.0083 16.3 0.0 2.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain zf-CCHC PF00098.18 EGO20425.1 - 1.2e-08 34.4 4.7 2.1e-08 33.7 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO20425.1 - 0.028 14.1 2.8 0.062 13.0 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle HEAT PF02985.17 EGO20430.1 - 3.3e-11 42.2 2.3 0.00085 19.2 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EGO20430.1 - 2.1e-10 40.7 0.1 5.8e-06 26.4 0.0 2.6 1 1 0 2 2 2 2 HEAT repeats TRF PF08558.5 EGO20430.1 - 0.00031 20.1 0.5 0.0049 16.2 0.0 2.0 1 1 1 2 2 2 1 Telomere repeat binding factor (TRF) Proteasom_PSMB PF10508.4 EGO20430.1 - 0.00086 17.6 1.2 0.0026 16.0 0.8 1.7 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Psu PF07455.6 EGO20430.1 - 0.069 12.6 0.5 0.14 11.5 0.2 1.6 1 1 1 2 2 2 0 Phage polarity suppression protein (Psu) HEAT_EZ PF13513.1 EGO20430.1 - 0.21 12.1 2.1 3.8 8.1 0.1 3.1 3 1 0 3 3 3 0 HEAT-like repeat 4HBT_3 PF13622.1 EGO20431.1 - 3.2e-35 122.0 0.0 3.9e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EGO20431.1 - 1.6e-20 73.0 0.0 4.3e-15 55.5 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase XPA_C PF05181.7 EGO20432.1 - 2.7e-27 94.0 2.4 4.8e-27 93.3 1.7 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EGO20432.1 - 0.00074 19.1 5.9 0.00074 19.1 4.1 2.6 2 0 0 2 2 2 1 XPA protein N-terminal M-factor PF03855.8 EGO20432.1 - 0.35 10.8 1.8 0.66 10.0 1.3 1.4 1 0 0 1 1 1 0 M-factor APC_CDC26 PF10471.4 EGO20432.1 - 0.56 10.9 0.1 0.56 10.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 IncFII_repA PF02387.10 EGO20432.1 - 3.9 6.5 8.3 3.8 6.5 1.2 2.4 2 0 0 2 2 2 0 IncFII RepA protein family Transp_cyt_pur PF02133.10 EGO20434.1 - 6.3e-26 90.9 31.9 8.8e-26 90.4 22.1 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WD40 PF00400.27 EGO20436.1 - 3.3e-33 112.3 24.9 2e-11 43.2 0.5 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO20436.1 - 0.0011 17.1 5.6 0.013 13.6 0.6 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EGO20436.1 - 0.0087 14.9 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 EGO20436.1 - 0.03 14.0 0.0 1.2 8.8 0.0 2.9 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EGO20436.1 - 0.032 12.4 0.0 0.057 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EGO20436.1 - 0.036 12.3 0.5 5.9 5.0 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 EGO20436.1 - 0.042 13.5 12.5 3.9 7.2 0.0 6.6 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EGO20436.1 - 0.065 11.0 0.0 0.1 10.3 0.0 1.2 1 0 0 1 1 1 0 IKI3 family VID27 PF08553.5 EGO20436.1 - 0.22 9.7 0.1 3.8 5.6 0.0 2.0 2 0 0 2 2 2 0 VID27 cytoplasmic protein Ribosomal_L7Ae PF01248.21 EGO20437.1 - 4.1e-27 93.5 3.2 5.2e-27 93.1 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2042 PF09743.4 EGO20437.1 - 0.024 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Chromo_shadow PF01393.14 EGO20438.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Chromo shadow domain DUF2416 PF10315.4 EGO20439.1 - 1.4e-11 44.6 0.4 2e-11 44.0 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Abhydrolase_6 PF12697.2 EGO20440.1 - 1.6e-35 123.0 0.2 2.1e-35 122.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO20440.1 - 4.5e-23 82.0 0.0 5.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO20440.1 - 3.3e-18 65.8 0.1 5.2e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGO20440.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EGO20440.1 - 3.2e-07 30.1 0.0 1.7e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 EGO20440.1 - 0.00024 20.4 0.2 0.0088 15.3 0.1 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EGO20440.1 - 0.00098 18.3 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2048 PF09752.4 EGO20440.1 - 0.0071 15.2 0.2 0.74 8.6 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Peptidase_S28 PF05577.7 EGO20440.1 - 0.018 13.6 0.1 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S10 PF00450.17 EGO20440.1 - 0.14 11.3 0.0 4.5 6.3 0.0 2.2 1 1 1 2 2 2 0 Serine carboxypeptidase DUF3695 PF12494.3 EGO20441.1 - 0.14 11.8 0.6 2.3 7.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3695) Myb_DNA-bind_6 PF13921.1 EGO20443.1 - 2e-10 40.5 0.1 3.6e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO20443.1 - 4.8e-10 39.3 0.5 7.8e-10 38.6 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4085 PF13315.1 EGO20443.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF1518 PF07469.7 EGO20444.1 - 0.13 12.4 4.2 0.26 11.4 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) zf-LYAR PF08790.6 EGO20445.1 - 0.29 10.8 2.5 0.66 9.7 1.7 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger His_Phos_2 PF00328.17 EGO20449.1 - 7.5e-52 176.7 0.1 8.8e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 EGO20450.1 - 4.5e-57 193.9 0.0 5.2e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Coatomer_WDAD PF04053.9 EGO20452.1 - 6.3e-151 503.1 0.0 1.5e-150 501.8 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EGO20452.1 - 4.8e-48 159.4 9.8 3.3e-09 36.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGO20452.1 - 6.6e-05 22.6 0.2 4 7.2 0.0 5.4 5 1 1 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EGO20452.1 - 0.017 13.2 0.1 5.3 5.0 0.0 3.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Chitin_synth_2 PF03142.10 EGO20453.1 - 1.2e-238 792.7 0.1 1.7e-238 792.3 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGO20453.1 - 2.1e-118 396.2 0.0 4.1e-118 395.3 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 EGO20453.1 - 1.1e-18 67.9 0.0 1.6e-14 54.2 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EGO20453.1 - 1.1e-18 66.7 0.6 1.8e-12 46.8 0.0 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EGO20453.1 - 6.8e-16 58.5 4.8 6.8e-16 58.5 3.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EGO20453.1 - 6.6e-12 45.0 0.9 2.6e-11 43.1 0.6 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EGO20453.1 - 5.1e-08 32.7 0.0 3.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGO20453.1 - 5.2e-06 25.8 0.0 0.0035 16.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 21 NUDIX PF00293.23 EGO20454.1 - 6.3e-14 51.7 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CS PF04969.11 EGO20455.1 - 3.6e-18 65.8 0.1 6e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 CS domain Xan_ur_permease PF00860.15 EGO20457.1 - 6.5e-62 209.2 37.9 3.6e-61 206.7 22.7 2.7 2 1 0 2 2 2 1 Permease family Hist_deacetyl PF00850.14 EGO20458.1 - 1.3e-77 261.2 0.2 1.8e-77 260.6 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.20 EGO20459.1 - 1.8e-59 201.0 0.0 2.2e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO20459.1 - 4.2e-30 104.6 0.0 1e-29 103.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO20459.1 - 0.00024 20.1 0.0 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO20459.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family BRCT PF00533.21 EGO20460.1 - 1.5e-06 28.2 0.0 5.9e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EGO20460.1 - 3.4e-05 23.8 1.0 0.0001 22.3 0.7 1.8 1 1 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.2 EGO20460.1 - 0.00074 19.3 0.2 0.0085 15.9 0.0 2.6 2 1 0 2 2 2 1 twin BRCT domain DUF3006 PF11213.3 EGO20460.1 - 0.0036 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) SMN PF06003.7 EGO20461.1 - 8.3 5.4 14.8 10 5.1 10.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Lactamase_B PF00753.22 EGO20462.1 - 2.6e-10 40.2 0.1 2.9e-09 36.8 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO20462.1 - 0.00035 20.1 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ig PF00047.20 EGO20466.1 - 0.014 15.4 0.1 0.025 14.6 0.0 1.5 1 1 1 2 2 2 0 Immunoglobulin domain DUF4233 PF14017.1 EGO20468.1 - 0.024 14.5 0.1 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Retrotrans_gag PF03732.12 EGO20469.1 - 8.3e-06 25.7 0.2 8.3e-06 25.7 0.2 1.9 2 1 0 2 2 2 1 Retrotransposon gag protein HABP4_PAI-RBP1 PF04774.10 EGO20469.1 - 0.1 13.0 6.2 0.18 12.2 4.3 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family gag-asp_proteas PF13975.1 EGO20470.1 - 3.4e-05 23.5 0.2 0.0001 22.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO20470.1 - 0.0014 18.5 0.0 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO20470.1 - 0.0023 18.3 0.0 0.0046 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease 14-3-3 PF00244.15 EGO20470.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein Retrotrans_gag PF03732.12 EGO20472.1 - 0.00021 21.2 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 EGO20473.1 - 0.00056 19.8 0.0 0.0006 19.7 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO20473.1 - 0.058 13.2 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PepSY_TM_1 PF13172.1 EGO20474.1 - 4.8 7.0 7.3 0.85 9.4 1.8 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix Peptidase_M24 PF00557.19 EGO20481.1 - 3.6e-38 131.2 0.0 4.7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.4 EGO20482.1 - 9.1e-20 70.2 0.1 1.4e-16 59.6 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF3414 PF11894.3 EGO20482.1 - 4.3e-07 27.3 0.4 8.6e-07 26.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3414) TAF4 PF05236.9 EGO20483.1 - 1.8e-29 102.8 11.4 1e-28 100.3 7.9 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 EGO20483.1 - 0.089 12.4 0.0 0.089 12.4 0.0 2.4 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1675 PF07897.6 EGO20483.1 - 6.6 6.5 13.3 0.61 9.8 5.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF2874 PF11396.3 EGO20484.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Arb1 PF09692.5 EGO20485.1 - 0.00014 20.8 0.0 0.00074 18.4 0.0 2.0 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PH_4 PF15404.1 EGO20487.1 - 0.0076 15.7 0.7 0.013 15.0 0.5 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2347 PF09804.4 EGO20487.1 - 0.17 11.1 0.5 0.31 10.2 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) RecA PF00154.16 EGO20492.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EGO20492.1 - 0.01 15.2 0.0 0.03 13.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EGO20492.1 - 0.071 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GSH-S_N PF02951.9 EGO20494.1 - 0.04 13.7 0.1 0.056 13.2 0.1 1.3 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain I_LWEQ PF01608.12 EGO20494.1 - 0.078 12.9 0.5 0.098 12.6 0.4 1.1 1 0 0 1 1 1 0 I/LWEQ domain Takusan PF04822.8 EGO20494.1 - 0.1 12.3 3.3 0.13 12.0 1.4 1.7 2 0 0 2 2 2 0 Takusan Glyco_hydro_3 PF00933.16 EGO20497.1 - 1.6e-70 237.4 0.0 2.2e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO20497.1 - 2.7e-61 207.0 0.0 5.9e-61 205.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO20497.1 - 1.8e-19 69.4 0.0 3.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Oxysterol_BP PF01237.13 EGO20498.1 - 8.7e-110 366.5 0.0 1.2e-109 366.0 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EGO20498.1 - 9e-18 64.1 0.2 2.8e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EGO20498.1 - 0.00011 22.3 0.1 0.00087 19.4 0.1 2.5 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGO20498.1 - 0.00029 21.0 0.3 0.0079 16.4 0.0 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain Pet127 PF08634.5 EGO20498.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial protein Pet127 DNA_ligase_A_M PF01068.16 EGO20499.1 - 8.2e-53 178.7 0.1 1.6e-52 177.8 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO20499.1 - 6.5e-40 136.8 0.0 1.3e-39 135.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGO20499.1 - 8.6e-13 48.5 0.1 3.6e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EGO20499.1 - 3.1e-12 46.4 0.1 6.7e-06 26.1 0.0 3.1 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGO20499.1 - 0.11 12.4 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain Fork_head PF00250.13 EGO20500.1 - 3e-21 75.2 0.0 6.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Adaptin_N PF01602.15 EGO20501.1 - 4.5e-143 477.3 6.7 5.3e-143 477.1 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGO20501.1 - 7.1e-23 81.1 0.3 1.4e-22 80.1 0.2 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EGO20501.1 - 2e-06 27.9 4.3 0.2 11.9 0.1 5.6 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGO20501.1 - 0.0054 16.7 3.8 29 5.0 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.2 EGO20501.1 - 0.0062 16.4 4.2 0.3 10.9 0.4 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EGO20501.1 - 0.016 14.8 0.4 0.077 12.5 0.1 2.2 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) SPG48 PF14764.1 EGO20501.1 - 0.016 13.7 0.4 0.35 9.3 0.1 2.5 2 1 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking SBF PF01758.11 EGO20502.1 - 1.3e-45 155.1 15.9 1.3e-45 155.1 11.0 2.3 3 0 0 3 3 3 1 Sodium Bile acid symporter family Cation_ATPase_C PF00689.16 EGO20502.1 - 0.00059 19.4 0.3 0.00059 19.4 0.2 3.0 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus adh_short PF00106.20 EGO20503.1 - 2.1e-19 70.0 0.0 3.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20503.1 - 4.4e-10 39.5 0.3 7.2e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO20503.1 - 7e-08 32.5 0.0 9.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGO20503.1 - 0.00047 19.6 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO20503.1 - 0.038 12.8 0.1 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MoCF_biosynth PF00994.19 EGO20503.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Probable molybdopterin binding domain SF3b1 PF08920.5 EGO20504.1 - 3.3e-22 79.1 10.0 3.7e-21 75.7 6.9 2.8 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGO20504.1 - 6.4e-12 45.5 8.8 0.0001 22.4 0.0 7.0 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.17 EGO20504.1 - 8.1e-11 41.0 7.9 0.069 13.2 0.0 9.6 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EGO20504.1 - 5e-09 36.3 4.1 0.047 14.1 0.0 8.3 6 2 2 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGO20504.1 - 3.6e-07 30.4 1.4 0.67 10.3 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGO20504.1 - 1.7e-06 26.6 1.8 0.053 11.8 0.0 3.4 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EGO20504.1 - 0.00065 19.1 0.3 11 5.3 0.0 4.5 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 EGO20504.1 - 0.0032 16.8 2.0 2.8 7.2 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 EGO20504.1 - 0.08 12.8 0.2 9.7 6.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EGO20504.1 - 0.34 10.7 6.6 41 3.9 0.0 5.2 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 MFS_1 PF07690.11 EGO20505.1 - 1.9e-27 95.9 27.8 1.9e-27 95.9 19.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily EAP30 PF04157.11 EGO20506.1 - 2.6e-55 187.0 0.0 2.9e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Pterin_bind PF00809.17 EGO20506.1 - 0.013 14.9 1.9 0.11 11.8 0.1 2.2 1 1 1 2 2 2 0 Pterin binding enzyme TPR_11 PF13414.1 EGO20507.1 - 5.6e-08 32.3 0.1 0.00014 21.4 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO20507.1 - 1.2e-05 24.8 0.1 0.075 12.9 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO20507.1 - 2.1e-05 23.9 0.0 0.26 10.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO20507.1 - 3.9e-05 23.1 0.0 0.043 13.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO20507.1 - 0.00011 22.1 0.7 0.00074 19.4 0.1 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO20507.1 - 0.0043 17.4 0.0 0.16 12.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO20507.1 - 0.014 15.5 3.6 0.45 10.6 1.0 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGO20507.1 - 0.028 15.1 1.8 0.93 10.2 0.2 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO20507.1 - 0.24 12.1 1.7 2.5 8.9 1.1 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO20508.1 - 9.7e-13 47.5 0.2 1.6e-08 34.0 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGO20508.1 - 6.3e-10 38.2 0.6 0.0081 15.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO20508.1 - 5.1e-09 35.3 0.1 0.00088 19.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO20508.1 - 0.00015 21.6 0.7 0.0015 18.4 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO20508.1 - 0.00019 21.6 1.7 0.32 11.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO20508.1 - 0.0036 17.9 0.0 0.022 15.4 0.0 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO20508.1 - 0.0098 16.2 0.0 1.5 9.2 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO20508.1 - 0.012 16.1 0.0 0.19 12.4 0.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO20508.1 - 0.012 15.7 0.5 0.049 13.7 0.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EGO20508.1 - 0.013 14.8 1.0 0.11 11.8 0.1 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_8 PF13181.1 EGO20508.1 - 0.017 14.8 0.3 12 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 EGO20508.1 - 0.02 14.7 1.1 0.046 13.5 0.7 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) YfiO PF13525.1 EGO20508.1 - 0.033 13.6 0.5 0.084 12.3 0.1 1.8 1 1 0 1 1 1 0 Outer membrane lipoprotein TPR_7 PF13176.1 EGO20508.1 - 0.041 13.6 0.1 0.7 9.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3361 PF11841.3 EGO20508.1 - 0.07 12.8 0.7 0.29 10.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) Metallothio_Pro PF02069.11 EGO20508.1 - 3.8 7.4 9.0 4.2 7.2 0.0 2.6 3 0 0 3 3 2 0 Prokaryotic metallothionein FAD_binding_3 PF01494.14 EGO20509.1 - 1.7e-22 79.9 3.2 2.7e-12 46.4 0.0 3.3 3 1 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 EGO20509.1 - 7.3e-07 28.4 0.9 0.00011 21.2 0.2 3.1 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EGO20509.1 - 5.8e-06 25.4 1.1 0.00067 18.6 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO20509.1 - 7.4e-06 24.8 0.2 0.0034 16.0 0.2 2.8 2 1 1 3 3 3 2 Tryptophan halogenase SE PF08491.5 EGO20509.1 - 0.00021 20.1 0.0 0.00038 19.3 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EGO20509.1 - 0.00043 20.0 0.8 0.0056 16.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO20509.1 - 0.00056 19.8 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO20509.1 - 0.0063 16.5 0.1 0.022 14.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO20509.1 - 0.0068 15.5 0.1 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EGO20509.1 - 0.0072 16.3 0.2 0.0072 16.3 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO20509.1 - 0.022 15.1 2.6 0.04 14.3 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO20509.1 - 0.062 12.1 0.6 0.17 10.7 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain Sec6 PF06046.8 EGO20510.1 - 3.1e-147 491.0 1.2 1.2e-146 489.1 0.1 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EGO20510.1 - 0.012 14.4 5.8 0.028 13.2 2.6 2.4 1 1 1 3 3 3 0 Vps53-like, N-terminal HECT PF00632.20 EGO20510.1 - 0.031 13.4 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Snf7 PF03357.16 EGO20510.1 - 0.049 13.0 8.3 0.29 10.4 5.8 2.4 1 1 0 1 1 1 0 Snf7 CN_hydrolase PF00795.17 EGO20511.1 - 1.8e-27 95.8 0.0 3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EGO20511.1 - 1.5e-23 83.0 0.0 4.2e-23 81.5 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EGO20511.1 - 0.0034 16.9 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase ACC_central PF08326.7 EGO20512.1 - 3.7e-207 689.7 0.0 4.7e-207 689.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGO20512.1 - 5.2e-167 556.1 0.0 6.7e-167 555.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGO20512.1 - 9.8e-52 175.3 0.0 1.8e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGO20512.1 - 2.4e-21 75.8 0.0 5e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGO20512.1 - 3.4e-20 72.0 0.0 2.8e-19 69.0 0.0 2.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGO20512.1 - 5.8e-14 51.4 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGO20512.1 - 3.3e-11 43.2 0.0 7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGO20512.1 - 8.8e-10 37.8 0.0 0.00019 20.3 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGO20512.1 - 0.00066 19.5 0.1 0.0034 17.2 0.0 2.2 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO20512.1 - 0.0019 17.6 0.0 0.0043 16.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGO20512.1 - 0.033 13.5 0.1 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EGO20512.1 - 0.14 11.6 0.0 0.96 8.8 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Peptidase_M20 PF01546.23 EGO20513.1 - 3.6e-22 78.7 0.0 5.7e-22 78.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO20513.1 - 1e-08 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGO20513.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 Dynein_light PF01221.13 EGO20515.1 - 4.9e-37 125.8 0.6 5.3e-37 125.6 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EGO20515.1 - 0.078 13.3 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain He_PIG PF05345.7 EGO20516.1 - 1.1e-08 34.9 7.8 2.1e-06 27.6 0.4 5.5 5 0 0 5 5 5 1 Putative Ig domain G2F PF07474.7 EGO20516.1 - 0.23 10.7 1.5 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 G2F domain HEAT_EZ PF13513.1 EGO20517.1 - 4.6e-18 65.1 16.8 2.5e-05 24.6 0.0 10.3 10 1 1 11 11 11 4 HEAT-like repeat HEAT_2 PF13646.1 EGO20517.1 - 6e-17 61.7 10.3 9e-05 22.6 0.1 7.7 4 4 4 9 9 9 7 HEAT repeats HEAT PF02985.17 EGO20517.1 - 6.4e-15 53.8 16.7 0.0051 16.7 0.0 9.3 10 0 0 10 10 10 3 HEAT repeat IBN_N PF03810.14 EGO20517.1 - 8.4e-11 41.6 3.7 3.2e-10 39.7 0.2 3.5 3 1 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 EGO20517.1 - 7.2e-08 32.2 1.2 0.0035 17.0 0.1 4.7 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EGO20517.1 - 7.3e-08 31.1 2.3 0.36 9.0 0.1 4.9 5 1 0 5 5 5 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EGO20517.1 - 3.3e-05 24.1 0.0 0.021 15.1 0.0 4.4 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EGO20517.1 - 4.2e-05 23.4 0.3 0.59 10.1 0.0 5.3 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 EGO20517.1 - 0.0015 18.4 0.1 4.3 7.1 0.0 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGO20517.1 - 0.0033 16.8 0.2 6.6 6.0 0.0 5.1 5 2 2 7 7 7 1 CLASP N terminal MMS19_C PF12460.3 EGO20517.1 - 0.044 12.5 3.6 25 3.4 0.0 4.8 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal BTB PF00651.26 EGO20518.1 - 1.5e-06 28.1 0.9 6.7e-05 22.8 0.2 2.7 2 1 0 2 2 2 1 BTB/POZ domain DHO_dh PF01180.16 EGO20519.1 - 9.8e-95 316.9 0.0 1.2e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EGO20519.1 - 0.024 13.4 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.14 EGO20520.1 - 6.9e-42 143.3 0.0 6.7e-30 103.7 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO20520.1 - 1.1e-12 48.4 0.0 1.9e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO20520.1 - 2.4e-08 33.3 0.2 4.9e-06 25.6 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO20520.1 - 2.4e-05 24.1 0.0 0.00012 21.9 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO20520.1 - 3.5e-05 23.7 0.5 0.00013 21.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO20520.1 - 0.00039 20.3 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO20520.1 - 0.091 11.6 0.0 0.25 10.2 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Malic_M PF03949.10 EGO20520.1 - 0.096 12.2 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain AIG1 PF04548.11 EGO20522.1 - 3.7e-08 32.7 0.0 4.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EGO20522.1 - 5.7e-07 29.4 0.0 8.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGO20522.1 - 9.6e-05 22.2 0.3 0.0052 16.6 0.1 2.2 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 EGO20522.1 - 0.00047 19.3 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGO20522.1 - 0.00066 19.9 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EGO20522.1 - 0.00066 20.4 0.1 0.0015 19.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO20522.1 - 0.0059 16.0 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EGO20522.1 - 0.0079 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF87 PF01935.12 EGO20522.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 Ras PF00071.17 EGO20522.1 - 0.011 15.0 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 0 Ras family Zeta_toxin PF06414.7 EGO20522.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EGO20522.1 - 0.015 14.7 0.1 0.031 13.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Miro PF08477.8 EGO20522.1 - 0.032 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EGO20522.1 - 0.041 13.4 0.2 0.26 10.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_13 PF13166.1 EGO20522.1 - 0.042 12.3 0.1 0.054 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO20522.1 - 0.059 13.3 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO20522.1 - 0.062 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGO20522.1 - 0.086 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO20522.1 - 0.14 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family FMO-like PF00743.14 EGO20523.1 - 4.7e-40 137.2 0.0 3.6e-28 98.0 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO20523.1 - 2.9e-11 43.8 0.0 6.3e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO20523.1 - 3.7e-06 26.0 0.0 0.00037 19.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO20523.1 - 8.7e-06 25.5 0.0 5.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO20523.1 - 6.1e-05 22.9 0.0 0.00045 20.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO20523.1 - 0.025 13.4 0.9 0.087 11.7 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO20523.1 - 0.04 13.8 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EGO20523.1 - 0.11 12.0 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Lambda_CIII PF02061.11 EGO20523.1 - 2.7 8.0 5.2 7.4 6.6 0.1 2.8 3 0 0 3 3 3 0 Lambda Phage CIII Ribosomal_L23 PF00276.15 EGO20525.1 - 8.5e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Metallophos PF00149.23 EGO20526.1 - 4.1e-09 36.1 0.0 1.9e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO20526.1 - 3.3e-06 27.0 0.1 1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LRR_8 PF13855.1 EGO20527.1 - 1.2e-15 56.9 17.5 1.4e-09 37.5 4.1 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EGO20527.1 - 1.1e-14 53.5 22.6 5.2e-08 32.3 2.6 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO20527.1 - 7.7e-12 43.5 8.3 0.0042 16.9 0.3 5.1 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_7 PF13504.1 EGO20527.1 - 9.7e-05 21.9 7.4 0.057 13.6 0.2 4.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 EGO20527.1 - 0.03 14.3 5.9 0.34 11.1 0.4 3.6 3 0 0 3 3 3 0 Leucine Rich repeat FSA_C PF10479.4 EGO20527.1 - 0.068 11.2 0.1 0.099 10.7 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DDE_1 PF03184.14 EGO20529.1 - 1.5e-12 47.1 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Asp PF00026.18 EGO20532.1 - 6.6e-71 239.1 9.8 8.1e-71 238.8 6.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO20532.1 - 2e-07 31.1 0.5 9.9e-07 28.8 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGO20532.1 - 0.013 15.0 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Terpene_synth_C PF03936.11 EGO20533.1 - 5.2e-12 45.5 0.7 7.3e-12 45.0 0.5 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Asp PF00026.18 EGO20534.1 - 2.8e-56 191.0 0.9 3.4e-56 190.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO20534.1 - 2.2e-09 37.4 1.9 2.3e-08 34.1 0.2 2.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal DHBP_synthase PF00926.14 EGO20535.1 - 5.5e-75 250.8 0.0 6.6e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.22 EGO20536.1 - 4.6e-33 112.7 9.3 9e-19 66.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_fiss_reg PF05308.6 EGO20541.1 - 0.48 9.7 3.1 0.24 10.7 0.5 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator RbsD_FucU PF05025.8 EGO20543.1 - 0.052 13.8 1.0 0.1 12.9 0.7 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family BMFP PF04380.8 EGO20545.1 - 0.0056 16.7 0.1 1.6 8.9 0.2 2.3 2 0 0 2 2 2 2 Membrane fusogenic activity WD40 PF00400.27 EGO20546.1 - 4.1e-86 280.0 28.5 1.8e-11 43.4 0.7 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EGO20546.1 - 5.2e-08 31.4 6.2 0.012 13.7 0.0 4.5 3 1 0 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 EGO20546.1 - 1.4e-06 28.1 0.1 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nucleoporin_N PF08801.6 EGO20546.1 - 7e-05 21.7 0.7 0.15 10.7 0.0 3.9 3 1 0 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.1 EGO20546.1 - 0.05 12.6 0.1 31 3.5 0.0 3.5 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EGO20546.1 - 0.075 11.3 0.7 8.7 4.5 0.1 2.6 2 1 0 3 3 3 0 Cytochrome D1 heme domain RhoGEF PF00621.15 EGO20548.1 - 3.6e-35 121.4 0.0 4.9e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EGO20548.1 - 2e-19 69.2 8.4 3.3e-19 68.5 5.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EGO20548.1 - 0.025 14.7 0.1 0.23 11.6 0.0 2.5 2 1 0 2 2 2 0 PH domain FYVE_2 PF02318.11 EGO20548.1 - 0.65 9.9 6.0 1.4 8.8 4.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_76 PF03663.9 EGO20549.1 - 7.7e-21 74.8 20.7 2.5e-20 73.2 14.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Thymidylate_kin PF02223.12 EGO20550.1 - 8e-44 149.2 0.0 9.6e-44 148.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EGO20550.1 - 0.012 14.7 0.0 0.03 13.5 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGO20550.1 - 0.023 15.5 0.1 0.039 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 EGO20550.1 - 0.032 13.8 0.1 0.16 11.6 0.0 1.9 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Meth_synt_1 PF08267.7 EGO20550.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain UQ_con PF00179.21 EGO20551.1 - 3.3e-24 84.9 0.1 3.9e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MMR_HSR1 PF01926.18 EGO20552.1 - 3.8e-11 42.9 0.0 6.3e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EGO20552.1 - 6e-06 25.7 0.1 1.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO20552.1 - 1.2e-05 25.8 0.0 1.9e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EGO20552.1 - 3.1e-05 23.1 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.22 EGO20552.1 - 6.6e-05 23.2 0.1 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EGO20552.1 - 8.9e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO20552.1 - 0.00021 21.1 0.2 0.00049 19.9 0.1 1.5 1 1 0 1 1 1 1 Dynamin family AAA_10 PF12846.2 EGO20552.1 - 0.0028 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain IIGP PF05049.8 EGO20552.1 - 0.0057 15.5 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF815 PF05673.8 EGO20552.1 - 0.011 14.6 0.1 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EGO20552.1 - 0.012 15.1 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EGO20552.1 - 0.017 15.2 0.1 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGO20552.1 - 0.018 15.3 1.0 0.03 14.6 0.7 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGO20552.1 - 0.032 14.0 0.2 0.053 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EGO20552.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGO20552.1 - 0.059 12.6 0.1 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Zeta_toxin PF06414.7 EGO20552.1 - 0.085 11.9 0.2 0.2 10.7 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 EGO20552.1 - 0.098 12.6 0.1 0.2 11.6 0.1 1.6 1 1 1 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 EGO20552.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EGO20552.1 - 0.12 11.8 0.1 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Peptidase_S28 PF05577.7 EGO20553.1 - 1.1e-48 165.9 1.9 1.2e-47 162.5 1.3 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGO20553.1 - 2.7e-05 23.4 0.2 7.6e-05 22.0 0.2 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family UQ_con PF00179.21 EGO20554.1 - 1.4e-16 60.2 0.0 1.5e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGO20554.1 - 0.0086 15.9 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EGO20554.1 - 0.042 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain VHS PF00790.14 EGO20555.1 - 3.6e-31 107.7 0.2 6.6e-31 106.8 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EGO20555.1 - 1.4e-15 56.5 0.1 3.4e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO20555.1 - 1.5e-13 49.9 0.1 2.8e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO20555.1 - 1.7e-13 49.7 0.0 3.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain GAT PF03127.9 EGO20555.1 - 7.5e-05 22.6 0.4 0.00023 21.0 0.3 1.9 1 0 0 1 1 1 1 GAT domain HEAT_2 PF13646.1 EGO20555.1 - 0.035 14.3 0.7 0.1 12.9 0.5 1.8 1 0 0 1 1 1 0 HEAT repeats ThiC-associated PF13667.1 EGO20555.1 - 0.044 13.3 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 ThiC-associated domain UNC45-central PF11701.3 EGO20555.1 - 0.17 11.4 0.2 0.35 10.4 0.2 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central UIM PF02809.15 EGO20555.1 - 0.24 11.0 4.1 0.071 12.7 0.4 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif Pro_isomerase PF00160.16 EGO20556.1 - 1.9e-39 135.3 0.3 7.7e-39 133.3 0.0 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.18 EGO20557.1 - 7.3e-07 29.1 0.0 7.7e-06 25.8 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO20557.1 - 0.00034 19.8 0.1 0.00071 18.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGO20557.1 - 0.0032 17.7 0.0 0.0093 16.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.11 EGO20557.1 - 0.011 14.8 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 EGO20557.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 EGO20557.1 - 0.026 15.0 0.0 0.25 11.8 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EGO20557.1 - 0.032 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EGO20557.1 - 0.041 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Y_phosphatase PF00102.22 EGO20557.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Dynamin_N PF00350.18 EGO20557.1 - 0.045 13.5 0.0 0.094 12.5 0.0 1.7 1 1 0 1 1 1 0 Dynamin family AAA_22 PF13401.1 EGO20557.1 - 0.084 13.0 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO20557.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EGO20558.1 - 2.8e-45 154.0 3.3 6.3e-25 88.0 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGO20558.1 - 1.4e-20 74.4 4.1 7.8e-07 29.3 0.1 4.3 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EGO20558.1 - 5.9e-13 48.5 2.3 7.7e-05 22.0 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA PF00004.24 EGO20558.1 - 3.9e-09 36.7 0.3 0.0021 18.2 0.0 3.7 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO20558.1 - 1.3e-08 35.0 1.5 0.0004 20.5 0.2 3.5 3 1 0 3 3 3 2 AAA domain ABC_tran_2 PF12848.2 EGO20558.1 - 6.7e-08 32.2 3.7 6.7e-08 32.2 2.6 2.4 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 EGO20558.1 - 1.6e-07 31.2 0.1 0.00036 20.3 0.0 2.9 3 0 0 3 3 2 2 Archaeal ATPase AAA_15 PF13175.1 EGO20558.1 - 2.1e-07 30.3 0.2 1.9 7.4 0.0 4.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 EGO20558.1 - 1.3e-06 28.3 0.3 0.14 12.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EGO20558.1 - 2.5e-06 27.6 2.4 0.042 13.8 0.0 3.8 3 2 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EGO20558.1 - 2.5e-06 26.7 1.0 0.0031 16.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGO20558.1 - 3.4e-06 26.9 0.2 0.077 12.8 0.1 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGO20558.1 - 3.6e-06 27.4 0.0 0.012 16.0 0.0 3.1 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EGO20558.1 - 4.8e-06 26.3 0.0 0.029 14.0 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EGO20558.1 - 2.7e-05 24.9 1.2 0.43 11.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.20 EGO20558.1 - 4.3e-05 23.1 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EGO20558.1 - 5.6e-05 22.8 1.8 0.4 10.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EGO20558.1 - 6.2e-05 23.1 0.1 0.53 10.4 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA_29 PF13555.1 EGO20558.1 - 7.4e-05 22.2 0.0 0.091 12.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EGO20558.1 - 7.4e-05 22.3 1.6 0.26 10.6 0.0 3.4 4 0 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 EGO20558.1 - 0.00013 21.9 0.1 0.013 15.4 0.0 3.5 3 0 0 3 3 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGO20558.1 - 0.00034 20.4 0.0 0.16 11.9 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGO20558.1 - 0.00046 20.5 0.2 0.00046 20.5 0.2 3.9 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EGO20558.1 - 0.00051 20.0 0.9 0.0081 16.1 0.0 2.9 3 1 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 EGO20558.1 - 0.0016 17.9 0.5 0.27 10.7 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 EGO20558.1 - 0.002 17.0 0.0 1.6 7.5 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 EGO20558.1 - 0.0024 16.8 0.2 1.8 7.3 0.0 2.7 2 1 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.1 EGO20558.1 - 0.0062 15.9 0.0 1.8 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO20558.1 - 0.0071 15.8 0.0 0.34 10.3 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EGO20558.1 - 0.011 15.4 0.1 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EGO20558.1 - 0.017 14.2 0.0 6.8 5.7 0.0 3.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO20558.1 - 0.028 14.1 4.2 13 5.5 0.0 4.1 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 EGO20558.1 - 0.029 13.6 5.2 0.11 11.7 0.1 3.7 3 2 1 4 4 4 0 Ferrous iron transport protein B AAA_19 PF13245.1 EGO20558.1 - 0.11 12.2 0.0 4.4 7.1 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain Arf PF00025.16 EGO20558.1 - 0.12 11.5 3.0 0.3 10.3 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family AAA_18 PF13238.1 EGO20558.1 - 0.32 11.3 3.4 3.5 7.9 0.0 3.6 3 1 0 3 3 3 0 AAA domain Tmemb_170 PF10190.4 EGO20559.1 - 0.074 13.1 0.6 0.074 13.1 0.4 2.1 2 0 0 2 2 2 0 Putative transmembrane protein 170 PS_Dcarbxylase PF02666.10 EGO20560.1 - 3.9e-46 156.9 0.0 5.2e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Terpene_synth_C PF03936.11 EGO20563.1 - 0.01 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain TRI5 PF06330.6 EGO20564.1 - 0.0014 17.3 0.8 0.0015 17.2 0.6 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 EGO20565.1 - 2.6e-13 49.8 1.2 4e-13 49.2 0.8 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RIH_assoc PF08454.6 EGO20565.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated MKT1_C PF12246.3 EGO20569.1 - 5.6e-60 202.3 0.0 7.3e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication zf-C2H2_6 PF13912.1 EGO20570.1 - 0.00013 21.7 1.2 0.00031 20.5 0.1 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EGO20570.1 - 0.0021 18.1 0.1 0.0059 16.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO20570.1 - 0.018 15.1 0.1 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGO20570.1 - 0.075 13.4 0.3 0.075 13.4 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO20570.1 - 2.2 8.7 4.6 0.46 10.9 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger O-FucT PF10250.4 EGO20572.1 - 1.4e-09 37.5 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aldo_ket_red PF00248.16 EGO20573.1 - 5.3e-45 153.4 0.0 6.1e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.18 EGO20576.1 - 0.00012 21.7 2.5 0.00024 20.8 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Acyl-CoA_dh_1 PF00441.19 EGO20577.1 - 2.1e-27 96.0 0.4 3e-27 95.5 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EGO20577.1 - 9.4e-18 63.8 0.0 1.9e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EGO20577.1 - 3.5e-16 58.4 0.1 6.8e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGO20577.1 - 7.3e-11 42.6 0.0 3.9e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO20577.1 - 0.026 14.7 0.3 0.055 13.7 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Arginosuc_synth PF00764.14 EGO20579.1 - 9.7e-152 505.4 0.0 1.2e-151 505.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EGO20579.1 - 8.6e-05 21.9 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EGO20579.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 EGO20579.1 - 0.026 13.0 0.0 0.044 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase HAD PF12710.2 EGO20579.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1680 PF07944.7 EGO20580.1 - 6e-23 80.9 0.1 7.2e-22 77.3 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) ECR1_N PF14382.1 EGO20581.1 - 3.4e-15 55.0 0.0 5.9e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EGO20581.1 - 0.00056 19.8 0.0 0.64 10.0 0.0 2.4 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 zf-MYND PF01753.13 EGO20582.1 - 5.7e-08 32.5 15.2 1.4e-07 31.3 10.5 1.7 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 EGO20582.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.1 EGO20582.1 - 0.64 9.9 10.4 0.57 10.0 5.8 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RRM_1 PF00076.17 EGO20583.1 - 6.2e-15 54.5 0.0 9.9e-15 53.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO20583.1 - 1.2e-11 44.3 0.0 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO20583.1 - 2.5e-06 27.2 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 EGO20583.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain ATG27 PF09451.5 EGO20584.1 - 0.048 12.8 0.1 0.086 12.0 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Smr PF01713.16 EGO20585.1 - 5.2e-10 39.3 0.3 1.7e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EGO20585.1 - 0.00015 21.6 3.9 0.00031 20.6 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Acetyltransf_10 PF13673.1 EGO20586.1 - 3.4e-06 27.1 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO20586.1 - 0.00017 21.5 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO20586.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain O-FucT PF10250.4 EGO20588.1 - 4.2e-05 22.8 0.0 6.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3141 PF11339.3 EGO20588.1 - 0.087 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) RabGAP-TBC PF00566.13 EGO20589.1 - 3e-49 167.3 0.0 5.8e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_8 PF13833.1 EGO20589.1 - 2.8e-06 26.8 0.7 0.12 12.0 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO20589.1 - 3.8e-06 26.3 1.0 0.0053 16.5 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EGO20589.1 - 1.5e-05 24.9 1.5 0.00021 21.3 0.7 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGO20589.1 - 2e-05 23.5 0.1 0.0032 16.6 0.1 2.8 2 0 0 2 2 2 1 EF hand GRAM PF02893.15 EGO20589.1 - 0.0083 15.6 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 GRAM domain WD40 PF00400.27 EGO20590.1 - 7.9e-61 199.9 23.4 1.1e-12 47.3 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EGO20590.1 - 1e-09 38.3 0.2 0.013 15.2 0.0 3.9 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGO20590.1 - 2.5e-06 25.9 8.0 0.0034 15.5 0.3 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EGO20590.1 - 7.7e-05 22.1 1.2 0.008 15.5 0.1 2.8 2 2 2 4 4 4 1 Cytolethal distending toxin A/C family Nucleoporin_N PF08801.6 EGO20590.1 - 0.0028 16.4 4.8 0.49 9.0 0.2 3.8 1 1 2 3 3 3 2 Nup133 N terminal like DUF1513 PF07433.6 EGO20590.1 - 0.011 14.6 0.2 1 8.1 0.0 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EGO20590.1 - 0.08 11.2 0.0 0.24 9.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ricin_B_lectin PF00652.17 EGO20590.1 - 0.093 12.7 1.3 1.1 9.2 0.2 2.9 2 2 1 3 3 3 0 Ricin-type beta-trefoil lectin domain MMR_HSR1 PF01926.18 EGO20591.1 - 7.4e-14 51.7 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGO20591.1 - 4.2e-07 29.9 0.0 0.0031 17.3 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EGO20591.1 - 3.4e-06 26.3 0.0 4.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EGO20591.1 - 0.0008 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EGO20591.1 - 0.0039 16.2 0.0 0.045 12.7 0.0 2.3 1 1 0 1 1 1 1 Septin AAA_29 PF13555.1 EGO20591.1 - 0.0043 16.5 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGO20591.1 - 0.015 14.7 0.0 0.2 11.0 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGO20591.1 - 0.02 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.1 EGO20591.1 - 0.049 12.6 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGO20591.1 - 0.059 13.5 0.2 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGO20591.1 - 0.12 11.8 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EGO20591.1 - 0.13 11.9 0.1 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 EGO20591.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF2263 PF10021.4 EGO20595.1 - 1.4e-13 51.1 0.0 3.3e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Pirin PF02678.11 EGO20596.1 - 1.1e-23 83.0 1.3 1.9e-23 82.3 0.9 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EGO20596.1 - 0.0025 17.2 2.7 0.039 13.4 0.5 2.3 2 0 0 2 2 2 1 Cupin domain eRF1_1 PF03463.10 EGO20596.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 1 FAD_oxidored PF12831.2 EGO20597.1 - 0.008 15.2 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2236 PF09995.4 EGO20597.1 - 0.019 14.2 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) RTC4 PF14474.1 EGO20600.1 - 9.4e-24 83.7 0.0 3.1e-23 82.0 0.0 1.9 1 0 0 1 1 1 1 RTC4-like domain PTS_2-RNA PF01885.11 EGO20601.1 - 4.1e-59 199.0 0.0 5.4e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2183 PF09949.4 EGO20602.1 - 1.3e-27 95.6 0.0 6.6e-27 93.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) TPR_11 PF13414.1 EGO20603.1 - 8.5e-11 41.3 0.0 2.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO20603.1 - 1.1e-07 31.2 0.0 0.022 14.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO20603.1 - 6.4e-05 22.8 0.0 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO20603.1 - 0.00016 21.1 0.0 0.13 11.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO20603.1 - 0.073 13.4 0.0 0.59 10.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Sec23_Sec24 PF04810.10 EGO20604.1 - 0.022 14.3 0.4 0.041 13.4 0.1 1.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rtf2 PF04641.7 EGO20604.1 - 0.11 11.7 1.9 0.2 10.7 1.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Rrn6 PF10214.4 EGO20604.1 - 1.8 6.5 3.9 2.5 6.1 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF383 PF04063.9 EGO20605.1 - 8.5e-54 182.0 0.0 1.9e-53 180.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGO20605.1 - 9.8e-18 63.4 0.4 2.2e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 EGO20605.1 - 0.032 12.5 0.1 4.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit RVP_2 PF08284.6 EGO20606.1 - 0.033 14.1 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO20608.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO20608.1 - 0.00016 22.0 0.0 0.00023 21.6 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO20608.1 - 0.043 13.7 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease AICARFT_IMPCHas PF01808.13 EGO20610.1 - 1.3e-107 359.5 0.0 1.6e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGO20610.1 - 8.2e-24 83.3 0.0 1.4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.1 EGO20611.1 - 1.1e-37 129.3 0.6 1.3e-37 129.0 0.4 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGO20611.1 - 1.3e-07 31.6 0.5 1.9e-07 31.1 0.4 1.3 1 0 0 1 1 1 1 HD domain PARP PF00644.15 EGO20612.1 - 4.8e-14 52.2 0.8 2.3e-09 37.0 0.0 3.2 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain RPAP2_Rtr1 PF04181.8 EGO20612.1 - 0.00079 19.4 11.9 1.1 9.4 0.5 5.3 3 1 0 3 3 3 1 Rtr1/RPAP2 family Perm-CXXC PF15629.1 EGO20612.1 - 0.035 14.0 2.0 0.13 12.3 1.4 1.9 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Paired_CXXCH_1 PF09699.5 EGO20612.1 - 0.11 12.0 4.9 0.55 9.7 0.0 3.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) API5 PF05918.6 EGO20612.1 - 0.17 10.3 0.2 0.24 9.8 0.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fer4_11 PF13247.1 EGO20612.1 - 2.9 7.8 24.4 1.6 8.6 5.7 3.6 3 1 1 4 4 4 0 4Fe-4S dicluster domain DUF329 PF03884.9 EGO20612.1 - 6.8 6.3 25.8 0.3 10.6 0.4 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF329) Ribonuclease PF00545.15 EGO20617.1 - 0.00013 22.0 0.0 0.00027 20.9 0.0 1.5 1 1 0 1 1 1 1 ribonuclease DUF3950 PF13132.1 EGO20619.1 - 0.044 13.3 0.1 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Bac_thur_toxin PF01338.13 EGO20620.1 - 0.12 11.5 2.7 0.14 11.3 0.1 2.0 2 0 0 2 2 2 0 Bacillus thuringiensis toxin DLH PF01738.13 EGO20622.1 - 1e-22 80.5 0.0 1.1e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO20622.1 - 8e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO20622.1 - 0.0073 16.2 0.0 0.076 12.8 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EGO20623.1 - 2.3e-21 76.1 0.0 2.6e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO20623.1 - 1.8e-05 24.5 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO20623.1 - 0.0066 16.3 0.0 0.035 14.0 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S24 PF00717.18 EGO20624.1 - 9.5e-09 34.7 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGO20624.1 - 8e-07 28.6 0.0 3e-05 23.5 0.0 2.5 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 AA_permease PF00324.16 EGO20625.1 - 1.5e-122 409.4 39.1 1.8e-122 409.1 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO20625.1 - 5.2e-38 130.6 44.0 6.3e-38 130.4 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease DDE_1 PF03184.14 EGO20629.1 - 4.7e-34 117.4 0.5 7.5e-34 116.7 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EGO20629.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Dfp1_Him1_M PF08630.5 EGO20630.1 - 0.07 12.9 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Dfp1/Him1, central region AF-4 PF05110.8 EGO20631.1 - 0.018 12.9 0.3 0.022 12.6 0.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein F-box PF00646.28 EGO20633.1 - 0.038 13.6 1.5 0.094 12.4 1.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.1 EGO20633.1 - 4.3 7.1 5.4 1.7 8.3 1.7 1.8 2 0 0 2 2 2 0 F-box-like domain DDE_1 PF03184.14 EGO20634.1 - 9.4e-26 90.2 0.0 1.3e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PUF PF00806.14 EGO20634.1 - 0.12 11.8 0.1 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat FAD_binding_3 PF01494.14 EGO20635.1 - 6e-46 157.1 0.1 1.5e-31 109.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO20635.1 - 4.1e-08 32.5 0.1 0.0056 15.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGO20635.1 - 9.3e-07 28.2 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO20635.1 - 6.7e-06 26.3 0.3 2e-05 24.7 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO20635.1 - 1.3e-05 25.2 0.3 4.8e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EGO20635.1 - 0.00088 19.1 0.5 0.0021 17.8 0.1 1.8 2 0 0 2 2 2 1 ThiF family Thi4 PF01946.12 EGO20635.1 - 0.0014 17.7 0.0 0.061 12.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EGO20635.1 - 0.0022 16.9 0.7 0.006 15.4 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 EGO20635.1 - 0.0029 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.9 EGO20635.1 - 0.0041 15.6 0.2 0.37 9.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO20635.1 - 0.012 15.6 0.3 0.043 13.8 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EGO20635.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EGO20635.1 - 0.048 13.4 1.0 0.19 11.4 0.1 2.4 3 0 0 3 3 2 0 FAD-NAD(P)-binding Hydrolase_like2 PF13246.1 EGO20635.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Lycopene_cycl PF05834.7 EGO20635.1 - 0.15 10.9 0.5 1.3 7.8 0.3 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EGO20635.1 - 0.17 10.6 2.8 1.4 7.7 1.9 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGO20635.1 - 0.28 9.7 1.6 9 4.7 0.0 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Na_Ca_ex PF01699.19 EGO20637.1 - 1.7e-10 40.6 19.2 3.7e-08 33.0 2.3 2.3 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Cytochrom_B_N PF00033.14 EGO20637.1 - 0.031 13.6 1.3 0.055 12.8 0.9 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF575 PF04746.7 EGO20637.1 - 0.12 12.3 1.4 0.24 11.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF575) GWT1 PF06423.7 EGO20637.1 - 0.51 10.4 3.8 10 6.2 0.1 2.4 2 0 0 2 2 2 0 GWT1 DUF3185 PF11381.3 EGO20637.1 - 2.6 7.8 7.0 14 5.5 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) FUN14 PF04930.10 EGO20638.1 - 9.2e-20 70.7 0.3 2.4e-19 69.4 0.1 1.7 2 0 0 2 2 2 1 FUN14 family GerPB PF10803.3 EGO20638.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Spore germination GerPB Abhydrolase_3 PF07859.8 EGO20640.1 - 7.4e-24 84.4 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO20640.1 - 3e-09 36.0 0.0 2.2e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EGO20640.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO20640.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Alpha_kinase PF02816.13 EGO20643.1 - 2.2e-05 24.1 0.2 5.9e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Alpha-kinase family zf-UDP PF14569.1 EGO20643.1 - 0.048 13.4 1.7 0.13 12.0 1.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Abhydrolase_3 PF07859.8 EGO20645.1 - 9.8e-24 84.1 0.0 1.5e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO20645.1 - 2.6e-09 36.2 0.0 1.9e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EGO20645.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO20645.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0029 PF01205.14 EGO20646.1 - 4e-24 84.4 0.0 5.4e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DNA_pol_B PF00136.16 EGO20647.1 - 2.4e-111 372.8 0.0 5.7e-111 371.5 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EGO20647.1 - 8.7e-50 168.6 0.0 1.4e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EGO20647.1 - 5e-24 84.7 0.0 8.8e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EGO20647.1 - 6.8e-14 51.4 7.3 6.8e-14 51.4 5.0 2.9 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal YL1 PF05764.8 EGO20647.1 - 0.024 14.2 6.2 0.065 12.8 4.3 1.7 1 0 0 1 1 1 0 YL1 nuclear protein Flavin_Reduct PF01613.13 EGO20648.1 - 2.6e-16 59.8 2.8 3.8e-16 59.3 1.9 1.2 1 0 0 1 1 1 1 Flavin reductase like domain zf-DNL PF05180.7 EGO20649.1 - 3.1e-27 94.0 0.1 3.9e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 DNL zinc finger FAD_binding_3 PF01494.14 EGO20650.1 - 5e-44 150.7 0.3 3e-43 148.2 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGO20650.1 - 1.2e-08 34.4 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EGO20650.1 - 1.3e-08 34.1 0.6 0.0015 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO20650.1 - 3e-08 33.9 0.1 9.5e-08 32.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO20650.1 - 0.00012 20.9 0.4 0.005 15.5 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGO20650.1 - 0.00055 19.8 0.1 0.0017 18.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO20650.1 - 0.0014 17.2 0.8 0.66 8.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EGO20650.1 - 0.0018 18.6 1.0 0.84 10.0 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGO20650.1 - 0.0032 16.3 0.1 0.0067 15.2 0.1 1.5 1 1 0 1 1 1 1 Squalene epoxidase ThiF PF00899.16 EGO20650.1 - 0.0055 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 EGO20650.1 - 0.0056 16.4 0.2 0.16 11.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EGO20650.1 - 0.0098 16.0 0.0 0.074 13.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EGO20650.1 - 0.0099 14.8 0.1 2.6 6.8 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO20650.1 - 0.085 12.8 0.2 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO20650.1 - 0.16 11.0 0.4 0.38 9.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Glyco_transf_4 PF13439.1 EGO20651.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-CCHC PF00098.18 EGO20652.1 - 6.4e-07 28.9 2.0 1.1e-06 28.2 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EGO20653.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Imm_superinfect PF14373.1 EGO20653.1 - 0.1 12.2 0.2 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Superinfection immunity protein zf-CCHC PF00098.18 EGO20654.1 - 1.6e-08 34.0 4.7 3.5e-08 32.9 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO20654.1 - 0.025 14.2 0.4 0.051 13.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Rogdi_lz PF10259.4 EGO20654.1 - 0.034 13.2 0.1 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein FAD_binding_3 PF01494.14 EGO20655.1 - 1.6e-44 152.4 0.1 7.5e-44 150.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGO20655.1 - 1.5e-06 27.5 0.0 2.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO20655.1 - 2.3e-05 24.5 0.2 0.00013 22.0 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO20655.1 - 2.4e-05 23.4 1.1 0.13 11.1 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO20655.1 - 0.00031 20.6 0.0 0.00067 19.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO20655.1 - 0.00039 19.1 0.4 0.061 11.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EGO20655.1 - 0.0036 15.8 0.4 0.22 9.9 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein ThiF PF00899.16 EGO20655.1 - 0.0056 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family SE PF08491.5 EGO20655.1 - 0.0073 15.1 0.5 0.012 14.4 0.3 1.4 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EGO20655.1 - 0.024 14.4 0.5 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGO20655.1 - 0.031 14.6 1.2 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO20655.1 - 0.047 12.6 0.1 0.17 10.7 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO20655.1 - 0.056 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO20655.1 - 0.069 12.2 0.1 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EGO20655.1 - 0.1 11.3 0.5 0.19 10.5 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EGO20655.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EGO20657.1 - 5.5e-33 114.1 30.9 5.5e-33 114.1 21.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily YqbF PF14553.1 EGO20661.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 YqbF, hypothetical protein domain HIT PF01230.18 EGO20662.1 - 4.3e-24 84.9 0.0 6.5e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO20662.1 - 2.2e-08 34.3 0.0 3.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LRR_4 PF12799.2 EGO20663.1 - 5.7 6.6 7.4 7.3 6.3 0.1 3.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) MukB PF04310.7 EGO20664.1 - 0.048 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal LRR_4 PF12799.2 EGO20665.1 - 0.044 13.4 3.0 1.6 8.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) HAUS6_N PF14661.1 EGO20666.1 - 8.5e-09 35.1 0.1 0.00014 21.3 0.0 3.3 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 6 N-terminus HHV6-IE PF03753.8 EGO20666.1 - 0.099 10.1 2.1 0.14 9.5 1.4 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein WD40 PF00400.27 EGO20668.1 - 5e-144 463.6 57.2 1.1e-12 47.2 1.0 14.9 15 0 0 15 15 14 13 WD domain, G-beta repeat PD40 PF07676.7 EGO20668.1 - 6.7e-17 60.7 12.0 0.71 9.6 0.0 12.7 14 0 0 14 14 14 4 WD40-like Beta Propeller Repeat NACHT PF05729.7 EGO20668.1 - 6.2e-07 29.2 0.1 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain Nup160 PF11715.3 EGO20668.1 - 2.3e-05 22.7 9.6 0.97 7.4 0.0 7.9 5 3 0 9 9 9 1 Nucleoporin Nup120/160 AAA_16 PF13191.1 EGO20668.1 - 7e-05 22.8 0.1 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.1 EGO20668.1 - 0.00026 20.1 18.0 9.4 5.2 0.0 9.9 3 3 8 11 11 11 1 Neuroblastoma-amplified sequence, N terminal Robl_LC7 PF03259.12 EGO20668.1 - 0.003 17.0 0.1 26 4.4 0.0 5.6 6 0 0 6 6 5 0 Roadblock/LC7 domain FlgD_ig PF13860.1 EGO20668.1 - 0.0096 15.6 0.0 1.7 8.4 0.0 3.5 4 0 0 4 4 3 1 FlgD Ig-like domain DUF3312 PF11768.3 EGO20668.1 - 0.027 12.7 0.0 4.2 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) DUF2075 PF09848.4 EGO20668.1 - 0.031 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGO20668.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGO20668.1 - 0.06 12.1 0.0 0.25 10.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.15 EGO20668.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EGO20668.1 - 0.13 12.4 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EGO20668.1 - 0.47 9.5 0.0 0.84 8.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Retrotrans_gag PF03732.12 EGO20669.1 - 8.3e-10 38.6 2.0 1.8e-09 37.5 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein BMFP PF04380.8 EGO20669.1 - 0.14 12.3 2.3 3.4 7.8 0.3 3.1 4 0 0 4 4 4 0 Membrane fusogenic activity FlxA PF14282.1 EGO20670.1 - 0.13 12.1 0.3 0.21 11.5 0.2 1.4 1 1 0 1 1 1 0 FlxA-like protein DUF3251 PF11622.3 EGO20673.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) RicinB_lectin_2 PF14200.1 EGO20674.1 - 7.1e-15 55.2 3.4 1.5e-09 38.1 1.9 3.6 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EGO20674.1 - 0.0022 18.0 3.5 0.013 15.5 1.2 2.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EGO20678.1 - 7.6e-19 68.0 1.6 1.4e-16 60.7 0.9 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EGO20678.1 - 8.6e-05 22.5 5.7 0.0015 18.5 0.3 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EGO20680.1 - 2e-07 31.3 0.0 3.2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Gal4_dimer PF03902.8 EGO20683.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1768 PF08719.6 EGO20684.1 - 2.4e-18 66.3 0.0 2.7e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 EGO20685.1 - 2.2e-05 24.2 0.1 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF4219 PF13961.1 EGO20686.1 - 0.12 11.8 0.6 0.2 11.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_3 PF13917.1 EGO20688.1 - 1.8e-06 27.5 1.4 3.2e-06 26.7 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO20688.1 - 4.9e-05 23.0 5.5 8.1e-05 22.3 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO20688.1 - 0.29 10.6 3.6 0.53 9.8 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Cerato-platanin PF07249.7 EGO20689.1 - 4.3e-06 26.7 0.0 5.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Cerato-platanin DUF3251 PF11622.3 EGO20690.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) PARP PF00644.15 EGO20693.1 - 2.7e-14 53.0 3.5 1.5e-11 44.0 0.8 3.2 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain RPAP2_Rtr1 PF04181.8 EGO20693.1 - 5.2 7.2 12.5 3.5 7.7 0.8 3.2 3 0 0 3 3 3 0 Rtr1/RPAP2 family PARP PF00644.15 EGO20694.1 - 3.6e-20 72.2 6.2 5.5e-09 35.7 0.0 4.2 2 2 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain YyzF PF14116.1 EGO20694.1 - 1.1 9.2 6.1 5.3 7.0 0.0 4.3 4 0 0 4 4 4 0 YyzF-like protein zf-FCS PF06467.9 EGO20694.1 - 4.2 7.0 17.8 0.2 11.2 2.9 3.6 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif TFIIA PF03153.8 EGO20695.1 - 6.2 6.6 6.6 7.3 6.3 4.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PARP PF00644.15 EGO20696.1 - 2.4e-13 49.9 4.1 1.7e-08 34.1 0.0 3.8 3 1 1 4 4 4 3 Poly(ADP-ribose) polymerase catalytic domain Perm-CXXC PF15629.1 EGO20696.1 - 0.058 13.4 1.3 0.058 13.4 0.9 2.0 2 0 0 2 2 2 0 Permuted single zf-CXXC unit PARP PF00644.15 EGO20697.1 - 4.9e-09 35.9 0.6 2.5e-06 27.0 0.0 3.4 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain DHQS PF01959.11 EGO20697.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) zf-FCS PF06467.9 EGO20697.1 - 0.028 14.0 1.7 0.028 14.0 1.2 4.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Fer4_11 PF13247.1 EGO20697.1 - 7.7 6.4 18.4 4.6 7.1 0.8 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain PARP PF00644.15 EGO20698.1 - 1.2e-13 50.9 0.0 1.4e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.9 EGO20698.1 - 0.0093 15.5 8.9 0.18 11.5 0.5 3.0 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif Fer4_11 PF13247.1 EGO20698.1 - 0.17 11.8 6.3 1.2 9.0 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain PARP PF00644.15 EGO20699.1 - 1.8e-12 47.1 0.4 7.3e-10 38.6 0.1 3.1 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF329 PF03884.9 EGO20699.1 - 0.054 13.0 38.9 0.19 11.3 1.0 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF329) PARP PF00644.15 EGO20700.1 - 1.6e-11 44.0 1.1 9.2e-09 35.0 0.1 2.8 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 EGO20701.1 - 2.2e-34 118.4 0.0 3e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Alpha_kinase PF02816.13 EGO20702.1 - 1.1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.11 EGO20704.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1768 PF08719.6 EGO20705.1 - 2.1e-68 228.9 0.0 4.1e-33 114.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1768) Pox_E8 PF03394.8 EGO20705.1 - 0.041 13.2 0.0 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus E8 protein Complex1_LYR PF05347.10 EGO20705.1 - 0.071 12.9 0.4 18 5.2 0.0 2.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF3259 PF11652.3 EGO20705.1 - 0.15 12.2 2.1 7.1 6.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3259) PARP PF00644.15 EGO20706.1 - 7.1e-09 35.3 0.1 4.2e-07 29.5 0.0 2.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Fer4_11 PF13247.1 EGO20706.1 - 0.13 12.1 16.4 1.6 8.6 0.6 3.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain YyzF PF14116.1 EGO20706.1 - 0.64 10.0 10.7 5.6 7.0 0.3 3.6 3 0 0 3 3 3 0 YyzF-like protein zf-FCS PF06467.9 EGO20706.1 - 2.2 7.9 21.4 0.38 10.4 0.5 4.5 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif APH PF01636.18 EGO20707.1 - 2.9e-06 27.2 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGO20707.1 - 1e-05 24.8 0.0 4e-05 22.8 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain RIO1 PF01163.17 EGO20707.1 - 0.00075 18.8 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EGO20707.1 - 0.0076 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.6 EGO20707.1 - 0.0082 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 EGO20707.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CagE_TrbE_VirB PF03135.9 EGO20709.1 - 0.1 12.3 0.1 6 6.5 0.1 2.2 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system PARP PF00644.15 EGO20711.1 - 3e-08 33.3 0.9 1.6e-07 30.9 0.6 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Perm-CXXC PF15629.1 EGO20711.1 - 3.5 7.7 13.0 0.34 10.9 4.7 2.6 2 0 0 2 2 2 0 Permuted single zf-CXXC unit Ecl1 PF12855.2 EGO20712.1 - 0.016 14.5 9.6 0.33 10.2 0.4 4.1 4 0 0 4 4 4 0 Life-span regulatory factor zf-MYND PF01753.13 EGO20712.1 - 2.6 8.0 22.3 4.3 7.2 1.3 4.3 3 1 0 3 3 3 0 MYND finger Metallothio_Pro PF02069.11 EGO20712.1 - 5.1 7.0 15.1 7.5 6.4 0.3 4.0 3 1 0 3 3 3 0 Prokaryotic metallothionein DUF1768 PF08719.6 EGO20713.1 - 2.7e-34 118.1 0.0 4.2e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PROL5-SMR PF15621.1 EGO20713.1 - 0.043 14.2 0.9 0.07 13.5 0.6 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF1768 PF08719.6 EGO20714.1 - 2e-31 108.8 0.0 2.9e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) zf-UBR PF02207.15 EGO20714.1 - 2.3 7.9 24.7 4.8 6.9 3.3 2.9 1 1 2 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Fer4_11 PF13247.1 EGO20714.1 - 7 6.6 20.0 2.7 7.9 1.5 3.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain WD40 PF00400.27 EGO20716.1 - 4.1e-15 55.0 6.0 8.8e-06 25.4 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO20716.1 - 0.047 13.4 0.0 3.3 7.3 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PX PF00787.19 EGO20717.1 - 2.9e-13 49.6 0.0 6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Abhydrolase_1 PF00561.15 EGO20718.1 - 3e-11 43.3 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EGO20718.1 - 1.1e-08 34.8 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EGO20718.1 - 4e-08 33.4 0.0 6.3e-07 29.5 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO20718.1 - 0.0069 16.1 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1982 PF09326.6 EGO20719.1 - 0.0096 16.0 0.3 0.025 14.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) HNF_C PF09354.5 EGO20720.1 - 0.0079 17.3 1.8 1 10.5 0.5 2.2 1 1 1 2 2 2 2 HNF3 C-terminal domain G-alpha PF00503.15 EGO20721.1 - 1e-56 192.3 0.8 1.1e-56 192.2 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Lipocalin_7 PF14651.1 EGO20721.1 - 0.081 12.6 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family PepSY_TM_1 PF13172.1 EGO20722.1 - 4.9 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix RVP_2 PF08284.6 EGO20725.1 - 0.028 14.3 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Imm_superinfect PF14373.1 EGO20725.1 - 0.074 12.7 0.2 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Superinfection immunity protein Ribosomal_L37e PF01907.14 EGO20726.1 - 3.2e-26 90.8 13.9 5.6e-26 90.0 9.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EGO20726.1 - 0.00023 20.9 2.2 0.00036 20.2 1.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EGO20726.1 - 0.008 15.8 0.3 0.01 15.5 0.2 1.4 1 1 0 1 1 1 1 SelR domain HypA PF01155.14 EGO20726.1 - 0.07 12.8 0.9 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EGO20726.1 - 0.13 11.4 2.4 0.34 10.1 1.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGO20726.1 - 0.15 11.6 3.5 1.5 8.3 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain LIM PF00412.17 EGO20726.1 - 0.2 11.7 3.9 0.39 10.8 2.7 1.5 1 1 0 1 1 1 0 LIM domain zf-C3HC4 PF00097.20 EGO20726.1 - 0.49 10.0 5.5 0.8 9.4 3.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.9 EGO20726.1 - 0.59 10.1 4.6 1.4 8.8 0.5 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S14 PF00253.16 EGO20726.1 - 0.86 9.0 10.2 1.7 8.0 0.3 2.7 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e zf-C3HC4_2 PF13923.1 EGO20726.1 - 3.8 7.6 5.8 6.2 6.9 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GATA PF00320.22 EGO20727.1 - 2.1e-18 65.3 3.5 2.9e-18 64.8 2.4 1.2 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGO20727.1 - 0.0075 15.5 1.8 0.012 14.8 1.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding DZR PF12773.2 EGO20727.1 - 0.025 14.3 0.3 0.058 13.2 0.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.13 EGO20727.1 - 0.025 14.3 0.4 0.026 14.2 0.3 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 EGO20727.1 - 0.051 12.7 2.8 0.17 11.1 2.0 1.8 1 1 0 1 1 1 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.12 EGO20727.1 - 0.067 12.8 0.2 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.7 EGO20727.1 - 0.082 12.9 2.0 0.12 12.4 1.4 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase ADK_lid PF05191.9 EGO20727.1 - 0.12 12.0 1.1 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-FCS PF06467.9 EGO20727.1 - 0.17 11.5 1.7 0.79 9.4 0.1 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DNA_RNApol_7kD PF03604.8 EGO20727.1 - 0.19 11.1 1.5 0.27 10.7 0.2 2.0 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.4 EGO20727.1 - 0.34 10.6 1.5 9.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.6 EGO20727.1 - 0.86 9.1 3.5 3.1 7.3 0.7 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EGO20727.1 - 2.2 7.8 4.4 11 5.6 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Lge1 PF11488.3 EGO20728.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 zf-C2H2 PF00096.21 EGO20729.1 - 2.2e-11 43.3 8.6 3.6e-05 23.8 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO20729.1 - 3.4e-08 33.3 2.6 3.4e-08 33.3 1.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO20729.1 - 1e-06 28.6 11.0 0.00087 19.4 0.4 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger Fer2 PF00111.22 EGO20729.1 - 0.0051 16.5 0.4 0.009 15.7 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-C2H2_6 PF13912.1 EGO20729.1 - 0.099 12.5 0.2 0.099 12.5 0.1 2.4 4 0 0 4 4 4 0 C2H2-type zinc finger Hepcidin PF06446.7 EGO20729.1 - 2.4 8.6 7.7 4 7.9 0.5 2.8 2 0 0 2 2 2 0 Hepcidin Opi1 PF08618.5 EGO20730.1 - 1.6e-65 221.7 12.4 1.9e-57 195.1 5.8 4.5 2 1 0 3 3 3 2 Transcription factor Opi1 Perilipin PF03036.11 EGO20730.1 - 3.3e-07 29.5 1.1 8.2e-07 28.1 0.0 2.2 3 0 0 3 3 3 1 Perilipin family REF PF05755.7 EGO20730.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) p450 PF00067.17 EGO20731.1 - 2.5e-44 151.6 0.0 3.4e-44 151.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EGO20733.1 - 6e-16 58.5 0.0 8e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO20733.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20733.1 - 1.2e-09 38.7 0.0 2.9e-09 37.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO20733.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO20733.1 - 3.7e-09 36.9 0.0 6.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGO20733.1 - 2.2e-07 30.2 0.0 3.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 EGO20733.1 - 7e-07 29.6 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO20733.1 - 3.3e-06 27.1 0.0 6.5e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO20733.1 - 1e-05 24.7 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGO20733.1 - 0.0002 20.8 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGO20733.1 - 0.00053 19.1 0.0 0.00073 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TrkA_N PF02254.13 EGO20733.1 - 0.0058 16.6 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain UPF0146 PF03686.8 EGO20733.1 - 0.019 14.7 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) TPMT PF05724.6 EGO20733.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 EGO20733.1 - 0.043 12.5 0.0 0.06 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) UDPG_MGDP_dh_N PF03721.9 EGO20733.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NodS PF05401.6 EGO20733.1 - 0.074 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.13 EGO20733.1 - 0.14 11.3 0.0 11 5.2 0.0 2.6 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FmrO PF07091.6 EGO20733.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_23 PF13489.1 EGO20734.1 - 4.8e-16 58.8 0.0 6.3e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO20734.1 - 3.8e-09 36.8 0.0 7.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO20734.1 - 4.9e-09 36.5 0.0 9.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO20734.1 - 5.2e-09 35.8 0.0 7.3e-09 35.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20734.1 - 2e-08 34.7 0.0 3.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO20734.1 - 7.1e-08 32.8 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGO20734.1 - 1.4e-06 27.6 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 EGO20734.1 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGO20734.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO20734.1 - 0.00057 19.0 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO20734.1 - 0.00076 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EGO20734.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 EGO20734.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TMEM247 PF15444.1 EGO20734.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 GATA PF00320.22 EGO20738.1 - 2.3e-08 33.2 8.3 5.5e-08 32.0 5.8 1.7 1 0 0 1 1 1 1 GATA zinc finger FAD_binding_3 PF01494.14 EGO20740.1 - 1.7e-10 40.5 0.3 1.8e-09 37.1 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EGO20741.1 - 1.4e-13 50.6 3.0 0.00017 20.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EGO20741.1 - 2.3e-10 39.9 0.1 4.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO20741.1 - 8.5e-09 34.7 0.4 4.2e-07 29.1 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO20741.1 - 1.7e-07 31.3 0.1 3.1e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO20741.1 - 4.3e-07 28.7 0.0 0.00036 19.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EGO20741.1 - 1.2e-05 25.2 0.4 6e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO20741.1 - 4.6e-05 23.7 0.9 0.0078 16.6 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO20741.1 - 0.00052 19.1 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EGO20741.1 - 0.0015 17.7 0.0 0.77 8.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EGO20741.1 - 0.0095 14.8 0.0 0.24 10.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EGO20741.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EGO20741.1 - 0.013 14.6 0.1 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 EGO20741.1 - 0.031 13.6 0.3 0.05 12.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EGO20741.1 - 0.057 12.0 0.4 1 7.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thiolase_N PF00108.18 EGO20742.1 - 9.5e-80 267.3 2.4 9.5e-80 267.3 1.7 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO20742.1 - 1.2e-45 153.8 0.7 1.2e-45 153.8 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGO20742.1 - 0.00081 18.9 0.6 0.025 14.0 0.1 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGO20742.1 - 0.009 15.6 1.9 3.7 7.2 0.0 2.9 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SIR2 PF02146.12 EGO20743.1 - 1.4e-46 158.4 0.1 4.7e-45 153.4 0.0 2.5 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EGO20743.1 - 8.6e-07 28.6 1.1 2.1e-05 24.1 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF592) Histone PF00125.19 EGO20744.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO20744.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO20744.1 - 0.00065 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO20744.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGO20744.1 - 0.22 10.7 2.3 0.24 10.5 1.6 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EGO20745.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO20745.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGO20745.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGO20745.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGO20745.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGO20745.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Nucleopor_Nup85 PF07575.8 EGO20746.1 - 1.1e-59 202.1 0.0 1.2e-57 195.4 0.0 2.0 1 1 0 1 1 1 1 Nup85 Nucleoporin RhoGAP PF00620.22 EGO20748.1 - 3e-47 160.0 0.0 6.2e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGO20748.1 - 2.6e-14 53.1 4.0 1.4e-13 50.7 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Baculo_PEP_C PF04513.7 EGO20748.1 - 0.077 12.8 0.3 2.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.8 EGO20748.1 - 1.1 8.2 3.6 2 7.4 2.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein F-box-like PF12937.2 EGO20749.1 - 6.2e-10 38.6 2.2 2.8e-09 36.5 0.1 2.6 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EGO20749.1 - 0.0029 17.5 0.7 0.36 11.0 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeat F-box PF00646.28 EGO20749.1 - 0.13 11.9 3.5 0.23 11.1 0.0 2.9 3 0 0 3 3 3 0 F-box domain Histone PF00125.19 EGO20750.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO20750.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGO20750.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGO20750.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGO20750.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGO20750.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EGO20751.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO20751.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO20751.1 - 0.00065 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO20751.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGO20751.1 - 0.22 10.7 2.3 0.24 10.5 1.6 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Asp PF00026.18 EGO20752.1 - 2.4e-69 233.9 5.5 3e-69 233.6 3.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO20752.1 - 5e-06 26.5 1.7 2.1e-05 24.5 1.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Methyltransf_16 PF10294.4 EGO20753.1 - 6.1e-20 71.3 0.0 1.2e-19 70.4 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EGO20753.1 - 0.00019 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EGO20753.1 - 0.00048 19.8 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20753.1 - 0.0066 17.0 0.0 0.017 15.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EGO20753.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EGO20754.1 - 3e-27 95.2 0.0 4.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGO20754.1 - 0.00014 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rhomboid PF01694.17 EGO20755.1 - 2.1e-14 53.7 17.5 1.5e-13 50.9 12.1 2.3 1 1 0 1 1 1 1 Rhomboid family DUF457 PF04307.9 EGO20755.1 - 1.8 7.8 9.2 0.93 8.8 4.1 2.2 2 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Pkinase PF00069.20 EGO20756.1 - 0.00015 21.0 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGO20756.1 - 0.00087 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGO20756.1 - 0.0027 17.5 0.4 0.053 13.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-CCHC PF00098.18 EGO20758.1 - 1.6e-08 34.0 2.8 2.8e-08 33.3 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO20758.1 - 6.8e-07 29.2 3.9 5.5e-06 26.3 2.7 2.4 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO20758.1 - 7.2 6.4 7.9 1.2 8.9 2.0 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF4586 PF15239.1 EGO20759.1 - 0.048 13.1 0.2 0.051 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) RE_ApaLI PF09499.5 EGO20759.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease p47_phox_C PF08944.6 EGO20763.1 - 0.0059 16.7 0.2 0.0088 16.2 0.2 1.3 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain zf-CCHC_3 PF13917.1 EGO20765.1 - 0.00046 19.8 4.1 0.001 18.7 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO20765.1 - 0.00051 19.8 6.4 0.0011 18.7 4.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO20766.1 - 1.1e-09 38.1 1.6 3.3e-09 36.6 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20766.1 - 2.9e-08 33.2 5.1 5.3e-08 32.4 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO20766.1 - 5.3 6.8 8.8 0.25 11.0 1.9 1.9 2 0 0 2 2 2 0 Zinc knuckle Calpain_inhib PF00748.14 EGO20767.1 - 0.037 14.3 0.5 0.098 12.9 0.4 1.6 1 0 0 1 1 1 0 Calpain inhibitor Nuc_rec_co-act PF08815.5 EGO20767.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear receptor coactivator Nnf1 PF03980.9 EGO20768.1 - 3.2e-11 43.1 1.4 5.3e-11 42.4 0.3 1.7 1 1 1 2 2 2 1 Nnf1 Mod_r PF07200.8 EGO20768.1 - 0.0049 16.7 1.0 0.0085 16.0 0.7 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein NTR2 PF15458.1 EGO20768.1 - 0.013 14.7 1.9 0.018 14.2 1.2 1.3 1 1 0 1 1 1 0 Nineteen complex-related protein 2 Macoilin PF09726.4 EGO20768.1 - 0.015 13.5 1.4 0.017 13.4 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein CCDC14 PF15254.1 EGO20768.1 - 0.034 12.5 0.8 0.057 11.8 0.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 HALZ PF02183.13 EGO20768.1 - 0.058 13.1 1.2 0.12 12.1 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper GrpE PF01025.14 EGO20768.1 - 0.48 9.9 4.5 1 8.8 3.1 1.6 1 1 0 1 1 1 0 GrpE TSC22 PF01166.13 EGO20768.1 - 1 9.3 4.3 1.5 8.8 0.5 2.5 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF2921 PF11145.3 EGO20769.1 - 0.0013 16.5 0.6 0.002 15.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-rbx1 PF12678.2 EGO20769.1 - 0.0022 18.0 1.4 0.11 12.5 0.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGO20769.1 - 0.015 15.1 1.6 0.015 15.1 1.1 2.9 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 EGO20769.1 - 0.59 9.8 4.5 1.9 8.2 0.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO20769.1 - 1.5 8.5 3.9 22 4.7 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 EGO20771.1 - 5.6e-07 29.6 0.0 9.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EGO20771.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4541 PF15074.1 EGO20772.1 - 0.016 15.7 0.6 0.038 14.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) zf-CCHC_4 PF14392.1 EGO20773.1 - 2.7 7.7 9.0 0.064 12.9 1.6 1.7 2 0 0 2 2 2 0 Zinc knuckle adh_short PF00106.20 EGO20774.1 - 2.2e-09 37.4 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20774.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO20774.1 - 0.048 13.4 0.0 0.14 11.8 0.0 1.8 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase SNAPc19 PF15497.1 EGO20775.1 - 0.095 12.9 0.6 0.098 12.8 0.4 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF3441 PF11923.3 EGO20776.1 - 0.15 11.6 0.1 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) YL1 PF05764.8 EGO20778.1 - 0.0019 17.8 15.8 0.0032 17.0 11.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein zf-CCHC PF00098.18 EGO20778.1 - 0.0066 16.3 2.6 0.017 15.0 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Nop53 PF07767.6 EGO20778.1 - 0.0088 15.0 10.2 0.015 14.3 7.0 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.7 EGO20778.1 - 0.058 13.0 12.7 0.12 12.1 8.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RepB-RCR_reg PF10723.4 EGO20778.1 - 0.066 12.9 2.1 0.15 11.7 1.5 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB zf-CCHC_4 PF14392.1 EGO20778.1 - 0.09 12.4 5.1 0.16 11.6 1.7 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EGO20778.1 - 0.09 12.2 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CDC45 PF02724.9 EGO20778.1 - 0.31 9.0 13.3 0.44 8.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF106 PF01956.11 EGO20778.1 - 1.5 8.3 4.0 0.45 10.0 0.6 1.7 2 0 0 2 2 2 0 Integral membrane protein DUF106 BUD22 PF09073.5 EGO20778.1 - 3.3 6.6 20.0 6 5.8 13.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO20778.1 - 3.6 5.3 18.0 1.3 6.8 10.6 1.5 2 0 0 2 2 2 0 Nop14-like family MULE PF10551.4 EGO20781.1 - 0.0003 20.8 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Peptidase_S30 PF01577.11 EGO20781.1 - 0.0022 17.4 0.7 0.015 14.6 0.0 2.4 3 0 0 3 3 3 1 Potyvirus P1 protease Pkinase PF00069.20 EGO20783.1 - 0.00014 21.0 0.0 0.00015 21.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO20783.1 - 0.0075 16.0 0.1 0.0089 15.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO20783.1 - 0.009 15.3 0.0 0.0091 15.3 0.0 1.0 1 0 0 1 1 1 1 RIO1 family Rhomboid PF01694.17 EGO20784.1 - 7.7e-08 32.4 3.0 8.3e-08 32.3 2.1 1.1 1 0 0 1 1 1 1 Rhomboid family Retrotrans_gag PF03732.12 EGO20786.1 - 1.7e-05 24.8 0.5 4.4e-05 23.4 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20786.1 - 0.00051 19.8 4.5 0.0011 18.8 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EGO20786.1 - 0.00099 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO20786.1 - 0.057 13.9 0.1 0.64 10.5 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.12 EGO20787.1 - 1.7e-06 27.9 1.7 2.3e-06 27.5 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-C4pol PF14260.1 EGO20789.1 - 0.07 13.1 2.2 0.15 12.0 1.5 1.5 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF4042 PF13251.1 EGO20790.1 - 0.075 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Pkinase PF00069.20 EGO20791.1 - 0.00065 18.9 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGO20791.1 - 0.005 16.2 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGO20791.1 - 0.093 12.4 2.4 0.24 11.0 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Retrotrans_gag PF03732.12 EGO20793.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20793.1 - 0.059 13.3 0.5 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 EGO20795.1 - 1.8e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO20795.1 - 0.00018 21.9 0.0 0.00025 21.4 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO20795.1 - 0.004 17.0 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Siva PF05458.7 EGO20795.1 - 0.051 13.1 0.0 0.096 12.2 0.0 1.4 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Retrotrans_gag PF03732.12 EGO20796.1 - 6.1e-08 32.6 0.1 1.6e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Nnf1 PF03980.9 EGO20799.1 - 3.2e-11 43.1 1.4 5.3e-11 42.4 0.3 1.7 1 1 1 2 2 2 1 Nnf1 Mod_r PF07200.8 EGO20799.1 - 0.0049 16.7 1.0 0.0085 16.0 0.7 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein NTR2 PF15458.1 EGO20799.1 - 0.013 14.7 1.9 0.018 14.2 1.2 1.3 1 1 0 1 1 1 0 Nineteen complex-related protein 2 Macoilin PF09726.4 EGO20799.1 - 0.015 13.5 1.4 0.017 13.4 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein CCDC14 PF15254.1 EGO20799.1 - 0.034 12.5 0.8 0.057 11.8 0.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 HALZ PF02183.13 EGO20799.1 - 0.058 13.1 1.2 0.12 12.1 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper GrpE PF01025.14 EGO20799.1 - 0.48 9.9 4.5 1 8.8 3.1 1.6 1 1 0 1 1 1 0 GrpE TSC22 PF01166.13 EGO20799.1 - 1 9.3 4.3 1.5 8.8 0.5 2.5 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF2921 PF11145.3 EGO20800.1 - 0.0011 16.7 0.5 0.0017 16.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-rbx1 PF12678.2 EGO20800.1 - 0.0022 18.0 1.4 0.11 12.5 0.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGO20800.1 - 0.015 15.1 1.6 0.015 15.1 1.1 2.9 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 EGO20800.1 - 0.59 9.8 4.5 1.9 8.2 0.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO20800.1 - 1.5 8.5 3.9 22 4.7 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 EGO20802.1 - 8.4e-07 29.0 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EGO20802.1 - 0.027 13.9 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SNAPc19 PF15497.1 EGO20803.1 - 0.045 13.9 0.6 0.045 13.9 0.4 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Transposase_21 PF02992.9 EGO20804.1 - 8.2e-11 41.4 0.1 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Pkinase PF00069.20 EGO20806.1 - 0.00011 21.4 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGO20806.1 - 0.00086 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGO20806.1 - 0.0026 17.5 0.4 0.053 13.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Retrotrans_gag PF03732.12 EGO20807.1 - 4.7e-06 26.5 1.1 8.6e-06 25.7 0.6 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein Pkinase PF00069.20 EGO20811.1 - 0.00015 20.9 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO20811.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGO20811.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family UBN2_2 PF14227.1 EGO20812.1 - 0.0022 17.5 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGO20812.1 - 0.022 14.2 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO20812.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) adh_short PF00106.20 EGO20814.1 - 4.2e-18 65.8 0.1 6.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20814.1 - 1.2e-07 31.5 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO20814.1 - 6.9e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EGO20814.1 - 6.5e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO20814.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO20814.1 - 0.017 14.3 0.1 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 EGO20814.1 - 0.13 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-rbx1 PF12678.2 EGO20817.1 - 6.8e-09 35.7 0.7 1.4e-08 34.7 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGO20817.1 - 2.5e-08 33.5 8.2 1.9e-07 30.8 5.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO20817.1 - 6.5e-06 25.7 2.8 1.2e-05 24.8 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO20817.1 - 1.9e-05 24.2 3.0 4.9e-05 22.8 2.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO20817.1 - 6.6e-05 22.5 2.1 0.00014 21.5 1.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO20817.1 - 0.00018 21.4 1.9 0.00018 21.4 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO20817.1 - 0.0013 18.5 0.5 0.0031 17.3 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EGO20817.1 - 0.0024 15.7 0.3 0.0036 15.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-RING_4 PF14570.1 EGO20817.1 - 0.11 12.0 1.0 0.4 10.3 0.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EGO20817.1 - 0.24 10.9 2.9 0.52 9.8 2.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger RINGv PF12906.2 EGO20817.1 - 3.9 7.5 7.3 0.56 10.2 2.0 1.8 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EGO20817.1 - 6.7 6.7 7.1 48 4.0 4.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Nnf1 PF03980.9 EGO20818.1 - 2.8e-11 43.3 1.6 4.2e-11 42.7 0.4 1.7 1 1 1 2 2 2 1 Nnf1 Mod_r PF07200.8 EGO20818.1 - 0.003 17.5 0.7 0.0051 16.7 0.5 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Macoilin PF09726.4 EGO20818.1 - 0.044 12.0 1.4 0.049 11.9 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF904 PF06005.7 EGO20818.1 - 0.076 13.3 2.0 0.15 12.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EGO20818.1 - 0.58 10.1 3.7 1.4 8.9 0.5 2.5 3 0 0 3 3 3 0 TSC-22/dip/bun family ISN1 PF06437.6 EGO20819.1 - 0.065 11.9 0.0 0.087 11.5 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Neuro_bHLH PF12533.3 EGO20819.1 - 1.3 9.8 15.6 3.9 8.2 10.8 1.8 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor Retrotrans_gag PF03732.12 EGO20820.1 - 9.6e-09 35.2 0.4 9.6e-09 35.2 0.3 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20820.1 - 3.2e-08 33.1 5.1 5.8e-08 32.2 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO20820.1 - 0.1 12.3 2.8 0.29 10.8 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle MULE PF10551.4 EGO20822.1 - 0.0003 20.9 0.1 0.00077 19.5 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Peptidase_S30 PF01577.11 EGO20822.1 - 0.0021 17.4 0.0 0.0084 15.5 0.0 1.9 2 0 0 2 2 2 1 Potyvirus P1 protease Pkinase PF00069.20 EGO20823.1 - 0.0004 19.6 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGO20823.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGO20823.1 - 0.015 15.0 0.4 0.15 11.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Retrotrans_gag PF03732.12 EGO20824.1 - 7.1e-05 22.8 5.1 0.00021 21.3 1.0 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20824.1 - 0.00015 21.4 3.2 0.00028 20.6 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO20825.1 - 2.8e-05 24.1 0.4 2.8e-05 24.1 0.3 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20825.1 - 0.084 12.8 1.0 0.89 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.1 EGO20826.1 - 2.5e-06 27.2 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO20826.1 - 3.7e-06 27.3 0.0 4.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO20826.1 - 9.6e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Myb_DNA-bind_4 PF13837.1 EGO20828.1 - 2e-06 27.8 0.0 2.9e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EGO20828.1 - 0.083 13.5 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3886 PF13025.1 EGO20831.1 - 2.4 8.2 7.0 0.4 10.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Nnf1 PF03980.9 EGO20832.1 - 2.4e-11 43.6 1.5 3.6e-11 43.0 0.3 1.7 1 1 1 2 2 2 1 Nnf1 Mod_r PF07200.8 EGO20832.1 - 0.0029 17.5 0.7 0.0051 16.7 0.5 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Macoilin PF09726.4 EGO20832.1 - 0.047 11.9 1.5 0.053 11.8 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF904 PF06005.7 EGO20832.1 - 0.077 13.3 2.0 0.15 12.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EGO20832.1 - 0.58 10.1 3.7 1.4 8.9 0.5 2.5 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF3270 PF11674.3 EGO20833.1 - 3.5 7.7 4.9 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) UBN2_2 PF14227.1 EGO20835.1 - 1.6e-06 27.7 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO20835.1 - 0.0021 17.8 0.1 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MULE PF10551.4 EGO20838.1 - 0.00019 21.5 0.1 0.00045 20.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Pkinase PF00069.20 EGO20839.1 - 0.0038 16.4 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGO20839.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Rhomboid PF01694.17 EGO20840.1 - 0.003 17.5 1.4 0.0039 17.2 1.0 1.2 1 0 0 1 1 1 1 Rhomboid family DUF4219 PF13961.1 EGO20843.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Gb3_synth PF04572.7 EGO20844.1 - 0.052 13.2 0.2 0.081 12.6 0.1 1.3 1 1 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Retrotrans_gag PF03732.12 EGO20847.1 - 1.7e-05 24.8 1.7 7e-05 22.8 1.2 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20847.1 - 6.7e-05 22.6 5.8 0.00016 21.4 4.0 1.7 1 0 0 1 1 1 1 Zinc knuckle VanY PF02557.12 EGO20847.1 - 0.08 12.7 1.3 0.18 11.6 0.3 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase gag_pre-integrs PF13976.1 EGO20848.1 - 7.1e-09 35.1 0.6 1.1e-08 34.5 0.4 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.12 EGO20849.1 - 2e-07 30.9 0.1 2e-07 30.9 0.1 2.3 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO20849.1 - 7.5e-07 28.7 4.3 1.4e-06 27.9 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO20849.1 - 0.033 13.9 2.4 0.033 13.9 1.6 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2 PF09337.5 EGO20850.1 - 0.0024 17.2 2.7 0.0033 16.7 1.8 1.2 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger gag_pre-integrs PF13976.1 EGO20850.1 - 4.1 7.1 8.5 0.4 10.3 2.6 1.7 2 0 0 2 2 2 0 GAG-pre-integrase domain Pkinase PF00069.20 EGO20855.1 - 0.0052 15.9 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGO20855.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Zn_Tnp_IS91 PF14319.1 EGO20857.1 - 0.4 10.1 4.8 0.7 9.4 3.3 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_3 PF13917.1 EGO20857.1 - 0.41 10.4 6.6 0.91 9.3 4.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-ribbon_3 PF13248.1 EGO20857.1 - 9.1 5.6 10.6 2.8 7.2 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain PDH PF02153.12 EGO20863.1 - 4.6e-12 45.3 0.0 6.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EGO20863.1 - 2.7e-05 24.0 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGO20863.1 - 0.00045 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EGO20863.1 - 0.039 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 EGO20863.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGO20863.1 - 0.14 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ArgJ PF01960.13 EGO20864.1 - 1.8e-146 487.4 1.2 2.1e-146 487.3 0.8 1.0 1 0 0 1 1 1 1 ArgJ family ATP-grasp PF02222.17 EGO20864.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_L35Ae PF01247.13 EGO20865.1 - 7.2e-43 144.2 0.6 8e-43 144.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EGO20865.1 - 0.0016 18.3 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain adh_short_C2 PF13561.1 EGO20866.1 - 1.3e-26 93.8 0.0 1.7e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO20866.1 - 1.7e-24 86.6 0.4 2.9e-24 85.8 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO20866.1 - 1.6e-11 44.1 0.1 2.8e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Maf PF02545.9 EGO20867.1 - 8.3e-33 113.1 0.0 2.8e-15 55.9 0.0 2.3 2 1 0 2 2 2 2 Maf-like protein WD40 PF00400.27 EGO20868.1 - 3.6e-20 71.0 4.5 6.5e-07 29.0 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO20868.1 - 0.0077 15.9 0.2 0.14 11.8 0.0 2.6 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Exo_endo_phos PF03372.18 EGO20871.1 - 6.2e-14 52.5 0.0 1.1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGO20871.1 - 2.4e-09 36.8 0.1 4.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EGO20871.1 - 2.1e-08 33.9 2.7 8.4e-06 25.6 0.1 2.5 2 0 0 2 2 2 2 GRF zinc finger Phostensin PF13914.1 EGO20871.1 - 0.22 11.6 7.5 0.75 9.9 5.2 1.9 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Kinesin PF00225.18 EGO20872.1 - 3.7e-105 351.3 2.2 6e-105 350.6 1.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Reo_sigmaC PF04582.7 EGO20872.1 - 0.0083 15.3 4.5 0.0083 15.3 3.1 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein DUF972 PF06156.8 EGO20872.1 - 0.012 15.9 7.6 7.8 6.8 0.0 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EGO20872.1 - 0.025 13.8 2.4 0.051 12.8 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 EGO20872.1 - 0.038 13.7 7.5 0.13 12.0 5.2 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EGO20872.1 - 0.052 12.4 7.6 0.017 14.0 2.6 2.1 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 EGO20872.1 - 0.066 13.0 6.2 0.22 11.3 4.3 1.8 1 0 0 1 1 1 0 Tropomyosin like Arch_ATPase PF01637.13 EGO20872.1 - 0.071 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase Tropomyosin PF00261.15 EGO20872.1 - 0.13 11.3 5.1 0.19 10.8 3.0 1.7 1 1 0 1 1 1 0 Tropomyosin NPV_P10 PF05531.7 EGO20872.1 - 0.24 11.6 4.8 10 6.4 0.5 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 EGO20872.1 - 0.3 11.1 13.5 0.18 11.8 2.5 3.1 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.1 EGO20872.1 - 0.49 10.3 11.4 3.3 7.6 6.3 3.0 2 1 1 3 3 3 0 FlxA-like protein IncA PF04156.9 EGO20872.1 - 0.78 9.3 10.5 6.1 6.4 7.3 2.2 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 EGO20872.1 - 0.93 8.0 7.0 1.7 7.2 4.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.7 EGO20872.1 - 1 9.2 11.6 13 5.8 0.2 4.3 2 2 2 4 4 4 0 Viral A-type inclusion protein repeat DUF1664 PF07889.7 EGO20872.1 - 1 9.1 4.3 1.3 8.8 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 EGO20872.1 - 2.6 7.6 6.4 3 7.4 2.9 2.0 1 1 1 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 EGO20872.1 - 2.7 7.8 9.5 0.88 9.4 1.2 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DAP3 PF10236.4 EGO20873.1 - 5.3e-71 239.0 0.0 6.5e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EGO20873.1 - 7.5e-07 29.3 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO20873.1 - 1.3e-06 28.0 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EGO20873.1 - 0.00096 18.6 0.2 0.0036 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGO20873.1 - 0.0056 16.4 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EGO20873.1 - 0.0065 16.6 0.0 0.07 13.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO20873.1 - 0.037 13.4 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.1 EGO20873.1 - 0.039 13.8 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGO20873.1 - 0.04 13.4 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EGO20873.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RHSP PF07999.6 EGO20873.1 - 0.097 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein AAA_30 PF13604.1 EGO20873.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain GATA PF00320.22 EGO20875.1 - 4.4e-14 51.5 2.7 9.5e-14 50.4 1.8 1.6 1 0 0 1 1 1 1 GATA zinc finger Sds3 PF08598.6 EGO20876.1 - 1.4e-05 24.7 2.3 1.9e-05 24.2 1.6 1.3 1 1 0 1 1 1 1 Sds3-like YihI PF04220.7 EGO20877.1 - 1.1 8.5 4.6 2.3 7.5 3.2 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) Gemini_AL1 PF00799.15 EGO20879.1 - 1.2e-14 54.0 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain Gemini_AL1_M PF08283.6 EGO20879.1 - 6.1e-13 48.5 0.6 1.2e-12 47.6 0.4 1.5 1 0 0 1 1 1 1 Geminivirus rep protein central domain Exo_endo_phos PF03372.18 EGO20880.1 - 5.6e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGO20880.1 - 3.3e-05 23.4 0.0 0.00066 19.2 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Retrotrans_gag PF03732.12 EGO20882.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein gag-asp_proteas PF13975.1 EGO20883.1 - 0.00091 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO20883.1 - 0.051 13.5 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO20883.1 - 0.058 13.9 0.0 0.065 13.7 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease SprB PF13573.1 EGO20883.1 - 0.46 10.1 1.8 2 8.0 1.3 1.9 1 1 0 1 1 1 0 SprB repeat zf-CCHC PF00098.18 EGO20884.1 - 3.4e-07 29.8 2.2 6.5e-07 28.9 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO20884.1 - 7e-05 22.8 0.1 7e-05 22.8 0.1 2.8 2 1 0 3 3 3 1 Retrotransposon gag protein Utp21 PF04192.7 EGO20885.1 - 2.1e-63 213.6 0.1 3.2e-63 213.0 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EGO20885.1 - 5.6e-17 60.9 17.6 6.3e-06 25.8 0.0 9.1 10 0 0 10 10 10 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO20885.1 - 9.9e-05 21.2 3.1 0.028 13.1 0.2 4.2 3 1 1 4 4 4 1 Nup133 N terminal like Sfi1 PF08457.5 EGO20886.1 - 8.4e-31 107.0 100.1 6.1e-21 74.4 30.6 4.7 1 1 4 5 5 5 5 Sfi1 spindle body protein DUF4578 PF15147.1 EGO20886.1 - 0.24 11.7 8.6 0.14 12.5 0.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4578) PIG-Y PF15159.1 EGO20887.1 - 2.3e-07 30.9 5.3 2.7e-07 30.6 3.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PSI_PsaF PF02507.10 EGO20887.1 - 0.14 11.7 0.4 0.15 11.5 0.3 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Adenylsucc_synt PF00709.16 EGO20889.1 - 0.0039 15.8 0.0 0.0047 15.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Herpes_UL6 PF01763.11 EGO20889.1 - 0.023 12.8 0.0 0.025 12.7 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like XRCC4 PF06632.7 EGO20889.1 - 0.028 13.2 0.2 0.034 13.0 0.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF2681 PF10883.3 EGO20889.1 - 0.032 14.4 1.0 0.054 13.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) HALZ PF02183.13 EGO20889.1 - 0.059 13.0 0.7 0.098 12.3 0.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DIOX_N PF14226.1 EGO20889.1 - 0.062 13.8 0.2 0.099 13.1 0.2 1.3 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF904 PF06005.7 EGO20889.1 - 0.15 12.3 2.5 0.22 11.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CAF-1_p150 PF11600.3 EGO20889.1 - 6.8 5.9 13.6 87 2.3 9.4 2.0 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ox_reductase_C PF08635.5 EGO20890.1 - 2.1e-71 237.9 0.2 3.1e-71 237.3 0.2 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EGO20890.1 - 1.9e-22 80.0 0.0 4.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO20890.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EGO20891.1 - 1e-19 71.2 0.1 1.7e-19 70.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DcpS_C PF11969.3 EGO20892.1 - 8.9e-14 51.7 0.1 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGO20892.1 - 3.1e-11 43.6 0.0 6.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 HIT domain zf-C2H2_2 PF12756.2 EGO20892.1 - 0.019 15.1 1.1 0.048 13.7 0.5 1.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SRP14 PF02290.10 EGO20892.1 - 0.055 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Ribosomal_S21e PF01249.13 EGO20893.1 - 9.9e-37 124.7 0.1 1.1e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e RBFA PF02033.13 EGO20893.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosome-binding factor A RabGAP-TBC PF00566.13 EGO20894.1 - 8.2e-42 143.1 7.3 6.7e-40 136.8 5.1 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EGO20894.1 - 5e-08 32.4 0.1 0.042 13.1 0.0 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF3548) PPP4R2 PF09184.6 EGO20896.1 - 1.2e-22 80.8 0.0 1.9e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 PPP4R2 SUI1 PF01253.17 EGO20897.1 - 5.4e-31 106.2 0.9 6.4e-31 106.0 0.6 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF608 PF04685.8 EGO20897.1 - 0.044 12.4 0.0 0.045 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF608 DUF1777 PF08648.7 EGO20898.1 - 1.5e-24 86.7 40.6 1.5e-24 86.7 28.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) RRM_6 PF14259.1 EGO20899.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO20900.1 - 1.8e-11 43.4 0.0 5e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO20900.1 - 2.5e-08 33.7 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO20900.1 - 5.1e-05 23.0 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 EGO20901.1 - 2.4e-44 150.7 0.0 7.2e-44 149.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO20901.1 - 6.9e-09 35.5 0.1 2.2e-08 33.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO20901.1 - 8.1e-08 32.3 0.2 2.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGO20901.1 - 3.5e-07 30.3 0.1 2.3e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EGO20901.1 - 3.3e-06 26.1 0.0 6.5e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EGO20901.1 - 3.6e-06 27.1 2.6 0.00013 22.0 0.4 3.2 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EGO20901.1 - 0.00011 22.1 0.7 0.00036 20.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EGO20901.1 - 0.00015 21.4 0.2 0.00043 19.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGO20901.1 - 0.00019 21.3 0.0 0.00081 19.2 0.0 2.0 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 EGO20901.1 - 0.00076 18.5 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGO20901.1 - 0.0009 20.0 0.0 0.0043 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO20901.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase CENP-F_leu_zip PF10473.4 EGO20901.1 - 0.0015 18.4 0.4 0.0026 17.6 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NACHT PF05729.7 EGO20901.1 - 0.0018 17.9 0.2 0.059 13.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.8 EGO20901.1 - 0.002 16.8 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus UPF0079 PF02367.12 EGO20901.1 - 0.0022 17.5 0.1 0.022 14.3 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EGO20901.1 - 0.0026 17.1 0.8 0.0066 15.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EGO20901.1 - 0.0027 17.4 0.5 0.011 15.4 0.0 2.3 3 0 0 3 3 2 1 NTPase AAA_11 PF13086.1 EGO20901.1 - 0.0042 16.7 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGO20901.1 - 0.0047 16.3 3.7 0.013 14.9 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EGO20901.1 - 0.0048 16.7 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EGO20901.1 - 0.0074 15.4 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EGO20901.1 - 0.0094 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO20901.1 - 0.01 16.1 0.0 0.07 13.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGO20901.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EGO20901.1 - 0.012 15.1 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGO20901.1 - 0.016 14.9 1.3 0.29 10.7 0.0 2.9 2 1 0 3 3 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 EGO20901.1 - 0.027 13.2 0.0 0.073 11.8 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Zeta_toxin PF06414.7 EGO20901.1 - 0.038 13.0 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Bac_DnaA PF00308.13 EGO20901.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 EGO20901.1 - 0.059 12.8 0.2 0.99 8.8 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EGO20901.1 - 0.084 13.1 1.6 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGO20901.1 - 0.084 12.2 0.3 0.62 9.4 0.1 2.3 1 1 1 3 3 3 0 AAA-like domain KaiC PF06745.8 EGO20901.1 - 0.088 11.9 0.8 0.41 9.7 0.0 2.3 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EGO20901.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EGO20901.1 - 0.13 12.3 0.0 0.57 10.2 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain P5CR_dimer PF14748.1 EGO20902.1 - 5e-39 132.5 1.3 5e-39 132.5 0.9 2.1 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGO20902.1 - 1.1e-14 54.6 0.2 8.1e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGO20902.1 - 0.0054 16.1 0.0 0.0054 16.1 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA PDH PF02153.12 EGO20902.1 - 0.028 13.2 0.2 0.18 10.6 0.1 1.9 2 0 0 2 2 2 0 Prephenate dehydrogenase ANF_receptor PF01094.23 EGO20902.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Methyltransf_11 PF08241.7 EGO20903.1 - 2e-06 28.2 0.0 3.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO20903.1 - 0.0032 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain F420_ligase PF01996.11 EGO20903.1 - 0.0049 15.9 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Methyltransf_31 PF13847.1 EGO20903.1 - 0.0078 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20903.1 - 0.0081 16.7 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO20903.1 - 0.051 14.0 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGO20903.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain NAC PF01849.13 EGO20904.1 - 1.6e-20 72.3 0.0 2.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EGO20904.1 - 0.0016 18.1 0.7 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EGO20904.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF1264 PF06884.6 EGO20905.1 - 2.7e-68 228.7 0.6 5.2e-68 227.7 0.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1264) V-SNARE PF05008.10 EGO20906.1 - 0.038 14.1 0.7 0.038 14.1 0.5 4.3 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus Filament PF00038.16 EGO20906.1 - 2.4 7.5 34.6 0.047 13.1 4.9 3.6 1 1 1 3 3 3 0 Intermediate filament protein HSP90 PF00183.13 EGO20907.1 - 1.7e-256 851.7 29.6 2e-256 851.5 20.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EGO20907.1 - 2.1e-10 40.2 0.0 4.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGO20907.1 - 5.1e-10 39.1 0.1 5.1e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C37 PF05416.7 EGO20907.1 - 0.62 8.2 8.3 0.32 9.2 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase TRAP_alpha PF03896.11 EGO20907.1 - 4.4 6.2 13.2 0.24 10.3 5.3 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 EGO20907.1 - 7.7 5.8 21.2 0.51 9.6 10.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 EGO20907.1 - 8.9 6.1 10.0 8.2 6.2 3.6 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain Aminotran_5 PF00266.14 EGO20908.1 - 5.6e-35 120.7 0.0 6.9e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TRAPPC10 PF12584.3 EGO20910.1 - 1.7e-27 95.7 0.0 5.5e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.7 EGO20910.1 - 0.017 13.4 0.0 1.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 EGO20910.1 - 0.028 14.2 0.0 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 Gryzun, putative Golgi trafficking ALG3 PF05208.8 EGO20913.1 - 3.1e-124 414.9 12.7 3.8e-124 414.6 8.8 1.0 1 0 0 1 1 1 1 ALG3 protein Lyase_1 PF00206.15 EGO20914.1 - 2.2e-97 325.9 0.0 3e-97 325.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EGO20914.1 - 8.8e-29 99.3 0.1 1.8e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal bZIP_1 PF00170.16 EGO20916.1 - 0.016 15.1 2.0 0.016 15.1 1.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 EGO20916.1 - 0.018 15.3 1.3 0.054 13.8 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EGO20916.1 - 0.026 14.0 2.1 0.099 12.1 1.5 2.0 1 0 0 1 1 1 0 Septum formation initiator K-box PF01486.12 EGO20916.1 - 1.8 8.3 7.0 0.36 10.6 1.2 2.2 2 0 0 2 2 2 0 K-box region Transposase_21 PF02992.9 EGO20917.1 - 1.1e-07 31.2 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EGO20917.1 - 0.0083 15.5 0.2 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PIG-H PF10181.4 EGO20918.1 - 1.1e-12 47.4 0.0 1.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component RabGAP-TBC PF00566.13 EGO20919.1 - 1.8e-10 40.6 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phtf-FEM1B_bdg PF12129.3 EGO20920.1 - 3.5 6.9 5.7 7.2 5.9 3.9 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor MFS_1 PF07690.11 EGO20921.1 - 2e-09 36.6 5.6 2.5e-09 36.3 3.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EGO20921.1 - 4.6e-08 32.6 0.3 6e-08 32.2 0.2 1.1 1 0 0 1 1 1 1 Nodulin-like Cytochrom_B_N PF00033.14 EGO20921.1 - 0.0027 17.0 1.7 0.0045 16.3 0.1 2.0 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB MFS_1_like PF12832.2 EGO20921.1 - 0.12 12.2 5.6 0.25 11.1 2.5 2.3 2 0 0 2 2 2 0 MFS_1 like family Ni_hydr_CYTB PF01292.15 EGO20921.1 - 0.12 11.7 0.2 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 ABC2_membrane_4 PF12730.2 EGO20921.1 - 0.85 8.7 11.0 0.075 12.1 2.8 2.3 3 0 0 3 3 3 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EGO20921.1 - 2.3 7.3 12.3 0.4 9.8 5.7 1.7 2 1 0 2 2 2 0 ABC-2 type transporter EmrE PF13536.1 EGO20921.1 - 6 7.1 10.9 1.4 9.1 4.8 2.1 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DIOX_N PF14226.1 EGO20922.1 - 4.8e-26 91.5 0.0 7.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO20922.1 - 1e-16 61.0 0.0 1.9e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Far-17a_AIG1 PF04750.9 EGO20923.1 - 9.3e-21 73.9 1.5 1e-20 73.7 1.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SNARE PF05739.14 EGO20924.1 - 6.5e-13 48.1 0.8 6.5e-13 48.1 0.5 2.5 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGO20924.1 - 3.5e-12 46.3 12.5 3.8e-12 46.2 2.8 2.7 3 0 0 3 3 2 1 Syntaxin MCPsignal PF00015.16 EGO20924.1 - 0.0024 17.4 10.9 0.0042 16.6 0.6 2.3 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 EGO20924.1 - 0.0035 17.3 8.6 0.0035 17.3 5.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Tweety PF04906.8 EGO20924.1 - 0.019 13.3 4.4 0.074 11.4 0.2 2.3 2 0 0 2 2 2 0 Tweety VitD-bind_III PF09164.5 EGO20924.1 - 0.026 14.1 0.2 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Vitamin D binding protein, domain III BLOC1_2 PF10046.4 EGO20924.1 - 0.032 14.3 5.7 4.5 7.4 0.2 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.16 EGO20924.1 - 0.054 13.7 7.3 0.25 11.6 0.3 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF1659 PF07872.6 EGO20924.1 - 0.056 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) NPV_P10 PF05531.7 EGO20924.1 - 0.3 11.3 2.8 30 4.9 0.3 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.5 EGO20924.1 - 0.51 10.1 2.9 0.73 9.6 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 TMEM154 PF15102.1 EGO20924.1 - 0.83 9.3 6.3 0.096 12.3 0.9 2.0 2 0 0 2 2 2 0 TMEM154 protein family HeLo PF14479.1 EGO20924.1 - 2.7 7.6 12.3 0.8 9.4 2.2 2.6 1 1 1 3 3 3 0 Prion-inhibition and propagation LOH1CR12 PF10158.4 EGO20924.1 - 2.9 7.6 6.1 9.7 5.9 0.0 2.7 3 1 0 3 3 3 0 Tumour suppressor protein DUF4094 PF13334.1 EGO20924.1 - 2.9 8.3 9.5 3.4 8.1 0.0 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4094) Synaptobrevin PF00957.16 EGO20924.1 - 7.3 6.2 13.6 12 5.6 4.2 3.2 2 2 0 2 2 2 0 Synaptobrevin Wbp11 PF09429.5 EGO20924.1 - 8.5 6.4 10.7 1.6 8.7 0.1 3.6 3 1 1 4 4 4 0 WW domain binding protein 11 Cas1_AcylT PF07779.7 EGO20925.1 - 1.4e-152 508.6 21.2 1.6e-150 501.7 14.7 2.0 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EGO20925.1 - 1.1e-27 97.5 0.0 1.8e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p zf-AN1 PF01428.11 EGO20926.1 - 6.2e-09 35.5 9.4 9.5e-09 34.9 6.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 EGO20926.1 - 1.2 9.0 7.6 1.9 8.4 5.0 1.6 1 1 0 1 1 1 0 IBR domain Aminotran_1_2 PF00155.16 EGO20927.1 - 9.5e-85 284.6 0.0 1.1e-84 284.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.17 EGO20928.1 - 7.8e-15 53.5 10.8 0.0023 17.8 0.1 8.9 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 EGO20928.1 - 3.6e-11 43.1 7.5 0.00023 21.3 0.1 6.6 5 2 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EGO20928.1 - 0.00012 22.4 11.1 0.25 11.8 0.1 6.1 6 0 0 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 EGO20928.1 - 0.018 14.4 0.0 0.16 11.2 0.0 2.4 3 0 0 3 3 3 0 CLASP N terminal DUF1218 PF06749.7 EGO20929.1 - 3.9 8.0 10.4 0.096 13.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) FA_desaturase PF00487.19 EGO20929.1 - 9.2 5.6 8.5 25 4.1 5.9 1.8 1 1 0 1 1 1 0 Fatty acid desaturase Tom37 PF10568.4 EGO20930.1 - 9.4e-15 54.6 0.5 1.6e-14 53.8 0.4 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 EGO20930.1 - 1.5e-12 47.7 0.8 4e-12 46.3 0.0 2.2 2 1 0 2 2 2 1 Tom37 C-terminal domain GST_C_2 PF13410.1 EGO20930.1 - 7.9e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO20930.1 - 0.0027 17.6 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetone_carb_G PF08882.6 EGO20931.1 - 0.082 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Ion_trans PF00520.26 EGO20932.1 - 1.5e-05 24.3 1.2 2.4e-05 23.7 0.8 1.3 1 0 0 1 1 1 1 Ion transport protein Transcrip_act PF04949.8 EGO20932.1 - 0.17 11.4 1.4 4.6 6.8 0.2 2.1 2 0 0 2 2 2 0 Transcriptional activator PalH PF08733.5 EGO20933.1 - 0.066 12.0 4.8 0.087 11.6 3.3 1.3 1 0 0 1 1 1 0 PalH/RIM21 FA_desaturase PF00487.19 EGO20933.1 - 1.3 8.3 8.1 2.3 7.5 5.6 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Nol1_Nop2_Fmu PF01189.12 EGO20936.1 - 1.7e-100 336.0 0.0 2.4e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EGO20936.1 - 0.00071 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 EGO20936.1 - 0.0055 16.2 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGO20936.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGO20936.1 - 0.032 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EGO20936.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2404 PF10296.4 EGO20938.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) DUF668 PF05003.7 EGO20938.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Aminotran_5 PF00266.14 EGO20939.1 - 1.2e-15 57.1 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.14 EGO20940.1 - 1.4e-14 53.9 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EGO20940.1 - 0.012 14.4 0.0 0.14 10.9 0.0 2.2 2 1 0 2 2 2 0 Squalene epoxidase AT_hook PF02178.14 EGO20941.1 - 3.6e-06 26.0 52.6 0.03 13.9 4.5 4.5 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.8 EGO20942.1 - 5.7e-14 52.6 0.5 1.2e-13 51.6 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EGO20942.1 - 0.00037 19.9 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pkinase PF00069.20 EGO20946.1 - 3.2e-55 187.1 0.0 4.2e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO20946.1 - 4.9e-27 94.6 0.0 6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO20946.1 - 0.00059 18.8 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO20946.1 - 0.0033 17.2 0.1 0.01 15.5 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family DEAD PF00270.24 EGO20948.1 - 2.8e-41 140.8 0.0 2.9e-40 137.5 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO20948.1 - 1.1e-24 86.0 0.1 2.5e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO20948.1 - 0.0025 17.6 1.2 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3421 PF11901.3 EGO20948.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) DUF605 PF04652.11 EGO20948.1 - 4.7 6.5 15.8 7.8 5.7 11.0 1.3 1 0 0 1 1 1 0 Vta1 like EF-hand_8 PF13833.1 EGO20949.1 - 0.001 18.6 0.2 0.0064 16.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF_assoc_2 PF08356.7 EGO20949.1 - 0.014 15.1 0.1 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 EF hand associated EF_assoc_1 PF08355.7 EGO20949.1 - 0.029 13.6 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Methyltransf_16 PF10294.4 EGO20950.1 - 1.8e-18 66.6 0.0 6.5e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EGO20950.1 - 1.6e-06 27.9 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO20950.1 - 6.1e-06 26.7 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO20950.1 - 0.0024 17.9 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO20950.1 - 0.0052 15.9 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0146 PF03686.8 EGO20950.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) TehB PF03848.9 EGO20950.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.11 EGO20950.1 - 0.092 12.3 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein DUF4072 PF13284.1 EGO20950.1 - 0.093 12.9 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) MTS PF05175.9 EGO20950.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EGO20950.1 - 0.14 12.6 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Asn_synthase PF00733.16 EGO20951.1 - 5e-71 239.1 0.1 7.8e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGO20951.1 - 8.4e-35 119.2 0.0 1.4e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGO20951.1 - 3.4e-29 101.4 0.0 1.3e-28 99.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGO20951.1 - 1.4e-05 24.3 0.0 3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EGO20951.1 - 0.0014 17.4 0.0 2.9 6.4 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II QueC PF06508.8 EGO20951.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 EGO20951.1 - 0.026 13.4 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Aldo_ket_red PF00248.16 EGO20952.1 - 3.8e-49 167.0 0.0 4.2e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Syntaxin PF00804.20 EGO20953.1 - 4.6e-14 52.4 12.6 1.3e-13 50.9 2.2 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EGO20953.1 - 9.8e-14 50.7 3.3 9.8e-14 50.7 2.3 2.9 2 1 1 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 EGO20953.1 - 2.1e-06 27.6 13.2 6.9e-06 26.0 5.5 2.4 2 0 0 2 2 2 1 Syntaxin-like protein HHH_2 PF12826.2 EGO20953.1 - 0.00069 19.4 0.4 0.0017 18.1 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Laminin_II PF06009.7 EGO20953.1 - 0.0045 16.7 5.7 0.085 12.6 0.1 2.6 3 0 0 3 3 2 1 Laminin Domain II Spectrin PF00435.16 EGO20953.1 - 0.0058 16.9 8.9 0.46 10.7 0.5 3.2 3 0 0 3 3 3 2 Spectrin repeat Med4 PF10018.4 EGO20953.1 - 0.0062 15.9 9.7 0.031 13.6 1.0 2.8 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 FUSC PF04632.7 EGO20953.1 - 0.0067 14.9 1.2 0.0067 14.9 0.8 2.3 1 1 0 2 2 2 1 Fusaric acid resistance protein family BLOC1_2 PF10046.4 EGO20953.1 - 0.0081 16.2 7.2 0.27 11.3 0.1 3.6 3 1 1 4 4 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ACC_epsilon PF13822.1 EGO20953.1 - 0.012 15.8 1.9 0.048 14.0 0.0 2.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DASH_Dam1 PF08653.5 EGO20953.1 - 0.013 15.2 1.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Synaptobrevin PF00957.16 EGO20953.1 - 0.018 14.6 2.8 0.093 12.3 0.0 2.7 2 1 0 2 2 2 0 Synaptobrevin MCPsignal PF00015.16 EGO20953.1 - 0.037 13.5 11.7 0.28 10.7 0.9 2.6 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.5 EGO20953.1 - 0.066 12.8 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Serine_rich PF08824.5 EGO20953.1 - 0.067 12.9 2.1 0.32 10.7 0.2 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain Fib_alpha PF08702.5 EGO20953.1 - 0.49 10.5 9.8 5.5 7.1 1.2 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EGO20953.1 - 0.74 10.1 5.2 14 5.9 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LOH1CR12 PF10158.4 EGO20953.1 - 0.77 9.5 5.7 1.7 8.4 0.1 2.8 2 1 0 2 2 2 0 Tumour suppressor protein Allexi_40kDa PF05549.6 EGO20953.1 - 0.8 8.9 7.0 0.88 8.8 1.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TBPIP PF07106.8 EGO20953.1 - 0.85 9.1 11.3 1.3 8.5 0.4 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2077 PF09850.4 EGO20953.1 - 0.91 8.8 5.3 0.55 9.6 0.1 2.8 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) WXG100 PF06013.7 EGO20953.1 - 0.95 9.5 9.0 6.5 6.8 0.3 4.0 2 2 1 3 3 3 0 Proteins of 100 residues with WXG COG5 PF10392.4 EGO20953.1 - 1 9.2 7.3 0.19 11.7 1.3 2.3 3 0 0 3 3 2 0 Golgi transport complex subunit 5 SPT16 PF08644.6 EGO20953.1 - 1.2 8.9 7.5 0.31 10.8 0.2 2.6 1 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) IncA PF04156.9 EGO20953.1 - 2.3 7.7 22.8 27 4.2 0.0 3.8 2 1 0 2 2 1 0 IncA protein TarH PF02203.10 EGO20953.1 - 3 7.6 13.9 1 9.1 4.3 2.9 1 1 2 3 3 3 0 Tar ligand binding domain homologue Baculo_PEP_C PF04513.7 EGO20953.1 - 3.4 7.5 10.3 12 5.7 0.2 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCP_MauG PF03150.9 EGO20953.1 - 3.6 7.8 6.4 1.1 9.5 2.0 1.9 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase Lipase_chap PF03280.9 EGO20953.1 - 9.3 5.7 21.3 0.021 14.3 4.6 2.7 3 0 0 3 3 3 0 Proteobacterial lipase chaperone protein CDP-OH_P_transf PF01066.16 EGO20954.1 - 2e-19 69.7 3.6 2e-19 69.7 2.5 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AAA PF00004.24 EGO20955.1 - 2.6e-36 124.7 0.0 6.3e-36 123.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO20955.1 - 9.7e-06 25.6 2.5 0.0018 18.2 0.0 3.5 2 1 2 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 EGO20955.1 - 6.6e-05 23.7 0.0 0.0003 21.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO20955.1 - 0.00026 20.7 0.0 0.0045 16.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO20955.1 - 0.00043 20.4 0.0 0.012 15.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO20955.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO20955.1 - 0.0018 17.8 0.0 0.0087 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGO20955.1 - 0.0095 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO20955.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGO20955.1 - 0.016 15.4 0.9 0.11 12.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.12 EGO20955.1 - 0.022 14.2 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGO20955.1 - 0.022 14.4 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 1 0 Part of AAA domain AAA_14 PF13173.1 EGO20955.1 - 0.035 14.0 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rep_4 PF05797.6 EGO20955.1 - 0.044 12.4 0.1 0.12 11.0 0.2 1.5 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) TIP49 PF06068.8 EGO20955.1 - 0.049 12.3 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EGO20955.1 - 0.059 12.7 0.4 2 7.7 0.1 2.5 1 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGO20955.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EGO20955.1 - 0.086 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EGO20955.1 - 0.11 11.9 0.1 19 4.5 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain Rad17 PF03215.10 EGO20955.1 - 0.14 10.8 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EGO20955.1 - 0.14 11.2 0.3 0.34 10.0 0.2 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGO20955.1 - 0.16 11.0 1.6 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SMC_Nse1 PF07574.8 EGO20956.1 - 3.4e-22 79.0 0.0 6.5e-21 74.8 0.0 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex CDP-OH_P_transf PF01066.16 EGO20957.1 - 4.4e-12 46.2 4.5 9.1e-12 45.1 3.1 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DNA_primase_lrg PF04104.9 EGO20958.1 - 3.8e-79 265.6 0.0 6e-79 264.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit USP7_ICP0_bdg PF12436.3 EGO20961.1 - 6.6e-84 281.0 0.1 1.9e-83 279.5 0.0 1.8 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGO20961.1 - 3e-71 239.2 2.6 1.2e-66 224.1 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EGO20961.1 - 7e-58 195.8 0.1 1e-57 195.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO20961.1 - 1.6e-33 116.4 0.0 2.3e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGO20961.1 - 4.5e-07 30.1 0.0 4.7e-06 26.8 0.0 2.7 3 1 0 3 3 3 1 MATH domain UN_NPL4 PF11543.3 EGO20961.1 - 0.07 13.4 0.1 0.65 10.3 0.1 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 EGO20962.1 - 1.5e-51 174.4 0.0 1.9e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Citrate_synt PF00285.16 EGO20963.1 - 4.5e-102 341.4 0.0 5.1e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase B56 PF01603.15 EGO20964.1 - 7e-171 568.3 6.5 8.3e-171 568.0 4.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Fe_bilin_red PF05996.7 EGO20964.1 - 0.025 14.0 1.0 0.052 13.0 0.7 1.4 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Sec7_N PF12783.2 EGO20964.1 - 0.05 13.0 1.4 2.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ATP-cone PF03477.11 EGO20964.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP cone domain HSP70 PF00012.15 EGO20965.1 - 1.2e-273 908.6 3.6 1.3e-273 908.4 2.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO20965.1 - 2.2e-15 56.1 0.0 3.2e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGO20965.1 - 0.0021 17.7 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EGO20965.1 - 0.0032 16.5 0.1 0.019 14.0 0.0 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.6 EGO20965.1 - 0.056 12.3 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 StbA protein DDR PF08841.5 EGO20965.1 - 0.073 11.8 0.3 0.53 9.0 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RabGAP-TBC PF00566.13 EGO20969.1 - 2.2e-12 46.9 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAD_binding_2 PF00890.19 EGO20970.1 - 1.5e-126 422.6 2.3 1.8e-126 422.3 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGO20970.1 - 2.8e-45 153.2 0.2 4.3e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 EGO20970.1 - 4.2e-06 26.0 0.0 0.0081 15.2 0.0 3.1 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 EGO20970.1 - 4.3e-06 26.7 0.0 0.0022 17.9 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO20970.1 - 5.3e-06 25.5 2.3 0.0081 15.0 1.5 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 EGO20970.1 - 0.0002 20.4 0.6 0.0025 16.7 0.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGO20970.1 - 0.0036 16.4 0.1 0.0065 15.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGO20970.1 - 0.12 12.3 0.2 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO20970.1 - 0.13 10.7 2.4 0.34 9.3 0.6 2.4 4 0 0 4 4 4 0 HI0933-like protein Sgf11 PF08209.6 EGO20972.1 - 6.8e-14 50.8 0.2 1.4e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EGO20972.1 - 0.14 11.8 0.3 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC_membrane_2 PF06472.10 EGO20973.1 - 1.7e-90 303.0 2.1 2.3e-90 302.5 1.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGO20973.1 - 4.8e-17 62.5 0.0 1.1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGO20973.1 - 2.1e-05 23.9 0.2 0.0074 15.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGO20973.1 - 7.1e-05 22.9 0.1 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGO20973.1 - 0.016 14.4 0.0 0.05 12.8 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO20973.1 - 0.018 15.3 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGO20973.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGO20973.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4294 PF14127.1 EGO20973.1 - 0.098 12.2 0.1 0.25 10.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DUF4258 PF14076.1 EGO20973.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) SHR3_chaperone PF08229.6 EGO20974.1 - 1.8e-18 66.2 2.2 2e-18 66.0 1.5 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 EGO20974.1 - 0.053 13.9 1.0 0.061 13.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) LETM1 PF07766.8 EGO20975.1 - 3e-99 331.4 0.1 3e-99 331.4 0.1 2.1 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 EGO20975.1 - 0.00022 20.6 1.8 0.02 14.4 0.0 3.6 4 0 0 4 4 4 1 SAP domain EF-hand_6 PF13405.1 EGO20975.1 - 0.0059 16.3 0.0 5 7.2 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EGO20975.1 - 0.0082 15.3 0.1 0.69 9.3 0.0 3.2 3 0 0 3 3 3 1 EF hand Peptidase_S46 PF10459.4 EGO20975.1 - 5.9 5.1 10.7 8.7 4.6 7.4 1.1 1 0 0 1 1 1 0 Peptidase S46 2OG-FeII_Oxy_2 PF13532.1 EGO20976.1 - 1.2e-36 126.4 0.0 1.9e-34 119.2 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily GPI PF06560.6 EGO20977.1 - 0.0078 15.2 0.1 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) TF_Zn_Ribbon PF08271.7 EGO20977.1 - 1.4 8.3 5.1 3 7.2 3.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Glycos_transf_1 PF00534.15 EGO20978.1 - 4e-20 71.9 0.0 7.8e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO20978.1 - 7.3e-10 39.1 0.0 2.6e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGO20978.1 - 2.4e-05 24.5 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EGO20978.1 - 0.016 13.6 0.0 0.22 9.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 20 DNA_pol_phi PF04931.8 EGO20980.1 - 1e-61 208.7 10.6 1.2e-60 205.2 7.3 2.4 1 1 0 1 1 1 1 DNA polymerase phi MutS_V PF00488.16 EGO20981.1 - 4.2e-82 275.0 0.0 7.4e-82 274.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO20981.1 - 3.4e-37 128.2 0.3 9.5e-37 126.7 0.2 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGO20981.1 - 1e-17 64.1 0.2 2.8e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EGO20981.1 - 2e-07 31.0 0.2 5.6e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EGO20981.1 - 0.0004 20.4 0.1 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain II Cut8_N PF14482.1 EGO20981.1 - 0.33 10.9 3.8 19 5.3 0.0 2.8 2 0 0 2 2 2 0 Cut8 proteasome-binding domain ATP12 PF07542.6 EGO20982.1 - 1.3e-39 134.8 0.8 2.1e-39 134.2 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein DUF3025 PF11227.3 EGO20982.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) DUF2218 PF09981.4 EGO20982.1 - 0.063 13.4 0.8 4.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) Nt_Gln_amidase PF09764.4 EGO20983.1 - 1.7e-44 151.3 0.0 1.9e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase BTB PF00651.26 EGO20984.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.21 EGO20986.1 - 9.9e-41 138.4 0.0 1.1e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO20986.1 - 8.1e-05 22.3 0.0 8.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGO20986.1 - 0.03 13.9 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain SPRY PF00622.23 EGO20987.1 - 3e-10 40.2 0.0 2.5e-09 37.2 0.0 2.3 3 0 0 3 3 3 1 SPRY domain PhoD PF09423.5 EGO20988.1 - 0.0053 15.3 0.0 0.055 12.0 0.0 2.2 3 0 0 3 3 3 1 PhoD-like phosphatase CAP_N PF01213.14 EGO20989.1 - 4.8e-84 282.2 24.5 4.1e-82 275.9 17.0 3.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EGO20989.1 - 5.2e-57 191.6 6.7 6.8e-57 191.2 4.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGO20989.1 - 0.18 11.2 4.7 0.14 11.5 1.6 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor C 4HBT_3 PF13622.1 EGO20989.1 - 4.4 6.9 10.4 1.8 8.2 0.6 2.4 2 0 0 2 2 2 0 Thioesterase-like superfamily RF-1 PF00472.15 EGO20990.1 - 1.2e-24 86.3 6.7 1.2e-24 86.3 4.6 1.6 2 0 0 2 2 2 1 RF-1 domain Peptidase_M16_C PF05193.16 EGO20990.1 - 0.13 11.9 0.2 0.98 9.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase M16 inactive domain E3_binding PF02817.12 EGO20990.1 - 0.91 9.2 0.0 0.91 9.2 0.0 2.5 3 0 0 3 3 3 0 e3 binding domain Linker_histone PF00538.14 EGO20991.1 - 1.4e-16 60.3 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family TFIIA PF03153.8 EGO20991.1 - 1.8 8.3 6.2 1.9 8.3 4.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.17 EGO20992.1 - 9.8e-71 238.6 0.0 7.9e-70 235.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 EI24 PF07264.6 EGO20993.1 - 2.4e-33 115.3 14.7 3.5e-33 114.8 10.2 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 EGO20993.1 - 0.013 15.4 1.7 0.39 10.6 1.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) Lipase_GDSL_2 PF13472.1 EGO20995.1 - 2.5e-26 92.8 0.0 3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO20995.1 - 6.7e-22 78.4 0.0 8.1e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.15 EGO20996.1 - 1.9e-14 53.9 0.0 3.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.19 EGO20997.1 - 1.7e-138 462.2 9.8 1.9e-138 462.1 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EGO20997.1 - 0.036 13.2 0.0 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 Telomere recombination TPR_11 PF13414.1 EGO20998.1 - 8e-33 111.9 7.4 1.4e-09 37.4 0.0 7.9 5 1 3 8 8 8 5 TPR repeat TPR_2 PF07719.12 EGO20998.1 - 4.9e-30 101.0 2.9 0.00018 21.1 0.1 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGO20998.1 - 1.4e-27 94.1 3.6 5.1e-08 32.1 0.2 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGO20998.1 - 1.9e-25 88.9 9.8 3.2e-07 30.8 0.0 8.0 7 1 1 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EGO20998.1 - 3.4e-20 71.9 11.9 9.6e-14 51.2 0.9 5.4 3 1 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGO20998.1 - 1.1e-19 70.4 5.8 3.3e-06 27.3 0.0 6.2 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO20998.1 - 3.5e-17 61.1 6.1 0.018 15.2 0.0 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO20998.1 - 3.8e-16 58.7 13.1 2.3e-05 24.2 0.0 7.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGO20998.1 - 9.8e-16 56.8 12.7 0.3 11.8 0.0 10.2 4 1 6 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO20998.1 - 1.2e-15 55.9 0.1 0.0016 18.1 0.1 7.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGO20998.1 - 3.2e-10 39.7 4.2 0.28 11.7 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO20998.1 - 9.2e-09 35.0 8.1 0.0021 17.8 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO20998.1 - 6.6e-08 31.7 2.4 0.33 10.8 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGO20998.1 - 0.0067 15.5 16.7 0.016 14.2 0.1 3.9 3 1 2 5 5 5 3 Tetratricopeptide repeat PPTA PF01239.17 EGO20998.1 - 0.014 14.7 0.1 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_20 PF14561.1 EGO20998.1 - 0.065 13.3 0.4 13 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SRR1 PF07985.7 EGO21000.1 - 4.9e-17 61.6 0.2 1.6e-16 59.9 0.2 1.8 2 0 0 2 2 2 1 SRR1 PUA PF01472.15 EGO21001.1 - 8.2e-15 54.2 0.0 1.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 PUA domain CRM1_C PF08767.6 EGO21002.1 - 2.6e-132 440.5 0.1 2.6e-132 440.5 0.1 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EGO21002.1 - 2.6e-42 144.2 6.8 2.4e-41 141.1 4.7 2.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EGO21002.1 - 1.6e-12 47.1 0.1 7.2e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1654 PF07867.6 EGO21002.1 - 0.07 12.5 0.0 0.75 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) ADH_zinc_N_2 PF13602.1 EGO21003.1 - 3.3e-18 66.8 0.0 7.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGO21003.1 - 2.7e-11 43.1 0.0 4.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO21003.1 - 0.014 15.1 0.1 0.073 12.8 0.0 2.1 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain E1-E2_ATPase PF00122.15 EGO21004.1 - 1.2e-66 224.0 10.3 3.8e-66 222.4 3.5 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO21004.1 - 1.5e-44 151.6 7.8 1.5e-44 151.6 5.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO21004.1 - 4.5e-33 115.4 0.0 3.7e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO21004.1 - 1.4e-21 76.2 0.0 2.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGO21004.1 - 7.1e-21 73.4 2.1 9.8e-21 73.0 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGO21004.1 - 1.9e-15 57.5 0.0 4.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO21004.1 - 6.4e-07 29.1 1.6 4.3e-06 26.4 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO21004.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4518 PF15008.1 EGO21004.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF572 PF04502.8 EGO21005.1 - 1 8.5 7.6 1.9 7.6 5.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) CBP4 PF07960.6 EGO21006.1 - 5.7e-09 35.6 0.0 7.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 CBP4 NDUF_B4 PF07225.7 EGO21006.1 - 0.069 12.9 0.1 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF4574 PF15141.1 EGO21006.1 - 0.12 12.1 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4574) DUF3464 PF11947.3 EGO21006.1 - 0.81 9.1 2.8 0.62 9.5 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) Arrestin_C PF02752.17 EGO21007.1 - 0.0001 22.3 0.0 0.00033 20.7 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Nuc_sug_transp PF04142.10 EGO21008.1 - 4.2e-08 32.5 1.4 6e-08 32.0 1.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EGO21008.1 - 9.8e-08 31.2 6.5 9.8e-08 31.2 4.5 1.5 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EGO21008.1 - 8.8e-07 29.0 22.7 3.7e-05 23.7 2.0 3.0 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EGO21008.1 - 8.3e-05 22.2 16.8 0.029 14.0 0.5 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EGO21008.1 - 0.0002 21.4 3.8 0.0002 21.4 2.7 3.3 4 1 0 4 4 4 1 Multidrug resistance efflux transporter MitoNEET_N PF10660.4 EGO21008.1 - 0.092 12.6 2.2 0.1 12.4 0.1 2.2 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus SHQ1 PF04925.10 EGO21010.1 - 1.4e-51 174.6 0.0 2.4e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.11 EGO21010.1 - 0.00029 21.3 0.0 0.00047 20.6 0.0 1.4 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 EGO21010.1 - 0.00057 19.4 0.0 0.00092 18.7 0.0 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Chorismate_bind PF00425.13 EGO21011.1 - 1.1e-87 293.6 0.0 1.6e-87 293.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGO21011.1 - 3.8e-31 107.9 0.0 9.2e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.15 EGO21012.1 - 1.1e-46 158.7 0.0 2.5e-44 151.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 HSP70 PF00012.15 EGO21013.1 - 8.8e-243 806.6 5.1 1.1e-242 806.3 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO21013.1 - 6.4e-16 57.8 0.4 6.6e-15 54.5 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EGO21013.1 - 0.0058 15.4 0.2 0.05 12.4 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 EGO21013.1 - 0.014 14.6 0.1 1.9 7.7 0.0 2.6 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EGO21013.1 - 0.034 13.0 0.0 0.07 12.0 0.0 1.6 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.11 EGO21013.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EGO21013.1 - 0.43 9.6 3.7 0.22 10.5 0.1 2.3 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase AAA PF00004.24 EGO21014.1 - 6.4e-14 52.2 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGO21014.1 - 6.3e-12 45.4 0.0 4.6e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGO21014.1 - 4.5e-09 35.5 0.0 1.7e-06 27.0 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EGO21014.1 - 8.9e-08 32.0 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EGO21014.1 - 4.8e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO21014.1 - 7.8e-05 22.3 0.0 8.9e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO21014.1 - 7.9e-05 22.3 0.0 0.00033 20.3 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGO21014.1 - 0.00011 22.2 0.0 0.00054 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGO21014.1 - 0.00018 20.6 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EGO21014.1 - 0.00029 20.4 0.0 0.00095 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGO21014.1 - 0.00029 20.7 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO21014.1 - 0.00071 19.3 0.0 0.0032 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO21014.1 - 0.0036 16.5 0.0 0.034 13.2 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EGO21014.1 - 0.0044 16.0 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGO21014.1 - 0.0051 16.4 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO21014.1 - 0.0087 15.5 0.2 0.44 9.9 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EGO21014.1 - 0.024 14.0 0.0 0.061 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO21014.1 - 0.028 15.2 0.0 0.089 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGO21014.1 - 0.051 13.8 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO21014.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGO21014.1 - 0.069 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 EGO21014.1 - 0.069 12.6 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase HTH_7 PF02796.10 EGO21014.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase FtsK_SpoIIIE PF01580.13 EGO21014.1 - 0.087 12.2 0.2 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EGO21014.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain CAF1A PF12253.3 EGO21015.1 - 2e-18 66.2 11.5 2e-18 66.2 8.0 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Spc24 PF08286.6 EGO21016.1 - 1.1e-13 50.8 0.0 2.9e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 EGO21016.1 - 0.057 11.2 0.2 0.066 11.0 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAT PF03127.9 EGO21016.1 - 0.08 12.9 0.4 0.77 9.7 0.0 2.4 2 1 0 2 2 2 0 GAT domain IncA PF04156.9 EGO21016.1 - 0.12 11.9 1.6 0.2 11.2 1.1 1.3 1 0 0 1 1 1 0 IncA protein Sec2p PF06428.6 EGO21016.1 - 0.13 12.1 3.4 0.44 10.4 0.7 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p GAS PF13851.1 EGO21016.1 - 0.22 10.6 3.1 0.32 10.1 2.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EGO21016.1 - 0.4 10.4 5.8 0.52 10.0 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EGO21016.1 - 0.56 9.2 3.4 0.72 8.8 2.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 gag-asp_proteas PF13975.1 EGO21019.1 - 3.7e-11 42.6 0.0 5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO21019.1 - 1e-07 31.9 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO21019.1 - 1.5e-06 28.6 0.1 2.3e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO21019.1 - 0.045 13.3 0.0 0.049 13.1 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.12 EGO21020.1 - 6.6e-10 38.9 7.7 3.6e-06 26.9 0.7 3.4 3 0 0 3 3 3 2 Retrotransposon gag protein zf-CCHC PF00098.18 EGO21020.1 - 0.0019 18.0 4.2 0.003 17.4 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle RCC1 PF00415.13 EGO21023.1 - 3.3e-22 78.4 3.4 2.4e-05 24.4 0.1 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO21023.1 - 1.5e-09 37.1 32.1 4.1e-07 29.4 0.5 7.5 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 EGO21024.1 - 1.7e-05 24.4 7.2 0.0026 17.5 0.1 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EGO21024.1 - 0.00017 21.6 0.6 0.0087 16.3 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.1 EGO21024.1 - 0.0084 15.8 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Reg_prop PF07494.6 EGO21024.1 - 0.031 14.2 0.5 13 6.1 0.1 3.8 3 1 0 3 3 3 0 Two component regulator propeller Gln-synt_C PF00120.19 EGO21025.1 - 4.5e-57 193.1 0.0 3.3e-56 190.2 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3074 PF11274.3 EGO21026.1 - 6.5e-36 123.6 0.0 8.3e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ribosomal_L27 PF01016.14 EGO21027.1 - 9.6e-32 108.6 0.9 1.3e-31 108.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Skp1 PF01466.14 EGO21028.1 - 9.6e-40 134.4 1.7 1.5e-39 133.8 1.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGO21028.1 - 1.1e-23 83.0 0.4 2.9e-23 81.7 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EGO21028.1 - 3.3e-05 23.8 0.0 0.0029 17.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.9 EGO21028.1 - 0.06 13.0 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) mRNA_cap_enzyme PF01331.14 EGO21029.1 - 1.2e-47 162.0 0.0 1.7e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EGO21029.1 - 1.2e-17 64.1 0.0 2.3e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGO21029.1 - 4.8e-10 39.1 0.0 1.8e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Amidohydro_1 PF01979.15 EGO21031.1 - 2.7e-37 129.2 2.0 3.6e-37 128.7 1.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGO21031.1 - 4.7e-06 26.0 0.1 0.0039 16.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO21031.1 - 4.1e-05 23.3 0.0 4.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Zip PF02535.17 EGO21031.1 - 0.0049 15.9 2.2 0.006 15.6 1.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Amidohydro_4 PF13147.1 EGO21031.1 - 0.013 15.5 0.1 0.05 13.6 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase SelP_N PF04592.9 EGO21031.1 - 0.018 14.4 8.4 0.029 13.7 5.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lipase_3 PF01764.20 EGO21032.1 - 1e-06 28.4 0.0 2.3e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGO21032.1 - 0.0028 17.4 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO21032.1 - 0.013 15.3 0.1 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EGO21032.1 - 0.024 14.3 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EGO21032.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein CTP_transf_2 PF01467.21 EGO21033.1 - 7.6e-11 42.3 0.0 1.7e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EGO21033.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase zf-DHHC PF01529.15 EGO21035.1 - 2.2e-38 131.3 0.1 3.6e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Fungal_trans PF04082.13 EGO21037.1 - 1.3e-27 96.3 1.1 7.1e-27 93.8 0.5 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain LIM PF00412.17 EGO21038.1 - 2.2e-21 75.6 20.4 1.2e-11 44.4 4.5 3.2 3 0 0 3 3 3 3 LIM domain Vps39_2 PF10367.4 EGO21038.1 - 0.061 13.5 3.8 0.62 10.2 0.0 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EGO21038.1 - 3.9 7.5 12.6 0.29 11.1 2.6 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.9 EGO21038.1 - 4 7.1 8.6 5.9 6.6 0.1 3.9 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Syja_N PF02383.13 EGO21039.1 - 3.3e-87 292.2 0.0 4.9e-87 291.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EGO21039.1 - 8.8e-26 89.5 0.1 3e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase DUF2100 PF09873.4 EGO21039.1 - 0.21 11.0 0.0 0.84 9.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2100) Proteasome PF00227.21 EGO21040.1 - 6.2e-51 172.3 0.1 7.5e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Cys_Met_Meta_PP PF01053.15 EGO21041.1 - 9.4e-59 198.6 0.0 2.7e-58 197.0 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cys_Met_Meta_PP PF01053.15 EGO21042.1 - 9.2e-45 152.5 0.0 2e-44 151.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FMO-like PF00743.14 EGO21044.1 - 1.4e-36 125.8 0.0 2.8e-23 81.9 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO21044.1 - 1.2e-14 54.9 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO21044.1 - 6.5e-08 32.6 0.4 0.00016 21.6 0.0 3.8 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO21044.1 - 2.9e-07 30.3 3.5 7.3e-05 22.5 0.1 4.0 2 2 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO21044.1 - 0.00014 21.8 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO21044.1 - 0.0017 17.5 0.3 0.019 14.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO21044.1 - 0.024 13.0 2.8 0.25 9.7 0.1 3.1 3 1 1 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.14 EGO21044.1 - 0.22 10.5 2.4 0.69 8.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EGO21044.1 - 1.8 7.3 3.4 1.8 7.3 0.4 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CBM_1 PF00734.13 EGO21045.1 - 1.9e-09 37.0 12.1 1.9e-09 37.0 8.4 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain DOMON PF03351.12 EGO21045.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 DOMON domain Ribosomal_L7Ae PF01248.21 EGO21047.1 - 2.1e-05 23.9 0.1 2.3e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Phage-MuB_C PF09077.6 EGO21047.1 - 0.066 12.8 0.1 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Mu B transposition protein, C terminal UQ_con PF00179.21 EGO21048.1 - 3.7e-48 162.5 0.0 4.2e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO21048.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO21048.1 - 0.022 14.6 0.6 0.036 13.9 0.4 1.7 1 1 0 1 1 1 0 RWD domain DNA_binding_1 PF01035.15 EGO21049.1 - 9.6e-18 63.7 0.1 1.2e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain gag-asp_proteas PF13975.1 EGO21050.1 - 0.05 13.4 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Cas_Csa5 PF09702.5 EGO21050.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) DUF2371 PF10177.4 EGO21051.1 - 0.018 14.9 0.2 0.019 14.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF2892 PF11127.3 EGO21051.1 - 1.4 8.8 4.1 1.9 8.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF1713 PF08213.6 EGO21053.1 - 9.5e-07 28.3 16.4 1.4e-06 27.7 11.4 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Glyco_transf_22 PF03901.12 EGO21054.1 - 8.1e-66 222.7 22.3 1.6e-63 215.2 15.5 2.9 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3835 PF12927.2 EGO21056.1 - 1.7e-11 44.8 24.3 4.9e-11 43.4 0.1 5.1 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) SLY PF12485.3 EGO21056.1 - 0.082 13.1 8.1 0.035 14.3 2.7 2.5 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein KH_1 PF00013.24 EGO21057.1 - 2.9e-05 23.5 2.5 3.9e-05 23.2 0.7 1.9 2 0 0 2 2 2 1 KH domain GATase_2 PF00310.16 EGO21058.1 - 7.9e-17 60.9 0.2 2.6e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 EGO21058.1 - 5.4e-13 48.7 0.4 1e-12 47.8 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 EGO21058.1 - 3.2e-09 36.5 0.0 5.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGO21058.1 - 4.3e-07 29.9 0.0 8.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGO21058.1 - 0.022 13.4 0.0 0.099 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferases class-II S-AdoMet_synt_C PF02773.11 EGO21059.1 - 9.4e-75 248.9 0.2 1.6e-74 248.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EGO21059.1 - 5.3e-48 161.9 0.0 9.4e-48 161.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGO21059.1 - 1.6e-43 146.9 0.1 3.3e-43 145.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 EGO21059.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase Myotub-related PF06602.9 EGO21060.1 - 1.1e-126 422.4 0.0 1.4e-126 421.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGO21060.1 - 0.017 15.3 0.3 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO21060.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CBF PF03914.12 EGO21061.1 - 7.7e-40 136.0 3.5 3.5e-39 133.8 1.1 2.6 3 0 0 3 3 3 1 CBF/Mak21 family PaaX_C PF08223.6 EGO21061.1 - 0.0059 16.3 0.1 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain Cu_bind_like PF02298.12 EGO21062.1 - 0.0036 17.0 0.4 0.017 14.8 0.3 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain G-gamma PF00631.17 EGO21063.1 - 8.4e-24 83.1 0.0 9.5e-24 82.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain HALZ PF02183.13 EGO21063.1 - 0.12 12.0 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper G-gamma PF00631.17 EGO21064.1 - 2.4e-24 84.8 0.0 2.7e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain TRAM_LAG1_CLN8 PF03798.11 EGO21065.1 - 4.2e-28 98.2 19.9 4.9e-28 98.0 11.0 2.0 2 0 0 2 2 2 2 TLC domain Vps54 PF07928.7 EGO21066.1 - 4.6e-51 172.4 1.0 1.6e-50 170.7 0.7 2.0 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EGO21066.1 - 7.1e-08 31.7 0.0 1.9e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EGO21066.1 - 0.0012 18.6 0.4 0.0025 17.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) PPR PF01535.15 EGO21066.1 - 0.091 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 PPR repeat WD40 PF00400.27 EGO21068.1 - 3.1e-43 144.1 15.9 4e-09 36.0 0.2 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGO21068.1 - 0.0012 17.7 0.2 0.054 12.2 0.0 3.0 2 2 1 3 3 3 1 Coatomer WD associated region SGL PF08450.7 EGO21068.1 - 0.014 14.7 0.0 0.59 9.4 0.0 2.9 2 2 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Nup160 PF11715.3 EGO21068.1 - 0.16 10.0 3.4 0.11 10.6 0.1 2.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 ORC3_N PF07034.6 EGO21070.1 - 0.056 12.4 0.1 0.056 12.4 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Gliadin PF13016.1 EGO21070.1 - 0.098 12.8 5.5 0.14 12.3 3.8 1.3 1 0 0 1 1 1 0 Cys-rich Gliadin N-terminal Anophelin PF10731.4 EGO21070.1 - 2.2 8.4 5.7 3.1 7.9 4.0 1.2 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF4611 PF15387.1 EGO21070.1 - 3.1 8.0 5.4 4.9 7.3 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) WD40 PF00400.27 EGO21073.1 - 5.2e-45 149.7 17.5 2.7e-10 39.7 0.4 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat SGL PF08450.7 EGO21073.1 - 0.013 14.8 0.0 1.3 8.2 0.0 2.8 2 2 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Coatomer_WDAD PF04053.9 EGO21073.1 - 0.015 14.1 0.3 0.75 8.5 0.0 3.2 2 2 1 4 4 4 0 Coatomer WD associated region Nup160 PF11715.3 EGO21073.1 - 0.051 11.6 0.5 0.13 10.3 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cauli_VI PF01693.11 EGO21076.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin cwf18 PF08315.7 EGO21077.1 - 1.1e-29 103.5 9.7 1.1e-29 103.5 6.7 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor LepA_C PF06421.7 EGO21078.1 - 6.7e-42 141.7 0.1 1.2e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 EGO21078.1 - 4.6e-35 120.7 0.0 7.3e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGO21078.1 - 4.8e-16 58.3 0.0 9.8e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO21078.1 - 1.3e-06 28.4 0.1 2.5e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGO21078.1 - 2.1e-05 24.2 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EGO21078.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EGO21078.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EGO21078.1 - 0.097 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein IF-2B PF01008.12 EGO21079.1 - 7.8e-65 218.6 0.0 9.1e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1741 PF08427.5 EGO21079.1 - 0.23 10.8 1.7 0.25 10.7 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) Trp_syntA PF00290.15 EGO21080.1 - 6.8e-83 277.1 0.1 9.6e-83 276.6 0.1 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EGO21080.1 - 7.4e-45 153.4 0.2 1.4e-44 152.5 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 EGO21080.1 - 1.4e-05 24.5 0.1 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EGO21080.1 - 0.00031 20.0 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EGO21080.1 - 0.0054 16.0 0.2 0.098 11.8 0.1 2.3 2 0 0 2 2 2 1 PcrB family TMP-TENI PF02581.12 EGO21080.1 - 0.0061 15.7 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI PA PF02225.17 EGO21080.1 - 0.014 15.0 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 PA domain ThiG PF05690.9 EGO21080.1 - 0.02 14.0 0.8 0.14 11.1 0.2 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DFP PF04127.10 EGO21080.1 - 0.07 12.7 0.1 4.5 6.8 0.1 2.2 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein GP46 PF07409.7 EGO21080.1 - 0.14 11.4 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Phage protein GP46 Asparaginase PF00710.15 EGO21081.1 - 2.3e-114 381.5 0.0 2.7e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Asparaginase MAD PF05557.8 EGO21082.1 - 0.062 11.3 18.3 0.13 10.3 12.5 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein NPV_P10 PF05531.7 EGO21082.1 - 0.096 12.9 3.3 2.8 8.2 0.8 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 EGO21082.1 - 0.94 9.4 16.8 0.05 13.6 4.5 2.5 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 EGO21082.1 - 1.7 8.1 12.9 2.4 7.7 0.9 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) A_deaminase PF00962.17 EGO21083.1 - 9.1e-44 149.7 0.0 1.2e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase PF00962.17 EGO21084.1 - 2.6e-43 148.2 0.0 4.7e-43 147.3 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EGO21084.1 - 2.9e-05 23.9 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal KH_1 PF00013.24 EGO21085.1 - 1.7e-39 133.2 8.8 1.8e-14 53.1 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGO21085.1 - 6.4e-30 102.2 13.7 7.2e-10 38.2 0.9 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGO21085.1 - 6.6e-16 57.6 6.2 1.4e-05 24.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGO21085.1 - 1.5e-06 27.7 1.7 0.03 13.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGO21085.1 - 0.00052 19.7 4.8 2.8 7.8 0.0 3.5 3 0 0 3 3 3 3 NusA-like KH domain Brix PF04427.13 EGO21086.1 - 7.7e-38 130.0 0.0 1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain CPDase PF07823.6 EGO21088.1 - 2.1e-24 86.1 0.0 2.3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EGO21088.1 - 6.9e-10 38.8 0.0 9.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily TAXi_C PF14541.1 EGO21088.1 - 0.055 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal LigT_PEase PF02834.11 EGO21088.1 - 0.058 13.3 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase TMEM191C PF15194.1 EGO21089.1 - 0.031 14.1 0.1 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 TMEM191C family DUF1776 PF08643.5 EGO21091.1 - 3.1e-15 56.0 0.0 4.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Arginase PF00491.16 EGO21091.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Arginase family DUF1772 PF08592.6 EGO21092.1 - 0.34 10.6 8.7 2.4 7.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) RicinB_lectin_2 PF14200.1 EGO21093.1 - 1.7e-05 25.0 0.3 0.095 13.0 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like zf-CCHC PF00098.18 EGO21096.1 - 3.9e-08 32.8 1.1 5.7e-08 32.3 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO21096.1 - 0.028 14.0 0.3 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO21096.1 - 0.11 12.2 0.5 0.17 11.5 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO21096.1 - 0.82 9.4 3.0 0.6 9.8 0.7 1.8 2 0 0 2 2 2 0 Zinc knuckle PepSY_TM_1 PF13172.1 EGO21098.1 - 4.7 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix ATP-synt_ab PF00006.20 EGO21099.1 - 5.3e-63 212.3 0.0 1e-62 211.4 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO21099.1 - 4.6e-25 88.2 0.7 7.9e-25 87.5 0.5 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO21099.1 - 1.6e-22 79.4 1.5 1.6e-22 79.4 1.0 1.9 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 EGO21099.1 - 0.0052 15.6 0.8 0.029 13.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EGO21099.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGO21099.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EGO21099.1 - 0.025 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EGO21099.1 - 0.029 14.5 0.1 0.34 11.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGO21099.1 - 0.04 13.0 0.1 0.069 12.2 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EGO21099.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGO21099.1 - 0.042 13.5 0.2 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EGO21099.1 - 0.048 12.8 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO21099.1 - 0.051 13.5 0.1 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain GP40 PF11025.3 EGO21099.1 - 0.07 12.6 1.2 5.1 6.6 0.2 2.3 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Pyr_redox_2 PF07992.9 EGO21101.1 - 1.2e-23 84.0 0.0 1.7e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO21101.1 - 8.1e-12 45.3 0.1 1.2e-07 31.9 0.0 3.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EGO21101.1 - 3.5e-10 38.4 1.6 1.7e-05 23.7 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGO21101.1 - 1.3e-08 34.8 0.0 0.001 19.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO21101.1 - 2.4e-08 33.1 0.7 0.0021 17.7 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain Pyr_redox_3 PF13738.1 EGO21101.1 - 4.3e-07 30.2 0.0 0.039 14.0 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 EGO21101.1 - 9.8e-06 25.1 0.5 0.07 12.7 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO21101.1 - 2.5e-05 23.4 2.3 0.0047 16.1 0.5 2.7 2 0 0 2 2 2 2 EF hand NAD_binding_7 PF13241.1 EGO21101.1 - 0.13 12.5 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding EF-1_beta_acid PF10587.4 EGO21101.1 - 0.18 12.0 3.0 0.34 11.0 2.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region EF-hand_4 PF12763.2 EGO21101.1 - 0.3 10.8 2.2 6.2 6.6 0.4 2.4 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Clp1 PF06807.9 EGO21102.1 - 3.3e-20 72.6 0.0 3.8e-19 69.2 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGO21102.1 - 1.5e-06 28.0 0.0 5.4e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EGO21102.1 - 0.026 13.7 0.0 0.46 9.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO21102.1 - 0.086 12.8 0.0 0.64 9.9 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGO21102.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MFS_1 PF07690.11 EGO21103.1 - 1.6e-27 96.1 36.8 1.6e-27 96.1 25.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2867 PF11066.3 EGO21103.1 - 0.018 14.8 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) DUF2207 PF09972.4 EGO21103.1 - 0.94 7.9 10.8 2.8 6.4 0.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) AAA PF00004.24 EGO21104.1 - 7.7e-15 55.2 0.0 3.8e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO21104.1 - 9.2e-06 24.8 0.0 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EGO21104.1 - 1.2e-05 24.2 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGO21104.1 - 4.9e-05 23.0 0.0 0.00017 21.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EGO21104.1 - 0.00025 20.9 0.0 0.00092 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO21104.1 - 0.00025 21.1 0.0 0.0037 17.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO21104.1 - 0.00026 20.9 0.0 0.00058 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO21104.1 - 0.0004 21.1 0.0 0.0013 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO21104.1 - 0.0011 18.9 0.0 0.094 12.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EGO21104.1 - 0.0019 17.3 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EGO21104.1 - 0.0025 17.2 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGO21104.1 - 0.0073 15.7 0.2 0.62 9.4 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EGO21104.1 - 0.02 14.6 0.0 0.056 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGO21104.1 - 0.025 14.2 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EGO21104.1 - 0.027 14.2 0.2 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.1 EGO21104.1 - 0.036 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO21104.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO21104.1 - 0.085 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_2 PF07724.9 EGO21104.1 - 0.1 12.5 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Aminotran_1_2 PF00155.16 EGO21105.1 - 1.8e-14 53.4 0.0 2.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Arena_nucleocap PF00843.12 EGO21105.1 - 0.051 11.4 0.0 0.079 10.8 0.0 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein Pkinase PF00069.20 EGO21106.1 - 1.6e-53 181.4 0.0 2.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21106.1 - 9.3e-47 159.2 0.0 1.1e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO21106.1 - 0.0065 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SAP PF02037.22 EGO21106.1 - 0.039 13.4 0.3 0.081 12.4 0.2 1.6 1 0 0 1 1 1 0 SAP domain tRNA-synt_1c PF00749.16 EGO21108.1 - 2.6e-105 351.5 0.0 3.4e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGO21108.1 - 4.1e-38 130.7 0.1 6.7e-38 130.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.1 EGO21108.1 - 5.6e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21108.1 - 0.0003 21.2 0.5 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO21108.1 - 0.0047 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EGO21108.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Bot1p PF12298.3 EGO21109.1 - 1.1e-10 41.7 0.0 1.2e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein HMGL-like PF00682.14 EGO21111.1 - 3e-53 180.8 0.2 5.8e-39 134.1 0.0 2.3 1 1 1 2 2 2 2 HMGL-like LeuA_dimer PF08502.5 EGO21111.1 - 7.3e-47 158.5 0.0 2.4e-22 79.1 0.0 2.7 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain APG9 PF04109.11 EGO21112.1 - 3.7e-158 526.2 0.2 5e-158 525.8 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF3852 PF12963.2 EGO21112.1 - 0.81 9.7 6.0 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) EF-hand_4 PF12763.2 EGO21113.1 - 0.032 13.9 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF77 PF01910.12 EGO21114.1 - 1e-29 102.0 0.0 1.2e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EGO21114.1 - 2.2e-05 24.5 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DNA_methylase PF00145.12 EGO21115.1 - 2.1e-44 152.0 0.0 1.5e-43 149.2 0.0 2.3 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EGO21115.1 - 1.6e-18 66.5 2.9 2.6e-11 43.3 0.0 3.0 2 1 0 2 2 2 2 BAH domain P_proprotein PF01483.15 EGO21116.1 - 1.4e-30 104.9 1.0 2.7e-30 103.9 0.2 1.8 2 0 0 2 2 2 1 Proprotein convertase P-domain DUF2914 PF11141.3 EGO21116.1 - 0.00059 19.2 0.4 0.0015 18.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2914) MCM PF00493.18 EGO21117.1 - 4.7e-136 452.9 0.0 8.9e-135 448.7 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EGO21117.1 - 1.6e-26 93.1 1.6 3.6e-26 92.0 0.5 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EGO21117.1 - 1.8e-09 37.4 0.0 1.2e-06 28.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO21117.1 - 6.2e-08 32.0 0.1 1e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 EGO21117.1 - 0.00012 22.3 0.4 0.00044 20.6 0.3 2.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGO21117.1 - 0.028 14.0 0.0 0.093 12.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGO21117.1 - 0.078 12.4 0.1 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain POT1 PF02765.12 EGO21119.1 - 5.9e-05 23.0 0.0 7.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TAP42 PF04177.7 EGO21120.1 - 1e-74 251.5 0.3 1.2e-74 251.3 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family Med12-LCEWAV PF12145.3 EGO21120.1 - 0.005 15.3 0.4 0.0089 14.5 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Ras PF00071.17 EGO21121.1 - 1.5e-58 196.7 0.2 2.1e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21121.1 - 1.5e-22 80.2 0.1 3.1e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO21121.1 - 5.3e-16 58.3 0.1 7e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO21121.1 - 4.2e-07 29.3 0.3 5.4e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGO21121.1 - 5e-07 29.1 0.1 1.1e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGO21121.1 - 5.4e-07 29.2 0.2 4.2e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO21121.1 - 4e-06 26.7 0.2 1.9e-05 24.5 0.1 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO21121.1 - 0.00075 18.8 0.4 0.055 12.7 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGO21121.1 - 0.0063 16.3 0.0 0.86 9.4 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 EGO21121.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EGO21121.1 - 0.047 13.1 1.0 0.25 10.8 0.7 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.7 EGO21121.1 - 0.053 13.1 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EGO21121.1 - 0.059 13.0 0.3 4.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGO21121.1 - 0.062 13.1 0.5 0.13 12.2 0.2 1.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO21121.1 - 0.071 13.2 0.0 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain MTHFR PF02219.12 EGO21122.1 - 8.7e-108 359.7 0.0 1.5e-107 358.9 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Apc15p PF05841.6 EGO21123.1 - 1.1e-07 32.6 0.2 1.6e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Apc15p protein PNRC PF15365.1 EGO21123.1 - 0.03 14.3 0.4 0.067 13.2 0.3 1.7 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator LAT PF15234.1 EGO21123.1 - 0.045 13.2 3.3 0.052 13.0 2.3 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells ANAPC15 PF15243.1 EGO21123.1 - 1.6 8.8 17.1 0.73 9.9 3.7 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 15 WD40 PF00400.27 EGO21124.1 - 1.7e-13 49.8 15.4 0.00037 20.2 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGO21124.1 - 0.0078 14.5 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF2636 PF11120.3 EGO21124.1 - 0.091 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Transket_pyr PF02779.19 EGO21125.1 - 3.6e-41 140.5 0.1 4.9e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGO21125.1 - 6.2e-27 93.9 0.0 5.8e-26 90.8 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain DUF1029 PF06269.7 EGO21126.1 - 0.066 13.2 1.3 0.13 12.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) PI3_PI4_kinase PF00454.22 EGO21128.1 - 2e-36 125.6 0.2 3.1e-35 121.7 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGO21128.1 - 8.3e-22 77.2 0.0 3.8e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RdRP PF05183.7 EGO21129.1 - 1.7e-155 519.0 0.0 2.4e-155 518.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sipho_Gp157 PF05565.6 EGO21130.1 - 0.013 15.0 1.6 0.062 12.8 0.0 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF674 PF05056.7 EGO21130.1 - 0.051 12.2 2.3 0.26 9.8 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF674) Syntaxin_2 PF14523.1 EGO21130.1 - 0.084 12.9 4.4 0.2 11.7 0.7 2.1 1 1 1 2 2 2 0 Syntaxin-like protein Peptidase_M28 PF04389.12 EGO21131.1 - 1.7e-35 122.4 0.0 2.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 YebG PF07130.7 EGO21131.1 - 0.05 13.2 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 YebG protein Sybindin PF04099.7 EGO21132.1 - 2.2e-40 137.6 0.0 2.4e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGO21132.1 - 3.2e-09 36.7 0.0 3.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF1538 PF07556.6 EGO21132.1 - 0.025 13.6 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) HORMA PF02301.13 EGO21133.1 - 2.3e-28 99.1 0.0 4.7e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PFU PF09070.6 EGO21135.1 - 5.6e-42 142.4 0.1 1.2e-41 141.3 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EGO21135.1 - 6.8e-40 133.5 15.0 3.2e-08 33.1 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 EGO21135.1 - 1.7e-32 112.3 0.0 2.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EGO21135.1 - 3.8e-07 29.8 0.2 0.013 15.2 0.0 3.3 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region HpaP PF09483.5 EGO21135.1 - 5.9 6.8 6.4 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Type III secretion protein (HpaP) RVP_2 PF08284.6 EGO21141.1 - 1.8e-08 34.4 0.0 2e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO21141.1 - 1.8e-06 28.3 0.0 2.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO21141.1 - 5e-06 26.2 0.0 7.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2E PF12382.3 EGO21141.1 - 0.0012 18.6 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon peptidase zf-CCHC PF00098.18 EGO21142.1 - 4.6e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO21142.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO21142.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Transposase_28 PF04195.7 EGO21143.1 - 0.028 13.7 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative gypsy type transposon DUF3143 PF11341.3 EGO21145.1 - 0.008 16.0 0.5 0.01 15.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3143) MraZ PF02381.13 EGO21145.1 - 0.069 12.9 0.1 0.083 12.6 0.1 1.1 1 0 0 1 1 1 0 MraZ protein YTH PF04146.10 EGO21147.1 - 4.6e-47 159.1 0.7 8.3e-47 158.3 0.0 1.8 2 0 0 2 2 2 1 YT521-B-like domain UPF0261 PF06792.6 EGO21148.1 - 9.4e-145 482.0 1.4 1.1e-144 481.8 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 EGO21149.1 - 1.6e-132 440.5 0.5 1.9e-132 440.3 0.3 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EGO21149.1 - 0.00025 20.3 0.1 0.00039 19.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase AP_endonuc_2 PF01261.19 EGO21149.1 - 0.034 13.4 0.0 0.076 12.2 0.0 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Amidohydro_2 PF04909.9 EGO21149.1 - 0.071 12.6 0.0 0.32 10.4 0.0 2.1 1 1 0 1 1 1 0 Amidohydrolase Usp PF00582.21 EGO21149.1 - 0.1 12.7 1.0 1 9.5 0.1 2.3 2 1 0 2 2 2 0 Universal stress protein family WD40 PF00400.27 EGO21150.1 - 5e-78 254.4 15.4 4.2e-12 45.4 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO21150.1 - 2.3e-10 39.2 8.6 0.0094 14.1 0.0 5.8 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO21150.1 - 9.8e-08 31.1 2.2 0.42 9.3 0.1 4.3 2 2 2 4 4 4 3 Nup133 N terminal like eIF2A PF08662.6 EGO21150.1 - 0.00016 21.4 0.1 2.6 7.7 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EGO21150.1 - 0.00057 18.8 0.0 0.045 12.5 0.0 2.5 2 1 1 3 3 3 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 EGO21150.1 - 0.017 13.4 0.5 3 6.0 0.0 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1652 PF07865.6 EGO21150.1 - 0.051 13.1 0.0 79 2.9 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF1652) Kinesin PF00225.18 EGO21151.1 - 2.7e-80 269.6 0.3 2e-79 266.7 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain IncA PF04156.9 EGO21151.1 - 0.0036 16.9 5.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 IncA protein COG5 PF10392.4 EGO21151.1 - 0.12 12.3 3.7 2.6 8.0 0.1 2.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF4559 PF15112.1 EGO21151.1 - 0.31 10.1 2.5 0.22 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) V_ATPase_I PF01496.14 EGO21151.1 - 0.39 8.5 3.0 0.58 7.9 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EGO21151.1 - 0.51 10.7 9.9 3.1 8.1 0.3 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Spectrin PF00435.16 EGO21151.1 - 0.67 10.2 6.2 0.48 10.7 0.3 2.5 2 0 0 2 2 2 0 Spectrin repeat Peripla_BP_2 PF01497.13 EGO21151.1 - 1 8.4 4.5 18 4.3 0.1 3.0 2 1 1 3 3 3 0 Periplasmic binding protein DUF4201 PF13870.1 EGO21151.1 - 1.4 8.2 10.5 1.4 8.2 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 EGO21151.1 - 1.9 8.3 9.7 14 5.5 0.1 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 EGO21152.1 - 1.9e-05 24.1 6.9 1.9e-05 24.1 4.8 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Myosin_tail_1 PF01576.14 EGO21152.1 - 8.1e-05 20.5 18.6 9.6e-05 20.3 12.9 1.0 1 0 0 1 1 1 1 Myosin tail TMF_DNA_bd PF12329.3 EGO21152.1 - 0.0015 18.2 17.5 0.034 13.9 2.0 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.1 EGO21152.1 - 0.0016 17.8 19.9 0.011 15.1 8.8 2.1 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 EGO21152.1 - 0.0019 16.7 5.0 0.0019 16.7 3.5 1.5 1 1 0 1 1 1 1 AAA domain Macoilin PF09726.4 EGO21152.1 - 0.0025 16.1 16.1 0.0028 16.0 11.1 1.0 1 0 0 1 1 1 1 Transmembrane protein SlyX PF04102.7 EGO21152.1 - 0.0047 17.2 3.0 0.0047 17.2 2.1 2.8 1 1 2 3 3 3 1 SlyX IncA PF04156.9 EGO21152.1 - 0.0053 16.3 18.0 0.0073 15.9 12.2 1.5 1 1 0 1 1 1 1 IncA protein DUF1664 PF07889.7 EGO21152.1 - 0.0064 16.2 8.9 0.14 11.9 1.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EGO21152.1 - 0.0073 16.1 22.0 0.0093 15.8 9.2 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EGO21152.1 - 0.0083 15.3 2.9 0.011 14.9 2.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF641 PF04859.7 EGO21152.1 - 0.011 15.4 1.1 0.011 15.4 0.7 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 EGO21152.1 - 0.012 15.3 18.0 0.26 11.0 12.5 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EGO21152.1 - 0.014 14.3 20.0 0.24 10.2 13.1 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rac1 PF09632.5 EGO21152.1 - 0.029 13.4 3.9 0.057 12.4 1.0 2.0 1 1 2 3 3 3 0 Rac1-binding domain EzrA PF06160.7 EGO21152.1 - 0.032 12.4 8.6 0.024 12.8 4.6 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.4 EGO21152.1 - 0.034 12.9 11.0 0.044 12.5 7.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FliJ PF02050.11 EGO21152.1 - 0.072 13.1 15.6 1.9 8.5 6.2 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein COG2 PF06148.6 EGO21152.1 - 0.086 12.7 11.4 0.069 13.0 1.9 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IFP_35_N PF07334.8 EGO21152.1 - 0.1 12.5 0.3 0.1 12.5 0.2 3.1 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3407 PF11887.3 EGO21152.1 - 0.12 11.6 1.8 0.86 8.8 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3407) CCDC155 PF14662.1 EGO21152.1 - 0.13 11.8 19.8 0.032 13.8 11.1 1.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Baculo_PEP_C PF04513.7 EGO21152.1 - 0.14 12.0 5.5 0.38 10.5 2.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 EGO21152.1 - 0.18 11.6 1.1 1.3 8.8 0.0 2.7 3 1 0 3 3 2 0 Lipoprotein leucine-zipper MscS_porin PF12795.2 EGO21152.1 - 0.2 10.9 16.9 0.31 10.3 11.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 EGO21152.1 - 0.22 11.3 20.3 0.34 10.7 14.1 1.3 1 0 0 1 1 1 0 Tropomyosin like FliD_C PF07195.7 EGO21152.1 - 0.26 10.5 6.4 2.3 7.4 1.3 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus APG6 PF04111.7 EGO21152.1 - 0.26 10.2 14.0 0.38 9.7 9.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2450 PF10475.4 EGO21152.1 - 0.29 9.9 9.5 0.54 9.1 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EGO21152.1 - 0.3 9.6 16.3 0.85 8.2 11.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 EGO21152.1 - 0.58 7.4 17.4 0.78 6.9 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 EGO21152.1 - 0.62 9.4 19.1 0.25 10.7 7.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin PF00261.15 EGO21152.1 - 0.67 9.0 21.2 1.8 7.5 14.7 1.6 1 1 0 1 1 1 0 Tropomyosin Mod_r PF07200.8 EGO21152.1 - 0.69 9.8 14.6 0.35 10.7 7.1 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Lectin_N PF03954.9 EGO21152.1 - 0.73 9.2 8.1 1.8 7.9 0.8 2.3 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Sec20 PF03908.8 EGO21152.1 - 0.75 9.5 3.9 0.75 9.5 0.4 2.2 1 1 1 2 2 2 0 Sec20 ADIP PF11559.3 EGO21152.1 - 0.97 9.3 17.1 0.033 14.0 5.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EGO21152.1 - 1.1 8.3 16.8 1.7 7.7 11.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 EGO21152.1 - 1.2 9.4 9.6 3.6 7.9 2.9 3.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF4615 PF15393.1 EGO21152.1 - 1.3 9.2 6.4 2.3 8.4 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Syntaxin-6_N PF09177.6 EGO21152.1 - 1.4 9.3 9.8 2.1 8.8 3.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.4 EGO21152.1 - 1.5 8.8 15.0 1.8 8.5 8.6 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein LRS4 PF10422.4 EGO21152.1 - 1.5 8.1 11.3 2.4 7.4 7.5 1.6 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 Adeno_PIX PF03955.9 EGO21152.1 - 1.7 9.2 9.7 0.44 11.0 0.6 2.6 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) Med4 PF10018.4 EGO21152.1 - 1.7 7.9 13.2 0.62 9.4 2.0 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CorA PF01544.13 EGO21152.1 - 1.8 7.5 10.3 16 4.4 7.1 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Nup54 PF13874.1 EGO21152.1 - 1.8 8.1 16.4 1.9e+02 1.6 11.4 2.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.5 EGO21152.1 - 3.7 7.6 7.6 2.1 8.4 0.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 EGO21152.1 - 4.5 6.6 6.5 3.4 6.9 0.7 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4200 PF13863.1 EGO21152.1 - 4.7 7.1 22.4 1.9 8.4 7.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EGO21152.1 - 7.5 6.9 13.6 4.8 7.5 4.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 EGO21152.1 - 8.3 5.7 18.9 0.36 10.1 7.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Cluap1 PF10234.4 EGO21152.1 - 9.3 5.3 15.0 34 3.5 10.4 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 Mnd1 PF03962.10 EGO21152.1 - 9.6 5.8 20.0 1.9 8.1 6.9 2.2 1 1 1 2 2 2 0 Mnd1 family Med21 PF11221.3 EGO21152.1 - 9.6 6.1 17.0 0.97 9.4 2.6 2.4 1 1 1 2 2 2 0 Subunit 21 of Mediator complex adh_short_C2 PF13561.1 EGO21153.1 - 7.9e-31 107.6 0.1 9.3e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO21153.1 - 1.8e-24 86.5 0.1 2.8e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO21153.1 - 1.7e-11 44.1 0.0 3.6e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGO21153.1 - 0.00024 20.1 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGO21153.1 - 0.0017 17.8 0.0 0.0077 15.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GATA PF00320.22 EGO21154.1 - 6.2e-15 54.2 5.4 1.2e-14 53.3 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EGO21154.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EGO21154.1 - 0.00067 20.0 0.0 0.0015 18.8 0.0 1.6 1 1 0 1 1 1 1 PAS domain PAS PF00989.19 EGO21154.1 - 0.0013 18.5 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF4428 PF14471.1 EGO21154.1 - 0.11 12.2 1.0 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) WD40 PF00400.27 EGO21155.1 - 2.9e-21 74.4 21.7 2.4e-09 36.6 0.1 8.1 7 2 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EGO21155.1 - 4.8e-06 25.9 0.2 0.00073 18.8 0.0 2.3 2 0 0 2 2 2 2 Cortical protein marker for cell polarity DPPIV_N PF00930.16 EGO21155.1 - 0.0011 17.6 2.9 0.0091 14.6 1.1 2.6 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EGO21155.1 - 0.0016 18.2 0.3 0.98 9.0 0.0 3.1 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DASH_Dad3 PF08656.5 EGO21156.1 - 6.2e-21 73.8 0.0 7.9e-21 73.5 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 EGO21158.1 - 6.9e-53 179.4 0.0 8.4e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21158.1 - 6.9e-26 90.8 0.0 9e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO21158.1 - 6.7e-06 25.2 0.0 9.5e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO21158.1 - 0.015 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO21158.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ins_P5_2-kin PF06090.7 EGO21159.1 - 3.8e-58 196.9 0.0 4.4e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Acyl-CoA_dh_1 PF00441.19 EGO21160.1 - 8.7e-41 139.5 0.4 1.8e-40 138.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO21160.1 - 2.1e-36 124.9 0.0 3.8e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGO21160.1 - 5.9e-16 57.7 0.1 1.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO21160.1 - 2.2e-14 53.8 0.0 8e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EGO21160.1 - 0.03 14.6 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DUF996 PF06195.8 EGO21162.1 - 0.033 14.1 0.7 0.038 13.9 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF3366 PF11846.3 EGO21162.1 - 0.12 12.1 3.8 0.15 11.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Arginase PF00491.16 EGO21163.1 - 4.8e-77 258.9 0.2 5.6e-77 258.7 0.1 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.16 EGO21164.1 - 2e-30 106.0 0.0 2.3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II COesterase PF00135.23 EGO21166.1 - 1.9e-66 224.9 0.0 2.5e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO21166.1 - 1.6e-11 44.1 0.4 4.5e-11 42.7 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold NUDIX PF00293.23 EGO21167.1 - 4.1e-17 62.0 0.0 6.9e-16 58.1 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain WD40 PF00400.27 EGO21170.1 - 3.2e-74 242.3 15.6 2.5e-12 46.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGO21170.1 - 1.9e-10 40.7 0.0 7.5e-05 22.5 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGO21170.1 - 2.5e-06 25.9 2.7 0.009 14.1 0.0 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EGO21170.1 - 0.0042 15.9 0.1 0.15 10.8 0.0 2.3 1 1 0 2 2 2 1 Coatomer WD associated region IKI3 PF04762.7 EGO21170.1 - 0.16 9.7 0.1 0.52 8.0 0.0 1.8 2 1 0 2 2 2 0 IKI3 family Hira PF07569.6 EGO21170.1 - 0.17 11.0 0.3 26 3.9 0.0 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split PD40 PF07676.7 EGO21170.1 - 0.19 11.4 1.1 5 6.8 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NIF PF03031.13 EGO21171.1 - 5.5e-22 78.1 0.0 8.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EGO21171.1 - 9e-05 21.7 0.0 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PCI_Csn8 PF10075.4 EGO21172.1 - 1.9e-17 63.3 0.1 8.4e-17 61.2 0.1 2.1 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGO21172.1 - 0.0011 18.5 0.7 0.0019 17.8 0.5 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Glyco_hydro_57 PF03065.10 EGO21172.1 - 0.019 13.8 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF1681 PF07933.9 EGO21173.1 - 3.7e-51 172.8 0.0 4.3e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Glyco_hydro_6 PF01341.12 EGO21174.1 - 3.4e-110 368.1 1.7 4.2e-110 367.8 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EGO21174.1 - 2.1e-12 46.4 9.5 5.7e-12 45.0 6.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Aminotran_5 PF00266.14 EGO21175.1 - 1.1e-96 323.8 0.0 1.3e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGO21175.1 - 1.4e-06 27.6 0.2 3.9e-06 26.1 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGO21175.1 - 0.0036 15.6 0.1 0.0062 14.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 EGO21175.1 - 0.091 12.6 0.0 17 5.2 0.0 2.6 2 0 0 2 2 2 0 B12 binding domain RRM_1 PF00076.17 EGO21176.1 - 9.3e-28 95.6 0.0 4.3e-14 51.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO21176.1 - 9.2e-24 83.2 0.0 2.9e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO21176.1 - 7.3e-14 51.3 0.0 1.8e-06 27.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO21176.1 - 0.00053 19.7 0.0 0.0096 15.6 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGO21176.1 - 0.0047 16.6 1.5 0.27 11.0 0.0 2.7 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 EGO21176.1 - 0.021 14.6 0.0 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif CAP_GLY PF01302.20 EGO21177.1 - 8.7e-18 63.7 0.1 1.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EGO21177.1 - 1.1e-11 44.1 10.6 0.0006 19.3 0.0 5.9 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EGO21177.1 - 1.4e-05 24.7 0.1 7.7e-05 22.3 0.0 2.0 1 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EGO21177.1 - 0.0026 17.4 16.9 0.032 13.9 1.9 5.4 1 1 8 9 9 9 2 Leucine rich repeat LRR_7 PF13504.1 EGO21177.1 - 0.0097 15.9 6.6 44 4.9 0.1 6.0 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EGO21177.1 - 0.016 15.2 7.7 3.2 8.0 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Ubiquitin_2 PF14560.1 EGO21177.1 - 0.029 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain LRR_1 PF00560.28 EGO21177.1 - 0.048 13.6 12.2 23 5.5 0.0 6.8 6 1 1 7 7 7 0 Leucine Rich Repeat ECH_C PF13766.1 EGO21178.1 - 3.2e-31 107.9 0.0 9.1e-31 106.4 0.0 1.8 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGO21178.1 - 1.5e-26 93.0 0.0 2.5e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family IDO PF01231.13 EGO21180.1 - 2.1e-94 316.3 0.0 2.4e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.5 EGO21181.1 - 9.2e-50 168.1 1.9 5.6e-48 162.3 0.3 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EGO21181.1 - 1.9e-17 62.9 0.1 4.2e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EGO21181.1 - 2.1e-14 53.1 0.2 3.2e-13 49.3 0.1 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 EGO21181.1 - 0.026 14.6 0.1 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 DUF4539 PF15072.1 EGO21181.1 - 0.044 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) zf-AN1 PF01428.11 EGO21181.1 - 0.078 12.8 0.9 0.15 11.9 0.6 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger F-box-like PF12937.2 EGO21182.1 - 3.5e-07 29.8 0.2 9.7e-07 28.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO21182.1 - 0.007 15.9 0.6 1.2 8.8 0.0 3.3 3 0 0 3 3 3 1 F-box domain DivIC PF04977.10 EGO21182.1 - 0.013 14.9 0.0 0.6 9.6 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M16 PF00675.15 EGO21183.1 - 1.1e-31 109.6 0.1 7.3e-30 103.6 0.0 2.8 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO21183.1 - 1.4e-26 93.3 0.1 1.7e-12 47.4 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF3429 PF11911.3 EGO21184.1 - 5.5e-38 130.1 12.7 7.7e-38 129.6 8.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) AKAP28 PF14469.1 EGO21184.1 - 0.17 11.4 0.1 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 28 kDa A-kinase anchor WD40 PF00400.27 EGO21185.1 - 9.8e-30 101.3 15.6 1.4e-08 34.3 0.1 5.5 5 1 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EGO21185.1 - 0.014 15.6 0.5 13 6.2 0.2 3.6 3 0 0 3 3 3 0 PQQ-like domain SH3_9 PF14604.1 EGO21187.1 - 1.2e-13 50.3 0.0 2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO21187.1 - 1.1e-08 34.2 0.0 2.1e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EGO21187.1 - 4.2e-06 26.1 0.0 6.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SP2 PF03014.9 EGO21188.1 - 0.21 9.4 1.9 0.24 9.2 1.3 1.1 1 0 0 1 1 1 0 Structural protein 2 SKIP_SNW PF02731.10 EGO21189.1 - 1.3e-66 222.9 1.6 1.3e-66 222.9 1.1 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Spt5_N PF11942.3 EGO21189.1 - 7.7 7.2 22.9 0.96 10.1 6.1 3.6 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Tim54 PF11711.3 EGO21190.1 - 1.3e-69 234.6 0.0 2.7e-69 233.5 0.0 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF1320 PF07030.7 EGO21190.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) DEAD PF00270.24 EGO21191.1 - 9.9e-27 93.4 0.1 3.8e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sec63 PF02889.11 EGO21191.1 - 9e-19 67.8 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain ResIII PF04851.10 EGO21191.1 - 7.2e-10 39.0 0.1 2.1e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO21191.1 - 8.1e-05 22.4 0.5 0.0013 18.5 0.3 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGO21191.1 - 0.001 19.1 0.1 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGO21191.1 - 0.0034 16.3 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EGO21191.1 - 0.079 12.7 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EGO21191.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain CKS PF01111.14 EGO21192.1 - 2.5e-35 120.1 0.5 3.1e-35 119.8 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_S6 PF02395.11 EGO21193.1 - 0.048 11.7 0.0 0.048 11.7 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin A1 protease MnhB PF04039.8 EGO21195.1 - 1.9 8.5 9.9 0.34 10.9 0.1 2.7 1 1 2 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Lig_chan PF00060.21 EGO21195.1 - 2.7 7.6 4.9 6.4 6.4 3.3 1.8 1 1 0 1 1 1 0 Ligand-gated ion channel Peptidase_M16 PF00675.15 EGO21196.1 - 1e-38 132.4 1.9 1.4e-37 128.7 0.1 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO21196.1 - 1.1e-15 57.7 0.0 1.8e-06 27.7 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Retrotrans_gag PF03732.12 EGO21198.1 - 8.7e-06 25.7 0.1 1.9e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein MEDS PF14417.1 EGO21198.1 - 0.045 12.7 0.0 0.074 12.1 0.0 1.5 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Transglut_core PF01841.14 EGO21198.1 - 0.057 13.6 0.1 0.11 12.7 0.0 1.5 2 0 0 2 2 2 0 Transglutaminase-like superfamily RVP_2 PF08284.6 EGO21199.1 - 0.013 15.4 0.1 0.029 14.3 0.0 1.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Lipase_GDSL PF00657.17 EGO21200.1 - 8.2e-15 55.2 0.4 9.5e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Adap_comp_sub PF00928.16 EGO21201.1 - 2.2e-85 285.9 0.1 3.2e-85 285.3 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO21201.1 - 8.8e-07 28.7 2.5 1.5e-06 28.0 1.7 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SAPS PF04499.10 EGO21202.1 - 3.7e-129 431.4 0.0 5e-129 431.0 0.0 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein TPP_enzyme_N PF02776.13 EGO21203.1 - 3.3e-57 192.7 0.1 1e-56 191.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGO21203.1 - 2.6e-47 160.1 0.1 1e-45 155.0 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO21203.1 - 3.7e-37 127.1 1.0 8.4e-37 125.9 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PAP_assoc PF03828.14 EGO21204.1 - 9.2e-18 63.9 0.2 3.3e-17 62.1 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGO21204.1 - 8.2e-08 32.4 0.0 1.8e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pro_isomerase PF00160.16 EGO21207.1 - 6.4e-48 162.8 0.0 7.1e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGO21208.1 - 1.3e-57 189.7 25.9 6.2e-10 38.5 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGO21208.1 - 1.2e-11 44.1 2.3 3.1e-11 42.8 1.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO21208.1 - 8.7e-10 38.0 1.6 1.5e-09 37.2 0.8 1.7 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGO21208.1 - 5.4e-07 28.1 14.2 0.015 13.4 0.1 5.6 2 2 3 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGO21208.1 - 0.00059 19.3 2.1 0.83 9.0 0.2 3.1 2 1 1 3 3 3 3 PQQ-like domain Nucleoporin_N PF08801.6 EGO21208.1 - 0.00066 18.5 1.0 2.7 6.6 0.1 4.0 2 2 0 2 2 2 2 Nup133 N terminal like Nop14 PF04147.7 EGO21208.1 - 0.51 8.2 3.5 0.73 7.6 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 EGO21211.1 - 1.3e-20 73.4 0.5 2.1e-20 72.6 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO21211.1 - 6.8e-06 25.9 7.7 1.3e-05 25.0 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IER PF05760.7 EGO21214.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.8 3 0 0 3 3 3 0 Immediate early response protein (IER) GDA1_CD39 PF01150.12 EGO21215.1 - 1.8e-81 273.9 0.0 1.3e-69 234.8 0.0 3.1 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EGO21215.1 - 0.00054 19.2 0.0 0.0009 18.5 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Radical_SAM PF04055.16 EGO21216.1 - 3e-16 60.0 0.1 1e-15 58.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGO21216.1 - 3.2e-12 46.3 0.1 9e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO21216.1 - 0.015 15.3 0.0 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO21216.1 - 0.037 13.7 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Nuc_sug_transp PF04142.10 EGO21218.1 - 3.7e-76 255.4 4.4 5.2e-76 254.9 3.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EGO21218.1 - 7.3e-08 32.5 18.6 5.1e-07 29.8 4.3 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 EGO21218.1 - 1.6e-06 27.2 5.9 3e-06 26.3 4.1 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGO21218.1 - 3.7e-05 23.4 2.7 3.7e-05 23.4 1.9 3.4 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EGO21218.1 - 0.00019 21.4 3.9 0.00019 21.4 2.7 2.8 3 1 0 3 3 3 2 EamA-like transporter family DUF2404 PF10296.4 EGO21220.1 - 3e-05 24.0 0.0 0.0027 17.8 0.0 2.7 2 1 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) AAA_12 PF13087.1 EGO21221.1 - 1.4e-27 96.4 0.0 2.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EGO21221.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MFS_1 PF07690.11 EGO21223.1 - 2.8e-43 147.9 57.3 2e-42 145.2 39.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO21223.1 - 1.4e-15 56.8 10.9 1.4e-15 56.8 7.6 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGO21223.1 - 2.6e-07 29.2 18.1 3.7e-07 28.7 12.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF788 PF05620.6 EGO21223.1 - 1 9.1 3.6 1.5 8.6 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF788) LMF1 PF06762.9 EGO21225.1 - 0.26 10.0 1.4 0.26 10.0 1.0 1.0 1 0 0 1 1 1 0 Lipase maturation factor Y_phosphatase3 PF13350.1 EGO21227.1 - 3e-27 95.8 0.0 4.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21227.1 - 1.1e-13 51.1 0.3 8.6e-13 48.1 0.0 2.4 3 0 0 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO21227.1 - 5.7e-06 25.8 0.0 8.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO21227.1 - 5.8e-05 22.5 0.0 9.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGO21227.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EGO21227.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EGO21227.1 - 0.04 12.6 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain SNAPc19 PF15497.1 EGO21230.1 - 0.11 12.6 0.9 0.12 12.6 0.6 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 CVNH PF08881.5 EGO21232.1 - 4e-19 68.7 0.2 4.6e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 CVNH domain Y_phosphatase3 PF13350.1 EGO21234.1 - 7.5e-31 107.6 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21234.1 - 2.5e-20 72.3 0.1 2.4e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO21234.1 - 7.8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO21234.1 - 1.3e-05 24.6 0.0 1.8e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGO21234.1 - 0.0034 16.9 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO21234.1 - 0.0043 17.1 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.9 EGO21234.1 - 0.0046 15.7 0.0 0.0066 15.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGO21235.1 - 2.1e-29 102.9 0.0 3.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21235.1 - 6.6e-10 38.9 0.0 2.9e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO21235.1 - 8.9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO21235.1 - 9.8e-06 25.0 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGO21235.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO21235.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 EGO21235.1 - 0.016 14.0 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Tegument_dsDNA PF12818.2 EGO21235.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Metallophos PF00149.23 EGO21236.1 - 4.9e-10 39.1 1.4 9e-10 38.2 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO21236.1 - 1.5e-06 28.1 0.1 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2709 PF10915.3 EGO21236.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) tRNA_Me_trans PF03054.11 EGO21238.1 - 1e-113 379.5 0.0 1.2e-113 379.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EGO21238.1 - 0.12 11.2 0.0 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 NAD synthase Asn_synthase PF00733.16 EGO21238.1 - 0.14 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase CENP-C_C PF11699.3 EGO21239.1 - 7.6e-27 93.1 0.0 1.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EGO21239.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Tyr_Deacylase PF02580.11 EGO21241.1 - 2.9e-51 173.2 0.1 3.5e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PLDc_2 PF13091.1 EGO21242.1 - 5.6e-09 35.8 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGO21242.1 - 6.3e-07 28.9 0.7 0.0057 16.4 0.1 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif zf-C3HC4_3 PF13920.1 EGO21243.1 - 9.4e-08 31.6 16.9 9.4e-08 31.6 11.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Cyclin PF08613.6 EGO21245.1 - 1.2e-11 45.1 0.4 2.5e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGO21245.1 - 1.2e-09 37.8 0.0 1.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF566 PF04484.7 EGO21245.1 - 2.7 7.4 10.3 4.8 6.5 7.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-C4H2 PF10146.4 EGO21246.1 - 1.1e-06 28.9 1.2 1.6e-06 28.3 0.8 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein TBPIP PF07106.8 EGO21246.1 - 0.014 14.9 5.8 0.014 14.9 4.0 1.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 EGO21246.1 - 0.065 12.9 3.2 0.11 12.1 2.2 1.4 1 0 0 1 1 1 0 Laminin Domain II RibD_C PF01872.12 EGO21247.1 - 3.4e-34 118.2 0.0 4.2e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Rad21_Rec8_N PF04825.8 EGO21248.1 - 9.7e-17 60.9 0.0 2.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGO21248.1 - 9.5e-07 27.9 0.0 2.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WWamide PF08258.6 EGO21259.1 - 4 7.9 4.7 13 6.4 0.1 2.6 3 0 0 3 3 3 0 WWamide peptide MHC_I_2 PF14586.1 EGO21262.1 - 0.064 12.8 0.1 0.078 12.5 0.1 1.1 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Lentiviral_Tat PF02998.9 EGO21262.1 - 0.27 11.1 2.0 0.5 10.2 0.3 2.1 2 1 0 2 2 2 0 Lentiviral Tat protein Gtr1_RagA PF04670.7 EGO21263.1 - 2.6e-86 288.5 0.1 4.8e-86 287.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGO21263.1 - 3.7e-07 29.5 0.8 1.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EGO21263.1 - 5.3e-07 29.1 0.0 9.2e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21263.1 - 5e-06 26.9 0.1 0.00015 22.1 0.0 2.6 2 1 1 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 EGO21263.1 - 1.2e-05 25.2 0.0 4.4e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase MAD PF05557.8 EGO21263.1 - 0.0074 14.4 0.4 0.012 13.6 0.3 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein PduV-EutP PF10662.4 EGO21263.1 - 0.015 14.7 0.0 0.084 12.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGO21263.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGO21263.1 - 0.034 14.2 0.2 1.1 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain HALZ PF02183.13 EGO21263.1 - 0.042 13.5 0.1 0.094 12.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper cobW PF02492.14 EGO21263.1 - 0.048 13.1 0.1 14 5.1 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EGO21263.1 - 0.091 12.3 0.4 0.19 11.2 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EGO21263.1 - 0.097 12.8 0.2 8.2 6.6 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PRESAN PF09687.5 EGO21263.1 - 0.12 12.4 0.2 9 6.3 0.0 2.4 2 1 0 2 2 2 0 Plasmodium RESA N-terminal Tyrosinase PF00264.15 EGO21265.1 - 1.4e-39 136.5 0.2 2.3e-39 135.8 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Na_Ca_ex PF01699.19 EGO21266.1 - 2.5e-42 143.8 30.3 8.2e-25 87.0 7.4 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EGO21266.1 - 3.5 7.5 6.3 1.1 9.1 0.4 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Septin PF00735.13 EGO21269.1 - 3.3e-115 383.9 0.9 3.8e-115 383.7 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGO21269.1 - 9.5e-08 32.0 0.0 3.1e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO21269.1 - 5.7e-06 25.5 0.0 1.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EGO21269.1 - 7.5e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGO21269.1 - 2.4e-05 23.8 0.4 0.00088 18.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EGO21269.1 - 0.00024 20.6 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGO21269.1 - 0.00034 20.4 0.4 0.71 9.6 0.1 2.4 1 1 1 2 2 2 2 Dynamin family T2SE PF00437.15 EGO21269.1 - 0.00048 19.1 0.1 0.00091 18.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Gtr1_RagA PF04670.7 EGO21269.1 - 0.0035 16.5 0.1 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EGO21269.1 - 0.0039 17.4 0.6 0.0067 16.7 0.3 1.7 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EGO21269.1 - 0.0043 16.5 0.2 0.0053 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 EGO21269.1 - 0.012 14.5 0.1 0.029 13.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 EGO21269.1 - 0.015 15.6 0.0 0.023 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EGO21269.1 - 0.022 15.2 0.0 0.061 13.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DEAD PF00270.24 EGO21269.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EGO21269.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGO21269.1 - 0.037 13.9 0.2 0.25 11.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGO21269.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGO21269.1 - 0.045 13.8 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EGO21269.1 - 0.06 12.1 0.5 0.18 10.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) E1-E2_ATPase PF00122.15 EGO21270.1 - 4e-14 52.1 0.1 4e-14 52.1 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EGO21270.1 - 1.2e-13 51.6 0.3 8.1e-13 48.9 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO21270.1 - 1.8e-13 51.4 1.2 7.2e-08 33.1 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO21270.1 - 4.9e-11 42.4 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO21270.1 - 0.00019 21.1 0.2 0.0046 16.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VRR_NUC PF08774.6 EGO21273.1 - 1.8e-18 66.3 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 VRR-NUC domain Sugarporin_N PF11471.3 EGO21273.1 - 0.93 9.1 5.3 9.8 5.9 0.7 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension HNH_2 PF13391.1 EGO21274.1 - 0.003 17.3 0.0 0.008 15.9 0.0 1.8 1 1 0 1 1 1 1 HNH endonuclease Abi PF02517.11 EGO21276.1 - 0.32 11.1 3.9 0.36 11.0 2.7 1.1 1 0 0 1 1 1 0 CAAX protease self-immunity WD40 PF00400.27 EGO21277.1 - 0.00074 19.3 6.8 0.0034 17.1 0.4 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat bZIP_2 PF07716.10 EGO21277.1 - 0.19 11.5 5.5 0.083 12.7 0.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.20 EGO21278.1 - 6e-54 182.9 0.0 7.1e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21278.1 - 1.1e-39 136.1 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO21278.1 - 0.00056 18.9 0.0 0.004 16.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO21278.1 - 0.052 12.5 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 EGO21280.1 - 2.6e-45 153.9 0.0 7.2e-45 152.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGO21280.1 - 6.4e-26 89.6 0.1 1.2e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGO21280.1 - 4.4e-20 71.3 0.1 1.9e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO21281.1 - 1.1e-44 152.3 0.0 7.5e-36 123.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO21281.1 - 9.7e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO21281.1 - 0.0011 18.5 0.0 0.0042 16.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AKNA PF12443.3 EGO21281.1 - 0.099 12.6 3.7 0.071 13.1 0.6 2.3 3 0 0 3 3 3 0 AT-hook-containing transcription factor Acetyltransf_1 PF00583.19 EGO21282.1 - 2.8e-09 36.8 0.0 4.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO21282.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO21282.1 - 0.00074 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO21282.1 - 0.028 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO21282.1 - 0.041 13.7 0.5 0.13 12.1 0.4 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3608 PF12257.3 EGO21283.1 - 9.7e-65 218.2 0.0 1.4e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGO21283.1 - 2.4e-16 59.2 0.1 5.1e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3357 PF11837.3 EGO21284.1 - 0.011 15.5 0.9 0.016 15.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Epiglycanin_TR PF05647.6 EGO21284.1 - 0.16 11.8 3.9 0.3 10.9 2.7 1.5 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like COX15-CtaA PF02628.10 EGO21285.1 - 0.034 13.0 2.1 0.051 12.4 1.1 1.3 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein COPI_assoc PF08507.5 EGO21285.1 - 0.23 11.1 7.5 3.8 7.1 5.1 2.2 1 1 0 1 1 1 0 COPI associated protein DUF836 PF05768.9 EGO21286.1 - 5.1e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-CCHC PF00098.18 EGO21286.1 - 0.00071 19.3 0.7 0.0013 18.5 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO21286.1 - 0.069 12.8 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle AAA_5 PF07728.9 EGO21287.1 - 5.3e-12 45.6 0.0 9.6e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO21287.1 - 8.4e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGO21287.1 - 2.5e-06 27.7 0.0 5.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO21287.1 - 2.8e-06 27.4 0.2 0.00011 22.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO21287.1 - 4.8e-06 26.7 0.0 2.2e-05 24.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_PrkA PF08298.6 EGO21287.1 - 0.00015 20.5 0.0 0.00054 18.7 0.0 1.7 2 0 0 2 2 2 1 PrkA AAA domain Mg_chelatase PF01078.16 EGO21287.1 - 0.00043 19.5 0.2 0.0068 15.5 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGO21287.1 - 0.0021 18.1 0.0 0.0067 16.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase Zeta_toxin PF06414.7 EGO21287.1 - 0.0036 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGO21287.1 - 0.0053 16.6 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.2 EGO21287.1 - 0.0055 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_14 PF13173.1 EGO21287.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO21287.1 - 0.025 15.3 0.0 0.061 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGO21287.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Ank PF00023.25 EGO21287.1 - 0.048 13.4 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat RuvB_N PF05496.7 EGO21287.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGO21287.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EGO21287.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SH3_9 PF14604.1 EGO21288.1 - 6e-08 32.1 0.0 1.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO21288.1 - 4.4e-07 29.1 0.0 7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO21288.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pam17 PF08566.5 EGO21289.1 - 1.5e-62 210.3 0.0 1.9e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Helicase_C PF00271.26 EGO21290.1 - 8.2e-19 67.2 0.0 1.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO21290.1 - 2.8e-18 65.9 0.0 7.8e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO21290.1 - 8.2e-18 64.8 0.0 2e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2413 PF10310.4 EGO21291.1 - 7.4e-62 209.6 6.2 2.8e-61 207.7 4.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) PCI PF01399.22 EGO21293.1 - 7.1e-18 64.8 0.5 2.8e-17 62.9 0.4 2.1 1 0 0 1 1 1 1 PCI domain DDRGK PF09756.4 EGO21293.1 - 0.00014 21.3 0.3 0.00026 20.4 0.2 1.4 1 0 0 1 1 1 1 DDRGK domain DDE_Tnp_1_assoc PF13808.1 EGO21293.1 - 0.043 13.4 0.3 0.56 9.9 0.0 2.6 3 0 0 3 3 3 0 DDE_Tnp_1-associated TPR_6 PF13174.1 EGO21293.1 - 7.5 7.2 7.2 21 5.8 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EGO21294.1 - 8.6e-51 171.8 0.3 1.2e-50 171.3 0.2 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGO21294.1 - 1.9e-16 60.2 0.0 5.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain Y_phosphatase2 PF03162.8 EGO21295.1 - 0.024 14.0 0.1 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family ABC_tran PF00005.22 EGO21296.1 - 1.8e-21 76.8 0.0 3.4e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO21296.1 - 1.4e-10 41.6 0.3 0.00098 19.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EGO21296.1 - 1.4e-07 30.9 0.1 0.0024 17.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EGO21296.1 - 5.8e-05 22.9 0.4 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGO21296.1 - 0.0027 17.8 0.0 0.61 10.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGO21296.1 - 0.0061 16.5 1.1 0.06 13.3 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGO21296.1 - 0.017 15.9 0.0 0.043 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGO21296.1 - 0.019 14.5 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO21296.1 - 0.036 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EGO21296.1 - 0.068 12.8 0.0 0.42 10.2 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EGO21296.1 - 0.069 12.5 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EGO21296.1 - 0.083 13.2 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGO21296.1 - 0.091 12.2 0.0 2.2 7.7 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EGO21296.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO21296.1 - 0.12 11.7 0.0 0.74 9.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain zf-C2H2_4 PF13894.1 EGO21298.1 - 0.007 16.6 2.1 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO21298.1 - 0.022 15.0 0.0 0.022 15.0 0.0 2.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.2 EGO21299.1 - 3.9e-08 33.4 0.1 2.1e-07 31.0 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO21299.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_4 PF13147.1 EGO21300.1 - 5.2e-28 98.8 0.7 1.5e-25 90.8 0.1 3.2 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO21300.1 - 2.7e-13 50.2 0.2 1.5e-08 34.6 0.0 3.9 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO21300.1 - 1.1e-12 47.5 1.4 4.9e-09 35.8 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EGO21300.1 - 3.4e-08 33.1 1.4 2.6e-06 26.9 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family AP_endonuc_2 PF01261.19 EGO21301.1 - 5.4e-30 104.2 0.0 1.3e-29 103.0 0.0 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.20 EGO21302.1 - 1e-62 211.6 0.0 2.3e-62 210.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21302.1 - 3.1e-36 124.7 0.0 1.6e-22 79.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO21302.1 - 3.8e-06 26.0 0.0 9.6e-06 24.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO21302.1 - 2.1e-05 24.3 3.1 0.024 14.3 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Formyl_trans_N PF00551.14 EGO21305.1 - 1.9e-36 125.2 0.0 4.8e-17 62.0 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase HLH PF00010.21 EGO21307.1 - 1.8e-11 43.5 0.5 3.7e-11 42.5 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_42M PF08532.5 EGO21308.1 - 0.024 13.7 0.0 0.026 13.6 0.0 1.0 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain zf-C2H2_4 PF13894.1 EGO21311.1 - 0.025 14.8 1.7 0.11 12.8 1.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1772 PF08592.6 EGO21320.1 - 0.28 10.9 3.9 0.12 12.1 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1326 PF07040.6 EGO21321.1 - 0.15 11.8 5.7 0.26 11.0 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) MBOAT_2 PF13813.1 EGO21322.1 - 2.7e-13 49.8 5.2 2.7e-13 49.8 3.6 3.4 2 1 1 3 3 3 1 Membrane bound O-acyl transferase family ATP-synt_J PF04911.7 EGO21323.1 - 1.6e-19 69.0 0.2 2.1e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 ATP synthase j chain DUF4419 PF14388.1 EGO21324.1 - 3.8e-83 279.1 0.0 4.5e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.1 EGO21326.1 - 6.7e-103 344.0 0.0 8.1e-103 343.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4419 PF14388.1 EGO21327.1 - 3.6e-15 55.9 0.0 4.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Y_phosphatase3 PF13350.1 EGO21328.1 - 6.5e-34 117.5 0.0 8.6e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21328.1 - 1.6e-06 28.0 0.0 4.8e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGO21328.1 - 2.9e-05 23.4 0.0 4.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO21328.1 - 8.1e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGO21328.1 - 0.011 15.3 0.0 0.066 12.7 0.0 2.2 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EGO21328.1 - 0.07 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF4381 PF14316.1 EGO21329.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Retrotrans_gag PF03732.12 EGO21332.1 - 1.5e-05 24.9 0.1 1.5e-05 24.9 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Alpha_kinase PF02816.13 EGO21335.1 - 8.6e-11 41.8 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Flg_hook PF02120.11 EGO21335.1 - 0.1 12.3 0.1 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Y_phosphatase3 PF13350.1 EGO21337.1 - 1.7e-26 93.4 0.0 2.5e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EGO21337.1 - 7.6e-06 25.3 0.0 9.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21337.1 - 1.9e-05 24.6 0.0 5.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO21337.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGO21337.1 - 0.01 15.3 0.0 0.033 13.7 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO21337.1 - 0.018 15.0 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 EGO21337.1 - 0.022 13.5 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Clathrin PF00637.15 EGO21338.1 - 1.2e-18 67.1 1.4 2.8e-13 49.6 0.2 2.7 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.3 EGO21338.1 - 6.7e-07 29.0 0.2 2.7e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal TPR_11 PF13414.1 EGO21338.1 - 0.013 15.0 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 0 TPR repeat zf-RING_5 PF14634.1 EGO21338.1 - 0.053 13.2 7.4 0.091 12.5 5.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.12 EGO21338.1 - 0.091 12.7 0.1 1.5 8.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO21338.1 - 0.13 13.0 0.3 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EGO21338.1 - 0.24 11.4 7.5 0.44 10.6 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO21338.1 - 0.28 11.0 7.8 0.54 10.1 5.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 EGO21338.1 - 1.1 9.4 6.3 2.2 8.4 4.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGO21338.1 - 5.2 6.8 8.0 9.5 5.9 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COX16 PF14138.1 EGO21339.1 - 2.9e-28 97.8 0.1 3.7e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Adenylsucc_synt PF00709.16 EGO21340.1 - 5e-160 532.7 0.0 5.7e-160 532.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Lipocalin_5 PF13924.1 EGO21342.1 - 0.014 15.1 0.1 0.05 13.2 0.0 2.0 2 0 0 2 2 2 0 Lipocalin-like domain DDE_1 PF03184.14 EGO21343.1 - 2.2e-13 49.8 0.0 4.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO21343.1 - 0.0003 20.5 0.0 0.00087 19.0 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease RbsD_FucU PF05025.8 EGO21344.1 - 0.048 13.9 0.9 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family ABC_membrane PF00664.18 EGO21346.1 - 5.7e-53 180.0 33.0 1.7e-30 106.4 6.8 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO21346.1 - 1.5e-49 167.8 0.1 1.1e-27 96.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO21346.1 - 1.3e-07 31.8 0.9 0.13 12.1 0.1 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EGO21346.1 - 1.4e-06 27.7 6.2 0.00018 20.7 1.6 3.6 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGO21346.1 - 3e-06 26.7 0.0 0.022 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO21346.1 - 7.1e-06 26.1 0.1 0.026 14.5 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGO21346.1 - 1.3e-05 25.0 1.0 0.027 14.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO21346.1 - 1.7e-05 24.2 0.8 0.023 14.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EGO21346.1 - 1.8e-05 24.3 0.0 0.071 12.6 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 EGO21346.1 - 2e-05 25.0 0.6 0.13 12.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EGO21346.1 - 3.6e-05 24.1 0.5 0.42 10.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGO21346.1 - 4.9e-05 22.5 0.5 0.3 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO21346.1 - 0.00064 20.5 0.1 0.12 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGO21346.1 - 0.0031 17.0 0.2 0.45 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain TrwB_AAD_bind PF10412.4 EGO21346.1 - 0.01 14.4 2.4 0.81 8.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 EGO21346.1 - 0.011 15.3 2.3 0.042 13.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EGO21346.1 - 0.018 14.1 3.6 2.1 7.3 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EGO21346.1 - 0.02 14.6 2.8 2.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 EGO21346.1 - 0.025 14.1 3.9 4.7 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO21346.1 - 0.065 12.6 0.1 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EGO21346.1 - 0.068 12.6 2.1 0.63 9.4 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EGO21346.1 - 0.078 12.6 1.6 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGO21346.1 - 0.088 12.3 3.1 33 3.9 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EGO21346.1 - 0.093 13.0 0.1 18 5.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 EGO21346.1 - 0.13 12.4 4.8 7.3 6.7 0.2 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EGO21346.1 - 0.15 11.8 5.0 0.1 12.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EGO21346.1 - 0.26 10.9 4.0 0.64 9.6 0.8 2.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EGO21346.1 - 0.73 9.7 2.1 39 4.0 0.2 3.1 3 0 0 3 3 3 0 AAA domain Retrotrans_gag PF03732.12 EGO21349.1 - 3.3e-08 33.4 0.2 3.3e-08 33.4 0.2 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO21349.1 - 3.5e-08 33.0 5.1 8.4e-08 31.7 3.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO21349.1 - 4.9 6.9 6.9 0.52 10.0 1.2 2.0 2 0 0 2 2 2 0 Zinc knuckle DMRL_synthase PF00885.14 EGO21350.1 - 1.9e-48 163.7 0.1 4.1e-27 94.6 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Choline_transpo PF04515.7 EGO21351.1 - 4.4e-22 78.2 11.2 2.4e-21 75.8 7.5 2.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter Shisa PF13908.1 EGO21351.1 - 0.022 14.9 0.9 0.022 14.9 0.6 2.5 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator MAPEG PF01124.13 EGO21352.1 - 6e-19 67.9 0.6 7.4e-19 67.6 0.4 1.1 1 0 0 1 1 1 1 MAPEG family Ribosomal_L37 PF08561.5 EGO21353.1 - 2.6e-22 78.1 0.0 3.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 WD40 PF00400.27 EGO21354.1 - 1.5e-07 31.0 4.7 0.23 11.4 0.2 5.5 4 1 0 4 4 4 4 WD domain, G-beta repeat ADH_zinc_N PF00107.21 EGO21355.1 - 2.3e-22 78.9 1.0 4.5e-22 77.9 0.5 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO21355.1 - 7.1e-11 43.0 0.1 1.2e-10 42.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO21355.1 - 6e-05 22.7 0.1 0.0013 18.4 0.0 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Talin_middle PF09141.5 EGO21355.1 - 0.13 11.9 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Talin, middle domain Retrotrans_gag PF03732.12 EGO21357.1 - 7.6e-08 32.3 0.1 7.6e-08 32.3 0.1 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO21357.1 - 0.0025 17.6 1.0 0.0025 17.6 0.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO21360.1 - 8.1e-07 28.6 1.6 8.9e-07 28.5 1.1 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO21360.1 - 1.8e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO21360.1 - 0.11 12.0 4.1 0.15 11.6 2.8 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4606 PF15379.1 EGO21360.1 - 0.89 9.6 3.0 1.6 8.8 2.0 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) DUF4381 PF14316.1 EGO21361.1 - 0.055 13.5 0.2 0.059 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PMT PF02366.13 EGO21364.1 - 6.7e-77 258.1 19.8 6.7e-77 258.1 13.7 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGO21364.1 - 7.7e-30 103.8 1.1 1.2e-29 103.2 0.8 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EGO21364.1 - 0.018 14.9 22.1 0.049 13.5 9.6 2.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase RRP7 PF12923.2 EGO21365.1 - 3.2e-32 111.2 4.2 3.2e-32 111.2 2.9 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EGO21365.1 - 0.00017 21.1 0.1 0.0078 15.8 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO21365.1 - 0.0062 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bacillus_HBL PF05791.6 EGO21366.1 - 0.012 15.0 0.8 0.11 11.9 0.1 2.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF945 PF06097.6 EGO21366.1 - 0.042 12.6 1.5 0.068 11.9 1.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) DUF1664 PF07889.7 EGO21366.1 - 0.12 12.1 8.3 15 5.4 0.1 4.6 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) YvrJ PF12841.2 EGO21366.1 - 0.2 10.9 0.8 7.5 5.9 0.0 3.5 3 0 0 3 3 3 0 YvrJ protein family BLOC1_2 PF10046.4 EGO21366.1 - 0.79 9.9 5.7 10 6.2 0.1 4.2 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EGO21366.1 - 2.8 6.3 11.5 2.9 6.2 2.6 2.9 2 1 1 3 3 3 0 AAA domain Lectin_N PF03954.9 EGO21366.1 - 9.3 5.6 10.7 10 5.5 2.0 3.1 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Abhydrolase_6 PF12697.2 EGO21367.1 - 5.7e-24 85.2 0.1 7.1e-24 84.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO21367.1 - 1.4e-13 50.8 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO21367.1 - 6.1e-13 48.8 0.0 2.5e-12 46.8 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGO21367.1 - 0.0026 17.2 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EGO21367.1 - 0.0037 17.0 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EGO21367.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIP PF03583.9 EGO21367.1 - 0.075 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.16 EGO21367.1 - 0.097 11.8 0.0 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family AKAP2_C PF15304.1 EGO21368.1 - 0.015 14.9 4.3 0.018 14.6 3.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus CAP_N PF01213.14 EGO21368.1 - 0.94 8.7 3.9 0.82 8.8 2.1 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Retrotrans_gag PF03732.12 EGO21369.1 - 0.01 15.8 0.5 0.019 15.0 0.3 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.18 EGO21369.1 - 0.011 15.6 1.8 0.018 14.9 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.24 EGO21370.1 - 9.9e-43 145.5 2.4 3e-42 143.9 0.5 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO21370.1 - 7.1e-27 93.0 0.3 2.7e-26 91.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO21370.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO21370.1 - 0.002 17.8 0.2 0.0068 16.1 0.0 2.0 1 1 1 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGO21370.1 - 0.0061 16.1 0.2 0.019 14.5 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO21370.1 - 0.0077 16.3 0.2 0.037 14.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EGO21370.1 - 0.027 14.2 0.0 0.15 11.7 0.0 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF1253 PF06862.7 EGO21370.1 - 0.033 12.5 0.1 1.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_RecD PF05127.9 EGO21370.1 - 0.039 13.5 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.1 EGO21370.1 - 0.069 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.20 EGO21370.1 - 0.094 11.8 0.1 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Ras PF00071.17 EGO21371.1 - 3.6e-51 172.7 0.0 4.2e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21371.1 - 1e-15 58.2 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO21371.1 - 2.6e-12 46.3 0.0 3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO21371.1 - 1.1e-05 25.0 0.0 0.0003 20.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO21371.1 - 0.0017 18.2 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP-synt_Eps PF04627.8 EGO21372.1 - 8.4e-22 76.4 3.8 1.3e-21 75.8 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Sialidase PF02973.11 EGO21373.1 - 0.014 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Sialidase, N-terminal domain COX4 PF02936.9 EGO21374.1 - 9.8e-36 122.6 0.0 1.2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.5 EGO21374.1 - 0.28 10.8 1.8 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Putative addiction module component HMG_box_2 PF09011.5 EGO21374.1 - 0.71 10.2 3.1 0.89 9.9 0.5 2.1 2 0 0 2 2 2 0 HMG-box domain MitMem_reg PF13012.1 EGO21375.1 - 2.2e-36 124.4 0.3 4.1e-36 123.5 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGO21375.1 - 2.2e-26 91.8 0.0 4e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF336 PF03928.9 EGO21377.1 - 2.5e-21 75.8 0.0 3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Zn_clus PF00172.13 EGO21378.1 - 1.1e-08 34.7 10.5 2.4e-08 33.7 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EGO21379.1 - 3.1e-30 104.1 0.4 1.5e-29 101.8 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO21379.1 - 1.1e-13 50.8 1.0 4e-10 39.3 0.0 3.0 2 1 0 3 3 3 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO21379.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EGO21379.1 - 0.039 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGO21379.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Hemerythrin PF01814.18 EGO21380.1 - 0.00025 21.2 0.5 0.00043 20.4 0.4 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AMP-binding PF00501.23 EGO21383.1 - 2e-159 530.4 0.1 2.5e-87 292.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGO21383.1 - 4.1e-86 288.5 0.0 2.5e-42 144.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGO21383.1 - 2.8e-23 81.9 0.8 2.2e-08 34.2 0.1 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGO21383.1 - 8.3e-09 36.2 0.1 0.0022 18.9 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGO21383.1 - 8.6e-09 35.5 0.0 3.5e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 HxxPF-repeated domain p450 PF00067.17 EGO21384.1 - 3.4e-44 151.1 0.0 4.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SHOCT PF09851.4 EGO21384.1 - 0.043 13.3 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain MFS_1 PF07690.11 EGO21385.1 - 8.7e-29 100.3 53.8 1e-22 80.3 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 EGO21385.1 - 2 7.8 3.4 2 7.8 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) p450 PF00067.17 EGO21387.1 - 3.3e-46 157.7 0.0 4.4e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF382 PF04037.8 EGO21389.1 - 2e-60 202.2 0.2 6.1e-60 200.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EGO21389.1 - 6.2e-19 67.1 6.6 1.2e-18 66.1 4.6 1.5 1 0 0 1 1 1 1 PSP Arrestin_C PF02752.17 EGO21390.1 - 3.2e-09 37.0 0.0 9.4e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGO21390.1 - 5.2e-07 29.5 0.1 3.7e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EGO21390.1 - 0.00019 20.9 0.0 0.006 16.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like Myc-LZ PF02344.10 EGO21391.1 - 5.4 6.7 10.5 2.6 7.7 1.4 2.6 3 0 0 3 3 3 0 Myc leucine zipper domain PSDC PF12588.3 EGO21392.1 - 6.2e-42 142.5 0.0 9e-42 142.0 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EGO21392.1 - 4.2e-34 117.6 0.1 7.6e-34 116.7 0.1 1.4 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 EGO21392.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 Alpha-E PF04168.7 EGO21392.1 - 0.057 12.7 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. RnfC_N PF13375.1 EGO21392.1 - 0.084 12.6 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 EGO21392.1 - 0.1 12.2 0.8 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like HSF_DNA-bind PF00447.12 EGO21393.1 - 7.8e-36 122.3 1.6 1.4e-35 121.5 1.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding GrpB PF04229.9 EGO21393.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 GrpB protein Ets PF00178.17 EGO21393.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Ets-domain CoaE PF01121.15 EGO21394.1 - 1.6e-63 213.3 0.0 1.9e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EGO21394.1 - 5.3e-07 29.9 0.1 2.2e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO21394.1 - 0.00023 21.9 0.2 0.00069 20.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EGO21394.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGO21394.1 - 0.018 14.9 0.0 0.94 9.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF3808 PF10300.4 EGO21395.1 - 2.6e-82 276.8 0.0 3.5e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 EGO21395.1 - 0.00021 21.5 6.6 0.23 11.8 0.0 4.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO21395.1 - 0.00042 19.9 2.6 0.046 13.3 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.1 EGO21395.1 - 0.00092 19.1 6.7 1.7 8.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO21395.1 - 0.0018 18.3 2.5 0.0052 16.9 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGO21395.1 - 0.033 14.8 3.3 0.73 10.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO21395.1 - 0.2 12.1 1.5 7.1 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO21395.1 - 0.32 11.0 12.3 1.5 8.8 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HEAT_2 PF13646.1 EGO21396.1 - 2.5e-16 59.7 9.6 0.019 15.2 0.0 7.7 3 2 2 6 6 6 5 HEAT repeats Arm PF00514.18 EGO21396.1 - 1.4e-14 53.2 9.6 0.002 17.9 0.1 9.5 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGO21396.1 - 2.3e-10 39.6 15.4 0.46 10.6 0.0 9.1 11 0 0 11 11 11 4 HEAT repeat Adaptin_N PF01602.15 EGO21396.1 - 1e-07 30.6 11.2 0.0019 16.6 2.7 5.0 2 1 1 4 4 4 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 EGO21396.1 - 3.8e-07 29.5 5.5 0.0011 18.1 0.3 3.5 1 1 2 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.2 EGO21396.1 - 0.00011 22.1 2.1 1 9.1 0.0 4.7 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EGO21396.1 - 0.00038 20.8 23.2 2.6 8.6 0.0 7.7 7 2 1 8 8 8 3 HEAT-like repeat CLASP_N PF12348.3 EGO21396.1 - 0.0013 18.1 0.1 0.15 11.3 0.0 3.1 2 1 1 3 3 3 1 CLASP N terminal DUF3361 PF11841.3 EGO21396.1 - 0.43 10.2 2.5 3.6 7.2 0.0 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3361) COG6 PF06419.6 EGO21397.1 - 4e-125 418.3 0.0 1.4e-124 416.5 0.0 1.8 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 H-kinase_dim PF02895.9 EGO21397.1 - 0.054 13.8 0.8 19 5.6 0.1 3.0 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain FAD_binding_3 PF01494.14 EGO21398.1 - 1.1e-82 277.9 0.0 7.6e-82 275.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO21398.1 - 1.6e-25 89.6 0.0 3.2e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EGO21398.1 - 0.00071 18.5 0.0 0.0013 17.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO21398.1 - 0.0013 18.6 0.3 0.0047 16.8 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO21398.1 - 0.0029 17.5 1.1 0.0086 16.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO21398.1 - 0.0033 16.3 0.3 0.0051 15.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO21398.1 - 0.0049 15.3 0.1 0.0092 14.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGO21398.1 - 0.0056 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EGO21398.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 EGO21398.1 - 0.02 13.8 0.1 0.034 13.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EGO21398.1 - 0.024 13.5 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGO21398.1 - 0.027 13.5 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EGO21398.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EGO21398.1 - 0.052 12.3 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 EGO21398.1 - 0.11 11.0 0.4 0.22 10.0 0.0 1.7 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 EGO21398.1 - 0.14 11.5 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_23 PF13489.1 EGO21401.1 - 2.6e-08 33.7 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NUC202 PF08166.7 EGO21401.1 - 0.032 14.0 1.5 0.076 12.8 0.1 2.2 2 0 0 2 2 2 0 NUC202 domain Methyltransf_11 PF08241.7 EGO21401.1 - 0.082 13.4 0.0 0.37 11.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGO21401.1 - 0.12 12.0 0.0 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.19 EGO21402.1 - 1.2e-92 310.8 18.0 2.2e-92 310.0 12.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO21402.1 - 1.8e-19 69.6 58.2 8.4e-18 64.2 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGO21402.1 - 0.00021 21.2 4.2 0.36 10.8 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF4238 PF14022.1 EGO21403.1 - 0.0055 16.0 1.4 0.0067 15.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF3678 PF12435.3 EGO21403.1 - 0.33 10.5 1.8 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) ESSS PF10183.4 EGO21405.1 - 2.7e-28 98.4 0.3 3.1e-28 98.2 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) E1_dh PF00676.15 EGO21406.1 - 6.1e-114 379.7 0.0 7.2e-114 379.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGO21406.1 - 0.00016 20.7 0.1 0.00028 19.8 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EGO21406.1 - 0.0031 17.0 2.4 0.0062 16.1 0.7 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Beta_elim_lyase PF01212.16 EGO21406.1 - 0.058 12.5 0.3 1.1 8.3 0.0 2.5 2 1 0 2 2 2 0 Beta-eliminating lyase Y_phosphatase3 PF13350.1 EGO21407.1 - 1.4e-35 122.9 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21407.1 - 1.2e-09 38.1 0.0 5.8e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGO21407.1 - 6.4e-05 22.3 0.0 0.00014 21.2 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO21407.1 - 0.0021 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGO21407.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO21407.1 - 0.089 12.8 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.9 EGO21407.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain F-box-like PF12937.2 EGO21410.1 - 2.3e-06 27.2 0.4 4.3e-05 23.1 0.3 2.4 1 1 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 EGO21411.1 - 1e-22 81.1 0.3 1.3e-22 80.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO21411.1 - 7.9e-10 38.6 0.0 2.1e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3 PF13350.1 EGO21412.1 - 4.1e-37 127.9 0.0 7.9e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO21412.1 - 4.3e-08 33.1 0.0 9.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGO21412.1 - 5.1e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO21412.1 - 0.00026 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGO21412.1 - 0.031 13.8 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EGO21412.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain STE3 PF02076.10 EGO21414.1 - 2.9e-73 246.4 13.7 3.3e-73 246.2 9.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor NYD-SP28_assoc PF14775.1 EGO21415.1 - 0.0064 16.1 1.5 0.011 15.3 1.1 1.3 1 0 0 1 1 1 1 Sperm tail C-terminal domain bZIP_1 PF00170.16 EGO21415.1 - 1.5 8.8 5.0 0.21 11.5 0.9 1.5 2 0 0 2 2 2 0 bZIP transcription factor TILa PF12714.2 EGO21417.1 - 3.5 7.4 7.7 5.3 6.8 0.4 2.4 2 0 0 2 2 2 0 TILa domain Response_reg PF00072.19 EGO21420.1 - 8.9e-23 80.4 0.1 1.9e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain TMPIT PF07851.8 EGO21421.1 - 0.54 9.2 2.8 0.82 8.6 1.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-RING_2 PF13639.1 EGO21422.1 - 1.9e-06 27.5 6.2 4.8e-06 26.3 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain PHD_2 PF13831.1 EGO21422.1 - 8.6e-05 21.7 2.4 0.00017 20.8 1.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EGO21422.1 - 0.00038 19.8 3.0 0.00074 18.8 2.1 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD PF00628.24 EGO21422.1 - 0.00044 19.8 6.5 0.0009 18.8 4.5 1.6 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 EGO21422.1 - 0.00079 19.3 6.2 0.0027 17.6 3.5 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain SWIM PF04434.12 EGO21422.1 - 0.00085 18.7 0.4 0.0016 17.8 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger C1_1 PF00130.17 EGO21422.1 - 0.0016 18.0 3.1 0.0016 18.0 2.2 2.0 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 EGO21422.1 - 0.0099 15.9 6.4 0.0099 15.9 4.5 1.8 2 0 0 2 2 1 1 RING-variant domain zf-rbx1 PF12678.2 EGO21422.1 - 0.014 15.4 4.5 0.014 15.4 3.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger ECM11 PF15463.1 EGO21422.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Extracellular mutant protein 11 zf-C3HC4_2 PF13923.1 EGO21422.1 - 0.093 12.7 9.7 0.033 14.2 4.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EGO21422.1 - 1.1 9.0 6.7 3 7.6 4.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EGO21422.1 - 4.1 7.2 12.6 0.92 9.2 5.3 2.5 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING-like PF08746.6 EGO21422.1 - 4.2 7.4 8.0 12 5.9 5.1 2.2 1 1 0 1 1 1 0 RING-like domain NAD_binding_10 PF13460.1 EGO21423.1 - 1.4e-08 34.9 0.0 9.3e-07 29.0 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO21423.1 - 0.00011 22.2 0.0 0.00022 21.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase DUF4552 PF15089.1 EGO21423.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Epimerase PF01370.16 EGO21423.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Coa1 PF08695.5 EGO21424.1 - 8.5e-28 96.2 0.0 1.1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.2 EGO21425.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.3 1 0 0 1 1 1 0 F-box-like LSM14 PF12701.2 EGO21426.1 - 2.8e-27 94.3 0.0 6.4e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EGO21426.1 - 4.2e-11 43.2 3.1 7.2e-11 42.5 2.2 1.4 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EGO21426.1 - 0.0075 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain SWI-SNF_Ssr4 PF08549.5 EGO21426.1 - 1 7.5 17.1 0.082 11.2 8.6 1.4 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) FANCF PF11107.3 EGO21427.1 - 0.074 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) CDC27 PF09507.5 EGO21427.1 - 7.8 5.6 18.1 0.92 8.6 9.1 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Glyoxal_oxid_N PF07250.6 EGO21430.1 - 7.5e-50 169.2 0.0 5.5e-49 166.4 0.0 2.2 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGO21430.1 - 1.5e-19 69.9 0.0 3.6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EGO21430.1 - 0.037 13.7 1.7 3 7.6 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Trp_DMAT PF11991.3 EGO21431.1 - 5.4e-84 282.4 0.0 1.1e-83 281.3 0.0 1.5 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Trp_DMAT PF11991.3 EGO21432.1 - 5.4e-84 282.4 0.0 1.1e-83 281.3 0.0 1.5 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase GST_N PF02798.15 EGO21434.1 - 6.7e-09 35.7 0.1 1.8e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21434.1 - 1.2e-05 25.1 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21434.1 - 0.0037 17.7 0.0 0.0086 16.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO21434.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO21435.1 - 4.6e-09 36.3 0.1 1.3e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21435.1 - 8.7e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21435.1 - 0.0025 18.2 0.0 0.0057 17.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO21435.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 EGO21436.1 - 2.9e-18 66.4 0.0 6.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO21436.1 - 1e-07 32.2 0.3 6.1e-05 23.1 0.3 2.7 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EGO21436.1 - 0.00044 19.5 0.5 0.15 11.2 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGO21436.1 - 0.0007 18.3 0.3 0.052 12.1 0.1 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGO21436.1 - 0.00073 19.0 0.9 0.0013 18.2 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO21436.1 - 0.003 17.5 0.1 0.0064 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EGO21436.1 - 0.0039 17.5 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EGO21436.1 - 0.0041 16.2 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EGO21436.1 - 0.005 16.3 0.3 0.063 12.7 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EGO21436.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGO21436.1 - 0.0069 17.2 0.0 0.017 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGO21436.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO21436.1 - 0.039 13.1 0.3 0.096 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGO21436.1 - 0.043 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO21436.1 - 0.072 13.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO21436.1 - 0.17 12.1 0.2 0.68 10.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EGO21436.1 - 0.21 11.1 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EGO21436.1 - 0.21 10.0 0.0 0.49 8.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain RVP_2 PF08284.6 EGO21441.1 - 0.041 13.8 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Imm_superinfect PF14373.1 EGO21441.1 - 0.057 13.0 0.2 0.08 12.5 0.2 1.2 1 0 0 1 1 1 0 Superinfection immunity protein WEMBL PF05701.6 EGO21442.1 - 0.0018 16.8 1.2 0.0021 16.6 0.8 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light mono-CXXC PF15626.1 EGO21442.1 - 0.61 10.0 3.3 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 single CXXC unit YABBY PF04690.8 EGO21442.1 - 1.1 9.5 3.9 1.3 9.2 2.7 1.1 1 0 0 1 1 1 0 YABBY protein Imm32 PF15579.1 EGO21447.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 1 1 0 1 1 1 0 Immunity protein 32 Transposase_21 PF02992.9 EGO21454.1 - 8.5e-13 47.9 0.1 1e-12 47.6 0.1 1.0 1 0 0 1 1 1 1 Transposase family tnp2 SNAPc19 PF15497.1 EGO21455.1 - 0.057 13.6 0.8 0.059 13.5 0.6 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Cys_rich_VLP PF14194.1 EGO21456.1 - 0.018 14.7 0.8 0.033 13.9 0.6 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP zf-RING_3 PF14369.1 EGO21456.1 - 0.15 12.0 4.3 0.26 11.3 1.8 2.1 1 1 1 2 2 2 0 zinc-finger Vfa1 PF08432.5 EGO21457.1 - 0.39 10.7 13.9 0.64 10.0 9.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4192 PF13830.1 EGO21457.1 - 0.67 9.5 3.5 0.45 10.0 1.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF755 PF05501.6 EGO21457.1 - 2.9 7.9 9.6 5.7 7.0 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Atrophin-1 PF03154.10 EGO21457.1 - 5.7 4.9 10.8 7.2 4.6 7.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family zf-CCHC PF00098.18 EGO21458.1 - 1.8e-08 33.8 4.4 3.3e-08 33.0 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO21458.1 - 3.6e-07 30.1 0.2 3.6e-07 30.1 0.1 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO21458.1 - 0.032 13.9 2.8 0.093 12.4 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle BMFP PF04380.8 EGO21458.1 - 0.094 12.8 1.0 6.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Membrane fusogenic activity Pkinase PF00069.20 EGO21459.1 - 2.1e-55 187.7 0.0 2.7e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21459.1 - 1.3e-35 122.7 0.0 2.7e-34 118.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO21459.1 - 0.0032 16.4 0.1 0.021 13.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EGO21459.1 - 0.045 12.5 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 TRM PF02005.11 EGO21460.1 - 9.6e-119 396.6 0.0 1.2e-118 396.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EGO21460.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EGO21460.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein NAD_binding_6 PF08030.7 EGO21461.1 - 6.3e-19 68.4 0.0 2.2e-16 60.1 0.0 2.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGO21461.1 - 2.9e-14 53.2 15.5 2.9e-14 53.2 10.8 2.7 2 1 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO21461.1 - 8.5e-13 48.0 0.0 3.9e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain HMA PF00403.21 EGO21462.1 - 2.5e-16 59.5 1.2 2.9e-16 59.3 0.8 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain AA_permease_2 PF13520.1 EGO21463.1 - 5.7e-65 219.5 39.1 7e-65 219.2 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO21463.1 - 3e-32 111.5 32.9 4.4e-32 111.0 22.8 1.2 1 0 0 1 1 1 1 Amino acid permease RNase_PH PF01138.16 EGO21464.1 - 1.2e-28 100.0 0.3 2e-28 99.3 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGO21464.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FA_synthesis PF02504.10 EGO21464.1 - 0.023 13.5 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein DUF2040 PF09745.4 EGO21465.1 - 6.4e-35 119.7 24.2 6.4e-35 119.7 16.8 3.4 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RRM_1 PF00076.17 EGO21466.1 - 2.9e-15 55.6 0.0 7.7e-15 54.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO21466.1 - 1.7e-12 47.0 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO21466.1 - 3.7e-08 33.0 0.0 1.6e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EGO21466.1 - 0.003 17.2 0.0 0.004 16.8 0.0 1.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EGO21466.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TFIID-18kDa PF02269.11 EGO21467.1 - 2.5e-20 72.0 0.0 3.6e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Mucin PF01456.12 EGO21467.1 - 4.3 7.0 18.9 7.5 6.3 13.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4211 PF13926.1 EGO21468.1 - 1.5e-32 112.1 0.4 8.4e-32 109.7 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4211) UNC-79 PF14776.1 EGO21469.1 - 2.4e-05 22.9 0.1 4.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 DPM2 PF07297.7 EGO21470.1 - 6.3e-25 87.2 0.9 7.2e-25 87.0 0.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EGO21470.1 - 1.2e-05 24.9 0.6 1.3e-05 24.8 0.4 1.1 1 0 0 1 1 1 1 PIG-P TRAPPC9-Trs120 PF08626.6 EGO21471.1 - 9.3e-126 420.7 0.0 8.9e-96 321.4 0.0 2.1 1 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Kinesin PF00225.18 EGO21472.1 - 2.4e-111 371.6 0.0 8.2e-111 369.9 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain Elf1 PF05129.8 EGO21473.1 - 3.5e-27 93.9 0.7 4.3e-27 93.6 0.5 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EGO21473.1 - 0.0013 18.8 0.3 0.0018 18.3 0.2 1.3 1 0 0 1 1 1 1 CHY zinc finger Cytochrom_c3_2 PF14537.1 EGO21473.1 - 0.048 14.0 0.5 0.072 13.4 0.4 1.3 1 0 0 1 1 1 0 Cytochrome c3 Nup96 PF12110.3 EGO21473.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Cytochrome_C554 PF13435.1 EGO21473.1 - 0.16 12.0 1.7 0.4 10.7 1.2 1.7 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Kinesin PF00225.18 EGO21474.1 - 1.1e-111 372.7 0.1 3.4e-111 371.1 0.1 1.9 1 0 0 1 1 1 1 Kinesin motor domain AAA_10 PF12846.2 EGO21474.1 - 2.5 7.4 12.3 1.9 7.8 0.0 2.7 2 1 1 3 3 3 0 AAA-like domain PUF PF00806.14 EGO21476.1 - 2.3e-70 228.2 1.5 3.3e-10 38.8 0.0 8.5 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Tenui_NCP PF04876.7 EGO21476.1 - 0.044 13.3 0.1 0.82 9.1 0.0 2.4 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein Sec16_C PF12931.2 EGO21477.1 - 9.7e-33 114.1 0.0 1.1e-32 113.8 0.0 1.0 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 OST3_OST6 PF04756.8 EGO21478.1 - 6.7e-15 55.0 1.5 1.1e-14 54.2 1.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EGO21478.1 - 0.004 16.8 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin 7TMR-DISM_7TM PF07695.6 EGO21478.1 - 0.54 9.9 6.6 1.3 8.6 4.6 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling Wzy_C PF04932.10 EGO21478.1 - 4.4 7.0 7.0 11 5.7 4.8 1.7 1 1 0 1 1 1 0 O-Antigen ligase Glyco_transf_15 PF01793.11 EGO21480.1 - 5.2e-141 469.3 3.1 6.4e-141 469.0 2.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EGO21481.1 - 5e-125 416.8 12.5 5.7e-125 416.6 8.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.17 EGO21482.1 - 9.4e-81 271.0 3.5 1.1e-80 270.8 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.22 EGO21483.1 - 1.1e-22 80.8 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO21483.1 - 2e-07 31.2 0.4 0.00061 19.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EGO21483.1 - 5.9e-05 22.4 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EGO21483.1 - 0.00011 21.8 0.0 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 EGO21483.1 - 0.00011 22.0 0.1 0.00087 19.1 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGO21483.1 - 0.00032 21.1 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO21483.1 - 0.00032 20.8 0.0 0.00054 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EGO21483.1 - 0.00046 19.8 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EGO21483.1 - 0.00049 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO21483.1 - 0.00063 19.7 0.0 0.0014 18.6 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EGO21483.1 - 0.00085 19.0 0.2 0.0036 16.9 0.1 1.9 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 EGO21483.1 - 0.0012 17.9 0.0 0.0076 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EGO21483.1 - 0.0045 16.5 0.0 0.01 15.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGO21483.1 - 0.0058 15.5 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EGO21483.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EGO21483.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGO21483.1 - 0.022 15.0 0.1 0.048 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO21483.1 - 0.024 15.4 0.7 0.04 14.7 0.5 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EGO21483.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.17 EGO21483.1 - 0.048 12.5 0.1 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EGO21483.1 - 0.054 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EGO21483.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGO21483.1 - 0.096 12.1 0.1 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGO21483.1 - 0.12 11.7 0.0 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EGO21483.1 - 0.15 10.6 0.4 4.6 5.6 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_13 PF13166.1 EGO21483.1 - 0.15 10.5 0.0 5.3 5.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF812 PF05667.6 EGO21486.1 - 0.0066 15.0 3.0 0.013 14.0 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF812) TSC22 PF01166.13 EGO21486.1 - 0.012 15.5 0.4 0.65 10.0 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Uso1_p115_head PF04869.9 EGO21486.1 - 0.065 11.9 0.2 0.068 11.9 0.2 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Seryl_tRNA_N PF02403.17 EGO21486.1 - 0.13 12.3 2.5 0.16 11.9 1.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EGO21486.1 - 0.16 11.5 3.4 0.19 11.2 2.4 1.2 1 0 0 1 1 1 0 IncA protein DUF3573 PF12097.3 EGO21486.1 - 0.23 10.0 2.0 0.24 9.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) K-box PF01486.12 EGO21486.1 - 0.28 10.9 1.9 1.1 9.0 0.1 2.0 2 0 0 2 2 2 0 K-box region bZIP_2 PF07716.10 EGO21486.1 - 0.34 10.7 2.2 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper NPV_P10 PF05531.7 EGO21486.1 - 0.78 10.0 7.3 9.1 6.6 5.0 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EGO21486.1 - 3 7.8 10.1 8.9 6.3 7.0 1.9 1 1 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 EGO21486.1 - 9.8 5.7 6.8 3.3 7.2 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF3552 PF12072.3 EGO21487.1 - 0.0026 17.0 2.0 0.015 14.5 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF4231 PF14015.1 EGO21487.1 - 0.095 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3357 PF11837.3 EGO21487.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PilS PF08805.6 EGO21488.1 - 0.02 14.4 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PilS N terminal DAGK_cat PF00781.19 EGO21489.1 - 4.3e-21 74.6 0.0 7e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Methyltransf_11 PF08241.7 EGO21490.1 - 1.2e-13 51.3 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO21490.1 - 3.7e-08 33.2 0.0 5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO21490.1 - 6.2e-07 29.9 0.0 1.7e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO21490.1 - 9.1e-07 29.2 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO21490.1 - 8.9e-06 25.7 0.1 1.6e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO21490.1 - 0.00038 20.0 0.0 0.0019 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO21490.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO21490.1 - 0.0017 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EGO21490.1 - 0.0018 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EGO21490.1 - 0.0087 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Rsm22 PF09243.5 EGO21490.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Unstab_antitox PF09720.5 EGO21490.1 - 0.091 12.4 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Putative addiction module component Methyltransf_24 PF13578.1 EGO21490.1 - 0.1 13.4 0.1 0.2 12.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGO21490.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MaoC_dehydratas PF01575.14 EGO21491.1 - 0.00055 19.3 0.1 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain Histone PF00125.19 EGO21492.1 - 1.3e-21 76.5 0.2 1.9e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO21492.1 - 5.4e-05 23.1 3.5 5.6e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGO21492.1 - 0.00026 21.1 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EGO21492.1 - 0.01 16.3 0.6 0.013 15.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EGO21492.1 - 0.064 12.7 0.1 0.095 12.1 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF3408 PF11888.3 EGO21492.1 - 0.23 11.3 2.7 0.38 10.6 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PRCC PF10253.4 EGO21493.1 - 1.1e-27 97.9 14.1 5e-27 95.7 9.8 2.3 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Nucleoporin_C PF03177.9 EGO21494.1 - 3.4e-58 197.5 6.5 4.7e-58 197.1 4.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGO21494.1 - 2.3e-21 76.0 0.0 3.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 EGO21496.1 - 2.6e-13 49.2 10.9 0.00042 20.0 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C2H2_jaz PF12171.3 EGO21497.1 - 8.2e-09 35.3 3.7 1.5e-08 34.4 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO21497.1 - 0.026 14.6 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGO21497.1 - 0.088 13.0 1.4 0.16 12.2 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Swi3 PF07962.7 EGO21498.1 - 4.2e-25 87.1 0.0 6.9e-25 86.4 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SR-25 PF10500.4 EGO21498.1 - 5.4 6.4 13.2 0.56 9.6 0.8 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Telomere_reg-2 PF10193.4 EGO21499.1 - 5.3e-23 81.4 0.0 1.1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein CobD_Cbib PF03186.8 EGO21499.1 - 0.018 14.1 0.0 0.88 8.5 0.0 2.2 2 0 0 2 2 2 0 CobD/Cbib protein adh_short PF00106.20 EGO21500.1 - 3.4e-14 53.0 0.4 8.3e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO21500.1 - 0.00052 19.7 0.0 0.0029 17.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Linker_histone PF00538.14 EGO21501.1 - 1.9e-16 59.9 0.0 5.9e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family AMP-binding PF00501.23 EGO21502.1 - 4e-20 71.5 0.0 5.7e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1161 PF06649.7 EGO21502.1 - 0.1 12.5 0.2 21 5.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1161) Tail_P2_I PF09684.5 EGO21502.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) WD40 PF00400.27 EGO21503.1 - 7.6e-11 41.4 16.1 6.9e-06 25.7 0.9 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat RXT2_N PF08595.6 EGO21503.1 - 0.11 12.2 0.5 0.35 10.6 0.4 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal 2Fe-2S_thioredx PF01257.14 EGO21504.1 - 7.9e-58 194.1 0.0 1e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.16 EGO21505.1 - 1.9e-48 164.8 0.1 6.2e-28 97.5 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel FixQ PF05545.6 EGO21505.1 - 0.12 11.9 0.2 0.65 9.6 0.2 2.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TEA PF01285.13 EGO21506.1 - 7.3e-22 78.1 1.8 3.1e-21 76.0 1.2 2.1 1 1 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EGO21506.1 - 0.024 14.6 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Peptidase_M1 PF01433.15 EGO21509.1 - 7.8e-98 328.0 6.8 4.8e-53 180.6 2.4 3.3 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EGO21509.1 - 5.1e-55 187.0 0.3 7.6e-55 186.4 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGO21509.1 - 3.6e-09 36.7 0.0 1.3e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 Peptidase MA superfamily DUF4115 PF13464.1 EGO21509.1 - 0.0082 15.7 0.0 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4115) DUF2808 PF10989.3 EGO21509.1 - 0.022 14.4 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) p450 PF00067.17 EGO21510.1 - 5.4e-76 255.9 0.0 4.3e-59 200.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EGO21511.1 - 4e-63 213.5 0.0 6.3e-63 212.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Pox_MCEL PF03291.11 EGO21512.1 - 1.4e-79 267.3 0.0 1.8e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 EGO21512.1 - 1.9e-09 37.4 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO21512.1 - 5.8e-07 30.0 0.0 9.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO21512.1 - 5.9e-07 29.8 0.0 9.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO21512.1 - 1.3e-06 28.6 0.0 2.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO21512.1 - 3.3e-06 27.4 0.0 7.6e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO21512.1 - 4.8e-06 26.2 0.0 7.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO21512.1 - 0.0001 21.7 0.0 0.0002 20.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EGO21512.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.12 EGO21512.1 - 0.0013 17.7 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 EGO21512.1 - 0.0022 18.0 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HECT PF00632.20 EGO21513.1 - 3.8e-88 295.6 0.0 5.2e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EGO21513.1 - 1.3e-33 114.4 21.5 1.5e-11 43.9 4.1 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EGO21513.1 - 1.8e-16 59.7 0.3 4.7e-16 58.3 0.2 1.8 1 0 0 1 1 1 1 C2 domain DUF4381 PF14316.1 EGO21514.1 - 0.047 13.8 0.2 0.051 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Hyd_WA PF06462.7 EGO21516.1 - 0.14 11.8 0.6 0.18 11.5 0.4 1.2 1 0 0 1 1 1 0 Propeller PaREP1 PF05942.6 EGO21518.1 - 0.00027 20.7 0.2 0.00027 20.7 0.2 2.4 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DUF2383 PF09537.5 EGO21518.1 - 0.0019 18.4 5.6 0.066 13.4 0.7 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) WD40_alt PF14077.1 EGO21518.1 - 0.31 10.7 2.2 0.74 9.4 1.5 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF972 PF06156.8 EGO21518.1 - 0.93 9.8 13.1 3.7 7.9 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 EGO21518.1 - 6.6 6.7 7.2 10 6.1 0.4 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) COQ7 PF03232.8 EGO21518.1 - 9 5.7 8.9 0.42 10.0 0.1 2.6 3 0 0 3 3 3 0 Ubiquinone biosynthesis protein COQ7 Mog1 PF04603.7 EGO21519.1 - 2.7e-36 124.5 0.3 3.5e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Spin-Ssty PF02513.12 EGO21519.1 - 0.15 11.6 0.7 0.39 10.2 0.1 1.9 2 0 0 2 2 2 0 Spin/Ssty Family RNase_T PF00929.19 EGO21521.1 - 1e-13 51.8 0.0 2.2e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Exonuclease CMS1 PF14617.1 EGO21522.1 - 6.5e-78 261.2 3.1 7.8e-78 261.0 2.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PEHE PF15275.1 EGO21522.1 - 0.013 15.9 0.4 0.026 14.9 0.3 1.5 1 0 0 1 1 1 0 PEHE domain ATP-synt_E PF05680.7 EGO21522.1 - 0.12 12.3 1.7 0.2 11.6 1.2 1.3 1 0 0 1 1 1 0 ATP synthase E chain PRP21_like_P PF12230.3 EGO21523.1 - 1.8e-56 191.2 15.3 1.8e-56 191.2 10.6 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGO21523.1 - 2.3e-34 116.8 0.6 6e-16 57.8 0.0 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 EGO21523.1 - 4.3e-07 29.2 0.0 8.9e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGO21523.1 - 0.0015 18.1 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO21523.1 - 0.036 14.2 0.5 0.25 11.5 0.0 2.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain PhoQ_Sensor PF08918.5 EGO21524.1 - 0.059 12.8 0.1 0.073 12.5 0.1 1.1 1 0 0 1 1 1 0 PhoQ Sensor UQ_con PF00179.21 EGO21525.1 - 2.9e-22 78.6 0.0 3.5e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGO21525.1 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 RWD domain Rubredoxin PF00301.15 EGO21525.1 - 0.036 13.9 0.0 0.036 13.9 0.0 2.5 4 0 0 4 4 4 0 Rubredoxin CHCH PF06747.8 EGO21526.1 - 4e-05 23.4 1.0 5.1e-05 23.0 0.7 1.2 1 0 0 1 1 1 1 CHCH domain DUF3128 PF11326.3 EGO21526.1 - 0.026 14.6 0.7 0.041 13.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) NYN PF01936.13 EGO21527.1 - 1.2e-07 32.1 0.0 1.3e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 NYN domain Transcrip_reg PF01709.15 EGO21528.1 - 1.3e-59 201.2 0.1 1.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pilus_CpaD PF09476.5 EGO21528.1 - 0.039 13.4 1.6 0.74 9.2 0.5 2.2 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Sulfate_transp PF00916.15 EGO21529.1 - 1e-76 257.6 7.0 1.8e-76 256.8 4.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGO21529.1 - 1.8e-31 107.6 4.3 1.8e-31 107.6 3.0 3.2 2 1 1 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGO21529.1 - 2.9e-10 39.5 0.0 5.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGO21529.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 EGO21530.1 - 3.5e-41 137.6 10.3 8.5e-12 44.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat adh_short_C2 PF13561.1 EGO21531.1 - 9.1e-25 87.8 0.0 1.5e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO21531.1 - 2.4e-24 86.1 0.2 3.2e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO21531.1 - 1.9e-11 43.9 0.1 2.9e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 KR domain UCR_14kD PF02271.11 EGO21532.1 - 7.6e-36 122.0 0.2 8.9e-36 121.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.16 EGO21533.1 - 2.8e-137 456.9 0.0 3.6e-137 456.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EGO21533.1 - 2.1e-42 144.6 0.0 2.1e-41 141.3 0.0 2.2 2 1 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGO21533.1 - 2e-13 50.3 0.0 4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EGO21533.1 - 0.00045 19.2 0.1 0.00091 18.2 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Cmc1 PF08583.5 EGO21534.1 - 1.1e-12 47.5 3.0 1.3e-12 47.2 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EGO21534.1 - 0.014 14.7 0.8 0.021 14.2 0.6 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 EGO21534.1 - 0.088 12.7 0.8 0.6 10.1 0.0 2.1 2 0 0 2 2 2 0 CHCH domain MFS_1 PF07690.11 EGO21535.1 - 6.8e-25 87.5 67.6 2.9e-14 52.5 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_63 PF03200.11 EGO21538.1 - 8.4e-233 774.7 0.1 6.3e-232 771.8 0.1 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EGO21538.1 - 3.5e-05 22.6 0.0 5.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase CUE PF02845.11 EGO21538.1 - 0.14 11.7 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 CUE domain Myosin_head PF00063.16 EGO21539.1 - 7.7e-223 741.4 0.0 1.5e-222 740.5 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EGO21539.1 - 1.1e-33 115.1 1.8 1.1e-33 115.1 1.2 2.2 2 0 0 2 2 1 1 DIL domain IQ PF00612.22 EGO21539.1 - 1.1e-13 49.4 33.9 0.0033 16.9 0.9 7.4 7 0 0 7 7 6 6 IQ calmodulin-binding motif SlyX PF04102.7 EGO21539.1 - 0.0021 18.3 15.9 0.0024 18.2 2.5 3.9 2 1 1 3 3 3 1 SlyX Lebercilin PF15619.1 EGO21539.1 - 0.0045 16.4 25.0 0.012 14.9 17.3 1.8 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 EGO21539.1 - 0.04 13.5 21.7 0.1 12.1 15.1 1.7 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EGO21539.1 - 0.071 13.2 10.5 0.14 12.3 6.2 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EGO21539.1 - 0.18 11.6 25.5 0.026 14.3 5.0 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EGO21539.1 - 0.27 10.3 9.6 0.99 8.5 1.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cep57_MT_bd PF06657.8 EGO21539.1 - 0.29 11.1 9.0 0.24 11.3 2.2 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 EGO21539.1 - 0.41 10.5 24.8 0.11 12.4 6.2 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EGO21539.1 - 0.5 8.7 17.7 0.94 7.8 12.3 1.3 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.2 EGO21539.1 - 0.69 9.1 29.0 1.3 8.3 7.9 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EGO21539.1 - 0.84 8.2 25.6 0.98 8.0 7.7 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 EGO21539.1 - 1.2 8.9 25.5 2 8.2 17.0 1.9 1 1 0 1 1 1 0 Tropomyosin like CCDC155 PF14662.1 EGO21539.1 - 2.2 7.8 27.3 32 4.0 18.7 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Atg14 PF10186.4 EGO21539.1 - 3.1 6.6 28.5 1.2 8.0 9.3 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EGO21539.1 - 5.8 7.2 10.4 16 5.8 0.5 3.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IFT57 PF10498.4 EGO21539.1 - 7.6 5.1 21.2 14 4.2 6.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3552 PF12072.3 EGO21539.1 - 7.6 5.6 26.4 0.33 10.1 7.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Retrotrans_gag PF03732.12 EGO21541.1 - 5.5e-07 29.5 0.1 5.5e-07 29.5 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EGO21542.1 - 0.00013 22.0 0.0 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO21542.1 - 0.0046 16.8 0.1 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 DUF3527 PF12043.3 EGO21544.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) CDC45 PF02724.9 EGO21546.1 - 0.071 11.1 13.5 0.094 10.7 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 EGO21546.1 - 0.13 11.7 13.0 0.2 11.0 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.8 EGO21546.1 - 0.21 11.1 18.1 0.36 10.4 12.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EGO21546.1 - 0.22 10.5 14.7 0.37 9.7 10.2 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO21546.1 - 1.2 6.9 16.9 0.75 7.6 10.0 1.7 2 0 0 2 2 2 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EGO21546.1 - 5.6 6.6 22.4 8.5 6.0 15.6 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AAA PF00004.24 EGO21547.1 - 2.7e-59 199.0 0.0 1.2e-43 148.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO21547.1 - 6.3e-07 30.2 0.0 0.0071 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO21547.1 - 1.5e-06 28.3 0.6 0.014 15.3 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EGO21547.1 - 2e-06 27.5 0.1 0.015 15.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO21547.1 - 4.9e-05 22.4 0.0 0.0045 16.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGO21547.1 - 0.00025 21.1 0.1 0.012 15.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EGO21547.1 - 0.00069 19.1 0.0 0.24 10.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EGO21547.1 - 0.00075 19.1 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGO21547.1 - 0.00098 19.4 0.0 0.12 12.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO21547.1 - 0.0014 18.0 0.1 0.0097 15.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EGO21547.1 - 0.0016 18.3 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGO21547.1 - 0.0025 16.5 0.0 0.022 13.5 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EGO21547.1 - 0.0033 17.1 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EGO21547.1 - 0.0039 17.0 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO21547.1 - 0.0049 17.0 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EGO21547.1 - 0.0059 16.0 1.1 0.044 13.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGO21547.1 - 0.0064 15.6 0.1 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EGO21547.1 - 0.016 15.1 0.0 0.07 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) SKI PF01202.17 EGO21547.1 - 0.02 14.7 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.1 EGO21547.1 - 0.025 14.1 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGO21547.1 - 0.03 13.9 0.4 3 7.4 0.1 2.6 3 0 0 3 3 2 0 NACHT domain PhoH PF02562.11 EGO21547.1 - 0.036 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EGO21547.1 - 0.037 13.6 0.3 0.093 12.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 EGO21547.1 - 0.038 14.0 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EGO21547.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGO21547.1 - 0.26 10.1 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF493 PF04359.9 EGO21548.1 - 0.088 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF493) RbsD_FucU PF05025.8 EGO21549.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 RbsD / FucU transport protein family Sel1 PF08238.7 EGO21554.1 - 4.4e-42 141.5 30.9 1e-07 32.3 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.1 EGO21554.1 - 0.0068 16.9 16.6 0.13 12.9 0.2 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO21554.1 - 0.045 14.2 0.4 4.2 8.0 0.1 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP_C PF03836.10 EGO21557.1 - 0.016 14.8 5.8 0.026 14.2 4.0 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Cu-oxidase_4 PF02578.10 EGO21557.1 - 0.18 10.8 1.8 0.27 10.2 1.3 1.2 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Cytochrom_NNT PF03264.9 EGO21557.1 - 1.7 8.0 4.9 2.4 7.5 3.4 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region HAUS6_N PF14661.1 EGO21557.1 - 3.3 6.9 9.8 4.2 6.6 6.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PGK PF00162.14 EGO21558.1 - 4.4e-146 486.3 0.0 5.1e-146 486.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF2857 PF11198.3 EGO21558.1 - 0.089 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) PrpR_N PF06506.6 EGO21558.1 - 0.12 11.7 0.2 0.38 10.1 0.1 1.8 1 0 0 1 1 1 0 Propionate catabolism activator Penaeidin PF05927.6 EGO21559.1 - 0.038 14.5 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 Penaeidin DUF3040 PF11239.3 EGO21559.1 - 0.14 12.2 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) gag_pre-integrs PF13976.1 EGO21561.1 - 2.6e-09 36.5 0.1 4.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 EGO21562.1 - 3.5e-06 26.5 0.1 6.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO21562.1 - 0.0003 20.5 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 EGO21562.1 - 0.032 13.8 2.3 0.061 12.9 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle JmjC PF02373.17 EGO21563.1 - 8.5e-09 35.6 0.5 3.1e-08 33.8 0.4 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EGO21563.1 - 1.1e-06 28.2 7.2 2.8e-06 26.9 5.0 1.8 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 EGO21563.1 - 0.00012 21.6 1.2 0.0003 20.3 0.2 2.2 2 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.1 EGO21563.1 - 0.14 11.5 5.2 0.3 10.4 3.6 1.6 1 0 0 1 1 1 0 PHD-finger DUF4206 PF13901.1 EGO21563.1 - 0.24 10.9 2.0 0.51 9.8 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) GFA PF04828.9 EGO21563.1 - 0.24 11.3 2.5 0.55 10.2 1.7 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme SRP72 PF08492.7 EGO21563.1 - 0.27 11.6 0.1 0.27 11.6 0.1 2.3 3 0 0 3 3 3 0 SRP72 RNA-binding domain Prok-RING_1 PF14446.1 EGO21563.1 - 1.1 9.0 5.0 0.76 9.5 2.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Retrotrans_gag PF03732.12 EGO21564.1 - 2e-05 24.5 2.6 2.9e-05 24.0 1.6 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein PepSY_TM_1 PF13172.1 EGO21565.1 - 5 6.9 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix Retrotrans_gag PF03732.12 EGO21566.1 - 6.8e-06 26.0 0.6 1.3e-05 25.1 0.4 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO21568.1 - 0.00059 19.6 2.3 0.00059 19.6 1.6 1.6 2 0 0 2 2 2 1 Zinc knuckle Toxin_44 PF15523.1 EGO21568.1 - 0.45 10.4 2.6 0.59 10.0 0.4 2.0 1 1 1 2 2 2 0 Putative toxin 44 Acetyltransf_13 PF13880.1 EGO21569.1 - 1e-13 50.7 0.0 2.3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EGO21569.1 - 5e-08 32.3 0.3 8.4e-08 31.6 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EGO21569.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO21569.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO21569.1 - 0.05 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glu_synthase PF01645.12 EGO21571.1 - 3.5e-158 526.3 0.0 5.2e-158 525.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EGO21571.1 - 1e-135 452.1 0.0 1.3e-135 451.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EGO21571.1 - 4e-116 387.2 0.0 6.2e-116 386.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EGO21571.1 - 9.5e-70 233.7 1.9 2.2e-69 232.5 1.3 1.6 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EGO21571.1 - 3.5e-23 81.3 0.1 7.9e-23 80.1 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EGO21571.1 - 2.3e-18 66.7 0.0 5.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO21571.1 - 8.4e-10 39.0 0.1 0.00024 21.2 0.1 2.7 2 1 1 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO21571.1 - 6.8e-08 32.4 0.0 2.9e-07 30.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO21571.1 - 1.7e-07 31.5 0.3 0.00017 21.9 0.1 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO21571.1 - 2.7e-06 26.5 0.2 0.00098 18.1 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO21571.1 - 1.9e-05 23.3 1.1 3.1e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EGO21571.1 - 4.2e-05 22.5 0.5 0.0035 16.2 0.0 2.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EGO21571.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EGO21571.1 - 0.0036 17.5 1.0 0.53 10.5 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FMN_dh PF01070.13 EGO21571.1 - 0.0064 15.3 1.8 0.021 13.7 0.5 2.2 3 0 0 3 3 3 1 FMN-dependent dehydrogenase FAD_binding_3 PF01494.14 EGO21571.1 - 0.017 14.2 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO21571.1 - 0.018 14.1 0.2 0.018 14.1 0.1 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EGO21571.1 - 0.025 14.1 0.2 0.2 11.1 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EGO21571.1 - 0.033 13.9 0.1 0.073 12.7 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 EGO21571.1 - 0.036 12.2 0.1 4.1 5.4 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.16 EGO21571.1 - 0.048 13.4 0.9 11 5.7 0.1 2.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.1 EGO21571.1 - 0.05 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.7 EGO21571.1 - 0.077 11.9 0.4 2.5 6.9 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGO21571.1 - 0.095 12.4 0.0 0.37 10.5 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EGO21571.1 - 0.16 11.3 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGO21571.1 - 0.18 11.4 0.1 0.46 10.1 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EGO21571.1 - 0.38 9.5 2.8 0.58 8.9 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.27 EGO21574.1 - 2e-47 157.4 15.9 1.9e-12 46.5 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO21574.1 - 1.1e-05 24.4 2.3 0.0072 15.1 0.1 3.5 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EGO21574.1 - 4.8e-05 21.7 1.7 0.36 8.9 0.1 3.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.6 EGO21574.1 - 8.4e-05 21.8 0.6 0.17 11.1 0.0 3.3 3 1 1 4 4 4 2 TUP1-like enhancer of split DUF3312 PF11768.3 EGO21574.1 - 0.084 11.0 0.0 0.13 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) CHORD PF04968.7 EGO21576.1 - 9.8e-41 137.8 10.3 2.7e-26 91.5 1.9 2.8 2 1 0 2 2 2 2 CHORD CS PF04969.11 EGO21576.1 - 2.4e-05 24.7 0.1 0.00034 21.0 0.1 2.3 1 1 0 1 1 1 1 CS domain GTP_EFTU PF00009.22 EGO21577.1 - 1.7e-39 135.2 2.0 1.2e-38 132.4 1.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGO21577.1 - 1.6e-26 92.3 1.2 1.6e-26 92.3 0.8 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EGO21577.1 - 4.3e-06 26.6 0.3 3.8e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGO21577.1 - 2e-05 24.1 0.8 0.0019 17.7 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.20 EGO21577.1 - 0.0001 22.3 4.7 0.0022 18.0 0.1 3.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Arf PF00025.16 EGO21577.1 - 0.0015 17.8 0.0 0.0045 16.2 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.1 EGO21577.1 - 0.0024 17.4 10.6 0.2 11.3 0.2 3.9 4 0 0 4 4 4 2 Elongation factor Tu domain 4 FeoB_N PF02421.13 EGO21577.1 - 0.0042 16.3 2.0 0.034 13.4 0.2 2.9 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EGO21577.1 - 0.0087 16.5 0.0 0.026 15.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein IF2_N PF04760.10 EGO21578.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Scramblase PF03803.10 EGO21579.1 - 6.1e-54 182.4 0.0 2e-53 180.7 0.0 1.7 1 1 0 1 1 1 1 Scramblase Chon_Sulph_att PF06566.6 EGO21579.1 - 0.012 15.2 0.1 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Chondroitin sulphate attachment domain CDC45 PF02724.9 EGO21580.1 - 3e-185 616.8 0.0 3.6e-185 616.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2201_N PF13203.1 EGO21580.1 - 0.12 11.4 7.0 0.12 11.4 1.4 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Spt5_N PF11942.3 EGO21580.1 - 1.9 9.1 14.0 0.055 14.0 4.8 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Lactamase_B PF00753.22 EGO21581.1 - 5.9e-24 84.7 2.4 7.7e-24 84.4 1.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO21581.1 - 0.007 15.9 0.1 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Herpes_gE PF02480.11 EGO21582.1 - 0.021 13.1 0.1 0.024 12.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_Coat_B PF05356.6 EGO21582.1 - 0.062 12.9 0.4 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Phage Coat protein B SSP160 PF06933.6 EGO21582.1 - 1.3 6.8 18.5 1.5 6.6 12.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGO21582.1 - 1.6 8.4 23.5 2.5 7.8 16.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FAM117 PF15388.1 EGO21582.1 - 1.7 7.7 14.9 2.3 7.3 10.3 1.1 1 0 0 1 1 1 0 Protein Family FAM117 SKG6 PF08693.5 EGO21582.1 - 5 6.5 7.3 0.19 11.0 0.7 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 EGO21582.1 - 7.9 6.8 14.7 1.6 9.1 6.9 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J SRP54 PF00448.17 EGO21583.1 - 1.9e-47 161.2 0.2 1.1e-46 158.7 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EGO21583.1 - 6.1e-44 150.4 0.1 7.1e-43 146.9 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EGO21583.1 - 8e-08 32.2 0.1 4.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EGO21583.1 - 1.4e-07 31.1 0.1 2.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGO21583.1 - 1.2e-05 24.2 0.0 2.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EGO21583.1 - 0.0024 17.4 0.0 0.0079 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGO21583.1 - 0.0037 16.9 0.0 0.0093 15.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EGO21583.1 - 0.0085 15.8 0.0 0.029 14.0 0.0 1.9 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 EGO21583.1 - 0.011 15.7 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ArsA_ATPase PF02374.10 EGO21583.1 - 0.014 14.4 0.4 1.2 8.0 0.0 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_22 PF13401.1 EGO21583.1 - 0.018 15.1 0.1 0.15 12.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Fer4_NifH PF00142.13 EGO21583.1 - 0.048 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Cyclin_N PF00134.18 EGO21584.1 - 1.1e-09 37.9 0.0 3.7e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain SPX PF03105.14 EGO21585.1 - 0.4 10.4 4.7 0.41 10.3 3.3 1.1 1 0 0 1 1 1 0 SPX domain THRAP3_BCLAF1 PF15440.1 EGO21585.1 - 8 4.9 28.3 9.2 4.7 19.6 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family SOG2 PF10428.4 EGO21585.1 - 9.7 4.7 11.5 11 4.5 7.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SOR_SNZ PF01680.12 EGO21586.1 - 3.4e-114 379.6 5.1 4.7e-114 379.1 3.5 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EGO21586.1 - 4.2e-09 35.8 3.0 1e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EGO21586.1 - 5.8e-05 22.0 0.1 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EGO21586.1 - 0.0015 17.8 0.5 0.22 10.7 0.0 3.0 2 1 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 EGO21586.1 - 0.0028 16.6 0.2 0.093 11.6 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EGO21586.1 - 0.003 16.7 4.9 0.014 14.5 0.1 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.16 EGO21586.1 - 0.0072 15.3 0.1 0.058 12.4 0.0 2.3 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 EGO21586.1 - 0.02 13.7 0.2 0.042 12.6 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF2984 PF11203.3 EGO21586.1 - 0.082 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Img2 PF05046.9 EGO21587.1 - 1.9e-16 60.0 0.0 2.4e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.12 EGO21589.1 - 1.4e-43 149.0 0.0 1.6e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Ras PF00071.17 EGO21590.1 - 2.1e-65 219.0 1.1 2.4e-65 218.8 0.8 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21590.1 - 3.4e-21 75.9 0.0 5.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO21590.1 - 2.5e-17 62.6 0.2 3e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO21590.1 - 4.8e-07 29.1 0.1 5.7e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGO21590.1 - 1.2e-06 28.1 0.2 2.5e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGO21590.1 - 1e-05 24.8 0.1 1.2e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO21590.1 - 2.7e-05 24.0 0.1 4.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGO21590.1 - 0.00089 19.4 0.0 0.0019 18.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EGO21590.1 - 0.0012 18.0 0.4 0.053 12.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EGO21590.1 - 0.0021 18.2 0.1 0.34 11.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EGO21590.1 - 0.0058 15.9 0.1 0.029 13.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EGO21590.1 - 0.014 15.3 0.2 0.042 13.8 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EGO21590.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EGO21590.1 - 0.036 13.5 0.7 0.083 12.4 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGO21590.1 - 0.037 13.9 0.2 0.19 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO21590.1 - 0.061 13.6 0.0 0.093 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 EGO21590.1 - 0.073 12.0 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EGO21590.1 - 0.096 12.1 0.1 1.1 8.7 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.18 EGO21591.1 - 4.9e-47 160.7 0.5 6.1e-47 160.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO21591.1 - 0.038 14.5 0.6 2.4 8.6 0.1 3.5 3 1 0 3 3 3 0 Aspartyl protease Zn_Tnp_IS1595 PF12760.2 EGO21592.1 - 0.023 14.5 2.1 0.085 12.6 1.4 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EGO21592.1 - 0.49 10.4 3.5 0.82 9.7 1.4 2.0 2 0 0 2 2 2 0 zinc-finger HAD_2 PF13419.1 EGO21593.1 - 4.8e-15 56.2 0.0 1.1e-11 45.2 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO21593.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EGO21593.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Nop16 PF09420.5 EGO21594.1 - 1e-31 110.2 2.6 3e-31 108.7 1.8 1.6 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zn_clus PF00172.13 EGO21595.1 - 0.015 15.2 0.8 0.032 14.1 0.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_1 PF00036.27 EGO21596.1 - 1e-24 83.8 0.6 2.5e-05 23.2 0.0 5.2 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO21596.1 - 1.2e-22 79.7 0.0 4.1e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO21596.1 - 3.1e-21 73.2 0.5 2.2e-05 23.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGO21596.1 - 5.1e-17 61.2 1.5 4.5e-06 26.1 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGO21596.1 - 4e-16 57.5 1.4 0.011 15.0 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_10 PF14788.1 EGO21596.1 - 0.034 13.8 0.1 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_2 PF09068.6 EGO21596.1 - 0.037 14.0 0.0 10 6.1 0.0 3.1 3 1 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 EGO21596.1 - 0.045 13.4 1.2 0.52 10.0 0.4 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand 2OG-FeII_Oxy_2 PF13532.1 EGO21597.1 - 4.3e-23 82.1 0.0 5.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA PF00627.26 EGO21598.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_M24 PF00557.19 EGO21599.1 - 3.4e-40 137.8 0.1 4.6e-40 137.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGO21599.1 - 0.0038 17.7 0.0 0.0072 16.8 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain MFS_1 PF07690.11 EGO21601.1 - 5.6e-30 104.2 24.7 5.6e-30 104.2 17.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EGO21602.1 - 6.3e-68 229.0 0.0 2.3e-67 227.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_cc PF11790.3 EGO21603.1 - 5.3e-61 206.0 1.4 6.3e-61 205.8 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.3 EGO21604.1 - 8e-69 231.6 1.3 9.2e-69 231.4 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1996 PF09362.5 EGO21605.1 - 2.1e-79 266.4 1.3 2.7e-79 266.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-Mss51 PF13824.1 EGO21606.1 - 1.4e-23 82.4 2.8 2.6e-23 81.6 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_M13_N PF05649.8 EGO21607.1 - 1.1e-92 311.0 0.0 1.4e-92 310.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EGO21607.1 - 2.4e-58 196.7 0.0 4.6e-58 195.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Piwi PF02171.12 EGO21608.1 - 4e-78 262.4 0.0 5.4e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGO21608.1 - 1.7e-10 40.0 0.0 4.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGO21608.1 - 0.0014 17.9 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DSPc PF00782.15 EGO21610.1 - 3.8e-19 68.5 0.2 5.1e-18 64.9 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO21610.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Sugar_tr PF00083.19 EGO21612.1 - 1.1e-101 340.6 23.8 1.3e-101 340.4 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO21612.1 - 1.3e-27 96.4 27.6 9.6e-27 93.6 14.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO21612.1 - 0.00034 18.9 3.3 0.00053 18.3 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1837 PF08878.6 EGO21612.1 - 0.079 12.5 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) PPR PF01535.15 EGO21612.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 PPR repeat PPR_1 PF12854.2 EGO21612.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 PPR repeat OATP PF03137.15 EGO21612.1 - 0.23 9.4 8.9 3.3 5.6 4.1 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PIG-P PF08510.7 EGO21612.1 - 0.75 9.4 0.0 0.75 9.4 0.0 2.6 3 0 0 3 3 3 0 PIG-P DUF2207 PF09972.4 EGO21612.1 - 0.93 7.9 5.1 0.088 11.3 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PRTase_2 PF15609.1 EGO21613.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase PPTA PF01239.17 EGO21614.1 - 1e-45 151.2 16.9 7e-10 37.8 0.0 6.3 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat Lzipper-MIP1 PF14389.1 EGO21614.1 - 0.056 13.5 0.3 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TPR_14 PF13428.1 EGO21615.1 - 3.1e-07 30.4 22.1 5.4 7.9 0.0 11.5 11 2 2 13 13 12 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO21615.1 - 6.8e-07 29.1 10.2 1.3 9.0 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO21615.1 - 4.3e-06 27.2 7.7 2.2 9.0 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO21615.1 - 1.5e-05 24.5 10.5 1.8 8.2 0.0 7.0 7 1 0 7 7 7 1 TPR repeat NRDE-2 PF08424.5 EGO21615.1 - 2.2e-05 23.4 7.2 0.1 11.4 0.1 4.6 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference Suf PF05843.9 EGO21615.1 - 0.00034 20.4 6.0 0.058 13.1 0.1 4.7 3 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGO21615.1 - 0.00054 20.2 6.1 5.8 7.3 0.1 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGO21615.1 - 0.011 15.5 7.2 1.7 8.4 0.2 5.6 5 2 2 7 7 7 0 Mad3/BUB1 homology region 1 FtsA PF14450.1 EGO21615.1 - 0.025 14.3 0.5 0.46 10.3 0.2 2.4 2 0 0 2 2 2 0 Cell division protein FtsA HAT PF02184.11 EGO21615.1 - 0.026 14.2 3.5 2.5 7.9 0.0 5.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat 4HB_MCP_1 PF12729.2 EGO21615.1 - 0.11 11.8 3.2 7.3 5.9 0.1 2.6 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction TPR_2 PF07719.12 EGO21615.1 - 0.65 10.0 25.7 2.3 8.3 0.1 7.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO21615.1 - 0.92 9.2 5.0 47 3.8 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 EGO21616.1 - 1.6e-24 84.8 7.6 4.4e-11 42.2 0.0 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF3445 PF11927.3 EGO21617.1 - 8e-49 166.2 0.0 9.7e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NMO PF03060.10 EGO21618.1 - 2.2e-73 247.2 1.4 2.7e-73 247.0 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO21618.1 - 5.8e-08 32.0 0.0 0.0085 15.0 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO21618.1 - 0.0016 17.3 2.5 0.0028 16.5 1.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyto_heme_lyase PF01265.12 EGO21619.1 - 4.4e-76 255.8 0.3 7.8e-75 251.8 0.2 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase APH PF01636.18 EGO21620.1 - 3.6e-07 30.1 0.2 5e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGO21620.1 - 0.00016 20.9 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EGO21620.1 - 0.00052 19.6 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGO21620.1 - 0.0094 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGO21620.1 - 0.038 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3678 PF12435.3 EGO21620.1 - 0.054 13.0 0.1 0.17 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Kinase-like PF14531.1 EGO21620.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EGO21621.1 - 1.1e-63 214.7 0.0 1.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21621.1 - 3.5e-29 101.6 0.0 4.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO21621.1 - 0.00016 20.7 0.0 0.00032 19.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGO21621.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MAT1 PF06391.8 EGO21622.1 - 1.3e-44 152.2 14.8 1.6e-44 151.9 10.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EGO21622.1 - 5.6e-06 25.9 7.4 1.5e-05 24.6 5.2 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO21622.1 - 3e-05 23.6 7.1 8.9e-05 22.0 5.1 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO21622.1 - 7e-05 22.4 5.7 0.00016 21.2 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO21622.1 - 0.00024 21.0 7.7 0.00085 19.3 5.6 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO21622.1 - 0.00041 20.1 8.2 0.0011 18.7 5.9 1.6 1 1 0 1 1 1 1 Ring finger domain DUF3887 PF13026.1 EGO21622.1 - 0.02 15.1 0.4 0.042 14.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) zf-RING_4 PF14570.1 EGO21622.1 - 0.023 14.2 3.1 0.23 11.0 0.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGO21622.1 - 0.039 14.0 2.0 0.071 13.2 1.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger YdjO PF14169.1 EGO21622.1 - 0.25 10.8 2.0 0.89 9.0 0.0 2.3 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.1 EGO21622.1 - 0.42 10.5 6.4 24 4.9 5.5 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO21622.1 - 0.96 9.2 4.9 1 9.1 1.5 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Proteasome PF00227.21 EGO21623.1 - 4.8e-59 198.8 0.0 6.7e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO21623.1 - 1.2e-14 53.2 0.1 1.2e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.8 EGO21624.1 - 4.1e-45 153.5 0.0 7.9e-45 152.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family C78 Sec7 PF01369.15 EGO21625.1 - 8.8e-61 204.8 0.1 1.5e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGO21625.1 - 2e-19 69.6 0.0 1.5e-09 37.5 0.0 3.1 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGO21625.1 - 0.0031 17.0 1.1 0.84 9.1 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Epimerase PF01370.16 EGO21626.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EGO21627.1 - 7.3e-39 133.2 0.3 9.8e-39 132.8 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGO21627.1 - 7.1e-30 103.5 0.0 1.5e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGO21627.1 - 0.0074 16.6 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DEAD PF00270.24 EGO21629.1 - 2.1e-19 69.6 0.0 3.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO21629.1 - 4.8e-13 48.7 0.1 1.4e-10 40.9 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EGO21629.1 - 3.3e-10 40.3 0.9 9e-10 38.9 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.10 EGO21629.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_6 PF12697.2 EGO21631.1 - 8e-22 78.2 0.0 1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO21631.1 - 3.9e-14 52.7 0.0 2.6e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO21631.1 - 7e-11 42.0 0.0 9.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGO21631.1 - 0.00072 19.3 0.0 0.01 15.5 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 EGO21631.1 - 0.00097 18.1 0.2 0.0047 15.8 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 EGO21631.1 - 0.039 13.5 0.0 0.7 9.4 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EGO21631.1 - 0.066 12.4 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family zf-AN1 PF01428.11 EGO21632.1 - 7.2e-16 57.7 18.6 2.7e-08 33.5 4.1 2.4 2 1 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EGO21632.1 - 3.8 7.4 16.4 0.05 13.4 2.8 2.5 1 1 1 2 2 2 0 IBR domain COG4 PF08318.7 EGO21633.1 - 3.8e-52 177.1 0.4 5.4e-52 176.6 0.2 1.2 1 0 0 1 1 1 1 COG4 transport protein Snf7 PF03357.16 EGO21634.1 - 3e-06 26.7 0.8 3.1e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 EGO21634.1 - 0.0059 16.6 0.4 0.0059 16.6 0.3 1.1 1 0 0 1 1 1 1 YlqD protein COG2 PF06148.6 EGO21634.1 - 0.012 15.5 0.3 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LZ_Tnp_IS481 PF13011.1 EGO21634.1 - 0.046 14.0 0.5 0.96 9.8 0.0 2.0 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 DUF2203 PF09969.4 EGO21634.1 - 0.059 13.5 0.2 0.062 13.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3186 PF11382.3 EGO21634.1 - 0.076 12.1 0.2 0.087 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) ATP-synt_B PF00430.13 EGO21634.1 - 0.08 12.7 2.2 0.1 12.4 1.5 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Sec20 PF03908.8 EGO21634.1 - 0.081 12.6 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Sec20 HTH_6 PF01418.12 EGO21634.1 - 0.14 11.9 1.0 0.37 10.5 0.4 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Pox_A_type_inc PF04508.7 EGO21634.1 - 0.55 10.1 3.1 1.2 9.1 2.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat 4F5 PF04419.9 EGO21634.1 - 5.8 7.7 7.5 1.1 10.0 2.8 1.6 2 0 0 2 2 1 0 4F5 protein family DUF1049 PF06305.6 EGO21634.1 - 7.7 6.0 7.0 6.8 6.2 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) zf-CCHC_3 PF13917.1 EGO21637.1 - 9.1e-07 28.5 1.9 1e-06 28.3 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO21637.1 - 1.8e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO21637.1 - 0.055 12.9 4.3 0.078 12.4 3.0 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PDGF PF00341.12 EGO21637.1 - 0.069 13.2 0.6 0.083 13.0 0.4 1.1 1 0 0 1 1 1 0 PDGF/VEGF domain Fungal_trans PF04082.13 EGO21638.1 - 2.1e-22 79.2 0.2 3.5e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO21638.1 - 1.5e-05 24.8 12.2 2.9e-05 23.8 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EGO21640.1 - 6.6e-07 28.9 3.2 2.7e-05 23.8 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 EGO21640.1 - 0.00057 18.1 0.2 0.001 17.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DnaJ PF00226.26 EGO21641.1 - 4.9e-23 80.6 1.0 8e-23 79.9 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO21641.1 - 1.4e-20 72.9 3.1 3.8e-18 65.1 0.0 3.2 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGO21641.1 - 2.4e-14 53.1 18.4 4.3e-14 52.3 12.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGO21641.1 - 0.13 11.9 10.3 0.39 10.4 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Peptidase_C21 PF05381.7 EGO21642.1 - 0.0092 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Tymovirus endopeptidase ADK PF00406.17 EGO21643.1 - 3.4e-44 150.3 0.1 5.9e-44 149.5 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGO21643.1 - 2.7e-07 30.9 0.1 5.7e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO21643.1 - 4.4e-06 27.5 0.0 8.1e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO21643.1 - 5.8e-05 22.9 0.0 0.00062 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGO21643.1 - 0.022 14.1 0.9 0.58 9.5 0.2 2.1 2 0 0 2 2 2 0 Thymidylate kinase DAGK_cat PF00781.19 EGO21644.1 - 5.9e-14 51.6 0.0 7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SDA1 PF05285.7 EGO21645.1 - 1.6e-75 254.3 32.0 4e-75 253.0 17.3 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EGO21645.1 - 7.2e-23 80.6 0.2 2.4e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 NUC130/3NT domain GalP_UDP_transf PF01087.17 EGO21646.1 - 2e-61 207.2 0.0 3.1e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EGO21646.1 - 1.6e-45 154.6 0.0 2.9e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EGO21646.1 - 0.0066 16.9 0.3 0.042 14.3 0.2 2.2 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO21646.1 - 0.15 12.3 2.7 0.42 10.8 1.0 2.3 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Glyco_hydro_3 PF00933.16 EGO21647.1 - 1.1e-75 254.4 0.0 1.7e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO21647.1 - 6.9e-68 228.5 0.0 5.3e-67 225.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO21647.1 - 4.1e-22 77.9 0.0 8.1e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EGO21647.1 - 1.8e-12 47.1 0.0 3.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF748 PF05359.6 EGO21647.1 - 0.0092 15.9 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 2 Domain of Unknown Function (DUF748) Pkinase_Tyr PF07714.12 EGO21648.1 - 4.2e-40 137.4 0.0 7.2e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO21648.1 - 6.2e-39 133.7 0.0 1.5e-38 132.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 EGO21648.1 - 0.005 15.8 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like ING PF12998.2 EGO21649.1 - 2e-10 40.8 0.1 5.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGO21649.1 - 2.3e-09 36.7 8.4 3.7e-09 36.1 5.8 1.3 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 EGO21649.1 - 0.072 13.0 1.2 0.13 12.2 0.9 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EGO21649.1 - 3.5 7.7 6.4 5.8 6.9 4.4 1.4 1 0 0 1 1 1 0 RING-like domain Nuf2 PF03800.9 EGO21650.1 - 7.8e-27 94.0 1.0 2.3e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family DUF972 PF06156.8 EGO21650.1 - 0.14 12.5 0.3 0.14 12.5 0.2 4.5 1 1 1 4 4 4 0 Protein of unknown function (DUF972) GAS PF13851.1 EGO21650.1 - 1.5 7.9 44.7 0.45 9.6 7.2 3.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DEAD PF00270.24 EGO21651.1 - 1e-21 77.1 0.0 3.4e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO21651.1 - 4.4e-18 64.9 0.0 1e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 EGO21651.1 - 1.3e-14 53.7 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 EGO21651.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO21652.1 - 3.2e-42 143.8 0.0 3.4e-41 140.5 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO21652.1 - 3.1e-23 81.4 0.0 8.4e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO21652.1 - 0.0014 18.4 0.1 0.43 10.3 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EGO21652.1 - 0.0031 17.4 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 EGO21652.1 - 0.0039 15.6 0.2 0.059 11.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EGO21652.1 - 0.23 10.4 7.0 2.7 6.9 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DDE_1 PF03184.14 EGO21653.1 - 1.1e-10 41.0 0.2 1.4e-10 40.7 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-HYPF PF07503.7 EGO21653.1 - 0.093 12.1 0.3 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 HypF finger Zn_clus PF00172.13 EGO21656.1 - 0.00038 20.3 16.6 0.00054 19.8 11.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EGO21656.1 - 5.6 5.0 12.4 5.9 4.9 8.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 His_Phos_2 PF00328.17 EGO21658.1 - 3.5e-45 154.8 0.0 1e-44 153.2 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 EGO21659.1 - 9.4e-56 188.8 0.0 1.2e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21659.1 - 1.1e-18 67.2 0.6 1.7e-18 66.6 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGO21659.1 - 0.00086 19.1 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO21659.1 - 0.013 14.8 0.2 0.047 13.0 0.1 1.9 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EGO21659.1 - 0.031 13.8 0.3 0.078 12.5 0.2 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.11 EGO21659.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 ABC1 family Transferase PF02458.10 EGO21661.1 - 3.9e-06 25.5 0.0 4.3e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family IPPT PF01715.12 EGO21662.1 - 3.1e-49 167.2 0.0 3.5e-25 88.4 0.0 2.9 2 1 0 2 2 2 2 IPP transferase AAA_18 PF13238.1 EGO21662.1 - 4e-06 27.1 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGO21662.1 - 7.2e-05 23.5 0.0 0.00015 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO21662.1 - 0.005 16.7 0.1 2.5 7.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGO21662.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGO21662.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EGO21662.1 - 0.063 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 EGO21662.1 - 0.071 13.2 0.1 0.41 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EGO21662.1 - 0.078 12.6 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B V-ATPase_H_C PF11698.3 EGO21664.1 - 0.087 12.7 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H PRP38 PF03371.10 EGO21665.1 - 8.4e-66 220.8 0.7 1e-65 220.5 0.5 1.1 1 0 0 1 1 1 1 PRP38 family DUF1777 PF08648.7 EGO21665.1 - 2.7 7.6 23.9 4.9 6.8 16.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Fasciclin PF02469.17 EGO21667.1 - 6e-26 90.9 0.0 2.4e-14 53.4 0.0 3.7 3 1 0 3 3 3 2 Fasciclin domain ATP-synt_ab PF00006.20 EGO21668.1 - 1.5e-113 377.6 0.0 2.1e-113 377.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO21668.1 - 8.9e-22 77.6 2.0 1.9e-21 76.6 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO21668.1 - 2.4e-15 56.4 3.4 6.7e-15 55.0 2.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain E2R135 PF11570.3 EGO21668.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 AAA_14 PF13173.1 EGO21668.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGO21669.1 - 3.4e-41 140.5 0.0 8.5e-41 139.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 EGO21669.1 - 4.5e-37 127.0 0.0 8.7e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGO21669.1 - 5.7e-14 51.7 0.0 5.4e-08 32.5 0.0 2.6 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EGO21669.1 - 2.4e-05 24.5 0.0 0.0012 19.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO21669.1 - 4.5e-05 23.2 0.0 0.00016 21.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO21669.1 - 7.4e-05 22.8 0.0 0.00091 19.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EGO21669.1 - 0.00074 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGO21669.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) HATPase_c_3 PF13589.1 EGO21669.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_17 PF13207.1 EGO21669.1 - 0.0036 18.0 0.1 0.013 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO21669.1 - 0.006 16.3 0.6 0.016 14.9 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EGO21669.1 - 0.0087 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EGO21669.1 - 0.013 15.4 0.0 0.05 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGO21669.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EGO21669.1 - 0.025 14.6 0.0 0.083 12.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EGO21669.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO21669.1 - 0.037 14.3 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO21669.1 - 0.05 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGO21669.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGO21669.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EGO21669.1 - 0.077 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 EGO21669.1 - 0.089 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EGO21669.1 - 0.089 11.9 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Phlebovirus_NSM PF07246.6 EGO21669.1 - 0.095 11.8 0.4 0.17 11.0 0.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_24 PF13479.1 EGO21669.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGO21669.1 - 0.14 11.6 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Mt_ATP-synt_D PF05873.7 EGO21669.1 - 0.15 11.6 1.2 0.44 10.1 0.8 1.9 2 0 0 2 2 1 0 ATP synthase D chain, mitochondrial (ATP5H) Arch_ATPase PF01637.13 EGO21669.1 - 0.22 11.1 1.5 12 5.5 0.0 2.6 2 1 1 3 3 2 0 Archaeal ATPase DUF4618 PF15397.1 EGO21669.1 - 0.25 10.6 1.7 0.6 9.3 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) AAA_23 PF13476.1 EGO21669.1 - 4.4 7.5 6.0 57 3.9 3.5 2.2 2 0 0 2 2 2 0 AAA domain PGM_PMM_I PF02878.11 EGO21670.1 - 5.4e-33 113.3 0.1 1.4e-32 112.0 0.0 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGO21670.1 - 2.6e-18 66.1 0.0 5.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGO21670.1 - 3.1e-14 53.1 0.0 6.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGO21670.1 - 3.2e-06 27.0 0.0 9.1e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MCM_bind PF09739.4 EGO21675.1 - 3.5e-22 78.2 0.0 6.9e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 EGO21675.1 - 1.4e-18 66.9 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Putative alanine racemase CDC50 PF03381.10 EGO21676.1 - 6.4e-85 284.6 0.0 1e-84 283.9 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RTC PF01137.16 EGO21677.1 - 8.1e-70 234.1 0.1 9.4e-70 233.9 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EGO21677.1 - 3.3e-20 72.0 0.8 6.2e-20 71.1 0.5 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TPR_MLP1_2 PF07926.7 EGO21678.1 - 0.00011 21.9 28.8 0.00016 21.3 6.3 4.4 4 0 0 4 4 4 2 TPR/MLP1/MLP2-like protein TSC22 PF01166.13 EGO21678.1 - 2.4 8.1 27.1 0.054 13.4 2.7 4.6 5 0 0 5 5 5 0 TSC-22/dip/bun family FUSC PF04632.7 EGO21678.1 - 4.2 5.6 10.0 0.97 7.7 4.3 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.1 EGO21678.1 - 6.5 5.6 16.1 2.5e+02 0.4 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HOOK PF05622.7 EGO21679.1 - 5.7e-26 90.5 17.4 6.1e-26 90.4 12.0 1.0 1 0 0 1 1 1 1 HOOK protein NYD-SP28_assoc PF14775.1 EGO21679.1 - 9.2e-05 22.0 2.6 9.2e-05 22.0 1.8 2.3 2 0 0 2 2 2 1 Sperm tail C-terminal domain bZIP_1 PF00170.16 EGO21679.1 - 0.00012 21.9 13.6 0.0017 18.2 1.9 4.0 3 1 1 4 4 4 1 bZIP transcription factor CCDC155 PF14662.1 EGO21679.1 - 0.00045 19.8 16.0 0.001 18.7 8.0 2.1 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 EGO21679.1 - 0.00061 19.5 22.7 0.075 12.8 0.4 4.0 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.5 EGO21679.1 - 0.0013 18.6 10.6 0.016 15.1 1.6 3.0 1 1 2 3 3 3 2 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.7 EGO21679.1 - 0.0018 17.9 16.7 0.029 14.1 8.5 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein IFT57 PF10498.4 EGO21679.1 - 0.0073 15.0 11.0 0.0096 14.6 7.6 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.2 EGO21679.1 - 0.0076 16.0 21.4 0.024 14.5 6.8 2.9 1 1 2 3 3 3 1 Tropomyosin like Pox_A_type_inc PF04508.7 EGO21679.1 - 0.0098 15.6 5.6 2.9 7.8 0.0 4.7 4 1 1 5 5 3 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.4 EGO21679.1 - 0.01 15.7 16.9 0.085 12.7 5.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.10 EGO21679.1 - 0.011 15.5 3.1 0.011 15.5 2.2 3.9 3 1 0 4 4 4 0 Basic region leucine zipper IMD PF08397.6 EGO21679.1 - 0.011 15.0 9.8 0.018 14.3 6.7 1.4 1 1 0 1 1 1 0 IRSp53/MIM homology domain Reo_sigmaC PF04582.7 EGO21679.1 - 0.012 14.8 1.4 0.39 9.8 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EGO21679.1 - 0.012 15.3 16.2 0.024 14.3 3.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cast PF10174.4 EGO21679.1 - 0.014 13.4 18.6 0.016 13.2 12.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone MscS_porin PF12795.2 EGO21679.1 - 0.014 14.6 13.1 0.12 11.6 5.0 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.7 EGO21679.1 - 0.015 15.0 11.1 0.07 12.8 3.3 2.5 1 1 2 3 3 3 0 Laminin Domain II GAS PF13851.1 EGO21679.1 - 0.019 14.1 17.7 0.051 12.7 12.3 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.5 EGO21679.1 - 0.019 15.1 12.9 0.99 9.6 2.7 3.4 1 1 2 3 3 3 0 Tup N-terminal BLOC1_2 PF10046.4 EGO21679.1 - 0.026 14.6 10.6 0.17 12.0 2.6 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 EGO21679.1 - 0.031 12.9 13.8 0.2 10.2 9.3 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Striatin PF08232.7 EGO21679.1 - 0.032 14.5 14.2 0.19 12.0 6.2 2.3 1 1 1 2 2 2 0 Striatin family DUF1192 PF06698.6 EGO21679.1 - 0.034 13.9 2.2 0.91 9.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Sec20 PF03908.8 EGO21679.1 - 0.052 13.2 5.0 0.36 10.5 0.3 2.9 1 1 2 3 3 3 0 Sec20 TBPIP PF07106.8 EGO21679.1 - 0.057 12.9 14.2 0.11 12.0 6.3 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin-6_N PF09177.6 EGO21679.1 - 0.067 13.6 6.1 0.78 10.1 2.1 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 EGO21679.1 - 0.068 12.7 14.8 1.2 8.7 10.3 2.1 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 EGO21679.1 - 0.07 11.5 11.0 0.2 10.1 6.1 1.4 1 1 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 EGO21679.1 - 0.1 12.8 6.8 3.1 8.1 0.1 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UBN2_2 PF14227.1 EGO21679.1 - 0.11 12.0 4.7 0.29 10.6 1.0 2.3 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type DPRP PF04244.8 EGO21679.1 - 0.11 12.0 3.4 0.13 11.7 2.1 1.4 1 1 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DUF2743 PF10899.3 EGO21679.1 - 0.11 11.8 1.8 0.12 11.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) KLRAQ PF10205.4 EGO21679.1 - 0.12 12.4 13.3 0.035 14.1 2.0 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.5 EGO21679.1 - 0.12 12.5 8.9 0.92 9.6 6.2 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.1 EGO21679.1 - 0.15 12.0 18.3 0.8 9.6 5.1 2.9 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 Phage_GP20 PF06810.6 EGO21679.1 - 0.17 11.3 17.6 1.7 8.0 8.8 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 Surfac_D-trimer PF09006.6 EGO21679.1 - 0.18 11.5 5.7 15 5.3 0.2 3.9 3 2 1 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DUF4298 PF14131.1 EGO21679.1 - 0.19 11.6 5.3 0.88 9.4 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) DUF3552 PF12072.3 EGO21679.1 - 0.19 10.8 18.8 1.2 8.2 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF972 PF06156.8 EGO21679.1 - 0.2 11.9 12.9 0.21 11.9 4.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FTA4 PF13093.1 EGO21679.1 - 0.21 11.0 11.7 0.66 9.3 7.6 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF904 PF06005.7 EGO21679.1 - 0.24 11.7 16.5 0.42 10.9 6.0 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF3618 PF12277.3 EGO21679.1 - 0.33 11.0 7.3 0.37 10.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) HAUS5 PF14817.1 EGO21679.1 - 0.33 9.4 10.1 1.2 7.6 2.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 ADIP PF11559.3 EGO21679.1 - 0.36 10.7 17.8 1.2 8.9 5.2 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EGO21679.1 - 0.42 9.5 15.4 0.66 8.9 10.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 FliD_N PF02465.13 EGO21679.1 - 0.44 10.9 6.7 7.4 7.0 2.8 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus zf-C4H2 PF10146.4 EGO21679.1 - 0.45 10.5 9.5 0.75 9.7 2.3 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein TSC22 PF01166.13 EGO21679.1 - 0.59 10.1 12.5 7.3 6.6 0.4 4.1 1 1 2 4 4 4 0 TSC-22/dip/bun family DUF4200 PF13863.1 EGO21679.1 - 0.67 9.9 17.1 2.2e+02 1.7 11.8 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Macoilin PF09726.4 EGO21679.1 - 0.97 7.6 16.3 1.1 7.4 11.3 1.0 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EGO21679.1 - 1.2 6.9 8.1 1.5 6.6 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 EGO21679.1 - 1.2 8.9 10.8 9.9 6.0 1.1 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 EGO21679.1 - 1.4 9.2 12.2 5.4 7.3 4.5 2.6 1 1 1 2 2 2 0 Spectrin repeat Viral_P18 PF04521.8 EGO21679.1 - 1.6 8.1 9.9 3.1 7.2 2.1 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Seryl_tRNA_N PF02403.17 EGO21679.1 - 1.8 8.6 18.2 0.99 9.4 6.1 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.8 EGO21679.1 - 2 7.4 8.9 1.5 7.8 5.0 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.9 EGO21679.1 - 2.1 7.9 12.8 7.5 6.1 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Toxin_39 PF15500.1 EGO21679.1 - 2.1 8.5 7.3 9.4 6.4 0.4 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin WXG100 PF06013.7 EGO21679.1 - 2.2 8.3 6.6 34 4.5 0.3 3.8 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF342 PF03961.8 EGO21679.1 - 2.4 6.4 10.5 1.5 7.1 5.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EGO21679.1 - 3.4 7.2 13.6 24 4.5 9.4 2.1 1 1 0 1 1 1 0 Mnd1 family Occludin_ELL PF07303.8 EGO21679.1 - 3.5 8.3 12.6 39 5.0 5.1 2.8 1 1 1 2 2 2 0 Occludin homology domain Exonuc_VII_L PF02601.10 EGO21679.1 - 3.9 6.5 10.2 4.9 6.2 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4446 PF14584.1 EGO21679.1 - 4 7.2 10.4 2.3 8.0 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DivIC PF04977.10 EGO21679.1 - 4.1 6.9 19.2 0.1 12.0 2.5 3.7 2 1 1 3 3 2 0 Septum formation initiator DUF1515 PF07439.6 EGO21679.1 - 4.6 7.1 6.6 3.9 7.3 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DivIVA PF05103.8 EGO21679.1 - 5.4 7.0 16.8 4.6 7.2 7.2 3.4 1 1 2 3 3 3 0 DivIVA protein Syntaxin PF00804.20 EGO21679.1 - 5.7 7.1 9.4 42 4.3 5.7 2.4 1 1 0 1 1 1 0 Syntaxin DUF4140 PF13600.1 EGO21679.1 - 7.1 7.1 15.1 5.6 7.4 0.9 3.6 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF106 PF01956.11 EGO21679.1 - 8.2 5.9 6.7 18 4.8 4.6 1.8 1 1 0 1 1 1 0 Integral membrane protein DUF106 UPF0449 PF15136.1 EGO21679.1 - 8.4 6.6 15.5 24 5.1 1.8 3.5 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 Phlebovirus_NSM PF07246.6 EGO21679.1 - 8.5 5.4 9.3 11 5.0 3.7 2.0 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF2203 PF09969.4 EGO21679.1 - 9.1 6.5 8.3 1.3e+02 2.7 5.7 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HOOK PF05622.7 EGO21680.1 - 0.0001 20.3 0.1 0.00011 20.2 0.1 1.0 1 0 0 1 1 1 1 HOOK protein DnaB_2 PF07261.6 EGO21680.1 - 0.041 13.4 0.1 0.044 13.3 0.0 1.0 1 0 0 1 1 1 0 Replication initiation and membrane attachment Sugar_tr PF00083.19 EGO21681.1 - 2.3e-76 257.1 9.4 2.9e-76 256.8 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO21681.1 - 1.6e-22 79.6 16.9 1.6e-22 79.6 11.7 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGO21681.1 - 6.4e-05 21.5 20.2 0.00057 18.3 2.4 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein Not1 PF04054.10 EGO21682.1 - 2.3e-118 395.3 1.2 1.4e-117 392.8 0.4 2.5 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGO21682.1 - 3e-51 172.9 0.9 7.7e-51 171.6 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Abhydrolase_5 PF12695.2 EGO21683.1 - 1.4e-13 50.8 0.1 2.9e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO21683.1 - 1.2e-08 35.1 2.8 2.5e-07 30.8 1.9 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO21683.1 - 1.8e-07 30.6 0.0 5.6e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGO21683.1 - 0.00053 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGO21683.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 EGO21683.1 - 0.015 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 EGO21683.1 - 0.019 14.4 0.0 1.9 7.8 0.0 2.8 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EGO21683.1 - 0.033 13.0 0.0 7.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DLH PF01738.13 EGO21683.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2920 PF11144.3 EGO21683.1 - 0.18 10.7 0.1 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) TMA7 PF09072.5 EGO21684.1 - 3.7e-21 75.3 22.3 4.1e-21 75.2 15.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 WD40 PF00400.27 EGO21685.1 - 3.7e-47 156.6 6.9 2.3e-10 39.9 0.0 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EGO21685.1 - 0.0043 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 EGO21685.1 - 0.0084 14.9 0.2 0.0084 14.9 0.1 3.7 3 2 0 3 3 3 1 Nup133 N terminal like PAT1 PF09770.4 EGO21685.1 - 0.91 7.6 25.0 1.2 7.3 17.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGO21685.1 - 1.3 7.1 30.1 1.7 6.7 20.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nucleo_P87 PF07267.6 EGO21685.1 - 1.6 7.3 11.2 2.3 6.8 7.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ndc1_Nup PF09531.5 EGO21685.1 - 2.8 6.2 7.0 5.1 5.3 4.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.2 EGO21685.1 - 3.3 5.2 9.0 4.1 4.9 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDFI PF15316.1 EGO21685.1 - 8.8 6.2 6.2 16 5.4 4.3 1.3 1 0 0 1 1 1 0 MyoD family inhibitor PDEase_II PF02112.10 EGO21686.1 - 1.1e-43 149.4 0.0 2e-43 148.5 0.0 1.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGO21686.1 - 6.1e-10 38.9 0.1 9.3e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO21686.1 - 0.07 12.7 0.4 0.15 11.6 0.3 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily EF-hand_4 PF12763.2 EGO21688.1 - 5.2e-36 122.5 0.0 1.4e-15 56.8 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EGO21688.1 - 3.3e-08 33.1 0.0 6.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 EGO21688.1 - 3.6e-08 33.4 0.1 0.00034 20.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair DUF869 PF05911.6 EGO21688.1 - 0.0003 19.1 9.8 0.00051 18.4 6.8 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) EF-hand_1 PF00036.27 EGO21688.1 - 0.0015 17.6 5.2 0.2 11.0 0.0 5.1 5 0 0 5 5 5 1 EF hand CENP-F_leu_zip PF10473.4 EGO21688.1 - 0.0064 16.3 9.1 0.0064 16.3 6.3 3.3 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_6 PF13405.1 EGO21688.1 - 0.049 13.5 8.8 23 5.2 0.0 5.8 6 0 0 6 6 6 0 EF-hand domain Fez1 PF06818.10 EGO21688.1 - 0.062 13.3 25.4 0.14 12.1 10.8 2.4 1 1 1 2 2 2 0 Fez1 EF-hand_8 PF13833.1 EGO21688.1 - 0.33 10.5 2.5 2.4 7.8 0.0 3.4 5 0 0 5 5 4 0 EF-hand domain pair Reo_sigmaC PF04582.7 EGO21688.1 - 0.92 8.6 8.8 1.2 8.3 0.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 EGO21688.1 - 2.4 7.2 24.0 0.51 9.4 3.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EGO21688.1 - 2.4 6.9 24.7 3.1 6.6 6.2 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Flagellin_C PF00700.16 EGO21688.1 - 3.9 7.6 12.0 0.39 10.9 0.8 3.1 2 1 1 3 3 2 0 Bacterial flagellin C-terminal helical region Tup_N PF08581.5 EGO21688.1 - 4 7.7 8.5 2.9 8.1 0.3 2.9 1 1 1 2 2 2 0 Tup N-terminal V_ATPase_I PF01496.14 EGO21688.1 - 4.1 5.1 7.1 6.2 4.5 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EGO21688.1 - 4.7 7.0 24.0 26 4.5 15.8 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.4 EGO21688.1 - 4.9 5.3 18.5 0.39 8.9 9.3 1.7 2 0 0 2 2 2 0 Transmembrane protein DUF4477 PF14780.1 EGO21688.1 - 6.1 6.1 5.3 18 4.6 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) UQ_con PF00179.21 EGO21689.1 - 7.6e-45 151.7 0.0 9.2e-45 151.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGO21689.1 - 0.00046 20.0 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGO21689.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B R3H PF01424.17 EGO21691.1 - 8e-12 44.6 0.1 1.8e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 EGO21691.1 - 1.4e-07 31.0 0.0 3.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO21691.1 - 2.8e-06 27.1 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO21691.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3824 PF12868.2 EGO21691.1 - 0.011 16.6 10.3 0.011 16.6 7.1 2.9 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) UvrD_C_2 PF13538.1 EGO21693.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Endonuclease_NS PF01223.18 EGO21695.1 - 2.5e-53 180.7 0.0 3e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease V-ATPase_H_N PF03224.9 EGO21696.1 - 3e-87 292.6 0.3 4.1e-87 292.2 0.2 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGO21696.1 - 1.9e-43 147.1 1.6 1.5e-42 144.2 0.1 2.5 3 0 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.17 EGO21696.1 - 0.00019 21.2 1.7 0.87 9.8 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EGO21696.1 - 0.001 19.2 0.3 0.75 10.1 0.1 3.1 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGO21696.1 - 0.032 14.7 0.2 11 6.6 0.0 4.1 3 1 1 4 4 4 0 HEAT-like repeat RNA12 PF10443.4 EGO21697.1 - 2.2e-115 385.6 0.0 6.1e-115 384.1 0.0 1.8 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 EGO21697.1 - 9.5e-06 25.7 0.8 3.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EGO21697.1 - 0.00045 19.9 0.0 0.0066 16.1 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EGO21697.1 - 0.0022 18.1 0.0 0.0061 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RRM_1 PF00076.17 EGO21697.1 - 0.0054 16.3 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zeta_toxin PF06414.7 EGO21697.1 - 0.032 13.3 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EGO21697.1 - 0.04 14.1 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGO21697.1 - 0.095 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AKNA PF12443.3 EGO21697.1 - 0.13 12.2 0.4 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor TPR_MLP1_2 PF07926.7 EGO21697.1 - 0.18 11.5 3.7 0.63 9.7 2.6 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_6 PF12774.2 EGO21697.1 - 0.19 11.2 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 Nucleoporin_FG PF13634.1 EGO21700.1 - 1.7 8.9 28.2 82 3.4 19.6 2.2 1 1 0 1 1 1 0 Nucleoporin FG repeat region Nucleoporin_FG PF13634.1 EGO21701.1 - 0.042 14.0 53.4 72 3.6 37.0 2.4 1 1 0 1 1 1 0 Nucleoporin FG repeat region Nup_retrotrp_bd PF10599.4 EGO21701.1 - 0.16 12.6 35.9 0.71 10.5 8.0 3.0 1 1 2 3 3 3 0 Retro-transposon transporting motif Tubulin PF00091.20 EGO21703.1 - 8.7e-73 244.6 0.0 1.6e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO21703.1 - 2.7e-47 159.9 0.1 5.4e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGO21703.1 - 0.00027 20.9 0.0 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGO21703.1 - 0.00044 19.7 0.0 0.00085 18.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain LGFP PF08310.6 EGO21703.1 - 0.079 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 LGFP repeat MBF1 PF08523.5 EGO21704.1 - 9.3e-22 76.8 1.9 9.3e-22 76.8 1.3 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EGO21704.1 - 4.9e-13 48.7 0.1 7.3e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EGO21704.1 - 7.9e-08 32.2 0.1 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EGO21704.1 - 0.0001 22.3 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 EGO21704.1 - 0.063 12.9 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain FAD-oxidase_C PF02913.14 EGO21705.1 - 8.4e-53 179.2 0.0 1.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO21705.1 - 1.1e-24 86.5 0.1 3.5e-24 84.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Imm39 PF15600.1 EGO21705.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 39 DUF3321 PF11968.3 EGO21706.1 - 4.6e-58 196.4 0.0 5.1e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EGO21706.1 - 1.7e-05 24.5 0.0 4.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Tetraspannin PF00335.15 EGO21707.1 - 4.6e-05 22.7 24.7 0.00014 21.2 17.1 2.1 1 1 0 1 1 1 1 Tetraspanin family TrbC PF04956.8 EGO21707.1 - 0.022 14.7 0.4 0.022 14.7 0.3 2.8 3 0 0 3 3 3 0 TrbC/VIRB2 family Na_Ca_ex PF01699.19 EGO21707.1 - 0.37 10.4 13.7 0.16 11.5 0.2 2.4 2 1 0 2 2 2 0 Sodium/calcium exchanger protein DUF3098 PF11297.3 EGO21707.1 - 0.37 10.5 4.0 3.1 7.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF4191 PF13829.1 EGO21707.1 - 0.47 9.5 11.8 0.61 9.1 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) PIRT PF15099.1 EGO21707.1 - 1.6 7.9 8.2 6.4 6.0 2.0 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family ResB PF05140.9 EGO21707.1 - 3.2 6.2 5.3 0.62 8.5 0.0 2.2 3 0 0 3 3 3 0 ResB-like family Baculo_11_kDa PF06143.6 EGO21707.1 - 4.8 6.6 8.4 1.6 8.1 0.1 2.7 2 1 0 2 2 2 0 Baculovirus 11 kDa family DUF872 PF05915.7 EGO21707.1 - 7.7 6.4 9.4 1.6 8.5 0.2 3.0 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) NAD_binding_7 PF13241.1 EGO21708.1 - 5.6e-29 100.4 0.0 1.4e-28 99.1 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGO21708.1 - 3.2e-18 64.8 0.3 5.5e-18 64.0 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGO21708.1 - 2.2e-16 58.5 0.7 3.6e-16 57.8 0.5 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 EGO21708.1 - 0.27 11.0 1.6 0.73 9.6 0.1 2.3 2 1 1 3 3 3 0 ThiF family 5_nucleotid_C PF02872.13 EGO21709.1 - 1.2e-24 87.0 0.0 2.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGO21709.1 - 2.5e-10 40.0 0.4 4.8e-10 39.1 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EGO21709.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Metallophos_2 PF12850.2 EGO21709.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF457 PF04307.9 EGO21710.1 - 0.082 12.2 2.3 0.11 11.7 1.5 1.4 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF2420 PF10336.4 EGO21711.1 - 3e-11 42.9 0.0 5.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Integrase_Zn PF02022.14 EGO21711.1 - 0.096 12.1 0.3 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain RNA_pol_Rpc82 PF05645.8 EGO21712.1 - 2.2e-17 63.4 8.5 6.8e-16 58.5 0.8 3.8 5 0 0 5 5 5 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EGO21712.1 - 4.5e-16 58.4 1.1 4.7e-12 45.5 0.2 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EGO21712.1 - 4.8e-10 38.8 0.2 2.6e-07 30.1 0.0 4.1 4 1 0 4 4 4 1 TFIIE alpha subunit Metallophos PF00149.23 EGO21713.1 - 0.083 12.2 0.3 0.18 11.1 0.2 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF572 PF04502.8 EGO21714.1 - 1.9e-88 296.8 6.7 2.3e-88 296.5 4.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) HrpA_pilin PF09589.5 EGO21714.1 - 0.014 15.7 0.3 0.063 13.7 0.1 2.0 2 0 0 2 2 2 0 HrpA pilus formation protein DUF866 PF05907.8 EGO21714.1 - 0.019 14.4 0.2 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 EGO21714.1 - 0.1 12.2 1.1 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Lar_restr_allev PF14354.1 EGO21714.1 - 0.1 12.9 0.7 8.7 6.7 1.3 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar eIF3_subunit PF08597.5 EGO21714.1 - 1.7 8.1 11.0 2.2 7.7 7.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SPT16 PF08644.6 EGO21715.1 - 6e-57 191.7 0.1 1.5e-56 190.4 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EGO21715.1 - 3.3e-29 101.5 0.1 4.3e-27 94.6 0.1 2.8 1 1 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EGO21715.1 - 3.1e-21 75.1 0.0 8.1e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EGO21715.1 - 2.9e-19 69.4 0.0 4.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Abhydrolase_6 PF12697.2 EGO21716.1 - 3e-26 92.7 0.1 3.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO21716.1 - 2.5e-17 63.2 0.0 4.9e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO21716.1 - 1.1e-12 47.9 0.0 1.9e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EGO21716.1 - 0.0033 16.3 0.2 0.013 14.3 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 EGO21716.1 - 0.0042 16.6 0.0 0.1 12.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 EGO21716.1 - 0.0075 15.5 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Hydrolase_4 PF12146.3 EGO21716.1 - 0.013 15.3 0.1 0.076 12.8 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase PGAP1 PF07819.8 EGO21716.1 - 0.043 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EGO21716.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.7 EGO21716.1 - 0.06 13.0 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GST_N_3 PF13417.1 EGO21717.1 - 3.9e-11 43.0 0.0 1.1e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO21717.1 - 1.1e-07 31.7 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21717.1 - 1.5e-05 24.9 0.0 4.5e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO21717.1 - 0.00057 19.7 0.2 0.002 18.0 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO21717.1 - 0.0013 18.8 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO21717.1 - 0.055 13.9 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PEGSRP PF07623.6 EGO21717.1 - 0.15 11.3 0.3 0.33 10.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) FMN_dh PF01070.13 EGO21718.1 - 1e-106 356.8 0.0 1.3e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGO21718.1 - 4.2e-20 71.3 0.0 7.7e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGO21718.1 - 0.00015 20.7 0.2 0.00032 19.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGO21718.1 - 0.00081 18.3 0.9 0.0043 15.9 0.3 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EGO21718.1 - 0.022 13.9 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase zf-C2HC PF01530.13 EGO21722.1 - 0.18 11.5 0.1 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 Zinc finger, C2HC type RepB-RCR_reg PF10723.4 EGO21724.1 - 2.4 7.9 7.6 2.6 7.8 5.2 1.1 1 0 0 1 1 1 0 Replication regulatory protein RepB DUF2296 PF10058.4 EGO21727.1 - 0.035 13.8 0.1 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Mis12 PF05859.7 EGO21730.1 - 1.6e-21 76.6 0.0 2.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein zf-DNL PF05180.7 EGO21730.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 DNL zinc finger Lactamase_B PF00753.22 EGO21731.1 - 0.0014 18.2 0.5 0.0026 17.4 0.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO21731.1 - 0.064 12.8 0.3 0.16 11.4 0.1 1.7 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Glyco_transf_4 PF13439.1 EGO21731.1 - 0.074 12.7 0.2 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DEAD PF00270.24 EGO21732.1 - 1.7e-43 148.0 0.4 3.5e-43 147.0 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO21732.1 - 6.2e-20 70.8 0.0 1.7e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO21732.1 - 1.5e-05 24.9 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO21732.1 - 0.0085 15.8 3.9 0.019 14.6 0.0 3.1 4 0 0 4 4 4 1 Part of AAA domain DUF2075 PF09848.4 EGO21732.1 - 0.019 13.9 0.0 0.047 12.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EGO21732.1 - 0.02 14.5 0.1 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Helicase EcoRII-C PF09019.6 EGO21732.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 EcoRII C terminal dsDNA_bind PF01984.15 EGO21733.1 - 1.8e-17 63.2 2.6 2e-17 63.1 1.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3774 PF12609.3 EGO21733.1 - 0.63 10.9 3.1 0.44 11.4 1.0 1.6 1 1 1 2 2 2 0 Wound-induced protein MUG113 PF13455.1 EGO21734.1 - 7.6e-15 55.1 0.0 4.2e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EGO21734.1 - 5.6e-11 42.7 0.0 8.3e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 T5orf172 domain AAA_32 PF13654.1 EGO21734.1 - 0.12 10.9 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3535 PF12054.3 EGO21736.1 - 9.8e-81 271.6 0.4 9.6e-80 268.3 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGO21736.1 - 1e-74 251.0 0.0 1.5e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UCH_1 PF13423.1 EGO21736.1 - 5.7e-49 167.1 0.0 1.7e-48 165.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EGO21736.1 - 2.4e-24 86.4 0.0 6.5e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 Exonuclease HEAT PF02985.17 EGO21736.1 - 1.9e-13 49.2 14.8 0.94 9.7 0.1 8.7 9 0 0 9 9 8 6 HEAT repeat Helicase_C PF00271.26 EGO21736.1 - 8.6e-12 44.7 0.0 2.3e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UCH PF00443.24 EGO21736.1 - 3.9e-09 36.0 0.0 8.2e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Vac14_Fab1_bd PF12755.2 EGO21736.1 - 0.0019 18.5 0.0 3.1 8.2 0.0 2.9 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGO21736.1 - 0.0057 17.1 16.9 14 6.3 0.0 8.1 7 2 3 10 10 8 0 HEAT-like repeat PQQ PF01011.16 EGO21736.1 - 0.029 13.9 0.0 1.8 8.2 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat LVIVD PF08309.6 EGO21736.1 - 0.045 12.7 0.3 0.095 11.7 0.2 1.6 1 0 0 1 1 1 0 LVIVD repeat CLASP_N PF12348.3 EGO21736.1 - 0.058 12.7 0.0 0.55 9.5 0.0 2.6 1 1 0 1 1 1 0 CLASP N terminal DUF1546 PF07571.8 EGO21736.1 - 0.12 12.5 0.2 5.9 7.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) WD40 PF00400.27 EGO21736.1 - 1.3 9.0 9.4 3.5 7.6 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Cupin_8 PF13621.1 EGO21737.1 - 2.1e-33 115.8 0.0 3.2e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGO21737.1 - 9.3e-07 28.3 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EGO21737.1 - 0.0012 19.0 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGO21737.1 - 0.0059 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain SOG2 PF10428.4 EGO21738.1 - 2.3e-45 155.1 1.6 2.3e-45 155.1 1.1 2.8 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EGO21738.1 - 7.3e-15 54.2 5.4 3.2e-06 26.6 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO21738.1 - 1.7e-13 50.0 7.2 1.7e-07 30.9 1.9 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EGO21738.1 - 1e-07 30.9 6.1 1.7 8.9 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EGO21738.1 - 0.00038 20.1 2.7 12 6.6 0.0 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EGO21738.1 - 0.0026 17.6 0.7 13 6.1 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat FYVE PF01363.16 EGO21739.1 - 4.5e-17 61.7 3.4 7.9e-17 60.9 2.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 EGO21739.1 - 0.002 17.6 0.3 0.0042 16.6 0.2 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.8 EGO21739.1 - 0.0092 15.7 5.4 0.0092 15.7 3.7 1.7 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type DUF4206 PF13901.1 EGO21739.1 - 0.02 14.4 1.1 0.06 12.8 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) FYVE_2 PF02318.11 EGO21739.1 - 0.024 14.5 1.1 0.024 14.5 0.8 2.2 1 1 0 2 2 2 0 FYVE-type zinc finger Toxin_65 PF15543.1 EGO21739.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative toxin 65 Cofilin_ADF PF00241.15 EGO21741.1 - 4.2e-23 81.5 0.0 4.4e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CoA_trans PF01144.18 EGO21742.1 - 7e-99 329.3 2.5 4.8e-58 195.8 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EGO21742.1 - 0.00018 21.2 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Cauli_VI PF01693.11 EGO21743.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Alpha_kinase PF02816.13 EGO21745.1 - 1.1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family CoA_trans PF01144.18 EGO21746.1 - 5.4e-104 346.0 4.5 3.8e-61 206.0 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EGO21746.1 - 0.00039 20.1 0.1 0.00075 19.2 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MmlI PF09448.5 EGO21746.1 - 0.08 12.6 0.1 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase AcetylCoA_hydro PF02550.10 EGO21746.1 - 0.13 12.0 0.1 2.1 8.0 0.0 2.7 4 0 0 4 4 4 0 Acetyl-CoA hydrolase/transferase N-terminal domain SMI1_KNR4 PF09346.5 EGO21747.1 - 5.4e-26 91.1 0.0 8.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Aldedh PF00171.17 EGO21748.1 - 1.8e-121 405.7 0.0 2.1e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO21748.1 - 0.0021 16.8 0.3 0.004 15.9 0.2 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cellulase PF00150.13 EGO21752.1 - 9.3e-10 38.1 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pectate_lyase_3 PF12708.2 EGO21753.1 - 1.4e-63 215.0 37.3 2.5e-41 142.2 5.6 4.3 3 1 0 3 3 3 3 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO21753.1 - 4.3e-08 32.5 1.6 8.4e-05 21.9 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Pkinase PF00069.20 EGO21757.1 - 9.1e-62 208.5 0.0 1.1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21757.1 - 3.9e-24 85.1 0.0 5.1e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO21757.1 - 1.7e-05 23.9 0.0 4.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO21757.1 - 0.0011 18.7 0.1 0.035 13.8 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO21757.1 - 0.0044 16.6 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.27 EGO21758.1 - 8.5e-63 206.1 19.5 2.3e-09 36.7 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGO21758.1 - 1.6e-11 43.7 0.4 3.6e-11 42.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO21758.1 - 3.4e-10 39.3 0.3 9.6e-10 37.8 0.2 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGO21758.1 - 1.1e-08 33.6 8.0 0.16 10.0 0.0 6.0 2 2 3 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGO21758.1 - 4.3e-05 23.2 0.0 4.5 7.0 0.0 5.0 3 2 3 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EGO21758.1 - 0.083 11.6 0.2 16 4.0 0.0 3.8 3 1 1 4 4 4 0 Nup133 N terminal like COQ7 PF03232.8 EGO21760.1 - 1.6e-64 216.5 0.4 1.9e-64 216.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.7 EGO21761.1 - 2.5e-05 24.0 0.1 2.6e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SH3_9 PF14604.1 EGO21761.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain G-patch PF01585.18 EGO21762.1 - 2.8e-14 52.6 2.3 6.6e-14 51.4 1.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGO21762.1 - 1.1e-06 28.4 1.5 3.5e-06 26.7 1.0 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-C2H2_jaz PF12171.3 EGO21762.1 - 0.004 17.2 0.7 0.0077 16.3 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.17 EGO21762.1 - 0.019 14.6 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.2 EGO21762.1 - 0.096 12.8 0.4 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RRM_5 PF13893.1 EGO21762.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 EGO21762.1 - 0.2 12.0 0.3 0.41 11.0 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO21762.1 - 0.24 11.8 0.8 0.5 10.8 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Lamp PF01299.12 EGO21762.1 - 1 8.4 5.9 0.16 11.1 0.5 2.0 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF4219 PF13961.1 EGO21764.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Exo5 PF09810.4 EGO21766.1 - 1.4e-56 192.1 0.0 3.7e-48 164.3 0.0 3.1 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EGO21766.1 - 0.049 13.0 0.2 1.5 8.0 0.0 2.7 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Metal_resist PF13801.1 EGO21766.1 - 0.081 12.9 0.3 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Heavy-metal resistance Ras PF00071.17 EGO21767.1 - 1.7e-53 180.3 0.0 2e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21767.1 - 9.4e-16 58.3 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO21767.1 - 6.8e-07 28.6 0.0 1.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO21767.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGO21767.1 - 0.03 13.7 0.1 0.64 9.4 0.0 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EGO21767.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EGO21767.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase rve PF00665.21 EGO21768.1 - 0.00025 21.1 0.0 0.00025 21.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain NACHT PF05729.7 EGO21769.1 - 0.0059 16.2 0.1 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Luteo_Vpg PF01659.11 EGO21770.1 - 0.0094 15.6 0.5 0.042 13.5 0.3 1.9 2 0 0 2 2 2 1 Luteovirus putative VPg genome linked protein Pyr_redox_2 PF07992.9 EGO21771.1 - 2.1e-37 128.9 0.3 4e-37 128.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGO21771.1 - 2.5e-32 111.1 0.5 5.1e-32 110.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGO21771.1 - 3.3e-21 75.4 4.2 8.6e-19 67.7 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO21771.1 - 1.7e-15 57.6 0.0 1.1e-09 38.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO21771.1 - 2.8e-08 33.0 0.0 4.2e-07 29.2 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EGO21771.1 - 5.1e-08 32.4 0.0 3.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO21771.1 - 1.2e-07 30.5 0.8 0.0042 15.6 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 EGO21771.1 - 0.00095 19.1 0.5 0.00095 19.1 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO21771.1 - 0.0011 17.9 3.2 0.38 9.5 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 EGO21771.1 - 0.0031 16.4 0.5 0.0031 16.4 0.4 2.9 3 1 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGO21771.1 - 0.02 14.6 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGO21771.1 - 0.025 13.6 0.1 0.063 12.3 0.0 1.7 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EGO21771.1 - 0.027 13.3 1.6 0.061 12.1 0.7 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EGO21771.1 - 0.059 13.0 0.9 0.4 10.3 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGO21771.1 - 0.26 10.9 1.2 0.63 9.7 0.0 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Asp_Glu_race PF01177.17 EGO21772.1 - 1.2e-24 87.4 0.0 1.4e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase LdpA_C PF12617.3 EGO21772.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal DUF1422 PF07226.6 EGO21773.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1422) Retrotrans_gag PF03732.12 EGO21775.1 - 1.7e-07 31.2 2.9 2.9e-07 30.4 0.1 2.7 1 1 1 2 2 2 1 Retrotransposon gag protein Hat1_N PF10394.4 EGO21779.1 - 3.6e-43 147.4 0.1 6.1e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.13 EGO21779.1 - 0.0023 17.1 0.2 0.0042 16.3 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.1 EGO21779.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO21779.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGO21779.1 - 0.067 13.3 0.1 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sterol-sensing PF12349.3 EGO21780.1 - 6e-37 126.4 5.5 8.8e-36 122.6 4.2 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGO21780.1 - 7.9e-17 60.4 1.1 1.1e-16 60.0 0.8 1.1 1 0 0 1 1 1 1 Patched family Biotin_lipoyl PF00364.17 EGO21781.1 - 1.2e-18 66.4 1.0 2.5e-18 65.4 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGO21781.1 - 2e-06 27.3 0.0 4.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGO21781.1 - 0.028 14.0 0.2 0.38 10.4 0.0 2.6 3 0 0 3 3 3 0 Biotin-lipoyl like QRPTase_N PF02749.11 EGO21781.1 - 0.15 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF4576 PF15144.1 EGO21781.1 - 3.6 7.2 6.3 1.5 8.5 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4576) Rad1 PF02144.11 EGO21782.1 - 3.9e-72 242.3 0.0 4.5e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PI-PLC-X PF00388.14 EGO21783.1 - 8.3e-07 28.5 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain tRNA-synt_1b PF00579.20 EGO21785.1 - 7.7e-22 77.7 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TBP PF00352.16 EGO21786.1 - 1.6e-68 226.0 0.2 3.7e-34 115.9 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGO21786.1 - 0.00057 19.8 0.7 1 9.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) Glyco_hydro_88 PF07470.8 EGO21788.1 - 8e-18 64.5 0.2 9.7e-18 64.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EGO21788.1 - 0.0037 16.5 0.5 0.073 12.3 0.0 2.2 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus PQQ PF01011.16 EGO21788.1 - 0.073 12.6 0.5 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat Dynamin_M PF01031.15 EGO21789.1 - 1.1e-104 349.3 0.0 1.7e-104 348.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGO21789.1 - 6.7e-55 185.4 0.0 1.4e-54 184.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGO21789.1 - 1.4e-28 98.6 2.7 3.3e-28 97.4 1.9 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO21789.1 - 0.00089 19.1 0.6 0.028 14.3 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGO21789.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NTF2 PF02136.15 EGO21790.1 - 2.3e-30 105.4 0.0 2.5e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3549 PF12069.3 EGO21790.1 - 0.015 14.0 0.0 0.039 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3549) T4_baseplate PF12322.3 EGO21790.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-C3HC4_3 PF13920.1 EGO21792.1 - 1.8e-05 24.3 10.1 0.0032 17.0 4.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO21792.1 - 2.3e-05 24.0 13.8 0.00034 20.2 6.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO21792.1 - 0.00018 21.2 14.2 0.0037 17.0 7.3 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGO21792.1 - 0.02 14.5 12.5 0.022 14.4 5.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO21792.1 - 0.023 14.5 11.6 0.039 13.8 5.5 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO21792.1 - 0.025 14.2 2.6 0.025 14.2 1.8 3.6 4 0 0 4 4 3 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGO21792.1 - 0.036 14.0 14.5 0.04 13.9 7.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EGO21792.1 - 0.037 13.5 1.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 SAP domain zf-RING_6 PF14835.1 EGO21792.1 - 0.045 13.5 5.2 0.029 14.1 1.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TerY-C PF15616.1 EGO21792.1 - 0.22 11.4 9.1 1.4 8.8 2.0 2.8 3 0 0 3 3 3 0 TerY-C metal binding domain zf-RING_4 PF14570.1 EGO21792.1 - 1.1 8.8 10.9 1.8 8.2 2.8 2.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain HypA PF01155.14 EGO21792.1 - 1.2 8.7 6.0 8 6.1 2.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF329 PF03884.9 EGO21792.1 - 1.3 8.6 11.2 0.62 9.6 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-Di19 PF05605.7 EGO21792.1 - 5.9 7.0 11.3 3.8 7.7 0.1 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF59 PF01883.14 EGO21795.1 - 4e-12 45.9 0.1 9e-12 44.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 DUF371 PF04027.8 EGO21795.1 - 0.081 12.5 0.1 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF371) Wzz PF02706.10 EGO21795.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Chain length determinant protein MIF PF01187.13 EGO21798.1 - 1.3e-13 50.9 0.0 1.5e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.13 EGO21799.1 - 6.6e-13 48.7 0.0 7.5e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.13 EGO21802.1 - 1.8e-12 47.3 0.0 2e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_4 PF13147.1 EGO21803.1 - 1.1e-15 58.3 1.5 4.9e-15 56.3 1.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGO21803.1 - 5.9e-13 49.1 0.1 8.4e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO21803.1 - 7.1e-13 48.1 0.1 2.4e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO21803.1 - 4.6e-07 29.3 0.1 0.011 14.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.7 EGO21803.1 - 0.018 14.6 0.3 5.1 6.8 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Methyltransf_PK PF05891.7 EGO21804.1 - 3.4e-55 186.7 0.1 5.4e-53 179.5 0.0 2.8 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 EGO21804.1 - 3.7e-05 24.1 0.2 0.0067 16.8 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO21804.1 - 5.7e-05 23.6 0.0 0.00012 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO21804.1 - 0.00029 21.1 0.0 0.0007 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO21804.1 - 0.00069 20.0 0.0 0.0025 18.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO21804.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGO21804.1 - 0.0057 15.8 0.6 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Rpp20 PF12328.3 EGO21805.1 - 0.00048 19.7 6.9 0.0028 17.3 0.1 3.7 2 1 2 4 4 4 1 Rpp20 subunit of nuclear RNase MRP and P eRF1_2 PF03464.10 EGO21806.1 - 3.9e-45 153.4 0.1 8.1e-45 152.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGO21806.1 - 1.2e-37 128.5 0.3 2.5e-37 127.6 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGO21806.1 - 1.6e-26 92.4 0.0 3.3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 BAALC_N PF06989.7 EGO21807.1 - 0.34 11.2 0.3 0.34 11.2 0.2 2.2 2 0 0 2 2 2 0 BAALC N-terminus Phosducin PF02114.11 EGO21808.1 - 3.7e-07 29.1 0.0 6.8e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Phosducin Ribonuclease_3 PF00636.21 EGO21809.1 - 4.3e-39 133.5 0.0 1.4e-18 67.3 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGO21809.1 - 8.1e-28 96.9 1.9 3.2e-15 56.2 0.0 4.3 3 2 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EGO21809.1 - 4.5e-15 55.5 0.0 9.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO21809.1 - 8.1e-14 51.8 0.1 1.7e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO21809.1 - 8.2e-13 48.0 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EGO21809.1 - 9.3e-10 38.1 0.0 3.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain SNF2_N PF00176.18 EGO21809.1 - 4.4e-07 28.9 0.0 7.8e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ras PF00071.17 EGO21810.1 - 6.5e-54 181.6 0.0 7.4e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21810.1 - 9.1e-16 58.4 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO21810.1 - 7.3e-07 28.5 0.0 9.9e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.17 EGO21811.1 - 1.4e-33 114.3 0.0 6.9e-18 64.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO21811.1 - 3e-15 55.9 0.0 2.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO21811.1 - 2.6e-08 33.6 0.0 0.00074 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1077 PF06417.7 EGO21812.1 - 3.1e-46 155.8 0.1 4.1e-46 155.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TraE PF05309.6 EGO21813.1 - 0.071 12.2 0.8 0.097 11.8 0.5 1.2 1 0 0 1 1 1 0 TraE protein DUF4029 PF13221.1 EGO21813.1 - 0.23 11.8 8.1 0.3 11.4 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) PIG-X PF08320.7 EGO21814.1 - 4.2e-25 88.2 0.1 9.6e-25 87.0 0.1 1.4 1 1 0 1 1 1 1 PIG-X / PBN1 ADK PF00406.17 EGO21815.1 - 4.8e-60 201.8 0.0 6.3e-60 201.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGO21815.1 - 3.5e-14 52.1 0.0 6.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EGO21815.1 - 0.00014 21.7 0.0 0.00043 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO21815.1 - 0.00016 22.4 0.0 0.00026 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO21815.1 - 0.0043 16.1 0.0 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Arena_nucleocap PF00843.12 EGO21815.1 - 0.049 11.5 0.1 0.093 10.6 0.0 1.3 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein AAA_18 PF13238.1 EGO21815.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.12 EGO21815.1 - 0.13 12.3 0.1 0.71 9.9 0.0 2.2 2 1 0 2 2 2 0 Retrotransposon gag protein Beta-lactamase PF00144.19 EGO21816.1 - 3e-28 98.8 0.1 4.2e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DDOST_48kD PF03345.9 EGO21818.1 - 1.5e-100 336.7 0.0 1.8e-100 336.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta APG6 PF04111.7 EGO21819.1 - 0.83 8.6 5.4 1.2 8.1 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Asp PF00026.18 EGO21821.1 - 2.6e-27 95.8 0.2 2.9e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGO21821.1 - 2.6e-06 27.0 0.1 3.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal V_ATPase_I PF01496.14 EGO21822.1 - 6.7e-274 910.4 0.0 8.3e-274 910.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Clusterin PF01093.12 EGO21822.1 - 0.26 10.0 0.4 0.41 9.3 0.3 1.2 1 0 0 1 1 1 0 Clusterin SlyX PF04102.7 EGO21822.1 - 0.55 10.6 2.2 1.2 9.5 0.2 2.4 3 0 0 3 3 3 0 SlyX ABC_tran PF00005.22 EGO21823.1 - 1.2e-42 145.4 0.0 2.2e-20 73.3 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO21823.1 - 8.6e-14 52.1 6.5 4.5e-05 23.5 0.6 4.5 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EGO21823.1 - 2.7e-12 46.4 0.9 0.0047 16.1 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGO21823.1 - 1.3e-08 34.2 0.2 0.007 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO21823.1 - 1.1e-07 32.7 0.1 0.00065 20.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGO21823.1 - 3.4e-06 27.5 0.0 0.094 13.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 EGO21823.1 - 7.5e-06 25.7 0.0 0.03 14.2 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EGO21823.1 - 8.4e-06 25.7 0.0 0.0039 17.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EGO21823.1 - 1.1e-05 25.5 0.0 0.059 13.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EGO21823.1 - 1.4e-05 24.6 0.2 0.037 13.4 0.0 2.8 3 0 0 3 3 2 2 AAA-like domain NACHT PF05729.7 EGO21823.1 - 2.2e-05 24.2 0.1 0.26 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EGO21823.1 - 4e-05 23.9 0.2 0.045 14.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain Chromo PF00385.19 EGO21823.1 - 4.3e-05 23.0 0.2 9.5e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MobB PF03205.9 EGO21823.1 - 4.8e-05 23.0 0.1 0.38 10.4 0.0 3.5 4 0 0 4 4 3 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGO21823.1 - 5.1e-05 23.2 0.4 0.16 11.8 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EGO21823.1 - 5.2e-05 23.4 0.0 2.1 8.5 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGO21823.1 - 5.6e-05 22.3 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGO21823.1 - 8.2e-05 22.0 0.8 0.28 10.5 0.0 4.0 4 1 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EGO21823.1 - 8.6e-05 22.6 0.1 0.38 10.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase HEAT PF02985.17 EGO21823.1 - 9.4e-05 22.1 0.9 3.8 7.8 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat AAA_33 PF13671.1 EGO21823.1 - 0.00026 20.8 0.0 0.64 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGO21823.1 - 0.00026 19.8 0.4 0.35 9.6 0.1 2.5 2 0 0 2 2 2 2 ArgK protein HEAT_2 PF13646.1 EGO21823.1 - 0.00037 20.7 9.7 0.02 15.1 0.1 3.7 2 1 2 4 4 3 2 HEAT repeats AAA_16 PF13191.1 EGO21823.1 - 0.00045 20.2 6.1 0.012 15.6 0.3 4.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EGO21823.1 - 0.00058 19.8 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGO21823.1 - 0.0006 20.2 8.9 0.037 14.3 0.0 3.3 4 0 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 EGO21823.1 - 0.00066 19.4 0.1 3.7 7.1 0.0 3.7 3 0 0 3 3 3 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EGO21823.1 - 0.0032 16.9 0.2 0.8 9.1 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_15 PF13175.1 EGO21823.1 - 0.0056 15.7 0.2 5.6 5.8 0.0 3.3 2 1 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.8 EGO21823.1 - 0.0056 15.6 0.1 2.2 7.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EGO21823.1 - 0.0062 16.0 0.0 2.3 7.6 0.0 4.0 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EGO21823.1 - 0.012 15.4 0.0 0.53 10.0 0.0 2.8 2 0 0 2 2 2 0 Dynamin family HEAT_EZ PF13513.1 EGO21823.1 - 0.012 16.0 7.8 2 9.0 0.1 5.5 4 2 2 6 6 5 0 HEAT-like repeat AAA_14 PF13173.1 EGO21823.1 - 0.019 14.8 0.1 4 7.3 0.1 3.2 2 1 0 2 2 2 0 AAA domain U3snoRNP10 PF12397.3 EGO21823.1 - 0.047 13.6 0.8 0.15 12.0 0.6 1.9 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 T2SE PF00437.15 EGO21823.1 - 0.048 12.5 0.1 0.42 9.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_13 PF13166.1 EGO21823.1 - 0.057 11.8 3.1 2.4 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EGO21823.1 - 0.11 11.9 1.6 12 5.3 0.1 3.5 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain FERM_N PF09379.5 EGO21823.1 - 0.15 12.1 0.1 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain AAA_5 PF07728.9 EGO21823.1 - 0.25 11.0 4.9 14 5.3 0.1 4.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Peptidase_M50B PF13398.1 EGO21824.1 - 1.7e-53 180.9 19.9 2.6e-53 180.4 13.8 1.2 1 0 0 1 1 1 1 Peptidase M50B-like DUF92 PF01940.11 EGO21824.1 - 1.9 7.5 13.6 1.4 8.0 0.1 3.1 3 0 0 3 3 3 0 Integral membrane protein DUF92 DUF202 PF02656.10 EGO21824.1 - 4.2 7.6 15.7 1.2e+03 -0.2 0.2 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) VCBS PF13517.1 EGO21825.1 - 4.3e-27 94.2 16.2 2e-09 37.6 0.2 5.2 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGO21825.1 - 3.8e-14 51.9 16.7 0.02 14.5 0.0 7.3 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EGO21825.1 - 0.00059 19.3 9.4 2.4 7.5 0.0 6.5 3 1 4 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region DUF718 PF05336.8 EGO21826.1 - 9.2e-30 102.5 0.2 1e-29 102.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Ras PF00071.17 EGO21827.1 - 1.8e-61 206.2 0.2 2.1e-61 206.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO21827.1 - 4.9e-21 75.4 0.1 7.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO21827.1 - 5.8e-13 48.4 0.0 7.5e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO21827.1 - 1.4e-07 31.4 0.1 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO21827.1 - 1.3e-05 24.6 0.1 5.7e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGO21827.1 - 2e-05 24.7 0.1 8.6e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EGO21827.1 - 0.00085 18.5 0.1 0.0014 17.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EGO21827.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGO21827.1 - 0.0032 16.7 0.1 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EGO21827.1 - 0.0097 15.1 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EGO21827.1 - 0.014 15.2 0.1 0.041 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EGO21827.1 - 0.021 13.9 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EGO21827.1 - 0.03 13.9 0.1 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGO21827.1 - 0.033 13.6 0.0 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EGO21827.1 - 0.035 14.3 0.1 0.057 13.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGO21827.1 - 0.044 13.7 0.2 0.096 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EGO21827.1 - 0.072 12.6 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.13 EGO21827.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 EGO21827.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 EGO21830.1 - 9.2e-59 193.3 14.4 1.9e-10 40.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGO21830.1 - 5.5e-08 32.7 0.4 2e-05 24.4 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGO21830.1 - 0.00034 19.4 0.1 3.1 6.4 0.0 3.7 1 1 3 4 4 4 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EGO21830.1 - 0.0015 17.4 0.0 0.0022 16.8 0.0 1.3 1 1 0 1 1 1 1 Coatomer WD associated region Apc4_WD40 PF12894.2 EGO21830.1 - 0.0031 16.9 0.0 0.54 9.8 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EGO21830.1 - 0.015 13.1 0.0 0.039 11.7 0.0 1.6 2 0 0 2 2 2 0 IKI3 family Det1 PF09737.4 EGO21830.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Nbas_N PF15492.1 EGO21830.1 - 0.047 12.7 0.3 6.1 5.8 0.0 3.6 3 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Histone PF00125.19 EGO21831.1 - 4.4e-28 97.2 1.3 4.4e-28 97.2 0.9 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO21831.1 - 3.9e-05 23.7 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGO21831.1 - 0.0017 17.6 0.4 0.002 17.4 0.2 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EGO21831.1 - 0.0026 17.7 0.2 0.0048 16.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO21831.1 - 0.023 14.4 0.1 0.04 13.6 0.1 1.4 1 1 0 1 1 1 0 Bromodomain associated PP2C PF00481.16 EGO21832.1 - 1.8e-17 63.6 0.0 1.6e-15 57.1 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGO21832.1 - 4.1e-06 26.3 0.0 7e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGO21832.1 - 0.019 14.6 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF4078 PF13300.1 EGO21832.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) IMS PF00817.15 EGO21833.1 - 2.9e-44 150.4 0.2 5.8e-44 149.4 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO21833.1 - 1.1e-13 51.1 0.0 2.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 EGO21833.1 - 5.4e-06 26.1 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EGO21833.1 - 7.5e-06 25.6 0.0 3.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.21 EGO21833.1 - 8.3e-05 22.6 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 EGO21833.1 - 0.0021 17.9 0.1 3.8 7.4 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) DUF1805 PF08827.6 EGO21833.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Methyltransf_23 PF13489.1 EGO21834.1 - 7.6e-16 58.2 0.0 1.1e-15 57.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO21834.1 - 2.9e-15 56.1 0.0 3.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO21834.1 - 7.6e-15 55.1 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO21834.1 - 8e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO21834.1 - 6.8e-10 39.5 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO21834.1 - 1.2e-09 38.4 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO21834.1 - 1.6e-06 27.3 0.1 3.6e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGO21834.1 - 2.5e-06 27.5 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGO21834.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 1 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EGO21834.1 - 0.0021 17.1 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EGO21834.1 - 0.0027 17.7 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EGO21834.1 - 0.0047 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGO21834.1 - 0.0082 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EGO21834.1 - 0.039 12.6 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EGO21834.1 - 0.044 13.4 0.1 0.092 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EGO21834.1 - 0.098 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) OPT PF03169.10 EGO21835.1 - 3.5e-196 653.3 56.2 4.2e-196 653.1 38.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Terpene_synth_C PF03936.11 EGO21839.1 - 6.4e-10 38.7 0.0 1.4e-09 37.6 0.0 1.5 1 1 1 2 2 2 2 Terpene synthase family, metal binding domain DUF4006 PF13179.1 EGO21840.1 - 0.08 12.5 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) EVC2_like PF12297.3 EGO21840.1 - 0.1 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein HMG_box PF00505.14 EGO21843.1 - 1.8e-09 37.7 6.3 4.5e-08 33.2 4.4 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO21843.1 - 0.00031 21.0 5.2 0.0015 18.8 3.6 2.0 1 1 0 1 1 1 1 HMG-box domain DUF1691 PF07950.6 EGO21844.1 - 2.2e-07 30.8 5.3 0.0016 18.3 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) 2OG-FeII_Oxy_3 PF13640.1 EGO21845.1 - 0.0014 19.1 0.2 0.0042 17.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fe_hyd_lg_C PF02906.9 EGO21845.1 - 0.033 13.4 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain 2OG-FeII_Oxy PF03171.15 EGO21845.1 - 0.034 14.4 0.3 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Cerato-platanin PF07249.7 EGO21846.1 - 9.2e-38 128.9 1.0 1.1e-37 128.6 0.7 1.0 1 0 0 1 1 1 1 Cerato-platanin DUF2914 PF11141.3 EGO21847.1 - 0.21 11.1 0.9 0.24 10.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Cerato-platanin PF07249.7 EGO21848.1 - 4.4e-42 142.8 1.6 5.2e-42 142.6 1.1 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 EGO21849.1 - 1.2e-39 134.9 0.9 1.7e-39 134.4 0.6 1.2 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 EGO21851.1 - 8.7e-41 138.6 2.3 1e-40 138.4 1.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 EGO21851.1 - 0.023 14.7 0.7 0.026 14.6 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Cerato-platanin PF07249.7 EGO21852.1 - 4.3e-10 39.6 0.1 5.6e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EGO21852.1 - 0.007 16.0 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Barwin family Med31 PF05669.7 EGO21852.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 SOH1 AMP-binding PF00501.23 EGO21853.1 - 6.5e-57 192.7 0.0 8.4e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO21853.1 - 1.3e-11 45.2 1.5 1.3e-11 45.2 1.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GST_N_3 PF13417.1 EGO21854.1 - 2.3e-12 46.9 0.0 6.3e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO21854.1 - 6.8e-09 35.5 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO21854.1 - 2.9e-05 24.1 0.0 6.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21854.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21854.1 - 0.031 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO21855.1 - 5.8e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21855.1 - 7.4e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO21855.1 - 2.6e-05 24.1 0.0 5.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO21855.1 - 0.0041 16.9 0.3 0.0067 16.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21855.1 - 0.0068 16.8 0.1 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO21855.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Rrp15p PF07890.7 EGO21856.1 - 3.2e-19 69.2 4.4 4.8e-18 65.4 3.0 2.0 1 1 0 1 1 1 1 Rrp15p Glyco_hydro_3 PF00933.16 EGO21859.1 - 3.6e-77 259.2 0.0 6.7e-77 258.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO21859.1 - 1.9e-68 230.3 0.0 4.2e-67 225.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO21859.1 - 1.1e-21 76.5 0.2 3e-21 75.1 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EGO21859.1 - 1.2e-08 34.6 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain NAD_binding_2 PF03446.10 EGO21860.1 - 2.2e-23 82.9 0.0 2.8e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGO21860.1 - 5.8e-07 29.8 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGO21860.1 - 7.5e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EGO21860.1 - 0.0063 16.8 0.0 0.88 9.8 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EGO21860.1 - 0.0069 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IlvN PF07991.7 EGO21860.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain OCD_Mu_crystall PF02423.10 EGO21860.1 - 0.034 12.8 0.0 0.062 12.0 0.0 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EGO21860.1 - 0.036 14.5 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_11 PF14833.1 EGO21860.1 - 0.092 12.8 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ABC_tran PF00005.22 EGO21861.1 - 3e-34 118.2 0.0 1e-33 116.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EGO21861.1 - 9.1e-30 103.9 11.6 1.3e-29 103.5 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGO21861.1 - 2.7e-07 30.8 0.1 0.0014 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO21861.1 - 0.00055 19.4 0.1 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGO21861.1 - 0.0032 16.5 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 EGO21861.1 - 0.0039 16.6 0.1 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EGO21861.1 - 0.0041 16.5 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGO21861.1 - 0.0072 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO21861.1 - 0.0074 16.2 0.2 0.016 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EGO21861.1 - 0.0089 15.8 0.3 0.02 14.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 T2SE PF00437.15 EGO21861.1 - 0.012 14.5 0.1 0.024 13.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EGO21861.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EGO21861.1 - 0.022 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGO21861.1 - 0.024 14.3 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EGO21861.1 - 0.034 13.7 0.0 0.087 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO21861.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO21861.1 - 0.037 14.8 0.0 0.078 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EGO21861.1 - 0.038 13.2 0.0 2.2 7.4 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 EGO21861.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGO21861.1 - 0.038 13.6 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EGO21861.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EGO21861.1 - 0.063 13.7 0.1 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EGO21861.1 - 0.085 13.0 0.1 0.34 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EGO21861.1 - 0.12 11.8 0.2 1.4 8.3 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.23 EGO21863.1 - 0.019 13.3 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme AMP-binding PF00501.23 EGO21864.1 - 0.042 12.2 0.0 0.043 12.2 0.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Poxvirus_B22R_N PF13169.1 EGO21869.1 - 0.14 12.4 0.1 0.14 12.3 0.1 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal Mso1_C PF14477.1 EGO21870.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 DUF3980 PF13140.1 EGO21870.1 - 0.4 10.9 4.7 0.75 10.1 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) PIG-F PF06699.6 EGO21870.1 - 0.46 10.3 6.3 0.69 9.8 0.4 2.5 2 1 0 2 2 2 0 GPI biosynthesis protein family Pig-F Sdh_cyt PF01127.17 EGO21870.1 - 7.6 6.3 10.1 17 5.2 1.3 2.6 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit AMP-binding PF00501.23 EGO21872.1 - 1.6e-98 329.8 0.0 2.5e-98 329.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGO21872.1 - 3.8e-61 206.7 0.1 1.1e-60 205.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EGO21872.1 - 3e-45 154.3 0.0 4.8e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EGO21872.1 - 6.5e-37 127.5 0.0 1.4e-36 126.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO21872.1 - 1.8e-36 125.5 0.1 9.2e-36 123.1 0.0 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 EGO21872.1 - 1e-30 106.0 0.1 1.6e-29 102.1 0.1 2.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGO21872.1 - 2e-30 105.8 0.1 7.4e-30 104.0 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EGO21872.1 - 1.2e-22 80.4 0.0 2.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EGO21872.1 - 9.5e-19 68.5 0.0 1.9e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EGO21872.1 - 2.2e-16 59.8 2.0 1.5e-08 34.7 0.0 4.0 4 0 0 4 4 4 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGO21872.1 - 7.8e-10 39.5 0.1 2.3e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 EGO21872.1 - 6.2e-09 36.0 0.1 2e-07 31.1 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 EGO21872.1 - 0.0006 19.3 0.0 0.0059 16.1 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 EGO21872.1 - 0.0006 19.5 1.4 0.011 15.4 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EGO21872.1 - 0.0023 16.9 0.3 0.006 15.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGO21872.1 - 0.0029 17.2 2.1 0.0033 17.0 0.2 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRR_8 PF13855.1 EGO21873.1 - 2.6e-07 30.2 7.6 0.19 11.4 0.0 5.7 3 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 EGO21873.1 - 1e-06 28.1 10.5 1.7 8.9 0.1 8.4 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.2 EGO21873.1 - 0.00028 20.4 8.1 1.9 8.2 0.1 5.6 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) Zn_Tnp_IS1595 PF12760.2 EGO21873.1 - 0.019 14.7 0.1 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain LRR_7 PF13504.1 EGO21873.1 - 1.3 9.5 15.2 87 4.0 0.2 7.2 7 2 2 9 9 9 0 Leucine rich repeat LRR_1 PF00560.28 EGO21873.1 - 1.6 9.0 9.6 60 4.2 0.0 6.4 9 0 0 9 9 9 0 Leucine Rich Repeat Pyr_redox_3 PF13738.1 EGO21874.1 - 1.4e-22 80.7 0.0 2.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO21874.1 - 1.1e-15 56.8 0.1 2.7e-14 52.2 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGO21874.1 - 3.3e-11 43.0 0.1 8e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO21874.1 - 6.2e-10 39.2 0.0 3.1e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO21874.1 - 1.2e-07 30.9 0.0 7e-05 21.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO21874.1 - 1.7e-05 24.6 0.5 0.00018 21.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EGO21874.1 - 4.3e-05 22.5 0.0 0.001 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Methyltransf_18 PF12847.2 EGO21874.1 - 0.018 15.5 0.0 0.14 12.7 0.0 2.4 2 2 0 2 2 2 0 Methyltransferase domain Pyr_redox PF00070.22 EGO21874.1 - 0.024 15.0 0.3 0.024 15.0 0.2 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO21874.1 - 0.044 12.6 0.3 0.064 12.0 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EGO21874.1 - 0.23 11.5 0.2 8.5 6.4 0.1 3.0 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EGO21875.1 - 3.5e-18 66.4 0.0 5.5e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO21875.1 - 2.8e-15 55.5 0.6 1.5e-13 49.7 0.5 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGO21875.1 - 1.2e-09 38.0 0.1 2.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGO21875.1 - 2.8e-09 36.3 0.2 6.2e-08 31.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO21875.1 - 4.2e-07 30.0 0.0 3e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO21875.1 - 5.8e-06 25.4 0.5 0.028 13.2 0.8 2.1 1 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EGO21875.1 - 0.011 14.8 0.3 0.024 13.7 0.2 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EGO21875.1 - 0.02 14.6 0.0 0.78 9.5 0.0 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 EGO21875.1 - 0.024 13.5 0.8 0.14 11.0 0.5 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EGO21875.1 - 0.086 11.6 0.8 3.1 6.5 0.3 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_25 PF01183.15 EGO21876.1 - 2.4e-51 174.1 2.8 2.7e-51 173.9 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 FAD_oxidored PF12831.2 EGO21877.1 - 0.00038 19.6 0.0 0.00099 18.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO21877.1 - 0.003 16.2 0.0 0.032 12.8 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Thaumatin PF00314.12 EGO21878.1 - 1.2e-14 54.2 11.9 1.5e-14 53.9 8.2 1.1 1 0 0 1 1 1 1 Thaumatin family FAD_oxidored PF12831.2 EGO21880.1 - 0.00029 20.0 0.0 0.0018 17.4 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO21880.1 - 0.00087 18.0 0.2 2.7 6.5 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase DAO PF01266.19 EGO21880.1 - 0.12 11.1 0.0 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase UPF0227 PF05728.7 EGO21881.1 - 0.00093 18.9 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 EGO21881.1 - 0.0066 16.3 0.0 0.0069 16.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO21881.1 - 0.03 13.5 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_oxidored PF12831.2 EGO21882.1 - 0.0073 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO21882.1 - 0.023 13.3 0.0 3.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase eIF2A PF08662.6 EGO21883.1 - 5.3e-78 261.1 0.0 1e-76 257.0 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGO21883.1 - 0.044 13.6 0.1 5.3 7.0 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat CDV3 PF15359.1 EGO21883.1 - 0.76 9.8 8.8 0.06 13.4 1.0 2.4 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.4 EGO21883.1 - 1.1 8.6 5.1 32 3.9 0.1 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Cellulase PF00150.13 EGO21884.1 - 1.8e-13 50.3 0.0 8.3e-10 38.3 0.1 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EGO21884.1 - 0.0043 16.4 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 OPA3 PF07047.7 EGO21885.1 - 8.1e-33 113.0 0.2 1.8e-32 111.9 0.0 1.5 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) CDC73 PF05179.9 EGO21886.1 - 7e-51 173.1 0.2 1.1e-50 172.4 0.1 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family GST_N_3 PF13417.1 EGO21887.1 - 7e-11 42.1 0.0 1.8e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO21887.1 - 3.3e-09 36.6 0.0 5.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO21887.1 - 1e-05 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21887.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO21887.1 - 0.00074 19.3 0.1 0.0015 18.4 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21887.1 - 0.012 16.0 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO21888.1 - 3.1e-08 33.7 0.0 1.1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO21888.1 - 8e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO21888.1 - 4.5e-05 23.3 0.0 0.00013 21.8 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO21888.1 - 0.00032 20.5 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO21888.1 - 0.0024 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO21888.1 - 0.014 15.9 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO21889.1 - 5.2e-06 26.3 0.0 6.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO21889.1 - 0.00085 19.1 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO21889.1 - 0.005 17.2 0.2 0.007 16.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.23 EGO21890.1 - 1.9e-33 115.5 0.0 1.1e-30 106.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF904 PF06005.7 EGO21891.1 - 1.8e-05 24.9 4.5 1.8e-05 24.9 3.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF904) PspA_IM30 PF04012.7 EGO21891.1 - 0.0061 15.9 2.8 0.0061 15.9 1.9 1.3 1 1 0 1 1 1 1 PspA/IM30 family Jnk-SapK_ap_N PF09744.4 EGO21891.1 - 0.018 15.0 4.8 0.022 14.7 3.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 EGO21891.1 - 0.065 12.7 3.7 0.056 12.9 1.5 1.8 1 1 0 1 1 1 0 Septum formation initiator Prominin PF05478.6 EGO21891.1 - 0.11 10.0 5.5 0.11 9.9 3.8 1.0 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 EGO21891.1 - 0.12 12.7 5.8 0.15 12.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 EGO21891.1 - 0.12 11.2 2.2 0.13 11.2 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 EGO21891.1 - 0.13 11.9 8.5 0.48 10.1 5.9 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 EGO21891.1 - 0.15 11.0 7.3 0.17 10.9 5.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 GlutR_dimer PF00745.15 EGO21891.1 - 0.16 11.9 2.4 0.2 11.6 1.7 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain CENP-F_leu_zip PF10473.4 EGO21891.1 - 0.19 11.5 10.7 2.3 8.0 5.2 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps51 PF08700.6 EGO21891.1 - 0.2 11.4 3.5 2 8.3 1.9 2.4 1 1 0 1 1 1 0 Vps51/Vps67 FlxA PF14282.1 EGO21891.1 - 0.22 11.4 4.8 0.24 11.3 2.7 1.6 1 1 1 2 2 2 0 FlxA-like protein TMF_DNA_bd PF12329.3 EGO21891.1 - 0.25 11.1 10.8 0.43 10.4 7.1 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YlqD PF11068.3 EGO21891.1 - 0.28 11.2 5.4 0.34 10.9 1.3 2.0 1 1 0 1 1 1 0 YlqD protein Herpes_UL6 PF01763.11 EGO21891.1 - 0.72 7.9 5.4 0.87 7.6 3.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF2968 PF11180.3 EGO21891.1 - 0.73 9.1 8.1 0.91 8.8 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4164 PF13747.1 EGO21891.1 - 1.4 9.0 9.3 4.5 7.4 6.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Sec20 PF03908.8 EGO21891.1 - 1.5 8.5 4.6 4 7.2 3.2 1.8 1 1 0 1 1 1 0 Sec20 zf-C4H2 PF10146.4 EGO21891.1 - 1.9 8.4 5.8 2 8.4 4.0 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein IFP_35_N PF07334.8 EGO21891.1 - 4 7.4 5.9 10 6.1 0.3 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus IncA PF04156.9 EGO21891.1 - 5 6.6 7.6 5.8 6.4 5.2 1.1 1 0 0 1 1 1 0 IncA protein Aldolase_II PF00596.16 EGO21892.1 - 3.4e-37 127.8 0.0 3.9e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.20 EGO21893.1 - 5.7e-40 137.1 0.0 1.1e-22 80.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21893.1 - 1.1e-14 54.1 0.5 3.1e-07 29.7 0.1 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGO21893.1 - 0.096 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Asp PF00026.18 EGO21894.1 - 1.8e-76 257.3 6.8 2.1e-76 257.2 4.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO21894.1 - 4e-06 26.8 5.0 7.7e-06 25.9 2.2 2.3 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO21894.1 - 0.021 15.3 3.4 0.65 10.5 0.4 2.9 2 1 0 2 2 2 0 Aspartyl protease Mg_trans_NIPA PF05653.9 EGO21895.1 - 1.2e-17 63.8 12.1 5.1e-11 42.0 0.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA IncA PF04156.9 EGO21896.1 - 0.00014 21.5 22.1 0.00073 19.1 11.3 2.2 2 0 0 2 2 2 2 IncA protein DUF342 PF03961.8 EGO21896.1 - 0.0048 15.3 17.6 0.045 12.1 7.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF342) CASP_C PF08172.7 EGO21896.1 - 0.013 14.5 23.9 0.032 13.2 3.3 3.4 2 1 1 3 3 3 0 CASP C terminal DUF4201 PF13870.1 EGO21896.1 - 0.032 13.6 24.8 0.12 11.8 10.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) TMCO5 PF14992.1 EGO21896.1 - 0.11 11.5 23.0 0.11 11.6 11.5 2.3 2 0 0 2 2 2 0 TMCO5 family DUF972 PF06156.8 EGO21896.1 - 0.13 12.6 22.0 0.041 14.2 2.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4164 PF13747.1 EGO21896.1 - 0.87 9.7 18.8 0.29 11.2 2.8 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) ADIP PF11559.3 EGO21896.1 - 0.94 9.3 31.9 1.1 9.2 6.2 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 EGO21896.1 - 1.5 8.2 31.8 0.0077 15.7 10.5 2.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 EGO21896.1 - 4.2 7.2 33.2 1.3 8.9 4.3 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EGO21896.1 - 4.6 7.3 21.5 3.6 7.6 2.2 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 EGO21896.1 - 6.1 6.1 17.0 1 8.6 0.8 3.1 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Mnd1 PF03962.10 EGO21896.1 - 7 6.2 29.2 4 7.0 0.7 3.4 2 1 2 4 4 4 0 Mnd1 family Reo_sigmaC PF04582.7 EGO21896.1 - 7 5.7 13.2 5.6 6.0 0.6 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 EGO21896.1 - 10 5.0 32.3 1.4 7.9 6.7 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 O-FucT PF10250.4 EGO21897.1 - 3.1e-13 49.5 0.0 6.2e-06 25.5 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase UDPGT PF00201.13 EGO21898.1 - 0.0013 17.3 0.2 0.0017 17.0 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGO21898.1 - 0.003 17.2 0.1 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Hist_deacetyl PF00850.14 EGO21900.1 - 5.1e-79 265.7 0.4 6.8e-79 265.3 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Per1 PF04080.8 EGO21901.1 - 5.6e-91 304.6 10.6 7.2e-91 304.3 7.4 1.1 1 0 0 1 1 1 1 Per1-like DPCD PF14913.1 EGO21902.1 - 0.05 12.7 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 DPCD protein family Pribosyltran_N PF13793.1 EGO21903.1 - 2.6e-51 172.2 0.1 2.2e-48 162.8 0.0 2.6 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGO21903.1 - 1.2e-34 119.7 0.6 2.3e-30 105.6 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGO21903.1 - 6.4e-14 51.7 0.2 4.6e-13 48.9 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO21903.1 - 0.00086 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_kinase PF00696.23 EGO21904.1 - 9.3e-39 133.4 1.0 1.3e-38 132.8 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EGO21904.1 - 1.4e-08 34.3 0.0 0.00059 19.5 0.0 2.6 2 0 0 2 2 2 2 PUA domain Cupin_2 PF07883.6 EGO21905.1 - 2e-07 30.3 0.5 4.1e-07 29.4 0.4 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGO21905.1 - 0.018 14.7 0.1 0.054 13.1 0.1 1.7 1 1 1 2 2 2 0 AraC-like ligand binding domain DOPA_dioxygen PF08883.6 EGO21906.1 - 3.1e-28 97.8 0.0 3.9e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glycos_transf_1 PF00534.15 EGO21907.1 - 1.2e-19 70.3 0.0 4.5e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGO21907.1 - 2.1e-10 40.5 0.0 2e-09 37.4 0.0 2.4 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGO21907.1 - 8.2e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EGO21907.1 - 0.0022 18.1 0.0 0.019 15.1 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferases group 1 DUF1145 PF06611.7 EGO21907.1 - 0.036 13.6 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) GIIM PF08388.6 EGO21910.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Group II intron, maturase-specific domain DUF1014 PF06244.7 EGO21911.1 - 2.1e-21 76.4 17.4 7.3e-18 64.9 1.4 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1014) DUF2639 PF11121.3 EGO21911.1 - 0.65 9.5 4.2 12 5.4 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2639) Borrelia_P83 PF05262.6 EGO21911.1 - 1.2 7.3 13.9 1.8 6.7 9.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Lipase_GDSL PF00657.17 EGO21912.1 - 1.8e-17 63.9 0.1 2.2e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGO21912.1 - 9.8e-06 25.8 1.5 3.5e-05 24.0 1.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NACHT PF05729.7 EGO21913.1 - 7e-05 22.5 0.0 0.00023 20.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO21913.1 - 0.028 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EGO21913.1 - 0.05 13.3 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 EGO21913.1 - 0.069 12.1 0.2 0.33 9.9 0.2 1.9 1 1 1 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.15 EGO21913.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase HET PF06985.6 EGO21914.1 - 1.9e-24 86.4 0.0 3.3e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fer2_2 PF01799.15 EGO21914.1 - 0.15 11.9 0.4 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 [2Fe-2S] binding domain Calcipressin PF04847.7 EGO21915.1 - 1.6e-29 102.8 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Calcipressin SUR7 PF06687.7 EGO21917.1 - 2.1 7.8 7.3 1.2 8.6 0.5 2.1 2 0 0 2 2 2 0 SUR7/PalI family Pkinase PF00069.20 EGO21918.1 - 8e-32 110.4 0.0 3.4e-31 108.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21918.1 - 3.2e-15 55.9 0.0 3.9e-13 49.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO21918.1 - 3.6e-05 22.8 0.0 0.0055 15.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGO21918.1 - 0.0017 17.4 0.0 0.0034 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO21918.1 - 0.0068 16.1 1.1 0.072 12.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CbiQ PF02361.11 EGO21919.1 - 0.53 9.8 6.5 0.65 9.5 4.5 1.1 1 0 0 1 1 1 0 Cobalt transport protein NR_Repeat PF14046.1 EGO21920.1 - 0.12 12.0 1.4 0.13 11.9 0.6 1.4 1 1 0 1 1 1 0 Nuclear receptor repeat DUF4233 PF14017.1 EGO21923.1 - 0.00075 19.3 3.0 0.24 11.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4233) COX17 PF05051.8 EGO21924.1 - 2.7e-19 68.9 2.2 3.5e-19 68.5 1.5 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) WD40 PF00400.27 EGO21925.1 - 1.5e-15 56.3 4.6 5.4e-11 41.9 0.1 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nbas_N PF15492.1 EGO21925.1 - 0.072 12.1 0.0 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 EGO21926.1 - 1.8e-21 75.1 2.0 8.2e-10 38.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 EGO21926.1 - 0.0014 18.4 1.0 0.01 15.6 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO21926.1 - 0.0033 17.4 1.2 0.0089 16.0 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO21926.1 - 0.048 13.3 3.3 0.13 11.8 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGO21926.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.1 EGO21926.1 - 0.097 12.4 3.9 0.4 10.4 2.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain EF-hand_4 PF12763.2 EGO21927.1 - 9e-14 51.0 0.0 8.6e-09 35.0 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand ATP-synt_DE PF00401.15 EGO21929.1 - 0.061 13.2 1.6 0.12 12.2 1.1 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Phage_holin_T PF11031.3 EGO21931.1 - 0.13 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T holin Glyoxalase_3 PF13468.1 EGO21933.1 - 7.1e-30 104.1 0.0 3e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Med18 PF09637.5 EGO21933.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Med18 protein Asp PF00026.18 EGO21934.1 - 3.5e-43 148.0 5.7 4.8e-31 108.1 0.2 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGO21934.1 - 0.00018 21.0 0.1 0.00045 19.8 0.0 1.7 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.18 EGO21935.1 - 6.1e-78 262.2 6.1 7e-78 262.0 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGO21935.1 - 2.8e-06 26.9 0.0 6.4e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EGO21935.1 - 0.012 16.1 1.8 0.35 11.3 0.1 3.2 2 2 0 2 2 2 0 Aspartyl protease MAP65_ASE1 PF03999.7 EGO21936.1 - 0.00015 20.5 4.9 0.00016 20.4 3.4 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) IncA PF04156.9 EGO21936.1 - 0.00047 19.8 4.3 0.00047 19.8 3.0 2.0 1 1 1 2 2 2 1 IncA protein WEMBL PF05701.6 EGO21936.1 - 0.00058 18.4 9.8 0.0032 15.9 6.6 1.8 1 1 1 2 2 2 1 Weak chloroplast movement under blue light CCDC155 PF14662.1 EGO21936.1 - 0.0018 17.9 11.1 0.022 14.3 5.1 2.4 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 EGO21936.1 - 0.0021 17.9 11.1 0.003 17.4 3.8 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCPsignal PF00015.16 EGO21936.1 - 0.0035 16.9 2.1 0.023 14.2 0.0 2.2 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TMF_TATA_bd PF12325.3 EGO21936.1 - 0.0058 16.3 5.4 0.0058 16.3 3.8 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Cluap1 PF10234.4 EGO21936.1 - 0.0063 15.7 4.5 0.0074 15.5 3.1 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF2400 PF09674.5 EGO21936.1 - 0.0068 16.1 1.3 0.7 9.5 0.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2400) APG6 PF04111.7 EGO21936.1 - 0.0071 15.4 12.4 0.044 12.8 1.2 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 CALCOCO1 PF07888.6 EGO21936.1 - 0.0075 14.6 9.7 0.011 14.1 6.8 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.3 EGO21936.1 - 0.0076 13.6 10.4 0.0096 13.3 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CCDC144C PF14915.1 EGO21936.1 - 0.01 14.7 10.0 0.016 14.1 6.9 1.3 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF972 PF06156.8 EGO21936.1 - 0.011 16.0 9.6 0.23 11.8 4.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2422 PF10337.4 EGO21936.1 - 0.011 14.5 5.2 0.014 14.2 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF904 PF06005.7 EGO21936.1 - 0.012 15.9 10.2 0.38 11.0 0.8 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF904) TBPIP PF07106.8 EGO21936.1 - 0.016 14.7 9.0 0.055 13.0 4.1 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EGO21936.1 - 0.018 13.7 7.6 0.035 12.7 5.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EGO21936.1 - 0.023 14.4 6.0 0.76 9.6 1.1 2.9 2 1 0 3 3 2 0 TATA element modulatory factor 1 DNA binding RmuC PF02646.11 EGO21936.1 - 0.024 13.4 6.0 0.033 13.0 0.3 2.1 1 1 1 2 2 2 0 RmuC family Reo_sigmaC PF04582.7 EGO21936.1 - 0.025 13.7 0.3 0.04 13.0 0.2 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein SYCE1 PF15233.1 EGO21936.1 - 0.033 14.1 11.4 0.25 11.2 7.2 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DASH_Duo1 PF08651.5 EGO21936.1 - 0.034 13.7 3.0 0.2 11.2 0.1 3.2 1 1 1 3 3 3 0 DASH complex subunit Duo1 DUF3391 PF11871.3 EGO21936.1 - 0.065 13.4 0.6 0.065 13.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4404 PF14357.1 EGO21936.1 - 0.069 13.5 7.0 4 7.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Rab5-bind PF09311.6 EGO21936.1 - 0.094 12.5 15.7 0.23 11.3 10.9 1.7 1 1 0 1 1 1 0 Rabaptin-like protein EzrA PF06160.7 EGO21936.1 - 0.097 10.8 9.8 0.015 13.4 1.1 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Seryl_tRNA_N PF02403.17 EGO21936.1 - 0.098 12.6 6.7 0.28 11.2 2.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DegS PF05384.6 EGO21936.1 - 0.1 11.8 7.5 0.8 8.9 0.7 2.5 1 1 1 2 2 2 0 Sensor protein DegS Rabaptin PF03528.10 EGO21936.1 - 0.11 12.4 12.7 0.13 12.1 0.5 3.0 1 1 2 3 3 3 0 Rabaptin Cep57_CLD_2 PF14197.1 EGO21936.1 - 0.12 12.3 18.1 0.059 13.3 2.4 3.5 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Laminin_I PF06008.9 EGO21936.1 - 0.13 11.5 10.5 0.065 12.5 1.1 2.6 1 1 2 3 3 3 0 Laminin Domain I V_ATPase_I PF01496.14 EGO21936.1 - 0.18 9.6 2.9 0.24 9.2 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C6 PF00851.13 EGO21936.1 - 0.22 10.1 2.5 0.26 9.8 1.6 1.2 1 1 0 1 1 1 0 Helper component proteinase ATG16 PF08614.6 EGO21936.1 - 0.26 11.1 12.9 55 3.4 9.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 EGO21936.1 - 0.27 10.4 10.7 0.52 9.4 2.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Zwint PF15556.1 EGO21936.1 - 0.29 10.3 8.4 0.17 11.0 4.6 1.5 1 1 0 1 1 1 0 ZW10 interactor IFP_35_N PF07334.8 EGO21936.1 - 0.3 11.1 2.5 6.4 6.8 0.2 2.6 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus T2SF PF00482.18 EGO21936.1 - 0.34 10.8 4.6 0.81 9.6 0.6 2.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Mnd1 PF03962.10 EGO21936.1 - 0.37 10.4 10.5 1.1 8.9 1.4 2.1 1 1 1 2 2 2 0 Mnd1 family Occludin_ELL PF07303.8 EGO21936.1 - 0.47 11.2 7.5 3.6 8.3 0.4 2.9 1 1 2 3 3 3 0 Occludin homology domain HAUS-augmin3 PF14932.1 EGO21936.1 - 0.62 9.1 10.0 1.4 8.0 1.6 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DivIVA PF05103.8 EGO21936.1 - 0.68 9.9 11.3 1.6 8.7 0.5 2.8 1 1 2 3 3 3 0 DivIVA protein ADIP PF11559.3 EGO21936.1 - 0.72 9.7 11.7 0.46 10.3 1.3 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SbcD_C PF12320.3 EGO21936.1 - 0.72 9.9 3.4 0.85 9.6 0.3 2.2 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain DUF2968 PF11180.3 EGO21936.1 - 0.75 9.1 11.9 0.08 12.3 4.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) UPF0242 PF06785.6 EGO21936.1 - 0.78 8.3 8.2 1.2 7.6 5.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) FUSC PF04632.7 EGO21936.1 - 1 7.6 9.0 1.2 7.4 6.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 EGO21936.1 - 1.1 7.6 6.3 1.7 6.9 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DASH_Hsk3 PF08227.6 EGO21936.1 - 1.4 9.1 7.6 11 6.2 0.0 3.4 4 0 0 4 4 2 0 DASH complex subunit Hsk3 like EMP24_GP25L PF01105.19 EGO21936.1 - 1.4 8.5 4.6 8.6 6.0 0.0 2.5 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD Nup54 PF13874.1 EGO21936.1 - 1.7 8.2 8.1 0.49 10.0 2.9 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CENP-Q PF13094.1 EGO21936.1 - 3 7.8 11.7 6.2 6.8 8.1 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 EGO21936.1 - 4.2 6.2 10.6 3 6.7 1.6 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EGO21936.1 - 5.9 6.6 7.7 12 5.6 0.5 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.7 EGO21936.1 - 8 6.6 9.5 1.8 8.7 3.7 2.0 2 2 0 2 2 2 0 Centromere protein H (CENP-H) V-SNARE PF05008.10 EGO21936.1 - 8 6.6 8.7 2 8.6 0.4 3.0 3 2 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus HALZ PF02183.13 EGO21936.1 - 8.9 6.1 11.0 6.2 6.6 0.0 3.6 3 1 1 4 4 3 0 Homeobox associated leucine zipper Ada3 PF10198.4 EGO21937.1 - 7.9e-24 83.8 0.0 7.9e-24 83.8 0.0 3.0 4 0 0 4 4 4 1 Histone acetyltransferases subunit 3 MgtE PF01769.11 EGO21938.1 - 3e-26 92.2 28.0 5.7e-10 39.6 2.2 4.0 3 1 1 4 4 4 3 Divalent cation transporter DUF2771 PF10969.3 EGO21939.1 - 0.028 13.6 0.4 0.037 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) RNA_polI_A34 PF08208.6 EGO21940.1 - 1.2e-08 34.8 4.6 1.2e-08 34.8 3.2 2.6 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Phos_pyr_kin PF08543.7 EGO21941.1 - 1.4e-84 283.1 0.1 3.3e-83 278.6 0.1 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EGO21941.1 - 3.3e-39 134.8 0.0 5e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EGO21941.1 - 0.00049 19.3 0.1 0.0074 15.4 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HhH-GPD PF00730.20 EGO21942.1 - 5.6e-21 74.8 0.0 9.7e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGO21942.1 - 4.3e-08 32.4 0.0 9.8e-08 31.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RseC_MucC PF04246.7 EGO21942.1 - 0.0011 18.4 0.1 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC HHH_5 PF14520.1 EGO21942.1 - 0.005 16.9 0.1 0.21 11.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain STE2 PF02116.10 EGO21943.1 - 0.0073 15.3 13.6 0.12 11.3 9.4 2.1 1 1 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR 3Beta_HSD PF01073.14 EGO21944.1 - 2.1e-67 226.8 0.0 2.5e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO21944.1 - 3.2e-32 111.8 0.0 4.4e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO21944.1 - 4.6e-16 58.5 0.0 6.5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO21944.1 - 4.3e-13 49.6 0.0 6.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO21944.1 - 1.3e-10 40.6 0.1 3e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EGO21944.1 - 4.9e-07 28.9 0.1 3.4e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EGO21944.1 - 3e-05 23.7 0.4 0.00038 20.1 0.3 2.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EGO21944.1 - 3.8e-05 23.6 0.3 0.00019 21.4 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EGO21944.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 EGO21944.1 - 0.028 13.6 0.1 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 NmrA-like family NAD_binding_3 PF03447.11 EGO21944.1 - 0.045 14.1 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Mak10 PF04112.8 EGO21945.1 - 1.8e-34 118.3 0.0 3e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.20 EGO21946.1 - 2.5e-72 243.4 0.0 3.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MRP-S33 PF08293.6 EGO21948.1 - 6.5e-25 86.9 0.5 8.1e-25 86.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SUV3_C PF12513.3 EGO21950.1 - 8e-12 44.4 0.5 2.2e-11 42.9 0.3 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EGO21950.1 - 3e-08 33.4 0.0 5.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain p450 PF00067.17 EGO21951.1 - 3.1e-09 35.8 0.0 6.5e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 EGO21952.1 - 4.9e-05 23.2 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO21952.1 - 0.0092 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGO21952.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.1 EGO21952.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 EGO21954.1 - 1e-27 97.1 0.3 5.5e-27 94.7 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO21954.1 - 7.1e-14 52.1 0.2 1.4e-13 51.1 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO21954.1 - 3e-09 36.7 0.0 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EGO21954.1 - 4.2e-05 23.6 0.6 0.0003 20.8 0.2 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EGO21954.1 - 0.00071 19.9 0.8 0.0014 18.9 0.6 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 EGO21954.1 - 0.0042 16.1 0.1 0.007 15.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EGO21954.1 - 0.0071 16.0 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EGO21954.1 - 0.0084 15.0 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO21954.1 - 0.0088 16.0 0.9 0.011 15.7 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO21954.1 - 0.025 14.0 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EGO21954.1 - 0.028 14.2 0.6 0.057 13.2 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NmrA PF05368.8 EGO21954.1 - 0.054 12.7 0.2 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EGO21954.1 - 0.082 12.6 3.1 0.22 11.3 1.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IPK PF03770.11 EGO21956.1 - 1.6e-43 148.6 0.0 2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CENP-B_dimeris PF09026.5 EGO21956.1 - 0.032 14.4 7.7 0.058 13.6 5.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.3 EGO21956.1 - 0.043 13.7 4.5 0.064 13.1 3.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 p450 PF00067.17 EGO21957.1 - 3.8e-42 144.3 0.0 5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EGO21958.1 - 3.1e-29 101.5 0.0 2.4e-28 98.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO21958.1 - 4e-14 52.6 0.0 8.4e-14 51.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO21958.1 - 2.4e-10 39.7 0.0 1.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGO21958.1 - 1e-05 25.6 0.0 5.7e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO21958.1 - 6.5e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGO21958.1 - 7.8e-05 22.6 0.3 0.00017 21.5 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO21958.1 - 0.00028 19.9 0.0 0.0063 15.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ABC_membrane PF00664.18 EGO21959.1 - 4.6e-78 262.4 32.0 1.1e-40 139.8 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO21959.1 - 1.3e-65 219.8 0.0 4.7e-32 111.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGO21959.1 - 1.4e-14 53.8 0.2 9.9e-05 21.6 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO21959.1 - 3.5e-12 46.9 0.0 3.6e-05 23.8 0.0 4.4 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EGO21959.1 - 3.2e-09 35.9 0.5 0.00029 19.5 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGO21959.1 - 7.6e-09 34.9 1.5 0.0037 16.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO21959.1 - 5.2e-07 30.5 0.0 0.064 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGO21959.1 - 4e-06 26.0 0.0 0.093 11.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO21959.1 - 9.9e-06 25.6 1.3 0.06 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.15 EGO21959.1 - 1.5e-05 23.8 0.0 0.0034 16.1 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 EGO21959.1 - 0.0001 22.4 0.7 1.9 8.6 0.2 4.2 3 2 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGO21959.1 - 0.00015 21.6 6.1 0.071 13.0 0.2 3.8 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGO21959.1 - 0.0004 20.2 0.0 1.2 8.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGO21959.1 - 0.00078 19.8 0.3 0.35 11.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO21959.1 - 0.00085 19.6 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGO21959.1 - 0.00098 18.5 0.1 1.6 8.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EGO21959.1 - 0.0024 17.4 0.1 3.3 7.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EGO21959.1 - 0.0071 15.8 0.5 1.3 8.3 0.0 3.3 4 0 0 4 4 4 1 AAA-like domain MobB PF03205.9 EGO21959.1 - 0.0096 15.6 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EGO21959.1 - 0.015 15.0 0.0 7.1 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGO21959.1 - 0.018 15.2 0.0 7.4 6.8 0.0 3.5 3 0 0 3 3 3 0 RNA helicase DUF87 PF01935.12 EGO21959.1 - 0.02 14.7 4.0 0.29 10.9 0.0 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EGO21959.1 - 0.03 13.3 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGO21959.1 - 0.068 13.1 0.0 11 6.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EGO21959.1 - 0.09 12.4 0.0 22 4.6 0.0 2.9 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EGO21959.1 - 0.11 11.9 0.2 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family 3Beta_HSD PF01073.14 EGO21960.1 - 3.1e-29 101.5 0.0 2.4e-28 98.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO21960.1 - 4e-14 52.6 0.0 8.4e-14 51.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO21960.1 - 2.4e-10 39.7 0.0 1.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGO21960.1 - 1e-05 25.6 0.0 5.7e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO21960.1 - 6.5e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGO21960.1 - 7.8e-05 22.6 0.3 0.00017 21.5 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO21960.1 - 0.00028 19.9 0.0 0.0063 15.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Retrotrans_gag PF03732.12 EGO21964.1 - 9.5e-08 32.0 1.1 3e-07 30.4 0.3 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO21964.1 - 1.1e-07 31.4 2.9 2.3e-07 30.3 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Nif11 PF07862.6 EGO21964.1 - 0.036 14.0 0.2 0.12 12.3 0.2 1.9 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function Helicase_C PF00271.26 EGO21966.1 - 7.5e-13 48.1 0.0 1.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO21966.1 - 1.9e-05 24.2 0.0 0.002 17.6 0.1 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EGO21966.1 - 0.0015 17.1 0.0 0.0024 16.5 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Dicty_CAD PF05720.7 EGO21967.1 - 0.16 11.6 0.7 0.35 10.5 0.4 1.6 1 1 1 2 2 2 0 Cell-cell adhesion domain RhoGEF PF00621.15 EGO21969.1 - 2.7e-44 151.2 2.1 4.1e-44 150.6 1.4 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 EGO21969.1 - 1.4e-20 72.3 1.0 1.7e-11 43.2 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EGO21969.1 - 2.9e-19 68.3 2.0 3.2e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EGO21969.1 - 2e-11 43.1 0.0 4e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PH PF00169.24 EGO21969.1 - 0.026 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 PH domain YL1 PF05764.8 EGO21969.1 - 0.078 12.5 3.9 0.15 11.6 2.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EGO21969.1 - 0.16 10.0 1.9 0.23 9.4 1.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGO21969.1 - 0.19 9.6 3.9 0.36 8.7 2.7 1.4 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EGO21969.1 - 1 8.2 6.2 2.2 7.1 4.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit F-box-like PF12937.2 EGO21970.1 - 0.0043 16.7 1.6 0.0043 16.7 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGO21970.1 - 0.017 14.7 3.4 0.023 14.3 0.3 2.6 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.28 EGO21970.1 - 0.23 11.6 2.6 4.4 7.7 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EGO21970.1 - 0.3 11.4 7.4 6.1 7.5 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 EGO21970.1 - 0.31 10.8 6.6 11 5.9 0.0 4.0 5 0 0 5 5 5 0 Leucine rich repeat TFIIA PF03153.8 EGO21972.1 - 0.091 12.6 8.7 0.13 12.1 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit INCENP_N PF12178.3 EGO21976.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal Pkinase PF00069.20 EGO21977.1 - 2.8e-06 26.6 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGO21977.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EGO21977.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO21977.1 - 0.0047 16.6 0.1 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO21977.1 - 0.027 13.8 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 EGO21977.1 - 0.083 12.0 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase ubiquitin PF00240.18 EGO21978.1 - 0.049 13.0 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family DapB_C PF05173.9 EGO21981.1 - 0.14 11.9 0.5 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, C-terminus Sec63 PF02889.11 EGO21982.1 - 4.9e-09 35.8 0.0 1.8e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain zf-CCHC PF00098.18 EGO21984.1 - 1.2e-07 31.3 3.1 2.4e-07 30.3 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO21984.1 - 1.8e-06 27.8 0.7 5.5e-06 26.3 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.1 EGO21984.1 - 0.14 11.6 0.8 0.27 10.7 0.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EGO21984.1 - 2.8 7.7 6.3 1.3 8.8 2.4 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF2890 PF11081.3 EGO21986.1 - 0.097 12.7 9.0 0.82 9.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EGO21986.1 - 0.34 8.7 13.7 0.5 8.2 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EGO21986.1 - 0.77 8.7 15.2 1.2 8.1 10.6 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.3 EGO21986.1 - 4.2 7.2 17.7 0.52 10.2 1.9 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 zf-met PF12874.2 EGO21987.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-CCHC PF00098.18 EGO21989.1 - 1.3e-07 31.1 3.8 2.8e-07 30.1 2.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO21989.1 - 1.4e-06 28.3 0.7 4.1e-06 26.7 0.2 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO21989.1 - 4.8 7.0 8.3 2.7 7.7 3.7 2.1 2 1 0 2 2 2 0 Zinc knuckle Sec2p PF06428.6 EGO21990.1 - 0.04 13.7 0.5 0.062 13.1 0.3 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Rap1_C PF11626.3 EGO21991.1 - 0.0027 17.5 0.5 0.013 15.4 0.1 2.2 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nucleoplasmin PF03066.10 EGO21991.1 - 0.046 13.2 0.7 0.071 12.6 0.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Arb1 PF09692.5 EGO21993.1 - 4.8e-05 22.3 0.1 0.00017 20.5 0.0 1.8 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Glyco_hydro_31 PF01055.21 EGO21994.1 - 3.8e-159 530.2 4.5 4.8e-159 529.8 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO21994.1 - 3.8e-11 42.6 1.2 1.1e-10 41.1 0.4 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like PP2C PF00481.16 EGO21995.1 - 2.5e-31 108.9 0.0 6.7e-31 107.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGO21995.1 - 9.9e-06 25.3 0.0 0.0051 16.5 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGO21995.1 - 0.00041 19.8 0.0 0.00085 18.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 EGO21998.1 - 5.3e-51 173.2 0.0 8.3e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO21998.1 - 3e-24 85.4 0.0 6e-24 84.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGO21998.1 - 0.0031 16.3 0.1 0.005 15.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EGO21998.1 - 0.014 14.7 0.9 0.89 8.8 0.6 2.4 1 1 0 1 1 1 0 RIO1 family Cyclase PF04199.8 EGO21999.1 - 4.2e-14 52.5 0.0 6.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Shugoshin_C PF07557.6 EGO22000.1 - 2e-08 33.5 4.2 2e-08 33.5 2.9 2.9 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.6 EGO22000.1 - 2.5e-05 23.8 3.0 5.7e-05 22.7 2.1 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF1680 PF07944.7 EGO22001.1 - 0.071 11.3 0.3 0.076 11.2 0.2 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Ku_C PF03730.9 EGO22001.1 - 0.93 10.0 9.5 0.65 10.5 4.7 1.8 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm SPACA7 PF15307.1 EGO22001.1 - 2 8.6 7.0 0.54 10.3 0.8 2.3 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 MFS_1 PF07690.11 EGO22006.1 - 1e-46 159.2 43.0 1.2e-44 152.4 29.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO22006.1 - 2.6e-09 35.8 11.0 4.5e-09 35.0 7.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO22006.1 - 0.00014 20.3 3.9 0.00014 20.3 2.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF3357 PF11837.3 EGO22006.1 - 0.037 13.8 1.1 17 5.2 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) WTF PF03303.8 EGO22006.1 - 0.16 11.3 0.5 0.28 10.5 0.4 1.4 1 0 0 1 1 1 0 WTF protein Omega_Repress PF07764.6 EGO22013.1 - 0.043 14.1 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Omega Transcriptional Repressor GATase_4 PF13230.1 EGO22013.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II MFS_1 PF07690.11 EGO22014.1 - 4.2e-19 68.4 16.3 4.2e-19 68.4 11.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EGO22014.1 - 0.0017 16.4 0.3 0.0027 15.8 0.2 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DNase_NucA_NucB PF14040.1 EGO22015.1 - 0.083 13.0 0.1 0.095 12.8 0.0 1.1 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB C2 PF00168.25 EGO22016.1 - 1.6e-14 53.4 0.1 2.7e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 C2 domain Pollen_allerg_1 PF01357.16 EGO22016.1 - 0.093 12.5 0.0 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Pollen allergen MFS_1 PF07690.11 EGO22017.1 - 2.6e-40 138.2 29.4 2.6e-40 138.2 20.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO22017.1 - 2.1e-09 36.5 9.5 2.1e-09 36.5 6.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DZR PF12773.2 EGO22018.1 - 0.31 10.8 9.3 1.4 8.8 6.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGO22018.1 - 2.8 7.2 9.7 2 7.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SOG2 PF10428.4 EGO22018.1 - 4.6 5.7 6.5 6.1 5.3 4.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein APOC4 PF15119.1 EGO22020.1 - 0.94 9.4 5.8 64 3.6 1.3 3.6 3 2 1 4 4 4 0 Apolipoprotein C4 Phytase PF02333.10 EGO22022.1 - 0.055 12.1 0.0 0.06 12.0 0.0 1.0 1 0 0 1 1 1 0 Phytase MFS_1 PF07690.11 EGO22023.1 - 8.3e-36 123.4 25.4 1e-35 123.1 17.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO22023.1 - 1.1e-10 40.7 6.3 1.1e-10 40.7 4.4 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGO22023.1 - 4.3e-08 31.9 0.2 0.00064 18.2 0.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein AMP-binding PF00501.23 EGO22024.1 - 1.3e-34 119.3 0.0 1.8e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EGO22024.1 - 5.9e-20 72.4 0.0 9.3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGO22024.1 - 4.2e-10 39.8 0.0 8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding_C PF13193.1 EGO22024.1 - 5.3e-10 40.1 0.2 1.3e-09 38.8 0.0 1.8 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EGO22024.1 - 4.5e-09 36.4 0.2 1.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EGO22024.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGO22024.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EGO22024.1 - 0.051 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.8 EGO22024.1 - 0.069 12.5 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EGO22024.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO22024.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acyl_transf_1 PF00698.16 EGO22026.1 - 4.9e-09 35.9 0.0 5.3e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DUF2945 PF11160.3 EGO22029.1 - 0.13 12.0 0.0 1.4 8.7 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2945) COX14 PF14880.1 EGO22030.1 - 0.81 9.3 4.9 0.62 9.7 0.1 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Synaptobrevin PF00957.16 EGO22030.1 - 7.7 6.2 6.2 3.5 7.2 0.4 2.4 2 0 0 2 2 2 0 Synaptobrevin RNase_PH_C PF03725.10 EGO22031.1 - 0.014 15.2 0.1 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 3' exoribonuclease family, domain 2 Myb_DNA-bind_5 PF13873.1 EGO22031.1 - 0.083 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TfoX_C PF04994.8 EGO22031.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 TfoX C-terminal domain ADH_N PF08240.7 EGO22032.1 - 7.9e-26 89.9 1.4 1.2e-25 89.3 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO22032.1 - 2.2e-23 82.2 0.4 3.9e-23 81.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3354 PF11834.3 EGO22033.1 - 0.21 11.2 0.3 0.21 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) DUF3614 PF12267.3 EGO22033.1 - 0.35 11.1 2.4 0.39 10.9 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Brix PF04427.13 EGO22034.1 - 9e-28 97.2 0.0 1.2e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain UMP1 PF05348.6 EGO22035.1 - 0.042 13.8 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 DUF4512 PF14975.1 EGO22039.1 - 0.077 13.8 0.4 0.098 13.4 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) HTH_30 PF13556.1 EGO22042.1 - 0.029 13.9 0.5 0.056 13.0 0.1 1.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Ibs_toxin PF13956.1 EGO22042.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Yae1_N PF09811.4 EGO22044.1 - 0.0016 17.8 1.2 0.0026 17.2 0.8 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PEARLI-4 PF05278.7 EGO22044.1 - 0.15 11.4 4.9 0.36 10.1 3.4 1.6 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) AAA_13 PF13166.1 EGO22044.1 - 0.25 9.7 7.7 0.34 9.3 5.3 1.1 1 0 0 1 1 1 0 AAA domain RWD PF05773.17 EGO22045.1 - 1.2e-07 31.5 0.1 2.5e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 RWD domain Sds3 PF08598.6 EGO22045.1 - 0.013 15.0 0.2 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Sds3-like SUV3_C PF12513.3 EGO22045.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Pkinase PF00069.20 EGO22046.1 - 7.1e-08 31.9 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO22046.1 - 3.9e-05 23.5 0.1 8.4e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO22046.1 - 0.0065 15.5 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO22046.1 - 0.024 13.9 0.3 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family WaaY PF06176.6 EGO22046.1 - 0.028 13.6 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) NDK PF00334.14 EGO22047.1 - 8e-55 184.3 0.0 9.1e-55 184.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EGO22047.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ GSH-S_N PF02951.9 EGO22050.1 - 0.038 13.7 0.1 0.054 13.2 0.1 1.3 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Takusan PF04822.8 EGO22050.1 - 0.1 12.3 3.3 0.13 12.0 1.4 1.8 2 0 0 2 2 2 0 Takusan I_LWEQ PF01608.12 EGO22050.1 - 0.11 12.4 1.0 0.14 12.0 0.7 1.1 1 0 0 1 1 1 0 I/LWEQ domain Aconitase PF00330.15 EGO22052.1 - 1e-157 525.3 0.1 8.7e-157 522.3 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO22052.1 - 1.8e-35 121.8 0.0 3.3e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EGO22052.1 - 0.1 11.1 0.0 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MutS_V PF00488.16 EGO22055.1 - 6e-83 277.8 0.5 7.6e-82 274.2 0.0 2.5 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.13 EGO22055.1 - 8.1e-39 133.5 0.7 1.4e-38 132.7 0.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGO22055.1 - 3.6e-22 78.5 0.0 1e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGO22055.1 - 4.1e-12 46.3 0.0 1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EGO22055.1 - 0.015 15.6 0.0 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO22055.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGO22055.1 - 0.067 13.4 0.1 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EGO22055.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain MutS_IV PF05190.13 EGO22055.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV Pkinase PF00069.20 EGO22056.1 - 1.1e-75 254.1 0.0 1.2e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22056.1 - 4.4e-40 137.3 0.0 5.5e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO22056.1 - 0.00031 19.7 0.0 0.0014 17.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO22056.1 - 0.0023 17.0 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO22056.1 - 0.0096 15.6 0.0 0.034 13.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO22056.1 - 0.023 14.2 0.4 0.045 13.3 0.2 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2962 PF11176.3 EGO22057.1 - 2e-33 115.1 2.0 2.5e-33 114.8 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Death PF00531.17 EGO22057.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Death domain MOZART1 PF12554.3 EGO22058.1 - 3.8e-25 87.0 0.3 4.6e-25 86.8 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Acetyltransf_1 PF00583.19 EGO22059.1 - 3.9e-12 46.0 0.0 6.8e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO22059.1 - 1.9e-08 33.9 0.0 3.2e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGO22059.1 - 9e-08 32.3 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO22059.1 - 8.8e-07 29.0 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO22059.1 - 0.00011 22.2 0.0 0.0011 19.1 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO22059.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO22059.1 - 0.0031 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGO22059.1 - 0.0045 16.8 0.0 0.021 14.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO22059.1 - 0.073 13.0 0.0 0.88 9.5 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGO22059.1 - 0.13 12.0 0.3 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase FAD_binding_3 PF01494.14 EGO22060.1 - 3.3e-61 207.3 0.0 5.4e-61 206.6 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO22060.1 - 0.00017 21.5 0.2 0.00046 20.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO22060.1 - 0.00025 20.0 0.2 0.00044 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO22060.1 - 0.00043 18.8 0.1 0.00084 17.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EGO22060.1 - 0.0014 17.8 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EGO22060.1 - 0.0016 18.5 0.1 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO22060.1 - 0.0018 18.1 0.0 0.005 16.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO22060.1 - 0.0038 15.9 0.0 0.0058 15.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_7 PF13241.1 EGO22060.1 - 0.038 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EGO22060.1 - 0.04 14.3 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO22060.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EGO22060.1 - 0.12 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4066 PF13278.1 EGO22061.1 - 1e-17 63.9 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGO22061.1 - 3e-13 49.4 0.0 3.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGO22062.1 - 3.2e-16 59.0 0.1 8.8e-16 57.6 0.0 1.7 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGO22062.1 - 1.4e-12 47.2 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGO22062.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I FAD_binding_3 PF01494.14 EGO22063.1 - 2.4e-67 227.5 0.0 4e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO22063.1 - 0.00011 22.1 0.0 0.00046 20.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO22063.1 - 0.00059 19.0 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO22063.1 - 0.00071 19.5 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO22063.1 - 0.00077 18.4 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO22063.1 - 0.0011 17.5 0.0 0.0024 16.4 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EGO22063.1 - 0.0017 17.3 0.0 0.0039 16.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO22063.1 - 0.0047 16.7 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGO22063.1 - 0.0053 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EGO22063.1 - 0.018 15.0 0.4 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.2 EGO22063.1 - 0.022 13.8 0.0 0.052 12.6 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EGO22063.1 - 0.022 13.6 0.1 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EGO22063.1 - 0.079 13.3 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase hDGE_amylase PF14701.1 EGO22066.1 - 3.2e-156 520.4 0.0 4.3e-156 520.0 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGO22066.1 - 1.2e-116 389.5 0.0 1.7e-116 389.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGO22066.1 - 1.9e-79 266.4 0.0 2.7e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EGO22066.1 - 1.4e-18 66.4 0.0 3.6e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EGO22066.1 - 0.004 16.5 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain SCA7 PF08313.7 EGO22073.1 - 1.1e-28 98.6 0.2 1.1e-28 98.6 0.1 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain FAD_binding_3 PF01494.14 EGO22075.1 - 5.9e-21 74.9 0.0 1.9e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO22075.1 - 3.5e-12 45.9 0.6 3.7e-09 35.9 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO22075.1 - 2e-09 37.3 0.1 9.5e-09 35.1 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO22075.1 - 2.5e-07 29.9 0.0 4.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO22075.1 - 6e-07 28.2 0.0 8.8e-07 27.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EGO22075.1 - 6.8e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO22075.1 - 8.7e-05 22.4 0.1 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGO22075.1 - 0.00011 21.4 0.0 0.0026 16.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EGO22075.1 - 0.00013 20.9 0.2 0.041 12.7 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGO22075.1 - 0.00053 20.1 0.1 0.0018 18.4 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO22075.1 - 0.00097 19.5 0.2 0.0028 18.0 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO22075.1 - 0.0033 16.5 0.0 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO22075.1 - 0.012 14.4 0.2 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGO22075.1 - 0.023 13.3 0.1 0.09 11.3 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 EGO22075.1 - 0.041 13.3 0.1 0.087 12.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 EGO22075.1 - 0.049 12.7 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_9 PF13454.1 EGO22075.1 - 0.093 12.5 1.3 0.34 10.6 0.2 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 EGO22077.1 - 6.9e-17 61.1 0.1 1.7e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpc4 PF05132.9 EGO22078.1 - 5.8e-21 74.8 0.8 5.8e-21 74.8 0.5 2.4 2 2 0 2 2 2 1 RNA polymerase III RPC4 Pribosyltran PF00156.22 EGO22079.1 - 6.1e-09 35.6 0.0 9.6e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.22 EGO22080.1 - 1.3e-70 233.1 3.0 1.7e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4499 PF14934.1 EGO22080.1 - 0.0071 16.2 0.2 0.026 14.4 0.0 2.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4499) KduI PF04962.7 EGO22080.1 - 0.031 13.3 0.0 0.12 11.4 0.0 1.7 1 1 1 2 2 2 0 KduI/IolB family Alg14 PF08660.6 EGO22080.1 - 0.036 14.0 0.2 0.28 11.1 0.1 2.0 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like p450 PF00067.17 EGO22082.1 - 6.9e-67 225.9 0.0 8e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4219 PF13961.1 EGO22083.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Helicase_C PF00271.26 EGO22094.1 - 2.4e-13 49.7 0.0 4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VanY PF02557.12 EGO22095.1 - 0.079 12.8 1.0 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF4219 PF13961.1 EGO22096.1 - 0.11 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) PepSY_TM_1 PF13172.1 EGO22097.1 - 5.2 6.9 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO22098.1 - 2.8e-08 33.2 1.1 4e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO22098.1 - 0.077 12.6 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO22098.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Ank_2 PF12796.2 EGO22099.1 - 6.9e-46 154.5 2.5 2e-14 53.6 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO22099.1 - 2.6e-40 136.0 9.1 4.5e-11 42.9 0.0 7.8 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 EGO22099.1 - 2.7e-34 115.2 11.7 7.7e-05 22.3 0.0 9.8 9 1 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 EGO22099.1 - 3.4e-30 101.0 5.5 0.0017 18.4 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EGO22099.1 - 5.6e-30 102.6 10.7 1.1e-08 35.0 0.0 6.8 5 2 2 7 7 7 6 Ankyrin repeats (many copies) BenE PF03594.8 EGO22100.1 - 0.11 10.9 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Benzoate membrane transport protein p450 PF00067.17 EGO22102.1 - 2.2e-10 39.6 0.0 3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO22103.1 - 2.8e-60 204.1 0.0 7.4e-60 202.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TRAUB PF08164.7 EGO22105.1 - 3.6e-28 97.4 1.8 4.5e-28 97.1 0.1 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EGO22105.1 - 1.1e-22 80.5 0.4 1.1e-22 80.5 0.3 3.0 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor PX PF00787.19 EGO22106.1 - 1.4e-21 76.3 0.3 7.1e-21 74.1 0.0 2.3 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGO22106.1 - 1.6e-06 27.5 8.6 0.0051 16.1 1.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EGO22106.1 - 0.002 17.6 0.7 0.002 17.6 0.5 1.7 2 0 0 2 2 2 1 BAR domain DUF4391 PF14335.1 EGO22106.1 - 0.019 14.3 0.8 0.052 12.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) FAM92 PF06730.6 EGO22106.1 - 0.068 12.4 0.2 0.068 12.4 0.1 2.0 3 0 0 3 3 3 0 FAM92 protein DUF2924 PF11149.3 EGO22106.1 - 0.09 12.8 0.4 0.23 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) UAA PF08449.6 EGO22107.1 - 5.9e-15 54.9 18.8 8.2e-15 54.4 13.0 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGO22107.1 - 4.4e-10 39.4 5.0 4.4e-10 39.4 3.5 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGO22107.1 - 0.0039 17.2 5.5 0.0039 17.2 3.8 2.2 2 0 0 2 2 2 1 EamA-like transporter family CPSase_L_D2 PF02786.12 EGO22108.1 - 2.6e-81 271.9 0.1 4.8e-81 271.0 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EGO22108.1 - 1.3e-66 223.8 0.0 2.6e-66 222.8 0.0 1.6 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EGO22108.1 - 1.1e-36 125.2 0.0 3.3e-36 123.7 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 EGO22108.1 - 7.4e-30 104.3 0.0 1.5e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 EGO22108.1 - 3.4e-29 100.9 0.0 1.1e-28 99.3 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EGO22108.1 - 7.2e-20 71.4 0.1 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGO22108.1 - 2.3e-18 65.6 4.4 8e-18 63.8 2.4 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGO22108.1 - 1.5e-17 63.3 0.0 9.5e-17 60.7 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EGO22108.1 - 3.8e-12 45.6 5.6 1.2e-07 31.2 0.0 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EGO22108.1 - 9.5e-12 44.7 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGO22108.1 - 1.2e-08 34.4 0.0 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EGO22108.1 - 2.5e-08 33.6 2.2 0.00051 19.4 0.1 2.6 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EGO22108.1 - 4.1e-06 27.0 0.5 0.035 14.4 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EGO22108.1 - 1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.14 EGO22108.1 - 0.00047 19.8 3.0 0.0011 18.6 0.4 2.7 2 1 1 3 3 3 1 Glycine cleavage H-protein RimK PF08443.6 EGO22108.1 - 0.00049 19.6 0.0 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.6 EGO22108.1 - 0.001 18.3 0.8 0.0043 16.2 0.2 2.0 2 0 0 2 2 2 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 EGO22108.1 - 0.003 17.2 1.0 0.041 13.5 0.5 2.6 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 EGO22108.1 - 0.0095 15.1 0.5 0.26 10.3 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EGO22108.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 EGO22108.1 - 0.065 12.9 0.2 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) PNPase PF03726.9 EGO22108.1 - 0.12 12.6 0.2 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NMO PF03060.10 EGO22109.1 - 2e-55 188.2 0.2 9.1e-55 186.1 0.1 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EGO22109.1 - 0.0006 18.7 0.7 0.0013 17.6 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGO22109.1 - 0.0016 17.4 0.0 0.36 9.6 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain VRR_NUC PF08774.6 EGO22109.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 VRR-NUC domain LSM PF01423.17 EGO22110.1 - 1.1e-15 56.9 0.0 1.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain RhoGAP PF00620.22 EGO22115.1 - 1.3e-37 128.7 0.0 2.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EGO22115.1 - 1.8e-12 47.3 0.0 4.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGO22115.1 - 2.5e-07 30.9 0.0 7.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 EGO22115.1 - 1.1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PX domain PH_8 PF15409.1 EGO22115.1 - 0.0014 18.6 0.1 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain Spexin PF15171.1 EGO22116.1 - 0.025 14.5 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin SDH_alpha PF03313.10 EGO22117.1 - 2.7e-90 302.2 0.9 3.7e-90 301.7 0.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EGO22117.1 - 6.3e-10 39.3 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Cyclin_N PF00134.18 EGO22118.1 - 9.5e-12 44.5 0.0 1e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain AAA_33 PF13671.1 EGO22119.1 - 1.6e-20 73.4 0.0 9.7e-20 70.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGO22119.1 - 2.9e-05 23.4 0.0 0.18 11.0 0.0 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGO22119.1 - 5.7e-05 23.9 0.0 0.00012 22.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO22119.1 - 8.9e-05 22.8 0.0 0.0077 16.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO22119.1 - 0.00012 21.2 0.0 0.032 13.3 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin tRNA_lig_kinase PF08303.6 EGO22119.1 - 0.004 17.0 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain 6PF2K PF01591.13 EGO22119.1 - 0.029 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.7 EGO22119.1 - 0.062 12.9 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 EGO22119.1 - 0.098 12.3 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase TPR_11 PF13414.1 EGO22120.1 - 4.8e-21 74.1 0.5 2.6e-11 43.0 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGO22120.1 - 1.9e-14 52.3 1.6 1.6e-06 27.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO22120.1 - 6e-14 50.9 0.6 1.8e-06 27.3 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO22120.1 - 1.8e-13 50.7 0.6 5.4e-07 30.1 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO22120.1 - 3.3e-13 49.3 2.7 6.5e-06 26.0 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO22120.1 - 3.5e-13 48.6 0.5 0.0026 17.8 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO22120.1 - 2.3e-10 40.6 0.6 0.00063 20.0 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO22120.1 - 1.8e-08 34.2 3.4 0.00082 19.8 0.0 4.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO22120.1 - 3.2e-07 29.6 0.6 0.022 14.5 0.0 4.3 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22120.1 - 4.2e-07 29.2 2.8 0.0062 16.2 0.0 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGO22120.1 - 4e-06 26.5 2.7 0.43 10.5 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO22120.1 - 0.00016 21.7 0.3 0.063 13.4 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGO22120.1 - 0.00022 21.4 1.1 0.44 11.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EGO22120.1 - 0.00075 19.3 1.8 1.4 8.8 0.1 3.2 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain Apc5 PF12862.2 EGO22120.1 - 0.0047 16.7 1.3 0.0076 16.0 0.1 1.8 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 EGO22120.1 - 0.0072 16.4 2.7 0.14 12.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO22120.1 - 0.0073 16.1 0.0 4.5 7.1 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 EGO22120.1 - 0.0094 15.7 1.5 3 7.6 0.1 2.7 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 EGO22120.1 - 0.035 14.5 2.9 0.96 10.0 0.0 3.9 4 1 1 5 5 4 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 EGO22120.1 - 0.23 11.2 1.3 6.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Exonuclease VII small subunit Tim17 PF02466.14 EGO22121.1 - 6.7e-25 87.5 6.3 8.5e-25 87.2 4.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Velvet PF11754.3 EGO22122.1 - 3.4e-27 95.3 0.0 5.9e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Cytochrom_C1 PF02167.10 EGO22124.1 - 5e-85 284.6 0.0 6e-85 284.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EGO22124.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EGO22124.1 - 0.01 16.6 0.2 0.025 15.3 0.1 1.8 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.11 EGO22125.1 - 7.4e-59 198.7 1.4 1.1e-58 198.2 0.9 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGO22125.1 - 5.6e-09 35.8 1.2 8e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 tRNA_int_endo PF01974.12 EGO22127.1 - 3.6e-20 71.5 0.0 6.9e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGO22127.1 - 1.8e-05 24.1 0.0 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 EGO22128.1 - 7e-18 63.7 6.6 1e-05 25.2 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat Aminotran_5 PF00266.14 EGO22129.1 - 4.6e-31 107.8 0.0 6.1e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EGO22129.1 - 0.00074 19.3 0.6 0.013 15.3 0.2 2.4 2 0 0 2 2 2 1 B12 binding domain adh_short PF00106.20 EGO22129.1 - 0.049 13.5 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NIR_SIR PF01077.17 EGO22130.1 - 6.9e-48 161.9 0.0 3e-43 146.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGO22130.1 - 2e-31 107.3 0.0 9.3e-16 57.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EGO22130.1 - 2e-28 99.1 0.0 3.8e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EGO22130.1 - 0.051 13.0 0.1 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 EGO22130.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Prenyltrans PF00432.16 EGO22131.1 - 3.2e-37 125.7 2.3 4.8e-10 38.8 0.2 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EGO22131.1 - 2.8e-28 98.1 0.6 7.8e-12 45.1 0.1 6.3 3 3 3 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGO22131.1 - 4.4e-26 91.5 1.4 5.9e-17 62.1 0.0 4.7 3 2 0 3 3 3 3 Prenyltransferase-like Pec_lyase PF09492.5 EGO22131.1 - 2.5e-10 39.9 0.1 0.19 10.8 0.0 5.2 1 1 4 5 5 5 4 Pectic acid lyase A2M_comp PF07678.9 EGO22131.1 - 0.00032 20.0 0.1 0.14 11.3 0.0 3.7 3 1 1 4 4 4 1 A-macroglobulin complement component DUF957 PF06117.6 EGO22132.1 - 0.43 10.1 0.1 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) DUF3340 PF11818.3 EGO22133.1 - 0.015 15.2 4.4 0.017 15.1 3.0 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF3523 PF12037.3 EGO22133.1 - 0.6 9.0 11.1 0.71 8.7 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) PV-1 PF06637.6 EGO22133.1 - 1.3 7.4 6.2 1.5 7.3 4.3 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CCP_MauG PF03150.9 EGO22134.1 - 1 9.6 4.3 5.9 7.1 1.2 2.2 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Actin PF00022.14 EGO22135.1 - 3.5e-41 140.9 0.0 6.9e-41 139.9 0.0 1.4 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.21 EGO22136.1 - 1.6e-22 78.7 0.0 1.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_3 PF13606.1 EGO22137.1 - 0.0095 16.0 0.0 0.064 13.5 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EGO22137.1 - 0.045 14.0 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) PMM PF03332.8 EGO22138.1 - 1.4e-105 351.7 0.4 1.6e-105 351.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGO22138.1 - 0.0018 17.9 0.0 0.036 13.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGO22138.1 - 0.02 14.2 0.0 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DNA_pol_B PF00136.16 EGO22139.1 - 2e-143 478.5 0.5 3e-143 478.0 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGO22139.1 - 3.9e-86 288.8 0.0 7.8e-86 287.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGO22139.1 - 3.9e-23 81.2 7.3 1.1e-22 79.8 5.1 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EGO22139.1 - 0.0029 17.4 0.1 0.0079 16.0 0.1 1.9 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EGO22139.1 - 0.0089 14.7 2.4 0.045 12.4 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 EGO22139.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Cnd2 PF05786.9 EGO22140.1 - 6.2e-153 511.0 8.0 4.6e-151 504.8 5.5 2.1 1 1 0 1 1 1 1 Condensin complex subunit 2 5_nucleotid_C PF02872.13 EGO22141.1 - 0.057 13.4 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain zf-CHCC PF10276.4 EGO22143.1 - 0.18 11.6 0.5 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger domain DEAD PF00270.24 EGO22144.1 - 0.033 13.6 0.0 0.22 11.0 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ING PF12998.2 EGO22145.1 - 0.039 14.2 0.5 0.11 12.8 0.1 1.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Biopterin_H PF00351.16 EGO22146.1 - 0.0038 16.0 0.0 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Atx10homo_assoc PF09759.4 EGO22150.1 - 1.8e-22 78.9 0.1 9.9e-22 76.6 0.0 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 EGO22150.1 - 0.0047 17.1 0.0 0.054 13.7 0.0 2.6 3 1 0 3 3 3 1 HEAT repeats Arm_2 PF04826.8 EGO22150.1 - 0.11 11.6 0.1 0.29 10.2 0.0 1.7 1 0 0 1 1 1 0 Armadillo-like BRAP2 PF07576.7 EGO22151.1 - 1.2e-22 79.5 0.0 2.5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EGO22151.1 - 1.7e-19 69.6 4.5 3.8e-19 68.5 3.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EGO22151.1 - 9.8e-09 34.9 10.1 9.8e-09 34.9 7.0 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO22151.1 - 1.2e-05 24.8 7.7 2.8e-05 23.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO22151.1 - 5.4e-05 23.2 3.9 0.00014 21.9 2.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO22151.1 - 0.00018 21.1 7.3 0.00018 21.1 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO22151.1 - 0.00035 20.2 6.9 0.00035 20.2 4.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO22151.1 - 0.00043 20.2 9.6 0.00043 20.2 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO22151.1 - 0.0067 16.2 3.5 0.015 15.1 2.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGO22151.1 - 0.12 11.9 6.0 0.31 10.6 4.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGO22151.1 - 0.13 12.0 4.8 0.15 11.8 1.8 2.2 1 1 1 2 2 2 0 RING-type zinc-finger V_ATPase_I PF01496.14 EGO22151.1 - 0.53 8.0 11.1 0.72 7.6 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HR1 PF02185.11 EGO22151.1 - 0.57 9.9 15.6 0.08 12.6 4.9 2.4 2 0 0 2 2 2 0 Hr1 repeat Lipoprotein_X PF03305.8 EGO22151.1 - 0.91 8.8 6.2 1.5 8.1 4.3 1.3 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Laminin_II PF06009.7 EGO22151.1 - 1.1 8.9 9.9 0.19 11.5 2.9 2.1 2 0 0 2 2 2 0 Laminin Domain II TerY-C PF15616.1 EGO22151.1 - 2.6 7.9 14.4 0.6 10.0 3.2 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain FlaC_arch PF05377.6 EGO22151.1 - 4.3 7.2 5.8 6.3 6.7 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EGO22151.1 - 4.4 7.4 10.5 2.5 8.2 1.9 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_S49 PF01343.13 EGO22151.1 - 7.1 6.3 7.4 15 5.3 5.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 Flavi_NS2B PF01002.14 EGO22152.1 - 0.00076 19.0 0.8 0.0026 17.3 0.6 1.9 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2B PIG-P PF08510.7 EGO22152.1 - 0.009 15.6 2.8 0.009 15.6 1.9 2.7 3 1 0 3 3 3 1 PIG-P ParA PF10609.4 EGO22155.1 - 1.6e-36 124.0 0.0 2.8e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGO22155.1 - 5.1e-13 48.8 0.0 7.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EGO22155.1 - 4.7e-06 25.8 0.8 0.003 16.6 0.1 2.7 2 1 0 2 2 2 2 Anion-transporting ATPase AAA_25 PF13481.1 EGO22155.1 - 0.00041 19.7 0.0 0.00064 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EGO22155.1 - 0.001 19.0 0.0 0.0036 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO22155.1 - 0.014 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YhjQ PF06564.7 EGO22155.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein AAA_26 PF13500.1 EGO22155.1 - 0.04 13.5 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 EGO22155.1 - 0.049 12.8 0.0 0.9 8.6 0.0 2.4 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YjeF_N PF03853.10 EGO22155.1 - 0.065 12.8 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus VirE PF05272.6 EGO22155.1 - 0.11 11.9 0.1 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E MipZ PF09140.6 EGO22155.1 - 0.12 11.3 0.0 0.63 9.0 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ AAA_29 PF13555.1 EGO22155.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 EGO22156.1 - 8.3e-12 44.7 0.0 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22156.1 - 4.6e-05 22.6 0.0 5.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Symplekin_C PF12295.3 EGO22157.1 - 6.9e-58 195.5 0.3 2.2e-57 193.9 0.2 1.9 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EGO22157.1 - 3.1e-49 167.5 0.1 7.1e-49 166.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CRM1_C PF08767.6 EGO22157.1 - 0.044 12.6 0.0 5.1 5.9 0.0 2.6 2 0 0 2 2 2 0 CRM1 C terminal HEAT PF02985.17 EGO22157.1 - 0.047 13.7 0.2 15 6.0 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat PI-PLC-Y PF00387.14 EGO22157.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Fungal_trans PF04082.13 EGO22158.1 - 1.1e-16 60.4 3.4 2.3e-16 59.4 2.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO22158.1 - 1.1e-09 38.0 11.1 1.9e-09 37.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EGO22159.1 - 9.5e-28 96.4 13.3 1.1e-27 96.1 9.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EGO22160.1 - 4.9e-32 109.3 0.2 7.5e-32 108.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EGO22160.1 - 0.025 14.6 0.1 0.51 10.3 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain FliH PF02108.11 EGO22160.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH RhoGAP PF00620.22 EGO22161.1 - 2e-34 118.4 0.0 3.9e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EGO22161.1 - 4.5e-26 90.6 37.5 3.3e-11 43.0 5.1 4.7 5 0 0 5 5 5 4 LIM domain DUF914 PF06027.7 EGO22163.1 - 3.9e-103 344.8 12.5 4.7e-103 344.5 8.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGO22163.1 - 5.2e-05 22.3 16.3 7.3e-05 21.8 11.3 1.1 1 0 0 1 1 1 1 UAA transporter family CHCH PF06747.8 EGO22164.1 - 5.5e-06 26.1 5.7 7.7e-06 25.6 3.9 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EGO22164.1 - 1.3e-05 25.2 2.3 1.8e-05 24.7 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 EGO22164.1 - 0.0041 16.9 2.0 0.041 13.7 1.4 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 EGO22164.1 - 0.027 14.4 3.1 0.047 13.7 1.9 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PSP94 PF05825.6 EGO22164.1 - 0.028 14.6 0.8 0.034 14.4 0.6 1.1 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) RRM_1 PF00076.17 EGO22165.1 - 5.7e-31 105.9 2.0 4.6e-15 54.9 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO22165.1 - 9.4e-23 79.9 0.1 7.4e-08 32.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO22165.1 - 5.9e-15 54.8 0.2 0.00032 20.4 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 EGO22165.1 - 0.1 12.5 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family Fis1_TPR_C PF14853.1 EGO22166.1 - 2.3e-22 78.6 0.1 3.7e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGO22166.1 - 3.2e-16 58.3 0.0 5.1e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGO22166.1 - 0.00025 20.7 0.1 0.00054 19.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO22166.1 - 0.0071 15.9 0.3 0.013 15.1 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO22166.1 - 0.014 15.7 0.2 0.026 14.8 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO22166.1 - 0.042 13.9 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGO22166.1 - 0.057 13.9 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M50B PF13398.1 EGO22167.1 - 2.4e-40 138.0 18.3 2.9e-40 137.8 12.7 1.0 1 0 0 1 1 1 1 Peptidase M50B-like DUF3366 PF11846.3 EGO22167.1 - 0.054 13.3 0.1 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) AmiS_UreI PF02293.10 EGO22167.1 - 0.57 9.8 10.5 2.1 7.9 7.3 2.1 1 1 0 1 1 1 0 AmiS/UreI family transporter Histone PF00125.19 EGO22168.1 - 2.6e-26 91.5 0.0 3.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO22168.1 - 1.7e-06 27.9 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FCH PF00611.18 EGO22169.1 - 9.6e-11 41.7 0.0 2.8e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EGO22169.1 - 2.4e-07 30.4 0.0 7.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 EGO22169.1 - 9.1e-07 28.5 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Vpu PF00558.14 EGO22169.1 - 0.37 10.3 1.7 1.1 8.8 1.2 1.7 1 0 0 1 1 1 0 Vpu protein Ribonucleas_3_3 PF14622.1 EGO22170.1 - 1e-08 35.2 0.0 3.6e-08 33.4 0.0 1.8 1 1 1 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 EGO22170.1 - 1.9e-07 31.5 0.0 3.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EGO22170.1 - 0.00012 22.4 0.0 0.00018 21.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Peptidase_M20 PF01546.23 EGO22171.1 - 1.3e-25 90.0 0.0 1.9e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO22171.1 - 2.8e-12 46.3 0.0 5.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGO22171.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Turandot PF07240.6 EGO22174.1 - 0.0055 16.1 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Stress-inducible humoral factor Turandot Snf7 PF03357.16 EGO22174.1 - 0.018 14.4 0.3 0.022 14.1 0.2 1.3 1 0 0 1 1 1 0 Snf7 DUF4653 PF15546.1 EGO22174.1 - 0.019 14.2 0.4 0.02 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) SAS4 PF15460.1 EGO22174.1 - 0.087 12.7 1.6 0.2 11.5 1.0 1.7 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Nsp1_C PF05064.8 EGO22174.1 - 0.088 12.4 0.4 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Peptidase_M20 PF01546.23 EGO22175.1 - 4.2e-17 62.2 1.9 8.7e-17 61.2 1.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO22175.1 - 5.5e-13 48.6 0.0 1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-H2C2_2 PF13465.1 EGO22177.1 - 2.6e-27 93.7 43.9 2.2e-07 30.8 0.2 7.9 8 1 0 8 8 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 EGO22177.1 - 4.3e-26 89.6 36.1 1.6e-05 24.9 0.0 7.9 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO22177.1 - 3.2e-16 58.3 36.9 0.00097 19.3 0.9 7.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO22177.1 - 3.7e-08 33.0 22.7 0.0094 15.8 0.4 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO22177.1 - 2.7e-06 27.3 7.9 0.05 13.7 0.3 5.2 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGO22177.1 - 1.7e-05 24.3 4.8 1.9 8.2 0.0 5.3 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EGO22177.1 - 0.0004 20.4 18.0 0.33 11.0 5.1 4.8 3 2 2 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EGO22177.1 - 0.00054 20.0 16.8 0.079 13.0 0.6 4.8 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EGO22177.1 - 0.0087 16.2 2.0 0.0087 16.2 1.4 6.1 6 1 0 6 6 5 1 C2H2-type zinc-finger domain PyrI_C PF02748.10 EGO22177.1 - 0.056 12.8 0.6 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.2 EGO22177.1 - 0.093 12.9 0.8 0.093 12.9 0.5 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 EGO22177.1 - 0.098 12.1 10.7 0.056 12.9 0.8 3.2 3 0 0 3 3 3 0 InsA N-terminal domain BIR PF00653.16 EGO22177.1 - 1.2 9.6 7.6 15 6.0 2.0 2.9 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain CTP_transf_2 PF01467.21 EGO22178.1 - 2.3e-09 37.4 0.0 4.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Lactamase_B PF00753.22 EGO22179.1 - 2.7e-08 33.6 0.2 6.7e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO22179.1 - 0.00079 19.0 0.3 0.0021 17.6 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO22180.1 - 2.4e-08 33.8 0.4 3.2e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO22180.1 - 4.9e-05 22.9 0.2 0.00013 21.5 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO22180.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO22181.1 - 5.6e-06 26.1 0.3 8.2e-06 25.6 0.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO22181.1 - 0.005 16.4 0.3 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RHS PF03527.9 EGO22182.1 - 0.085 12.6 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 RHS protein zf-RING_2 PF13639.1 EGO22183.1 - 3.3e-08 33.2 5.7 3.3e-08 33.2 3.9 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGO22183.1 - 3.6e-08 32.9 5.2 3.6e-08 32.9 3.6 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO22183.1 - 4.6e-08 32.6 5.0 4.6e-08 32.6 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO22183.1 - 2e-07 30.6 5.5 2e-07 30.6 3.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO22183.1 - 9e-07 28.8 7.2 9e-07 28.8 5.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO22183.1 - 0.0052 16.4 3.3 0.0082 15.8 1.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-CCCH PF00642.19 EGO22183.1 - 0.023 14.3 33.7 0.032 13.9 3.3 4.3 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 PF12678.2 EGO22183.1 - 0.78 9.8 12.4 1.5 8.9 7.3 2.6 1 1 1 2 2 2 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGO22183.1 - 3 7.7 16.6 0.044 13.6 4.9 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SAGA-Tad1 PF12767.2 EGO22184.1 - 3.5e-33 115.3 0.0 1.3e-32 113.5 0.0 1.8 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EGO22184.1 - 0.047 12.9 0.2 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GFO_IDH_MocA PF01408.17 EGO22185.1 - 4.3e-20 72.4 0.0 6.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OHCU_decarbox PF09349.5 EGO22186.1 - 4.4e-31 108.3 0.0 5.2e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.26 EGO22187.1 - 7e-20 70.5 0.7 7e-20 70.5 0.5 2.2 2 1 0 2 2 2 1 DnaJ domain DUF217 PF02697.9 EGO22187.1 - 0.34 11.2 6.8 0.94 9.7 0.6 3.4 2 1 2 4 4 4 0 Uncharacterized ACR, COG1753 Ndc1_Nup PF09531.5 EGO22187.1 - 3.9 5.7 6.1 4.5 5.5 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Abhydrolase_6 PF12697.2 EGO22188.1 - 3.3e-23 82.7 0.0 4.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO22188.1 - 2.7e-11 43.4 0.0 2.9e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO22188.1 - 1.3e-08 34.6 0.0 2.9e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGO22188.1 - 0.00019 20.9 0.0 0.00049 19.5 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EGO22188.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EGO22188.1 - 0.0018 16.7 0.0 0.004 15.6 0.0 1.5 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.16 EGO22188.1 - 0.054 12.6 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.15 EGO22188.1 - 0.11 12.7 0.1 0.34 11.1 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain Torsin PF06309.6 EGO22188.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Torsin Pkinase PF00069.20 EGO22189.1 - 6.5e-72 241.7 0.0 7.6e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22189.1 - 1.3e-31 109.6 0.0 3.2e-31 108.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGO22189.1 - 0.029 14.1 0.1 0.066 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO22189.1 - 0.043 12.7 0.1 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 EGO22189.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NADH-u_ox-rdase PF10785.4 EGO22191.1 - 7e-33 112.7 0.7 1e-32 112.2 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EGO22191.1 - 5.7e-18 64.4 0.0 8.2e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF1459 PF07312.6 EGO22191.1 - 0.08 12.8 0.3 0.7 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) WD40 PF00400.27 EGO22192.1 - 1.2e-15 56.6 10.8 0.00022 20.9 0.5 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO22192.1 - 0.0063 15.3 0.3 0.044 12.5 0.2 2.3 1 1 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.3 EGO22192.1 - 0.014 13.5 0.0 0.027 12.6 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Hira PF07569.6 EGO22192.1 - 0.022 13.9 0.1 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF1192 PF06698.6 EGO22192.1 - 0.031 14.0 0.0 0.088 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) WD40_alt PF14077.1 EGO22192.1 - 0.12 12.0 0.4 0.28 10.8 0.3 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif DivIVA PF05103.8 EGO22192.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 DivIVA protein DUF3639 PF12341.3 EGO22192.1 - 0.15 12.0 1.6 0.39 10.7 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) DnaJ PF00226.26 EGO22193.1 - 4.6e-21 74.3 0.1 6.8e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SH3_1 PF00018.23 EGO22194.1 - 7.5e-17 60.4 2.1 3e-07 29.7 0.1 3.1 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.12 EGO22194.1 - 1.1e-11 44.4 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGO22194.1 - 1.9e-11 43.9 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EGO22194.1 - 2.9e-11 42.7 2.8 6.5e-05 22.4 0.2 2.7 2 1 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EGO22194.1 - 5.7e-11 41.7 0.6 1.7e-07 30.6 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.18 EGO22194.1 - 2.9e-10 40.5 0.9 5.5e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.6 EGO22194.1 - 0.00092 19.3 4.2 0.12 12.6 0.3 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain DUF1319 PF07028.6 EGO22194.1 - 0.0049 17.0 0.1 0.0099 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Med9 PF07544.8 EGO22194.1 - 0.025 14.3 1.0 0.073 12.8 0.7 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NUDIX PF00293.23 EGO22195.1 - 2e-10 40.4 0.0 3.2e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.19 EGO22196.1 - 2.8e-41 141.5 30.0 5.3e-40 137.3 20.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO22196.1 - 5e-18 64.9 40.6 3.8e-10 38.9 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 EGO22196.1 - 0.0096 16.0 2.1 0.0096 16.0 1.5 4.1 3 2 1 4 4 4 2 Protein of unknown function, DUF606 PIG-Y PF15159.1 EGO22196.1 - 0.037 14.2 0.9 0.23 11.6 0.2 2.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SR-25 PF10500.4 EGO22199.1 - 0.0022 17.5 0.2 0.0025 17.3 0.1 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SIP PF04954.8 EGO22199.1 - 0.0065 16.8 0.1 0.0073 16.6 0.1 1.1 1 0 0 1 1 1 1 Siderophore-interacting protein DUF3983 PF13137.1 EGO22199.1 - 0.84 9.3 10.4 0.095 12.4 4.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) DEAD PF00270.24 EGO22202.1 - 3.8e-10 39.5 0.0 6.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO22202.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T4SS-DNA_transf PF02534.9 EGO22202.1 - 0.00034 19.3 0.1 0.00058 18.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF2956 PF11169.3 EGO22202.1 - 0.013 15.4 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Bin3 PF06859.7 EGO22202.1 - 0.034 14.1 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) ResIII PF04851.10 EGO22202.1 - 0.041 13.7 0.6 0.079 12.7 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit 2_5_RNA_ligase2 PF13563.1 EGO22203.1 - 0.059 13.0 0.2 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily BDHCT PF08072.6 EGO22204.1 - 0.079 13.0 0.2 0.59 10.2 0.1 2.2 2 0 0 2 2 2 0 BDHCT (NUC031) domain Myb_DNA-bind_3 PF12776.2 EGO22205.1 - 0.00045 20.7 1.1 0.0012 19.4 0.2 1.9 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO22205.1 - 0.0016 18.5 0.8 0.028 14.5 0.6 2.3 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.12 EGO22206.1 - 1.3e-06 28.4 2.6 3.8e-06 26.8 1.8 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_1 PF03184.14 EGO22207.1 - 4.8e-13 48.7 0.1 3.1e-12 46.1 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EGO22210.1 - 1.2e-05 24.5 0.0 1.2e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 DUF4279 PF14106.1 EGO22212.1 - 0.035 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Rota_NSP4 PF01452.11 EGO22212.1 - 0.075 12.3 0.0 0.089 12.1 0.0 1.0 1 0 0 1 1 1 0 Rotavirus non structural protein HrpB7 PF09486.5 EGO22212.1 - 0.08 12.8 1.0 0.099 12.5 0.7 1.0 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4515 PF14988.1 EGO22212.1 - 0.081 12.5 0.0 0.087 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) PQ-loop PF04193.9 EGO22214.1 - 6.5e-17 60.8 3.2 2.8e-11 42.7 0.8 2.7 2 0 0 2 2 2 2 PQ loop repeat EutH PF04346.7 EGO22214.1 - 0.0046 15.9 0.9 0.0097 14.8 0.6 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation protein, EutH Clathrin PF00637.15 EGO22215.1 - 1.4e-203 666.6 26.4 7.6e-32 109.8 0.3 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EGO22215.1 - 6.8e-33 110.7 2.4 0.00029 20.9 0.0 7.8 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 EGO22215.1 - 7.4e-29 99.4 0.2 2.7e-28 97.6 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EGO22215.1 - 7.4e-11 40.8 0.5 2.8e-10 39.0 0.1 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EGO22215.1 - 0.00076 18.3 8.8 0.19 10.4 0.1 4.4 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.23 EGO22215.1 - 0.0079 15.7 2.9 11 5.7 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO22215.1 - 0.012 15.4 2.7 20 5.3 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22215.1 - 0.026 14.3 3.7 27 4.8 0.1 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO22215.1 - 0.043 13.7 8.8 0.86 9.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 EGO22215.1 - 0.13 12.2 0.1 51 4.1 0.0 4.8 7 0 0 7 7 7 0 PPR repeat Ras PF00071.17 EGO22216.1 - 2e-50 170.3 0.0 2.4e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO22216.1 - 2.2e-15 57.1 0.0 3.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO22216.1 - 1.7e-06 27.4 0.0 2.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO22216.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO22216.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGO22216.1 - 0.019 14.1 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Skp1_POZ PF03931.10 EGO22216.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain ADH_zinc_N PF00107.21 EGO22217.1 - 3e-15 55.9 0.0 5.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO22217.1 - 0.0019 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGO22217.1 - 0.014 16.3 0.0 0.036 14.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.8 EGO22217.1 - 0.017 14.4 0.1 0.028 13.6 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family CoA_binding_2 PF13380.1 EGO22217.1 - 0.022 14.8 0.0 0.26 11.4 0.0 2.3 1 1 0 1 1 1 0 CoA binding domain NAD_binding_10 PF13460.1 EGO22217.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Brix PF04427.13 EGO22218.1 - 1.4e-44 152.0 0.0 2e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Remorin_C PF03763.8 EGO22218.1 - 0.031 13.7 7.4 0.06 12.8 5.1 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region Pkinase PF00069.20 EGO22219.1 - 9e-65 218.3 0.0 1.2e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22219.1 - 1.3e-36 126.0 0.0 1.8e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO22219.1 - 2.5e-06 26.6 0.0 4.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO22219.1 - 0.00033 19.7 0.1 0.0029 16.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO22219.1 - 0.0023 17.6 1.2 0.0057 16.4 0.3 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGO22219.1 - 0.084 11.6 0.5 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Guanylate_kin PF00625.16 EGO22220.1 - 8.8e-66 220.8 0.0 1.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EGO22220.1 - 2.3e-06 27.7 0.0 4.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGO22220.1 - 6.8e-06 26.0 0.0 2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO22220.1 - 0.0012 18.9 0.1 0.0059 16.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO22220.1 - 0.0029 16.7 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO22220.1 - 0.0031 18.3 0.2 0.011 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO22220.1 - 0.0045 17.2 0.0 0.028 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGO22220.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGO22220.1 - 0.055 13.6 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EGO22220.1 - 0.067 13.1 0.0 0.09 12.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EGO22220.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein NTPase_1 PF03266.10 EGO22220.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 NTPase Rad17 PF03215.10 EGO22220.1 - 0.094 11.3 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EGO22220.1 - 0.099 12.3 0.1 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF1640 PF07798.6 EGO22221.1 - 2.8e-64 216.3 10.5 3.2e-64 216.2 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2077 PF09850.4 EGO22221.1 - 0.14 11.5 3.0 3.3 7.0 0.0 3.0 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) ETRAMP PF09716.5 EGO22221.1 - 0.29 11.0 1.1 1.9 8.4 0.8 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) COG5 PF10392.4 EGO22221.1 - 1.8 8.5 8.3 2 8.3 0.5 3.0 1 1 2 3 3 3 0 Golgi transport complex subunit 5 FlaC_arch PF05377.6 EGO22221.1 - 1.8 8.5 6.0 1.6 8.6 0.6 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EGO22221.1 - 5.7 6.7 7.2 11 5.8 2.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DSPc PF00782.15 EGO22222.1 - 2.2e-33 114.6 0.0 3.3e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 EGO22222.1 - 2.7e-05 23.6 0.1 4.7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 EGO22222.1 - 0.00011 21.5 0.1 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGO22222.1 - 0.0018 17.2 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Nitr_red_bet_C PF14711.1 EGO22222.1 - 0.023 14.2 0.1 0.18 11.3 0.0 2.1 1 1 1 2 2 2 0 Respiratory nitrate reductase beta C-terminal Y_phosphatase3 PF13350.1 EGO22222.1 - 0.045 14.0 0.2 2.1 8.5 0.0 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family DSPn PF14671.1 EGO22222.1 - 0.14 12.1 0.1 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half ABC_membrane PF00664.18 EGO22223.1 - 6.9e-64 215.9 32.1 1.6e-37 129.4 8.2 3.0 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO22223.1 - 6.1e-53 178.8 0.0 2.6e-31 108.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGO22223.1 - 6.8e-08 32.0 0.0 0.036 13.3 0.0 4.2 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO22223.1 - 5e-06 26.7 1.5 1.3 8.9 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EGO22223.1 - 2.7e-05 23.6 0.0 0.24 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO22223.1 - 3e-05 23.4 0.8 0.085 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGO22223.1 - 3.8e-05 24.1 1.0 0.29 11.6 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EGO22223.1 - 4.6e-05 23.3 0.1 0.38 10.7 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EGO22223.1 - 8.6e-05 22.6 0.1 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EGO22223.1 - 0.0003 21.1 0.5 1.3 9.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 EGO22223.1 - 0.00055 18.9 0.0 0.63 8.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EGO22223.1 - 0.0017 17.5 0.1 1.4 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EGO22223.1 - 0.0022 17.1 0.2 0.34 9.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 EGO22223.1 - 0.011 15.2 0.4 6 6.2 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EGO22223.1 - 0.012 14.5 0.0 0.29 9.9 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 EGO22223.1 - 0.013 14.3 0.1 2 7.1 0.0 2.4 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 EGO22223.1 - 0.035 13.5 1.9 0.33 10.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGO22223.1 - 0.052 14.3 0.0 12 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGO22223.1 - 0.071 12.6 0.1 5.1 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EGO22223.1 - 0.075 12.8 0.4 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EGO22223.1 - 0.079 12.6 0.8 1.5 8.4 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase AAA_18 PF13238.1 EGO22223.1 - 0.085 13.1 0.0 22 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EGO22223.1 - 0.13 11.1 0.2 0.5 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 EGO22223.1 - 0.13 11.8 0.4 0.49 10.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EGO22223.1 - 0.54 10.4 3.1 16 5.6 0.3 3.4 2 1 0 2 2 2 0 AAA domain Peptidase_C12 PF01088.16 EGO22224.1 - 2.2e-56 190.4 0.0 3.2e-56 189.8 0.0 1.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HECT PF00632.20 EGO22225.1 - 9.7e-82 274.6 0.0 1.5e-81 274.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EGO22225.1 - 0.012 15.4 0.7 0.29 11.0 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UIM PF02809.15 EGO22225.1 - 0.8 9.4 4.3 1.1 9.0 0.2 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Aminotran_3 PF00202.16 EGO22226.1 - 5.7e-74 248.9 0.0 7.6e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SelR PF01641.13 EGO22227.1 - 1.2e-50 170.3 0.1 1.5e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 EGO22227.1 - 0.066 13.2 0.5 0.38 10.8 0.3 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EGO22227.1 - 0.068 13.1 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EGO22227.1 - 0.19 11.5 3.5 3.2 7.6 0.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Mss51 PF13824.1 EGO22227.1 - 0.24 11.3 1.9 5 7.0 0.1 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 NOB1_Zn_bind PF08772.6 EGO22227.1 - 0.88 9.4 2.9 0.75 9.6 0.6 1.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Tropomyosin_1 PF12718.2 EGO22228.1 - 3.7e-48 163.0 33.8 4.3e-48 162.8 23.4 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EGO22228.1 - 3.7e-14 52.3 33.3 2.8e-07 29.8 12.0 2.4 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 EGO22228.1 - 7.2e-05 22.6 31.8 0.0082 16.0 6.6 2.8 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.5 EGO22228.1 - 0.00041 20.4 2.9 0.00041 20.4 2.0 2.6 1 1 2 3 3 2 1 Tup N-terminal Myosin_tail_1 PF01576.14 EGO22228.1 - 0.00084 17.1 32.5 0.001 16.9 22.5 1.0 1 0 0 1 1 1 1 Myosin tail TMF_DNA_bd PF12329.3 EGO22228.1 - 0.012 15.4 34.8 0.024 14.4 10.6 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.6 EGO22228.1 - 0.02 14.7 8.2 0.02 14.7 5.7 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p ERM PF00769.14 EGO22228.1 - 0.038 13.5 33.9 0.019 14.4 20.4 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 EGO22228.1 - 0.038 13.1 31.5 0.35 10.0 7.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FliD_C PF07195.7 EGO22228.1 - 0.045 13.0 18.0 0.29 10.3 4.8 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.3 EGO22228.1 - 0.051 12.8 23.7 0.23 10.6 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.1 EGO22228.1 - 0.054 13.4 33.9 0.038 13.9 5.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 EGO22228.1 - 0.057 13.1 0.7 0.057 13.1 0.5 2.6 1 1 1 2 2 2 0 Laminin Domain II WEMBL PF05701.6 EGO22228.1 - 0.058 11.8 32.2 0.14 10.6 22.3 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light EzrA PF06160.7 EGO22228.1 - 0.059 11.5 24.8 0.29 9.2 5.5 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA IncA PF04156.9 EGO22228.1 - 0.065 12.8 26.4 0.17 11.4 18.3 1.7 1 1 0 1 1 1 0 IncA protein HGD-D PF06050.8 EGO22228.1 - 0.069 11.9 2.0 0.084 11.6 1.4 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component BLOC1_2 PF10046.4 EGO22228.1 - 0.072 13.2 22.3 0.59 10.3 4.6 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EGO22228.1 - 0.073 12.2 4.4 0.69 9.0 2.9 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EGO22228.1 - 0.093 10.5 15.8 0.11 10.3 10.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.1 EGO22228.1 - 0.11 12.5 23.5 0.054 13.4 14.8 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 EGO22228.1 - 0.11 12.2 26.2 0.73 9.5 9.9 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding MAD PF05557.8 EGO22228.1 - 0.11 10.5 24.8 0.63 8.0 17.2 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein FliJ PF02050.11 EGO22228.1 - 0.13 12.3 26.8 0.28 11.2 5.2 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein NAD_binding_4 PF07993.7 EGO22228.1 - 0.17 10.7 10.4 0.26 10.1 0.7 2.2 1 1 0 2 2 2 0 Male sterility protein AAA_27 PF13514.1 EGO22228.1 - 0.19 9.3 26.3 0.27 8.8 18.2 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EGO22228.1 - 0.19 10.7 33.1 0.19 10.7 13.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 EGO22228.1 - 0.2 11.5 27.1 2.1 8.2 5.5 3.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 EGO22228.1 - 0.21 11.3 27.7 0.18 11.6 7.5 2.6 1 1 2 3 3 3 0 Axonemal dynein light chain DUF1664 PF07889.7 EGO22228.1 - 0.24 11.2 15.7 0.042 13.6 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cast PF10174.4 EGO22228.1 - 0.24 9.3 31.8 2.7 5.9 22.0 2.0 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3287 PF11690.3 EGO22228.1 - 0.28 11.2 9.9 1 9.4 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF4407 PF14362.1 EGO22228.1 - 0.34 9.8 19.9 0.51 9.2 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TAFH PF07531.9 EGO22228.1 - 0.41 10.3 3.5 0.48 10.1 1.0 2.1 1 1 2 3 3 1 0 NHR1 homology to TAF DUF812 PF05667.6 EGO22228.1 - 0.43 9.0 26.4 0.77 8.1 10.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 EGO22228.1 - 0.54 8.6 24.0 1.8 6.8 7.6 1.9 1 1 1 2 2 2 0 AAA domain Peptidase_M32 PF02074.10 EGO22228.1 - 0.57 8.7 9.8 0.72 8.4 6.8 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase HalX PF08663.5 EGO22228.1 - 0.6 10.1 18.4 3.5 7.6 0.2 4.2 2 2 2 4 4 4 0 HalX domain Fib_alpha PF08702.5 EGO22228.1 - 0.6 10.2 16.8 3.7 7.6 3.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EGO22228.1 - 0.61 9.8 26.9 1 9.1 6.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) WXG100 PF06013.7 EGO22228.1 - 0.61 10.1 14.2 2.4 8.2 0.4 3.8 1 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF641 PF04859.7 EGO22228.1 - 0.67 9.7 21.1 0.13 11.9 3.1 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF948 PF06103.6 EGO22228.1 - 0.7 9.7 12.8 0.29 11.0 0.6 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.1 EGO22228.1 - 0.86 9.5 25.2 1.8 8.5 8.8 2.2 1 1 1 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.17 EGO22228.1 - 0.89 9.5 28.9 0.31 11.0 10.3 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Transketolase_N PF00456.16 EGO22228.1 - 0.89 8.2 9.3 1.1 8.0 6.4 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF3584 PF12128.3 EGO22228.1 - 1.1 6.4 28.8 2.3 5.4 20.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GP20 PF06810.6 EGO22228.1 - 1.2 8.6 30.0 0.68 9.3 9.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 EGO22228.1 - 1.3 7.8 23.5 0.83 8.5 14.0 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EGO22228.1 - 1.4 9.2 12.6 4.9 7.4 0.5 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EGO22228.1 - 1.5 8.3 27.6 2.1 7.8 8.2 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EGO22228.1 - 1.5 8.5 32.1 5.1 6.8 16.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HisKA_3 PF07730.8 EGO22228.1 - 1.5 9.2 11.4 27 5.2 2.5 3.9 1 1 2 3 3 3 0 Histidine kinase Laminin_I PF06008.9 EGO22228.1 - 1.6 8.0 24.6 4.9 6.3 6.6 2.2 1 1 0 1 1 1 0 Laminin Domain I Fmp27_WPPW PF10359.4 EGO22228.1 - 1.6 7.0 24.4 1.1 7.5 7.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3573 PF12097.3 EGO22228.1 - 2 6.9 5.5 2.5 6.6 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) IZUMO PF15005.1 EGO22228.1 - 2.1 8.3 7.9 2.3 8.2 4.6 1.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion LXG PF04740.7 EGO22228.1 - 2.3 7.9 21.7 1.1 8.9 6.8 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily THOC7 PF05615.8 EGO22228.1 - 2.4 8.4 27.0 2.1 8.5 6.4 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4164 PF13747.1 EGO22228.1 - 2.4 8.3 26.0 1.3 9.1 7.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF745 PF05335.8 EGO22228.1 - 2.8 7.4 22.2 2.1 7.8 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF3391 PF11871.3 EGO22228.1 - 2.9 8.0 12.8 1.2e+02 2.9 8.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Uds1 PF15456.1 EGO22228.1 - 3 7.8 24.0 2.7 7.9 5.2 2.7 1 1 2 3 3 3 0 Up-regulated During Septation CALCOCO1 PF07888.6 EGO22228.1 - 3.1 5.9 21.0 0.36 9.0 5.0 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Occludin_ELL PF07303.8 EGO22228.1 - 3.3 8.4 20.3 6.5 7.5 6.1 2.9 1 1 2 3 3 3 0 Occludin homology domain Striatin PF08232.7 EGO22228.1 - 3.5 7.9 24.5 3.1 8.1 9.1 2.7 1 1 1 2 2 2 0 Striatin family Mvb12 PF09452.5 EGO22228.1 - 3.6 7.8 9.6 1.7 8.8 2.3 2.4 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Cortex-I_coil PF09304.5 EGO22228.1 - 3.9 7.5 28.9 2.4 8.2 7.1 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF972 PF06156.8 EGO22228.1 - 4 7.8 24.3 0.35 11.2 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 EGO22228.1 - 4.5 6.9 20.1 1.1 8.9 3.6 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.7 EGO22228.1 - 5 7.5 18.5 0.86 10.0 2.2 3.7 2 2 1 3 3 3 0 SlyX PilJ PF13675.1 EGO22228.1 - 5.4 7.3 11.4 3 8.2 2.7 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4201 PF13870.1 EGO22228.1 - 5.5 6.3 27.1 50 3.2 6.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IFT46_B_C PF12317.3 EGO22228.1 - 5.6 6.2 12.8 0.46 9.8 3.9 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal BRE1 PF08647.6 EGO22228.1 - 5.8 6.9 30.9 2.6 8.0 7.4 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase PhoU PF01895.14 EGO22228.1 - 6.1 7.3 15.0 1.6 9.2 1.6 2.8 1 1 1 2 2 2 0 PhoU domain Adeno_PIX PF03955.9 EGO22228.1 - 6.6 7.2 13.2 5.1 7.6 2.5 2.8 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) MbeD_MobD PF04899.7 EGO22228.1 - 8.3 6.4 9.8 4.2 7.3 2.2 2.9 1 1 1 2 2 2 0 MbeD/MobD like DUF2408 PF10303.4 EGO22229.1 - 5.9e-61 204.4 0.1 1e-32 113.0 0.0 5.1 3 2 2 5 5 5 5 Protein of unknown function (DUF2408) PilJ PF13675.1 EGO22229.1 - 0.055 13.7 0.4 3.7 7.8 0.0 3.0 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2968 PF11180.3 EGO22229.1 - 0.059 12.7 0.6 0.16 11.3 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Trns_repr_metal PF02583.12 EGO22229.1 - 0.43 10.7 3.5 2.8 8.2 0.0 3.5 4 0 0 4 4 4 0 Metal-sensitive transcriptional repressor CK2S PF15011.1 EGO22229.1 - 0.58 9.9 3.9 0.85 9.3 0.2 3.0 3 1 0 3 3 3 0 Casein Kinase 2 substrate PQ-loop PF04193.9 EGO22230.1 - 6.8e-33 112.0 12.7 6e-20 70.5 0.9 3.0 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 EGO22230.1 - 0.00011 22.6 4.5 0.0099 16.3 1.2 2.7 2 1 0 2 2 2 2 ER lumen protein retaining receptor Shisa PF13908.1 EGO22230.1 - 0.01 16.0 0.4 0.018 15.2 0.0 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1352 PF07086.7 EGO22230.1 - 0.17 11.4 3.6 1.6 8.3 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1352) Helicase_C PF00271.26 EGO22232.1 - 1.5e-16 60.0 0.0 5.9e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO22232.1 - 7.8e-15 54.7 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EGO22232.1 - 0.00031 19.4 0.0 0.00042 19.0 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 EGO22232.1 - 0.099 12.4 0.6 0.48 10.2 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Kei1 PF08552.6 EGO22234.1 - 4.5e-41 140.6 3.7 8.1e-41 139.7 2.5 1.4 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 IF4E PF01652.13 EGO22235.1 - 7.9e-47 158.8 0.1 1.3e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Amelin PF05111.7 EGO22235.1 - 0.11 11.2 0.1 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) MMS19_C PF12460.3 EGO22236.1 - 5.4e-95 318.5 2.6 5.4e-94 315.2 0.2 2.4 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EGO22236.1 - 9.5e-92 306.9 0.0 7.5e-90 300.7 0.0 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EGO22236.1 - 8.2e-11 42.0 2.3 0.0031 17.7 0.0 6.0 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EGO22236.1 - 2.3e-06 27.9 5.1 0.0049 17.3 0.0 5.9 5 1 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 EGO22236.1 - 3.1e-06 26.8 4.1 0.06 13.4 0.1 5.0 4 0 0 4 4 4 2 HEAT repeat Tctex-1 PF03645.8 EGO22236.1 - 0.0024 17.6 0.0 0.99 9.2 0.0 2.7 2 0 0 2 2 2 2 Tctex-1 family Arm PF00514.18 EGO22236.1 - 0.017 14.9 6.3 18 5.3 0.0 6.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Rcd1 PF04078.8 EGO22237.1 - 1.5e-128 427.2 3.9 1.7e-128 426.9 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like UAA PF08449.6 EGO22238.1 - 8.8e-70 235.0 11.6 9.9e-70 234.8 8.0 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EGO22238.1 - 0.0059 15.7 0.7 0.01 14.9 0.3 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EGO22238.1 - 0.0077 16.2 20.3 0.015 15.3 3.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EGO22238.1 - 0.16 11.5 12.9 0.4 10.3 3.2 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family Nup35_RRM PF05172.8 EGO22239.1 - 3.9e-09 36.1 0.0 1.8e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EGO22239.1 - 0.0043 16.7 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Cation_efflux PF01545.16 EGO22240.1 - 4e-59 200.0 12.3 4e-59 200.0 8.5 2.6 2 1 0 2 2 2 1 Cation efflux family Fungal_trans PF04082.13 EGO22241.1 - 1.1e-14 53.9 1.0 1.9e-14 53.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_ab PF00006.20 EGO22242.1 - 9.9e-71 237.6 0.0 1.6e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO22242.1 - 1.5e-23 83.4 0.1 3.8e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO22242.1 - 4.2e-18 65.3 1.4 1.1e-17 64.0 1.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.16 EGO22243.1 - 1.5e-13 50.6 0.4 1.8e-13 50.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FF PF01846.14 EGO22244.1 - 3.4e-28 97.3 6.6 7.7e-11 41.7 0.0 6.2 5 1 1 6 6 6 4 FF domain WW PF00397.21 EGO22244.1 - 1.2e-13 50.5 13.4 2.6e-07 30.3 1.1 3.0 2 0 0 2 2 2 2 WW domain PHF5 PF03660.9 EGO22245.1 - 5.6e-51 171.1 8.0 6.2e-51 170.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EGO22245.1 - 0.27 11.0 14.7 0.047 13.5 4.6 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EGO22245.1 - 0.43 10.3 14.3 2.3 7.9 0.3 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EGO22245.1 - 1.3 8.7 14.1 0.034 13.8 3.7 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 EGO22245.1 - 6.6 4.2 6.4 7.2 4.1 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 EGO22245.1 - 9.6 6.0 13.0 10 5.9 4.9 2.7 1 1 0 1 1 1 0 zinc-ribbons ZZ PF00569.12 EGO22246.1 - 1e-16 60.1 57.7 1.4e-07 30.9 2.2 6.2 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.19 EGO22246.1 - 1.2e-08 34.4 0.0 2.4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Cwf_Cwc_15 PF04889.7 EGO22247.1 - 0.0038 16.9 0.5 0.0043 16.8 0.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Mus7 PF09462.5 EGO22248.1 - 8.9e-55 186.6 0.0 1.2e-54 186.2 0.0 1.0 1 0 0 1 1 1 1 Mus7/MMS22 family Phage_endo_I PF05367.6 EGO22249.1 - 0.054 12.8 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage endonuclease I DUF1771 PF08590.5 EGO22250.1 - 2.4e-13 49.8 4.0 2.4e-13 49.8 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EGO22250.1 - 2.4e-06 27.0 6.8 0.002 17.7 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EGO22250.1 - 1.9e-05 24.7 0.1 5.2e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Smr domain CDC27 PF09507.5 EGO22250.1 - 0.36 10.0 0.0 0.63 9.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C3H1 PF10650.4 EGO22250.1 - 0.63 9.5 3.3 7.9 6.0 0.5 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain FA_hydroxylase PF04116.8 EGO22251.1 - 1.3e-18 67.4 10.6 1.3e-18 67.4 7.4 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily But2 PF09792.4 EGO22253.1 - 1.9e-06 27.7 0.0 2.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DDE_3 PF13358.1 EGO22254.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L37ae PF01780.14 EGO22256.1 - 1.8e-40 136.6 9.9 2e-40 136.5 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGO22256.1 - 0.004 16.9 1.6 0.0061 16.3 1.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 EGO22256.1 - 0.0064 16.3 1.2 0.0083 15.9 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-FCS PF06467.9 EGO22256.1 - 0.03 13.9 1.1 0.83 9.3 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.10 EGO22256.1 - 0.03 14.0 3.0 0.89 9.3 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger Rsm1 PF08600.5 EGO22256.1 - 0.077 12.8 0.3 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Rsm1-like Elf1 PF05129.8 EGO22256.1 - 0.18 11.5 3.0 0.34 10.6 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.5 EGO22256.1 - 0.2 11.1 3.6 1 8.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_L44 PF00935.14 EGO22256.1 - 1.5 8.9 8.3 1.4 9.0 2.4 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 zf-H2C2_2 PF13465.1 EGO22256.1 - 5.4 7.4 5.8 3.6 8.0 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain DUF3328 PF11807.3 EGO22257.1 - 4e-15 56.0 4.6 5.9e-15 55.5 3.2 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGO22258.1 - 2.8e-14 53.3 0.3 4e-14 52.8 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) TBSV_P22 PF03558.8 EGO22258.1 - 0.13 11.6 0.3 0.32 10.3 0.1 1.7 1 1 1 2 2 2 0 TBSV core protein P21/P22 Acetyltransf_1 PF00583.19 EGO22259.1 - 7.4e-08 32.3 0.0 2.8e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGO22259.1 - 0.0094 15.8 0.0 0.087 12.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO22259.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO22259.1 - 0.012 15.7 0.0 0.045 13.9 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO22259.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GCFC PF07842.7 EGO22261.1 - 1.5e-82 277.0 11.2 2.4e-82 276.3 7.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EGO22261.1 - 1.9e-12 46.7 2.4 3.7e-12 45.8 1.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGO22261.1 - 4.1e-07 29.7 0.4 4.1e-07 29.7 0.3 2.2 3 0 0 3 3 3 1 DExH-box splicing factor binding site WD40 PF00400.27 EGO22262.1 - 6e-10 38.6 1.6 1.9e-05 24.3 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANTH PF07651.11 EGO22263.1 - 0.021 13.5 0.2 0.031 12.9 0.2 1.2 1 0 0 1 1 1 0 ANTH domain Tim44 PF04280.10 EGO22264.1 - 9.2e-31 106.8 0.4 2.3e-30 105.4 0.3 1.7 1 0 0 1 1 1 1 Tim44-like domain Sigma54_CBD PF04963.8 EGO22264.1 - 0.0081 15.6 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 factor, core binding domain OmpH PF03938.9 EGO22264.1 - 0.069 13.0 3.2 0.16 11.8 2.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3813 PF12758.2 EGO22264.1 - 2.6 8.2 6.8 1.6 8.8 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3813) Cyto_heme_lyase PF01265.12 EGO22265.1 - 2.9e-71 240.1 0.1 3.3e-71 239.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase RVP_2 PF08284.6 EGO22266.1 - 0.00078 19.3 0.0 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO22266.1 - 0.0051 17.2 0.0 0.0067 16.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO22266.1 - 0.033 13.9 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EGO22267.1 - 3.5e-08 33.4 0.1 3.5e-08 33.4 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO22267.1 - 8.3e-07 28.6 3.9 1.6e-06 27.7 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO22267.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO22267.1 - 0.095 12.4 2.4 0.33 10.7 1.7 1.9 1 0 0 1 1 1 0 Zinc knuckle Sugar_tr PF00083.19 EGO22272.1 - 5.6e-126 420.7 31.9 6.4e-126 420.5 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO22272.1 - 1.1e-24 86.7 60.9 7.2e-23 80.8 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dak1 PF02733.12 EGO22273.1 - 1.8e-111 371.8 0.5 2.5e-111 371.3 0.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGO22273.1 - 9.1e-38 129.6 1.9 1.3e-37 129.1 1.3 1.2 1 0 0 1 1 1 1 DAK2 domain UCH PF00443.24 EGO22274.1 - 1.2e-78 263.9 0.0 2.1e-78 263.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO22274.1 - 2.2e-21 76.5 0.0 1.6e-12 47.4 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGO22274.1 - 7.7e-13 48.6 0.4 3.5e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 DUSP domain Zn-ribbon_8 PF09723.5 EGO22274.1 - 0.17 11.8 1.8 2.9 7.9 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1712 PF08217.6 EGO22275.1 - 1.8e-22 79.3 0.0 2.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-CCCH PF00642.19 EGO22276.1 - 6.5e-11 41.6 15.4 5.3e-05 22.7 0.3 4.4 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MSP1_C PF07462.6 EGO22276.1 - 1.7 6.9 7.4 2.6 6.3 5.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nucleoplasmin PF03066.10 EGO22276.1 - 2.7 7.4 15.7 4.5 6.7 10.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EGO22276.1 - 4.9 6.7 11.4 7.4 6.1 7.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Antifungal_prot PF11402.3 EGO22276.1 - 8.4 6.6 7.6 6.4 7.0 1.4 2.8 2 0 0 2 2 2 0 Antifungal protein Pex14_N PF04695.8 EGO22276.1 - 9.5 6.2 8.7 0.23 11.4 0.8 2.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec1 PF00995.18 EGO22277.1 - 8.2e-135 450.6 0.0 1e-134 450.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DUF964 PF06133.6 EGO22277.1 - 0.17 11.8 1.5 0.81 9.7 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF964) AAA PF00004.24 EGO22278.1 - 5e-42 143.2 0.0 9.8e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO22278.1 - 6.7e-07 29.1 0.0 9.7e-06 25.3 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO22278.1 - 9.6e-07 28.9 0.1 5.9e-05 23.1 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO22278.1 - 5.6e-06 26.5 0.0 0.00099 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO22278.1 - 9.3e-06 25.6 0.0 3.7e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGO22278.1 - 1.4e-05 24.2 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGO22278.1 - 6.6e-05 22.5 1.6 0.00029 20.5 0.8 2.1 1 1 1 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EGO22278.1 - 0.00045 19.3 0.6 0.004 16.2 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EGO22278.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGO22278.1 - 0.0013 19.5 0.7 0.0029 18.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EGO22278.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGO22278.1 - 0.0023 17.1 0.0 0.0052 15.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EGO22278.1 - 0.0023 16.9 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EGO22278.1 - 0.0031 16.3 0.0 0.0056 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EGO22278.1 - 0.0037 17.5 0.1 0.015 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EGO22278.1 - 0.0037 17.1 0.4 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4200 PF13863.1 EGO22278.1 - 0.0045 16.9 0.6 0.0098 15.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) PhoH PF02562.11 EGO22278.1 - 0.0051 16.0 0.4 0.013 14.7 0.1 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.1 EGO22278.1 - 0.0054 16.6 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EGO22278.1 - 0.0055 16.8 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EGO22278.1 - 0.0074 15.8 0.2 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGO22278.1 - 0.01 15.3 0.0 0.037 13.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EGO22278.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGO22278.1 - 0.017 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO22278.1 - 0.023 14.0 0.3 0.087 12.2 0.2 2.0 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 EGO22278.1 - 0.031 13.3 0.7 0.087 11.9 0.0 2.0 3 0 0 3 3 3 0 KaiC TPR_MLP1_2 PF07926.7 EGO22278.1 - 0.042 13.5 0.2 0.093 12.4 0.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_30 PF13604.1 EGO22278.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO22278.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 EGO22278.1 - 0.057 12.2 0.3 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 EGO22278.1 - 0.063 12.1 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EGO22278.1 - 0.084 12.4 0.4 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGO22278.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EGO22278.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain GST_C PF00043.20 EGO22279.1 - 0.021 14.7 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO22279.1 - 0.043 13.7 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RCC1 PF00415.13 EGO22280.1 - 2.1e-11 43.8 5.9 1.2e-05 25.3 0.0 5.3 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO22280.1 - 6.9e-06 25.5 17.1 0.0033 17.0 0.5 5.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EGO22280.1 - 0.073 12.8 0.7 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EGO22280.1 - 0.11 12.2 0.3 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 F-box domain GST_N_3 PF13417.1 EGO22281.1 - 1.6e-14 53.8 0.0 3.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO22281.1 - 3.5e-11 42.9 0.0 6.6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO22281.1 - 0.0014 18.8 0.0 0.005 16.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO22281.1 - 0.036 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO22281.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C3HC4 PF00097.20 EGO22287.1 - 4e-06 26.3 12.9 9.3e-06 25.2 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO22287.1 - 0.00032 20.5 11.2 0.0011 18.7 7.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGO22287.1 - 0.00065 19.4 17.4 0.0013 18.4 11.6 1.9 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO22287.1 - 0.0028 17.6 14.5 0.0065 16.4 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO22287.1 - 0.054 13.2 14.4 0.4 10.4 9.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 EGO22287.1 - 0.2 11.2 8.3 0.36 10.3 5.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EGO22287.1 - 0.83 9.8 12.3 2.9 8.0 8.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Bap31 PF05529.7 EGO22287.1 - 1 8.7 3.8 1.5 8.2 2.6 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like zf-RING_UBOX PF13445.1 EGO22287.1 - 1.1 9.0 11.5 3 7.6 7.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EGO22287.1 - 1.4 8.7 6.4 3.6 7.4 4.4 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGO22287.1 - 3.7 7.4 11.5 8.6 6.2 7.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Actin PF00022.14 EGO22288.1 - 2e-29 102.1 0.0 6.5e-13 47.8 0.0 3.1 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 EGO22288.1 - 1.2e-05 24.1 0.5 5.7e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FAT PF02259.18 EGO22289.1 - 1.1e-118 396.2 12.3 1.5e-118 395.7 5.9 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EGO22289.1 - 8.2e-57 192.3 0.6 1.6e-56 191.4 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EGO22289.1 - 4.9e-49 166.3 0.7 2.2e-46 157.6 0.0 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EGO22289.1 - 9.4e-38 128.3 0.1 9.4e-38 128.3 0.1 3.1 3 0 0 3 3 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EGO22289.1 - 1e-21 77.0 15.9 3.4e-06 27.2 0.0 10.5 5 3 6 11 11 11 7 HEAT repeats HEAT PF02985.17 EGO22289.1 - 4.9e-16 57.3 16.6 0.016 15.2 0.0 11.6 11 0 0 11 11 11 4 HEAT repeat FATC PF02260.15 EGO22289.1 - 9.3e-16 56.9 0.5 2.1e-15 55.8 0.4 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EGO22289.1 - 5.6e-09 36.2 29.7 0.00035 20.9 0.0 12.9 14 2 3 17 17 14 1 HEAT-like repeat TPR_19 PF14559.1 EGO22289.1 - 5.9e-07 29.7 2.0 0.00044 20.5 0.2 4.0 4 0 0 4 4 2 1 Tetratricopeptide repeat CLASP_N PF12348.3 EGO22289.1 - 7.2e-07 28.7 3.0 1.8 7.8 0.0 6.4 5 2 2 7 7 7 1 CLASP N terminal Adaptin_N PF01602.15 EGO22289.1 - 2.2e-05 23.0 6.7 0.0087 14.4 0.8 4.2 2 1 1 3 3 3 2 Adaptin N terminal region TPR_14 PF13428.1 EGO22289.1 - 0.00073 19.9 3.1 0.095 13.3 0.1 4.8 4 0 0 4 4 2 1 Tetratricopeptide repeat Cohesin_HEAT PF12765.2 EGO22289.1 - 0.0011 18.8 2.2 0.056 13.4 0.1 4.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion TPR_11 PF13414.1 EGO22289.1 - 0.0021 17.6 3.3 0.029 14.0 0.1 3.8 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EGO22289.1 - 0.0062 16.3 4.2 0.39 10.7 0.5 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO22289.1 - 0.0065 17.1 0.4 0.0065 17.1 0.3 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22289.1 - 0.059 13.1 7.6 0.054 13.3 0.3 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat CBM_25 PF03423.8 EGO22289.1 - 0.088 12.9 0.3 0.26 11.4 0.2 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) TPR_6 PF13174.1 EGO22289.1 - 0.13 12.8 0.8 29 5.3 0.1 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO22289.1 - 0.24 11.0 1.8 4.5 7.0 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TRI12 PF06609.8 EGO22289.1 - 0.33 9.0 0.0 0.58 8.2 0.0 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) UME PF08064.8 EGO22289.1 - 2 8.3 9.2 1.1 9.1 0.6 4.4 3 2 1 5 5 5 0 UME (NUC010) domain DUF2154 PF09922.4 EGO22290.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.6 1 1 1 2 2 2 0 Cell wall-active antibiotics response protein (DUF2154) M20_dimer PF07687.9 EGO22291.1 - 3.8e-08 33.0 0.0 7.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EGO22291.1 - 2.3e-06 27.2 0.5 3.6e-06 26.6 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ-X PF14308.1 EGO22292.1 - 2.1e-56 190.4 0.5 2.1e-56 190.4 0.3 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGO22292.1 - 2.2e-26 91.3 3.2 6.5e-26 89.8 2.2 1.9 1 0 0 1 1 1 1 DnaJ domain HTH_38 PF13936.1 EGO22292.1 - 1.1 8.8 6.6 5.4 6.6 0.4 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Metal_resist PF13801.1 EGO22292.1 - 3.4 7.6 9.3 0.44 10.5 0.2 2.8 2 0 0 2 2 2 0 Heavy-metal resistance PspB PF06667.7 EGO22292.1 - 7.7 6.5 7.9 0.23 11.4 0.3 2.3 3 0 0 3 3 3 0 Phage shock protein B Carn_acyltransf PF00755.15 EGO22294.1 - 5.5e-143 477.1 0.0 6.3e-143 476.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CNH PF00780.17 EGO22295.1 - 8.2e-81 271.4 0.0 3.8e-80 269.2 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EGO22295.1 - 4.3e-43 146.4 0.0 7.7e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EGO22295.1 - 1.9e-30 106.0 0.0 4.1e-30 104.9 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EGO22295.1 - 1.1e-12 47.4 0.0 2.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EGO22295.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 PH domain Polysacc_deac_1 PF01522.16 EGO22296.1 - 2.2e-26 91.8 0.0 1.4e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase TPR_11 PF13414.1 EGO22298.1 - 4.6e-13 48.5 3.4 4.5e-06 26.2 0.7 3.3 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGO22298.1 - 4e-07 29.3 1.6 0.012 15.1 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO22298.1 - 8.8e-07 28.3 0.0 0.01 15.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO22298.1 - 0.0016 19.0 0.2 0.24 12.1 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO22298.1 - 0.0027 18.1 0.3 0.44 11.3 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22298.1 - 0.015 15.0 0.2 0.12 12.1 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TCRP1 PF14944.1 EGO22298.1 - 0.17 11.7 0.1 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 zf-CCHC_3 PF13917.1 EGO22300.1 - 1.6e-05 24.5 1.7 1.8e-05 24.3 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO22300.1 - 0.00023 20.9 6.4 0.00032 20.4 4.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DDE_3 PF13358.1 EGO22302.1 - 2.8e-07 30.3 0.7 4.1e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease CRAL_TRIO PF00650.15 EGO22304.1 - 7.8e-29 100.2 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO22304.1 - 0.00057 19.9 0.0 0.0021 18.1 0.0 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain TPT PF03151.11 EGO22305.1 - 2.1e-30 105.4 22.7 4.2e-29 101.1 5.3 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGO22305.1 - 2.9e-14 52.6 17.8 3.9e-14 52.2 12.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO22305.1 - 1.3e-09 38.1 30.9 9.6e-07 28.8 8.4 3.4 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EGO22305.1 - 0.024 13.7 2.0 0.29 10.2 0.0 2.4 2 1 0 2 2 2 0 Nucleotide-sugar transporter Ribosomal_S4e PF00900.15 EGO22306.1 - 6.4e-31 105.8 0.2 1.5e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGO22306.1 - 3.3e-21 74.8 3.8 1.1e-20 73.1 2.8 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EGO22306.1 - 1.9e-06 27.1 0.0 4.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGO22306.1 - 1.8e-05 24.2 4.0 6e-05 22.5 2.7 2.0 1 0 0 1 1 1 1 KOW motif RFXA_RFXANK_bdg PF15289.1 EGO22307.1 - 0.034 14.3 0.8 0.18 12.0 0.3 2.2 1 1 1 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Tmemb_14 PF03647.8 EGO22308.1 - 5.1e-16 58.8 7.4 6.4e-16 58.5 5.1 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C MtrC PF04211.8 EGO22308.1 - 0.42 9.5 4.6 0.45 9.5 3.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C zf-CCHC PF00098.18 EGO22311.1 - 1.7e-05 24.4 1.6 2.8e-05 23.8 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Pox_H7 PF04787.7 EGO22311.1 - 0.048 13.4 0.1 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Late protein H7 DUF2781 PF10914.3 EGO22312.1 - 1.9e-35 121.8 9.7 2.3e-35 121.5 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) WD40 PF00400.27 EGO22313.1 - 1.3e-10 40.7 0.1 0.00036 20.2 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EGO22313.1 - 0.012 13.7 0.0 0.11 10.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Glyco_hydro_47 PF01532.15 EGO22314.1 - 1.1e-131 439.6 0.0 1.3e-131 439.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF932 PF06067.6 EGO22314.1 - 0.089 12.0 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Evr1_Alr PF04777.8 EGO22315.1 - 2.9e-29 100.8 0.5 2.9e-29 100.8 0.4 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Med27 PF11571.3 EGO22315.1 - 0.087 12.9 0.9 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit 27 zf-ZPR1 PF03367.8 EGO22316.1 - 1.8e-94 313.2 0.2 1.1e-46 157.9 0.0 2.9 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EGO22316.1 - 0.0093 15.6 1.7 2 8.1 0.1 2.7 2 1 0 2 2 2 2 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 EGO22316.1 - 0.025 14.2 3.5 6.7 6.5 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EGO22316.1 - 0.026 14.3 5.4 2.9 7.8 0.6 3.1 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGO22316.1 - 0.17 11.8 5.0 8.1 6.4 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EGO22316.1 - 0.17 11.1 4.5 2.3 7.5 0.1 3.4 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGO22316.1 - 1.1 8.7 10.1 29 4.3 0.2 3.8 3 1 1 4 4 4 0 zinc-ribbon domain ADK_lid PF05191.9 EGO22316.1 - 4.2 7.1 7.3 7 6.4 0.0 3.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid C1_1 PF00130.17 EGO22316.1 - 9 6.1 8.6 12 5.7 0.6 2.8 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_28 PF02636.12 EGO22317.1 - 6e-37 127.3 0.0 9.8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EGO22317.1 - 0.00025 20.1 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EGO22317.1 - 0.015 15.8 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ChlamPMP_M PF07548.6 EGO22317.1 - 0.041 13.6 0.1 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Methyltransf_18 PF12847.2 EGO22318.1 - 0.00016 22.1 0.0 0.00029 21.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO22318.1 - 0.00021 21.6 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO22318.1 - 0.0031 17.1 0.1 0.0059 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO22318.1 - 0.026 14.2 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO22318.1 - 0.098 13.1 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SusD-like_3 PF14322.1 EGO22318.1 - 2.9 7.8 4.7 23 4.9 0.1 2.0 1 1 0 2 2 2 0 Starch-binding associating with outer membrane zf-ribbon_3 PF13248.1 EGO22320.1 - 0.07 12.3 1.4 0.12 11.6 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Myb_DNA-bind_4 PF13837.1 EGO22325.1 - 3.1e-07 30.4 0.0 9.9e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO22325.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_32 PF13565.1 EGO22326.1 - 0.02 15.6 0.0 0.028 15.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain zf-HIT PF04438.11 EGO22328.1 - 7.3e-10 38.3 11.3 1.4e-09 37.4 7.9 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-Apc11 PF12861.2 EGO22328.1 - 0.00024 20.8 0.8 0.00049 19.8 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tnp_zf-ribbon_2 PF13842.1 EGO22328.1 - 3.4 8.1 9.0 7.3 7.0 6.2 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Zip PF02535.17 EGO22329.1 - 1.1e-53 182.2 8.0 1.3e-53 182.0 5.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Peptidase_M28 PF04389.12 EGO22330.1 - 1.7e-20 73.5 0.0 4.2e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGO22330.1 - 4.5e-07 29.5 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L20 PF00453.13 EGO22333.1 - 0.057 13.3 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L20 Glyco_hydro_47 PF01532.15 EGO22334.1 - 1.9e-121 405.8 0.0 4.9e-121 404.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 FGGY_N PF00370.16 EGO22335.1 - 1.6e-59 201.2 0.0 5.3e-58 196.2 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EGO22335.1 - 2e-59 200.5 2.4 2.8e-59 200.0 1.6 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DEAD PF00270.24 EGO22336.1 - 3.7e-36 124.1 0.0 6.1e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO22336.1 - 1.4e-19 69.7 0.1 3.5e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGO22336.1 - 0.00037 20.3 0.0 0.0026 17.6 0.0 2.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_S10 PF00450.17 EGO22337.1 - 8.4e-65 219.5 0.1 2.3e-64 218.0 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase TPR_11 PF13414.1 EGO22338.1 - 1.6e-10 40.4 5.7 5.1e-06 26.0 0.2 2.9 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EGO22338.1 - 2.7e-08 33.6 10.6 1.9e-06 27.7 0.4 3.9 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO22338.1 - 9.4e-08 31.3 3.8 0.0061 16.1 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO22338.1 - 1e-05 25.0 11.9 0.073 13.0 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGO22338.1 - 2.4e-05 23.4 1.4 4.5e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 SHNi-TPR TPR_19 PF14559.1 EGO22338.1 - 0.00022 21.4 5.9 0.0018 18.5 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22338.1 - 0.00083 18.9 13.8 0.068 12.9 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO22338.1 - 0.0012 19.4 13.5 0.011 16.4 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO22338.1 - 0.0079 15.9 11.6 0.069 12.9 0.2 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO22338.1 - 0.012 15.7 0.0 3.2 8.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SF-assemblin PF06705.6 EGO22338.1 - 0.03 13.4 5.3 0.13 11.3 1.1 2.6 1 1 2 3 3 3 0 SF-assemblin/beta giardin Syntaxin-6_N PF09177.6 EGO22338.1 - 0.12 12.7 1.5 0.66 10.4 0.1 2.8 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Apc3 PF12895.2 EGO22338.1 - 0.13 12.4 7.5 0.25 11.4 0.4 3.1 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 EGO22338.1 - 0.19 10.8 8.8 0.22 10.6 2.0 2.9 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 EGO22338.1 - 1.1 10.1 12.5 10 7.0 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Aldedh PF00171.17 EGO22339.1 - 2.1e-13 49.4 3.6 8e-12 44.2 1.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family YjbE PF11106.3 EGO22339.1 - 4.8 7.2 12.4 6.3 6.8 1.1 2.7 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Paf1 PF03985.8 EGO22340.1 - 9.6e-61 205.8 0.0 1.1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Paf1 Baculo_VP39 PF04501.7 EGO22341.1 - 0.16 10.9 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 ELMO_CED12 PF04727.8 EGO22342.1 - 3.5e-29 101.5 0.1 5.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EGO22342.1 - 9.6e-14 51.4 0.6 6.4e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) DUF4327 PF14217.1 EGO22342.1 - 0.062 13.1 5.5 4.7 7.1 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4327) PROL5-SMR PF15621.1 EGO22344.1 - 1.2 9.5 7.6 0.076 13.4 0.8 2.3 2 1 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Aa_trans PF01490.13 EGO22345.1 - 6.7e-70 235.6 21.6 9.1e-70 235.1 15.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TspO_MBR PF03073.10 EGO22345.1 - 0.00058 19.3 1.1 0.0013 18.2 0.1 2.0 2 0 0 2 2 2 1 TspO/MBR family DUF202 PF02656.10 EGO22345.1 - 0.81 9.9 0.1 0.81 9.9 0.0 4.3 3 2 2 5 5 5 0 Domain of unknown function (DUF202) SUZ PF12752.2 EGO22346.1 - 6.5e-16 58.6 4.0 1.3e-15 57.6 2.8 1.5 1 1 0 1 1 1 1 SUZ domain R3H PF01424.17 EGO22346.1 - 0.00018 21.1 0.2 0.00035 20.1 0.2 1.5 1 0 0 1 1 1 1 R3H domain DUF3599 PF12206.3 EGO22346.1 - 0.035 14.3 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) Macoilin PF09726.4 EGO22347.1 - 1.3 7.1 2.8 1.4 7.1 2.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1183 PF06682.7 EGO22347.1 - 3.1 7.3 8.9 6.2 6.3 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Acyl-CoA_dh_M PF02770.14 EGO22348.1 - 0.039 13.4 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGO22348.1 - 0.09 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain RNA_pol_Rpb4 PF03874.11 EGO22350.1 - 4.3e-15 55.7 0.0 5.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.15 EGO22351.1 - 2.5e-17 63.2 0.0 1e-08 35.5 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase FGGY_N PF00370.16 EGO22352.1 - 6.6e-25 87.8 0.0 2.8e-16 59.5 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EGO22352.1 - 1.2e-18 67.4 0.0 2.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 EGO22352.1 - 0.12 11.6 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF791 PF05631.9 EGO22353.1 - 0.13 10.9 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF791) LRR_4 PF12799.2 EGO22354.1 - 0.24 11.0 2.8 8.4 6.1 0.3 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO22354.1 - 0.83 9.4 5.5 2.6 7.8 0.5 3.3 3 0 0 3 3 3 0 Leucine rich repeat DDE_3 PF13358.1 EGO22355.1 - 1.2e-07 31.6 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease AIF-MLS PF14962.1 EGO22356.1 - 0.98 9.0 4.6 0.84 9.2 2.1 1.6 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Pkinase PF00069.20 EGO22358.1 - 2e-63 213.9 0.0 2.4e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22358.1 - 9.3e-44 149.4 0.0 1.2e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO22358.1 - 3.4e-05 22.9 0.0 5.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO22358.1 - 0.00082 19.1 0.2 0.015 15.0 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGO22358.1 - 0.0047 16.0 0.0 0.0064 15.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 EGO22358.1 - 0.047 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain WaaY PF06176.6 EGO22358.1 - 0.047 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.22 EGO22359.1 - 6.6e-46 156.6 0.0 1.4e-45 155.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EGO22359.1 - 1.1e-28 99.9 0.6 5.1e-28 97.7 0.1 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EGO22359.1 - 1.9e-05 23.9 0.3 0.00014 21.1 0.0 2.5 2 0 0 2 2 2 1 FATC domain F-box-like PF12937.2 EGO22362.1 - 8e-11 41.4 1.0 1.9e-10 40.3 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO22362.1 - 0.014 15.0 0.5 0.09 12.4 0.2 2.5 2 1 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 EGO22362.1 - 0.017 14.8 0.3 0.081 12.6 0.1 2.2 2 1 0 2 2 2 0 F-box-like domain LRR_4 PF12799.2 EGO22362.1 - 0.028 14.0 0.1 4.1 7.1 0.0 4.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO22362.1 - 0.028 14.1 1.5 1.9 8.3 0.0 3.8 2 1 2 4 4 4 0 Leucine rich repeat Coatomer_E PF04733.9 EGO22363.1 - 4.6e-40 137.6 0.4 5.3e-40 137.4 0.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_9 PF13371.1 EGO22363.1 - 0.0011 18.7 1.4 0.073 12.9 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO22363.1 - 0.0047 16.7 1.6 0.77 9.8 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO22363.1 - 0.038 13.6 0.7 0.72 9.5 0.0 2.9 2 1 2 4 4 3 0 TPR repeat TPR_4 PF07721.9 EGO22363.1 - 0.12 12.8 6.7 8.9 7.0 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO22363.1 - 0.15 12.4 7.4 0.68 10.3 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGO22363.1 - 0.17 11.8 6.1 2.4 8.0 2.4 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO22363.1 - 0.37 11.5 12.7 31 5.5 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat HEAT_PBS PF03130.11 EGO22363.1 - 0.38 11.3 5.8 16 6.2 0.3 3.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat An_peroxidase PF03098.10 EGO22364.1 - 1.1e-74 251.6 0.1 5e-71 239.6 0.1 3.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGO22364.1 - 4.9e-09 35.2 0.0 8.5e-09 34.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF676 PF05057.9 EGO22365.1 - 6.5e-41 140.0 0.0 1e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGO22365.1 - 8.5e-06 25.4 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO22365.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGO22365.1 - 0.00048 19.9 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO22365.1 - 0.06 13.2 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family hNIFK_binding PF12196.3 EGO22366.1 - 0.065 12.6 0.8 0.26 10.6 0.1 2.3 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK SAP PF02037.22 EGO22368.1 - 0.0088 15.5 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain Trehalase_Ca-bi PF07492.6 EGO22368.1 - 0.031 13.5 0.9 0.081 12.2 0.6 1.6 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain Pkinase PF00069.20 EGO22370.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PALP PF00291.20 EGO22373.1 - 3.4e-52 177.5 0.5 4.1e-52 177.3 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOPA_dioxygen PF08883.6 EGO22374.1 - 7.3e-25 87.0 0.1 8.8e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DOPA_dioxygen PF08883.6 EGO22376.1 - 9.3e-32 109.2 0.1 1.1e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ADH_N PF08240.7 EGO22379.1 - 5.9e-27 93.5 0.6 5.9e-27 93.5 0.4 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO22379.1 - 9.4e-15 54.3 0.0 1.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EGO22379.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 EGO22379.1 - 0.031 15.1 0.0 0.056 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EGO22379.1 - 0.12 12.3 0.2 0.34 10.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EGO22380.1 - 7.8e-14 51.7 0.0 5.1e-08 33.1 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO22380.1 - 3.1e-12 45.6 1.1 3.2e-05 23.5 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO22380.1 - 5.3e-10 39.5 0.4 1.8e-07 31.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO22380.1 - 8e-10 38.0 0.9 0.0007 19.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGO22380.1 - 5.8e-09 35.9 0.2 0.005 17.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Filament PF00038.16 EGO22380.1 - 0.011 15.1 0.6 0.022 14.2 0.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein KilA-N PF04383.8 EGO22380.1 - 0.039 13.5 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 KilA-N domain Pox_A_type_inc PF04508.7 EGO22380.1 - 0.88 9.5 6.5 0.39 10.6 0.2 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat WD40 PF00400.27 EGO22381.1 - 6.6e-54 177.9 8.3 1.4e-09 37.4 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGO22381.1 - 1e-12 47.0 1.5 3.1e-12 45.5 1.1 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EGO22381.1 - 0.004 16.2 0.1 6.7 5.7 0.0 3.2 2 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EGO22381.1 - 0.089 10.9 2.1 2 6.4 0.1 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Pkinase PF00069.20 EGO22382.1 - 5.3e-59 199.4 0.1 1.6e-39 135.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22382.1 - 1.4e-24 86.5 1.7 3.4e-19 68.9 0.0 2.3 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO22382.1 - 2.9e-05 23.1 1.2 0.00023 20.2 0.1 2.8 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EGO22382.1 - 0.00084 18.4 0.2 0.0023 17.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGO22382.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EGO22382.1 - 0.0084 15.8 0.3 0.24 11.1 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO22382.1 - 0.026 13.8 1.8 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Orbi_NS1 PF01718.11 EGO22382.1 - 0.04 11.9 0.1 0.055 11.4 0.1 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Pkinase_C PF00433.19 EGO22382.1 - 0.04 14.4 0.4 0.04 14.4 0.3 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EGO22382.1 - 0.14 10.9 0.1 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EGO22385.1 - 1.1e-67 227.9 0.0 1.3e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22385.1 - 1.8e-53 181.2 0.0 2.1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO22385.1 - 0.00095 18.5 0.0 0.0031 16.8 0.0 1.7 1 1 1 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 EGO22385.1 - 0.031 13.1 0.1 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EGO22385.1 - 0.04 12.9 0.0 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO22385.1 - 0.045 12.6 0.0 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 EGO22385.1 - 0.06 12.6 0.1 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF728 PF05304.7 EGO22386.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Glyco_hydro_18 PF00704.23 EGO22388.1 - 1.2e-08 34.8 1.2 1.5e-08 34.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3836 PF12930.2 EGO22389.1 - 0.071 12.6 1.0 0.093 12.2 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Methyltransf_23 PF13489.1 EGO22390.1 - 1.8e-23 83.0 0.0 2.7e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO22390.1 - 9.4e-17 61.3 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO22390.1 - 1.5e-13 51.0 0.0 5e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO22390.1 - 7.2e-13 48.3 0.3 1.1e-05 25.0 0.2 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGO22390.1 - 1.2e-12 48.3 0.0 1.9e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO22390.1 - 2.5e-09 36.6 0.0 1.4e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGO22390.1 - 1.9e-06 28.1 0.0 3.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO22390.1 - 9.2e-05 22.4 0.1 0.00041 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO22390.1 - 0.00013 21.1 0.1 0.00034 19.8 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EGO22390.1 - 0.00014 20.6 0.0 0.0018 17.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EGO22390.1 - 0.0022 17.4 0.1 0.009 15.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.15 EGO22390.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EGO22390.1 - 0.028 14.1 0.1 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGO22390.1 - 0.041 13.2 0.3 0.16 11.3 0.2 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TehB PF03848.9 EGO22390.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB E1-E2_ATPase PF00122.15 EGO22391.1 - 1.4e-50 171.4 3.2 1.4e-50 171.4 2.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGO22391.1 - 6.9e-38 131.2 0.3 3.5e-37 128.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGO22391.1 - 5.3e-26 90.5 0.0 2.3e-12 46.8 0.0 2.8 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 EGO22391.1 - 1.7e-12 47.8 0.0 6.3e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO22391.1 - 0.00019 21.0 0.6 0.0069 15.9 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4600 PF15372.1 EGO22392.1 - 0.059 13.5 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) PH_10 PF15411.1 EGO22393.1 - 6.9e-28 97.1 0.0 1.2e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EGO22393.1 - 2.5e-05 24.0 2.5 4.9e-05 23.0 1.7 1.5 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 EGO22393.1 - 0.0006 19.5 0.4 0.0029 17.2 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-rbx1 PF12678.2 EGO22393.1 - 0.0079 16.2 0.3 0.049 13.7 0.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO22393.1 - 0.0093 15.6 1.0 0.023 14.4 0.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO22393.1 - 0.02 14.5 1.2 0.035 13.7 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 EGO22393.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain DOPA_dioxygen PF08883.6 EGO22395.1 - 3.2e-29 101.0 0.1 4.3e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family NFRKB_winged PF14465.1 EGO22398.1 - 0.042 13.6 0.1 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 NFRKB Winged Helix-like MULE PF10551.4 EGO22399.1 - 0.0017 18.4 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.12 EGO22399.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Transposase DOPA_dioxygen PF08883.6 EGO22400.1 - 5.1e-31 106.8 0.1 6.7e-31 106.4 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PMT PF02366.13 EGO22402.1 - 1.3e-79 267.0 18.4 2.9e-79 265.9 12.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGO22402.1 - 4e-14 52.5 1.2 6.4e-14 51.9 0.8 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EGO22402.1 - 2.3e-07 30.8 14.0 2.3e-07 30.8 9.7 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Fascin PF06268.8 EGO22402.1 - 0.13 12.3 0.1 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Fascin domain PX PF00787.19 EGO22403.1 - 1.3e-16 60.3 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 PX domain NYD-SP28 PF14772.1 EGO22403.1 - 0.079 13.0 3.6 0.13 12.3 0.4 2.4 2 1 0 2 2 2 0 Sperm tail Vps5 PF09325.5 EGO22404.1 - 5.6e-68 228.7 8.9 7.8e-68 228.2 6.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGO22404.1 - 8.4e-25 86.7 0.0 4.3e-24 84.4 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EGO22404.1 - 0.00022 20.5 2.7 0.041 13.1 0.1 2.2 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein BAR PF03114.13 EGO22404.1 - 0.0004 19.9 5.9 0.00059 19.4 4.1 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EGO22404.1 - 0.15 11.3 4.6 0.83 8.9 3.2 2.0 1 1 0 1 1 1 0 Arfaptin-like domain TMCO5 PF14992.1 EGO22404.1 - 0.2 10.7 3.7 0.66 9.0 0.3 2.2 2 0 0 2 2 2 0 TMCO5 family ERG4_ERG24 PF01222.12 EGO22405.1 - 7e-128 426.8 25.5 8e-128 426.6 17.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EGO22405.1 - 0.0042 17.1 0.1 0.0042 17.1 0.1 3.6 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 EGO22405.1 - 0.013 15.7 0.1 0.051 13.7 0.1 2.0 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EGO22405.1 - 0.039 13.2 14.0 0.093 12.0 9.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DWNN PF08783.6 EGO22406.1 - 3e-30 103.9 0.3 3e-30 103.9 0.2 2.0 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 EGO22406.1 - 1.2e-07 31.0 1.9 2.7e-07 29.9 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO22406.1 - 2.5e-05 23.9 2.0 2.5e-05 23.9 1.4 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EGO22406.1 - 0.00057 19.8 7.9 0.00057 19.8 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 EGO22406.1 - 0.0034 17.0 0.2 0.0034 17.0 0.1 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.1 EGO22406.1 - 0.0072 16.1 6.5 0.0072 16.1 4.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-CCHC_5 PF14787.1 EGO22406.1 - 0.047 13.1 7.2 0.14 11.6 0.3 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-H2C2_2 PF13465.1 EGO22406.1 - 0.3 11.4 5.8 3.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_3 PF13920.1 EGO22406.1 - 0.32 10.7 10.4 0.028 14.1 3.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO22406.1 - 0.74 9.5 7.9 1.7 8.3 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO22406.1 - 1.7 8.4 12.6 0.18 11.5 4.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain DnaJ PF00226.26 EGO22407.1 - 3.2e-25 87.6 0.2 5.6e-25 86.8 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EGO22407.1 - 6.5e-15 55.3 0.3 3.3e-14 53.0 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) DNA_binding_1 PF01035.15 EGO22408.1 - 5.5e-16 58.0 0.2 7.1e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain F-box-like PF12937.2 EGO22409.1 - 0.00015 21.3 0.1 0.00033 20.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like MIT PF04212.13 EGO22409.1 - 0.0023 17.8 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EGO22409.1 - 0.0031 17.3 0.1 0.011 15.5 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO22409.1 - 0.0057 16.2 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 TPR repeat F-box PF00646.28 EGO22409.1 - 0.0069 16.0 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 EGO22409.1 - 0.016 14.7 0.1 0.057 13.0 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 EGO22411.1 - 5.3e-10 38.7 2.7 0.75 9.7 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Clr2 PF10383.4 EGO22412.1 - 0.0045 16.9 0.0 0.049 13.6 0.0 2.4 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 TPR_19 PF14559.1 EGO22413.1 - 2.3e-08 34.2 1.0 1.4e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO22413.1 - 2.9e-08 34.1 0.4 5.8e-07 30.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO22413.1 - 1.4e-07 31.5 1.4 0.054 14.1 0.1 4.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO22413.1 - 1.3e-05 24.7 0.5 5.9e-05 22.6 0.1 2.2 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGO22413.1 - 9.2e-05 22.0 0.0 2.3 8.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EGO22413.1 - 0.00017 21.5 1.6 0.24 11.3 1.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22413.1 - 0.0013 18.3 0.0 0.94 9.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO22413.1 - 0.0037 17.1 1.0 0.59 10.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO22413.1 - 0.013 15.4 0.1 0.079 12.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGO22413.1 - 0.026 14.7 0.4 0.14 12.4 0.0 2.5 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO22413.1 - 0.031 14.7 0.2 1.9 9.1 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO22413.1 - 0.14 12.3 0.1 1.4 9.1 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EGO22413.1 - 0.21 11.7 1.6 1 9.5 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat MBOAT PF03062.14 EGO22414.1 - 9.9e-35 120.1 4.7 9.9e-35 120.1 3.2 2.6 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGO22414.1 - 2.2e-05 24.4 3.3 2.2e-05 24.4 2.3 2.2 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family dCMP_cyt_deam_1 PF00383.17 EGO22415.1 - 1e-22 79.7 0.1 1.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGO22415.1 - 0.0029 17.4 1.8 0.047 13.5 1.2 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase Peptidase_S9_N PF02897.10 EGO22416.1 - 5.1e-89 298.7 4.9 6.8e-89 298.3 3.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EGO22416.1 - 2.7e-54 183.6 0.0 5.5e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGO22416.1 - 0.0047 16.5 0.8 0.034 13.7 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1890 PF09001.6 EGO22416.1 - 0.58 10.1 2.3 2.3 8.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) RED_N PF07808.8 EGO22417.1 - 1.4e-09 37.5 2.8 2e-09 37.0 1.9 1.3 1 0 0 1 1 1 1 RED-like protein N-terminal region DUF4148 PF13663.1 EGO22417.1 - 0.066 13.0 0.6 0.066 13.0 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) MMgT PF10270.4 EGO22418.1 - 2.9e-08 34.0 0.0 3.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Abhydrolase_6 PF12697.2 EGO22420.1 - 4.6e-06 26.6 0.1 6.8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3328 PF11807.3 EGO22421.1 - 7.5e-06 25.7 2.8 9.1e-06 25.5 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2524 PF10732.4 EGO22422.1 - 0.04 14.0 0.4 0.054 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) MA3 PF02847.12 EGO22423.1 - 0.11 12.1 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 MA3 domain Pkinase PF00069.20 EGO22424.1 - 4.2e-11 42.4 0.0 1.4e-08 34.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22424.1 - 0.025 13.6 0.0 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase gag-asp_proteas PF13975.1 EGO22425.1 - 0.022 14.5 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Siva PF05458.7 EGO22425.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Rogdi_lz PF10259.4 EGO22425.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein zf-CCHC PF00098.18 EGO22426.1 - 4.3e-08 32.7 2.7 7.4e-08 31.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO22426.1 - 0.025 14.2 3.4 0.042 13.5 2.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO22426.1 - 0.027 14.1 1.4 0.071 12.7 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Zn_Tnp_IS91 PF14319.1 EGO22426.1 - 0.032 13.7 0.3 0.049 13.1 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF2524 PF10732.4 EGO22428.1 - 0.04 14.0 0.4 0.054 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Myb_DNA-binding PF00249.26 EGO22430.1 - 1.1e-35 121.4 7.1 1.3e-12 47.5 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO22430.1 - 2e-35 120.6 3.8 3.5e-15 55.8 0.1 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO22430.1 - 9.6 6.4 8.2 20 5.3 0.5 4.4 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Abhydrolase_6 PF12697.2 EGO22431.1 - 3.4e-14 53.2 0.0 4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO22431.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGO22431.1 - 0.0015 18.8 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGO22431.1 - 0.0046 16.5 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGO22431.1 - 0.006 16.3 0.0 0.0073 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zw10 PF06248.8 EGO22432.1 - 1e-13 50.3 0.0 6.7e-06 24.5 0.0 3.2 2 1 0 3 3 3 3 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EGO22432.1 - 3.3e-10 39.6 0.1 6.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Rep_fac_C PF08542.6 EGO22433.1 - 9.7e-22 76.7 0.0 2.3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EGO22433.1 - 2.3e-17 63.4 0.0 3.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGO22433.1 - 1.1e-15 57.6 0.0 1.6e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGO22433.1 - 4.3e-10 38.9 0.0 2.6e-08 33.0 0.0 2.4 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGO22433.1 - 3.6e-07 30.1 0.1 2.2e-06 27.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO22433.1 - 1.3e-06 28.5 0.7 0.0006 19.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO22433.1 - 1.3e-05 24.8 0.0 3.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EGO22433.1 - 2.2e-05 23.5 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EGO22433.1 - 5.3e-05 22.8 0.1 0.00027 20.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO22433.1 - 6.7e-05 22.9 0.0 0.00054 19.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGO22433.1 - 7.1e-05 21.9 0.0 0.00017 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EGO22433.1 - 0.00012 21.5 0.0 0.00036 20.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 EGO22433.1 - 0.00014 21.5 0.4 0.0023 17.5 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGO22433.1 - 0.00028 20.6 0.1 0.0016 18.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGO22433.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EGO22433.1 - 0.0024 17.3 0.2 0.025 14.0 0.2 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.1 EGO22433.1 - 0.0092 15.9 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EGO22433.1 - 0.012 15.4 0.0 0.085 12.6 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EGO22433.1 - 0.015 14.7 0.1 0.04 13.3 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EGO22433.1 - 0.015 14.8 0.2 0.031 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO22433.1 - 0.015 14.6 0.1 0.057 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGO22433.1 - 0.02 14.0 0.0 0.16 11.1 0.0 2.1 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 EGO22433.1 - 0.026 13.3 0.1 0.099 11.4 0.0 2.0 1 1 0 2 2 2 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 EGO22433.1 - 0.028 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 EGO22433.1 - 0.05 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EGO22433.1 - 0.052 14.3 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 EGO22433.1 - 0.064 12.1 0.1 1.5 7.6 0.1 2.1 1 1 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 EGO22433.1 - 0.065 12.6 0.2 4.4 6.6 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain T2SE PF00437.15 EGO22433.1 - 0.067 12.0 0.0 0.18 10.6 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein TPR_6 PF13174.1 EGO22433.1 - 0.087 13.3 1.0 2.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.1 EGO22433.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 EGO22434.1 - 0.00045 19.8 0.1 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGO22434.1 - 0.38 10.4 2.1 6.3 6.5 0.4 2.8 2 1 0 2 2 2 0 F-box domain FliT PF05400.8 EGO22435.1 - 0.052 13.9 1.4 0.068 13.5 0.9 1.2 1 0 0 1 1 1 0 Flagellar protein FliT DUF2762 PF10960.3 EGO22435.1 - 4 7.2 9.3 1.7 8.3 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) CTD_bind PF04818.8 EGO22436.1 - 0.00068 19.8 0.2 0.0026 17.9 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase II-binding domain. Death PF00531.17 EGO22436.1 - 0.13 12.0 0.1 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Death domain Cript PF10235.4 EGO22438.1 - 3.6e-22 78.5 4.0 3.6e-22 78.5 2.8 1.5 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.1 EGO22438.1 - 0.019 14.4 13.5 2.3 7.8 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EGO22438.1 - 0.059 13.2 14.2 0.14 11.9 7.0 2.5 1 1 1 2 2 2 0 Double zinc ribbon stn_TNFRSF12A PF12191.3 EGO22438.1 - 0.1 12.6 1.2 0.16 12.0 0.8 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Gin PF10764.4 EGO22438.1 - 0.19 11.4 7.4 4.6 7.0 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DUF1272 PF06906.6 EGO22438.1 - 0.49 10.2 6.4 0.39 10.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) C1_1 PF00130.17 EGO22438.1 - 0.53 10.0 12.2 3.3 7.4 3.4 3.0 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sgf11 PF08209.6 EGO22438.1 - 0.57 9.5 6.1 5.7 6.3 0.2 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.7 EGO22438.1 - 0.68 9.7 9.9 2.1 8.1 3.9 2.3 2 0 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.1 EGO22438.1 - 0.93 9.2 14.2 3.6 7.4 0.5 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 EGO22438.1 - 1.5 8.1 10.9 5.2 6.4 2.7 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DUF2039 PF10217.4 EGO22438.1 - 1.7 8.6 14.3 0.35 10.8 5.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) HypA PF01155.14 EGO22438.1 - 2.7 7.7 6.6 2.3 7.9 2.5 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-dskA_traR PF01258.12 EGO22438.1 - 6.4 6.6 8.9 7.1 6.4 0.1 3.3 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_3 PF13920.1 EGO22438.1 - 7.7 6.2 14.4 1.2e+02 2.5 5.2 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.9 EGO22438.1 - 8.3 6.1 10.3 11 5.7 0.1 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid F-box PF00646.28 EGO22439.1 - 0.11 12.1 0.3 0.31 10.7 0.2 1.7 1 0 0 1 1 1 0 F-box domain Glucos_trans_II PF14264.1 EGO22440.1 - 0.042 12.8 0.1 0.047 12.6 0.1 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII Orthoreo_P10 PF07204.6 EGO22440.1 - 0.062 13.0 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 WD40 PF00400.27 EGO22441.1 - 1.1e-36 123.3 16.4 4.9e-09 35.7 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Methyltransf_16 PF10294.4 EGO22441.1 - 8.8e-17 61.0 0.0 2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO22441.1 - 2.6e-06 27.9 0.0 5.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO22441.1 - 0.0047 16.3 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGO22441.1 - 0.02 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EGO22441.1 - 0.028 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G SIR2 PF02146.12 EGO22442.1 - 8.5e-26 90.7 0.0 4.9e-25 88.2 0.0 1.9 1 1 0 1 1 1 1 Sir2 family DUF364 PF04016.7 EGO22442.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF364) DUF4451 PF14616.1 EGO22443.1 - 0.00029 20.5 10.6 0.13 12.0 0.7 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4451) zf-CW PF07496.10 EGO22443.1 - 1.3 8.7 8.1 1.8 8.3 0.9 2.7 2 0 0 2 2 2 0 CW-type Zinc Finger DUF3279 PF11682.3 EGO22443.1 - 7.9 6.0 9.6 0.38 10.3 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) PGM_PMM_I PF02878.11 EGO22445.1 - 7.3e-39 132.4 0.2 1.1e-38 131.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGO22445.1 - 8.5e-26 90.2 0.0 2.1e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGO22445.1 - 2.7e-14 53.3 0.0 1e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGO22445.1 - 6.8e-08 32.4 0.0 2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Carb_kinase PF01256.12 EGO22446.1 - 8.8e-43 146.3 0.2 2.8e-40 138.1 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate kinase Phos_pyr_kin PF08543.7 EGO22446.1 - 0.061 12.4 0.0 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase FRG1 PF06229.7 EGO22447.1 - 0.0044 16.4 0.1 0.32 10.4 0.0 2.1 2 0 0 2 2 2 2 FRG1-like family Agglutinin PF07468.6 EGO22447.1 - 0.03 14.3 0.1 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Agglutinin Fascin PF06268.8 EGO22447.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Fascin domain DUF4468 PF14730.1 EGO22447.1 - 0.078 12.6 0.9 0.17 11.5 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Coronavirus_5 PF05528.6 EGO22450.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein DUF2393 PF09624.5 EGO22452.1 - 0.031 13.7 0.2 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) WD40 PF00400.27 EGO22453.1 - 0.00046 19.9 1.3 0.18 11.7 0.0 3.0 3 2 0 3 3 3 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGO22453.1 - 0.0085 14.4 0.0 0.0091 14.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EGO22453.1 - 0.049 13.0 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 PQQ-like domain Corona_M PF01635.13 EGO22453.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF3632 PF12311.3 EGO22456.1 - 3.1e-06 27.1 0.1 7e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Myb_DNA-bind_3 PF12776.2 EGO22457.1 - 1.9e-07 31.5 0.2 3.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO22457.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BTB PF00651.26 EGO22458.1 - 1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Acyltransferase PF01553.16 EGO22458.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase Glyco_hydro_16 PF00722.16 EGO22459.1 - 1.5e-07 30.9 0.0 3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EamA PF00892.15 EGO22460.1 - 7.9e-08 32.3 4.4 7.9e-08 32.3 3.1 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGO22460.1 - 3.8e-05 23.8 0.9 3.8e-05 23.8 0.6 3.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EGO22460.1 - 6.4e-05 22.6 18.0 0.0068 16.0 1.0 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF914 PF06027.7 EGO22460.1 - 0.00028 19.8 9.9 0.003 16.4 4.6 2.3 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGO22460.1 - 0.00048 19.1 7.5 0.0021 17.0 0.1 2.8 2 1 0 3 3 3 2 UAA transporter family MFS_1 PF07690.11 EGO22462.1 - 1.1e-22 80.3 28.7 1.1e-22 80.3 19.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MMPL PF03176.10 EGO22462.1 - 2.2 6.9 7.6 3 6.4 0.9 2.2 2 0 0 2 2 2 0 MMPL family Ribonuc_P_40 PF08584.6 EGO22464.1 - 2.2e-23 82.6 0.0 9.4e-23 80.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit GPI2 PF06432.6 EGO22465.1 - 5.1e-83 278.6 15.7 5.7e-83 278.5 10.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase 7TMR-DISM_7TM PF07695.6 EGO22465.1 - 3.8 7.1 29.0 0.99 9.0 6.5 2.9 1 1 2 3 3 3 0 7TM diverse intracellular signalling Pantoate_ligase PF02569.10 EGO22466.1 - 1.9e-83 279.4 0.0 2.6e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PAP2 PF01569.16 EGO22467.1 - 3.7e-15 55.7 5.2 6.5e-15 54.9 3.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily Polysacc_synt_C PF14667.1 EGO22467.1 - 0.01 15.6 6.8 0.021 14.6 4.7 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain MNHE PF01899.11 EGO22467.1 - 0.03 13.9 0.5 0.03 13.9 0.3 2.1 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit TIM21 PF08294.6 EGO22467.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 TIM21 BCS1_N PF08740.6 EGO22468.1 - 5.4e-24 84.8 1.6 9.3e-24 84.0 1.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGO22468.1 - 5.3e-15 55.7 0.0 2.7e-13 50.2 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO22468.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGO22468.1 - 0.00063 20.5 0.6 0.0014 19.3 0.1 2.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGO22468.1 - 0.0011 17.9 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EGO22468.1 - 0.0072 15.4 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EGO22468.1 - 0.0088 15.4 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGO22468.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGO22468.1 - 0.012 15.5 0.1 0.032 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGO22468.1 - 0.015 15.2 0.1 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGO22468.1 - 0.015 14.8 0.2 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGO22468.1 - 0.017 14.8 0.0 0.074 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGO22468.1 - 0.023 14.3 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EGO22468.1 - 0.03 14.8 0.1 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EGO22468.1 - 0.031 14.4 0.0 0.089 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGO22468.1 - 0.035 14.4 0.0 0.15 12.3 0.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EGO22468.1 - 0.078 13.2 0.2 0.26 11.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGO22468.1 - 0.098 12.1 1.5 0.14 11.6 0.0 2.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EGO22468.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EGO22468.1 - 0.15 12.2 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 1 0 RNA helicase F-box-like PF12937.2 EGO22469.1 - 0.14 11.9 2.1 2.2 8.0 0.1 2.9 2 1 0 2 2 2 0 F-box-like HMG_CoA_synt_C PF08540.5 EGO22470.1 - 6.4e-88 294.8 0.1 9.2e-87 291.1 0.1 2.0 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGO22470.1 - 3e-84 280.8 0.1 4.3e-84 280.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 EGO22470.1 - 0.0025 17.4 0.5 0.0068 16.0 0.1 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EGO22470.1 - 0.011 15.7 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal VMA21 PF09446.5 EGO22473.1 - 2e-10 40.4 5.1 3.2e-10 39.7 3.5 1.3 1 0 0 1 1 1 1 VMA21-like domain Transposase_21 PF02992.9 EGO22475.1 - 2.2e-11 43.3 0.2 1.4e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Transposase family tnp2 DUF4218 PF13960.1 EGO22475.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF3632 PF12311.3 EGO22477.1 - 1.8e-08 34.3 0.1 4e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 EGO22478.1 - 6.6e-05 22.9 0.7 0.0001 22.3 0.5 1.2 1 0 0 1 1 1 1 ribonuclease DUF4354 PF14263.1 EGO22478.1 - 0.068 12.8 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) PD40 PF07676.7 EGO22479.1 - 0.0032 17.1 0.1 0.89 9.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat WD40 PF00400.27 EGO22479.1 - 0.0097 15.7 0.1 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1150 PF06620.6 EGO22479.1 - 0.14 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) WD40 PF00400.27 EGO22480.1 - 3.2 7.7 7.1 6 6.9 0.2 2.5 3 0 0 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.27 EGO22481.1 - 1.1e-06 28.3 20.7 0.0049 16.6 0.3 7.9 8 1 0 8 8 8 2 WD domain, G-beta repeat AAA_16 PF13191.1 EGO22481.1 - 4e-05 23.6 0.0 0.00094 19.2 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGO22481.1 - 0.00064 19.4 0.0 0.0031 17.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGO22481.1 - 0.014 15.4 0.0 0.95 9.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO22481.1 - 0.018 15.8 0.0 0.24 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PQQ_3 PF13570.1 EGO22481.1 - 0.06 13.6 0.3 6.3 7.2 0.1 4.1 5 0 0 5 5 4 0 PQQ-like domain AAA PF00004.24 EGO22481.1 - 0.07 13.3 0.0 0.24 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 EGO22481.1 - 0.081 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EGO22481.1 - 0.12 12.5 0.1 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EGO22481.1 - 0.13 12.1 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO22481.1 - 0.14 11.9 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 EGO22481.1 - 0.33 10.5 0.0 0.79 9.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase SHS2_Rpb7-N PF03876.12 EGO22482.1 - 9.1e-15 54.5 0.0 1.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGO22482.1 - 1.2e-11 44.5 0.8 2.7e-11 43.3 0.5 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EGO22482.1 - 0.0094 16.1 0.1 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 BNR PF02012.15 EGO22483.1 - 8.9e-06 24.7 44.2 0.26 11.2 0.2 11.4 11 0 0 11 11 11 6 BNR/Asp-box repeat PSII_BNR PF14870.1 EGO22483.1 - 0.0048 15.9 3.3 3.2 6.6 0.0 4.3 4 1 1 5 5 5 3 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.10 EGO22483.1 - 0.0087 15.7 0.0 0.23 11.1 0.0 2.7 3 0 0 3 3 3 1 Iron dependent repressor, metal binding and dimerisation domain RNA_pol_Rbc25 PF08292.7 EGO22484.1 - 1e-29 103.1 0.0 1.4e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EGO22484.1 - 1e-17 64.0 0.0 2.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Methyltransf_23 PF13489.1 EGO22485.1 - 3.1e-13 49.7 0.0 5.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO22485.1 - 7.6e-12 45.5 0.0 2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO22485.1 - 5.1e-10 39.7 0.0 1.5e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO22485.1 - 5.6e-10 39.4 0.0 9.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO22485.1 - 8.1e-10 39.2 0.0 2.5e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO22485.1 - 4.5e-08 32.8 0.0 7.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO22485.1 - 0.0069 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGO22485.1 - 0.007 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGO22485.1 - 0.024 13.6 0.0 0.2 10.6 0.0 2.0 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EGO22485.1 - 0.047 12.7 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DUF3419 PF11899.3 EGO22485.1 - 0.048 12.3 0.0 0.063 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 EGO22485.1 - 0.055 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EGO22485.1 - 0.17 11.1 0.0 16 4.6 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 EGO22485.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CNH PF00780.17 EGO22486.1 - 5.7e-63 212.9 0.0 9e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EGO22486.1 - 3.7e-55 186.5 3.1 3.4e-32 111.7 0.1 3.2 2 1 0 2 2 2 2 RhoGEF domain PH_5 PF15405.1 EGO22486.1 - 1.9e-16 60.2 0.0 4.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGO22486.1 - 4.9e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 PH domain DEP PF00610.16 EGO22486.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-CCHC_4 PF14392.1 EGO22486.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle AA_permease PF00324.16 EGO22487.1 - 4.3e-115 384.7 39.2 4.9e-115 384.5 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO22487.1 - 2.6e-33 115.1 42.3 3.4e-33 114.8 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease Adeno_E3B PF03376.9 EGO22487.1 - 0.47 10.4 5.4 7.4 6.5 1.7 2.7 2 0 0 2 2 2 0 Adenovirus E3B protein WD40 PF00400.27 EGO22489.1 - 2.2e-30 103.4 4.1 6.4e-10 38.5 0.1 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO22489.1 - 0.0012 17.0 0.4 0.047 11.8 0.0 2.8 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO22489.1 - 0.017 13.8 0.0 3.2 6.3 0.0 3.1 2 2 1 3 3 3 0 Nup133 N terminal like DUF4123 PF13503.1 EGO22489.1 - 0.055 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Fcf1 PF04900.7 EGO22490.1 - 1.2e-27 95.9 0.0 2.5e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Fcf1 Nucleo_P87 PF07267.6 EGO22490.1 - 0.16 10.6 2.5 0.17 10.5 1.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HTH_Tnp_Tc5 PF03221.11 EGO22493.1 - 1.2e-05 25.0 0.0 3.3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain START PF01852.14 EGO22496.1 - 2.4e-16 59.6 0.1 3.7e-07 29.6 0.0 4.3 4 0 0 4 4 4 3 START domain Phos_pyr_kin PF08543.7 EGO22497.1 - 1.2e-10 40.9 0.0 2.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EGO22497.1 - 2.3e-07 30.2 0.3 8.5e-06 25.0 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Pol_alpha_B_N PF08418.5 EGO22500.1 - 5.8 6.3 6.9 6.4 6.2 4.8 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GST_N_3 PF13417.1 EGO22501.1 - 3.6e-11 43.1 0.0 1e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO22501.1 - 9.5e-10 38.3 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO22501.1 - 2e-06 27.8 0.0 5.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO22501.1 - 0.00028 20.8 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO22501.1 - 0.0033 17.2 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO22501.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribonuclease PF00545.15 EGO22502.1 - 6.6e-05 22.9 0.7 0.0001 22.3 0.5 1.2 1 0 0 1 1 1 1 ribonuclease DUF4354 PF14263.1 EGO22502.1 - 0.028 14.1 0.2 0.042 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) CDC45 PF02724.9 EGO22504.1 - 0.091 10.7 13.5 0.12 10.3 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EGO22504.1 - 0.24 10.9 18.1 0.42 10.1 12.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EGO22504.1 - 0.36 9.8 15.0 0.59 9.1 10.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO22504.1 - 1.6 6.5 16.8 0.96 7.2 9.9 1.7 2 0 0 2 2 2 0 Nop14-like family DUF3527 PF12043.3 EGO22506.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) GST_N_3 PF13417.1 EGO22509.1 - 1.1e-10 41.5 0.0 3.5e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO22509.1 - 1.1e-08 34.8 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO22509.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO22509.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO22509.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Actin PF00022.14 EGO22511.1 - 1.8e-120 402.0 0.0 2.2e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGO22511.1 - 0.00023 19.8 0.0 0.00036 19.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PepSY_TM_1 PF13172.1 EGO22512.1 - 4.9 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix Mito_carr PF00153.22 EGO22514.1 - 5.4e-08 32.4 0.0 0.0017 18.0 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Glycos_transf_2 PF00535.21 EGO22515.1 - 6.2e-19 68.3 0.0 8.1e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGO22515.1 - 8.4e-07 29.0 0.0 8.4e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Toprim_3 PF13362.1 EGO22515.1 - 0.023 14.9 0.0 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 Toprim domain GST_N_3 PF13417.1 EGO22516.1 - 1.4e-12 47.6 0.0 4.2e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO22516.1 - 3.5e-11 42.9 0.0 1.7e-10 40.7 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO22516.1 - 1.2e-06 28.5 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO22516.1 - 0.0016 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO22516.1 - 0.003 17.9 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO22516.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glycos_transf_2 PF00535.21 EGO22517.1 - 2.8e-24 85.6 0.0 3.6e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGO22517.1 - 5.2e-12 46.0 0.0 5.1e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Toprim_3 PF13362.1 EGO22517.1 - 0.0076 16.4 0.0 0.35 11.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Glyco_tranf_2_2 PF10111.4 EGO22517.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Mito_carr PF00153.22 EGO22518.1 - 5.7e-10 38.7 0.0 0.0016 18.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Reoviridae_Vp9 PF08978.5 EGO22520.1 - 0.03 13.2 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 TPR_11 PF13414.1 EGO22521.1 - 1.4e-40 136.7 7.2 2.2e-15 56.0 0.3 5.4 3 2 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 EGO22521.1 - 2.4e-29 99.6 0.0 0.0012 18.3 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGO22521.1 - 7.9e-26 87.8 4.4 0.0068 16.2 0.2 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.26 EGO22521.1 - 1e-22 79.6 0.7 6.6e-22 77.0 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.1 EGO22521.1 - 1e-15 57.4 6.3 1.5e-06 28.0 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGO22521.1 - 1.6e-14 53.5 8.5 5.8e-05 22.8 0.0 5.4 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO22521.1 - 1.1e-13 51.4 12.6 0.0022 18.6 0.3 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGO22521.1 - 3.1e-10 40.2 7.5 0.011 16.1 0.0 5.4 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO22521.1 - 2.9e-08 33.6 13.9 0.39 11.4 0.1 7.2 4 3 3 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO22521.1 - 1.9e-07 31.1 0.8 0.0052 16.8 0.1 4.1 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGO22521.1 - 2e-05 24.4 0.4 2.2 8.6 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO22521.1 - 6.2e-05 22.4 0.0 55 3.8 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO22521.1 - 0.00077 19.0 1.9 16 5.5 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EGO22521.1 - 0.00099 18.2 4.0 2.9 6.8 0.2 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 EGO22521.1 - 0.002 17.9 0.8 0.9 9.4 0.0 3.4 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 EGO22521.1 - 0.0021 17.2 0.2 0.99 8.6 0.0 3.7 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.1 EGO22521.1 - 0.011 16.1 0.3 2.2 8.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2573 PF10835.3 EGO22521.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) TPR_10 PF13374.1 EGO22521.1 - 0.085 12.8 7.3 8.4 6.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO22521.1 - 0.36 10.7 2.6 2.2 8.2 0.1 3.6 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 EGO22522.1 - 1.2e-50 167.6 19.4 1.4e-11 43.8 0.8 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EGO22522.1 - 2.5e-14 52.7 1.1 2.5e-14 52.7 0.8 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGO22522.1 - 3.9e-08 32.7 1.0 9.7e-08 31.4 0.7 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGO22522.1 - 0.00018 19.7 10.6 0.83 7.7 0.1 4.4 2 1 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EGO22522.1 - 0.09 13.0 4.1 21 5.5 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain DUF3613 PF12266.3 EGO22523.1 - 0.059 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) RNA_pol PF00940.14 EGO22523.1 - 0.11 10.8 0.2 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase O-FucT PF10250.4 EGO22524.1 - 1.5e-11 44.0 0.6 0.00014 21.1 0.0 3.2 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase RNase_P_pop3 PF08228.6 EGO22524.1 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 RNase P subunit Pop3 Cu-oxidase PF00394.17 EGO22525.1 - 1.6e-46 158.0 0.0 1.8e-42 144.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO22525.1 - 2.7e-43 146.7 6.1 1.4e-39 134.7 0.1 4.6 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO22525.1 - 1.4e-39 134.5 0.7 2.7e-38 130.3 0.3 2.8 3 0 0 3 3 3 1 Multicopper oxidase DUF4605 PF15378.1 EGO22526.1 - 0.059 13.0 0.6 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) SRF-TF PF00319.13 EGO22527.1 - 3.2e-18 64.6 0.0 6.2e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) dCMP_cyt_deam_1 PF00383.17 EGO22531.1 - 1.6e-17 62.9 0.0 1.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGO22531.1 - 9.1e-11 41.8 0.2 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EGO22531.1 - 0.002 17.5 3.0 0.039 13.3 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ADH_N PF08240.7 EGO22531.1 - 0.015 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DnaJ PF00226.26 EGO22532.1 - 1.2e-10 40.9 0.0 2.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-LSD1 PF06943.7 EGO22533.1 - 4.1 7.0 6.1 5.7 6.6 0.6 2.3 2 0 0 2 2 2 0 LSD1 zinc finger GLTP PF08718.6 EGO22534.1 - 8e-38 129.8 0.0 9.9e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF4451 PF14616.1 EGO22535.1 - 9.2e-10 38.3 8.5 0.084 12.6 0.4 4.3 3 1 1 4 4 4 3 Domain of unknown function (DUF4451) Ecl1 PF12855.2 EGO22535.1 - 0.51 9.6 10.3 0.14 11.4 0.2 3.4 3 0 0 3 3 3 0 Life-span regulatory factor PHD PF00628.24 EGO22535.1 - 1 9.0 4.8 48 3.7 0.0 4.0 4 0 0 4 4 4 0 PHD-finger zf-dskA_traR PF01258.12 EGO22535.1 - 1.7 8.4 4.8 3.9 7.3 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Fungal_trans PF04082.13 EGO22536.1 - 9.9e-24 83.6 0.0 1.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4243 PF14027.1 EGO22537.1 - 4.4e-67 226.8 0.0 2.5e-40 138.9 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4243) Cu-oxidase PF00394.17 EGO22539.1 - 3.5e-52 176.4 0.9 1.9e-48 164.3 0.0 3.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO22539.1 - 1.1e-41 141.2 2.3 2.5e-37 127.2 0.7 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO22539.1 - 4.6e-35 120.1 12.4 1.3e-34 118.6 0.4 3.6 3 1 0 3 3 3 1 Multicopper oxidase Peptidase_M28 PF04389.12 EGO22540.1 - 4.4e-23 81.9 0.1 8.1e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 RRM_1 PF00076.17 EGO22541.1 - 5e-06 26.0 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO22541.1 - 1.2e-05 25.1 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO22541.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1546 PF07571.8 EGO22542.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) VPS28 PF03997.7 EGO22545.1 - 1.3e-59 200.9 0.0 1.5e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DnaJ_CXXCXGXG PF00684.14 EGO22546.1 - 0.011 15.7 5.6 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 DnaJ central domain GCC2_GCC3 PF07699.8 EGO22546.1 - 0.35 10.4 5.0 0.12 11.9 1.1 2.1 2 0 0 2 2 2 0 GCC2 and GCC3 PhzC-PhzF PF02567.11 EGO22548.1 - 6.9e-41 140.3 0.0 8.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Guanylate_kin PF00625.16 EGO22548.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase Methyltransf_15 PF09445.5 EGO22550.1 - 7.5e-38 129.6 0.0 3.9e-28 98.0 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGO22550.1 - 3.6e-09 36.6 0.0 6.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO22550.1 - 3.6e-08 33.9 0.0 6.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO22550.1 - 8e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO22550.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGO22550.1 - 2.9e-05 23.7 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EGO22550.1 - 4.9e-05 23.0 0.0 6.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EGO22550.1 - 6.6e-05 22.3 0.0 9.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EGO22550.1 - 0.0027 18.1 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO22550.1 - 0.033 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 EGO22550.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase tRNA_U5-meth_tr PF05958.6 EGO22550.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RCC1 PF00415.13 EGO22553.1 - 7e-40 135.0 11.4 1.5e-12 47.4 0.1 6.9 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO22553.1 - 9.1e-23 79.3 23.1 2.2e-07 30.3 0.3 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 EGO22553.1 - 2.1e-11 43.3 5.9 2.1e-11 43.3 4.1 2.5 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EGO22553.1 - 0.0031 17.2 3.2 0.0031 17.2 2.2 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EGO22553.1 - 0.026 13.8 4.7 0.035 13.4 0.5 2.7 2 0 0 2 2 2 0 PHD-finger Prim_Zn_Ribbon PF08273.7 EGO22553.1 - 9.6 6.3 9.8 31 4.7 0.0 4.1 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase SQS_PSY PF00494.14 EGO22554.1 - 5.6e-42 143.8 0.0 7.3e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase VQ PF05678.9 EGO22554.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 VQ motif Transgly PF00912.17 EGO22555.1 - 0.0076 15.5 0.2 0.0081 15.4 0.2 1.1 1 0 0 1 1 1 1 Transglycosylase SSF PF00474.12 EGO22556.1 - 3.3e-15 55.6 29.0 6.6e-15 54.6 20.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DAO PF01266.19 EGO22558.1 - 3e-46 157.9 0.8 3.6e-46 157.7 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO22558.1 - 0.00033 20.6 0.5 0.0011 18.9 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO22558.1 - 0.00056 20.0 0.1 0.63 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO22558.1 - 0.0059 16.3 0.2 0.014 15.1 0.1 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGO22558.1 - 0.012 14.7 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EGO22558.1 - 0.014 15.3 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_2 PF07724.9 EGO22559.1 - 9.3e-48 162.3 0.0 1.7e-44 151.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGO22559.1 - 1.2e-20 73.2 3.5 8.5e-20 70.4 0.2 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGO22559.1 - 8e-20 71.3 0.1 1.2e-10 41.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO22559.1 - 4.3e-18 65.3 0.0 1.1e-11 44.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO22559.1 - 1.7e-12 47.7 5.5 1.3e-05 25.2 0.0 4.5 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EGO22559.1 - 9.8e-10 38.6 0.7 0.0031 17.6 0.0 3.6 3 2 1 4 4 2 2 AAA domain IstB_IS21 PF01695.12 EGO22559.1 - 5.1e-08 32.5 0.2 0.039 13.3 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 EGO22559.1 - 6.8e-08 33.3 5.1 0.0046 17.7 0.1 3.9 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGO22559.1 - 9.2e-08 31.7 0.0 2.4e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EGO22559.1 - 4e-07 29.9 0.0 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGO22559.1 - 6.4e-06 25.4 0.1 0.23 10.5 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGO22559.1 - 7.3e-06 26.3 4.7 0.031 14.5 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 EGO22559.1 - 4.2e-05 23.5 0.3 0.19 11.6 0.0 3.5 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGO22559.1 - 4.7e-05 23.1 6.6 0.022 14.4 0.0 4.4 3 2 1 4 4 4 1 Archaeal ATPase AAA_19 PF13245.1 EGO22559.1 - 5.7e-05 22.7 0.0 0.032 13.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EGO22559.1 - 6.6e-05 23.2 0.9 0.074 13.3 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.7 EGO22559.1 - 8.6e-05 21.6 0.5 0.49 9.4 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EGO22559.1 - 0.00025 20.2 0.0 0.019 14.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EGO22559.1 - 0.00032 20.3 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO22559.1 - 0.00044 20.3 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EGO22559.1 - 0.00056 19.6 0.0 0.35 10.5 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGO22559.1 - 0.00078 18.8 0.3 0.34 10.3 0.0 3.5 4 1 0 4 4 3 1 AAA domain DUF258 PF03193.11 EGO22559.1 - 0.002 17.3 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DNA_pol3_delta2 PF13177.1 EGO22559.1 - 0.0025 17.5 0.0 0.021 14.5 0.0 2.4 3 1 0 3 3 2 1 DNA polymerase III, delta subunit NACHT PF05729.7 EGO22559.1 - 0.0027 17.3 0.0 0.5 10.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 EGO22559.1 - 0.0035 16.2 0.0 0.15 10.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGO22559.1 - 0.0036 16.7 0.0 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EGO22559.1 - 0.0042 16.9 0.0 5.7 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain EcoEI_R_C PF08463.5 EGO22559.1 - 0.0043 16.9 4.4 0.0087 15.9 2.4 2.0 2 0 0 2 2 1 1 EcoEI R protein C-terminal DUF342 PF03961.8 EGO22559.1 - 0.017 13.5 0.8 0.034 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NTPase_1 PF03266.10 EGO22559.1 - 0.018 14.7 0.1 4.1 7.0 0.0 3.7 4 0 0 4 4 4 0 NTPase MMR_HSR1 PF01926.18 EGO22559.1 - 0.019 14.9 0.0 3.6 7.5 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_3 PF07726.6 EGO22559.1 - 0.022 14.3 0.0 17 5.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EGO22559.1 - 0.031 14.0 0.3 13 5.5 0.0 3.3 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 EGO22559.1 - 0.049 13.0 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EGO22559.1 - 0.082 12.8 0.4 4.4 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EGO22559.1 - 0.14 12.6 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EGO22559.1 - 0.15 12.4 20.4 0.35 11.1 0.0 3.6 3 1 0 3 3 2 0 AAA domain Bacillus_HBL PF05791.6 EGO22559.1 - 0.28 10.5 2.5 0.54 9.6 1.7 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Spc42p PF11544.3 EGO22559.1 - 0.38 10.7 4.6 0.93 9.4 3.2 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p IncA PF04156.9 EGO22559.1 - 0.41 10.2 13.2 0.78 9.2 9.2 1.4 1 0 0 1 1 1 0 IncA protein AAA_11 PF13086.1 EGO22559.1 - 0.97 8.9 4.0 8.4 5.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain APG6 PF04111.7 EGO22559.1 - 2.3 7.1 8.3 4 6.3 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EGO22559.1 - 4.9 5.9 7.6 8.6 5.2 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RCC1_2 PF13540.1 EGO22561.1 - 1.6e-09 37.1 0.7 2.1e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EGO22561.1 - 3.4e-07 30.3 3.0 0.0071 16.5 0.9 2.6 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat FAD_binding_3 PF01494.14 EGO22562.1 - 8.5e-78 261.8 0.0 1.1e-77 261.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO22562.1 - 3.8e-30 104.6 0.0 8.5e-30 103.5 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EGO22562.1 - 1.9e-06 27.0 0.1 3.8e-06 26.0 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO22562.1 - 2.6e-06 26.2 0.1 3.8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO22562.1 - 3.3e-06 27.0 0.1 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO22562.1 - 5.9e-06 25.3 0.1 1.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGO22562.1 - 2e-05 24.9 0.0 8.1e-05 22.9 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO22562.1 - 6.3e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO22562.1 - 0.0003 20.7 0.1 0.00097 19.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO22562.1 - 0.00041 19.3 0.2 0.00063 18.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EGO22562.1 - 0.00086 18.4 0.3 0.0014 17.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO22562.1 - 0.0013 17.7 0.2 0.027 13.3 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGO22562.1 - 0.0016 18.5 0.1 0.0029 17.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGO22562.1 - 0.0057 16.3 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EGO22562.1 - 0.0065 16.6 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGO22562.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.11 EGO22562.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EGO22562.1 - 0.06 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EGO22562.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EGO22562.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 ThiF family CPSase_L_chain PF00289.17 EGO22562.1 - 0.14 12.2 0.0 23 5.1 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AdoHcyase_NAD PF00670.16 EGO22562.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SE PF08491.5 EGO22562.1 - 0.18 10.6 0.0 0.81 8.4 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase DUF1900 PF08954.6 EGO22563.1 - 9.9e-46 154.6 0.0 4.1e-45 152.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EGO22563.1 - 3.8e-25 87.3 0.1 6.6e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EGO22563.1 - 2.4e-22 77.9 9.3 6.5e-09 35.3 0.0 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat MGC-24 PF05283.6 EGO22563.1 - 0.55 10.0 12.8 0.95 9.2 8.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) GCV_T PF01571.16 EGO22564.1 - 6.5e-67 224.9 0.0 8.3e-67 224.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGO22564.1 - 8.6e-23 80.1 0.3 2.1e-22 78.9 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain ESCRT-II PF05871.7 EGO22565.1 - 4.8e-36 123.7 0.0 1.5e-35 122.0 0.1 1.6 2 0 0 2 2 2 1 ESCRT-II complex subunit DUF1279 PF06916.8 EGO22565.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Glyco_hydro_35 PF01301.14 EGO22566.1 - 2.9e-67 227.2 1.8 1.7e-65 221.4 1.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EGO22566.1 - 4.7e-41 140.1 4.5 9e-41 139.2 3.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EGO22566.1 - 7e-35 119.6 2.5 3.9e-22 78.6 0.8 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EGO22566.1 - 5.1e-17 61.0 0.0 1.3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EGO22566.1 - 0.00087 18.5 0.3 0.003 16.8 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2483 PF10656.4 EGO22568.1 - 0.046 13.7 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) Pkinase PF00069.20 EGO22569.1 - 4.1e-28 98.2 0.0 7.8e-28 97.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22569.1 - 1.8e-08 33.7 0.0 0.0098 14.9 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 EGO22569.1 - 0.00095 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO22569.1 - 0.006 15.5 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGO22569.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DEDD_Tnp_IS110 PF01548.12 EGO22570.1 - 0.058 13.0 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Transposase ODR4-like PF14778.1 EGO22570.1 - 0.063 11.9 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like ArsC PF03960.10 EGO22570.1 - 0.089 12.8 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 ArsC family DUF3939 PF13075.1 EGO22570.1 - 0.093 12.4 0.0 4.8 6.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3939) DUF2543 PF10820.3 EGO22572.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) FAIM1 PF06905.8 EGO22572.1 - 0.091 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) DUF3907 PF13047.1 EGO22572.1 - 0.11 12.0 0.5 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) DDE_Tnp_4 PF13359.1 EGO22573.1 - 2.4e-19 69.5 0.3 3.4e-18 65.7 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Utp12 PF04003.7 EGO22573.1 - 0.09 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Ytp1 PF10355.4 EGO22574.1 - 1.5e-47 162.0 12.9 1.5e-47 162.0 8.9 1.3 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) gag-asp_proteas PF13975.1 EGO22576.1 - 2.2e-07 30.6 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EGO22576.1 - 1.8e-06 27.9 2.2 1.8e-06 27.9 1.5 3.5 5 0 0 5 5 5 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EGO22576.1 - 4.3e-05 23.9 0.0 0.00048 20.5 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease DUF2664 PF10867.3 EGO22576.1 - 0.44 11.1 6.5 1.6 9.4 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2664) Thy1 PF02511.10 EGO22577.1 - 0.033 13.5 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 Thymidylate synthase complementing protein NAD_binding_10 PF13460.1 EGO22578.1 - 0.011 15.8 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding BTB PF00651.26 EGO22579.1 - 7.5e-07 29.1 0.1 1.8e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EGO22580.1 - 3e-11 43.2 0.0 4.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain NMO PF03060.10 EGO22582.1 - 5.3e-67 226.3 1.8 6.2e-67 226.0 1.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO22582.1 - 0.00015 20.7 0.2 0.0017 17.3 0.1 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO22582.1 - 0.043 12.6 3.5 0.067 12.0 2.5 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Filament PF00038.16 EGO22583.1 - 0.0017 17.8 31.4 0.0017 17.8 21.7 1.7 2 0 0 2 2 2 1 Intermediate filament protein CALCOCO1 PF07888.6 EGO22583.1 - 0.0047 15.2 32.3 0.017 13.4 17.2 2.2 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 EGO22583.1 - 0.0053 15.9 12.3 0.0053 15.9 8.6 3.4 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding Metal_resist PF13801.1 EGO22583.1 - 0.024 14.6 1.8 0.024 14.6 1.3 3.2 3 1 1 4 4 3 0 Heavy-metal resistance TSC22 PF01166.13 EGO22583.1 - 0.091 12.7 15.3 3.9 7.4 0.0 5.0 3 2 2 5 5 5 0 TSC-22/dip/bun family Fib_alpha PF08702.5 EGO22583.1 - 0.13 12.3 22.8 1.4 9.0 3.0 4.0 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family IFT57 PF10498.4 EGO22583.1 - 0.3 9.7 25.2 0.72 8.5 17.4 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 EGO22583.1 - 1.8 7.1 33.7 3.4 6.2 7.7 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein CENP-Q PF13094.1 EGO22583.1 - 2.1 8.3 40.8 0.47 10.4 12.8 3.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EGO22583.1 - 4.6 6.7 41.7 4.7 6.7 10.0 3.1 2 1 1 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 EGO22583.1 - 5.4 6.1 13.6 1.7 7.7 2.0 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1515 PF07439.6 EGO22583.1 - 6.3 6.6 15.5 5.9 6.7 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) zf-C3HC4_4 PF15227.1 EGO22584.1 - 7.5e-10 38.5 8.5 1.5e-09 37.5 5.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGO22584.1 - 1.4e-09 37.5 7.8 2.4e-09 36.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO22584.1 - 4e-09 35.9 7.6 7.5e-09 35.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO22584.1 - 1.3e-08 34.6 9.0 2.3e-08 33.9 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO22584.1 - 2.1e-07 30.4 8.8 3.9e-07 29.6 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO22584.1 - 3.1e-06 26.8 7.4 6e-06 25.8 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO22584.1 - 0.00036 20.1 5.9 0.00079 19.0 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EGO22584.1 - 0.1 12.1 4.8 0.25 10.9 3.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EGO22584.1 - 0.25 11.1 3.9 0.54 10.0 2.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF724 PF05266.9 EGO22584.1 - 0.62 9.6 4.7 0.93 9.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Uds1 PF15456.1 EGO22584.1 - 1.6 8.7 8.5 0.54 10.2 3.6 1.8 1 1 1 2 2 2 0 Up-regulated During Septation FYVE PF01363.16 EGO22584.1 - 4.8 7.1 7.3 11 5.9 0.1 2.8 2 1 1 3 3 3 0 FYVE zinc finger BTB PF00651.26 EGO22585.1 - 3.5e-09 36.6 0.0 7.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Rtf2 PF04641.7 EGO22585.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger BTB PF00651.26 EGO22586.1 - 6.7e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SF3a60_bindingd PF12108.3 EGO22587.1 - 0.4 10.2 0.2 0.4 10.2 0.2 1.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain WEMBL PF05701.6 EGO22588.1 - 0.00022 19.8 29.8 0.13 10.7 0.0 2.8 2 1 0 2 2 2 2 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 EGO22588.1 - 0.0009 18.9 38.9 0.0013 18.5 1.4 4.4 3 2 1 4 4 4 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EGO22588.1 - 0.015 14.4 13.4 0.35 10.0 0.6 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EGO22588.1 - 0.017 14.8 28.2 0.22 11.2 0.2 3.7 2 1 0 3 3 3 0 Laminin Domain II APG6 PF04111.7 EGO22588.1 - 0.019 14.0 34.3 0.44 9.5 10.8 3.3 1 1 1 3 3 3 0 Autophagy protein Apg6 DUF904 PF06005.7 EGO22588.1 - 0.023 14.9 1.9 0.023 14.9 1.3 5.7 4 1 2 6 6 6 0 Protein of unknown function (DUF904) GAS PF13851.1 EGO22588.1 - 0.024 13.8 36.6 0.052 12.7 12.8 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding PilJ PF13675.1 EGO22588.1 - 0.068 13.4 23.1 0.28 11.5 0.2 4.4 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc7 PF08317.6 EGO22588.1 - 0.091 11.4 33.5 0.18 10.4 0.2 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Filament PF00038.16 EGO22588.1 - 0.18 11.2 38.4 0.08 12.3 1.7 4.1 2 1 2 4 4 4 0 Intermediate filament protein Pox_A_type_inc PF04508.7 EGO22588.1 - 0.27 11.1 0.0 0.27 11.1 0.0 7.7 8 2 1 9 9 8 0 Viral A-type inclusion protein repeat COG2 PF06148.6 EGO22588.1 - 2.4 8.0 29.2 2.6 7.8 4.3 4.7 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 EGO22588.1 - 2.7 7.8 42.5 0.19 11.5 0.8 3.8 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 EGO22588.1 - 3.1 7.3 46.6 1.4 8.4 3.5 3.7 1 1 2 3 3 3 0 IncA protein Mnd1 PF03962.10 EGO22588.1 - 6 6.4 37.5 1.1 8.8 2.2 4.1 2 1 2 4 4 4 0 Mnd1 family Atg14 PF10186.4 EGO22588.1 - 8.6 5.2 41.8 0.048 12.6 9.4 3.9 2 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 CDP-OH_P_transf PF01066.16 EGO22589.1 - 6.4e-18 64.9 3.1 6.4e-18 64.9 2.1 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RVP_2 PF08284.6 EGO22590.1 - 0.00027 20.8 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO22590.1 - 0.002 18.5 0.0 0.0037 17.7 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO22590.1 - 0.0024 17.6 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease YL1 PF05764.8 EGO22591.1 - 0.005 16.4 9.8 0.0087 15.6 6.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.9 EGO22591.1 - 0.15 10.0 8.7 0.21 9.6 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 EGO22591.1 - 0.18 11.2 12.2 0.31 10.4 8.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2040 PF09745.4 EGO22591.1 - 0.39 10.5 10.5 0.17 11.6 4.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Cwf_Cwc_15 PF04889.7 EGO22591.1 - 1.7 8.3 18.9 2.6 7.7 13.1 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Retrotrans_gag PF03732.12 EGO22592.1 - 0.46 10.5 0.1 0.46 10.5 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein AMP-binding PF00501.23 EGO22594.1 - 1e-23 83.4 0.0 5.5e-22 77.7 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 EGO22594.1 - 0.0055 15.2 0.0 0.0092 14.5 0.0 1.3 1 0 0 1 1 1 1 GH3 auxin-responsive promoter 4HBT_2 PF13279.1 EGO22598.1 - 2.7e-12 47.1 0.0 4.7e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EGO22598.1 - 5e-08 32.9 0.0 8.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EGO22598.1 - 0.064 12.1 0.0 0.63 8.9 0.0 2.0 2 0 0 2 2 2 0 Acyl-ACP thioesterase CAP_GLY PF01302.20 EGO22599.1 - 1.5e-24 85.4 0.4 2.4e-24 84.7 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EGO22599.1 - 6e-23 80.9 0.0 9.3e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EGO22599.1 - 0.033 13.5 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family AAA PF00004.24 EGO22600.1 - 2.5e-96 318.9 0.0 9.8e-47 158.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGO22600.1 - 5.7e-21 74.2 0.5 6.3e-20 70.9 0.3 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EGO22600.1 - 1.5e-13 50.3 0.0 1.9e-05 23.8 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGO22600.1 - 2.9e-13 50.0 0.0 1.3e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGO22600.1 - 7.1e-13 48.6 0.0 1.2e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGO22600.1 - 3e-12 46.4 0.2 7.6e-06 25.7 0.1 4.0 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGO22600.1 - 3.3e-12 47.3 0.0 0.00016 22.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGO22600.1 - 2.6e-11 43.7 0.1 0.0018 18.4 0.0 4.2 3 2 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 EGO22600.1 - 8.2e-11 41.3 0.0 1.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 EGO22600.1 - 1.4e-09 38.2 0.0 0.0031 17.5 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EGO22600.1 - 2.5e-09 36.3 0.1 0.0012 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EGO22600.1 - 4e-08 32.8 0.0 0.0043 16.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO22600.1 - 8.3e-08 31.5 0.1 0.0093 15.0 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_25 PF13481.1 EGO22600.1 - 1.1e-07 31.4 2.5 0.02 14.2 0.0 3.6 2 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EGO22600.1 - 1.4e-07 31.4 0.0 0.0075 16.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGO22600.1 - 2.7e-07 30.2 1.3 0.0093 15.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EGO22600.1 - 3.7e-07 29.5 0.4 0.024 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 EGO22600.1 - 5.4e-07 29.4 0.2 5.8e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 EGO22600.1 - 1.3e-06 28.4 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGO22600.1 - 1.6e-06 28.4 0.2 0.033 14.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain KaiC PF06745.8 EGO22600.1 - 3e-06 26.5 0.6 0.75 8.8 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EGO22600.1 - 5.6e-06 26.4 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EGO22600.1 - 8.5e-06 25.7 0.0 0.0052 16.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EGO22600.1 - 9.6e-06 24.6 0.1 0.009 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EGO22600.1 - 2.3e-05 23.9 0.0 0.45 9.9 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EGO22600.1 - 3.2e-05 23.6 0.1 0.098 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EGO22600.1 - 3.3e-05 24.1 0.0 0.19 12.0 0.0 3.5 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 EGO22600.1 - 5.6e-05 22.4 0.2 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EGO22600.1 - 6.3e-05 23.0 0.0 0.33 11.0 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EGO22600.1 - 8.6e-05 21.5 0.0 0.027 13.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EGO22600.1 - 0.0001 21.9 0.0 0.67 9.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EGO22600.1 - 0.0001 22.0 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein Arch_ATPase PF01637.13 EGO22600.1 - 0.00011 21.9 0.0 3 7.4 0.0 3.7 3 1 1 4 4 3 0 Archaeal ATPase AAA_3 PF07726.6 EGO22600.1 - 0.0002 20.9 0.0 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGO22600.1 - 0.00059 19.5 0.1 0.68 9.5 0.0 3.4 4 0 0 4 4 3 1 NACHT domain Viral_helicase1 PF01443.13 EGO22600.1 - 0.00068 19.2 0.0 0.23 10.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EGO22600.1 - 0.0008 18.4 0.0 0.4 9.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGO22600.1 - 0.0012 18.4 0.0 1.5 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGO22600.1 - 0.0019 17.1 0.0 0.12 11.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 EGO22600.1 - 0.0049 15.7 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EGO22600.1 - 0.0059 16.3 0.3 1.9 8.1 0.0 3.4 3 0 0 3 3 3 1 NTPase KAP_NTPase PF07693.9 EGO22600.1 - 0.024 13.6 0.0 0.6 9.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain UFD1 PF03152.9 EGO22600.1 - 0.029 13.4 0.0 0.09 11.9 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.11 EGO22600.1 - 0.031 13.4 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase ATP-synt_ab PF00006.20 EGO22600.1 - 0.037 13.5 0.1 3.6 7.0 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EGO22600.1 - 0.044 13.4 0.1 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EGO22600.1 - 0.048 13.0 1.4 7.1 5.9 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 EGO22600.1 - 0.051 13.4 1.1 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase Molydop_binding PF01568.16 EGO22600.1 - 0.061 13.1 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain KTI12 PF08433.5 EGO22600.1 - 0.093 11.9 0.0 12 5.0 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EGO22600.1 - 0.19 11.1 0.1 26 4.1 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DAGAT PF03982.8 EGO22601.1 - 1.5e-98 329.1 0.0 2e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EGO22601.1 - 0.097 12.2 3.3 0.057 13.0 0.7 1.7 2 0 0 2 2 2 0 Rer1 family TFIIE-A_C-term PF11521.3 EGO22601.1 - 0.21 11.5 1.0 12 5.8 0.1 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Lipase_3 PF01764.20 EGO22602.1 - 3.1e-21 75.4 0.0 4.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGO22602.1 - 0.0064 16.4 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SFTA2 PF15210.1 EGO22602.1 - 0.051 13.1 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Surfactant-associated protein 2 Cellulase PF00150.13 EGO22603.1 - 4.6e-13 48.9 2.0 1.5e-12 47.3 1.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ytp1 PF10355.4 EGO22604.1 - 3.6e-66 223.1 11.3 3.6e-66 223.1 7.8 2.6 2 1 1 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGO22604.1 - 2.4e-25 88.1 0.6 2.4e-25 88.1 0.4 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF2427) MMgT PF10270.4 EGO22604.1 - 0.0081 16.5 1.4 0.024 15.0 0.2 2.3 2 0 0 2 2 2 1 Membrane magnesium transporter DUF4225 PF13988.1 EGO22604.1 - 1.3 8.4 3.7 0.29 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Ytp1 PF10355.4 EGO22606.1 - 1.3e-66 224.6 10.0 1.3e-66 224.6 6.9 2.7 2 1 1 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGO22606.1 - 2.6e-25 88.0 0.6 2.6e-25 88.0 0.4 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF2427) MMgT PF10270.4 EGO22606.1 - 0.0052 17.2 1.0 0.026 14.9 0.2 2.4 2 0 0 2 2 2 1 Membrane magnesium transporter DUF4225 PF13988.1 EGO22606.1 - 0.12 11.8 0.9 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) NAD_binding_10 PF13460.1 EGO22607.1 - 3.9e-07 30.2 0.1 6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO22607.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF2892 PF11127.3 EGO22607.1 - 0.24 11.2 1.4 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) NAD_binding_10 PF13460.1 EGO22608.1 - 7.4e-08 32.6 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO22608.1 - 5.1e-05 22.8 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EGO22608.1 - 0.007 16.6 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EGO22608.1 - 0.12 11.2 0.0 1.1 8.0 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein RNA_pol_3_Rpc31 PF11705.3 EGO22609.1 - 0.42 10.5 4.4 0.8 9.5 3.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 APG6 PF04111.7 EGO22609.1 - 5.3 5.9 9.3 0.56 9.2 3.3 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 UBX PF00789.15 EGO22611.1 - 5.8e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EGO22611.1 - 0.00034 20.3 1.5 0.0061 16.3 0.0 3.2 3 0 0 3 3 3 1 UBA/TS-N domain Rtf2 PF04641.7 EGO22611.1 - 0.03 13.5 19.4 0.043 13.0 13.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_2 PF12756.2 EGO22611.1 - 0.17 12.0 2.2 0.22 11.6 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CompInhib_SCIN PF11546.3 EGO22611.1 - 0.39 10.5 13.3 0.033 14.0 3.7 2.3 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN DUF4544 PF15077.1 EGO22612.1 - 0.075 12.5 1.2 0.14 11.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) zf-C2H2_4 PF13894.1 EGO22613.1 - 0.0026 17.9 6.4 0.017 15.4 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO22613.1 - 0.0046 17.2 0.7 0.0046 17.2 0.5 2.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type Pkinase PF00069.20 EGO22614.1 - 9.1e-08 31.5 0.0 1.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO22614.1 - 0.0018 18.0 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO22614.1 - 0.033 13.2 0.1 0.064 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_H2_suC PF08615.6 EGO22616.1 - 4.5e-23 81.5 0.0 5.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) COesterase PF00135.23 EGO22617.1 - 9e-64 216.0 0.0 1.3e-63 215.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO22617.1 - 2.9e-08 33.5 0.0 6.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.16 EGO22618.1 - 1.2e-18 66.9 0.0 2.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EGO22618.1 - 0.0041 16.5 0.1 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) AA_permease_2 PF13520.1 EGO22619.1 - 3.2e-52 177.5 56.3 3.7e-52 177.2 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO22619.1 - 5.9e-15 54.5 50.1 7.9e-15 54.1 34.5 1.3 1 1 0 1 1 1 1 Amino acid permease Patatin PF01734.17 EGO22619.1 - 0.041 13.8 0.6 0.065 13.1 0.4 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase Arginase PF00491.16 EGO22620.1 - 2.9e-85 285.9 0.0 3.6e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGO22620.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.13 EGO22621.1 - 5.9e-34 117.0 20.4 1.9e-27 95.8 6.1 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EGO22621.1 - 0.00017 21.3 25.3 0.00039 20.2 3.0 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain WLM PF08325.5 EGO22622.1 - 1.2e-37 129.5 0.0 2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 EGO22622.1 - 4.1e-09 35.7 0.1 7.6e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGO22622.1 - 0.0035 17.5 0.1 0.0092 16.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Peptidase_MA_2 PF13485.1 EGO22622.1 - 0.0068 16.4 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF45 PF01863.12 EGO22622.1 - 0.026 14.3 0.7 0.082 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 Ran_BP1 PF00638.13 EGO22623.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain DNA_pol_delta_4 PF04081.8 EGO22626.1 - 4.3e-21 75.4 0.2 9.7e-21 74.3 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Macoilin PF09726.4 EGO22626.1 - 5.8 5.0 7.1 6.5 4.9 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FAD_binding_3 PF01494.14 EGO22628.1 - 2.2e-79 267.1 0.0 3.5e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO22628.1 - 4.1e-30 104.6 0.0 6.3e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EGO22628.1 - 3.1e-07 29.2 0.9 4.8e-07 28.6 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EGO22628.1 - 7.9e-07 28.2 1.0 1.3e-06 27.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO22628.1 - 9.2e-06 24.7 0.1 1.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO22628.1 - 1.2e-05 24.5 0.2 2.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO22628.1 - 1.3e-05 25.1 0.2 3e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO22628.1 - 1.4e-05 25.0 0.1 1.4e-05 25.0 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO22628.1 - 5.5e-05 22.4 0.5 8.5e-05 21.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO22628.1 - 5.8e-05 23.4 0.1 0.00012 22.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO22628.1 - 0.00019 20.2 0.1 0.00028 19.6 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 EGO22628.1 - 0.00027 19.9 1.1 0.00047 19.1 0.8 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGO22628.1 - 0.00037 19.5 1.8 0.00046 19.2 0.7 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EGO22628.1 - 0.00039 20.0 0.2 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EGO22628.1 - 0.0034 17.0 0.2 0.0078 15.8 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EGO22628.1 - 0.0035 17.4 0.2 0.0058 16.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO22628.1 - 0.0035 17.1 0.1 0.0066 16.2 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 EGO22628.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase TrkA_N PF02254.13 EGO22628.1 - 0.0099 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EGO22628.1 - 0.017 14.6 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGO22628.1 - 0.023 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 EGO22628.1 - 0.039 14.1 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2199 PF09965.4 EGO22628.1 - 0.058 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) XdhC_C PF13478.1 EGO22628.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain APH PF01636.18 EGO22629.1 - 7.3e-08 32.4 0.0 1.5e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGO22629.1 - 0.00047 18.9 0.0 0.00063 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGO22629.1 - 0.0052 15.9 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase FAD_binding_3 PF01494.14 EGO22631.1 - 2.7e-88 296.3 0.0 4.9e-88 295.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO22631.1 - 2.9e-35 121.3 0.0 5.2e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EGO22631.1 - 1.1e-06 27.4 1.0 1.6e-06 26.8 0.3 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO22631.1 - 6.7e-06 26.0 0.1 1.9e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO22631.1 - 8.5e-06 24.8 1.7 1.4e-05 24.1 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO22631.1 - 1.1e-05 24.5 0.1 2.8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO22631.1 - 9.3e-05 22.3 0.2 0.00021 21.2 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO22631.1 - 0.00015 20.9 0.1 0.00032 19.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGO22631.1 - 0.00023 20.1 1.0 0.00055 18.9 0.7 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EGO22631.1 - 0.00033 19.8 0.1 0.00048 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO22631.1 - 0.00043 20.6 0.0 0.0014 18.9 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGO22631.1 - 0.001 18.7 0.4 0.0028 17.3 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EGO22631.1 - 0.0011 17.8 0.9 0.0021 17.0 0.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGO22631.1 - 0.0031 17.6 0.1 0.0067 16.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGO22631.1 - 0.0044 16.4 0.1 0.0086 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CPSase_L_chain PF00289.17 EGO22631.1 - 0.0046 17.0 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 EGO22631.1 - 0.0059 16.5 0.0 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain XdhC_C PF13478.1 EGO22631.1 - 0.0062 16.8 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_9 PF13454.1 EGO22631.1 - 0.0066 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 EGO22631.1 - 0.007 16.3 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Trp_halogenase PF04820.9 EGO22631.1 - 0.0073 14.9 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase SE PF08491.5 EGO22631.1 - 0.017 13.9 0.0 0.06 12.1 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EGO22631.1 - 0.03 13.9 0.2 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EGO22631.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EGO22631.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EGO22631.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UCH PF00443.24 EGO22632.1 - 1.6e-73 247.1 0.0 2.3e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO22632.1 - 1.9e-23 83.3 0.0 4e-23 82.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-HC5HC2H_2 PF13832.1 EGO22633.1 - 3.1e-20 72.1 21.5 3.2e-19 68.9 2.7 4.3 2 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGO22633.1 - 3.4e-14 52.7 1.2 3.4e-14 52.7 0.8 4.7 3 2 1 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 EGO22633.1 - 3.2e-12 45.9 58.2 7.3e-08 31.9 6.4 6.6 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 EGO22633.1 - 3e-11 43.1 0.0 7.8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 EGO22633.1 - 0.0046 16.2 35.1 0.0062 15.8 2.8 5.9 5 0 0 5 5 5 3 PHD-finger C1_1 PF00130.17 EGO22633.1 - 0.0074 15.9 1.8 0.0074 15.9 1.2 6.1 5 2 2 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.14 EGO22633.1 - 0.07 12.8 4.6 0.27 11.0 3.2 2.1 1 0 0 1 1 1 0 AT hook motif HATPase_c PF02518.21 EGO22634.1 - 2.3e-24 85.2 0.0 4.6e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO22634.1 - 1.5e-17 63.5 0.5 7.6e-17 61.3 0.1 2.3 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c_2 PF13581.1 EGO22634.1 - 0.045 13.5 0.6 2.7 7.7 0.7 2.8 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EGO22634.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ran_BP1 PF00638.13 EGO22635.1 - 9.8e-10 38.5 1.2 5e-09 36.2 0.8 2.0 1 1 0 1 1 1 1 RanBP1 domain PBP-Tp47_a PF14889.1 EGO22635.1 - 0.099 11.9 1.1 0.23 10.7 0.8 1.5 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Ribosomal_L5_C PF00673.16 EGO22636.1 - 4.3e-22 77.6 0.0 6.1e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGO22636.1 - 2.1e-13 49.8 0.1 6.7e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 SNF2_N PF00176.18 EGO22640.1 - 2.3e-11 43.0 0.3 4.1e-11 42.2 0.2 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGO22640.1 - 0.00099 18.9 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DKNYY PF13644.1 EGO22643.1 - 0.045 14.0 1.1 0.048 13.9 0.8 1.1 1 0 0 1 1 1 0 DKNYY family zf-C2H2 PF00096.21 EGO22647.1 - 0.0074 16.5 0.1 0.016 15.5 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO22647.1 - 0.03 14.6 0.1 0.081 13.2 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGO22649.1 - 0.2 11.9 4.6 0.2 11.9 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EGO22649.1 - 5.8 7.4 6.0 0.46 10.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4381 PF14316.1 EGO22651.1 - 0.051 13.6 0.2 0.057 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) APC2 PF08672.6 EGO22654.1 - 0.00063 19.9 9.2 0.18 12.1 0.1 5.9 4 2 3 7 7 7 3 Anaphase promoting complex (APC) subunit 2 AbbA_antirepres PF14156.1 EGO22656.1 - 0.17 11.5 1.3 0.52 10.0 0.0 2.4 3 0 0 3 3 3 0 Antirepressor AbbA DUF3653 PF12375.3 EGO22657.1 - 0.088 13.0 1.7 9.7 6.4 0.2 2.8 2 1 0 2 2 2 0 Phage protein DUF2951 PF11166.3 EGO22657.1 - 0.15 11.9 1.9 0.64 9.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Catalase PF00199.14 EGO22658.1 - 1.4e-146 488.1 0.2 1.8e-146 487.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGO22658.1 - 3.7e-12 45.9 0.0 9.1e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Thioredoxin PF00085.15 EGO22659.1 - 8.3e-23 80.0 0.0 1.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGO22659.1 - 0.00025 21.1 0.1 0.00072 19.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGO22659.1 - 0.00041 20.3 0.1 0.0031 17.5 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGO22659.1 - 0.0012 18.8 0.1 0.0065 16.4 0.1 2.2 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EGO22659.1 - 0.0019 17.8 0.0 0.0091 15.6 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EGO22659.1 - 0.022 14.3 0.1 0.2 11.1 0.0 2.2 2 1 1 3 3 3 0 Redoxin Thioredoxin_9 PF14595.1 EGO22659.1 - 0.035 13.6 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin STT3 PF02516.9 EGO22660.1 - 1.1e-135 453.3 38.8 2.3e-133 445.6 26.9 2.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 EGO22660.1 - 0.0064 16.3 13.0 0.0064 16.3 9.0 3.6 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase p450 PF00067.17 EGO22661.1 - 3.7e-33 114.7 0.1 6.3e-33 113.9 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.14 EGO22665.1 - 4.4e-07 29.2 0.2 9.4e-07 28.1 0.1 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease PCDO_beta_N PF12391.3 EGO22665.1 - 0.27 10.6 3.5 0.27 10.6 0.0 2.6 3 0 0 3 3 3 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Tub_2 PF04525.7 EGO22666.1 - 0.0063 15.9 0.0 0.0079 15.5 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 Mt_ATP-synt_B PF05405.9 EGO22668.1 - 1.4e-44 151.4 9.8 1.8e-44 151.0 6.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_E_2 PF08112.6 EGO22668.1 - 0.011 15.8 1.0 0.29 11.2 0.4 2.3 2 0 0 2 2 2 0 ATP synthase epsilon subunit Viral_Hsp90 PF03225.9 EGO22668.1 - 0.023 13.0 0.5 0.033 12.4 0.4 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Dynamin_M PF01031.15 EGO22669.1 - 1.9e-112 374.8 0.0 3.5e-112 374.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGO22669.1 - 2.5e-53 180.3 0.0 4.7e-53 179.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGO22669.1 - 6.3e-30 102.9 1.6 1.8e-29 101.4 0.5 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_16 PF13191.1 EGO22669.1 - 0.0013 18.7 0.0 0.0053 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EGO22669.1 - 0.0055 16.6 0.0 0.027 14.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Baculo_p74 PF04583.7 EGO22669.1 - 0.028 13.6 0.2 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Baculoviridae p74 conserved region Miro PF08477.8 EGO22669.1 - 0.046 14.2 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein ABC_tran PF00005.22 EGO22669.1 - 0.086 13.1 0.1 7.2 6.9 0.0 3.2 3 1 0 3 3 3 0 ABC transporter AIG1 PF04548.11 EGO22669.1 - 0.1 11.6 0.0 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 AIG1 family SYS1 PF09801.4 EGO22670.1 - 2e-28 99.1 7.3 3.9e-21 75.5 2.9 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network MORN PF02493.15 EGO22670.1 - 0.052 13.2 1.5 0.17 11.6 0.9 1.9 1 1 0 1 1 1 0 MORN repeat DPPIV_N PF00930.16 EGO22671.1 - 1e-90 303.9 1.9 1.2e-90 303.6 0.1 1.9 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGO22671.1 - 1.1e-45 155.4 0.8 2.2e-45 154.4 0.5 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO22671.1 - 3.3e-07 30.1 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO22671.1 - 2.6e-06 27.5 0.1 2.5e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGO22671.1 - 3.9e-05 23.2 3.1 0.00012 21.6 2.2 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EGO22671.1 - 0.036 12.5 0.1 0.3 9.5 0.1 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EGO22671.1 - 0.072 12.5 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mito_carr PF00153.22 EGO22673.1 - 1.3e-57 191.5 5.0 7.9e-21 73.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EGO22676.1 - 6e-23 81.3 0.0 1.7e-20 73.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO22676.1 - 4.2e-06 26.0 0.0 9.4e-06 24.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO22676.1 - 0.0029 17.3 0.2 0.0047 16.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO22676.1 - 0.017 14.6 0.2 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CMD PF02627.15 EGO22677.1 - 0.00012 21.8 0.0 0.00075 19.2 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cofilin_ADF PF00241.15 EGO22678.1 - 5.1e-16 58.7 0.0 6.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.4 EGO22678.1 - 0.08 12.6 0.2 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Cu-oxidase PF00394.17 EGO22679.1 - 7.4e-46 155.9 0.0 1.4e-41 142.0 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO22679.1 - 6.7e-38 129.0 2.2 1.4e-35 121.6 0.2 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO22679.1 - 8.5e-37 125.7 6.3 1.4e-34 118.5 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Pilin_PilA PF14245.1 EGO22679.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Type IV pilin PilA PAT1 PF09770.4 EGO22680.1 - 2.5e-154 515.5 28.0 3.5e-154 515.1 19.4 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ribosomal_L28e PF01778.12 EGO22681.1 - 3e-30 105.0 1.3 3e-30 105.0 0.9 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EGO22681.1 - 6.1e-18 64.7 31.9 6.7e-18 64.6 16.5 2.9 2 1 0 2 2 2 1 Mak16 protein C-terminal region Nop14 PF04147.7 EGO22681.1 - 0.24 9.3 15.9 0.27 9.0 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 EGO22681.1 - 3.6 7.3 12.2 5.4 6.8 8.4 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1604 PF07713.8 EGO22682.1 - 4.8e-37 125.6 0.7 4.8e-37 125.6 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EGO22682.1 - 1.9e-05 24.3 5.3 2.1e-05 24.1 0.2 2.7 2 0 0 2 2 2 1 G-patch domain Amidase PF01425.16 EGO22683.1 - 1.8e-109 366.5 0.3 6.4e-109 364.7 0.2 1.8 1 1 1 2 2 2 1 Amidase Mito_carr PF00153.22 EGO22684.1 - 1.1e-65 217.4 2.1 2e-22 78.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.10 EGO22684.1 - 0.063 12.8 1.2 2.7 7.5 0.1 3.4 3 1 0 3 3 3 0 Chromate transporter DUF4218 PF13960.1 EGO22686.1 - 3.9e-05 23.0 0.0 9.7e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PPDK_N PF01326.14 EGO22686.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Retrotrans_gag PF03732.12 EGO22690.1 - 8.6e-08 32.1 5.8 1e-07 31.8 0.1 3.0 2 1 1 3 3 3 1 Retrotransposon gag protein Retrotrans_gag PF03732.12 EGO22691.1 - 1.6e-06 28.0 1.4 1.6e-06 28.0 1.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO22691.1 - 8.1e-05 22.3 5.1 0.00022 20.9 3.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO22691.1 - 0.012 15.3 8.0 0.012 15.3 5.5 2.3 2 1 0 2 2 2 0 Zinc knuckle Herpes_UL55 PF04537.7 EGO22691.1 - 0.037 13.4 1.1 0.082 12.2 0.6 1.6 2 0 0 2 2 2 0 Herpesvirus UL55 protein DUF4139 PF13598.1 EGO22692.1 - 0.062 12.5 2.5 0.077 12.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4139) Ribonuclease PF00545.15 EGO22693.1 - 1.8e-06 27.8 0.3 2.6e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 ribonuclease DEPP PF15343.1 EGO22693.1 - 0.0056 16.3 0.1 0.0079 15.8 0.1 1.1 1 0 0 1 1 1 1 Decidual protein induced by progesterone family Gpi16 PF04113.9 EGO22695.1 - 6.4e-141 470.1 0.1 8e-139 463.2 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component F-box-like PF12937.2 EGO22696.1 - 0.0047 16.6 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like RIIa PF02197.12 EGO22696.1 - 0.029 13.8 0.1 0.28 10.6 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit E3_binding PF02817.12 EGO22697.1 - 0.086 12.4 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 e3 binding domain 3-HAO PF06052.7 EGO22698.1 - 5.5e-58 194.6 0.0 6.2e-58 194.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EGO22698.1 - 7.3e-06 25.3 0.8 1e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 EGO22698.1 - 0.054 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Baculo_PEP_C PF04513.7 EGO22700.1 - 0.026 14.3 11.7 0.067 13.0 8.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc97_Spc98 PF04130.8 EGO22700.1 - 0.027 12.7 0.6 0.032 12.5 0.4 1.1 1 0 0 1 1 1 0 Spc97 / Spc98 family FlgN PF05130.7 EGO22700.1 - 0.04 14.1 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 FlgN protein NIT PF08376.5 EGO22700.1 - 0.091 12.2 0.8 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Nitrate and nitrite sensing EF-hand_2 PF09068.6 EGO22700.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.6 1 1 0 1 1 1 0 EF hand GFO_IDH_MocA PF01408.17 EGO22701.1 - 7.9e-12 45.7 0.2 3e-11 43.8 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO22701.1 - 0.0025 17.5 0.1 0.031 14.0 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 EGO22701.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Mpv17_PMP22 PF04117.7 EGO22702.1 - 1.9e-24 85.0 0.6 3.5e-24 84.1 0.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family adh_short PF00106.20 EGO22703.1 - 1.5e-26 93.3 0.2 2.4e-26 92.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO22703.1 - 1.1e-13 51.4 0.0 1.7e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO22703.1 - 2.9e-09 36.8 0.0 5.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO22703.1 - 8e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO22703.1 - 1.9e-06 28.0 0.4 3.8e-06 27.0 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EGO22703.1 - 0.026 14.9 0.0 0.095 13.1 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EGO22703.1 - 0.031 14.0 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EGO22703.1 - 0.035 13.3 0.1 0.066 12.4 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family DUF2066 PF09839.4 EGO22703.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) RmlD_sub_bind PF04321.12 EGO22703.1 - 0.088 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DDE_1 PF03184.14 EGO22705.1 - 2.9e-27 95.2 0.0 3.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EGO22705.1 - 0.027 14.2 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 EGO22708.1 - 1.2e-06 27.9 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGO22708.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short PF00106.20 EGO22709.1 - 2.2e-27 96.0 0.0 3.1e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO22709.1 - 3.8e-14 53.0 0.0 5.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO22709.1 - 3.6e-10 39.7 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO22709.1 - 4.3e-08 32.8 0.0 5.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO22709.1 - 4.4e-07 30.0 0.4 9.7e-07 28.9 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO22709.1 - 0.02 14.1 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 EGO22709.1 - 0.023 15.1 0.0 0.087 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EGO22709.1 - 0.028 14.1 0.1 0.61 9.9 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EGO22709.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO22710.1 - 8.4e-05 22.6 0.1 0.0016 18.4 0.1 2.6 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO22710.1 - 0.00017 20.6 0.4 0.0028 16.6 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 EGO22710.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EGO22710.1 - 0.022 14.1 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gemini_AC4_5 PF04807.7 EGO22710.1 - 0.19 11.2 0.6 0.35 10.3 0.4 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region adh_short_C2 PF13561.1 EGO22712.1 - 6e-33 114.5 0.0 7.6e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO22712.1 - 1.2e-20 74.1 0.5 1.6e-20 73.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO22712.1 - 1.9e-09 37.4 0.1 2.8e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.16 EGO22712.1 - 0.0032 16.7 0.2 0.012 14.9 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein PA PF02225.17 EGO22712.1 - 0.0059 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 PA domain Saccharop_dh PF03435.13 EGO22712.1 - 0.018 14.0 0.0 0.045 12.7 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Flavodoxin_4 PF12682.2 EGO22712.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin ThiF PF00899.16 EGO22714.1 - 1e-39 135.4 0.0 1.8e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EGO22714.1 - 3.1e-28 97.1 0.1 6.2e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGO22714.1 - 1.2e-18 66.2 2.2 1.2e-18 66.2 1.5 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EGO22714.1 - 1.5e-06 28.1 0.0 3.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EGO22714.1 - 0.0029 17.8 0.0 0.0097 16.1 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Cut8_N PF14482.1 EGO22714.1 - 0.43 10.6 4.3 0.79 9.7 1.5 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Glyco_hydro_71 PF03659.9 EGO22715.1 - 1.1e-89 300.6 9.6 8e-85 284.6 6.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 NAD_binding_6 PF08030.7 EGO22716.1 - 4.1e-05 23.5 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Pyridox_oxidase PF01243.15 EGO22716.1 - 8e-05 22.5 0.0 0.0097 15.8 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 EGO22716.1 - 0.039 14.5 0.0 0.14 12.7 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GST_N_3 PF13417.1 EGO22717.1 - 3.7e-11 43.0 0.0 6.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO22717.1 - 3.7e-09 36.3 0.1 7.7e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO22717.1 - 6.8e-07 29.6 0.0 3.1e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO22717.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO22717.1 - 0.00066 19.6 0.0 0.00097 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 EGO22717.1 - 0.00093 18.7 0.0 0.002 17.7 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin 2, C terminal domain GST_N_2 PF13409.1 EGO22717.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YqcI_YcgG PF08892.6 EGO22718.1 - 1.4e-61 207.8 0.0 1.6e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 YqcI/YcgG family Catalase PF00199.14 EGO22719.1 - 2.1e-147 490.8 0.1 2.5e-147 490.5 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGO22719.1 - 3.9e-12 45.8 0.0 1.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive CPL PF08144.6 EGO22720.1 - 1.1e-21 77.1 0.0 7.2e-19 68.0 0.0 3.5 3 1 1 4 4 4 2 CPL (NUC119) domain Dimer_Tnp_Tn5 PF02281.11 EGO22720.1 - 0.077 13.1 0.1 0.75 9.9 0.0 2.4 2 1 0 2 2 2 0 Transposase Tn5 dimerisation domain FAM195 PF14799.1 EGO22720.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 FAM195 family PepSY_TM_1 PF13172.1 EGO22721.1 - 5 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix SNAPc19 PF15497.1 EGO22722.1 - 0.1 12.7 0.7 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 PAD_porph PF04371.10 EGO22724.1 - 0.0039 16.2 0.0 0.0043 16.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Protamine_3 PF08188.6 EGO22725.1 - 0.023 14.6 0.2 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Spermatozal protamine family Methyltransf_2 PF00891.13 EGO22728.1 - 4.2e-29 101.4 0.0 7.2e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGO22728.1 - 1.9e-06 28.4 0.0 7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO22728.1 - 0.005 16.5 0.0 0.025 14.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO22728.1 - 0.057 12.7 0.0 0.18 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.14 EGO22730.1 - 4.3e-45 154.1 0.0 6.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO22730.1 - 3.9e-27 95.2 0.0 9.3e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ish1 PF10281.4 EGO22730.1 - 0.12 12.4 0.2 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Sld5 PF05916.6 EGO22732.1 - 0.00019 21.7 0.0 0.00037 20.7 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein ICAT PF06384.6 EGO22732.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Plectin PF00681.15 EGO22732.1 - 0.13 11.8 0.1 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat ThiF PF00899.16 EGO22733.1 - 3.6e-07 30.0 0.0 5.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family SPX PF03105.14 EGO22734.1 - 3e-21 76.4 0.0 2.1e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EGO22734.1 - 1.8e-07 30.9 7.7 3.4e-07 30.0 5.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EGO22734.1 - 2.5e-07 30.2 7.9 4.5e-07 29.4 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO22734.1 - 3.1e-07 29.9 5.9 4.7e-07 29.3 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO22734.1 - 3.5e-07 30.1 9.5 6e-07 29.3 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO22734.1 - 2.5e-06 27.2 7.4 4.6e-06 26.3 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGO22734.1 - 4.7e-05 23.0 7.5 8.9e-05 22.1 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGO22734.1 - 0.00041 19.8 2.9 0.00091 18.7 2.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGO22734.1 - 0.0048 16.5 8.1 0.015 15.0 5.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EGO22734.1 - 0.0088 15.8 3.4 0.018 14.8 2.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGO22734.1 - 0.054 13.6 5.0 0.13 12.3 3.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EGO22734.1 - 0.092 12.5 1.1 0.17 11.7 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGO22734.1 - 0.18 11.3 6.6 0.74 9.4 4.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EGO22734.1 - 1.2 8.6 6.2 2.4 7.7 4.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RF-1 PF00472.15 EGO22735.1 - 6.5e-38 129.0 2.5 1.1e-37 128.2 1.7 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGO22735.1 - 1.6e-27 95.5 0.0 3.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 PCRF domain DUF2534 PF10749.4 EGO22736.1 - 0.0036 17.1 3.9 0.0066 16.3 2.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2534) Serinc PF03348.10 EGO22736.1 - 0.0081 14.9 4.5 0.0093 14.7 3.1 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Jiraiya PF15038.1 EGO22736.1 - 0.051 12.9 4.5 0.045 13.1 2.1 1.7 1 1 1 2 2 2 0 Jiraiya Strabismus PF06638.6 EGO22736.1 - 0.2 9.9 4.2 0.24 9.6 2.9 1.1 1 0 0 1 1 1 0 Strabismus protein DUF1129 PF06570.6 EGO22736.1 - 4.4 6.5 6.2 0.87 8.8 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PAP2_C PF14360.1 EGO22736.1 - 5.4 7.3 9.4 0.93 9.8 1.4 2.6 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Wzy_C PF04932.10 EGO22736.1 - 5.9 6.6 7.1 15 5.3 4.9 1.8 1 1 0 1 1 1 0 O-Antigen ligase Mu-like_Com PF10122.4 EGO22738.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com UBX PF00789.15 EGO22739.1 - 2.2e-08 34.0 0.0 5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EGO22739.1 - 2.2e-08 33.4 0.0 4.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain CAF-1_p150 PF11600.3 EGO22739.1 - 0.01 15.2 17.5 0.022 14.1 12.1 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EF-hand_7 PF13499.1 EGO22740.1 - 1.4e-13 50.7 0.0 1.9e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGO22740.1 - 2.1e-12 45.7 0.3 4.3e-05 23.0 0.1 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EGO22740.1 - 5.3e-11 40.9 0.1 0.00034 19.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EGO22740.1 - 6e-07 28.9 0.3 0.00018 21.0 0.0 3.5 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 EGO22740.1 - 1.2e-06 28.3 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EGO22740.1 - 0.0035 16.6 0.2 1.2 8.6 0.0 2.7 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.8 EGO22740.1 - 0.021 14.4 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SapB_1 PF05184.10 EGO22740.1 - 0.16 11.8 0.0 21 5.0 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 WD40 PF00400.27 EGO22742.1 - 0.0058 16.4 0.0 0.27 11.1 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2201_N PF13203.1 EGO22742.1 - 2.7 7.0 7.0 6.5 5.8 4.8 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain YL1_C PF08265.6 EGO22743.1 - 5.4e-14 51.4 0.1 7.7e-14 50.9 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF221 PF02714.10 EGO22744.1 - 6.2e-103 344.0 21.5 1.3e-102 343.0 14.9 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO22744.1 - 6.1e-35 120.0 8.5 6.1e-35 120.0 5.9 2.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGO22744.1 - 9.4e-13 48.5 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EGO22744.1 - 0.0014 18.5 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO22744.1 - 0.04 13.5 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGO22745.1 - 2.3e-11 43.1 13.5 6.8e-07 28.9 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat LysM PF01476.15 EGO22745.1 - 1e-08 34.9 4.5 2.8e-05 23.8 0.1 3.1 3 0 0 3 3 3 2 LysM domain AA_permease PF00324.16 EGO22746.1 - 0.0097 14.2 0.6 0.0098 14.2 0.4 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.14 EGO22747.1 - 2.5e-66 224.1 0.0 3.2e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO22747.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EGO22747.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO22747.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EGO22747.1 - 0.13 12.0 0.0 0.61 9.9 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO22747.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MitMem_reg PF13012.1 EGO22747.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function CMAS PF02353.15 EGO22748.1 - 9.5e-67 224.9 0.0 1.2e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGO22748.1 - 8.5e-12 45.0 0.0 7.7e-11 41.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO22748.1 - 2e-09 37.8 0.0 1.8e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO22748.1 - 7e-06 26.5 0.0 3.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO22748.1 - 7.6e-05 23.0 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGO22748.1 - 7.7e-05 22.0 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EGO22748.1 - 0.00011 22.6 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO22748.1 - 0.00016 21.7 0.0 0.0013 18.6 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO22748.1 - 0.00038 20.0 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO22748.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGO22748.1 - 0.029 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EGO22748.1 - 0.095 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) YIF1 PF03878.10 EGO22749.1 - 3.9e-77 258.6 0.7 4.9e-77 258.3 0.5 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EGO22749.1 - 1.1e-06 28.2 1.6 1.9e-06 27.4 1.1 1.3 1 0 0 1 1 1 1 Yip1 domain V1R PF03402.9 EGO22750.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R p450 PF00067.17 EGO22751.1 - 1.3e-61 208.5 0.0 1.3e-60 205.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Nrap PF03813.9 EGO22752.1 - 1.4e-226 754.4 0.0 1.6e-226 754.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein BESS PF02944.15 EGO22752.1 - 0.16 11.5 0.8 0.47 10.0 0.5 1.9 2 0 0 2 2 2 0 BESS motif UQ_con PF00179.21 EGO22753.1 - 1.3e-39 134.8 0.0 1.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGO22753.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EGO22753.1 - 0.038 13.8 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EGO22753.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF601 PF04642.7 EGO22753.1 - 0.63 9.3 5.5 0.82 8.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Longin PF13774.1 EGO22755.1 - 2.5e-15 55.7 0.0 4.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGO22755.1 - 7.7e-15 54.2 1.0 1.5e-14 53.3 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin NACHT PF05729.7 EGO22759.1 - 2.7e-05 23.8 0.0 6.5e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EGO22759.1 - 0.00043 20.4 0.0 0.056 13.6 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EGO22759.1 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO22759.1 - 0.0046 17.1 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGO22759.1 - 0.0054 15.9 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EGO22759.1 - 0.036 14.8 0.0 0.082 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGO22759.1 - 0.037 12.9 0.4 0.051 12.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO22759.1 - 0.058 12.2 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 EGO22759.1 - 0.089 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 EGO22759.1 - 0.13 11.9 0.1 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.1 EGO22759.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain DnaA_N PF11638.3 EGO22761.1 - 0.064 12.8 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain Ribosomal_L38e PF01781.13 EGO22763.1 - 1.1e-27 95.4 0.9 1.3e-27 95.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Peptidase_M50 PF02163.17 EGO22764.1 - 1.2e-12 47.2 0.0 4.8e-11 41.9 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M50 ParA PF10609.4 EGO22765.1 - 7.3e-30 102.6 0.1 1.2e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGO22765.1 - 1.4e-13 50.7 2.9 1e-12 47.8 2.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGO22765.1 - 3.8e-06 26.9 0.0 1.9e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EGO22765.1 - 0.00073 18.6 0.2 0.0094 15.0 0.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EGO22765.1 - 0.0048 16.0 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EGO22765.1 - 0.0049 16.2 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EGO22765.1 - 0.023 13.9 0.0 0.041 13.0 0.0 1.4 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family An_peroxidase PF03098.10 EGO22766.1 - 4e-34 117.8 0.0 2.6e-12 45.9 0.0 4.1 1 1 3 4 4 4 4 Animal haem peroxidase Methyltransf_26 PF13659.1 EGO22769.1 - 0.16 11.9 0.3 13 5.8 0.1 2.1 1 1 1 2 2 2 0 Methyltransferase domain RabGAP-TBC PF00566.13 EGO22771.1 - 2.3e-27 95.8 0.2 3e-27 95.4 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF953 PF06110.6 EGO22772.1 - 1.3e-18 66.5 0.0 1.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 EGO22772.1 - 0.11 12.5 0.1 0.68 9.9 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin-like FR47 PF08445.5 EGO22773.1 - 5.8e-10 38.7 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EGO22773.1 - 6.6e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO22773.1 - 2.2e-09 37.3 0.0 5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO22773.1 - 4.1e-09 36.5 0.0 7.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO22773.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO22773.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO22773.1 - 0.086 12.7 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy PF03171.15 EGO22774.1 - 2.3e-12 47.0 0.0 6.9e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO22774.1 - 1.5e-11 44.8 0.0 3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ADH_zinc_N PF00107.21 EGO22775.1 - 1.4e-11 44.0 0.3 4.8e-11 42.3 0.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO22775.1 - 3.7e-11 44.0 0.0 9e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO22775.1 - 8.7e-08 31.8 1.9 1e-05 25.2 0.1 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGO22775.1 - 0.0016 18.4 0.6 0.0027 17.7 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGO22775.1 - 0.01 15.6 0.1 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_C PF01262.16 EGO22775.1 - 0.031 13.8 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.8 EGO22775.1 - 0.049 12.8 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EGO22775.1 - 0.057 13.3 1.0 0.098 12.5 0.7 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Homeobox PF00046.24 EGO22776.1 - 0.092 12.3 1.3 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Homeobox domain Pex14_N PF04695.8 EGO22776.1 - 0.23 11.5 2.2 0.26 11.3 1.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2422 PF10337.4 EGO22777.1 - 5.5e-65 219.9 8.5 3.4e-56 190.9 0.1 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EGO22777.1 - 6.3e-54 182.9 0.0 2.6e-53 181.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EGO22777.1 - 3.8e-09 36.5 12.3 3.8e-09 36.5 8.5 3.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like UPF0139 PF03669.8 EGO22777.1 - 0.014 14.9 0.1 0.059 12.8 0.1 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) HIT PF01230.18 EGO22778.1 - 4.9e-22 78.2 0.1 8.2e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO22778.1 - 1.3e-13 51.2 0.0 1.7e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGO22778.1 - 0.00071 19.2 0.2 0.0013 18.4 0.2 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1127 PF06568.6 EGO22778.1 - 0.069 12.5 0.3 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) UPF0016 PF01169.14 EGO22779.1 - 1.2e-45 153.5 19.5 1.7e-23 82.5 4.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.14 EGO22779.1 - 0.0027 17.1 8.5 0.0071 15.8 5.9 1.6 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE TerC PF03741.11 EGO22779.1 - 4 6.8 9.4 1.2 8.5 1.5 2.5 2 2 0 2 2 2 0 Integral membrane protein TerC family CinA PF02464.12 EGO22780.1 - 9e-29 99.9 0.4 1e-28 99.7 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein 2OG-FeII_Oxy PF03171.15 EGO22782.1 - 1.4e-11 44.5 0.0 4.5e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO22782.1 - 8.3e-11 42.4 0.0 1.6e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_M56 PF05569.6 EGO22783.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 2OG-FeII_Oxy PF03171.15 EGO22784.1 - 6.7e-12 45.5 0.0 2.3e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO22784.1 - 6.4e-09 36.3 0.0 1.6e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal NACHT PF05729.7 EGO22786.1 - 1.5e-09 37.7 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGO22786.1 - 1.1e-08 35.2 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO22786.1 - 8e-07 29.2 0.0 1.7e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EGO22786.1 - 0.00039 19.5 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EGO22786.1 - 0.00076 18.6 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 EGO22786.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EGO22786.1 - 0.0029 17.8 0.1 0.011 15.9 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO22786.1 - 0.0034 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGO22786.1 - 0.0048 15.7 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 EGO22786.1 - 0.0085 15.1 0.3 1.1 8.1 0.0 2.1 1 1 1 2 2 2 2 KAP family P-loop domain AAA_19 PF13245.1 EGO22786.1 - 0.021 14.5 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EGO22786.1 - 0.051 13.8 0.1 0.31 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO22786.1 - 0.063 13.1 0.3 0.25 11.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGO22786.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DnaA_N PF11638.3 EGO22786.1 - 0.16 11.5 0.5 0.74 9.4 0.4 2.1 1 1 0 1 1 1 0 DnaA N-terminal domain Ank PF00023.25 EGO22787.1 - 0.0035 17.0 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EGO22787.1 - 0.0084 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO22787.1 - 0.016 15.6 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO22787.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat Semialdhyde_dh PF01118.19 EGO22789.1 - 2.2e-07 31.2 0.1 4.9e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EGO22789.1 - 4e-07 29.5 0.0 5.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGO22789.1 - 3.6e-06 26.6 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO22789.1 - 4.2e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO22789.1 - 0.00022 20.2 0.0 0.0014 17.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein DXP_reductoisom PF02670.11 EGO22789.1 - 0.075 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase LSM PF01423.17 EGO22790.1 - 8.6e-16 57.2 0.2 1e-15 57.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO22790.1 - 3.2e-06 26.9 0.2 4.3e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Ras PF00071.17 EGO22791.1 - 7e-38 129.5 0.0 5.8e-36 123.3 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EGO22791.1 - 3.7e-16 59.7 0.0 6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO22791.1 - 3e-08 33.1 0.0 2.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO22791.1 - 0.00027 20.4 0.0 0.001 18.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO22791.1 - 0.00035 19.8 0.0 0.00067 18.8 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO22791.1 - 0.0025 17.7 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGO22791.1 - 0.0041 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EGO22791.1 - 0.12 11.8 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGO22791.1 - 0.29 10.6 0.6 0.53 9.8 0.2 1.5 2 0 0 2 2 2 0 AAA domain DUF566 PF04484.7 EGO22791.1 - 2.9 7.3 7.5 4.6 6.6 5.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) CorA PF01544.13 EGO22792.1 - 6.5e-10 38.5 9.1 1.6e-09 37.2 6.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EGO22793.1 - 9.8e-06 24.7 10.3 3.5e-05 22.9 7.1 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EGO22794.1 - 4.5e-14 52.1 2.4 7.5e-14 51.4 1.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Arif-1 PF06770.6 EGO22794.1 - 0.12 11.6 1.3 0.26 10.6 0.9 1.4 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) CitMHS PF03600.11 EGO22795.1 - 6.8e-10 38.0 29.1 8e-10 37.8 11.8 2.5 2 1 0 2 2 2 2 Citrate transporter Peptidase_C54 PF03416.14 EGO22797.1 - 9e-85 284.1 0.0 4.1e-84 282.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C54 FAD_binding_4 PF01565.18 EGO22798.1 - 8.7e-15 54.4 0.0 1.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO22798.1 - 2.9e-07 30.3 0.1 8.3e-07 28.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like PS_Dcarbxylase PF02666.10 EGO22799.1 - 1.1e-37 129.3 0.0 1.6e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EGO22799.1 - 8.2e-35 119.4 0.1 1.2e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase AHSA1 PF08327.6 EGO22799.1 - 0.03 14.4 0.0 4.6 7.3 0.0 2.5 1 1 1 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein DUF952 PF06108.7 EGO22800.1 - 2.3e-24 85.0 0.0 2.8e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF605 PF04652.11 EGO22803.1 - 1.1 8.5 26.7 0.13 11.5 15.0 2.0 2 1 0 2 2 2 0 Vta1 like UBN2_3 PF14244.1 EGO22805.1 - 3.2e-06 26.7 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO22805.1 - 9.3e-06 24.9 0.1 1.8e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EGO22805.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type tRNA-synt_1 PF00133.17 EGO22806.1 - 1.1e-210 700.7 0.0 5.5e-210 698.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGO22806.1 - 9.5e-35 119.6 0.2 1.8e-34 118.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGO22806.1 - 1.4e-16 60.1 0.0 6.8e-08 31.5 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGO22806.1 - 1e-11 44.4 0.1 3.4e-08 32.9 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EGO22806.1 - 0.00018 21.5 2.2 0.00064 19.7 1.5 2.0 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 EGO22806.1 - 0.031 13.1 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EGO22806.1 - 0.055 12.5 0.0 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC1 PF03109.11 EGO22807.1 - 3e-30 104.6 0.2 5.7e-30 103.7 0.2 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EGO22807.1 - 0.0045 16.7 0.5 0.069 12.8 0.2 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF21 PF01595.15 EGO22808.1 - 7e-32 110.1 1.4 1.3e-31 109.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGO22808.1 - 0.00051 19.7 3.6 0.77 9.5 0.1 4.0 4 0 0 4 4 4 2 CBS domain Saccharop_dh PF03435.13 EGO22809.1 - 6.4e-74 249.2 0.0 8.6e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 EGO22809.1 - 1.6e-16 60.3 0.0 4.3e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EGO22809.1 - 7.2e-10 38.9 0.0 2.7e-09 37.1 0.0 2.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.15 EGO22809.1 - 0.00062 19.8 0.2 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO22809.1 - 0.17 12.1 0.0 0.49 10.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF4381 PF14316.1 EGO22810.1 - 0.041 13.9 0.2 0.045 13.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Mito_fiss_reg PF05308.6 EGO22813.1 - 0.0056 16.0 2.5 0.013 14.9 1.7 1.6 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF846 PF05832.7 EGO22816.1 - 3.8e-53 179.0 7.1 4.9e-53 178.6 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Ring_hydroxyl_A PF00848.14 EGO22818.1 - 0.066 12.8 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) DASH_Hsk3 PF08227.6 EGO22818.1 - 0.88 9.8 5.4 3.1 8.0 1.2 2.2 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like zf-CCHC_3 PF13917.1 EGO22819.1 - 1.3e-06 28.0 1.4 2.2e-06 27.2 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO22819.1 - 3.8e-05 23.3 5.5 6.3e-05 22.7 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO22819.1 - 0.23 10.9 3.6 0.4 10.1 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EGO22820.1 - 7.3e-08 31.9 4.1 1.2e-07 31.3 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO22820.1 - 0.00067 19.3 3.1 0.00067 19.3 2.2 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-nanos PF05741.8 EGO22820.1 - 0.096 12.6 1.1 0.17 11.8 0.4 1.7 2 0 0 2 2 2 0 Nanos RNA binding domain zf-CCHC_4 PF14392.1 EGO22820.1 - 0.24 11.1 2.5 0.41 10.3 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EGO22824.1 - 8.1e-19 67.5 17.3 1e-13 50.7 8.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4193 PF13834.1 EGO22824.1 - 0.14 12.2 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Sec62 PF03839.11 EGO22824.1 - 0.83 9.0 2.5 1.7 7.9 1.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 p450 PF00067.17 EGO22825.1 - 4.3e-47 160.7 0.0 6.8e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EGO22826.1 - 7.1e-10 39.1 1.8 9.8e-10 38.6 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGO22826.1 - 4.2e-08 33.6 0.7 6.8e-06 26.4 0.1 2.7 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_5 PF12695.2 EGO22826.1 - 0.00025 20.8 0.1 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO22826.1 - 0.04 13.4 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Y_phosphatase3 PF13350.1 EGO22828.1 - 1.1e-31 110.3 0.0 5.9e-24 85.1 0.0 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO22828.1 - 6.5e-11 42.1 0.3 7.6e-10 38.7 0.0 2.9 3 0 0 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO22828.1 - 4.6e-06 26.1 0.0 6.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO22828.1 - 7.1e-05 22.2 0.1 0.00084 18.7 0.0 2.5 1 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGO22828.1 - 0.00013 22.0 2.1 0.00053 20.0 1.4 2.1 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EGO22828.1 - 0.0002 20.9 0.3 0.0015 18.0 0.0 2.3 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EGO22828.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.4 1 1 0 1 1 1 0 Myotubularin-like phosphatase domain Exonuc_VII_L PF02601.10 EGO22828.1 - 0.11 11.7 2.6 0.13 11.4 1.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSP70 PF00012.15 EGO22828.1 - 0.11 10.3 7.1 0.15 9.9 4.9 1.1 1 0 0 1 1 1 0 Hsp70 protein APG6 PF04111.7 EGO22828.1 - 0.31 10.0 20.5 0.5 9.3 14.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tox-ODYAM1 PF15642.1 EGO22828.1 - 0.89 8.1 7.4 1.3 7.6 5.2 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF342 PF03961.8 EGO22828.1 - 5.9 5.1 7.5 7.6 4.8 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lyase_aromatic PF00221.14 EGO22829.1 - 2.1e-145 484.8 4.2 2.8e-145 484.3 2.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase MFS_1 PF07690.11 EGO22830.1 - 1.4e-40 139.1 58.5 1.4e-40 139.1 40.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO22830.1 - 3.9e-13 48.7 13.1 3.9e-13 48.7 9.1 3.3 1 1 1 3 3 3 1 Sugar (and other) transporter AMP-binding PF00501.23 EGO22831.1 - 1.5e-157 524.2 0.0 4.6e-80 269.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGO22831.1 - 1.4e-30 106.1 0.0 2e-19 69.5 0.0 3.0 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EGO22831.1 - 8.9e-16 57.9 0.3 9.1e-07 29.0 0.0 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGO22831.1 - 1.8e-08 35.1 2.9 8.2e-05 23.4 0.1 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGO22831.1 - 0.054 12.0 0.0 3.6 5.9 0.0 2.7 3 0 0 3 3 3 0 GH3 auxin-responsive promoter Y_phosphatase3 PF13350.1 EGO22832.1 - 7.1e-35 120.6 0.0 1.6e-34 119.5 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO22832.1 - 3.6e-11 42.9 0.1 8.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO22832.1 - 3.5e-05 23.2 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO22832.1 - 0.00077 18.8 0.0 0.0018 17.6 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGO22832.1 - 0.0037 16.8 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO22832.1 - 0.035 14.1 0.0 0.082 12.9 0.0 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Asp_protease_2 PF13650.1 EGO22834.1 - 6e-06 26.6 0.0 6.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO22834.1 - 8.8e-06 25.4 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO22834.1 - 0.00064 19.6 0.0 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Amidase02_C PF12123.3 EGO22839.1 - 0.0086 15.6 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Med21 PF11221.3 EGO22841.1 - 0.083 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Ribonucleas_3_2 PF11469.3 EGO22841.1 - 0.12 12.5 0.1 0.3 11.3 0.0 1.7 1 1 1 2 2 2 0 Ribonuclease III Retrotrans_gag PF03732.12 EGO22842.1 - 7.9e-06 25.8 0.8 1.4e-05 25.0 0.4 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein Retrotrans_gag PF03732.12 EGO22843.1 - 2.6e-07 30.6 1.4 4.2e-07 29.9 1.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO22843.1 - 0.0001 22.0 2.2 0.00017 21.3 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO22843.1 - 0.024 14.2 1.0 0.064 12.9 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Colicin PF01024.14 EGO22843.1 - 0.093 12.3 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Colicin pore forming domain Nop14 PF04147.7 EGO22845.1 - 0.0089 14.0 8.6 0.011 13.6 6.0 1.1 1 0 0 1 1 1 1 Nop14-like family DUF572 PF04502.8 EGO22845.1 - 0.011 14.9 10.2 0.017 14.3 7.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cellulase PF00150.13 EGO22846.1 - 2.7e-33 115.3 2.4 5e-33 114.4 1.7 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RNase_PH PF01138.16 EGO22847.1 - 2.9e-20 72.9 0.0 4.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Polysacc_deac_1 PF01522.16 EGO22848.1 - 1.9e-28 98.5 0.0 6.8e-28 96.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Secretin_N_2 PF07655.8 EGO22848.1 - 0.78 10.1 12.8 9.5 6.6 6.7 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain ENTH PF01417.15 EGO22849.1 - 5.1e-52 174.9 0.1 9e-52 174.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain Hydrophobin PF01185.13 EGO22850.1 - 7.7e-16 58.3 5.4 1.2e-15 57.6 3.8 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EGO22851.1 - 1.5e-17 63.8 6.4 1.9e-17 63.4 4.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Peptidase_M24 PF00557.19 EGO22853.1 - 2.5e-58 197.0 0.0 3.3e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGO22853.1 - 2.5e-15 56.0 0.0 4.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain 5_nucleotid_C PF02872.13 EGO22855.1 - 1e-25 90.5 0.0 3.9e-25 88.6 0.0 2.0 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain p450 PF00067.17 EGO22856.1 - 7.8e-59 199.3 0.0 1.2e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynactin PF12455.3 EGO22856.1 - 0.11 11.4 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Dynein associated protein Oxidored_FMN PF00724.15 EGO22859.1 - 1.3e-45 155.9 0.0 1.7e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGO22859.1 - 0.0015 17.3 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) HMGL-like PF00682.14 EGO22859.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 HMGL-like DUF4219 PF13961.1 EGO22861.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 EGO22862.1 - 0.025 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO22862.1 - 0.13 11.9 1.4 1.1 8.9 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO22862.1 - 1.6 8.5 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein Kdo PF06293.9 EGO22863.1 - 1e-09 37.7 0.0 3.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO22863.1 - 1.4e-06 28.1 0.0 0.00013 21.7 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGO22863.1 - 1.3e-05 24.5 0.1 4.2e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain EcKinase PF02958.15 EGO22863.1 - 1.6e-05 24.1 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EGO22863.1 - 0.00011 21.5 0.0 0.016 14.5 0.1 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 EGO22863.1 - 0.006 15.6 0.0 0.016 14.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGO22863.1 - 0.0096 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ion_trans PF00520.26 EGO22864.1 - 1e-103 344.7 96.8 7.4e-34 116.7 11.7 5.2 5 0 0 5 5 5 4 Ion transport protein Sporozoite_P67 PF05642.6 EGO22864.1 - 0.77 7.5 0.0 1.1 7.0 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SEP PF08059.8 EGO22865.1 - 5.2e-24 84.3 0.2 1.8e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EGO22865.1 - 9.1e-15 54.4 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 EGO22865.1 - 0.0085 15.4 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 1 Spt20 family Methyltransf_16 PF10294.4 EGO22866.1 - 2.6e-15 56.3 0.0 4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 EGO22866.1 - 0.013 14.5 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Sugar_tr PF00083.19 EGO22867.1 - 3.2e-122 408.3 28.1 3.7e-122 408.1 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO22867.1 - 4e-19 68.5 50.9 2.2e-13 49.6 13.3 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily PI-PLC-X PF00388.14 EGO22869.1 - 8.1e-37 125.8 0.0 1.3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGO22869.1 - 7.1e-26 90.5 0.0 1.5e-25 89.4 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.12 EGO22869.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PIN_4 PF13638.1 EGO22870.1 - 2.3e-07 30.9 0.0 4.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 PIN domain DUF2347 PF09804.4 EGO22871.1 - 4.4e-48 163.9 0.0 6.3e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EGO22871.1 - 0.00047 18.7 0.0 2.3 6.5 0.1 3.2 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.5 EGO22871.1 - 0.00076 19.1 0.0 0.0021 17.7 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Prefoldin PF02996.12 EGO22872.1 - 1.5e-30 105.2 3.0 1.8e-30 105.0 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGO22872.1 - 4.1e-05 23.2 0.5 7.5e-05 22.4 0.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit COG2 PF06148.6 EGO22872.1 - 0.0021 17.9 1.3 0.38 10.6 0.0 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.15 EGO22872.1 - 0.0029 17.3 5.6 0.051 13.3 0.5 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF4407 PF14362.1 EGO22872.1 - 0.0029 16.6 2.1 0.0034 16.3 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Filament PF00038.16 EGO22872.1 - 0.02 14.3 3.1 0.25 10.7 0.2 2.0 2 0 0 2 2 2 0 Intermediate filament protein Spectrin PF00435.16 EGO22872.1 - 0.021 15.0 0.3 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Spectrin repeat TACC PF05010.9 EGO22872.1 - 0.023 14.4 4.9 0.079 12.7 3.4 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Fib_alpha PF08702.5 EGO22872.1 - 0.031 14.4 7.7 0.23 11.5 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EGO22872.1 - 0.034 14.1 1.9 2.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain XkdW PF09636.5 EGO22872.1 - 0.037 13.8 1.3 0.095 12.5 0.2 1.9 2 0 0 2 2 2 0 XkdW protein CENP-F_leu_zip PF10473.4 EGO22872.1 - 0.073 12.9 3.5 1.2 8.9 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.8 EGO22872.1 - 0.099 12.0 3.7 0.29 10.4 0.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.7 EGO22872.1 - 0.1 12.3 2.1 5.6 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EGO22872.1 - 0.11 11.1 6.1 0.91 8.1 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Barstar PF01337.13 EGO22872.1 - 0.11 12.3 0.1 5 7.0 0.1 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Snapin_Pallidin PF14712.1 EGO22872.1 - 0.14 12.4 4.3 6.5 7.1 0.6 2.3 2 0 0 2 2 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 EGO22872.1 - 0.17 9.6 5.9 0.55 8.0 0.3 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Sec16 PF12932.2 EGO22872.1 - 0.18 11.7 1.6 0.25 11.3 0.3 1.9 2 1 1 3 3 2 0 Vesicle coat trafficking protein Sec16 mid-region BLOC1_2 PF10046.4 EGO22872.1 - 0.19 11.9 3.8 6.8 6.8 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.1 EGO22872.1 - 0.39 10.9 3.4 6.8 6.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Baculo_PEP_C PF04513.7 EGO22872.1 - 0.46 10.2 6.1 4.9 6.9 0.5 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4041 PF13250.1 EGO22872.1 - 0.5 9.9 2.3 4.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Sec2p PF06428.6 EGO22872.1 - 0.58 10.0 4.7 5.5 6.9 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cortex-I_coil PF09304.5 EGO22872.1 - 0.87 9.6 6.7 2.2 8.3 0.5 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil CENP-Q PF13094.1 EGO22872.1 - 0.94 9.4 6.6 0.4 10.6 0.6 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3313 PF11769.3 EGO22872.1 - 1.3 8.3 5.7 0.84 8.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) NPV_P10 PF05531.7 EGO22872.1 - 1.7 8.9 6.2 2.7 8.3 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mnd1 PF03962.10 EGO22872.1 - 2.1 7.9 6.6 12 5.4 4.5 1.9 1 1 0 1 1 1 0 Mnd1 family DUF4200 PF13863.1 EGO22872.1 - 6.2 6.7 10.1 4.2 7.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) F-box-like PF12937.2 EGO22873.1 - 0.0032 17.1 0.2 0.0089 15.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like Pro_isomerase PF00160.16 EGO22874.1 - 9e-48 162.3 0.5 1e-47 162.2 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2572 PF10833.3 EGO22875.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DSPc PF00782.15 EGO22878.1 - 1.9e-07 30.7 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO22878.1 - 3.6e-07 30.3 0.1 7.3e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGO22878.1 - 1.9e-06 28.2 0.5 0.016 15.4 0.1 2.4 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO22878.1 - 0.0016 17.8 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.8 EGO22878.1 - 0.0026 17.5 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase (DUF442) Y_phosphatase2 PF03162.8 EGO22878.1 - 0.0044 16.4 0.0 0.011 15.0 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Dak1 PF02733.12 EGO22879.1 - 6.6e-80 268.1 4.3 6.3e-59 199.1 0.0 2.1 1 1 0 2 2 2 2 Dak1 domain Dak2 PF02734.12 EGO22879.1 - 2.7e-35 121.5 0.8 5.9e-35 120.4 0.6 1.6 1 1 0 1 1 1 1 DAK2 domain DUF1926 PF09095.6 EGO22881.1 - 0.076 12.2 0.0 0.1 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1926) Glyco_hydro_16 PF00722.16 EGO22882.1 - 6.4e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Aldo_ket_red PF00248.16 EGO22883.1 - 1.2e-43 148.9 0.0 1.4e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IPT PF01745.11 EGO22883.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Aldo_ket_red PF00248.16 EGO22884.1 - 1.6e-45 155.1 0.0 2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IPT PF01745.11 EGO22884.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Aldo_ket_red PF00248.16 EGO22885.1 - 9.5e-51 172.2 0.0 1.2e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.16 EGO22886.1 - 4.3e-07 29.4 0.1 8.5e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 EGO22887.1 - 1.3e-07 31.0 0.0 2.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Dynamin_M PF01031.15 EGO22889.1 - 3.6e-29 101.4 0.0 2.6e-15 55.9 0.0 2.6 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 EGO22889.1 - 8.7e-16 58.1 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGO22889.1 - 6.8e-10 38.7 0.3 6.8e-10 38.7 0.2 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain EF-hand_9 PF14658.1 EGO22889.1 - 0.0071 16.2 0.0 0.69 9.8 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain CybS PF05328.7 EGO22890.1 - 1.2e-44 151.1 0.1 1.4e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 CybS LamB_YcsF PF03746.11 EGO22892.1 - 3.2e-71 239.2 0.0 3.7e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF4267 PF14087.1 EGO22894.1 - 1.1e-30 105.4 1.1 1.3e-30 105.2 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.1 EGO22894.1 - 0.13 11.7 1.1 0.18 11.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) UPF0197 PF05251.7 EGO22894.1 - 0.54 10.6 2.5 2.5 8.4 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0197) AHS2 PF02626.10 EGO22895.1 - 2.1e-73 246.9 0.0 3e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EGO22895.1 - 1.1e-56 191.4 0.0 2e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 EGO22895.1 - 5.8e-36 123.8 0.0 1.2e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 EGO22895.1 - 2.7e-32 111.1 0.0 9.3e-32 109.4 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGO22895.1 - 9.2e-29 99.5 0.0 1.9e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EGO22895.1 - 1.3e-11 44.6 0.0 3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO22895.1 - 3.1e-09 36.5 0.0 5.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGO22895.1 - 4.6e-09 35.4 0.0 6.5e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EGO22895.1 - 0.00026 20.5 0.7 0.00086 18.8 0.5 1.9 1 1 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.6 EGO22895.1 - 0.052 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGO22895.1 - 0.098 12.3 0.4 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like F-box-like PF12937.2 EGO22896.1 - 0.00039 20.0 0.0 0.00089 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGO22896.1 - 0.056 13.0 0.4 1.6 8.4 0.2 2.9 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO22896.1 - 0.088 12.5 0.6 0.49 10.1 0.3 2.4 3 0 0 3 3 3 0 Leucine rich repeat PS_Dcarbxylase PF02666.10 EGO22898.1 - 3.1e-39 134.3 0.0 4.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EGO22898.1 - 9.6e-39 132.2 0.2 1.3e-38 131.7 0.1 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.1 EGO22898.1 - 0.017 14.8 0.0 0.078 12.7 0.0 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 EGO22898.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 Biotin_lipoyl PF00364.17 EGO22898.1 - 0.13 11.9 0.3 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme F-box-like PF12937.2 EGO22901.1 - 9e-05 22.1 0.0 9e-05 22.1 0.0 3.7 4 1 1 5 5 5 1 F-box-like LRR_4 PF12799.2 EGO22901.1 - 0.00035 20.1 4.6 0.046 13.3 0.5 4.2 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGO22901.1 - 0.017 15.1 2.2 6.8 7.0 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 EGO22901.1 - 0.099 12.4 8.1 4.4 7.1 0.2 4.4 3 2 1 4 4 4 0 Leucine rich repeat Ubiq_cyt_C_chap PF03981.7 EGO22902.1 - 2.1e-07 30.8 0.1 2.2e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Cpn60_TCP1 PF00118.19 EGO22907.1 - 1.8e-117 392.9 4.8 2.1e-117 392.7 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family polyprenyl_synt PF00348.12 EGO22908.1 - 5.9e-71 238.3 0.0 8.4e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Corona_RPol_N PF06478.8 EGO22908.1 - 0.044 12.4 0.3 0.15 10.6 0.1 1.8 1 1 0 2 2 2 0 Coronavirus RPol N-terminus DUF2433 PF10360.4 EGO22908.1 - 0.061 13.6 0.3 2 8.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2433) MMR_HSR1 PF01926.18 EGO22910.1 - 5.5e-10 39.2 0.0 9.6e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO22910.1 - 7.5e-05 23.0 0.3 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EGO22910.1 - 0.00016 20.8 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 EGO22910.1 - 0.00028 20.3 0.0 0.0006 19.2 0.0 1.4 1 1 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.13 EGO22910.1 - 0.0004 19.9 0.1 0.0011 18.5 0.1 1.8 1 1 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 EGO22910.1 - 0.00096 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGO22910.1 - 0.0018 18.1 0.4 0.0044 16.8 0.3 1.7 1 1 0 1 1 1 1 Dynamin family DUF258 PF03193.11 EGO22910.1 - 0.0035 16.5 0.0 0.0068 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO22910.1 - 0.0044 17.0 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EGO22910.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO22910.1 - 0.038 14.7 0.0 0.18 12.6 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGO22910.1 - 0.039 13.4 0.2 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 EGO22910.1 - 0.041 13.1 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.21 EGO22910.1 - 0.044 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EGO22910.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EGO22910.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGO22910.1 - 0.056 13.7 0.7 0.11 12.8 0.5 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EGO22910.1 - 0.061 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_15 PF13175.1 EGO22910.1 - 0.15 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EGO22910.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Acyl-CoA_dh_M PF02770.14 EGO22911.1 - 8.8e-06 25.1 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain gag-asp_proteas PF13975.1 EGO22912.1 - 3.3e-08 33.2 0.0 5.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO22912.1 - 9.4e-05 22.8 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO22912.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Chromo PF00385.19 EGO22914.1 - 3.6e-10 39.3 0.2 4.1e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGO22914.1 - 0.00044 19.8 0.1 0.00057 19.5 0.1 1.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain YicC_N PF03755.8 EGO22914.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region Chromo_shadow PF01393.14 EGO22914.1 - 0.023 14.5 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Chromo shadow domain Mtf2_C PF14061.1 EGO22914.1 - 0.08 12.8 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 CusF_Ec PF11604.3 EGO22915.1 - 0.014 15.2 2.9 32 4.4 0.0 4.2 3 2 2 5 5 5 0 Copper binding periplasmic protein CusF zf-CCHC PF00098.18 EGO22916.1 - 4.6e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO22916.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO22916.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle FAM220 PF15487.1 EGO22917.1 - 5.5 6.2 6.3 7.2 5.8 4.3 1.3 1 0 0 1 1 1 0 FAM220 family DUF2668 PF10873.3 EGO22918.1 - 0.0015 18.6 1.1 0.002 18.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) DUF1708 PF08101.6 EGO22919.1 - 1.2e-13 50.6 0.0 3.6e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EGO22919.1 - 0.0091 15.6 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Fascin PF06268.8 EGO22920.1 - 3.4e-19 68.9 0.1 5.9e-05 23.1 0.0 4.9 3 2 2 5 5 5 4 Fascin domain FRG1 PF06229.7 EGO22920.1 - 2e-06 27.3 0.7 0.39 10.1 0.0 4.3 4 1 0 4 4 4 3 FRG1-like family DUF3430 PF11912.3 EGO22920.1 - 0.00027 20.8 7.4 0.074 12.8 0.3 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3430) DUF4098 PF13345.1 EGO22920.1 - 2.3 8.2 14.1 8.1 6.4 0.2 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4098) SKG6 PF08693.5 EGO22922.1 - 0.054 12.8 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2867 PF11066.3 EGO22922.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) Rifin_STEVOR PF02009.11 EGO22922.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2613 PF11021.3 EGO22922.1 - 0.72 9.6 6.4 0.12 12.1 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Hydantoinase_A PF01968.13 EGO22924.1 - 1.2e-88 296.9 0.0 1.8e-88 296.3 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGO22924.1 - 6.2e-48 162.6 0.1 8e-45 152.4 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Acyl-CoA_dh_M PF02770.14 EGO22925.1 - 4.1e-06 26.2 0.0 7.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1 PF01926.18 EGO22926.1 - 5.5e-10 39.2 0.0 9.6e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO22926.1 - 7.5e-05 23.0 0.3 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EGO22926.1 - 0.00016 20.8 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 EGO22926.1 - 0.00028 20.3 0.0 0.0006 19.2 0.0 1.4 1 1 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.13 EGO22926.1 - 0.0004 19.9 0.1 0.0011 18.5 0.1 1.8 1 1 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 EGO22926.1 - 0.00096 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGO22926.1 - 0.0018 18.1 0.4 0.0044 16.8 0.3 1.7 1 1 0 1 1 1 1 Dynamin family DUF258 PF03193.11 EGO22926.1 - 0.0035 16.5 0.0 0.0068 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO22926.1 - 0.0044 17.0 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EGO22926.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO22926.1 - 0.038 14.7 0.0 0.18 12.6 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGO22926.1 - 0.039 13.4 0.2 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 EGO22926.1 - 0.041 13.1 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.21 EGO22926.1 - 0.044 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EGO22926.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EGO22926.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGO22926.1 - 0.056 13.7 0.7 0.11 12.8 0.5 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EGO22926.1 - 0.061 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_15 PF13175.1 EGO22926.1 - 0.15 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EGO22926.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO22928.1 - 1.8e-08 34.3 0.0 5e-08 32.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO22928.1 - 4.3e-06 25.9 0.0 6.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EGO22928.1 - 0.00055 19.7 0.4 0.0045 16.8 0.2 2.2 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.22 EGO22928.1 - 0.0011 19.3 2.3 0.0033 17.7 1.6 2.2 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EGO22928.1 - 0.0016 17.6 0.0 0.0044 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGO22928.1 - 0.0017 18.8 0.0 0.0038 17.7 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 EGO22928.1 - 0.013 15.8 0.8 0.029 14.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGO22928.1 - 0.017 14.5 0.3 0.027 13.9 0.2 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EGO22928.1 - 0.021 14.3 0.4 0.088 12.3 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGO22928.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ras PF00071.17 EGO22928.1 - 0.059 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.13 EGO22928.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF815 PF05673.8 EGO22928.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGO22928.1 - 0.15 12.0 0.1 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Chromo PF00385.19 EGO22929.1 - 1.4e-09 37.4 0.1 1.5e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGO22929.1 - 0.00053 19.6 0.1 0.00068 19.2 0.1 1.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain YicC_N PF03755.8 EGO22929.1 - 0.023 14.6 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region Chromo_shadow PF01393.14 EGO22929.1 - 0.027 14.2 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Chromo shadow domain Mtf2_C PF14061.1 EGO22929.1 - 0.08 12.8 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 gag-asp_proteas PF13975.1 EGO22930.1 - 2.6e-07 30.3 0.0 4.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EGO22930.1 - 3.2e-06 27.1 0.9 3.2e-06 27.1 0.6 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EGO22930.1 - 0.00036 20.9 0.1 0.002 18.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 EGO22930.1 - 0.097 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease NOA36 PF06524.7 EGO22931.1 - 1.4 8.1 5.1 2 7.5 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EGO22931.1 - 2.6 8.3 11.2 4.4 7.6 7.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EGO22931.1 - 9.2 4.8 10.0 13 4.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2456 PF10445.4 EGO22932.1 - 0.016 15.0 2.6 0.28 11.1 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF1649 PF07855.7 EGO22932.1 - 0.051 13.2 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1649) Orthopox_F8 PF05886.6 EGO22933.1 - 0.02 14.6 4.9 0.54 10.1 0.3 2.9 3 0 0 3 3 3 0 Orthopoxvirus F8 protein DUF1604 PF07713.8 EGO22933.1 - 0.16 11.7 0.5 0.3 10.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Trm112p PF03966.11 EGO22934.1 - 1.1e-20 73.7 0.1 1.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-NADH-PPase PF09297.6 EGO22934.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain AurF PF11583.3 EGO22934.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF RNase_PH PF01138.16 EGO22935.1 - 1.3e-18 67.5 0.0 1.9e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGO22935.1 - 6.5e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF605 PF04652.11 EGO22936.1 - 4.2 6.6 10.4 4.3 6.6 7.2 1.1 1 0 0 1 1 1 0 Vta1 like HNH PF01844.18 EGO22939.1 - 0.0012 18.7 2.1 0.0027 17.5 1.4 1.7 1 1 0 1 1 1 1 HNH endonuclease C1_1 PF00130.17 EGO22939.1 - 0.034 13.8 1.2 0.088 12.5 0.8 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1033 PF06279.6 EGO22939.1 - 0.11 12.2 0.0 4.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) DUF3337 PF11816.3 EGO22940.1 - 8.6e-49 166.7 0.0 4.4e-48 164.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EGO22940.1 - 9.8e-26 88.6 22.4 1.6e-07 30.8 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Peptidase_M48 PF01435.13 EGO22941.1 - 1.2e-27 96.9 0.0 1.9e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF3533 PF12051.3 EGO22942.1 - 2e-76 257.2 13.3 2.3e-76 257.0 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 EGO22942.1 - 3.2e-12 46.1 12.2 4.2e-12 45.7 8.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein CBM_20 PF00686.14 EGO22943.1 - 1.4e-28 98.3 1.3 2.9e-28 97.3 0.3 2.0 2 0 0 2 2 2 1 Starch binding domain Alpha-amylase PF00128.19 EGO22943.1 - 6.5e-16 58.6 0.0 1.2e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EGO22943.1 - 2.7e-09 37.0 0.0 7.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pex14_N PF04695.8 EGO22944.1 - 0.11 12.5 0.5 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nicastrin PF05450.10 EGO22944.1 - 0.12 11.5 0.2 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Nicastrin DUF308 PF03729.8 EGO22944.1 - 0.19 11.7 1.1 0.39 10.7 0.8 1.5 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) adh_short_C2 PF13561.1 EGO22945.1 - 1.7e-27 96.7 0.3 2.3e-27 96.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO22945.1 - 3e-26 92.3 3.1 3.9e-26 91.9 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO22945.1 - 3.5e-10 39.8 1.2 5.4e-10 39.2 0.8 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO22945.1 - 0.0022 17.4 0.0 0.048 13.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO22945.1 - 0.0024 16.6 0.3 0.0033 16.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO22945.1 - 0.015 15.3 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding Wax2_C PF12076.3 EGO22945.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain adh_short PF00106.20 EGO22946.1 - 3.5e-31 108.3 7.0 5.4e-31 107.7 4.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO22946.1 - 1.4e-26 93.7 1.4 1.7e-26 93.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO22946.1 - 1.1e-12 48.0 4.6 1.8e-12 47.2 3.2 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGO22946.1 - 0.0002 20.1 0.5 0.0003 19.5 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO22946.1 - 0.0052 16.2 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family IlvN PF07991.7 EGO22946.1 - 0.071 12.4 0.5 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 EGO22946.1 - 0.27 11.2 3.9 0.52 10.2 2.7 1.7 1 1 0 1 1 1 0 NADH(P)-binding zf-GRF PF06839.7 EGO22948.1 - 0.69 9.8 6.1 0.47 10.4 0.6 2.2 1 1 1 2 2 2 0 GRF zinc finger Polysacc_deac_1 PF01522.16 EGO22950.1 - 2e-15 56.4 0.0 5.1e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase Aldedh PF00171.17 EGO22953.1 - 2.8e-181 602.9 0.0 3.1e-181 602.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1242 PF06842.7 EGO22954.1 - 1.4e-18 66.0 1.8 1.9e-18 65.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) 7TM-7TMR_HD PF07698.6 EGO22954.1 - 0.037 13.4 3.0 0.042 13.2 2.1 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF805 PF05656.9 EGO22954.1 - 0.11 12.2 0.7 0.12 12.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) SMC_N PF02463.14 EGO22955.1 - 2.6e-18 66.0 0.0 2.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO22955.1 - 0.046 13.6 0.1 0.071 13.0 0.0 1.3 2 0 0 2 2 2 0 AAA domain Topo_Zn_Ribbon PF08272.6 EGO22955.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF2481 PF10654.4 EGO22956.1 - 0.14 11.8 3.0 0.19 11.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) SMC_N PF02463.14 EGO22957.1 - 8.8e-37 126.4 0.2 1.1e-36 126.0 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO22957.1 - 4.8e-15 56.4 0.3 5.2e-15 56.3 0.2 1.0 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EGO22957.1 - 1.4e-07 31.8 0.3 1.5e-07 31.7 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO22957.1 - 3.7e-06 26.3 0.0 7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EGO22957.1 - 1.4e-05 24.3 0.3 1.5e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF2813 PF11398.3 EGO22957.1 - 0.0085 15.2 0.0 0.0097 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) ABC_tran PF00005.22 EGO22957.1 - 0.037 14.3 2.7 0.092 13.0 1.9 1.8 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EGO22957.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Glyco_hydro_88 PF07470.8 EGO22958.1 - 4.9e-18 65.2 0.1 6.9e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MAD PF05557.8 EGO22960.1 - 8e-30 103.5 3.4 1.6e-29 102.5 2.3 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein Vps35 PF03635.12 EGO22960.1 - 0.063 11.4 0.1 0.081 11.0 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 APG6 PF04111.7 EGO22960.1 - 0.082 11.9 14.2 0.033 13.2 2.2 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 MdoG PF04349.7 EGO22960.1 - 0.13 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG AATF-Che1 PF13339.1 EGO22960.1 - 0.86 9.7 11.2 20 5.3 7.8 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Med30 PF11315.3 EGO22960.1 - 1 9.4 12.1 0.11 12.6 3.3 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 CCDC-167 PF15188.1 EGO22960.1 - 1.1 9.2 14.3 0.073 13.0 3.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FlgN PF05130.7 EGO22960.1 - 5.3 7.2 10.3 2 8.6 2.8 2.2 1 1 1 2 2 2 0 FlgN protein IncA PF04156.9 EGO22960.1 - 8.4 5.9 20.4 10 5.6 7.1 2.4 2 1 0 2 2 2 0 IncA protein DUF262 PF03235.9 EGO22961.1 - 1.3e-18 67.7 1.0 2.6e-18 66.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 OPT PF03169.10 EGO22965.1 - 8e-199 662.0 68.1 9.1e-199 661.9 47.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NIF PF03031.13 EGO22966.1 - 6.7e-10 38.8 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L17 PF01196.14 EGO22969.1 - 9.3e-34 115.8 0.1 2.1e-33 114.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 WD40 PF00400.27 EGO22970.1 - 1.7e-48 160.7 19.5 3.9e-11 42.3 0.0 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGO22970.1 - 0.0004 20.1 12.3 1.1 8.8 0.0 4.4 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term GTP_EFTU PF00009.22 EGO22971.1 - 8.6e-58 194.8 0.0 1.7e-57 193.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGO22971.1 - 4.5e-34 116.5 0.0 3.9e-33 113.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 EGO22971.1 - 5.3e-29 99.8 0.0 1e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGO22971.1 - 1.2e-22 79.5 0.1 2.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO22971.1 - 2.1e-11 43.7 0.0 5.4e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Sec34 PF04136.10 EGO22973.1 - 1.8e-32 112.1 0.6 5.3e-32 110.7 0.3 1.9 1 1 0 1 1 1 1 Sec34-like family DinB_2 PF12867.2 EGO22973.1 - 0.0019 18.5 1.2 0.15 12.4 0.3 2.7 2 0 0 2 2 2 1 DinB superfamily Vps5 PF09325.5 EGO22973.1 - 0.023 13.9 0.8 0.046 12.9 0.6 1.4 1 0 0 1 1 1 0 Vps5 C terminal like KIP1 PF07765.7 EGO22973.1 - 0.038 13.8 0.7 0.15 11.8 0.3 2.2 1 1 0 1 1 1 0 KIP1-like protein GCN5L1 PF06320.8 EGO22973.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) BLOC1_2 PF10046.4 EGO22973.1 - 0.13 12.4 1.3 1.2 9.3 0.3 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.7 EGO22973.1 - 1.2 7.4 3.4 0.8 8.0 0.0 2.2 3 0 0 3 3 3 0 Fusaric acid resistance protein family MMR_HSR1 PF01926.18 EGO22974.1 - 1.6e-19 70.0 0.4 8.8e-15 54.6 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO22974.1 - 8.7e-07 28.3 1.2 8.3e-06 25.1 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGO22974.1 - 0.00089 18.4 0.1 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGO22974.1 - 0.0017 17.8 0.0 0.19 11.1 0.0 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO22974.1 - 0.0018 18.1 1.7 0.32 10.8 0.1 3.1 2 1 1 3 3 3 1 Dynamin family ArgK PF03308.11 EGO22974.1 - 0.0024 16.7 0.0 0.0056 15.4 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EGO22974.1 - 0.02 14.8 1.3 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.11 EGO22974.1 - 0.022 13.8 1.4 0.24 10.5 0.1 2.2 2 0 0 2 2 2 0 AIG1 family cobW PF02492.14 EGO22974.1 - 0.024 14.0 0.1 0.94 8.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 2-Hacid_dh_C PF02826.14 EGO22974.1 - 0.038 13.1 0.2 0.9 8.6 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Miro PF08477.8 EGO22974.1 - 0.065 13.7 0.4 0.85 10.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EGO22974.1 - 0.087 12.5 0.1 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3377 PF11857.3 EGO22975.1 - 1.5 8.4 3.9 12 5.6 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Glyco_trans_2_3 PF13632.1 EGO22976.1 - 3.5e-05 23.5 1.6 3.6e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DGOK PF05035.7 EGO22976.1 - 0.065 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase DUF3471 PF11954.3 EGO22976.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Glyco_hydro_16 PF00722.16 EGO22978.1 - 1.9e-13 50.1 1.1 9.2e-13 47.8 0.4 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EGO22979.1 - 3.1e-50 170.5 0.3 3.1e-50 170.5 0.2 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO22979.1 - 1.2e-09 38.3 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO22979.1 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGO22979.1 - 0.096 11.9 0.1 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 LRR_8 PF13855.1 EGO22983.1 - 0.17 11.6 0.8 0.72 9.6 0.5 1.9 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EGO22983.1 - 2.2 7.9 4.5 17 5.1 1.0 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Cauli_VI PF01693.11 EGO22986.1 - 0.00014 21.8 0.1 0.0002 21.2 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin PepSY_TM_1 PF13172.1 EGO22988.1 - 5.6 6.8 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix NUDIX_2 PF13869.1 EGO22992.1 - 6.2e-85 283.2 0.0 7e-85 283.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ras PF00071.17 EGO22993.1 - 2.4e-54 183.1 0.0 2.9e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO22993.1 - 1.5e-17 64.1 0.0 2.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO22993.1 - 3.6e-14 52.3 0.0 4.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO22993.1 - 9.2e-08 31.4 0.0 1.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO22993.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO22993.1 - 0.0015 18.0 0.0 0.0035 16.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 EGO22993.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin SerH PF06873.6 EGO22995.1 - 0.0036 15.9 1.8 0.004 15.8 1.3 1.2 1 0 0 1 1 1 1 Cell surface immobilisation antigen SerH CFC PF09443.5 EGO22995.1 - 5.3 6.7 8.6 12 5.6 5.7 1.8 1 1 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Peptidase_M36 PF02128.10 EGO22996.1 - 1.9e-130 435.1 9.0 9.3e-130 432.8 6.2 2.2 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGO22996.1 - 3.6e-06 26.3 1.8 3.6e-06 26.3 1.3 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EGO22996.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_23 PF13489.1 EGO22997.1 - 2.7e-14 53.2 0.0 3.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO22997.1 - 1.9e-08 34.6 0.0 2.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO22997.1 - 7.5e-07 28.8 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO22997.1 - 2e-06 28.3 0.0 3.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO22997.1 - 2.9e-06 27.6 0.0 5.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGO22997.1 - 0.051 13.2 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EGO22997.1 - 0.057 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 EGO22997.1 - 0.095 13.0 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGO22997.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PAP2 PF01569.16 EGO22998.1 - 6.8e-12 45.1 9.5 6.8e-12 45.1 6.6 2.6 1 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EGO22998.1 - 4.3e-10 39.4 11.8 4.3e-10 39.4 8.2 1.8 2 1 0 2 2 2 1 PAP2 superfamily HSP70 PF00012.15 EGO23002.1 - 0.11 10.3 0.0 15 3.3 0.0 2.9 3 0 0 3 3 3 0 Hsp70 protein GTP_cyclohydroI PF01227.17 EGO23003.1 - 0.025 13.8 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase I Strumpellin PF10266.4 EGO23004.1 - 0.0059 14.0 1.4 0.0077 13.7 1.0 1.1 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DUF342 PF03961.8 EGO23004.1 - 0.044 12.2 4.6 0.066 11.6 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 EGO23004.1 - 0.059 13.6 5.6 0.31 11.3 4.0 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DUF2968 PF11180.3 EGO23004.1 - 0.12 11.7 7.1 0.31 10.3 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IncA PF04156.9 EGO23004.1 - 0.19 11.3 10.3 0.38 10.3 7.1 1.4 1 0 0 1 1 1 0 IncA protein DUF16 PF01519.11 EGO23004.1 - 0.2 11.8 4.7 0.37 11.0 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 APG6 PF04111.7 EGO23004.1 - 0.23 10.4 11.7 0.45 9.5 8.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 EGO23004.1 - 0.27 9.6 3.2 0.45 8.8 2.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4164 PF13747.1 EGO23004.1 - 0.33 11.1 9.4 4.7 7.4 5.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 EGO23004.1 - 0.42 10.9 9.4 2 8.8 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EGO23004.1 - 0.72 9.8 10.3 1.7 8.6 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF607 PF04678.8 EGO23004.1 - 2 8.2 5.9 7.3 6.4 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DivIC PF04977.10 EGO23004.1 - 6.2 6.3 9.0 13 5.3 2.7 2.5 1 1 1 2 2 2 0 Septum formation initiator PhyH PF05721.8 EGO23007.1 - 3.3e-10 40.3 0.0 5.7e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) dsrm PF00035.20 EGO23008.1 - 0.38 11.3 0.1 0.38 11.3 0.0 2.9 3 0 0 3 3 3 0 Double-stranded RNA binding motif SNARE_assoc PF09335.6 EGO23009.1 - 2.7e-13 50.1 10.1 2.7e-13 50.1 7.0 2.2 2 1 1 3 3 3 1 SNARE associated Golgi protein Pkinase PF00069.20 EGO23010.1 - 6.3e-44 150.0 0.0 9.6e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23010.1 - 3.3e-38 131.2 0.0 4.5e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4238 PF14022.1 EGO23010.1 - 1.3e-05 24.5 0.0 2.8e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.18 EGO23010.1 - 2.4e-05 24.1 0.1 7.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGO23010.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase RIO1 PF01163.17 EGO23010.1 - 0.16 11.2 0.3 1 8.6 0.0 2.4 3 0 0 3 3 3 0 RIO1 family DUF4243 PF14027.1 EGO23011.1 - 8.4e-93 311.3 0.3 1e-92 311.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4243 PF14027.1 EGO23012.1 - 9.1e-92 307.9 0.5 1.1e-91 307.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Peptidase_S9 PF00326.16 EGO23013.1 - 1.8e-37 128.6 0.0 3e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO23013.1 - 1.9e-12 47.1 0.1 3.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EGO23013.1 - 2.7e-08 33.3 0.3 7.5e-08 31.9 0.2 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EGO23013.1 - 1.9e-07 31.2 0.3 2.8e-06 27.3 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EGO23013.1 - 5e-05 22.6 0.4 0.0056 15.9 0.0 2.3 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.8 EGO23013.1 - 6.6e-05 22.5 0.1 0.0004 20.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EGO23013.1 - 8.6e-05 22.3 0.1 0.0014 18.4 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.7 EGO23013.1 - 0.00012 21.5 0.1 0.02 14.5 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.15 EGO23013.1 - 0.0012 18.4 0.1 0.014 14.9 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 EGO23013.1 - 0.003 17.0 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EGO23013.1 - 0.004 16.6 0.0 0.32 10.4 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EGO23013.1 - 0.035 12.6 0.0 0.061 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EGO23014.1 - 3.7e-37 127.6 0.2 7.8e-37 126.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO23014.1 - 3.6e-10 39.7 0.0 7.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO23014.1 - 8.7e-06 25.7 0.0 5.4e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGO23014.1 - 2.7e-05 23.9 0.1 0.00012 21.8 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.7 EGO23014.1 - 6.1e-05 22.5 3.4 0.06 13.0 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.8 EGO23014.1 - 0.00023 20.7 0.1 0.0007 19.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EGO23014.1 - 0.00075 18.0 0.4 0.0072 14.8 0.3 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) LIP PF03583.9 EGO23014.1 - 0.00077 18.7 0.1 0.0044 16.2 0.0 2.0 1 1 1 2 2 2 1 Secretory lipase DLH PF01738.13 EGO23014.1 - 0.0013 18.0 0.1 0.0039 16.4 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EGO23014.1 - 0.0041 16.7 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EGO23014.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 EGO23014.1 - 0.017 14.5 0.3 3.1 7.1 0.0 2.3 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PhoPQ_related PF10142.4 EGO23014.1 - 0.022 13.2 0.0 0.051 12.0 0.0 1.6 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.16 EGO23015.1 - 4.5e-36 124.0 0.1 9e-36 123.0 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO23015.1 - 1.6e-09 37.6 0.0 4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO23015.1 - 9.4e-08 32.2 0.0 4.2e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO23015.1 - 9.3e-06 25.3 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 EGO23015.1 - 5.9e-05 22.3 0.0 0.0034 16.6 0.0 2.2 1 1 1 2 2 2 1 Secretory lipase BAAT_C PF08840.6 EGO23015.1 - 8.3e-05 22.3 0.2 0.00051 19.8 0.2 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EGO23015.1 - 0.00028 20.4 0.1 0.053 12.9 0.2 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.7 EGO23015.1 - 0.0003 20.3 4.7 0.091 12.4 0.1 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 EGO23015.1 - 0.0012 17.3 0.1 0.005 15.3 0.1 1.9 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 EGO23015.1 - 0.0023 17.2 0.0 0.0062 15.8 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGO23015.1 - 0.013 14.9 0.0 0.14 11.5 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 EGO23015.1 - 0.022 13.2 0.0 0.038 12.4 0.0 1.4 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DPPIV_N PF00930.16 EGO23015.1 - 0.049 12.1 0.2 4.8 5.6 0.0 2.9 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cys_Met_Meta_PP PF01053.15 EGO23016.1 - 1.3e-143 477.9 0.0 1.5e-143 477.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO23016.1 - 1.6e-13 50.4 0.5 1e-12 47.7 0.2 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGO23016.1 - 2.3e-12 46.5 0.0 3.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGO23016.1 - 1.2e-08 34.0 0.3 2.8e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGO23016.1 - 2.2e-05 23.7 0.0 5.2e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EGO23016.1 - 9.8e-05 20.8 0.0 0.00013 20.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EGO23016.1 - 0.007 15.0 0.0 0.0097 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein DUF4361 PF14274.1 EGO23016.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) DUF4243 PF14027.1 EGO23017.1 - 2.8e-83 280.0 0.8 3.4e-83 279.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) F-box-like PF12937.2 EGO23018.1 - 0.00071 19.2 0.4 0.0017 18.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like FA_hydroxylase PF04116.8 EGO23019.1 - 9.7e-13 48.5 21.6 9.7e-13 48.5 14.9 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Xan_ur_permease PF00860.15 EGO23020.1 - 1.2e-29 102.9 26.1 1.5e-28 99.4 18.1 2.1 1 1 0 1 1 1 1 Permease family DUF2650 PF10853.3 EGO23022.1 - 0.74 9.3 3.1 9.8 5.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) EPL1 PF10513.4 EGO23025.1 - 1.7e-18 67.3 0.7 1.4e-17 64.4 0.0 2.6 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-H2C2_2 PF13465.1 EGO23027.1 - 9.2e-08 32.0 8.6 1.3e-07 31.5 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGO23027.1 - 1.2e-05 25.3 0.7 1.2e-05 25.3 0.5 4.6 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGO23027.1 - 0.00026 20.7 4.9 0.42 10.5 0.1 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EGO23027.1 - 0.0056 16.9 0.4 0.0056 16.9 0.3 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 EGO23027.1 - 0.027 14.6 0.3 4.2 7.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IL12p40_C PF10420.4 EGO23027.1 - 0.063 13.3 1.4 0.36 10.9 0.6 2.0 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus TAFII28 PF04719.9 EGO23028.1 - 8.2e-29 99.2 0.0 9.8e-29 98.9 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 EGO23028.1 - 0.00029 20.8 0.0 0.00042 20.3 0.0 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EamA PF00892.15 EGO23033.1 - 1.2e-23 83.4 29.2 1.4e-14 54.1 5.5 2.8 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGO23033.1 - 1.2e-06 28.7 33.1 9.3e-06 25.8 4.7 3.5 2 2 1 3 3 3 2 Multidrug resistance efflux transporter DUF914 PF06027.7 EGO23033.1 - 0.00018 20.4 1.7 0.00038 19.3 1.2 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Trp_oprn_chp PF09534.5 EGO23033.1 - 0.3 10.6 3.8 0.11 12.0 0.2 2.1 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TPT PF03151.11 EGO23033.1 - 0.84 9.2 26.7 0.99 9.0 7.8 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF3433 PF11915.3 EGO23035.1 - 6e-13 48.7 0.7 3.3e-12 46.3 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Dehydratase_hem PF13816.1 EGO23036.1 - 0.054 12.5 0.1 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Haem-containing dehydratase Hydrophobin PF01185.13 EGO23037.1 - 8.7e-11 42.1 1.1 1e-10 41.8 0.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4381 PF14316.1 EGO23038.1 - 0.051 13.6 0.2 0.057 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SKG6 PF08693.5 EGO23039.1 - 0.00045 19.4 1.3 0.001 18.3 0.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EGO23039.1 - 0.0012 17.2 0.0 0.0017 16.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.8 EGO23039.1 - 0.004 17.4 1.1 0.004 17.4 0.7 2.7 3 0 0 3 3 3 1 Alphavirus glycoprotein J DUF4328 PF14219.1 EGO23039.1 - 0.021 14.0 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF3188 PF11384.3 EGO23039.1 - 0.021 14.3 2.4 0.043 13.4 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Beta-APP PF03494.8 EGO23039.1 - 0.13 11.7 4.1 0.24 10.9 2.8 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Tubulin PF00091.20 EGO23040.1 - 1.8e-69 233.8 0.0 3.5e-69 232.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO23040.1 - 6e-49 165.2 0.1 9.5e-49 164.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGO23040.1 - 2.1e-06 27.7 0.0 6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGO23040.1 - 0.039 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain CPSase_L_D2 PF02786.12 EGO23041.1 - 8.2e-112 371.5 0.2 1.4e-79 266.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EGO23041.1 - 8.3e-46 155.8 0.0 6e-45 153.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EGO23041.1 - 1.2e-45 154.2 0.0 2.8e-45 153.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EGO23041.1 - 5e-44 149.3 0.0 1.1e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EGO23041.1 - 1.2e-42 144.5 0.1 3e-42 143.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGO23041.1 - 3.8e-41 139.6 0.0 1.7e-19 69.9 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EGO23041.1 - 2.3e-37 128.3 0.0 5e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EGO23041.1 - 1.2e-36 126.2 0.1 7.6e-23 81.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGO23041.1 - 1.6e-20 73.1 0.3 2.5e-08 33.0 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EGO23041.1 - 1.4e-19 69.7 0.0 8.2e-19 67.3 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EGO23041.1 - 1.3e-17 63.8 0.0 6.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGO23041.1 - 2.1e-14 53.2 0.0 2.5e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EGO23041.1 - 4.9e-06 26.1 0.0 0.00026 20.4 0.0 2.9 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EGO23041.1 - 1.2e-05 25.2 0.1 0.058 13.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EGO23041.1 - 0.00011 21.7 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Sld5 PF05916.6 EGO23044.1 - 3.8e-06 27.1 0.8 1.2e-05 25.5 0.5 1.9 1 1 0 1 1 1 1 GINS complex protein Thioesterase PF00975.15 EGO23044.1 - 0.086 13.0 0.4 0.29 11.3 0.1 1.7 1 1 1 2 2 2 0 Thioesterase domain Cyt-b5 PF00173.23 EGO23045.1 - 2e-09 37.1 0.0 2.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 EGO23049.1 - 1.7e-41 142.1 61.9 9e-41 139.7 41.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO23049.1 - 3.9e-05 22.4 33.8 0.00026 19.7 2.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter WBP-1 PF11669.3 EGO23049.1 - 0.1 12.6 0.4 0.68 10.0 0.1 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 tRNA-synt_1b PF00579.20 EGO23050.1 - 7.3e-59 199.2 0.0 1.6e-58 198.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DnaJ PF00226.26 EGO23051.1 - 2.5e-27 94.3 1.1 2.5e-27 94.3 0.8 1.7 2 0 0 2 2 2 1 DnaJ domain MFS_1 PF07690.11 EGO23052.1 - 4e-39 134.3 64.5 4e-39 134.3 44.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Histone PF00125.19 EGO23053.1 - 1e-13 51.1 0.1 1.7e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO23053.1 - 2.4e-05 24.4 0.1 4.4e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGO23053.1 - 9.3e-05 22.3 0.5 0.00019 21.3 0.1 1.8 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGO23053.1 - 0.0008 19.4 0.4 0.0023 17.9 0.0 1.9 1 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGO23053.1 - 0.07 12.3 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGO23053.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FtsJ PF01728.14 EGO23054.1 - 5.4e-44 150.3 0.0 6.9e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase TFIIIC_sub6 PF10419.4 EGO23055.1 - 7.1e-08 31.7 0.1 1e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 TFIIIC subunit Tox-REase-7 PF15649.1 EGO23055.1 - 0.54 10.4 3.4 4.2 7.5 0.2 2.3 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 7 Filament PF00038.16 EGO23057.1 - 0.057 12.8 20.9 0.31 10.4 14.4 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF3299 PF11736.3 EGO23057.1 - 0.091 12.6 2.2 0.14 12.0 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) DUF745 PF05335.8 EGO23057.1 - 0.28 10.6 21.7 0.39 10.1 14.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Alg14 PF08660.6 EGO23057.1 - 0.57 10.1 3.5 0.42 10.5 0.6 1.8 1 1 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Toxin-deaminase PF14424.1 EGO23057.1 - 1.1 9.2 6.5 0.68 9.9 2.5 1.8 1 1 1 2 2 2 0 The BURPS668_1122 family of deaminases DUF1675 PF07897.6 EGO23057.1 - 1.7 8.4 9.3 1.8 8.3 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) zf-CpG_bind_C PF12269.3 EGO23057.1 - 3.8 6.9 13.3 0.75 9.2 5.7 1.9 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain COG2 PF06148.6 EGO23057.1 - 5.7 6.8 15.1 1.7 8.5 4.0 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DDHD PF02862.12 EGO23057.1 - 6.9 6.3 7.6 8.8 6.0 5.3 1.2 1 0 0 1 1 1 0 DDHD domain HSP70 PF00012.15 EGO23059.1 - 0.064 11.1 0.0 0.065 11.1 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein CCDC92 PF14916.1 EGO23060.1 - 0.00012 21.5 3.4 0.00027 20.4 2.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Septin PF00735.13 EGO23062.1 - 1.5e-114 381.8 0.3 2.1e-114 381.2 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGO23062.1 - 1.7e-07 31.2 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO23062.1 - 6.3e-07 28.7 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGO23062.1 - 1.5e-05 24.5 0.5 0.00017 21.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGO23062.1 - 0.00078 19.9 0.1 0.0024 18.3 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGO23062.1 - 0.00086 18.8 1.2 0.075 12.5 0.0 2.9 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EGO23062.1 - 0.00086 18.8 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EGO23062.1 - 0.0021 18.1 2.2 0.018 15.2 0.1 2.8 2 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EGO23062.1 - 0.0031 17.8 0.2 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 EGO23062.1 - 0.005 16.4 0.0 0.0099 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EGO23062.1 - 0.005 15.9 0.1 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Bac_DnaA PF00308.13 EGO23062.1 - 0.0058 16.3 1.4 0.23 11.0 0.1 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_16 PF13191.1 EGO23062.1 - 0.0062 16.5 0.4 0.045 13.7 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Ras PF00071.17 EGO23062.1 - 0.0065 15.8 0.2 0.024 14.0 0.2 2.0 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 EGO23062.1 - 0.012 15.4 6.4 0.74 9.6 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Pox_A32 PF04665.7 EGO23062.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Arch_ATPase PF01637.13 EGO23062.1 - 0.02 14.6 0.1 0.02 14.6 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EGO23062.1 - 0.032 13.0 0.5 0.066 12.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 EGO23062.1 - 0.036 13.7 0.1 0.099 12.3 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGO23062.1 - 0.037 13.5 2.2 0.09 12.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EGO23062.1 - 0.038 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO23062.1 - 0.042 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EGO23062.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EGO23062.1 - 0.14 11.3 0.5 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Myc-LZ PF02344.10 EGO23062.1 - 0.31 10.6 4.4 5.7 6.6 0.1 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA PF00004.24 EGO23062.1 - 0.36 11.0 2.1 0.91 9.7 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cep57_CLD_2 PF14197.1 EGO23062.1 - 5.8 6.9 10.0 0.37 10.7 2.4 2.4 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 zf-CCHH PF10283.4 EGO23064.1 - 0.72 9.7 3.7 2.1 8.2 2.6 1.8 1 1 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif Pkinase PF00069.20 EGO23065.1 - 2.9e-06 26.6 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO23065.1 - 0.00025 20.8 0.1 0.00052 19.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO23065.1 - 0.00032 19.8 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EGO23065.1 - 0.0066 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO23065.1 - 0.0084 15.4 0.1 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family ubiquitin PF00240.18 EGO23066.1 - 0.037 13.4 0.1 0.064 12.6 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF863 PF05904.6 EGO23066.1 - 0.046 12.0 0.2 0.066 11.4 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) BMFP PF04380.8 EGO23067.1 - 0.052 13.6 0.2 1.4 9.1 0.6 2.2 2 0 0 2 2 2 0 Membrane fusogenic activity NYD-SP28_assoc PF14775.1 EGO23067.1 - 0.066 12.9 0.3 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain Retrotrans_gag PF03732.12 EGO23067.1 - 0.27 11.3 3.3 1.5 8.9 2.3 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein HA2 PF04408.18 EGO23069.1 - 7.8e-28 96.4 0.1 1.6e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO23069.1 - 4.4e-24 84.4 0.0 1.3e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO23069.1 - 6.6e-11 41.9 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO23069.1 - 9.3e-07 28.4 0.2 2e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO23069.1 - 9.6e-06 25.7 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EGO23069.1 - 0.00011 21.6 0.1 0.00025 20.5 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EGO23069.1 - 0.023 14.5 0.1 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EGO23069.1 - 0.029 14.6 0.3 0.081 13.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGO23069.1 - 0.036 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EGO23069.1 - 0.036 12.9 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EGO23069.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EGO23069.1 - 0.082 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 EGO23069.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EGO23069.1 - 0.12 11.4 0.1 0.42 9.6 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin Myosin_head PF00063.16 EGO23069.1 - 0.14 10.2 0.0 0.19 9.6 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Arch_ATPase PF01637.13 EGO23069.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Redoxin PF08534.5 EGO23070.1 - 9.9e-29 99.7 0.0 1.2e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGO23070.1 - 2e-12 46.8 0.0 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGO23070.1 - 0.0074 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Proteasome PF00227.21 EGO23072.1 - 1e-29 103.2 0.1 1.2e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 EGO23072.1 - 0.034 13.7 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain MRG PF05712.8 EGO23073.1 - 2.9e-50 169.9 0.1 4.4e-50 169.3 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EGO23073.1 - 1.3e-09 37.6 0.3 2.2e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EGO23073.1 - 0.083 12.5 0.4 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 EGO23074.1 - 6.1e-28 97.6 0.0 7.5e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23074.1 - 4.3e-09 35.8 0.0 4.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO23074.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mago_nashi PF02792.9 EGO23077.1 - 5e-76 253.2 0.3 5.9e-76 253.0 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Ribosomal_S10 PF00338.17 EGO23078.1 - 5.5e-22 77.4 0.0 8.5e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e EnY2 PF10163.4 EGO23079.1 - 1.4e-19 69.8 0.1 1.6e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 OAR PF03826.12 EGO23079.1 - 0.13 11.7 1.5 0.23 11.0 1.0 1.4 1 0 0 1 1 1 0 OAR domain DUF4451 PF14616.1 EGO23080.1 - 1.2e-19 70.3 0.7 1.4e-19 70.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.19 EGO23081.1 - 1.9e-44 151.5 0.1 2.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Toprim PF01751.17 EGO23081.1 - 0.068 13.1 0.0 7.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Toprim domain Herpes_UL49_5 PF05702.6 EGO23081.1 - 0.3 10.9 2.5 1 9.2 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein Pkinase PF00069.20 EGO23082.1 - 3.3e-06 26.4 0.0 5.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO23082.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO23082.1 - 0.00047 19.2 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO23082.1 - 0.018 14.3 0.0 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.12 EGO23082.1 - 0.031 13.3 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SAM_decarbox PF01536.11 EGO23082.1 - 0.04 12.5 0.1 0.062 11.9 0.1 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Aldedh PF00171.17 EGO23085.1 - 8.7e-126 419.9 0.0 1e-125 419.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO23085.1 - 1.6e-08 33.7 0.0 2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) BAR_2 PF10455.4 EGO23086.1 - 4.4e-50 170.2 0.6 1.8e-49 168.2 0.4 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EGO23086.1 - 7e-13 48.6 1.2 4.6e-12 45.9 0.8 1.9 1 1 0 1 1 1 1 BAR domain Uds1 PF15456.1 EGO23086.1 - 0.039 13.9 3.7 0.9 9.5 0.0 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Fez1 PF06818.10 EGO23086.1 - 0.19 11.7 5.3 0.42 10.6 3.7 1.6 1 0 0 1 1 1 0 Fez1 Proteasome PF00227.21 EGO23087.1 - 1.2e-47 161.6 0.1 1.4e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGO23087.1 - 1.6e-13 49.6 1.5 3.6e-13 48.5 1.0 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal SpoIIE PF07228.7 EGO23088.1 - 8.5e-06 25.6 0.0 2.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EGO23088.1 - 3.6e-05 23.2 0.0 0.049 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGO23088.1 - 0.00068 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Glycogen_syn PF05693.8 EGO23090.1 - 0 1078.7 0.0 0 1078.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 EGO23090.1 - 6.7e-08 32.3 0.3 1.5e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EGO23090.1 - 1.3e-07 31.1 0.0 0.00019 20.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGO23090.1 - 2.3e-05 24.6 5.4 3.5e-05 24.0 3.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF92 PF01940.11 EGO23091.1 - 5e-56 189.3 7.4 6.3e-55 185.7 5.1 1.9 1 1 0 1 1 1 1 Integral membrane protein DUF92 OTCace_N PF02729.16 EGO23092.1 - 6.1e-46 155.6 0.0 8.4e-46 155.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EGO23092.1 - 9.2e-41 139.3 0.0 1.4e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain JmjN PF02375.12 EGO23093.1 - 3.1e-14 52.1 0.1 4.8e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 jmjN domain FHA PF00498.21 EGO23096.1 - 0.00039 20.4 0.1 0.00086 19.3 0.1 1.6 1 1 0 1 1 1 1 FHA domain TrkA_C PF02080.16 EGO23096.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-C domain CAP59_mtransfer PF11735.3 EGO23098.1 - 4.4e-47 160.3 0.0 7.7e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SLS PF14611.1 EGO23099.1 - 5.7e-09 35.7 0.3 1.6e-08 34.2 0.2 1.7 1 1 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Retrotrans_gag PF03732.12 EGO23100.1 - 7.3e-05 22.7 0.5 7.3e-05 22.7 0.3 2.3 3 1 1 4 4 4 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO23100.1 - 0.031 14.2 0.7 0.052 13.4 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Chon_Sulph_att PF06566.6 EGO23101.1 - 0.74 9.4 6.7 0.77 9.3 4.6 1.0 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain DEC-1_N PF04625.8 EGO23101.1 - 6.2 5.3 9.1 6.4 5.3 6.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SNAPc19 PF15497.1 EGO23102.1 - 0.1 12.7 0.7 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 FTCD PF02971.9 EGO23105.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Formiminotransferase domain OPT PF03169.10 EGO23107.1 - 1.5e-195 651.2 67.3 1.7e-195 651.0 46.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_C12 PF01088.16 EGO23108.1 - 0.087 11.9 1.6 0.095 11.8 1.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 FXR1P_C PF12235.3 EGO23110.1 - 0.041 13.9 0.2 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Thymosin PF01290.15 EGO23110.1 - 0.92 9.1 5.4 0.2 11.2 1.1 1.8 2 0 0 2 2 2 0 Thymosin beta-4 family ATP_bind_1 PF03029.12 EGO23111.1 - 6.9e-78 261.4 0.0 9.5e-78 261.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EGO23111.1 - 3.5e-05 23.3 0.1 0.00054 19.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGO23111.1 - 0.00061 18.6 0.0 0.19 10.4 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 EGO23111.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO23111.1 - 0.0023 18.7 0.2 0.02 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EGO23111.1 - 0.0029 17.0 0.5 0.017 14.5 0.4 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 EGO23111.1 - 0.0035 17.2 0.0 0.01 15.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EGO23111.1 - 0.012 15.0 0.7 0.056 12.8 0.5 1.9 1 1 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 EGO23111.1 - 0.017 14.3 0.0 0.077 12.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 EGO23111.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO23111.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EGO23111.1 - 0.035 13.5 0.1 5.1 6.4 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EGO23111.1 - 0.057 12.0 0.0 0.093 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein SRP54 PF00448.17 EGO23111.1 - 0.087 12.2 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.15 EGO23111.1 - 0.09 11.4 1.0 12 4.4 0.1 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_30 PF13604.1 EGO23111.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGO23111.1 - 0.15 10.8 0.1 0.55 9.0 0.0 1.9 3 0 0 3 3 3 0 NB-ARC domain DUF258 PF03193.11 EGO23111.1 - 0.16 11.1 0.1 0.58 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 EGO23112.1 - 4e-78 262.1 0.0 4.6e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23112.1 - 1.8e-35 122.2 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO23112.1 - 0.0019 17.9 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO23112.1 - 0.0027 16.7 0.0 0.11 11.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EGO23112.1 - 0.041 12.7 0.1 0.099 11.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 adh_short PF00106.20 EGO23115.1 - 1.7e-32 112.6 5.8 2.3e-32 112.2 4.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23115.1 - 2.7e-30 105.9 4.3 3.2e-30 105.6 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO23115.1 - 1.9e-13 50.4 3.6 3e-13 49.8 2.5 1.2 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 EGO23115.1 - 0.0024 17.9 0.4 0.44 10.7 0.3 2.5 1 1 0 1 1 1 1 Helix-hairpin-helix domain Epimerase PF01370.16 EGO23115.1 - 0.13 11.7 1.1 0.29 10.5 0.7 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO23115.1 - 0.13 12.2 4.9 0.76 9.7 3.3 2.2 1 1 0 1 1 1 0 NADH(P)-binding RVP_2 PF08284.6 EGO23117.1 - 8.1e-06 25.8 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO23117.1 - 7.6e-05 23.1 0.0 9.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO23117.1 - 0.0049 16.6 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Siva PF05458.7 EGO23117.1 - 0.054 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) adh_short PF00106.20 EGO23118.1 - 1.5e-29 103.0 5.6 2.1e-29 102.5 3.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23118.1 - 1.9e-29 103.1 2.7 2.5e-29 102.7 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO23118.1 - 2.1e-12 47.0 3.7 3.5e-12 46.3 2.6 1.3 1 0 0 1 1 1 1 KR domain HAD PF12710.2 EGO23118.1 - 0.025 14.7 0.1 0.056 13.6 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HHH_5 PF14520.1 EGO23118.1 - 0.05 13.7 0.2 1.1 9.4 0.1 2.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain Pro_CA PF00484.14 EGO23119.1 - 4.7e-21 75.3 0.0 5.5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 EGO23120.1 - 3.4e-25 88.8 0.0 4.2e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Glucosaminidase PF01832.15 EGO23120.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase p450 PF00067.17 EGO23121.1 - 7.5e-69 232.4 0.0 8.7e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVP_2 PF08284.6 EGO23122.1 - 3.8e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO23122.1 - 0.031 14.7 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease YmzC PF14157.1 EGO23122.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 YmzC-like protein Ank_2 PF12796.2 EGO23124.1 - 5e-15 55.6 1.5 1.1e-12 48.1 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO23124.1 - 1.9e-08 34.6 0.4 4.7e-06 26.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO23124.1 - 2e-08 33.6 0.2 0.0035 17.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EGO23124.1 - 2e-08 33.6 0.9 7.3e-05 22.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGO23124.1 - 6e-08 32.6 1.6 2.4e-06 27.5 0.2 3.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Sec7_N PF12783.2 EGO23125.1 - 1.1e-31 109.5 1.6 1.1e-29 103.0 0.2 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGO23125.1 - 2.3e-05 23.8 0.0 0.00018 20.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) zf-CCHC PF00098.18 EGO23127.1 - 1.5e-07 31.0 3.5 2.9e-07 30.0 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle FAM180 PF15173.1 EGO23127.1 - 0.049 13.4 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 FAM180 family zf-CCHC_4 PF14392.1 EGO23127.1 - 0.17 11.5 1.0 0.38 10.4 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle PAT1 PF09770.4 EGO23127.1 - 2.3 6.3 14.8 3.6 5.7 10.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4452 PF14618.1 EGO23128.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) zf-C3HC4_2 PF13923.1 EGO23132.1 - 4.4e-09 36.2 10.7 6.6e-09 35.6 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO23132.1 - 1e-08 34.8 10.9 1.6e-08 34.2 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO23132.1 - 2.3e-08 33.5 10.0 3.5e-08 32.9 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO23132.1 - 2.9e-07 30.0 6.4 4.1e-07 29.5 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO23132.1 - 6e-06 26.2 9.1 2e-05 24.6 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO23132.1 - 1.1e-05 25.0 9.5 1.6e-05 24.5 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO23132.1 - 0.00077 19.2 9.9 0.0013 18.5 6.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2602 PF10782.4 EGO23132.1 - 0.0069 16.1 0.4 0.012 15.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2602) zf-RING_UBOX PF13445.1 EGO23132.1 - 0.043 13.5 6.0 0.081 12.6 4.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGO23132.1 - 0.098 12.5 5.1 0.39 10.5 3.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EGO23132.1 - 0.13 12.0 4.1 0.24 11.2 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EGO23132.1 - 0.13 11.8 6.6 0.26 10.9 4.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EGO23132.1 - 0.22 11.0 6.9 0.64 9.5 4.8 1.7 1 1 0 1 1 1 0 P-11 zinc finger Homeobox PF00046.24 EGO23134.1 - 1.2e-14 53.6 1.6 2.2e-14 52.8 1.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGO23134.1 - 0.021 14.4 2.0 0.092 12.4 0.1 2.5 2 0 0 2 2 2 0 Homeobox KN domain Bromodomain PF00439.20 EGO23136.1 - 1.8e-11 43.7 0.0 2.3e-09 37.0 0.0 2.6 1 1 0 1 1 1 1 Bromodomain MutL_C PF08676.6 EGO23137.1 - 3e-26 91.7 0.2 5.7e-26 90.8 0.1 1.4 1 1 0 1 1 1 1 MutL C terminal dimerisation domain G-alpha PF00503.15 EGO23138.1 - 3.7e-107 358.3 0.0 7.7e-102 340.8 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EGO23138.1 - 4.5e-14 52.0 0.1 3.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EGO23138.1 - 9.8e-05 21.8 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EGO23138.1 - 0.0011 18.2 0.0 0.38 9.8 0.0 2.6 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EGO23138.1 - 0.062 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EGO23138.1 - 0.13 11.6 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NEMO PF11577.3 EGO23138.1 - 0.48 10.2 4.2 1.1 9.0 2.9 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Pyr_redox PF00070.22 EGO23139.1 - 2.8e-12 46.8 0.8 6.2e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO23139.1 - 1.5e-11 44.5 0.6 0.0006 19.7 0.1 4.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO23139.1 - 5.8e-05 22.1 0.6 0.41 9.4 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO23139.1 - 0.0034 17.4 0.2 4.2 7.3 0.0 3.4 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO23139.1 - 0.0057 15.6 0.0 0.014 14.3 0.0 1.5 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EGO23139.1 - 0.068 11.7 0.6 0.68 8.4 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EGO23139.1 - 0.089 12.5 0.8 0.48 10.1 0.0 2.2 1 1 1 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EGO23139.1 - 0.17 11.5 0.4 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EGO23139.1 - 0.17 10.2 0.4 0.73 8.2 0.0 2.0 2 1 1 3 3 3 0 HI0933-like protein Glyco_hydro_28 PF00295.12 EGO23140.1 - 2.6e-52 177.8 16.2 3.3e-52 177.4 11.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EGO23140.1 - 4.6e-06 26.4 21.7 4.6e-06 26.4 15.1 1.9 1 1 0 1 1 1 1 Right handed beta helix region DUF1565 PF07602.6 EGO23140.1 - 5.9e-05 22.3 7.0 8.2e-05 21.8 3.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) AMP-binding PF00501.23 EGO23141.1 - 1.3e-61 208.2 0.0 1.8e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EGO23141.1 - 6.2e-32 111.6 0.0 1.9e-31 110.0 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EGO23141.1 - 1e-09 38.5 0.0 2.5e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGO23141.1 - 6.1e-08 32.8 0.1 2.3e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO23141.1 - 0.011 15.5 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO23141.1 - 0.089 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_N PF08240.7 EGO23142.1 - 7e-11 41.8 0.0 1.1e-08 34.7 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO23142.1 - 5.2e-08 32.5 0.1 3.3e-07 29.9 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO23142.1 - 0.14 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 EGO23142.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aminotran_1_2 PF00155.16 EGO23143.1 - 8e-22 77.6 0.0 1.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGO23143.1 - 0.00024 19.8 0.0 0.00033 19.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.16 EGO23144.1 - 1.3e-21 76.9 0.0 1.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGO23144.1 - 0.00026 19.6 0.0 0.00036 19.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase TFIIB PF00382.14 EGO23148.1 - 4.5e-38 128.8 0.9 3.4e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGO23148.1 - 3.8e-17 62.2 14.8 5.2e-15 55.4 3.0 3.5 2 1 0 2 2 2 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EGO23148.1 - 9.7e-08 31.2 4.8 4.2e-07 29.1 3.2 2.2 1 1 1 2 2 2 2 TFIIB zinc-binding Cyclin_N PF00134.18 EGO23148.1 - 1.4e-06 27.9 0.5 0.031 13.8 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain A2L_zn_ribbon PF08792.5 EGO23148.1 - 0.011 15.1 1.8 0.021 14.3 1.2 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain RRN7 PF11781.3 EGO23148.1 - 0.027 13.9 1.9 0.053 13.0 1.3 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EGO23148.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Myf5 PF12232.3 EGO23149.1 - 0.31 11.6 2.9 0.38 11.3 2.0 1.1 1 0 0 1 1 1 0 Myogenic determination factor 5 WTF PF03303.8 EGO23153.1 - 0.12 11.8 0.7 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 WTF protein DUF4448 PF14610.1 EGO23153.1 - 0.15 11.5 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) OpgC_C PF10129.4 EGO23153.1 - 0.18 10.4 4.8 1.6 7.2 0.9 2.1 2 0 0 2 2 2 0 OpgC protein Aldo_ket_red PF00248.16 EGO23154.1 - 1.3e-51 175.0 0.0 1.7e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAMP PF00672.20 EGO23156.1 - 2.8e-46 155.5 24.6 1.6e-08 34.6 0.1 8.1 7 1 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 EGO23156.1 - 5.6e-28 96.8 0.1 2.1e-27 95.0 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO23156.1 - 1e-22 80.2 0.2 4e-22 78.3 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGO23156.1 - 1.6e-17 63.2 2.3 5.5e-17 61.5 0.7 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Syntaxin PF00804.20 EGO23156.1 - 0.11 12.6 3.7 13 5.9 0.1 4.5 3 1 0 3 3 3 0 Syntaxin DUF2365 PF10157.4 EGO23156.1 - 0.38 10.6 15.2 23 4.8 0.0 7.1 5 3 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) AcylCoA_dehyd_C PF12186.3 EGO23156.1 - 2.6 7.9 14.0 25 4.7 0.0 6.6 7 1 1 8 8 8 0 Acyl-CoA dehydrogenase C terminal Fungal_trans PF04082.13 EGO23157.1 - 4.3e-19 68.4 0.8 7.5e-19 67.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nup84_Nup100 PF04121.8 EGO23158.1 - 1.9e-84 283.6 0.0 3.8e-84 282.7 0.0 1.5 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.9 EGO23158.1 - 0.0013 17.0 0.1 0.0041 15.3 0.0 1.7 2 0 0 2 2 2 1 Nup93/Nic96 PPR_1 PF12854.2 EGO23158.1 - 0.19 11.2 0.2 0.84 9.1 0.1 2.1 2 0 0 2 2 2 0 PPR repeat PLDc PF00614.17 EGO23159.1 - 5.7e-18 64.0 2.0 1.1e-09 37.7 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGO23159.1 - 5.4e-15 55.2 0.0 5.8e-07 29.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain Pro_isomerase PF00160.16 EGO23160.1 - 1e-48 165.4 0.2 1.1e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMC_oxred_N PF00732.14 EGO23161.1 - 3.7e-65 220.0 0.0 5.3e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO23161.1 - 8e-35 120.2 0.0 2.1e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EGO23161.1 - 3.2e-05 23.0 0.1 4.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGO23161.1 - 0.0012 17.7 1.3 0.82 8.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EGO23161.1 - 0.016 14.2 0.1 0.046 12.8 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EGO23161.1 - 0.026 14.3 0.1 0.063 13.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO23161.1 - 0.046 12.6 1.6 0.84 8.4 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO23161.1 - 0.13 10.8 0.2 0.23 10.0 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EGO23161.1 - 0.18 10.2 0.6 0.31 9.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein PIP5K PF01504.13 EGO23162.1 - 6.6e-54 182.6 0.0 1.3e-53 181.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase adh_short PF00106.20 EGO23163.1 - 4.3e-11 42.9 0.2 7.3e-11 42.2 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23163.1 - 1.5e-06 28.2 0.2 2.2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 EGO23163.1 - 0.0093 15.5 0.1 0.036 13.6 0.0 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.13 EGO23163.1 - 0.051 13.2 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EGO23163.1 - 0.12 12.4 0.2 0.28 11.2 0.0 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1598 PF07643.6 EGO23163.1 - 0.15 12.0 0.0 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) Glyco_hydro_28 PF00295.12 EGO23165.1 - 7.6e-56 189.4 12.5 1e-55 188.9 8.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 EGO23166.1 - 7e-49 166.5 10.1 1.1e-48 165.8 7.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Aa_trans PF01490.13 EGO23167.1 - 8.3e-28 96.9 33.9 1.4e-27 96.2 23.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.20 EGO23169.1 - 3.8e-05 22.9 0.0 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF1899 PF08953.6 EGO23171.1 - 0.072 12.7 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Septin PF00735.13 EGO23173.1 - 0.057 12.4 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Septin DUF4349 PF14257.1 EGO23174.1 - 0.0021 17.3 0.9 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4349) CCDC155 PF14662.1 EGO23174.1 - 0.48 9.9 10.4 0.031 13.8 2.7 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Ribosomal_S4Pg PF11993.3 EGO23174.1 - 0.65 9.7 7.2 0.38 10.5 0.7 2.2 2 0 0 2 2 2 0 Ribosomal S4P (gammaproteobacterial) Bap31 PF05529.7 EGO23174.1 - 1.5 8.2 7.2 0.12 11.8 1.5 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DDE_1 PF03184.14 EGO23175.1 - 1.1e-22 80.3 0.0 1.4e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO23175.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SPC12 PF06645.8 EGO23176.1 - 4.5e-23 80.8 0.3 5.1e-23 80.6 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Pkinase PF00069.20 EGO23177.1 - 2.4e-72 243.2 0.0 6e-72 241.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23177.1 - 2.5e-36 125.0 0.0 2.3e-35 121.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGO23177.1 - 5.2e-14 51.4 0.0 8.8e-14 50.6 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EGO23177.1 - 1.8e-06 27.2 0.1 3e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO23177.1 - 5.7e-05 22.9 0.9 0.001 18.8 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO23177.1 - 0.00039 19.4 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 EGO23177.1 - 0.0059 15.8 0.6 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EGO23177.1 - 0.05 12.9 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Aa_trans PF01490.13 EGO23179.1 - 4.7e-35 120.8 37.4 5.5e-35 120.6 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TauD PF02668.11 EGO23181.1 - 8.9e-47 159.9 0.1 1.2e-46 159.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1469 PF07332.6 EGO23183.1 - 3.7 7.3 8.8 14 5.4 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF455 PF04305.9 EGO23184.1 - 1.9e-89 299.3 0.0 2.2e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) DUF1435 PF07256.7 EGO23185.1 - 0.2 11.6 2.0 13 5.8 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1435) WD40 PF00400.27 EGO23186.1 - 2.4e-52 173.0 27.8 1.1e-13 50.5 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat NACHT PF05729.7 EGO23186.1 - 1.1e-11 44.6 0.0 2.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Nucleoporin_N PF08801.6 EGO23186.1 - 6.3e-07 28.4 1.1 0.0076 15.0 0.0 3.3 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EGO23186.1 - 1.3e-06 26.8 2.7 0.0082 14.3 0.0 3.7 1 1 3 4 4 4 2 Nucleoporin Nup120/160 AAA_16 PF13191.1 EGO23186.1 - 4.1e-06 26.9 0.5 1.6e-05 24.9 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.1 EGO23186.1 - 0.00028 20.4 1.6 0.019 14.4 0.2 2.8 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 EGO23186.1 - 0.00048 18.5 0.7 0.081 11.2 0.1 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 EGO23186.1 - 0.0066 15.6 0.4 1.9 7.6 0.0 3.4 2 1 2 4 4 4 1 TUP1-like enhancer of split APS_kinase PF01583.15 EGO23186.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 EGO23186.1 - 0.021 13.8 0.1 0.041 12.8 0.1 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EGO23186.1 - 0.048 13.4 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EGO23186.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.12 EGO23188.1 - 2.7e-06 27.3 0.3 6.9e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein p450 PF00067.17 EGO23189.1 - 1.1e-66 225.3 0.0 1.6e-64 218.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Cecropin PF00272.14 EGO23189.1 - 0.17 11.4 0.5 5.4 6.6 0.2 2.4 2 0 0 2 2 2 0 Cecropin family p450 PF00067.17 EGO23190.1 - 1.1e-69 235.1 0.0 1.2e-50 172.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 F-box-like PF12937.2 EGO23191.1 - 3e-08 33.2 1.8 6e-08 32.2 0.3 2.2 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 EGO23192.1 - 2.4e-10 39.9 1.2 0.022 14.4 0.0 5.3 4 1 0 4 4 4 4 TPR repeat TPR_14 PF13428.1 EGO23192.1 - 8.2e-08 32.2 10.7 0.021 15.4 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO23192.1 - 5.9e-07 29.1 1.4 17 5.8 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO23192.1 - 1.6e-05 25.1 1.7 1.2 9.4 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO23192.1 - 2.7e-05 23.7 15.2 0.27 11.2 0.0 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO23192.1 - 2.8e-05 24.6 10.8 0.38 11.5 0.0 5.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGO23192.1 - 0.0088 16.3 4.5 2.3 8.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 EGO23192.1 - 0.021 14.6 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.23 EGO23192.1 - 0.057 13.0 8.6 8.3 6.2 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO23194.1 - 4.4e-54 180.0 10.8 6.9e-16 57.6 0.1 7.0 4 3 3 8 8 8 7 TPR repeat TPR_1 PF00515.23 EGO23194.1 - 3.8e-38 127.5 7.3 0.00027 20.4 0.0 11.1 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGO23194.1 - 3.6e-36 120.1 13.5 2.9e-05 23.6 0.0 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGO23194.1 - 9.1e-25 86.7 12.8 3.3e-07 30.7 0.0 7.4 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGO23194.1 - 8.1e-23 80.1 15.6 4.2e-05 23.4 0.0 7.4 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGO23194.1 - 1.3e-16 59.0 10.5 0.00075 19.1 0.0 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGO23194.1 - 1.6e-16 59.0 8.7 2e-05 24.3 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO23194.1 - 2.7e-16 58.5 15.3 5.8e-05 23.3 0.0 8.6 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO23194.1 - 4.5e-16 58.9 12.1 2.2e-05 24.6 0.1 6.3 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO23194.1 - 7.4e-13 47.2 4.7 0.047 13.4 0.0 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO23194.1 - 7.9e-10 38.5 13.6 0.084 13.3 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGO23194.1 - 8.3e-10 38.3 12.8 0.0009 19.0 0.0 6.5 4 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO23194.1 - 1.1e-09 38.2 9.2 0.0037 17.3 0.1 5.3 3 2 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EGO23194.1 - 0.00022 21.0 9.2 4.6 7.3 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 EGO23194.1 - 0.00044 20.0 7.8 1.8 8.4 0.0 5.6 3 2 2 5 5 5 1 Domain of Unknown Function (DUF3856) Apc5 PF12862.2 EGO23194.1 - 0.0048 16.7 1.7 0.31 10.9 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 EGO23194.1 - 0.014 15.4 8.3 0.42 10.7 0.1 5.5 4 1 1 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 EGO23194.1 - 0.041 13.7 7.7 6.4 6.7 0.4 4.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EGO23194.1 - 0.1 12.4 1.4 12 5.8 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.4 EGO23194.1 - 0.27 11.0 1.9 55 3.6 0.0 4.3 3 2 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region SHNi-TPR PF10516.4 EGO23194.1 - 5.4 6.3 6.9 14 5.0 0.2 3.8 4 0 0 4 4 4 0 SHNi-TPR Diphthamide_syn PF01866.12 EGO23195.1 - 1.1e-67 228.4 0.0 2.6e-67 227.2 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein EOS1 PF12326.3 EGO23196.1 - 2.4e-13 50.0 0.4 6.4e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 N-glycosylation protein V_ATPase_I PF01496.14 EGO23198.1 - 0.0035 15.3 0.3 0.005 14.7 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3150 PF11348.3 EGO23198.1 - 0.015 14.4 0.6 0.033 13.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) Tektin PF03148.9 EGO23198.1 - 0.091 11.2 2.0 0.14 10.6 1.4 1.2 1 0 0 1 1 1 0 Tektin family FAD_binding_4 PF01565.18 EGO23200.1 - 1.7e-18 66.4 2.9 3.1e-18 65.5 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO23200.1 - 1.1e-06 28.4 1.2 1.5e-05 24.7 0.1 3.0 3 0 0 3 3 3 1 Berberine and berberine like BSP PF04450.7 EGO23201.1 - 5e-64 215.5 0.0 5.7e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EGO23201.1 - 1.3e-06 28.4 0.0 4.1e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EGO23201.1 - 0.0021 17.7 0.1 0.0034 17.0 0.1 1.3 1 0 0 1 1 1 1 SprT-like family 2OG-FeII_Oxy_2 PF13532.1 EGO23202.1 - 1.7e-23 83.5 0.0 2.2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGO23202.1 - 5.3e-05 23.4 0.1 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rad60-SLD PF11976.3 EGO23203.1 - 8.4e-24 83.0 0.3 1.1e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGO23203.1 - 9.5e-11 40.9 0.0 1.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 EGO23205.1 - 1.1e-14 54.2 0.0 1.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23205.1 - 2.8e-09 36.4 0.0 3.5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGO23205.1 - 0.0066 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain PH_5 PF15405.1 EGO23205.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain p450 PF00067.17 EGO23206.1 - 3.6e-61 207.1 0.0 6.5e-61 206.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EGO23206.1 - 0.027 14.0 0.7 0.3 10.6 0.2 2.4 2 0 0 2 2 2 0 Reticulon RicinB_lectin_2 PF14200.1 EGO23207.1 - 1.3e-25 89.8 0.2 4.2e-17 62.4 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EGO23207.1 - 2.2e-05 24.4 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain FRG1 PF06229.7 EGO23207.1 - 0.0085 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 FRG1-like family Glyco_hydro_30 PF02055.11 EGO23210.1 - 9.6e-25 86.7 1.3 1.4e-24 86.2 0.9 1.3 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Trp_oprn_chp PF09534.5 EGO23213.1 - 0.0061 16.1 0.8 0.0097 15.5 0.6 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF973 PF06157.6 EGO23213.1 - 0.11 11.4 0.6 0.2 10.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) zf-CCHC_3 PF13917.1 EGO23215.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO23215.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO23215.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Thiolase_N PF00108.18 EGO23217.1 - 1.2e-69 234.2 0.2 1.7e-69 233.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO23217.1 - 5.3e-46 155.0 0.2 1.4e-45 153.6 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGO23217.1 - 6.4e-05 22.5 0.2 0.0043 16.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGO23217.1 - 0.002 17.6 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EGO23217.1 - 0.096 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal gag-asp_proteas PF13975.1 EGO23218.1 - 7.4e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO23218.1 - 0.00025 21.4 0.0 0.00078 19.8 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 EGO23218.1 - 0.0052 16.7 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 EGO23221.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO23221.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO23221.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4524 PF15025.1 EGO23222.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) Tropomyosin_1 PF12718.2 EGO23223.1 - 0.031 14.1 1.4 0.069 12.9 1.0 1.6 1 1 0 1 1 1 0 Tropomyosin like G-gamma PF00631.17 EGO23224.1 - 0.048 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 GGL domain THDPS_N_2 PF14805.1 EGO23226.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal p450 PF00067.17 EGO23228.1 - 1.9e-69 234.4 0.0 2.3e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.1 EGO23229.1 - 1.3e-34 117.9 2.0 2.7e-12 46.8 0.0 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO23229.1 - 1.3e-29 102.3 2.7 2.9e-14 53.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO23229.1 - 1.6e-27 94.8 1.1 3.9e-09 36.4 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGO23229.1 - 4e-27 92.6 0.5 4.1e-09 35.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EGO23229.1 - 8.4e-27 90.5 0.1 1.2e-07 31.2 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat SfsA PF03749.8 EGO23229.1 - 0.00063 19.2 0.1 0.41 10.0 0.0 2.1 1 1 1 2 2 2 2 Sugar fermentation stimulation protein Nitro_FeMo-Co PF02579.12 EGO23229.1 - 0.0044 17.0 0.1 2.1 8.4 0.0 2.7 1 1 1 3 3 3 2 Dinitrogenase iron-molybdenum cofactor DUF1450 PF07293.6 EGO23229.1 - 0.17 11.8 2.2 11 6.0 0.0 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF1450) OCD_Mu_crystall PF02423.10 EGO23230.1 - 7.7e-36 123.4 2.3 9.1e-20 70.6 0.1 2.3 1 1 1 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family p450 PF00067.17 EGO23231.1 - 1e-11 44.0 0.0 1e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.10 EGO23231.1 - 0.016 14.7 1.5 0.32 10.5 0.6 2.5 2 1 0 2 2 2 0 Ataxin-2 C-terminal region Peptidase_S49_N PF08496.5 EGO23232.1 - 1.2 8.9 6.1 1.3 8.7 4.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal p450 PF00067.17 EGO23234.1 - 5.6e-58 196.5 0.0 6.8e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Surp PF01805.15 EGO23235.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Surp module Peptidase_M48 PF01435.13 EGO23236.1 - 7.6e-45 153.2 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EGO23236.1 - 0.0027 16.7 0.2 0.0051 15.8 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 AMP-binding PF00501.23 EGO23238.1 - 6.2e-80 268.6 0.0 8.5e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGO23238.1 - 2.6e-15 56.0 0.0 5.7e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Condensation domain Methyltransf_31 PF13847.1 EGO23238.1 - 4.1e-12 45.9 0.0 6.5e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23238.1 - 1.6e-11 44.7 0.1 1.3e-10 41.8 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EGO23238.1 - 3.6e-10 39.9 0.0 2.1e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGO23238.1 - 4.2e-10 40.4 0.0 0.00012 22.9 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.7 EGO23238.1 - 9.3e-10 38.8 0.0 5.3e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23238.1 - 1.7e-09 38.0 0.0 8.4e-09 35.8 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23238.1 - 2.5e-09 37.0 0.0 7.1e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23238.1 - 2.6e-09 37.1 0.0 2.4e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23238.1 - 7e-09 35.9 0.0 2.6e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO23238.1 - 3.9e-08 32.8 0.0 1.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 EGO23238.1 - 4.1e-06 26.3 0.0 9.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 EGO23238.1 - 2.3e-05 23.8 0.0 4.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 EGO23238.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 EGO23238.1 - 0.0054 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 EGO23238.1 - 0.016 14.6 0.0 0.043 13.1 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Phage_CI_repr PF07022.8 EGO23238.1 - 0.063 13.3 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Ubie_methyltran PF01209.13 EGO23238.1 - 0.076 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EGO23238.1 - 0.2 11.1 0.0 0.47 9.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase PADR1 PF08063.7 EGO23239.1 - 0.16 11.3 0.8 0.22 10.9 0.5 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain Peptidase_S28 PF05577.7 EGO23240.1 - 0.011 14.3 0.0 0.26 9.8 0.0 2.0 1 1 1 2 2 2 0 Serine carboxypeptidase S28 TPR_18 PF13512.1 EGO23240.1 - 0.14 12.1 0.4 1.8 8.5 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat ATG22 PF11700.3 EGO23241.1 - 7.2e-151 502.8 10.9 8.9e-151 502.6 7.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGO23241.1 - 6.1e-11 41.6 41.8 6.2e-06 25.1 3.0 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily CAF1-p150_C2 PF15539.1 EGO23241.1 - 0.013 14.6 0.1 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term MFS_1_like PF12832.2 EGO23241.1 - 0.034 13.9 9.1 3.2 7.5 0.1 4.3 4 0 0 4 4 4 0 MFS_1 like family p450 PF00067.17 EGO23242.1 - 3.2e-69 233.6 0.0 3.8e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rad60-SLD PF11976.3 EGO23243.1 - 3.7e-10 39.3 0.1 4.9e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGO23243.1 - 0.00047 19.5 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.19 EGO23243.1 - 0.024 14.2 1.0 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 PB1 domain Rad60-SLD PF11976.3 EGO23244.1 - 1.7e-12 46.8 0.0 2.1e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGO23244.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 EGO23244.1 - 0.0035 17.2 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 GLUT4 regulating protein TUG F-box-like PF12937.2 EGO23245.1 - 0.00016 21.3 0.0 0.00046 19.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like Prenyltrans PF00432.16 EGO23246.1 - 1.6e-32 110.6 12.6 1.1e-07 31.2 0.4 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO23246.1 - 1e-21 77.4 0.0 1e-17 64.5 0.0 3.3 2 2 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO23246.1 - 9.4e-06 25.6 0.0 0.00019 21.3 0.0 2.7 2 1 1 3 3 3 1 Prenyltransferase-like Saccharop_dh PF03435.13 EGO23247.1 - 2.2e-109 366.0 0.3 6e-109 364.5 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EGO23247.1 - 1.1e-91 306.1 0.0 2.7e-91 304.8 0.0 1.6 2 0 0 2 2 2 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 EGO23247.1 - 5.8e-07 29.6 0.1 2.7e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EGO23247.1 - 3.6e-05 24.3 0.0 0.00019 22.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO23247.1 - 0.0056 17.1 0.1 0.077 13.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGO23247.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EGO23247.1 - 0.097 13.1 0.0 2.2 8.8 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain DREV PF05219.7 EGO23247.1 - 0.17 10.7 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase HMG_box PF00505.14 EGO23249.1 - 3.9e-16 59.0 2.7 6.4e-16 58.3 1.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO23249.1 - 1.1e-06 28.8 0.7 1.8e-06 28.2 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EGO23249.1 - 0.047 13.4 0.9 0.069 12.9 0.6 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Peptidase_M61 PF05299.7 EGO23249.1 - 0.047 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 M61 glycyl aminopeptidase Sugar_tr PF00083.19 EGO23252.1 - 2.1e-111 372.6 24.9 2.5e-111 372.4 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO23252.1 - 1.7e-22 79.6 30.8 1.7e-22 79.6 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EGO23253.1 - 2.4e-44 151.2 0.0 3.1e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_31 PF13847.1 EGO23253.1 - 0.0045 16.5 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO23253.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGO23253.1 - 0.024 15.1 0.0 0.078 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EGO23253.1 - 0.04 12.9 0.0 0.097 11.7 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGO23253.1 - 0.066 12.9 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 EGO23253.1 - 0.18 11.2 0.0 0.44 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aldo_ket_red PF00248.16 EGO23254.1 - 9.5e-48 162.4 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 EGO23255.1 - 6.2e-68 229.0 0.0 3.3e-48 164.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EGO23255.1 - 6.4e-14 51.9 0.0 4.3e-12 46.1 0.0 3.2 3 0 0 3 3 3 1 Phosphopantetheine attachment site Condensation PF00668.15 EGO23255.1 - 9.7e-13 47.6 0.1 2.2e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Condensation domain Methyltransf_31 PF13847.1 EGO23255.1 - 9.5e-12 44.7 0.0 2.1e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23255.1 - 3.1e-11 43.8 0.0 1.2e-10 41.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 EGO23255.1 - 1.6e-09 38.5 0.4 0.00012 22.9 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_11 PF08241.7 EGO23255.1 - 7.5e-09 35.9 0.0 7.1e-08 32.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO23255.1 - 1.7e-08 34.8 0.0 5.3e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23255.1 - 4.7e-08 33.3 0.0 2.1e-07 31.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23255.1 - 5.3e-08 32.9 0.0 2.3e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23255.1 - 1.7e-07 31.1 0.0 4.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO23255.1 - 3.1e-06 26.6 0.0 7.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.3 EGO23255.1 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 EGO23255.1 - 0.0069 15.7 0.1 0.019 14.3 0.1 1.7 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EGO23255.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 EGO23255.1 - 0.008 15.5 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EGO23255.1 - 0.02 14.3 0.1 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EGO23255.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.13 EGO23255.1 - 0.03 13.6 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EGO23255.1 - 0.033 13.3 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TatD_DNase PF01026.16 EGO23256.1 - 1.1e-38 132.9 0.1 1.3e-38 132.6 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Ank_3 PF13606.1 EGO23256.1 - 0.11 12.7 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat BTB PF00651.26 EGO23259.1 - 0.0039 17.1 0.0 0.017 15.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Solute_trans_a PF03619.11 EGO23262.1 - 4.3e-71 239.4 15.9 5.1e-71 239.1 11.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glycos_transf_4 PF00953.16 EGO23262.1 - 1.1 8.9 8.1 0.19 11.5 1.5 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 4 DUF4448 PF14610.1 EGO23263.1 - 2.1e-09 37.1 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EGO23263.1 - 0.0005 20.5 3.4 0.0011 19.4 2.4 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UQ_con PF00179.21 EGO23264.1 - 1.7e-07 30.7 0.1 5.7e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_A PF14457.1 EGO23264.1 - 0.0029 17.1 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family A Prok-E2_B PF14461.1 EGO23264.1 - 0.13 12.0 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B Acid_PPase PF12689.2 EGO23265.1 - 3.2e-58 196.0 0.0 3.7e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EGO23265.1 - 0.047 13.9 0.7 0.81 9.8 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EGO23265.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EGO23265.1 - 0.13 12.6 0.3 1 9.7 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase OPT PF03169.10 EGO23267.1 - 1.7e-129 433.1 54.7 3.2e-90 303.3 24.2 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein rve PF00665.21 EGO23268.1 - 4.3e-07 30.0 0.0 8.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SnoaL_2 PF12680.2 EGO23268.1 - 6.9e-05 23.1 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGO23268.1 - 0.0025 17.4 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DDE_3 PF13358.1 EGO23268.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF4440 PF14534.1 EGO23268.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) p450 PF00067.17 EGO23270.1 - 3.7e-28 98.2 0.0 5.4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO23271.1 - 1e-63 215.5 0.0 1.4e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO23273.1 - 6.3e-23 81.0 0.0 7e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dpoe2NT PF12213.3 EGO23274.1 - 0.092 12.6 0.5 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal Retrotrans_gag PF03732.12 EGO23275.1 - 8.1e-09 35.4 0.3 8.1e-09 35.4 0.2 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO23275.1 - 1.5e-08 34.1 4.0 2.7e-08 33.3 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO23275.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO23275.1 - 0.82 9.4 8.7 0.076 12.7 2.1 2.1 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO23276.1 - 5.4e-08 32.7 0.1 5.4e-08 32.7 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO23277.1 - 5e-06 26.1 1.4 8.5e-06 25.4 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO23277.1 - 0.016 14.9 0.3 0.028 14.1 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_4 PF07993.7 EGO23278.1 - 1.4e-49 168.3 0.0 2.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGO23278.1 - 4.7e-09 36.3 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGO23278.1 - 3e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO23278.1 - 0.00015 20.5 0.1 0.00042 19.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO23278.1 - 0.081 12.9 0.0 7.4 6.5 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding AMP-binding_C PF13193.1 EGO23279.1 - 1.3e-06 29.2 0.0 3.9e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EGO23280.1 - 1.2e-05 23.8 0.0 2.4e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO23280.1 - 0.042 14.7 0.2 0.06 14.3 0.1 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EGO23281.1 - 2.5e-10 39.3 0.0 2.8e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.17 EGO23282.1 - 7.5e-37 126.9 0.0 1.1e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EGO23283.1 - 6.5e-76 255.3 0.0 9.3e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGO23283.1 - 3.6e-14 52.3 0.0 6.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Methyltransf_31 PF13847.1 EGO23283.1 - 4.7e-14 52.2 0.0 1.2e-13 50.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23283.1 - 1.3e-13 51.5 0.0 3.8e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO23283.1 - 9.6e-11 42.0 0.0 4.8e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23283.1 - 2.3e-10 40.7 0.0 5.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23283.1 - 9.4e-10 38.5 0.0 2.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23283.1 - 4.3e-09 36.7 0.0 3.6e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23283.1 - 1e-08 35.0 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 EGO23283.1 - 2.1e-07 31.8 0.0 2.1e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CMAS PF02353.15 EGO23283.1 - 1.1e-06 28.0 0.0 2.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGO23283.1 - 3e-06 26.7 0.0 5.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PP-binding PF00550.20 EGO23283.1 - 1.8e-05 24.8 0.0 8.4e-05 22.7 0.0 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_4 PF02390.12 EGO23283.1 - 0.0023 17.0 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_20 PF12147.3 EGO23283.1 - 0.0038 16.1 0.0 0.0066 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 EGO23283.1 - 0.0039 16.6 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.6 EGO23283.1 - 0.0062 15.2 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.15 EGO23283.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EGO23283.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGO23283.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EGO23283.1 - 0.019 14.3 0.1 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EGO23283.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.10 EGO23283.1 - 0.21 11.0 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase HTH_23 PF13384.1 EGO23284.1 - 0.059 13.0 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Aldo_ket_red PF00248.16 EGO23286.1 - 1.2e-71 240.8 0.0 1.4e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 EGO23287.1 - 4.5e-80 269.0 0.0 6.7e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGO23287.1 - 4.3e-16 58.6 0.1 6.5e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 Condensation domain Methyltransf_18 PF12847.2 EGO23287.1 - 7.3e-14 52.3 0.0 2.3e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO23287.1 - 1.9e-10 41.1 0.0 9.6e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain AMP-binding_C PF13193.1 EGO23287.1 - 2e-10 41.4 0.1 4.3e-05 24.3 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 EGO23287.1 - 2.2e-10 40.3 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23287.1 - 2e-09 37.3 0.0 4.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23287.1 - 3e-09 37.2 0.0 9.5e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23287.1 - 1.1e-08 35.3 0.0 4.4e-08 33.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23287.1 - 1.1e-08 35.0 0.0 3.3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGO23287.1 - 1.8e-07 31.3 0.0 1.3e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site MTS PF05175.9 EGO23287.1 - 1.3e-05 24.6 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGO23287.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EGO23287.1 - 0.0013 18.1 0.1 0.0047 16.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_4 PF02390.12 EGO23287.1 - 0.0023 17.0 0.0 0.0044 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CheR PF01739.13 EGO23287.1 - 0.013 14.8 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MetW PF07021.7 EGO23287.1 - 0.022 14.1 0.0 0.06 12.7 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.6 EGO23287.1 - 0.024 14.0 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) p450 PF00067.17 EGO23288.1 - 6.7e-36 123.7 0.0 9.6e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1097 PF06496.6 EGO23288.1 - 0.0067 16.2 0.6 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1097) p450 PF00067.17 EGO23289.1 - 1.1e-43 149.4 0.0 1.3e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EGO23290.1 - 6.4e-18 64.9 0.0 1.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGO23290.1 - 0.048 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Piwi PF02171.12 EGO23293.1 - 8e-77 258.1 0.0 1.2e-76 257.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EGO23293.1 - 1.5e-15 56.6 1.1 3.2e-15 55.6 0.8 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EGO23293.1 - 2.1e-12 46.2 0.0 5.7e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Pyr_redox_3 PF13738.1 EGO23297.1 - 3.3e-18 66.4 0.0 5.9e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO23297.1 - 1.6e-11 43.1 0.0 8.4e-06 24.2 0.0 2.7 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGO23297.1 - 9e-09 35.2 1.6 4.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO23297.1 - 1.2e-08 35.0 0.0 0.013 15.3 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO23297.1 - 4.4e-08 32.4 2.0 4.3e-07 29.1 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGO23297.1 - 6.7e-08 31.8 0.0 6.8e-05 21.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGO23297.1 - 4.2e-06 27.0 1.9 0.011 16.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO23297.1 - 0.00086 18.4 3.4 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO23297.1 - 0.0014 18.4 0.8 0.02 14.6 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EGO23297.1 - 0.0014 18.2 0.1 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EGO23297.1 - 0.0019 17.3 0.1 0.0046 16.0 0.0 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EGO23297.1 - 0.0061 15.4 5.3 0.068 11.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EGO23297.1 - 0.0062 16.1 0.6 0.53 9.8 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EGO23297.1 - 0.013 14.4 5.4 0.065 12.0 0.2 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EGO23297.1 - 0.016 15.2 0.3 2.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EGO23297.1 - 0.018 13.4 4.6 0.13 10.7 0.4 2.3 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EGO23297.1 - 0.05 12.7 0.0 6.2 5.9 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EGO23297.1 - 0.095 12.9 0.1 2.3 8.5 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 EGO23297.1 - 0.1 11.6 1.2 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_10 PF13460.1 EGO23297.1 - 0.64 9.9 3.0 1 9.3 0.3 2.3 2 0 0 2 2 2 0 NADH(P)-binding Glyco_hydro_18 PF00704.23 EGO23298.1 - 1.7e-09 37.5 1.6 2.5e-09 37.0 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mito_carr PF00153.22 EGO23299.1 - 2.3e-21 75.3 8.4 4.4e-09 35.9 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CSL PF05207.8 EGO23300.1 - 3.1e-25 87.4 0.8 3.6e-25 87.2 0.6 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EGO23300.1 - 0.0072 16.2 1.0 0.012 15.5 0.7 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EGO23300.1 - 0.012 15.2 0.3 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGO23300.1 - 0.032 13.9 0.4 0.047 13.3 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.1 EGO23300.1 - 0.073 12.6 1.8 0.14 11.7 1.3 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain GAGA PF09237.6 EGO23300.1 - 0.075 12.6 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 GAGA factor Dicty_CTDC PF00526.13 EGO23300.1 - 1.3 8.9 3.9 9 6.2 0.1 2.2 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat GIDA PF01134.17 EGO23301.1 - 7.1e-156 518.9 0.0 8.6e-156 518.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGO23301.1 - 2.1e-16 59.7 0.0 7.9e-16 57.8 0.0 2.0 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 EGO23301.1 - 1.5e-09 37.5 0.5 3.5e-09 36.2 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO23301.1 - 6.6e-07 29.4 0.0 2.7e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO23301.1 - 4.1e-05 22.6 1.8 0.033 13.0 0.3 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO23301.1 - 0.00012 21.0 0.9 0.00025 20.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO23301.1 - 0.00069 18.1 0.2 0.034 12.6 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EGO23301.1 - 0.0071 16.7 0.1 0.033 14.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO23301.1 - 0.042 12.9 0.2 0.086 11.8 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EGO23301.1 - 0.049 12.5 0.3 6.1 5.6 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2470 PF10615.4 EGO23302.1 - 1.1e-13 51.1 0.1 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 EGO23302.1 - 7e-06 25.8 0.5 1.3e-05 25.0 0.1 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4499) DIM1 PF02966.11 EGO23303.1 - 2.9e-69 230.7 0.1 3.3e-69 230.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EGO23303.1 - 2.7e-05 23.7 0.1 3.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EGO23303.1 - 0.017 15.1 0.1 0.035 14.1 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.1 EGO23303.1 - 0.023 14.7 0.2 0.033 14.3 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.10 EGO23303.1 - 0.027 14.1 0.3 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 TFIIS_M PF07500.9 EGO23304.1 - 2e-31 108.4 0.9 1.9e-30 105.2 0.0 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGO23304.1 - 2.8e-18 65.2 9.7 4.6e-18 64.5 6.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGO23304.1 - 1.2e-12 47.0 2.4 2e-12 46.4 0.5 2.0 1 1 1 2 2 2 1 TFIIS helical bundle-like domain DUF3216 PF11505.3 EGO23304.1 - 0.056 13.2 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) WD40 PF00400.27 EGO23305.1 - 3.6e-52 172.4 15.7 5.4e-09 35.5 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO23305.1 - 0.00086 17.5 0.5 1.9 6.5 0.1 3.9 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO23305.1 - 0.0064 15.2 0.0 0.49 9.0 0.0 2.3 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EGO23305.1 - 0.083 12.3 0.4 3.6 6.9 0.0 2.7 1 1 0 2 2 2 0 PQQ-like domain NAD_binding_4 PF07993.7 EGO23306.1 - 3.3e-35 121.2 0.0 4.9e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO23306.1 - 9.1e-18 63.8 0.0 2.2e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EGO23306.1 - 2.6e-13 49.9 0.0 4.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO23306.1 - 6.8e-08 32.7 0.0 9e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EGO23306.1 - 1.7e-05 24.8 0.0 4.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO23306.1 - 5.5e-05 22.0 0.0 0.0001 21.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EGO23306.1 - 0.00034 20.3 0.2 0.0012 18.5 0.2 2.0 1 1 0 1 1 1 1 KR domain AA_permease_2 PF13520.1 EGO23307.1 - 1.2e-71 241.5 44.9 1.5e-71 241.2 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO23307.1 - 3.3e-19 68.5 39.6 4.8e-19 68.0 27.4 1.2 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.2 EGO23308.1 - 3.5e-06 26.6 0.7 1e-05 25.1 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO23308.1 - 0.014 15.0 2.8 0.014 15.0 2.0 2.0 2 0 0 2 2 2 0 F-box domain Capsid-VNN PF11729.3 EGO23308.1 - 0.037 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 nodavirus capsid protein C2 PF00168.25 EGO23309.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.18 EGO23312.1 - 1.7e-66 224.0 0.0 6.2e-66 222.2 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO23312.1 - 9.6e-16 57.4 0.0 4.9e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO23312.1 - 3.7e-07 30.1 0.0 1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGO23312.1 - 2e-05 23.5 0.0 6.7e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ITAM PF02189.10 EGO23312.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Terpene_synth_C PF03936.11 EGO23313.1 - 1.6e-09 37.4 0.1 2.5e-09 36.7 0.1 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Phosphodiest PF01663.17 EGO23316.1 - 2.4e-08 33.6 0.3 2.4e-08 33.6 0.2 1.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGO23316.1 - 0.013 14.6 0.0 0.03 13.4 0.0 1.7 1 1 0 1 1 1 0 Sulfatase Metalloenzyme PF01676.13 EGO23316.1 - 0.38 10.1 0.3 0.62 9.3 0.2 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily ubiquitin PF00240.18 EGO23317.1 - 0.049 13.0 0.1 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF1462 PF07315.6 EGO23317.1 - 0.067 13.1 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Pkinase PF00069.20 EGO23318.1 - 3.3e-06 26.4 0.0 5.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGO23318.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO23318.1 - 0.002 17.9 0.1 0.0044 16.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGO23318.1 - 0.0028 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO23318.1 - 0.025 13.9 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 EGO23318.1 - 0.083 12.0 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase DUF2791 PF10923.3 EGO23320.1 - 0.01 14.4 0.5 0.016 13.8 0.3 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Ssl1 PF04056.9 EGO23323.1 - 0.069 12.7 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Ssl1-like ABC_membrane PF00664.18 EGO23327.1 - 3.6e-54 184.0 38.5 6.8e-28 97.8 9.1 2.9 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO23327.1 - 1e-49 168.3 0.0 4.4e-27 95.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO23327.1 - 6.3e-08 32.9 0.4 0.19 11.6 0.0 3.7 3 1 1 4 4 3 3 AAA domain SMC_N PF02463.14 EGO23327.1 - 1.3e-06 27.8 2.2 0.0018 17.5 0.9 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO23327.1 - 8.2e-06 26.2 1.7 0.052 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGO23327.1 - 8.6e-06 25.2 0.1 0.083 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGO23327.1 - 2.1e-05 25.0 0.3 0.089 13.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EGO23327.1 - 4.1e-05 23.6 0.0 0.066 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGO23327.1 - 4.8e-05 22.7 2.1 0.1 12.1 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGO23327.1 - 5.2e-05 23.1 0.6 0.065 13.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EGO23327.1 - 0.00018 20.7 0.1 0.51 9.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EGO23327.1 - 0.00021 20.8 0.4 0.058 12.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EGO23327.1 - 0.00089 20.0 0.1 0.18 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO23327.1 - 0.0049 17.0 2.9 7 6.8 0.1 4.2 4 0 0 4 4 4 0 AAA domain UPF0079 PF02367.12 EGO23327.1 - 0.0069 16.0 1.3 0.15 11.6 0.0 3.1 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EGO23327.1 - 0.0082 15.6 0.4 0.57 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EGO23327.1 - 0.0091 15.1 1.5 3 6.9 0.2 2.3 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EGO23327.1 - 0.03 14.1 1.3 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 EGO23327.1 - 0.061 11.9 2.0 2.6 6.5 0.1 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EGO23327.1 - 0.12 11.8 2.4 14 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGO23327.1 - 0.14 12.4 0.2 22 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EGO23327.1 - 0.17 11.6 0.7 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EGO23327.1 - 0.18 11.2 1.5 0.93 8.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EGO23327.1 - 0.2 11.4 2.0 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EGO23327.1 - 0.41 10.3 2.2 0.77 9.4 0.2 2.2 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 EGO23327.1 - 0.5 9.8 3.3 41 3.6 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 EGO23327.1 - 0.54 9.2 0.1 30 3.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FAD_binding_3 PF01494.14 EGO23328.1 - 1.5e-20 73.5 0.0 1.2e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO23328.1 - 0.034 14.1 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 EGO23329.1 - 4.3e-63 213.4 0.0 5.2e-42 143.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Retrotrans_gag PF03732.12 EGO23330.1 - 5.5e-09 35.9 0.3 5.5e-09 35.9 0.2 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein BMFP PF04380.8 EGO23330.1 - 0.22 11.6 1.3 28 4.9 0.2 3.3 3 0 0 3 3 3 0 Membrane fusogenic activity zf-C2H2 PF00096.21 EGO23334.1 - 0.027 14.8 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Myb_DNA-bind_3 PF12776.2 EGO23335.1 - 2.3e-11 44.1 0.0 3.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain GP120 PF00516.13 EGO23335.1 - 0.017 13.3 0.0 0.021 13.0 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 HTH_23 PF13384.1 EGO23336.1 - 1.8e-07 30.5 0.1 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGO23336.1 - 0.0024 17.8 0.1 0.0045 16.9 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGO23336.1 - 0.031 13.6 0.1 0.055 12.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.2 EGO23336.1 - 0.032 14.4 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 EGO23336.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_29 PF13551.1 EGO23336.1 - 0.082 13.0 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix p450 PF00067.17 EGO23337.1 - 1.3e-70 238.2 0.0 1.8e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO23338.1 - 1.7e-15 56.5 0.0 1.8e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase-like PF12876.2 EGO23338.1 - 0.051 14.0 0.0 0.07 13.5 0.0 1.4 1 1 1 2 2 2 0 Sugar-binding cellulase-like Zip PF02535.17 EGO23339.1 - 4e-18 65.4 12.6 1.2e-11 44.1 2.4 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Cellulase PF00150.13 EGO23340.1 - 5.4e-50 170.1 0.0 6.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EGO23340.1 - 1.8e-13 49.8 6.7 1.1e-12 47.3 4.6 2.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Aldedh PF00171.17 EGO23341.1 - 4.2e-178 592.4 0.1 5e-178 592.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO23341.1 - 0.00056 18.7 0.0 0.0013 17.5 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) WSC PF01822.14 EGO23342.1 - 4.5e-72 238.0 61.3 3.2e-19 68.6 7.3 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 EGO23342.1 - 5.8e-29 100.8 0.1 2.2e-26 92.4 0.0 3.3 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGO23342.1 - 1.7e-18 66.5 0.0 4.3e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 EGO23342.1 - 0.052 13.3 0.9 1.4 8.8 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Hydrophobin PF01185.13 EGO23343.1 - 1.5e-20 73.3 5.7 1.9e-20 73.0 4.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CBF PF03914.12 EGO23344.1 - 7.7e-30 103.5 0.0 7.7e-30 103.5 0.0 2.8 3 0 0 3 3 3 1 CBF/Mak21 family AhpC-TSA PF00578.16 EGO23345.1 - 1.3e-39 134.7 0.0 1.7e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO23345.1 - 1.1e-16 60.6 0.0 1.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EGO23345.1 - 3.3e-11 42.6 0.0 5.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AAA PF00004.24 EGO23346.1 - 9.5e-74 245.8 0.0 2.2e-40 137.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO23346.1 - 1.2e-11 44.1 0.0 0.00038 19.5 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGO23346.1 - 3.1e-11 43.1 0.0 1.5e-05 24.7 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO23346.1 - 1.2e-10 41.6 1.3 3.4e-05 23.9 0.1 3.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EGO23346.1 - 1.5e-09 38.0 0.0 0.00014 21.9 0.0 4.3 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO23346.1 - 1.8e-08 34.4 0.0 0.00066 19.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGO23346.1 - 3.1e-08 33.2 0.0 0.00023 20.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO23346.1 - 6.2e-08 31.9 0.0 0.00011 21.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EGO23346.1 - 7.1e-08 32.4 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGO23346.1 - 1.1e-07 30.9 0.0 0.0022 16.8 0.0 2.4 3 0 0 3 3 2 2 TIP49 C-terminus AAA_33 PF13671.1 EGO23346.1 - 1.6e-07 31.2 0.0 0.00015 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO23346.1 - 6e-07 29.1 0.3 0.00096 18.8 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EGO23346.1 - 7.3e-07 30.0 0.0 0.00011 23.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGO23346.1 - 3.1e-06 26.7 0.9 0.42 9.9 0.0 3.8 2 2 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 EGO23346.1 - 0.00012 22.1 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EGO23346.1 - 0.00024 20.3 0.3 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGO23346.1 - 0.00038 20.5 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EGO23346.1 - 0.00054 19.9 0.0 0.072 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGO23346.1 - 0.00074 19.2 0.0 0.089 12.4 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_18 PF13238.1 EGO23346.1 - 0.0019 18.4 0.0 0.0064 16.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain DAP3 PF10236.4 EGO23346.1 - 0.0023 16.9 0.0 0.0093 14.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 EGO23346.1 - 0.0036 16.8 0.0 0.025 14.0 0.0 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EGO23346.1 - 0.0042 16.7 0.0 0.058 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGO23346.1 - 0.0047 16.5 0.0 0.9 9.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EGO23346.1 - 0.005 16.3 0.0 0.22 11.0 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EGO23346.1 - 0.0062 15.7 0.0 0.5 9.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 EGO23346.1 - 0.0063 16.0 0.0 0.89 9.0 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EGO23346.1 - 0.01 15.4 0.0 0.58 9.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EGO23346.1 - 0.01 16.1 0.0 0.27 11.5 0.0 2.8 3 1 0 3 3 2 0 ABC transporter AAA_24 PF13479.1 EGO23346.1 - 0.016 14.8 0.1 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO23346.1 - 0.022 14.4 0.0 10 5.7 0.0 3.5 2 2 2 4 4 4 0 Archaeal ATPase KaiC PF06745.8 EGO23346.1 - 0.026 13.6 0.0 3.8 6.5 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.1 EGO23346.1 - 0.035 13.6 0.0 0.58 9.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 EGO23346.1 - 0.06 12.1 0.0 3.4 6.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 EGO23346.1 - 0.064 12.1 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EGO23346.1 - 0.067 12.8 0.0 0.56 9.8 0.0 2.4 3 0 0 3 3 2 0 Bacterial dnaA protein Rad17 PF03215.10 EGO23346.1 - 0.096 11.3 0.0 2.6 6.6 0.0 2.4 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EGO23346.1 - 0.12 12.0 0.2 2.3 7.8 0.0 2.9 2 2 0 3 3 3 0 NTPase F1F0-ATPsyn_F PF10791.4 EGO23350.1 - 5.3e-27 93.8 0.0 6.2e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EGO23350.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Abi PF02517.11 EGO23351.1 - 1e-15 57.5 4.4 1e-15 57.5 3.0 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity MFS_1 PF07690.11 EGO23354.1 - 1e-18 67.1 26.1 1.1e-18 67.0 18.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM173 PF15009.1 EGO23354.1 - 0.11 11.2 0.2 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 EB1 PF03271.12 EGO23355.1 - 4.6e-16 58.5 2.4 9.8e-16 57.5 1.7 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EGO23355.1 - 4.5e-07 29.8 0.5 7.7e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.3 EGO23355.1 - 0.038 13.7 1.2 0.11 12.2 0.8 1.8 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Matrilin_ccoil PF10393.4 EGO23355.1 - 0.074 12.4 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Mito_fiss_reg PF05308.6 EGO23356.1 - 9.6 5.4 8.6 12 5.1 6.0 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator Ras PF00071.17 EGO23359.1 - 1.2e-54 184.0 0.0 1.4e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO23359.1 - 1.3e-15 57.9 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO23359.1 - 9.4e-07 28.2 0.0 1.7e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO23359.1 - 0.0027 16.9 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGO23359.1 - 0.054 12.6 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGO23359.1 - 0.074 12.5 0.0 11 5.4 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AKAP7_NLS PF10469.4 EGO23360.1 - 3.9e-27 95.3 0.0 1.4e-26 93.4 0.0 1.9 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Asp PF00026.18 EGO23361.1 - 1e-34 120.2 0.0 3.3e-34 118.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO23361.1 - 3e-07 30.5 1.6 7.3e-07 29.2 0.5 2.0 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Sugar_tr PF00083.19 EGO23362.1 - 1.2e-47 162.4 17.8 1.7e-47 162.0 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO23362.1 - 2.6e-22 79.0 23.6 3.1e-16 59.0 1.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_15 PF00723.16 EGO23364.1 - 5.5e-53 180.1 0.0 8.7e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Abhydrolase_6 PF12697.2 EGO23365.1 - 5.4e-23 82.0 0.0 6.9e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO23365.1 - 4.3e-16 59.1 0.0 6.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO23365.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO23365.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EGO23365.1 - 0.0095 15.3 0.0 0.035 13.5 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Pneumo_M2 PF07380.6 EGO23365.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus M2 protein Glyco_transf_11 PF01531.11 EGO23366.1 - 0.012 14.6 0.1 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 Pkinase PF00069.20 EGO23369.1 - 2.2e-10 40.1 0.0 2.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO23369.1 - 0.058 13.1 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGO23369.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family zf-CCHC_3 PF13917.1 EGO23371.1 - 1.3e-05 24.8 3.4 2.2e-05 24.0 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO23371.1 - 6.6e-05 22.6 5.5 6.6e-05 22.6 3.8 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO23371.1 - 0.25 10.8 3.6 0.42 10.1 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pkinase PF00069.20 EGO23372.1 - 2.9e-10 39.7 0.0 2.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23372.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EGO23372.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NACHT PF05729.7 EGO23374.1 - 8.1e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO23374.1 - 2.2e-05 24.5 0.0 3.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO23374.1 - 9.8e-05 22.5 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO23374.1 - 0.00023 20.2 0.1 0.00053 19.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EGO23374.1 - 0.0068 17.2 0.1 0.45 11.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO23374.1 - 0.012 15.3 0.0 0.064 13.0 0.0 2.2 2 1 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EGO23374.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.7 2 1 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EGO23374.1 - 0.036 13.1 0.0 0.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 EGO23374.1 - 0.057 13.7 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGO23374.1 - 0.067 12.0 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rhodanese PF00581.15 EGO23374.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Ank PF00023.25 EGO23375.1 - 1.2e-06 28.0 0.0 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGO23375.1 - 6.4e-05 23.2 0.0 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO23375.1 - 0.00041 20.7 0.1 0.024 15.1 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO23375.1 - 0.0036 17.3 0.3 0.05 13.8 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EGO23375.1 - 0.055 13.7 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF4490 PF14892.1 EGO23376.1 - 0.016 14.8 1.1 0.022 14.3 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4490) DUF4061 PF13270.1 EGO23376.1 - 0.051 13.6 0.3 0.07 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Strep_67kDa_ant PF06100.6 EGO23376.1 - 0.12 10.6 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Peptidase_S10 PF00450.17 EGO23378.1 - 5.7e-95 318.9 8.3 7.4e-95 318.5 5.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3602 PF12223.3 EGO23379.1 - 0.0032 17.8 2.6 0.0052 17.1 1.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3602) Thiol-ester_cl PF10569.4 EGO23380.1 - 1.3 8.2 4.5 0.43 9.8 0.6 2.0 2 0 0 2 2 2 0 Alpha-macro-globulin thiol-ester bond-forming region SE PF08491.5 EGO23381.1 - 3e-94 314.9 0.0 3.9e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EGO23381.1 - 2e-10 40.2 0.3 4.2e-09 35.9 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO23381.1 - 1.5e-09 37.2 0.0 0.00076 18.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO23381.1 - 8.7e-05 21.5 2.0 0.038 12.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EGO23381.1 - 0.0016 18.3 0.2 0.0053 16.6 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO23381.1 - 0.0024 16.8 0.0 0.035 13.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO23381.1 - 0.0088 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGO23381.1 - 0.011 14.3 0.7 1.3 7.6 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 EGO23381.1 - 0.027 13.5 0.0 0.062 12.3 0.0 1.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 EGO23381.1 - 0.059 13.1 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EGO23381.1 - 0.11 11.2 0.4 2.3 6.9 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF2304 PF10066.4 EGO23382.1 - 9.2 6.1 12.1 0.11 12.3 1.8 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Complex1_51K PF01512.12 EGO23384.1 - 7.2e-48 162.1 0.0 1e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGO23384.1 - 1.1e-19 69.3 0.8 1.1e-19 69.3 0.6 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGO23384.1 - 2.1e-08 33.9 0.0 1e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 SLBB domain DSPc PF00782.15 EGO23386.1 - 1.7e-28 98.8 0.0 2.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EGO23386.1 - 0.00027 19.9 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EGO23386.1 - 0.066 12.5 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SIR2 PF02146.12 EGO23387.1 - 0.00041 20.1 0.1 0.00088 19.0 0.0 1.6 2 0 0 2 2 2 1 Sir2 family adh_short PF00106.20 EGO23389.1 - 8.8e-16 58.2 0.0 2.6e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO23389.1 - 0.00014 21.6 0.0 0.00033 20.3 0.0 1.7 2 0 0 2 2 2 1 KR domain TPP_enzyme_N PF02776.13 EGO23390.1 - 5e-39 133.5 0.1 1.2e-38 132.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGO23390.1 - 3.2e-12 46.2 0.0 6.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO23390.1 - 3.9e-11 42.8 0.1 1.4e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Arrestin_N PF00339.24 EGO23391.1 - 0.025 14.4 0.0 0.096 12.4 0.0 2.0 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain F-box-like PF12937.2 EGO23392.1 - 1.5e-07 31.0 0.1 5.2e-07 29.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EGO23392.1 - 7.8e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain CBM_5_12 PF02839.9 EGO23393.1 - 3.1e-17 61.8 34.1 2.9e-12 45.9 4.8 3.8 4 0 0 4 4 4 2 Carbohydrate binding domain CBM_5_12_2 PF14600.1 EGO23393.1 - 3.8e-06 26.4 20.3 1.1e-05 24.9 4.4 2.9 2 0 0 2 2 2 2 Cellulose-binding domain Peptidase_S10 PF00450.17 EGO23394.1 - 9.4e-96 321.4 5.5 1.2e-95 321.1 3.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 EGO23394.1 - 0.00025 20.8 0.0 0.00084 19.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FA_desaturase PF00487.19 EGO23396.1 - 2.2e-32 112.5 31.5 4e-32 111.6 21.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGO23396.1 - 5.3e-11 42.1 0.0 1.5e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 2OG-FeII_Oxy PF03171.15 EGO23397.1 - 8.2e-05 22.8 0.0 0.00029 21.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGO23397.1 - 0.0022 18.4 0.1 0.0075 16.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ArfGap PF01412.13 EGO23398.1 - 4.8e-34 116.6 1.1 9.4e-34 115.6 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CytochromB561_N PF09786.4 EGO23398.1 - 0.39 9.1 7.6 0.52 8.6 5.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Clat_adaptor_s PF01217.15 EGO23399.1 - 2.3e-56 189.4 2.8 2.6e-56 189.3 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UTP15_C PF09384.5 EGO23399.1 - 0.036 13.7 0.3 6 6.5 0.1 2.2 1 1 1 2 2 2 0 UTP15 C terminal F-box-like PF12937.2 EGO23400.1 - 0.015 15.0 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 F-box-like CsbD PF05532.7 EGO23402.1 - 3.8e-12 45.6 17.5 5.9e-08 32.2 3.5 2.1 1 1 1 2 2 2 2 CsbD-like Coprogen_oxidas PF01218.13 EGO23403.1 - 4.7e-50 169.8 0.0 1.9e-49 167.8 0.0 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase DUF4381 PF14316.1 EGO23404.1 - 0.046 13.8 0.2 0.046 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4381 PF14316.1 EGO23407.1 - 0.042 13.9 0.2 0.045 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) UQ_con PF00179.21 EGO23408.1 - 8.6e-42 141.8 0.1 1.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EGO23408.1 - 2.2e-19 68.7 0.5 4e-19 67.9 0.4 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EGO23408.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.9 EGO23408.1 - 0.091 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 FeoA domain MSC PF09402.5 EGO23409.1 - 0.053 12.2 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Acetyltransf_1 PF00583.19 EGO23410.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO23410.1 - 0.00025 21.1 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO23410.1 - 0.0031 17.6 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EGO23412.1 - 1.4e-28 99.5 42.6 1.2e-26 93.2 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ammonium_transp PF00909.16 EGO23414.1 - 0.0033 15.9 4.5 0.004 15.6 3.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family TauE PF01925.14 EGO23414.1 - 0.2 11.0 7.5 0.3 10.5 5.2 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE MFS_1 PF07690.11 EGO23414.1 - 1.2 7.8 10.7 1.7 7.2 7.4 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.11 EGO23415.1 - 3.2e-22 78.7 25.5 4.1e-22 78.3 17.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.13 EGO23415.1 - 0.25 9.8 8.4 0.33 9.4 5.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF751 PF05421.6 EGO23415.1 - 2.2 8.6 9.3 4.3 7.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF751) MFS_1 PF07690.11 EGO23416.1 - 1.9e-21 76.1 36.6 1.9e-21 76.1 25.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_3 PF00591.16 EGO23417.1 - 3.3e-60 203.6 0.3 6.9e-46 156.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EGO23417.1 - 1.2e-09 37.6 0.0 5.6e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain HisG PF01634.13 EGO23418.1 - 6.4e-49 165.6 0.1 9.4e-49 165.1 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EGO23418.1 - 2.2e-27 94.7 0.1 5.6e-27 93.4 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EGO23418.1 - 0.00081 19.0 0.1 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like F-box-like PF12937.2 EGO23419.1 - 1.3e-08 34.3 0.4 5.1e-08 32.5 0.3 2.1 1 0 0 1 1 1 1 F-box-like Rot1 PF10681.4 EGO23421.1 - 2.8e-57 193.4 3.2 3.3e-57 193.2 2.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Proteasome PF00227.21 EGO23422.1 - 2.2e-32 111.9 0.0 3.1e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Retrotrans_gag PF03732.12 EGO23425.1 - 3.3e-07 30.2 0.6 4.2e-07 29.9 0.4 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein COG5 PF10392.4 EGO23426.1 - 0.052 13.5 0.6 0.082 12.8 0.4 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SPX PF03105.14 EGO23426.1 - 0.097 12.4 0.9 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 SPX domain AMP-binding PF00501.23 EGO23427.1 - 1.8e-31 109.0 0.0 9.7e-31 106.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO23427.1 - 2.2e-30 105.3 0.0 3.2e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO23427.1 - 2e-09 37.2 0.0 4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGO23427.1 - 0.00015 21.9 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EGO23427.1 - 0.044 13.7 0.0 0.93 9.4 0.0 2.8 2 1 0 2 2 2 0 NADH(P)-binding Lipid_DES PF08557.5 EGO23427.1 - 0.047 12.9 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) 3Beta_HSD PF01073.14 EGO23427.1 - 0.25 9.9 0.0 0.64 8.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Med7 PF05983.6 EGO23430.1 - 3.3e-24 85.4 0.0 4.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 MED7 protein LRR_8 PF13855.1 EGO23432.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Leucine rich repeat Helicase_C PF00271.26 EGO23433.1 - 9.8e-07 28.5 0.0 3.2e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO23433.1 - 2.1e-06 27.3 0.0 8e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EGO23433.1 - 0.0012 17.5 0.0 0.002 16.7 0.0 1.3 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Retrotrans_gag PF03732.12 EGO23434.1 - 2.2e-09 37.2 0.2 2.2e-09 37.2 0.1 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO23434.1 - 2.2e-08 33.6 4.5 4e-08 32.8 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1729 PF08354.5 EGO23434.1 - 0.012 15.4 0.5 0.03 14.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) zf-CCHC_3 PF13917.1 EGO23434.1 - 0.042 13.5 1.5 0.1 12.3 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle HTH_23 PF13384.1 EGO23435.1 - 6.1e-06 25.7 0.0 1e-05 24.9 0.0 1.4 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EGO23435.1 - 0.019 14.3 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.1 EGO23435.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EGO23435.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 NUMOD1 domain F-box-like PF12937.2 EGO23438.1 - 3.2e-08 33.1 0.1 5.2e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGO23439.1 - 0.11 12.1 1.2 0.4 10.3 0.3 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO23439.1 - 0.17 11.6 1.3 1.5 8.6 0.1 2.7 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EGO23439.1 - 0.54 10.4 2.9 4.9 7.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Mmp37 PF09139.6 EGO23441.1 - 3.5e-92 308.9 0.0 4e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 TniQ PF06527.6 EGO23441.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 TniQ COesterase PF00135.23 EGO23442.1 - 1.1e-98 331.3 0.2 4.1e-98 329.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO23442.1 - 0.0054 16.3 0.2 0.033 13.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold APG12 PF04110.8 EGO23442.1 - 0.011 15.8 0.2 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Peptidase_S9 PF00326.16 EGO23442.1 - 0.023 13.8 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DER1 PF04511.10 EGO23443.1 - 2.9e-48 164.0 5.0 3.5e-48 163.7 3.5 1.0 1 0 0 1 1 1 1 Der1-like family HIT PF01230.18 EGO23444.1 - 2.4e-24 85.7 0.1 3.1e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO23444.1 - 6.5e-11 42.4 0.1 9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGO23444.1 - 0.00066 19.3 0.9 0.0014 18.2 0.6 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 COesterase PF00135.23 EGO23445.1 - 1.1e-98 331.2 0.1 1.4e-97 327.7 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO23445.1 - 0.0065 16.0 0.0 0.028 13.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.2 EGO23447.1 - 3.1e-05 23.6 0.1 0.00016 21.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like DUF3251 PF11622.3 EGO23447.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Lipase_3 PF01764.20 EGO23449.1 - 1.8e-07 30.8 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGO23449.1 - 0.045 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EGO23449.1 - 0.1 12.2 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FAD_binding_4 PF01565.18 EGO23450.1 - 1.4e-22 79.6 0.3 2.2e-22 79.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain PARP PF00644.15 EGO23450.1 - 4.5e-09 36.0 0.0 8.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BBE PF08031.7 EGO23450.1 - 0.033 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PARP PF00644.15 EGO23451.1 - 4.5e-09 36.0 0.9 7.2e-08 32.0 0.6 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Aldo_ket_red PF00248.16 EGO23452.1 - 2.7e-53 180.6 0.0 3.5e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Homeobox PF00046.24 EGO23452.1 - 0.015 14.8 0.0 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Homeobox domain P12 PF12669.2 EGO23452.1 - 0.024 14.8 0.2 0.04 14.1 0.2 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF3357 PF11837.3 EGO23452.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SWI-SNF_Ssr4 PF08549.5 EGO23453.1 - 1.5e-11 43.3 0.1 7.3e-09 34.5 0.1 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1750) CG-1 PF03859.11 EGO23453.1 - 0.00036 20.0 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 CG-1 domain Pkinase PF00069.20 EGO23454.1 - 1.1e-32 113.1 0.0 1.1e-31 109.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23454.1 - 9.1e-24 83.9 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.2 EGO23455.1 - 3.3e-06 26.7 0.4 8.3e-06 25.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO23455.1 - 0.00016 21.2 0.9 0.00034 20.1 0.6 1.6 1 0 0 1 1 1 1 F-box domain Chitin_synth_1 PF01644.12 EGO23457.1 - 8.3e-87 289.0 0.1 1.6e-86 288.1 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGO23457.1 - 3.4e-30 103.5 0.0 7.2e-30 102.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGO23457.1 - 1.3e-23 83.1 1.3 2.1e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGO23457.1 - 1.3e-05 25.1 0.0 3.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGO23457.1 - 0.008 15.9 16.1 0.28 10.8 11.1 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 adh_short PF00106.20 EGO23458.1 - 3.8e-20 72.4 1.3 5.1e-20 72.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23458.1 - 5.5e-13 49.2 0.0 1.1e-12 48.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO23458.1 - 1.7e-07 31.4 0.1 3.5e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO23458.1 - 1.7e-06 27.8 0.3 3.4e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EGO23458.1 - 0.0055 15.6 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EGO23458.1 - 0.038 13.7 0.2 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EGO23458.1 - 0.088 12.0 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family F-box-like PF12937.2 EGO23461.1 - 3.4e-06 26.6 1.4 1.1e-05 25.0 1.0 1.9 1 1 0 1 1 1 1 F-box-like Trp_halogenase PF04820.9 EGO23462.1 - 6.5e-06 25.0 0.1 0.23 10.0 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase FAD_oxidored PF12831.2 EGO23462.1 - 8.1e-05 21.8 0.0 0.00018 20.7 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Abhydrolase_6 PF12697.2 EGO23462.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DAO PF01266.19 EGO23462.1 - 0.12 11.2 0.1 0.61 8.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF342 PF03961.8 EGO23463.1 - 0.37 9.1 4.9 0.43 8.9 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mvb12 PF09452.5 EGO23463.1 - 0.45 10.7 2.4 0.89 9.7 0.2 2.2 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Alg6_Alg8 PF03155.10 EGO23465.1 - 8.8e-132 440.2 24.4 1e-102 344.4 8.2 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.17 EGO23467.1 - 2.9e-12 46.5 0.3 4.3e-12 45.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGO23467.1 - 0.0036 17.2 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 EGO23467.1 - 0.033 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily APOBEC_C PF05240.9 EGO23467.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain NACHT PF05729.7 EGO23469.1 - 3.8e-05 23.4 0.1 5.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain Rhodanese PF00581.15 EGO23469.1 - 0.0056 17.0 0.1 0.063 13.6 0.0 2.2 1 1 1 2 2 2 1 Rhodanese-like domain DUF4276 PF14103.1 EGO23469.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Cep57_MT_bd PF06657.8 EGO23469.1 - 0.053 13.4 0.2 0.38 10.7 0.0 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2962 PF11176.3 EGO23469.1 - 0.063 12.8 0.1 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) DNA_pol3_chi PF04364.8 EGO23469.1 - 0.066 13.0 0.9 1.9 8.3 0.0 2.3 1 1 0 2 2 2 0 DNA polymerase III chi subunit, HolC DNA_repr_REX1B PF14966.1 EGO23469.1 - 0.075 13.4 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA repair REX1-B TRI5 PF06330.6 EGO23470.1 - 0.00039 19.1 0.0 0.44 9.1 0.0 2.2 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) Bot1p PF12298.3 EGO23470.1 - 0.1 12.5 0.1 6.7 6.6 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic mitochondrial regulator protein EBV-NA3 PF05009.7 EGO23473.1 - 0.041 13.1 1.8 0.044 13.0 1.2 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TFIIF_alpha PF05793.7 EGO23473.1 - 0.25 9.6 7.9 0.25 9.6 5.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4611 PF15387.1 EGO23473.1 - 0.34 11.0 5.9 0.41 10.8 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.7 EGO23473.1 - 0.4 10.3 7.2 0.41 10.3 5.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EGO23473.1 - 0.92 7.4 6.1 0.88 7.5 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGO23473.1 - 1.3 8.4 6.8 1.6 8.2 4.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin FMN_dh PF01070.13 EGO23474.1 - 7.6e-116 386.8 0.2 9.3e-116 386.5 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGO23474.1 - 1.1e-05 24.4 0.6 0.00053 18.9 0.0 2.7 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EGO23474.1 - 0.00012 21.2 1.0 0.084 11.9 0.0 3.0 3 1 0 4 4 4 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EGO23474.1 - 0.00034 19.6 0.1 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EGO23474.1 - 0.00057 19.1 0.5 0.001 18.3 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.16 EGO23474.1 - 0.066 12.2 0.1 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase tRNA-synt_2e PF02091.10 EGO23474.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit WD40 PF00400.27 EGO23475.1 - 0.0012 18.5 2.1 0.065 13.1 0.0 3.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Glyco_hydro_20 PF00728.17 EGO23476.1 - 1e-83 281.4 0.0 1.2e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGO23476.1 - 1.9e-10 41.5 0.0 3.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGO23476.1 - 0.0003 21.3 0.0 0.00067 20.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 SET PF00856.23 EGO23477.1 - 3.2e-21 76.3 1.1 1.7e-20 73.9 0.7 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EGO23477.1 - 4e-20 72.0 3.3 4e-20 72.0 2.3 1.9 2 1 0 2 2 2 1 Pre-SET motif FA_desaturase PF00487.19 EGO23478.1 - 2.3e-29 102.6 27.3 2.3e-29 102.6 19.0 1.8 2 0 0 2 2 2 1 Fatty acid desaturase SbcCD_C PF13558.1 EGO23479.1 - 1.5e-11 44.0 0.1 6.5e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EGO23479.1 - 6.8e-08 32.8 2.7 7.8e-07 29.3 1.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 EGO23479.1 - 2.2e-05 23.1 36.3 0.0074 14.8 0.1 3.0 1 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EGO23479.1 - 0.0024 17.1 20.0 0.0042 16.3 13.8 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NPV_P10 PF05531.7 EGO23479.1 - 0.069 13.4 16.9 1.6 9.0 0.1 4.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EGO23479.1 - 0.15 11.6 30.5 0.46 10.0 14.0 3.3 1 1 2 3 3 3 0 IncA protein GAS PF13851.1 EGO23479.1 - 0.22 10.6 35.2 0.27 10.3 8.7 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EGO23479.1 - 0.34 10.0 8.9 2.9 7.0 0.1 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF1829 PF08862.5 EGO23479.1 - 0.41 10.9 0.1 0.41 10.9 0.1 3.7 4 1 1 5 5 3 0 Domain of unknown function DUF1829 APG6 PF04111.7 EGO23479.1 - 0.44 9.5 36.9 0.03 13.3 10.5 3.3 1 1 2 3 3 3 0 Autophagy protein Apg6 Lectin_N PF03954.9 EGO23479.1 - 0.58 9.5 8.2 2.9 7.2 1.0 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.3 EGO23479.1 - 0.65 7.2 32.0 3.3 4.9 22.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1192 PF06698.6 EGO23479.1 - 0.82 9.5 18.9 4.1 7.2 0.5 5.7 4 2 1 6 6 6 0 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.4 EGO23479.1 - 1.1 9.1 33.7 14 5.5 13.6 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AKNA PF12443.3 EGO23479.1 - 1.4 9.0 12.2 0.83 9.6 0.1 3.1 3 0 0 3 3 3 0 AT-hook-containing transcription factor Snapin_Pallidin PF14712.1 EGO23479.1 - 1.6 9.1 22.5 4.9 7.5 4.7 4.2 3 1 0 3 3 3 0 Snapin/Pallidin Prefoldin_2 PF01920.15 EGO23479.1 - 2.2 8.0 30.2 2.1 8.1 1.3 4.4 1 1 2 3 3 3 0 Prefoldin subunit Spc7 PF08317.6 EGO23479.1 - 2.5 6.6 35.4 9.5 4.7 16.9 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Uds1 PF15456.1 EGO23479.1 - 2.8 7.9 24.5 3.8 7.5 1.2 3.8 1 1 1 3 3 3 0 Up-regulated During Septation Tropomyosin_1 PF12718.2 EGO23479.1 - 3.6 7.4 36.1 7.5 6.3 2.4 3.8 1 1 1 3 3 3 0 Tropomyosin like Prefoldin PF02996.12 EGO23479.1 - 4.7 6.8 23.0 3.3 7.3 0.7 4.8 3 2 1 4 4 4 0 Prefoldin subunit SlyX PF04102.7 EGO23479.1 - 5.2 7.5 24.9 8.9 6.7 0.2 5.1 3 2 2 5 5 5 0 SlyX DivIC PF04977.10 EGO23479.1 - 5.2 6.6 34.6 0.22 11.0 1.6 5.2 2 1 1 4 4 4 0 Septum formation initiator ATG16 PF08614.6 EGO23479.1 - 5.5 6.7 36.3 9.8 5.9 7.8 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EGO23479.1 - 6.3 6.6 31.9 2.7 7.8 0.4 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 EGO23479.1 - 8.6 6.2 22.8 9.7 6.0 0.9 5.0 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 EGO23479.1 - 9.4 6.1 35.7 0.23 11.2 3.6 4.9 2 2 3 5 5 5 0 TATA element modulatory factor 1 DNA binding ECH PF00378.15 EGO23480.1 - 1.2e-71 240.7 0.2 1.3e-71 240.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SET PF00856.23 EGO23481.1 - 6.2e-11 42.8 0.0 9.2e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EGO23481.1 - 7.6e-09 35.2 13.1 1.8e-08 34.1 9.1 1.6 1 0 0 1 1 1 1 MYND finger DUF4436 PF14494.1 EGO23482.1 - 1.2e-05 24.8 0.1 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DIOX_N PF14226.1 EGO23483.1 - 4.6e-30 104.5 0.0 8.7e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO23483.1 - 5.1e-18 65.1 0.0 8.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_18 PF12847.2 EGO23484.1 - 7.7e-11 42.5 0.4 9.4e-10 39.0 0.0 2.7 3 1 0 3 3 2 1 Methyltransferase domain PrmA PF06325.8 EGO23484.1 - 2e-10 40.2 0.1 3.4e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EGO23484.1 - 1.4e-09 37.7 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23484.1 - 4.5e-09 36.6 0.0 1.2e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23484.1 - 1.7e-07 31.2 0.0 4.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23484.1 - 1e-06 28.5 0.0 3.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGO23484.1 - 1.8e-06 27.4 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO23484.1 - 0.00012 22.5 1.3 0.00028 21.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23484.1 - 0.0002 21.6 0.0 0.00048 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGO23484.1 - 0.00025 20.7 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.9 EGO23484.1 - 0.0088 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 EGO23484.1 - 0.019 14.9 0.1 0.093 12.7 0.1 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGO23484.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EGO23484.1 - 0.028 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EGO23484.1 - 0.052 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.11 EGO23484.1 - 0.092 11.6 0.0 0.19 10.6 0.0 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF814 PF05670.8 EGO23485.1 - 8e-22 76.9 0.0 1.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) RsgI_N PF12791.2 EGO23485.1 - 0.037 13.6 1.0 0.12 12.1 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma factor N-terminus AUX_IAA PF02309.11 EGO23485.1 - 0.14 11.8 2.8 0.19 11.4 2.0 1.1 1 0 0 1 1 1 0 AUX/IAA family RRM_1 PF00076.17 EGO23486.1 - 2.2e-08 33.6 0.0 7.1e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EGO23486.1 - 2.2e-05 24.4 0.1 6.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_6 PF14259.1 EGO23486.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF494 PF04361.8 EGO23486.1 - 0.018 14.6 1.2 0.092 12.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF494) Trehalase PF01204.13 EGO23487.1 - 5.2e-107 358.5 0.3 7.6e-97 325.0 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EGO23487.1 - 0.0061 15.3 0.2 0.014 14.0 0.1 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Transposase_21 PF02992.9 EGO23488.1 - 4.8e-08 32.3 0.0 1.1e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EGO23488.1 - 1.5e-05 24.4 0.1 3.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) WD40 PF00400.27 EGO23491.1 - 7.3e-17 60.5 11.0 1.2e-08 34.5 0.0 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF972 PF06156.8 EGO23493.1 - 0.0025 18.1 7.7 0.33 11.3 0.4 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 EGO23493.1 - 0.021 14.6 10.5 0.024 14.4 2.1 2.4 2 0 0 2 2 2 0 Tropomyosin like Vfa1 PF08432.5 EGO23493.1 - 0.036 14.0 1.6 0.053 13.5 0.2 1.8 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Reovirus_cap PF00979.12 EGO23493.1 - 0.058 12.3 0.8 0.74 8.6 0.1 2.1 2 0 0 2 2 2 0 Reovirus outer capsid protein, Sigma 3 DUF1664 PF07889.7 EGO23493.1 - 0.061 13.1 7.3 0.38 10.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4472 PF14739.1 EGO23493.1 - 0.063 13.7 11.6 1.3 9.5 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) CALCOCO1 PF07888.6 EGO23493.1 - 0.065 11.5 12.9 0.099 10.9 8.9 1.3 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DELLA PF12041.3 EGO23493.1 - 0.077 12.6 1.2 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal IncA PF04156.9 EGO23493.1 - 0.084 12.4 18.9 0.04 13.5 4.3 2.3 1 1 1 2 2 2 0 IncA protein WEMBL PF05701.6 EGO23493.1 - 0.12 10.8 14.0 0.4 9.0 1.3 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Spectrin PF00435.16 EGO23493.1 - 0.17 12.2 8.5 1.2 9.4 1.4 2.8 1 1 1 2 2 2 0 Spectrin repeat DUF948 PF06103.6 EGO23493.1 - 0.27 11.1 2.7 9.3 6.1 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 EGO23493.1 - 0.28 11.0 16.8 1.3 8.8 2.3 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 EGO23493.1 - 0.28 10.6 11.7 1.3 8.5 1.2 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EGO23493.1 - 0.32 10.7 6.6 1 9.1 2.1 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gal4_dimer PF03902.8 EGO23493.1 - 0.44 10.5 4.4 0.21 11.5 0.7 2.3 3 0 0 3 3 2 0 Gal4-like dimerisation domain Snapin_Pallidin PF14712.1 EGO23493.1 - 0.77 10.1 10.0 1.7 9.0 0.6 3.5 3 1 1 4 4 4 0 Snapin/Pallidin Reo_sigmaC PF04582.7 EGO23493.1 - 0.92 8.6 6.9 0.97 8.5 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EGO23493.1 - 2.4 8.2 14.1 0.83 9.7 1.2 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GrpE PF01025.14 EGO23493.1 - 2.9 7.4 7.3 4.7 6.7 0.6 2.6 1 1 1 2 2 2 0 GrpE Cep57_CLD_2 PF14197.1 EGO23493.1 - 3 7.8 12.4 47 4.0 2.5 3.8 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF4404 PF14357.1 EGO23495.1 - 0.01 16.2 2.1 0.011 16.1 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Pox_A_type_inc PF04508.7 EGO23495.1 - 0.079 12.7 0.4 0.079 12.7 0.3 2.9 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat RapA_C PF12137.3 EGO23495.1 - 0.23 10.2 4.0 0.24 10.1 2.8 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF3277 PF11681.3 EGO23496.1 - 0.062 12.7 0.0 0.067 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Fungal_trans PF04082.13 EGO23497.1 - 0.00045 19.1 0.1 0.0011 17.8 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EGO23499.1 - 0.28 11.5 5.8 0.11 12.8 1.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1014 PF06244.7 EGO23501.1 - 0.066 13.4 0.3 0.074 13.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) STE3 PF02076.10 EGO23503.1 - 2.4e-72 243.4 20.9 2.8e-72 243.1 14.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor RPAP1_C PF08620.5 EGO23504.1 - 1.2e-18 66.6 0.0 2.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EGO23504.1 - 2.7e-08 33.2 2.1 6.7e-08 31.9 1.5 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal COesterase PF00135.23 EGO23505.1 - 7.4e-110 368.1 0.0 1e-109 367.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO23505.1 - 8.9e-05 22.1 0.0 0.00021 20.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO23505.1 - 0.001 18.3 0.7 0.0037 16.5 0.5 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family AAA PF00004.24 EGO23506.1 - 1.4e-39 135.3 0.0 2.9e-39 134.2 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO23506.1 - 7.7e-07 28.3 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO23506.1 - 1.8e-06 28.0 0.1 0.00012 22.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGO23506.1 - 4.2e-06 26.5 0.1 9e-05 22.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO23506.1 - 5e-06 26.6 0.1 0.00039 20.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO23506.1 - 1.1e-05 26.2 0.0 2.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO23506.1 - 1.2e-05 25.1 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO23506.1 - 6.1e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGO23506.1 - 0.00019 21.3 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EGO23506.1 - 0.00021 20.4 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EGO23506.1 - 0.0003 20.0 0.1 0.0017 17.5 0.1 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGO23506.1 - 0.00071 19.0 0.2 0.082 12.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO23506.1 - 0.00084 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EGO23506.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EGO23506.1 - 0.0013 18.9 0.0 0.0035 17.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.1 EGO23506.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO23506.1 - 0.0016 18.7 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EGO23506.1 - 0.0022 17.7 0.0 0.0097 15.5 0.0 1.9 1 1 1 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 EGO23506.1 - 0.0044 16.5 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EGO23506.1 - 0.0054 15.4 0.1 0.011 14.3 0.0 1.4 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EGO23506.1 - 0.0058 15.4 0.1 0.011 14.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 EGO23506.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO23506.1 - 0.0067 15.8 0.1 3.5 6.9 0.0 2.5 3 0 0 3 3 2 1 AAA-like domain Bac_DnaA PF00308.13 EGO23506.1 - 0.0076 15.9 0.0 0.023 14.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial dnaA protein Sigma54_activat PF00158.21 EGO23506.1 - 0.0077 15.7 0.0 0.027 13.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain UPF0079 PF02367.12 EGO23506.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EGO23506.1 - 0.028 14.3 0.1 2.4 8.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO23506.1 - 0.034 13.8 0.0 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 EGO23506.1 - 0.041 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EGO23506.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EGO23506.1 - 0.055 12.5 0.0 0.82 8.7 0.0 2.2 1 1 1 2 2 2 0 KaiC ABC_tran PF00005.22 EGO23506.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SKI PF01202.17 EGO23506.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.6 EGO23506.1 - 0.084 12.4 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_lig_kinase PF08303.6 EGO23506.1 - 0.099 12.5 0.0 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain NB-ARC PF00931.17 EGO23506.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Metal_resist PF13801.1 EGO23507.1 - 0.043 13.7 1.4 0.11 12.5 1.0 1.6 1 1 0 1 1 1 0 Heavy-metal resistance Lamp PF01299.12 EGO23507.1 - 0.11 11.5 0.3 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Herpes_gE PF02480.11 EGO23507.1 - 0.12 10.6 0.1 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PepSY_TM_2 PF13703.1 EGO23507.1 - 0.17 12.0 1.5 0.39 10.9 1.0 1.7 1 1 0 1 1 1 0 PepSY-associated TM helix Sensor PF13796.1 EGO23507.1 - 1.3 8.6 5.1 2 7.9 3.6 1.3 1 0 0 1 1 1 0 Putative sensor Glycos_transf_1 PF00534.15 EGO23508.1 - 1.3e-21 76.8 0.0 1.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO23508.1 - 3.1e-09 37.0 0.0 1.3e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGO23508.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 STE3 PF02076.10 EGO23509.1 - 7e-69 232.0 20.2 8.5e-69 231.7 14.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor Ycf9 PF01737.12 EGO23509.1 - 4.2 6.8 9.3 6.3 6.3 0.7 3.3 3 0 0 3 3 3 0 YCF9 RPAP1_N PF08621.5 EGO23511.1 - 1.5e-06 27.7 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF2246 PF10229.4 EGO23511.1 - 0.043 13.1 0.1 0.046 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) SipA PF09052.5 EGO23511.1 - 0.087 11.2 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Salmonella invasion protein A PUA PF01472.15 EGO23511.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 PUA domain zf-CCHC PF00098.18 EGO23512.1 - 8.7e-07 28.5 2.3 1.4e-06 27.9 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO23512.1 - 0.14 11.8 0.6 0.25 11.0 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO23512.1 - 0.22 11.2 2.9 0.4 10.4 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO23516.1 - 5.8e-07 29.4 3.3 1e-06 28.7 2.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO23516.1 - 0.034 14.0 1.4 0.057 13.3 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2509 PF10713.4 EGO23516.1 - 0.13 12.0 0.3 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) UBN2_3 PF14244.1 EGO23517.1 - 0.078 12.5 0.1 2.9 7.4 0.0 2.1 1 1 0 2 2 2 0 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 EGO23518.1 - 5.8e-11 41.8 0.0 9.3e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_4 PF14392.1 EGO23519.1 - 0.028 14.0 2.0 0.049 13.3 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO23519.1 - 1.5 8.5 4.1 1 9.0 0.3 2.6 3 0 0 3 3 3 0 Zinc knuckle CD24 PF14984.1 EGO23519.1 - 1.6 8.5 8.6 4.3 7.2 6.0 1.7 1 0 0 1 1 1 0 CD24 protein DUF4219 PF13961.1 EGO23520.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) STE3 PF02076.10 EGO23522.1 - 3.9e-37 127.8 10.2 4.4e-37 127.7 7.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor RPAP1_N PF08621.5 EGO23523.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal STE3 PF02076.10 EGO23524.1 - 0.00039 19.5 0.5 0.00066 18.8 0.3 1.3 1 0 0 1 1 1 1 Pheromone A receptor zf-RING_2 PF13639.1 EGO23525.1 - 6.3 6.7 6.9 1.1e+02 2.6 4.8 2.3 1 1 0 1 1 1 0 Ring finger domain Lipase_chap PF03280.9 EGO23526.1 - 0.049 13.1 0.6 0.059 12.8 0.4 1.1 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein U1snRNP70_N PF12220.3 EGO23526.1 - 0.09 13.1 1.1 0.12 12.7 0.8 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal STE3 PF02076.10 EGO23528.1 - 5.2e-74 248.8 16.8 6.1e-74 248.6 11.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor PsbM PF05151.7 EGO23528.1 - 0.86 9.2 4.5 3.4 7.3 3.2 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Baculo_11_kDa PF06143.6 EGO23528.1 - 4.7 6.6 5.7 0.98 8.8 1.1 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family Sad1_UNC PF07738.8 EGO23530.1 - 2.3e-29 101.8 0.1 3.8e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ATP-synt_C PF00137.16 EGO23531.1 - 7.6e-31 105.8 29.8 1.5e-18 66.4 7.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 EGO23531.1 - 4.3 6.9 8.4 2.1 7.9 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF2254 PF10011.4 EGO23534.1 - 0.0033 15.9 0.0 0.0036 15.8 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF4096 PF13340.1 EGO23534.1 - 0.11 12.3 1.4 0.17 11.7 0.5 1.6 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) TctB PF07331.6 EGO23535.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family EGF_CA PF07645.10 EGO23536.1 - 0.036 14.0 3.8 0.05 13.6 2.6 1.2 1 0 0 1 1 1 0 Calcium-binding EGF domain SPC12 PF06645.8 EGO23538.1 - 0.018 14.8 0.4 0.024 14.4 0.3 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Tetraspannin PF00335.15 EGO23539.1 - 3.7e-16 59.0 6.5 5e-16 58.6 4.5 1.1 1 0 0 1 1 1 1 Tetraspanin family ABC2_membrane_4 PF12730.2 EGO23539.1 - 0.39 9.8 10.3 0.2 10.7 5.1 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Oleosin PF01277.12 EGO23539.1 - 1.5 8.3 8.0 0.82 9.2 3.0 2.1 2 0 0 2 2 2 0 Oleosin adh_short PF00106.20 EGO23540.1 - 4.7e-16 59.1 0.0 6.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO23540.1 - 4.7e-07 29.6 0.1 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO23540.1 - 2.1e-05 24.0 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGO23540.1 - 0.00096 19.2 0.1 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGO23540.1 - 0.0017 18.3 0.4 0.0037 17.2 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding TIR-like PF10137.4 EGO23540.1 - 0.031 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain AAA_17 PF13207.1 EGO23540.1 - 0.15 12.9 0.0 0.22 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 EGO23541.1 - 3.1e-29 102.2 0.0 3.8e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO23541.1 - 4.8e-18 65.3 0.1 2.6e-14 53.3 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO23541.1 - 5.4e-07 29.8 0.1 0.0028 17.7 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO23541.1 - 2.3e-06 26.7 0.5 0.0053 15.7 0.0 3.2 1 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EGO23541.1 - 3.1e-06 26.4 0.1 5.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EGO23541.1 - 7.9e-05 22.6 0.2 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGO23541.1 - 0.00016 20.6 4.9 0.0041 16.0 0.1 3.8 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGO23541.1 - 0.00021 20.2 1.7 0.0019 17.1 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 EGO23541.1 - 0.00042 20.4 0.1 0.37 10.9 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO23541.1 - 0.0012 19.0 0.0 0.1 12.8 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EGO23541.1 - 0.0017 17.4 0.2 0.048 12.6 0.0 2.4 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 EGO23541.1 - 0.0028 16.8 0.0 0.029 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO23541.1 - 0.0064 15.0 1.5 0.039 12.4 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 EGO23541.1 - 0.0067 15.0 0.1 0.045 12.3 0.0 2.2 3 0 0 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.1 EGO23541.1 - 0.0071 15.3 0.0 0.86 8.4 0.0 3.3 2 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.12 EGO23541.1 - 0.034 14.5 0.0 4.1 7.9 0.0 2.8 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EGO23541.1 - 0.058 12.7 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EGO23541.1 - 0.066 12.6 0.3 15 5.0 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGO23541.1 - 0.08 12.6 0.4 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GSH_synth_ATP PF03917.12 EGO23546.1 - 2.1e-71 240.4 0.0 1.4e-52 178.5 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGO23546.1 - 2.1e-31 108.1 0.0 4.1e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase p450 PF00067.17 EGO23547.1 - 7.1e-44 150.0 0.0 1.1e-43 149.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Complex1_51K PF01512.12 EGO23548.1 - 2.4e-32 111.7 0.0 2e-31 108.7 0.0 2.3 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGO23548.1 - 6.6e-18 63.6 1.8 1.9e-17 62.1 1.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region EHN PF06441.7 EGO23548.1 - 1.1e-14 54.3 0.0 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Helicase_C PF00271.26 EGO23548.1 - 7.7e-09 35.3 0.1 1.7e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLBB PF10531.4 EGO23548.1 - 4.6e-06 26.4 0.0 1.6e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 SLBB domain Abhydrolase_6 PF12697.2 EGO23548.1 - 6.2e-05 22.9 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family MEA1 PF06910.6 EGO23550.1 - 0.012 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) Cyclin_N PF00134.18 EGO23551.1 - 2.1e-41 140.4 1.4 2e-40 137.2 0.4 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO23551.1 - 4.5e-21 74.9 0.0 8.8e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3314 PF11771.3 EGO23551.1 - 0.049 13.3 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) APH PF01636.18 EGO23554.1 - 3.3e-07 30.2 0.0 1.8e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO23554.1 - 2.1e-05 24.1 0.1 3.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Aldedh PF00171.17 EGO23554.1 - 0.045 12.0 0.0 0.071 11.4 0.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Cyclin_N PF00134.18 EGO23557.1 - 2.8e-36 123.8 0.3 4.9e-36 123.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-C2HC_2 PF13913.1 EGO23558.1 - 0.036 13.7 0.5 0.082 12.5 0.4 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Nairovirus_M PF07948.6 EGO23558.1 - 0.33 9.0 0.1 0.48 8.4 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like gag-asp_proteas PF13975.1 EGO23559.1 - 5.5e-06 26.1 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO23559.1 - 9.7e-05 22.7 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Rogdi_lz PF10259.4 EGO23559.1 - 0.0059 15.7 0.0 0.0074 15.4 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein RVP_2 PF08284.6 EGO23559.1 - 0.0085 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 EGO23560.1 - 1.4e-08 34.2 4.7 2.7e-08 33.3 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO23560.1 - 0.016 14.8 2.0 0.043 13.5 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO23560.1 - 0.026 14.5 0.0 0.026 14.5 0.0 2.0 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO23561.1 - 9.4e-07 28.4 1.5 9.7e-07 28.4 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO23561.1 - 1.8e-05 24.4 5.5 2.5e-05 23.9 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO23561.1 - 0.11 12.0 4.1 0.15 11.6 2.8 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4606 PF15379.1 EGO23561.1 - 0.6 10.1 3.9 0.97 9.5 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) zf-C2HC_2 PF13913.1 EGO23562.1 - 0.014 15.0 0.5 0.03 13.9 0.4 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 EGO23562.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 zinc-finger Nairovirus_M PF07948.6 EGO23562.1 - 0.12 10.4 0.1 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zf-IS66 PF13005.2 EGO23562.1 - 0.24 11.3 0.7 0.45 10.5 0.5 1.4 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 Cyclin_N PF00134.18 EGO23563.1 - 1.2e-22 79.7 0.6 2.6e-21 75.5 0.1 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO23563.1 - 2.7e-21 75.6 0.0 4.7e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3314 PF11771.3 EGO23563.1 - 0.029 14.1 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) Nuc_H_symport PF03825.11 EGO23563.1 - 0.14 10.9 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter DUF3891 PF13030.1 EGO23566.1 - 0.093 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) MCPsignal PF00015.16 EGO23568.1 - 0.014 14.9 0.7 0.023 14.2 0.5 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 EGO23568.1 - 0.015 15.4 0.8 0.067 13.3 0.4 1.9 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PTRF_SDPR PF15237.1 EGO23568.1 - 0.025 14.0 0.3 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 PTRF/SDPR family Seryl_tRNA_N PF02403.17 EGO23568.1 - 0.027 14.4 0.3 0.045 13.7 0.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CHASE3 PF05227.8 EGO23568.1 - 0.031 13.9 0.8 0.077 12.6 0.6 1.6 1 1 0 1 1 1 0 CHASE3 domain DUF479 PF04336.7 EGO23568.1 - 0.035 14.2 0.1 0.077 13.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF479 FlgN PF05130.7 EGO23568.1 - 0.054 13.7 1.0 0.075 13.2 0.7 1.2 1 0 0 1 1 1 0 FlgN protein NPV_P10 PF05531.7 EGO23568.1 - 0.058 13.6 1.3 0.23 11.7 0.3 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MutS_III PF05192.13 EGO23568.1 - 0.065 13.0 0.4 0.095 12.4 0.3 1.3 1 0 0 1 1 1 0 MutS domain III Transcrip_act PF04949.8 EGO23568.1 - 0.068 12.7 0.1 1.7 8.2 0.1 2.0 1 1 0 1 1 1 0 Transcriptional activator Syntaxin PF00804.20 EGO23568.1 - 0.14 12.3 0.9 0.34 11.0 0.5 1.6 1 1 0 1 1 1 0 Syntaxin MbeD_MobD PF04899.7 EGO23568.1 - 0.14 12.0 0.8 2 8.3 0.2 2.2 2 0 0 2 2 2 0 MbeD/MobD like Spc7 PF08317.6 EGO23568.1 - 0.16 10.6 1.2 0.21 10.1 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGO23568.1 - 0.49 9.9 5.4 0.7 9.4 3.7 1.4 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EGO23568.1 - 0.73 9.3 3.1 2 7.9 0.5 2.5 1 1 2 3 3 3 0 Septum formation initiator DUF2205 PF10224.4 EGO23568.1 - 1.1 8.8 4.5 0.46 10.0 0.8 2.1 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) POP1 PF06978.6 EGO23569.1 - 1.7e-47 161.5 19.2 3.1e-28 98.7 0.9 3.0 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGO23569.1 - 1.1e-27 95.6 0.8 1.1e-27 95.6 0.5 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.16 EGO23569.1 - 0.0006 19.2 0.0 0.038 13.3 0.0 2.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain Receptor_2B4 PF11465.3 EGO23569.1 - 0.027 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 GCV_T_C PF08669.6 EGO23569.1 - 0.036 14.0 0.3 0.093 12.7 0.0 1.8 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain Nbl1_Borealin_N PF10444.4 EGO23570.1 - 1.3e-08 34.0 0.0 3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal MogR_DNAbind PF12181.3 EGO23570.1 - 0.0032 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 DNA binding domain of the motility gene repressor (MogR) 3Beta_HSD PF01073.14 EGO23571.1 - 9.9e-64 214.7 0.0 4.5e-58 196.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO23571.1 - 6.6e-32 110.8 0.1 9.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO23571.1 - 1.8e-15 57.4 0.0 2.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO23571.1 - 5.8e-15 54.9 0.0 8.2e-12 44.5 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGO23571.1 - 6.5e-14 51.4 0.1 9.4e-14 50.9 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO23571.1 - 0.00036 19.5 1.9 0.0036 16.2 1.3 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EGO23571.1 - 0.0073 15.9 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EGO23571.1 - 0.012 15.6 0.2 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EGO23571.1 - 0.012 15.5 0.3 0.093 12.6 0.2 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 EGO23571.1 - 0.088 12.0 0.3 0.27 10.4 0.2 1.8 1 1 0 1 1 1 0 NmrA-like family DUF1049 PF06305.6 EGO23572.1 - 1.8 8.1 5.4 29 4.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) 3Beta_HSD PF01073.14 EGO23573.1 - 6.2e-26 90.7 0.0 1.1e-25 89.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGO23573.1 - 3.7e-19 68.6 0.1 3.2e-16 59.0 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO23573.1 - 3.9e-14 52.6 0.0 7e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO23573.1 - 6.7e-06 25.2 0.0 1.2e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO23573.1 - 5.5e-05 23.2 0.0 0.00027 20.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO23573.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO23573.1 - 0.0007 18.5 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EGO23573.1 - 0.0049 16.5 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Elong_Iki1 PF10483.4 EGO23575.1 - 4.2e-06 26.3 0.6 0.00086 18.7 0.0 2.5 2 1 0 2 2 2 2 Elongator subunit Iki1 Serglycin PF04360.7 EGO23575.1 - 0.19 11.4 0.6 0.32 10.7 0.4 1.3 1 0 0 1 1 1 0 Serglycin Usp PF00582.21 EGO23576.1 - 1.4e-20 73.9 1.6 1.9e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.1 EGO23576.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4456 PF14644.1 EGO23578.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Resolvase PF00239.16 EGO23578.1 - 0.02 14.7 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain NACHT PF05729.7 EGO23578.1 - 0.095 12.3 0.4 0.17 11.5 0.2 1.5 1 1 0 1 1 1 0 NACHT domain MitMem_reg PF13012.1 EGO23578.1 - 0.1 12.7 0.2 5.6 7.0 0.0 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function RPAP3_C PF13877.1 EGO23579.1 - 6.5e-08 32.4 0.0 7.2e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Peptidase_M20 PF01546.23 EGO23581.1 - 3e-27 95.3 0.0 4.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EGO23581.1 - 5e-15 54.7 18.8 0.0012 18.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.9 EGO23581.1 - 1.8e-12 47.0 0.0 3.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.1 EGO23581.1 - 0.014 15.6 0.0 10 6.5 0.0 3.2 2 0 0 2 2 2 0 PQQ-like domain Neisseria_PilC PF05567.6 EGO23581.1 - 0.23 10.4 0.0 0.53 9.2 0.0 1.5 2 0 0 2 2 2 0 Neisseria PilC beta-propeller domain DUF2220 PF09983.4 EGO23582.1 - 0.11 11.6 0.6 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) DAHP_synth_1 PF00793.15 EGO23583.1 - 9.5e-93 309.7 0.0 1.2e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.10 EGO23584.1 - 3.4e-19 67.8 7.2 4.5e-19 67.5 5.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 EGO23584.1 - 0.042 12.8 0.1 0.042 12.8 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 AhpC-TSA PF00578.16 EGO23586.1 - 4.7e-30 103.8 0.0 6.3e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO23586.1 - 2.8e-20 72.3 0.0 3.9e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGO23586.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.1 EGO23586.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Acetyltransf_3 PF13302.1 EGO23587.1 - 3.1e-19 69.5 0.0 3.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO23587.1 - 5.6e-14 52.3 0.0 6.3e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO23587.1 - 7.1e-13 48.4 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO23587.1 - 3e-07 30.5 0.0 4.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO23587.1 - 3.5e-05 23.7 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO23587.1 - 0.00016 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO23587.1 - 0.00052 19.7 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein TRAP_alpha PF03896.11 EGO23589.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1180 PF06679.7 EGO23589.1 - 0.017 15.0 0.4 0.017 15.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 EGO23589.1 - 0.14 10.3 0.0 0.25 9.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pkinase PF00069.20 EGO23591.1 - 1.1e-49 168.9 0.0 1.4e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23591.1 - 9e-27 93.7 0.1 7.3e-26 90.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO23591.1 - 2.2e-05 23.5 0.0 3.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGO23591.1 - 0.00057 19.2 0.2 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGO23591.1 - 0.0017 17.4 0.1 0.0036 16.3 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO23591.1 - 0.15 11.7 0.1 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family NMO PF03060.10 EGO23592.1 - 8.7e-64 215.7 0.1 1.2e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO23592.1 - 1.2e-09 37.5 0.3 6.8e-05 21.9 0.3 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO23592.1 - 0.0032 16.3 0.2 0.0051 15.7 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EGO23592.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 EGO23592.1 - 0.044 12.7 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.12 EGO23592.1 - 0.056 12.5 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI LRR_4 PF12799.2 EGO23593.1 - 0.038 13.6 1.0 21 4.8 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) YL1 PF05764.8 EGO23593.1 - 2.7 7.5 7.0 3.7 7.0 4.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2205 PF10224.4 EGO23594.1 - 6.2e-12 44.9 0.1 7.4e-12 44.6 0.1 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EGO23594.1 - 0.012 15.9 0.3 0.014 15.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 EGO23594.1 - 0.051 11.3 0.3 0.057 11.1 0.2 1.0 1 0 0 1 1 1 0 Myosin tail DivIC PF04977.10 EGO23594.1 - 0.073 12.5 0.1 0.094 12.2 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator YopE PF03545.8 EGO23594.1 - 0.08 12.8 0.0 0.69 9.8 0.0 2.0 1 1 1 2 2 2 0 Yersinia virulence determinant (YopE) Proteasom_Rpn13 PF04683.8 EGO23595.1 - 7.5e-27 93.2 0.0 1.1e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Arf PF00025.16 EGO23596.1 - 5.1e-35 120.2 0.0 5.8e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGO23596.1 - 1.1e-17 63.8 0.0 1.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO23596.1 - 7.9e-13 48.9 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGO23596.1 - 1.9e-09 36.9 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGO23596.1 - 3.7e-08 32.8 0.0 4.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGO23596.1 - 2.6e-05 23.0 0.3 4.4e-05 22.3 0.1 1.4 1 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EGO23596.1 - 3.3e-05 23.8 0.0 4.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO23596.1 - 0.00023 20.6 0.0 0.00097 18.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO23596.1 - 0.005 16.6 0.6 0.42 10.4 0.6 2.1 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 EGO23596.1 - 0.046 13.2 0.3 5.4 6.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EGO23596.1 - 0.11 12.1 0.0 0.8 9.3 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Pet127 PF08634.5 EGO23597.1 - 1.4e-99 332.7 0.0 3e-99 331.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein Pet127 MFS_1 PF07690.11 EGO23598.1 - 2.6e-15 55.9 34.0 2.6e-15 55.9 23.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO23598.1 - 4e-13 49.1 6.8 4.5e-13 48.9 3.3 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 F-box-like PF12937.2 EGO23599.1 - 0.00093 18.8 2.4 0.0032 17.1 1.7 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EGO23599.1 - 0.0056 16.6 0.0 17 5.8 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 EGO23599.1 - 0.03 13.9 0.4 3.3 7.4 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_S19e PF01090.14 EGO23600.1 - 1.5e-56 189.6 0.0 1.8e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Androgen_recep PF02166.11 EGO23600.1 - 0.11 11.3 0.0 0.26 10.1 0.0 1.5 1 1 1 2 2 2 0 Androgen receptor Acetyltransf_3 PF13302.1 EGO23601.1 - 4e-16 59.4 0.1 6.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO23601.1 - 2.6e-12 46.5 0.0 4.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGO23601.1 - 1e-10 41.7 0.3 1.3e-10 41.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO23601.1 - 0.00054 20.0 0.0 0.00076 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPP_enzyme_N PF02776.13 EGO23602.1 - 1.6e-40 138.3 0.1 2.5e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO23602.1 - 2.5e-24 85.6 0.0 4.7e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGO23602.1 - 1.2e-15 57.4 0.0 3.6e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain STE3 PF02076.10 EGO23603.1 - 3.6e-68 229.7 13.6 4.3e-68 229.4 9.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF3561 PF12084.3 EGO23603.1 - 0.016 15.0 3.1 0.049 13.4 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) STE3 PF02076.10 EGO23605.1 - 4.2e-66 222.9 20.9 5e-66 222.6 14.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor Helicase_C_2 PF13307.1 EGO23606.1 - 1.7e-18 67.1 0.4 1.8e-18 67.0 0.3 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Trypsin_2 PF13365.1 EGO23607.1 - 0.00071 19.5 0.0 0.0025 17.7 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 EGO23607.1 - 0.048 12.6 1.0 0.24 10.3 0.4 1.9 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Helicase_C_2 PF13307.1 EGO23609.1 - 1.1e-52 178.3 0.0 2.4e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EGO23609.1 - 1.5e-41 141.7 0.0 3.5e-41 140.5 0.0 1.7 1 1 0 1 1 1 1 DEAD_2 PDGLE PF13190.1 EGO23609.1 - 0.0002 20.9 0.1 0.13 11.9 0.0 3.0 3 0 0 3 3 3 2 PDGLE domain PhoH PF02562.11 EGO23609.1 - 0.00093 18.4 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein DEAD PF00270.24 EGO23609.1 - 0.016 14.7 1.3 0.3 10.5 0.6 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO23609.1 - 0.026 14.6 0.0 9.4 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EGO23609.1 - 0.028 14.2 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DivIC PF04977.10 EGO23609.1 - 4.8 6.7 7.2 10 5.6 4.1 2.2 2 0 0 2 2 2 0 Septum formation initiator ATP-synt_B PF00430.13 EGO23609.1 - 5.2 6.8 9.4 11 5.8 6.5 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AAA_30 PF13604.1 EGO23609.1 - 8.9 5.8 8.3 2 7.9 0.0 2.7 2 1 1 3 3 3 0 AAA domain Hpt PF01627.18 EGO23610.1 - 5.1e-10 39.2 0.0 7.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain CoA_transf_3 PF02515.12 EGO23611.1 - 1.1e-66 223.7 0.0 1.5e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Syntaxin_2 PF14523.1 EGO23612.1 - 0.58 10.2 6.6 0.27 11.2 0.3 3.1 4 0 0 4 4 4 0 Syntaxin-like protein Na_Ca_ex PF01699.19 EGO23613.1 - 2.1e-24 85.7 32.7 1e-13 51.1 6.3 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGO23613.1 - 1.8e-11 44.2 9.3 1.8e-11 44.2 6.4 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF307) CPSF_A PF03178.10 EGO23614.1 - 2.9e-49 167.8 0.2 1.5e-48 165.5 0.1 2.3 3 1 1 4 4 4 1 CPSF A subunit region MMS1_N PF10433.4 EGO23614.1 - 1.6e-42 145.3 0.0 2.7e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CBFD_NFYB_HMF PF00808.18 EGO23615.1 - 1.8e-15 56.7 0.9 3e-15 56.0 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO23615.1 - 6.4e-08 32.6 0.4 9.7e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGO23615.1 - 0.011 15.4 0.1 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DUF3654 PF12376.3 EGO23615.1 - 0.043 13.6 0.3 0.062 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) Ribosomal_L1 PF00687.16 EGO23615.1 - 0.22 10.8 1.3 0.31 10.3 0.9 1.1 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family TAF4 PF05236.9 EGO23615.1 - 2.9 7.0 6.6 34 3.5 4.7 2.0 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family HIT PF01230.18 EGO23616.1 - 1.3e-21 76.9 0.2 2e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO23616.1 - 5.4e-14 52.4 0.1 7.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGO23616.1 - 2.6e-05 23.8 0.1 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 She9_MDM33 PF05546.6 EGO23617.1 - 1.7e-71 240.0 9.6 1.7e-71 240.0 6.6 1.4 2 0 0 2 2 2 1 She9 / Mdm33 family MbeB_N PF04837.7 EGO23617.1 - 0.05 13.6 4.7 3.7 7.7 0.2 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Tmemb_9 PF05434.6 EGO23617.1 - 1.6 8.4 3.7 0.99 9.1 0.0 2.2 2 1 1 3 3 3 0 TMEM9 DivIC PF04977.10 EGO23617.1 - 5.5 6.5 11.4 2.4 7.7 1.1 3.7 3 1 0 4 4 4 0 Septum formation initiator FAD_binding_1 PF00667.15 EGO23618.1 - 5.1e-56 189.5 0.0 3.3e-55 186.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGO23618.1 - 1.7e-28 99.4 0.4 3.2e-28 98.5 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGO23618.1 - 8e-21 74.6 0.0 4e-20 72.3 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGO23618.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain Yae1_N PF09811.4 EGO23620.1 - 3.1e-13 49.0 0.3 4.9e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal UAA PF08449.6 EGO23621.1 - 3.7e-67 226.4 8.9 3.2e-63 213.4 4.1 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EGO23621.1 - 6.1e-09 35.9 22.4 7.5e-07 29.2 6.8 4.2 3 2 0 4 4 4 2 EamA-like transporter family TPT PF03151.11 EGO23621.1 - 0.00047 19.8 6.0 0.00047 19.8 4.2 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EGO23621.1 - 0.00088 18.4 3.0 0.43 9.6 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EGO23621.1 - 0.0012 19.0 4.8 0.0012 19.0 3.3 3.9 3 2 1 4 4 4 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 EGO23621.1 - 0.11 12.3 3.4 0.91 9.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 cobW PF02492.14 EGO23622.1 - 1.6e-43 148.2 0.9 1.6e-43 148.1 0.1 1.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGO23622.1 - 5.7e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 EGO23622.1 - 4.6e-06 26.1 0.0 0.0056 16.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGO23622.1 - 0.0012 17.7 0.3 0.091 11.5 0.0 3.3 4 0 0 4 4 4 1 ArgK protein AAA_33 PF13671.1 EGO23622.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO23622.1 - 0.0048 17.0 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGO23622.1 - 0.005 16.7 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EGO23622.1 - 0.0052 16.4 0.0 0.043 13.5 0.0 2.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGO23622.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Arf PF00025.16 EGO23622.1 - 0.0081 15.4 0.2 1.1 8.4 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Arch_ATPase PF01637.13 EGO23622.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 EGO23622.1 - 0.01 16.1 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGO23622.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EGO23622.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 EGO23622.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EGO23622.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 EGO23622.1 - 0.12 12.8 0.0 0.54 10.7 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EGO23623.1 - 4.1e-53 179.6 0.0 7.2e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGO23623.1 - 3e-15 55.8 0.0 7.1e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGO23623.1 - 7.6e-09 35.3 0.0 1.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGO23623.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EGO23623.1 - 0.00072 19.6 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EGO23623.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein EFG_IV PF03764.13 EGO23623.1 - 0.011 15.2 0.0 1.1 8.7 0.0 3.2 2 1 0 2 2 2 0 Elongation factor G, domain IV RasGEF PF00617.14 EGO23624.1 - 2.3e-61 206.8 0.3 5.1e-61 205.6 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO23624.1 - 5.1e-22 77.9 0.2 1.2e-21 76.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Pkinase PF00069.20 EGO23625.1 - 1.5e-65 220.9 0.0 3.1e-65 219.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23625.1 - 4.5e-37 127.5 0.0 7.2e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EGO23625.1 - 5e-23 80.6 21.8 6.4e-16 57.8 4.8 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EGO23625.1 - 7.8e-20 70.3 28.7 2.3e-11 43.2 6.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EGO23625.1 - 6.7e-10 39.3 2.2 9.6e-10 38.8 0.2 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 EGO23625.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 C2 domain Kinase-like PF14531.1 EGO23625.1 - 0.037 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.1 EGO23625.1 - 0.066 13.2 17.4 0.32 10.9 1.9 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Endosulfine PF04667.12 EGO23627.1 - 2.1e-20 72.4 0.0 2.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.11 EGO23628.1 - 1.4e-34 119.1 1.2 1.7e-34 118.9 0.8 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_3 PF14582.1 EGO23628.1 - 0.07 12.2 0.0 0.23 10.5 0.0 1.8 3 0 0 3 3 3 0 Metallophosphoesterase, calcineurin superfamily NUDIX PF00293.23 EGO23629.1 - 1.3e-14 53.9 0.1 8.9e-14 51.2 0.0 2.0 1 1 2 3 3 3 1 NUDIX domain CwfJ_C_1 PF04677.10 EGO23630.1 - 1e-30 105.8 0.0 1.5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGO23630.1 - 1.6e-25 89.4 0.1 5.5e-23 81.3 0.0 2.6 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 HpcH_HpaI PF03328.9 EGO23631.1 - 1.1e-41 142.1 0.0 2.3e-41 141.1 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EGO23631.1 - 2.9e-11 42.7 0.1 1.4e-07 30.6 0.0 2.4 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold HA2 PF04408.18 EGO23632.1 - 1.8e-26 92.1 0.0 2.7e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO23632.1 - 4.5e-26 90.9 0.0 7.8e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF427 PF04248.7 EGO23633.1 - 4.2e-32 109.6 1.2 4.7e-32 109.5 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Mito_carr PF00153.22 EGO23634.1 - 2.8e-73 241.6 1.0 5.5e-25 86.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4448 PF14610.1 EGO23635.1 - 0.015 14.7 2.2 0.13 11.7 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3328 PF11807.3 EGO23635.1 - 0.05 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Peptidase_M56 PF05569.6 EGO23635.1 - 0.22 10.4 0.2 0.32 9.9 0.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 HAMP PF00672.20 EGO23635.1 - 0.4 10.8 2.7 0.87 9.8 1.9 1.6 1 0 0 1 1 1 0 HAMP domain AMP-binding PF00501.23 EGO23637.1 - 3.7e-70 236.4 0.0 5e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO23637.1 - 3.6e-14 53.4 0.0 1.1e-13 51.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3132 PF11330.3 EGO23637.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) AMP-binding PF00501.23 EGO23638.1 - 2e-68 230.6 0.0 1.7e-37 128.8 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EGO23638.1 - 7.2e-14 52.4 0.3 1.6e-13 51.3 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_C97 PF05903.9 EGO23639.1 - 1.1e-39 135.6 0.0 2.1e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EGO23639.1 - 5.3e-27 94.2 0.1 7.4e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EGO23639.1 - 5.5e-16 58.1 0.0 1.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGO23639.1 - 2.5e-06 27.6 0.0 2.9e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EGO23639.1 - 0.0077 15.7 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Redoxin XLF PF09302.6 EGO23639.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 XLF (XRCC4-like factor) Carn_acyltransf PF00755.15 EGO23640.1 - 9.5e-163 542.4 0.0 1.2e-162 542.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fungal_trans PF04082.13 EGO23642.1 - 1.9e-11 43.3 1.3 3.8e-11 42.3 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3399 PF11879.3 EGO23642.1 - 0.00083 19.5 0.2 0.0033 17.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Fer4_6 PF12837.2 EGO23642.1 - 1.1 9.1 4.3 2.5 8.1 3.0 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain CAF1 PF04857.15 EGO23643.1 - 9.6e-67 225.0 0.0 1.5e-66 224.4 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease FCH PF00611.18 EGO23646.1 - 2.2e-13 50.2 0.0 5.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Baculo_PEP_C PF04513.7 EGO23646.1 - 4.9 6.9 9.1 11 5.8 1.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DPBB_1 PF03330.13 EGO23648.1 - 2.8e-07 30.4 0.3 7.4e-06 25.8 0.0 2.5 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGO23648.1 - 0.00033 20.3 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Barwin family Ribosomal_L37e PF01907.14 EGO23648.1 - 0.051 13.3 0.6 0.082 12.7 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e GGGtGRT PF14057.1 EGO23648.1 - 0.15 10.8 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 GGGtGRT protein Rsbr_N PF08678.5 EGO23649.1 - 0.037 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Rsbr N terminal Band_7 PF01145.20 EGO23650.1 - 3e-25 89.1 1.1 5.2e-25 88.3 0.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family HrpE PF06188.7 EGO23650.1 - 4.9 6.8 8.0 4.8 6.8 4.8 1.5 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E F-box-like PF12937.2 EGO23651.1 - 0.0027 17.3 0.2 0.0081 15.8 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO23651.1 - 0.012 15.2 3.2 0.028 14.0 0.1 2.9 3 0 0 3 3 3 0 F-box domain Chromate_transp PF02417.10 EGO23653.1 - 0.072 12.6 0.5 0.13 11.8 0.2 1.5 1 1 0 1 1 1 0 Chromate transporter DLH PF01738.13 EGO23654.1 - 2.8e-17 62.7 0.0 9e-17 61.0 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO23654.1 - 8.2e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO23654.1 - 0.0018 17.8 0.0 0.012 15.1 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO23654.1 - 0.0085 16.0 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_permease_2 PF13520.1 EGO23655.1 - 1e-24 86.8 30.2 4.8e-17 61.6 8.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 EGO23655.1 - 8.6e-09 34.2 20.5 3.9e-07 28.7 5.8 2.6 1 1 0 2 2 2 2 Amino acid permease DDE_1 PF03184.14 EGO23656.1 - 8.3e-22 77.4 0.0 3e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Trehalase_Ca-bi PF07492.6 EGO23656.1 - 0.015 14.5 1.7 0.032 13.5 1.2 1.4 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain SAP PF02037.22 EGO23656.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.9 2 0 0 2 2 2 0 SAP domain Reo_sigmaC PF04582.7 EGO23657.1 - 0.013 14.6 3.5 0.019 14.1 2.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EGO23657.1 - 0.023 14.5 10.1 0.11 12.4 7.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EGO23657.1 - 1.1 9.2 14.8 0.061 13.2 6.4 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GvpK PF05121.7 EGO23657.1 - 1.9 8.3 6.8 0.49 10.2 0.5 2.6 2 1 0 2 2 2 0 Gas vesicle protein K Nnf1 PF03980.9 EGO23657.1 - 2.4 8.2 15.9 0.47 10.4 1.1 2.9 2 1 1 3 3 3 0 Nnf1 DUF506 PF04720.7 EGO23657.1 - 3.1 7.3 8.3 0.085 12.4 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF506) DivIC PF04977.10 EGO23657.1 - 3.9 7.0 8.4 0.73 9.3 0.5 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.7 EGO23657.1 - 4.3 7.1 8.6 1.6 8.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EGO23657.1 - 8.7 5.2 14.2 0.27 10.2 5.5 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 RPA_interact_N PF14766.1 EGO23659.1 - 0.82 9.1 3.1 0.69 9.4 0.7 2.0 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Amidohydro_5 PF13594.1 EGO23661.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGO23661.1 - 0.014 15.4 3.4 0.039 13.9 2.3 2.1 1 1 0 1 1 1 0 Amidohydrolase Pkinase PF00069.20 EGO23662.1 - 2.6e-20 72.6 0.0 4.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23662.1 - 4.5e-06 25.9 0.0 1.5e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S19e PF01090.14 EGO23662.1 - 0.013 14.9 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S19e FA_desaturase PF00487.19 EGO23663.1 - 2.3e-23 82.9 19.6 5e-23 81.8 13.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGO23663.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) D123 PF07065.9 EGO23664.1 - 4.2e-05 22.7 0.0 4.7e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 D123 DUF972 PF06156.8 EGO23665.1 - 0.0015 18.8 6.3 0.52 10.6 0.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF972) DUF1664 PF07889.7 EGO23665.1 - 0.034 13.9 5.3 0.36 10.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2800 PF10926.3 EGO23665.1 - 0.051 12.6 1.6 3.3 6.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2800) Reovirus_cap PF00979.12 EGO23665.1 - 0.054 12.4 0.4 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Reovirus outer capsid protein, Sigma 3 TSC22 PF01166.13 EGO23665.1 - 0.077 12.9 1.6 1.2 9.1 0.1 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4472 PF14739.1 EGO23665.1 - 0.094 13.1 10.6 1.8 9.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF1866 PF08952.6 EGO23665.1 - 0.098 12.1 0.8 0.23 11.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) CALCOCO1 PF07888.6 EGO23665.1 - 0.11 10.7 11.0 0.16 10.2 7.6 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Gal4_dimer PF03902.8 EGO23665.1 - 0.13 12.2 4.0 0.11 12.4 0.6 2.6 3 0 0 3 3 2 0 Gal4-like dimerisation domain IncA PF04156.9 EGO23665.1 - 0.14 11.7 19.2 0.043 13.4 3.0 2.7 2 1 1 3 3 3 0 IncA protein Tropomyosin_1 PF12718.2 EGO23665.1 - 0.19 11.5 12.6 0.036 13.9 2.4 2.4 1 1 1 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EGO23665.1 - 0.29 10.9 15.3 1.2 8.9 1.4 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EGO23665.1 - 0.32 10.8 2.2 14 5.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EGO23665.1 - 0.36 10.9 11.5 0.58 10.2 0.4 2.9 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 EGO23665.1 - 0.43 10.1 10.9 2.5 7.6 1.5 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EGO23665.1 - 0.49 10.2 6.9 0.55 10.0 0.8 3.1 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 EGO23665.1 - 0.5 8.7 12.1 1.6 7.1 0.6 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EGO23665.1 - 0.97 8.5 4.2 1.6 7.8 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Transposase_22 PF02994.9 EGO23665.1 - 1.1 7.6 10.0 1.9 6.9 1.5 2.2 1 1 1 2 2 2 0 L1 transposable element Cep57_CLD_2 PF14197.1 EGO23665.1 - 2.9 7.9 10.6 13 5.8 1.1 3.9 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 WD40 PF00400.27 EGO23666.1 - 5.7e-17 60.8 12.9 3.5e-09 36.1 0.1 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Exo_endo_phos PF03372.18 EGO23670.1 - 5.8e-08 32.9 0.2 1.4e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0160 PF03690.8 EGO23671.1 - 4e-126 420.7 0.0 4.5e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Phage_Gp14 PF10666.4 EGO23672.1 - 0.034 14.0 0.2 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Phage protein Gp14 DDE_3 PF13358.1 EGO23674.1 - 1.2e-08 34.7 0.3 2.1e-08 34.0 0.1 1.5 1 1 1 2 2 2 1 DDE superfamily endonuclease Mpv17_PMP22 PF04117.7 EGO23674.1 - 0.057 13.0 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Mpv17 / PMP22 family DUF3684 PF12449.3 EGO23675.1 - 7.5e-22 76.8 0.0 9.5e-22 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Transket_pyr PF02779.19 EGO23676.1 - 8.9e-66 220.7 0.0 1.3e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGO23676.1 - 1.7e-56 191.1 0.0 2.3e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component zf-C2H2 PF00096.21 EGO23679.1 - 0.0092 16.2 0.4 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO23679.1 - 0.13 12.6 0.1 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Nipped-B_C PF12830.2 EGO23681.1 - 2.4e-51 174.0 1.0 1e-50 171.9 0.7 2.2 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EGO23681.1 - 5.2e-12 45.4 0.2 5.2e-12 45.4 0.1 3.8 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EGO23681.1 - 0.0019 18.1 0.3 0.96 9.7 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EGO23681.1 - 0.07 13.6 2.3 9.1 6.9 0.1 4.4 2 1 2 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.1 EGO23681.1 - 4.2 7.7 13.9 0.034 14.4 0.4 4.4 5 1 0 5 5 5 0 HEAT repeats HA2 PF04408.18 EGO23683.1 - 3e-23 81.7 0.1 5.5e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGO23683.1 - 3.5e-13 49.2 0.0 8.3e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGO23683.1 - 8.9e-11 41.6 0.0 2.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGO23683.1 - 6.7e-07 28.9 0.1 1.5e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO23683.1 - 9.3e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO23683.1 - 0.0087 15.7 0.4 0.021 14.5 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EGO23683.1 - 0.0094 15.0 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 KaiC MlrC_C PF07171.7 EGO23683.1 - 0.012 15.1 0.1 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 MlrC C-terminus Arch_ATPase PF01637.13 EGO23683.1 - 0.024 14.3 0.1 9.8 5.7 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_29 PF13555.1 EGO23683.1 - 0.032 13.7 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EGO23683.1 - 0.052 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EGO23683.1 - 0.059 12.6 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein VRP3 PF03536.10 EGO23683.1 - 0.084 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein ResIII PF04851.10 EGO23683.1 - 0.13 12.1 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF663 PF04950.7 EGO23684.1 - 1.5e-11 43.8 0.0 1.6e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF663) CIA30 PF08547.7 EGO23684.1 - 0.094 12.5 0.0 0.096 12.5 0.0 1.0 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DUF663 PF04950.7 EGO23685.1 - 9.2e-08 31.3 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) DUF3015 PF11220.3 EGO23685.1 - 0.00052 19.6 0.3 0.0022 17.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3015) Cep57_MT_bd PF06657.8 EGO23686.1 - 1.4e-24 85.8 0.1 1.4e-24 85.8 0.1 2.9 2 1 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EGO23686.1 - 2.2e-09 37.1 7.4 2.2e-09 37.1 5.1 2.2 2 0 0 2 2 1 1 Centrosome localisation domain of PPC89 Mnd1 PF03962.10 EGO23686.1 - 0.0025 17.5 0.5 0.015 14.9 0.2 2.3 2 0 0 2 2 2 1 Mnd1 family TMF_DNA_bd PF12329.3 EGO23686.1 - 0.0071 16.1 0.7 0.0071 16.1 0.5 3.3 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EGO23686.1 - 0.011 15.4 6.7 0.011 15.4 4.7 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EGO23686.1 - 0.45 9.1 6.0 1.1 7.8 4.2 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.3 EGO23686.1 - 0.81 9.7 7.2 0.23 11.4 2.2 2.1 1 1 0 2 2 2 0 YlqD protein CorA PF01544.13 EGO23686.1 - 0.81 8.6 7.2 0.1 11.5 1.8 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IFT57 PF10498.4 EGO23686.1 - 1 8.0 4.4 0.83 8.3 1.3 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 SLD3 PF08639.5 EGO23686.1 - 1.4 7.5 11.4 2.4 6.6 7.9 1.3 1 0 0 1 1 1 0 DNA replication regulator SLD3 APG6 PF04111.7 EGO23686.1 - 3.6 6.5 5.7 6.3 5.7 3.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 COMP PF11598.3 EGO23686.1 - 3.8 7.6 5.5 23 5.1 1.9 3.0 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein ATG16 PF08614.6 EGO23686.1 - 4.2 7.1 15.0 0.032 14.0 3.0 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HALZ PF02183.13 EGO23686.1 - 4.8 6.9 13.5 4.3 7.1 0.1 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF4200 PF13863.1 EGO23686.1 - 6.6 6.6 10.6 10 6.0 3.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) EHN PF06441.7 EGO23687.1 - 2.3e-30 104.7 0.3 1.8e-29 101.8 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGO23687.1 - 2.3e-11 43.9 1.3 4.3e-11 43.1 0.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO23687.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4190 PF13828.1 EGO23688.1 - 0.039 13.4 0.3 0.09 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Ribosomal_L23eN PF03939.8 EGO23689.1 - 3.1e-19 68.7 8.9 3.1e-19 68.7 6.1 2.6 2 2 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGO23689.1 - 7.3e-19 67.5 1.9 7.3e-19 67.5 1.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 EGO23689.1 - 0.0049 16.6 0.1 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal ADH_N PF08240.7 EGO23690.1 - 1.5e-25 89.0 0.4 2.6e-25 88.3 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO23690.1 - 2.3e-09 36.8 0.0 6.1e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_9 PF13454.1 EGO23690.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NADH_4Fe-4S PF10589.4 EGO23690.1 - 2.6 7.2 6.2 6.7 5.9 4.3 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SMC_N PF02463.14 EGO23691.1 - 7.2e-69 231.3 1.3 9.6e-69 230.9 0.9 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGO23691.1 - 2.9e-30 104.7 0.0 1.8e-29 102.1 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGO23691.1 - 1.1e-14 55.1 1.3 1.4e-06 28.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGO23691.1 - 1.4e-11 45.1 37.4 1.4e-11 45.1 25.9 6.3 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO23691.1 - 0.00092 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGO23691.1 - 0.0067 16.7 18.6 0.086 13.1 0.6 5.4 3 2 1 4 4 4 2 ABC transporter Reo_sigmaC PF04582.7 EGO23691.1 - 0.11 11.5 24.8 1.2 8.2 1.2 5.4 5 1 0 5 5 5 0 Reovirus sigma C capsid protein DUF87 PF01935.12 EGO23691.1 - 0.27 11.0 0.0 0.27 11.0 0.0 5.7 4 2 2 6 6 6 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EGO23691.1 - 0.39 10.1 0.0 0.39 10.1 0.0 4.1 5 0 0 5 5 5 0 FtsK/SpoIIIE family RasGEF PF00617.14 EGO23692.1 - 2.7e-57 193.5 1.1 4.5e-57 192.8 0.8 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO23692.1 - 1.9e-20 72.8 0.1 4.6e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RRM_1 PF00076.17 EGO23693.1 - 7.5e-08 31.8 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO23693.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO23693.1 - 0.0003 20.5 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EGO23693.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif BTB_2 PF02214.17 EGO23693.1 - 0.081 13.1 0.0 5.9 7.1 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain DNA_Packaging PF11053.3 EGO23693.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Terminase DNA packaging enzyme RRM_5 PF13893.1 EGO23693.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_28 PF00295.12 EGO23694.1 - 2.3e-43 148.4 8.3 3.5e-43 147.8 5.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Methyltransf_31 PF13847.1 EGO23695.1 - 6.5e-21 74.5 0.0 8.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23695.1 - 1.2e-18 67.3 0.0 2.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23695.1 - 3.4e-16 59.3 0.0 5.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO23695.1 - 3.1e-14 52.6 0.0 8.3e-14 51.2 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGO23695.1 - 1.5e-13 51.0 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23695.1 - 5.5e-13 49.4 0.0 8.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23695.1 - 1.9e-09 37.7 0.0 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGO23695.1 - 5.4e-09 35.6 0.0 9.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGO23695.1 - 4.6e-08 32.8 0.0 1e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EGO23695.1 - 1.8e-07 30.7 0.0 3.3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EGO23695.1 - 3.6e-06 25.9 0.0 4.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EGO23695.1 - 8.8e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23695.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO23695.1 - 0.00013 21.1 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGO23695.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EGO23695.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.14 EGO23695.1 - 0.01 15.8 0.1 0.15 12.0 0.0 2.5 2 1 0 2 2 2 1 FtsJ-like methyltransferase DREV PF05219.7 EGO23695.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.3 1 1 0 1 1 1 0 DREV methyltransferase Fibrillarin PF01269.12 EGO23695.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin DOT1 PF08123.8 EGO23695.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_7 PF03492.10 EGO23695.1 - 0.043 12.5 0.0 4.1 6.0 0.0 2.3 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase GCD14 PF08704.5 EGO23695.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit LRR_4 PF12799.2 EGO23698.1 - 1.1e-26 91.9 34.9 6.9e-05 22.3 2.0 8.7 5 2 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO23698.1 - 4.8e-20 71.0 35.6 1.4e-05 24.7 3.9 6.9 3 1 3 7 7 7 7 Leucine rich repeat LRR_9 PF14580.1 EGO23698.1 - 2.2e-06 27.3 10.5 0.85 9.1 0.0 4.7 2 1 1 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.28 EGO23698.1 - 0.00019 21.0 37.0 9.2 6.7 0.2 11.0 10 2 1 11 11 11 2 Leucine Rich Repeat LRR_7 PF13504.1 EGO23698.1 - 0.00028 20.5 38.5 3 8.4 0.3 11.8 13 1 1 14 14 14 3 Leucine rich repeat LRR_6 PF13516.1 EGO23698.1 - 0.3 11.2 29.3 3.1 8.1 0.7 8.8 7 2 2 9 9 9 0 Leucine Rich repeat LRR_3 PF07725.7 EGO23698.1 - 1.5 8.7 3.3 12 5.9 0.1 3.4 2 0 0 2 2 2 0 Leucine Rich Repeat Homeobox_KN PF05920.6 EGO23699.1 - 1.9e-17 62.6 0.1 1.9e-17 62.6 0.1 3.7 4 0 0 4 4 4 1 Homeobox KN domain Homeobox PF00046.24 EGO23699.1 - 2.1e-05 24.0 0.0 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain p450 PF00067.17 EGO23700.1 - 3.4e-65 220.3 0.0 5.7e-65 219.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_32 PF13679.1 EGO23701.1 - 2.1e-22 79.3 1.0 1.4e-21 76.6 0.7 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23701.1 - 0.016 15.6 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23701.1 - 0.041 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGO23701.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23701.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGO23701.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HVSL PF09749.4 EGO23702.1 - 3e-38 131.1 0.0 4.7e-37 127.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EGO23702.1 - 2.2e-08 33.9 0.8 3.8e-08 33.1 0.6 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily cobW PF02492.14 EGO23703.1 - 1.3e-33 115.9 0.0 1.6e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGO23703.1 - 0.0018 17.1 0.1 0.23 10.2 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_18 PF13238.1 EGO23703.1 - 0.0021 18.3 0.0 0.0046 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO23703.1 - 0.0029 17.5 0.0 0.0068 16.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EGO23703.1 - 0.0044 17.8 0.9 0.0081 16.9 0.1 1.9 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO23703.1 - 0.007 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGO23703.1 - 0.038 13.3 0.1 0.094 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO23703.1 - 0.05 13.9 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EGO23703.1 - 0.056 12.8 0.1 1.6 8.1 0.1 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TIP49 PF06068.8 EGO23703.1 - 0.064 11.9 0.0 0.091 11.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 EGO23703.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGO23703.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Aldo_ket_red PF00248.16 EGO23704.1 - 3.4e-61 206.5 0.3 3.9e-61 206.3 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_syn_2C PF08485.5 EGO23704.1 - 0.093 12.2 0.3 0.28 10.7 0.2 1.8 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal DUF1762 PF08574.5 EGO23705.1 - 2.2e-10 40.7 5.2 2.2e-10 40.7 3.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) DUF2500 PF10694.4 EGO23705.1 - 0.062 13.3 0.7 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) His_Phos_2 PF00328.17 EGO23706.1 - 8.5e-08 31.9 0.0 1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HCO3_cotransp PF00955.16 EGO23707.1 - 8.8e-58 196.2 5.6 6e-32 110.9 0.3 3.0 2 1 1 3 3 3 3 HCO3- transporter family Abhydrolase_6 PF12697.2 EGO23708.1 - 1.3e-19 71.0 0.5 2e-19 70.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO23708.1 - 6.6e-18 64.8 0.7 1.9e-17 63.3 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO23708.1 - 5.4e-09 35.9 0.1 9.2e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO23708.1 - 7.6e-08 32.1 0.1 3.2e-06 26.8 0.0 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO23708.1 - 8.4e-06 25.3 0.1 0.00048 19.6 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EGO23708.1 - 4.2e-05 23.0 0.0 0.0095 15.4 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EGO23708.1 - 0.00036 20.8 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 EGO23708.1 - 0.001 18.3 0.1 0.78 8.9 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EGO23708.1 - 0.0013 18.1 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.20 EGO23708.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 EGO23708.1 - 0.0025 16.7 0.1 0.0087 14.9 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 EGO23708.1 - 0.0054 16.1 0.2 1.1 8.6 0.0 3.0 1 1 0 2 2 2 1 Putative esterase PGAP1 PF07819.8 EGO23708.1 - 0.0084 15.7 0.1 0.022 14.3 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EGO23708.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF818 PF05677.7 EGO23708.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Ser_hydrolase PF06821.8 EGO23708.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PAF-AH_p_II PF03403.8 EGO23708.1 - 0.024 12.9 0.1 0.95 7.6 0.1 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1057 PF06342.7 EGO23708.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF3089 PF11288.3 EGO23708.1 - 0.079 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.3 EGO23708.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase HATPase_c PF02518.21 EGO23709.1 - 3.3e-23 81.5 0.1 6.1e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.15 EGO23709.1 - 6.5e-21 74.2 0.0 1.1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.19 EGO23709.1 - 9e-18 64.3 0.1 1.7e-16 60.1 0.1 2.8 2 1 0 2 2 2 1 Response regulator receiver domain GAF PF01590.21 EGO23709.1 - 1.4e-15 57.7 0.1 5.1e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EGO23709.1 - 4e-12 45.9 0.9 4e-12 45.9 0.6 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EGO23709.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.20 EGO23710.1 - 2e-29 102.6 0.1 5.6e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23710.1 - 4.8e-08 33.0 0.0 6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO23710.1 - 8.8e-08 32.0 0.0 2.4e-07 30.5 0.0 1.8 2 1 0 2 2 2 1 KR domain DUF1776 PF08643.5 EGO23710.1 - 5.9e-05 22.3 0.0 8.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGO23710.1 - 0.00033 20.1 0.0 0.00058 19.3 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DNA_ligase_OB PF03120.11 EGO23710.1 - 0.077 12.6 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Eno-Rase_NADH_b PF12242.3 EGO23710.1 - 0.085 12.6 3.0 0.081 12.7 0.8 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldo_ket_red PF00248.16 EGO23712.1 - 1.5e-16 60.1 0.0 1.7e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UNC119_bdg PF15435.1 EGO23712.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue DUF1688 PF07958.6 EGO23712.1 - 0.071 11.6 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) DUF202 PF02656.10 EGO23713.1 - 4.8e-19 68.3 0.4 4.8e-19 68.3 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MORN PF02493.15 EGO23715.1 - 0.076 12.7 0.7 0.66 9.8 0.1 2.5 2 0 0 2 2 2 0 MORN repeat MMR_HSR1 PF01926.18 EGO23716.1 - 0.00012 22.0 0.1 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO23716.1 - 0.00038 19.6 0.2 0.00072 18.7 0.1 1.4 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.22 EGO23716.1 - 0.0074 16.5 0.8 0.014 15.6 0.5 1.6 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EGO23716.1 - 0.0086 15.2 0.1 0.023 13.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO23716.1 - 0.065 13.0 0.2 0.12 12.1 0.1 1.6 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.1 EGO23716.1 - 1.8 8.1 4.6 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain F-box-like PF12937.2 EGO23717.1 - 0.013 15.1 0.2 0.042 13.5 0.1 1.9 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 EGO23718.1 - 4.5e-47 160.4 14.1 6.3e-47 159.9 9.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO23718.1 - 6.9e-08 31.4 23.0 2e-06 26.6 5.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 EGO23718.1 - 0.019 13.0 4.2 0.047 11.7 1.2 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.1 EGO23718.1 - 0.11 11.9 4.2 2.4 7.5 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2883 PF11097.3 EGO23718.1 - 0.22 11.6 0.3 0.47 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) DUF3353 PF11833.3 EGO23718.1 - 1.6 8.1 9.3 0.84 9.0 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF2207 PF09972.4 EGO23718.1 - 3.3 6.1 6.1 0.25 9.8 0.5 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DNA_pol_A_exo1 PF01612.15 EGO23719.1 - 9.4e-46 155.4 0.1 1.5e-45 154.8 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EGO23719.1 - 2.4e-14 53.3 1.9 9.6e-14 51.4 1.0 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EGO23719.1 - 2.1e-10 40.1 0.0 5.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 HRDC domain FIST PF08495.5 EGO23720.1 - 2.4e-06 26.8 0.1 5.5e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 FIST N domain ETF PF01012.16 EGO23721.1 - 1e-35 122.8 0.8 1.4e-35 122.4 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ADH_zinc_N PF00107.21 EGO23721.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CoA_transf_3 PF02515.12 EGO23722.1 - 3.4e-42 143.8 0.0 4.9e-36 123.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Peptidase_M16 PF00675.15 EGO23723.1 - 5.3e-53 178.7 0.8 9.8e-53 177.9 0.5 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO23723.1 - 7e-31 107.3 0.0 1.3e-28 99.8 0.0 3.6 3 1 0 3 3 3 1 Peptidase M16 inactive domain Pkinase PF00069.20 EGO23724.1 - 1.4e-68 230.8 0.0 1.6e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23724.1 - 2.8e-41 141.2 0.0 3.4e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO23724.1 - 6e-07 28.7 0.0 3.2e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO23724.1 - 0.0032 17.2 0.5 0.62 9.7 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGO23724.1 - 0.0074 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGO23724.1 - 0.027 13.8 0.0 0.23 10.7 0.0 2.2 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EGO23724.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pectinesterase PF01095.14 EGO23725.1 - 4.2e-36 124.0 2.6 1.4e-35 122.2 1.8 1.7 1 1 0 1 1 1 1 Pectinesterase DUF3650 PF12368.3 EGO23725.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) Glyco_hydro_16 PF00722.16 EGO23726.1 - 0.0034 16.6 0.0 0.0085 15.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 T2SJ PF11612.3 EGO23727.1 - 0.00028 20.6 0.1 2.8 7.6 0.0 3.1 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein J DUF3368 PF11848.3 EGO23727.1 - 0.00048 19.6 0.0 0.019 14.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) DUF2680 PF10925.3 EGO23727.1 - 0.0043 16.8 0.0 2.9 7.8 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF2680) Ipi1_N PF12333.3 EGO23727.1 - 0.0087 16.0 3.6 0.51 10.3 0.7 2.7 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Noc2 PF03715.8 EGO23727.1 - 0.018 13.9 0.6 0.028 13.2 0.0 1.6 2 0 0 2 2 2 0 Noc2p family Cactin_mid PF10312.4 EGO23727.1 - 0.1 11.8 5.6 5.8 6.1 0.1 3.1 2 1 0 3 3 3 0 Conserved mid region of cactin DegQ PF08181.6 EGO23727.1 - 0.12 12.0 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 DegQ (SacQ) family TMF_TATA_bd PF12325.3 EGO23727.1 - 0.16 11.7 3.6 0.39 10.4 0.2 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Cob_adeno_trans PF01923.13 EGO23727.1 - 0.18 11.5 4.9 1.6 8.4 0.1 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HMGL-like PF00682.14 EGO23727.1 - 0.26 10.9 3.4 7.5 6.1 0.1 2.3 1 1 1 2 2 2 0 HMGL-like Germane PF10646.4 EGO23727.1 - 0.26 11.4 3.7 4.2 7.5 0.1 2.6 1 1 2 3 3 3 0 Sporulation and spore germination WXG100 PF06013.7 EGO23727.1 - 0.3 11.0 5.6 8 6.5 0.1 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Vps53_N PF04100.7 EGO23727.1 - 0.34 9.6 8.5 5.5 5.6 0.2 3.0 1 1 2 3 3 3 0 Vps53-like, N-terminal V-SNARE PF05008.10 EGO23727.1 - 0.73 10.0 6.7 3.1 8.0 0.1 3.6 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus TEX13 PF15186.1 EGO23727.1 - 1.2 8.7 5.3 0.88 9.1 0.5 2.6 2 1 0 3 3 3 0 Testis-expressed sequence 13 protein family NPV_P10 PF05531.7 EGO23727.1 - 2.3 8.5 15.1 18 5.6 2.9 4.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein F_actin_bind PF08919.5 EGO23727.1 - 3.2 7.4 5.8 11 5.7 0.0 2.9 2 1 1 3 3 3 0 F-actin binding HSCB_C PF07743.8 EGO23727.1 - 3.6 8.1 5.3 18 5.9 0.1 3.3 3 2 1 4 4 4 0 HSCB C-terminal oligomerisation domain Pectinesterase PF01095.14 EGO23728.1 - 1.6e-36 125.3 2.0 8.1e-32 109.9 1.5 2.1 1 1 1 2 2 2 2 Pectinesterase Syntaxin_2 PF14523.1 EGO23729.1 - 5.9e-21 74.4 13.0 9.1e-21 73.8 5.0 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGO23729.1 - 2.5e-19 68.7 5.6 4.9e-19 67.7 0.6 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGO23729.1 - 0.00067 19.7 7.9 0.0085 16.2 2.1 2.5 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.16 EGO23729.1 - 0.0056 16.2 1.0 0.0056 16.2 0.7 2.2 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EGO23729.1 - 0.049 13.2 2.0 0.051 13.1 0.1 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF912 PF06024.7 EGO23729.1 - 0.079 13.0 2.7 0.68 10.0 0.1 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) V-SNARE PF05008.10 EGO23729.1 - 0.74 10.0 4.6 0.69 10.1 0.3 3.0 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF3708 PF12501.3 EGO23729.1 - 3.8 7.3 8.0 3.5 7.4 1.4 2.8 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter Pkinase PF00069.20 EGO23733.1 - 1.5e-60 204.5 0.0 2.8e-60 203.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23733.1 - 1.1e-40 139.3 0.0 1.3e-39 135.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO23733.1 - 0.0029 16.6 0.0 0.0084 15.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Ric8 PF10165.4 EGO23733.1 - 0.045 12.5 3.5 1.1 7.9 0.0 2.4 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Ribosomal_L5_C PF00673.16 EGO23734.1 - 7e-15 54.5 0.0 1.9e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Peptidase_M64 PF09471.5 EGO23735.1 - 1.7e-24 86.9 0.0 2.8e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 Ribosomal_L1 PF00687.16 EGO23736.1 - 3.7e-54 183.3 0.3 3.7e-54 183.3 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family HpaP PF09483.5 EGO23736.1 - 7.3 6.5 9.8 11 5.8 6.8 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Abhydrolase_6 PF12697.2 EGO23737.1 - 1.7e-13 50.9 0.1 2.4e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO23737.1 - 3.4e-09 36.5 0.0 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO23737.1 - 3.5e-07 29.6 0.2 6.3e-07 28.8 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGO23737.1 - 9.7e-05 22.0 0.1 0.00049 19.7 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EGO23737.1 - 0.00082 18.3 0.3 0.002 17.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) DUF915 PF06028.6 EGO23737.1 - 0.014 14.5 0.0 0.037 13.1 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Dynamin_N PF00350.18 EGO23740.1 - 1.4e-18 67.2 1.0 3.6e-18 65.9 0.1 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EGO23740.1 - 4.5e-11 42.7 0.0 3.2e-10 39.9 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO23740.1 - 1.3e-07 31.2 0.2 2.6e-06 27.0 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGO23740.1 - 0.00012 22.5 0.3 0.014 15.8 0.2 3.2 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EGO23740.1 - 0.0023 17.4 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.8 EGO23740.1 - 0.019 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EGO23740.1 - 0.051 13.0 0.0 0.19 11.2 0.0 2.0 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EGO23740.1 - 0.19 12.0 2.2 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 AAA domain Aldo_ket_red PF00248.16 EGO23741.1 - 7.4e-63 212.0 0.3 8.4e-63 211.8 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EGO23741.1 - 0.0058 15.2 0.0 0.0085 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Aldo_ket_red PF00248.16 EGO23744.1 - 1.4e-64 217.6 0.2 1.6e-64 217.4 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EGO23744.1 - 0.0025 16.4 0.0 0.0089 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1688) adh_short PF00106.20 EGO23745.1 - 1.1e-15 57.9 0.3 2.8e-12 46.8 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23745.1 - 1.9e-13 50.7 0.0 2.3e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO23745.1 - 1.3e-05 24.9 1.2 2.9e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 KR domain DUF1776 PF08643.5 EGO23745.1 - 0.012 14.7 0.0 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Acyl-CoA_dh_1 PF00441.19 EGO23747.1 - 3.4e-19 69.4 4.9 5.9e-19 68.6 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO23747.1 - 6e-09 36.2 0.8 1.2e-08 35.2 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO23747.1 - 5e-07 29.1 0.2 1e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGO23747.1 - 0.018 15.5 0.0 0.085 13.4 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Aldo_ket_red PF00248.16 EGO23748.1 - 6e-65 218.8 0.2 6.9e-65 218.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EGO23748.1 - 0.0049 15.4 0.0 0.017 13.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1688) zf-CCHC_3 PF13917.1 EGO23749.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO23749.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO23749.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SNAPc19 PF15497.1 EGO23752.1 - 0.061 13.5 1.5 0.066 13.4 1.1 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Aldo_ket_red PF00248.16 EGO23753.1 - 1.1e-64 218.0 0.2 1.2e-64 217.8 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EGO23753.1 - 0.0024 16.4 0.0 0.017 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1688) Dimer_Tnp_hAT PF05699.9 EGO23754.1 - 1.5e-20 72.6 0.3 2e-20 72.2 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FAM196 PF15265.1 EGO23756.1 - 7.5 5.6 13.6 8.8 5.4 9.4 1.0 1 0 0 1 1 1 0 FAM196 family ENTH PF01417.15 EGO23758.1 - 1.3e-44 151.0 0.0 2e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGO23758.1 - 0.006 15.3 0.1 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain MIP-T3 PF10243.4 EGO23758.1 - 0.15 10.5 1.8 0.11 10.9 0.0 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Glyco_hydro_20 PF00728.17 EGO23759.1 - 1.4e-92 310.6 0.1 1.6e-92 310.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGO23759.1 - 8.6e-09 36.1 0.2 7.2e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGO23759.1 - 0.0013 19.2 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RNA_pol_Rpb4 PF03874.11 EGO23760.1 - 3.7e-19 68.8 0.0 4.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 NOT2_3_5 PF04153.13 EGO23761.1 - 1.1e-32 112.6 1.4 1.1e-32 112.6 1.0 2.7 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Prenyltrans PF00432.16 EGO23762.1 - 9e-35 117.9 10.3 3.2e-10 39.3 1.2 5.4 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO23762.1 - 7.4e-26 90.7 0.1 2.2e-11 44.1 0.0 3.2 2 2 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO23762.1 - 2.5e-05 24.2 0.0 0.00046 20.1 0.0 2.8 1 1 2 3 3 3 2 Prenyltransferase-like DZR PF12773.2 EGO23762.1 - 0.07 12.9 1.5 0.43 10.4 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon MIF4G PF02854.14 EGO23763.1 - 0.0049 16.3 0.0 0.0049 16.3 0.0 1.0 1 0 0 1 1 1 1 MIF4G domain Abhydrolase_5 PF12695.2 EGO23765.1 - 0.00024 20.8 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGO23765.1 - 0.00027 20.5 0.0 0.00061 19.4 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO23765.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGO23765.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ELFV_dehydrog PF00208.16 EGO23766.1 - 2.2e-49 168.2 0.0 3.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EGO23766.1 - 1.2e-19 69.4 0.0 1e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EGO23766.1 - 0.043 13.3 0.0 0.099 12.2 0.0 1.6 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain adh_short PF00106.20 EGO23767.1 - 1.5e-23 83.5 0.6 5.5e-22 78.4 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO23767.1 - 4.4e-09 36.4 0.0 1.7e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO23767.1 - 4e-06 26.6 0.1 5.7e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EGO23767.1 - 0.089 12.5 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SAM_2 PF07647.12 EGO23768.1 - 6.9e-09 35.4 0.0 2.4e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGO23768.1 - 6.6e-06 26.2 0.1 2.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Lamprin PF06403.6 EGO23768.1 - 1.4 8.6 6.4 0.2 11.3 1.3 1.8 1 1 1 2 2 2 0 Lamprin DIOX_N PF14226.1 EGO23769.1 - 1.5e-31 109.3 0.0 2.1e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO23769.1 - 1.1e-21 76.9 0.0 2.1e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ADH_zinc_N PF00107.21 EGO23771.1 - 5.8e-24 84.1 0.0 1.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO23771.1 - 1.3e-06 29.2 0.0 2.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EGO23771.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Ank_2 PF12796.2 EGO23772.1 - 6.4e-37 125.7 3.9 6.4e-13 48.8 0.4 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO23772.1 - 1.8e-31 107.9 0.3 5.3e-08 33.1 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO23772.1 - 8e-25 86.3 1.3 8.4e-11 41.7 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO23772.1 - 1.3e-24 83.8 0.3 7.6e-05 22.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.25 EGO23772.1 - 1.3e-22 78.3 4.6 0.00015 21.4 0.0 6.0 5 1 0 5 5 5 4 Ankyrin repeat Retrotrans_gag PF03732.12 EGO23773.1 - 0.00012 22.1 0.0 0.00035 20.5 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 EGO23775.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EGO23776.1 - 9.5e-05 22.3 6.7 0.00039 20.4 4.4 2.3 1 1 0 1 1 1 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.1 EGO23776.1 - 0.0047 16.5 0.5 0.011 15.4 0.3 1.7 1 1 0 1 1 1 1 Sperm tail C-terminal domain Med15_fungi PF05397.7 EGO23776.1 - 0.077 12.9 0.6 0.56 10.1 0.1 2.4 1 1 1 2 2 2 0 Mediator complex subunit 15 Aconitase_2_N PF06434.8 EGO23778.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus ADH_zinc_N PF00107.21 EGO23779.1 - 2e-20 72.6 0.0 4.1e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO23779.1 - 4.3e-07 30.8 0.0 1.3e-06 29.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EGO23779.1 - 0.00035 20.5 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Thi4 PF01946.12 EGO23780.1 - 4.6e-94 313.8 0.1 5.6e-94 313.5 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGO23780.1 - 2.8e-11 42.9 1.1 3.2e-10 39.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO23780.1 - 4.4e-08 32.4 0.4 6.4e-07 28.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO23780.1 - 5.4e-07 29.5 0.1 1.6e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO23780.1 - 2.2e-06 27.7 0.4 4.3e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO23780.1 - 2.7e-06 26.5 1.4 5.7e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGO23780.1 - 5e-06 26.3 2.0 0.00013 21.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EGO23780.1 - 7e-05 22.0 0.2 9.9e-05 21.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO23780.1 - 8.7e-05 22.6 0.1 0.00019 21.5 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO23780.1 - 0.00016 20.2 0.6 0.00033 19.2 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EGO23780.1 - 0.012 14.4 0.2 0.056 12.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 EGO23780.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EGO23780.1 - 0.077 11.6 0.3 0.12 10.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 EGO23780.1 - 0.088 11.7 0.0 0.43 9.4 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Phage_base_V PF04717.7 EGO23781.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Phage-related baseplate assembly protein Med7 PF05983.6 EGO23785.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 MED7 protein YlqD PF11068.3 EGO23787.1 - 0.018 15.0 1.9 0.018 15.0 1.3 1.9 1 1 1 2 2 2 0 YlqD protein DUF4145 PF13643.1 EGO23787.1 - 0.053 13.3 0.2 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) CcmH PF03918.9 EGO23787.1 - 0.11 11.4 1.3 0.21 10.5 0.9 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein MIF4G_like_2 PF09090.6 EGO23787.1 - 0.23 10.6 4.6 0.36 10.0 3.2 1.2 1 0 0 1 1 1 0 MIF4G like TMF_DNA_bd PF12329.3 EGO23787.1 - 0.25 11.1 12.5 1.1 9.1 3.8 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 EGO23787.1 - 0.29 8.9 5.4 0.36 8.6 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EGO23787.1 - 0.79 9.5 17.7 0.15 11.8 4.1 2.4 1 1 1 2 2 2 0 Tropomyosin like APG6 PF04111.7 EGO23787.1 - 1.5 7.7 15.8 0.51 9.3 2.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Acetyltransf_11 PF13720.1 EGO23787.1 - 2 8.7 8.2 15 5.9 1.5 3.1 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DivIC PF04977.10 EGO23787.1 - 2 7.9 14.3 1.1 8.8 3.3 3.7 1 1 3 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 EGO23787.1 - 2.5 7.8 14.9 3.1 7.5 6.1 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein D5_N PF08706.6 EGO23787.1 - 4.9 7.2 6.1 5.5 7.0 3.3 2.0 1 1 1 2 2 2 0 D5 N terminal like IncA PF04156.9 EGO23787.1 - 5.3 6.6 19.5 6.6 6.2 2.4 2.3 1 1 1 2 2 2 0 IncA protein CM_2 PF01817.16 EGO23790.1 - 4.1e-12 46.0 0.1 9.2e-07 28.8 0.0 3.9 3 1 0 3 3 3 2 Chorismate mutase type II RPAP1_N PF08621.5 EGO23790.1 - 0.12 11.9 1.4 4 7.1 0.0 3.0 4 0 0 4 4 4 0 RPAP1-like, N-terminal Septin PF00735.13 EGO23791.1 - 2.7e-47 161.1 0.2 3.9e-17 62.1 0.1 3.3 3 1 0 3 3 3 3 Septin GTP_EFTU PF00009.22 EGO23791.1 - 9.1e-06 25.2 0.0 4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EGO23791.1 - 0.00019 21.4 1.6 0.00049 20.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO23791.1 - 0.00023 21.0 0.0 0.00056 19.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO23791.1 - 0.0031 18.0 0.0 0.0061 17.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGO23791.1 - 0.0055 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EGO23791.1 - 0.0061 16.4 0.4 2.4 7.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AAA_33 PF13671.1 EGO23791.1 - 0.027 14.3 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO23791.1 - 0.033 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EGO23791.1 - 0.07 12.4 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF258 PF03193.11 EGO23791.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 EGO23791.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.5 EGO23791.1 - 0.14 11.3 0.0 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EGO23792.1 - 2.3e-30 105.5 0.0 4.4e-10 39.0 0.1 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 EGO23792.1 - 3.3e-10 39.7 9.9 3.3e-10 39.7 6.8 3.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EGO23793.1 - 5.5e-10 38.9 10.6 9.5e-10 38.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.16 EGO23795.1 - 2.4e-201 669.6 0.1 2.8e-201 669.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DUF912 PF06024.7 EGO23796.1 - 0.0032 17.4 0.2 0.0079 16.2 0.0 1.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF61 PF01886.11 EGO23796.1 - 0.05 13.4 0.1 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF61 Tmemb_18A PF09771.4 EGO23796.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 DUF4504 PF14953.1 EGO23800.1 - 1.6e-05 24.3 0.1 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Pro_isomerase PF00160.16 EGO23801.1 - 1.5e-47 161.7 0.1 2.6e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGO23801.1 - 8.6e-10 38.1 0.8 8e-05 22.3 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-AN1 PF01428.11 EGO23802.1 - 1e-12 47.6 19.6 6.1e-12 45.2 4.7 2.8 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EGO23802.1 - 0.92 9.7 7.6 0.1 12.8 1.5 2.2 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain SR-25 PF10500.4 EGO23802.1 - 4.7 6.6 17.3 6.9 6.0 12.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IBR PF01485.16 EGO23802.1 - 6.2 6.7 11.6 12 5.8 7.7 1.8 1 1 0 1 1 1 0 IBR domain Peptidase_S64 PF08192.6 EGO23802.1 - 6.5 4.9 8.5 8.4 4.5 5.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 His_Phos_1 PF00300.17 EGO23803.1 - 1.1e-29 103.5 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Troponin-I_N PF11636.3 EGO23803.1 - 0.13 11.9 0.2 0.28 10.9 0.2 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 Eaf7 PF07904.8 EGO23804.1 - 7.7e-14 51.4 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Arrestin_C PF02752.17 EGO23805.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain HECT PF00632.20 EGO23806.1 - 1.4e-90 303.6 0.0 2.2e-90 303.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EGO23806.1 - 2.7e-34 116.6 20.7 1e-12 47.6 0.7 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EGO23806.1 - 1.1e-13 50.8 0.0 2.7e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain RasGEF_N PF00618.15 EGO23807.1 - 8.7e-20 70.7 0.3 8.2e-18 64.4 0.0 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif RasGEF PF00617.14 EGO23807.1 - 4.1e-14 52.7 0.0 7.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Ribosomal_L22 PF00237.14 EGO23808.1 - 9.1e-30 102.7 0.1 1.4e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RICTOR_N PF14664.1 EGO23809.1 - 1.2e-91 307.1 0.1 2.4e-91 306.0 0.1 1.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EGO23809.1 - 7.3e-81 270.4 0.2 1.7e-79 265.9 0.0 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EGO23809.1 - 6.6e-33 113.0 1.3 1.9e-31 108.3 0.0 3.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EGO23809.1 - 1.5e-28 98.5 0.0 8.3e-27 92.9 0.0 3.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EGO23809.1 - 1e-07 31.5 2.7 2.5e-07 30.3 1.9 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 EGO23809.1 - 0.0003 20.5 2.9 3 8.1 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EGO23809.1 - 0.00056 20.1 3.0 1 9.6 0.0 4.5 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EGO23809.1 - 0.0075 16.7 0.0 17 6.0 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat Uds1 PF15456.1 EGO23809.1 - 0.5 10.3 3.8 0.4 10.6 0.3 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Pyr_redox_3 PF13738.1 EGO23810.1 - 1.9e-17 64.0 0.0 2.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO23810.1 - 1.1e-15 56.8 0.1 2.4e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGO23810.1 - 6e-08 32.7 0.0 5.4e-06 26.4 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO23810.1 - 3.6e-07 29.4 0.0 1.6e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO23810.1 - 2.5e-06 27.3 0.0 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ETC_C1_NDUFA4 PF04800.7 EGO23811.1 - 1.8e-36 123.9 0.5 2.5e-36 123.5 0.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF221 PF02714.10 EGO23812.1 - 5.1e-50 170.1 17.6 8.1e-50 169.5 12.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO23812.1 - 1e-14 54.3 1.5 2.8e-14 52.9 0.2 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGO23812.1 - 1.2e-06 28.8 0.1 0.0074 16.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EGO23812.1 - 0.0032 17.4 0.1 0.28 11.1 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO23812.1 - 0.065 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WBP-1 PF11669.3 EGO23812.1 - 0.067 13.2 0.1 27 4.9 0.0 3.2 2 0 0 2 2 2 0 WW domain-binding protein 1 RRM_1 PF00076.17 EGO23812.1 - 0.15 11.6 0.1 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBM_1 PF00734.13 EGO23813.1 - 1.1e-11 44.1 8.6 3.2e-11 42.6 6.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Sod_Cu PF00080.15 EGO23814.1 - 5.2e-45 153.0 1.2 6.2e-45 152.8 0.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Motile_Sperm PF00635.21 EGO23815.1 - 1.4e-26 92.2 0.2 3.1e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF3481 PF11980.3 EGO23817.1 - 7.5 6.4 8.0 0.29 10.9 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) ABM PF03992.11 EGO23818.1 - 0.0097 15.9 0.0 0.095 12.7 0.0 2.1 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Mito_carr PF00153.22 EGO23819.1 - 1.7e-43 146.2 3.3 1.2e-16 60.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MutS_V PF00488.16 EGO23820.1 - 3e-49 167.5 0.1 4.6e-48 163.6 0.0 2.6 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EGO23820.1 - 3.3e-35 121.7 0.0 6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGO23820.1 - 0.0068 16.5 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EGO23820.1 - 0.017 15.0 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO23820.1 - 0.02 15.0 0.0 0.059 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.20 EGO23821.1 - 6.2e-20 71.8 0.6 9.1e-20 71.3 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.9 EGO23822.1 - 3.2e-36 122.6 6.5 5.3e-20 70.7 1.4 2.8 2 0 0 2 2 2 2 PQ loop repeat F-box-like PF12937.2 EGO23823.1 - 0.00078 19.1 0.3 0.00078 19.1 0.2 2.9 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.28 EGO23823.1 - 0.38 10.9 4.0 14 6.1 0.0 4.9 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 EGO23823.1 - 2.5 7.8 6.4 1.8e+02 1.8 3.0 4.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF1144 PF06610.8 EGO23824.1 - 0.15 11.7 4.3 3.2 7.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1144) DUF1240 PF06836.7 EGO23824.1 - 1.7 8.9 7.6 9.2 6.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF1435 PF07256.7 EGO23824.1 - 3 7.8 8.2 0.26 11.3 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1435) zf-TFIIB PF13453.1 EGO23826.1 - 0.09 11.9 2.1 0.14 11.3 0.1 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger PRCH PF03967.8 EGO23828.1 - 0.041 13.4 0.3 0.15 11.6 0.2 1.9 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region YpzG PF14139.1 EGO23829.1 - 0.041 13.8 0.9 0.12 12.3 0.6 1.7 1 0 0 1 1 1 0 YpzG-like protein Gcd10p PF04189.8 EGO23835.1 - 0.087 11.9 1.3 0.11 11.5 0.9 1.1 1 0 0 1 1 1 0 Gcd10p family Unstab_antitox PF09720.5 EGO23837.1 - 0.036 13.7 0.9 0.048 13.3 0.5 1.4 1 1 0 1 1 1 0 Putative addiction module component DUF2663 PF10864.3 EGO23838.1 - 0.071 13.3 1.8 0.14 12.4 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Pkinase_C PF00433.19 EGO23839.1 - 1.2e-08 35.2 0.2 1.8e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase C terminal domain DDE_Tnp_4 PF13359.1 EGO23840.1 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease LacI PF00356.16 EGO23840.1 - 0.042 13.4 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF4541 PF15074.1 EGO23841.1 - 0.05 14.1 0.9 0.1 13.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) TDH PF03347.8 EGO23842.1 - 0.03 13.8 0.3 0.053 13.0 0.2 1.5 1 1 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF809 PF05663.6 EGO23844.1 - 1.5 8.7 8.5 2.7 7.9 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF666 PF05006.7 EGO23845.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF666) DUF350 PF03994.9 EGO23845.1 - 0.13 12.0 1.3 0.22 11.3 0.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) Retrotrans_gag PF03732.12 EGO23847.1 - 0.024 14.6 0.1 0.067 13.2 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3527 PF12043.3 EGO23848.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) rve PF00665.21 EGO23849.1 - 0.00019 21.5 0.1 0.00064 19.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO23849.1 - 0.0056 16.5 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 DUF4219 PF13961.1 EGO23850.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Pkinase PF00069.20 EGO23853.1 - 2.7e-69 233.2 0.0 3.4e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO23853.1 - 1.9e-31 109.0 0.0 2.7e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGO23853.1 - 2.2e-09 37.6 1.7 5.1e-09 36.5 1.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO23853.1 - 9.5e-05 21.4 0.0 0.00021 20.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGO23853.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO23853.1 - 0.032 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGO23853.1 - 0.13 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Proteasome PF00227.21 EGO23854.1 - 3.3e-50 170.0 0.1 4.1e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit ABC_membrane PF00664.18 EGO23855.1 - 1.6e-90 303.2 28.0 3.8e-48 164.2 5.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO23855.1 - 6e-69 230.6 0.1 1e-33 116.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EGO23855.1 - 2.8e-14 53.7 0.1 2.7e-05 24.2 0.0 4.5 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGO23855.1 - 3.7e-14 52.4 1.3 0.00026 20.3 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGO23855.1 - 1e-10 40.8 0.5 0.00015 20.5 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGO23855.1 - 1.8e-08 33.8 1.0 0.0044 16.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO23855.1 - 6.9e-08 33.3 0.0 0.0071 17.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO23855.1 - 2e-07 31.1 3.8 0.00072 19.5 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGO23855.1 - 9e-06 24.9 0.0 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGO23855.1 - 2.7e-05 24.5 0.0 0.055 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EGO23855.1 - 0.00012 21.7 0.2 5.6 6.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 EGO23855.1 - 0.00013 22.1 4.6 0.16 12.1 0.1 4.2 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EGO23855.1 - 0.00021 21.1 0.0 0.58 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGO23855.1 - 0.00024 20.9 2.4 0.84 9.6 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 EGO23855.1 - 0.00033 19.4 0.0 0.093 11.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.1 EGO23855.1 - 0.00045 20.6 0.2 2.5 8.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EGO23855.1 - 0.0006 19.2 2.2 0.73 9.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain DUF3987 PF13148.1 EGO23855.1 - 0.0019 16.8 0.2 0.41 9.1 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) AAA_5 PF07728.9 EGO23855.1 - 0.0027 17.4 0.0 4.1 7.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) MobB PF03205.9 EGO23855.1 - 0.0031 17.2 0.2 1.8 8.2 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGO23855.1 - 0.0043 16.5 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EGO23855.1 - 0.0044 16.1 0.0 3.5 6.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 EGO23855.1 - 0.0049 16.7 0.1 4.3 7.0 0.2 3.1 2 0 0 2 2 2 1 Domain of unknown function DUF87 PRK PF00485.13 EGO23855.1 - 0.006 16.1 0.0 1.4 8.3 0.0 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EGO23855.1 - 0.0079 16.1 0.2 2.6 7.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.15 EGO23855.1 - 0.011 15.4 0.1 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EGO23855.1 - 0.02 14.8 0.0 5.8 6.9 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_15 PF13175.1 EGO23855.1 - 0.022 13.8 0.0 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EGO23855.1 - 0.027 13.9 4.0 5.3 6.3 0.0 3.7 5 0 0 5 5 4 0 AAA-like domain Dynamin_N PF00350.18 EGO23855.1 - 0.038 13.8 0.1 10 5.9 0.0 3.4 3 0 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 EGO23855.1 - 0.13 12.3 0.0 15 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EGO23855.1 - 0.2 10.4 0.0 7.4 5.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EGO23858.1 - 1.1e-40 138.9 0.0 2.1e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO23858.1 - 1.9e-05 24.7 0.1 0.002 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO23858.1 - 0.0002 21.5 0.7 0.016 15.3 0.5 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO23858.1 - 0.00064 18.8 0.0 0.002 17.2 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGO23858.1 - 0.00076 19.2 0.2 0.006 16.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO23858.1 - 0.00087 19.2 0.0 0.012 15.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EGO23858.1 - 0.0048 16.1 0.1 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 EGO23858.1 - 0.0071 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EGO23858.1 - 0.0088 15.9 0.1 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO23858.1 - 0.0089 15.7 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EGO23858.1 - 0.013 14.6 0.1 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGO23858.1 - 0.017 14.5 1.2 0.52 9.6 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO23858.1 - 0.019 15.8 0.0 0.045 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO23858.1 - 0.032 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGO23858.1 - 0.05 12.5 0.0 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EGO23858.1 - 0.059 13.0 0.3 3.5 7.2 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.1 EGO23858.1 - 0.082 12.4 0.4 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain NuA4 PF09340.5 EGO23859.1 - 3.8e-23 80.9 0.2 3.8e-23 80.9 0.1 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Mod_r PF07200.8 EGO23861.1 - 4.2e-25 88.4 11.7 2.2e-24 86.0 8.1 1.8 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF2051 PF09738.4 EGO23861.1 - 0.00012 21.4 1.5 0.00015 21.2 0.4 1.5 1 1 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) CSTF2_hinge PF14327.1 EGO23861.1 - 0.14 12.2 0.2 0.5 10.4 0.2 1.9 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 GAS PF13851.1 EGO23861.1 - 0.58 9.3 5.7 0.6 9.2 2.6 1.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HMG_box PF00505.14 EGO23861.1 - 1.5 9.1 5.1 0.42 10.9 0.2 2.4 3 0 0 3 3 3 0 HMG (high mobility group) box DUF904 PF06005.7 EGO23861.1 - 2.5 8.4 8.5 5.4 7.3 3.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) p450 PF00067.17 EGO23862.1 - 2.6e-74 250.4 0.0 2.9e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec7 PF01369.15 EGO23863.1 - 8e-35 120.2 0.0 1.4e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGO23863.1 - 2.9e-15 56.4 0.0 5.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGO23863.1 - 4.5e-10 39.6 0.2 1.1e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 PH domain Methyltransf_11 PF08241.7 EGO23864.1 - 2.3e-07 31.1 0.0 2.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO23864.1 - 1.5e-05 24.2 0.0 1.6e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO23864.1 - 2.6e-05 24.4 0.0 3.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23864.1 - 0.003 17.2 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO23864.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.11 EGO23864.1 - 0.072 11.4 0.0 0.083 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EGO23864.1 - 0.089 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23864.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23864.1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain zf-C3H1 PF10650.4 EGO23867.1 - 0.0021 17.5 0.5 0.0041 16.5 0.3 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain adh_short PF00106.20 EGO23870.1 - 1.3e-22 80.5 0.1 2.8e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO23870.1 - 2.3e-10 40.4 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO23870.1 - 7.8e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO23870.1 - 1.4e-05 25.1 0.1 2.6e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO23870.1 - 0.0017 17.8 0.1 0.0029 17.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGO23870.1 - 0.0043 17.1 0.2 0.008 16.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EGO23870.1 - 0.0069 15.4 0.3 0.0096 14.9 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EGO23870.1 - 0.018 14.3 0.2 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EGO23870.1 - 0.054 12.4 0.1 0.071 12.0 0.1 1.3 1 1 0 1 1 1 0 Male sterility protein 2-Hacid_dh_C PF02826.14 EGO23870.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EGO23870.1 - 0.085 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TIR-like PF10137.4 EGO23870.1 - 0.15 11.7 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain VWA_2 PF13519.1 EGO23871.1 - 1.5e-10 41.4 0.0 3.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO23871.1 - 0.00019 21.1 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 EGO23871.1 - 0.0049 15.9 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Miro PF08477.8 EGO23872.1 - 2.7e-36 124.6 0.0 4.7e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EGO23872.1 - 1.1e-33 114.8 0.0 2.2e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EGO23872.1 - 5e-32 110.5 0.0 4.2e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 EGO23872.1 - 4e-30 102.9 0.1 9.5e-30 101.7 0.1 1.7 1 0 0 1 1 1 1 EF hand associated Arf PF00025.16 EGO23872.1 - 1.6e-10 40.5 0.0 0.00013 21.2 0.0 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 EGO23872.1 - 9.5e-09 35.4 0.0 0.0086 16.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain EF-hand_6 PF13405.1 EGO23872.1 - 1.1e-08 34.2 0.6 0.0011 18.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGO23872.1 - 1.4e-08 33.4 1.7 0.00037 19.6 0.0 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 EGO23872.1 - 1.7e-08 34.4 0.0 0.00045 20.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EGO23872.1 - 4.2e-08 33.2 0.4 0.0041 17.2 0.0 2.8 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO23872.1 - 1.3e-06 27.4 4.9 0.00098 18.3 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 EGO23872.1 - 1.8e-06 28.0 0.0 0.062 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 EGO23872.1 - 8.5e-06 25.8 0.0 0.057 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EGO23872.1 - 1.6e-05 24.6 0.2 0.096 12.3 0.1 2.3 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EGO23872.1 - 2.9e-05 23.9 0.6 0.85 9.4 0.0 3.3 2 1 1 3 3 3 1 Dynamin family AAA_29 PF13555.1 EGO23872.1 - 5e-05 22.7 0.0 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGO23872.1 - 6.9e-05 23.1 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.7 EGO23872.1 - 7.3e-05 22.4 0.1 0.27 10.8 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 EGO23872.1 - 9.3e-05 22.7 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO23872.1 - 0.00011 22.4 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EGO23872.1 - 0.00025 20.5 0.0 0.087 12.3 0.0 2.7 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGO23872.1 - 0.00029 20.4 0.0 0.7 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGO23872.1 - 0.00043 20.1 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO23872.1 - 0.0005 19.3 0.0 0.099 11.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EGO23872.1 - 0.00087 19.4 0.0 0.73 10.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.12 EGO23872.1 - 0.00093 18.8 2.3 3.3 7.1 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGO23872.1 - 0.00093 20.0 0.0 1.1 10.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain SRPRB PF09439.5 EGO23872.1 - 0.00098 18.3 0.0 1.5 8.0 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit VirE PF05272.6 EGO23872.1 - 0.001 18.5 0.1 2.2 7.6 0.0 3.4 3 0 0 3 3 3 1 Virulence-associated protein E EF-hand_10 PF14788.1 EGO23872.1 - 0.0017 17.9 3.7 0.0092 15.6 0.1 2.4 2 0 0 2 2 2 1 EF hand Septin PF00735.13 EGO23872.1 - 0.0022 17.0 0.0 0.054 12.4 0.0 2.2 2 0 0 2 2 2 1 Septin FtsK_SpoIIIE PF01580.13 EGO23872.1 - 0.003 17.0 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EGO23872.1 - 0.0032 16.8 0.0 0.44 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EGO23872.1 - 0.0035 16.7 0.1 2.1 7.7 0.0 3.7 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EGO23872.1 - 0.004 16.1 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SPARC_Ca_bdg PF10591.4 EGO23872.1 - 0.0051 16.8 0.1 0.62 10.1 0.0 2.6 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_5 PF07728.9 EGO23872.1 - 0.0067 16.1 0.0 0.23 11.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EGO23872.1 - 0.008 15.9 0.1 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase Viral_helicase1 PF01443.13 EGO23872.1 - 0.0089 15.5 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 EGO23872.1 - 0.013 14.2 0.0 1.8 7.1 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_23 PF13476.1 EGO23872.1 - 0.019 15.3 0.1 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EGO23872.1 - 0.022 14.2 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EGO23872.1 - 0.031 13.9 0.0 4 7.0 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EGO23872.1 - 0.036 13.9 0.0 9.5 6.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGO23872.1 - 0.036 12.9 0.0 4.8 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 EGO23872.1 - 0.055 12.9 0.1 2.7 7.4 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 EGO23872.1 - 0.056 12.5 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 1 0 AIG1 family MCM PF00493.18 EGO23872.1 - 0.066 12.0 0.1 0.25 10.0 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family EF-hand_8 PF13833.1 EGO23872.1 - 0.084 12.5 1.0 18 5.0 0.1 3.2 3 0 0 3 3 2 0 EF-hand domain pair Guanylate_kin PF00625.16 EGO23872.1 - 0.11 11.9 0.1 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase NOG1 PF06858.9 EGO23872.1 - 0.13 12.2 0.3 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Gtr1_RagA PF04670.7 EGO23872.1 - 0.14 11.2 0.0 15 4.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Zeta_toxin PF06414.7 EGO23872.1 - 0.14 11.2 0.0 8 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 EGO23872.1 - 0.15 11.5 0.0 2.2 7.7 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGO23872.1 - 0.19 11.2 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EGO23872.1 - 0.22 10.0 0.0 13 4.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RasGEF PF00617.14 EGO23873.1 - 1.8e-49 168.0 0.0 3.6e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO23873.1 - 1.4e-20 73.3 0.0 3.7e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EGO23873.1 - 2.3e-14 52.6 0.0 4.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO23873.1 - 3.8e-13 48.6 0.1 8.8e-13 47.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO23873.1 - 1.3e-12 46.9 0.0 2.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain MBOAT_2 PF13813.1 EGO23874.1 - 9.3e-14 51.2 3.9 1.6e-13 50.4 1.2 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1477 PF07346.6 EGO23874.1 - 0.1 12.6 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) p450 PF00067.17 EGO23875.1 - 4.8e-73 246.2 0.0 6.1e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO23876.1 - 4.7e-66 223.1 0.0 5.7e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO23877.1 - 7.2e-40 136.8 0.0 1.1e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO23878.1 - 4.3e-64 216.7 0.0 5.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDC37_N PF03234.9 EGO23879.1 - 1.8e-46 158.7 2.0 1.8e-46 158.7 1.4 2.4 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EGO23879.1 - 8.2e-28 97.0 3.0 4e-27 94.7 0.0 2.7 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EGO23879.1 - 1.7e-18 66.3 0.1 1.7e-18 66.3 0.1 2.8 3 0 0 3 3 3 1 Cdc37 C terminal domain Baculo_PEP_N PF04512.7 EGO23879.1 - 0.015 15.2 0.2 4.3 7.3 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, N terminus Adaptin_binding PF10199.4 EGO23883.1 - 2.6e-10 40.7 0.4 0.00062 20.0 0.0 3.3 3 0 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 RVP_2 PF08284.6 EGO23885.1 - 0.00027 20.8 0.0 0.1 12.5 0.0 2.1 1 1 1 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO23885.1 - 0.0041 17.5 0.0 0.0061 17.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO23885.1 - 0.0057 16.4 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Nnf1 PF03980.9 EGO23885.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Nnf1 zf-CCHC PF00098.18 EGO23886.1 - 1.4e-07 31.1 0.5 1.9e-07 30.6 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO23886.1 - 0.0029 17.2 0.5 0.0046 16.5 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO23886.1 - 0.0058 16.2 0.6 0.0088 15.6 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle ThiW PF09512.5 EGO23892.1 - 8.8 6.1 13.3 0.044 13.6 2.8 1.9 3 0 0 3 3 3 0 Thiamine-precursor transporter protein (ThiW) DUF4584 PF15223.1 EGO23894.1 - 0.079 12.2 0.4 0.088 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) HEAT_2 PF13646.1 EGO23895.1 - 2.5e-37 127.0 0.8 1.7e-14 53.8 0.0 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EGO23895.1 - 6.6e-23 78.8 0.0 0.00052 20.2 0.0 6.7 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 EGO23895.1 - 3.5e-13 48.4 0.1 0.038 14.0 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EGO23895.1 - 3.6e-10 40.0 0.7 0.0066 16.9 0.0 5.2 2 2 2 4 4 4 4 HEAT-like repeat Arm PF00514.18 EGO23895.1 - 7.2e-05 22.4 0.1 0.14 12.0 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF438 PF04282.8 EGO23895.1 - 0.02 14.6 0.0 2.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF438) Ribosomal_L10 PF00466.15 EGO23896.1 - 2e-17 62.9 0.0 2.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_S9 PF00326.16 EGO23897.1 - 5e-47 159.8 0.2 7.5e-47 159.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO23897.1 - 1.2e-09 38.0 0.0 3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGO23897.1 - 0.1 11.0 0.1 3.2 6.1 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EGO23898.1 - 4e-38 130.7 0.2 1.6e-37 128.8 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO23898.1 - 6.7e-07 29.1 0.0 3.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGO23898.1 - 0.00014 20.5 0.0 0.025 13.0 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EGO23898.1 - 0.0037 17.1 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1993 PF09351.5 EGO23898.1 - 0.08 12.8 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) TraK PF06586.6 EGO23899.1 - 0.059 12.4 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 TraK protein FlgM PF04316.8 EGO23899.1 - 0.076 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Flagellin_C PF00700.16 EGO23899.1 - 0.12 12.5 0.2 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Uso1_p115_C PF04871.8 EGO23900.1 - 0.11 12.4 16.5 1.3 8.9 2.9 3.4 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sec1 PF00995.18 EGO23901.1 - 6.3e-142 474.0 0.1 7.7e-142 473.7 0.1 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.7 EGO23901.1 - 5.2e-65 219.1 0.2 3e-64 216.6 0.2 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGO23901.1 - 1.8e-26 91.9 0.2 4.7e-26 90.5 0.2 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) OGFr_N PF04664.8 EGO23903.1 - 8.9e-56 188.5 0.1 1.2e-55 188.1 0.1 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Ecl1 PF12855.2 EGO23904.1 - 1.3e-05 24.3 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor Ank PF00023.25 EGO23906.1 - 9.8e-06 25.1 0.0 0.003 17.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGO23906.1 - 3.4e-05 24.0 0.0 5.4e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO23906.1 - 6.6e-05 22.7 0.0 0.022 14.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGO23906.1 - 0.0018 18.4 0.0 0.0097 16.1 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO23906.1 - 0.025 15.1 0.0 0.038 14.5 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) FKBP_C PF00254.23 EGO23908.1 - 4.4e-31 106.7 0.0 5e-31 106.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3139 PF11337.3 EGO23909.1 - 1.1 9.6 3.2 2.3 8.5 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) CECR6_TMEM121 PF14997.1 EGO23910.1 - 0.084 12.4 0.0 0.089 12.3 0.0 1.0 1 0 0 1 1 1 0 CECR6/TMEM121 family Glycolytic PF00274.14 EGO23912.1 - 3.6e-76 255.8 0.0 4.8e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Aldo_ket_red PF00248.16 EGO23913.1 - 1.9e-64 217.2 0.2 2.2e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF45 PF01863.12 EGO23913.1 - 0.01 15.6 0.2 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 Kelch_4 PF13418.1 EGO23915.1 - 4.4e-20 71.1 4.0 1.2e-05 24.9 0.1 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EGO23915.1 - 1.8e-17 62.6 2.0 0.00013 21.9 0.0 5.3 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EGO23915.1 - 5.6e-17 61.2 2.2 0.00021 21.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 EGO23915.1 - 3.4e-16 58.5 0.2 0.00024 20.5 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EGO23915.1 - 2e-13 49.5 0.6 0.0024 17.5 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EGO23915.1 - 6e-13 48.5 4.4 5.2e-06 26.4 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain HSP70 PF00012.15 EGO23915.1 - 0.58 7.9 4.6 0.83 7.4 3.2 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-C3HC4_2 PF13923.1 EGO23916.1 - 0.00022 21.1 18.8 0.00022 21.1 13.1 3.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO23916.1 - 0.0011 18.7 17.4 0.0011 18.7 12.0 3.2 3 1 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.1 EGO23916.1 - 0.0068 16.1 9.7 0.0068 16.1 6.8 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EGO23916.1 - 0.17 11.6 29.0 0.027 14.2 11.3 3.0 3 0 0 3 3 3 0 zinc-RING finger domain zf-rbx1 PF12678.2 EGO23916.1 - 4.3 7.5 14.6 0.44 10.6 5.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO23916.1 - 6 6.6 35.6 0.021 14.5 10.0 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 EGO23919.1 - 9.5e-05 22.4 14.9 0.0015 18.7 0.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO23919.1 - 0.00026 21.1 8.5 0.0022 18.2 0.1 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO23919.1 - 0.85 10.0 0.1 0.85 10.0 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger double domain IGR PF09597.5 EGO23920.1 - 1e-16 60.5 0.0 1.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif Lipoprotein_20 PF13942.1 EGO23920.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Mon1 PF03164.9 EGO23921.1 - 3.7e-96 322.2 0.0 1.5e-58 198.4 0.2 1.9 2 0 0 2 2 2 2 Trafficking protein Mon1 BTB PF00651.26 EGO23922.1 - 6.7e-07 29.2 0.1 1.6e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain UPF0172 PF03665.8 EGO23923.1 - 5.2e-47 159.8 0.0 6.5e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Cellulase PF00150.13 EGO23925.1 - 3.1e-17 62.6 1.1 5.9e-17 61.7 0.8 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EBP PF05241.7 EGO23926.1 - 4.4e-65 218.3 4.2 5.6e-65 218.0 2.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein 7tm_4 PF13853.1 EGO23926.1 - 0.063 13.0 0.4 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Olfactory receptor DUF2781 PF10914.3 EGO23926.1 - 0.07 12.9 2.4 0.13 12.0 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF3302 PF11742.3 EGO23926.1 - 1.9 8.3 7.6 7.5 6.4 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) GPI-anchored PF10342.4 EGO23927.1 - 3.1e-07 30.7 0.1 4.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGO23927.1 - 0.0052 16.2 0.0 0.0062 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Nucleopor_Nup85 PF07575.8 EGO23929.1 - 0.14 10.3 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin YebF PF13995.1 EGO23932.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 YebF-like protein GPI-anchored PF10342.4 EGO23933.1 - 6.7e-07 29.6 0.0 8.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGO23933.1 - 0.086 12.3 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3761 PF12587.3 EGO23934.1 - 0.028 14.5 0.1 0.038 14.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3761) DUF2890 PF11081.3 EGO23934.1 - 0.086 12.8 7.0 0.098 12.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIE-A_C-term PF11521.3 EGO23934.1 - 0.15 12.0 8.5 0.19 11.6 5.9 1.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha BSP_II PF05432.6 EGO23934.1 - 0.22 10.7 3.5 0.23 10.7 2.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) eIF3_subunit PF08597.5 EGO23934.1 - 1.4 8.3 10.1 1.5 8.3 7.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SDA1 PF05285.7 EGO23934.1 - 4.3 6.5 10.7 4.9 6.3 7.4 1.0 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 EGO23934.1 - 6 6.3 10.1 7.9 5.9 7.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EGO23934.1 - 6.1 7.0 7.8 10 6.3 5.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Tcp11 PF05794.8 EGO23935.1 - 2.9e-49 167.9 0.0 1.3e-35 122.9 0.0 3.5 3 1 0 3 3 3 3 T-complex protein 11 ATP-synt_ab PF00006.20 EGO23937.1 - 1.4e-61 207.7 0.0 1.9e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO23937.1 - 4e-16 59.4 0.0 8e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO23937.1 - 2e-11 43.9 0.7 3.7e-11 43.0 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGO23937.1 - 0.00067 19.5 0.3 0.0015 18.3 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain TFCD_C PF12612.3 EGO23938.1 - 1.6e-36 125.5 0.3 3.8e-35 121.0 0.0 3.1 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EGO23938.1 - 2.4e-07 30.2 12.6 0.026 14.5 0.1 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EGO23938.1 - 3.4e-07 30.4 4.7 0.29 11.4 0.0 5.5 4 1 0 4 4 4 2 HEAT repeats Adaptin_N PF01602.15 EGO23938.1 - 0.00066 18.1 1.0 0.43 8.8 0.0 4.4 5 1 1 6 6 6 1 Adaptin N terminal region Cnd1 PF12717.2 EGO23938.1 - 0.0031 17.3 0.0 0.35 10.6 0.0 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EGO23938.1 - 0.026 15.0 13.7 1.5 9.3 0.0 6.0 6 0 0 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGO23938.1 - 0.029 14.7 0.0 2.1 8.8 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.4 EGO23938.1 - 0.16 10.2 4.6 6.4 4.9 0.1 3.5 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit BUD22 PF09073.5 EGO23939.1 - 7e-58 196.7 22.1 8.6e-58 196.4 15.3 1.1 1 0 0 1 1 1 1 BUD22 PP2C PF00481.16 EGO23941.1 - 1.7e-76 257.0 0.0 2.8e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C CHAT PF12770.2 EGO23943.1 - 9.6e-33 113.5 0.0 1.9e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EGO23943.1 - 1.1e-28 98.5 9.0 0.00038 20.0 0.1 11.5 4 2 5 12 12 12 8 TPR repeat TPR_12 PF13424.1 EGO23943.1 - 6.5e-21 74.0 11.4 0.035 14.0 0.0 12.2 6 3 7 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.23 EGO23943.1 - 4e-09 35.6 12.9 0.3 10.7 0.0 11.9 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO23943.1 - 2.1e-06 27.1 8.5 1.2 9.2 0.0 9.9 11 1 1 12 12 12 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO23943.1 - 1.3e-05 25.6 1.4 24 5.7 0.0 8.0 7 1 2 9 9 9 0 Tetratricopeptide repeat Sel1 PF08238.7 EGO23943.1 - 2.2e-05 24.9 0.0 6.6 7.5 0.0 5.9 7 0 0 7 7 6 1 Sel1 repeat TPR_14 PF13428.1 EGO23943.1 - 2.9e-05 24.3 6.0 3 8.7 0.0 9.5 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO23943.1 - 0.00022 21.1 8.5 6.6 7.2 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO23943.1 - 0.00023 20.7 0.3 3.7 7.5 0.0 6.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO23943.1 - 0.0093 16.2 2.7 27 5.1 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat Hex_IIIa PF02455.11 EGO23944.1 - 0.5 9.0 3.5 0.57 8.7 2.4 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Glyco_hydro_71 PF03659.9 EGO23946.1 - 1.2e-99 333.3 7.2 1.5e-99 333.0 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HA2 PF04408.18 EGO23947.1 - 5.4e-22 77.7 0.0 1.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO23947.1 - 2.3e-19 69.3 0.0 5.8e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO23947.1 - 6.8e-13 48.2 0.0 2.8e-12 46.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO23947.1 - 2.3e-06 27.2 0.0 6.7e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO23947.1 - 5.9e-05 23.2 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGO23947.1 - 0.041 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 EGO23947.1 - 0.052 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 EGO23947.1 - 0.084 12.6 2.2 0.44 10.3 0.0 2.9 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit SEN1_N PF12726.2 EGO23948.1 - 1e-136 456.9 0.0 1.8e-136 456.1 0.0 1.4 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EGO23948.1 - 1.1e-67 228.0 1.0 2e-67 227.2 0.7 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EGO23948.1 - 1.1e-58 197.8 0.0 2.4e-58 196.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO23948.1 - 2e-11 43.4 0.5 5.3e-11 42.1 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO23948.1 - 2.2e-07 30.6 0.7 0.001 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGO23948.1 - 4.5e-05 23.0 0.4 0.44 10.0 0.1 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EGO23948.1 - 0.0048 16.6 0.0 0.027 14.1 0.0 2.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGO23948.1 - 0.006 16.7 2.6 0.34 11.0 0.5 4.1 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EGO23948.1 - 0.01 15.2 0.2 0.033 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EGO23948.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 EGO23948.1 - 0.14 12.3 0.8 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Translin PF01997.11 EGO23949.1 - 1.4e-45 155.3 0.0 1.6e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1664 PF07889.7 EGO23949.1 - 0.011 15.5 0.8 0.047 13.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tail_P2_I PF09684.5 EGO23949.1 - 0.062 12.8 0.1 0.32 10.5 0.0 2.1 3 0 0 3 3 3 0 Phage tail protein (Tail_P2_I) DUF1325 PF07039.6 EGO23950.1 - 1.2e-33 115.4 0.0 1.6e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain HSP20 PF00011.16 EGO23951.1 - 1.2e-15 57.2 0.1 1e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family TIG PF01833.19 EGO23951.1 - 0.096 12.6 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 IPT/TIG domain CBFD_NFYB_HMF PF00808.18 EGO23952.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO23952.1 - 0.011 15.8 0.1 0.026 14.6 0.1 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGO23952.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated DIOX_N PF14226.1 EGO23954.1 - 2.3e-25 89.3 0.0 3.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO23954.1 - 2.3e-12 47.0 0.0 4.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA_bind PF01588.15 EGO23955.1 - 1.4e-29 101.7 0.0 2.4e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGO23955.1 - 3.9e-05 24.0 0.1 0.00012 22.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO23955.1 - 0.00043 20.2 1.6 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RNase_H2-Ydr279 PF09468.5 EGO23955.1 - 0.0022 17.2 2.8 0.003 16.7 2.0 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GST_C_2 PF13410.1 EGO23955.1 - 0.012 15.4 0.1 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NARP1 PF12569.3 EGO23955.1 - 0.073 11.8 9.4 0.1 11.3 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med19 PF10278.4 EGO23955.1 - 0.19 11.3 9.9 0.29 10.8 6.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Totivirus_coat PF05518.6 EGO23955.1 - 0.36 8.6 2.8 0.49 8.1 1.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein RR_TM4-6 PF06459.7 EGO23955.1 - 2 8.2 10.0 2.9 7.7 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EGO23955.1 - 2.5 7.4 11.0 3.7 6.8 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AA_permease_2 PF13520.1 EGO23956.1 - 1.2e-56 192.0 54.1 1.5e-56 191.7 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO23956.1 - 3.8e-18 65.1 51.1 1.2e-17 63.4 35.5 1.6 1 1 0 1 1 1 1 Amino acid permease Ribosomal_L6 PF00347.18 EGO23957.1 - 3.2e-27 94.8 0.0 2.1e-14 53.7 0.0 2.4 2 1 0 2 2 2 2 Ribosomal protein L6 ATP-synt_C PF00137.16 EGO23958.1 - 1.2e-26 92.4 30.5 1.4e-16 60.1 5.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C zf-CCHC_3 PF13917.1 EGO23959.1 - 1.3e-19 69.6 0.7 2.4e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO23959.1 - 0.0051 16.6 0.5 0.0084 15.9 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGO23959.1 - 0.037 13.5 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PEMT PF04191.8 EGO23961.1 - 9.6e-07 28.8 1.5 1.4e-06 28.3 0.3 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EGO23961.1 - 9.6e-05 22.5 0.6 9.6e-05 22.5 0.4 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EGO23961.1 - 0.0069 15.7 0.6 0.065 12.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) DUF2637 PF10935.3 EGO23961.1 - 0.54 10.2 4.6 2.8 7.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2637) DUF837 PF05769.6 EGO23962.1 - 0.00017 21.1 7.3 0.003 17.1 1.5 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF837) Nsp1_C PF05064.8 EGO23962.1 - 0.0048 16.5 2.4 0.006 16.2 0.5 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region ART PF01129.13 EGO23962.1 - 0.034 13.2 0.5 0.05 12.6 0.4 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase bZIP_1 PF00170.16 EGO23962.1 - 0.17 11.8 8.4 0.1 12.6 1.6 2.8 2 1 0 2 2 2 0 bZIP transcription factor NYD-SP28_assoc PF14775.1 EGO23962.1 - 0.17 11.5 9.3 1.5 8.5 1.1 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF2959 PF11172.3 EGO23962.1 - 0.19 11.4 6.9 0.25 11.0 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) IFT20 PF14931.1 EGO23962.1 - 0.2 11.5 5.7 2.3 8.1 0.5 2.7 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DivIVA PF05103.8 EGO23962.1 - 0.33 11.0 6.7 0.29 11.1 2.1 2.3 1 1 1 2 2 2 0 DivIVA protein bZIP_2 PF07716.10 EGO23962.1 - 0.4 10.5 5.5 8.8 6.2 0.4 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF4446 PF14584.1 EGO23962.1 - 0.43 10.4 4.7 2.5 7.8 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF3552 PF12072.3 EGO23962.1 - 1.6 7.8 9.1 0.46 9.6 2.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) OmpH PF03938.9 EGO23962.1 - 9 6.2 8.6 19 5.1 5.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PHD PF00628.24 EGO23965.1 - 1.1e-06 28.2 5.4 2.3e-06 27.1 3.8 1.6 1 1 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EGO23965.1 - 0.0021 17.3 2.8 0.0034 16.6 1.9 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EGO23965.1 - 0.014 15.1 2.2 0.014 15.1 1.5 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EGO23965.1 - 0.18 11.1 10.4 1.6 8.1 0.3 3.2 3 0 0 3 3 3 0 PHD-finger F-actin_cap_A PF01267.12 EGO23966.1 - 6.9e-92 307.3 0.0 7.8e-92 307.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ICL PF00463.16 EGO23967.1 - 6.9e-246 816.5 0.1 7.8e-246 816.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGO23967.1 - 2.1e-10 40.2 0.0 3.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PT-TG PF14449.1 EGO23967.1 - 0.043 13.5 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Pre-toxin TG Arg_repressor_C PF02863.13 EGO23967.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Glycos_transf_4 PF00953.16 EGO23968.1 - 5.7e-30 104.2 7.3 5.7e-30 104.2 5.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 DKNYY PF13644.1 EGO23969.1 - 0.04 14.1 1.0 0.045 14.0 0.7 1.1 1 0 0 1 1 1 0 DKNYY family RNA_pol_Rpb8 PF03870.10 EGO23969.1 - 0.092 12.9 0.2 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb8 zf-CCHC PF00098.18 EGO23970.1 - 0.00049 19.8 4.2 0.0008 19.2 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EGO23970.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-PHD-like PF15446.1 EGO23970.1 - 0.034 13.4 3.0 0.048 12.9 2.1 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain HTH_23 PF13384.1 EGO23972.1 - 4.2e-05 23.0 0.9 0.33 10.6 0.0 3.2 3 0 0 3 3 3 2 Homeodomain-like domain HTH_38 PF13936.1 EGO23972.1 - 0.0062 16.0 0.1 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.14 EGO23972.1 - 0.091 12.0 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Myb_DNA-bind_3 PF12776.2 EGO23973.1 - 0.00012 22.6 0.2 0.00026 21.5 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO23973.1 - 0.0051 16.9 0.4 0.019 15.0 0.3 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain NPCBM PF08305.6 EGO23973.1 - 0.051 13.5 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 NPCBM/NEW2 domain Calpain_inhib PF00748.14 EGO23973.1 - 0.27 11.5 4.0 0.78 10.0 2.8 1.7 2 0 0 2 2 2 0 Calpain inhibitor dCMP_cyt_deam_1 PF00383.17 EGO23974.1 - 2e-07 30.5 0.0 4.3e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGO23974.1 - 0.03 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Malic_M PF03949.10 EGO23975.1 - 2.9e-85 285.8 0.0 3.8e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGO23975.1 - 2.6e-65 219.4 0.0 4.4e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MRP-L20 PF12824.2 EGO23976.1 - 5.7e-29 101.1 6.6 8.9e-29 100.5 4.6 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Hemerythrin PF01814.18 EGO23978.1 - 3e-14 53.3 3.3 4.5e-14 52.7 2.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Spc7 PF08317.6 EGO23978.1 - 0.067 11.8 0.8 0.096 11.3 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GST_C_2 PF13410.1 EGO23979.1 - 5.9e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO23979.1 - 2.3e-11 43.7 0.0 3.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO23979.1 - 8.1e-11 41.9 0.0 1.9e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO23979.1 - 3.1e-10 39.8 0.0 6.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO23979.1 - 2.8e-08 33.6 0.0 5.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO23979.1 - 0.0002 21.7 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KAT11 PF08214.6 EGO23980.1 - 4e-14 52.4 0.0 5.3e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cullin PF00888.17 EGO23981.1 - 9.3e-190 632.0 18.2 1.2e-189 631.7 12.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGO23981.1 - 5.3e-16 58.2 1.9 2.2e-15 56.2 1.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.5 EGO23981.1 - 0.014 15.0 0.1 0.07 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) GntR PF00392.16 EGO23981.1 - 0.016 14.6 0.2 0.036 13.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ubie_methyltran PF01209.13 EGO23982.1 - 7.7e-77 257.5 0.0 9.6e-77 257.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO23982.1 - 2.4e-12 46.7 0.0 3.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO23982.1 - 9.1e-10 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO23982.1 - 2.3e-09 37.6 0.0 3.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO23982.1 - 3.7e-09 36.8 0.0 6.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO23982.1 - 8e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO23982.1 - 3.4e-05 24.4 0.0 6.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO23982.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Cullin PF00888.17 EGO23984.1 - 7.7e-39 133.7 0.2 2.8e-38 131.8 0.2 1.7 1 1 0 1 1 1 1 Cullin family Tmp39 PF10271.4 EGO23984.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein Cullin PF00888.17 EGO23985.1 - 1.7e-40 139.1 4.0 2.1e-40 138.8 2.8 1.0 1 0 0 1 1 1 1 Cullin family DUF4298 PF14131.1 EGO23985.1 - 0.035 13.9 3.3 0.52 10.2 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) BAR PF03114.13 EGO23985.1 - 0.038 13.5 0.2 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 BAR domain BRCT_assoc PF12820.2 EGO23985.1 - 0.046 13.4 0.1 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT DUF4484 PF14831.1 EGO23985.1 - 0.072 13.1 0.2 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Fcf2 PF08698.6 EGO23987.1 - 1e-19 70.3 0.3 1.2e-18 66.9 0.0 2.4 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing DUF4414 PF14377.1 EGO23987.1 - 0.016 15.1 0.3 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) RNF111_N PF15303.1 EGO23987.1 - 0.024 14.1 5.8 0.045 13.2 4.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus AurF PF11583.3 EGO23987.1 - 0.053 12.4 0.1 0.085 11.7 0.1 1.3 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF SHS2_FTSA PF02491.15 EGO23987.1 - 0.083 12.7 0.2 0.58 10.0 0.3 2.2 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA Fes1 PF08609.5 EGO23987.1 - 0.21 12.1 1.3 0.47 10.9 0.9 1.5 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 FlaG PF03646.10 EGO23987.1 - 0.3 11.2 3.6 0.62 10.2 2.5 1.4 1 0 0 1 1 1 0 FlaG protein SR-25 PF10500.4 EGO23987.1 - 4.2 6.7 13.1 0.11 11.9 4.5 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fungal_trans PF04082.13 EGO23988.1 - 3e-08 32.8 0.3 2e-07 30.1 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO23988.1 - 2e-05 24.3 5.7 3.3e-05 23.6 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EGO23989.1 - 1.1e-15 58.0 0.0 2.4e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EGO23989.1 - 3.5e-09 36.2 0.0 1.7e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EGO23989.1 - 3.5e-09 35.9 0.1 8.1e-07 28.2 0.1 3.1 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGO23989.1 - 9.5e-07 27.7 0.0 2.3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO23989.1 - 2.4e-06 27.1 0.4 0.00018 21.0 0.4 3.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO23989.1 - 6.9e-06 25.1 0.5 0.01 14.7 0.1 2.5 1 1 1 2 2 2 2 Male sterility protein DUF2462 PF09495.5 EGO23990.1 - 2.7e-17 63.2 12.0 3.2e-17 63.0 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) AOX PF01786.12 EGO23991.1 - 8.1e-87 289.9 0.0 9.8e-87 289.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase PH_4 PF15404.1 EGO23992.1 - 1.9e-27 96.0 1.5 2.4e-24 85.8 0.6 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain zf-Nse PF11789.3 EGO23993.1 - 3.3e-16 58.5 0.1 5.9e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGO23993.1 - 2.5e-05 23.9 0.4 5.5e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 EGO23993.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 EGO23993.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGO23993.1 - 0.013 15.5 0.3 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO23993.1 - 0.013 15.2 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RAG1 PF10426.4 EGO23993.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.20 EGO23993.1 - 0.021 14.4 0.1 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosom_S12_S23 PF00164.20 EGO23994.1 - 1.1e-46 157.2 2.7 1.2e-46 157.0 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MRP-L47 PF06984.8 EGO23996.1 - 6.3e-21 74.0 0.1 1e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 EGO23996.1 - 0.00043 19.8 0.3 0.0017 17.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Complex1_LYR PF05347.10 EGO23997.1 - 1.1e-09 37.9 0.8 1.7e-09 37.3 0.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO23997.1 - 2.5e-08 33.9 0.7 3.6e-08 33.4 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like SQS_PSY PF00494.14 EGO23998.1 - 1.3e-44 152.5 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PBP1_TM PF14812.1 EGO23999.1 - 0.42 10.9 11.5 0.47 10.7 0.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTP PF05232.7 EGO24000.1 - 7.8 6.3 6.6 0.98 9.2 1.4 1.9 1 1 1 2 2 2 0 Bacterial Transmembrane Pair family vATP-synt_AC39 PF01992.11 EGO24001.1 - 9.8e-98 327.3 0.0 1.1e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CRAL_TRIO PF00650.15 EGO24002.1 - 6.5e-28 97.2 0.0 1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO24002.1 - 8.5e-10 38.6 0.1 2.7e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PepSY_TM_1 PF13172.1 EGO24003.1 - 4.7 7.0 7.3 0.85 9.4 1.8 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO24004.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO24004.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO24004.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_6 PF12697.2 EGO24005.1 - 4.6e-26 92.1 0.0 5.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24005.1 - 4.1e-11 42.8 0.0 7.2e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO24005.1 - 3.2e-09 36.6 0.0 1.8e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGO24005.1 - 4.7e-05 23.1 0.0 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EGO24005.1 - 0.0059 16.0 0.0 2.5 7.5 0.0 3.0 3 0 0 3 3 3 1 Serine hydrolase (FSH1) Peptidase_S10 PF00450.17 EGO24005.1 - 0.032 13.4 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Serine carboxypeptidase Peptidase_S9 PF00326.16 EGO24005.1 - 0.047 12.9 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGO24006.1 - 3.2e-26 92.6 0.0 3.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO24006.1 - 5.6e-11 42.4 0.1 1.5e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO24006.1 - 3.2e-10 39.9 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO24006.1 - 9.1e-05 22.2 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EGO24006.1 - 0.013 15.0 0.0 0.06 12.7 0.0 2.0 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.2 EGO24006.1 - 0.072 11.9 0.0 0.21 10.4 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.8 EGO24006.1 - 0.079 12.5 0.0 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_6 PF12697.2 EGO24008.1 - 4e-20 72.6 0.1 6.1e-20 72.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO24008.1 - 3.7e-07 29.9 0.3 1.2e-06 28.2 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO24008.1 - 4.1e-05 23.3 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO24008.1 - 0.03 14.1 0.1 0.22 11.3 0.1 2.2 1 1 0 1 1 1 0 Putative lysophospholipase SR-25 PF10500.4 EGO24009.1 - 0.044 13.2 10.9 0.047 13.1 7.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.10 EGO24009.1 - 0.4 11.2 5.1 0.52 10.8 3.5 1.2 1 0 0 1 1 1 0 Chorion family 2 Ndc1_Nup PF09531.5 EGO24009.1 - 0.59 8.4 2.7 0.53 8.6 1.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3827 PF12877.2 EGO24009.1 - 1.5 6.7 6.3 1.5 6.7 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.4 EGO24009.1 - 2.7 6.1 7.3 2.7 6.1 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Ustilago_mating PF05722.7 EGO24009.1 - 2.8 7.1 9.1 3.3 6.9 6.3 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein E1_dh PF00676.15 EGO24011.1 - 8.9e-87 290.5 0.0 1.1e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Spuma_A9PTase PF03539.9 EGO24011.1 - 0.14 12.0 0.6 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) SMC_N PF02463.14 EGO24012.1 - 1.1e-16 60.7 14.7 4.8e-16 58.6 10.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO24012.1 - 3.4e-11 43.8 20.0 3.4e-11 43.8 13.9 5.0 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 EGO24012.1 - 9.6e-06 25.7 0.3 0.0018 18.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO24012.1 - 0.00018 20.9 0.0 0.00051 19.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGO24012.1 - 0.014 15.2 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FlaC_arch PF05377.6 EGO24012.1 - 1.2 9.1 5.7 3.2 7.7 0.7 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_15 PF13175.1 EGO24012.1 - 1.7 7.6 20.2 0.005 15.9 4.0 3.4 2 2 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGO24012.1 - 7.1 6.6 7.2 9.2 6.2 0.1 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase Peptidase_C48 PF02902.14 EGO24014.1 - 2e-14 53.7 0.1 8.5e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Mur_ligase_M PF08245.7 EGO24015.1 - 4.7e-05 23.5 0.0 0.00015 21.8 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain SKN1 PF03935.10 EGO24019.1 - 1.7e-194 646.6 3.7 2e-194 646.4 2.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ThiF PF00899.16 EGO24020.1 - 1.4e-16 60.5 0.2 2.6e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family DUF2924 PF11149.3 EGO24020.1 - 0.14 12.2 0.1 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Fungal_trans PF04082.13 EGO24021.1 - 5e-22 78.0 0.0 8.5e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO24021.1 - 6.7e-08 32.3 10.6 1.3e-07 31.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.1 EGO24022.1 - 0.00018 21.4 0.0 0.017 15.0 0.0 3.4 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.15 EGO24022.1 - 0.0031 17.3 0.1 51 4.1 0.0 5.1 4 0 0 4 4 4 0 PPR repeat Ank_2 PF12796.2 EGO24022.1 - 0.0086 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF4072 PF13284.1 EGO24022.1 - 0.042 14.0 0.5 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) Ank PF00023.25 EGO24022.1 - 0.066 13.0 0.0 23 5.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat gag_pre-integrs PF13976.1 EGO24025.1 - 1.4e-05 24.6 0.2 1.4e-05 24.6 0.1 1.5 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 EGO24025.1 - 0.0022 18.0 0.0 0.0062 16.6 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain IBR PF01485.16 EGO24026.1 - 2e-13 49.9 46.2 8.1e-07 28.8 2.9 4.4 4 0 0 4 4 4 4 IBR domain zf-C3HC4 PF00097.20 EGO24026.1 - 0.00046 19.7 6.7 0.00046 19.7 4.7 4.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO24026.1 - 0.01 15.6 6.2 0.01 15.6 4.3 5.0 3 2 1 4 4 4 0 Ring finger domain GRASP55_65 PF04495.9 EGO24027.1 - 4.1e-62 208.2 0.0 4.4e-45 153.0 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EGO24027.1 - 0.00075 19.3 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain BTB PF00651.26 EGO24028.1 - 0.00011 22.1 0.1 0.59 10.1 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain RRM_1 PF00076.17 EGO24029.1 - 4.3e-51 170.4 1.0 2.8e-18 65.3 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO24029.1 - 4e-42 142.0 0.4 5.3e-14 51.9 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO24029.1 - 1.5e-22 79.1 1.6 1.2e-07 31.4 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EGO24029.1 - 1.7e-06 27.9 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Nup35_RRM_2 PF14605.1 EGO24029.1 - 0.00025 20.7 0.0 0.12 12.1 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_16 PF13432.1 EGO24029.1 - 0.042 14.5 4.2 0.2 12.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Nup35_RRM PF05172.8 EGO24029.1 - 0.067 12.9 0.0 1.7 8.4 0.0 2.7 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif adh_short PF00106.20 EGO24031.1 - 2.5e-19 69.8 0.8 5.5e-14 52.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EGO24031.1 - 1.7e-15 57.4 1.8 6.9e-14 52.1 1.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO24031.1 - 1.9e-06 27.6 0.2 4.1e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EGO24031.1 - 0.006 16.6 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EGO24031.1 - 0.011 16.1 0.3 0.033 14.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGO24031.1 - 0.053 13.1 0.4 0.093 12.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGO24032.1 - 1.5e-47 162.3 0.9 8.2e-41 140.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO24032.1 - 4.7e-09 35.6 4.3 1.6e-08 33.8 3.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGO24032.1 - 2.8e-08 33.2 0.3 4.6e-05 22.6 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EGO24032.1 - 4.2e-05 22.5 7.4 0.00013 20.9 0.6 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EGO24032.1 - 6.5e-05 22.9 0.1 0.071 12.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO24032.1 - 0.00022 19.8 1.2 0.07 11.5 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 EGO24032.1 - 0.0012 18.7 0.5 0.0081 16.1 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO24032.1 - 0.0029 17.6 0.1 0.086 12.8 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO24032.1 - 0.011 14.6 0.1 0.07 12.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 EGO24032.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 EGO24032.1 - 0.11 12.5 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PX PF00787.19 EGO24033.1 - 4.6e-14 52.1 1.0 9.7e-11 41.4 0.2 3.0 2 0 0 2 2 2 2 PX domain PLDc_2 PF13091.1 EGO24033.1 - 2.7e-13 49.7 0.0 3.4e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGO24033.1 - 4.3e-13 48.6 0.9 3.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PH PF00169.24 EGO24033.1 - 0.00046 20.3 0.1 0.0013 18.8 0.1 1.8 1 0 0 1 1 1 1 PH domain RE_NgoFVII PF09565.5 EGO24033.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 NgoFVII restriction endonuclease PROCN PF08083.6 EGO24035.1 - 1.6e-219 728.4 7.5 6.1e-219 726.4 4.7 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGO24035.1 - 2.9e-126 419.4 0.3 5.2e-126 418.6 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGO24035.1 - 2e-92 306.8 1.2 5.6e-92 305.3 0.8 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGO24035.1 - 6.5e-80 266.1 2.1 6.5e-80 266.1 1.5 2.4 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EGO24035.1 - 8.8e-69 229.3 0.1 1.6e-68 228.4 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EGO24035.1 - 2.5e-43 145.8 0.1 5.7e-43 144.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EGO24035.1 - 6.5e-35 119.5 0.0 1.9e-34 118.0 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain JAB PF01398.16 EGO24035.1 - 0.00028 20.6 0.0 0.00075 19.2 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TMEM206 PF15122.1 EGO24038.1 - 0.0049 15.8 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 TMEM206 protein family Zip PF02535.17 EGO24042.1 - 0.26 10.2 5.2 0.35 9.8 3.4 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EGO24042.1 - 1.5 6.4 5.8 1.5 6.3 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rhodanese PF00581.15 EGO24043.1 - 1.3e-10 41.6 0.0 1.6e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain But2 PF09792.4 EGO24044.1 - 0.00022 21.0 0.4 0.00038 20.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Porin_3 PF01459.17 EGO24047.1 - 2e-66 224.0 4.2 2.3e-66 223.9 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Cofilin_ADF PF00241.15 EGO24048.1 - 4.7e-42 142.8 0.1 5.2e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CH PF00307.26 EGO24049.1 - 5.6e-42 142.1 0.0 6.7e-23 80.7 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EGO24049.1 - 2.8e-15 56.0 0.0 9.2e-15 54.3 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EGO24049.1 - 2.2e-11 43.2 0.1 5.3e-08 32.4 0.1 3.0 2 1 1 3 3 3 2 CAMSAP CH domain EF-hand_8 PF13833.1 EGO24049.1 - 0.0017 17.9 0.0 1.1 8.8 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain pair Spectrin PF00435.16 EGO24049.1 - 0.0038 17.4 0.7 0.93 9.8 0.1 2.7 2 1 0 2 2 2 1 Spectrin repeat EF-hand_6 PF13405.1 EGO24049.1 - 0.01 15.6 0.0 0.16 11.9 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain Herpes_UL17 PF04559.7 EGO24049.1 - 0.012 14.1 0.4 0.019 13.6 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein Syntaxin PF00804.20 EGO24049.1 - 0.055 13.6 0.3 0.055 13.6 0.2 3.1 2 1 0 2 2 2 0 Syntaxin EF-hand_7 PF13499.1 EGO24049.1 - 0.18 11.9 1.1 1.7 8.8 0.2 2.8 2 1 0 2 2 2 0 EF-hand domain pair Baculo_PEP_C PF04513.7 EGO24049.1 - 0.29 10.9 5.6 0.085 12.6 0.5 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SSrecog PF03531.9 EGO24050.1 - 2.4e-76 255.9 0.1 5.6e-76 254.7 0.0 1.6 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGO24050.1 - 5.6e-25 87.1 0.0 3e-22 78.4 0.0 2.5 2 0 0 2 2 2 2 Histone chaperone Rttp106-like Nup160 PF11715.3 EGO24052.1 - 0.00044 18.5 0.0 0.0008 17.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 EGO24052.1 - 0.021 14.6 0.7 31 4.6 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat MIP PF00230.15 EGO24055.1 - 7.3e-50 169.5 5.0 9.1e-50 169.2 3.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.15 EGO24055.1 - 0.012 15.6 0.7 0.012 15.6 0.5 2.1 2 0 0 2 2 2 0 EamA-like transporter family PAP2 PF01569.16 EGO24055.1 - 1 9.0 5.4 0.84 9.3 1.7 2.3 1 1 1 2 2 2 0 PAP2 superfamily NTR2 PF15458.1 EGO24056.1 - 1.3e-62 211.3 6.7 1.3e-62 211.3 4.7 1.6 2 0 0 2 2 2 1 Nineteen complex-related protein 2 Snapin_Pallidin PF14712.1 EGO24056.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Snapin/Pallidin GCFC PF07842.7 EGO24056.1 - 0.11 11.8 0.0 0.51 9.6 0.0 2.0 1 1 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein SPT6_acidic PF14632.1 EGO24057.1 - 0.0003 20.8 7.6 0.0012 18.9 5.3 1.8 1 1 0 1 1 1 1 Acidic N-terminal SPT6 mRNA_triPase PF02940.10 EGO24058.1 - 7.3e-52 176.2 0.0 8.7e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Zip PF02535.17 EGO24059.1 - 3.5e-31 108.4 7.8 5.7e-31 107.6 5.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter OCIA PF07051.6 EGO24059.1 - 0.082 12.3 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF3353 PF11833.3 EGO24059.1 - 8 5.8 7.2 12 5.3 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) PhyH PF05721.8 EGO24060.1 - 8.7e-05 22.6 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.8 EGO24061.1 - 0.00024 21.2 0.0 0.78 9.7 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Anthrax-tox_M PF09156.5 EGO24061.1 - 0.07 12.2 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain PhyH PF05721.8 EGO24062.1 - 0.0073 16.3 0.0 0.31 11.0 0.0 2.3 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF390 PF04094.9 EGO24063.1 - 2.2 6.2 6.7 2.5 6.0 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Mit_KHE1 PF10173.4 EGO24064.1 - 2.1e-50 171.1 0.1 3.9e-50 170.3 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GFO_IDH_MocA PF01408.17 EGO24065.1 - 3.1e-27 95.4 0.0 5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO24065.1 - 4.4e-06 26.4 0.0 9.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EGO24065.1 - 0.008 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGO24065.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lipase_3 PF01764.20 EGO24066.1 - 1.9e-23 82.6 0.0 2.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO24066.1 - 0.00019 21.1 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO24066.1 - 0.00025 20.9 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24066.1 - 0.0025 17.5 0.1 0.0052 16.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EGO24066.1 - 0.0051 16.2 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) UPF0227 PF05728.7 EGO24066.1 - 0.0076 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EGO24066.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold IL13 PF03487.8 EGO24066.1 - 0.083 12.6 0.5 0.18 11.5 0.4 1.6 1 0 0 1 1 1 0 Interleukin-13 PepSY_TM_1 PF13172.1 EGO24067.1 - 5 6.9 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix DUF500 PF04366.7 EGO24069.1 - 9.2e-44 147.9 0.1 1.8e-43 146.9 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF500) Phosphodiest PF01663.17 EGO24070.1 - 1.1e-69 235.4 0.4 1.4e-69 235.1 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Prenyltransf PF01255.14 EGO24071.1 - 1.3e-77 259.8 0.0 1.6e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase LRR_6 PF13516.1 EGO24072.1 - 9.3e-12 43.7 10.2 0.16 12.0 0.1 7.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 EGO24072.1 - 4.4e-07 29.3 10.5 0.0094 15.5 0.1 5.3 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO24072.1 - 7.3e-07 28.3 0.9 5.5 7.4 0.2 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 EGO24072.1 - 0.00063 19.4 10.4 5.6 6.8 1.8 4.8 3 3 0 4 4 4 3 Leucine rich repeat DUF4230 PF14014.1 EGO24072.1 - 0.078 12.8 1.6 0.14 11.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) LRR_7 PF13504.1 EGO24072.1 - 2.1 8.9 4.9 70 4.3 0.0 4.5 5 0 0 5 5 5 0 Leucine rich repeat Flavoprotein PF02441.14 EGO24074.1 - 2.7e-43 146.7 0.1 3.4e-43 146.4 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Mob1_phocein PF03637.12 EGO24075.1 - 7.2e-66 221.1 0.6 9.1e-66 220.8 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Acyl-thio_N PF12590.3 EGO24077.1 - 0.019 15.3 1.7 0.021 15.2 0.5 1.5 1 1 1 2 2 2 0 Acyl-ATP thioesterase AKAP2_C PF15304.1 EGO24077.1 - 0.17 11.5 4.7 0.18 11.4 3.3 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Glyco_hydro_15 PF00723.16 EGO24079.1 - 8.3e-95 317.9 0.2 9.8e-95 317.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EGO24079.1 - 3.6e-29 100.1 3.6 7.9e-29 99.1 2.5 1.6 1 0 0 1 1 1 1 Starch binding domain Crust_neurohorm PF01147.12 EGO24080.1 - 0.0013 18.0 0.8 0.39 10.0 0.0 2.7 2 0 0 2 2 2 2 Crustacean CHH/MIH/GIH neurohormone family zf-RING_2 PF13639.1 EGO24081.1 - 9.7e-14 50.9 2.7 2.2e-13 49.7 1.9 1.7 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EGO24081.1 - 4.8e-12 45.4 0.0 9.1e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EGO24081.1 - 1.3e-05 25.1 2.2 1.3e-05 25.1 1.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO24081.1 - 1.3e-05 24.7 1.1 2.7e-05 23.7 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO24081.1 - 1.7e-05 24.7 2.7 4e-05 23.5 1.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO24081.1 - 5.5e-05 22.7 1.5 0.00012 21.6 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO24081.1 - 0.0001 21.9 1.3 0.00021 20.8 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EGO24081.1 - 0.028 13.9 1.1 0.062 12.8 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Corona_S2 PF01601.11 EGO24081.1 - 0.029 12.4 0.0 0.042 11.9 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-Apc11 PF12861.2 EGO24081.1 - 0.035 13.9 0.7 0.12 12.2 0.5 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGO24081.1 - 0.057 13.3 3.2 0.48 10.4 2.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain BatD PF13584.1 EGO24081.1 - 0.24 9.9 0.1 0.34 9.4 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance zf-CCCH PF00642.19 EGO24082.1 - 1.1e-19 69.6 31.2 3.9e-10 39.1 1.2 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO24082.1 - 0.037 14.0 30.0 0.073 13.0 3.3 3.8 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Heme_oxygenase PF01126.15 EGO24083.1 - 1.7e-27 96.3 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase zf-TFIIB PF13453.1 EGO24083.1 - 0.044 12.9 0.2 0.082 12.1 0.1 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Asp PF00026.18 EGO24084.1 - 1.1e-21 77.3 5.5 8.7e-19 67.9 3.8 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO24084.1 - 0.0008 19.8 1.1 0.005 17.3 0.4 2.6 2 1 0 2 2 2 1 Aspartyl protease Orthoreo_P10 PF07204.6 EGO24084.1 - 0.002 17.7 0.1 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Herpes_gE PF02480.11 EGO24084.1 - 0.027 12.7 0.0 0.039 12.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TAXi_N PF14543.1 EGO24084.1 - 0.031 14.2 1.1 0.78 9.6 0.8 2.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal TMEM52 PF14979.1 EGO24084.1 - 0.046 13.6 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Transmembrane 52 gag-asp_proteas PF13975.1 EGO24084.1 - 0.1 12.4 0.0 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 EGO24085.1 - 7.4e-22 77.9 0.1 1.1e-17 64.2 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO24085.1 - 5.5e-05 23.5 4.1 0.0012 19.2 0.5 3.4 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO24085.1 - 0.11 12.3 0.2 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease p450 PF00067.17 EGO24086.1 - 5.2e-72 242.8 0.0 5.8e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 EGO24090.1 - 2.2e-16 59.9 0.0 3e-14 53.0 0.0 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Shisa PF13908.1 EGO24090.1 - 0.0003 21.0 0.6 0.00052 20.2 0.3 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Asp_protease_2 PF13650.1 EGO24090.1 - 0.00063 20.1 1.5 0.0048 17.3 0.0 3.0 4 0 0 4 4 3 1 Aspartyl protease RCR PF12273.3 EGO24090.1 - 0.0031 18.0 0.1 0.0062 17.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 EGO24090.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 EGO24090.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Prominin PF05478.6 EGO24090.1 - 0.0092 13.5 0.4 0.013 13.0 0.3 1.1 1 0 0 1 1 1 1 Prominin DUF912 PF06024.7 EGO24090.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 EGO24090.1 - 0.056 11.7 0.1 0.079 11.2 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rhabdo_glycop PF00974.13 EGO24090.1 - 0.13 10.5 0.1 0.22 9.7 0.0 1.4 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein SCIMP PF15050.1 EGO24090.1 - 0.2 11.5 1.7 0.66 9.8 1.3 1.8 2 0 0 2 2 2 0 SCIMP protein Rifin_STEVOR PF02009.11 EGO24090.1 - 0.23 11.0 0.2 0.36 10.4 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Adeno_E3_CR2 PF02439.10 EGO24090.1 - 0.89 9.1 8.3 1.6 8.3 5.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HNH_2 PF13391.1 EGO24091.1 - 2.9e-06 26.9 0.6 8.4e-06 25.4 0.4 1.8 1 1 0 1 1 1 1 HNH endonuclease Dynactin_p62 PF05502.8 EGO24092.1 - 2.4e-89 300.3 3.2 1.3e-54 185.7 4.0 2.1 1 1 1 2 2 2 2 Dynactin p62 family Myb_DNA-bind_3 PF12776.2 EGO24095.1 - 0.00053 20.5 2.8 0.00086 19.8 2.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO24095.1 - 0.0016 18.5 2.0 0.0022 18.1 1.0 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EGO24095.1 - 0.004 17.0 1.1 0.004 17.0 0.8 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Protamine_3 PF08188.6 EGO24095.1 - 0.073 13.0 0.8 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 Spermatozal protamine family UBN2_3 PF14244.1 EGO24096.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO24096.1 - 1.4e-05 24.3 0.1 2.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EGO24096.1 - 4.3e-05 23.2 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO24096.1 - 0.00063 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 EGO24097.1 - 0.025 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO24097.1 - 0.092 12.4 0.9 0.88 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO24097.1 - 1.6 8.5 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein gag_pre-integrs PF13976.1 EGO24098.1 - 2.8e-11 42.8 0.3 3.8e-11 42.4 0.2 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain DDE_1 PF03184.14 EGO24099.1 - 4.6e-07 29.1 0.4 2.2e-06 26.9 0.3 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease SAP PF02037.22 EGO24099.1 - 0.016 14.7 0.9 0.044 13.3 0.0 2.1 2 0 0 2 2 2 0 SAP domain PIG-L PF02585.12 EGO24099.1 - 0.039 14.4 1.9 0.14 12.6 0.3 2.2 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase HTH_Tnp_Tc5 PF03221.11 EGO24100.1 - 0.057 13.2 0.0 0.81 9.5 0.0 2.5 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain USP8_interact PF08941.5 EGO24100.1 - 0.14 11.5 0.1 0.23 10.7 0.0 1.4 2 0 0 2 2 2 0 USP8 interacting But2 PF09792.4 EGO24103.1 - 3.8e-06 26.7 0.1 9.1e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 EGO24104.1 - 1e-25 90.7 0.4 2.9e-25 89.2 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2419 PF10343.4 EGO24107.1 - 6.9e-82 274.9 0.0 9.4e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) HHH_8 PF14716.1 EGO24108.1 - 7.6e-14 51.6 0.2 4.9e-11 42.6 0.1 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EGO24108.1 - 2.1e-09 36.7 0.0 4.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EGO24108.1 - 8.7e-07 29.0 0.0 8.7e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 EGO24108.1 - 9.6e-06 25.0 0.3 0.014 15.0 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif Cdd1 PF11731.3 EGO24108.1 - 0.0011 18.8 0.0 0.0081 16.0 0.0 2.0 2 0 0 2 2 2 1 Pathogenicity locus HHH_2 PF12826.2 EGO24108.1 - 0.011 15.5 0.0 5.2 7.0 0.0 2.5 2 1 1 3 3 3 0 Helix-hairpin-helix motif HRDC PF00570.18 EGO24108.1 - 0.055 13.1 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 HRDC domain SNF5 PF04855.7 EGO24109.1 - 1.6e-43 148.9 0.5 4.8e-43 147.3 0.3 1.7 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 LRRNT PF01462.13 EGO24109.1 - 0.044 13.2 0.0 5.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-H2C2_2 PF13465.1 EGO24110.1 - 0.0062 16.7 1.1 0.013 15.7 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGO24110.1 - 0.03 14.6 0.2 0.065 13.6 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO24110.1 - 0.11 12.9 0.9 0.18 12.2 0.1 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger Med25_VWA PF11265.3 EGO24111.1 - 0.25 10.3 2.1 0.21 10.5 0.5 1.5 1 1 1 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A DUF1517 PF07466.6 EGO24111.1 - 8.3 5.3 11.6 1.1 8.2 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Gelsolin PF00626.17 EGO24112.1 - 4.1e-34 116.1 0.0 3.2e-17 61.9 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat RdRP PF05183.7 EGO24112.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF295 PF03478.13 EGO24112.1 - 0.044 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Methyltransf_33 PF10017.4 EGO24113.1 - 1.2e-32 112.4 0.1 2.1e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EGO24113.1 - 1.2e-23 83.8 4.1 3.7e-13 49.4 0.1 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGO24113.1 - 4.2e-06 27.1 0.4 1e-05 25.9 0.3 1.6 1 0 0 1 1 1 1 DinB superfamily zf-DHHC PF01529.15 EGO24115.1 - 5.4e-37 126.8 0.0 5.4e-37 126.8 0.0 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase NAD_binding_10 PF13460.1 EGO24116.1 - 4.7e-14 52.7 0.0 7.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO24116.1 - 1.6e-09 37.5 0.0 2.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGO24116.1 - 4.7e-05 22.7 0.1 9.5e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EGO24116.1 - 0.00062 18.7 0.0 0.032 13.1 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain UDPG_MGDP_dh_N PF03721.9 EGO24116.1 - 0.001 18.5 0.4 0.0018 17.7 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EGO24116.1 - 0.0054 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 EGO24116.1 - 0.06 13.2 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EGO24116.1 - 0.076 11.7 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Asp PF00026.18 EGO24117.1 - 3.1e-47 161.3 19.9 6.2e-47 160.3 13.8 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO24117.1 - 2.3e-06 27.6 8.3 3.8e-05 23.6 3.4 3.5 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO24117.1 - 0.00057 20.3 6.0 0.13 12.7 1.2 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.6 EGO24117.1 - 0.09 12.7 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease BTB PF00651.26 EGO24118.1 - 0.024 14.6 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain SLY PF12485.3 EGO24118.1 - 0.13 12.5 2.6 0.2 11.8 1.8 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Amidohydro_1 PF01979.15 EGO24119.1 - 2.8e-38 132.4 0.0 3.6e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGO24119.1 - 1.6e-06 27.6 0.0 0.0032 16.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO24119.1 - 8.1e-06 25.5 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGO24119.1 - 0.0017 18.4 0.0 0.05 13.6 0.0 2.5 2 2 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 EGO24119.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase PLDc_2 PF13091.1 EGO24121.1 - 3.1e-13 49.5 0.0 2.2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGO24121.1 - 0.00097 18.8 1.3 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif SIR2 PF02146.12 EGO24122.1 - 1.5e-41 142.0 0.0 2.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TypeIII_RM_meth PF12564.3 EGO24122.1 - 0.026 14.4 0.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit Peptidase_S28 PF05577.7 EGO24123.1 - 3.8e-54 183.9 0.0 9.1e-54 182.6 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 HEAT PF02985.17 EGO24125.1 - 1.9e-19 67.9 1.2 0.0061 16.5 0.0 7.3 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.1 EGO24125.1 - 3.8e-09 36.7 0.1 0.018 15.3 0.0 4.1 3 1 0 4 4 4 2 HEAT repeats ASL_C2 PF14698.1 EGO24125.1 - 0.021 14.8 0.2 4.7 7.3 0.0 3.4 3 0 0 3 3 3 0 Argininosuccinate lyase C-terminal HEAT_EZ PF13513.1 EGO24125.1 - 0.19 12.2 0.5 43 4.7 0.0 3.8 3 1 0 3 3 3 0 HEAT-like repeat DUF2235 PF09994.4 EGO24126.1 - 0.11 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-Sec23_Sec24 PF04810.10 EGO24127.1 - 3.7 7.1 5.5 3.3 7.3 0.1 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger DUF2059 PF09832.4 EGO24128.1 - 0.084 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) YjeF_N PF03853.10 EGO24129.1 - 3.1e-41 140.7 0.0 4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 EGO24129.1 - 0.17 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-MYND PF01753.13 EGO24130.1 - 2.5e-11 43.2 2.3 7.9e-11 41.6 1.6 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EGO24130.1 - 2.2e-05 24.2 0.8 5.9e-05 22.8 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-DHHC PF01529.15 EGO24130.1 - 0.026 13.9 0.5 0.038 13.3 0.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2622 PF11080.3 EGO24131.1 - 0.0018 18.0 0.0 0.084 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2622) Transpos_assoc PF13963.1 EGO24131.1 - 0.03 14.2 0.3 0.59 10.1 0.0 2.5 2 1 0 2 2 2 0 Transposase-associated domain CRAL_TRIO PF00650.15 EGO24131.1 - 0.04 13.4 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain DDE_Tnp_4 PF13359.1 EGO24133.1 - 1.9e-29 102.2 0.0 2.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 EGO24133.1 - 0.00062 19.2 0.2 0.0013 18.1 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 EGO24133.1 - 0.0013 18.3 0.2 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain DUF2235 PF09994.4 EGO24135.1 - 5.5e-60 203.0 0.0 7.1e-59 199.4 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EGO24135.1 - 0.032 13.9 0.0 0.047 13.4 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cullin PF00888.17 EGO24136.1 - 1.1e-46 159.5 0.1 2.8e-46 158.2 0.0 1.6 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 EGO24136.1 - 3.1e-10 40.1 0.0 6.5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Peptidase_S9 PF00326.16 EGO24137.1 - 1.4e-14 53.8 0.4 6.1e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGO24137.1 - 2.9e-08 33.5 0.0 0.0025 17.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO24137.1 - 1.5e-07 31.2 0.0 7.3e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO24137.1 - 0.00046 20.1 0.2 0.001 19.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO24137.1 - 0.00065 19.1 0.1 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 EGO24137.1 - 0.00087 18.6 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EGO24137.1 - 0.0093 15.4 0.3 0.11 11.9 0.2 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Patatin PF01734.17 EGO24137.1 - 0.052 13.4 0.5 0.12 12.2 0.4 1.7 1 1 0 1 1 1 0 Patatin-like phospholipase DUF2048 PF09752.4 EGO24137.1 - 0.077 11.8 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Aldo_ket_red PF00248.16 EGO24138.1 - 1e-46 159.0 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.26 EGO24139.1 - 8.1e-05 22.5 0.0 0.00025 20.9 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ribonuc_red_lgC PF02867.10 EGO24141.1 - 1.8e-212 706.7 0.0 2.6e-212 706.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGO24141.1 - 6.3e-24 83.5 0.0 1.6e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGO24141.1 - 1.4e-15 57.4 0.1 3.9e-15 56.0 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Avl9 PF09794.4 EGO24143.1 - 6.7e-125 416.4 0.0 8.8e-125 416.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EGO24143.1 - 1.2e-08 34.6 0.0 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EGO24143.1 - 1.6e-07 30.8 0.7 0.016 14.4 0.2 2.9 2 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) PTH2 PF01981.11 EGO24144.1 - 3e-47 159.1 0.1 4.4e-47 158.5 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Rsm22 PF09243.5 EGO24144.1 - 0.086 11.8 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.20 EGO24145.1 - 6.6e-64 215.5 0.0 9e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO24145.1 - 4.4e-36 124.2 0.0 2.3e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO24145.1 - 7.6e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGO24145.1 - 0.0017 17.2 0.1 0.0032 16.3 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EGO24145.1 - 0.19 11.0 0.3 0.5 9.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family AMPKBI PF04739.10 EGO24146.1 - 1.9e-17 62.9 0.3 2.4e-17 62.6 0.2 1.3 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4541 PF15074.1 EGO24151.1 - 0.033 14.7 0.2 0.085 13.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) DUF957 PF06117.6 EGO24151.1 - 0.094 12.2 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) A_deaminase PF00962.17 EGO24152.1 - 2.7e-110 368.3 0.1 3.4e-110 368.0 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2235 PF09994.4 EGO24153.1 - 1.9e-70 237.3 0.0 2.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EGO24153.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 EGO24153.1 - 0.024 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 EGO24153.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aldedh PF00171.17 EGO24154.1 - 2.2e-183 609.8 0.9 2.5e-183 609.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO24154.1 - 4.3e-05 22.4 0.0 7.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) BHD_3 PF10405.4 EGO24155.1 - 5.8e-28 96.4 0.0 1.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EGO24155.1 - 3.9e-23 81.4 0.0 1.3e-22 79.7 0.0 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EGO24155.1 - 2.9e-19 68.3 0.0 7.8e-19 66.9 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGO24155.1 - 5.6e-12 45.7 0.2 5.6e-12 45.7 0.1 3.0 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EGO24155.1 - 5.9e-06 26.4 0.0 0.00012 22.2 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily GCD14 PF08704.5 EGO24156.1 - 2.8e-88 295.5 0.1 1.4e-86 290.0 0.1 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EGO24156.1 - 6.8e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO24156.1 - 0.00028 20.4 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGO24156.1 - 0.045 14.3 0.0 0.08 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EGO24156.1 - 0.058 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PAS_3 PF08447.6 EGO24157.1 - 2.1e-06 27.7 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EGO24157.1 - 2.9e-05 23.8 0.0 8.5e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 EGO24157.1 - 0.00091 19.1 0.0 0.0022 17.9 0.0 1.6 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 EGO24157.1 - 0.0031 17.8 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EGO24157.1 - 0.0055 16.7 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold Melibiase PF02065.13 EGO24158.1 - 4.9e-14 51.8 0.0 1.9e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Melibiase Peptidase_M3 PF01432.15 EGO24162.1 - 1e-132 443.4 0.0 2e-132 442.5 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 EGO24162.1 - 0.016 14.5 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.1 EGO24162.1 - 0.13 12.3 0.8 2.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Effector protein CAP PF00188.21 EGO24163.1 - 4.8e-22 78.7 2.0 6.3e-22 78.3 1.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Bud13 PF09736.4 EGO24164.1 - 8.6e-48 162.2 9.4 8.6e-48 162.2 6.5 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex PROL5-SMR PF15621.1 EGO24164.1 - 0.066 13.6 1.2 0.087 13.2 0.3 1.6 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family UvrD-helicase PF00580.16 EGO24167.1 - 2e-19 70.0 0.0 2.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EGO24167.1 - 7.9e-15 55.1 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain FH2 PF02181.18 EGO24167.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Sugar_tr PF00083.19 EGO24168.1 - 6.3e-109 364.5 30.4 8.3e-109 364.1 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO24168.1 - 5.8e-28 97.6 47.7 2e-20 72.8 11.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO24168.1 - 1.2e-07 30.4 38.9 2.2e-05 23.0 9.8 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 EGO24169.1 - 6.6e-24 84.2 16.3 7.3e-15 54.5 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2 PF00152.15 EGO24170.1 - 7.1e-78 261.7 0.1 1.1e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO24170.1 - 4.3e-09 36.0 0.1 1e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGO24170.1 - 0.0056 15.8 0.2 0.82 8.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.5 EGO24170.1 - 0.28 10.9 2.9 0.54 10.0 2.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2868 PF11067.3 EGO24170.1 - 1.1 8.3 4.6 1.5 7.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Peptidase_C14 PF00656.17 EGO24172.1 - 1.4e-35 123.1 0.0 5.7e-27 94.9 0.0 2.0 1 1 1 2 2 2 2 Caspase domain Metallophos PF00149.23 EGO24173.1 - 2.2e-07 30.4 0.2 3.7e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO24173.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGO24173.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily AIG2 PF06094.7 EGO24174.1 - 3.9e-12 46.5 0.0 5.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Aminotran_5 PF00266.14 EGO24175.1 - 1.9e-20 72.9 0.0 3.1e-19 68.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO24175.1 - 4.8e-08 32.3 0.0 9.8e-08 31.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGO24175.1 - 3.9e-05 22.8 0.1 0.00046 19.3 0.1 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EGO24175.1 - 0.012 14.1 0.1 0.037 12.4 0.1 1.7 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF2392 PF10288.4 EGO24176.1 - 1.5e-14 54.2 0.0 2.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Asn_synthase PF00733.16 EGO24176.1 - 0.024 14.1 0.0 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 Asparagine synthase Gin PF10764.4 EGO24176.1 - 0.27 10.9 6.2 3.2 7.5 0.1 3.0 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin Asp PF00026.18 EGO24177.1 - 3.8e-17 62.5 0.0 1.2e-14 54.3 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO24177.1 - 2.2e-07 31.3 0.1 0.0011 19.4 0.1 3.9 3 2 0 3 3 3 1 Aspartyl protease Shisa PF13908.1 EGO24177.1 - 0.005 17.0 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EGO24177.1 - 0.0091 14.3 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 EGO24177.1 - 0.019 14.4 0.2 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 EGO24177.1 - 0.071 12.4 1.8 0.15 11.4 1.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1191 PF06697.7 EGO24177.1 - 0.079 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) IncA PF04156.9 EGO24177.1 - 0.11 12.0 0.2 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 EGO24177.1 - 0.12 12.0 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Rhabdo_glycop PF00974.13 EGO24177.1 - 0.14 10.3 0.3 0.21 9.7 0.2 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Prominin PF05478.6 EGO24177.1 - 0.21 9.0 0.3 0.29 8.6 0.2 1.1 1 0 0 1 1 1 0 Prominin TMEM52 PF14979.1 EGO24177.1 - 0.21 11.4 1.4 1 9.2 1.3 1.8 2 0 0 2 2 2 0 Transmembrane 52 Adeno_E3_CR2 PF02439.10 EGO24177.1 - 0.22 11.0 5.1 0.43 10.1 3.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UPRTase PF14681.1 EGO24178.1 - 3.5e-49 166.8 0.0 4.8e-47 159.8 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRK PF00485.13 EGO24178.1 - 2.1e-42 144.8 1.1 1.4e-39 135.6 0.8 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EGO24178.1 - 0.0036 17.6 0.0 0.0078 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO24178.1 - 0.0039 17.9 0.0 0.011 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EGO24178.1 - 0.026 13.9 0.1 0.84 9.0 0.0 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase KAP_NTPase PF07693.9 EGO24178.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Glyco_trans_4_3 PF12000.3 EGO24178.1 - 0.15 11.7 0.0 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Gkycosyl transferase family 4 group Na_Ca_ex PF01699.19 EGO24179.1 - 4.8e-25 87.7 23.7 5.5e-14 51.9 6.4 3.3 3 0 0 3 3 3 3 Sodium/calcium exchanger protein COX5B PF01215.14 EGO24180.1 - 5.9e-39 132.8 0.0 7.1e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-H2C2_2 PF13465.1 EGO24184.1 - 2.7e-07 30.5 0.1 2.7e-07 30.5 0.1 3.7 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO24184.1 - 3.6e-05 23.7 23.0 0.0011 19.1 1.7 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger LIM PF00412.17 EGO24184.1 - 0.0031 17.5 3.7 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 LIM domain zf-C2H2 PF00096.21 EGO24184.1 - 0.0077 16.5 2.8 0.0077 16.5 2.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 EGO24184.1 - 0.01 16.0 12.4 0.16 12.2 2.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 EGO24184.1 - 0.015 14.8 8.0 0.69 9.6 0.2 2.5 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.3 EGO24184.1 - 0.021 14.9 13.0 0.41 10.8 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 EGO24184.1 - 0.094 12.6 6.1 0.23 11.3 4.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger Desulfoferrod_N PF06397.7 EGO24184.1 - 0.14 11.5 0.5 0.84 9.0 0.0 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-C2HC_2 PF13913.1 EGO24184.1 - 0.37 10.5 4.1 2.6 7.8 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met2 PF12907.2 EGO24184.1 - 0.47 10.4 8.1 5.3 7.0 1.4 2.4 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_2 PF12756.2 EGO24184.1 - 1.4 9.0 8.0 11 6.2 2.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_5 PF13893.1 EGO24187.1 - 4.3e-07 29.6 0.0 9.9e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO24187.1 - 3.3e-06 26.6 0.0 7.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO24187.1 - 3.2e-05 23.8 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO24187.1 - 0.0046 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DSS1_SEM1 PF05160.8 EGO24187.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 DSS1/SEM1 family WD40 PF00400.27 EGO24188.1 - 0.00051 19.8 5.7 6.2 6.8 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF2415 PF10313.4 EGO24188.1 - 0.00055 19.5 0.1 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) IKI3 PF04762.7 EGO24188.1 - 0.3 8.8 0.0 0.44 8.2 0.0 1.1 1 0 0 1 1 1 0 IKI3 family ABC_tran PF00005.22 EGO24189.1 - 4.9e-34 117.5 0.0 1e-33 116.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGO24189.1 - 8e-34 117.3 9.5 9.8e-34 117.0 6.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGO24189.1 - 2e-06 28.0 0.0 0.0059 16.6 0.0 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EGO24189.1 - 5.2e-06 25.8 0.5 0.0014 17.9 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGO24189.1 - 0.0017 19.1 0.0 0.0053 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO24189.1 - 0.0044 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EGO24189.1 - 0.0092 15.8 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO24189.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EGO24189.1 - 0.015 15.6 0.0 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO24189.1 - 0.02 15.1 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGO24189.1 - 0.025 14.7 0.0 0.31 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO24189.1 - 0.029 14.5 0.1 0.16 12.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO24189.1 - 0.033 13.3 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rop-like PF05082.8 EGO24189.1 - 0.06 12.8 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 1 0 Rop-like AAA_33 PF13671.1 EGO24189.1 - 0.07 13.0 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGO24189.1 - 0.078 12.9 2.9 0.29 11.0 0.2 3.1 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EGO24189.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EGO24189.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein LRR_4 PF12799.2 EGO24190.1 - 8e-26 89.1 33.5 7.5e-09 35.0 0.1 10.2 6 1 4 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO24190.1 - 1.7e-22 78.8 21.6 3.6e-12 45.8 3.3 8.4 9 1 0 9 9 9 4 Leucine rich repeat LRR_1 PF00560.28 EGO24190.1 - 1.7e-20 69.8 24.9 0.052 13.5 0.1 11.4 11 1 1 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 EGO24190.1 - 3.6e-17 60.4 19.8 0.033 14.2 0.0 10.3 10 0 0 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 EGO24190.1 - 2e-14 51.1 23.7 0.15 12.4 0.4 10.3 12 0 0 12 12 12 6 Leucine rich repeat LRR_9 PF14580.1 EGO24190.1 - 0.0013 18.3 0.2 0.027 14.0 0.0 2.8 2 1 0 2 2 2 1 Leucine-rich repeat FliG_N PF14842.1 EGO24190.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain zf-CCCH PF00642.19 EGO24191.1 - 4.3e-07 29.4 8.6 9.6e-06 25.1 0.7 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO24191.1 - 0.0021 17.9 0.4 0.0021 17.9 0.3 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type CART PF06373.6 EGO24191.1 - 0.23 11.4 1.3 4.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) PS_Dcarbxylase PF02666.10 EGO24192.1 - 1.8e-53 180.8 0.0 2.7e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EGO24192.1 - 3.7e-31 106.8 0.1 2.9e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 EGO24192.1 - 0.077 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 CEP76 C2 domain Biotin_lipoyl_2 PF13533.1 EGO24192.1 - 0.099 12.3 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like HMG_box PF00505.14 EGO24194.1 - 8.3e-05 22.7 0.7 0.00017 21.7 0.5 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO24194.1 - 0.00018 21.8 2.3 0.00043 20.6 1.6 1.7 1 0 0 1 1 1 1 HMG-box domain DUF4449 PF14613.1 EGO24195.1 - 8.5e-19 68.0 0.2 4.2e-18 65.7 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Hemerythrin PF01814.18 EGO24195.1 - 0.33 11.1 4.7 1.4 9.1 0.6 3.2 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain IncA PF04156.9 EGO24195.1 - 3.6 7.1 5.4 13 5.2 3.7 1.9 1 1 0 1 1 1 0 IncA protein Mito_carr PF00153.22 EGO24196.1 - 3.8e-57 189.9 0.0 2.5e-20 71.9 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4381 PF14316.1 EGO24198.1 - 0.051 13.6 0.2 0.056 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1546 PF07571.8 EGO24204.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) PrpF PF04303.8 EGO24207.1 - 1.7e-77 260.6 0.0 2e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 PrpF protein CDC27 PF09507.5 EGO24208.1 - 2.4e-12 46.8 11.3 3.7e-12 46.2 7.8 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PBP1_TM PF14812.1 EGO24208.1 - 0.027 14.7 4.1 0.027 14.7 2.9 2.5 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GMP_synt_C PF00958.17 EGO24211.1 - 9.5e-41 137.4 0.1 1.8e-40 136.5 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EGO24211.1 - 2.8e-33 114.9 0.0 4.9e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EGO24211.1 - 3.4e-10 39.2 0.2 2.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EGO24211.1 - 9.4e-10 38.2 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 EGO24211.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EGO24211.1 - 0.0032 16.0 0.1 0.0053 15.3 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EGO24211.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGO24211.1 - 0.011 14.9 0.8 0.021 14.0 0.0 2.0 2 1 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EGO24211.1 - 0.035 13.1 0.1 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 EGO24211.1 - 0.048 13.1 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Defensin_beta_2 PF13841.1 EGO24212.1 - 0.017 15.4 3.4 0.017 15.4 2.4 2.8 2 0 0 2 2 2 0 Beta defensin EB PF01683.13 EGO24212.1 - 4.2 7.5 20.9 3.4 7.8 1.8 3.8 2 2 1 3 3 3 0 EB module His_biosynth PF00977.16 EGO24213.1 - 3.2e-42 144.3 0.3 2.1e-41 141.7 0.2 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EGO24213.1 - 3e-29 101.8 0.0 4.8e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGO24213.1 - 7.2e-09 35.4 0.0 1.7e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EGO24213.1 - 1.3e-06 28.1 0.0 5.5e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 EGO24213.1 - 0.019 14.4 0.1 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Peptidase_S51 PF03575.12 EGO24213.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 SH3_2 PF07653.12 EGO24213.1 - 0.15 11.5 1.3 14 5.2 0.2 2.9 3 0 0 3 3 3 0 Variant SH3 domain MFS_1 PF07690.11 EGO24214.1 - 4.4e-26 91.4 24.7 4.4e-26 91.4 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IBN_N PF03810.14 EGO24216.1 - 0.0061 16.4 0.8 0.096 12.6 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain GHMP_kinases_N PF00288.21 EGO24216.1 - 0.17 12.0 3.1 6.8 6.8 0.7 2.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain MFS_1 PF07690.11 EGO24217.1 - 1.1e-25 90.1 25.0 1.1e-25 90.1 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.28 EGO24218.1 - 0.065 12.9 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 F-box domain TFIIF_beta PF02270.10 EGO24219.1 - 4.6e-50 170.9 0.0 2.7e-49 168.4 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Nucleoplasmin PF03066.10 EGO24219.1 - 0.65 9.5 5.7 1.2 8.6 3.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Fungal_trans PF04082.13 EGO24220.1 - 4.7e-34 117.4 0.1 8.2e-34 116.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 EGO24220.1 - 0.042 13.7 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Apc3 PF12895.2 EGO24220.1 - 0.099 12.7 0.8 0.27 11.3 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 EGO24221.1 - 2.3e-09 37.1 0.1 1.8e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO24221.1 - 8.3e-07 29.1 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO24221.1 - 2.1e-05 24.6 0.0 0.00012 22.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 EGO24221.1 - 5.6e-05 22.2 0.0 0.0066 15.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EGO24221.1 - 9.1e-05 22.6 0.0 0.00028 21.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EGO24221.1 - 0.00065 19.3 0.0 0.0041 16.7 0.0 2.0 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.1 EGO24221.1 - 0.00082 18.8 0.1 0.0025 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGO24221.1 - 0.0015 18.6 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EGO24221.1 - 0.006 15.7 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 EGO24221.1 - 0.0076 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein KAP_NTPase PF07693.9 EGO24221.1 - 0.019 13.9 0.1 0.52 9.2 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.1 EGO24221.1 - 0.027 15.2 0.0 0.062 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO24221.1 - 0.041 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 EGO24221.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Rad17 PF03215.10 EGO24221.1 - 0.073 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EGO24221.1 - 0.082 12.4 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGO24221.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO24221.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EGO24221.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain CAF-1_p60_C PF15512.1 EGO24221.1 - 0.11 12.8 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.27 EGO24222.1 - 9.6e-10 37.9 2.0 3.1e-08 33.1 0.1 2.3 2 1 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 EGO24223.1 - 3e-29 99.7 14.0 2.9e-12 45.9 0.2 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Gmad1 PF10647.4 EGO24223.1 - 0.00067 19.1 0.6 0.81 9.0 0.0 3.0 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EGO24223.1 - 0.012 15.2 8.4 2.6 7.8 0.0 4.1 5 1 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EGO24223.1 - 0.035 12.2 0.1 0.41 8.7 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Inositol_P PF00459.20 EGO24223.1 - 0.051 12.8 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Inositol monophosphatase family DUF1652 PF07865.6 EGO24223.1 - 0.074 12.6 0.0 5.6 6.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Proteasome_A_N PF10584.4 EGO24223.1 - 0.29 10.4 5.2 6.7 6.1 0.2 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3295 PF11702.3 EGO24228.1 - 1.2e-12 47.6 7.0 1.2e-12 47.6 4.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) Atrophin-1 PF03154.10 EGO24228.1 - 0.0026 16.0 2.3 0.0036 15.5 1.6 1.1 1 0 0 1 1 1 1 Atrophin-1 family Fungal_trans PF04082.13 EGO24230.1 - 3.7e-34 117.7 0.0 6e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO24230.1 - 0.0078 16.1 0.5 0.015 15.2 0.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EGO24232.1 - 1.2e-40 135.9 21.9 5.4e-15 54.6 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat NACHT PF05729.7 EGO24232.1 - 4.6e-08 32.8 0.1 3.1e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO24232.1 - 1.8e-07 31.3 0.1 4.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO24232.1 - 2.2e-05 24.6 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGO24232.1 - 0.00017 21.8 0.0 0.00063 19.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EGO24232.1 - 0.00089 18.3 0.0 0.026 13.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 EGO24232.1 - 0.003 17.2 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.1 EGO24232.1 - 0.0052 16.2 0.1 0.013 14.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain eIF2A PF08662.6 EGO24232.1 - 0.0066 16.1 0.0 1.8 8.2 0.0 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGO24232.1 - 0.019 14.6 0.1 11 5.7 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 EGO24232.1 - 0.025 14.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 EGO24232.1 - 0.033 12.9 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 EGO24232.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EGO24232.1 - 0.049 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 EGO24232.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 NTPase GalKase_gal_bdg PF10509.4 EGO24233.1 - 1.4e-06 27.4 0.0 2.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature WD40 PF00400.27 EGO24234.1 - 1e-110 358.1 61.6 6.3e-14 51.2 0.1 14.4 14 1 0 14 14 14 12 WD domain, G-beta repeat PD40 PF07676.7 EGO24234.1 - 2.9e-17 61.9 4.4 2.2 8.0 0.0 11.3 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat NACHT PF05729.7 EGO24234.1 - 5.1e-10 39.2 0.1 2.3e-09 37.1 0.1 2.1 1 1 0 1 1 1 1 NACHT domain Gmad1 PF10647.4 EGO24234.1 - 4.1e-09 36.1 0.5 0.0025 17.2 0.0 5.2 2 2 2 4 4 4 3 Lipoprotein LpqB beta-propeller domain AAA_16 PF13191.1 EGO24234.1 - 8.8e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.3 EGO24234.1 - 0.00012 20.4 5.3 3.4 5.7 0.0 6.2 4 2 1 6 6 6 1 Nucleoporin Nup120/160 AAA_22 PF13401.1 EGO24234.1 - 0.00026 21.1 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGO24234.1 - 0.0022 17.4 0.4 0.034 13.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EGO24234.1 - 0.0042 16.1 0.0 0.044 12.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EGO24234.1 - 0.009 16.2 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EGO24234.1 - 0.0092 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EGO24234.1 - 0.025 14.7 0.0 0.22 11.7 0.0 2.7 3 0 0 3 3 1 0 RNA helicase ArgK PF03308.11 EGO24234.1 - 0.048 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein BBS2_Mid PF14783.1 EGO24234.1 - 0.055 13.2 0.0 1 9.1 0.0 3.0 3 0 0 3 3 2 0 Ciliary BBSome complex subunit 2, middle region Robl_LC7 PF03259.12 EGO24234.1 - 0.082 12.4 0.0 36 4.0 0.0 4.1 5 0 0 5 5 4 0 Roadblock/LC7 domain AAA_19 PF13245.1 EGO24234.1 - 0.094 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF3312 PF11768.3 EGO24234.1 - 0.095 10.9 0.1 2 6.5 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3312) Zeta_toxin PF06414.7 EGO24234.1 - 0.1 11.6 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.9 EGO24234.1 - 0.14 11.0 0.0 0.6 9.0 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain CAF-1_p60_C PF15512.1 EGO24234.1 - 0.16 12.3 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal NTPase_1 PF03266.10 EGO24234.1 - 0.33 10.6 0.0 0.61 9.7 0.0 1.4 1 0 0 1 1 1 0 NTPase IKI3 PF04762.7 EGO24234.1 - 0.39 8.4 0.1 1.2 6.8 0.0 1.8 2 0 0 2 2 2 0 IKI3 family GalKase_gal_bdg PF10509.4 EGO24235.1 - 1.3e-20 72.3 0.1 2.5e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EGO24235.1 - 1.4e-14 54.0 0.0 4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGO24235.1 - 2.1e-11 43.7 2.1 1.1e-10 41.4 1.1 2.5 3 0 0 3 3 3 1 GHMP kinases N terminal domain Aldose_epim PF01263.15 EGO24236.1 - 7.9e-16 58.0 0.0 2.7e-14 52.9 0.0 2.7 1 1 0 1 1 1 1 Aldose 1-epimerase S10_plectin PF03501.10 EGO24238.1 - 9.2e-44 147.2 0.2 1.1e-43 146.9 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 EGO24238.1 - 0.0052 16.4 0.0 0.0078 15.9 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB ADH_zinc_N PF00107.21 EGO24239.1 - 1.8e-12 46.9 0.0 3.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO24239.1 - 2.5e-09 36.8 0.1 4.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PPI_Ypi1 PF07491.6 EGO24240.1 - 2.1e-25 88.1 3.2 3.7e-25 87.3 2.2 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 EGO24240.1 - 0.05 11.9 1.9 0.062 11.6 1.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-MYND PF01753.13 EGO24241.1 - 3.3e-10 39.6 9.5 7.9e-10 38.4 6.6 1.7 1 0 0 1 1 1 1 MYND finger DZR PF12773.2 EGO24241.1 - 0.63 9.9 8.6 17 5.3 6.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon IDO PF01231.13 EGO24243.1 - 2.8e-105 352.2 0.0 3.2e-105 351.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AAA PF00004.24 EGO24244.1 - 5.4e-14 52.5 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO24244.1 - 1.8e-09 37.8 0.0 3.7e-08 33.5 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 EGO24244.1 - 3.7e-07 29.9 0.0 1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.1 EGO24244.1 - 1.1e-06 28.7 0.0 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO24244.1 - 7.3e-05 21.8 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EGO24244.1 - 0.00021 20.9 0.0 0.00076 19.1 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EGO24244.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_11 PF13086.1 EGO24244.1 - 0.0056 16.2 0.9 0.0091 15.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EGO24244.1 - 0.014 15.1 0.0 0.11 12.1 0.0 2.6 2 1 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EGO24244.1 - 0.018 14.1 0.4 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 EGO24244.1 - 0.052 12.4 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EGO24244.1 - 0.077 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 EGO24244.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EGO24244.1 - 0.11 12.6 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mo-co_dimer PF03404.11 EGO24245.1 - 7.1e-53 177.7 0.2 1.2e-52 176.9 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EGO24245.1 - 4.3e-51 172.6 0.0 7.8e-51 171.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EGO24245.1 - 2.8e-25 88.3 0.0 5.1e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO24245.1 - 9.4e-23 80.8 0.0 2.4e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EGO24245.1 - 4e-19 68.1 0.0 1.5e-18 66.3 0.0 2.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EGO24245.1 - 0.00012 21.9 0.1 0.013 15.4 0.0 3.1 2 1 0 3 3 3 1 Ferric reductase NAD binding domain MFS_1 PF07690.11 EGO24246.1 - 5.1e-39 133.9 16.5 5.1e-39 133.9 11.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO24246.1 - 0.038 13.7 2.1 0.12 12.1 0.1 3.0 4 0 0 4 4 4 0 MFS_1 like family LacY_symp PF01306.14 EGO24246.1 - 0.039 12.5 8.2 0.15 10.5 0.3 3.0 2 1 1 3 3 3 0 LacY proton/sugar symporter Ribosomal_L4 PF00573.17 EGO24247.1 - 3.9e-43 147.0 1.6 3.9e-43 147.0 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EGO24247.1 - 3.1e-29 100.6 4.2 3.1e-29 100.6 2.9 2.5 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain E1_DerP2_DerF2 PF02221.10 EGO24248.1 - 2.4e-23 82.8 0.1 2.8e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGO24248.1 - 0.0007 19.6 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 ML-like domain Anophelin PF10731.4 EGO24248.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF2892 PF11127.3 EGO24249.1 - 2.5 7.9 0.0 2.5 7.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2892) Cytochrome_CBB3 PF13442.1 EGO24250.1 - 4.3e-09 36.3 0.7 6.5e-08 32.6 0.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EGO24250.1 - 5.3e-08 33.5 0.1 1.3e-07 32.3 0.1 1.6 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 EGO24250.1 - 6.9e-05 22.3 1.1 0.00072 19.0 0.7 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain DUF3365 PF11845.3 EGO24250.1 - 0.068 13.0 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Haem_bd PF14376.1 EGO24250.1 - 0.091 12.4 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain UPF0128 PF03673.8 EGO24250.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) NIR_SIR PF01077.17 EGO24251.1 - 9.7e-27 93.2 0.2 2.3e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.1 EGO24251.1 - 3.9e-21 74.7 0.0 2e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_2 PF07992.9 EGO24251.1 - 4.2e-20 72.4 0.0 2.9e-19 69.7 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO24251.1 - 3e-14 53.1 0.3 9.4e-14 51.5 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EGO24251.1 - 6.9e-14 51.6 4.6 7.8e-11 41.8 0.3 3.5 3 0 0 3 3 3 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 EGO24251.1 - 4.7e-11 42.1 0.1 2.2e-10 39.9 0.0 2.2 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EGO24251.1 - 7.1e-11 41.5 0.0 1.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain DAO PF01266.19 EGO24251.1 - 1.1e-05 24.5 0.2 0.016 14.1 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO24251.1 - 4.2e-05 23.3 0.7 0.039 13.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGO24251.1 - 0.00023 21.2 0.1 0.0023 18.0 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO24251.1 - 0.034 12.6 0.1 0.78 8.1 0.0 2.7 3 1 1 4 4 4 0 HI0933-like protein Shikimate_DH PF01488.15 EGO24251.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EGO24251.1 - 0.39 9.5 1.7 24 3.6 0.1 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGO24251.1 - 2.7 6.7 6.1 5 5.8 0.0 2.8 1 1 1 3 3 3 0 FAD binding domain PARP PF00644.15 EGO24252.1 - 4.5e-13 49.0 2.2 5.9e-10 38.9 1.5 3.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Paired_CXXCH_1 PF09699.5 EGO24252.1 - 0.017 14.6 3.6 2.7 7.5 0.2 3.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.1 EGO24252.1 - 8.3 6.1 14.1 9e+02 -0.4 9.7 3.0 1 1 0 1 1 1 0 Cytochrome c7 Coq4 PF05019.8 EGO24254.1 - 3.1e-93 310.7 0.0 3.6e-93 310.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SNAPc19 PF15497.1 EGO24255.1 - 0.11 12.7 0.9 0.12 12.6 0.6 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Gemini_AL1 PF00799.15 EGO24257.1 - 2.7e-14 52.9 0.0 4.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain Gemini_AL1_M PF08283.6 EGO24257.1 - 2.1e-11 43.5 0.7 4.1e-11 42.6 0.5 1.5 1 0 0 1 1 1 1 Geminivirus rep protein central domain AAA_17 PF13207.1 EGO24257.1 - 0.1 13.4 0.0 0.77 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO24257.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain GABP-alpha PF11620.3 EGO24258.1 - 3.6e-05 23.6 0.8 0.29 11.1 0.1 2.5 2 0 0 2 2 2 2 GA-binding protein alpha chain DUF2316 PF10078.4 EGO24258.1 - 0.00081 19.3 0.1 0.72 9.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2316) ubiquitin PF00240.18 EGO24258.1 - 0.0026 17.1 1.3 0.17 11.2 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin family UN_NPL4 PF11543.3 EGO24258.1 - 0.08 13.2 0.8 3.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Cpn60_TCP1 PF00118.19 EGO24259.1 - 1.4e-142 475.7 0.7 1.6e-142 475.5 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.23 EGO24260.1 - 1.4e-42 145.3 1.1 1.8e-42 145.0 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homez PF11569.3 EGO24260.1 - 0.09 11.8 0.4 0.18 10.8 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez cwf21 PF08312.7 EGO24260.1 - 0.13 12.1 0.8 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 cwf21 domain Sad1_UNC PF07738.8 EGO24261.1 - 6.5e-23 81.0 0.0 2.6e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF4618 PF15397.1 EGO24261.1 - 0.08 12.2 4.3 0.14 11.4 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Abhydrolase_1 PF00561.15 EGO24262.1 - 1.4e-28 99.9 0.0 8.5e-28 97.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO24262.1 - 6.8e-25 88.2 0.0 9.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24262.1 - 1.4e-13 50.8 0.0 1e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO24262.1 - 0.0035 17.1 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EGO24262.1 - 0.014 14.5 0.0 0.63 9.2 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF1057 PF06342.7 EGO24262.1 - 0.056 12.2 0.0 0.099 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.5 EGO24262.1 - 0.078 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 EGO24262.1 - 0.14 10.6 0.0 0.23 9.8 0.0 1.3 1 1 0 1 1 1 0 Ndr family CRAL_TRIO PF00650.15 EGO24263.1 - 1.3e-29 102.7 0.0 1.7e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO24263.1 - 4.3e-12 45.9 0.5 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain UBA_4 PF14555.1 EGO24263.1 - 0.0095 15.4 0.2 0.14 11.7 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain UBA PF00627.26 EGO24263.1 - 0.068 13.0 0.2 0.73 9.7 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain CRAL_TRIO_2 PF13716.1 EGO24263.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain ADH_N PF08240.7 EGO24264.1 - 4.7e-24 84.2 2.0 8.4e-24 83.4 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO24264.1 - 7.1e-13 48.2 0.0 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO24264.1 - 9.6e-05 21.6 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGO24264.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EGO24264.1 - 0.024 14.4 0.1 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N_2 PF13602.1 EGO24264.1 - 0.064 14.1 0.0 0.098 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EGO24264.1 - 0.12 12.0 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.7 EGO24265.1 - 2.7e-23 81.8 0.5 4.8e-23 80.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO24265.1 - 3.4e-16 58.9 0.0 5.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO24265.1 - 0.00013 21.1 0.1 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGO24265.1 - 0.00014 21.4 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EGO24265.1 - 0.0039 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGO24265.1 - 0.0057 16.3 0.1 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGO24265.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 EGO24265.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Lzipper-MIP1 PF14389.1 EGO24266.1 - 0.02 14.9 0.5 0.04 14.0 0.3 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Inhibitor_I68 PF10468.4 EGO24266.1 - 0.12 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Galactosyl_T PF01762.16 EGO24267.1 - 3e-10 40.0 0.0 6.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase ADH_N PF08240.7 EGO24268.1 - 9.5e-23 80.0 0.5 1.7e-22 79.2 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO24268.1 - 1.3e-14 53.8 0.0 2.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO24268.1 - 7.6e-05 21.9 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGO24268.1 - 0.0023 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EGO24268.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EGO24268.1 - 0.05 13.2 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EGO24268.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Thaumatin PF00314.12 EGO24269.1 - 2e-64 216.9 20.0 2.2e-64 216.8 13.8 1.0 1 0 0 1 1 1 1 Thaumatin family Toxin_47 PF15527.1 EGO24269.1 - 0.074 12.8 2.2 1.8 8.3 0.1 2.5 1 1 1 2 2 2 0 Putative toxin 47 Thaumatin PF00314.12 EGO24270.1 - 2e-64 216.9 20.0 2.2e-64 216.8 13.8 1.0 1 0 0 1 1 1 1 Thaumatin family Toxin_47 PF15527.1 EGO24270.1 - 0.074 12.8 2.2 1.8 8.3 0.1 2.5 1 1 1 2 2 2 0 Putative toxin 47 Oxidored_molyb PF00174.14 EGO24271.1 - 5e-46 156.1 0.0 7.1e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGO24271.1 - 1.1e-12 47.7 3.0 3.8e-12 45.9 0.5 2.5 2 1 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Gmad2 PF10648.4 EGO24271.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Oxidored_molyb PF00174.14 EGO24274.1 - 9.8e-53 178.0 0.0 1.4e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGO24274.1 - 6.4e-16 58.1 3.9 1e-11 44.5 0.5 3.1 2 1 1 3 3 3 2 Mo-co oxidoreductase dimerisation domain NUFIP1 PF10453.4 EGO24278.1 - 1.9e-14 52.8 0.0 3.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Sina PF03145.11 EGO24278.1 - 0.03 13.9 0.4 0.048 13.3 0.3 1.2 1 0 0 1 1 1 0 Seven in absentia protein family Peptidase_M16_C PF05193.16 EGO24279.1 - 3.8e-18 65.7 0.0 3.1e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGO24279.1 - 9.9e-11 41.6 0.1 3.6e-09 36.5 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) IncA PF04156.9 EGO24282.1 - 8.4 5.9 9.4 0.63 9.5 1.7 2.2 2 0 0 2 2 2 0 IncA protein Dabb PF07876.7 EGO24283.1 - 1.2e-18 67.2 0.0 1.4e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain G-patch PF01585.18 EGO24287.1 - 1e-09 37.9 0.1 1.8e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 EGO24287.1 - 9.2e-09 35.3 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.2 EGO24287.1 - 0.029 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 DExH-box splicing factor binding site Cyclin_N PF00134.18 EGO24289.1 - 1.1e-42 144.6 0.2 2.7e-42 143.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO24289.1 - 1.8e-26 92.4 0.0 3.4e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3400 PF11880.3 EGO24289.1 - 0.11 11.7 0.2 3.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) adh_short PF00106.20 EGO24290.1 - 1.8e-63 213.4 17.7 1.7e-33 115.8 2.8 2.8 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EGO24290.1 - 4.4e-29 100.3 0.0 8.6e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EGO24290.1 - 1.8e-28 99.4 12.1 1.3e-15 57.5 2.0 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 EGO24290.1 - 3.3e-11 43.0 0.0 9.8e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 EGO24290.1 - 0.00076 18.5 0.5 0.083 11.9 0.1 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EGO24290.1 - 0.015 14.9 1.5 0.015 14.9 1.0 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4161 PF13722.1 EGO24290.1 - 0.032 14.5 0.9 0.83 9.9 0.1 2.5 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DUF4468 PF14730.1 EGO24290.1 - 0.06 13.0 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Shikimate_DH PF01488.15 EGO24290.1 - 0.17 12.0 2.2 0.81 9.7 0.2 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EGO24290.1 - 0.56 10.0 5.9 1.3 8.8 0.6 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF543 PF04418.7 EGO24290.1 - 2.6 8.0 8.0 10 6.1 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Na_Ca_ex PF01699.19 EGO24291.1 - 2.1e-14 53.2 10.6 2.1e-14 53.2 7.4 2.8 2 1 0 2 2 2 1 Sodium/calcium exchanger protein m04gp34like PF12216.3 EGO24291.1 - 0.18 11.1 1.3 0.2 10.9 0.1 1.6 2 0 0 2 2 2 0 Immune evasion protein F-box-like PF12937.2 EGO24294.1 - 0.004 16.8 0.0 0.016 14.9 0.0 2.1 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EGO24294.1 - 0.0089 15.9 1.2 1.4 9.2 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat Erg28 PF03694.8 EGO24295.1 - 9e-39 131.9 4.8 1.1e-38 131.6 3.3 1.1 1 0 0 1 1 1 1 Erg28 like protein CS PF04969.11 EGO24297.1 - 2.1e-05 24.9 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 CS domain DMPK_coil PF08826.5 EGO24299.1 - 0.16 11.8 18.3 0.75 9.7 0.1 5.1 4 0 0 4 4 4 0 DMPK coiled coil domain like CorA PF01544.13 EGO24299.1 - 0.81 8.6 6.1 1.5 7.7 0.0 3.2 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein TPK_catalytic PF04263.11 EGO24301.1 - 4e-23 81.3 0.0 5.9e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EGO24301.1 - 5.9e-19 67.5 0.1 1.2e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF2499 PF10693.4 EGO24301.1 - 0.091 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) ThiS PF02597.15 EGO24302.1 - 3.7e-05 24.0 0.0 4.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family Lactamase_B PF00753.22 EGO24303.1 - 1.3e-06 28.2 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4078 PF13300.1 EGO24304.1 - 4e-20 71.7 1.8 4e-20 71.7 1.2 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4078) LRR_4 PF12799.2 EGO24305.1 - 1.2e-40 136.5 39.3 1.6e-09 37.1 3.7 7.5 4 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO24305.1 - 1.1e-25 89.1 33.3 5.7e-10 38.7 1.1 5.8 3 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 EGO24305.1 - 3.6e-18 65.7 9.9 3.2e-07 30.0 0.6 3.7 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 EGO24305.1 - 2.8e-16 57.0 33.5 0.73 10.0 0.2 11.0 12 0 0 12 12 12 9 Leucine Rich Repeat LRR_6 PF13516.1 EGO24305.1 - 5.7e-11 41.3 26.8 1.2 9.3 0.0 10.8 6 3 6 12 12 12 5 Leucine Rich repeat LRR_7 PF13504.1 EGO24305.1 - 5.4e-08 31.7 27.2 6.4 7.4 0.0 10.4 10 1 1 11 11 11 2 Leucine rich repeat LRR_5 PF13306.1 EGO24305.1 - 0.049 13.3 0.1 0.19 11.4 0.0 2.0 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) PAS_11 PF14598.1 EGO24306.1 - 0.026 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 EGO24306.1 - 0.05 13.6 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 PAS fold PAS PF00989.19 EGO24306.1 - 0.078 12.7 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.6 EGO24306.1 - 0.08 13.0 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 PAS fold Ank_5 PF13857.1 EGO24307.1 - 1.4e-15 56.9 0.1 2.4e-12 46.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO24307.1 - 6.4e-13 48.8 0.0 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO24307.1 - 9.2e-13 48.3 0.0 2.7e-12 46.8 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO24307.1 - 1.2e-11 43.7 1.0 3.1e-08 33.0 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EGO24307.1 - 6.8e-09 35.1 0.0 1e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ycf9 PF01737.12 EGO24308.1 - 0.052 12.9 0.5 0.08 12.3 0.3 1.2 1 0 0 1 1 1 0 YCF9 PRMT5 PF05185.11 EGO24309.1 - 7.5e-159 529.3 0.0 9e-159 529.1 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EGO24309.1 - 0.0096 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Phage_Coat_A PF05357.8 EGO24309.1 - 0.16 11.5 0.5 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Phage Coat Protein A AbrB-like PF14250.1 EGO24310.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Na_Ca_ex PF01699.19 EGO24311.1 - 6.2e-42 142.5 33.3 5.2e-27 94.1 5.7 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein MLANA PF14991.1 EGO24311.1 - 1.4 8.9 4.2 0.95 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein melan-A SGL PF08450.7 EGO24312.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EGO24312.1 - 0.13 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PFK PF00365.15 EGO24314.1 - 1e-162 539.7 0.2 6.2e-97 323.9 0.0 3.1 3 0 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 EGO24314.1 - 0.065 13.1 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 FAM216B protein family DUF1295 PF06966.7 EGO24315.1 - 4e-44 150.6 0.0 5.5e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EGO24315.1 - 1.5e-06 28.3 0.1 6.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO24315.1 - 0.0023 18.0 0.0 0.0064 16.5 0.0 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EGO24315.1 - 0.004 15.7 0.0 0.0081 14.7 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 EGO24315.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase GFA PF04828.9 EGO24316.1 - 1.1e-10 41.2 4.9 1.1e-10 41.2 3.4 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EGO24316.1 - 0.012 15.4 1.6 0.012 15.4 1.1 1.9 2 1 0 2 2 2 0 Cysteine-rich CWC PSD2 PF07624.6 EGO24317.1 - 0.1 12.2 0.5 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Mo25 PF08569.6 EGO24317.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Mo25-like TAP_C PF03943.8 EGO24319.1 - 9.1e-09 34.6 0.0 2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 EGO24319.1 - 1.1e-05 25.7 0.0 8.2e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 EGO24319.1 - 2.4e-05 23.8 6.3 9.3e-05 21.9 1.5 2.5 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) UBA_4 PF14555.1 EGO24319.1 - 0.00057 19.3 0.8 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain LRR_9 PF14580.1 EGO24319.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 EGO24319.1 - 0.13 12.5 3.1 89 3.9 0.1 3.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 EGO24319.1 - 1.1 9.0 7.1 1.5 8.6 1.9 2.4 1 1 0 1 1 1 0 Leucine rich repeat LRR_6 PF13516.1 EGO24319.1 - 3.4 8.0 6.6 2.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Vps39_1 PF10366.4 EGO24320.1 - 9.2e-29 99.6 0.5 3.2e-27 94.6 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EGO24320.1 - 2.8e-23 82.1 0.4 7.3e-23 80.8 0.3 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EGO24320.1 - 1.2e-15 57.7 0.0 2.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EGO24320.1 - 1.6e-15 56.9 1.3 4.6e-10 39.2 0.2 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Apc3 PF12895.2 EGO24320.1 - 0.0073 16.4 0.8 0.19 11.8 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGO24320.1 - 0.012 15.2 8.0 3.8 7.2 1.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24320.1 - 0.015 15.6 0.2 2.5 8.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO24320.1 - 0.016 14.9 0.2 10 6.1 0.2 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO24320.1 - 0.05 13.5 2.6 24 5.1 0.3 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGO24320.1 - 0.065 13.0 1.9 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO24320.1 - 1.1 9.2 4.4 41 4.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.1 EGO24322.1 - 0.00037 20.5 0.1 0.00049 20.1 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SPA PF08616.5 EGO24323.1 - 1.7e-06 27.7 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EGO24323.1 - 0.0024 17.9 0.0 0.0062 16.5 0.0 1.7 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking MFS_1 PF07690.11 EGO24324.1 - 5.5e-27 94.3 22.9 5.5e-27 94.3 15.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily zf-C4pol PF14260.1 EGO24326.1 - 0.23 11.4 8.0 0.2 11.6 3.1 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC PF00098.18 EGO24327.1 - 0.001 18.9 4.2 0.0019 18.0 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle ABC2_membrane PF01061.19 EGO24329.1 - 4e-34 117.6 20.3 4e-34 117.6 14.1 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGO24329.1 - 3.8e-27 95.2 0.0 6.9e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO24329.1 - 2.6e-09 37.4 0.1 1.1e-07 32.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGO24329.1 - 3.8e-05 22.8 25.2 3.8e-05 22.8 17.5 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EGO24329.1 - 0.00051 19.5 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO24329.1 - 0.00069 18.8 0.1 0.0018 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGO24329.1 - 0.00087 18.7 0.1 0.002 17.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain EGF_2 PF07974.8 EGO24329.1 - 0.00091 19.3 9.0 0.00091 19.3 6.3 3.4 3 0 0 3 3 2 2 EGF-like domain Rad17 PF03215.10 EGO24329.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ETF PF01012.16 EGO24329.1 - 0.012 15.3 0.1 0.035 13.8 0.1 1.7 2 0 0 2 2 1 0 Electron transfer flavoprotein domain SMC_N PF02463.14 EGO24329.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGO24329.1 - 0.039 13.0 0.0 4.2 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EGO24329.1 - 0.04 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO24329.1 - 0.086 13.6 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO24329.1 - 0.089 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO24329.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGO24329.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EGO24329.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO24329.1 - 0.16 11.4 0.6 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family hEGF PF12661.2 EGO24329.1 - 0.24 11.5 24.9 0.4 10.8 4.3 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF Glyco_transf_22 PF03901.12 EGO24330.1 - 2.5e-35 122.2 21.0 7.9e-35 120.6 14.6 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Sec7_N PF12783.2 EGO24330.1 - 0.19 11.1 1.2 0.34 10.3 0.9 1.4 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UPF0014 PF03649.8 EGO24331.1 - 1e-39 136.1 9.1 1.4e-39 135.7 6.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.17 EGO24331.1 - 0.0038 16.7 7.7 0.0038 16.7 5.3 2.4 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Tubulin_2 PF13809.1 EGO24331.1 - 0.0052 15.7 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Macoilin PF09726.4 EGO24332.1 - 1.8e-06 26.5 13.8 1.8e-06 26.5 9.5 2.1 2 0 0 2 2 2 1 Transmembrane protein IncA PF04156.9 EGO24332.1 - 4.8e-06 26.2 25.3 4.8e-06 26.2 17.6 2.3 1 1 1 2 2 2 1 IncA protein FliJ PF02050.11 EGO24332.1 - 0.004 17.1 22.0 0.004 17.1 15.3 3.0 1 1 1 2 2 2 1 Flagellar FliJ protein TMF_DNA_bd PF12329.3 EGO24332.1 - 0.0098 15.6 6.9 0.0098 15.6 4.8 4.0 1 1 4 5 5 5 2 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 EGO24332.1 - 0.078 12.2 36.2 0.01 15.1 16.6 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF724 PF05266.9 EGO24332.1 - 0.23 11.0 34.2 0.014 15.0 7.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF724) FliD_N PF02465.13 EGO24332.1 - 0.25 11.7 15.1 0.95 9.8 3.4 3.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 EGO24332.1 - 0.75 8.9 6.5 0.31 10.1 2.5 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1192 PF06698.6 EGO24332.1 - 2.2 8.1 14.8 2.5 7.9 0.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Baculo_PEP_C PF04513.7 EGO24332.1 - 3.3 7.5 7.1 0.49 10.2 1.5 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EGO24332.1 - 7.2 6.5 12.8 4 7.4 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EGO24332.1 - 9.5 6.5 8.0 21 5.4 0.2 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 EGO24332.1 - 10 6.0 37.9 2.6 7.8 5.7 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 EGO24333.1 - 3.5e-42 144.3 0.0 4.9e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO24333.1 - 5.5e-24 84.6 0.2 6.5e-21 74.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGO24333.1 - 5.6e-05 22.9 0.0 0.0055 16.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO24333.1 - 0.001 18.0 0.0 0.0028 16.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGO24333.1 - 0.075 12.3 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Zn-ribbon_8 PF09723.5 EGO24334.1 - 0.12 12.2 7.4 0.57 10.1 0.7 2.2 1 1 1 2 2 2 0 Zinc ribbon domain FeS PF04060.8 EGO24334.1 - 0.23 11.0 4.8 0.48 10.0 3.4 1.5 1 1 0 1 1 1 0 Putative Fe-S cluster Aminotran_1_2 PF00155.16 EGO24335.1 - 3.8e-26 91.9 0.0 4.7e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGO24335.1 - 1e-06 27.5 0.0 1.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase zf-CCHC PF00098.18 EGO24336.1 - 2.8e-08 33.2 1.1 4e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO24336.1 - 0.077 12.6 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO24336.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle PepSY_TM_1 PF13172.1 EGO24337.1 - 5.2 6.9 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix Retrotrans_gag PF03732.12 EGO24338.1 - 0.00028 20.8 0.3 0.00028 20.8 0.2 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein DUF4290 PF14123.1 EGO24340.1 - 0.044 12.9 0.3 0.1 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) CP12 PF02672.10 EGO24340.1 - 0.12 12.8 0.7 2.7 8.5 0.2 2.4 2 0 0 2 2 2 0 CP12 domain ADH_zinc_N PF00107.21 EGO24341.1 - 2.4e-10 40.0 0.0 4.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO24341.1 - 4.9e-10 39.1 0.0 1.3e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ala_racemase_N PF01168.15 EGO24343.1 - 4.1e-37 127.8 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MIS13 PF08202.6 EGO24344.1 - 1.1e-29 103.5 3.0 2.3e-29 102.4 2.1 1.5 1 1 0 1 1 1 1 Mis12-Mtw1 protein family zf-DHHC PF01529.15 EGO24345.1 - 1.2e-28 99.6 5.0 2.7e-28 98.5 3.4 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase GST_N PF02798.15 EGO24347.1 - 2.4e-16 59.6 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGO24347.1 - 9.7e-16 57.7 0.0 1.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO24347.1 - 2.7e-14 52.8 0.0 3.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO24347.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO24347.1 - 3.6e-09 36.3 0.0 5.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.5 EGO24347.1 - 0.005 16.8 0.5 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1912) GST_C_3 PF14497.1 EGO24347.1 - 0.022 15.2 0.1 0.035 14.5 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO24348.1 - 9e-15 54.6 0.0 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO24348.1 - 1.5e-12 47.5 0.0 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO24348.1 - 2.3e-11 43.5 0.0 3.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO24348.1 - 5.1e-11 42.4 0.0 8.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO24348.1 - 5.2e-06 26.2 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO24348.1 - 0.0067 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EGO24349.1 - 2.2e-48 164.9 0.0 4.1e-36 124.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cyclin_N PF00134.18 EGO24351.1 - 6.8e-13 48.2 0.0 4.6e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EGO24351.1 - 0.00015 21.4 0.0 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF1764 PF08576.5 EGO24352.1 - 7.5e-20 71.6 17.2 1.4e-19 70.7 5.2 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) DUF3742 PF12553.3 EGO24352.1 - 0.092 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Mitofilin PF09731.4 EGO24352.1 - 4.4 5.8 10.9 5.1 5.6 7.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ACBP PF00887.14 EGO24355.1 - 1.4e-31 108.0 0.7 1.6e-31 107.7 0.5 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.24 EGO24356.1 - 1.5e-34 118.2 0.6 1.8e-20 73.0 0.2 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EGO24356.1 - 1.6e-18 66.9 3.9 2.9e-08 33.9 3.2 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EGO24356.1 - 1.3e-10 41.0 0.1 1.1e-05 25.1 0.1 3.7 3 1 0 3 3 3 3 PH domain PH_8 PF15409.1 EGO24356.1 - 4.2e-09 36.3 1.6 5.3e-07 29.6 0.2 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 EGO24356.1 - 0.00042 20.4 2.9 0.07 13.2 0.9 3.3 2 2 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EGO24356.1 - 0.012 15.4 6.5 0.48 10.3 0.0 3.0 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 EGO24356.1 - 0.017 14.6 0.3 0.37 10.2 0.0 3.0 4 0 0 4 4 4 0 Pleckstrin homology domain ERM PF00769.14 EGO24356.1 - 0.32 10.5 1.1 2.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Zn_clus PF00172.13 EGO24357.1 - 1.2e-05 25.1 7.6 1.9e-05 24.4 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO24358.1 - 1.6e-35 122.4 0.0 1.9e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EGO24359.1 - 2.3e-48 164.7 0.7 2.3e-48 164.7 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO24359.1 - 7.2e-06 25.8 10.0 1.1e-05 25.1 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drf_GBD PF06371.8 EGO24360.1 - 6.1e-16 58.3 0.0 2.4e-12 46.5 0.0 2.5 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain GMC_oxred_N PF00732.14 EGO24361.1 - 3.6e-67 226.6 0.0 4.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO24361.1 - 2.1e-35 122.1 0.0 3.6e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGO24361.1 - 7.7e-07 28.2 1.0 0.00074 18.4 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO24361.1 - 9.4e-06 24.7 0.1 1.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO24361.1 - 1.9e-05 23.7 0.5 3.4e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO24361.1 - 0.00016 21.6 0.1 0.0004 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO24361.1 - 0.00093 18.3 0.1 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO24361.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO24361.1 - 0.0052 16.8 0.0 0.89 9.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO24361.1 - 0.014 15.7 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO24361.1 - 0.018 13.5 0.1 0.027 12.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EGO24361.1 - 0.041 13.6 0.7 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EGO24361.1 - 0.043 12.4 0.2 0.065 11.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EGO24361.1 - 0.18 10.8 0.4 0.28 10.1 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EGO24361.1 - 0.59 9.1 4.1 9.1 5.2 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase PEMT PF04191.8 EGO24362.1 - 1.7e-10 40.9 4.9 3.6e-08 33.4 1.2 2.2 1 1 1 2 2 2 2 Phospholipid methyltransferase ICMT PF04140.9 EGO24362.1 - 7.1e-09 35.7 0.6 7.1e-09 35.7 0.4 2.6 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EGO24362.1 - 0.035 12.6 0.0 0.048 12.1 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family BASP1 PF05466.7 EGO24364.1 - 0.12 12.2 8.6 0.16 11.8 5.9 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) ICMT PF04140.9 EGO24365.1 - 9e-13 48.2 0.1 1.4e-11 44.4 0.1 2.2 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO24365.1 - 4.5e-11 42.7 0.1 2e-09 37.4 0.1 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase CitMHS PF03600.11 EGO24365.1 - 0.0038 15.8 0.5 0.0049 15.4 0.4 1.1 1 0 0 1 1 1 1 Citrate transporter ERG4_ERG24 PF01222.12 EGO24365.1 - 0.033 12.7 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EGO24366.1 - 2.6e-14 53.1 0.7 9.8e-13 48.1 0.1 2.2 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO24366.1 - 1.8e-13 50.5 0.6 1.1e-11 44.7 0.1 2.2 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EGO24366.1 - 1.4e-05 23.8 0.0 1.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Glyco_transf_7N PF13733.1 EGO24368.1 - 0.091 12.1 0.3 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 CENP-Q PF13094.1 EGO24370.1 - 0.05 13.6 5.3 0.083 12.9 3.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.16 EGO24372.1 - 0.0041 17.0 2.9 0.0041 17.0 2.0 1.6 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.10 EGO24372.1 - 0.026 14.0 3.2 0.026 14.0 2.2 1.7 2 0 0 2 2 2 0 Septum formation initiator Microtub_assoc PF07989.6 EGO24372.1 - 0.029 14.1 3.6 0.037 13.8 2.0 1.5 1 1 0 1 1 1 0 Microtubule associated Kinesin-relat_1 PF12711.2 EGO24372.1 - 0.033 14.6 3.8 0.033 14.6 2.6 1.6 1 1 1 2 2 2 0 Kinesin motor FANCI_HD1 PF14679.1 EGO24372.1 - 0.05 13.3 0.2 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 FANCI helical domain 1 bZIP_2 PF07716.10 EGO24372.1 - 0.052 13.3 3.1 0.052 13.3 2.1 1.8 2 0 0 2 2 2 0 Basic region leucine zipper DUF1053 PF06327.9 EGO24372.1 - 0.057 13.7 0.6 0.075 13.3 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) HALZ PF02183.13 EGO24372.1 - 0.12 12.1 2.4 0.15 11.7 0.6 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF919 PF06034.6 EGO24372.1 - 0.15 11.6 5.9 0.25 10.9 4.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) IncA PF04156.9 EGO24372.1 - 0.31 10.6 6.6 0.4 10.2 4.6 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EGO24372.1 - 0.6 10.4 7.7 0.49 10.7 4.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF848 PF05852.6 EGO24372.1 - 0.73 9.6 5.7 0.83 9.4 3.6 1.3 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-H PF05837.7 EGO24372.1 - 1 9.5 5.7 1.4 9.1 3.3 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) ICMT PF04140.9 EGO24373.1 - 0.00028 21.0 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SMN PF06003.7 EGO24374.1 - 3.3e-07 29.6 1.2 5.1e-07 29.0 0.8 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 EGO24374.1 - 4.7e-05 23.2 0.0 0.00017 21.3 0.0 1.9 1 1 1 2 2 2 1 Tudor domain Relaxase PF03432.9 EGO24374.1 - 0.0057 16.0 4.0 0.0087 15.4 2.1 1.7 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain GAGA_bind PF06217.7 EGO24374.1 - 0.019 14.9 2.2 0.023 14.6 1.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Orbi_VP5 PF00901.12 EGO24374.1 - 0.18 9.9 3.9 0.29 9.2 2.7 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ndc1_Nup PF09531.5 EGO24374.1 - 0.25 9.7 2.2 0.28 9.5 1.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PDCD2_C PF04194.8 EGO24374.1 - 0.27 10.7 5.2 0.47 10.0 3.6 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain RR_TM4-6 PF06459.7 EGO24374.1 - 2.1 8.1 9.1 3.8 7.3 6.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 EGO24374.1 - 7.5 5.1 12.1 10 4.6 7.6 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RP-C_C PF11800.3 EGO24374.1 - 8.9 5.9 9.2 6.7 6.3 0.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region zf-CCHC_3 PF13917.1 EGO24376.1 - 1.3e-06 28.0 1.7 1.4e-06 27.9 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO24376.1 - 1.8e-05 24.4 5.2 2.4e-05 24.0 3.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO24376.1 - 0.22 11.0 3.1 0.32 10.4 2.2 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger NAD_binding_10 PF13460.1 EGO24378.1 - 4.2e-11 43.1 0.1 8.9e-11 42.1 0.1 1.5 2 0 0 2 2 1 1 NADH(P)-binding Epimerase PF01370.16 EGO24378.1 - 1.2e-09 37.9 0.0 6.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGO24378.1 - 7.7e-09 35.1 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EGO24378.1 - 3.9e-07 30.3 0.0 9.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGO24378.1 - 1.7e-05 24.8 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EGO24378.1 - 4.5e-05 22.4 0.1 0.00039 19.4 0.0 2.5 2 1 1 3 3 3 1 Male sterility protein Saccharop_dh PF03435.13 EGO24378.1 - 0.00029 19.9 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGO24378.1 - 0.0026 17.6 0.7 0.012 15.5 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EGO24378.1 - 0.0043 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EGO24378.1 - 0.0074 15.0 0.0 0.022 13.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EGO24378.1 - 0.062 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EGO24378.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 EGO24378.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TGF_beta_GS PF08515.7 EGO24379.1 - 0.44 9.9 2.1 0.62 9.4 0.7 1.9 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif ICMT PF04140.9 EGO24380.1 - 0.006 16.7 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family tRNA-synt_1g PF09334.6 EGO24381.1 - 3.2e-131 437.5 0.0 4.2e-131 437.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGO24381.1 - 3.4e-07 30.1 0.0 8e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA WHEP-TRS PF00458.15 EGO24381.1 - 5.2e-06 26.0 9.3 5.2e-06 26.0 6.5 2.1 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 EGO24381.1 - 7.5e-06 24.2 0.1 0.0023 16.0 0.0 3.1 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DUF1272 PF06906.6 EGO24381.1 - 0.3 10.9 3.1 0.17 11.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) C1_1 PF00130.17 EGO24381.1 - 0.48 10.2 2.1 1.3 8.8 1.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EGO24381.1 - 0.67 9.8 6.0 1.3 8.9 3.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF1610 PF07754.6 EGO24381.1 - 1.3 9.2 5.0 3.1 7.9 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF1289 PF06945.8 EGO24381.1 - 1.8 8.0 5.6 6.9 6.2 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) OPT PF03169.10 EGO24382.1 - 2.7e-139 465.4 21.7 3.1e-139 465.2 15.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lysis_S PF04971.7 EGO24382.1 - 0.046 13.4 4.8 1 9.1 0.1 3.2 3 0 0 3 3 3 0 Lysis protein S MFS_1 PF07690.11 EGO24383.1 - 1.3e-19 70.1 22.7 3.9e-19 68.5 9.9 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 EGO24383.1 - 0.0036 15.4 1.0 0.15 10.0 0.1 2.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family LCE PF14672.1 EGO24384.1 - 0.16 12.4 2.9 0.097 13.1 0.7 1.7 2 0 0 2 2 2 0 Late cornified envelope REV PF00424.13 EGO24384.1 - 1.5 8.7 7.8 0.86 9.5 3.6 1.7 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) p450 PF00067.17 EGO24385.1 - 3.4e-51 174.2 0.0 6.1e-51 173.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 EGF_CA PF07645.10 EGO24387.1 - 0.025 14.5 2.3 0.039 13.9 1.6 1.5 1 1 0 1 1 1 0 Calcium-binding EGF domain EGF_3 PF12947.2 EGO24387.1 - 0.22 11.5 1.2 0.38 10.7 0.8 1.5 1 1 0 1 1 1 0 EGF domain PAT1 PF09770.4 EGO24389.1 - 0.46 8.6 14.5 0.7 8.0 10.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EGO24389.1 - 0.92 8.8 15.1 1.3 8.3 10.5 1.3 1 0 0 1 1 1 0 Vta1 like Pol_alpha_B_N PF08418.5 EGO24389.1 - 1.2 8.5 9.0 1.9 7.9 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_UL32 PF06070.6 EGO24389.1 - 8.2 4.7 15.7 12 4.1 10.9 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 p450 PF00067.17 EGO24390.1 - 1.9e-57 194.8 0.0 3.1e-57 194.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DUF2622 PF11080.3 EGO24390.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) TPR_11 PF13414.1 EGO24391.1 - 2.3e-29 100.8 23.4 1.6e-07 30.8 0.8 10.0 6 2 4 11 11 11 8 TPR repeat CHAT PF12770.2 EGO24391.1 - 3.2e-25 88.8 0.1 1.8e-23 83.1 0.0 2.4 1 1 1 2 2 2 1 CHAT domain TPR_12 PF13424.1 EGO24391.1 - 5.1e-24 84.0 24.3 0.0023 17.8 0.0 13.1 5 1 9 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGO24391.1 - 1.9e-12 46.2 20.9 0.25 11.0 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGO24391.1 - 1e-11 44.0 4.6 0.76 10.1 0.0 10.4 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO24391.1 - 4.6e-07 29.2 14.4 0.31 11.0 0.3 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO24391.1 - 2e-05 25.0 20.7 0.17 12.5 0.0 9.0 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO24391.1 - 4.3e-05 22.9 2.7 5.5 7.0 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO24391.1 - 7.3e-05 23.0 20.3 2.9 8.7 0.0 10.0 8 3 4 12 12 11 1 Tetratricopeptide repeat MIT PF04212.13 EGO24391.1 - 0.00055 19.7 13.5 0.17 11.7 0.2 6.9 8 0 0 8 8 8 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EGO24391.1 - 0.0065 17.0 2.4 22 5.8 0.0 6.0 6 0 0 6 6 6 0 Sel1 repeat TPR_10 PF13374.1 EGO24391.1 - 2.1 8.3 27.3 1.6 8.8 0.1 8.7 11 0 0 11 11 10 0 Tetratricopeptide repeat Fra10Ac1 PF09725.4 EGO24394.1 - 5.8e-41 139.2 0.1 8e-41 138.8 0.1 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_11 PF00457.12 EGO24394.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 TPR_11 PF13414.1 EGO24395.1 - 2.3e-13 49.5 10.3 4.3e-13 48.6 2.1 4.0 3 1 2 5 5 5 2 TPR repeat TPR_2 PF07719.12 EGO24395.1 - 0.0004 20.0 12.4 0.36 10.8 0.8 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO24395.1 - 0.038 14.1 1.3 12 6.3 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 EGO24395.1 - 0.091 12.5 1.6 3.6 7.4 0.0 3.6 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.23 EGO24395.1 - 0.24 11.0 10.2 2.5 7.8 1.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24395.1 - 3.8 7.9 7.9 57 4.1 2.5 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ctf8 PF09696.5 EGO24397.1 - 2.6e-20 72.4 0.4 5.5e-20 71.3 0.3 1.5 1 1 0 1 1 1 1 Ctf8 Lipase_3 PF01764.20 EGO24398.1 - 4.9e-08 32.6 0.0 1.4e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO24398.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 EGO24398.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Trehalase PF01204.13 EGO24399.1 - 3.4e-165 550.5 0.1 4.2e-165 550.2 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EGO24399.1 - 2.1e-12 46.1 0.0 3.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CTP_transf_2 PF01467.21 EGO24399.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase ATG22 PF11700.3 EGO24402.1 - 3.3e-118 395.1 30.0 3.8e-118 395.0 20.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TraS PF10624.4 EGO24402.1 - 0.021 14.3 4.1 0.055 13.0 2.9 1.7 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Mitofilin PF09731.4 EGO24403.1 - 2.4e-116 389.7 19.1 3e-116 389.4 13.3 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Hpt PF01627.18 EGO24403.1 - 5.6 7.0 12.4 1.1 9.3 0.4 4.2 4 1 0 4 4 4 0 Hpt domain DUF1189 PF06691.6 EGO24404.1 - 0.048 12.9 0.1 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Nucleoporin_FG PF13634.1 EGO24405.1 - 6.1e-05 23.2 93.1 0.0001 22.4 19.4 3.8 2 1 2 4 4 4 2 Nucleoporin FG repeat region AceK PF06315.6 EGO24405.1 - 0.02 13.2 1.1 0.03 12.5 0.7 1.3 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DUF2067 PF09840.4 EGO24405.1 - 0.028 13.9 0.1 1.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) TBPIP PF07106.8 EGO24405.1 - 0.37 10.3 4.6 0.088 12.3 0.3 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 EGO24405.1 - 1.3 8.4 7.7 1.2 8.4 2.1 1.9 1 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.6 EGO24405.1 - 6 6.8 6.3 2.7 7.9 0.2 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Arrestin_N PF00339.24 EGO24406.1 - 0.00014 21.7 0.2 0.0012 18.6 0.1 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Mito_carr PF00153.22 EGO24407.1 - 1.2e-56 188.4 2.6 6.9e-21 73.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidohydro_1 PF01979.15 EGO24410.1 - 4.2e-61 207.4 2.2 6.2e-61 206.8 1.5 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EGO24410.1 - 8.4e-57 190.5 1.9 1.7e-56 189.5 1.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 EGO24410.1 - 4.5e-38 129.2 0.0 1.1e-37 127.9 0.0 1.7 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.15 EGO24410.1 - 8.9e-38 128.1 0.0 1.8e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_5 PF13594.1 EGO24410.1 - 4.4e-06 26.4 3.9 7.9e-06 25.6 1.6 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO24410.1 - 1.6e-05 24.3 0.6 0.00092 18.5 0.0 2.6 2 1 1 3 3 3 1 Amidohydrolase family DnaJ PF00226.26 EGO24416.1 - 5.7e-18 64.4 0.4 1.1e-17 63.4 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 EGO24416.1 - 3.5e-10 39.6 0.0 2.7e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EGO24418.1 - 1.3e-27 95.2 0.3 2e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO24418.1 - 9.4e-20 70.3 0.3 2.9e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DEAD PF00270.24 EGO24419.1 - 1.1e-33 116.1 0.2 1e-32 112.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO24419.1 - 6.5e-24 83.5 0.2 1.2e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGO24419.1 - 0.021 14.5 0.0 0.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Helicase_C_2 PF13307.1 EGO24419.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_30 PF13604.1 EGO24419.1 - 0.096 12.2 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Acyl_transf_1 PF00698.16 EGO24420.1 - 4.3e-65 220.1 0.1 1.6e-63 214.9 0.0 2.9 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EGO24420.1 - 9.6e-30 102.4 0.0 3.9e-29 100.5 0.0 2.1 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EGO24420.1 - 1.6e-28 98.2 0.8 4.3e-28 96.8 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 EGO24420.1 - 2.3e-25 89.5 0.1 5.4e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EGO24420.1 - 7.7e-21 74.9 0.0 2.2e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EGO24420.1 - 6e-16 58.3 0.1 1.2e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 EGO24420.1 - 1.7e-14 53.5 0.0 4.6e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.1 EGO24420.1 - 2.8e-14 53.0 0.8 1.6e-12 47.3 0.0 3.2 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase adh_short PF00106.20 EGO24420.1 - 3.4e-05 23.8 0.0 0.0022 17.9 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Abhydrolase_5 PF12695.2 EGO24420.1 - 0.011 15.4 0.1 0.75 9.5 0.0 3.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Gtr1_RagA PF04670.7 EGO24421.1 - 2.1e-53 180.8 0.0 2.6e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EGO24421.1 - 0.003 17.2 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Miro PF08477.8 EGO24421.1 - 0.005 17.3 0.0 0.0089 16.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGO24421.1 - 0.0058 15.8 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EGO24421.1 - 0.008 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.1 EGO24421.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGO24421.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation VTC PF09359.5 EGO24422.1 - 3.1e-95 318.4 0.1 1.1e-94 316.6 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EGO24422.1 - 1.3e-27 97.3 8.8 1.2e-26 94.1 2.2 2.9 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EGO24422.1 - 1.3e-09 38.1 1.7 2.8e-09 37.0 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.11 EGO24422.1 - 0.065 11.5 0.3 0.14 10.4 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family PTPlike_phytase PF14566.1 EGO24423.1 - 6.9e-122 402.6 0.0 1.5e-41 141.9 0.0 4.1 4 0 0 4 4 4 3 Inositol hexakisphosphate DSPc PF00782.15 EGO24423.1 - 9.6e-06 25.2 0.0 0.0082 15.7 0.0 3.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO24423.1 - 0.00029 20.2 0.0 0.38 10.0 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 EGO24423.1 - 0.016 15.0 0.0 14 5.7 0.0 3.2 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Ribosomal_S3_C PF00189.15 EGO24424.1 - 1.6e-16 60.2 0.0 3.1e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGO24424.1 - 2e-12 46.4 0.0 3.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EGO24424.1 - 0.046 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CVNH PF08881.5 EGO24427.1 - 6.6e-14 51.9 0.0 9.3e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 CVNH domain Zn_Tnp_IS91 PF14319.1 EGO24427.1 - 0.82 9.1 6.9 1.5 8.3 4.8 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain MARVEL PF01284.18 EGO24428.1 - 0.0014 18.4 8.7 0.002 17.9 6.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain AhpC-TSA PF00578.16 EGO24429.1 - 0.0001 21.9 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO24429.1 - 0.0016 17.9 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EGO24429.1 - 0.11 12.4 0.1 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like eIF-6 PF01912.13 EGO24430.1 - 1.6e-84 281.9 0.3 1.6e-84 281.9 0.2 1.6 2 0 0 2 2 2 1 eIF-6 family Methyltransf_28 PF02636.12 EGO24431.1 - 2.9e-67 226.7 0.0 3.7e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase GMC_oxred_N PF00732.14 EGO24432.1 - 1.6e-62 211.3 0.0 2.1e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO24432.1 - 4.9e-40 137.1 0.0 8.3e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGO24432.1 - 2.6e-06 26.5 0.0 4.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO24432.1 - 0.0001 21.3 0.3 0.00018 20.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGO24432.1 - 0.00016 20.6 1.3 0.014 14.2 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGO24432.1 - 0.0003 20.7 0.6 0.00093 19.1 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO24432.1 - 0.0022 17.1 0.1 0.0054 15.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO24432.1 - 0.04 12.3 0.1 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EGO24432.1 - 0.051 13.4 0.1 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO24432.1 - 0.1 11.6 0.2 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGO24432.1 - 0.11 12.9 2.4 0.44 10.9 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO24432.1 - 0.11 12.2 0.4 0.29 10.9 0.3 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding Asn_synthase PF00733.16 EGO24432.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Trp_halogenase PF04820.9 EGO24432.1 - 0.17 10.4 0.1 0.26 9.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RhoGAP PF00620.22 EGO24433.1 - 1.3e-38 131.9 0.0 2.1e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EGO24433.1 - 0.0076 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Glyco_hydro_17 PF00332.13 EGO24434.1 - 1.1e-06 27.9 3.7 3.1e-06 26.4 0.4 2.2 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 Varsurf_PPLC PF03490.8 EGO24434.1 - 0.023 14.3 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C UPF0016 PF01169.14 EGO24434.1 - 0.1 12.7 0.3 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 COQ9 PF08511.6 EGO24436.1 - 9.4e-05 21.8 0.2 0.00035 20.0 0.0 1.9 2 0 0 2 2 2 1 COQ9 Peptidase_C30 PF05409.8 EGO24437.1 - 0.037 13.1 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Vps51 PF08700.6 EGO24438.1 - 1.6e-23 82.2 2.0 2.2e-23 81.8 1.4 1.2 1 0 0 1 1 1 1 Vps51/Vps67 FlgN PF05130.7 EGO24438.1 - 0.00051 20.3 2.8 0.00071 19.8 2.0 1.1 1 0 0 1 1 1 1 FlgN protein Dor1 PF04124.7 EGO24438.1 - 0.0011 17.5 1.9 0.0014 17.1 1.3 1.0 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EGO24438.1 - 0.01 15.8 1.8 0.014 15.3 1.2 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 p450 PF00067.17 EGO24439.1 - 1.1e-75 254.9 0.0 1.4e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP_synt_H PF05493.8 EGO24440.1 - 1e-21 76.7 4.4 1.2e-21 76.5 3.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Competence PF03772.11 EGO24440.1 - 0.078 12.0 2.3 0.085 11.9 1.6 1.0 1 0 0 1 1 1 0 Competence protein DUF4131 PF13567.1 EGO24440.1 - 0.13 11.6 2.0 0.14 11.5 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ARL6IP6 PF15062.1 EGO24440.1 - 0.22 11.4 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix ABC2_membrane_4 PF12730.2 EGO24440.1 - 0.96 8.5 5.2 1.1 8.3 3.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 EGO24440.1 - 1.4 7.6 5.0 1.6 7.5 3.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Methyltransf_23 PF13489.1 EGO24441.1 - 0.00058 19.6 0.0 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO24441.1 - 0.03 14.6 0.0 0.21 11.9 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain G-alpha PF00503.15 EGO24442.1 - 5.7e-135 449.9 0.0 6.5e-135 449.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO24442.1 - 5.7e-13 48.4 0.1 1.5e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 EGO24442.1 - 0.00024 20.5 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 Ras family DUF3567 PF12091.3 EGO24442.1 - 0.0051 16.7 0.0 2.3 8.2 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3567) AAA_29 PF13555.1 EGO24442.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EGO24442.1 - 0.026 13.6 0.2 1.3 8.1 0.0 2.7 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO24442.1 - 0.042 14.3 0.0 0.89 10.0 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein THUMP PF02926.12 EGO24443.1 - 9.5e-09 35.2 0.6 2.1e-08 34.1 0.0 1.8 3 0 0 3 3 3 1 THUMP domain HLH PF00010.21 EGO24444.1 - 2.7e-06 26.9 0.4 7e-06 25.6 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NUDIX PF00293.23 EGO24445.1 - 2.7e-13 49.7 0.3 3.7e-13 49.2 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.17 EGO24446.1 - 1.3e-52 178.8 19.7 4.3e-50 170.5 13.7 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter HD PF01966.17 EGO24447.1 - 0.0089 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 HD domain GMC_oxred_N PF00732.14 EGO24448.1 - 8.6e-64 215.5 0.0 1.1e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO24448.1 - 2.3e-35 122.0 0.0 4.2e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGO24448.1 - 7.9e-05 21.7 0.3 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO24448.1 - 0.00032 19.6 0.7 0.23 10.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGO24448.1 - 0.00034 19.6 0.2 0.0022 17.0 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO24448.1 - 0.011 15.7 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO24448.1 - 0.016 14.3 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family PEX11 PF05648.9 EGO24450.1 - 1.8e-12 47.0 0.1 7.7e-11 41.6 0.1 2.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3106 PF11304.3 EGO24450.1 - 0.034 14.5 0.2 0.083 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Glyco_hydro_10 PF00331.15 EGO24451.1 - 1.7e-94 316.4 0.0 2e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EGO24451.1 - 0.042 12.9 0.1 0.26 10.3 0.0 1.9 1 1 1 2 2 2 0 Beta-galactosidase DUF427 PF04248.7 EGO24452.1 - 3.6e-37 125.9 0.1 7.1e-28 96.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) eIF-5_eIF-2B PF01873.12 EGO24453.1 - 7.8e-41 138.6 0.0 1.4e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EGO24453.1 - 8.1e-31 105.8 5.3 3.9e-30 103.6 0.3 2.8 2 1 0 2 2 2 2 eIF4-gamma/eIF5/eIF2-epsilon GSHPx PF00255.14 EGO24454.1 - 2.6e-40 136.1 0.0 3.3e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EGO24454.1 - 7.9e-05 22.3 0.1 0.00032 20.3 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO24454.1 - 0.0011 18.5 0.1 0.0022 17.5 0.1 1.6 1 1 0 1 1 1 1 Redoxin Pyridox_oxidase PF01243.15 EGO24455.1 - 4.4e-06 26.6 0.0 8.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FUSC PF04632.7 EGO24456.1 - 7.2 4.9 7.0 9.1 4.5 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Metallophos PF00149.23 EGO24457.1 - 1.8e-08 34.0 1.7 3.1e-08 33.2 1.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO24457.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 EGO24457.1 - 0.0094 14.0 0.1 0.068 11.2 0.0 2.0 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase AAA PF00004.24 EGO24459.1 - 6.8e-42 142.7 0.0 1.2e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO24459.1 - 2.1e-06 27.9 0.1 0.00036 20.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGO24459.1 - 4.4e-06 26.7 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGO24459.1 - 3.4e-05 22.8 0.0 6.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EGO24459.1 - 9.6e-05 22.1 0.2 0.0006 19.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO24459.1 - 0.00024 21.1 0.1 0.0016 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGO24459.1 - 0.00053 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGO24459.1 - 0.0038 17.1 0.0 0.0089 15.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EGO24459.1 - 0.0047 16.5 0.1 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGO24459.1 - 0.0057 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO24459.1 - 0.0072 16.0 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EGO24459.1 - 0.0074 15.4 0.2 0.22 10.6 0.1 2.2 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.12 EGO24459.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EGO24459.1 - 0.011 16.0 0.1 0.033 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGO24459.1 - 0.015 15.2 0.4 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO24459.1 - 0.017 15.9 0.1 0.017 15.9 0.1 2.3 2 2 0 2 2 1 0 AAA domain NACHT PF05729.7 EGO24459.1 - 0.022 14.4 0.3 0.42 10.2 0.1 2.6 2 1 1 3 3 3 0 NACHT domain NB-ARC PF00931.17 EGO24459.1 - 0.026 13.3 0.1 0.068 12.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EGO24459.1 - 0.035 13.5 0.7 1.9 7.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGO24459.1 - 0.043 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EGO24459.1 - 0.064 12.2 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EGO24459.1 - 0.067 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Viral_helicase1 PF01443.13 EGO24459.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EGO24459.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EGO24459.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Yip1 PF04893.12 EGO24460.1 - 1.2e-13 50.9 18.5 1.7e-13 50.4 12.8 1.2 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 EGO24460.1 - 0.026 14.4 2.7 0.026 14.4 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Phosphonate-bd PF12974.2 EGO24461.1 - 5.3e-08 32.5 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EGO24461.1 - 5e-06 26.2 0.0 8.6e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EGO24461.1 - 0.00027 20.4 0.1 0.00039 19.8 0.0 1.4 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.15 EGO24461.1 - 0.00069 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 STE3 PF02076.10 EGO24462.1 - 6.8e-51 173.0 15.0 7.4e-51 172.8 10.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF1970 PF09301.5 EGO24464.1 - 0.081 12.9 1.7 0.12 12.4 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Myb_DNA-bind_5 PF13873.1 EGO24467.1 - 0.066 13.1 0.3 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain GST_C_3 PF14497.1 EGO24468.1 - 0.00021 21.7 0.0 0.00036 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO24468.1 - 0.00039 20.5 0.0 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO24468.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO24468.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APG17 PF04108.7 EGO24469.1 - 3.2e-38 131.6 17.3 1.1e-31 110.0 7.9 2.6 2 1 0 2 2 2 2 Autophagy protein Apg17 Herpes_UL36 PF03586.8 EGO24469.1 - 0.03 13.4 1.4 0.071 12.2 0.6 1.9 1 1 0 1 1 1 0 Herpesvirus UL36 tegument protein SchA_CurD PF04486.7 EGO24469.1 - 0.1 12.4 0.3 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 SchA/CurD like domain DivIVA PF05103.8 EGO24469.1 - 0.14 12.2 5.5 1.2 9.2 0.2 2.7 1 1 1 2 2 2 0 DivIVA protein DUF4561 PF15120.1 EGO24469.1 - 0.16 11.4 2.0 2.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4561) Spc7 PF08317.6 EGO24469.1 - 0.23 10.0 8.5 0.29 9.7 4.7 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.10 EGO24469.1 - 0.81 9.3 10.0 0.79 9.4 0.4 3.5 3 1 0 4 4 4 0 RasGAP C-terminus STAT_int PF02865.12 EGO24469.1 - 0.89 9.5 5.4 0.44 10.5 1.3 2.3 2 0 0 2 2 2 0 STAT protein, protein interaction domain DUF2458 PF10454.4 EGO24469.1 - 1.1 9.1 8.8 37 4.1 3.7 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) FCD PF07729.7 EGO24469.1 - 1.3 9.3 11.2 0.34 11.2 3.0 2.8 1 1 1 2 2 2 0 FCD domain DUF2746 PF10874.3 EGO24469.1 - 5.1 7.3 8.5 0.63 10.2 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) V_ATPase_I PF01496.14 EGO24469.1 - 8.1 4.1 6.2 18 3.0 4.2 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 EGO24469.1 - 10 6.6 12.1 0.63 10.4 1.0 3.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal LysM PF01476.15 EGO24470.1 - 8.3e-06 25.5 0.0 8.8e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 LysM domain NACHT PF05729.7 EGO24472.1 - 1.5e-05 24.6 0.1 3.2e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EGO24472.1 - 0.00046 19.1 0.0 0.00064 18.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EGO24472.1 - 0.017 15.2 0.1 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoU_div PF01865.11 EGO24472.1 - 0.022 13.9 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 N2227 PF07942.7 EGO24472.1 - 0.042 12.7 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein ResIII PF04851.10 EGO24472.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AA_permease_N PF08403.5 EGO24472.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal RuBisCO_small PF00101.15 EGO24473.1 - 0.073 12.9 0.0 0.079 12.8 0.0 1.0 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain DUF496 PF04363.7 EGO24473.1 - 0.076 12.8 0.0 0.081 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF896 PF05979.7 EGO24473.1 - 0.12 11.9 0.4 0.21 11.2 0.2 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Aldo_ket_red PF00248.16 EGO24474.1 - 2.9e-71 239.5 0.0 3.3e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TEX19 PF15553.1 EGO24474.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Acyl-CoA_dh_1 PF00441.19 EGO24475.1 - 3.8e-30 104.9 0.3 5.5e-30 104.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO24475.1 - 3.9e-18 64.7 0.5 9e-18 63.5 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EGO24475.1 - 5.2e-17 61.4 0.0 1.3e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EGO24475.1 - 1.5e-11 44.8 0.0 4.1e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO24475.1 - 0.0015 18.8 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2945 PF11160.3 EGO24476.1 - 5.2e-05 22.9 3.3 0.01 15.6 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2945) CBM_5_12 PF02839.9 EGO24476.1 - 0.87 9.2 4.0 44 3.7 0.0 3.1 3 0 0 3 3 3 0 Carbohydrate binding domain BTB PF00651.26 EGO24477.1 - 0.0036 17.2 0.1 0.027 14.4 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain MIF4G PF02854.14 EGO24478.1 - 3.8e-24 85.2 2.5 3.8e-24 85.2 1.7 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGO24478.1 - 1.4e-18 66.6 0.2 9.9e-18 63.9 0.0 2.6 2 0 0 2 2 2 1 MA3 domain Imm3 PF14425.1 EGO24478.1 - 0.038 13.9 0.5 0.33 10.9 0.0 2.7 3 0 0 3 3 3 0 Immunity protein Imm3 DnaJ PF00226.26 EGO24479.1 - 0.00024 20.7 0.1 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGO24479.1 - 0.0099 15.6 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 1 Pam16 AAA_12 PF13087.1 EGO24481.1 - 1.2e-25 90.0 0.4 2.8e-25 88.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO24481.1 - 5.3e-05 22.9 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGO24481.1 - 0.0011 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF1661 PF07877.6 EGO24481.1 - 0.16 11.4 0.4 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) AAA_11 PF13086.1 EGO24482.1 - 3.4e-27 95.5 0.4 1.1e-15 57.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EGO24482.1 - 2.9e-14 53.0 0.0 5.3e-13 48.9 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGO24482.1 - 1.2e-12 47.3 0.0 2.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_12 PF13087.1 EGO24482.1 - 1.1e-10 41.2 0.0 1.7e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EGO24482.1 - 1.1e-05 24.6 0.0 3.8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_16 PF13191.1 EGO24482.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 EGO24482.1 - 5e-05 23.0 0.2 0.00053 19.6 0.1 2.2 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.4 EGO24482.1 - 6.3e-05 22.1 0.1 0.021 13.7 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EGO24482.1 - 9.7e-05 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO24482.1 - 0.00066 19.8 0.0 0.0081 16.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EGO24482.1 - 0.0012 18.4 0.0 0.0036 16.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_17 PF13207.1 EGO24482.1 - 0.0017 19.1 0.3 0.02 15.7 0.2 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO24482.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 EGO24482.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 1 1 Archaeal ATPase UvrD-helicase PF00580.16 EGO24482.1 - 0.0053 16.0 0.3 0.093 12.0 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.4 EGO24482.1 - 0.0056 15.3 0.3 0.013 14.1 0.0 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EGO24482.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EGO24482.1 - 0.0074 16.4 0.1 0.024 14.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Herpes_ori_bp PF02399.10 EGO24482.1 - 0.0079 14.2 0.0 0.013 13.5 0.0 1.2 1 0 0 1 1 1 1 Origin of replication binding protein Viral_helicase1 PF01443.13 EGO24482.1 - 0.0082 15.6 0.2 0.42 10.1 0.0 2.4 1 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 EGO24482.1 - 0.01 14.6 0.0 0.023 13.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EGO24482.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGO24482.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGO24482.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.4 1 1 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EGO24482.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EGO24482.1 - 0.025 14.0 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EGO24482.1 - 0.028 13.9 0.1 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO24482.1 - 0.03 14.6 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO24482.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGO24482.1 - 0.041 14.2 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain PIF1 PF05970.9 EGO24482.1 - 0.043 12.7 0.0 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Rad17 PF03215.10 EGO24482.1 - 0.05 12.2 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EGO24482.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zot PF05707.7 EGO24482.1 - 0.076 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_5 PF07728.9 EGO24482.1 - 0.079 12.6 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO24482.1 - 0.083 11.9 0.1 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGO24482.1 - 0.11 12.3 0.3 0.29 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Flavi_DEAD PF07652.9 EGO24482.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Carn_acyltransf PF00755.15 EGO24483.1 - 1.2e-135 452.9 0.0 1.4e-135 452.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DnaJ PF00226.26 EGO24484.1 - 7.2e-16 57.6 0.4 7.2e-16 57.6 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain NGP1NT PF08153.7 EGO24484.1 - 0.23 11.3 5.7 0.066 13.1 0.5 2.4 1 1 1 2 2 2 0 NGP1NT (NUC091) domain CtaG_Cox11 PF04442.9 EGO24485.1 - 3.7e-56 189.1 0.0 5e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 XPG_N PF00752.12 EGO24486.1 - 1e-31 109.1 0.0 1.4e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGO24487.1 - 6e-26 90.3 0.0 1.2e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EGO24487.1 - 0.0027 17.2 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EGO24487.1 - 0.019 15.1 0.0 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NDUF_B8 PF05821.6 EGO24488.1 - 5.3e-06 26.2 0.0 7.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_11 PF08241.7 EGO24489.1 - 6.1e-13 49.0 0.0 1.6e-12 47.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO24489.1 - 8.4e-11 41.8 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO24489.1 - 5.6e-09 36.5 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO24489.1 - 1.3e-08 34.2 0.0 2.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGO24489.1 - 8.3e-08 32.6 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO24489.1 - 1.6e-07 31.0 0.0 3.4e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO24489.1 - 2.6e-07 30.9 0.0 5.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO24489.1 - 1.4e-06 28.2 0.0 9.8e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO24489.1 - 0.0017 17.4 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EGO24489.1 - 0.0031 16.8 0.0 0.012 15.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EGO24489.1 - 0.018 13.3 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.14 EGO24489.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EGO24489.1 - 0.048 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EGO24489.1 - 0.061 12.9 0.0 0.49 9.9 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 EGO24489.1 - 0.24 10.4 0.0 0.67 8.9 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_M24 PF00557.19 EGO24490.1 - 4.8e-24 85.0 0.7 6.7e-24 84.6 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GPI-anchored PF10342.4 EGO24491.1 - 0.034 14.6 0.4 0.034 14.6 0.3 1.8 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BACON PF13004.2 EGO24491.1 - 0.064 13.4 0.8 0.11 12.7 0.6 1.5 1 1 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Citrate_synt PF00285.16 EGO24492.1 - 6.7e-114 380.3 0.0 7.8e-114 380.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase TPR_11 PF13414.1 EGO24493.1 - 1.3e-11 43.9 3.7 0.00014 21.4 0.2 3.1 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGO24493.1 - 1.1e-09 37.5 8.7 0.0032 17.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO24493.1 - 1e-08 35.0 0.3 0.031 14.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO24493.1 - 4e-07 29.3 9.3 0.00028 20.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24493.1 - 6e-07 29.7 0.9 3.9e-05 23.9 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO24493.1 - 1.2e-05 25.8 4.2 0.11 13.2 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO24493.1 - 1.5e-05 25.0 1.2 9.4e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGO24493.1 - 6.3e-05 22.8 2.4 0.0082 16.0 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO24493.1 - 0.00025 21.0 1.1 0.054 13.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 EGO24493.1 - 0.00037 20.5 0.1 4.5 7.7 0.0 3.5 3 1 0 3 3 3 2 Pentatricopeptide repeat domain TPR_7 PF13176.1 EGO24493.1 - 0.00071 19.1 0.5 0.49 10.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO24493.1 - 0.00095 19.4 1.7 0.49 10.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO24493.1 - 0.002 17.8 2.6 0.027 14.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EGO24493.1 - 0.0025 17.2 8.9 0.0043 16.4 0.3 2.9 3 0 0 3 3 3 1 26S proteasome subunit RPN7 PPR PF01535.15 EGO24493.1 - 0.0049 16.7 1.8 0.14 12.2 0.1 3.2 3 1 1 4 4 4 1 PPR repeat TPR_20 PF14561.1 EGO24493.1 - 1.8 8.7 6.5 3.7 7.7 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat ATPase_gene1 PF09527.5 EGO24494.1 - 4.4 7.1 5.7 1.3 8.8 0.4 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Med26 PF08711.6 EGO24496.1 - 1.9e-10 40.0 0.0 5.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2058 PF09831.4 EGO24496.1 - 5.7 6.7 9.5 1.3 8.8 3.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Bcl-2 PF00452.14 EGO24497.1 - 0.096 12.8 0.0 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family zf-CCHC PF00098.18 EGO24498.1 - 1.9e-06 27.5 3.2 4.2e-06 26.4 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO24498.1 - 0.00011 22.2 2.0 0.0016 18.4 1.4 2.5 1 1 0 1 1 1 1 Retrotransposon gag protein DUF3415 PF11895.3 EGO24500.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) GST_N_3 PF13417.1 EGO24501.1 - 0.00053 20.1 0.0 0.0016 18.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO24501.1 - 0.002 17.9 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO24501.1 - 0.0039 17.1 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO24501.1 - 0.018 15.4 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Memo PF01875.12 EGO24502.1 - 1.6e-73 246.9 0.0 1.9e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein GST_C_3 PF14497.1 EGO24503.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO24503.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2256 PF10013.4 EGO24503.1 - 0.38 10.5 3.1 0.74 9.6 2.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Actin PF00022.14 EGO24504.1 - 9.3e-80 267.9 0.0 1.3e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Actin UPF0061 PF02696.9 EGO24505.1 - 2.2e-92 309.8 0.0 3.1e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family CoA_transf_3 PF02515.12 EGO24507.1 - 9.7e-44 148.8 0.0 1.3e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 EGO24509.1 - 3.1e-32 111.7 0.2 4.8e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO24509.1 - 4.3e-20 70.9 0.3 9.1e-20 69.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EGO24509.1 - 9.5e-17 60.5 0.1 1.9e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EGO24509.1 - 2.6e-13 50.5 0.0 6.7e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO24509.1 - 5.4e-06 26.6 0.1 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COLFI PF01410.13 EGO24509.1 - 0.054 12.8 0.6 1.1 8.6 0.2 2.2 2 0 0 2 2 2 0 Fibrillar collagen C-terminal domain Alph_Pro_TM PF09608.5 EGO24510.1 - 0.033 13.7 0.1 0.093 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Herpes_gE PF02480.11 EGO24510.1 - 0.068 11.4 1.2 0.08 11.2 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 EGO24510.1 - 0.09 12.1 0.1 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Ctr PF04145.10 EGO24510.1 - 0.11 12.5 0.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family EXOSC1 PF10447.4 EGO24511.1 - 4.7e-20 71.3 0.2 8e-20 70.5 0.2 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGO24511.1 - 0.029 13.6 0.3 0.029 13.6 0.2 2.1 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Epimerase PF01370.16 EGO24512.1 - 2.9e-10 39.9 0.0 9.8e-10 38.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGO24512.1 - 1.6e-09 37.3 0.0 2.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO24512.1 - 8.3e-09 35.6 0.1 1.2e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGO24512.1 - 3.6e-05 24.0 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EGO24512.1 - 0.00011 21.2 0.0 0.00034 19.6 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein TrkA_N PF02254.13 EGO24512.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EGO24512.1 - 0.00021 20.0 0.0 0.00033 19.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.21 EGO24512.1 - 0.028 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.20 EGO24512.1 - 0.064 13.1 0.6 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EGO24512.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EGO24513.1 - 2.1e-10 40.9 0.1 4.3e-10 39.8 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO24513.1 - 9.4e-09 35.0 0.0 1.3e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGO24513.1 - 1.6e-08 34.1 0.1 2.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EGO24513.1 - 2.3e-05 24.6 0.1 4.7e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGO24513.1 - 0.00011 21.0 0.0 0.00013 20.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGO24513.1 - 0.00012 22.0 0.1 0.00047 20.1 0.0 2.1 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_4 PF07993.7 EGO24513.1 - 0.00022 20.2 0.0 0.00048 19.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 EGO24513.1 - 0.00075 18.5 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGO24513.1 - 0.069 13.0 0.9 0.81 9.5 0.6 2.5 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EGO24516.1 - 1.5e-10 41.3 0.1 3.5e-10 40.1 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO24516.1 - 3.4e-09 36.4 0.0 6.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGO24516.1 - 7.9e-09 35.1 0.1 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EGO24516.1 - 1.7e-07 31.5 0.1 3.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EGO24516.1 - 1.4e-05 24.1 0.1 0.00033 19.6 0.0 2.8 2 1 1 3 3 3 1 Male sterility protein TrkA_N PF02254.13 EGO24516.1 - 4.3e-05 23.4 0.1 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 EGO24516.1 - 0.00029 19.9 0.1 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EGO24516.1 - 0.0012 19.1 0.1 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EGO24516.1 - 0.0063 16.4 0.5 0.024 14.5 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO24516.1 - 0.0063 15.2 0.0 0.017 13.8 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EGO24516.1 - 0.04 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EGO24516.1 - 0.083 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EGO24516.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EGO24516.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EGO24517.1 - 1.5e-11 44.6 0.1 2.6e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO24517.1 - 7.8e-10 38.3 0.1 1.3e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGO24517.1 - 8.9e-10 38.3 0.0 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EGO24517.1 - 2.4e-08 34.3 0.2 5e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EGO24517.1 - 1.6e-05 24.0 0.1 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EGO24517.1 - 3.7e-05 23.7 0.0 9.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 EGO24517.1 - 0.00034 20.7 0.1 0.00079 19.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EGO24517.1 - 0.00081 19.7 0.1 0.0028 18.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 EGO24517.1 - 0.0014 17.5 0.0 0.0084 15.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EGO24517.1 - 0.0029 16.3 0.0 0.0068 15.1 0.0 1.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EGO24517.1 - 0.052 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SH3_9 PF14604.1 EGO24519.1 - 0.00018 20.9 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO24519.1 - 0.0092 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain WD40 PF00400.27 EGO24520.1 - 3.7e-13 48.7 8.6 0.04 13.8 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF2370 PF10176.4 EGO24521.1 - 2.1e-27 95.9 0.5 2.3e-27 95.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) CobS_N PF12556.3 EGO24521.1 - 0.15 11.4 1.7 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Cobaltochelatase CobS subunit N terminal Rsm1 PF08600.5 EGO24523.1 - 8e-14 51.2 0.2 2.7e-10 39.9 0.0 2.9 3 0 0 3 3 3 2 Rsm1-like zf-C3HC PF07967.8 EGO24523.1 - 1.6e-07 31.1 0.0 5.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like DM PF00751.13 EGO24523.1 - 0.3 10.6 5.4 2.2 7.9 0.1 2.6 3 0 0 3 3 3 0 DM DNA binding domain DUF4524 PF15025.1 EGO24524.1 - 0.0046 16.4 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) RNase_H2-Ydr279 PF09468.5 EGO24524.1 - 0.19 10.8 1.2 0.24 10.5 0.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) U79_P34 PF03064.11 EGO24524.1 - 0.31 10.5 7.4 0.43 10.0 5.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF788 PF05620.6 EGO24524.1 - 4.9 6.9 6.6 7.6 6.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF2992 PF11208.3 EGO24524.1 - 9.2 6.1 15.5 15 5.4 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Ribosomal_L10 PF00466.15 EGO24527.1 - 6.4e-25 86.9 0.3 2.9e-24 84.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EGO24527.1 - 7.2e-20 71.1 10.6 2.1e-19 69.7 5.6 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 EGO24527.1 - 0.038 13.8 0.2 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Glyco_transf_20 PF00982.16 EGO24529.1 - 3.9e-187 622.4 0.0 4.2e-141 470.6 0.0 1.9 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EGO24529.1 - 0.018 14.4 0.1 5.6 6.3 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 EGO24534.1 - 6.1e-56 189.0 0.9 6.1e-56 189.0 0.7 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO24534.1 - 3.7e-46 156.9 4.6 3.7e-46 156.9 3.2 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO24534.1 - 2.6e-26 93.3 0.0 8.1e-26 91.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO24534.1 - 9.3e-19 67.1 0.0 2.1e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO24534.1 - 5.4e-14 52.8 0.0 5.4e-13 49.5 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO24534.1 - 1.2e-08 34.2 0.4 9.7e-07 28.1 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO24534.1 - 0.00021 20.9 0.1 0.038 13.5 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3317 PF11779.3 EGO24535.1 - 5e-15 54.6 1.8 7.4e-15 54.1 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Virul_fac_BrkB PF03631.10 EGO24535.1 - 0.065 12.5 0.5 0.068 12.5 0.3 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF3733 PF12534.3 EGO24535.1 - 0.082 12.2 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 SAD_SRA PF02182.12 EGO24537.1 - 4.8e-45 152.6 0.0 6.4e-45 152.2 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain Serinc PF03348.10 EGO24538.1 - 1.2e-156 521.7 7.6 1.4e-156 521.5 5.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3661 PF12400.3 EGO24538.1 - 0.0072 16.4 8.2 0.024 14.7 0.0 3.2 2 1 1 3 3 3 2 Vaculolar membrane protein Rad51 PF08423.6 EGO24539.1 - 6.6e-06 25.2 0.0 1.8e-05 23.7 0.0 1.5 1 1 1 2 2 2 1 Rad51 AAA_25 PF13481.1 EGO24539.1 - 0.0054 16.1 0.1 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGO24539.1 - 0.021 13.9 0.0 0.17 10.9 0.0 2.0 1 1 1 2 2 2 0 KaiC CobU PF02283.11 EGO24539.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1805 PF08827.6 EGO24539.1 - 0.16 11.8 0.1 39 4.1 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1805) Caleosin PF05042.8 EGO24541.1 - 9.8e-47 158.7 0.0 1.2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Maf1 PF09174.5 EGO24542.1 - 3.2e-37 128.0 0.2 4e-30 104.9 0.0 2.9 2 1 0 2 2 2 2 Maf1 regulator SCP2 PF02036.12 EGO24543.1 - 1.2e-22 80.0 0.2 1.7e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGO24543.1 - 0.00034 20.5 0.1 0.00044 20.2 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Dynamin_N PF00350.18 EGO24544.1 - 2e-42 144.8 0.0 5.5e-42 143.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EGO24544.1 - 2.2e-09 36.5 0.0 5.8e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EGO24544.1 - 0.002 18.0 0.0 0.0068 16.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO24544.1 - 0.0038 17.6 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGO24544.1 - 0.0044 17.0 3.1 0.45 10.4 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 EGO24544.1 - 0.1 12.5 0.5 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DHDPS PF00701.17 EGO24545.1 - 1.5e-42 145.1 0.0 1.8e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EGO24545.1 - 0.00015 21.0 0.0 0.00022 20.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase p450 PF00067.17 EGO24547.1 - 2.4e-63 214.2 0.0 2.9e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO24548.1 - 2.2e-69 234.1 0.0 2.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_41 PF13844.1 EGO24549.1 - 9.2e-74 248.0 5.8 2.9e-44 150.8 0.2 3.6 3 1 0 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 EGO24549.1 - 3e-11 42.7 0.8 8.5e-07 28.5 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGO24549.1 - 8.5e-09 34.6 1.0 0.0063 16.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO24549.1 - 5.6e-07 29.4 0.0 2.6e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO24549.1 - 1.3e-06 28.0 0.0 0.067 13.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO24549.1 - 4.8e-06 26.0 0.0 0.89 9.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO24549.1 - 5.3e-05 23.4 0.0 0.1 13.2 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO24549.1 - 0.0001 21.8 0.0 5.3 7.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO24549.1 - 0.00019 22.0 0.1 0.00078 20.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO24549.1 - 0.00068 19.4 0.0 0.39 10.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO24549.1 - 0.0021 18.4 0.0 1.5 9.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO24549.1 - 0.007 16.0 0.1 3.7 7.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24549.1 - 0.026 14.8 0.2 0.069 13.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGO24549.1 - 0.17 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_2 PF07719.12 EGO24550.1 - 2.1e-30 102.1 10.8 2.2e-06 27.1 0.0 9.5 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGO24550.1 - 2.3e-30 104.0 0.3 6e-12 45.0 0.0 6.7 6 1 2 8 8 8 4 TPR repeat TPR_1 PF00515.23 EGO24550.1 - 2.5e-27 93.2 3.0 4.4e-09 35.5 0.0 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGO24550.1 - 9.7e-26 89.5 7.6 1.1e-13 50.8 0.1 8.4 6 2 3 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO24550.1 - 1.4e-23 82.8 0.7 3.8e-08 33.3 0.0 6.3 4 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGO24550.1 - 5.5e-20 71.4 8.7 1.3e-07 32.0 0.0 8.0 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24550.1 - 1.2e-19 70.3 0.2 1.4e-05 25.2 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO24550.1 - 1.5e-18 65.1 0.0 1e-05 24.9 0.0 7.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO24550.1 - 1.6e-15 55.5 8.2 0.00083 18.9 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO24550.1 - 3e-14 51.9 0.6 0.053 13.7 0.0 7.9 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO24550.1 - 1.5e-13 50.0 4.7 0.0053 17.2 0.0 8.5 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGO24550.1 - 1.3e-10 40.8 9.0 0.00012 21.9 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO24550.1 - 1.7e-09 37.5 18.9 0.0024 18.2 0.0 8.6 11 0 0 11 11 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO24550.1 - 2.3e-05 24.1 0.4 0.0034 17.2 0.1 4.1 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EGO24550.1 - 8.1e-05 22.4 9.8 0.0053 16.5 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGO24550.1 - 0.021 13.9 4.0 0.51 9.3 0.1 4.2 3 3 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 EGO24550.1 - 0.055 12.6 0.4 2.3 7.2 0.2 2.9 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP YfiO PF13525.1 EGO24550.1 - 0.073 12.5 0.1 4 6.8 0.0 3.1 4 0 0 4 4 3 0 Outer membrane lipoprotein TPR_3 PF07720.7 EGO24550.1 - 0.089 12.6 4.5 9.7 6.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Cohesin_load PF10345.4 EGO24550.1 - 0.089 10.9 0.3 1.5 6.9 0.0 2.7 3 1 1 4 4 4 0 Cohesin loading factor Coatomer_E PF04733.9 EGO24550.1 - 0.093 11.9 0.2 1.6 7.8 0.0 2.9 3 1 1 4 4 4 0 Coatomer epsilon subunit TPR_4 PF07721.9 EGO24550.1 - 0.26 11.8 4.1 21 5.9 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 EGO24552.1 - 6.9e-17 60.8 0.0 1.5e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO24552.1 - 8.9e-14 51.2 0.0 2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO24552.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EGO24553.1 - 9.2e-48 162.9 24.6 1.2e-47 162.5 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO24553.1 - 2.6e-19 69.1 31.7 4.1e-15 55.3 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.10 EGO24554.1 - 4.2e-11 42.4 0.1 4.2e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO24554.1 - 4.1e-10 39.7 0.8 5.6e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGO24554.1 - 0.012 16.0 0.4 0.018 15.5 0.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like eIF-1a PF01176.14 EGO24555.1 - 3e-29 100.2 0.2 4.2e-29 99.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ank_2 PF12796.2 EGO24556.1 - 8e-11 42.1 0.0 3.3e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO24556.1 - 5e-06 26.0 0.0 0.55 10.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGO24556.1 - 0.00058 20.0 0.0 0.18 12.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO24556.1 - 0.0018 18.7 0.3 0.0053 17.2 0.1 1.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO24556.1 - 0.014 15.6 0.0 34 5.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat DUF3746 PF12562.3 EGO24556.1 - 0.088 12.6 5.4 13 5.7 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3746) Macro PF01661.16 EGO24557.1 - 1.6e-41 140.9 0.1 2.2e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Macro domain Pkinase PF00069.20 EGO24558.1 - 2.7e-62 210.2 0.0 3.6e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO24558.1 - 7.4e-37 126.8 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO24558.1 - 3.5e-08 32.7 0.0 5.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO24558.1 - 0.00086 19.1 0.4 0.0016 18.2 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO24558.1 - 0.015 14.3 0.3 0.03 13.3 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MBOAT_2 PF13813.1 EGO24561.1 - 8.7e-19 67.3 2.6 3.1e-18 65.6 1.8 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Phenol_Hydrox PF02332.13 EGO24561.1 - 0.14 11.4 0.4 2.3 7.4 0.2 2.1 2 0 0 2 2 2 0 Methane/Phenol/Toluene Hydroxylase MBOAT_2 PF13813.1 EGO24562.1 - 2.8e-15 56.1 5.8 2.4e-14 53.1 3.1 2.7 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Nucleo_P87 PF07267.6 EGO24563.1 - 0.0085 14.8 0.4 0.061 12.0 0.6 1.8 2 0 0 2 2 2 1 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.27 EGO24563.1 - 0.012 15.4 0.0 0.078 12.9 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat CDC45 PF02724.9 EGO24563.1 - 6.1 4.7 7.8 9.4 4.1 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGO24563.1 - 6.7 6.2 17.5 0.21 11.1 5.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 EGO24563.1 - 7.2 4.3 11.9 12 3.6 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family CBS PF00571.23 EGO24564.1 - 2.4e-30 104.0 2.4 1.9e-12 46.7 0.0 4.6 4 1 1 5 5 5 4 CBS domain Epimerase PF01370.16 EGO24566.1 - 1.5e-22 80.2 0.0 2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO24566.1 - 2.2e-12 47.3 0.0 2.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO24566.1 - 7.2e-10 38.0 0.0 9.9e-10 37.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO24566.1 - 6.1e-06 25.3 0.0 7.7e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EGO24566.1 - 0.00039 19.7 0.0 0.00057 19.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EGO24566.1 - 0.0018 17.2 0.1 0.0047 15.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 EGO24566.1 - 0.0053 16.6 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CHASE2 PF05226.6 EGO24566.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain NPR3 PF03666.8 EGO24567.1 - 1.5e-60 205.0 0.3 4.7e-60 203.4 0.2 1.8 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Abhydrolase_6 PF12697.2 EGO24568.1 - 8.1e-13 48.7 0.0 6e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24568.1 - 5.2e-10 39.2 0.0 7.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO24568.1 - 7.9e-09 35.3 0.0 5.4e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO24568.1 - 4.8e-05 22.9 0.0 0.00024 20.6 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) VirJ PF06057.6 EGO24568.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Cutinase PF01083.17 EGO24568.1 - 0.053 13.2 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.3 EGO24568.1 - 0.091 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase LIP PF03583.9 EGO24568.1 - 0.098 11.8 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.13 EGO24568.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family SAD_SRA PF02182.12 EGO24569.1 - 2.4e-20 72.3 0.2 2.8e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 SAD/SRA domain Acetyltransf_3 PF13302.1 EGO24570.1 - 8.4e-25 87.5 0.0 1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO24570.1 - 1.3e-08 34.8 0.1 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO24570.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.19 EGO24570.1 - 0.029 14.4 0.0 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Exo_endo_phos PF03372.18 EGO24571.1 - 1.8e-13 51.0 0.3 8.4e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family ARID PF01388.16 EGO24571.1 - 7.3e-07 28.9 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain LIN37 PF15306.1 EGO24571.1 - 2.7 7.9 7.8 0.94 9.4 0.3 3.3 3 0 0 3 3 3 0 LIN37 DUF572 PF04502.8 EGO24573.1 - 7.6e-57 192.9 3.3 9.5e-57 192.6 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) IBB PF01749.15 EGO24573.1 - 1.6 8.9 10.6 4.1 7.6 6.8 1.9 1 1 1 2 2 2 0 Importin beta binding domain Ribosomal_S10 PF00338.17 EGO24574.1 - 1.1e-30 105.2 0.6 1.3e-30 105.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CW_binding_2 PF04122.7 EGO24574.1 - 0.059 13.5 0.1 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 SNARE_assoc PF09335.6 EGO24575.1 - 3.2e-11 43.5 4.9 3.2e-11 43.5 3.4 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein VEFS-Box PF09733.4 EGO24575.1 - 2.7 7.6 4.2 5 6.7 0.0 2.2 1 1 1 2 2 2 0 VEFS-Box of polycomb protein DnaJ PF00226.26 EGO24577.1 - 8.4e-19 67.0 0.0 2.2e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.14 EGO24578.1 - 5.7e-39 133.3 0.0 8e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGO24578.1 - 0.00047 19.8 0.0 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EGO24578.1 - 0.0022 17.7 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGO24578.1 - 0.071 13.2 0.0 0.44 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EGO24578.1 - 0.12 11.6 0.2 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein Frag1 PF10277.4 EGO24579.1 - 3.8e-24 85.3 15.0 3.8e-24 85.3 10.4 2.3 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EGO24579.1 - 5.9e-06 26.4 0.9 7.7e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family TM1586_NiRdase PF14512.1 EGO24579.1 - 0.13 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Putative TM nitroreductase RMP PF14996.1 EGO24579.1 - 0.41 10.5 0.7 0.74 9.7 0.5 1.3 1 0 0 1 1 1 0 Retinal Maintenance Adaptin_N PF01602.15 EGO24580.1 - 1.1e-123 413.3 4.3 1.7e-123 412.7 3.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGO24580.1 - 2.3e-09 37.3 0.3 0.0015 18.7 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EGO24580.1 - 6.3e-05 22.7 1.8 5.2 7.4 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EGO24580.1 - 0.0002 21.7 0.4 1.6 9.3 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EGO24580.1 - 0.0066 16.3 0.4 3.1 7.8 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion COX6B PF02297.12 EGO24581.1 - 5.1e-16 58.4 3.2 7.1e-16 57.9 2.2 1.3 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EGO24581.1 - 0.024 14.5 2.4 0.041 13.8 1.6 1.4 1 0 0 1 1 1 0 CHCH domain Prp18 PF02840.10 EGO24582.1 - 5.1e-58 195.0 0.1 5.1e-58 195.0 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EGO24582.1 - 3.8e-12 45.2 5.5 7.9e-12 44.2 3.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pex19 PF04614.7 EGO24582.1 - 0.38 10.3 5.6 1.1 8.7 3.5 2.1 1 1 1 2 2 2 0 Pex19 protein family zf-C2H2_jaz PF12171.3 EGO24583.1 - 4.1e-11 42.6 0.2 5.7e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO24583.1 - 1.6e-09 37.6 0.5 2.2e-09 37.1 0.3 1.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGO24583.1 - 0.0027 17.7 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGO24583.1 - 0.008 16.4 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO24583.1 - 0.023 15.0 0.1 0.032 14.5 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2387 PF09526.5 EGO24583.1 - 0.076 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-Tim10_DDP PF02953.10 EGO24584.1 - 5.7e-22 76.7 4.0 7.6e-22 76.3 2.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AflR PF08493.5 EGO24584.1 - 0.041 12.9 0.2 0.042 12.8 0.2 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Cytomega_TRL10 PF06084.6 EGO24584.1 - 0.053 13.3 1.5 0.064 13.0 1.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Homeobox PF00046.24 EGO24585.1 - 6.1e-18 64.1 2.3 1e-17 63.4 1.6 1.4 1 0 0 1 1 1 1 Homeobox domain UbiA PF01040.13 EGO24586.1 - 2.6e-29 102.2 17.8 3.7e-29 101.7 12.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NAPRTase PF04095.11 EGO24588.1 - 1.3e-53 181.8 0.1 1.8e-53 181.3 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Citrate_synt PF00285.16 EGO24589.1 - 2.9e-97 325.5 0.0 3.5e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EGO24589.1 - 0.049 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone SNAPc19 PF15497.1 EGO24590.1 - 0.047 13.8 0.8 0.049 13.8 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 WD40 PF00400.27 EGO24591.1 - 1.7e-05 24.5 0.0 0.0094 15.8 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3774 PF12609.3 EGO24592.1 - 0.032 15.0 1.4 0.056 14.3 0.0 2.0 2 0 0 2 2 2 0 Wound-induced protein P34-Arc PF04045.9 EGO24593.1 - 1.7e-105 351.6 1.0 2.1e-105 351.3 0.7 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RRM_1 PF00076.17 EGO24594.1 - 2.3e-14 52.7 0.0 3.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO24594.1 - 1.4e-09 37.8 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EGO24595.1 - 8.6e-44 149.4 0.0 1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 EGO24596.1 - 6.1e-46 155.7 0.0 7.1e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO24596.1 - 2.1e-20 73.3 0.0 3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO24596.1 - 6.7e-05 22.1 0.0 7.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO24596.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EGO24596.1 - 0.02 14.8 0.1 0.028 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EGO24596.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EGO24597.1 - 9.1e-48 161.9 0.0 3.4e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO24597.1 - 7.8e-28 96.1 0.0 1.7e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO24597.1 - 1.2e-06 28.4 0.0 5.4e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGO24597.1 - 0.016 13.6 0.0 0.075 11.4 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EGO24597.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 EGO24597.1 - 0.047 13.2 0.0 0.32 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain GRP PF07172.6 EGO24597.1 - 1 9.8 24.6 2.4 8.7 17.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family Retrotrans_gag PF03732.12 EGO24598.1 - 1e-05 25.4 2.9 2.8e-05 24.0 0.7 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO24598.1 - 1.4e-05 24.7 2.0 1.4e-05 24.7 1.4 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO24598.1 - 0.07 12.8 0.2 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.7 EGO24599.1 - 0.00034 20.4 8.2 0.00034 20.4 5.7 1.4 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EGO24599.1 - 0.0019 16.2 7.8 0.0021 16.0 5.4 1.1 1 0 0 1 1 1 1 Nop14-like family Nop53 PF07767.6 EGO24599.1 - 0.0021 17.1 4.3 0.0032 16.5 3.0 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) YL1 PF05764.8 EGO24599.1 - 0.0022 17.6 13.5 0.0039 16.8 9.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.9 EGO24599.1 - 0.0094 14.0 11.3 0.012 13.7 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein SR-25 PF10500.4 EGO24599.1 - 0.027 13.9 11.5 0.045 13.2 8.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4636 PF15468.1 EGO24599.1 - 0.069 12.5 5.2 0.14 11.5 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) BUD22 PF09073.5 EGO24599.1 - 0.35 9.8 13.7 0.52 9.3 9.5 1.2 1 0 0 1 1 1 0 BUD22 TEX19 PF15553.1 EGO24599.1 - 0.61 9.9 2.3 0.94 9.3 1.6 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 SDA1 PF05285.7 EGO24599.1 - 0.85 8.8 14.3 1.3 8.2 9.9 1.3 1 0 0 1 1 1 0 SDA1 DUF2040 PF09745.4 EGO24599.1 - 1.6 8.5 12.8 0.19 11.5 5.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) YqfQ PF14181.1 EGO24599.1 - 6 6.8 7.9 9.7 6.2 5.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein eIF3_subunit PF08597.5 EGO24599.1 - 6.7 6.1 18.6 0.14 11.6 8.2 1.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4614 PF15391.1 EGO24599.1 - 7.4 6.3 10.7 13 5.4 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) UBN2_3 PF14244.1 EGO24600.1 - 3.6e-06 26.6 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO24600.1 - 1.1e-05 24.7 0.1 2.1e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EGO24600.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO24602.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Rod-binding PF10135.4 EGO24603.1 - 0.017 15.1 0.1 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Rod binding protein zf-CCHC PF00098.18 EGO24604.1 - 4e-05 23.3 2.2 7.7e-05 22.4 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO24604.1 - 0.021 14.4 1.4 0.04 13.5 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Homoserine_dh PF00742.14 EGO24605.1 - 0.11 12.2 0.4 0.24 11.0 0.1 1.3 1 1 0 1 1 1 0 Homoserine dehydrogenase DUF4661 PF15576.1 EGO24605.1 - 0.33 10.5 3.6 0.38 10.3 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Retrotrans_gag PF03732.12 EGO24606.1 - 3.8e-07 30.0 3.2 5e-07 29.6 0.0 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein UBX PF00789.15 EGO24607.1 - 1.7e-12 47.1 0.9 5.3e-12 45.6 0.2 2.0 2 0 0 2 2 2 1 UBX domain ThiF PF00899.16 EGO24608.1 - 5.8e-43 145.9 0.2 1.1e-42 145.0 0.1 1.5 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EGO24608.1 - 1.2e-24 85.7 0.1 2.7e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EGO24608.1 - 5.7e-09 36.3 0.0 1.3e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EGO24608.1 - 1.6e-05 25.0 0.2 0.00012 22.1 0.1 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO24608.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EGO24608.1 - 0.17 10.8 0.1 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain APC10 PF03256.11 EGO24609.1 - 1.6e-47 161.5 0.0 2e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EGO24609.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 F5/8 type C domain PHD PF00628.24 EGO24610.1 - 1.9e-06 27.4 12.0 3.4e-06 26.6 8.3 1.5 1 0 0 1 1 1 1 PHD-finger Alba PF01918.16 EGO24611.1 - 0.00051 19.5 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 Alba PITH PF06201.8 EGO24612.1 - 3.3e-37 127.6 0.0 4.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain YchF-GTPase_C PF06071.8 EGO24615.1 - 3.1e-35 119.8 0.0 8.1e-35 118.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGO24615.1 - 2.9e-15 56.2 0.0 1.2e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO24615.1 - 6.1e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EGO24615.1 - 0.034 14.9 0.0 0.1 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain BetaGal_dom3 PF13363.1 EGO24615.1 - 0.066 12.6 0.2 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 RPAP1_N PF08621.5 EGO24615.1 - 0.15 11.6 0.8 0.27 10.8 0.6 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal FliJ PF02050.11 EGO24617.1 - 0.00068 19.6 11.6 0.01 15.8 0.3 2.4 2 1 0 2 2 2 2 Flagellar FliJ protein NPV_P10 PF05531.7 EGO24617.1 - 0.0047 17.1 4.2 0.42 10.8 0.5 2.9 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EGO24617.1 - 0.065 13.0 5.0 2 8.2 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EGO24617.1 - 0.12 10.8 4.9 0.099 11.0 0.2 2.0 1 1 1 2 2 2 0 AAA domain Prominin PF05478.6 EGO24617.1 - 0.13 9.8 3.1 0.15 9.6 2.2 1.2 1 0 0 1 1 1 0 Prominin DASH_Duo1 PF08651.5 EGO24617.1 - 0.16 11.5 5.7 3.4 7.2 0.0 3.6 4 0 0 4 4 4 0 DASH complex subunit Duo1 Filo_VP35 PF02097.10 EGO24617.1 - 0.25 10.5 2.5 0.98 8.5 0.2 2.2 1 1 1 2 2 2 0 Filoviridae VP35 DUF342 PF03961.8 EGO24617.1 - 0.28 9.5 7.8 2.4 6.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 EGO24617.1 - 0.75 8.1 6.4 0.1 10.9 0.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain End3 PF12761.2 EGO24617.1 - 1.3 8.6 14.5 0.16 11.6 3.8 2.5 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF4446 PF14584.1 EGO24617.1 - 1.9 8.3 9.7 5.9 6.7 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Syntaxin-6_N PF09177.6 EGO24617.1 - 1.9 8.9 5.4 6.3 7.2 0.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Nnf1 PF03980.9 EGO24617.1 - 2.7 8.0 10.0 0.4 10.6 3.1 2.2 1 1 1 2 2 2 0 Nnf1 Prefoldin_2 PF01920.15 EGO24617.1 - 7.3 6.4 15.2 6 6.6 4.4 3.7 3 1 0 3 3 3 0 Prefoldin subunit CENP-Q PF13094.1 EGO24617.1 - 8.2 6.4 12.4 7.8 6.5 0.4 2.6 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 EGO24617.1 - 8.3 6.8 13.9 7.1 7.0 0.6 3.5 4 0 0 4 4 3 0 SlyX Voldacs PF03517.8 EGO24618.1 - 2.2e-30 105.2 0.2 2.2e-30 105.2 0.1 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling SH3_1 PF00018.23 EGO24619.1 - 1.2e-09 37.3 0.1 1.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO24619.1 - 8.8e-09 34.8 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO24619.1 - 5e-08 32.3 0.0 7.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Mito_fiss_reg PF05308.6 EGO24621.1 - 0.025 13.9 6.6 0.027 13.8 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MARVEL PF01284.18 EGO24622.1 - 1.1e-10 41.5 12.3 1.6e-10 40.9 8.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain NUDIX PF00293.23 EGO24623.1 - 1.3e-14 53.9 0.0 3.9e-14 52.4 0.0 1.7 1 1 1 2 2 2 1 NUDIX domain APG6 PF04111.7 EGO24624.1 - 0.029 13.4 7.0 0.054 12.5 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EGO24624.1 - 1.2 8.6 7.7 0.32 10.5 2.6 1.8 2 0 0 2 2 2 0 IncA protein Aminotran_3 PF00202.16 EGO24625.1 - 1.4e-41 142.5 0.0 5.8e-40 137.1 0.0 3.0 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EGO24625.1 - 5.2e-28 98.0 0.0 9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PI3Ka PF00613.15 EGO24626.1 - 7.5e-54 181.7 0.1 1.3e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EGO24626.1 - 1.9e-38 131.4 0.0 3.7e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.22 EGO24626.1 - 7.3e-37 127.0 0.0 2.4e-35 122.1 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase IlvN PF07991.7 EGO24627.1 - 1.3e-45 154.6 0.0 2.5e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGO24627.1 - 7.3e-43 145.9 0.0 1.2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Cauli_VI PF01693.11 EGO24629.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Alpha_kinase PF02816.13 EGO24631.1 - 1.1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family p450 PF00067.17 EGO24632.1 - 3.6e-07 29.0 0.0 4.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YopE_N PF09020.5 EGO24632.1 - 0.08 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 YopE, N terminal p450 PF00067.17 EGO24634.1 - 3.9e-73 246.5 0.0 4.4e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAP_N PF01213.14 EGO24636.1 - 0.72 9.0 2.8 0.55 9.4 1.2 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tcp11 PF05794.8 EGO24637.1 - 0.053 12.2 0.2 0.085 11.5 0.2 1.3 1 0 0 1 1 1 0 T-complex protein 11 p450 PF00067.17 EGO24638.1 - 5e-60 203.3 0.0 6.1e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aconitase PF00330.15 EGO24639.1 - 3.6e-72 243.3 0.6 1.5e-42 145.7 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO24639.1 - 3.2e-20 72.5 0.0 6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EGO24639.1 - 0.051 12.9 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus Telomere_Sde2 PF13019.1 EGO24640.1 - 9.9e-52 174.8 0.0 4.2e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 Telomere stability and silencing GTSE1_N PF15259.1 EGO24640.1 - 1.4 8.8 7.6 0.26 11.2 1.9 1.9 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 DUF572 PF04502.8 EGO24640.1 - 9.6 5.3 12.3 12 4.9 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1295 PF06966.7 EGO24641.1 - 8.1e-36 123.4 3.4 4.2e-35 121.1 2.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) p450 PF00067.17 EGO24642.1 - 2.1e-46 158.4 0.0 2.1e-31 108.9 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 HSP20 PF00011.16 EGO24643.1 - 1e-23 83.0 0.1 8.1e-23 80.2 0.0 1.9 1 1 1 2 2 2 2 Hsp20/alpha crystallin family DUF4097 PF13349.1 EGO24643.1 - 0.0051 16.3 0.0 0.0068 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) VLPT PF07122.6 EGO24643.1 - 0.06 13.0 0.1 0.23 11.1 0.1 2.1 1 1 0 1 1 1 0 Variable length PCR target protein (VLPT) CS PF04969.11 EGO24643.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 CS domain BON PF04972.12 EGO24643.1 - 0.14 11.8 0.0 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 BON domain p450 PF00067.17 EGO24644.1 - 1.1e-18 67.0 0.0 1.2e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO24645.1 - 1.1e-47 162.6 0.0 1.4e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CIA30 PF08547.7 EGO24646.1 - 0.047 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Ras PF00071.17 EGO24647.1 - 3.4e-57 192.3 0.0 4e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO24647.1 - 5.2e-19 68.8 0.0 7.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO24647.1 - 1.2e-06 27.8 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO24647.1 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGO24647.1 - 0.017 14.3 0.0 0.034 13.4 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGO24647.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 EGO24648.1 - 3.4e-58 195.5 0.2 4e-58 195.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO24648.1 - 6.4e-20 71.8 0.0 9.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO24648.1 - 7.1e-09 35.1 0.0 8.6e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO24648.1 - 1.6e-06 27.6 0.1 3.3e-06 26.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO24648.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO24648.1 - 0.022 14.0 0.1 0.059 12.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ser_hydrolase PF06821.8 EGO24648.1 - 0.084 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase IstB_IS21 PF01695.12 EGO24648.1 - 0.12 11.7 0.2 0.97 8.8 0.1 2.3 2 1 1 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EGO24648.1 - 0.15 11.6 2.2 1 8.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pex26 PF07163.7 EGO24649.1 - 3.5 6.4 5.1 3.1 6.6 0.4 2.3 2 0 0 2 2 2 0 Pex26 protein IMS PF00817.15 EGO24650.1 - 9.8e-43 145.5 0.0 2e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO24650.1 - 1.3e-14 54.2 0.0 2.9e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGO24650.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PH PF00169.24 EGO24651.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 PH domain Pyr_redox_2 PF07992.9 EGO24652.1 - 5.2e-32 111.3 1.9 8.2e-32 110.7 1.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EGO24652.1 - 1.1e-16 60.1 0.0 3.9e-16 58.4 0.1 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGO24652.1 - 4.6e-10 39.9 0.2 3.6e-05 23.9 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO24652.1 - 1.5e-09 38.0 0.5 1.5e-09 38.0 0.3 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EGO24652.1 - 1.8e-07 31.3 0.0 4.7e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 EGO24652.1 - 4.2e-07 29.6 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DAO PF01266.19 EGO24652.1 - 9e-06 24.8 0.4 0.085 11.7 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGO24652.1 - 0.0009 18.2 0.1 0.63 8.9 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EGO24652.1 - 0.015 14.4 0.2 0.028 13.5 0.0 1.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EGO24652.1 - 0.13 12.5 0.4 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Metallophos PF00149.23 EGO24653.1 - 2.3e-07 30.3 1.7 4.7e-07 29.3 1.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO24653.1 - 1.9e-06 27.8 0.0 4.7e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThuA PF06283.6 EGO24655.1 - 6.3e-56 189.4 0.1 7.7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation Pex14_N PF04695.8 EGO24655.1 - 0.25 11.3 2.3 19 5.2 0.0 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DnaJ PF00226.26 EGO24656.1 - 3.6e-22 77.8 0.9 5.9e-22 77.1 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO24656.1 - 4e-21 74.7 0.7 1.2e-19 69.9 0.1 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGO24656.1 - 1.3e-11 44.3 18.8 2.3e-11 43.5 13.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGO24656.1 - 0.5 10.0 12.4 1.3 8.7 2.9 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EGO24656.1 - 3.5 8.0 10.8 0.46 10.8 4.4 1.9 2 1 0 2 2 2 0 Cytochrome c3 Nol1_Nop2_Fmu PF01189.12 EGO24657.1 - 2.3e-22 79.7 0.0 4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Cons_hypoth95 PF03602.10 EGO24657.1 - 0.0057 16.0 0.6 0.051 12.9 0.0 2.4 2 1 1 3 3 3 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EGO24657.1 - 0.018 14.6 0.0 0.058 12.9 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain zf-CCHC PF00098.18 EGO24658.1 - 1.3e-11 43.7 7.1 1.6e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EGO24658.1 - 1.2e-06 28.1 3.7 0.0031 17.2 1.1 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EGO24658.1 - 3.3e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EGO24658.1 - 0.00028 20.4 0.0 0.00071 19.1 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EGO24658.1 - 0.0005 19.6 4.6 0.36 10.5 0.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EGO24658.1 - 0.00083 18.9 6.3 0.28 10.8 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EGO24658.1 - 0.062 13.3 5.0 0.13 12.2 3.5 1.5 1 0 0 1 1 1 0 DnaJ central domain Mating_C PF12737.2 EGO24658.1 - 0.49 9.2 7.6 1.6 7.5 3.2 2.2 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 CCDC-167 PF15188.1 EGO24658.1 - 0.87 9.5 5.4 0.38 10.7 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Helicase_C_3 PF13625.1 EGO24659.1 - 1.4e-24 86.2 0.0 6.7e-24 84.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO24659.1 - 1.7e-14 54.0 0.0 3.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGO24659.1 - 5.6e-13 48.3 0.1 9e-13 47.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO24659.1 - 0.00049 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SBP_bac_6 PF13343.1 EGO24659.1 - 0.057 12.7 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein bZIP_1 PF00170.16 EGO24660.1 - 6.4e-05 22.8 2.1 0.00011 22.0 1.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 EGO24660.1 - 0.004 15.4 29.4 0.0051 15.1 20.4 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 bZIP_2 PF07716.10 EGO24660.1 - 0.0068 16.1 1.7 0.014 15.1 1.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Shugoshin_N PF07558.6 EGO24660.1 - 0.11 12.2 0.4 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.1 EGO24660.1 - 0.12 12.0 0.2 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif UDG PF03167.14 EGO24661.1 - 1.3e-21 76.6 0.1 2.1e-12 46.7 0.0 2.7 3 0 0 3 3 3 2 Uracil DNA glycosylase superfamily Response_reg PF00072.19 EGO24662.1 - 1.1e-18 67.1 0.0 2.4e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EGO24662.1 - 3e-17 62.3 0.1 8.1e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGO24662.1 - 7.3e-13 48.3 0.2 2.2e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CTP_transf_1 PF01148.15 EGO24662.1 - 2.2e-05 24.2 8.1 2.2e-05 24.2 5.6 2.6 2 2 0 2 2 2 1 Cytidylyltransferase family GAF PF01590.21 EGO24662.1 - 0.00025 21.2 0.0 0.0036 17.4 0.0 2.7 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.1 EGO24662.1 - 0.00088 19.3 0.0 0.022 14.8 0.0 3.0 3 0 0 3 3 3 1 GAF domain VSP PF03302.8 EGO24662.1 - 1.5 7.4 0.9 2.2 6.8 0.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein HMGL-like PF00682.14 EGO24663.1 - 1.1e-70 238.0 0.5 1.8e-70 237.2 0.3 1.4 1 0 0 1 1 1 1 HMGL-like zf-HIT PF04438.11 EGO24664.1 - 5.1e-08 32.4 10.4 9.4e-08 31.5 7.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Cys_Met_Meta_PP PF01053.15 EGO24665.1 - 2.5e-127 424.3 0.0 3.3e-127 423.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EGO24665.1 - 5.4e-18 64.8 0.0 5.4e-18 64.8 0.0 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO24665.1 - 6.8e-06 26.2 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal DegT_DnrJ_EryC1 PF01041.12 EGO24665.1 - 5.9e-05 22.2 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EGO24665.1 - 0.00042 19.5 0.0 0.00084 18.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GalKase_gal_bdg PF10509.4 EGO24665.1 - 0.00044 19.4 0.0 0.00084 18.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.16 EGO24665.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.8 EGO24665.1 - 0.0018 17.0 0.0 0.01 14.5 0.0 1.9 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Met_gamma_lyase PF06838.6 EGO24665.1 - 0.008 14.5 0.0 0.021 13.1 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Terpene_synth_C PF03936.11 EGO24666.1 - 2.1e-10 40.3 0.3 3.4e-10 39.5 0.2 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.14 EGO24667.1 - 8.3e-36 121.4 0.2 1.6e-35 120.4 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EGO24667.1 - 1.4e-27 95.8 0.1 2.5e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EGO24667.1 - 0.00038 20.2 0.0 0.00059 19.6 0.0 1.4 1 1 0 1 1 1 1 Restriction endonuclease R3H PF01424.17 EGO24667.1 - 0.023 14.3 0.0 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 R3H domain WD40 PF00400.27 EGO24668.1 - 4e-14 51.8 2.8 0.0053 16.5 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGO24668.1 - 0.093 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region ECH PF00378.15 EGO24669.1 - 4.3e-21 75.1 0.0 5.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Urease_beta PF00699.15 EGO24670.1 - 0.025 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Urease beta subunit Pkinase PF00069.20 EGO24673.1 - 1.7e-56 191.2 0.0 2.5e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO24673.1 - 3.9e-19 68.7 0.0 1.1e-18 67.2 0.0 1.7 1 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EGO24673.1 - 0.034 13.4 0.1 0.084 12.2 0.1 1.7 1 0 0 1 1 1 0 RIO1 family MOZ_SAS PF01853.13 EGO24675.1 - 6.9e-75 250.4 0.0 1.1e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EGO24675.1 - 3.6e-07 29.7 11.1 6.8e-07 28.8 5.2 2.4 2 0 0 2 2 2 1 PHD-finger Plasmodium_Vir PF05795.6 EGO24675.1 - 0.84 8.7 2.7 1.8 7.6 1.8 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein p450 PF00067.17 EGO24676.1 - 1.9e-69 234.3 0.0 5.5e-69 232.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.1 EGO24677.1 - 9.7e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO24677.1 - 0.00013 22.4 0.0 0.0002 21.8 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO24677.1 - 0.00034 20.5 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EGO24678.1 - 0.0015 18.5 3.0 0.0017 18.3 0.0 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein p450 PF00067.17 EGO24679.1 - 1.4e-73 247.9 0.0 3.5e-73 246.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.12 EGO24680.1 - 2.3e-36 125.2 0.0 3.5e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO24680.1 - 2.5e-34 118.6 0.0 4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGO24680.1 - 0.00026 20.0 0.0 0.00042 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Viral_DNA_bi PF02236.12 EGO24680.1 - 0.025 14.7 0.0 0.066 13.3 0.0 1.7 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain RIO1 PF01163.17 EGO24680.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2531 PF10748.4 EGO24681.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) DSBA PF01323.15 EGO24683.1 - 1.9e-29 102.6 0.1 2.3e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGO24683.1 - 2.3e-06 27.7 2.3 3.1e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 EGO24683.1 - 0.016 14.9 0.2 0.073 12.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_5 PF13743.1 EGO24683.1 - 0.071 12.6 1.5 0.13 11.7 1.0 1.6 1 1 0 1 1 1 0 Thioredoxin Frag1 PF10277.4 EGO24684.1 - 3.5e-35 121.4 13.4 4.1e-35 121.2 9.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EI24 PF07264.6 EGO24684.1 - 0.75 9.1 17.2 0.21 10.9 9.3 2.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF2231 PF09990.4 EGO24684.1 - 1 9.7 6.2 0.13 12.6 1.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) GRIN_C PF15235.1 EGO24686.1 - 0.47 10.5 3.4 0.53 10.3 2.4 1.1 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus DXP_synthase_N PF13292.1 EGO24687.1 - 0.086 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase p450 PF00067.17 EGO24688.1 - 4.6e-71 239.7 0.0 1.3e-70 238.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 UBN2_2 PF14227.1 EGO24689.1 - 5.9e-08 32.2 0.3 8.7e-08 31.7 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO24689.1 - 9.8e-06 25.3 0.6 3e-05 23.7 0.4 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type NICE-3 PF07406.6 EGO24689.1 - 0.0025 17.3 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 NICE-3 protein UBN2_3 PF14244.1 EGO24689.1 - 0.0027 17.2 0.3 0.004 16.7 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Cullin_binding PF03556.10 EGO24689.1 - 0.061 13.4 0.7 0.089 12.9 0.5 1.4 1 1 0 1 1 1 0 Cullin binding gag-asp_proteas PF13975.1 EGO24691.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO24691.1 - 0.03 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EGO24692.1 - 0.00037 20.2 4.6 0.00037 20.2 3.2 2.3 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO24692.1 - 0.0025 17.5 3.6 0.0025 17.5 2.5 1.8 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO24692.1 - 0.09 12.8 0.6 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein adh_short PF00106.20 EGO24697.1 - 3.7e-21 75.7 0.3 4.8e-21 75.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO24697.1 - 7.1e-15 55.4 0.0 1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO24697.1 - 8.5e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO24697.1 - 8.6e-05 22.0 0.1 0.00014 21.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO24697.1 - 0.00031 19.7 0.0 0.00053 18.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO24697.1 - 0.014 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO24697.1 - 0.025 14.5 0.2 0.047 13.7 0.0 1.7 2 1 0 2 2 2 0 NADH(P)-binding p450 PF00067.17 EGO24698.1 - 2.9e-73 246.9 0.0 5.7e-73 246.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NACHT PF05729.7 EGO24700.1 - 9.8e-09 35.0 0.0 5.1e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO24700.1 - 0.00018 21.5 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EGO24700.1 - 0.0017 17.4 0.0 0.0049 15.8 0.0 1.8 1 1 1 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.1 EGO24700.1 - 0.015 15.4 0.0 0.055 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGO24700.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EGO24700.1 - 0.025 14.0 0.1 0.096 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGO24700.1 - 0.059 13.5 0.0 0.21 11.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGO24700.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EGO24700.1 - 0.087 11.6 0.0 0.55 9.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EGO24700.1 - 0.14 12.2 0.1 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EGO24700.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 NTPase AAA_30 PF13604.1 EGO24700.1 - 0.24 10.9 0.4 0.52 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EGO24705.1 - 7.1e-38 129.7 0.0 3.1e-37 127.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO24705.1 - 4.1e-19 68.2 0.1 8.1e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO24705.1 - 1.5e-11 44.4 0.1 5.7e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO24705.1 - 0.034 14.2 0.1 0.76 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO24705.1 - 0.034 13.8 0.2 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain MIP-T3 PF10243.4 EGO24705.1 - 0.12 10.8 18.1 0.16 10.3 12.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ABC_tran PF00005.22 EGO24706.1 - 1.1e-39 135.8 0.0 8e-28 97.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO24706.1 - 8.5e-31 107.3 25.5 3.4e-14 52.9 8.7 3.8 2 2 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGO24706.1 - 0.0038 16.5 0.0 0.13 11.4 0.0 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO24706.1 - 0.0044 17.0 1.4 1.4 8.8 1.1 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO24706.1 - 0.034 14.0 0.4 0.099 12.6 0.3 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase p450 PF00067.17 EGO24707.1 - 2.3e-62 211.0 0.1 5e-62 209.9 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 XFP_N PF09364.5 EGO24709.1 - 4.6e-153 509.2 0.0 5.9e-153 508.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EGO24709.1 - 3.9e-71 238.3 0.0 6.6e-71 237.5 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EGO24709.1 - 4.1e-65 219.0 0.0 7.2e-65 218.2 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EGO24709.1 - 0.00093 18.7 0.1 0.0025 17.3 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain p450 PF00067.17 EGO24710.1 - 2.1e-56 191.4 0.0 3.1e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO24711.1 - 5.1e-60 203.2 0.0 6.7e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGO24714.1 - 1.2e-18 67.2 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO24714.1 - 2.9e-06 26.5 0.0 4.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO24714.1 - 0.016 14.9 0.0 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DDE_1 PF03184.14 EGO24715.1 - 1.6e-25 89.5 0.0 3.4e-25 88.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HrpJ PF07201.6 EGO24717.1 - 0.017 15.1 0.3 0.022 14.7 0.2 1.3 1 0 0 1 1 1 0 HrpJ-like domain MOSC PF03473.12 EGO24718.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 MOSC domain MFS_1 PF07690.11 EGO24721.1 - 2e-10 39.9 24.3 2e-10 39.9 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO24723.1 - 5.6e-37 127.3 38.6 7.4e-23 80.8 8.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGO24723.1 - 2.1e-22 79.3 42.4 2.6e-15 56.0 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO24723.1 - 4.3e-06 25.3 23.0 0.00033 19.1 1.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein DSS1_SEM1 PF05160.8 EGO24724.1 - 4.9e-18 64.6 16.2 1.1e-17 63.4 10.7 1.9 1 1 0 1 1 1 1 DSS1/SEM1 family SIR2 PF02146.12 EGO24725.1 - 4.2e-28 98.2 0.0 4.8e-18 65.5 0.0 2.5 2 1 0 2 2 2 2 Sir2 family BmKX PF09132.5 EGO24725.1 - 0.0081 15.9 0.0 0.0081 15.9 0.0 2.3 3 0 0 3 3 3 1 BmKX TPP_enzyme_M PF00205.17 EGO24725.1 - 0.051 13.3 0.9 0.98 9.1 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Alpha-E PF04168.7 EGO24727.1 - 0.094 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. ADH_zinc_N PF00107.21 EGO24728.1 - 1.9e-27 95.3 0.6 2.8e-27 94.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO24728.1 - 3.3e-19 70.0 0.1 6.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO24728.1 - 4.9e-12 45.5 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 EGO24730.1 - 5e-32 108.6 3.9 4.6e-07 29.4 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EGO24730.1 - 0.0018 18.0 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ADH_zinc_N PF00107.21 EGO24731.1 - 1.7e-13 50.2 0.3 2.8e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO24731.1 - 1.8e-12 48.2 0.0 3.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO24731.1 - 2.6e-11 43.2 0.1 6.9e-09 35.4 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain FA_hydroxylase PF04116.8 EGO24732.1 - 2.8e-14 53.4 23.4 2.8e-14 53.4 16.3 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily eIF3_N PF09440.5 EGO24733.1 - 5.6e-43 146.2 5.2 3.5e-42 143.7 2.6 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGO24733.1 - 7.3e-08 32.6 0.2 2.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain PARP_reg PF02877.9 EGO24733.1 - 0.08 12.6 0.2 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain Asp PF00026.18 EGO24734.1 - 2.8e-21 76.0 0.5 3.2e-21 75.8 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO24734.1 - 1.1e-06 28.6 1.1 1.8e-06 28.0 0.7 1.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Pex14_N PF04695.8 EGO24735.1 - 1.2e-22 80.4 6.2 1.9e-21 76.5 0.4 3.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.14 EGO24735.1 - 2e-05 22.6 0.1 2.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AIP3 PF03915.8 EGO24735.1 - 0.0012 17.7 3.7 0.0017 17.3 2.6 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 BicD PF09730.4 EGO24735.1 - 0.0042 15.5 6.4 0.0065 14.8 4.5 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TBPIP PF07106.8 EGO24735.1 - 0.0044 16.5 8.8 0.0066 16.0 6.1 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 EGO24735.1 - 0.0074 16.0 12.1 0.0094 15.7 7.1 1.8 2 0 0 2 2 2 1 Laminin Domain II Phlebovirus_NSM PF07246.6 EGO24735.1 - 0.0078 15.4 2.8 0.011 14.8 2.0 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M MCPsignal PF00015.16 EGO24735.1 - 0.0088 15.6 5.0 0.013 15.0 3.5 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Mt_ATP-synt_D PF05873.7 EGO24735.1 - 0.0094 15.6 4.7 0.01 15.5 2.6 1.5 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Mitofilin PF09731.4 EGO24735.1 - 0.0099 14.5 8.6 0.02 13.5 6.0 1.4 1 1 0 1 1 1 1 Mitochondrial inner membrane protein IncA PF04156.9 EGO24735.1 - 0.013 15.1 9.4 0.013 15.1 6.5 1.7 2 0 0 2 2 2 0 IncA protein ING PF12998.2 EGO24735.1 - 0.029 14.6 6.0 0.029 14.6 4.2 1.5 2 0 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding AAA_13 PF13166.1 EGO24735.1 - 0.05 12.0 6.9 0.069 11.6 4.8 1.1 1 0 0 1 1 1 0 AAA domain DUF3829 PF12889.2 EGO24735.1 - 0.055 12.6 2.3 0.085 12.0 1.3 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3829) NPV_P10 PF05531.7 EGO24735.1 - 0.067 13.4 11.5 0.24 11.6 0.9 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EGO24735.1 - 0.074 10.3 10.9 0.099 9.9 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.4 EGO24735.1 - 0.094 11.4 10.4 0.055 12.2 2.6 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HAUS-augmin3 PF14932.1 EGO24735.1 - 0.11 11.6 9.3 0.16 11.1 6.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Allexi_40kDa PF05549.6 EGO24735.1 - 0.12 11.6 1.8 0.26 10.5 1.3 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein APG6 PF04111.7 EGO24735.1 - 0.2 10.7 11.1 0.3 10.1 7.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1759 PF03564.10 EGO24735.1 - 0.23 11.2 2.4 0.56 10.0 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) HAUS6_N PF14661.1 EGO24735.1 - 0.27 10.5 4.2 0.4 10.0 2.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2450 PF10475.4 EGO24735.1 - 0.29 9.9 5.2 0.42 9.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Spectrin PF00435.16 EGO24735.1 - 0.32 11.3 9.1 0.12 12.6 3.6 2.0 1 1 1 2 2 2 0 Spectrin repeat Fib_alpha PF08702.5 EGO24735.1 - 0.32 11.0 7.5 0.61 10.2 5.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2317 PF10079.4 EGO24735.1 - 0.35 9.4 8.3 0.49 8.9 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Prominin PF05478.6 EGO24735.1 - 0.37 8.2 2.4 0.52 7.7 1.6 1.1 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.7 EGO24735.1 - 0.38 10.5 3.8 0.22 11.3 1.1 1.7 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.3 EGO24735.1 - 0.53 8.8 2.8 0.35 9.4 0.6 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF2968 PF11180.3 EGO24735.1 - 0.56 9.5 10.9 0.97 8.7 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1664 PF07889.7 EGO24735.1 - 0.91 9.3 11.2 1.6 8.5 1.1 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EGO24735.1 - 0.92 8.3 7.9 1.3 7.8 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_p24 PF05073.7 EGO24735.1 - 1.1 8.7 5.1 1.7 8.1 2.2 2.0 2 1 0 2 2 2 0 Baculovirus P24 capsid protein L31 PF09784.4 EGO24735.1 - 1.5 8.9 5.9 2.3 8.3 3.4 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 Mnd1 PF03962.10 EGO24735.1 - 2.1 7.9 10.9 3.3 7.3 7.5 1.2 1 0 0 1 1 1 0 Mnd1 family HisKA_3 PF07730.8 EGO24735.1 - 2.2 8.6 6.7 1.9 8.9 1.3 2.6 1 1 1 2 2 2 0 Histidine kinase Spc7 PF08317.6 EGO24735.1 - 3 6.4 12.5 6.9 5.2 8.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL25 PF01499.11 EGO24735.1 - 3.2 5.9 6.2 4.2 5.5 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Apolipoprotein PF01442.13 EGO24735.1 - 3.6 7.0 16.4 1 8.8 9.0 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2664 PF10867.3 EGO24735.1 - 4.2 8.0 11.0 5.5 7.6 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Metal_resist PF13801.1 EGO24735.1 - 5.5 6.9 8.7 14 5.6 4.9 2.2 1 1 2 3 3 3 0 Heavy-metal resistance YkuI_C PF10388.4 EGO24735.1 - 8.7 5.9 7.6 11 5.6 0.0 2.7 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain BRO1 PF03097.13 EGO24737.1 - 8.5e-89 297.9 0.4 1.6e-88 297.0 0.2 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGO24737.1 - 4.5e-68 229.3 14.5 4.5e-68 229.3 10.1 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF349 PF03993.7 EGO24737.1 - 4.9 7.3 10.7 4.6 7.4 0.0 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF349) DUF3421 PF11901.3 EGO24738.1 - 5.5e-15 55.1 0.0 7.3e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) WLM PF08325.5 EGO24739.1 - 1.3e-51 175.0 0.1 6e-51 172.9 0.0 2.1 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 EGO24739.1 - 1.3e-05 25.0 1.9 1.6e-05 24.7 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGO24739.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EGO24739.1 - 0.078 13.0 0.6 0.17 11.9 0.4 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily PQ-loop PF04193.9 EGO24740.1 - 1.8e-20 72.2 8.0 4.9e-10 38.8 0.2 2.7 3 0 0 3 3 3 2 PQ loop repeat ABC2_membrane_4 PF12730.2 EGO24740.1 - 0.051 12.7 5.2 0.014 14.6 1.2 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein TraX PF05857.6 EGO24740.1 - 0.099 12.2 3.2 1.6 8.3 1.7 2.2 1 1 0 1 1 1 0 TraX protein Cytochrom_B_N_2 PF13631.1 EGO24740.1 - 0.75 9.5 3.9 1.3 8.7 0.7 2.6 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB NMN_transporter PF04973.7 EGO24740.1 - 0.79 9.1 6.6 0.18 11.2 1.4 2.1 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter TauE PF01925.14 EGO24740.1 - 1.8 7.9 11.3 17 4.7 8.3 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Acetate_kinase PF00871.12 EGO24742.1 - 1.2e-95 320.3 0.1 3e-95 319.0 0.1 1.6 1 1 0 1 1 1 1 Acetokinase family p450 PF00067.17 EGO24743.1 - 3e-47 161.2 0.0 3.5e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO24744.1 - 0.029 12.8 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 DUF2428 PF10350.4 EGO24744.1 - 0.059 12.3 0.0 0.064 12.2 0.0 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) p450 PF00067.17 EGO24745.1 - 6.6e-76 255.6 0.0 7.9e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 EGO24746.1 - 9.9e-182 605.3 2.5 4.5e-92 309.4 0.0 2.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO24746.1 - 1e-17 64.4 5.8 9.9e-09 35.0 0.3 3.2 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO24746.1 - 4e-09 36.0 1.1 0.00049 19.3 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO24746.1 - 1e-06 28.5 3.3 0.0082 15.9 0.3 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2424 PF10340.4 EGO24746.1 - 0.1 11.2 0.1 18 3.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2424) Arv1 PF04161.8 EGO24747.1 - 9.4e-30 104.0 0.0 1.4e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family DUF410 PF04190.8 EGO24748.1 - 1.3e-32 113.4 0.0 1.6e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HSBP1 PF06825.7 EGO24749.1 - 2.2e-17 62.3 1.1 2.8e-17 62.0 0.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.7 EGO24749.1 - 0.026 14.3 0.2 0.033 14.0 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 EGO24749.1 - 0.066 12.5 0.2 0.67 9.3 0.1 2.0 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4164 PF13747.1 EGO24749.1 - 0.12 12.5 0.2 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 EGO24749.1 - 0.13 12.5 0.4 0.2 11.9 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Terpene_synth_C PF03936.11 EGO24750.1 - 2.8e-15 56.2 0.1 1.1e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Ank PF00023.25 EGO24751.1 - 2.9e-19 67.8 0.2 3.3e-06 26.6 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGO24751.1 - 6.5e-17 61.6 0.1 2.3e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO24751.1 - 2.5e-14 51.9 0.0 6e-05 22.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO24751.1 - 5.3e-13 49.0 0.1 3.9e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO24751.1 - 6.1e-12 45.3 0.3 0.00015 21.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) rve PF00665.21 EGO24755.1 - 6.1e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EGO24755.1 - 0.059 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease rve_3 PF13683.1 EGO24755.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Tfb2 PF03849.9 EGO24758.1 - 3e-132 440.6 0.1 3.6e-132 440.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGO24758.1 - 0.00099 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Terpene_synth_C PF03936.11 EGO24760.1 - 1.3e-20 73.7 0.0 1.8e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.1 EGO24760.1 - 0.07 12.9 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal Aldo_ket_red PF00248.16 EGO24762.1 - 4.9e-48 163.3 0.0 6.2e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TRH PF05438.7 EGO24767.1 - 0.031 13.6 0.0 0.033 13.5 0.0 1.0 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Nfu_N PF08712.6 EGO24767.1 - 0.055 13.0 0.2 0.079 12.5 0.2 1.2 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Sugar_tr PF00083.19 EGO24769.1 - 8.4e-107 357.5 29.7 9.6e-107 357.3 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO24769.1 - 4e-21 75.1 37.6 4e-21 75.1 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WBS28 PF15164.1 EGO24771.1 - 0.0049 15.9 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF4618 PF15397.1 EGO24773.1 - 0.0014 17.9 0.1 0.033 13.5 0.0 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EGO24773.1 - 0.01 15.6 1.2 0.13 12.0 0.8 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EGO24773.1 - 0.012 15.7 0.9 0.038 14.1 0.6 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1395 PF07160.7 EGO24773.1 - 0.079 12.4 0.5 0.37 10.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Prefoldin_2 PF01920.15 EGO24773.1 - 0.088 12.5 0.0 1.9 8.3 0.0 2.4 1 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 EGO24773.1 - 0.091 12.5 2.6 2.3 8.0 1.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EGO24773.1 - 0.11 11.6 2.2 0.27 10.3 1.5 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EGO24773.1 - 0.11 12.7 3.1 5.5 7.3 0.1 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein PX PF00787.19 EGO24777.1 - 0.00014 21.6 0.1 0.0015 18.3 0.1 2.3 1 1 0 1 1 1 1 PX domain DUF2396 PF09654.5 EGO24777.1 - 0.087 12.7 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) Herpes_capsid PF06112.6 EGO24777.1 - 0.96 9.4 8.4 0.19 11.7 2.8 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PB1 PF00564.19 EGO24778.1 - 0.021 14.4 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Actin PF00022.14 EGO24779.1 - 4.6e-47 160.2 0.0 5e-46 156.8 0.0 2.4 1 1 0 1 1 1 1 Actin Filaggrin PF03516.8 EGO24779.1 - 0.78 10.2 7.1 0.43 11.0 1.4 2.8 3 0 0 3 3 3 0 Filaggrin PNK3P PF08645.6 EGO24781.1 - 2.5e-45 153.7 0.0 4.5e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EGO24781.1 - 2.1e-20 73.0 0.0 3.4e-19 69.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain HAD_2 PF13419.1 EGO24781.1 - 0.028 14.6 0.0 0.61 10.2 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase KTI12 PF08433.5 EGO24781.1 - 0.031 13.4 0.6 6.4 5.9 0.0 2.4 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EGO24781.1 - 0.049 12.7 0.0 1.2 8.2 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin LNS2 PF08235.8 EGO24781.1 - 0.059 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) MFS_1 PF07690.11 EGO24783.1 - 1.7e-29 102.6 19.0 1.7e-29 102.6 13.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO24783.1 - 1.6e-08 33.5 0.7 1.6e-08 33.5 0.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGO24784.1 - 6.2e-34 117.2 16.8 9.3e-34 116.6 11.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO24784.1 - 6.1e-05 21.7 3.3 6.1e-05 21.7 2.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGO24784.1 - 0.00061 18.1 0.6 0.0011 17.3 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM18 PF14770.1 EGO24784.1 - 0.016 14.7 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 18 FixQ PF05545.6 EGO24785.1 - 0.37 10.4 3.1 0.78 9.4 2.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Fer4_13 PF13370.1 EGO24788.1 - 0.04 14.3 1.2 0.14 12.5 0.8 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain ENT PF03735.9 EGO24788.1 - 0.11 12.1 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 ENT domain DUF2410 PF10307.4 EGO24788.1 - 0.17 11.2 1.6 0.3 10.4 1.1 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) AbiH PF14253.1 EGO24788.1 - 0.27 10.8 1.4 0.91 9.0 1.0 1.8 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH TraF_2 PF13729.1 EGO24789.1 - 0.022 13.6 0.3 0.029 13.1 0.2 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Retrotrans_gag PF03732.12 EGO24789.1 - 0.037 14.0 0.2 0.079 13.0 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein p450 PF00067.17 EGO24791.1 - 1e-69 235.2 0.0 1.3e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Svf1 PF08622.5 EGO24792.1 - 4.7e-90 301.8 0.0 5.3e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Peptidase_M48 PF01435.13 EGO24794.1 - 4.1e-16 59.2 0.0 6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF563 PF04577.9 EGO24794.1 - 0.15 11.9 0.1 1.5 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF563) AA_permease_2 PF13520.1 EGO24795.1 - 1.6e-62 211.4 39.3 2e-62 211.1 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2839 PF10999.3 EGO24795.1 - 4.2 7.4 0.0 4.2 7.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2839) TPR_16 PF13432.1 EGO24796.1 - 2.4e-10 40.8 5.1 0.0012 19.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24796.1 - 2e-09 37.6 7.7 9.5e-05 22.6 0.3 4.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO24796.1 - 6.4e-09 35.0 2.6 1 9.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO24796.1 - 4.8e-08 32.8 0.5 0.15 11.9 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO24796.1 - 5.7e-08 32.2 0.7 0.0096 15.5 0.0 4.0 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EGO24796.1 - 4.1e-07 29.3 0.1 6.6 6.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO24796.1 - 9.3e-07 28.5 0.0 0.019 15.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO24796.1 - 1e-06 28.7 12.0 0.32 11.7 0.0 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO24796.1 - 0.00064 19.7 0.0 0.85 9.7 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGO24796.1 - 0.0024 17.5 0.0 5.6 6.9 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO24796.1 - 0.0041 16.8 3.2 15 5.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO24796.1 - 0.063 13.7 3.3 0.23 11.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO24796.1 - 0.27 11.7 3.2 33 5.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PfkB PF00294.19 EGO24797.1 - 4.9e-07 29.1 0.2 0.02 14.0 0.3 3.5 3 1 0 3 3 3 2 pfkB family carbohydrate kinase PARP PF00644.15 EGO24799.1 - 1.1e-12 47.8 0.2 2.3e-09 36.9 0.0 2.9 1 1 2 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EGO24800.1 - 1.5e-12 47.3 0.5 1.1e-09 38.0 0.0 2.9 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF155 PF02582.9 EGO24802.1 - 3e-41 141.2 0.0 4.5e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mesothelin PF06060.7 EGO24802.1 - 0.11 10.5 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) NADHdh_A3 PF14987.1 EGO24803.1 - 0.0069 16.2 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Ank_2 PF12796.2 EGO24805.1 - 0.0076 16.5 0.0 0.01 16.1 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO24805.1 - 0.0094 15.7 0.0 2.3 8.1 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EGO24805.1 - 0.0095 16.1 0.1 0.15 12.3 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO24805.1 - 0.021 15.3 0.1 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF1654 PF07867.6 EGO24805.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) p450 PF00067.17 EGO24806.1 - 7.2e-64 215.9 0.0 1.1e-63 215.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Clostridium_P47 PF06597.6 EGO24807.1 - 0.0057 15.2 2.2 0.011 14.3 1.5 1.5 1 1 0 1 1 1 1 Clostridium P-47 protein ADH_zinc_N PF00107.21 EGO24808.1 - 3e-21 75.3 0.0 5.1e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO24808.1 - 1.7e-08 35.4 0.0 3.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EGO24808.1 - 0.076 12.5 0.3 0.13 11.7 0.1 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MIP PF00230.15 EGO24809.1 - 3.2e-29 102.0 5.2 4.5e-29 101.5 3.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF819 PF05684.7 EGO24809.1 - 0.0059 15.4 0.8 0.015 14.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF819) PsbJ PF01788.12 EGO24809.1 - 1 8.9 7.0 5.1 6.7 0.5 3.0 2 0 0 2 2 2 0 PsbJ Mad3_BUB1_I PF08311.7 EGO24812.1 - 7.1e-31 106.6 0.4 1.2e-30 105.8 0.3 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EGO24812.1 - 2.1e-16 59.8 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO24812.1 - 2.5e-06 26.7 0.0 4.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EGO24812.1 - 0.0018 18.1 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Sigma70_ner PF04546.8 EGO24812.1 - 1.8 8.1 7.4 0.84 9.2 0.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4634 PF15465.1 EGO24816.1 - 0.017 15.2 0.4 0.024 14.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) FANCI_S2 PF14676.1 EGO24818.1 - 0.045 13.6 0.1 0.071 13.0 0.1 1.4 1 1 0 1 1 1 0 FANCI solenoid 2 RhoGEF PF00621.15 EGO24819.1 - 2e-34 119.0 0.8 3e-34 118.4 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EGO24819.1 - 1.3e-29 103.5 0.0 1.8e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EGO24819.1 - 9.2e-14 51.5 0.0 2.4e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGO24819.1 - 2.2e-05 24.5 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PH domain WD40 PF00400.27 EGO24820.1 - 1.2e-50 167.6 17.3 2e-10 40.1 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EGO24820.1 - 0.0036 16.7 3.8 0.18 11.2 0.1 3.1 1 1 1 2 2 2 2 PQQ-like domain DUF4613 PF15390.1 EGO24820.1 - 0.051 11.7 0.0 0.074 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Nup160 PF11715.3 EGO24820.1 - 0.29 9.2 1.0 4.4 5.3 0.2 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Thioredoxin PF00085.15 EGO24821.1 - 2.7e-59 197.2 0.0 1.3e-28 98.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EGO24821.1 - 4.5e-19 68.6 0.4 5.4e-08 33.0 0.0 3.0 2 2 0 2 2 2 2 Thioredoxin-like domain ERp29 PF07749.7 EGO24821.1 - 1.3e-18 67.4 0.3 3.1e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 EGO24821.1 - 2.4e-13 49.8 0.0 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGO24821.1 - 3.4e-13 49.5 0.1 0.00014 21.9 0.0 3.5 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EGO24821.1 - 3e-07 30.1 0.1 0.027 14.1 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EGO24821.1 - 6.5e-07 28.9 0.1 0.017 14.6 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EGO24821.1 - 0.0028 17.2 0.8 2.3 7.7 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_4 PF13462.1 EGO24821.1 - 0.003 17.6 0.7 1.5 8.7 0.0 3.4 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.1 EGO24821.1 - 0.0054 16.5 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.19 EGO24821.1 - 0.014 15.3 0.7 1.1 9.3 0.0 2.9 2 1 0 2 2 2 0 Glutaredoxin TraF PF13728.1 EGO24821.1 - 0.027 13.9 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.6 EGO24821.1 - 0.066 13.1 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Exo_endo_phos PF03372.18 EGO24822.1 - 5.4e-10 39.6 0.1 7.1e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Macoilin PF09726.4 EGO24823.1 - 7.8 4.6 5.8 9 4.4 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Sugar_tr PF00083.19 EGO24824.1 - 8.7e-74 248.7 20.2 1.1e-73 248.4 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO24824.1 - 6.8e-29 100.6 33.6 1.3e-22 79.9 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO24824.1 - 3.3e-08 32.3 23.1 6e-07 28.2 0.8 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EGO24824.1 - 0.0028 15.9 8.0 0.0063 14.7 2.7 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Alpha-amylase PF00128.19 EGO24825.1 - 4.6e-28 98.5 0.0 2.2e-27 96.3 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGO24825.1 - 2.8e-05 22.1 0.2 0.003 15.4 0.0 3.1 3 1 0 3 3 3 3 Glycosyl hydrolase family 70 Totivirus_coat PF05518.6 EGO24826.1 - 2.2 6.0 5.2 2.7 5.6 3.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Acetyltransf_3 PF13302.1 EGO24827.1 - 2.2e-11 44.1 0.0 2.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO24827.1 - 1.5e-05 24.9 0.0 3.3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_31 PF13847.1 EGO24828.1 - 1.1e-28 99.7 0.0 1.3e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO24828.1 - 9.7e-26 90.0 0.0 1.6e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO24828.1 - 7.4e-19 68.0 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO24828.1 - 3.5e-18 65.5 0.0 4.5e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGO24828.1 - 1.8e-17 63.5 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO24828.1 - 2.3e-17 63.5 0.0 3.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO24828.1 - 2.1e-16 60.0 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO24828.1 - 6.9e-12 45.3 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGO24828.1 - 4.5e-11 42.8 0.1 1.3e-10 41.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO24828.1 - 1.9e-07 30.6 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EGO24828.1 - 2.2e-07 30.4 0.0 3.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EGO24828.1 - 2.6e-06 26.6 0.0 4.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EGO24828.1 - 2.3e-05 23.5 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 EGO24828.1 - 0.00018 20.9 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_29 PF03141.11 EGO24828.1 - 0.00043 18.7 0.0 0.00066 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 EGO24828.1 - 0.0011 17.7 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) V_cholerae_RfbT PF05575.6 EGO24828.1 - 0.0023 17.0 0.0 0.18 10.7 0.0 2.1 1 1 1 2 2 2 1 Vibrio cholerae RfbT protein DREV PF05219.7 EGO24828.1 - 0.0042 16.0 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 EGO24828.1 - 0.0062 15.6 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EGO24828.1 - 0.0062 16.2 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGO24828.1 - 0.032 13.3 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.13 EGO24828.1 - 0.071 12.2 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EGO24828.1 - 0.071 12.2 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3759 PF12585.3 EGO24829.1 - 1.7e-32 111.1 9.1 2e-32 110.9 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF1310 PF07006.6 EGO24829.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) RNase_HII PF01351.13 EGO24830.1 - 1.1e-46 158.9 0.0 2.6e-46 157.7 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII p450 PF00067.17 EGO24831.1 - 5.5e-72 242.7 0.0 6.9e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO24832.1 - 1.8e-79 267.4 0.0 2e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EGO24836.1 - 4.7e-08 32.6 0.7 1.3e-07 31.2 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO24836.1 - 4.2e-05 23.0 0.1 0.00014 21.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain Xpo1 PF08389.7 EGO24837.1 - 1.1e-15 57.8 5.9 2.1e-15 56.9 0.0 4.3 4 2 1 5 5 5 1 Exportin 1-like protein HEAT PF02985.17 EGO24837.1 - 0.0095 15.9 2.2 1.7 8.9 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat MIT PF04212.13 EGO24837.1 - 0.013 15.3 0.2 0.038 13.8 0.1 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Cullin PF00888.17 EGO24838.1 - 2.9e-157 524.7 0.0 4e-157 524.2 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGO24838.1 - 3.1e-28 97.3 2.9 5.1e-28 96.7 1.4 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain DnaJ PF00226.26 EGO24839.1 - 2.6e-24 84.6 3.3 4.2e-24 84.0 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO24839.1 - 5.2e-20 71.1 0.0 7.8e-16 57.7 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGO24839.1 - 5.3e-16 58.4 16.4 8.6e-16 57.7 11.4 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGO24839.1 - 0.00014 21.5 1.5 0.15 11.7 0.0 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EGO24839.1 - 0.09 13.0 7.3 1.1 9.6 0.1 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.1 EGO24839.1 - 0.49 10.2 4.7 1.1 9.0 0.3 2.5 2 0 0 2 2 2 0 Zinc-ribbon PADR1 PF08063.7 EGO24839.1 - 1.9 7.9 9.1 5 6.6 1.2 2.8 2 1 0 2 2 2 0 PADR1 (NUC008) domain A2L_zn_ribbon PF08792.5 EGO24839.1 - 8.9 5.9 12.9 5.6 6.5 0.3 3.7 3 1 1 4 4 4 0 A2L zinc ribbon domain Mito_carr PF00153.22 EGO24840.1 - 5.7e-55 183.0 1.0 1.4e-20 72.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 EGO24846.1 - 2.9e-14 52.4 13.2 8.4e-05 22.6 0.3 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO24846.1 - 7.1e-12 44.7 11.7 0.00079 19.5 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO24846.1 - 2.3e-11 43.3 16.5 6.4e-06 26.2 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger double domain IBR PF01485.16 EGO24846.1 - 0.0012 18.6 6.2 0.071 13.0 2.4 2.1 1 1 1 2 2 2 2 IBR domain zf-TRAF PF02176.13 EGO24846.1 - 0.011 16.0 5.2 0.052 13.9 0.9 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 EGO24846.1 - 0.012 15.7 7.1 0.8 10.0 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGO24846.1 - 0.016 15.1 6.0 1.2 9.1 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO24846.1 - 0.025 14.7 7.9 2.8 8.1 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGO24846.1 - 0.26 10.9 0.1 0.26 10.9 0.1 3.4 4 1 0 4 4 4 0 zinc-finger of a C2HC-type Ogr_Delta PF04606.7 EGO24846.1 - 0.3 10.7 2.7 8.7 6.0 0.0 3.0 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger RRN7 PF11781.3 EGO24846.1 - 0.36 10.3 3.6 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-LYAR PF08790.6 EGO24846.1 - 0.82 9.4 6.5 3.6 7.3 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.5 EGO24846.1 - 1.4 8.8 7.8 9.3 6.2 0.2 3.3 2 1 2 4 4 4 0 Zinc ribbon domain zf-AN1 PF01428.11 EGO24846.1 - 3.8 7.4 10.2 3.6 7.5 2.9 3.1 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C4 PF00105.13 EGO24846.1 - 5.5 7.3 7.8 1.4 9.1 0.6 2.6 1 1 0 2 2 2 0 Zinc finger, C4 type (two domains) SMN PF06003.7 EGO24849.1 - 0.075 12.1 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4112 PF13430.1 EGO24851.1 - 1.1e-30 105.6 0.2 1.4e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) YbhQ PF11076.3 EGO24851.1 - 0.058 13.0 0.3 0.085 12.4 0.2 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Sporozoite_P67 PF05642.6 EGO24852.1 - 3.9 5.2 10.3 5.5 4.7 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FtsJ PF01728.14 EGO24854.1 - 6.1e-11 42.6 0.0 9.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EGO24854.1 - 0.088 13.3 0.1 0.22 12.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGO24855.1 - 3.2e-09 37.0 0.0 5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EGO24855.1 - 0.019 14.6 0.1 0.15 11.8 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Cadherin_C PF01049.12 EGO24855.1 - 0.074 13.0 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region bZIP_1 PF00170.16 EGO24857.1 - 0.0012 18.7 5.2 0.0017 18.2 1.5 2.1 2 0 0 2 2 2 1 bZIP transcription factor DUF972 PF06156.8 EGO24857.1 - 0.0027 18.0 3.1 0.0038 17.5 1.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF972) CCDC155 PF14662.1 EGO24857.1 - 0.0094 15.5 0.8 0.014 15.0 0.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Shugoshin_N PF07558.6 EGO24857.1 - 0.011 15.3 0.4 0.024 14.3 0.3 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CASP_C PF08172.7 EGO24857.1 - 0.038 12.9 1.0 0.059 12.3 0.7 1.3 1 0 0 1 1 1 0 CASP C terminal Striatin PF08232.7 EGO24857.1 - 0.053 13.8 2.5 0.073 13.3 1.7 1.4 1 1 0 1 1 1 0 Striatin family K-box PF01486.12 EGO24857.1 - 0.062 13.1 2.5 0.11 12.3 1.7 1.5 1 0 0 1 1 1 0 K-box region DivIC PF04977.10 EGO24857.1 - 0.24 10.8 6.3 0.18 11.3 2.8 1.9 1 1 0 1 1 1 0 Septum formation initiator Herpes_BLRF2 PF05812.7 EGO24857.1 - 0.3 10.8 3.8 1.1 9.1 2.6 2.2 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein HALZ PF02183.13 EGO24857.1 - 0.37 10.5 5.3 0.1 12.2 1.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 EGO24857.1 - 0.49 10.7 5.8 0.57 10.5 2.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 EGO24857.1 - 5.7 6.8 8.5 1 9.2 2.0 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4219 PF13961.1 EGO24858.1 - 0.18 11.2 0.5 0.38 10.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 EGO24859.1 - 0.024 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO24859.1 - 0.084 12.5 0.9 0.88 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO24859.1 - 1.6 8.6 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein Retrotrans_gag PF03732.12 EGO24860.1 - 2.5e-06 27.4 2.5 2.5e-06 27.4 1.7 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO24860.1 - 1.3e-05 24.8 1.5 2.9e-05 23.7 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO24860.1 - 0.00023 20.9 5.5 0.00038 20.2 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO24860.1 - 5.8 6.4 7.0 2.7 7.5 2.8 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-ribbon_3 PF13248.1 EGO24861.1 - 0.4 9.9 10.1 1.5 8.0 3.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain gag-asp_proteas PF13975.1 EGO24864.1 - 4.3e-07 29.6 0.0 6.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO24864.1 - 1.2e-06 28.8 0.0 1.5e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO24864.1 - 1.6e-06 28.1 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Transketolase_N PF00456.16 EGO24865.1 - 8e-19 67.6 1.7 1.1e-17 63.8 1.2 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EGO24865.1 - 7.1e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EGO24865.1 - 8.3e-06 25.4 0.1 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 EGO24865.1 - 0.0015 18.0 0.0 0.0061 16.1 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EGO24865.1 - 0.0036 16.0 0.0 0.0058 15.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF605 PF04652.11 EGO24867.1 - 0.012 15.0 16.1 0.015 14.7 11.2 1.0 1 0 0 1 1 1 0 Vta1 like BSP_II PF05432.6 EGO24867.1 - 0.052 12.8 6.0 0.071 12.3 4.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Orbi_VP6 PF01516.11 EGO24867.1 - 0.23 10.4 3.1 0.32 10.0 2.2 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF2457 PF10446.4 EGO24867.1 - 0.29 9.8 7.5 0.36 9.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 EGO24867.1 - 0.45 8.3 4.9 0.59 7.9 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGO24867.1 - 4.2 5.1 7.3 5 4.9 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family Hus1 PF04005.7 EGO24868.1 - 6.2e-78 261.6 0.3 7e-78 261.5 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad9 PF04139.8 EGO24868.1 - 0.026 13.6 1.3 0.049 12.7 0.9 1.4 1 0 0 1 1 1 0 Rad9 Ribosomal_S16 PF00886.14 EGO24869.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S16 Steroid_dh PF02544.11 EGO24870.1 - 1.3e-33 115.9 4.2 2e-33 115.2 2.9 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EGO24870.1 - 0.0005 20.1 1.4 0.0005 20.1 1.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase RabGAP-TBC PF00566.13 EGO24870.1 - 0.11 11.9 0.5 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 Rab-GTPase-TBC domain Abhydrolase_6 PF12697.2 EGO24871.1 - 2.5e-20 73.3 0.0 3.3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24871.1 - 4.3e-14 52.4 0.0 5.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO24871.1 - 6.6e-10 38.9 0.1 5.3e-09 35.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGO24871.1 - 1.3e-08 35.3 0.0 1.8e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGO24871.1 - 4e-08 33.1 0.0 6.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EGO24871.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGO24871.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 EGO24871.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 EGO24871.1 - 0.0044 16.9 0.2 0.0078 16.1 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_3 PF07859.8 EGO24871.1 - 0.006 16.1 0.0 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EGO24871.1 - 0.016 14.3 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EGO24871.1 - 0.027 13.3 0.1 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2048 PF09752.4 EGO24871.1 - 0.061 12.1 0.0 4.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Chlorophyllase PF07224.6 EGO24871.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.6 EGO24871.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_2 PF01674.13 EGO24871.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) MIP PF00230.15 EGO24872.1 - 9.6e-45 152.7 16.4 1.2e-44 152.4 11.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein RF-1 PF00472.15 EGO24873.1 - 4e-15 55.6 0.4 6e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain Herpes_IE2_3 PF03361.9 EGO24873.1 - 0.011 15.0 0.2 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 MRP-S28 PF10213.4 EGO24873.1 - 0.035 14.1 0.1 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein DUF4419 PF14388.1 EGO24874.1 - 2.9e-92 309.0 0.0 3.6e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF829 PF05705.9 EGO24875.1 - 4.6e-41 141.1 0.1 5.8e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EGO24875.1 - 0.0045 16.8 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4604 PF15377.1 EGO24876.1 - 6.3e-07 29.7 15.0 1.7e-06 28.3 10.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Complex1_LYR PF05347.10 EGO24877.1 - 2.9e-13 49.4 0.0 5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO24877.1 - 5.1e-11 42.6 0.0 9.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGO24877.1 - 2.9e-07 30.9 0.0 3.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Cyanate_lyase PF02560.9 EGO24878.1 - 6.9e-35 118.4 0.0 9.7e-35 117.9 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 EGO24878.1 - 0.00061 19.9 0.0 0.00096 19.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cyanate_lyase PF02560.9 EGO24880.1 - 6.8e-20 70.3 0.2 1.9e-19 68.9 0.2 1.7 1 1 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 EGO24880.1 - 0.00091 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1479 PF07350.7 EGO24881.1 - 2.2e-132 441.5 0.0 2.6e-132 441.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EGO24881.1 - 0.00023 21.2 0.6 0.18 11.8 0.1 3.0 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Tubulin PF00091.20 EGO24882.1 - 7.1e-66 222.1 0.0 1e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO24882.1 - 5.5e-39 133.0 0.1 8.9e-39 132.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGO24882.1 - 2.4e-08 34.0 0.2 6.7e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGO24882.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pho88 PF10032.4 EGO24883.1 - 4.2e-73 244.6 0.0 4.7e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CitMHS PF03600.11 EGO24883.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter PH PF00169.24 EGO24884.1 - 8.8e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Carbpep_Y_N PF05388.6 EGO24884.1 - 0.42 10.7 3.2 9.6 6.4 0.5 2.4 1 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide Nnf1 PF03980.9 EGO24884.1 - 1.9 8.5 5.3 0.29 11.1 0.3 2.1 3 0 0 3 3 3 0 Nnf1 Mito_carr PF00153.22 EGO24886.1 - 1.1e-65 217.3 7.3 2.1e-23 81.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Isochorismatase PF00857.15 EGO24887.1 - 3.1e-20 72.8 0.0 4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Glutaredoxin PF00462.19 EGO24890.1 - 1.2e-19 69.9 0.1 7.4e-19 67.5 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGO24890.1 - 3e-14 52.5 0.0 5.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGO24890.1 - 3.1e-05 23.9 0.0 0.007 16.4 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EGO24890.1 - 0.006 16.4 0.0 0.034 14.0 0.0 2.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EGO24890.1 - 0.0089 15.8 0.1 0.053 13.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EGO24890.1 - 0.02 15.1 0.0 0.56 10.4 0.0 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain ArsC PF03960.10 EGO24890.1 - 0.023 14.7 0.0 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 ArsC family DIM1 PF02966.11 EGO24890.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 2 0 0 2 2 2 0 Mitosis protein DIM1 Ku PF02735.11 EGO24891.1 - 3.7e-26 91.7 0.0 4.5e-25 88.2 0.0 2.3 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGO24891.1 - 4.4e-20 72.0 0.1 7.3e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 EGO24891.1 - 2e-10 39.8 0.1 4.9e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 EGO24891.1 - 5.7e-05 23.5 0.1 0.00017 22.0 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm PTPA PF03095.10 EGO24892.1 - 2.1e-93 312.7 0.0 2.6e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Orn_Arg_deC_N PF02784.11 EGO24894.1 - 8.2e-69 231.5 0.0 1.1e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGO24894.1 - 3e-31 107.5 0.0 5.1e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KilA-N PF04383.8 EGO24896.1 - 0.0027 17.2 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 KilA-N domain SPX PF03105.14 EGO24899.1 - 8.8e-40 137.2 2.4 1.3e-39 136.6 1.7 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EGO24899.1 - 2.5e-34 118.9 27.4 3.4e-34 118.5 19.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EGO24899.1 - 2.1e-16 59.4 26.4 3.3e-13 48.9 8.3 2.2 1 1 1 2 2 2 2 Citrate transporter PBP1_TM PF14812.1 EGO24899.1 - 0.01 16.1 8.3 0.033 14.4 5.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 EGO24899.1 - 0.22 9.3 0.5 0.36 8.6 0.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-Q PF13094.1 EGO24900.1 - 0.0044 17.0 0.8 0.028 14.4 0.8 1.9 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2730 PF10805.3 EGO24900.1 - 0.11 12.2 0.5 0.55 9.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CCDC-167 PF15188.1 EGO24900.1 - 0.42 10.5 2.2 0.73 9.8 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-C3HC4_3 PF13920.1 EGO24901.1 - 8.9e-09 34.8 7.4 1.5e-08 34.1 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO24901.1 - 3.7e-07 30.0 11.1 6.6e-07 29.2 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO24901.1 - 1.3e-06 27.9 9.5 2.4e-06 27.1 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO24901.1 - 9.9e-06 25.2 10.2 1.8e-05 24.4 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGO24901.1 - 1.2e-05 24.8 8.2 2.4e-05 23.9 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO24901.1 - 0.83 9.5 11.9 11 5.9 8.6 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING COPIIcoated_ERV PF07970.7 EGO24902.1 - 2e-37 128.9 1.3 3e-37 128.4 0.9 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGO24902.1 - 9.3e-19 67.2 0.2 2e-18 66.1 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SET PF00856.23 EGO24903.1 - 5.2e-17 62.6 0.7 5.2e-17 62.6 0.5 2.8 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.11 EGO24903.1 - 5.6e-13 49.0 5.2 5.6e-13 49.0 3.6 2.0 2 0 0 2 2 2 1 Pre-SET motif F-box-like PF12937.2 EGO24905.1 - 4.3e-13 48.7 2.5 2.1e-06 27.3 0.4 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EGO24905.1 - 0.032 13.8 3.9 0.33 10.6 0.1 2.8 2 1 0 2 2 2 0 F-box domain FPN1 PF06963.7 EGO24908.1 - 2.8e-130 434.6 18.1 3.2e-130 434.3 12.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) F-box-like PF12937.2 EGO24909.1 - 9e-07 28.5 0.2 3.5e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EGO24909.1 - 0.083 12.6 0.2 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 EGO24910.1 - 5.7e-08 32.3 0.5 1.9e-07 30.6 0.3 2.0 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.16 EGO24913.1 - 1.4e-90 303.9 0.0 1.6e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_assoc PF14363.1 EGO24914.1 - 0.032 14.2 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA HSF_DNA-bind PF00447.12 EGO24914.1 - 0.11 12.6 0.1 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Codanin-1_C PF15296.1 EGO24916.1 - 0.016 15.0 2.3 0.066 13.0 1.6 2.1 1 0 0 1 1 1 0 Codanin-1 C-terminus DivIC PF04977.10 EGO24916.1 - 0.45 10.0 16.1 0.29 10.6 1.0 3.0 2 0 0 2 2 2 0 Septum formation initiator APH PF01636.18 EGO24917.1 - 6.8e-07 29.2 0.0 1.3e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4436 PF14494.1 EGO24918.1 - 9.5e-11 41.4 1.3 1.7e-10 40.6 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4436 PF14494.1 EGO24919.1 - 5.8e-06 25.7 0.3 6.4e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) MFS_1 PF07690.11 EGO24920.1 - 1.8e-32 112.4 19.5 1.8e-32 112.4 13.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO24920.1 - 4.4e-07 28.4 1.1 8.6e-07 27.5 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO24920.1 - 0.016 13.6 0.6 0.016 13.6 0.4 2.8 2 2 0 2 2 2 0 MFS/sugar transport protein COesterase PF00135.23 EGO24921.1 - 7.4e-168 559.5 5.9 1.9e-88 297.4 0.8 2.6 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO24921.1 - 6.1e-12 45.5 7.9 3e-05 23.6 2.2 3.4 2 2 0 2 2 2 2 alpha/beta hydrolase fold PsbI PF02532.9 EGO24921.1 - 0.47 10.1 7.8 23 4.7 0.2 4.2 4 0 0 4 4 4 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) COesterase PF00135.23 EGO24922.1 - 1.2e-81 275.0 2.9 3.6e-81 273.4 2.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO24922.1 - 5.9e-06 26.0 1.5 2.7e-05 23.8 1.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO24922.1 - 0.02 14.1 0.3 0.034 13.3 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PsbI PF02532.9 EGO24922.1 - 0.075 12.6 1.1 8.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ribosomal_L30 PF00327.15 EGO24924.1 - 9e-10 37.9 0.5 1.6e-09 37.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Abhydrolase_6 PF12697.2 EGO24925.1 - 2.7e-21 76.5 0.5 3.7e-21 76.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24925.1 - 2.5e-06 27.3 0.0 4.1e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGO24925.1 - 0.00011 22.4 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EGO24925.1 - 0.011 15.3 0.0 0.3 10.6 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGO24925.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase AAA PF00004.24 EGO24926.1 - 4.8e-94 311.5 0.0 1.6e-47 160.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO24926.1 - 7e-16 57.9 0.0 1.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGO24926.1 - 8.5e-15 55.0 0.1 0.0023 18.0 0.0 5.4 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EGO24926.1 - 5.5e-13 49.3 1.8 9.3e-05 22.4 0.1 4.1 3 2 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EGO24926.1 - 2.1e-12 47.9 0.0 1e-06 29.5 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGO24926.1 - 1.6e-10 40.8 0.5 0.001 18.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGO24926.1 - 2.2e-10 40.5 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGO24926.1 - 5e-10 39.5 0.0 0.00067 19.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EGO24926.1 - 1.4e-09 37.8 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGO24926.1 - 5.1e-09 35.3 0.0 5.7e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EGO24926.1 - 2.3e-08 33.4 0.0 0.0048 16.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EGO24926.1 - 3.1e-08 33.7 0.0 0.011 15.8 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EGO24926.1 - 5.6e-08 32.3 0.0 0.0082 15.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGO24926.1 - 1.4e-07 31.1 4.3 0.0029 17.3 0.2 3.9 4 1 0 4 4 2 2 Part of AAA domain Mg_chelatase PF01078.16 EGO24926.1 - 4.8e-07 29.1 1.0 0.028 13.5 0.0 2.8 2 1 1 3 3 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGO24926.1 - 5.4e-07 29.4 0.8 0.085 12.5 0.0 4.0 3 1 1 4 4 4 2 NACHT domain AAA_28 PF13521.1 EGO24926.1 - 5.6e-07 29.6 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGO24926.1 - 1.6e-06 27.6 7.2 0.53 9.6 0.0 4.7 3 2 2 5 5 5 2 AAA domain AAA_18 PF13238.1 EGO24926.1 - 2.4e-06 27.8 0.0 0.037 14.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EGO24926.1 - 5.6e-06 26.6 0.0 0.096 12.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.6 EGO24926.1 - 1.6e-05 24.4 0.0 0.038 13.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGO24926.1 - 2.5e-05 23.8 0.0 0.39 10.1 0.0 3.6 3 1 0 3 3 3 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGO24926.1 - 4.5e-05 23.5 0.0 0.42 10.6 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EGO24926.1 - 5.2e-05 22.4 0.1 0.96 8.5 0.0 3.2 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 EGO24926.1 - 0.00016 20.6 0.0 0.0068 15.3 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 EGO24926.1 - 0.00017 20.5 0.0 0.36 9.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 EGO24926.1 - 0.00018 21.0 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 EGO24926.1 - 0.0002 21.3 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 EGO24926.1 - 0.0003 20.7 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase Arch_ATPase PF01637.13 EGO24926.1 - 0.00034 20.4 0.0 2 8.0 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase PhoH PF02562.11 EGO24926.1 - 0.00092 18.5 0.3 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 EGO24926.1 - 0.0012 17.8 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EGO24926.1 - 0.002 16.9 0.0 0.56 8.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 EGO24926.1 - 0.002 17.7 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EGO24926.1 - 0.0031 17.0 0.0 0.77 9.2 0.0 3.1 4 0 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EGO24926.1 - 0.0076 15.8 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGO24926.1 - 0.01 15.5 0.0 2.1 8.0 0.0 2.8 2 1 1 3 3 2 0 NTPase AAA_24 PF13479.1 EGO24926.1 - 0.015 14.9 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGO24926.1 - 0.017 14.0 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 EGO24926.1 - 0.025 14.2 0.0 3.6 7.1 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein T2SE PF00437.15 EGO24926.1 - 0.057 12.3 0.0 3.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.11 EGO24926.1 - 0.058 12.1 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.4 EGO24926.1 - 0.063 12.7 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGO24926.1 - 0.07 12.3 0.0 9.3 5.4 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ResIII PF04851.10 EGO24926.1 - 0.076 12.8 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EGO24926.1 - 0.12 11.8 0.3 25 4.1 0.0 3.0 3 1 0 4 4 3 0 AAA-like domain MMR_HSR1 PF01926.18 EGO24926.1 - 0.14 12.1 0.0 26 4.8 0.0 3.3 2 1 1 3 3 3 0 50S ribosome-binding GTPase CPT PF07931.7 EGO24926.1 - 0.14 11.7 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.11 EGO24926.1 - 0.15 11.1 0.1 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase FeoB_N PF02421.13 EGO24926.1 - 0.27 10.4 0.2 7.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PTCB-BRCT PF12738.2 EGO24927.1 - 2.4e-38 129.8 0.0 2.6e-14 52.7 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EGO24927.1 - 9.2e-25 86.6 0.0 3.7e-08 33.3 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain CK_II_beta PF01214.13 EGO24929.1 - 1e-71 240.2 0.0 1.2e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MBOAT PF03062.14 EGO24930.1 - 1.7e-43 148.9 26.3 1.7e-43 148.9 18.3 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family FAD_binding_3 PF01494.14 EGO24931.1 - 2e-14 53.4 0.2 2.6e-13 49.7 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO24931.1 - 1e-10 41.0 0.8 1.2e-06 27.7 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO24931.1 - 2.3e-08 33.9 0.8 2.3e-08 33.9 0.6 2.4 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO24931.1 - 6.5e-08 31.8 1.2 1.2e-07 31.0 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGO24931.1 - 1.8e-07 30.6 0.1 2.5e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO24931.1 - 1.2e-06 27.2 0.4 2.8e-06 26.0 0.3 1.6 1 1 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EGO24931.1 - 6.4e-05 22.0 0.9 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGO24931.1 - 0.00013 22.1 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO24931.1 - 0.00029 20.7 1.4 0.00077 19.3 1.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO24931.1 - 0.00088 18.4 0.3 0.0016 17.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGO24931.1 - 0.0044 17.4 2.0 0.018 15.4 0.8 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO24931.1 - 0.019 13.8 1.7 0.044 12.6 1.2 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 EGO24931.1 - 0.03 13.4 1.0 0.86 8.5 0.5 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EGO24931.1 - 0.049 12.2 0.5 0.62 8.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HSP20 PF00011.16 EGO24933.1 - 3.7e-21 74.9 0.1 4.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 EGO24933.1 - 0.00037 20.1 0.2 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 BON domain Imm45 PF15603.1 EGO24933.1 - 0.0089 16.1 0.1 0.033 14.3 0.0 1.8 2 0 0 2 2 2 1 Immunity protein 45 Rib PF08428.5 EGO24933.1 - 0.053 13.2 0.1 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Rib/alpha-like repeat HMA PF00403.21 EGO24933.1 - 0.087 12.9 0.0 0.83 9.8 0.0 2.0 2 0 0 2 2 2 0 Heavy-metal-associated domain CS PF04969.11 EGO24933.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.8 1 1 0 1 1 1 0 CS domain Retrotrans_gag PF03732.12 EGO24936.1 - 6.1e-06 26.2 5.5 4.5e-05 23.4 3.8 2.1 1 1 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 EGO24937.1 - 0.0088 15.9 0.1 0.012 15.5 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Y_phosphatase3 PF13350.1 EGO24938.1 - 1.2e-23 84.1 0.0 1.7e-15 57.6 0.0 2.1 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO24938.1 - 1.4e-06 28.3 0.0 7.1e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO24938.1 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO24938.1 - 3.3e-05 23.3 0.0 5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGO24938.1 - 0.00047 19.7 0.0 0.00089 18.8 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO24938.1 - 0.0094 16.0 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Rhodanese PF00581.15 EGO24938.1 - 0.043 14.1 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Myotub-related PF06602.9 EGO24938.1 - 0.066 11.9 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glypican PF01153.14 EGO24938.1 - 0.16 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Glypican Y_phosphatase3 PF13350.1 EGO24939.1 - 5e-27 95.1 0.0 8.4e-23 81.4 0.0 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO24939.1 - 2.3e-24 85.2 0.1 1.1e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGO24939.1 - 7.8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO24939.1 - 1.8e-05 24.2 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGO24939.1 - 0.0005 20.1 0.0 0.0021 18.1 0.0 2.0 2 1 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 EGO24939.1 - 0.003 17.1 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EGO24939.1 - 0.024 13.4 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain WD40 PF00400.27 EGO24941.1 - 7.6e-09 35.1 6.5 0.0025 17.6 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat DNA_pol_B PF00136.16 EGO24942.1 - 2.1e-93 313.6 0.0 3e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGO24942.1 - 9.7e-28 96.9 0.1 3.1e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGO24942.1 - 8.7e-14 51.2 3.1 1.7e-13 50.3 2.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Sema PF01403.14 EGO24942.1 - 0.054 12.0 0.1 0.085 11.3 0.1 1.2 1 0 0 1 1 1 0 Sema domain DNA_pol_B_2 PF03175.8 EGO24942.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral SET PF00856.23 EGO24943.1 - 2.2e-06 28.0 0.0 0.00014 22.2 0.0 2.3 1 1 0 1 1 1 1 SET domain CBM_X PF06204.6 EGO24943.1 - 0.046 13.2 0.2 0.093 12.2 0.2 1.5 1 0 0 1 1 1 0 Putative carbohydrate binding domain APG12 PF04110.8 EGO24946.1 - 0.011 15.9 0.2 2.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 UBN2_3 PF14244.1 EGO24946.1 - 0.021 14.3 0.9 0.11 12.0 0.6 2.1 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EGO24946.1 - 0.022 14.7 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Mito_fiss_reg PF05308.6 EGO24946.1 - 0.48 9.7 5.4 1.1 8.6 3.8 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator PepSY_TM_1 PF13172.1 EGO24947.1 - 4.7 7.0 7.3 0.85 9.4 1.8 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO24948.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO24948.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO24948.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.2 EGO24950.1 - 0.00013 21.6 1.9 0.37 10.5 0.3 2.6 2 0 0 2 2 2 2 F-box-like p450 PF00067.17 EGO24952.1 - 3.9e-57 193.8 0.0 1.2e-55 188.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF4470 PF14737.1 EGO24953.1 - 1.4e-18 66.4 0.0 5.2e-18 64.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_12 PF13424.1 EGO24953.1 - 3.7e-14 52.3 11.6 0.00035 20.4 0.0 4.5 4 1 1 5 5 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 EGO24953.1 - 3.6e-10 39.1 0.0 6.8e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EGO24953.1 - 3.3e-08 32.8 11.7 0.13 12.2 0.9 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGO24953.1 - 4.7e-06 26.3 7.6 0.23 11.4 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.1 EGO24953.1 - 5.9e-06 25.6 5.2 0.0065 15.6 0.0 4.0 2 1 2 4 4 4 1 Soluble NSF attachment protein, SNAP NACHT PF05729.7 EGO24953.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 EGO24953.1 - 3.5e-05 23.2 1.5 0.092 12.5 0.6 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGO24953.1 - 0.00061 19.9 0.4 0.038 14.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain TPR_1 PF00515.23 EGO24953.1 - 0.00066 19.1 10.0 0.22 11.2 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO24953.1 - 0.0008 19.0 2.9 0.015 15.0 0.4 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO24953.1 - 0.0015 18.1 10.2 0.51 10.0 0.3 4.5 4 1 0 4 4 4 2 TPR repeat AAA_16 PF13191.1 EGO24953.1 - 0.0016 18.4 1.8 0.14 12.0 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain Prominin PF05478.6 EGO24953.1 - 0.0032 15.1 0.3 0.0052 14.3 0.2 1.2 1 0 0 1 1 1 1 Prominin AAA PF00004.24 EGO24953.1 - 0.0082 16.3 0.0 0.029 14.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.4 EGO24953.1 - 0.02 14.2 0.3 0.036 13.4 0.2 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 Apc3 PF12895.2 EGO24953.1 - 0.026 14.6 8.8 1.5 9.0 0.0 4.5 2 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGO24953.1 - 0.035 14.7 8.4 4 8.2 0.6 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGO24953.1 - 0.068 12.4 1.5 0.11 11.7 0.1 2.1 2 0 0 2 2 2 0 SHNi-TPR DUF4381 PF14316.1 EGO24956.1 - 0.026 14.6 0.3 0.028 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RNase_P_Rpp14 PF01900.14 EGO24957.1 - 2.1e-29 101.5 0.1 2.6e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Raffinose_syn PF05691.7 EGO24957.1 - 0.012 13.2 0.0 0.015 12.8 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DUF1186 PF06685.6 EGO24960.1 - 0.0089 15.2 4.9 0.0089 15.2 3.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1186) DUF2317 PF10079.4 EGO24960.1 - 0.34 9.4 13.9 0.46 9.0 9.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PIN_4 PF13638.1 EGO24960.1 - 3.8 7.6 12.0 31 4.6 5.5 2.9 1 1 1 2 2 2 0 PIN domain Mto2_bdg PF12808.2 EGO24960.1 - 9.2 6.4 12.6 12 6.0 0.1 4.1 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4139 PF13598.1 EGO24962.1 - 1.1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) SSF PF00474.12 EGO24963.1 - 1.8e-19 69.6 28.3 3.3e-19 68.8 19.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2663 PF10864.3 EGO24963.1 - 0.31 11.2 3.9 0.54 10.4 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) NPCC PF08058.6 EGO24963.1 - 3.6 7.4 5.1 25 4.7 0.2 3.2 3 0 0 3 3 3 0 Nuclear pore complex component FmdA_AmdA PF03069.10 EGO24964.1 - 2.2e-121 405.0 0.0 2.7e-121 404.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Sdh_cyt PF01127.17 EGO24965.1 - 5.1e-24 84.4 0.9 6.4e-24 84.1 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PXA PF02194.10 EGO24968.1 - 5.7e-39 133.5 0.1 5.7e-39 133.5 0.1 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EGO24968.1 - 2.5e-28 98.4 0.0 1.3e-27 96.0 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EGO24968.1 - 7e-18 64.4 0.0 2.9e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EGO24968.1 - 4.4e-09 36.4 0.1 1e-08 35.3 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Hce2 PF14856.1 EGO24970.1 - 8e-06 25.6 0.3 1.2e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor TF_Otx PF03529.8 EGO24970.1 - 0.088 13.0 2.5 0.13 12.5 1.7 1.4 1 1 0 1 1 1 0 Otx1 transcription factor DHFR_2 PF06442.6 EGO24970.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 R67 dihydrofolate reductase Amidase PF01425.16 EGO24971.1 - 1.4e-100 337.2 0.0 1.6e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 Amidase LRR_4 PF12799.2 EGO24972.1 - 0.023 14.3 7.7 0.031 13.8 0.8 3.4 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGO24972.1 - 0.047 13.7 8.7 17 5.8 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich repeat RabGAP-TBC PF00566.13 EGO24973.1 - 6.2e-48 163.1 0.0 1.2e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COX6B PF02297.12 EGO24974.1 - 9.4e-22 76.8 3.3 1.2e-21 76.4 2.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EGO24974.1 - 0.0023 17.9 1.2 0.0032 17.4 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 EGO24974.1 - 0.045 13.7 2.3 0.18 11.7 1.5 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein TPR_11 PF13414.1 EGO24976.1 - 5.6e-16 57.9 4.0 8.1e-11 41.4 1.4 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGO24976.1 - 5.1e-12 44.8 4.3 0.0024 17.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO24976.1 - 2e-10 39.7 6.1 0.0003 20.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO24976.1 - 7.4e-08 32.6 0.3 8.2e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO24976.1 - 1.2e-05 25.8 4.5 0.00036 21.1 0.2 2.7 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO24976.1 - 0.00012 21.6 1.1 0.073 12.9 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO24976.1 - 0.00025 20.6 0.3 0.061 13.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO24976.1 - 0.0003 21.1 7.5 0.14 12.8 0.0 3.8 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO24976.1 - 0.00036 20.4 5.3 0.0071 16.2 0.6 3.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO24976.1 - 0.00073 19.8 6.7 0.095 13.2 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO24976.1 - 0.0046 17.0 0.3 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGO24976.1 - 0.017 14.2 0.6 0.1 11.6 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGO24976.1 - 0.021 14.6 0.6 8.5 6.3 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO24976.1 - 0.046 13.6 0.7 0.3 11.0 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO24976.1 - 0.056 13.3 0.6 18 5.2 0.0 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Phage_P2_GpE PF06528.7 EGO24976.1 - 0.14 11.6 2.3 0.16 11.4 0.2 2.2 2 0 0 2 2 2 0 Phage P2 GpE Abhydrolase_6 PF12697.2 EGO24977.1 - 5.9e-12 45.9 0.0 8e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO24977.1 - 2.8e-10 40.1 0.0 3.6e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO24977.1 - 1.5e-06 27.9 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EGO24977.1 - 3.2e-06 26.7 0.0 4.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EGO24977.1 - 0.00069 19.1 0.0 0.002 17.5 0.0 1.8 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 EGO24977.1 - 0.0077 14.7 0.0 0.012 14.1 0.0 1.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 EGO24977.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1749 PF08538.5 EGO24977.1 - 0.13 11.0 0.0 2.5 6.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) MFS_1 PF07690.11 EGO24979.1 - 2.2e-26 92.4 29.5 3.3e-19 68.8 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO24979.1 - 3e-20 72.2 16.5 6.1e-20 71.2 11.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.1 EGO24979.1 - 0.11 11.9 0.0 0.11 11.9 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Arrestin_N PF00339.24 EGO24980.1 - 1.7e-06 27.9 1.1 1.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGO24980.1 - 8.1e-05 22.7 0.0 0.007 16.4 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Glyco_transf_8 PF01501.15 EGO24981.1 - 1.1e-27 96.9 0.0 1.8e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 EGO24981.1 - 3.7e-17 63.0 0.0 2.6e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGO24981.1 - 0.0016 17.5 0.0 0.004 16.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Glyco_trans_4_4 PF13579.1 EGO24981.1 - 0.016 15.3 0.3 0.035 14.2 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Methyltransf_18 PF12847.2 EGO24981.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_2 PF00535.21 EGO24982.1 - 2.7e-15 56.4 0.1 6.7e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Epimerase PF01370.16 EGO24982.1 - 1.9e-13 50.4 0.0 3.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tranf_2_3 PF13641.1 EGO24982.1 - 2.7e-09 37.1 0.2 8e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGO24982.1 - 8e-06 25.1 0.0 1.9e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.1 EGO24982.1 - 0.031 13.5 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 3Beta_HSD PF01073.14 EGO24982.1 - 0.087 11.5 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DBR1 PF05011.8 EGO24983.1 - 1.4e-30 106.0 0.0 2.6e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGO24983.1 - 3.9e-09 36.1 2.5 6.2e-09 35.5 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO24983.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SSF PF00474.12 EGO24984.1 - 6.3e-21 74.4 32.9 6.3e-21 74.4 22.8 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.4 EGO24984.1 - 0.12 10.8 0.0 0.12 10.8 0.0 3.8 3 1 0 4 4 4 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.1 EGO24984.1 - 7.3 6.3 13.3 4.9 6.9 3.1 3.0 2 0 0 2 2 2 0 CoA-binding domain P5-ATPase PF12409.3 EGO24985.1 - 0.0014 18.4 1.3 0.002 17.9 0.9 1.2 1 0 0 1 1 1 1 P5-type ATPase cation transporter Tmemb_185A PF10269.4 EGO24985.1 - 0.0084 15.7 0.5 0.011 15.3 0.4 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF544 PF04424.8 EGO24986.1 - 8.7e-17 61.0 0.1 2.1e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF544) eIF-3_zeta PF05091.7 EGO24986.1 - 0.36 9.3 5.2 0.5 8.9 3.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Uricase PF01014.13 EGO24990.1 - 6e-66 220.7 0.0 9.1e-39 132.7 0.1 2.3 2 1 0 2 2 2 2 Uricase Lyase_1 PF00206.15 EGO24991.1 - 9.7e-120 399.4 0.0 1.3e-119 399.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGO24991.1 - 3.8e-20 71.6 0.0 8.3e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EGO24991.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-CCHC PF00098.18 EGO24992.1 - 1e-13 50.4 13.3 5.8e-08 32.3 3.3 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.12 EGO24992.1 - 6.2e-09 35.8 1.3 6.2e-09 35.8 0.9 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EGO24992.1 - 0.00079 19.0 7.6 0.012 15.2 0.4 2.8 2 0 0 2 2 2 2 Zinc knuckle Herpes_UL55 PF04537.7 EGO24992.1 - 0.0069 15.7 0.3 0.12 11.7 0.0 2.4 2 1 0 2 2 2 1 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO24992.1 - 0.0079 15.9 9.5 0.077 12.7 1.5 2.5 2 0 0 2 2 2 2 Zinc knuckle Musclin PF11037.3 EGO24992.1 - 0.057 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle zf-CCHC_6 PF15288.1 EGO24992.1 - 4.6 6.9 9.0 16 5.2 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle MULE PF10551.4 EGO24993.1 - 2.6e-06 27.4 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.12 EGO24993.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase gag-asp_proteas PF13975.1 EGO24994.1 - 1.5e-09 37.5 0.0 2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO24994.1 - 1.3e-06 28.3 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO24994.1 - 2.8e-05 24.5 0.1 5.4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO24994.1 - 0.086 12.4 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.20 EGO24997.1 - 3.3e-06 26.4 0.0 5.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGO24997.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO24997.1 - 0.002 17.9 0.1 0.0044 16.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGO24997.1 - 0.0028 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO24997.1 - 0.025 13.9 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 EGO24997.1 - 0.083 12.0 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase ubiquitin PF00240.18 EGO24998.1 - 0.057 12.8 0.1 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family RGP PF03214.8 EGO25000.1 - 0.025 13.3 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Retrotrans_gag PF03732.12 EGO25004.1 - 4e-08 33.2 0.2 4e-08 33.2 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein MULE PF10551.4 EGO25005.1 - 3.5e-06 27.0 0.0 7.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.12 EGO25005.1 - 0.019 14.5 0.2 0.051 13.1 0.1 1.6 1 1 0 1 1 1 0 Transposase ubiquitin PF00240.18 EGO25006.1 - 0.049 13.0 0.1 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF1462 PF07315.6 EGO25006.1 - 0.067 13.1 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Pkinase PF00069.20 EGO25007.1 - 3.3e-06 26.4 0.0 5.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGO25007.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO25007.1 - 0.002 17.9 0.1 0.0044 16.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGO25007.1 - 0.0028 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO25007.1 - 0.025 13.9 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 EGO25007.1 - 0.083 12.0 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Sec63 PF02889.11 EGO25011.1 - 4.6e-14 52.3 0.0 7.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain ubiquitin PF00240.18 EGO25017.1 - 0.0029 16.9 0.7 2.1 7.7 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin family T4-Gluco-transf PF09198.5 EGO25017.1 - 0.53 9.6 2.6 22 4.4 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase zf-CCHC PF00098.18 EGO25021.1 - 0.00093 19.0 2.3 0.0016 18.2 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle ZZ PF00569.12 EGO25021.1 - 0.5 9.9 4.3 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type CHAT PF12770.2 EGO25026.1 - 1.5e-16 60.3 0.7 3.9e-15 55.7 0.5 2.4 1 1 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EGO25026.1 - 1e-08 35.0 23.6 0.0021 17.9 0.0 9.2 5 4 4 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO25026.1 - 3.1e-08 33.1 11.7 0.0013 18.3 0.0 7.5 7 2 2 9 9 9 2 TPR repeat TPR_7 PF13176.1 EGO25026.1 - 5e-06 25.9 3.2 3.3 7.7 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25026.1 - 0.00074 19.0 11.1 7.2 6.4 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat MIT PF04212.13 EGO25026.1 - 0.044 13.6 1.9 8.7 6.3 0.0 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain MFS_1 PF07690.11 EGO25027.1 - 8.6e-40 136.5 76.1 2e-35 122.1 36.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1391 PF07151.7 EGO25027.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Cpn10 PF00166.16 EGO25028.1 - 3.8e-26 90.8 0.0 4.3e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-MYND PF01753.13 EGO25029.1 - 6.3e-08 32.3 13.4 1.2e-07 31.4 9.3 1.5 1 0 0 1 1 1 1 MYND finger Sugar_tr PF00083.19 EGO25030.1 - 0.11 10.9 4.8 0.14 10.7 3.3 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.11 EGO25031.1 - 7.2e-13 47.9 25.9 3.8e-08 32.4 8.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_22 PF13401.1 EGO25032.1 - 0.034 14.2 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_S16 PF00886.14 EGO25032.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S16 Sugar_tr PF00083.19 EGO25033.1 - 9.3e-102 340.9 22.0 1.1e-101 340.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO25033.1 - 4.3e-24 84.8 44.7 4e-16 58.6 8.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily PNPase_C PF12111.3 EGO25034.1 - 0.068 12.3 0.5 0.2 10.9 0.1 1.9 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Thg1C PF14413.1 EGO25035.1 - 7.9e-46 154.6 0.1 1.1e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EGO25035.1 - 8.6e-44 148.4 0.0 1.3e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase UCH PF00443.24 EGO25037.1 - 2.7e-56 190.6 0.1 3.6e-56 190.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO25037.1 - 3.8e-25 88.9 0.1 6.1e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2701 PF10857.3 EGO25040.1 - 1.5 8.6 4.3 2 8.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) RVP_2 PF08284.6 EGO25041.1 - 3.2e-09 36.8 0.0 3.5e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO25041.1 - 7.6e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO25041.1 - 6.4e-05 23.3 0.0 7.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.3 EGO25041.1 - 0.00073 19.3 0.0 0.0008 19.2 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon peptidase APH PF01636.18 EGO25042.1 - 4.6e-07 29.8 0.1 4e-06 26.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3897 PF13036.1 EGO25045.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3897) CHAT PF12770.2 EGO25046.1 - 2.7e-31 108.7 0.0 4.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EGO25046.1 - 3.9e-15 55.5 17.3 0.79 9.6 0.0 12.9 7 2 7 14 14 14 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGO25046.1 - 1.6e-14 53.2 21.0 0.037 13.6 0.2 10.6 5 2 5 11 11 11 8 TPR repeat TPR_14 PF13428.1 EGO25046.1 - 4e-07 30.0 4.4 20 6.1 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25046.1 - 0.0078 16.3 13.9 1.1 9.6 0.1 8.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25046.1 - 1 9.4 11.7 55 4.0 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Sel1 PF08238.7 EGO25046.1 - 1.9 9.2 8.9 1.1e+02 3.5 0.0 6.7 9 0 0 9 9 9 0 Sel1 repeat NUDIX PF00293.23 EGO25048.1 - 2.5e-26 91.8 0.0 3.4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Mito_carr PF00153.22 EGO25049.1 - 5.8e-35 118.8 1.0 1.4e-16 59.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein RAI1 PF08652.6 EGO25052.1 - 8.2e-21 73.5 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease SUR7 PF06687.7 EGO25053.1 - 4.2e-16 59.1 20.8 5.5e-11 42.4 1.2 2.1 1 1 1 2 2 2 2 SUR7/PalI family Amastin PF07344.6 EGO25053.1 - 1.1 8.9 7.2 2.5 7.6 3.7 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein TGF_beta_GS PF08515.7 EGO25057.1 - 0.47 9.8 2.2 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif UXS1_N PF11803.3 EGO25058.1 - 0.14 11.9 0.1 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal GATA PF00320.22 EGO25060.1 - 2e-15 55.8 3.1 4.4e-15 54.7 2.1 1.6 1 0 0 1 1 1 1 GATA zinc finger Zip PF02535.17 EGO25060.1 - 0.0077 15.2 1.0 0.0094 14.9 0.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Dicty_REP PF05086.7 EGO25060.1 - 1.6 6.3 3.3 1.9 6.1 2.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 EGO25060.1 - 3.1 7.5 12.2 4.3 7.1 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Innate_immun PF12782.2 EGO25060.1 - 9 5.4 17.4 6 6.0 10.9 1.5 1 1 0 1 1 1 0 Invertebrate innate immunity transcript family TauD PF02668.11 EGO25063.1 - 1.4e-52 178.9 0.2 1.7e-52 178.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyt-b5 PF00173.23 EGO25064.1 - 1.5e-20 72.7 0.0 2.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cupin_1 PF00190.17 EGO25065.1 - 5.7e-28 97.1 0.0 2e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGO25065.1 - 1.8e-27 94.6 0.3 1.1e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGO25065.1 - 7.9e-11 41.1 0.0 0.00013 21.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EGO25065.1 - 4.8e-09 36.0 0.2 4.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EGO25065.1 - 2.9e-05 23.7 0.0 0.00045 19.8 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EGO25065.1 - 0.00038 19.9 0.0 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase CENP-C_C PF11699.3 EGO25065.1 - 0.00046 20.1 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_4 PF08007.7 EGO25065.1 - 0.0085 15.3 0.0 0.087 12.0 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein ARD PF03079.9 EGO25065.1 - 0.068 13.1 0.1 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family GMC_oxred_N PF00732.14 EGO25066.1 - 8.6e-65 218.8 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO25066.1 - 6.5e-35 120.5 0.0 1.2e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGO25066.1 - 0.00012 21.1 0.4 0.33 9.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO25066.1 - 0.00018 20.5 0.3 0.00047 19.1 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGO25066.1 - 0.0039 16.0 0.4 1.3 7.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGO25066.1 - 0.033 14.2 0.1 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Cu-oxidase PF00394.17 EGO25067.1 - 1.7e-45 154.7 0.0 3.4e-43 147.2 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO25067.1 - 1.2e-38 131.7 3.9 1.6e-36 124.8 0.0 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO25067.1 - 8.1e-38 128.7 3.1 7.8e-35 119.1 0.7 3.4 3 1 0 3 3 3 2 Multicopper oxidase Pheromone PF08015.6 EGO25068.1 - 0.056 14.2 3.0 0.41 11.5 2.1 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone Pheromone PF08015.6 EGO25069.1 - 0.023 15.5 5.1 0.39 11.5 3.6 2.1 1 1 0 1 1 1 0 Fungal mating-type pheromone RasGAP PF00616.14 EGO25070.1 - 2.9e-54 183.7 0.4 1.3e-53 181.6 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGO25070.1 - 6.1e-36 123.2 0.8 2e-35 121.5 0.6 2.0 1 0 0 1 1 1 1 RasGAP C-terminus KxDL PF10241.4 EGO25070.1 - 0.012 15.4 0.3 0.42 10.5 0.2 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF972 PF06156.8 EGO25070.1 - 0.03 14.6 2.0 7.9 6.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Glyco_trans_1_3 PF13528.1 EGO25071.1 - 5.8e-06 25.7 0.0 4.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 1 Aa_trans PF01490.13 EGO25072.1 - 3.2e-87 292.6 28.8 3.8e-87 292.4 20.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4499 PF14934.1 EGO25072.1 - 0.015 15.2 0.5 0.038 13.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Fungal_lectin PF07938.7 EGO25074.1 - 2.3e-09 36.9 0.2 2.3e-09 36.9 0.1 1.7 2 0 0 2 2 2 1 Fungal fucose-specific lectin CBM_1 PF00734.13 EGO25074.1 - 1.1e-07 31.3 8.1 2.8e-07 30.0 5.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain eIF3_subunit PF08597.5 EGO25076.1 - 3.5e-46 157.7 19.3 3.9e-46 157.6 13.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit WD40 PF00400.27 EGO25077.1 - 1.1e-22 78.9 14.0 5e-08 32.5 0.4 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat VSP PF03302.8 EGO25078.1 - 0.0025 16.5 7.0 0.0034 16.0 4.9 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein IER PF05760.7 EGO25078.1 - 3.9 7.3 8.3 6.9 6.5 5.7 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF202 PF02656.10 EGO25079.1 - 1.1e-09 38.3 5.2 1.8e-09 37.6 2.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4383 PF14325.1 EGO25079.1 - 0.0048 16.9 0.6 0.009 16.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF4131 PF13567.1 EGO25079.1 - 0.038 13.3 0.7 0.062 12.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NfeD PF01957.13 EGO25079.1 - 0.27 11.3 2.4 0.69 10.0 0.2 2.4 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding Pro_isomerase PF00160.16 EGO25081.1 - 9.3e-46 155.8 0.0 1.1e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F_actin_cap_B PF01115.12 EGO25082.1 - 5.2e-103 343.4 0.0 6e-103 343.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.20 EGO25084.1 - 3.7e-43 147.5 0.0 1.3e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25084.1 - 4.7e-20 71.7 0.0 4.7e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO25084.1 - 3e-05 23.1 0.0 0.0058 15.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGO25084.1 - 0.0043 16.8 0.2 0.026 14.2 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNB PF00773.14 EGO25085.1 - 8.8e-51 173.1 0.0 1.5e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 RNB domain RNase_PH PF01138.16 EGO25086.1 - 8.3e-34 116.7 0.1 2.2e-33 115.3 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGO25086.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.12 EGO25087.1 - 1.1e-55 187.7 0.0 1.5e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO25087.1 - 5.3e-07 30.2 0.0 8.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO25087.1 - 2.2e-05 24.4 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO25087.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO25087.1 - 0.017 14.5 0.0 0.07 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO25087.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EGO25087.1 - 0.085 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 EGO25087.1 - 0.11 13.0 0.0 0.43 11.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.17 EGO25088.1 - 1.2e-17 63.3 0.0 1.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EGO25088.1 - 2.2e-15 56.7 0.1 3.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 EGO25088.1 - 1.9e-14 53.3 0.0 2.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO25088.1 - 2e-10 40.3 0.0 3.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DASH_Dad2 PF08654.5 EGO25089.1 - 1.8e-10 40.7 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 PTSIIB_sorb PF03830.10 EGO25089.1 - 0.002 18.0 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 PTS system sorbose subfamily IIB component Med12 PF09497.5 EGO25090.1 - 1.8e-25 88.6 0.0 5.6e-25 87.1 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EGO25090.1 - 0.019 13.4 0.0 0.095 11.1 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain zf-C3HC4_2 PF13923.1 EGO25091.1 - 1.3e-06 28.2 7.8 1.8e-06 27.8 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25091.1 - 2.2e-05 24.0 8.6 5.7e-05 22.7 2.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO25091.1 - 3.3e-05 23.4 4.3 3.3e-05 23.4 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGO25091.1 - 6.1e-05 22.7 0.2 0.00015 21.4 0.1 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGO25091.1 - 0.00016 21.3 2.2 0.00016 21.3 1.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EGO25091.1 - 0.00065 19.4 13.3 0.0039 16.9 9.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGO25091.1 - 0.0014 18.4 3.0 0.0014 18.4 2.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EGO25091.1 - 0.0015 18.1 6.2 0.012 15.2 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO25091.1 - 0.0089 16.1 1.8 0.0089 16.1 1.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger DivIC PF04977.10 EGO25091.1 - 0.016 14.6 2.2 0.016 14.6 1.5 1.6 2 0 0 2 2 2 0 Septum formation initiator UPF0547 PF10571.4 EGO25091.1 - 0.065 12.9 1.7 4.6 7.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 V_ATPase_I PF01496.14 EGO25091.1 - 0.073 10.9 0.1 0.089 10.6 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATXN-1_C PF12547.3 EGO25091.1 - 0.096 12.6 0.3 8.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator zf-MIZ PF02891.15 EGO25091.1 - 0.67 9.5 5.1 0.78 9.3 1.0 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF904 PF06005.7 EGO25091.1 - 1.3 9.3 4.0 0.69 10.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) IBR PF01485.16 EGO25091.1 - 2.6 7.9 11.7 30 4.5 6.0 3.2 2 1 0 2 2 2 0 IBR domain BTB PF00651.26 EGO25092.1 - 1.3e-06 28.3 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF617 PF04759.8 EGO25094.1 - 0.043 13.4 0.1 0.057 13.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF617 NAD_kinase PF01513.16 EGO25095.1 - 1e-66 224.6 0.0 2.8e-66 223.2 0.0 1.7 1 0 0 1 1 1 1 ATP-NAD kinase DUF2419 PF10343.4 EGO25096.1 - 4.5e-08 32.6 0.0 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) YqeY PF09424.5 EGO25097.1 - 2.6e-19 69.4 0.1 3.6e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Yqey-like protein Amidohydro_3 PF07969.6 EGO25098.1 - 4.2e-67 227.1 0.0 4.8e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGO25098.1 - 9.1e-07 29.1 0.1 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO25098.1 - 6.3e-05 22.7 0.0 0.0068 16.1 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO25098.1 - 0.0037 17.0 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.18 EGO25099.1 - 2.9e-54 183.9 0.0 5.6e-54 182.9 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO25099.1 - 2.8e-10 39.8 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO25099.1 - 7.4e-06 24.9 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EGO25099.1 - 2.2e-05 24.0 0.0 0.00017 21.0 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO25099.1 - 0.008 16.0 0.0 0.099 12.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EGO25101.1 - 6.9e-34 114.5 16.8 1.1e-07 31.4 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EGO25101.1 - 0.0021 17.5 0.4 0.05 13.0 0.3 2.7 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EGO25101.1 - 0.0027 17.9 0.2 11 6.4 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain PQQ PF01011.16 EGO25101.1 - 0.0056 16.1 0.2 16 5.2 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat DUF3312 PF11768.3 EGO25101.1 - 0.12 10.5 0.0 7.4 4.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) F-box-like PF12937.2 EGO25102.1 - 1e-08 34.7 0.3 2.4e-08 33.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO25102.1 - 0.0034 16.9 0.0 0.0078 15.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Rep_fac_C PF08542.6 EGO25103.1 - 1.5e-20 72.9 0.1 1.4e-19 69.8 0.0 2.4 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGO25103.1 - 1.4e-12 47.5 0.1 3.2e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EGO25103.1 - 8e-06 26.0 0.2 2e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EGO25103.1 - 0.00011 21.8 0.3 0.00017 21.1 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EGO25103.1 - 0.00053 19.1 0.0 0.62 9.0 0.0 2.7 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EGO25103.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EGO25103.1 - 0.0016 18.4 1.6 0.028 14.4 0.5 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO25103.1 - 0.0021 18.1 1.2 0.031 14.4 0.6 2.8 1 1 1 2 2 2 1 AAA domain Lipoprotein_18 PF06804.6 EGO25103.1 - 0.021 13.5 0.5 0.043 12.5 0.3 1.4 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Sigma54_activ_2 PF14532.1 EGO25103.1 - 0.022 14.7 0.4 0.097 12.7 0.3 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 EGO25103.1 - 0.024 13.3 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SNF2_N PF00176.18 EGO25103.1 - 0.038 12.7 0.1 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain TSC21 PF15217.1 EGO25103.1 - 0.046 13.3 0.1 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 TSC21 family AAA_33 PF13671.1 EGO25103.1 - 0.049 13.5 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Prenyltransf PF01255.14 EGO25103.1 - 0.055 12.5 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase DUF968 PF06147.6 EGO25103.1 - 0.1 12.4 1.4 0.45 10.3 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF968) Thiolase_N PF00108.18 EGO25104.1 - 2.8e-68 229.7 0.1 5.7e-68 228.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO25104.1 - 8.2e-41 138.2 0.9 6.7e-40 135.3 0.2 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGO25104.1 - 0.0063 16.1 2.4 0.49 10.0 0.0 2.9 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGO25104.1 - 0.0065 15.9 1.9 0.014 14.9 0.3 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.7 EGO25104.1 - 0.014 14.5 0.0 0.079 12.0 0.0 2.1 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein An_peroxidase PF03098.10 EGO25105.1 - 5.7e-78 262.6 0.0 6.9e-76 255.7 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGO25105.1 - 0.00014 20.4 0.0 0.00092 17.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 GMC_oxred_N PF00732.14 EGO25108.1 - 7.5e-05 22.0 0.0 0.00034 19.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DASH_Spc34 PF08657.5 EGO25110.1 - 1.4e-05 24.8 8.1 5.1e-05 23.0 0.1 3.4 2 1 0 2 2 2 1 DASH complex subunit Spc34 MAP65_ASE1 PF03999.7 EGO25110.1 - 0.0073 14.9 0.5 0.0073 14.9 0.4 1.8 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Fic_N PF13784.1 EGO25110.1 - 0.21 11.4 2.0 0.62 9.9 0.2 2.5 2 0 0 2 2 2 0 Fic/DOC family N-terminal OmpH PF03938.9 EGO25110.1 - 1.1 9.2 7.5 0.071 13.0 1.3 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DOCK-C2 PF14429.1 EGO25112.1 - 1e-43 149.1 0.0 2.3e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EGO25112.1 - 1.3e-36 125.5 0.0 2.7e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis DUF4370 PF14290.1 EGO25113.1 - 0.089 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) RNase_Zc3h12a_2 PF14626.1 EGO25113.1 - 0.099 12.5 0.2 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Med27 PF11571.3 EGO25115.1 - 3.1e-07 30.4 0.0 8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 Hydrophobin PF01185.13 EGO25118.1 - 5.2e-25 87.6 11.8 6.5e-25 87.3 8.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin LETM1 PF07766.8 EGO25119.1 - 2e-21 76.2 1.3 2e-10 40.1 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF3640 PF12342.3 EGO25119.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) TPR_11 PF13414.1 EGO25120.1 - 1.2e-38 130.5 36.5 8.3e-08 31.7 0.7 12.9 9 5 6 15 15 15 11 TPR repeat TPR_16 PF13432.1 EGO25120.1 - 4.4e-32 110.0 52.7 1.4e-08 35.2 1.8 11.9 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25120.1 - 1.4e-24 84.6 21.3 7.1e-05 22.2 0.2 12.1 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25120.1 - 3.1e-22 76.6 42.0 0.00071 19.2 0.2 15.0 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25120.1 - 1.9e-20 71.2 19.6 0.0063 16.6 0.1 12.2 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGO25120.1 - 5.6e-20 71.4 41.6 0.0029 17.9 0.8 11.1 10 2 2 12 12 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25120.1 - 4.7e-19 67.1 61.0 0.012 16.1 0.4 17.4 12 6 6 18 18 17 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25120.1 - 4.9e-17 60.3 12.9 0.0011 18.5 0.2 12.4 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25120.1 - 2.2e-15 56.3 43.7 0.00061 19.6 0.2 11.4 10 3 3 14 14 14 7 Tetratricopeptide repeat Apc3 PF12895.2 EGO25120.1 - 1.4e-09 37.9 9.7 0.016 15.3 0.1 8.0 7 2 2 9 9 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGO25120.1 - 6.1e-05 22.7 46.3 0.069 13.0 0.1 10.6 12 2 1 13 13 13 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGO25120.1 - 0.00013 22.2 25.1 12 6.5 0.1 11.3 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO25120.1 - 0.0074 16.0 25.1 1.7 8.6 0.1 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO25120.1 - 0.32 10.9 4.5 4 7.3 0.1 4.4 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat GST_N_3 PF13417.1 EGO25121.1 - 6.9e-12 45.4 0.0 2.3e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO25121.1 - 5.6e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO25121.1 - 4e-05 23.7 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO25121.1 - 0.0042 17.0 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO25121.1 - 0.06 13.2 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EGO25122.1 - 1.3e-10 41.4 0.1 2.4e-10 40.5 0.1 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LSM PF01423.17 EGO25124.1 - 2.1e-13 49.5 0.2 2.9e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO25124.1 - 0.00031 20.6 0.0 0.00037 20.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain F-box-like PF12937.2 EGO25125.1 - 7.7e-07 28.7 0.2 1.9e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like DASH_Dad4 PF08650.5 EGO25125.1 - 0.044 13.6 0.1 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad4 F-box-like_2 PF13013.1 EGO25125.1 - 0.05 13.3 0.8 0.18 11.5 0.5 1.9 1 1 0 1 1 1 0 F-box-like domain ADIP PF11559.3 EGO25125.1 - 0.056 13.3 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Acetyltransf_3 PF13302.1 EGO25126.1 - 7.1e-07 29.4 0.0 3.4e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO25126.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family P22_Cro PF14549.1 EGO25126.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro AAA PF00004.24 EGO25127.1 - 1.5e-20 73.7 0.0 4.3e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGO25127.1 - 0.0039 16.9 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EGO25127.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGO25127.1 - 0.018 14.7 0.2 0.085 12.5 0.1 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGO25127.1 - 0.027 13.5 0.0 0.058 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EGO25127.1 - 0.027 14.4 0.1 0.42 10.5 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGO25127.1 - 0.03 14.4 0.0 0.21 11.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EGO25127.1 - 0.098 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EGO25127.1 - 0.18 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 NTPase CHAT PF12770.2 EGO25130.1 - 2.4e-23 82.6 0.0 3.7e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EGO25130.1 - 4.9e-11 42.1 12.8 0.0013 18.3 0.2 7.4 4 2 5 9 9 9 5 TPR repeat TPR_12 PF13424.1 EGO25130.1 - 7.6e-10 38.5 13.9 0.17 11.8 0.0 8.9 5 2 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25130.1 - 0.0088 15.7 5.8 18 5.4 0.1 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25130.1 - 0.011 15.5 6.7 40 4.4 0.2 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25130.1 - 0.066 12.8 14.8 7.3 6.3 0.1 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat Peptidase_M48 PF01435.13 EGO25130.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Sel1 PF08238.7 EGO25130.1 - 0.16 12.6 3.8 10 6.9 0.0 5.5 8 0 0 8 8 8 0 Sel1 repeat TPR_10 PF13374.1 EGO25130.1 - 0.2 11.6 6.8 3.1 7.8 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.22 EGO25132.1 - 3.5e-34 118.0 0.0 6.4e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGO25132.1 - 1.2e-28 100.3 6.6 1.7e-28 99.8 4.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGO25132.1 - 4.5e-07 30.1 0.0 0.011 15.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO25132.1 - 3e-05 24.0 0.1 9.5e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EGO25132.1 - 4e-05 22.9 0.2 0.00057 19.1 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGO25132.1 - 0.00073 19.0 0.1 0.0033 16.9 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGO25132.1 - 0.0024 18.0 0.3 0.02 15.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO25132.1 - 0.0078 15.4 0.0 0.024 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EGO25132.1 - 0.087 11.9 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EGO25132.1 - 0.09 12.7 0.3 1 9.3 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4191 PF13829.1 EGO25132.1 - 0.2 10.7 1.2 0.53 9.3 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) F-box-like PF12937.2 EGO25135.1 - 1.2e-09 37.7 0.7 2.7e-09 36.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO25135.1 - 9.1e-07 28.3 0.7 1.8e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 F-box domain DUF4381 PF14316.1 EGO25138.1 - 0.051 13.6 0.2 0.057 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HEAT PF02985.17 EGO25139.1 - 1.3e-06 28.0 0.4 0.99 9.6 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat Pkinase PF00069.20 EGO25139.1 - 9.2e-05 21.7 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25139.1 - 0.00099 18.2 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO25139.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 EGO25139.1 - 0.12 12.1 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Med14 PF08638.6 EGO25140.1 - 1.4e-50 171.2 0.2 3.2e-50 170.0 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATP_bind_3 PF01171.15 EGO25141.1 - 1.7e-40 138.4 0.0 2.6e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family OmdA PF13376.1 EGO25141.1 - 0.011 15.4 0.7 0.1 12.2 0.2 2.6 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated AAA_22 PF13401.1 EGO25142.1 - 0.02 15.0 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain YqzL PF14006.1 EGO25143.1 - 0.13 12.5 0.1 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 YqzL-like protein Acetyltransf_1 PF00583.19 EGO25145.1 - 1.5e-08 34.5 0.0 6.5e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO25145.1 - 1e-05 25.1 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.1 EGO25145.1 - 0.0017 18.5 0.0 0.0032 17.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGO25145.1 - 0.0043 16.7 0.1 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.1 EGO25145.1 - 0.0068 16.5 0.0 0.11 12.5 0.0 2.4 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO25145.1 - 0.0068 16.5 0.0 0.055 13.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO25145.1 - 0.04 13.7 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO25145.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4598 PF15370.1 EGO25146.1 - 4.5e-15 55.9 2.0 8.3e-15 55.0 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) PP1_inhibitor PF05361.7 EGO25146.1 - 0.084 12.5 0.8 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor Cwf_Cwc_15 PF04889.7 EGO25146.1 - 0.26 10.9 8.6 0.4 10.3 5.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EGO25146.1 - 2.3 6.1 9.2 3 5.7 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGO25146.1 - 2.4 5.9 11.5 0.3 8.9 5.3 1.4 2 0 0 2 2 2 0 Nop14-like family PEPCK_ATP PF01293.15 EGO25147.1 - 9.2e-217 720.1 0.0 1.1e-216 719.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EGO25147.1 - 0.016 14.7 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EGO25147.1 - 0.018 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO25147.1 - 0.081 12.3 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 EGO25149.1 - 2.9e-67 227.2 0.0 3.7e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO25149.1 - 0.0012 18.8 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO25149.1 - 0.0028 16.5 0.1 0.0065 15.3 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO25149.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EGO25149.1 - 0.03 14.2 0.0 0.18 11.6 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO25149.1 - 0.03 12.9 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EGO25149.1 - 0.08 11.3 0.0 0.18 10.2 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGO25149.1 - 0.095 13.1 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sar8_2 PF03058.9 EGO25150.1 - 0.077 13.3 0.7 0.2 12.0 0.5 1.7 1 0 0 1 1 1 0 Sar8.2 family Retrotrans_gag PF03732.12 EGO25151.1 - 1.4e-06 28.2 2.3 1.4e-06 28.2 1.6 2.6 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO25151.1 - 1.3e-05 24.7 1.5 2.9e-05 23.7 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO25151.1 - 0.00023 20.9 5.5 0.00038 20.2 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO25151.1 - 5.7 6.5 7.0 2.7 7.5 2.8 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger FAD_binding_3 PF01494.14 EGO25152.1 - 3.7e-68 230.1 0.0 4.7e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO25152.1 - 0.0014 18.6 0.1 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO25152.1 - 0.0026 16.6 0.1 0.0057 15.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO25152.1 - 0.0098 15.0 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EGO25152.1 - 0.043 12.4 0.0 0.063 11.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGO25152.1 - 0.054 13.3 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO25152.1 - 0.057 11.8 0.0 0.1 11.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGO25152.1 - 0.058 13.8 0.1 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EGO25152.1 - 0.1 12.7 0.2 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Self-incomp_S1 PF05938.6 EGO25153.1 - 0.054 13.6 0.6 0.062 13.4 0.4 1.0 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 DEAD PF00270.24 EGO25154.1 - 3.7e-19 68.8 0.0 1.6e-16 60.3 0.0 3.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO25154.1 - 6.1e-10 38.8 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO25154.1 - 1.8e-05 24.6 0.0 7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGO25154.1 - 0.0095 14.7 0.0 0.023 13.4 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Yae1_N PF09811.4 EGO25156.1 - 0.0061 16.0 1.7 0.033 13.6 0.2 1.9 1 1 1 2 2 2 1 Essential protein Yae1, N terminal Peptidase_M19 PF01244.16 EGO25157.1 - 2.6e-102 342.0 0.0 3.3e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FAD_binding_2 PF00890.19 EGO25158.1 - 6.9e-89 298.5 0.5 8.3e-89 298.3 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EGO25158.1 - 6.3e-22 77.1 0.0 1.4e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EGO25158.1 - 3.8e-13 49.0 0.1 1e-09 37.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO25158.1 - 1.7e-11 44.3 0.0 2.9e-09 37.0 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO25158.1 - 2.9e-10 40.0 0.8 3e-09 36.7 0.1 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO25158.1 - 3.6e-08 32.9 2.3 6e-08 32.1 1.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO25158.1 - 3.5e-06 27.2 0.6 1.3e-05 25.3 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO25158.1 - 7.8e-06 25.1 1.8 1.9e-05 23.8 1.3 1.7 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO25158.1 - 1.9e-05 23.3 4.5 8.6e-05 21.1 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 EGO25158.1 - 3.9e-05 22.6 3.4 9.8e-05 21.3 0.8 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EGO25158.1 - 5.7e-05 22.3 1.7 0.0058 15.7 0.6 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EGO25158.1 - 0.0025 16.9 0.3 0.0049 15.9 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EGO25158.1 - 0.0025 18.2 0.9 0.047 14.0 0.2 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO25158.1 - 0.0049 15.8 0.3 0.028 13.3 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGO25158.1 - 0.0066 16.2 0.2 0.066 12.9 0.1 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EGO25158.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EGO25158.1 - 0.059 12.9 0.4 0.13 11.7 0.3 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EGO25158.1 - 0.11 12.1 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_18 PF13238.1 EGO25159.1 - 1.5e-08 34.9 0.1 1.1e-07 32.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO25159.1 - 3.6e-07 31.0 0.0 6e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EGO25159.1 - 0.00061 19.4 0.1 0.0041 16.7 0.1 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EGO25159.1 - 0.0013 18.6 0.0 0.0053 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO25159.1 - 0.0049 16.0 0.2 0.013 14.5 0.0 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EGO25159.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EGO25159.1 - 0.069 12.3 0.1 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 G-alpha PF00503.15 EGO25159.1 - 0.13 10.9 0.0 0.27 9.8 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit 6PF2K PF01591.13 EGO25159.1 - 0.19 10.7 0.3 0.4 9.7 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF883 PF05957.8 EGO25160.1 - 0.0033 17.7 23.4 0.051 13.9 5.6 2.7 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGO25160.1 - 0.033 13.7 9.0 0.053 13.0 6.3 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain LEA_4 PF02987.11 EGO25160.1 - 0.12 12.2 37.2 0.17 11.7 0.7 5.1 3 1 2 5 5 5 0 Late embryogenesis abundant protein Sod_Fe_C PF02777.13 EGO25160.1 - 0.13 12.1 1.4 0.18 11.6 0.4 1.7 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain YlqD PF11068.3 EGO25160.1 - 0.55 10.2 12.0 0.068 13.2 3.9 2.2 2 1 1 3 3 3 0 YlqD protein ApoO PF09769.4 EGO25160.1 - 0.67 9.6 4.4 8.1 6.1 0.2 2.2 1 1 1 2 2 2 0 Apolipoprotein O YtxH PF12732.2 EGO25160.1 - 1.5 9.2 25.5 1.5e+04 -6.4 17.7 3.6 1 1 0 1 1 1 0 YtxH-like protein DUF3584 PF12128.3 EGO25160.1 - 5.7 4.1 16.9 5.9 4.0 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2580 PF10824.3 EGO25160.1 - 6.3 7.2 11.9 1.2 9.4 4.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2580) NAGLU PF05089.7 EGO25161.1 - 4e-124 413.7 7.4 5.7e-124 413.2 5.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EGO25161.1 - 1.2e-60 205.2 2.8 1.6e-60 204.7 1.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EGO25161.1 - 5.3e-14 51.6 0.0 9.5e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain APG5 PF04106.7 EGO25162.1 - 2.3e-47 161.0 0.0 2.9e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Endonuc-EcoRV PF09233.6 EGO25162.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Restriction endonuclease EcoRV Fungal_trans PF04082.13 EGO25163.1 - 1.3e-06 27.4 0.2 2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPT PF03151.11 EGO25164.1 - 2.1e-30 105.4 8.0 2.1e-30 105.4 5.5 2.4 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EGO25164.1 - 1.7e-07 30.4 16.6 3e-07 29.6 11.5 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO25164.1 - 3.8e-06 26.9 32.4 0.0015 18.5 8.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGO25164.1 - 0.49 10.6 28.4 0.25 11.5 4.1 3.0 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF4212 PF13937.1 EGO25164.1 - 8.3 6.4 11.1 27 4.8 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Med31 PF05669.7 EGO25165.1 - 8.2e-36 121.8 5.9 1.1e-35 121.4 4.1 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 EGO25165.1 - 0.48 10.0 3.3 7.6 6.2 0.1 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat Peptidase_C12 PF01088.16 EGO25166.1 - 1e-54 184.9 0.0 1.7e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Aldo_ket_red PF00248.16 EGO25167.1 - 7.5e-53 179.1 0.0 9.4e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Adeno_PVIII PF01310.13 EGO25167.1 - 0.067 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Sugar_tr PF00083.19 EGO25168.1 - 1.1e-76 258.2 26.4 1.3e-76 258.0 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO25168.1 - 1.6e-18 66.5 46.3 1e-11 44.1 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGO25168.1 - 0.13 12.2 11.5 0.061 13.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) NIF3 PF01784.13 EGO25169.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) NTP_transferase PF00483.18 EGO25170.1 - 1.8e-42 145.3 0.0 3.3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGO25170.1 - 1.6e-07 31.5 0.1 3.9e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 EGO25170.1 - 0.00025 20.6 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 EGO25170.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DivIC PF04977.10 EGO25170.1 - 0.099 12.1 1.7 0.1 12.0 0.3 1.6 2 0 0 2 2 2 0 Septum formation initiator UPF0449 PF15136.1 EGO25170.1 - 0.12 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 IncA PF04156.9 EGO25170.1 - 0.12 11.9 0.3 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 IncA protein FAD_binding_3 PF01494.14 EGO25171.1 - 2.4e-72 243.9 0.0 3e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EGO25171.1 - 2.8e-05 23.1 0.4 2.8e-05 23.1 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO25171.1 - 0.0002 21.2 1.0 0.00057 19.8 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO25171.1 - 0.00024 19.7 0.1 0.00055 18.5 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO25171.1 - 0.00027 20.9 0.7 0.00079 19.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO25171.1 - 0.00031 19.9 0.0 0.00066 18.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EGO25171.1 - 0.00048 19.3 0.2 0.0024 17.0 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO25171.1 - 0.0017 17.0 0.0 0.0027 16.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGO25171.1 - 0.0046 17.0 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO25171.1 - 0.014 14.2 0.3 0.034 13.0 0.2 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EGO25171.1 - 0.016 14.1 0.2 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGO25171.1 - 0.066 12.1 0.2 0.12 11.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EGO25171.1 - 0.068 13.5 0.7 0.78 10.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGO25171.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EGO25172.1 - 7.1e-72 242.4 0.0 9.3e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EGO25172.1 - 0.00016 20.4 0.0 0.00023 19.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EGO25172.1 - 0.00023 21.1 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO25172.1 - 0.00049 19.0 0.0 0.00077 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO25172.1 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGO25172.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO25172.1 - 0.014 13.8 0.0 0.029 12.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGO25172.1 - 0.017 15.4 0.1 0.058 13.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO25172.1 - 0.023 13.7 0.1 0.064 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.19 EGO25172.1 - 0.048 12.5 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGO25172.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGO25172.1 - 0.14 11.9 0.1 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Rhodanese PF00581.15 EGO25173.1 - 2.4e-20 72.9 0.0 6.9e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Rb_C PF08934.5 EGO25173.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Rb C-terminal domain AA_permease PF00324.16 EGO25175.1 - 2.2e-110 369.2 42.5 2.5e-110 369.0 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO25175.1 - 6.7e-32 110.5 51.4 8.1e-32 110.2 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.14 EGO25176.1 - 3.4e-66 223.7 0.0 4.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO25176.1 - 0.001 18.2 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGO25176.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EGO25176.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGO25176.1 - 0.039 12.5 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RhoGAP PF00620.22 EGO25178.1 - 1e-30 106.3 0.0 2.1e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EGO25178.1 - 6.9e-29 100.1 0.1 2.1e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 MyTH4 domain Pheromone PF08015.6 EGO25179.1 - 1.5 9.7 6.8 2.8 8.8 4.7 1.4 1 1 0 1 1 1 0 Fungal mating-type pheromone NAD_binding_2 PF03446.10 EGO25180.1 - 2.9e-09 36.9 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGO25180.1 - 2.3e-06 27.9 0.0 4.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EGO25180.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EGO25180.1 - 0.0029 16.7 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EGO25180.1 - 0.0043 16.7 0.1 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.11 EGO25180.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EGO25180.1 - 0.026 14.1 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nitro_FeMo-Co PF02579.12 EGO25180.1 - 0.08 13.0 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor ThiF PF00899.16 EGO25180.1 - 0.15 11.8 0.6 0.26 11.0 0.4 1.6 1 1 0 1 1 1 0 ThiF family Hydrolase_6 PF13344.1 EGO25182.1 - 5.3e-24 84.0 0.0 9.2e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO25182.1 - 1.3e-20 72.8 0.0 7.5e-20 70.4 0.0 2.3 2 1 1 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO25182.1 - 2.4e-05 24.8 0.0 0.00035 21.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO25182.1 - 4.8e-05 23.6 0.0 0.014 15.6 0.0 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase COP23 PF14218.1 EGO25182.1 - 0.094 12.2 0.0 6.7 6.2 0.0 2.3 1 1 1 2 2 2 0 Circadian oscillating protein COP23 Fungal_trans PF04082.13 EGO25183.1 - 1.2e-12 47.2 1.0 2e-12 46.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO25183.1 - 6e-09 35.6 8.5 1.7e-08 34.2 5.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EGO25183.1 - 7.9e-08 32.2 13.6 0.0006 19.9 1.7 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO25183.1 - 3e-07 30.3 2.1 3e-07 30.3 1.5 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO25183.1 - 3.2e-05 23.9 3.1 3.2e-05 23.9 2.2 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO25183.1 - 0.0065 16.3 2.1 0.0065 16.3 1.5 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO25183.1 - 0.0097 16.0 3.0 0.43 10.7 0.4 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF218 PF02698.12 EGO25185.1 - 0.0015 18.0 0.1 0.0068 15.9 0.0 1.9 1 1 0 1 1 1 1 DUF218 domain AF-4 PF05110.8 EGO25186.1 - 0.46 8.3 11.2 0.8 7.4 7.7 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ECH PF00378.15 EGO25187.1 - 4.7e-78 261.6 0.2 5.7e-78 261.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGO25187.1 - 0.0021 18.1 0.1 0.0046 17.0 0.0 1.6 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 EGO25187.1 - 0.0065 16.2 0.1 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 DUF2760 PF10816.3 EGO25187.1 - 0.14 11.6 0.1 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) Ank_2 PF12796.2 EGO25188.1 - 0.041 14.2 0.0 0.049 13.9 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF817 PF05675.7 EGO25188.1 - 0.066 12.6 0.2 0.068 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF817) Ank PF00023.25 EGO25188.1 - 0.14 12.0 0.1 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat YCII PF03795.9 EGO25189.1 - 1.2e-07 31.8 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain CO_deh_flav_C PF03450.12 EGO25189.1 - 0.13 12.1 0.1 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Asparaginase_2 PF01112.13 EGO25190.1 - 6.5e-52 176.2 0.0 2.1e-37 128.5 0.0 2.3 2 1 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.16 EGO25190.1 - 0.13 10.7 0.0 0.22 9.9 0.0 1.4 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Pex24p PF06398.6 EGO25191.1 - 4.3e-24 84.9 10.1 6.6e-23 81.0 1.7 2.9 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Mannosyl_trans2 PF04188.8 EGO25192.1 - 6.8e-61 206.5 28.9 8.6e-61 206.1 20.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3712 PF12505.3 EGO25193.1 - 8.1e-101 332.8 71.6 4.9e-26 91.2 0.3 10.7 10 1 1 11 11 11 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EGO25193.1 - 1.9e-10 41.0 26.4 0.0014 18.9 0.2 8.9 9 0 0 9 9 9 4 Late embryogenesis abundant protein TC1 PF15063.1 EGO25193.1 - 0.044 13.3 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Thyroid cancer protein 1 p450 PF00067.17 EGO25197.1 - 6.6e-78 262.2 0.0 7.7e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO25198.1 - 4e-73 246.5 0.0 4.9e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO25199.1 - 2.1e-65 221.0 0.0 9.2e-56 189.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MOZART1 PF12554.3 EGO25199.1 - 0.11 11.9 0.3 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated TPR_11 PF13414.1 EGO25201.1 - 9e-27 92.5 16.2 0.00011 21.7 0.0 8.2 8 0 0 8 8 8 5 TPR repeat TPR_2 PF07719.12 EGO25201.1 - 2.9e-17 61.1 18.9 0.017 15.0 0.7 11.8 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGO25201.1 - 2.9e-16 59.5 13.5 0.00022 21.4 0.1 8.0 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25201.1 - 2.4e-14 52.9 28.8 1.2e-06 28.3 0.3 9.2 8 3 2 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25201.1 - 4.7e-14 51.0 1.9 1.2 9.0 0.0 9.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO25201.1 - 5.9e-14 52.2 21.2 4.3e-05 24.0 0.1 7.6 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25201.1 - 2.1e-12 46.0 12.4 0.044 13.4 0.0 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25201.1 - 8.8e-12 44.5 23.6 0.004 17.6 0.1 11.0 10 2 2 12 12 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO25201.1 - 3.8e-11 42.6 2.2 0.00028 21.1 0.0 8.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25201.1 - 3.2e-08 33.1 9.1 2.2 8.6 0.0 8.0 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO25201.1 - 8.3e-07 28.3 17.8 0.082 12.7 0.0 8.0 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_20 PF14561.1 EGO25201.1 - 8.8e-05 22.5 5.1 0.009 16.1 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EGO25201.1 - 0.00031 20.9 0.7 0.32 11.2 0.1 3.0 2 0 0 2 2 2 2 Alkyl sulfatase dimerisation TPR_9 PF13371.1 EGO25201.1 - 0.0025 17.6 18.0 0.029 14.2 0.2 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat Vps39_1 PF10366.4 EGO25201.1 - 0.017 15.1 2.5 2.2 8.3 0.7 3.7 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Apc5 PF12862.2 EGO25201.1 - 0.029 14.2 1.1 11 5.8 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 SNAP PF14938.1 EGO25201.1 - 0.045 12.9 5.2 0.17 11.0 0.1 3.2 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP Chitin_synth_2 PF03142.10 EGO25202.1 - 3.2e-228 758.4 1.3 3.5e-207 688.9 0.3 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO25202.1 - 8.5e-17 61.4 6.7 8.5e-17 61.4 4.7 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO25202.1 - 5.1e-16 59.1 0.0 8.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EGO25202.1 - 7.5e-06 25.6 0.0 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EGO25202.1 - 8.9e-05 21.8 0.1 0.002 17.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGO25202.1 - 0.2 11.3 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.15 EGO25203.1 - 1.4e-05 24.7 1.7 2.4e-05 23.9 0.1 2.0 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO25203.1 - 0.00044 19.6 0.3 0.0023 17.2 0.2 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EGO25203.1 - 0.0018 17.7 0.8 0.0039 16.6 0.2 1.7 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EGO25203.1 - 0.085 13.0 2.0 0.095 12.9 0.1 1.9 3 0 0 3 3 3 0 Tyrosine phosphatase family Dus PF01207.12 EGO25204.1 - 3.2e-70 236.3 0.0 3.9e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EGO25204.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.12 EGO25204.1 - 0.00023 20.8 0.0 0.0041 16.7 0.0 2.2 1 1 1 2 2 2 1 SOR/SNZ family His_biosynth PF00977.16 EGO25204.1 - 0.0038 16.5 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 EGO25204.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.20 EGO25204.1 - 0.05 12.4 0.1 0.077 11.8 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Con-6 PF10346.4 EGO25205.1 - 9.4e-42 140.1 6.0 2.9e-13 48.9 0.1 3.6 3 0 0 3 3 3 3 Conidiation protein 6 DUF3437 PF11919.3 EGO25205.1 - 1e-27 95.6 0.0 3.5e-27 93.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EGO25205.1 - 1.5e-09 37.1 4.2 0.08 13.0 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EGO25205.1 - 9.4e-07 29.0 5.1 0.061 13.6 0.0 6.4 9 0 0 9 9 9 2 HEAT repeats SpoIIIAH PF12685.2 EGO25205.1 - 0.0038 16.7 0.2 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 SpoIIIAH-like protein Dynamitin PF04912.9 EGO25206.1 - 4.6e-15 55.3 0.0 7.1e-15 54.6 0.0 1.3 1 1 0 1 1 1 1 Dynamitin SlyX PF04102.7 EGO25206.1 - 0.0018 18.5 2.5 0.82 10.0 0.2 2.6 3 0 0 3 3 3 2 SlyX PLU-1 PF08429.6 EGO25206.1 - 0.097 11.5 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 PLU-1-like protein Peptidase_M22 PF00814.20 EGO25207.1 - 2.2e-68 230.6 0.0 3e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family HbrB PF08539.6 EGO25208.1 - 3e-33 114.9 0.0 4.9e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 HbrB-like ATPase-cat_bd PF12156.3 EGO25209.1 - 0.029 14.8 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-SNAP50_C PF12251.3 EGO25211.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal ATP-sulfurylase PF01747.12 EGO25212.1 - 1.2e-86 289.4 0.1 1.8e-86 288.9 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EGO25212.1 - 4.2e-51 172.5 0.0 6.9e-51 171.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EGO25212.1 - 1.3e-48 164.5 0.0 2e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 EGO25212.1 - 0.054 12.7 0.0 0.11 11.6 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Amidohydro_4 PF13147.1 EGO25215.1 - 4e-11 43.4 5.5 1.3e-10 41.7 2.0 2.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EGO25215.1 - 6.8e-09 35.4 1.8 1.1e-07 31.5 0.0 3.1 3 1 0 3 3 3 1 Amidohydrolase DUF4381 PF14316.1 EGO25216.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Amidohydro_4 PF13147.1 EGO25219.1 - 1.8e-15 57.7 6.1 1.8e-15 57.7 4.2 2.9 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EGO25219.1 - 3.4e-11 42.7 3.1 2.9e-09 36.6 0.2 3.3 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO25219.1 - 0.052 13.2 0.2 17 4.9 0.0 3.6 4 0 0 4 4 4 0 Amidohydrolase family ERO1 PF04137.10 EGO25220.1 - 1.2e-13 50.7 0.0 1.2e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Aldo_ket_red PF00248.16 EGO25221.1 - 1.8e-46 158.2 0.0 2.2e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CHCC PF10276.4 EGO25222.1 - 8.7e-17 60.6 2.3 1.3e-16 60.1 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain EHN PF06441.7 EGO25223.1 - 2.4e-33 114.4 0.7 3.5e-32 110.6 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGO25223.1 - 8.8e-09 35.5 0.2 2.5e-08 34.1 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO25223.1 - 0.00014 21.5 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 EGO25224.1 - 2.6e-50 171.3 0.0 2.9e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P68HR PF08061.6 EGO25224.1 - 0.053 13.2 0.3 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 P68HR (NUC004) repeat Abhydrolase_6 PF12697.2 EGO25225.1 - 9.7e-22 77.9 0.0 3.7e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO25225.1 - 1.3e-15 57.6 0.0 4.7e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO25225.1 - 8.9e-08 32.0 0.0 2.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EGO25225.1 - 0.064 13.1 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus MmgE_PrpD PF03972.9 EGO25226.1 - 5.4e-157 522.5 0.0 6.6e-157 522.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RNase_H2-Ydr279 PF09468.5 EGO25228.1 - 3.1e-46 157.9 0.1 4.1e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Slu7 PF11708.3 EGO25229.1 - 9.3e-82 274.3 14.4 9.3e-82 274.3 10.0 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EGO25229.1 - 0.051 13.2 0.7 0.1 12.2 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle SNF2_N PF00176.18 EGO25230.1 - 1.1e-67 227.9 0.4 2.2e-67 226.9 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EGO25230.1 - 4.4e-26 91.0 2.0 6.8e-26 90.4 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EGO25230.1 - 5.5e-21 73.9 3.9 2.3e-15 55.9 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EGO25230.1 - 4.3e-14 52.1 0.0 9.2e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO25230.1 - 1.2e-06 28.5 0.1 3.9e-05 23.5 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TBP PF00352.16 EGO25230.1 - 0.0079 15.5 0.0 0.022 14.1 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) Myb_DNA-binding PF00249.26 EGO25230.1 - 0.036 14.1 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain FlhC PF05280.6 EGO25230.1 - 0.044 13.2 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) AAA_22 PF13401.1 EGO25230.1 - 0.077 13.1 0.2 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Asparaginase_2 PF01112.13 EGO25231.1 - 2.3e-43 148.1 1.7 3.1e-43 147.6 1.2 1.1 1 0 0 1 1 1 1 Asparaginase NAD_binding_4 PF07993.7 EGO25232.1 - 1.9e-36 125.2 0.0 2.8e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO25232.1 - 4.2e-25 88.0 0.3 3.4e-19 68.5 0.1 2.9 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EGO25232.1 - 2.7e-10 40.3 0.0 6.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGO25232.1 - 4.3e-10 39.4 0.0 1.5e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO25232.1 - 0.013 15.3 0.4 0.055 13.3 0.3 2.0 1 1 0 1 1 1 0 short chain dehydrogenase WD40_alt PF14077.1 EGO25233.1 - 0.0037 16.8 0.1 0.0091 15.6 0.1 1.6 1 0 0 1 1 1 1 Alternative WD40 repeat motif IF-2B PF01008.12 EGO25234.1 - 8.7e-55 185.6 0.0 1.1e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.8 EGO25235.1 - 8e-31 107.2 0.0 3.8e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO25235.1 - 0.069 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) TPR_11 PF13414.1 EGO25237.1 - 1.7e-18 66.0 8.4 6.1e-10 38.6 1.3 3.9 2 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EGO25237.1 - 8.1e-17 60.0 5.6 0.0018 17.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25237.1 - 1.8e-15 55.7 11.8 0.00097 19.1 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25237.1 - 6.6e-14 50.6 11.4 0.0067 16.2 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25237.1 - 9.4e-12 44.4 13.1 0.0047 17.4 0.3 5.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGO25237.1 - 2.3e-11 43.8 11.0 1.4e-07 31.7 0.5 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25237.1 - 3.7e-10 39.6 9.9 9.6e-05 22.2 1.5 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO25237.1 - 7.2e-09 36.0 11.5 8.3e-06 26.3 1.7 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25237.1 - 1.1e-06 28.0 3.7 0.034 13.9 0.7 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGO25237.1 - 7e-06 26.0 6.6 0.053 13.6 0.1 4.0 2 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO25237.1 - 0.00013 21.9 4.3 0.0015 18.6 1.4 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGO25237.1 - 0.0011 18.7 7.1 0.19 11.6 0.4 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO25237.1 - 0.024 14.4 8.8 3.2 7.7 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3507 PF12015.3 EGO25237.1 - 0.07 12.6 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3507) MIT PF04212.13 EGO25237.1 - 0.19 11.5 4.5 0.64 9.9 0.3 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EGO25237.1 - 0.93 10.0 4.0 70 4.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat APC_CDC26 PF10471.4 EGO25238.1 - 0.0023 18.6 4.4 0.0034 18.0 3.0 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 HTH_37 PF13744.1 EGO25238.1 - 0.04 13.7 2.1 0.089 12.6 0.6 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain DUF382 PF04037.8 EGO25238.1 - 0.042 13.6 2.3 0.042 13.6 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF382) ATP-synt_E PF05680.7 EGO25238.1 - 0.34 10.8 2.3 0.5 10.3 1.5 1.4 1 1 0 1 1 1 0 ATP synthase E chain PRA1 PF03208.14 EGO25239.1 - 1.4e-37 128.4 0.4 1.7e-37 128.1 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein Endotoxin_N PF03945.9 EGO25239.1 - 0.16 11.3 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Zn_clus PF00172.13 EGO25240.1 - 5.5e-05 22.9 11.9 9.3e-05 22.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EGO25240.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold Methyltransf_26 PF13659.1 EGO25241.1 - 2.9e-13 49.8 0.0 3.1e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO25241.1 - 1.5e-07 31.9 0.0 2.7e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO25241.1 - 1.9e-07 30.8 0.0 1.1e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO25241.1 - 0.00057 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO25241.1 - 0.0028 16.8 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EGO25241.1 - 0.0091 15.7 0.0 0.022 14.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGO25241.1 - 0.068 12.5 0.1 1.8 7.9 0.1 2.7 2 1 0 2 2 2 0 Conserved hypothetical protein 95 AviRa PF11599.3 EGO25241.1 - 0.08 11.9 0.0 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 RRNA methyltransferase AviRa MTS PF05175.9 EGO25241.1 - 0.082 12.2 0.0 0.35 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.13 EGO25241.1 - 0.17 11.4 0.2 1.1 8.7 0.1 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Allantoicase PF03561.10 EGO25242.1 - 3.4e-90 299.3 0.0 1.6e-44 151.0 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 EGO25242.1 - 1.6e-45 154.3 0.0 2.4e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase BRE1 PF08647.6 EGO25243.1 - 5e-17 61.6 6.3 5e-17 61.6 4.4 8.4 7 3 2 9 9 8 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EGO25243.1 - 1.2e-08 34.8 11.3 2.7e-08 33.6 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO25243.1 - 9.1e-08 31.6 9.6 1.8e-07 30.7 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO25243.1 - 1.2e-06 28.0 12.0 2.5e-06 27.0 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25243.1 - 2.2e-06 27.3 11.6 4.4e-06 26.3 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO25243.1 - 6.1e-06 25.9 9.6 1.1e-05 25.0 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EGO25243.1 - 0.00055 19.6 4.1 0.0012 18.6 2.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGO25243.1 - 0.012 15.6 4.6 0.04 14.0 3.2 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger Cep57_MT_bd PF06657.8 EGO25243.1 - 0.018 14.9 3.5 0.018 14.9 2.5 6.8 8 2 0 8 8 7 0 Centrosome microtubule-binding domain of Cep57 zf-RING_UBOX PF13445.1 EGO25243.1 - 0.042 13.5 7.1 0.12 12.1 4.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DMPK_coil PF08826.5 EGO25243.1 - 0.11 12.3 0.1 0.11 12.3 0.0 9.4 10 1 0 10 10 10 0 DMPK coiled coil domain like zf-C3HC4_4 PF15227.1 EGO25243.1 - 0.12 12.2 7.6 0.24 11.3 5.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2_6 PF13912.1 EGO25243.1 - 0.15 11.9 4.3 2 8.4 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger NPV_P10 PF05531.7 EGO25243.1 - 0.21 11.8 0.1 0.21 11.8 0.1 5.8 7 2 0 7 7 5 0 Nucleopolyhedrovirus P10 protein DUF1272 PF06906.6 EGO25243.1 - 0.43 10.4 6.6 1 9.2 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Reo_sigmaC PF04582.7 EGO25243.1 - 0.45 9.6 25.2 0.008 15.3 1.9 5.7 1 1 4 6 6 6 0 Reovirus sigma C capsid protein IncA PF04156.9 EGO25243.1 - 1.1 8.8 78.5 0.083 12.4 8.4 6.9 1 1 6 7 7 7 0 IncA protein zf-RING_4 PF14570.1 EGO25243.1 - 2.8 7.5 10.1 6.4 6.4 6.0 2.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Ribosomal_S9 PF00380.14 EGO25244.1 - 3.3e-33 114.4 0.0 1.4e-32 112.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S9/S16 CASP_C PF08172.7 EGO25245.1 - 8.3e-25 87.2 2.7 8.3e-25 87.2 1.9 3.2 2 1 0 2 2 2 1 CASP C terminal IncA PF04156.9 EGO25245.1 - 0.0044 16.6 32.2 0.23 11.0 12.3 3.1 3 0 0 3 3 3 3 IncA protein DivIVA PF05103.8 EGO25245.1 - 0.015 15.3 7.5 0.015 15.3 5.2 4.5 3 2 1 4 4 4 0 DivIVA protein DivIC PF04977.10 EGO25245.1 - 0.021 14.3 27.0 0.027 13.9 0.4 5.3 3 1 2 5 5 5 0 Septum formation initiator CtIP_N PF10482.4 EGO25245.1 - 0.11 12.2 0.1 0.11 12.2 0.1 3.3 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain FlaC_arch PF05377.6 EGO25245.1 - 0.99 9.3 19.5 0.69 9.8 0.1 4.3 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) ArdA PF07275.6 EGO25245.1 - 1.6 8.9 5.1 0.88 9.7 0.7 2.3 2 1 0 2 2 2 0 Antirestriction protein (ArdA) bZIP_2 PF07716.10 EGO25245.1 - 1.7 8.5 30.1 1 9.2 0.2 5.8 5 1 1 6 6 6 0 Basic region leucine zipper LZ_Tnp_IS66 PF13007.2 EGO25245.1 - 2.8 8.6 9.5 0.14 12.8 0.8 3.0 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain DUF2935 PF11155.3 EGO25245.1 - 3 7.9 10.5 9.6 6.3 1.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF972 PF06156.8 EGO25245.1 - 3.8 7.9 21.4 31 4.9 0.8 4.3 3 1 0 3 3 3 0 Protein of unknown function (DUF972) WD40_alt PF14077.1 EGO25245.1 - 4 7.1 12.8 1.9 8.1 0.4 4.0 4 1 0 4 4 4 0 Alternative WD40 repeat motif TBPIP PF07106.8 EGO25245.1 - 5.9 6.4 24.9 2.1 7.8 7.6 3.8 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HAUS6_N PF14661.1 EGO25245.1 - 7.9 5.7 20.4 0.75 9.1 0.3 3.1 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus CASP_C PF08172.7 EGO25246.1 - 1.1e-06 27.8 1.2 9.9e-06 24.7 0.0 2.2 2 1 1 3 3 3 2 CASP C terminal IPPT PF01715.12 EGO25247.1 - 0.055 12.4 0.1 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 IPP transferase RVP_2 PF08284.6 EGO25248.1 - 6e-05 23.0 0.0 0.0024 17.7 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO25248.1 - 0.0014 19.0 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO25248.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MOZ_SAS PF01853.13 EGO25249.1 - 2.9e-84 281.0 0.6 4.2e-84 280.5 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family HTH_Mga PF08280.6 EGO25249.1 - 0.0003 20.4 0.9 0.00075 19.2 0.6 1.6 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_1 PF00583.19 EGO25249.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HTH_11 PF08279.7 EGO25249.1 - 0.12 12.0 0.5 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 HTH domain Acetyltransf_7 PF13508.1 EGO25249.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CCDC74_C PF14917.1 EGO25256.1 - 0.0068 16.4 3.2 0.0068 16.4 2.2 1.8 1 1 1 2 2 2 1 Coiled coil protein 74, C terminal Atg14 PF10186.4 EGO25256.1 - 0.0074 15.2 8.6 0.0081 15.1 5.9 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EGO25256.1 - 0.0097 14.6 8.6 0.013 14.2 5.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EGO25256.1 - 0.015 15.0 12.5 0.16 11.7 1.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF98 PF01947.11 EGO25256.1 - 0.028 14.1 0.7 0.046 13.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF98) Fib_alpha PF08702.5 EGO25256.1 - 0.029 14.4 8.8 0.089 12.9 5.3 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_bind_2 PF10133.4 EGO25256.1 - 0.034 14.1 0.1 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Predicted RNA-binding protein AAA_13 PF13166.1 EGO25256.1 - 0.093 11.1 5.9 0.1 11.0 4.1 1.1 1 0 0 1 1 1 0 AAA domain GLE1 PF07817.8 EGO25256.1 - 0.22 10.4 3.2 0.3 10.0 2.3 1.2 1 0 0 1 1 1 0 GLE1-like protein Kinesin-relat_1 PF12711.2 EGO25256.1 - 0.28 11.5 6.0 1.1 9.7 3.8 1.9 1 1 1 2 2 2 0 Kinesin motor ATG16 PF08614.6 EGO25256.1 - 1.4 8.7 13.1 2 8.2 9.1 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Pkinase PF00069.20 EGO25259.1 - 9.9e-55 185.4 0.0 2.3e-54 184.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25259.1 - 2.7e-22 79.0 0.0 4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO25259.1 - 4.3e-05 23.3 0.1 6.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO25259.1 - 0.00037 19.8 0.2 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EGO25259.1 - 0.029 13.9 0.1 0.08 12.4 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase NCD2 PF04905.8 EGO25260.1 - 0.12 12.1 0.2 0.14 11.9 0.1 1.0 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Put_Phosphatase PF06888.7 EGO25261.1 - 9.2e-51 172.2 0.0 4.1e-47 160.3 0.0 2.0 1 1 1 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EGO25261.1 - 0.00017 21.8 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO25261.1 - 0.11 12.7 0.1 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BSD PF03909.12 EGO25262.1 - 6.9e-21 73.7 0.0 4.2e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EGO25262.1 - 5.2e-11 42.0 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Retrotrans_gag PF03732.12 EGO25267.1 - 2.7e-07 30.5 1.6 2.7e-07 30.5 1.1 2.2 2 1 0 2 2 2 1 Retrotransposon gag protein Sbi-IV PF11621.3 EGO25267.1 - 0.015 15.4 0.8 0.046 13.8 0.5 1.9 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI V-ATPase_G PF03179.10 EGO25267.1 - 2.1 8.6 9.8 0.19 12.0 1.5 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATG11 PF10377.4 EGO25268.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 11 DUF1891 PF09004.5 EGO25268.1 - 0.29 10.5 1.9 0.3 10.4 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1891) Pkinase PF00069.20 EGO25271.1 - 5.7e-52 176.4 0.0 7.4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25271.1 - 6.7e-35 120.4 0.0 2.5e-33 115.2 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO25271.1 - 7.1e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO25271.1 - 0.00061 19.5 0.1 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGO25271.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Helitron_like_N PF14214.1 EGO25272.1 - 3.8e-11 43.0 0.3 3.2e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Retrotrans_gag PF03732.12 EGO25276.1 - 6e-07 29.4 3.9 6.1e-07 29.4 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein ADH_zinc_N PF00107.21 EGO25277.1 - 4.9e-32 110.2 0.2 7.3e-32 109.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO25277.1 - 4.4e-12 47.0 0.0 8.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO25277.1 - 4.5e-08 32.8 0.0 2.8e-07 30.2 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_A_bac PF01000.21 EGO25278.1 - 4.2e-30 104.1 0.0 7.2e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGO25278.1 - 2.1e-13 49.1 0.0 2.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EGO25278.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 RabGAP-TBC PF00566.13 EGO25279.1 - 9.7e-53 178.8 0.3 9.7e-53 178.8 0.2 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Phage_int_SAM_1 PF02899.12 EGO25279.1 - 0.0092 16.1 0.9 1.2 9.3 0.2 3.2 2 1 1 3 3 3 1 Phage integrase, N-terminal SAM-like domain DivIVA PF05103.8 EGO25279.1 - 0.037 14.0 3.7 0.15 12.1 1.6 2.3 2 0 0 2 2 2 0 DivIVA protein DASH_Dad3 PF08656.5 EGO25279.1 - 0.21 11.2 2.8 0.68 9.6 1.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Cep57_CLD_2 PF14197.1 EGO25279.1 - 1.7 8.6 13.9 0.054 13.4 5.0 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Amidohydro_1 PF01979.15 EGO25280.1 - 1.3e-25 90.8 0.0 3e-24 86.2 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGO25280.1 - 7.2e-24 85.2 0.0 9.4e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGO25280.1 - 7.6e-13 48.0 1.3 2.9e-12 46.2 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO25280.1 - 5.8e-08 32.3 0.1 0.00061 19.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Aminotran_3 PF00202.16 EGO25281.1 - 2.5e-105 352.0 0.0 3e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGO25281.1 - 3.4e-05 22.9 0.0 5.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGO25281.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PTP_N PF12453.3 EGO25281.1 - 0.27 10.8 1.3 0.6 9.7 0.9 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal zf-RING_2 PF13639.1 EGO25282.1 - 2e-13 49.9 4.7 3.3e-13 49.2 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO25282.1 - 1.5e-06 28.2 1.8 3.2e-06 27.1 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO25282.1 - 2.8e-06 26.9 2.0 5e-06 26.1 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGO25282.1 - 4.3e-06 26.4 1.4 7.9e-06 25.6 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGO25282.1 - 5.7e-06 26.2 4.4 1.1e-05 25.3 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO25282.1 - 6.5e-05 22.5 1.4 0.00012 21.6 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGO25282.1 - 0.00022 20.7 2.7 0.00037 20.0 1.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EGO25282.1 - 0.00025 20.6 2.8 0.00047 19.7 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGO25282.1 - 0.0079 16.1 1.8 0.021 14.7 1.2 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EGO25282.1 - 0.014 15.4 2.3 0.026 14.5 1.6 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.1 EGO25282.1 - 1.4 8.5 4.6 4.9 6.7 1.2 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 HSP9_HSP12 PF04119.7 EGO25283.1 - 3.8e-21 74.9 12.1 5.6e-21 74.3 6.3 2.1 2 1 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 EGO25283.1 - 0.055 13.5 7.6 1 9.5 1.6 2.9 1 1 1 2 2 2 0 MT0933-like antitoxin protein Josephin PF02099.12 EGO25284.1 - 1.5e-27 96.1 1.8 8.8e-22 77.4 0.0 3.3 1 1 1 2 2 2 2 Josephin DUF3752 PF12572.3 EGO25284.1 - 0.87 9.6 10.5 0.08 13.0 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) ATG27 PF09451.5 EGO25285.1 - 1.2e-47 162.4 0.0 1.5e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EGO25285.1 - 0.00094 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF1469 PF07332.6 EGO25285.1 - 0.14 11.9 0.2 6.2 6.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) GPI-anchored PF10342.4 EGO25288.1 - 3.4e-09 37.0 0.8 4.7e-09 36.6 0.6 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGO25288.1 - 0.00022 20.7 0.1 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DEAD PF00270.24 EGO25289.1 - 3.6e-36 124.1 0.0 1.9e-35 121.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO25289.1 - 1.5e-20 72.8 0.3 5.5e-20 71.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EGO25289.1 - 1.8e-19 69.2 2.5 1.8e-19 69.2 1.8 2.3 2 0 0 2 2 2 1 DBP10CT (NUC160) domain TGT PF01702.13 EGO25290.1 - 1.3e-75 253.8 0.0 1.6e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase tRNA-synt_1b PF00579.20 EGO25291.1 - 9.2e-10 38.1 0.3 1.4e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EMP70 PF02990.11 EGO25292.1 - 8.9e-185 615.0 0.0 1.2e-184 614.6 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Mig-14 PF07395.6 EGO25293.1 - 0.00056 19.0 0.0 0.00076 18.5 0.0 1.1 1 0 0 1 1 1 1 Mig-14 Abhydrolase_6 PF12697.2 EGO25293.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO25294.1 - 2.9e-14 53.4 0.0 4.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO25294.1 - 1.2e-12 47.9 0.2 4.4e-12 46.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO25294.1 - 0.019 14.6 0.0 0.093 12.4 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO25295.1 - 8.8e-09 35.2 0.0 4.2e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO25295.1 - 1.7e-08 34.6 0.0 2.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO25295.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family CTP_transf_1 PF01148.15 EGO25296.1 - 1.2e-75 254.5 23.8 1.5e-75 254.2 16.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Topoisom_I_N PF02919.10 EGO25297.1 - 6.1e-95 316.5 4.1 6.1e-95 316.5 2.9 3.2 3 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGO25297.1 - 3.8e-87 291.2 7.2 1e-86 289.8 5.0 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGO25297.1 - 7.1e-33 112.0 0.4 2e-32 110.6 0.3 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EGO25297.1 - 0.064 12.4 0.6 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 RolB/RolC glucosidase family NDUF_B12 PF08122.7 EGO25298.1 - 2e-20 72.2 0.9 2.2e-20 72.1 0.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family HAD_2 PF13419.1 EGO25300.1 - 6.5e-29 101.3 0.0 1.1e-28 100.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO25300.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 EGO25300.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) PALP PF00291.20 EGO25301.1 - 5e-75 252.5 0.1 6.4e-75 252.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EGO25301.1 - 3.7e-44 148.2 0.0 9.9e-26 89.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Dscam_C PF12355.3 EGO25302.1 - 0.084 13.1 7.3 0.1 12.9 5.0 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Macoilin PF09726.4 EGO25302.1 - 6.2 4.9 5.8 6.4 4.9 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein CAP_N PF01213.14 EGO25302.1 - 9.2 5.4 8.8 9.8 5.3 6.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Vps8 PF12816.2 EGO25304.1 - 1.6e-67 226.5 0.0 1.4e-63 213.6 0.0 2.4 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 PQQ_3 PF13570.1 EGO25304.1 - 0.0097 16.1 0.1 0.044 14.0 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain Clathrin PF00637.15 EGO25304.1 - 0.08 12.5 0.0 0.48 10.0 0.0 2.2 3 0 0 3 3 3 0 Region in Clathrin and VPS COG2 PF06148.6 EGO25305.1 - 8.8e-29 100.0 7.3 8.9e-29 100.0 2.5 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EGO25305.1 - 4.2e-16 59.1 0.0 1.7e-15 57.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 EGO25305.1 - 0.0009 19.0 0.3 0.0045 16.7 0.2 2.3 1 1 0 1 1 1 1 Vps51/Vps67 IncA PF04156.9 EGO25305.1 - 0.09 12.3 13.9 0.41 10.2 6.2 2.4 1 1 1 2 2 2 0 IncA protein Voltage_CLC PF00654.15 EGO25307.1 - 2.6e-93 312.8 19.9 2.6e-93 312.8 13.8 2.2 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGO25307.1 - 0.0016 18.1 0.1 0.0097 15.6 0.0 2.2 2 0 0 2 2 2 1 CBS domain Cauli_VI PF01693.11 EGO25308.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin LSM PF01423.17 EGO25309.1 - 3.6e-12 45.6 0.3 4.7e-12 45.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO25309.1 - 0.052 13.4 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain E3_binding PF02817.12 EGO25309.1 - 0.068 12.8 0.3 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain DUF1674 PF07896.7 EGO25310.1 - 1.6e-11 44.1 0.7 1.9e-11 44.0 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.13 EGO25312.1 - 1.8e-22 79.5 0.0 2.9e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 EGO25313.1 - 0.00081 19.0 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.1 EGO25314.1 - 6.7e-08 32.8 0.0 8.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO25314.1 - 6.4e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EGO25314.1 - 0.00021 21.2 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3435 PF11917.3 EGO25317.1 - 0.00083 18.1 0.1 0.00095 17.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) BTB PF00651.26 EGO25318.1 - 4.5e-11 42.7 0.0 6.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Apt1 PF10351.4 EGO25318.1 - 0.043 12.6 0.6 0.056 12.2 0.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RhoGAP PF00620.22 EGO25319.1 - 3e-43 147.0 0.1 1e-42 145.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.17 EGO25319.1 - 4e-06 26.4 10.7 6.2e-06 25.8 7.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF972 PF06156.8 EGO25319.1 - 0.023 15.0 2.1 0.023 15.0 1.5 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF4473 PF14747.1 EGO25319.1 - 0.041 14.0 0.1 2.6 8.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Macoilin PF09726.4 EGO25319.1 - 0.043 12.1 11.9 0.0068 14.7 5.5 1.4 1 1 0 1 1 1 0 Transmembrane protein zf-C5HC2 PF02928.11 EGO25319.1 - 0.43 10.6 5.6 0.86 9.7 3.9 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger Prominin PF05478.6 EGO25319.1 - 0.75 7.2 4.3 1.1 6.7 2.6 1.4 1 1 0 1 1 1 0 Prominin DZR PF12773.2 EGO25319.1 - 0.83 9.5 4.0 1.6 8.5 2.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.11 EGO25319.1 - 1.6 8.9 5.7 2.7 8.2 3.9 1.4 1 0 0 1 1 1 0 C1 domain 4HB_MCP_1 PF12729.2 EGO25319.1 - 2.2 7.5 8.3 1.8 7.9 0.1 2.7 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction PHD PF00628.24 EGO25319.1 - 6.4 6.5 9.0 12 5.6 6.3 1.4 1 0 0 1 1 1 0 PHD-finger KTI12 PF08433.5 EGO25320.1 - 1.6e-77 260.3 0.0 1.9e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGO25320.1 - 5.2e-07 29.6 0.0 8.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO25320.1 - 0.0054 17.0 0.0 0.0087 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF3419 PF11899.3 EGO25321.1 - 7.2e-127 423.2 0.0 9.5e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_11 PF08241.7 EGO25321.1 - 1.1e-08 35.4 0.0 2.4e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGO25321.1 - 2.3e-08 33.9 0.0 3.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO25321.1 - 4.6e-08 33.4 0.0 1.5e-05 25.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO25321.1 - 2.2e-07 30.2 0.0 8.8e-06 24.9 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGO25321.1 - 1.7e-06 28.5 0.0 3.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO25321.1 - 1.2e-05 24.8 0.0 3.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO25321.1 - 0.00098 19.4 0.0 0.0052 17.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO25321.1 - 0.0048 16.9 0.0 0.096 12.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO25321.1 - 0.14 11.2 0.0 0.32 10.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase HAD_2 PF13419.1 EGO25322.1 - 3.2e-19 69.8 0.0 4.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO25322.1 - 1.1e-09 39.0 0.0 2.6e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO25322.1 - 0.0035 17.0 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EGO25322.1 - 0.011 15.6 0.0 0.69 9.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO25322.1 - 0.13 11.8 0.0 4.2 6.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BRO1 PF03097.13 EGO25323.1 - 2.7e-20 72.4 0.0 3.7e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain HTH_psq PF05225.11 EGO25324.1 - 3.7e-07 29.5 0.1 7.3e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SAP PF02037.22 EGO25324.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 SAP domain HTH_28 PF13518.1 EGO25324.1 - 0.046 13.7 0.1 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1253 PF06862.7 EGO25325.1 - 4.4e-146 486.7 0.0 5.3e-146 486.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Ribosomal_L19e PF01280.15 EGO25326.1 - 0.35 10.6 3.3 0.42 10.3 2.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e Cut8_N PF14482.1 EGO25329.1 - 0.064 13.2 0.5 0.064 13.2 0.4 2.3 2 0 0 2 2 2 0 Cut8 proteasome-binding domain MFS_1 PF07690.11 EGO25330.1 - 5.9e-33 114.0 29.8 9.8e-33 113.3 20.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MARVEL PF01284.18 EGO25330.1 - 2.1 8.1 20.4 1.5 8.6 1.4 3.5 2 2 1 3 3 3 0 Membrane-associating domain CPSF_A PF03178.10 EGO25331.1 - 1e-92 310.6 0.0 4.7e-92 308.5 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EGO25331.1 - 1.4e-79 267.5 0.0 2.1e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term OsmC PF02566.14 EGO25332.1 - 9.7e-13 48.1 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Malate_synthase PF01274.17 EGO25333.1 - 2.5e-196 652.7 0.0 3e-196 652.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EGO25333.1 - 0.028 13.3 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family T2SJ PF11612.3 EGO25333.1 - 0.041 13.6 0.2 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J CHD5 PF04420.9 EGO25334.1 - 1.4e-47 161.3 1.6 2e-47 160.8 1.1 1.2 1 0 0 1 1 1 1 CHD5-like protein Ribosomal_L39 PF00832.15 EGO25335.1 - 1e-22 79.2 9.2 1.2e-22 79.1 6.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein FKBP_C PF00254.23 EGO25336.1 - 6.6e-32 109.4 0.0 7.9e-32 109.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GHMP_kinases_N PF00288.21 EGO25338.1 - 1.4e-12 47.4 0.9 3.9e-12 46.0 0.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO25338.1 - 1.6e-09 37.8 0.0 4.6e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal NFRKB_winged PF14465.1 EGO25338.1 - 0.08 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 NFRKB Winged Helix-like Aa_trans PF01490.13 EGO25339.1 - 7.5e-66 222.2 25.7 9e-66 222.0 17.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fe_hyd_lg_C PF02906.9 EGO25343.1 - 8.5e-57 192.5 0.0 1.1e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.14 EGO25345.1 - 2.7e-17 62.2 0.4 5.8e-17 61.1 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EGO25345.1 - 1.4e-09 38.0 0.2 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Syntaxin FR47 PF08445.5 EGO25346.1 - 1.1e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EGO25346.1 - 0.00044 20.2 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Gly_acyl_tr_C PF08444.5 EGO25346.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_10 PF13673.1 EGO25346.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C1_2 PF03051.10 EGO25348.1 - 1.5e-159 531.2 0.0 1.7e-159 531.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EGO25348.1 - 5.8e-07 29.6 0.0 0.037 13.9 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 EGO25348.1 - 0.009 14.5 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Phage portal protein, lambda family Peptidase_C39_2 PF13529.1 EGO25348.1 - 0.045 14.0 0.1 1.8 8.8 0.0 3.1 1 1 1 2 2 2 0 Peptidase_C39 like family FAD_binding_3 PF01494.14 EGO25349.1 - 1.9e-64 218.0 0.0 6.6e-52 176.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EGO25349.1 - 3.2e-06 26.2 0.1 1.1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO25349.1 - 5.4e-05 23.1 0.6 0.00022 21.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO25349.1 - 5.5e-05 22.3 0.1 0.00011 21.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EGO25349.1 - 0.00012 20.6 0.3 0.0003 19.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGO25349.1 - 0.00032 20.8 0.0 0.00099 19.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO25349.1 - 0.00046 20.1 0.1 0.0025 17.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO25349.1 - 0.00062 20.1 0.3 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO25349.1 - 0.0025 16.7 0.0 0.0061 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO25349.1 - 0.0027 16.6 0.1 0.0042 16.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGO25349.1 - 0.0035 16.4 0.2 0.0066 15.5 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO25349.1 - 0.096 12.4 0.5 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EGO25350.1 - 2.5e-45 154.9 0.7 3e-45 154.7 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO25350.1 - 0.00017 21.5 0.6 0.00047 20.1 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO25350.1 - 0.013 15.5 0.0 5 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.22 EGO25351.1 - 1e-57 191.7 0.0 1.1e-17 63.5 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein SGL PF08450.7 EGO25352.1 - 1.5e-05 24.4 0.2 2.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EGO25352.1 - 0.0003 20.6 0.0 0.003 17.4 0.0 2.6 3 0 0 3 3 3 1 Arylesterase Na_H_Exchanger PF00999.16 EGO25353.1 - 1e-48 165.7 27.4 1.2e-48 165.5 19.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4027 PF13219.1 EGO25353.1 - 0.048 13.0 0.9 0.14 11.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) YrhC PF14143.1 EGO25353.1 - 2.8 7.9 9.8 0.43 10.5 0.4 3.4 3 0 0 3 3 3 0 YrhC-like protein Ssl1 PF04056.9 EGO25355.1 - 1e-70 237.2 0.0 1.4e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EGO25355.1 - 2e-14 53.3 11.1 2e-14 53.3 7.7 3.2 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 EGO25355.1 - 9.8e-12 45.3 0.0 1.6e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EGO25355.1 - 0.0011 18.3 3.6 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 Tcp11 PF05794.8 EGO25356.1 - 1.5e-16 60.1 0.0 5.1e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 T-complex protein 11 Mg_trans_NIPA PF05653.9 EGO25357.1 - 4.6e-18 65.2 11.5 7.7e-10 38.2 0.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EGO25357.1 - 2.7e-05 24.3 7.6 2.7e-05 24.3 5.3 4.7 3 2 1 4 4 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGO25357.1 - 0.00016 21.7 27.0 0.027 14.5 6.5 3.7 3 1 0 3 3 3 2 EamA-like transporter family DUF1510 PF07423.6 EGO25357.1 - 0.0048 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF3328 PF11807.3 EGO25357.1 - 0.0092 15.6 0.5 2.3 7.8 0.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3328) Neur_chan_memb PF02932.11 EGO25357.1 - 0.044 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 EGO25357.1 - 0.27 9.2 2.0 0.35 8.8 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SieB PF14163.1 EGO25357.1 - 0.74 9.3 6.6 0.43 10.1 0.0 2.8 3 0 0 3 3 3 0 Superinfection exclusion protein B Daxx PF03344.10 EGO25357.1 - 1.2 7.5 10.2 1.7 7.0 7.0 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGO25357.1 - 3 5.6 9.5 4 5.2 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3245 PF11595.3 EGO25357.1 - 4.3 7.5 12.0 0.88 9.8 5.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) DUF1761 PF08570.5 EGO25357.1 - 7.2 6.6 12.8 0.22 11.5 1.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) DUF3560 PF12083.3 EGO25358.1 - 0.34 10.9 2.4 14 5.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3560) DUF262 PF03235.9 EGO25359.1 - 2e-15 57.3 0.1 4.3e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF262 Cation_efflux PF01545.16 EGO25360.1 - 1.6e-49 168.4 4.4 2.7e-49 167.7 3.0 1.4 1 1 0 1 1 1 1 Cation efflux family SelP_N PF04592.9 EGO25360.1 - 0.39 10.0 6.5 0.72 9.1 4.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Fe-ADH PF00465.14 EGO25361.1 - 1.2e-67 228.1 0.0 1.5e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGO25361.1 - 3.6e-17 62.4 0.0 6.7e-17 61.6 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Flavin_Reduct PF01613.13 EGO25363.1 - 6.7e-24 84.4 0.4 1e-23 83.8 0.3 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Pkinase PF00069.20 EGO25365.1 - 1.7e-54 184.6 0.1 2.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25365.1 - 2.1e-17 63.0 0.1 5.4e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGO25365.1 - 1.1e-07 31.8 0.2 0.00017 21.4 0.2 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO25365.1 - 0.0064 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EGO25365.1 - 0.086 11.7 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Cellulase PF00150.13 EGO25367.1 - 7.2e-23 81.1 9.4 9.5e-23 80.7 6.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGO25367.1 - 3.1e-05 24.3 0.0 8.3e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EGO25367.1 - 0.0028 16.5 0.0 0.011 14.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EGO25367.1 - 0.029 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase COG5 PF10392.4 EGO25368.1 - 1.9e-28 99.0 1.8 9.3e-28 96.8 0.5 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EGO25368.1 - 4.4e-06 26.4 1.5 2.8e-05 23.8 0.4 3.0 2 1 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.9 EGO25368.1 - 0.028 14.0 1.1 0.086 12.4 0.8 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EGO25368.1 - 0.043 12.7 1.8 0.091 11.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EGO25368.1 - 0.073 12.9 2.2 1.5 8.6 0.3 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ALS_ss_C PF10369.4 EGO25369.1 - 4.8e-22 77.4 0.1 2.2e-20 72.1 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EGO25369.1 - 2.6e-12 45.9 0.1 4.5e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EGO25369.1 - 1.5e-09 37.4 0.3 6.7e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 ACT domain Pkinase PF00069.20 EGO25370.1 - 1.2e-09 37.7 0.2 2.4e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25370.1 - 0.00053 19.1 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Proteasome PF00227.21 EGO25370.1 - 0.017 14.4 0.1 0.024 13.8 0.1 1.4 1 1 0 1 1 1 0 Proteasome subunit HMG_box PF00505.14 EGO25371.1 - 5.1e-13 49.0 1.5 5.1e-13 49.0 1.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO25371.1 - 0.0049 17.2 0.6 0.0049 17.2 0.4 2.2 1 1 1 2 2 2 1 HMG-box domain adh_short PF00106.20 EGO25373.1 - 8.8e-16 58.2 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO25373.1 - 0.00021 20.9 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGO25373.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.16 EGO25374.1 - 7.4e-52 175.9 0.0 9e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family KH_1 PF00013.24 EGO25375.1 - 5.5e-78 256.5 33.5 7.8e-13 47.8 0.5 13.1 13 0 0 13 13 13 10 KH domain KH_3 PF13014.1 EGO25375.1 - 4.6e-63 208.0 26.5 7.3e-09 35.0 0.0 12.7 12 0 0 12 12 12 10 KH domain KH_2 PF07650.12 EGO25375.1 - 8.6e-11 41.2 22.2 0.03 13.8 0.1 8.5 8 1 0 8 8 8 5 KH domain SLS PF14611.1 EGO25375.1 - 1.1e-06 28.1 26.8 0.62 9.4 0.1 8.7 7 4 4 11 11 11 5 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EGO25375.1 - 0.027 14.1 13.5 1.2 8.8 0.0 6.4 8 0 0 8 8 8 0 KH domain DUF1906 PF08924.6 EGO25375.1 - 0.076 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) RRM_1 PF00076.17 EGO25376.1 - 4.4e-10 39.0 0.0 0.00011 21.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO25376.1 - 8.5e-08 32.0 0.0 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EGO25376.1 - 6.2e-07 28.9 0.1 1.6e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 EGO25376.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 EGO25377.1 - 1.6e-29 102.7 0.1 3.8e-29 101.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EGO25377.1 - 3.7e-07 30.0 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region SLT PF01464.15 EGO25378.1 - 8.9e-09 34.8 0.1 1.3e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 EGO25378.1 - 0.0083 15.6 1.0 0.012 15.0 0.7 1.4 1 1 0 1 1 1 1 Lysozyme-like Cyclin PF08613.6 EGO25381.1 - 1.5e-07 31.9 0.0 4.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGO25381.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Fungal_trans_2 PF11951.3 EGO25383.1 - 4.7e-41 140.6 1.9 1.3e-40 139.2 1.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO25383.1 - 2.4e-07 30.5 8.6 4.9e-07 29.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGO25385.1 - 7.2e-57 192.4 0.0 8.7e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25385.1 - 1.4e-33 116.0 0.0 1.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO25385.1 - 0.00017 20.6 0.0 0.00038 19.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Apis_Csd PF11671.3 EGO25385.1 - 0.09 12.5 0.2 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Mga PF05043.8 EGO25385.1 - 0.099 12.9 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Mga helix-turn-helix domain Acetyltransf_1 PF00583.19 EGO25387.1 - 1.4e-13 50.6 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO25387.1 - 6.6e-07 29.4 0.1 1.6e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO25387.1 - 3.6e-06 26.9 0.0 5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO25387.1 - 4.7e-05 23.2 0.0 6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO25387.1 - 0.00053 19.6 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO25387.1 - 0.00079 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lipid_bd PF12888.2 EGO25387.1 - 0.027 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-binding putative hydrolase Acetyltransf_3 PF13302.1 EGO25387.1 - 0.044 13.9 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Herpes_UL16 PF03044.9 EGO25387.1 - 0.096 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family DNA_ligase_A_M PF01068.16 EGO25388.1 - 1.1e-38 132.6 0.1 9.9e-36 123.0 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO25388.1 - 2.1e-36 125.3 0.0 8.8e-36 123.3 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGO25388.1 - 2.4e-17 63.0 0.0 6.9e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.1 EGO25389.1 - 2.1e-16 60.1 0.1 2.3e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TPR_19 PF14559.1 EGO25390.1 - 0.14 12.5 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YbaB_DNA_bd PF02575.11 EGO25392.1 - 0.078 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family BolA PF01722.13 EGO25396.1 - 2e-28 98.1 0.2 2.4e-28 97.9 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein zf-C2H2 PF00096.21 EGO25397.1 - 5.6e-10 38.9 16.4 5.4e-07 29.5 0.4 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO25397.1 - 1.5e-07 31.3 10.1 4.6e-05 23.4 0.1 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO25397.1 - 5e-07 29.6 5.2 0.00064 19.8 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO25397.1 - 0.00017 21.6 0.5 0.0005 20.1 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGO25397.1 - 0.0013 18.3 1.5 0.16 11.6 0.1 2.9 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-met PF12874.2 EGO25397.1 - 0.0072 16.4 0.6 0.026 14.7 0.4 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-BED PF02892.10 EGO25397.1 - 0.0087 15.8 0.2 0.0087 15.8 0.1 2.6 3 0 0 3 3 3 1 BED zinc finger zf-TRAF PF02176.13 EGO25397.1 - 0.1 13.0 0.2 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.5 EGO25397.1 - 0.14 12.1 1.5 4.8 7.2 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Pkinase PF00069.20 EGO25398.1 - 6.5e-55 186.0 0.0 9.7e-38 129.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25398.1 - 2e-24 86.0 0.0 1.7e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO25398.1 - 3.1e-05 23.0 0.1 0.00041 19.3 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGO25398.1 - 0.017 14.8 0.5 0.017 14.8 0.3 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 EGO25398.1 - 0.042 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EGO25398.1 - 0.063 12.0 0.1 0.098 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Homeobox PF00046.24 EGO25399.1 - 3.3e-16 58.6 3.9 8.5e-16 57.3 2.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGO25399.1 - 0.014 15.0 0.2 0.014 15.0 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain ABC_tran PF00005.22 EGO25400.1 - 1.4e-48 164.6 0.0 1.3e-27 96.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO25400.1 - 2.9e-16 60.2 0.7 0.0054 16.7 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGO25400.1 - 3.6e-12 46.0 0.0 0.00013 21.2 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EGO25400.1 - 1.4e-09 37.4 0.1 3.2e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EGO25400.1 - 3.6e-07 31.0 0.0 0.02 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO25400.1 - 1.6e-06 27.5 1.8 0.041 13.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGO25400.1 - 2.8e-06 27.8 0.0 0.026 14.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EGO25400.1 - 3.2e-06 27.3 0.1 0.014 15.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EGO25400.1 - 4.3e-06 26.4 0.4 0.00072 19.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 EGO25400.1 - 4.4e-06 26.6 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 EGO25400.1 - 8.7e-06 25.6 0.0 0.0075 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT PF02985.17 EGO25400.1 - 1.2e-05 25.0 3.0 8.2 6.8 0.1 5.9 5 0 0 5 5 5 0 HEAT repeat DUF87 PF01935.12 EGO25400.1 - 5.1e-05 23.1 0.2 0.25 11.1 0.0 2.8 3 0 0 3 3 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EGO25400.1 - 6.3e-05 23.3 0.1 0.093 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO25400.1 - 6.9e-05 22.0 0.0 0.04 13.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO25400.1 - 8e-05 22.6 3.9 0.27 11.1 0.1 3.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 EGO25400.1 - 0.00011 22.1 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGO25400.1 - 0.00023 20.0 0.3 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EGO25400.1 - 0.00025 20.7 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGO25400.1 - 0.00027 20.4 0.5 0.7 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 EGO25400.1 - 0.00031 21.0 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGO25400.1 - 0.00093 19.0 0.0 1.3 8.9 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EGO25400.1 - 0.0029 17.4 0.2 8 6.3 0.0 3.3 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.1 EGO25400.1 - 0.004 16.5 0.1 8.8 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain HEAT_EZ PF13513.1 EGO25400.1 - 0.0064 16.9 10.6 1.6 9.3 0.2 5.0 3 2 2 5 5 4 2 HEAT-like repeat AAA_13 PF13166.1 EGO25400.1 - 0.007 14.8 0.0 1.1 7.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO25400.1 - 0.012 15.7 0.0 5.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 EGO25400.1 - 0.013 15.3 0.0 0.2 11.4 0.0 2.6 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.1 EGO25400.1 - 0.013 15.0 0.2 11 5.5 0.0 3.3 4 0 0 4 4 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO25400.1 - 0.019 14.4 0.0 3.9 6.8 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EGO25400.1 - 0.029 13.8 0.1 9.1 5.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 EGO25400.1 - 0.036 13.1 0.0 13 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EGO25400.1 - 0.038 13.4 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 EGO25400.1 - 0.047 13.9 9.7 1.7 8.9 0.3 4.3 2 1 1 3 3 2 0 HEAT repeats cobW PF02492.14 EGO25400.1 - 0.061 12.7 0.1 13 5.1 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EGO25400.1 - 0.062 12.9 0.5 14 5.2 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase Arf PF00025.16 EGO25400.1 - 0.084 12.1 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.15 EGO25400.1 - 0.1 11.2 0.1 0.27 9.8 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.22 EGO25400.1 - 0.12 11.7 0.0 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF3584 PF12128.3 EGO25400.1 - 0.19 9.0 1.6 3 5.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MutS_V PF00488.16 EGO25400.1 - 0.19 11.0 0.3 12 5.1 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_24 PF13479.1 EGO25400.1 - 0.24 10.9 1.0 11 5.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain Glyco_hydro_18 PF00704.23 EGO25402.1 - 1e-90 304.6 3.5 1.2e-90 304.3 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nnf1 PF03980.9 EGO25403.1 - 0.0047 16.8 1.8 0.0047 16.8 1.2 1.7 1 1 0 1 1 1 1 Nnf1 APG6 PF04111.7 EGO25403.1 - 0.086 11.8 7.4 0.093 11.7 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RNA_pol_Rpb2_1 PF04563.10 EGO25403.1 - 0.099 11.5 1.0 0.14 11.0 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit ADIP PF11559.3 EGO25403.1 - 0.1 12.4 11.1 0.14 12.0 7.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EGO25403.1 - 0.12 11.9 8.6 0.059 12.9 4.5 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DIRP PF06584.8 EGO25403.1 - 0.13 12.1 1.9 0.17 11.7 1.3 1.2 1 0 0 1 1 1 0 DIRP AAA_13 PF13166.1 EGO25403.1 - 0.34 9.3 9.9 0.38 9.1 6.9 1.0 1 0 0 1 1 1 0 AAA domain TMCO5 PF14992.1 EGO25403.1 - 0.46 9.5 11.2 0.69 8.9 7.8 1.3 1 1 0 1 1 1 0 TMCO5 family Atg14 PF10186.4 EGO25403.1 - 0.77 8.6 9.4 0.87 8.4 6.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EGO25403.1 - 1.5 8.5 9.6 0.2 11.3 3.2 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EGO25403.1 - 2.8 7.5 10.3 3.8 7.0 7.2 1.2 1 0 0 1 1 1 0 IncA protein SPT6_acidic PF14632.1 EGO25403.1 - 5.5 7.2 10.9 8.2 6.6 7.0 1.7 1 1 0 1 1 1 0 Acidic N-terminal SPT6 HMG14_17 PF01101.13 EGO25404.1 - 0.013 16.1 2.8 0.017 15.8 1.9 1.1 1 0 0 1 1 1 0 HMG14 and HMG17 SIP PF04954.8 EGO25405.1 - 0.14 12.4 0.3 0.27 11.5 0.2 1.4 1 0 0 1 1 1 0 Siderophore-interacting protein BORG_CEP PF14957.1 EGO25405.1 - 0.6 11.0 6.0 0.11 13.3 0.7 2.1 2 0 0 2 2 2 0 Cdc42 effector APG6 PF04111.7 EGO25405.1 - 0.87 8.5 9.4 1.2 8.1 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EGO25405.1 - 1 9.7 6.6 1.8 8.9 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Rootletin PF15035.1 EGO25405.1 - 1 9.2 11.3 1.4 8.8 7.5 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GTP_EFTU PF00009.22 EGO25406.1 - 5.7e-21 74.8 0.0 1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO25406.1 - 4.7e-17 61.9 0.4 1.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO25406.1 - 3.1e-06 27.2 2.7 9.4e-06 25.6 0.6 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGO25406.1 - 0.017 14.7 0.2 0.054 13.1 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 MobB PF03205.9 EGO25406.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EGO25406.1 - 0.13 11.7 0.5 7.3 6.0 0.0 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EGO25406.1 - 0.15 12.3 1.7 4.5 7.5 0.0 3.0 3 1 0 3 3 3 0 ABC transporter Form_Nir_trans PF01226.12 EGO25408.1 - 2.3e-74 249.4 19.0 2.7e-74 249.2 13.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Abhydrolase_3 PF07859.8 EGO25409.1 - 2.2e-24 86.2 0.0 4.4e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO25409.1 - 7.3e-13 47.8 0.0 1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO25409.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EGO25409.1 - 0.44 9.2 1.2 2.3 6.8 0.9 1.8 1 1 0 1 1 1 0 Carboxylesterase family DUF3128 PF11326.3 EGO25410.1 - 1.4e-21 76.4 0.4 2e-21 75.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Jiv90 PF14901.1 EGO25410.1 - 0.079 12.9 0.7 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone MCM PF00493.18 EGO25411.1 - 1.2e-139 464.7 0.2 1.6e-139 464.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EGO25411.1 - 1.2e-23 83.8 21.1 1.2e-23 83.8 14.6 2.7 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EGO25411.1 - 2.1e-16 60.4 0.1 6.8e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO25411.1 - 1.1e-07 31.2 0.0 2.5e-06 26.8 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO25411.1 - 6.9e-06 25.8 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGO25411.1 - 0.0012 18.4 0.1 0.034 13.7 0.0 2.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGO25411.1 - 0.0025 17.2 0.1 0.016 14.6 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 EGO25411.1 - 0.03 14.3 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cellulase PF00150.13 EGO25412.1 - 2.4e-31 108.9 6.0 3.2e-31 108.5 4.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EGO25412.1 - 4e-14 51.9 8.3 1.7e-13 49.9 5.7 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 EGO25412.1 - 5.8e-06 26.6 0.0 1.9e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EGO25412.1 - 0.0011 17.9 0.1 0.0041 16.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EGO25412.1 - 0.04 13.0 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase CAP_N PF01213.14 EGO25412.1 - 0.055 12.7 0.4 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MSP1_C PF07462.6 EGO25412.1 - 2.8 6.2 3.4 4.5 5.5 2.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cellulase PF00150.13 EGO25413.1 - 2.4e-25 89.2 10.4 3e-25 88.9 7.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGO25413.1 - 2.3e-05 24.7 0.0 8.2e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EGO25413.1 - 0.00043 19.2 0.0 0.001 18.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EGO25413.1 - 0.011 14.8 0.1 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase adh_short PF00106.20 EGO25414.1 - 5.2e-24 85.0 0.2 6.7e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO25414.1 - 5.6e-12 45.9 0.0 8.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO25414.1 - 2.6e-09 37.0 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO25414.1 - 1.1e-05 25.0 0.0 3.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO25414.1 - 4.1e-05 23.6 0.1 6.2e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Ferrochelatase PF00762.14 EGO25416.1 - 2e-96 322.6 0.0 2.3e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CPSase_sm_chain PF00988.17 EGO25417.1 - 3.2e-44 149.6 0.0 4.9e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EGO25417.1 - 3.2e-36 124.5 0.0 4.3e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO25417.1 - 4.2e-09 36.1 0.1 3.4e-08 33.1 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EGO25417.1 - 0.0011 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family BSD PF03909.12 EGO25418.1 - 6.8e-12 44.9 0.1 1.8e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 BSD domain Scs3p PF10261.4 EGO25420.1 - 3.6e-38 130.9 11.7 3.4e-36 124.4 8.1 2.8 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1109 PF06532.6 EGO25420.1 - 0.013 14.8 3.3 0.089 12.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) Pro_isomerase PF00160.16 EGO25422.1 - 8.8e-46 155.9 0.4 1.1e-45 155.6 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 EGO25423.1 - 1.3e-36 125.6 0.0 2.4e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGO25423.1 - 5.2e-18 64.3 0.1 1.1e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGO25423.1 - 1.8e-15 56.5 0.0 4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO25423.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HTH_AraC PF00165.18 EGO25424.1 - 0.075 12.8 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family zf-RING_2 PF13639.1 EGO25425.1 - 3e-07 30.1 14.7 4.4e-07 29.6 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 EGO25425.1 - 2e-06 27.2 9.3 3.5e-06 26.4 6.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EGO25425.1 - 4.5e-06 26.2 16.2 7.7e-06 25.4 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO25425.1 - 1.7e-05 24.7 13.7 2.6e-05 24.1 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25425.1 - 0.0002 20.9 13.6 0.00031 20.3 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO25425.1 - 0.00021 20.8 10.1 0.00032 20.3 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO25425.1 - 0.00051 20.0 11.8 0.0017 18.3 8.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGO25425.1 - 0.0055 16.4 3.9 0.0097 15.6 2.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGO25425.1 - 0.011 15.5 11.6 0.02 14.7 8.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGO25425.1 - 0.1 12.4 7.5 0.29 11.0 5.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGO25425.1 - 0.55 10.0 12.6 1.4 8.6 8.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger U-box PF04564.10 EGO25425.1 - 1.1 9.2 3.7 0.58 10.1 0.3 2.0 1 1 1 2 2 2 0 U-box domain Homeobox PF00046.24 EGO25427.1 - 4.4e-18 64.6 2.1 7.4e-18 63.9 1.5 1.4 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 EGO25428.1 - 3.4e-37 128.0 0.0 4.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25428.1 - 1.4e-22 79.9 0.0 5e-22 78.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO25428.1 - 0.0066 15.4 0.0 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO25428.1 - 0.062 13.0 3.9 0.91 9.2 0.0 2.9 3 1 0 4 4 4 0 Phosphotransferase enzyme family DUF1466 PF07326.6 EGO25429.1 - 0.094 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) ALAD PF00490.16 EGO25430.1 - 1e-118 395.9 0.0 1.2e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-RING_2 PF13639.1 EGO25431.1 - 3.6e-10 39.5 1.5 7.7e-10 38.4 1.0 1.6 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO25431.1 - 5.1e-09 36.1 1.5 8e-09 35.4 1.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger Ank_2 PF12796.2 EGO25431.1 - 5.1e-09 36.3 0.0 7.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO25431.1 - 1.6e-08 34.5 0.1 3.3e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO25431.1 - 1.7e-08 34.7 0.1 0.00069 20.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO25431.1 - 7.7e-08 31.7 0.2 4.3e-07 29.4 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat zf-Apc11 PF12861.2 EGO25431.1 - 5.6e-07 29.3 2.3 1.7e-05 24.5 2.8 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ank_3 PF13606.1 EGO25431.1 - 2.3e-05 24.1 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat zf-C3HC4_2 PF13923.1 EGO25431.1 - 0.00025 20.9 1.2 0.00025 20.9 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO25431.1 - 0.00027 20.5 1.7 0.0016 18.0 1.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25431.1 - 0.0092 15.6 1.4 0.058 13.1 1.0 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO25431.1 - 0.036 13.9 3.7 0.083 12.7 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EGO25431.1 - 0.045 13.7 4.2 0.13 12.3 2.9 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 EGO25431.1 - 0.049 13.3 3.9 0.31 10.7 2.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rpr2 PF04032.11 EGO25432.1 - 1.8e-20 72.5 0.1 3.9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF164 PF02591.10 EGO25432.1 - 0.0051 16.6 0.4 0.014 15.1 0.3 1.7 1 0 0 1 1 1 1 Putative zinc ribbon domain DPBB_1 PF03330.13 EGO25433.1 - 7.6e-05 22.6 0.4 0.00031 20.6 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Bromodomain PF00439.20 EGO25435.1 - 4.1e-25 87.5 0.1 9.1e-25 86.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGO25435.1 - 5.1e-07 29.7 0.4 1e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO25435.1 - 0.00016 21.6 0.2 0.00034 20.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family 2-Hacid_dh_C PF02826.14 EGO25436.1 - 2.2e-47 160.5 0.0 4.3e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO25436.1 - 2.2e-18 65.9 0.0 2.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO25436.1 - 1.1e-05 25.3 0.0 4.3e-05 23.4 0.0 1.9 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EGO25436.1 - 0.031 14.5 0.0 0.16 12.2 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 EGO25436.1 - 0.084 13.3 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EGO25436.1 - 0.1 13.0 0.0 0.64 10.4 0.0 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGO25436.1 - 0.11 12.6 0.0 0.66 10.0 0.0 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_U35_2 PF14550.1 EGO25436.1 - 0.13 11.8 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Putative phage protease XkdF EXS PF03124.9 EGO25437.1 - 2.4e-87 293.1 1.1 2.8e-87 292.9 0.8 1.0 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.8 EGO25437.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-C2H2_jaz PF12171.3 EGO25438.1 - 3.9e-06 26.8 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 EGO25438.1 - 0.00021 21.0 6.6 0.00021 21.0 4.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 EGO25438.1 - 0.00053 20.0 0.1 0.00086 19.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EGO25438.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger Atg14 PF10186.4 EGO25438.1 - 8.1 5.2 11.8 7.2 5.4 1.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 tRNA-synt_1 PF00133.17 EGO25439.1 - 1.4e-215 716.9 0.0 3.2e-215 715.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGO25439.1 - 4e-27 94.8 0.1 8.8e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGO25439.1 - 9.6e-18 63.9 0.2 1.1e-06 27.6 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EGO25439.1 - 0.13 11.3 0.0 0.61 9.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pput2613-deam PF14427.1 EGO25439.1 - 0.22 11.2 0.0 0.49 10.0 0.0 1.5 1 0 0 1 1 1 0 Pput_2613-like deaminase PC4 PF02229.11 EGO25440.1 - 2.2e-20 71.6 0.2 5.1e-20 70.4 0.2 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ABC1 PF03109.11 EGO25441.1 - 9.8e-31 106.1 0.0 2e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EGO25441.1 - 0.0013 18.1 0.1 0.0056 16.0 0.0 1.9 2 0 0 2 2 2 1 RIO1 family DUF605 PF04652.11 EGO25444.1 - 1.4 8.2 16.2 2.3 7.5 11.2 1.3 1 0 0 1 1 1 0 Vta1 like Tymo_coat PF00983.13 EGO25446.1 - 0.086 12.5 0.9 0.098 12.3 0.6 1.1 1 0 0 1 1 1 0 Tymovirus coat protein zf-CCCH PF00642.19 EGO25447.1 - 8.1e-14 50.9 15.6 4.4e-07 29.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EGO25447.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO25447.1 - 0.026 14.1 0.0 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg14 PF08660.6 EGO25448.1 - 6.2e-49 166.2 0.0 8.6e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.23 EGO25449.1 - 1.3e-28 97.3 5.6 2.6e-05 23.6 1.3 7.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGO25449.1 - 8.1e-27 92.6 9.5 2.6e-10 39.8 1.4 6.3 6 1 1 7 7 7 4 TPR repeat APC8 PF04049.8 EGO25449.1 - 2e-23 82.7 0.0 5e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 EGO25449.1 - 2.1e-22 77.2 16.6 0.0036 17.0 0.1 8.3 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25449.1 - 3.4e-22 76.4 4.3 0.0027 17.3 0.0 8.3 6 1 2 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25449.1 - 1.9e-16 59.7 15.4 8.2e-08 32.0 0.0 6.2 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25449.1 - 5.4e-16 57.6 10.8 0.014 15.9 0.1 8.2 5 1 4 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGO25449.1 - 8.2e-16 58.2 18.6 3.8e-06 27.4 1.5 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGO25449.1 - 1.7e-11 43.0 10.8 0.014 15.1 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25449.1 - 4.2e-10 39.0 1.5 0.092 12.9 0.2 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO25449.1 - 1e-09 38.5 6.0 0.0053 17.0 0.0 6.3 5 1 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO25449.1 - 8e-07 29.1 11.8 0.058 13.5 3.7 5.3 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGO25449.1 - 1e-06 28.4 9.9 0.0002 21.1 1.2 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO25449.1 - 8e-06 25.9 12.5 4.1 8.0 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ChAPs PF09295.5 EGO25449.1 - 0.00082 18.2 0.0 0.45 9.2 0.0 3.2 2 2 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EGO25449.1 - 0.0016 18.2 3.1 2.7 8.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EGO25449.1 - 0.007 15.7 5.0 0.65 9.3 0.1 3.8 4 1 1 5 5 5 1 26S proteasome subunit RPN7 MIT PF04212.13 EGO25449.1 - 0.056 13.3 2.2 0.4 10.5 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EGO25449.1 - 0.76 9.6 4.8 4.8 6.9 0.1 3.7 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) FAT PF02259.18 EGO25449.1 - 1.1 8.2 8.8 2.7 6.9 0.1 3.8 2 1 1 4 4 4 0 FAT domain GLTSCR1 PF15249.1 EGO25450.1 - 5.5e-22 77.9 0.1 9.2e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region Mito_carr PF00153.22 EGO25451.1 - 7.5e-17 60.8 0.0 2.1e-09 36.9 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein SNF2_N PF00176.18 EGO25453.1 - 1.1e-61 208.2 0.1 1.6e-61 207.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO25453.1 - 1e-14 54.1 0.0 3.6e-14 52.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO25453.1 - 1.7e-05 24.7 0.0 5.9e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_3 PF12836.2 EGO25453.1 - 0.0013 18.6 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif TRI12 PF06609.8 EGO25454.1 - 3e-09 35.6 13.5 4.3e-09 35.1 9.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EGO25454.1 - 2e-06 26.8 30.3 0.0002 20.1 15.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Ank_2 PF12796.2 EGO25456.1 - 2.9e-10 40.3 0.0 7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO25456.1 - 5.7e-10 39.4 0.1 1.4e-06 28.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO25456.1 - 5.5e-08 32.2 0.0 1.4e-05 24.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGO25456.1 - 9.6e-06 25.6 0.1 3.2e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO25456.1 - 0.0014 18.6 0.1 0.2 11.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_31 PF13847.1 EGO25456.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_61 PF03443.9 EGO25457.1 - 5.6e-62 209.4 0.3 6.3e-62 209.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.7 EGO25458.1 - 4.4e-39 133.2 23.5 8.3e-39 132.3 16.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Ribosomal_S8e PF01201.17 EGO25459.1 - 4.6e-40 136.8 5.6 9.8e-40 135.7 3.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 EGO25459.1 - 0.062 13.2 0.8 0.081 12.8 0.1 1.4 2 0 0 2 2 2 0 Mer2 DUF3959 PF13105.1 EGO25459.1 - 6.9 5.9 6.0 0.62 9.3 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) Yip1 PF04893.12 EGO25460.1 - 9.6e-05 21.9 1.5 0.00013 21.5 1.0 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1746 PF08508.5 EGO25462.1 - 7.1e-06 25.9 3.8 1.8e-05 24.6 2.6 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) PIG-P PF08510.7 EGO25462.1 - 0.041 13.5 0.4 0.063 12.9 0.3 1.4 1 0 0 1 1 1 0 PIG-P DUF4131 PF13567.1 EGO25462.1 - 6.6 6.1 8.1 0.16 11.3 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspannin PF00335.15 EGO25463.1 - 6.1e-07 28.9 12.0 3.1e-06 26.6 8.3 1.9 1 1 0 1 1 1 1 Tetraspanin family DUF2970 PF11174.3 EGO25463.1 - 0.059 12.9 0.1 0.059 12.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) DUF3671 PF12420.3 EGO25463.1 - 0.58 10.1 4.0 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF4118 PF13493.1 EGO25463.1 - 4.6 7.4 15.3 0.085 13.0 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4118) Hist_deacetyl PF00850.14 EGO25464.1 - 2e-85 286.8 0.2 3.7e-85 285.9 0.2 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EGO25464.1 - 1.2e-26 93.2 0.1 1.8e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain Amidohydro_4 PF13147.1 EGO25465.1 - 3.3e-20 73.2 2.7 1.2e-19 71.4 1.9 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EGO25465.1 - 5.9e-11 42.0 0.0 2.4e-08 33.6 0.0 3.2 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO25465.1 - 1.3e-08 34.8 0.4 6.8e-06 25.9 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EGO25465.1 - 3e-08 33.3 0.4 2.7e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Rad10 PF03834.9 EGO25466.1 - 2.1e-27 94.5 0.1 4.5e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGO25466.1 - 4.1e-07 30.0 0.0 7.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGO25466.1 - 0.0046 16.8 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 EGO25466.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif Amidohydro_4 PF13147.1 EGO25467.1 - 2.8e-14 53.8 9.0 2.9e-10 40.6 0.1 3.2 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EGO25467.1 - 6.3e-12 45.1 0.3 6.3e-09 35.5 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO25467.1 - 4.6e-08 33.0 0.1 0.00016 21.4 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 EGO25467.1 - 0.012 14.8 0.6 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Amidohydrolase family TRP PF06011.7 EGO25468.1 - 3.2e-76 256.6 24.8 4.5e-76 256.1 17.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO25468.1 - 7.4e-27 94.1 0.0 1.2e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 ML-like domain OPT PF03169.10 EGO25469.1 - 2.7e-165 551.3 49.1 3e-165 551.1 34.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 EGO25469.1 - 0.055 13.2 3.4 0.25 11.1 2.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) MgsA_C PF12002.3 EGO25470.1 - 8.6e-56 188.2 0.1 1.3e-55 187.6 0.1 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EGO25470.1 - 2.5e-16 60.0 0.0 8.8e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO25470.1 - 2.1e-13 49.8 0.0 3.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGO25470.1 - 3.5e-09 36.4 0.0 1.5e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO25470.1 - 8.9e-07 28.2 0.0 0.032 13.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EGO25470.1 - 5.2e-06 26.6 0.1 0.00031 20.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGO25470.1 - 1.7e-05 24.8 0.1 0.0058 16.6 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EGO25470.1 - 3.7e-05 23.3 0.0 0.0093 15.4 0.0 3.3 1 1 0 1 1 1 1 AAA-like domain Sigma54_activat PF00158.21 EGO25470.1 - 4.1e-05 23.1 0.0 0.0041 16.6 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EGO25470.1 - 4.2e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO25470.1 - 0.00017 22.4 0.0 0.00048 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO25470.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EGO25470.1 - 0.00077 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 EGO25470.1 - 0.0037 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO25470.1 - 0.0042 16.9 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGO25470.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EGO25470.1 - 0.0044 17.1 0.0 0.0086 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EGO25470.1 - 0.0054 17.0 0.0 0.034 14.4 0.0 2.0 2 1 0 2 2 1 1 ABC transporter AAA_3 PF07726.6 EGO25470.1 - 0.0063 16.1 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGO25470.1 - 0.013 15.2 0.1 0.16 11.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Rad17 PF03215.10 EGO25470.1 - 0.016 13.9 0.2 0.77 8.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 EGO25470.1 - 0.031 13.9 0.0 1.4 8.5 0.0 2.5 1 1 1 2 2 2 0 DNA polymerase III, delta subunit Viral_helicase1 PF01443.13 EGO25470.1 - 0.035 13.6 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EGO25470.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 EGO25470.1 - 0.061 11.7 0.0 0.088 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EGO25470.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_19 PF13245.1 EGO25470.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 EGO25470.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTP_transferase PF00483.18 EGO25471.1 - 6.4e-09 35.4 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGO25471.1 - 1.1e-06 28.7 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EGO25471.1 - 3e-05 23.3 3.4 0.033 13.6 0.1 3.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO25471.1 - 0.23 11.0 6.3 4.6 6.8 1.8 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Nucleoplasmin PF03066.10 EGO25471.1 - 1.6 8.2 16.2 3.6 7.1 11.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin eIF-3c_N PF05470.7 EGO25472.1 - 1.9e-183 610.7 23.1 1.9e-183 610.7 16.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EGO25472.1 - 5.1e-14 52.4 1.3 1.7e-13 50.8 0.0 2.6 3 0 0 3 3 3 1 PCI domain ARD PF03079.9 EGO25473.1 - 9.6e-45 152.3 0.3 1.1e-44 152.1 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGO25473.1 - 2.9e-09 36.3 0.2 6e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGO25473.1 - 5.3e-07 29.4 0.1 7.6e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGO25473.1 - 0.00063 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EGO25473.1 - 0.018 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) OSCP PF00213.13 EGO25475.1 - 9.5e-40 136.2 0.6 1.1e-39 136.0 0.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Peptidase_C15 PF01470.12 EGO25476.1 - 8.1e-11 42.1 0.0 0.00045 20.1 0.0 2.4 2 0 0 2 2 2 2 Pyroglutamyl peptidase APS_kinase PF01583.15 EGO25477.1 - 6.6e-71 237.0 0.0 7.7e-71 236.8 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGO25477.1 - 1.8e-07 31.1 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO25477.1 - 1.8e-05 25.5 0.1 3.5e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO25477.1 - 0.00017 21.9 0.2 0.00047 20.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO25477.1 - 0.0066 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 EGO25477.1 - 0.02 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EGO25477.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HisKA_3 PF07730.8 EGO25477.1 - 0.098 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase Pkinase PF00069.20 EGO25480.1 - 4e-66 222.8 0.0 4.8e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25480.1 - 1.9e-48 164.8 0.0 2.4e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO25480.1 - 1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO25480.1 - 6.5e-05 22.7 0.0 0.16 11.6 0.0 2.5 2 1 0 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EGO25480.1 - 0.0056 16.0 0.1 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family REV PF00424.13 EGO25480.1 - 0.036 13.9 1.8 0.083 12.7 0.6 2.0 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Asp-B-Hydro_N PF05279.6 EGO25481.1 - 8.3 6.1 30.5 16 5.2 21.2 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BAR PF03114.13 EGO25483.1 - 1.1e-48 165.7 0.8 1.3e-48 165.5 0.6 1.0 1 0 0 1 1 1 1 BAR domain SYF2 PF08231.7 EGO25483.1 - 0.12 12.4 3.2 0.37 10.9 2.2 1.9 1 1 0 1 1 1 0 SYF2 splicing factor DUF3987 PF13148.1 EGO25485.1 - 0.0061 15.1 5.7 0.0065 15.0 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) Med19 PF10278.4 EGO25485.1 - 0.11 12.2 6.2 0.12 12.0 4.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DNA_pol3_a_NII PF11490.3 EGO25485.1 - 2.8 7.5 10.4 3.7 7.1 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RR_TM4-6 PF06459.7 EGO25485.1 - 3.5 7.4 8.3 3.8 7.3 5.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RHD3 PF05879.7 EGO25487.1 - 2.7e-245 815.8 0.7 1.6e-244 813.2 0.5 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EGO25487.1 - 8.4e-07 28.2 0.2 1.8e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EGO25487.1 - 3.2e-05 23.8 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EGO25487.1 - 7.8e-05 22.6 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO25487.1 - 0.00011 22.7 0.0 0.00034 21.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EGO25487.1 - 0.0023 17.9 0.0 0.0066 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain S-antigen PF05756.6 EGO25488.1 - 0.048 13.6 0.1 0.052 13.5 0.1 1.0 1 0 0 1 1 1 0 S-antigen protein SAA PF00277.13 EGO25488.1 - 0.057 13.7 0.7 0.069 13.5 0.5 1.1 1 0 0 1 1 1 0 Serum amyloid A protein DUF4637 PF15470.1 EGO25488.1 - 0.08 12.5 0.2 0.087 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Btz PF09405.5 EGO25488.1 - 0.89 9.5 4.5 1.1 9.3 3.1 1.1 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding AMP-binding PF00501.23 EGO25489.1 - 4.3e-45 153.8 0.0 6.3e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO25489.1 - 0.029 15.3 0.0 0.077 13.9 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glutaredoxin PF00462.19 EGO25492.1 - 5.6e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Glyco_hydro_35 PF01301.14 EGO25493.1 - 1.2e-64 218.6 1.7 3e-64 217.3 0.3 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EGO25493.1 - 2.3e-50 169.5 12.0 7.4e-27 93.8 2.8 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EGO25493.1 - 6.6e-49 165.7 7.8 9.5e-49 165.2 4.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EGO25493.1 - 3.6e-19 67.9 0.3 1.1e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EGO25493.1 - 0.0075 15.4 0.1 0.039 13.1 0.0 2.1 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CMAS PF02353.15 EGO25496.1 - 1e-31 110.0 0.3 1.5e-31 109.5 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EGO25496.1 - 9.3e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO25496.1 - 2e-11 44.4 0.0 3.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO25496.1 - 1.6e-10 40.7 0.0 2.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO25496.1 - 4.8e-09 36.1 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO25496.1 - 6.8e-09 36.1 0.0 2.2e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGO25496.1 - 1.1e-07 31.3 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGO25496.1 - 2.3e-06 26.8 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGO25496.1 - 2.6e-06 27.7 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGO25496.1 - 5.4e-05 22.4 0.0 8.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.6 EGO25496.1 - 7.6e-05 21.5 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase NodS PF05401.6 EGO25496.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EGO25496.1 - 0.0029 17.6 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGO25496.1 - 0.017 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.7 EGO25496.1 - 0.031 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MetW PF07021.7 EGO25496.1 - 0.037 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MDM31_MDM32 PF08118.6 EGO25497.1 - 2e-151 504.9 0.7 2.3e-151 504.6 0.5 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Sugar_tr PF00083.19 EGO25498.1 - 6.6e-109 364.4 11.2 1.1e-108 363.6 7.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO25498.1 - 2.6e-18 65.8 43.9 2e-13 49.7 9.3 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO25498.1 - 0.0018 16.5 3.1 0.0018 16.5 2.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Bax1-I PF01027.15 EGO25500.1 - 4.5e-41 140.7 24.8 5.6e-41 140.4 17.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 YbaJ PF10757.4 EGO25501.1 - 0.59 10.2 2.5 1.1 9.4 0.0 2.7 4 0 0 4 4 4 0 Biofilm formation regulator YbaJ HR1 PF02185.11 EGO25502.1 - 0.064 13.0 4.0 0.11 12.2 2.8 1.3 1 0 0 1 1 1 0 Hr1 repeat Uds1 PF15456.1 EGO25502.1 - 0.096 12.6 4.8 0.15 12.0 3.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation AAA_23 PF13476.1 EGO25502.1 - 0.33 11.2 6.7 0.45 10.8 4.6 1.2 1 0 0 1 1 1 0 AAA domain SPT6_acidic PF14632.1 EGO25502.1 - 5.5 7.2 13.2 7.5 6.7 9.2 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Glyco_hydro_92 PF07971.7 EGO25503.1 - 1.6e-120 403.1 3.2 2e-120 402.8 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Pept_tRNA_hydro PF01195.14 EGO25504.1 - 1.1e-35 122.7 0.0 1.3e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase HlyIII PF03006.15 EGO25505.1 - 1e-39 136.2 18.8 1.4e-39 135.8 13.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related TFIID_20kDa PF03847.8 EGO25506.1 - 1.8e-27 95.3 0.1 3e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EGO25506.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hyaluronidase_1 PF07212.6 EGO25506.1 - 0.035 13.1 0.1 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Hyaluronidase protein (HylP) AFG1_ATPase PF03969.11 EGO25507.1 - 4.8e-58 196.6 0.0 2.7e-52 177.8 0.0 3.6 2 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.1 EGO25507.1 - 1.4e-05 25.1 0.0 4.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO25507.1 - 0.00029 20.9 0.0 0.00095 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO25507.1 - 0.0027 17.1 0.4 0.009 15.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EGO25507.1 - 0.022 14.1 0.0 2.1 7.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO25507.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EGO25507.1 - 0.069 13.1 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-CCHC PF00098.18 EGO25511.1 - 3e-09 36.3 0.9 4.4e-09 35.8 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO25511.1 - 0.0092 15.6 0.3 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO25511.1 - 0.028 14.1 1.3 0.049 13.3 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO25511.1 - 0.041 13.5 0.2 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Acetyltransf_1 PF00583.19 EGO25513.1 - 2.7e-06 27.3 0.0 1.3e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO25513.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO25513.1 - 0.026 14.2 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 EGO25513.1 - 0.081 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EGO25516.1 - 2.7e-24 85.7 0.0 4.5e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25516.1 - 1.2e-14 54.0 0.0 1.2e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO25516.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EGO25516.1 - 0.021 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGO25516.1 - 0.091 12.3 0.1 8 5.9 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase Asn_synthase PF00733.16 EGO25517.1 - 2.3e-49 168.1 0.0 3.3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGO25517.1 - 7.3e-07 28.9 0.0 2.1e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.8 EGO25517.1 - 0.00052 19.3 0.0 0.0017 17.7 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC GATase_6 PF13522.1 EGO25517.1 - 0.024 14.5 0.0 0.078 12.9 0.0 1.9 1 1 0 1 1 1 0 Glutamine amidotransferase domain DnaJ PF00226.26 EGO25518.1 - 5.5e-11 42.0 0.1 9.7e-11 41.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1771 PF08590.5 EGO25519.1 - 5.1e-22 77.6 3.2 5.1e-22 77.6 2.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGO25519.1 - 1.6e-14 53.8 0.4 3.5e-14 52.7 0.3 1.6 1 0 0 1 1 1 1 Smr domain DUF3287 PF11690.3 EGO25519.1 - 0.048 13.7 2.5 0.09 12.8 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF1771 PF08590.5 EGO25521.1 - 7.4e-22 77.1 3.7 7.4e-22 77.1 2.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGO25521.1 - 1.7e-14 53.7 0.1 3.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Smr domain DUF3287 PF11690.3 EGO25521.1 - 0.052 13.6 0.6 0.12 12.4 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) ODC_AZ PF02100.12 EGO25522.1 - 4.8e-19 67.8 0.0 6.8e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.15 EGO25523.1 - 5.7e-28 96.4 1.3 5.7e-28 96.4 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGO25523.1 - 6.5e-22 76.5 0.0 1.1e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.17 EGO25525.1 - 1.8e-61 208.0 0.0 6.9e-61 206.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 EGO25526.1 - 1.6e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO25526.1 - 1.9e-07 30.5 0.0 2.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF3320 PF11784.3 EGO25526.1 - 0.0082 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3320) HEM4 PF02602.10 EGO25526.1 - 0.015 14.5 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD AAA_2 PF07724.9 EGO25527.1 - 3.6e-50 170.2 0.0 4.4e-46 156.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGO25527.1 - 6.8e-25 87.7 0.0 3.9e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGO25527.1 - 6.6e-24 83.6 0.4 2.9e-23 81.5 0.3 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EGO25527.1 - 3.2e-16 58.9 11.5 1.1e-11 44.5 0.6 4.2 4 0 0 4 4 4 2 Clp amino terminal domain AAA_5 PF07728.9 EGO25527.1 - 1e-15 57.6 0.0 2.2e-08 33.9 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO25527.1 - 1.6e-11 44.4 0.0 0.00053 20.1 0.0 3.7 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EGO25527.1 - 1.8e-11 44.3 4.8 0.00012 22.0 0.0 4.7 3 3 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 EGO25527.1 - 3.9e-08 32.9 0.0 4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EGO25527.1 - 1.7e-07 30.8 0.0 0.00055 19.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGO25527.1 - 3.3e-06 27.4 2.3 0.005 17.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGO25527.1 - 7.9e-06 24.8 1.9 0.28 9.8 0.0 4.0 3 1 1 4 4 4 2 TIP49 C-terminus Mg_chelatase PF01078.16 EGO25527.1 - 1.5e-05 24.3 0.5 0.013 14.6 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGO25527.1 - 1.7e-05 24.0 0.2 0.0084 15.2 0.0 3.2 4 0 0 4 4 4 1 Zeta toxin AAA_24 PF13479.1 EGO25527.1 - 3.3e-05 23.5 0.0 0.051 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGO25527.1 - 5.3e-05 24.0 9.5 0.044 14.6 2.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO25527.1 - 5.9e-05 22.7 0.0 0.32 10.7 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain Arch_ATPase PF01637.13 EGO25527.1 - 0.00011 22.0 0.2 0.83 9.3 0.0 4.3 3 1 1 4 4 4 1 Archaeal ATPase AAA_33 PF13671.1 EGO25527.1 - 0.00021 21.1 0.0 0.18 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO25527.1 - 0.00022 21.3 0.2 1.3 9.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.7 EGO25527.1 - 0.00063 19.4 0.0 0.24 11.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 EGO25527.1 - 0.0016 18.8 2.6 8.6 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 EGO25527.1 - 0.0016 17.5 0.1 2.4 7.1 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EGO25527.1 - 0.0024 17.8 0.8 1.2 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EGO25527.1 - 0.0079 16.4 0.3 2.7 8.2 0.0 3.3 3 0 0 3 3 3 1 ABC transporter PhoH PF02562.11 EGO25527.1 - 0.01 15.0 0.0 0.78 8.9 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 EGO25527.1 - 0.023 14.2 0.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO25527.1 - 0.027 13.8 0.6 7.5 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EGO25527.1 - 0.032 13.9 0.0 3.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EGO25527.1 - 0.036 13.2 0.0 2.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 EGO25527.1 - 0.053 13.0 3.9 2.6 7.5 0.9 3.4 3 1 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EGO25527.1 - 0.061 12.9 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Torsin PF06309.6 EGO25527.1 - 0.061 13.1 0.0 1 9.2 0.0 2.5 3 0 0 3 3 2 0 Torsin AAA_3 PF07726.6 EGO25527.1 - 0.066 12.8 0.0 32 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EGO25527.1 - 0.11 12.3 0.0 4.7 7.0 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EGO25527.1 - 0.27 10.6 2.6 3 7.1 0.0 3.2 3 1 1 4 4 3 0 AAA-like domain zf-Tim10_DDP PF02953.10 EGO25528.1 - 7.6e-20 69.9 0.5 9.5e-20 69.6 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Myotub-related PF06602.9 EGO25528.1 - 0.02 13.7 0.0 0.021 13.6 0.0 1.0 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Nucleos_tra2_C PF07662.8 EGO25529.1 - 7.3e-66 221.6 1.3 7.3e-66 221.6 0.9 2.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EGO25529.1 - 3.9e-18 65.5 4.5 3.9e-18 65.5 3.1 4.1 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EGO25529.1 - 0.0029 17.5 5.9 0.0029 17.5 4.1 3.0 2 0 0 2 2 2 1 Nucleoside recognition WD40 PF00400.27 EGO25530.1 - 1.7e-19 68.8 6.5 2.1e-06 27.3 0.0 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Cu-oxidase_2 PF07731.9 EGO25530.1 - 0.025 14.0 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Multicopper oxidase RPA_interact_C PF14768.1 EGO25531.1 - 0.018 15.4 0.1 0.029 14.7 0.1 1.4 1 0 0 1 1 1 0 Replication protein A interacting C-terminal ABC2_membrane_3 PF12698.2 EGO25532.1 - 2 7.3 6.3 2.6 7.0 4.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MPC PF03650.8 EGO25533.1 - 5.1e-38 129.6 0.4 6e-38 129.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Palm_thioest PF02089.10 EGO25535.1 - 4.2e-57 193.2 0.0 8e-50 169.3 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EGO25535.1 - 0.0024 17.4 0.0 0.0063 16.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EGO25535.1 - 0.13 11.3 0.0 0.38 9.8 0.0 1.8 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF563 PF04577.9 EGO25536.1 - 4e-19 69.3 1.5 2.2e-18 66.9 0.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF563) DUF3421 PF11901.3 EGO25537.1 - 3.3e-23 81.6 1.9 3e-11 43.1 0.1 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 EGO25537.1 - 0.38 10.3 5.1 0.18 11.4 0.6 2.8 2 0 0 2 2 2 0 Carbohydrate binding domain PAT1 PF09770.4 EGO25537.1 - 1 7.5 5.0 1.2 7.3 3.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cation_efflux PF01545.16 EGO25538.1 - 0.019 14.0 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 Cation efflux family P12 PF12669.2 EGO25538.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.4 3 0 0 3 3 3 0 Virus attachment protein p12 family DUF3586 PF12131.3 EGO25539.1 - 0.0016 18.4 0.2 0.0026 17.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) CsbD PF05532.7 EGO25541.1 - 6.8e-16 57.6 14.1 4.7e-09 35.7 1.1 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 EGO25541.1 - 0.026 14.5 0.9 0.052 13.6 0.2 2.0 1 1 1 2 2 2 0 Heat shock protein 9/12 M11L PF11099.3 EGO25545.1 - 1.7 8.3 5.1 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Apoptosis regulator M11L like Cut8_N PF14482.1 EGO25547.1 - 0.018 15.0 0.2 0.046 13.7 0.1 1.8 1 0 0 1 1 1 0 Cut8 proteasome-binding domain FAD_binding_3 PF01494.14 EGO25549.1 - 7.8e-30 104.1 0.0 1.2e-29 103.4 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO25549.1 - 1.3e-09 37.4 1.4 0.0002 20.3 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO25549.1 - 1.4e-05 25.3 0.7 0.033 14.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO25549.1 - 0.00026 20.9 1.2 0.0023 17.8 0.8 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO25549.1 - 0.00093 17.9 0.3 1.2 7.6 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EGO25549.1 - 0.0035 17.3 0.0 0.0086 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EGO25549.1 - 0.0066 15.3 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.19 EGO25549.1 - 0.052 12.3 0.3 0.21 10.4 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EGO25549.1 - 0.053 12.4 0.0 2.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Ribosomal_L11_N PF03946.9 EGO25550.1 - 3.8e-18 64.6 0.1 6.4e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGO25550.1 - 9.8e-13 48.0 0.3 1.7e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pab87_oct PF13969.1 EGO25550.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Pab87 octamerisation domain Cyclin PF08613.6 EGO25551.1 - 2.1e-28 99.6 0.2 3.5e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGO25551.1 - 0.0001 21.8 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain E1-E2_ATPase PF00122.15 EGO25552.1 - 4.6e-62 209.0 0.9 4.6e-62 209.0 0.6 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGO25552.1 - 1.1e-21 78.2 0.1 2.5e-21 77.0 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO25552.1 - 2.4e-11 44.1 0.0 4.9e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO25552.1 - 9.7e-11 40.9 0.0 2.3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO25552.1 - 0.0095 15.5 0.1 0.0095 15.5 0.1 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase TRI5 PF06330.6 EGO25553.1 - 7.1e-06 24.9 0.0 0.035 12.7 0.0 2.1 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) MFS_1 PF07690.11 EGO25560.1 - 2.4e-17 62.6 35.8 2.4e-17 62.6 24.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FBPase_3 PF01950.11 EGO25560.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase SF3a60_bindingd PF12108.3 EGO25561.1 - 0.028 13.9 0.2 0.062 12.8 0.2 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF1560 PF07597.6 EGO25561.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) WD40 PF00400.27 EGO25562.1 - 3.9e-62 204.0 25.3 7.5e-12 44.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO25562.1 - 5.3e-06 24.8 3.9 0.015 13.4 0.3 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 EGO25562.1 - 0.0006 18.8 0.0 0.094 11.5 0.0 2.7 2 2 1 3 3 3 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EGO25562.1 - 0.0052 15.1 0.0 0.51 8.5 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGO25562.1 - 0.0055 16.4 0.4 0.14 11.8 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGO25562.1 - 0.026 14.2 1.6 15 5.3 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1416 PF07210.7 EGO25562.1 - 0.074 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) IU_nuc_hydro PF01156.14 EGO25563.1 - 6.1e-35 120.9 0.0 8e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Phage_lysis PF03245.8 EGO25566.1 - 0.068 13.1 1.3 0.096 12.6 0.9 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Pox_A_type_inc PF04508.7 EGO25566.1 - 0.4 10.5 4.4 9.6 6.2 0.4 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat gag-asp_proteas PF13975.1 EGO25567.1 - 2.7e-06 27.1 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO25567.1 - 4.9e-05 23.7 0.1 0.0023 18.4 0.0 2.7 2 1 1 3 3 3 1 Aspartyl protease RVP_2 PF08284.6 EGO25567.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease UBN2_2 PF14227.1 EGO25568.1 - 3.2e-09 36.3 1.5 5.1e-09 35.7 1.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO25568.1 - 1.4e-05 24.8 0.1 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Vfa1 PF08432.5 EGO25568.1 - 0.048 13.6 4.9 0.064 13.2 3.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BLVR PF06375.6 EGO25568.1 - 2.7 7.8 9.6 3.8 7.3 6.6 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Arginase PF00491.16 EGO25570.1 - 6e-85 284.9 0.1 7.4e-85 284.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGO25570.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SBF PF01758.11 EGO25571.1 - 1.1e-05 24.8 3.5 1.4e-05 24.5 2.4 1.2 1 0 0 1 1 1 1 Sodium Bile acid symporter family YbgT_YccB PF08173.6 EGO25571.1 - 4.8 7.0 6.9 2.9 7.7 1.6 2.4 2 0 0 2 2 2 0 Membrane bound YbgT-like protein RabGAP-TBC PF00566.13 EGO25572.1 - 3.2e-40 137.9 0.0 4.2e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_N PF01602.15 EGO25573.1 - 1.5e-19 69.7 1.3 3.5e-19 68.5 0.6 1.8 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 EGO25573.1 - 0.00014 22.0 1.2 0.099 12.9 0.1 3.5 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 EGO25573.1 - 1.3 9.3 4.8 7.3 6.9 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Ferritin_2 PF13668.1 EGO25577.1 - 4.2e-20 72.0 0.0 6.5e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Git3 PF11710.3 EGO25578.1 - 8.4e-10 38.5 11.8 3e-09 36.7 8.1 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGO25578.1 - 0.027 14.2 0.9 0.027 14.2 0.6 2.8 4 0 0 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EGO25578.1 - 0.74 8.6 12.1 2.6 6.8 8.4 1.9 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor DUF423 PF04241.10 EGO25578.1 - 3.8 7.4 7.5 6.7 6.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Cellulase PF00150.13 EGO25579.1 - 2.2e-30 105.8 1.1 3.2e-30 105.2 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nop25 PF09805.4 EGO25580.1 - 3.4e-21 75.7 19.0 3.4e-21 75.7 13.2 2.4 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) V-SNARE_C PF12352.3 EGO25581.1 - 1.6e-14 53.6 0.2 1.6e-14 53.6 0.1 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGO25581.1 - 1.4e-05 24.6 0.8 5.1e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 Sec20 She9_MDM33 PF05546.6 EGO25581.1 - 0.011 15.3 0.6 0.011 15.3 0.4 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family HALZ PF02183.13 EGO25581.1 - 0.023 14.3 1.8 0.19 11.4 0.3 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3513 PF12026.3 EGO25581.1 - 0.04 13.4 1.9 0.06 12.8 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Plasmid_RAQPRD PF09686.5 EGO25581.1 - 0.051 13.6 2.7 0.53 10.4 1.3 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF106 PF01956.11 EGO25581.1 - 0.055 12.9 0.0 0.08 12.4 0.0 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 Wbp11 PF09429.5 EGO25581.1 - 0.11 12.4 3.9 0.68 9.9 2.3 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 Auto_anti-p27 PF06677.7 EGO25582.1 - 1.2e-12 47.3 3.5 1.1e-05 25.1 0.1 2.6 2 1 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.16 EGO25582.1 - 0.6 10.0 2.7 1.3 8.9 0.1 2.4 2 1 0 2 2 2 0 IBR domain Lactamase_B PF00753.22 EGO25584.1 - 5.2e-09 36.0 0.2 7.7e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO25584.1 - 2.7e-05 23.8 0.1 4.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Yae1_N PF09811.4 EGO25585.1 - 1.6e-08 33.9 21.5 9.9e-06 24.9 7.3 3.5 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Effector_1 PF04518.7 EGO25585.1 - 0.0061 15.5 4.7 0.009 15.0 3.3 1.1 1 0 0 1 1 1 1 Effector from type III secretion system Amidohydro_2 PF04909.9 EGO25585.1 - 0.0066 16.0 0.5 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase Fmp27_WPPW PF10359.4 EGO25585.1 - 0.52 8.6 8.4 0.8 8.0 5.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 EGO25585.1 - 1.6 6.5 5.4 2.2 6.0 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 EGO25585.1 - 3.5 7.8 9.1 0.2 11.8 2.5 1.7 2 0 0 2 2 2 0 Syntaxin DUF724 PF05266.9 EGO25585.1 - 4.2 6.9 10.9 3.9 7.0 6.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.1 EGO25585.1 - 9.3 5.3 13.8 7.9 5.6 8.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SNase PF00565.12 EGO25586.1 - 8.9e-56 186.7 0.1 5.2e-20 71.7 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGO25586.1 - 1.1e-21 76.8 0.0 1.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Trp_halogenase PF04820.9 EGO25587.1 - 0.059 11.9 0.0 0.26 9.8 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.11 EGO25588.1 - 1.4e-12 46.9 36.7 6.1e-08 31.7 11.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EGO25588.1 - 0.00026 19.5 5.3 0.00026 19.5 3.7 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein DUF3338 PF11819.3 EGO25589.1 - 0.048 13.1 0.5 0.056 12.8 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) DUF1911 PF08929.5 EGO25589.1 - 0.18 12.4 0.8 0.22 12.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) Dermcidin PF15291.1 EGO25590.1 - 0.13 12.4 4.4 1.8 8.8 0.1 2.3 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide Acetyltransf_1 PF00583.19 EGO25591.1 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGO25591.1 - 0.0041 16.9 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO25591.1 - 0.03 14.4 0.0 0.1 12.7 0.0 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO25591.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UDPGP PF01704.13 EGO25592.1 - 6.7e-178 591.4 3.2 7.9e-178 591.2 2.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Metallophos PF00149.23 EGO25593.1 - 1.2e-11 44.3 0.9 3.8e-11 42.7 0.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UDPGP PF01704.13 EGO25594.1 - 1.7e-169 563.8 0.5 1.5e-168 560.7 0.4 1.9 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_S8e PF01201.17 EGO25595.1 - 2e-50 170.3 1.9 2.6e-50 169.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e NAD_binding_9 PF13454.1 EGO25595.1 - 0.085 12.6 0.1 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding SMAP PF15477.1 EGO25595.1 - 1.2 9.4 4.1 1.2 9.4 0.9 2.5 2 1 0 2 2 2 0 Small acidic protein family Cpn60_TCP1 PF00118.19 EGO25596.1 - 8.3e-152 506.1 0.0 1.1e-151 505.8 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3993 PF13158.1 EGO25597.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) adh_short_C2 PF13561.1 EGO25598.1 - 2.7e-28 99.3 1.7 3.2e-28 99.1 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO25598.1 - 9.2e-27 93.9 1.7 1.3e-26 93.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO25598.1 - 1.2e-12 47.8 2.2 1.2e-11 44.6 1.5 2.0 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EGO25598.1 - 0.0019 18.5 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ARPC4 PF05856.7 EGO25603.1 - 1.7e-75 252.1 4.3 2e-75 251.8 3.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Herpes_UL46 PF03387.9 EGO25603.1 - 0.084 11.0 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL46 protein Gelsolin PF00626.17 EGO25605.1 - 4.4e-09 35.8 0.0 3.4e-05 23.4 0.0 2.6 3 0 0 3 3 3 2 Gelsolin repeat Nse4_C PF08743.5 EGO25607.1 - 6.7e-26 90.1 0.0 1.4e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGO25607.1 - 7.5e-16 57.7 1.4 1.6e-15 56.6 1.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE AXH PF08517.7 EGO25607.1 - 0.17 12.0 0.2 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Ataxin-1 and HBP1 module (AXH) SNF2_N PF00176.18 EGO25608.1 - 4.1e-67 226.0 0.0 6.7e-67 225.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EGO25608.1 - 1.5e-19 69.8 0.0 3.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 EGO25608.1 - 1.5e-17 63.5 0.0 4.5e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.1 EGO25608.1 - 1.5e-08 34.5 7.1 3e-08 33.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO25608.1 - 4.1e-08 32.7 7.3 8.7e-08 31.7 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO25608.1 - 1.2e-07 31.4 5.7 2.5e-07 30.4 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EGO25608.1 - 1.2e-06 28.2 0.0 0.026 14.4 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EGO25608.1 - 1.7e-06 27.6 4.7 3.3e-06 26.7 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO25608.1 - 4e-06 26.3 3.6 7.1e-06 25.5 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO25608.1 - 4.1e-06 26.5 7.6 9.9e-06 25.3 5.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGO25608.1 - 0.002 18.1 3.0 0.0073 16.4 2.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger ResIII PF04851.10 EGO25608.1 - 0.0021 17.9 0.0 0.007 16.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 EGO25608.1 - 0.016 14.9 6.8 0.04 13.6 4.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EGO25608.1 - 0.048 13.4 2.3 0.1 12.3 1.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Gluconate_2-dh3 PF13618.1 EGO25608.1 - 0.68 10.0 4.3 3 7.9 2.2 2.5 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 EPL1 PF10513.4 EGO25608.1 - 1.9 8.6 5.7 0.32 11.2 0.9 2.0 2 0 0 2 2 1 0 Enhancer of polycomb-like NAD_binding_4 PF07993.7 EGO25609.1 - 2.2e-31 108.6 0.0 3.3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGO25609.1 - 4.9e-24 84.4 0.1 2.1e-22 79.1 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGO25609.1 - 7.7e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO25609.1 - 0.00027 20.9 0.0 0.0042 17.1 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO25609.1 - 0.00061 19.7 0.3 0.0039 17.1 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO25609.1 - 0.0023 16.6 0.0 0.0045 15.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EGO25609.1 - 0.0098 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NmrA PF05368.8 EGO25609.1 - 0.016 14.4 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family CUE PF02845.11 EGO25609.1 - 0.17 11.4 0.3 1 8.9 0.0 2.4 2 0 0 2 2 2 0 CUE domain Ribosomal_S7 PF00177.16 EGO25610.1 - 2e-40 137.7 1.0 2.4e-40 137.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4587 PF15248.1 EGO25611.1 - 0.17 12.5 3.9 0.66 10.6 2.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) DUF3533 PF12051.3 EGO25614.1 - 1.5e-80 270.8 11.4 8.9e-64 215.6 1.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) Herpes_UL45 PF05473.7 EGO25614.1 - 0.089 12.2 0.7 0.56 9.6 0.0 2.3 2 1 0 2 2 2 0 UL45 protein zf-RING_2 PF13639.1 EGO25615.1 - 1.1e-11 44.3 3.7 1.8e-09 37.2 0.7 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 EGO25615.1 - 1.3e-07 31.4 3.0 3.3e-07 30.2 0.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO25615.1 - 4.1e-07 30.0 6.6 1.1e-06 28.7 0.1 2.6 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGO25615.1 - 1.2e-06 28.0 0.8 4.8e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25615.1 - 7.1e-06 25.6 1.0 1.8e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO25615.1 - 0.00011 21.8 1.2 0.00027 20.5 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO25615.1 - 0.00068 19.4 0.1 0.00068 19.4 0.1 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGO25615.1 - 0.0063 16.0 0.9 0.015 14.8 0.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EGO25615.1 - 0.0065 16.3 2.2 0.043 13.6 0.3 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EGO25615.1 - 0.1 12.6 0.8 0.21 11.5 0.6 1.5 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.9 EGO25615.1 - 0.13 11.7 0.2 0.37 10.3 0.2 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif FANCL_C PF11793.3 EGO25615.1 - 0.23 11.4 3.4 0.97 9.4 1.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EGO25615.1 - 0.57 10.2 3.2 0.57 10.2 0.5 2.1 2 0 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.1 EGO25615.1 - 4.7 7.0 10.3 0.075 12.7 0.8 2.5 2 1 1 3 3 3 0 RING-type zinc-finger HAD_2 PF13419.1 EGO25616.1 - 7.6e-13 49.0 0.0 9.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO25616.1 - 2.7e-06 26.9 0.1 6.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO25616.1 - 0.00028 21.3 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.12 EGO25617.1 - 1e-09 38.1 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 RRM_2 PF04059.7 EGO25620.1 - 7.6e-33 112.3 1.0 1e-32 111.9 0.7 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 EGO25620.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO25620.1 - 0.0058 16.2 0.1 0.015 14.9 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SapB_1 PF05184.10 EGO25620.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 MIF4G PF02854.14 EGO25621.1 - 3.6e-48 163.7 0.7 3.7e-30 104.8 0.0 3.5 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.9 EGO25621.1 - 3.6e-26 91.9 6.8 3.6e-26 91.9 4.7 2.9 3 0 0 3 3 3 1 Up-frameshift suppressor 2 SNAPc19 PF15497.1 EGO25623.1 - 0.1 12.7 0.7 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Acetyltransf_1 PF00583.19 EGO25624.1 - 8.4e-15 54.5 0.0 5.6e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO25624.1 - 2e-07 30.6 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO25624.1 - 6.4e-05 23.0 0.1 0.0001 22.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO25624.1 - 0.00099 19.2 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO25624.1 - 0.0059 16.5 0.0 0.0076 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO25624.1 - 0.017 15.2 0.1 0.029 14.5 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SHS2_Rpb7-N PF03876.12 EGO25625.1 - 5.3e-07 29.6 0.0 9.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NPR3 PF03666.8 EGO25625.1 - 0.45 8.9 2.6 0.68 8.3 1.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pam16 PF03656.8 EGO25626.1 - 9.9e-22 77.0 1.0 1.4e-13 50.7 0.0 2.4 2 1 0 2 2 2 2 Pam16 Transposase_22 PF02994.9 EGO25627.1 - 0.08 11.4 10.8 0.12 10.8 7.5 1.1 1 0 0 1 1 1 0 L1 transposable element DUF745 PF05335.8 EGO25627.1 - 4.1 6.8 15.9 2.4 7.6 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 EGO25627.1 - 7.5 6.1 17.5 3.1 7.3 5.4 2.5 1 1 1 2 2 2 0 IncA protein PPR_2 PF13041.1 EGO25628.1 - 9.1e-37 124.8 0.7 3.5e-07 30.1 0.0 9.3 4 3 5 10 10 10 8 PPR repeat family PPR_3 PF13812.1 EGO25628.1 - 5.7e-22 76.1 3.0 0.061 13.6 0.0 11.7 12 1 0 12 12 12 5 Pentatricopeptide repeat domain PPR PF01535.15 EGO25628.1 - 1.9e-15 55.6 14.3 0.0051 16.7 0.1 10.3 11 0 0 11 11 11 3 PPR repeat PPR_1 PF12854.2 EGO25628.1 - 4.7e-12 45.1 0.0 0.024 14.1 0.0 7.1 8 0 0 8 8 8 4 PPR repeat ECSIT PF06239.6 EGO25628.1 - 0.0013 17.6 0.1 0.036 12.9 0.1 3.4 3 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway Rad21_Rec8_N PF04825.8 EGO25629.1 - 6.2e-41 138.8 0.1 1.1e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGO25629.1 - 2.7e-12 45.6 0.0 5.6e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGO25629.1 - 0.0077 15.8 0.7 0.14 11.7 0.0 2.5 3 0 0 3 3 3 1 ScpA/B protein NIF PF03031.13 EGO25630.1 - 1.8e-52 177.2 0.0 2.1e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGO25630.1 - 0.069 13.3 0.1 1.6 8.8 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase PTPLA PF04387.9 EGO25631.1 - 1.7e-46 157.6 7.7 3.5e-46 156.6 5.3 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA BRE1 PF08647.6 EGO25632.1 - 0.063 13.2 0.4 0.063 13.2 0.3 2.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.16 EGO25632.1 - 0.074 13.0 3.4 15 5.6 0.1 3.3 3 1 0 3 3 3 0 bZIP transcription factor DUF3166 PF11365.3 EGO25632.1 - 0.11 12.9 1.2 0.49 10.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Tropomyosin_1 PF12718.2 EGO25632.1 - 0.22 11.3 5.8 0.13 12.0 2.4 1.7 2 0 0 2 2 2 0 Tropomyosin like DUF972 PF06156.8 EGO25632.1 - 0.93 9.8 4.4 4.9 7.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 EGO25632.1 - 3.5 7.6 5.1 2.4 8.1 0.2 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat LRR_4 PF12799.2 EGO25634.1 - 1.1e-12 47.2 5.1 5e-05 22.8 2.3 3.9 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO25634.1 - 2.2e-10 40.1 8.1 5e-07 29.3 4.3 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EGO25634.1 - 4.6e-06 25.9 13.2 0.14 12.2 0.3 5.8 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.1 EGO25634.1 - 0.014 14.9 1.7 0.058 12.9 0.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.1 EGO25634.1 - 0.02 14.8 10.8 1 9.6 0.2 4.7 4 1 1 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 EGO25634.1 - 0.21 11.9 11.1 15 6.3 0.1 5.1 5 0 0 5 5 5 0 Leucine rich repeat Arf PF00025.16 EGO25635.1 - 1.3e-77 258.9 0.0 1.5e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGO25635.1 - 3.5e-13 49.2 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGO25635.1 - 9.2e-12 44.5 0.0 1.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGO25635.1 - 1.2e-11 43.9 1.0 1e-07 31.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO25635.1 - 7.8e-10 38.2 0.0 9.3e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO25635.1 - 1.4e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO25635.1 - 0.00013 21.8 0.1 0.00033 20.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO25635.1 - 0.012 15.0 0.0 0.041 13.3 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EGO25635.1 - 0.013 14.5 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase L27 PF02828.11 EGO25635.1 - 0.015 15.0 0.6 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 L27 domain PALP PF00291.20 EGO25636.1 - 1.3e-64 218.4 0.2 1.4e-64 218.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Chitin_synth_1 PF01644.12 EGO25638.1 - 4.6e-79 263.8 0.1 7.5e-79 263.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EGO25638.1 - 6.4e-26 90.8 1.6 1.4e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EGO25638.1 - 1.6e-23 82.1 0.5 4.1e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EGO25638.1 - 1.6e-09 37.7 1.7 6e-09 35.8 0.8 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO25638.1 - 2.5e-09 37.2 0.0 6.8e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 zf-U1 PF06220.7 EGO25639.1 - 1.6e-10 40.3 1.8 2.6e-10 39.6 1.3 1.3 1 0 0 1 1 1 1 U1 zinc finger Barttin PF15462.1 EGO25639.1 - 0.001 18.7 4.2 0.16 11.5 0.3 2.2 2 0 0 2 2 2 2 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-TRM13_CCCH PF11722.3 EGO25639.1 - 1.6 8.1 5.2 3.2 7.2 3.6 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein MFS_1 PF07690.11 EGO25640.1 - 1.8e-16 59.8 32.9 1.8e-16 59.8 22.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0020 PF01170.13 EGO25641.1 - 6.7e-06 25.7 0.0 7.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EGO25641.1 - 0.094 11.7 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase zf-4CXXC_R1 PF10497.4 EGO25642.1 - 4.3e-11 42.8 14.8 6.2e-09 35.9 10.2 2.5 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WHIM2 PF15613.1 EGO25642.1 - 0.02 14.8 0.0 0.075 12.9 0.0 2.1 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Tim17 PF02466.14 EGO25643.1 - 6.2e-31 107.0 6.0 8.1e-31 106.7 4.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyridox_oxidase PF01243.15 EGO25644.1 - 1.1e-11 44.5 0.0 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rad9 PF04139.8 EGO25645.1 - 2.8e-11 43.0 0.0 3.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 NmrA PF05368.8 EGO25646.1 - 5.4e-26 91.2 0.0 6.6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO25646.1 - 7.1e-12 45.6 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO25646.1 - 4.3e-05 23.0 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGO25646.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EGO25646.1 - 0.0021 17.0 0.0 0.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_9 PF13454.1 EGO25647.1 - 0.00013 21.7 0.0 0.00037 20.3 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding HALZ PF02183.13 EGO25648.1 - 0.015 15.0 1.2 0.12 12.1 0.2 2.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 EGO25648.1 - 0.016 14.6 0.7 0.021 14.3 0.5 1.4 1 1 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.3 EGO25648.1 - 0.032 13.9 0.3 0.039 13.6 0.2 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.12 EGO25648.1 - 0.074 13.3 0.2 0.08 13.2 0.1 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EGO25648.1 - 0.11 12.2 0.7 0.25 11.2 0.2 1.7 1 1 1 2 2 2 0 Basic region leucine zipper Mito_fiss_reg PF05308.6 EGO25650.1 - 1.1 8.5 6.0 1.7 7.9 4.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator 2OG-FeII_Oxy_2 PF13532.1 EGO25651.1 - 9.6e-22 77.7 0.0 1.1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UN_NPL4 PF11543.3 EGO25651.1 - 0.037 14.2 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ATP-synt_DE_N PF02823.11 EGO25655.1 - 5.5e-21 74.1 0.5 9.1e-21 73.4 0.3 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GCS PF03074.11 EGO25656.1 - 1.1e-168 561.0 0.0 3.1e-135 451.0 0.0 2.1 1 1 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 EGO25656.1 - 0.0015 17.7 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) APG6 PF04111.7 EGO25657.1 - 1.3e-92 310.2 0.0 1.4e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF4001 PF13165.1 EGO25658.1 - 0.59 9.8 2.7 0.88 9.2 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) Peptidase_C14 PF00656.17 EGO25660.1 - 2.5e-11 43.7 0.0 2.7e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.2 EGO25660.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 CHAT domain IMS PF00817.15 EGO25662.1 - 7.2e-45 152.4 0.0 1.4e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO25662.1 - 2.4e-10 40.4 0.1 6.6e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGO25662.1 - 4.3e-07 29.6 0.1 1.8e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif Rad50_zn_hook PF04423.9 EGO25662.1 - 0.066 12.7 0.8 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif VanZ PF04892.7 EGO25665.1 - 1.4e-07 31.4 4.2 4.5e-07 29.8 2.9 1.8 1 1 0 1 1 1 1 VanZ like family TcpE PF12648.2 EGO25665.1 - 0.0009 19.3 4.1 0.0009 19.3 2.1 1.5 1 1 0 1 1 1 1 TcpE family DUF2339 PF10101.4 EGO25665.1 - 0.003 15.9 0.4 0.0037 15.6 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Polysacc_synt_C PF14667.1 EGO25665.1 - 0.027 14.2 2.2 0.29 10.9 0.3 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Virul_fac_BrkB PF03631.10 EGO25665.1 - 0.032 13.6 2.8 0.041 13.2 1.9 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF1275 PF06912.6 EGO25665.1 - 0.065 12.4 2.6 0.12 11.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) Methyltransf_6 PF03737.10 EGO25666.1 - 9.5e-27 93.7 0.7 1.8e-25 89.6 0.5 2.2 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Ank_5 PF13857.1 EGO25667.1 - 1.1e-15 57.2 0.7 2.9e-09 36.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO25667.1 - 2.9e-14 52.0 0.2 1.2e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGO25667.1 - 6.2e-14 52.0 0.1 1.2e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EGO25667.1 - 9.7e-11 41.5 0.2 5.1e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.1 EGO25667.1 - 1.7e-08 33.9 0.2 0.013 15.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EGO25667.1 - 2.6e-08 34.1 0.1 8.8e-06 26.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ran_BP1 PF00638.13 EGO25668.1 - 0.0022 18.0 1.1 0.0034 17.4 0.7 1.3 1 0 0 1 1 1 1 RanBP1 domain RabGAP-TBC PF00566.13 EGO25669.1 - 3.7e-51 173.6 0.1 5e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.1 EGO25669.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Interleukin 34 YcfA PF07927.7 EGO25670.1 - 0.0024 17.7 0.6 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 YcfA-like protein TFIIA PF03153.8 EGO25670.1 - 0.13 12.1 22.9 0.1 12.4 4.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP_transf PF09830.4 EGO25671.1 - 5.7e-19 67.6 0.0 9.7e-19 66.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EGO25671.1 - 0.048 14.2 0.4 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 HIT domain Imm_superinfect PF14373.1 EGO25673.1 - 0.013 15.1 0.2 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Superinfection immunity protein Lamp PF01299.12 EGO25673.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) ILVD_EDD PF00920.16 EGO25674.1 - 2.7e-195 649.7 0.0 3.1e-195 649.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_11 PF13414.1 EGO25677.1 - 5.2e-19 67.6 3.4 1.2e-10 40.8 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGO25677.1 - 1.5e-15 56.0 0.2 9.4e-05 21.8 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25677.1 - 3.6e-14 51.4 4.0 0.0011 18.6 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO25677.1 - 2.5e-13 50.2 7.6 1.2e-09 38.5 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25677.1 - 6e-09 35.7 5.2 0.00043 20.1 0.4 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO25677.1 - 6.8e-09 34.8 0.3 0.29 11.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25677.1 - 1.1e-08 34.8 6.0 0.0016 18.8 0.0 5.6 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25677.1 - 4.9e-08 32.5 0.1 0.15 12.3 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGO25677.1 - 6.3e-07 29.1 6.6 0.34 10.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25677.1 - 1.1e-06 27.9 0.3 0.047 13.4 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO25677.1 - 3.4e-06 27.3 1.8 0.38 11.1 0.0 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO25677.1 - 0.00051 20.3 3.4 0.42 11.1 0.0 4.8 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO25677.1 - 0.0029 17.4 1.1 0.42 10.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO25677.1 - 0.0085 16.2 0.3 0.031 14.3 0.0 2.2 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGO25677.1 - 0.022 13.8 0.2 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EGO25677.1 - 0.084 12.9 0.0 2.9 8.0 0.0 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EGO25677.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Coatomer epsilon subunit Synuclein PF01387.12 EGO25680.1 - 0.34 10.8 3.1 0.37 10.7 2.2 1.1 1 0 0 1 1 1 0 Synuclein DUF1655 PF07868.6 EGO25681.1 - 0.05 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) Ank_4 PF13637.1 EGO25682.1 - 0.048 14.1 0.0 0.06 13.8 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ETF_alpha PF00766.14 EGO25685.1 - 1.7e-34 117.2 0.8 1e-33 114.8 0.2 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EGO25685.1 - 8.2e-33 113.4 0.0 1.4e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Late_protein_L2 PF00513.13 EGO25685.1 - 0.15 10.8 2.9 0.2 10.4 2.0 1.1 1 0 0 1 1 1 0 Late Protein L2 Pkinase PF00069.20 EGO25686.1 - 2.7e-08 33.2 0.0 3.6e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25686.1 - 0.024 13.6 0.1 0.19 10.7 0.0 2.2 2 1 0 3 3 3 0 Protein tyrosine kinase PepSY_TM_1 PF13172.1 EGO25687.1 - 5 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix Pyr_redox_3 PF13738.1 EGO25691.1 - 1.9e-21 77.0 0.0 5.3e-20 72.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO25691.1 - 5.1e-18 64.5 0.0 5.9e-16 57.7 0.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO25691.1 - 4.9e-15 55.2 0.0 4.3e-09 35.7 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO25691.1 - 1.8e-08 34.5 0.0 2.7e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO25691.1 - 3.4e-06 27.3 0.0 0.00061 20.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO25691.1 - 8.4e-05 22.5 0.0 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO25691.1 - 0.0016 16.9 0.0 0.0087 14.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EGO25691.1 - 0.0019 17.1 0.0 0.046 12.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO25691.1 - 0.021 13.7 0.0 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGO25691.1 - 0.03 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EGO25691.1 - 0.066 12.0 0.2 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EGO25691.1 - 0.066 12.3 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGO25691.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EGO25691.1 - 0.23 10.2 0.0 0.74 8.6 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGO25691.1 - 0.24 11.0 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Baculo_E25 PF05274.6 EGO25692.1 - 0.036 13.6 0.6 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein E25 Pkinase PF00069.20 EGO25693.1 - 2.7e-09 36.5 0.0 3.5e-07 29.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25693.1 - 0.11 11.5 0.0 0.59 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase UBN2_3 PF14244.1 EGO25695.1 - 1.1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO25695.1 - 1.9e-05 23.9 0.1 3.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EGO25695.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pkinase PF00069.20 EGO25699.1 - 5.2e-09 35.6 0.0 6.2e-07 28.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25699.1 - 0.015 14.3 0.1 0.12 11.4 0.0 2.2 2 1 0 2 2 2 0 Protein tyrosine kinase TetR_C_2 PF08361.6 EGO25700.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Pkinase PF00069.20 EGO25701.1 - 3.6e-09 36.1 0.0 4.5e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25701.1 - 0.056 12.5 0.0 0.28 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase RC-P840_PscD PF10657.4 EGO25702.1 - 0.019 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD Abhydrolase_9_N PF15420.1 EGO25702.1 - 2.4 7.8 6.0 3.4 7.3 4.1 1.4 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus RbsD_FucU PF05025.8 EGO25703.1 - 0.029 14.7 1.1 0.05 13.9 0.7 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family DOR PF14839.1 EGO25703.1 - 1.7 8.3 11.4 4.6 6.9 7.9 1.8 1 0 0 1 1 1 0 DOR family Mlp PF03304.8 EGO25704.1 - 0.045 13.7 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family MFS_1 PF07690.11 EGO25705.1 - 6.9e-37 126.9 47.2 6.9e-37 126.9 32.7 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO25705.1 - 6.5e-24 84.0 14.3 9.2e-24 83.5 9.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO25705.1 - 1.1e-14 53.8 10.8 1.1e-14 53.8 7.5 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3094 PF11293.3 EGO25705.1 - 3.7 7.0 8.1 0.4 10.1 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) FMO-like PF00743.14 EGO25706.1 - 5.9e-22 77.5 0.0 2.2e-20 72.3 0.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO25706.1 - 3.1e-21 76.3 0.0 5e-20 72.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO25706.1 - 4.1e-14 52.2 0.0 6.8e-08 31.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO25706.1 - 8.4e-11 42.1 0.0 1.6e-09 37.9 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO25706.1 - 9.9e-06 25.8 0.0 0.0017 18.6 0.0 3.2 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO25706.1 - 2e-05 24.5 0.0 6.3e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO25706.1 - 0.00015 20.8 0.0 0.011 14.6 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO25706.1 - 0.0012 17.3 0.0 0.0063 15.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EGO25706.1 - 0.0014 18.4 0.5 1.6 8.5 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGO25706.1 - 0.0084 15.0 0.0 0.093 11.6 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EGO25706.1 - 0.012 14.7 0.0 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EGO25706.1 - 0.017 13.9 0.0 0.066 12.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGO25706.1 - 0.024 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EGO25706.1 - 0.025 13.4 0.1 0.046 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO25706.1 - 0.07 12.2 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EGO25707.1 - 2.7e-21 76.5 0.0 1.1e-19 71.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO25707.1 - 9.1e-17 60.4 0.1 9.5e-15 53.7 0.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO25707.1 - 6.6e-14 51.5 0.0 3.1e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO25707.1 - 6e-09 36.0 0.0 2.9e-07 30.5 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO25707.1 - 5.1e-06 26.8 0.0 0.00061 20.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO25707.1 - 7.4e-05 22.6 0.0 0.00033 20.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO25707.1 - 0.00038 19.4 0.1 0.046 12.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO25707.1 - 0.002 16.6 0.0 0.0087 14.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EGO25707.1 - 0.0047 15.9 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GHMP_kinases_C PF08544.8 EGO25707.1 - 0.011 15.9 0.0 3.3 7.9 0.0 2.6 1 1 1 2 2 2 0 GHMP kinases C terminal FAD_binding_3 PF01494.14 EGO25707.1 - 0.031 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EGO25707.1 - 0.04 13.0 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EGO25707.1 - 0.043 13.5 1.2 20 4.9 0.0 3.5 3 1 1 4 4 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EGO25707.1 - 0.072 11.9 0.2 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGO25707.1 - 0.11 11.3 0.1 0.74 8.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 EGO25707.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain zf-trcl PF13451.1 EGO25710.1 - 0.59 9.8 5.9 0.32 10.6 3.0 1.4 1 1 0 1 1 1 0 Probable zinc-binding domain Retrotrans_gag PF03732.12 EGO25711.1 - 5.3e-06 26.4 1.9 5.3e-06 26.4 1.3 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO25711.1 - 0.0011 18.7 2.3 0.0019 18.0 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO25712.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-C2H2_jaz PF12171.3 EGO25716.1 - 8.1e-10 38.5 7.5 2.7e-08 33.7 1.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO25716.1 - 1.1e-07 31.8 1.4 1.1e-07 31.8 1.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGO25716.1 - 9.3e-05 22.4 4.1 0.0037 17.3 3.1 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGO25716.1 - 0.00022 21.3 6.6 0.0029 17.8 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-DBF PF07535.7 EGO25716.1 - 0.0075 15.9 0.1 0.0075 15.9 0.1 2.0 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_4 PF13894.1 EGO25716.1 - 0.036 14.4 5.2 0.081 13.2 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 EGO25716.1 - 0.057 11.9 0.6 4.9 5.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 EGO25716.1 - 0.058 13.3 3.0 1.4 8.9 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.7 EGO25716.1 - 0.24 11.1 2.4 1.4 8.6 0.2 2.0 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-LYAR PF08790.6 EGO25716.1 - 0.55 9.9 2.5 13 5.6 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF1279 PF06916.8 EGO25719.1 - 9.1e-18 64.3 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SAM_decarbox PF01536.11 EGO25720.1 - 7e-85 284.6 0.0 1.3e-55 188.4 0.0 2.4 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase PP2C PF00481.16 EGO25722.1 - 3.1e-26 92.3 0.0 1.1e-24 87.2 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGO25722.1 - 0.0013 18.4 0.1 0.22 11.2 0.0 2.7 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Zn_clus PF00172.13 EGO25723.1 - 7.1e-07 29.0 22.5 7.1e-05 22.6 9.6 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Dfp1_Him1_M PF08630.5 EGO25725.1 - 4.7e-21 74.8 0.0 1.9e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EGO25725.1 - 3.4e-20 71.4 0.2 6.9e-20 70.4 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EGO25725.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ZapA PF05164.8 EGO25725.1 - 0.066 13.1 1.0 3.2 7.7 0.0 2.7 3 0 0 3 3 3 0 Cell division protein ZapA PTCB-BRCT PF12738.2 EGO25725.1 - 0.2 11.5 0.6 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 twin BRCT domain HK97-gp10_like PF04883.7 EGO25725.1 - 0.44 11.5 7.7 0.13 13.2 2.7 2.0 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Spc97_Spc98 PF04130.8 EGO25726.1 - 1.2e-45 155.9 0.6 1.9e-45 155.2 0.4 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF4530 PF15039.1 EGO25728.1 - 0.12 12.2 0.2 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) TP6A_N PF04406.9 EGO25729.1 - 1.3e-20 72.8 0.0 2.3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase F-box-like PF12937.2 EGO25730.1 - 0.04 13.6 0.1 11 5.8 0.0 2.7 2 0 0 2 2 2 0 F-box-like Ctr PF04145.10 EGO25731.1 - 5.2e-41 140.0 0.2 6.2e-41 139.8 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Herpes_LAMP2 PF06126.6 EGO25731.1 - 1.1 7.5 4.5 0.2 10.0 0.1 1.7 2 0 0 2 2 2 0 Herpesvirus Latent membrane protein 2 2TM PF13239.1 EGO25731.1 - 1.4 8.9 4.8 0.65 10.0 0.1 2.0 2 0 0 2 2 2 0 2TM domain DUF2628 PF10947.3 EGO25731.1 - 8.7 6.1 7.6 19 5.1 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Proteasome PF00227.21 EGO25732.1 - 1.3e-53 181.0 0.0 1.9e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO25732.1 - 2.2e-14 52.4 0.2 4.1e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SKI PF01202.17 EGO25733.1 - 1.5e-10 41.2 0.0 7.3e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Shikimate kinase AAA_17 PF13207.1 EGO25733.1 - 8.1e-08 33.1 0.0 1.2e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO25733.1 - 8.9e-07 29.2 0.0 7.5e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO25733.1 - 1.1e-05 25.3 0.0 5.8e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGO25733.1 - 0.0077 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Cytidylate_kin2 PF13189.1 EGO25733.1 - 0.013 15.4 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_29 PF13555.1 EGO25733.1 - 0.023 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO25733.1 - 0.025 14.5 0.1 0.049 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EGO25733.1 - 0.028 14.0 0.5 0.045 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EGO25733.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 EGO25733.1 - 0.045 13.8 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO25733.1 - 0.054 13.4 0.3 0.099 12.5 0.1 1.7 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGO25733.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EGO25733.1 - 0.075 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGO25733.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 EGO25733.1 - 0.16 11.6 0.2 0.81 9.2 0.0 2.2 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 EGO25733.1 - 0.16 10.9 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FMO-like PF00743.14 EGO25735.1 - 2.4e-22 78.8 0.4 5.9e-18 64.3 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO25735.1 - 6.9e-21 75.2 0.0 5.1e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO25735.1 - 2e-14 53.2 0.0 6.5e-08 31.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO25735.1 - 8.2e-10 38.8 0.0 7.6e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO25735.1 - 6.2e-07 29.7 0.0 0.00032 21.0 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO25735.1 - 4.2e-05 23.4 0.0 0.00016 21.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO25735.1 - 0.00048 19.1 0.0 0.027 13.3 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO25735.1 - 0.00074 19.3 0.2 0.28 10.9 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGO25735.1 - 0.002 17.1 0.3 0.067 12.0 0.2 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EGO25735.1 - 0.0056 15.1 0.0 0.01 14.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 EGO25735.1 - 0.0098 15.0 0.1 0.029 13.5 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EGO25735.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGO25735.1 - 0.032 13.0 0.1 0.13 11.0 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGO25735.1 - 0.044 12.6 0.3 0.073 11.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO25735.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family TatD_DNase PF01026.16 EGO25736.1 - 5.7e-51 173.1 0.0 7.2e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase NPCBM PF08305.6 EGO25737.1 - 0.05 13.5 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 NPCBM/NEW2 domain Nuc_rec_co-act PF08815.5 EGO25737.1 - 0.093 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator Calpain_inhib PF00748.14 EGO25737.1 - 0.15 12.3 1.4 0.36 11.1 0.9 1.7 2 0 0 2 2 2 0 Calpain inhibitor MFS_1 PF07690.11 EGO25739.1 - 1.6e-16 60.0 36.0 2.6e-16 59.3 25.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO25739.1 - 2.8e-14 52.8 6.6 2.8e-14 52.8 4.5 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Methyltransf_31 PF13847.1 EGO25741.1 - 2.2e-15 56.5 0.1 4.6e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO25741.1 - 1.6e-12 47.9 0.0 3.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO25741.1 - 4.1e-12 45.8 0.0 6.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGO25741.1 - 7.2e-11 42.4 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO25741.1 - 3.4e-09 36.7 0.0 9e-09 35.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO25741.1 - 7.3e-09 35.5 0.0 1.8e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGO25741.1 - 7e-08 31.5 0.0 1.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EGO25741.1 - 1.1e-07 31.4 0.1 1.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO25741.1 - 1.7e-07 31.6 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO25741.1 - 6.6e-07 28.6 0.0 9.4e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGO25741.1 - 1.2e-06 28.7 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGO25741.1 - 2.8e-06 26.5 0.0 3.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.13 EGO25741.1 - 4.5e-05 22.6 0.0 7.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 EGO25741.1 - 0.00015 21.0 0.3 0.00046 19.4 0.2 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 EGO25741.1 - 0.00017 21.6 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EGO25741.1 - 0.00035 20.1 0.1 0.00056 19.5 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGO25741.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGO25741.1 - 0.00092 18.7 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EGO25741.1 - 0.00098 19.9 0.0 0.0022 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGO25741.1 - 0.0036 16.9 0.1 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGO25741.1 - 0.042 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_2 PF00891.13 EGO25741.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF2367 PF10164.4 EGO25743.1 - 5.2e-07 29.4 0.3 1.1e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) GCP5-Mod21 PF14609.1 EGO25744.1 - 0.4 8.7 3.2 0.48 8.4 2.2 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 4HB_MCP_1 PF12729.2 EGO25746.1 - 0.026 13.8 0.4 0.033 13.5 0.3 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Mucin PF01456.12 EGO25747.1 - 0.024 14.3 1.9 0.03 14.0 1.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein PAC2 PF09754.4 EGO25749.1 - 4.6e-25 88.7 0.0 5.4e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 PAC2 family NUC173 PF08161.7 EGO25750.1 - 2.5e-40 137.9 0.1 2e-38 131.7 0.1 2.5 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 EGO25750.1 - 1.8e-05 24.3 0.5 0.52 10.5 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EGO25750.1 - 0.00081 19.8 0.5 9.4 6.8 0.0 5.4 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EGO25750.1 - 0.0022 18.2 5.4 4.8 7.5 0.0 5.7 6 1 0 6 6 6 2 HEAT repeats Aminotran_5 PF00266.14 EGO25750.1 - 0.087 11.5 0.4 0.16 10.6 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Acyltransferase PF01553.16 EGO25751.1 - 5.1e-15 55.0 0.0 1.5e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase ABC2_membrane PF01061.19 EGO25751.1 - 0.087 11.9 10.8 0.2 10.8 4.0 2.2 2 0 0 2 2 2 0 ABC-2 type transporter FAD_binding_3 PF01494.14 EGO25753.1 - 3.2e-15 56.0 0.0 6e-14 51.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EGO25753.1 - 0.087 11.6 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Choline_transpo PF04515.7 EGO25754.1 - 1.6e-94 316.4 13.0 1.6e-94 316.4 9.0 1.7 2 0 0 2 2 2 1 Plasma-membrane choline transporter PP2C PF00481.16 EGO25755.1 - 2.2e-63 214.0 5.8 2.1e-50 171.5 0.2 2.7 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.7 EGO25755.1 - 6.2e-05 22.7 0.4 0.00037 20.2 0.3 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) W2 PF02020.13 EGO25756.1 - 1.2e-13 50.8 0.1 3.8e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_clus PF00172.13 EGO25757.1 - 6.5e-08 32.3 12.3 1.2e-07 31.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO25757.1 - 1.3e-06 27.5 0.0 2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.14 EGO25759.1 - 1.9e-215 716.3 0.0 2.5e-215 715.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGO25759.1 - 1.9e-17 62.8 0.1 5.3e-17 61.4 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGO25759.1 - 9.4e-05 22.0 2.8 0.00035 20.2 1.9 2.1 1 0 0 1 1 1 1 DHHA1 domain Ribosomal_L34 PF00468.12 EGO25760.1 - 1.7e-15 56.3 12.2 2.5e-15 55.8 8.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Ribosomal_S13 PF00416.17 EGO25761.1 - 4.2e-41 139.7 1.3 5.1e-41 139.4 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGO25761.1 - 0.016 13.7 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EGO25761.1 - 0.15 12.0 0.4 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 CBFB_NFYA PF02045.10 EGO25763.1 - 5.8e-30 103.6 6.8 6.7e-30 103.4 4.7 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B HeH PF12949.2 EGO25764.1 - 1.5e-05 24.4 0.7 1.5e-05 24.4 0.5 2.2 2 0 0 2 2 2 1 HeH/LEM domain Rho_N PF07498.7 EGO25764.1 - 0.0016 18.1 0.2 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.22 EGO25764.1 - 0.045 13.2 0.5 0.26 10.8 0.2 2.4 2 1 0 2 2 2 0 SAP domain Armet PF10208.4 EGO25764.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Hep_59 PF07052.6 EGO25764.1 - 0.37 11.1 6.3 0.36 11.2 1.5 2.4 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 peroxidase PF00141.18 EGO25767.1 - 4.7e-46 157.1 0.0 7.6e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DeoC PF01791.4 EGO25767.1 - 0.03 13.6 0.1 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase Muskelin_N PF06588.6 EGO25768.1 - 1.7e-59 200.8 0.0 2.7e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 EGO25768.1 - 5.9e-32 109.0 3.6 2.3e-11 43.5 0.0 7.8 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGO25768.1 - 4e-30 103.3 5.1 1.8e-11 43.6 0.0 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO25768.1 - 9e-23 79.7 5.3 2.3e-08 33.7 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EGO25768.1 - 5.2e-20 70.7 6.8 3.3e-06 27.0 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 EGO25768.1 - 4.5e-18 64.5 3.5 5.2e-08 32.3 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EGO25768.1 - 3.3e-07 29.8 9.0 0.00012 21.7 0.2 5.1 5 1 0 5 5 5 2 Kelch motif Sad1_UNC PF07738.8 EGO25768.1 - 0.0065 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Prefoldin_2 PF01920.15 EGO25769.1 - 1.2e-19 70.0 7.8 1.6e-19 69.6 5.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit TPR_11 PF13414.1 EGO25769.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 TPR repeat Prefoldin PF02996.12 EGO25769.1 - 0.1 12.2 8.1 0.064 12.9 1.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF2540 PF10802.3 EGO25769.1 - 0.15 11.7 1.9 0.73 9.5 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2540) Laminin_II PF06009.7 EGO25769.1 - 0.23 11.2 3.3 0.16 11.7 0.9 1.7 2 0 0 2 2 2 0 Laminin Domain II AAA_23 PF13476.1 EGO25769.1 - 0.71 10.1 7.5 0.93 9.7 5.2 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EGO25769.1 - 1.5 7.1 5.0 1.7 6.9 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 EGO25769.1 - 1.6 8.6 4.9 1.1 9.2 1.0 2.5 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 EGO25769.1 - 2.3 5.9 6.0 2.5 5.8 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EGO25769.1 - 4.3 6.9 9.1 4.4 6.8 1.9 2.2 1 1 1 2 2 2 0 Septum formation initiator Viral_P18 PF04521.8 EGO25769.1 - 8.5 5.8 7.1 6.4 6.2 1.3 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FTA4 PF13093.1 EGO25769.1 - 9.9 5.5 12.0 14 5.0 8.3 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Pyridoxal_deC PF00282.14 EGO25770.1 - 6e-15 54.5 0.0 1.1e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGO25770.1 - 3.2e-09 36.0 0.0 1.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGO25770.1 - 0.0016 17.5 0.1 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_N PF00339.24 EGO25773.1 - 5.4e-07 29.5 0.0 2.3e-06 27.5 0.0 1.7 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EGO25773.1 - 4.4e-06 26.3 0.0 5.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4218 PF13960.1 EGO25774.1 - 0.00021 20.7 0.0 0.00051 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ATP-synt_DE PF00401.15 EGO25778.1 - 0.061 13.2 1.6 0.12 12.2 1.1 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain EF-hand_4 PF12763.2 EGO25780.1 - 9.2e-14 51.0 0.0 9.1e-09 35.0 0.0 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 EGO25781.1 - 1.7e-21 75.1 2.0 8.2e-10 38.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 EGO25781.1 - 0.0013 18.4 1.0 0.01 15.6 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO25781.1 - 0.0032 17.4 1.2 0.0089 16.0 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO25781.1 - 0.047 13.3 3.3 0.13 11.8 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGO25781.1 - 0.052 13.3 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.1 EGO25781.1 - 0.095 12.4 3.9 0.4 10.4 2.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.27 EGO25782.1 - 1.5e-15 56.3 4.6 5.4e-11 41.9 0.1 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nbas_N PF15492.1 EGO25782.1 - 0.072 12.1 0.0 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Mid2 PF04478.7 EGO25783.1 - 0.074 12.4 0.1 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 EGO25783.1 - 2.8 7.3 9.1 0.43 9.9 3.5 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Phage_Gp15 PF06854.6 EGO25784.1 - 0.067 12.7 0.1 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage Gp15 protein PLATZ PF04640.9 EGO25784.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 PLATZ transcription factor Exo_endo_phos PF03372.18 EGO25788.1 - 1.3e-21 77.7 0.2 1.8e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 EGO25788.1 - 4.3e-17 61.6 20.5 4.8e-09 35.8 1.3 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EGO25788.1 - 6.5e-17 60.7 7.5 8.9e-09 34.7 1.4 3.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO25788.1 - 1.5e-08 33.5 6.6 0.0095 15.8 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EGO25788.1 - 1.5e-05 24.4 7.0 1.1 9.8 0.0 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EGO25788.1 - 0.064 13.3 4.6 6.2 7.2 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat GHMP_kinases_N PF00288.21 EGO25789.1 - 2.7e-08 33.7 3.7 5.5e-08 32.7 2.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain F-box-like PF12937.2 EGO25790.1 - 4.4e-07 29.5 0.9 2.2e-06 27.3 0.7 2.2 1 1 0 1 1 1 1 F-box-like COG5 PF10392.4 EGO25791.1 - 0.031 14.2 0.5 0.043 13.7 0.3 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Pkinase PF00069.20 EGO25792.1 - 4.1e-40 137.5 0.0 6e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25792.1 - 4e-35 121.1 0.0 7e-35 120.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO25792.1 - 0.0014 18.4 0.1 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3844 PF12955.2 EGO25794.1 - 8.4e-31 106.1 4.1 1.3e-30 105.5 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EGO25794.1 - 1.5 9.0 11.8 2.7 8.2 8.2 1.5 1 0 0 1 1 1 0 EGF-like domain Lipocalin_4 PF13648.1 EGO25795.1 - 3.5 8.2 12.9 5.3 7.7 0.2 3.2 4 0 0 4 4 4 0 Lipocalin-like domain Trypan_PARP PF05887.6 EGO25798.1 - 0.00071 19.4 0.8 0.0013 18.5 0.6 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) I-set PF07679.11 EGO25798.1 - 0.11 12.3 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin I-set domain Lipocalin_4 PF13648.1 EGO25798.1 - 0.27 11.8 9.7 1.4 9.6 0.4 2.5 2 0 0 2 2 2 0 Lipocalin-like domain Mito_carr PF00153.22 EGO25800.1 - 2.8e-76 251.3 0.7 1.5e-26 91.8 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_63 PF03200.11 EGO25801.1 - 2.1e-06 25.9 9.3 9.5e-06 23.7 1.1 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase BRCT PF00533.21 EGO25802.1 - 0.00028 20.9 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_2 PF08914.6 EGO25803.1 - 0.25 11.1 0.1 0.25 11.1 0.1 1.7 2 0 0 2 2 2 0 Rap1 Myb domain PhyH PF05721.8 EGO25804.1 - 3.3e-44 151.4 0.0 5.9e-44 150.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HK PF02110.10 EGO25805.1 - 3.4e-76 255.6 1.0 5.4e-70 235.3 0.9 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EGO25805.1 - 1.2e-53 180.9 0.2 2.5e-53 179.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI p450 PF00067.17 EGO25806.1 - 8.9e-61 205.8 0.0 1.1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MASE2 PF05230.6 EGO25807.1 - 0.083 12.8 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 MASE2 domain PD-C2-AF1 PF09310.5 EGO25809.1 - 0.055 12.6 0.2 0.15 11.1 0.2 1.6 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 DUF4184 PF13803.1 EGO25810.1 - 0.091 12.0 4.9 0.74 9.0 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) DUF2231 PF09990.4 EGO25810.1 - 0.49 10.7 5.2 6.4 7.1 1.5 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) ADH_zinc_N PF00107.21 EGO25811.1 - 1.9e-22 79.1 0.2 3.1e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO25811.1 - 8.4e-10 39.6 0.0 1.6e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 EGO25811.1 - 0.0008 18.6 0.1 0.021 13.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) TrkA_N PF02254.13 EGO25811.1 - 0.047 13.6 0.1 0.4 10.6 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_10 PF13460.1 EGO25811.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding SUR7 PF06687.7 EGO25812.1 - 2.7e-16 59.7 12.2 7.3e-16 58.3 8.5 1.7 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EGO25812.1 - 4.6e-06 26.4 12.1 4.6e-05 23.1 4.4 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 EGO25812.1 - 0.0018 17.9 4.9 0.0028 17.2 3.4 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein Clc-like PF07062.7 EGO25812.1 - 0.13 11.4 9.1 0.051 12.8 3.9 2.0 1 1 0 1 1 1 0 Clc-like DUF2301 PF10063.4 EGO25812.1 - 4.5 7.4 7.3 0.41 10.8 0.7 2.3 2 1 1 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) DUF1772 PF08592.6 EGO25812.1 - 7.3 6.3 13.7 0.58 9.8 3.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF747 PF05346.6 EGO25815.1 - 2.7e-114 381.7 6.4 3.3e-114 381.4 4.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family F-box-like PF12937.2 EGO25817.1 - 6e-05 22.6 0.0 0.00019 21.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO25817.1 - 0.028 14.0 1.4 0.54 9.9 0.0 2.8 3 0 0 3 3 3 0 F-box domain p450 PF00067.17 EGO25818.1 - 9.4e-33 113.4 0.0 4.9e-32 111.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EGO25819.1 - 4.5e-18 65.0 0.1 1e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO25819.1 - 2.5e-12 46.5 0.0 4.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGO25819.1 - 6.9e-05 23.7 0.0 0.00055 20.8 0.0 2.2 2 1 1 3 3 3 1 Zinc-binding dehydrogenase CI-B14_5a PF07347.7 EGO25820.1 - 0.032 14.0 0.2 0.055 13.2 0.2 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) G_glu_transpept PF01019.16 EGO25824.1 - 0.072 11.5 1.6 0.088 11.2 1.1 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.16 EGO25825.1 - 5.5e-135 450.7 0.0 6.1e-135 450.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_A22B PF04258.8 EGO25826.1 - 1e-68 232.0 0.9 1.2e-68 231.7 0.6 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGO25826.1 - 1.1e-05 24.7 3.9 4.1e-05 22.8 2.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) Sec7 PF01369.15 EGO25829.1 - 5e-39 133.9 0.4 8.6e-39 133.1 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGO25829.1 - 3.1e-27 95.0 0.0 6.7e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain GATA PF00320.22 EGO25829.1 - 1.7e-18 65.6 2.3 3.9e-18 64.4 1.6 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EGO25829.1 - 9.2e-13 47.5 2.5 2.4e-12 46.2 1.8 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Lzipper-MIP1 PF14389.1 EGO25829.1 - 0.051 13.6 1.7 0.12 12.5 1.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_hydro_76 PF03663.9 EGO25830.1 - 3.5e-41 141.8 28.6 4.5e-41 141.4 19.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CPSF73-100_C PF11718.3 EGO25832.1 - 8.4e-55 185.4 0.0 1.2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EGO25832.1 - 2.1e-32 111.7 0.0 1.1e-31 109.4 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EGO25832.1 - 2.2e-14 53.5 0.3 1e-13 51.3 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EGO25832.1 - 4.4e-10 39.2 0.1 9.3e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGO25832.1 - 1.4e-09 37.7 0.3 1.4e-09 37.7 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO25832.1 - 4.8e-07 29.6 0.3 9.7e-06 25.3 0.0 2.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Retrotrans_gag PF03732.12 EGO25833.1 - 0.013 15.5 0.1 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Nop14 PF04147.7 EGO25837.1 - 0.012 13.5 0.4 0.013 13.4 0.3 1.0 1 0 0 1 1 1 0 Nop14-like family COG7 PF10191.4 EGO25837.1 - 0.069 11.0 1.2 0.075 10.9 0.8 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Tombus_movement PF05318.7 EGO25837.1 - 1.9 9.1 5.5 2.7 8.6 3.2 1.7 2 0 0 2 2 2 0 Tombusvirus movement protein Rnk_N PF14760.1 EGO25838.1 - 0.014 15.4 0.7 3.4 7.8 0.2 2.4 2 0 0 2 2 2 0 Rnk N-terminus RrnaAD PF00398.15 EGO25841.1 - 3.5e-20 72.1 0.0 5.8e-20 71.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.21 EGO25842.1 - 5.9e-12 45.2 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO25842.1 - 4.6e-11 42.4 0.0 7.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGO25842.1 - 0.017 15.9 0.0 0.051 14.4 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO25844.1 - 8.5e-13 48.0 0.0 2.1e-12 46.7 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO25844.1 - 2.1e-12 46.7 0.0 3.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transpos_assoc PF13963.1 EGO25846.1 - 0.068 13.1 0.6 0.21 11.5 0.4 1.9 1 0 0 1 1 1 0 Transposase-associated domain NiFeSe_Hases PF00374.14 EGO25847.1 - 0.064 12.0 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Nucleocap_ssRNA PF11128.3 EGO25847.1 - 0.066 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid ADH_N PF08240.7 EGO25849.1 - 3.2e-09 36.4 0.0 5.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO25849.1 - 8.1e-09 35.1 0.0 2.1e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO25849.1 - 0.021 15.7 0.0 0.036 14.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase OmdA PF13376.1 EGO25849.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated ADH_N PF08240.7 EGO25851.1 - 1.2e-12 47.5 0.4 3.5e-12 46.0 0.0 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO25851.1 - 4.2e-11 42.5 0.0 7.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RRM_1 PF00076.17 EGO25852.1 - 6.8e-12 44.8 0.1 7e-05 22.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO25852.1 - 3.5e-09 36.5 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO25852.1 - 1.4e-06 28.0 0.0 4.1e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO25852.1 - 0.0031 17.2 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PI3_PI4_kinase PF00454.22 EGO25853.1 - 4.1e-28 98.4 0.0 1.7e-27 96.3 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase SLAC1 PF03595.12 EGO25854.1 - 7.2e-77 258.2 51.9 8.2e-77 258.0 36.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 EGO25855.1 - 3.2e-76 256.1 46.7 3.6e-76 255.9 32.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3353 PF11833.3 EGO25855.1 - 1.4 8.3 7.7 0.35 10.2 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Inhibitor_I9 PF05922.11 EGO25857.1 - 0.0017 18.8 0.0 0.0027 18.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 Inhibitor_I9 PF05922.11 EGO25858.1 - 2.2e-05 24.9 0.0 3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 HhH-GPD PF00730.20 EGO25859.1 - 2.2e-10 40.7 0.0 1e-08 35.4 0.0 2.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2638 PF10937.3 EGO25859.1 - 4.9 8.2 7.5 0.81 10.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2638) Pkinase PF00069.20 EGO25860.1 - 1.2e-37 129.5 0.0 1.4e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25860.1 - 2.3e-14 53.0 0.0 3.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO25860.1 - 7.7e-06 25.0 0.0 9.8e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO25860.1 - 0.00086 19.1 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO25860.1 - 0.0029 16.6 0.1 0.0042 16.1 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_q6 PF01058.17 EGO25861.1 - 2e-22 79.2 0.1 3e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mnd1 PF03962.10 EGO25863.1 - 1.5e-56 191.0 0.1 1.7e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Mnd1 family FUR PF01475.14 EGO25863.1 - 0.005 16.7 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Ferric uptake regulator family Penicillinase_R PF03965.11 EGO25863.1 - 0.013 15.5 0.0 0.059 13.4 0.0 2.1 2 1 0 2 2 2 0 Penicillinase repressor TrmB PF01978.14 EGO25863.1 - 0.016 14.8 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB GntR PF00392.16 EGO25863.1 - 0.099 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family IncA PF04156.9 EGO25863.1 - 1.4 8.4 6.0 0.15 11.6 1.3 1.4 2 0 0 2 2 2 0 IncA protein Myb_DNA-bind_4 PF13837.1 EGO25865.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Surp PF01805.15 EGO25865.1 - 0.18 11.4 0.6 0.4 10.3 0.2 1.7 1 1 1 2 2 2 0 Surp module NB-ARC PF00931.17 EGO25866.1 - 7.6e-07 28.2 0.0 9.2e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EGO25866.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO25866.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGO25866.1 - 0.0031 17.1 0.1 0.027 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGO25866.1 - 0.0071 16.0 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EGO25866.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGO25866.1 - 0.027 14.1 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EGO25866.1 - 0.061 12.2 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EGO25866.1 - 0.064 12.6 0.0 0.091 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGO25866.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EGO25866.1 - 0.076 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EGO25866.1 - 0.093 11.8 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EGO25866.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Autophagy_N PF03986.8 EGO25867.1 - 2.7e-45 153.7 0.1 5.2e-45 152.7 0.1 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGO25867.1 - 9.4e-25 86.5 0.2 1.7e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EGO25867.1 - 3.7e-12 45.1 3.2 6.8e-12 44.2 2.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal TPR_14 PF13428.1 EGO25868.1 - 7.2e-23 79.0 22.1 0.0009 19.6 0.0 12.6 4 2 9 13 13 13 5 Tetratricopeptide repeat HAT PF02184.11 EGO25868.1 - 6.6e-20 70.5 53.2 3.6e-08 33.0 2.8 12.6 12 2 0 12 12 11 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EGO25868.1 - 5.8e-14 52.1 0.1 0.15 12.3 0.0 6.5 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25868.1 - 4.7e-13 47.9 0.7 0.14 12.1 0.0 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO25868.1 - 8.9e-10 38.0 0.5 0.1 12.2 0.0 6.1 4 2 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 EGO25868.1 - 2.7e-09 37.4 21.7 0.0009 19.8 0.0 8.0 4 2 6 11 11 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25868.1 - 1.4e-07 31.1 0.2 0.0012 18.9 0.1 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25868.1 - 1.6e-07 31.1 9.0 0.11 12.4 0.1 6.4 5 2 1 6 6 5 2 Tetratricopeptide repeat SNAP PF14938.1 EGO25868.1 - 3.3e-07 29.7 1.3 7.5e-05 22.0 0.4 3.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EGO25868.1 - 3.3e-06 26.4 5.3 0.55 10.1 0.0 7.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGO25868.1 - 6.8e-06 25.3 19.9 0.026 13.6 3.3 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25868.1 - 7.6e-06 25.3 0.1 5.3 6.8 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGO25868.1 - 4.3e-05 23.2 16.0 1 9.1 0.1 6.8 4 2 0 5 5 5 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 EGO25868.1 - 8.6e-05 22.0 0.4 13 5.7 0.0 6.0 5 2 2 7 7 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EGO25868.1 - 0.0088 15.7 15.3 0.033 13.9 0.4 5.9 4 3 1 5 5 5 1 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 EGO25868.1 - 0.036 13.9 1.6 21 5.0 0.1 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EGO25868.1 - 0.17 12.0 6.6 6.2 7.0 0.1 4.6 4 1 1 5 5 5 0 c-SKI Smad4 binding domain DUF3836 PF12930.2 EGO25868.1 - 0.91 9.0 5.7 9.7 5.6 1.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF3836) TPR_6 PF13174.1 EGO25868.1 - 2 9.0 12.6 72 4.1 0.0 7.6 8 2 1 9 9 7 0 Tetratricopeptide repeat Lipase_3 PF01764.20 EGO25869.1 - 2.9e-22 78.8 0.0 4.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGO25869.1 - 0.029 14.2 0.3 0.11 12.3 0.2 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF2048 PF09752.4 EGO25869.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_5 PF12695.2 EGO25869.1 - 0.14 11.8 0.1 0.23 11.2 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pec_lyase_N PF04431.8 EGO25870.1 - 0.016 15.3 0.1 0.031 14.3 0.1 1.6 1 1 0 1 1 1 0 Pectate lyase, N terminus Gti1_Pac2 PF09729.4 EGO25874.1 - 7.2e-21 74.7 0.1 2.6e-17 63.2 0.0 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family Gti1_Pac2 PF09729.4 EGO25877.1 - 1.6e-27 96.4 0.1 2.4e-22 79.6 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family VKOR PF07884.9 EGO25878.1 - 0.11 12.2 0.6 0.11 12.2 0.4 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Cas_CXXC_CXXC PF09706.5 EGO25878.1 - 0.12 12.5 1.1 0.18 12.0 0.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) tRNA-synt_1e PF01406.14 EGO25879.1 - 2.6e-128 427.3 0.1 4.6e-128 426.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGO25879.1 - 2.4e-09 36.3 0.5 9.8e-06 24.4 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGO25879.1 - 5.5e-07 27.9 1.5 0.00012 20.3 0.0 2.9 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EGO25879.1 - 3.8e-05 23.8 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 DALR domain GLTP PF08718.6 EGO25881.1 - 2.3e-41 141.3 0.0 3e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Codanin-1_C PF15296.1 EGO25881.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Codanin-1 C-terminus DUF3050 PF11251.3 EGO25881.1 - 0.053 12.7 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) bZIP_2 PF07716.10 EGO25884.1 - 3.8e-10 39.4 12.2 3.8e-10 39.4 8.5 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EGO25884.1 - 1.1e-05 25.2 12.3 3.1e-05 23.8 8.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EGO25884.1 - 0.005 16.7 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Haemolysin XhlA CASP_C PF08172.7 EGO25884.1 - 0.016 14.2 0.3 0.026 13.5 0.2 1.3 1 0 0 1 1 1 0 CASP C terminal PGBA_C PF15437.1 EGO25884.1 - 0.028 14.5 8.6 0.035 14.2 2.8 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal TSC22 PF01166.13 EGO25884.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 EGO25884.1 - 2.9 8.2 9.0 0.42 10.9 2.9 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Pap_E4 PF02711.9 EGO25884.1 - 9.3 7.1 11.7 0.11 13.3 1.4 2.6 1 1 2 3 3 3 0 E4 protein PSD4 PF07631.6 EGO25885.1 - 0.17 12.2 0.7 0.37 11.1 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) Arf PF00025.16 EGO25887.1 - 7.7e-37 126.1 0.0 1.5e-36 125.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGO25887.1 - 8.9e-11 41.0 0.0 8.4e-06 24.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO25887.1 - 2.4e-07 30.1 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO25887.1 - 3.2e-07 30.8 0.0 4.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGO25887.1 - 7.2e-07 28.7 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGO25887.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO25887.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO25887.1 - 0.00089 18.7 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EGO25887.1 - 0.0018 18.5 0.3 0.003 17.8 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EGO25887.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGO25887.1 - 0.0087 16.4 0.5 0.01 16.1 0.4 1.4 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EGO25887.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EGO25887.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 EGO25887.1 - 0.011 15.1 0.0 0.056 12.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rhomboid_SP PF12595.3 EGO25887.1 - 0.015 14.9 0.4 0.022 14.3 0.3 1.2 1 0 0 1 1 1 0 Rhomboid serine protease Thymidylate_kin PF02223.12 EGO25887.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 EGO25887.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO25887.1 - 0.037 14.8 2.2 0.079 13.7 1.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGO25887.1 - 0.051 13.4 0.3 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGO25887.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EGO25887.1 - 0.057 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EGO25887.1 - 0.067 12.1 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.1 EGO25887.1 - 0.068 13.1 0.1 0.18 11.7 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EGO25887.1 - 0.085 12.5 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EGO25887.1 - 0.099 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 EGO25887.1 - 0.12 12.3 0.1 0.21 11.5 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO25887.1 - 0.23 11.7 4.0 0.73 10.1 2.7 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 EGO25888.1 - 1e-25 89.3 33.2 9.3e-16 57.4 6.4 2.6 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 EGO25888.1 - 0.021 15.0 0.4 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Rubis-subs-bind PF09273.6 EGO25889.1 - 1.2e-10 41.3 0.1 2.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EGO25889.1 - 9.2e-09 35.8 0.0 2.1e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 SET domain FAD_binding_3 PF01494.14 EGO25890.1 - 2.3e-17 63.1 0.0 4e-17 62.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGO25890.1 - 9.1e-09 34.6 0.1 3.3e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EGO25890.1 - 6.9e-08 31.5 0.3 1.4e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 EGO25890.1 - 1.5e-07 30.6 0.3 5.6e-06 25.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO25890.1 - 9.1e-07 28.8 0.3 2.2e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGO25890.1 - 1.7e-06 27.4 0.1 0.0014 17.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EGO25890.1 - 3.8e-06 25.9 1.1 8.2e-06 24.9 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO25890.1 - 2.9e-05 23.2 0.1 5.7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGO25890.1 - 6.1e-05 23.3 0.8 0.0017 18.6 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO25890.1 - 0.00037 20.4 0.3 0.0011 18.9 0.3 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO25890.1 - 0.0014 17.2 0.5 0.0074 14.8 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EGO25890.1 - 0.0014 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO25890.1 - 0.011 14.5 0.8 0.019 13.8 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGO25890.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 EGO25890.1 - 0.14 12.7 0.5 2.6 8.6 0.1 2.7 3 0 0 3 3 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EGO25890.1 - 0.16 11.3 1.0 0.29 10.4 0.7 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Terpene_synth PF01397.16 EGO25892.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Metallophos PF00149.23 EGO25893.1 - 6.6e-40 136.6 0.6 8.4e-40 136.3 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO25893.1 - 0.0054 16.5 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCCH PF00642.19 EGO25896.1 - 4.3e-09 35.8 2.5 9.6e-09 34.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EGO25896.1 - 4.3e-08 32.7 5.4 7e-08 32.0 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO25896.1 - 7.8e-07 29.0 10.9 1.3e-06 28.2 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25896.1 - 1.1e-06 28.2 9.3 1.8e-06 27.5 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO25896.1 - 0.00011 21.9 8.2 0.00018 21.2 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO25896.1 - 0.00017 21.1 10.6 0.00034 20.2 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO25896.1 - 0.00052 19.8 7.3 0.0012 18.7 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO25896.1 - 0.0028 17.3 6.3 0.0071 16.0 4.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RanBP PF00641.13 EGO25896.1 - 0.02 13.9 1.2 0.051 12.6 0.8 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others K167R PF08065.7 EGO25896.1 - 0.083 12.9 0.8 0.23 11.5 0.5 1.8 1 1 0 1 1 1 0 K167R (NUC007) repeat zf-rbx1 PF12678.2 EGO25896.1 - 2.4 8.3 6.7 7.8 6.6 4.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Ribosomal_60s PF00428.14 EGO25896.1 - 4.1 7.8 10.2 8.6 6.8 0.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein adh_short PF00106.20 EGO25897.1 - 7.7e-22 77.9 1.8 8.2e-22 77.8 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO25897.1 - 1.2e-07 31.7 0.1 2.1e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO25897.1 - 4e-07 29.8 0.3 9.5e-07 28.6 0.2 1.6 1 1 0 1 1 1 1 KR domain FMN_red PF03358.10 EGO25897.1 - 0.013 14.9 0.6 0.039 13.4 0.1 1.9 2 0 0 2 2 2 0 NADPH-dependent FMN reductase AdoHcyase_NAD PF00670.16 EGO25897.1 - 0.95 9.2 4.8 1.5 8.6 2.4 1.9 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Voltage_CLC PF00654.15 EGO25898.1 - 1e-90 304.3 34.4 1.4e-90 303.8 23.8 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EGO25898.1 - 6.1e-11 41.9 0.2 6.6e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain TPR_10 PF13374.1 EGO25900.1 - 9.6e-39 130.2 2.1 1.1e-10 41.1 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25900.1 - 4.8e-37 125.7 3.8 5.7e-20 71.0 0.1 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.17 EGO25900.1 - 3.1e-17 62.3 0.0 5.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EGO25900.1 - 9.4e-17 59.4 10.2 6.6e-05 22.4 0.1 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25900.1 - 2.3e-14 52.2 6.1 0.0001 21.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO25900.1 - 2.3e-14 52.7 1.9 1.5e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO25900.1 - 5.6e-12 44.5 5.4 0.0063 16.3 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25900.1 - 2.6e-09 36.5 1.0 0.95 9.8 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO25900.1 - 3.4e-09 37.1 0.6 0.00041 20.9 0.1 3.6 4 1 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25900.1 - 6.3e-08 32.5 2.6 2.5 8.9 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25900.1 - 8.2e-08 31.4 7.2 0.013 15.1 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO25900.1 - 3e-07 30.6 2.5 0.063 13.6 0.1 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat Rab5-bind PF09311.6 EGO25900.1 - 2.7e-06 27.3 0.1 0.35 10.7 0.0 3.7 2 1 2 4 4 3 2 Rabaptin-like protein Apc3 PF12895.2 EGO25900.1 - 3.2e-06 27.1 5.1 0.0012 18.9 0.2 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EGO25900.1 - 0.0025 18.0 0.0 55 4.6 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat PPR PF01535.15 EGO25900.1 - 0.004 17.0 0.7 3.1 7.9 0.0 4.2 4 0 0 4 4 4 1 PPR repeat AAA_16 PF13191.1 EGO25900.1 - 0.0041 17.1 0.1 0.02 14.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain TPR_3 PF07720.7 EGO25900.1 - 0.0048 16.6 8.1 6.4 6.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 EGO25900.1 - 0.0099 16.0 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGO25900.1 - 0.013 15.9 0.0 9.1 6.8 0.0 3.5 4 1 0 4 4 3 0 Miro-like protein ThiC-associated PF13667.1 EGO25900.1 - 0.018 14.6 1.1 14 5.3 0.0 3.3 2 1 0 3 3 3 0 ThiC-associated domain AAA_24 PF13479.1 EGO25900.1 - 0.023 14.2 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO25900.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO25900.1 - 0.027 14.1 0.1 0.12 11.9 0.0 2.3 2 1 0 2 2 2 0 NACHT domain TPR_5 PF12688.2 EGO25900.1 - 0.2 11.7 2.7 17 5.4 0.0 3.1 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_6 PF13174.1 EGO25900.1 - 0.61 10.6 6.3 26 5.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DKNYY PF13644.1 EGO25902.1 - 0.049 13.8 0.7 0.053 13.7 0.5 1.1 1 0 0 1 1 1 0 DKNYY family zf-C2H2 PF00096.21 EGO25904.1 - 0.0068 16.6 2.5 0.052 13.9 0.0 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO25904.1 - 0.11 12.8 1.7 1.3 9.5 0.0 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-CCHC PF00098.18 EGO25905.1 - 2.5e-08 33.4 2.5 5.4e-08 32.3 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO25905.1 - 9.3e-07 28.8 0.0 3.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein PIG-U PF06728.8 EGO25907.1 - 3.2e-102 342.2 33.5 3.6e-102 342.0 23.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF4489 PF14879.1 EGO25907.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) Orthopox_A5L PF06193.6 EGO25909.1 - 0.0059 16.5 0.2 0.008 16.1 0.2 1.2 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like 4HB_MCP_1 PF12729.2 EGO25909.1 - 0.0066 15.8 0.5 0.009 15.3 0.3 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF4618 PF15397.1 EGO25909.1 - 0.014 14.7 0.4 0.017 14.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Cluap1 PF10234.4 EGO25909.1 - 0.019 14.2 0.2 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 AIP3 PF03915.8 EGO25909.1 - 0.037 12.9 0.3 0.05 12.5 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Rootletin PF15035.1 EGO25909.1 - 0.039 13.9 1.1 0.056 13.4 0.8 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.1 EGO25909.1 - 0.041 13.8 0.9 0.053 13.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CASP_C PF08172.7 EGO25909.1 - 0.057 12.4 0.2 0.071 12.1 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal Spc7 PF08317.6 EGO25909.1 - 0.074 11.7 0.8 0.099 11.2 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.20 EGO25909.1 - 0.079 13.1 0.4 0.099 12.8 0.3 1.2 1 0 0 1 1 1 0 Syntaxin Peptidase_S64 PF08192.6 EGO25909.1 - 0.11 10.8 0.2 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 DivIC PF04977.10 EGO25909.1 - 0.17 11.3 1.1 0.25 10.8 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF2408 PF10303.4 EGO25909.1 - 0.17 11.9 1.7 0.31 11.1 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PDE8 PF08629.5 EGO25911.1 - 1.3e-10 40.9 9.2 0.015 15.0 0.2 4.4 1 1 3 4 4 4 4 PDE8 phosphodiesterase PspB PF06667.7 EGO25911.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B Clathrin-link PF09268.5 EGO25911.1 - 0.073 12.1 6.6 14 4.8 0.1 3.7 4 0 0 4 4 4 0 Clathrin, heavy-chain linker Pkinase PF00069.20 EGO25912.1 - 3.7e-10 39.3 0.0 9.6e-08 31.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25912.1 - 0.0039 16.2 0.0 0.035 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGO25914.1 - 1.6e-10 40.6 0.0 1.1e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25914.1 - 0.0038 16.3 0.0 0.084 11.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase 6PF2K PF01591.13 EGO25917.1 - 2.6e-58 196.7 0.2 3.4e-58 196.3 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGO25917.1 - 4e-31 108.2 0.0 7.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chitin_synth_2 PF03142.10 EGO25918.1 - 5.2e-232 770.9 0.5 7e-232 770.4 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGO25918.1 - 1.1e-120 403.8 0.0 1.6e-120 403.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 EGO25918.1 - 4.5e-19 69.1 0.0 3.8e-14 53.0 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGO25918.1 - 7.1e-17 61.7 5.6 2.5e-16 59.9 3.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EGO25918.1 - 3.1e-16 58.9 0.0 3.5e-10 39.5 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGO25918.1 - 3.3e-12 45.9 0.2 1.3e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EGO25918.1 - 3.8e-09 36.4 0.0 6e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGO25918.1 - 1.2e-05 24.6 0.0 0.00017 20.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF87 PF01935.12 EGO25918.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 ADH_N PF08240.7 EGO25920.1 - 4.1e-08 32.9 0.1 1.1e-06 28.3 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DUF1690 PF07956.6 EGO25923.1 - 7.6e-16 58.3 3.2 1.2e-15 57.7 2.2 1.3 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Use1 PF09753.4 EGO25924.1 - 1.4e-09 37.7 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apolipoprotein PF01442.13 EGO25924.1 - 0.0081 15.6 2.4 0.0081 15.6 0.3 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Snapin_Pallidin PF14712.1 EGO25924.1 - 7.1 7.0 6.8 13 6.1 1.4 2.4 2 1 0 2 2 2 0 Snapin/Pallidin Acyltransferase PF01553.16 EGO25926.1 - 4.1e-20 71.5 0.0 7.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase GST_N_3 PF13417.1 EGO25928.1 - 1.7e-12 47.3 0.0 4.6e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO25928.1 - 1.1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO25928.1 - 5.6e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO25928.1 - 9.6e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO25928.1 - 0.00031 20.5 0.0 0.00062 19.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO25928.1 - 0.0074 16.7 0.1 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DASH_Dad4 PF08650.5 EGO25929.1 - 4.3e-17 61.7 1.3 4.6e-17 61.6 0.9 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Pro_dh PF01619.13 EGO25929.1 - 0.096 11.6 0.3 0.092 11.7 0.2 1.0 1 0 0 1 1 1 0 Proline dehydrogenase Glyco_tranf_2_3 PF13641.1 EGO25931.1 - 5.5e-23 81.9 0.0 7.8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO25931.1 - 1.7e-08 34.3 0.0 2.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGO25931.1 - 2.5e-07 30.1 0.0 7.8e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EGO25931.1 - 3.6e-05 23.5 5.3 6.8e-05 22.6 3.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 EGO25931.1 - 0.035 12.5 1.0 0.18 10.1 0.7 1.9 1 1 0 1 1 1 0 Chitin synthase IBR PF01485.16 EGO25932.1 - 9e-15 54.3 39.0 1.1e-09 38.0 11.4 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EGO25932.1 - 1.1e-05 25.3 5.4 1.1e-05 25.3 3.7 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO25932.1 - 6.4e-05 22.6 5.9 6.4e-05 22.6 4.1 3.7 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EGO25932.1 - 0.00011 21.8 3.2 0.00011 21.8 2.3 4.2 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO25932.1 - 0.0006 19.4 4.0 0.0006 19.4 2.8 4.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO25932.1 - 0.0079 15.8 5.7 0.0079 15.8 3.9 3.6 3 0 0 3 3 3 1 zinc-RING finger domain tRNA-synt_2 PF00152.15 EGO25933.1 - 1.3e-88 297.0 0.0 1.8e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO25933.1 - 9.5e-12 44.6 0.1 1.3e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGO25933.1 - 6.1e-09 35.4 0.0 4.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGO25933.1 - 0.011 15.2 0.0 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) HSP70 PF00012.15 EGO25934.1 - 9.7e-160 532.3 0.3 3.4e-159 530.5 0.0 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGO25934.1 - 8e-13 47.6 0.1 2.7e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein PC-Esterase PF13839.1 EGO25937.1 - 7.4e-08 32.5 0.0 3.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Retrotrans_gag PF03732.12 EGO25942.1 - 0.00081 19.4 0.3 0.0024 17.9 0.2 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_3 PF14244.1 EGO25942.1 - 0.1 12.1 1.1 0.41 10.1 0.8 1.9 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type IF2_N PF04760.10 EGO25943.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Mito_carr PF00153.22 EGO25945.1 - 1.3e-63 210.7 4.2 1e-21 76.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 EGO25947.1 - 1.3e-08 34.6 4.0 0.0029 17.8 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO25947.1 - 3.3e-06 27.1 0.6 0.054 13.8 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO25947.1 - 7.4e-05 22.8 4.5 0.21 12.0 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGO25947.1 - 0.0068 16.5 2.1 0.93 9.7 0.0 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO25947.1 - 0.054 13.6 4.1 3.4 7.9 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SprT-like PF10263.4 EGO25947.1 - 0.06 12.9 0.5 0.095 12.3 0.3 1.3 1 0 0 1 1 1 0 SprT-like family Nucleoplasmin PF03066.10 EGO25947.1 - 0.21 11.0 4.8 0.16 11.4 1.8 1.8 2 0 0 2 2 2 0 Nucleoplasmin Zn_Tnp_IS1595 PF12760.2 EGO25947.1 - 0.62 9.9 4.0 1.5 8.6 2.7 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EGO25947.1 - 1 9.1 4.0 1.5 8.6 1.4 2.0 1 1 1 2 2 2 0 BED zinc finger NUDIX PF00293.23 EGO25949.1 - 2.1e-16 59.7 0.0 3.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EGO25949.1 - 6.2e-14 52.1 0.0 1.6e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EGO25949.1 - 0.0051 16.2 0.2 0.0095 15.4 0.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PepSY_2 PF13670.1 EGO25949.1 - 0.47 10.4 2.1 20 5.1 1.1 3.0 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Glyco_hydro_18 PF00704.23 EGO25950.1 - 1.6e-59 202.1 0.9 2.5e-59 201.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CoA_binding_2 PF13380.1 EGO25951.1 - 5.8e-27 94.1 0.0 6.6e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EGO25951.1 - 0.035 14.6 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain PALP PF00291.20 EGO25952.1 - 4.9e-53 180.3 0.1 1.7e-52 178.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.20 EGO25956.1 - 6.5e-48 163.5 0.0 7.5e-47 160.0 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CbiG_N PF11760.3 EGO25956.1 - 0.054 13.1 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal SWIRM PF04433.12 EGO25957.1 - 5.2e-16 58.5 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EGO25957.1 - 7.7e-10 38.6 0.1 1.7e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO25957.1 - 0.0016 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EGO25957.1 - 0.45 10.0 7.6 1.1 8.8 5.3 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type TPR_11 PF13414.1 EGO25959.1 - 1.1e-30 105.0 44.8 3.7e-06 26.5 0.0 11.5 12 2 2 14 14 13 10 TPR repeat TPR_19 PF14559.1 EGO25959.1 - 2.2e-27 95.2 38.3 8.3e-06 26.0 0.0 11.3 9 2 3 12 12 11 8 Tetratricopeptide repeat TPR_12 PF13424.1 EGO25959.1 - 6.3e-25 86.9 34.9 1.2e-06 28.3 0.4 10.1 8 2 2 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGO25959.1 - 2.1e-21 74.0 49.2 0.017 15.0 0.0 15.1 17 0 0 17 17 16 8 Tetratricopeptide repeat TPR_1 PF00515.23 EGO25959.1 - 2.4e-21 74.3 30.3 0.00084 18.8 0.0 11.8 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGO25959.1 - 2.6e-16 58.6 53.1 0.0011 19.4 0.1 14.9 14 5 6 20 20 15 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGO25959.1 - 2.3e-13 50.4 59.3 3.6e-05 24.2 0.1 11.7 12 1 0 12 12 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO25959.1 - 2.6e-12 45.5 20.5 0.09 12.5 0.0 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO25959.1 - 1.4e-10 40.9 34.5 0.0014 18.9 0.0 12.4 15 0 0 15 15 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO25959.1 - 1.9e-09 36.6 27.1 0.028 14.1 0.1 10.4 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO25959.1 - 4.6e-09 35.7 18.1 3.1 8.2 0.0 9.8 9 0 0 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO25959.1 - 1.6e-08 34.5 22.8 0.032 14.3 1.2 7.0 6 2 2 8 8 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EGO25959.1 - 3.7e-05 23.5 36.5 0.0065 16.3 0.3 9.7 10 0 0 10 10 9 2 Tetratricopeptide repeat DUF2989 PF11207.3 EGO25959.1 - 0.0003 20.3 2.9 0.19 11.1 0.0 4.7 4 1 0 4 4 4 1 Protein of unknown function (DUF2989) TPR_4 PF07721.9 EGO25959.1 - 0.037 14.4 0.0 0.037 14.4 0.0 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat Peptidase_C12 PF01088.16 EGO25960.1 - 4.7e-44 150.1 0.0 7.1e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Chromo PF00385.19 EGO25961.1 - 5.7e-08 32.3 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Viral_helicase1 PF01443.13 EGO25962.1 - 0.13 11.7 0.8 1.4 8.3 0.0 2.4 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2938 PF11158.3 EGO25963.1 - 0.015 14.6 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) Retrotrans_gag PF03732.12 EGO25964.1 - 7.6e-06 25.9 1.6 9.7e-06 25.5 0.2 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein UbiA PF01040.13 EGO25966.1 - 2e-16 59.9 12.1 2.6e-16 59.6 8.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RNase_T PF00929.19 EGO25969.1 - 3.4e-18 66.4 0.0 4.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Asp PF00026.18 EGO25970.1 - 1.3e-61 208.6 7.2 1.6e-61 208.3 5.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO25970.1 - 1.2e-09 38.3 0.5 1.2e-09 38.3 0.3 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Acyl-CoA_dh_C PF12806.2 EGO25970.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Fungal_trans PF04082.13 EGO25971.1 - 1.7e-09 36.9 0.0 2.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO25971.1 - 7.1e-06 25.8 16.2 7.1e-06 25.8 11.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.15 EGO25973.1 - 1.6e-77 260.8 0.0 2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO25973.1 - 0.0002 20.6 1.2 0.0004 19.6 0.3 1.8 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO25973.1 - 0.00067 18.8 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FUSC_2 PF13515.1 EGO25974.1 - 1.3e-14 54.2 4.5 1.3e-14 54.2 3.1 2.9 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EGO25974.1 - 2.9e-09 36.8 0.1 4.2e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EGO25974.1 - 1.4e-06 27.2 5.9 0.00081 18.1 1.3 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 EGO25974.1 - 1.3e-05 23.8 19.4 0.0021 16.6 1.9 3.6 3 1 0 3 3 3 3 Fusaric acid resistance protein family DUF2787 PF10980.3 EGO25974.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) AAA_13 PF13166.1 EGO25974.1 - 0.28 9.5 0.1 0.42 9.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain API5 PF05918.6 EGO25975.1 - 8.8e-17 60.8 0.0 8.8e-17 60.8 0.0 1.6 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 EGO25975.1 - 0.0023 18.1 0.2 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats DUF1963 PF09234.5 EGO25975.1 - 0.12 12.6 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Cytochrom_B561 PF03188.11 EGO25976.1 - 1.4e-10 41.1 5.7 2.2e-10 40.5 4.0 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EGO25976.1 - 0.01 15.3 3.0 0.01 15.3 2.1 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF2427) DUF998 PF06197.8 EGO25976.1 - 0.062 12.6 15.7 1.3 8.3 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) O-ag_pol_Wzy PF14296.1 EGO25976.1 - 0.069 11.7 0.5 0.084 11.4 0.0 1.3 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF2243 PF10002.4 EGO25976.1 - 0.2 11.4 4.8 0.11 12.3 1.8 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) S-methyl_trans PF02574.11 EGO25977.1 - 1.7e-31 109.7 0.0 3.1e-15 56.2 0.0 3.1 3 0 0 3 3 3 3 Homocysteine S-methyltransferase Pkinase PF00069.20 EGO25978.1 - 1.3e-68 231.0 0.0 1.7e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO25978.1 - 1.9e-37 128.7 0.0 3e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGO25978.1 - 9e-17 60.9 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EGO25978.1 - 7.6e-07 28.4 0.2 3.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO25978.1 - 4.1e-06 25.9 0.0 6.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO25978.1 - 0.00048 19.9 0.0 0.044 13.4 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO25978.1 - 0.0084 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Zn_clus PF00172.13 EGO25979.1 - 8.5e-05 22.3 8.7 0.00011 22.0 4.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPC22 PF04573.7 EGO25981.1 - 3.1e-38 130.7 0.1 3.5e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Acyltransferase PF01553.16 EGO25982.1 - 3.3e-16 58.9 0.0 5.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CobD_Cbib PF03186.8 EGO25982.1 - 0.034 13.2 1.1 0.053 12.5 0.8 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Ribonuc_red_lgC PF02867.10 EGO25982.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Lipase_3 PF01764.20 EGO25983.1 - 2.3e-30 105.0 0.0 3.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EGO25983.1 - 0.042 13.2 0.1 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.15 EGO25983.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Hpt PF01627.18 EGO25983.1 - 0.19 11.7 0.0 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Hpt domain Ribosomal_S2 PF00318.15 EGO25984.1 - 2.6e-47 160.7 0.1 8.6e-24 83.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Menin PF05053.8 EGO25985.1 - 0.31 9.1 7.8 0.45 8.6 5.4 1.1 1 0 0 1 1 1 0 Menin Methyltransf_22 PF13383.1 EGO25988.1 - 7.8e-26 91.0 0.0 9.2e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EGO25988.1 - 1.6e-06 28.1 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF1892 PF08987.5 EGO25988.1 - 0.03 14.3 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) Glyoxalase PF00903.20 EGO25989.1 - 4.7e-24 84.7 0.0 5.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGO25989.1 - 6.5e-16 58.8 0.0 8.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGO25989.1 - 5.4e-08 32.8 0.0 2e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EGO25989.1 - 0.04 13.5 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Glyoxalase_3 PF13468.1 EGO25989.1 - 0.05 13.5 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Nefa_Nip30_N PF10187.4 EGO25990.1 - 6.7e-24 84.0 11.1 6.7e-24 84.0 7.7 1.8 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 EGO25990.1 - 0.038 13.2 18.8 0.046 12.9 13.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCPVI PF02993.9 EGO25990.1 - 1.4 9.0 11.3 1.2 9.2 6.6 1.7 2 0 0 2 2 2 0 Minor capsid protein VI Glyco_hydro_2 PF00703.16 EGO25991.1 - 0.0027 18.1 0.0 0.0069 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 LRR_4 PF12799.2 EGO25992.1 - 1e-47 159.0 76.3 4.5e-10 38.9 1.8 13.3 4 2 12 16 16 16 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO25992.1 - 1.7e-44 149.3 58.1 2.8e-14 52.6 3.9 9.3 5 3 5 11 11 11 10 Leucine rich repeat PP2C PF00481.16 EGO25992.1 - 8.6e-40 136.7 0.0 1.5e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EGO25992.1 - 2.7e-24 81.4 70.6 0.0062 16.3 0.2 19.3 20 0 0 20 20 20 9 Leucine Rich Repeat Guanylate_cyc PF00211.15 EGO25992.1 - 2.6e-21 75.8 0.0 4.7e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EGO25992.1 - 9.2e-16 55.2 49.8 0.25 11.6 0.0 18.3 18 0 0 18 18 18 2 Leucine rich repeat LRR_6 PF13516.1 EGO25992.1 - 4e-07 29.4 53.8 5.2 7.4 0.3 16.6 15 2 2 17 17 17 2 Leucine Rich repeat Ad_cyc_g-alpha PF08509.6 EGO25992.1 - 5.1e-06 25.7 0.0 2.1e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.1 EGO25992.1 - 0.00022 20.8 19.2 0.012 15.1 0.3 4.9 2 1 2 4 4 4 3 Leucine-rich repeat Mg_trans_NIPA PF05653.9 EGO25993.1 - 1.2e-82 277.2 26.9 1.7e-82 276.7 18.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EGO25993.1 - 6e-08 32.7 9.5 6e-08 32.7 6.6 3.9 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EGO25993.1 - 5.4e-06 26.5 9.3 5.4e-06 26.5 6.4 3.4 2 2 1 3 3 3 1 Multidrug resistance efflux transporter YABBY PF04690.8 EGO25993.1 - 0.049 13.8 0.1 0.087 13.0 0.1 1.3 1 0 0 1 1 1 0 YABBY protein DUF3192 PF11399.3 EGO25996.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) G-alpha PF00503.15 EGO25997.1 - 5.1e-119 397.4 0.0 6.1e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO25997.1 - 9.5e-12 44.4 0.4 1.6e-07 30.7 0.0 2.9 2 1 1 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO25997.1 - 0.021 13.9 0.3 1.3 8.1 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EGO25997.1 - 0.08 12.8 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO25997.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NOG1 PF06858.9 EGO25998.1 - 1.5e-27 95.2 0.0 3.4e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EGO25998.1 - 3.1e-26 90.8 1.6 5.4e-26 90.0 0.5 2.0 1 1 1 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EGO25998.1 - 1.7e-16 60.1 0.0 5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO25998.1 - 1.2e-10 40.8 0.0 3e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGO25998.1 - 0.0047 17.4 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EGO25998.1 - 0.005 16.0 0.0 0.047 12.8 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGO25998.1 - 0.0083 15.2 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EGO25998.1 - 0.039 13.7 1.4 2.7 7.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family MobB PF03205.9 EGO25998.1 - 0.04 13.6 0.0 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_M24 PF00557.19 EGO25999.1 - 5.6e-41 140.4 0.0 7.7e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGO25999.1 - 1.4e-17 64.4 0.0 1.2e-15 58.1 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.19 EGO26001.1 - 2.9e-83 279.9 27.5 3.3e-83 279.7 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO26001.1 - 2.8e-26 92.0 26.4 2.8e-26 92.0 18.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGO26001.1 - 0.0018 16.7 28.3 0.0038 15.6 3.8 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein ATP-synt_8 PF00895.15 EGO26001.1 - 3.2 8.0 7.3 0.33 11.2 0.9 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 Sugar_tr PF00083.19 EGO26002.1 - 1.9e-69 234.4 23.5 2.4e-69 234.0 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO26002.1 - 1.3e-23 83.2 49.4 5.8e-19 68.0 17.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CCSMST1 PF15013.1 EGO26002.1 - 1.4 8.8 4.3 12 5.8 1.9 2.5 2 0 0 2 2 2 0 CCSMST1 family Pyridoxal_deC PF00282.14 EGO26004.1 - 1.1e-06 27.4 0.0 6.1e-05 21.6 0.0 2.8 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain gag-asp_proteas PF13975.1 EGO26006.1 - 8.4e-09 35.1 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO26006.1 - 1.9e-07 31.1 0.0 2.1e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO26006.1 - 3.1e-05 24.3 0.0 4.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EGO26007.1 - 0.00083 19.1 4.2 0.0016 18.2 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26007.1 - 0.0044 17.0 0.1 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-PHD-like PF15446.1 EGO26007.1 - 0.019 14.2 2.1 0.046 13.0 1.5 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain HTH_20 PF12840.2 EGO26008.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain V-ATPase_C PF03223.10 EGO26009.1 - 3.1e-106 355.4 0.7 3.8e-106 355.1 0.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GATase_5 PF13507.1 EGO26010.1 - 5.5e-98 327.0 0.0 8.1e-98 326.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGO26010.1 - 3.4e-48 163.5 0.1 1e-26 93.7 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGO26010.1 - 1.6e-23 82.7 1.7 3.1e-23 81.8 0.0 2.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain PX PF00787.19 EGO26011.1 - 2.9e-25 88.2 0.0 4.4e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 PX domain Trs65 PF12735.2 EGO26012.1 - 7.7e-23 81.2 5.2 2.1e-22 79.8 0.0 3.5 4 1 0 4 4 4 1 TRAPP trafficking subunit Trs65 SDH_beta PF03315.10 EGO26012.1 - 0.044 13.8 0.2 0.093 12.7 0.2 1.4 1 0 0 1 1 1 0 Serine dehydratase beta chain Glyco_hydro_cc PF11790.3 EGO26014.1 - 4.9e-61 206.1 2.4 5.6e-61 206.0 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Tetraspannin PF00335.15 EGO26015.1 - 0.0032 16.7 3.5 0.0055 16.0 2.4 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2749 PF10907.3 EGO26015.1 - 0.021 14.6 0.1 0.077 12.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) BCS1_N PF08740.6 EGO26017.1 - 2e-25 89.5 0.5 4.5e-25 88.3 0.4 1.7 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGO26017.1 - 1.1e-14 54.7 0.0 6.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EGO26017.1 - 0.00021 20.7 0.2 0.016 14.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO26017.1 - 0.00043 20.3 0.0 0.00043 20.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EGO26017.1 - 0.00094 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGO26017.1 - 0.0014 19.4 0.7 0.03 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGO26017.1 - 0.014 14.9 0.1 0.014 14.9 0.0 2.4 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EGO26017.1 - 0.032 13.8 2.7 5 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGO26017.1 - 0.042 14.1 0.8 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EGO26017.1 - 0.046 13.4 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EGO26017.1 - 0.049 13.4 0.0 0.049 13.4 0.0 2.3 2 1 0 3 3 3 0 AAA domain DUF4262 PF14081.1 EGO26017.1 - 0.1 12.6 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) DDRGK PF09756.4 EGO26017.1 - 0.13 11.6 19.4 24 4.2 15.4 2.4 2 0 0 2 2 2 0 DDRGK domain AAA_23 PF13476.1 EGO26017.1 - 0.42 10.9 17.4 19 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 EGO26022.1 - 3.9e-128 427.4 0.1 4.7e-128 427.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO26022.1 - 1.3e-16 60.3 1.1 9.3e-12 44.5 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO26022.1 - 9.6e-05 21.6 0.6 0.0088 15.2 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO26022.1 - 0.0002 21.8 0.4 0.18 12.3 0.0 2.8 3 1 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 EGO26022.1 - 0.014 15.3 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO26022.1 - 0.022 14.2 0.0 4.7 6.6 0.0 2.8 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGO26022.1 - 0.025 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.15 EGO26022.1 - 0.029 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 EGO26022.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Cyt-b5 PF00173.23 EGO26023.1 - 5.5e-11 42.1 0.0 6.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Methyltransf_21 PF05050.7 EGO26024.1 - 0.024 14.5 0.2 0.06 13.2 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase FkbM domain AAA_17 PF13207.1 EGO26028.1 - 1.1e-16 61.7 0.0 1.3e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO26028.1 - 0.0012 18.2 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGO26028.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EGO26028.1 - 0.0024 17.7 0.0 0.0058 16.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 EGO26028.1 - 0.0035 17.2 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGO26028.1 - 0.0035 16.2 0.0 0.0051 15.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 EGO26028.1 - 0.0055 17.0 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EGO26028.1 - 0.0084 16.0 0.0 0.049 13.5 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 EGO26028.1 - 0.0094 16.2 0.4 0.017 15.4 0.3 1.3 1 0 0 1 1 1 1 ABC transporter MobB PF03205.9 EGO26028.1 - 0.011 15.4 0.1 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGO26028.1 - 0.11 12.5 0.3 0.21 11.5 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 EGO26028.1 - 0.14 12.6 0.2 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Miro-like protein FLYWCH PF04500.11 EGO26029.1 - 3.6 7.5 5.6 2.8 7.9 0.5 2.2 2 0 0 2 2 2 0 FLYWCH zinc finger domain MMtag PF10159.4 EGO26030.1 - 1.2e-31 108.5 3.8 1.2e-31 108.5 2.6 3.1 2 1 0 3 3 3 1 Kinase phosphorylation protein Ank_2 PF12796.2 EGO26032.1 - 5.4e-18 65.1 0.0 5e-09 36.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO26032.1 - 2.5e-16 58.5 0.0 7.4e-06 25.5 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGO26032.1 - 9.5e-16 57.4 0.0 4e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO26032.1 - 1.4e-14 54.1 0.1 2e-05 24.9 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO26032.1 - 1.6e-09 37.0 0.0 0.0037 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EGO26033.1 - 3.3e-22 78.6 0.5 2e-15 56.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO26033.1 - 6.9e-17 60.3 1.6 8.8e-07 28.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGO26033.1 - 7.5e-17 61.3 0.1 3.3e-11 43.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO26033.1 - 4.7e-16 58.4 0.2 1.1e-11 44.5 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO26033.1 - 1.1e-10 40.6 0.3 0.00022 21.1 0.0 3.0 4 0 0 4 4 4 2 Ankyrin repeat adh_short PF00106.20 EGO26034.1 - 1.3e-10 41.4 0.0 2.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO26034.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 KR domain ECH PF00378.15 EGO26035.1 - 2.4e-38 131.6 0.0 3.4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGO26035.1 - 0.0053 16.8 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region zf-CCHC PF00098.18 EGO26036.1 - 5.9e-08 32.2 29.4 0.00039 20.2 0.8 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.1 EGO26036.1 - 0.00017 20.9 1.5 0.015 14.7 0.1 3.8 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.1 EGO26036.1 - 0.049 13.3 24.6 0.33 10.6 0.4 4.6 4 0 0 4 4 4 0 Zinc knuckle Yippee-Mis18 PF03226.9 EGO26037.1 - 1.4e-17 63.4 0.1 1.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PhnA_Zn_Ribbon PF08274.7 EGO26037.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon adh_short PF00106.20 EGO26039.1 - 6.6e-25 87.9 0.0 9e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO26039.1 - 3.9e-23 82.4 0.0 4.5e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO26039.1 - 6.1e-12 45.5 0.0 8.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 KR domain IlvN PF07991.7 EGO26040.1 - 8.4e-47 158.6 0.0 1.2e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EGO26040.1 - 6e-08 33.0 0.3 1.4e-07 31.8 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGO26040.1 - 2.6e-06 26.6 0.0 4.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvC PF01450.14 EGO26040.1 - 5.1e-06 26.4 0.1 8.9e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EGO26040.1 - 0.00022 21.1 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGO26040.1 - 0.00028 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGO26040.1 - 0.035 13.8 0.1 0.25 11.0 0.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3991 PF13154.1 EGO26040.1 - 0.083 13.0 0.1 9.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Vps53_N PF04100.7 EGO26041.1 - 4.9e-88 295.4 2.1 4.9e-88 295.4 1.4 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGO26041.1 - 1.1e-07 31.1 6.1 1.1e-07 31.1 4.3 2.3 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EGO26041.1 - 0.0015 18.2 3.6 0.0015 18.2 2.5 2.2 2 1 0 2 2 2 1 Exocyst complex component Sec5 DUF1978 PF09321.5 EGO26041.1 - 0.058 12.8 6.1 0.015 14.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Mob_Pre PF01076.14 EGO26041.1 - 0.15 11.6 3.9 0.42 10.2 0.6 2.2 2 0 0 2 2 2 0 Plasmid recombination enzyme TSC22 PF01166.13 EGO26041.1 - 3.1 7.8 7.0 1.2 9.1 1.0 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF1664 PF07889.7 EGO26041.1 - 3.8 7.3 12.9 0.48 10.2 3.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF947 PF06102.7 EGO26041.1 - 7.5 6.3 7.6 1.2 8.9 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF947) gag_pre-integrs PF13976.1 EGO26042.1 - 5e-10 38.8 0.3 7.8e-10 38.2 0.2 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.12 EGO26043.1 - 0.0069 16.4 4.2 0.026 14.5 1.2 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EGO26044.1 - 3.3e-06 26.6 0.0 5.7e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO26044.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Myb_DNA-bind_4 PF13837.1 EGO26045.1 - 0.0014 18.7 0.0 0.029 14.5 0.0 2.8 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Pterin_4a PF01329.14 EGO26046.1 - 3.2e-11 42.8 0.1 5.7e-11 42.0 0.1 1.4 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Mei4 PF13971.1 EGO26046.1 - 0.028 13.4 0.2 0.04 12.8 0.1 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Beta_elim_lyase PF01212.16 EGO26047.1 - 2.1e-60 204.3 0.0 5.5e-60 202.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGO26047.1 - 0.015 14.2 0.0 0.032 13.1 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGO26047.1 - 0.035 12.3 0.0 0.065 11.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Urb2 PF10441.4 EGO26048.1 - 1.5e-35 122.8 2.2 5.2e-34 117.7 0.0 3.5 3 1 0 3 3 3 1 Urb2/Npa2 family Aldo_ket_red PF00248.16 EGO26050.1 - 8e-33 113.4 0.0 1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PEX11 PF05648.9 EGO26051.1 - 1.8e-52 177.7 0.6 2.1e-52 177.6 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) UreF PF01730.11 EGO26051.1 - 0.11 12.5 1.2 0.65 10.1 0.1 2.1 1 1 1 2 2 2 0 UreF DnaJ PF00226.26 EGO26053.1 - 1.2e-20 72.9 0.3 2.7e-20 71.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain AICARFT_IMPCHas PF01808.13 EGO26053.1 - 0.023 13.8 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme DUF4407 PF14362.1 EGO26053.1 - 0.36 9.7 5.8 0.4 9.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2681 PF10883.3 EGO26053.1 - 2.1 8.5 10.7 0.16 12.2 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) IncA PF04156.9 EGO26053.1 - 4.1 6.9 6.1 4.8 6.7 4.2 1.2 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 EGO26053.1 - 5 5.2 8.9 4.9 5.2 6.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein GMC_oxred_N PF00732.14 EGO26056.1 - 6.1e-66 222.5 0.0 8.2e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO26056.1 - 1.4e-30 106.4 0.0 2.5e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EGO26056.1 - 0.0045 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EGO26056.1 - 0.024 13.5 0.0 1.7 7.4 0.0 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase CMAS PF02353.15 EGO26057.1 - 2.5e-51 174.3 0.1 4.9e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EGO26057.1 - 1.1e-09 38.9 0.1 1e-08 35.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO26057.1 - 7.1e-09 35.5 0.1 1.9e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO26057.1 - 8.3e-05 22.5 0.1 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO26057.1 - 0.00039 20.8 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO26057.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGO26057.1 - 0.012 15.2 0.0 0.039 13.5 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO26057.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EGO26057.1 - 0.078 12.5 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 E1-E2_ATPase PF00122.15 EGO26058.1 - 8.2e-27 93.7 0.0 2.2e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGO26058.1 - 2.1e-24 86.7 0.0 4e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO26058.1 - 6e-22 79.1 0.0 1.3e-20 74.6 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EGO26058.1 - 7.3e-19 67.7 0.8 4.1e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 EGO26058.1 - 2.8e-05 23.9 0.0 6.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGO26058.1 - 0.00071 18.9 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO26058.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TPR_10 PF13374.1 EGO26059.1 - 1.2e-126 409.6 26.6 1.8e-11 43.5 0.0 11.4 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.1 EGO26059.1 - 2.4e-121 395.8 29.7 4e-19 68.3 0.1 6.7 3 1 4 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26059.1 - 3.6e-44 146.6 32.2 0.00072 19.0 0.1 11.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26059.1 - 1.5e-43 143.1 21.3 0.00027 20.5 0.0 11.2 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26059.1 - 1.2e-34 115.3 25.6 0.0097 15.7 0.1 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 EGO26059.1 - 1.2e-32 111.3 20.5 1.5e-06 27.7 0.2 6.6 2 1 5 8 8 8 8 TPR repeat TPR_16 PF13432.1 EGO26059.1 - 8.6e-29 99.5 15.5 4.7e-06 27.1 0.0 6.4 6 1 0 6 6 5 5 Tetratricopeptide repeat Apc3 PF12895.2 EGO26059.1 - 5.6e-24 84.0 12.5 1.8e-08 34.3 0.6 6.1 1 1 5 7 7 7 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGO26059.1 - 2.7e-23 82.0 17.2 0.00056 20.1 0.1 8.4 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 EGO26059.1 - 7e-21 72.8 18.6 1.3 9.8 0.1 11.8 8 2 3 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO26059.1 - 4.8e-18 63.5 32.0 0.83 9.5 0.1 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat PPR PF01535.15 EGO26059.1 - 2.5e-17 61.5 15.3 0.071 13.1 0.1 11.2 12 0 0 12 12 12 3 PPR repeat TPR_3 PF07720.7 EGO26059.1 - 3.6e-17 61.7 38.6 0.025 14.3 0.0 10.9 10 1 0 10 10 10 7 Tetratricopeptide repeat NB-ARC PF00931.17 EGO26059.1 - 5.7e-16 58.2 0.1 9e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 EGO26059.1 - 2e-14 52.4 21.8 0.27 11.5 0.3 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_4 PF07721.9 EGO26059.1 - 2.8e-14 52.0 0.0 2.8 8.6 0.0 9.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO26059.1 - 6.2e-14 51.4 31.5 2.1 8.9 0.1 11.2 11 0 0 11 11 11 2 Tetratricopeptide repeat PPR_2 PF13041.1 EGO26059.1 - 5.6e-07 29.4 10.9 0.55 10.2 0.0 8.7 11 0 0 11 11 8 2 PPR repeat family BAG PF02179.11 EGO26059.1 - 2.9e-05 24.1 0.0 9.5e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 BAG domain Pep3_Vps18 PF05131.9 EGO26059.1 - 4.9e-05 22.7 0.9 52 3.2 0.0 7.4 9 0 0 9 9 9 0 Pep3/Vps18/deep orange family TPR_20 PF14561.1 EGO26059.1 - 0.00013 22.0 7.1 6 7.0 0.0 7.8 7 2 1 9 9 7 0 Tetratricopeptide repeat Tcf25 PF04910.9 EGO26059.1 - 0.00014 20.9 4.4 0.3 9.9 0.2 4.9 2 2 3 6 6 6 1 Transcriptional repressor TCF25 Tom22 PF04281.8 EGO26059.1 - 0.00023 20.7 0.0 44 3.5 0.0 6.3 2 2 3 7 7 7 0 Mitochondrial import receptor subunit Tom22 ubiquitin PF00240.18 EGO26059.1 - 0.00024 20.4 0.0 0.00055 19.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family AAA_16 PF13191.1 EGO26059.1 - 0.00032 20.7 0.0 0.00077 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PPR_3 PF13812.1 EGO26059.1 - 0.00043 20.3 11.0 14 6.2 0.2 7.3 7 0 0 7 7 6 0 Pentatricopeptide repeat domain AAA_22 PF13401.1 EGO26059.1 - 0.0025 17.9 0.0 0.013 15.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain PPR_1 PF12854.2 EGO26059.1 - 0.011 15.1 4.3 2.9 7.4 0.7 4.8 5 0 0 5 5 4 0 PPR repeat RuvB_N PF05496.7 EGO26059.1 - 0.016 14.2 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF4074 PF13293.1 EGO26059.1 - 0.028 14.6 1.5 36 4.6 0.0 5.2 6 0 0 6 6 3 0 Domain of unknown function (DUF4074) Arch_ATPase PF01637.13 EGO26059.1 - 0.22 11.1 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Glyco_hydro_16 PF00722.16 EGO26060.1 - 4.3e-06 26.1 0.0 7.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 COesterase PF00135.23 EGO26061.1 - 2.4e-78 264.1 0.0 3.4e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO26061.1 - 1e-08 35.0 0.1 3.4e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO26061.1 - 0.006 15.8 0.1 0.013 14.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S24 PF00717.18 EGO26062.1 - 8.2e-09 34.9 0.1 1.5e-08 34.1 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGO26062.1 - 0.01 15.3 0.0 1.1 8.7 0.0 2.4 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 His_Phos_2 PF00328.17 EGO26063.1 - 2.5e-05 23.7 0.0 0.00078 18.8 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4160 PF13711.1 EGO26063.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) SRP72 PF08492.7 EGO26064.1 - 2.6e-09 37.2 0.2 2.6e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EGO26064.1 - 7.6e-07 29.1 2.7 0.00027 21.0 1.5 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGO26064.1 - 5.7e-06 26.8 0.1 0.21 12.3 0.9 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26064.1 - 1.6e-05 24.4 1.2 0.3 11.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGO26064.1 - 0.00012 21.2 1.8 0.042 12.8 0.1 2.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO26064.1 - 0.00048 20.3 1.2 0.24 11.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO26064.1 - 0.00058 19.6 1.1 0.41 10.5 0.0 3.4 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 EGO26064.1 - 0.00074 19.1 5.0 1.5 8.5 0.6 3.4 3 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 EGO26064.1 - 0.0036 17.8 2.3 3.1 8.6 0.0 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26064.1 - 0.014 14.9 0.1 4.2 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO26064.1 - 0.02 15.3 0.3 18 6.0 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26064.1 - 0.025 14.3 0.5 2.5 8.1 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.4 EGO26064.1 - 0.031 13.7 0.7 0.045 13.2 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Alkyl_sulf_dimr PF14863.1 EGO26064.1 - 0.068 13.4 0.1 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_12 PF13424.1 EGO26064.1 - 0.098 12.6 3.9 0.38 10.7 0.3 2.5 2 1 1 3 3 2 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.8 EGO26065.1 - 3.4e-10 39.6 11.2 3.4e-10 39.6 7.7 3.5 2 1 2 4 4 4 2 pinin/SDK/memA/ protein conserved region ORC5_C PF14630.1 EGO26065.1 - 0.21 10.9 7.4 0.11 11.9 1.6 2.0 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Cellulase PF00150.13 EGO26066.1 - 1e-05 24.9 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TEA PF01285.13 EGO26067.1 - 1e-07 31.5 0.0 1.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain family RNF111_N PF15303.1 EGO26067.1 - 5.6 6.4 7.7 0.076 12.5 0.3 1.5 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Dynamin_N PF00350.18 EGO26069.1 - 4.5e-23 81.8 0.0 1.2e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGO26069.1 - 9.4e-09 35.0 0.2 1.3e-06 28.2 0.1 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_M PF01031.15 EGO26069.1 - 3.4e-06 26.0 0.1 0.006 15.4 0.1 2.7 2 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EGO26069.1 - 0.0075 16.2 0.0 0.08 12.9 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO26069.1 - 0.05 13.1 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EGO26069.1 - 0.07 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EGO26069.1 - 0.092 13.0 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EGO26069.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF960 PF06124.6 EGO26070.1 - 0.034 14.3 0.3 0.41 10.9 0.0 2.6 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) WH1 PF00568.18 EGO26070.1 - 0.053 13.2 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 WH1 domain PepSY_TM_1 PF13172.1 EGO26071.1 - 5 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix YL1 PF05764.8 EGO26073.1 - 0.0055 16.3 13.4 0.0093 15.5 9.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein PaO PF08417.7 EGO26073.1 - 0.028 14.3 1.5 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Pheophorbide a oxygenase SR-25 PF10500.4 EGO26073.1 - 0.033 13.6 10.8 0.057 12.8 7.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Prp19_bind PF06991.6 EGO26073.1 - 0.36 10.0 11.0 0.79 8.9 7.6 1.5 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain CDC45 PF02724.9 EGO26073.1 - 0.52 8.2 11.6 0.74 7.7 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 EGO26073.1 - 0.8 9.3 17.6 1.2 8.7 11.9 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 EGO26073.1 - 1.1 8.2 18.1 1.7 7.6 12.5 1.2 1 0 0 1 1 1 0 BUD22 DUF106 PF01956.11 EGO26073.1 - 3.9 6.9 5.5 3 7.3 1.6 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF106 Nop14 PF04147.7 EGO26073.1 - 8.1 4.2 18.3 1.2 7.0 10.1 1.4 2 0 0 2 2 2 0 Nop14-like family Dynamin_N PF00350.18 EGO26074.1 - 2.3e-28 99.0 0.0 4.5e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO26074.1 - 1.3e-19 70.1 0.0 2.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EGO26074.1 - 2.8e-11 43.1 0.1 1.3e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO26074.1 - 0.00057 19.8 0.0 0.0084 16.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO26074.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO26074.1 - 0.084 12.8 0.1 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EGO26074.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EGO26074.1 - 0.11 12.8 1.6 0.39 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EGO26074.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EGO26075.1 - 7.1e-27 94.2 0.0 1.7e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO26075.1 - 9.7e-19 67.2 0.0 8.4e-11 41.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EGO26075.1 - 6.3e-11 42.0 0.2 3.7e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO26075.1 - 0.0011 18.9 0.0 0.0089 15.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO26075.1 - 0.0089 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EGO26075.1 - 0.098 13.1 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EGO26075.1 - 0.61 10.3 0.0 0.61 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF4428 PF14471.1 EGO26077.1 - 0.051 13.3 0.4 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) AAA_12 PF13087.1 EGO26078.1 - 2.3e-42 144.6 0.0 2.8e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EGO26078.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 EGO26078.1 - 0.075 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EGO26078.1 - 0.14 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CTK3 PF12243.3 EGO26079.1 - 8.7e-44 148.5 0.1 3.3e-43 146.6 0.0 1.8 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EGO26079.1 - 1.5e-16 60.1 9.8 4.9e-15 55.3 6.8 2.5 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DRIM PF07539.7 EGO26080.1 - 2.1e-36 124.4 0.0 2.1e-35 121.2 0.0 2.7 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EGO26080.1 - 4.8e-05 23.1 5.1 30 5.0 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat EF-hand_9 PF14658.1 EGO26080.1 - 0.17 11.7 2.3 2.7 7.9 0.1 3.7 3 1 1 4 4 4 0 EF-hand domain CoA_transf_3 PF02515.12 EGO26081.1 - 8.5e-48 162.1 0.0 1.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF1805 PF08827.6 EGO26081.1 - 0.11 12.3 0.6 0.24 11.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF1479 PF07350.7 EGO26082.1 - 3e-142 473.9 0.0 3.4e-142 473.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Ceramidase_alk PF04734.8 EGO26083.1 - 1e-259 863.0 0.0 1.1e-259 862.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Lactonase PF10282.4 EGO26084.1 - 1.2e-55 189.0 0.0 1.4e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Aminotran_5 PF00266.14 EGO26085.1 - 3.9e-39 134.4 0.0 5.8e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO26085.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II UBACT PF02134.16 EGO26089.1 - 0.13 11.8 1.0 0.61 9.7 0.1 2.2 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein AKAP95 PF04988.7 EGO26090.1 - 0.061 13.0 0.2 0.15 11.8 0.2 1.6 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-H2C2_2 PF13465.1 EGO26090.1 - 1.2 9.6 7.5 1.4 9.3 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Cauli_VI PF01693.11 EGO26091.1 - 5.2e-07 29.5 0.0 7.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin Med3 PF11593.3 EGO26091.1 - 9.6 5.3 9.1 11 5.1 6.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Alpha_kinase PF02816.13 EGO26093.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 2 0 0 2 2 2 0 Alpha-kinase family VCBS PF13517.1 EGO26094.1 - 7.3e-08 32.6 17.0 0.0042 17.4 0.3 5.1 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.1 EGO26094.1 - 0.00013 21.1 0.3 8.5 5.9 0.0 4.1 4 0 0 4 4 4 2 EF hand DUF3471 PF11954.3 EGO26094.1 - 0.00014 21.6 0.0 23 4.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3471) Spore_GerQ PF09671.5 EGO26094.1 - 0.01 15.4 0.1 59 3.4 0.0 4.6 5 0 0 5 5 5 0 Spore coat protein (Spore_GerQ) EF-hand_6 PF13405.1 EGO26094.1 - 0.022 14.6 5.0 45 4.3 0.0 4.4 4 0 0 4 4 4 0 EF-hand domain Moricin PF06451.6 EGO26094.1 - 0.12 11.9 0.6 9.6 5.7 0.1 2.7 2 0 0 2 2 2 0 Moricin EF-hand_1 PF00036.27 EGO26094.1 - 0.23 10.8 2.9 70 3.0 0.0 3.9 4 0 0 4 4 4 0 EF hand DUF4374 PF14298.1 EGO26094.1 - 0.7 8.3 3.9 24 3.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4374) DUF1065 PF06358.6 EGO26095.1 - 0.073 12.8 0.8 0.15 11.8 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1065) MtrD PF04207.7 EGO26096.1 - 0.0053 16.1 0.3 0.0074 15.7 0.2 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D SPC25 PF06703.6 EGO26096.1 - 0.12 11.9 1.8 0.19 11.3 1.2 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MpPF26 PF07666.6 EGO26096.1 - 6.1 6.7 14.3 1.1 9.1 4.7 2.2 1 1 1 2 2 2 0 M penetrans paralogue family 26 FG-GAP PF01839.18 EGO26100.1 - 0.00082 18.9 2.9 1.3e+02 2.4 0.0 6.8 6 0 0 6 6 6 0 FG-GAP repeat zf-C2H2 PF00096.21 EGO26100.1 - 0.0041 17.3 0.2 0.45 10.9 0.0 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO26100.1 - 0.031 14.5 0.7 0.2 12.0 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger SAYSvFN PF10260.4 EGO26100.1 - 1.9 8.3 6.0 29 4.5 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Peptidase_M28 PF04389.12 EGO26106.1 - 1.1e-30 106.6 0.0 2.1e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EGO26106.1 - 0.0015 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Nicastrin PF05450.10 EGO26106.1 - 0.34 10.1 0.0 0.65 9.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin DUF2301 PF10063.4 EGO26108.1 - 0.017 15.2 0.6 0.017 15.2 0.4 2.3 2 1 1 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) ABC_tran PF00005.22 EGO26109.1 - 2e-26 92.9 0.0 3.3e-14 53.3 0.0 3.6 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGO26109.1 - 3.9e-08 33.6 0.0 0.002 18.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGO26109.1 - 4.3e-05 23.3 0.0 0.48 10.3 0.0 2.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGO26109.1 - 0.0048 16.3 0.1 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EGO26109.1 - 0.047 11.0 0.1 0.07 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.7 EGO26109.1 - 0.064 12.9 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain EF-hand_1 PF00036.27 EGO26111.1 - 2e-22 76.7 0.6 4e-05 22.5 0.0 4.5 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGO26111.1 - 3e-20 70.2 0.8 7.4e-05 22.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EGO26111.1 - 2.1e-17 62.9 1.9 6.1e-09 35.8 0.2 2.8 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO26111.1 - 9.2e-17 59.5 0.8 0.00016 20.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGO26111.1 - 5.9e-13 48.2 3.4 1.4e-06 27.8 0.0 4.5 3 2 2 5 5 5 5 EF-hand domain pair Bromodomain PF00439.20 EGO26112.1 - 1.8e-22 79.0 0.4 5.5e-22 77.4 0.2 1.9 1 1 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EGO26112.1 - 0.0003 20.4 0.1 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated ASC PF00858.19 EGO26112.1 - 0.27 9.8 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel WD40 PF00400.27 EGO26113.1 - 1.4e-32 110.3 6.9 2.4e-07 30.3 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGO26113.1 - 1.1e-05 25.2 0.3 0.0035 17.0 0.2 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EGO26113.1 - 0.0067 15.5 0.0 0.23 10.5 0.0 2.4 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal BRAP2 PF07576.7 EGO26113.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Sugar_tr PF00083.19 EGO26116.1 - 1.1e-106 357.1 11.9 1.3e-106 356.9 8.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO26116.1 - 1e-23 83.6 34.2 1.1e-19 70.3 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO26116.1 - 0.0054 14.9 0.9 0.0086 14.3 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RRM_6 PF14259.1 EGO26117.1 - 2.2e-35 120.4 0.5 4.4e-10 39.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO26117.1 - 8.2e-30 102.2 2.4 7.3e-09 35.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO26117.1 - 3.8e-19 68.2 0.0 0.0007 19.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO26117.1 - 6.6e-05 22.7 0.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif NID PF07292.8 EGO26117.1 - 0.021 14.8 0.0 0.38 10.8 0.0 2.5 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) HAUS6_N PF14661.1 EGO26118.1 - 6 6.1 11.9 0.62 9.3 0.1 3.2 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus Imm31 PF15595.1 EGO26119.1 - 0.0081 15.9 0.8 0.017 14.8 0.1 1.8 2 0 0 2 2 2 1 Immunity protein 31 DUF2972 PF11186.3 EGO26119.1 - 0.03 14.2 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) UCH PF00443.24 EGO26119.1 - 0.069 12.2 1.0 0.095 11.8 0.7 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Response_reg PF00072.19 EGO26120.1 - 6.1e-12 45.5 0.1 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain zf-CCHC_3 PF13917.1 EGO26122.1 - 0.00024 20.7 3.6 0.00056 19.5 2.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO26122.1 - 0.00032 20.4 5.2 0.00032 20.4 3.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EGO26123.1 - 6e-06 25.9 1.5 1.4e-05 24.8 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26123.1 - 0.017 15.1 0.3 0.017 15.1 0.2 2.1 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO26123.1 - 0.29 10.9 4.8 0.61 9.8 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle gag_pre-integrs PF13976.1 EGO26124.1 - 6.1e-10 38.6 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Avian_gp85 PF03708.9 EGO26124.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Metallophos PF00149.23 EGO26127.1 - 4.8e-08 32.6 4.7 8.6e-08 31.8 3.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2_4 PF13894.1 EGO26128.1 - 0.0041 17.3 5.1 0.15 12.4 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO26128.1 - 0.16 12.3 3.1 3.5 8.1 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Clat_adaptor_s PF01217.15 EGO26131.1 - 2e-18 66.5 0.0 3.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Bac_rhodopsin PF01036.13 EGO26132.1 - 4.8e-50 169.9 18.9 6.7e-50 169.4 13.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1304 PF06993.7 EGO26132.1 - 0.29 10.8 8.2 1.9 8.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) DUF360 PF04020.8 EGO26132.1 - 0.61 10.4 8.8 0.046 14.0 1.6 2.2 2 0 0 2 2 2 0 Membrane protein of unknown function Arteri_Gl PF00951.13 EGO26132.1 - 2.7 7.5 8.3 0.19 11.2 1.9 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF2892 PF11127.3 EGO26132.1 - 2.9 7.7 7.7 4.6 7.1 2.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF161 PF02588.10 EGO26132.1 - 3.3 8.0 14.2 16 5.8 4.5 3.5 3 1 0 3 3 3 0 Uncharacterized BCR, YitT family COG1284 zf-CHY PF05495.7 EGO26133.1 - 5.7e-16 58.4 18.9 7.8e-16 57.9 13.1 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 EGO26133.1 - 0.0064 16.1 0.9 0.024 14.2 0.6 2.0 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS ArfGap PF01412.13 EGO26133.1 - 0.0076 16.0 0.7 0.0076 16.0 0.5 1.4 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf zinc_ribbon_2 PF13240.1 EGO26133.1 - 0.074 12.5 0.3 0.074 12.5 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Tmemb_55A PF09788.4 EGO26133.1 - 0.14 11.2 6.1 0.16 11.1 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A DRP PF06044.7 EGO26133.1 - 0.29 10.0 2.0 0.46 9.4 1.4 1.4 1 1 0 1 1 1 0 Dam-replacing family Zn_Tnp_IS1595 PF12760.2 EGO26133.1 - 0.29 10.9 10.9 6.2 6.7 4.6 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain SIR2 PF02146.12 EGO26133.1 - 0.3 10.8 2.5 0.41 10.3 1.8 1.3 1 0 0 1 1 1 0 Sir2 family C1_4 PF07975.7 EGO26133.1 - 0.37 10.8 12.6 2.3 8.3 6.3 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 EGO26133.1 - 0.51 10.2 11.7 3.2 7.6 8.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGO26133.1 - 0.75 9.0 6.8 0.91 8.8 2.5 2.5 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EGO26133.1 - 0.89 9.2 9.5 4.8 6.8 6.6 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EGO26133.1 - 1 9.3 14.4 0.072 13.0 2.8 2.6 2 1 0 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 EGO26133.1 - 1.4 8.9 8.4 0.49 10.4 1.8 2.7 1 1 1 2 2 2 0 zinc-finger LIM PF00412.17 EGO26133.1 - 2.6 8.1 13.5 19 5.4 7.9 2.4 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EGO26133.1 - 6.2 6.8 7.4 2.2 8.2 0.1 3.2 3 1 1 4 4 4 0 C2H2-type zinc finger Cytochrome_C7 PF14522.1 EGO26133.1 - 7.2 6.3 13.2 14 5.3 9.2 1.5 1 1 0 1 1 1 0 Cytochrome c7 rve PF00665.21 EGO26135.1 - 0.00011 22.2 0.1 0.00045 20.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO26135.1 - 0.0064 16.3 0.1 0.0091 15.8 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 DUF3527 PF12043.3 EGO26137.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) CDC45 PF02724.9 EGO26139.1 - 0.12 10.4 12.5 0.16 9.9 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EGO26139.1 - 0.26 10.8 16.4 0.47 10.0 11.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EGO26139.1 - 2.9 5.7 16.4 1.6 6.5 9.5 1.7 2 0 0 2 2 2 0 Nop14-like family BSMAP PF12280.3 EGO26139.1 - 3.7 7.3 5.9 36 4.1 0.0 2.3 2 1 0 2 2 2 0 Brain specific membrane anchored protein Retrotrans_gag PF03732.12 EGO26140.1 - 5.4e-05 23.1 0.6 8e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.1 EGO26140.1 - 0.026 14.2 0.6 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain RhoGEF PF00621.15 EGO26141.1 - 2e-33 115.7 0.0 6e-33 114.2 0.0 1.8 2 1 0 2 2 2 1 RhoGEF domain Attachment_P66 PF11263.3 EGO26141.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 FAD_binding_4 PF01565.18 EGO26142.1 - 3.4e-12 46.0 0.3 3.8e-06 26.4 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 EGO26142.1 - 1.1e-07 31.5 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 EGO26142.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.5 EGO26142.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Uso1_p115_head PF04869.9 EGO26144.1 - 7.2e-45 153.0 0.0 1e-43 149.3 0.0 2.4 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EGO26144.1 - 8.7e-09 35.4 19.7 8.7e-09 35.4 13.7 1.7 2 0 0 2 2 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Cnd1 PF12717.2 EGO26144.1 - 0.00015 21.7 0.0 0.00052 19.9 0.0 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EGO26144.1 - 0.037 13.9 0.6 1.8 8.5 0.0 3.5 3 1 1 4 4 4 0 Importin-beta N-terminal domain HEAT PF02985.17 EGO26144.1 - 0.044 13.8 1.4 13 6.1 0.0 4.0 4 0 0 4 4 3 0 HEAT repeat Mo25 PF08569.6 EGO26144.1 - 0.053 12.5 7.8 0.096 11.7 0.2 2.5 2 0 0 2 2 2 0 Mo25-like DUF3361 PF11841.3 EGO26144.1 - 0.068 12.8 0.2 2.8 7.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) DUF3818 PF12825.2 EGO26144.1 - 0.1 11.2 4.4 0.13 10.9 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) IncA PF04156.9 EGO26144.1 - 0.12 11.9 12.7 0.28 10.7 8.8 1.6 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EGO26144.1 - 0.2 11.9 7.6 0.46 10.8 4.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EGO26144.1 - 0.87 8.4 5.4 1.5 7.7 3.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EGO26144.1 - 2.4 5.9 5.1 3.7 5.2 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EGO26144.1 - 4.6 6.7 10.7 1.4 8.4 4.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Aminotran_5 PF00266.14 EGO26145.1 - 1.3e-05 24.1 0.0 1.4e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V E1-E2_ATPase PF00122.15 EGO26146.1 - 7.4e-77 257.4 2.6 1.5e-76 256.4 1.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO26146.1 - 8e-36 123.2 0.2 8e-36 123.2 0.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO26146.1 - 5.2e-30 105.4 0.0 1.4e-29 104.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO26146.1 - 6.6e-15 54.8 0.0 2e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO26146.1 - 4.8e-14 52.9 0.0 1.7e-13 51.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO26146.1 - 1.1e-08 34.4 0.0 3.2e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO26146.1 - 7.5e-05 22.4 2.3 0.0008 19.0 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 EGO26146.1 - 0.00024 20.7 1.8 0.001 18.6 0.0 2.7 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC Ribosomal_L36 PF00444.13 EGO26146.1 - 0.16 12.0 0.0 2.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein L36 TrbC PF04956.8 EGO26146.1 - 4.7 7.2 15.7 6.1 6.9 0.9 4.0 4 0 0 4 4 4 0 TrbC/VIRB2 family Saccharop_dh PF03435.13 EGO26148.1 - 5e-22 78.4 0.0 8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EGO26148.1 - 4.7e-07 29.9 0.0 7.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO26148.1 - 4.6e-06 26.2 0.0 7.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EGO26148.1 - 0.00012 22.3 0.0 0.00054 20.2 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EGO26148.1 - 0.00014 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGO26148.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO26148.1 - 0.022 13.4 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EGO26148.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2480 PF10652.4 EGO26148.1 - 0.046 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) Shikimate_DH PF01488.15 EGO26148.1 - 0.057 13.5 0.0 11 6.1 0.0 2.4 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EGO26148.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 KR domain Aldo_ket_red PF00248.16 EGO26149.1 - 1e-52 178.7 0.0 1.2e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OEP PF02321.13 EGO26151.1 - 0.037 13.6 2.7 0.089 12.3 1.9 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein Ank_4 PF13637.1 EGO26153.1 - 2.6e-11 43.7 0.2 2e-05 24.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO26153.1 - 6.3e-11 42.1 0.3 9.1e-08 32.1 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO26153.1 - 3.8e-08 33.5 0.0 1e-07 32.2 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO26153.1 - 3.1e-06 26.6 0.1 0.042 13.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EGO26153.1 - 4.9e-06 26.2 0.1 0.056 13.7 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeat PseudoU_synth_2 PF00849.17 EGO26154.1 - 7.2e-29 100.7 0.0 1.1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase p450 PF00067.17 EGO26156.1 - 2.4e-72 243.9 0.0 7.3e-72 242.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Fascin PF06268.8 EGO26157.1 - 0.00018 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.7 EGO26157.1 - 0.087 12.2 0.1 1.9 7.9 0.1 2.0 1 1 1 2 2 2 0 FRG1-like family Ank_2 PF12796.2 EGO26161.1 - 4.7e-06 26.8 0.0 7.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO26161.1 - 1.4e-05 25.4 0.2 0.016 15.6 0.0 2.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO26161.1 - 1.8e-05 24.2 0.2 7.2e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGO26161.1 - 0.00015 21.8 0.1 0.00044 20.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO26161.1 - 0.00035 20.5 0.1 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat VCBS PF13517.1 EGO26165.1 - 1.4e-12 47.7 23.2 0.00029 21.1 0.3 5.4 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.1 EGO26165.1 - 9.8e-06 24.6 4.6 3 7.3 0.0 5.5 6 0 0 6 6 6 2 EF hand DUF3471 PF11954.3 EGO26165.1 - 1.4e-05 24.8 0.0 15 5.5 0.0 5.1 5 1 0 6 6 6 1 Domain of unknown function (DUF3471) DUF3642 PF12182.3 EGO26165.1 - 0.056 13.8 0.0 17 5.9 0.0 3.8 4 0 0 4 4 4 0 Bacterial lipoprotein EF-hand_6 PF13405.1 EGO26165.1 - 0.078 12.9 11.6 44 4.3 0.0 5.7 6 0 0 6 6 6 0 EF-hand domain Moricin PF06451.6 EGO26165.1 - 0.25 10.8 1.2 10 5.6 0.0 3.1 3 0 0 3 3 3 0 Moricin EF-hand_1 PF00036.27 EGO26165.1 - 0.31 10.4 7.3 52 3.4 0.0 5.1 6 0 0 6 6 6 0 EF hand Aldo_ket_red PF00248.16 EGO26166.1 - 4.8e-44 150.2 0.0 6.2e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Lipocalin_3 PF12702.2 EGO26166.1 - 0.0041 17.1 0.0 0.072 13.1 0.0 2.2 2 0 0 2 2 2 1 Lipocalin-like HyaE PF07449.6 EGO26166.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Abhydrolase_6 PF12697.2 EGO26167.1 - 2.2e-21 76.8 0.1 2.6e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO26167.1 - 3.7e-06 26.7 0.0 8.9e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DPBB_1 PF03330.13 EGO26173.1 - 1.3e-09 37.8 0.4 3.9e-09 36.3 0.2 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4473 PF14747.1 EGO26173.1 - 0.084 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) NifU PF01106.12 EGO26173.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 NifU-like domain F-box-like PF12937.2 EGO26174.1 - 0.007 16.0 0.3 0.22 11.2 0.0 2.8 2 1 0 2 2 2 1 F-box-like Cytochrom_C PF00034.16 EGO26175.1 - 1.4e-08 35.4 0.0 2.1e-08 34.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGO26175.1 - 3e-07 30.5 0.3 1.6e-06 28.1 0.2 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C1 PF02167.10 EGO26175.1 - 0.016 14.9 0.3 0.88 9.1 0.1 2.0 1 1 1 2 2 2 0 Cytochrome C1 family Cytochrom_C550 PF14495.1 EGO26175.1 - 0.018 14.4 0.3 0.13 11.7 0.0 2.1 2 1 0 2 2 2 0 Cytochrome c-550 domain UPF0128 PF03673.8 EGO26175.1 - 0.039 13.2 0.1 0.044 13.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Docking PF08990.6 EGO26175.1 - 0.045 13.0 1.4 3.4 6.9 0.3 2.2 2 0 0 2 2 2 0 Erythronolide synthase docking p450 PF00067.17 EGO26176.1 - 1.4e-76 257.8 0.0 3.4e-76 256.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 EGO26177.1 - 2.5e-48 164.9 23.2 1.9e-21 76.6 3.4 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EGO26177.1 - 1.3e-42 145.3 0.0 7.3e-30 104.0 0.0 2.9 2 1 0 2 2 2 2 ABC transporter T2SE PF00437.15 EGO26177.1 - 4.6e-08 32.2 0.1 0.0044 15.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 EGO26177.1 - 5.9e-08 33.0 0.0 0.036 14.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EGO26177.1 - 3.3e-07 29.9 0.0 0.0028 17.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO26177.1 - 1.1e-05 24.8 0.3 0.21 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO26177.1 - 3.6e-05 23.8 0.3 0.26 11.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EGO26177.1 - 4.5e-05 23.8 0.0 0.023 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGO26177.1 - 5.2e-05 22.5 6.7 0.0058 15.8 1.1 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGO26177.1 - 0.0005 20.2 0.4 7.6 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EGO26177.1 - 0.0041 16.8 0.3 0.59 9.9 0.0 3.5 4 0 0 4 4 3 1 Part of AAA domain AAA_10 PF12846.2 EGO26177.1 - 0.0052 16.2 0.1 0.68 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EGO26177.1 - 0.0055 17.5 0.0 3 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGO26177.1 - 0.0055 16.4 0.0 0.13 11.8 0.0 2.5 3 0 0 3 3 2 1 Archaeal ATPase MobB PF03205.9 EGO26177.1 - 0.0063 16.2 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EGO26177.1 - 0.0087 16.3 0.1 7.3 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGO26177.1 - 0.0091 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EGO26177.1 - 0.011 15.2 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EGO26177.1 - 0.016 15.7 0.1 7.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EGO26177.1 - 0.017 14.9 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EGO26177.1 - 0.03 14.2 0.4 7.3 6.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGO26177.1 - 0.04 13.8 0.1 3 7.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGO26177.1 - 0.056 12.5 0.1 4.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 EGO26177.1 - 0.15 11.2 0.0 23 4.1 0.0 2.5 3 0 0 3 3 2 0 PhoH-like protein Mt_ATP-synt_B PF05405.9 EGO26177.1 - 0.21 11.0 0.1 0.62 9.5 0.0 1.7 2 0 0 2 2 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF258 PF03193.11 EGO26177.1 - 0.39 9.9 0.0 26 3.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Aldo_ket_red PF00248.16 EGO26178.1 - 4.6e-40 137.2 0.0 5.9e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HyaE PF07449.6 EGO26178.1 - 0.00089 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Lipocalin_3 PF12702.2 EGO26178.1 - 0.033 14.2 0.2 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Lipocalin-like Peptidase_M18 PF02127.10 EGO26179.1 - 6.9e-152 505.8 0.0 7.8e-152 505.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EGO26179.1 - 0.022 13.5 0.0 0.25 10.0 0.1 2.2 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase AMP-binding PF00501.23 EGO26180.1 - 6.4e-72 242.2 0.0 7.6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO26180.1 - 2.8e-11 44.1 0.0 7.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF330 PF03886.8 EGO26180.1 - 0.00079 18.8 0.0 0.0025 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF330) Herpes_gE PF02480.11 EGO26181.1 - 0.061 11.5 0.0 0.081 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3554 PF12074.3 EGO26182.1 - 1.5e-47 162.7 2.4 1.5e-47 162.7 1.7 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 EGO26182.1 - 6.9e-31 105.9 28.9 1.2e-05 25.6 0.1 17.1 16 4 4 20 20 20 8 HEAT-like repeat HEAT_2 PF13646.1 EGO26182.1 - 7.6e-31 106.2 29.5 1.7e-05 25.0 0.0 13.7 8 3 3 13 13 13 7 HEAT repeats HEAT PF02985.17 EGO26182.1 - 4.1e-24 82.4 22.9 0.17 12.0 0.1 17.2 20 0 0 20 20 20 7 HEAT repeat CLASP_N PF12348.3 EGO26182.1 - 3.9e-10 39.4 0.0 0.00056 19.3 0.0 6.5 4 1 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EGO26182.1 - 7.4e-07 29.4 0.0 2.9 8.3 0.0 7.1 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGO26182.1 - 0.00013 21.8 0.0 11 5.8 0.0 6.6 5 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EGO26182.1 - 0.0013 18.6 0.2 0.2 11.6 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RsbU_N PF08673.5 EGO26182.1 - 0.32 11.0 0.8 71 3.5 0.0 3.8 4 0 0 4 4 4 0 Phosphoserine phosphatase RsbU, N-terminal domain Birna_VP3 PF01767.11 EGO26182.1 - 0.57 9.7 0.7 1.1 8.7 0.0 1.8 2 0 0 2 2 2 0 Birnavirus VP3 protein NIF PF03031.13 EGO26184.1 - 5.3e-37 126.9 0.1 8.7e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ATP-synt_E PF05680.7 EGO26184.1 - 0.12 12.3 0.3 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase E chain DUF1180 PF06679.7 EGO26184.1 - 0.38 10.6 1.8 0.74 9.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NAD_binding_5 PF07994.7 EGO26185.1 - 7.8e-105 350.5 0.0 9.2e-105 350.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGO26185.1 - 8.5e-45 151.1 0.0 1.6e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase HSBP1 PF06825.7 EGO26188.1 - 0.067 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 MtrG PF04210.8 EGO26188.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Y_phosphatase3 PF13350.1 EGO26189.1 - 4.6e-44 150.5 0.0 1.1e-43 149.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO26189.1 - 1.2e-08 34.9 0.2 3.3e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 EGO26189.1 - 0.0056 16.7 0.1 0.025 14.6 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EGO26189.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EGO26189.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 EGO26189.1 - 0.08 12.2 0.0 0.18 11.1 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family DM PF00751.13 EGO26190.1 - 0.011 15.2 7.6 0.031 13.8 0.3 3.0 3 0 0 3 3 3 0 DM DNA binding domain zf-H2C2_2 PF13465.1 EGO26190.1 - 0.11 12.8 0.2 0.11 12.8 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EGO26190.1 - 0.21 11.9 10.3 0.29 11.5 0.8 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO26190.1 - 0.21 11.9 9.4 17 6.0 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGO26190.1 - 2.2 8.6 7.0 18 5.7 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RhoGAP PF00620.22 EGO26191.1 - 4.1e-14 52.4 0.0 3.1e-13 49.6 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain zf-C4H2 PF10146.4 EGO26191.1 - 0.13 12.2 5.0 0.34 10.9 3.5 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.7 EGO26191.1 - 1.9 8.2 5.4 5.1 6.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CFEM PF05730.6 EGO26192.1 - 2.6e-10 39.9 14.3 4.4e-10 39.2 9.9 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EGO26192.1 - 0.07 13.1 1.9 0.07 13.1 1.3 1.8 3 0 0 3 3 3 0 Gamma-thionin family Toxin_3 PF00537.13 EGO26192.1 - 1.3 8.9 6.9 0.2 11.5 1.8 1.8 1 1 0 1 1 1 0 Scorpion toxin-like domain Extensin_2 PF04554.8 EGO26193.1 - 2.1 8.2 6.6 3.6 7.5 4.6 1.4 1 1 0 1 1 1 0 Extensin-like region G-alpha PF00503.15 EGO26194.1 - 7.6e-127 423.1 2.3 9.2e-127 422.9 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO26194.1 - 5e-15 55.1 0.4 9.6e-10 37.9 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO26194.1 - 0.0014 17.8 1.0 0.58 9.2 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO26194.1 - 0.0061 17.0 0.2 0.86 10.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGO26194.1 - 0.037 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGO26194.1 - 0.073 12.5 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO26194.1 - 0.14 12.1 0.0 9.5 6.2 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase HEAT PF02985.17 EGO26195.1 - 4.7e-19 66.6 8.6 1.8e-05 24.4 0.0 9.1 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EGO26195.1 - 6.6e-16 58.2 18.1 3e-06 27.5 0.0 9.8 10 1 1 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 EGO26195.1 - 3.1e-13 49.8 10.2 6.4e-07 29.5 0.1 5.9 4 1 3 7 7 7 5 HEAT repeats RIX1 PF08167.7 EGO26195.1 - 4e-11 42.8 0.7 3.7e-06 26.7 0.0 4.5 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 EGO26195.1 - 1e-08 35.4 0.3 0.00034 20.9 0.0 4.3 3 1 2 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGO26195.1 - 0.00019 19.8 0.4 0.00097 17.5 0.1 2.3 2 1 1 3 3 3 1 Adaptin N terminal region TFCD_C PF12612.3 EGO26195.1 - 0.00049 19.5 0.1 0.31 10.4 0.1 3.3 3 1 0 3 3 3 2 Tubulin folding cofactor D C terminal MMS19_C PF12460.3 EGO26195.1 - 0.015 14.0 6.6 0.043 12.5 0.0 3.6 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Arm PF00514.18 EGO26195.1 - 0.026 14.3 1.8 38 4.3 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3328 PF11807.3 EGO26196.1 - 3.5e-20 72.6 6.1 9.1e-20 71.2 4.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.19 EGO26197.1 - 2.5e-12 46.6 0.0 5e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO26197.1 - 3e-06 27.3 0.0 7.1e-05 22.9 0.0 2.6 1 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO26197.1 - 4.2e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO26197.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO26197.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EGO26197.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase But2 PF09792.4 EGO26198.1 - 6.4e-06 25.9 0.0 1.6e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain BTP PF05232.7 EGO26199.1 - 0.039 13.6 1.4 0.86 9.3 0.4 2.1 1 1 1 2 2 2 0 Bacterial Transmembrane Pair family zf-MYND PF01753.13 EGO26200.1 - 1e-10 41.2 16.3 2.1e-10 40.2 11.3 1.6 1 0 0 1 1 1 1 MYND finger DUF2847 PF11009.3 EGO26202.1 - 0.09 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Retrotrans_gag PF03732.12 EGO26204.1 - 2.8e-06 27.2 2.8 6.7e-06 26.0 0.0 2.6 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO26204.1 - 0.032 14.1 2.3 0.069 13.1 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3328 PF11807.3 EGO26207.1 - 1.1e-17 64.4 0.1 1.4e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC2_membrane PF01061.19 EGO26209.1 - 5.2e-83 277.3 70.2 1.5e-43 148.4 17.5 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGO26209.1 - 3e-36 124.7 0.0 1.8e-17 63.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGO26209.1 - 8.4e-32 108.9 12.5 7e-26 89.8 0.0 3.3 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGO26209.1 - 5.5e-09 36.0 0.0 1.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGO26209.1 - 7.6e-09 35.2 0.0 0.00054 19.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGO26209.1 - 4.2e-08 33.3 0.2 0.00015 21.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGO26209.1 - 6.9e-07 28.5 0.0 3.4e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO26209.1 - 9.4e-07 29.0 0.1 0.031 14.4 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGO26209.1 - 4.6e-05 23.3 0.1 0.07 13.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO26209.1 - 0.00012 21.5 0.5 0.045 13.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EGO26209.1 - 0.00018 21.0 0.1 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EGO26209.1 - 0.00025 20.7 0.2 0.096 12.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EGO26209.1 - 0.00029 20.3 0.1 2.9 7.2 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EGO26209.1 - 0.0007 19.8 0.0 0.36 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGO26209.1 - 0.0014 17.7 48.6 0.0018 17.3 16.8 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_28 PF13521.1 EGO26209.1 - 0.0016 18.4 0.7 0.33 10.9 0.3 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO26209.1 - 0.0017 18.3 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGO26209.1 - 0.0038 17.0 0.0 1.7 8.6 0.0 2.9 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EGO26209.1 - 0.0039 17.2 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EGO26209.1 - 0.0048 16.5 2.1 0.063 12.9 0.3 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EGO26209.1 - 0.0049 17.6 0.0 0.53 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO26209.1 - 0.0093 15.6 2.8 0.71 9.6 0.9 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EGO26209.1 - 0.0094 15.4 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family PDR_assoc PF08370.6 EGO26209.1 - 0.019 14.4 0.5 0.019 14.4 0.3 3.1 3 0 0 3 3 2 0 Plant PDR ABC transporter associated PduV-EutP PF10662.4 EGO26209.1 - 0.03 13.7 0.4 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EGO26209.1 - 0.033 13.4 0.0 1.4 8.1 0.0 3.0 5 0 0 5 5 4 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EGO26209.1 - 0.047 13.3 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EGO26209.1 - 0.069 13.3 0.3 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGO26209.1 - 0.071 13.2 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EGO26209.1 - 0.088 12.5 0.0 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EGO26209.1 - 0.11 12.0 0.5 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EGO26209.1 - 0.15 12.5 0.0 7.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Septin PF00735.13 EGO26209.1 - 0.18 10.8 0.2 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 EGO26209.1 - 0.22 11.8 0.1 0.43 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Oxidored_FMN PF00724.15 EGO26212.1 - 4.1e-74 249.6 0.0 4.8e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.8 EGO26212.1 - 0.00072 18.9 0.1 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) AP_endonuc_2 PF01261.19 EGO26212.1 - 0.11 11.8 0.0 0.3 10.3 0.0 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Oxidored_FMN PF00724.15 EGO26213.1 - 7.5e-69 232.3 0.0 1e-68 231.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.8 EGO26213.1 - 0.0012 18.2 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) POX PF07526.6 EGO26214.1 - 0.049 13.8 4.0 0.065 13.4 2.4 1.4 1 1 0 1 1 1 0 Associated with HOX DUF4407 PF14362.1 EGO26214.1 - 0.065 12.1 2.8 0.11 11.4 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3972 PF13118.1 EGO26214.1 - 0.17 11.9 6.7 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) LMBR1 PF04791.11 EGO26214.1 - 0.38 9.2 5.0 0.45 9.0 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lipase_chap PF03280.9 EGO26214.1 - 1.7 8.0 11.1 9 5.7 7.6 1.9 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein RNA_pol_A_bac PF01000.21 EGO26217.1 - 8e-23 80.7 0.0 1.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGO26217.1 - 1.8e-12 46.1 0.0 2.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MFS_1 PF07690.11 EGO26219.1 - 4.3e-36 124.3 34.3 3.4e-35 121.4 23.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO26219.1 - 7.5e-11 40.9 14.9 9.9e-11 40.5 10.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO26219.1 - 6.5e-10 38.1 16.1 4.8e-09 35.3 3.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 EGO26219.1 - 0.068 11.2 6.9 0.11 10.6 4.6 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.11 EGO26220.1 - 0.016 13.9 12.1 0.019 13.7 7.6 1.6 2 0 0 2 2 2 0 Major Facilitator Superfamily Bax1-I PF01027.15 EGO26220.1 - 7.8 6.0 12.6 8.4 5.9 5.5 2.6 2 1 1 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Antimicrobial_5 PF08026.6 EGO26221.1 - 0.87 9.4 5.3 2.2 8.1 3.7 1.6 1 0 0 1 1 1 0 Bee antimicrobial peptide tRNA-synt_2 PF00152.15 EGO26222.1 - 5.1e-70 235.8 0.0 8e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO26222.1 - 5.3e-10 39.0 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ish1 PF10281.4 EGO26222.1 - 0.19 11.8 1.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Evr1_Alr PF04777.8 EGO26223.1 - 8.1e-22 76.9 0.1 1e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family CAP59_mtransfer PF11735.3 EGO26224.1 - 5.4e-57 192.7 0.0 8.1e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Steroid_dh PF02544.11 EGO26225.1 - 5.8e-27 94.2 4.7 1.9e-14 53.6 0.3 3.2 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGO26225.1 - 0.00015 21.1 1.0 0.00032 20.0 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) PIG-P PF08510.7 EGO26226.1 - 0.75 9.4 6.7 3.2 7.4 4.6 2.1 1 1 0 1 1 1 0 PIG-P STE3 PF02076.10 EGO26228.1 - 5.3e-75 252.1 14.3 6.2e-75 251.9 9.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor PY_rept_46 PF09689.5 EGO26230.1 - 0.099 12.9 0.6 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) INSIG PF07281.7 EGO26232.1 - 0.046 13.0 0.7 0.082 12.2 0.5 1.4 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) InaF-motif PF15018.1 EGO26232.1 - 3.3 7.2 7.3 0.85 9.1 2.0 2.4 2 0 0 2 2 2 0 TRP-interacting helix 2-Hacid_dh_C PF02826.14 EGO26233.1 - 8.8e-53 178.0 0.0 1.2e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO26233.1 - 5.8e-17 61.4 0.0 7.5e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO26233.1 - 3.1e-05 23.8 0.0 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EGO26233.1 - 0.0092 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase IlvN PF07991.7 EGO26233.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ank_4 PF13637.1 EGO26234.1 - 0.0025 18.2 0.7 6.1 7.4 0.1 5.2 4 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO26234.1 - 0.0056 16.9 0.0 0.071 13.4 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO26234.1 - 0.084 13.1 0.0 13 6.3 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat Sipho_Gp157 PF05565.6 EGO26234.1 - 0.24 10.9 10.5 0.47 10.0 7.3 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 Dimer_Tnp_hAT PF05699.9 EGO26234.1 - 3 7.5 9.8 5.5 6.6 0.1 4.4 3 1 2 5 5 5 0 hAT family C-terminal dimerisation region Sel1 PF08238.7 EGO26236.1 - 1.6e-31 107.9 43.0 2.4e-06 27.9 0.5 9.8 9 1 0 9 9 9 7 Sel1 repeat TPR_11 PF13414.1 EGO26236.1 - 1.6e-05 24.4 9.8 0.071 12.7 0.3 4.5 4 0 0 4 4 4 3 TPR repeat Utp13 PF08625.6 EGO26236.1 - 0.089 12.4 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain TPR_2 PF07719.12 EGO26236.1 - 0.12 12.3 0.0 0.12 12.3 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO26236.1 - 0.45 11.2 0.1 0.45 11.2 0.0 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO26236.1 - 0.69 10.7 12.8 4.8 8.1 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26236.1 - 3.6 7.3 12.4 13 5.6 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.17 EGO26237.1 - 1.6e-10 39.8 21.6 9.8e-05 21.5 0.3 6.3 6 1 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat DIL PF01843.14 EGO26237.1 - 0.015 15.1 0.1 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 DIL domain ATP-synt_B PF00430.13 EGO26237.1 - 0.069 12.9 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RNase_T PF00929.19 EGO26238.1 - 7.7e-28 97.8 0.0 9.1e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease TctA PF01970.11 EGO26240.1 - 0.036 12.4 0.0 0.043 12.2 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Transposase_20 PF02371.11 EGO26242.1 - 0.3 11.1 0.2 0.3 11.1 0.1 1.7 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family RRP7 PF12923.2 EGO26242.1 - 1 9.3 6.6 1.1 9.2 4.4 1.3 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) SRP-alpha_N PF04086.8 EGO26242.1 - 4.5 6.5 8.9 5 6.4 6.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1917 PF08939.5 EGO26244.1 - 2.8e-28 99.3 0.9 2.8e-28 99.3 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) SUFU_C PF12470.3 EGO26244.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.7 2 1 1 3 3 3 0 Suppressor of Fused Gli/Ci N terminal binding domain Fcf1 PF04900.7 EGO26246.1 - 6.5e-40 135.3 0.6 6.5e-40 135.3 0.4 1.6 2 0 0 2 2 2 1 Fcf1 5_3_exonuc PF01367.15 EGO26246.1 - 0.077 13.2 0.2 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Lyase_aromatic PF00221.14 EGO26247.1 - 1e-138 462.7 5.6 1.3e-138 462.4 3.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase CPSase_L_D2 PF02786.12 EGO26248.1 - 6.9e-101 335.8 0.0 2.4e-76 255.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGO26248.1 - 2.2e-40 137.2 0.5 4.2e-40 136.3 0.3 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGO26248.1 - 4.3e-36 123.3 0.0 2.6e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGO26248.1 - 6.7e-35 120.4 0.0 9.5e-19 67.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGO26248.1 - 1.8e-20 72.9 0.0 1.2e-10 40.7 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGO26248.1 - 4.2e-16 58.7 0.0 6.9e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO26248.1 - 1.5e-12 47.3 0.0 5.2e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGO26248.1 - 1.9e-07 30.7 0.0 0.0083 15.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EGO26248.1 - 6.2e-06 25.5 0.1 0.029 13.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EGO26248.1 - 0.0016 18.3 0.0 0.032 14.0 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 EGO26248.1 - 0.0089 15.9 0.0 0.088 12.7 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain FCP1_C PF09309.5 EGO26249.1 - 1.1 8.4 11.4 0.036 13.3 3.2 1.8 2 0 0 2 2 2 0 FCP1, C-terminal DUF601 PF04642.7 EGO26249.1 - 5.4 6.2 13.6 0.061 12.6 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF601 Serglycin PF04360.7 EGO26251.1 - 2.4e-05 24.1 0.3 4.3e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Serglycin Lzipper-MIP1 PF14389.1 EGO26251.1 - 0.017 15.2 0.1 0.42 10.7 0.2 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 SAP PF02037.22 EGO26251.1 - 0.053 13.0 1.0 0.33 10.5 0.4 2.6 2 0 0 2 2 2 0 SAP domain Transglut_core3 PF13471.1 EGO26251.1 - 0.13 12.0 0.4 0.32 10.7 0.3 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pox_RNA_Pol_19 PF05320.7 EGO26251.1 - 0.59 9.8 7.5 14 5.4 5.1 2.1 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Abhydrolase_6 PF12697.2 EGO26253.1 - 2.4e-09 37.4 0.2 5.8e-09 36.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO26253.1 - 0.00011 21.9 0.0 0.00043 20.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_49 PF13896.1 EGO26254.1 - 9.9e-36 123.4 4.8 1.5e-27 96.5 0.4 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EGO26254.1 - 0.05 12.6 1.1 0.075 12.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF4233 PF14017.1 EGO26256.1 - 0.42 10.5 9.0 0.031 14.2 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) TB2_DP1_HVA22 PF03134.14 EGO26256.1 - 0.77 9.5 4.7 0.17 11.6 0.8 1.8 2 0 0 2 2 2 0 TB2/DP1, HVA22 family DUF2583 PF10762.4 EGO26256.1 - 2.5 8.3 5.5 0.4 10.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) TniQ PF06527.6 EGO26257.1 - 0.033 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 TniQ Rer1 PF03248.8 EGO26259.1 - 7.2e-80 266.7 0.3 8.2e-80 266.5 0.2 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 EGO26259.1 - 0.00021 20.8 0.3 0.00026 20.4 0.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AAA_17 PF13207.1 EGO26260.1 - 0.0021 18.8 0.1 0.0051 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO26260.1 - 0.0099 15.6 0.1 0.09 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGO26260.1 - 0.013 14.6 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EGO26260.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGO26260.1 - 0.021 13.6 0.0 0.041 12.6 0.0 1.5 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 EGO26260.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO26260.1 - 0.03 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EGO26260.1 - 0.11 12.2 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EGO26260.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain CIAPIN1 PF05093.8 EGO26263.1 - 0.08 13.0 0.4 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Acetyltransf_1 PF00583.19 EGO26264.1 - 1.7e-07 31.1 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO26264.1 - 7e-05 22.5 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGO26264.1 - 0.0055 16.8 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO26264.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO26264.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1442 PF07279.6 EGO26267.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) AAA_16 PF13191.1 EGO26268.1 - 5.5e-05 23.2 1.3 0.00053 20.0 0.4 2.6 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EGO26268.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EGO26268.1 - 0.019 15.1 0.3 0.1 12.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO26268.1 - 0.024 14.1 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO26268.1 - 0.028 13.8 1.6 0.29 10.4 0.1 3.1 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EGO26268.1 - 0.08 12.8 0.1 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain zf-CCCH_2 PF14608.1 EGO26269.1 - 2.6e-05 24.0 39.8 0.006 16.5 3.5 4.7 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type TraT PF05818.7 EGO26269.1 - 0.033 13.6 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Cyt-b5 PF00173.23 EGO26272.1 - 4.5e-19 68.0 0.0 5.5e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SSP160 PF06933.6 EGO26274.1 - 1.7 6.5 10.4 1.6 6.6 7.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 EGO26274.1 - 2 8.4 7.0 2.2 8.3 4.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3911 PF13050.1 EGO26274.1 - 3.4 7.8 5.4 4.7 7.4 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) zf-CCHC PF00098.18 EGO26275.1 - 2.8e-08 33.2 1.1 4e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO26275.1 - 0.077 12.6 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO26275.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle GPI-anchored PF10342.4 EGO26279.1 - 0.00021 21.6 0.3 0.00029 21.2 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tim17 PF02466.14 EGO26281.1 - 3.4e-34 117.6 9.4 4.3e-34 117.3 6.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TSP9 PF11493.3 EGO26281.1 - 0.012 16.1 2.5 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 DUF543 PF04418.7 EGO26281.1 - 0.057 13.3 0.5 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Arrestin_C PF02752.17 EGO26282.1 - 7.3e-15 55.2 0.0 1.1e-13 51.4 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGO26282.1 - 3.1e-14 53.0 0.0 2.8e-10 40.1 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain hSH3 PF14603.1 EGO26283.1 - 0.078 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain Jiraiya PF15038.1 EGO26283.1 - 6.1 6.2 11.0 19 4.6 2.8 3.0 2 1 1 3 3 3 0 Jiraiya DUF2338 PF10100.4 EGO26285.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Cauli_VI PF01693.11 EGO26286.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin VHL PF01847.11 EGO26290.1 - 0.0052 16.3 0.0 0.0065 16.0 0.0 1.1 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein IL13 PF03487.8 EGO26292.1 - 0.042 13.5 0.1 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin-13 DUF3636 PF12331.3 EGO26292.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) MethyltransfD12 PF02086.10 EGO26293.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Amidohydro_1 PF01979.15 EGO26296.1 - 3.2e-17 63.2 0.0 1.2e-11 44.9 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGO26296.1 - 1.5e-12 48.1 0.4 3.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EGO26296.1 - 2e-06 27.2 0.1 4.5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGO26296.1 - 1.8e-05 24.4 0.1 9.5e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidase PF01425.16 EGO26297.1 - 1.1e-84 284.8 0.0 1.4e-84 284.5 0.0 1.1 1 0 0 1 1 1 1 Amidase NMO PF03060.10 EGO26302.1 - 2.8e-49 168.0 2.2 1.4e-47 162.5 1.5 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO26302.1 - 1.8e-09 36.9 0.1 0.00039 19.4 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO26302.1 - 4e-08 32.5 1.6 4.7e-08 32.2 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EGO26302.1 - 2.9e-05 23.1 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EGO26302.1 - 0.0019 17.1 0.4 0.15 10.9 0.1 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase CPSase_L_D2 PF02786.12 EGO26302.1 - 0.0026 17.0 0.6 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain His_biosynth PF00977.16 EGO26302.1 - 0.014 14.7 0.5 0.028 13.7 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein NADH_oxidored PF08040.6 EGO26302.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 MNLL subunit PcrB PF01884.12 EGO26302.1 - 0.13 11.4 0.9 2.3 7.3 0.0 2.6 2 1 1 3 3 3 0 PcrB family Aminotran_1_2 PF00155.16 EGO26303.1 - 1.4e-37 129.4 0.0 2.4e-37 128.7 0.0 1.4 1 1 1 2 2 2 1 Aminotransferase class I and II DUF2977 PF11192.3 EGO26303.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) Beta_elim_lyase PF01212.16 EGO26303.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.17 EGO26304.1 - 2.9e-60 204.1 0.0 3.5e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO26305.1 - 1.9e-85 287.1 0.0 2.1e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PQ-loop PF04193.9 EGO26306.1 - 2.4e-05 23.7 1.1 2.4e-05 23.7 0.7 4.0 3 1 2 5 5 5 2 PQ loop repeat DUF3533 PF12051.3 EGO26307.1 - 8.2e-76 255.2 21.1 9.7e-76 254.9 14.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TRI5 PF06330.6 EGO26308.1 - 2.3e-07 29.8 0.1 0.046 12.3 0.0 3.0 2 1 1 3 3 3 3 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 EGO26308.1 - 0.0032 16.7 0.4 2.8 7.0 0.0 2.9 3 0 0 3 3 3 2 Terpene synthase family, metal binding domain Oxidored_FMN PF00724.15 EGO26309.1 - 3.8e-72 243.1 0.0 4.8e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.8 EGO26309.1 - 0.001 18.4 0.1 0.0022 17.3 0.1 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) p450 PF00067.17 EGO26310.1 - 1.3e-17 63.4 0.0 1.5e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO26311.1 - 4.1e-19 68.4 0.0 4.9e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.13 EGO26313.1 - 2.1e-28 99.2 0.0 3.2e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein IGF2_C PF08365.6 EGO26314.1 - 0.11 12.2 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide OPT PF03169.10 EGO26315.1 - 9.7e-188 625.4 51.1 1.1e-187 625.2 35.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EVC2_like PF12297.3 EGO26316.1 - 0.095 11.3 0.3 0.12 11.0 0.2 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF4098 PF13345.1 EGO26317.1 - 0.034 14.0 4.6 7.4 6.5 0.1 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4098) LSM PF01423.17 EGO26318.1 - 2.3e-15 55.8 0.0 3.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain F-box-like PF12937.2 EGO26319.1 - 4.1e-07 29.6 1.6 0.0011 18.5 0.1 2.9 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.1 EGO26319.1 - 0.23 11.2 3.2 2.1 8.1 0.6 3.0 2 1 1 3 3 3 0 Leucine rich repeat DUF3628 PF12300.3 EGO26321.1 - 0.047 13.7 1.5 0.064 13.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) FAM194 PF14977.1 EGO26321.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 FAM194 protein Pantoate_transf PF02548.10 EGO26322.1 - 1.2e-100 336.0 0.1 1.4e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGO26322.1 - 4.5e-07 29.3 0.1 1.1e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase SnoaL_2 PF12680.2 EGO26323.1 - 9.2e-06 26.0 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain BRAP2 PF07576.7 EGO26323.1 - 0.0039 16.7 0.1 0.0063 16.0 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 SnoaL PF07366.7 EGO26323.1 - 0.026 14.0 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EGO26324.1 - 0.0022 18.3 0.0 0.0039 17.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain Kri1_C PF12936.2 EGO26325.1 - 1.5e-24 85.7 0.0 1.5e-24 85.7 0.0 5.1 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EGO26325.1 - 3.8e-24 84.8 6.6 3.8e-24 84.8 4.6 6.3 5 1 1 6 6 6 1 KRI1-like family LRR_8 PF13855.1 EGO26326.1 - 1.3e-06 28.0 7.8 1.3e-05 24.7 0.1 3.1 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EGO26326.1 - 0.00047 19.7 13.9 2.2 7.9 0.1 4.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.7 EGO26326.1 - 0.007 16.3 3.5 0.022 14.7 2.5 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.28 EGO26326.1 - 0.074 13.1 4.0 11 6.5 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat Calpain_III PF01067.17 EGO26327.1 - 8.1e-22 77.4 0.0 8.8e-10 38.4 0.0 4.6 3 2 0 3 3 3 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 EGO26327.1 - 1e-16 60.7 0.0 1.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 EGO26327.1 - 0.00015 21.6 0.4 0.00029 20.6 0.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Init_tRNA_PT PF04179.7 EGO26328.1 - 2e-82 277.4 0.0 3.7e-53 181.0 0.0 3.0 2 1 1 3 3 3 2 Initiator tRNA phosphoribosyl transferase Mito_carr PF00153.22 EGO26330.1 - 1.6e-68 226.4 2.6 3.1e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FSH1 PF03959.8 EGO26331.1 - 5.3e-53 179.5 0.0 6.1e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGO26331.1 - 5.4e-05 23.1 0.4 0.26 11.1 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO26331.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO26331.1 - 0.097 12.0 0.0 0.97 8.8 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EGO26331.1 - 0.11 11.9 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 PE-PPE domain FSH1 PF03959.8 EGO26332.1 - 7.8e-35 120.2 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGO26332.1 - 0.0002 21.1 0.0 0.00051 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO26332.1 - 0.0057 16.5 0.0 0.0092 15.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGO26332.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1152 PF06626.7 EGO26333.1 - 0.051 12.6 0.0 0.052 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) HEAT_EZ PF13513.1 EGO26334.1 - 5.8e-23 80.7 21.2 5.7e-10 39.3 0.0 11.0 9 4 2 11 11 11 4 HEAT-like repeat HEAT PF02985.17 EGO26334.1 - 1.6e-21 74.4 15.1 0.00011 21.9 0.0 10.1 9 0 0 9 9 9 6 HEAT repeat HEAT_2 PF13646.1 EGO26334.1 - 6.1e-19 68.0 1.3 1.5e-05 25.1 0.0 6.8 4 4 1 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.2 EGO26334.1 - 3.3e-10 40.2 0.2 0.0068 16.7 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGO26334.1 - 3e-08 33.1 0.6 0.19 11.6 0.0 6.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EGO26334.1 - 3.7e-07 30.1 0.2 0.58 9.9 0.1 5.6 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGO26334.1 - 0.00037 18.9 0.5 0.51 8.5 0.0 3.4 4 0 0 4 4 4 2 Adaptin N terminal region Cohesin_HEAT PF12765.2 EGO26334.1 - 0.015 15.2 0.6 77 3.4 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Lectin_leg-like PF03388.8 EGO26335.1 - 1.3e-63 214.2 0.0 1.6e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGO26335.1 - 0.0032 16.8 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ER_lumen_recept PF00810.13 EGO26336.1 - 2.6e-59 199.9 10.2 3.5e-59 199.5 7.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGO26336.1 - 0.002 17.6 7.6 1.4 8.5 0.0 4.2 3 1 1 4 4 4 2 PQ loop repeat DnaJ PF00226.26 EGO26337.1 - 1.9e-12 46.7 0.0 3.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1858 PF08984.6 EGO26337.1 - 0.081 12.5 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) Homeobox_KN PF05920.6 EGO26338.1 - 0.0073 15.9 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGO26338.1 - 0.089 12.4 0.3 0.15 11.7 0.2 1.4 1 1 0 1 1 1 0 Homeobox domain Pkinase PF00069.20 EGO26339.1 - 8.7e-66 221.7 0.0 1e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26339.1 - 1.2e-35 122.8 0.0 1.6e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO26339.1 - 0.13 11.3 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF148 PF02520.12 EGO26340.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 SNF2_N PF00176.18 EGO26341.1 - 1.5e-69 234.1 1.1 1.9e-69 233.7 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO26341.1 - 3.1e-13 49.3 0.4 4.3e-12 45.7 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO26341.1 - 5.6e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO26341.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EGO26341.1 - 0.0034 16.2 0.0 0.88 8.3 0.0 2.4 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Pro-kuma_activ PF09286.6 EGO26342.1 - 1.4e-45 154.8 0.1 2.9e-45 153.8 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26342.1 - 7.8e-07 28.5 7.2 7.8e-07 28.5 5.0 2.5 2 1 0 2 2 2 1 Subtilase family cEGF PF12662.2 EGO26343.1 - 0.018 14.6 0.7 0.018 14.6 0.5 2.3 3 0 0 3 3 3 0 Complement Clr-like EGF-like Pro-kuma_activ PF09286.6 EGO26344.1 - 1.1e-45 155.2 0.1 2.9e-45 153.8 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26344.1 - 4.4e-05 22.7 1.2 8.1e-05 21.9 0.8 1.4 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 EGO26345.1 - 2.2e-47 160.7 0.5 5.1e-46 156.2 0.2 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Pro-kuma_activ PF09286.6 EGO26346.1 - 3.1e-42 144.0 0.1 4.5e-41 140.2 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26346.1 - 2.8e-05 23.4 3.3 8.1e-05 21.8 2.0 1.9 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 EGO26347.1 - 1.5e-43 148.2 0.1 1.3e-42 145.2 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26347.1 - 4.2e-06 26.1 1.0 9e-06 25.0 0.4 1.7 2 0 0 2 2 2 1 Subtilase family Sulfate_transp PF00916.15 EGO26348.1 - 6.7e-57 192.6 6.3 6.7e-57 192.6 4.4 1.9 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGO26348.1 - 4.1e-25 87.2 5.5 4.1e-25 87.2 3.8 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGO26348.1 - 3.2e-18 65.2 0.0 5.5e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGO26348.1 - 1.8e-06 27.9 0.0 3.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain Peptidase_S8 PF00082.17 EGO26349.1 - 1.3e-48 165.6 9.8 2e-48 164.9 6.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGO26349.1 - 4.7e-16 59.1 0.2 9e-16 58.2 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Kinesin PF00225.18 EGO26350.1 - 8.9e-41 139.6 0.1 1.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Pro-kuma_activ PF09286.6 EGO26351.1 - 1.3e-47 161.4 1.3 1.1e-46 158.4 0.3 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26351.1 - 0.00052 19.2 2.9 0.00084 18.5 1.3 1.9 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 EGO26352.1 - 3e-42 144.0 0.1 2.2e-41 141.2 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26352.1 - 3.6e-06 26.3 2.7 8.8e-06 25.0 1.9 1.6 1 0 0 1 1 1 1 Subtilase family zf-CCHC PF00098.18 EGO26354.1 - 1.5e-08 34.1 4.0 2.7e-08 33.3 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26354.1 - 4.7e-07 29.7 3.1 4.9e-07 29.7 0.1 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO26354.1 - 0.031 13.9 1.8 0.031 13.9 1.2 2.0 2 0 0 2 2 2 0 Zinc knuckle Herpes_UL55 PF04537.7 EGO26354.1 - 0.062 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein Pro-kuma_activ PF09286.6 EGO26355.1 - 5.5e-43 146.4 0.1 4e-42 143.6 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO26355.1 - 4.6e-07 29.2 2.4 1.3e-06 27.8 1.7 1.7 1 0 0 1 1 1 1 Subtilase family Granulin PF00396.13 EGO26356.1 - 0.88 9.7 26.5 2.1 8.4 1.0 3.0 1 1 1 2 2 2 0 Granulin 3HCDH_N PF02737.13 EGO26359.1 - 6.4e-52 175.8 3.2 3.8e-51 173.2 2.2 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGO26359.1 - 2.4e-32 111.1 0.0 5.7e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGO26359.1 - 0.00017 21.4 1.4 0.00075 19.3 0.6 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGO26359.1 - 0.00026 20.7 0.1 0.00046 19.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EGO26359.1 - 0.093 13.1 4.4 0.91 9.9 1.7 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Cyclase PF04199.8 EGO26360.1 - 3.3e-33 114.7 0.4 4.2e-33 114.4 0.2 1.1 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_31 PF01055.21 EGO26362.1 - 1.6e-142 475.4 5.7 1.7e-142 475.3 2.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO26362.1 - 5.7e-17 61.3 0.0 1.4e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like Gb3_synth PF04572.7 EGO26362.1 - 0.0071 16.0 0.1 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Sin_N PF04801.8 EGO26363.1 - 1.9e-22 79.6 0.0 2.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Abhydrolase_3 PF07859.8 EGO26364.1 - 3.3e-22 79.1 0.0 5.1e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO26364.1 - 8.2e-06 24.6 0.0 1.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) FcoT PF10862.3 EGO26365.1 - 0.12 11.9 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain DUF1602 PF07673.9 EGO26369.1 - 0.42 10.1 0.2 0.42 10.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1602) polyprenyl_synt PF00348.12 EGO26372.1 - 1.3e-46 158.5 0.0 6.5e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Leu_leader PF08054.6 EGO26372.1 - 8.9 6.0 7.0 7.7 6.2 0.2 2.9 3 0 0 3 3 3 0 Leucine operon leader peptide DUF2361 PF10153.4 EGO26373.1 - 2.5e-10 40.5 2.6 2.5e-10 40.5 1.8 1.6 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2361) LytTR PF04397.10 EGO26373.1 - 0.024 14.7 0.1 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 LytTr DNA-binding domain ATP-synt_D PF01813.12 EGO26373.1 - 0.068 12.7 8.5 0.074 12.6 5.9 1.1 1 0 0 1 1 1 0 ATP synthase subunit D IKI3 PF04762.7 EGO26374.1 - 3.8e-230 766.3 0.4 3.5e-127 425.5 0.0 3.2 1 1 0 2 2 2 2 IKI3 family Med11 PF10280.4 EGO26374.1 - 0.022 14.7 1.0 0.16 12.0 0.1 2.5 2 0 0 2 2 2 0 Mediator complex protein DUF460 PF04312.8 EGO26374.1 - 0.031 13.8 0.0 2.2 7.8 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF460) Shisa PF13908.1 EGO26375.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MIF4G PF02854.14 EGO26376.1 - 6e-39 133.6 0.0 9.7e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EGO26376.1 - 4.2e-07 29.6 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 MA3 domain DUF572 PF04502.8 EGO26376.1 - 0.0037 16.5 1.0 0.01 15.0 0.7 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF3484 PF11983.3 EGO26376.1 - 0.6 10.9 4.3 0.17 12.7 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) TrkH PF02386.11 EGO26377.1 - 4.3e-88 295.2 14.7 1.5e-86 290.1 5.6 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.6 EGO26377.1 - 0.13 11.9 1.8 0.24 11.0 0.2 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein LCM PF04072.9 EGO26380.1 - 7.1e-24 84.3 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase FMN_dh PF01070.13 EGO26382.1 - 1.8e-120 402.0 0.0 2.2e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGO26382.1 - 1e-21 76.4 0.0 2.7e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGO26382.1 - 1.8e-05 23.8 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGO26382.1 - 2.8e-05 23.2 0.1 5.7e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EGO26382.1 - 0.0042 16.2 0.5 0.34 9.9 0.1 2.3 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EGO26382.1 - 0.026 13.6 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 EGO26382.1 - 0.028 13.6 0.0 0.076 12.2 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 EGO26382.1 - 0.12 11.2 0.2 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PEP_mutase PF13714.1 EGO26383.1 - 9e-48 162.5 2.0 1.1e-47 162.2 1.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EGO26383.1 - 2.7e-18 65.4 0.4 3.8e-18 65.0 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family FMN_dh PF01070.13 EGO26384.1 - 3.5e-119 397.8 0.1 4.2e-119 397.5 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGO26384.1 - 1.4e-20 72.9 0.0 3.3e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGO26384.1 - 4.7e-05 22.4 0.0 7.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGO26384.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain RVP_2 PF08284.6 EGO26385.1 - 0.055 13.4 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Imm_superinfect PF14373.1 EGO26385.1 - 0.1 12.2 0.2 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Superinfection immunity protein Retrotrans_gag PF03732.12 EGO26386.1 - 5.3e-08 32.8 0.5 2.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Herpes_UL32 PF06070.6 EGO26386.1 - 0.021 13.3 0.5 0.1 11.0 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 BMFP PF04380.8 EGO26386.1 - 0.092 12.8 0.6 1 9.5 0.3 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity gag-asp_proteas PF13975.1 EGO26387.1 - 5.1e-09 35.8 0.0 7.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO26387.1 - 2.2e-06 27.6 0.0 2.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO26387.1 - 0.00016 22.1 0.0 0.00031 21.1 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO26387.1 - 0.086 12.4 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease PAM2 PF07145.10 EGO26389.1 - 0.022 14.2 0.3 5.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Ataxin-2 C-terminal region CDK5_activator PF03261.10 EGO26389.1 - 0.099 11.9 7.6 0.15 11.4 5.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF896 PF05979.7 EGO26389.1 - 3.3 7.3 13.4 0.043 13.4 2.2 2.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF896) eIF_4G1 PF12152.3 EGO26390.1 - 1.9e-16 59.6 0.1 3.3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 SBP56 PF05694.6 EGO26390.1 - 0.087 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) MIF4G PF02854.14 EGO26391.1 - 6.7e-34 117.1 0.0 1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EGO26391.1 - 2.9e-06 26.9 0.0 8.1e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 MA3 domain DUF3484 PF11983.3 EGO26391.1 - 0.016 16.0 0.5 0.05 14.4 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) Costars PF14705.1 EGO26391.1 - 0.046 13.7 0.1 25 4.9 0.0 3.3 3 0 0 3 3 3 0 Costars DUF572 PF04502.8 EGO26391.1 - 0.24 10.6 4.3 0.068 12.3 0.6 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF572) Hydrophobin PF01185.13 EGO26392.1 - 7.8e-15 55.0 12.0 9.6e-15 54.8 8.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 EGO26392.1 - 2 8.9 7.4 8.6 6.9 0.2 2.7 4 0 0 4 4 4 0 Ion channel inhibitory toxin MIF4G PF02854.14 EGO26393.1 - 1.8e-89 298.6 11.2 1.9e-50 171.1 0.3 2.4 2 0 0 2 2 2 2 MIF4G domain eIF_4G1 PF12152.3 EGO26393.1 - 4.7e-13 48.8 0.1 1.3e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EGO26393.1 - 5.4e-07 29.3 1.1 6e-06 25.9 0.0 3.2 4 0 0 4 4 4 1 MA3 domain DUF4041 PF13250.1 EGO26393.1 - 0.057 12.9 1.4 9.2 5.9 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) HSP70 PF00012.15 EGO26396.1 - 2e-265 881.4 13.5 2.3e-265 881.2 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO26396.1 - 1.4e-15 56.7 4.4 4.7e-14 51.7 0.5 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 EGO26396.1 - 8.4e-05 22.3 6.2 0.86 9.4 0.0 4.6 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 EGO26396.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain WD40 PF00400.27 EGO26397.1 - 3.3e-10 39.4 7.7 6.9e-07 28.9 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat APH PF01636.18 EGO26399.1 - 1.1e-39 136.6 0.0 1.6e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO26399.1 - 3.3e-09 36.6 0.0 5.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGO26399.1 - 8.8e-07 28.3 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EGO26399.1 - 0.051 12.7 0.0 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EGO26399.1 - 0.19 10.3 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 EGO26400.1 - 4.2e-45 153.9 0.0 5.6e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26400.1 - 7.1e-45 153.0 0.0 9.3e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO26400.1 - 7.3e-06 25.1 0.0 1.5e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGO26400.1 - 0.031 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Na_H_antiport_1 PF06965.7 EGO26400.1 - 0.15 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Abhydrolase_3 PF07859.8 EGO26401.1 - 5.6e-21 75.0 0.5 1.7e-15 57.1 0.4 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO26401.1 - 0.0018 16.9 0.0 0.095 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO26401.1 - 0.028 14.1 0.0 0.086 12.5 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family GST_N_3 PF13417.1 EGO26403.1 - 4.1e-22 78.1 0.0 7.7e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO26403.1 - 1.9e-14 53.3 0.0 3.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO26403.1 - 1.6e-06 27.9 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO26403.1 - 2.7e-06 27.4 0.0 6.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO26403.1 - 6.4e-06 25.9 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO26403.1 - 0.0062 17.0 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.20 EGO26404.1 - 9.5e-20 71.1 1.2 2.6e-19 69.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO26404.1 - 4.7e-08 32.9 0.1 7.4e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EGO26404.1 - 0.015 15.4 0.2 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EGO26404.1 - 0.018 13.9 0.2 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Gryzun PF07919.7 EGO26405.1 - 2.3e-53 181.3 0.0 3.3e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EGO26405.1 - 4.3e-51 173.7 1.2 2.5e-50 171.2 0.4 2.3 2 1 0 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 EGO26405.1 - 4.5e-05 23.3 2.5 0.0033 17.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TRAPPC10 PF12584.3 EGO26405.1 - 0.00039 19.9 0.0 0.00085 18.8 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Transglut_C PF00927.17 EGO26405.1 - 0.034 14.1 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain TPR_1 PF00515.23 EGO26405.1 - 0.058 13.0 1.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26405.1 - 0.13 12.2 4.5 0.18 11.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO26405.1 - 0.17 12.3 0.5 0.77 10.3 0.3 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26405.1 - 0.26 11.1 1.0 1.1 9.1 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat FAP PF07174.6 EGO26407.1 - 0.22 10.7 6.5 0.26 10.5 4.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ubiquitin PF00240.18 EGO26409.1 - 2.6e-07 29.9 0.5 1.1e-06 27.9 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGO26409.1 - 4e-06 26.9 0.1 1.5e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain PI3K_rbd PF00794.13 EGO26409.1 - 0.0039 17.0 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain Rad60-SLD PF11976.3 EGO26409.1 - 0.0089 15.6 0.1 0.035 13.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EGO26409.1 - 0.033 14.4 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF3604 PF12228.3 EGO26411.1 - 0.06 11.4 1.4 0.066 11.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) GWT1 PF06423.7 EGO26412.1 - 3.4 7.7 11.7 0.21 11.6 3.6 2.4 2 1 1 3 3 3 0 GWT1 DUF2156 PF09924.4 EGO26414.1 - 1.9e-13 49.9 0.0 1.6e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2156) Acetyltransf_10 PF13673.1 EGO26414.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L37 PF08561.5 EGO26414.1 - 0.077 12.5 0.4 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 WRKY PF03106.10 EGO26416.1 - 0.42 10.4 1.8 2.6 7.9 0.0 2.1 1 1 1 2 2 2 0 WRKY DNA -binding domain PROCN PF08083.6 EGO26417.1 - 0.066 11.6 1.4 0.081 11.3 1.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Herpes_UL6 PF01763.11 EGO26417.1 - 0.12 10.5 1.3 0.15 10.2 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Atg14 PF10186.4 EGO26417.1 - 0.38 9.6 7.3 0.49 9.2 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ABC_membrane PF00664.18 EGO26419.1 - 3.3e-43 148.0 0.4 5.5e-43 147.3 0.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGO26419.1 - 4.2e-30 104.8 0.0 1.2e-29 103.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGO26419.1 - 1.1e-05 24.7 0.1 0.00081 18.6 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO26419.1 - 0.00073 19.5 0.0 0.078 12.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EGO26419.1 - 0.012 15.0 0.2 3 7.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EGO26419.1 - 0.026 13.6 0.0 0.072 12.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EGO26419.1 - 0.031 14.2 1.7 0.22 11.4 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGO26419.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PGP_phosphatase PF09419.5 EGO26420.1 - 6.3e-15 54.9 0.0 6.4e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Clathrin_lg_ch PF01086.12 EGO26421.1 - 1.4e-41 142.8 4.1 1.6e-40 139.4 2.8 2.0 1 1 0 1 1 1 1 Clathrin light chain Ribosomal_L30_N PF08079.7 EGO26421.1 - 2.1 8.4 9.8 3.7 7.6 6.8 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Abhydrolase_6 PF12697.2 EGO26422.1 - 4.1e-23 82.4 0.1 4.9e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO26422.1 - 9.9e-19 66.9 0.1 1.8e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EGO26422.1 - 1.1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO26422.1 - 0.0024 17.1 1.1 0.11 11.7 0.0 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGO26422.1 - 0.0086 15.5 0.4 0.21 10.9 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EGO26422.1 - 0.03 13.8 0.4 0.37 10.3 0.4 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EGO26422.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EGO26422.1 - 0.084 11.3 0.0 0.76 8.2 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Glyco_hydro_28 PF00295.12 EGO26424.1 - 5.3e-58 196.5 9.6 7.3e-58 196.0 6.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RPA_interact_M PF14767.1 EGO26426.1 - 0.036 14.8 0.7 0.061 14.0 0.2 1.6 2 0 0 2 2 2 0 Replication protein A interacting middle DUF4072 PF13284.1 EGO26426.1 - 0.069 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Atg14 PF10186.4 EGO26426.1 - 0.12 11.3 0.1 0.12 11.3 0.1 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EGO26426.1 - 1.2 8.6 3.7 0.59 9.6 0.2 2.0 2 0 0 2 2 2 0 Septum formation initiator BTB PF00651.26 EGO26427.1 - 4.4e-09 36.2 0.0 1e-08 35.1 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EGO26428.1 - 7.5e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EGO26429.1 - 1.4e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.4 EGO26430.1 - 1.2e-34 119.4 0.1 1.7e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BTB PF00651.26 EGO26431.1 - 4.3e-09 36.3 0.0 6.9e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EGO26432.1 - 4.3e-05 23.4 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SinI PF08671.5 EGO26432.1 - 0.12 11.7 0.3 0.12 11.7 0.2 2.1 2 0 0 2 2 2 0 Anti-repressor SinI BTB PF00651.26 EGO26433.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SUR7 PF06687.7 EGO26437.1 - 2.1e-05 24.1 11.0 0.0002 20.9 7.0 2.2 1 1 0 1 1 1 1 SUR7/PalI family Flavi_capsid PF01003.14 EGO26437.1 - 0.077 12.5 0.8 0.11 12.0 0.6 1.2 1 0 0 1 1 1 0 Flavivirus capsid protein C Phage_holin_1 PF04531.8 EGO26437.1 - 0.13 12.3 0.8 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage holin Claudin_2 PF13903.1 EGO26437.1 - 2.1 7.9 7.5 1.8 8.2 4.5 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction BCLP PF12304.3 EGO26437.1 - 4.9 6.5 7.5 12 5.2 0.9 2.4 2 1 0 2 2 2 0 Beta-casein like protein RNase_T PF00929.19 EGO26440.1 - 2.2e-21 76.8 0.0 3.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGO26440.1 - 0.0035 16.8 0.0 0.0074 15.7 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease Mito_carr PF00153.22 EGO26441.1 - 1.7e-44 149.4 2.6 1.1e-18 66.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 EGO26441.1 - 0.0066 16.2 1.0 1.5 8.6 0.1 2.3 2 0 0 2 2 2 2 Colicin V production protein HSP70 PF00012.15 EGO26442.1 - 0.0068 14.3 0.1 1.1 7.0 0.0 3.2 2 2 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EGO26442.1 - 0.016 13.7 0.2 4.7 5.7 0.0 2.5 2 0 0 2 2 2 0 MreB/Mbl protein Hydantoinase_A PF01968.13 EGO26442.1 - 0.023 13.8 0.1 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EGO26442.1 - 0.059 12.9 0.0 3.3 7.2 0.0 3.2 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain KR PF08659.5 EGO26443.1 - 7.6e-06 25.7 0.0 2e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGO26443.1 - 3e-05 23.9 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Cpn60_TCP1 PF00118.19 EGO26444.1 - 1.3e-132 442.9 0.3 1.4e-132 442.7 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Alpha_L_fucos PF01120.12 EGO26449.1 - 6.5e-81 271.9 2.2 7.5e-81 271.7 1.5 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase FYVE PF01363.16 EGO26450.1 - 0.018 14.9 0.4 0.043 13.7 0.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF3141 PF11339.3 EGO26451.1 - 0.47 8.7 1.6 0.5 8.6 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DDE_Tnp_4 PF13359.1 EGO26454.1 - 3e-29 101.6 0.0 3.9e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RabGAP-TBC PF00566.13 EGO26454.1 - 0.021 14.3 0.6 0.035 13.5 0.4 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Plant_tran PF04827.9 EGO26454.1 - 0.034 13.5 0.4 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Plant transposon protein WD40 PF00400.27 EGO26456.1 - 1.5e-13 50.0 10.7 1e-05 25.2 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO26456.1 - 0.00073 19.2 0.0 0.17 11.5 0.0 3.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EGO26456.1 - 0.08 12.2 0.0 3.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF1903 PF08991.5 EGO26457.1 - 3.9e-15 55.7 6.2 5.1e-15 55.3 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) DUF4656 PF15551.1 EGO26457.1 - 0.38 9.8 3.8 0.41 9.7 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) Ribosomal_L22e PF01776.12 EGO26458.1 - 2.3e-48 162.8 0.7 2.6e-48 162.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2660 PF10859.3 EGO26458.1 - 0.1 12.8 0.2 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) polyprenyl_synt PF00348.12 EGO26462.1 - 2.6e-49 167.4 0.0 6.9e-49 166.0 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase DUF2542 PF10808.3 EGO26463.1 - 0.069 13.4 1.1 0.069 13.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) DUF3611 PF12263.3 EGO26463.1 - 0.076 12.4 2.4 0.089 12.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) DUF2628 PF10947.3 EGO26463.1 - 6.9 6.5 10.3 6.5 6.6 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) ubiquitin PF00240.18 EGO26464.1 - 2.4e-171 555.4 28.5 7.6e-34 114.9 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 EGO26464.1 - 1.4e-96 316.2 28.1 8.4e-19 67.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO26464.1 - 8.7e-30 102.8 13.7 0.00025 21.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGO26464.1 - 3.3e-26 91.9 1.5 0.002 17.8 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGO26464.1 - 5.1e-17 61.7 5.3 0.16 11.8 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO26464.1 - 1e-16 60.8 3.3 0.22 11.7 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGO26464.1 - 2.8e-13 49.7 0.0 2 8.4 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EGO26464.1 - 8.2e-09 34.9 1.9 1.5 7.9 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase FlgD_ig PF13860.1 EGO26464.1 - 1.1e-08 34.6 8.0 4.6 7.0 0.0 5.3 5 0 0 5 5 5 5 FlgD Ig-like domain TUG-UBL1 PF11470.3 EGO26464.1 - 4.3e-07 29.7 7.9 9 6.3 0.0 5.2 5 0 0 5 5 5 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 EGO26464.1 - 6.4e-05 23.2 1.2 99 3.3 0.0 5.1 5 0 0 5 5 5 0 ACT domain Big_3_3 PF13750.1 EGO26464.1 - 0.00019 20.9 0.0 69 2.8 0.0 4.8 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EGO26464.1 - 0.0037 15.6 18.4 5.4 5.1 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 EGO26464.1 - 0.017 15.0 19.3 12 5.9 0.2 5.6 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 EGO26464.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.3 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 EGO26464.1 - 0.073 13.0 10.8 75 3.4 0.1 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain DUF3781 PF12636.2 EGO26464.1 - 5 7.1 10.4 2.2e+02 1.8 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EGO26464.1 - 7.6 6.6 17.8 1.2e+02 2.8 0.1 6.9 5 5 0 5 5 5 0 FERM N-terminal domain CDC48_2 PF02933.12 EGO26464.1 - 9.1 6.0 19.2 58 3.4 0.1 5.1 5 0 0 5 5 5 0 Cell division protein 48 (CDC48), domain 2 FA_desaturase PF00487.19 EGO26465.1 - 0.017 14.5 0.9 0.017 14.5 0.6 1.0 1 0 0 1 1 1 0 Fatty acid desaturase DUF2975 PF11188.3 EGO26466.1 - 0.014 15.1 6.9 0.014 15.1 4.8 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) UPF0029 PF01205.14 EGO26467.1 - 2.4e-18 65.8 0.1 6.9e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF2365 PF10157.4 EGO26467.1 - 0.07 13.0 0.5 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF4398 PF14346.1 EGO26468.1 - 0.13 12.3 12.9 0.7 9.9 4.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) NARP1 PF12569.3 EGO26468.1 - 5.4 5.6 19.1 0.92 8.1 2.9 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DDA1 PF10172.4 EGO26469.1 - 0.0003 20.5 19.3 1.1e+02 2.7 0.0 10.2 11 0 0 11 11 11 0 Det1 complexing ubiquitin ligase KCl_Cotrans_1 PF03522.10 EGO26469.1 - 4.5 6.8 28.2 8.3 6.0 0.0 9.1 11 0 0 11 11 11 0 K-Cl Co-transporter type 1 (KCC1) FLILHELTA PF10306.4 EGO26470.1 - 2.1e-09 37.3 0.0 4.1e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EGO26470.1 - 0.0018 18.5 0.0 0.0028 17.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Acyl-CoA_dh_N PF02771.11 EGO26472.1 - 1.6e-25 89.8 0.0 2.9e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EGO26472.1 - 8.5e-24 84.3 0.2 1.3e-23 83.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO26472.1 - 1.3e-21 75.7 0.2 1.4e-20 72.5 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO26472.1 - 1.3e-05 25.4 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_B_palm PF14792.1 EGO26473.1 - 4.8e-20 71.7 0.0 2.1e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 EGO26473.1 - 4.3e-12 46.0 0.2 7.1e-10 38.9 0.1 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EGO26473.1 - 5.2e-10 38.7 0.0 1.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EGO26473.1 - 9.6e-07 28.8 0.0 5.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EGO26473.1 - 4.6e-06 26.2 0.0 1.5e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb Cdd1 PF11731.3 EGO26473.1 - 0.00065 19.5 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Pathogenicity locus NTP_transf_2 PF01909.18 EGO26473.1 - 0.0048 17.2 0.0 0.019 15.2 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain IMS_HHH PF11798.3 EGO26473.1 - 0.01 15.8 0.0 0.57 10.3 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif bZIP_1 PF00170.16 EGO26474.1 - 7.6e-08 32.2 8.9 7.6e-08 32.2 6.2 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGO26474.1 - 4e-07 29.7 8.9 4e-07 29.7 6.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper CENP-F_leu_zip PF10473.4 EGO26474.1 - 0.031 14.1 5.7 0.045 13.6 4.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EGO26474.1 - 0.7 9.9 4.0 1.2 9.1 2.8 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EGO26474.1 - 0.97 7.7 1.9 1.4 7.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EGO26474.1 - 1.4 8.4 8.7 2.9 7.4 6.0 1.4 1 0 0 1 1 1 0 IncA protein DUF641 PF04859.7 EGO26474.1 - 2.2 8.0 6.6 5.1 6.8 0.5 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CTP_transf_2 PF01467.21 EGO26475.1 - 1.2e-23 83.8 0.0 1.5e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Amidase PF01425.16 EGO26476.1 - 8.5e-77 258.8 0.0 1.1e-76 258.5 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF221 PF02714.10 EGO26478.1 - 2.1e-88 296.3 21.2 3.9e-88 295.4 14.7 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO26478.1 - 9.1e-38 129.2 0.9 9.1e-38 129.2 0.6 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGO26478.1 - 2.6e-11 43.8 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Imm42 PF15601.1 EGO26479.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 42 Pkinase PF00069.20 EGO26481.1 - 6.6e-07 28.7 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26481.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3809 PF12723.2 EGO26481.1 - 0.051 13.4 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) GH114_assoc PF14741.1 EGO26482.1 - 1.6 8.4 5.2 7.4 6.3 0.5 2.8 3 0 0 3 3 3 0 N-terminal glycosyl-hydrolase-114-associated domain ThiF PF00899.16 EGO26483.1 - 4.6e-31 107.4 0.0 7.7e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EGO26483.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FGE-sulfatase PF03781.11 EGO26484.1 - 2.1e-23 83.0 0.3 2.5e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGO26484.1 - 1.1e-07 32.2 1.5 2e-07 31.3 1.0 1.4 1 0 0 1 1 1 1 DinB superfamily eRF1_1 PF03463.10 EGO26484.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 TatD_DNase PF01026.16 EGO26488.1 - 2.1e-25 89.3 0.0 2.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Met_10 PF02475.11 EGO26489.1 - 3.9e-64 215.9 0.0 7.1e-64 215.0 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EGO26489.1 - 1.2e-06 28.5 0.0 2.2e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO26489.1 - 0.00022 21.7 0.0 0.00094 19.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGO26489.1 - 0.027 13.8 0.0 0.082 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.5 EGO26489.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.10 EGO26489.1 - 0.038 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Pyridoxal_deC PF00282.14 EGO26490.1 - 6.9e-115 383.4 0.0 8e-115 383.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain adh_short PF00106.20 EGO26491.1 - 5.4e-20 71.9 0.0 7.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO26491.1 - 2.7e-06 27.1 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGO26491.1 - 9e-06 25.0 0.1 1.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 EGO26491.1 - 0.00016 21.5 0.1 0.0004 20.2 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO26491.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Tropomyosin PF00261.15 EGO26492.1 - 0.67 8.9 29.9 1.3 8.0 18.1 3.5 2 1 0 2 2 2 0 Tropomyosin GAS PF13851.1 EGO26492.1 - 1.2 8.2 23.7 0.12 11.5 9.2 3.2 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.1 EGO26492.1 - 2.4 7.2 20.8 1.2 8.1 11.3 2.4 1 1 1 2 2 2 0 TMCO5 family DAO PF01266.19 EGO26493.1 - 5.7e-31 107.7 0.0 6.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO26493.1 - 0.0019 18.2 0.0 0.094 12.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO26493.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.2 EGO26494.1 - 1.2e-10 40.9 0.9 3.4e-10 39.4 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO26494.1 - 0.01 15.4 0.2 0.037 13.6 0.1 2.1 2 0 0 2 2 2 0 F-box domain Pex2_Pex12 PF04757.9 EGO26495.1 - 0.077 12.3 0.2 4 6.8 0.1 2.1 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region zf-CCHC PF00098.18 EGO26497.1 - 1.8e-08 33.9 1.5 3.6e-08 32.9 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26497.1 - 2.5e-06 27.4 0.7 1.6e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EGO26497.1 - 0.32 10.6 1.4 0.61 9.8 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO26497.1 - 0.37 10.5 3.0 0.81 9.4 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF563 PF04577.9 EGO26499.1 - 3.6e-21 76.0 0.1 8.5e-21 74.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) LCAT PF02450.10 EGO26500.1 - 3.1e-57 194.3 0.9 4.1e-29 101.7 0.3 2.9 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EGO26500.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EGO26500.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Trp_halogenase PF04820.9 EGO26501.1 - 9.5e-27 93.7 2.0 2.3e-15 56.2 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase FAD_binding_3 PF01494.14 EGO26501.1 - 1.8e-09 37.1 0.3 5.7e-08 32.2 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGO26501.1 - 6.7e-07 28.5 1.9 0.00033 19.6 0.5 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO26501.1 - 2.8e-05 24.1 0.1 5.4e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO26501.1 - 3.1e-05 23.2 2.9 0.00013 21.2 2.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO26501.1 - 4.1e-05 22.7 0.9 0.0011 18.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 EGO26501.1 - 6.5e-05 22.8 0.7 0.00018 21.4 0.2 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO26501.1 - 0.00014 20.4 0.3 0.00025 19.6 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EGO26501.1 - 0.00027 19.9 0.1 0.00044 19.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGO26501.1 - 0.00047 19.1 0.5 0.00089 18.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGO26501.1 - 0.0019 18.2 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO26501.1 - 0.0041 17.5 0.1 0.0094 16.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO26501.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 EGO26501.1 - 0.11 12.2 0.4 0.41 10.4 0.5 1.8 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.13 EGO26501.1 - 0.12 11.9 0.2 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EGO26503.1 - 3.8e-68 229.4 0.0 4.7e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26503.1 - 3e-29 101.8 0.0 4e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO26503.1 - 0.013 15.2 0.2 0.042 13.5 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO26503.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO26503.1 - 0.077 11.9 0.0 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Fic PF02661.13 EGO26504.1 - 8.2e-11 42.4 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Fic/DOC family IGPS PF00218.16 EGO26506.1 - 5.8e-93 310.5 0.0 1.2e-92 309.5 0.0 1.6 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGO26506.1 - 1.2e-53 181.6 0.0 9.4e-50 168.9 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EGO26506.1 - 2.7e-47 160.7 0.0 8.7e-47 159.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO26506.1 - 3.7e-05 23.2 0.1 9.9e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.9 EGO26506.1 - 0.0006 18.8 0.1 0.013 14.4 0.0 2.7 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.14 EGO26506.1 - 0.0016 17.9 0.4 0.01 15.3 0.1 2.4 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EGO26506.1 - 0.013 14.8 0.0 0.031 13.5 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 EGO26506.1 - 0.059 12.4 0.0 0.059 12.4 0.0 2.4 4 0 0 4 4 4 0 Thiazole biosynthesis protein ThiG PB1 PF00564.19 EGO26507.1 - 4.3e-14 51.9 0.0 9.3e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 EGO26507.1 - 3.1e-12 45.9 1.5 1.7e-06 27.5 0.0 3.4 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 EGO26507.1 - 1.8e-07 30.5 0.9 0.099 12.6 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26507.1 - 2.2e-07 30.1 3.1 0.036 13.7 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO26507.1 - 3.5e-05 23.6 0.6 0.0035 17.2 0.1 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO26507.1 - 0.00021 20.8 4.8 0.042 13.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO26507.1 - 0.039 14.1 0.1 0.63 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26507.1 - 0.15 11.8 3.2 2.6 8.0 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat G-patch PF01585.18 EGO26508.1 - 2.6e-06 27.1 0.1 2.6e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EGO26508.1 - 0.0018 18.0 0.2 0.0018 18.0 0.1 2.2 2 1 0 2 2 2 1 DExH-box splicing factor binding site Abhydro_lipase PF04083.11 EGO26509.1 - 1.5e-21 75.4 0.1 2.9e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EGO26509.1 - 1.1e-17 64.4 0.3 1.5e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO26509.1 - 1.9e-08 34.4 0.0 3.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO26509.1 - 0.00071 19.3 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGO26509.1 - 0.0013 18.2 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) DUF2635 PF10948.3 EGO26510.1 - 0.1 11.9 0.3 0.2 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) zf-C2H2 PF00096.21 EGO26511.1 - 7.2e-17 60.6 81.4 0.014 15.7 1.4 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO26511.1 - 2.1e-13 49.8 69.5 4.4e-06 26.7 0.3 11.4 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO26511.1 - 7.9e-09 35.2 82.8 0.012 15.9 1.1 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.2 EGO26511.1 - 0.0038 17.3 1.5 0.0038 17.3 1.0 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-tcix PF14952.1 EGO26511.1 - 0.026 13.8 1.9 4.9 6.5 0.2 3.3 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding Mut7-C PF01927.11 EGO26511.1 - 0.056 13.4 2.2 0.19 11.6 1.5 1.9 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-C2H2_jaz PF12171.3 EGO26511.1 - 0.17 12.0 0.3 0.17 12.0 0.2 7.7 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EGO26511.1 - 4.3 7.0 13.9 3.5 7.2 0.0 4.4 3 1 1 4 4 4 0 GAGA factor Isochorismatase PF00857.15 EGO26512.1 - 2e-18 66.9 0.3 2.5e-13 50.3 0.1 2.0 2 0 0 2 2 2 2 Isochorismatase family PH PF00169.24 EGO26514.1 - 2.9e-06 27.4 0.0 6.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Anillin PF08174.6 EGO26514.1 - 3.8e-06 26.9 0.0 8.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin FOLN PF09289.5 EGO26514.1 - 0.22 11.4 0.2 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain STE3 PF02076.10 EGO26515.1 - 0.0012 18.0 1.4 0.0015 17.6 1.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EGO26516.1 - 7e-63 212.3 25.0 8.2e-63 212.1 17.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor PHO4 PF01384.15 EGO26516.1 - 0.032 12.8 0.2 0.032 12.8 0.1 2.4 3 1 0 3 3 3 0 Phosphate transporter family Peptidase_M24 PF00557.19 EGO26517.1 - 5.3e-44 150.2 0.0 6.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGO26517.1 - 0.00019 21.2 3.5 0.0005 19.8 2.4 1.7 1 0 0 1 1 1 1 MYND finger STE3 PF02076.10 EGO26518.1 - 4.4e-69 232.7 14.7 5.3e-69 232.4 10.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor Virul_fac_BrkB PF03631.10 EGO26518.1 - 4.4 6.5 13.2 0.19 11.0 0.2 2.5 3 0 0 3 3 3 0 Virulence factor BrkB ubiquitin PF00240.18 EGO26519.1 - 9.8e-138 447.7 21.2 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EGO26519.1 - 6.7e-78 256.3 20.9 5.8e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO26519.1 - 1.6e-24 85.9 9.4 0.00017 21.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGO26519.1 - 2.4e-21 76.0 0.6 0.0014 18.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGO26519.1 - 3.7e-14 52.5 2.9 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO26519.1 - 1.1e-13 51.2 1.7 0.15 12.2 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGO26519.1 - 1.1e-10 41.3 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EGO26519.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EGO26519.1 - 8.7e-07 28.2 0.6 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EGO26519.1 - 3.1e-06 27.0 4.8 6.4 6.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG ACT_4 PF13291.1 EGO26519.1 - 0.00081 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 EGO26519.1 - 0.0014 18.0 0.0 50 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EGO26519.1 - 0.0033 15.8 13.1 3.9 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EGO26519.1 - 0.012 15.6 5.3 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EGO26519.1 - 0.022 14.6 13.9 8.8 6.3 0.2 4.6 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EGO26519.1 - 0.027 14.4 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EGO26519.1 - 0.045 13.7 7.0 53 3.9 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EGO26519.1 - 1.4 9.0 12.6 86 3.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain CDC48_2 PF02933.12 EGO26519.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 DUF3781 PF12636.2 EGO26519.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) RFC1 PF08519.7 EGO26526.1 - 0.079 12.7 0.1 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Mucin PF01456.12 EGO26527.1 - 6 6.6 12.3 6.3 6.5 8.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltransf_2 PF00891.13 EGO26529.1 - 1.6e-32 112.6 0.0 2.7e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGO26529.1 - 0.00062 19.5 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO26529.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGO26529.1 - 0.0047 17.5 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO26529.1 - 0.019 14.5 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO26529.1 - 0.029 14.8 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EGO26529.1 - 0.062 12.4 0.1 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Met_10 PF02475.11 EGO26529.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein NACHT PF05729.7 EGO26530.1 - 4.6e-07 29.6 0.1 1.3e-06 28.1 0.0 1.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EGO26530.1 - 6.2e-07 29.5 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO26530.1 - 8.3e-07 29.2 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO26530.1 - 6.1e-05 23.8 0.1 0.002 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGO26530.1 - 0.00011 21.2 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 EGO26530.1 - 0.00037 19.9 0.0 0.00069 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO26530.1 - 0.0014 17.6 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EGO26530.1 - 0.0035 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EGO26530.1 - 0.01 16.0 0.0 0.034 14.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGO26530.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 1 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EGO26530.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EGO26530.1 - 0.034 14.4 0.0 0.087 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGO26530.1 - 0.049 12.7 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EGO26530.1 - 0.066 12.6 0.1 0.41 10.0 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EGO26530.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EGO26530.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EGO26530.1 - 0.08 12.3 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AA_permease_N PF08403.5 EGO26530.1 - 0.085 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal APS_kinase PF01583.15 EGO26530.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Ank_2 PF12796.2 EGO26531.1 - 1.5e-15 57.2 0.4 3.5e-10 40.0 0.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO26531.1 - 1.3e-13 50.7 4.0 3.1e-09 36.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO26531.1 - 4.4e-11 41.9 3.8 2.8e-06 26.8 0.3 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGO26531.1 - 8.7e-10 38.8 2.2 5.1e-06 26.8 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO26531.1 - 3.1e-07 30.0 1.6 0.00061 19.7 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat PHD_2 PF13831.1 EGO26534.1 - 0.32 10.3 5.1 0.52 9.6 0.8 2.5 2 0 0 2 2 2 0 PHD-finger HAUS-augmin3 PF14932.1 EGO26535.1 - 0.015 14.4 1.4 0.014 14.5 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Phage_int_SAM_5 PF13102.1 EGO26535.1 - 0.085 12.8 0.5 0.36 10.8 0.0 1.8 1 1 1 2 2 2 0 Phage integrase SAM-like domain Retrotrans_gag PF03732.12 EGO26536.1 - 9.5e-09 35.2 0.4 9.5e-09 35.2 0.3 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO26536.1 - 0.00077 19.2 9.1 0.0014 18.4 6.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO26536.1 - 2.5 7.9 8.6 1 9.1 3.7 2.0 2 0 0 2 2 2 0 Zinc knuckle ICE2 PF08426.5 EGO26538.1 - 7.4e-22 77.5 24.0 2.7e-12 46.0 6.4 3.0 1 1 1 3 3 3 3 ICE2 MoaE PF02391.12 EGO26539.1 - 8.2e-28 96.5 0.3 4e-13 49.2 0.0 2.0 2 0 0 2 2 2 2 MoaE protein CHAT PF12770.2 EGO26540.1 - 1.2e-31 109.8 0.0 2.4e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EGO26540.1 - 5.9e-12 45.0 9.9 0.26 10.9 0.1 9.1 4 3 5 9 9 9 4 TPR repeat TPR_12 PF13424.1 EGO26540.1 - 7.5e-10 38.6 25.2 0.0043 16.9 0.6 9.9 6 3 7 13 13 13 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO26540.1 - 0.0002 21.2 0.2 47 4.5 0.0 7.0 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26540.1 - 0.00047 19.7 3.3 0.77 9.7 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26540.1 - 0.001 18.8 4.3 4.4 7.4 0.2 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26540.1 - 0.0015 18.0 9.9 0.35 10.5 0.2 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 EGO26540.1 - 0.013 15.3 2.5 7.1 6.6 0.1 5.1 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 EGO26540.1 - 0.059 13.1 0.0 9.9 6.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO26540.1 - 2.4 8.9 20.7 0.49 11.1 0.2 7.0 5 2 4 9 9 9 0 Tetratricopeptide repeat APH PF01636.18 EGO26541.1 - 4e-11 43.0 0.0 4.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO26541.1 - 6e-06 25.9 0.0 8.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGO26541.1 - 0.059 12.4 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase BcrAD_BadFG PF01869.15 EGO26542.1 - 3.3e-14 52.8 0.0 3e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF2263 PF10021.4 EGO26543.1 - 2.5e-21 76.2 0.0 5.6e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) TraG-D_C PF12696.2 EGO26547.1 - 0.12 12.2 1.1 0.13 12.1 0.8 1.1 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG MFS_1 PF07690.11 EGO26548.1 - 2.8e-33 115.1 34.2 2.8e-33 115.1 23.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GalKase_gal_bdg PF10509.4 EGO26549.1 - 0.044 13.0 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Galactokinase galactose-binding signature ABM PF03992.11 EGO26549.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.11 EGO26550.1 - 2.9e-30 105.1 31.5 8.7e-30 103.6 21.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.7 EGO26550.1 - 0.12 12.0 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) Utp12 PF04003.7 EGO26551.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family CHAT PF12770.2 EGO26552.1 - 1.4e-31 109.7 0.0 2.2e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EGO26552.1 - 1.4e-20 72.6 11.6 0.001 18.6 0.0 8.9 2 2 7 9 9 9 8 TPR repeat TPR_12 PF13424.1 EGO26552.1 - 4.9e-16 58.4 15.6 0.74 9.7 0.1 11.1 3 2 8 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26552.1 - 1.9e-11 43.0 11.7 0.17 11.5 0.1 10.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO26552.1 - 1.4e-09 38.3 12.8 0.074 13.7 0.2 8.3 3 2 6 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26552.1 - 9.6e-07 28.2 12.6 4.7 7.3 0.1 9.8 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO26552.1 - 5.2e-05 22.7 0.4 54 3.9 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Sel1 PF08238.7 EGO26552.1 - 0.00033 21.1 0.1 46 4.8 0.0 6.5 7 0 0 7 7 6 0 Sel1 repeat Rapamycin_bind PF08771.6 EGO26552.1 - 0.0019 18.2 0.6 19 5.3 0.0 6.3 7 0 0 7 7 7 0 Rapamycin binding domain MIT PF04212.13 EGO26552.1 - 0.013 15.3 0.9 0.98 9.3 0.0 4.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Transposase_mut PF00872.13 EGO26552.1 - 0.09 11.3 0.0 2.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Transposase, Mutator family TPR_6 PF13174.1 EGO26552.1 - 0.32 11.5 5.1 92 3.8 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat ketoacyl-synt PF00109.21 EGO26553.1 - 7.7e-55 186.1 0.1 1.4e-54 185.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO26553.1 - 1.5e-49 169.0 0.7 2.5e-49 168.3 0.2 1.5 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EGO26553.1 - 1e-35 123.3 0.1 1.9e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGO26553.1 - 5.9e-28 97.1 0.0 2.8e-27 94.9 0.0 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGO26553.1 - 9.9e-28 97.0 0.1 2.5e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGO26553.1 - 5.5e-23 81.6 1.9 1.4e-22 80.3 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Thioesterase PF00975.15 EGO26553.1 - 4.1e-10 40.2 0.0 8.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_23 PF13489.1 EGO26553.1 - 0.00034 20.3 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGO26553.1 - 0.00046 19.2 0.1 0.00084 18.4 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGO26553.1 - 0.00071 19.1 0.4 0.002 17.7 0.3 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.20 EGO26553.1 - 0.00097 19.3 0.1 0.0025 18.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site OKR_DC_1 PF01276.15 EGO26553.1 - 0.18 10.3 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Methyltransf_31 PF13847.1 EGO26553.1 - 0.48 10.0 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Aminotran_5 PF00266.14 EGO26554.1 - 7.7e-17 61.0 0.0 3.4e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO26554.1 - 0.00017 20.6 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGO26554.1 - 0.031 13.3 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 EGO26555.1 - 1.2e-17 63.7 45.4 1.6e-17 63.2 31.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCHC PF00098.18 EGO26558.1 - 2.8e-07 30.1 3.7 5e-07 29.3 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26558.1 - 5.6e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO26558.1 - 0.0061 15.9 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO26558.1 - 0.046 13.4 2.0 0.1 12.3 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 EGO26559.1 - 1.2e-05 25.2 0.1 0.085 12.7 0.0 2.4 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO26559.1 - 0.00083 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO26559.1 - 0.00099 19.5 0.0 0.0028 18.1 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease XPG_I_2 PF12813.2 EGO26564.1 - 3e-09 36.7 0.0 2.8e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 EGO26564.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain RRM_1 PF00076.17 EGO26568.1 - 0.0026 17.3 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO26568.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2763 PF10961.3 EGO26568.1 - 2.9 8.3 8.9 7.4 7.0 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) API5 PF05918.6 EGO26568.1 - 9 4.6 5.9 13 4.1 4.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-CCHC_3 PF13917.1 EGO26569.1 - 6.3e-05 22.6 1.0 0.00011 21.8 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO26569.1 - 1.3 9.0 5.2 2.7 8.0 3.6 1.6 1 1 0 1 1 1 0 Zinc knuckle DUF2838 PF10998.3 EGO26572.1 - 0.03 14.2 0.9 0.7 9.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2838) Tox-HNH-HHH PF15637.1 EGO26572.1 - 1.9 8.2 4.4 5.8 6.7 0.1 3.2 3 1 0 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DNA_pol_E_B PF04042.11 EGO26573.1 - 1.6e-35 122.2 0.7 1.8e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B DUF572 PF04502.8 EGO26574.1 - 0.072 12.2 12.9 0.083 12.0 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ycf1 PF05758.7 EGO26574.1 - 4.1 4.9 9.1 3.8 5.0 6.3 1.1 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 EGO26574.1 - 7.8 5.4 14.6 11 4.9 10.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TATR PF03430.8 EGO26574.1 - 9 4.8 12.5 12 4.3 8.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator NAD_kinase PF01513.16 EGO26575.1 - 4.3e-61 206.2 0.0 5.9e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EGO26575.1 - 0.051 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CDC37_N PF03234.9 EGO26576.1 - 0.0071 16.6 1.2 0.011 16.0 0.8 1.2 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding IPPT PF01715.12 EGO26576.1 - 0.0097 14.9 1.6 0.015 14.3 1.1 1.2 1 0 0 1 1 1 1 IPP transferase DUF2497 PF10691.4 EGO26576.1 - 0.011 15.6 0.5 0.027 14.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) DUF3886 PF13025.1 EGO26576.1 - 0.52 10.3 2.4 0.53 10.2 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) Cornichon PF03311.9 EGO26577.1 - 1.6e-53 180.2 8.0 1.8e-53 180.0 5.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF4219 PF13961.1 EGO26580.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DDE_3 PF13358.1 EGO26581.1 - 1.2e-05 25.0 0.0 6.1e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DNA_RNApol_7kD PF03604.8 EGO26581.1 - 0.2 11.1 7.3 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CAS_CSE1 PF03378.10 EGO26583.1 - 2.8e-115 385.0 4.5 4e-115 384.5 3.1 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EGO26583.1 - 2e-102 342.5 0.0 3e-102 341.9 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EGO26583.1 - 3.1e-12 46.2 0.1 2.7e-11 43.2 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGO26583.1 - 0.00055 19.8 1.7 0.034 14.0 0.0 3.5 3 1 0 3 3 3 1 Exportin 1-like protein Sec10 PF07393.6 EGO26584.1 - 4.3e-132 441.7 0.0 5.3e-132 441.4 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EGO26584.1 - 0.00068 19.2 0.8 0.00068 19.2 0.5 1.9 2 0 0 2 2 2 1 F-box domain HMGL-like PF00682.14 EGO26584.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 HMGL-like Whi5 PF08528.6 EGO26585.1 - 4.8e-06 26.0 0.7 8.2e-06 25.3 0.5 1.4 1 0 0 1 1 1 1 Whi5 like CTP_transf_1 PF01148.15 EGO26586.1 - 6.2e-11 42.4 7.1 3.4e-08 33.4 2.6 2.4 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_S8 PF00410.14 EGO26587.1 - 3e-27 95.0 0.1 4.2e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 EGO26588.1 - 4.8e-57 190.9 0.2 5.7e-57 190.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Thaumatin PF00314.12 EGO26593.1 - 8.1e-62 208.4 11.4 9.4e-62 208.2 7.9 1.0 1 0 0 1 1 1 1 Thaumatin family Vps55 PF04133.9 EGO26594.1 - 0.056 13.1 0.1 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 TGS PF02824.16 EGO26596.1 - 1.5e-23 82.3 0.1 2.7e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGO26596.1 - 3.5e-18 65.6 0.2 9.5e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO26596.1 - 3.9e-09 35.9 0.5 9.8e-09 34.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGO26596.1 - 0.0039 17.0 0.5 2.8 7.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EGO26596.1 - 0.0083 14.9 0.9 0.019 13.7 0.2 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EGO26596.1 - 0.047 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EGO26596.1 - 0.097 12.1 0.1 6 6.2 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mor PF08765.6 EGO26596.1 - 0.11 12.2 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Mor transcription activator family DUF4381 PF14316.1 EGO26597.1 - 0.049 13.7 0.4 0.053 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) p450 PF00067.17 EGO26598.1 - 1.3e-57 195.3 0.0 2e-57 194.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EGO26600.1 - 1.6e-26 91.1 12.3 4e-08 32.8 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EGO26600.1 - 1.4e-05 24.8 0.1 0.0039 16.9 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EGO26600.1 - 0.17 11.5 4.3 2.6 7.7 0.1 2.9 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Adap_comp_sub PF00928.16 EGO26601.1 - 3.6e-91 304.9 0.0 5.4e-91 304.3 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO26601.1 - 1e-06 28.5 0.4 1.7e-06 27.7 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 EGO26601.1 - 0.025 13.2 0.0 0.036 12.6 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 SH3_5 PF08460.5 EGO26601.1 - 0.091 12.6 0.1 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain PQ-loop PF04193.9 EGO26602.1 - 2.3e-19 68.6 19.3 1.2e-11 43.9 1.6 3.4 3 1 0 3 3 3 2 PQ loop repeat COPI_assoc PF08507.5 EGO26602.1 - 0.71 9.5 6.1 2.3 7.9 0.0 3.2 2 1 0 2 2 2 0 COPI associated protein Retrotrans_gag PF03732.12 EGO26604.1 - 4.8e-08 32.9 0.3 4.8e-08 32.9 0.2 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO26604.1 - 2.3e-06 27.2 2.0 4.2e-06 26.4 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle BMFP PF04380.8 EGO26604.1 - 0.043 13.9 1.5 8.8 6.5 0.2 3.4 3 0 0 3 3 3 0 Membrane fusogenic activity TPR_12 PF13424.1 EGO26605.1 - 5.7e-136 442.7 65.4 3.1e-21 75.0 0.1 7.9 2 2 8 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 EGO26605.1 - 4.7e-100 325.0 12.8 8.4e-11 41.4 0.2 12.1 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26605.1 - 5.2e-42 138.3 25.0 0.002 17.7 0.1 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26605.1 - 1.3e-39 132.2 43.2 9.3e-05 21.8 0.2 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26605.1 - 1.3e-36 121.5 39.7 0.00039 20.1 0.3 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_11 PF13414.1 EGO26605.1 - 2.1e-34 117.0 29.2 6.6e-08 32.0 0.6 8.1 2 2 8 10 10 10 10 TPR repeat TPR_14 PF13428.1 EGO26605.1 - 3.8e-28 95.4 17.0 0.045 14.4 0.0 12.1 6 3 6 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGO26605.1 - 4.1e-24 84.6 30.7 7e-06 26.2 0.2 9.2 3 3 7 10 10 10 10 Tetratricopeptide repeat TPR_8 PF13181.1 EGO26605.1 - 4.6e-24 82.3 43.5 0.012 15.3 0.1 12.2 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGO26605.1 - 6e-23 80.9 18.4 0.00052 20.5 0.5 9.3 5 3 5 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 EGO26605.1 - 3.2e-22 78.4 20.6 3.4e-07 30.3 0.0 6.8 2 2 7 9 9 9 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGO26605.1 - 5.6e-15 54.2 17.6 9.5 6.7 0.0 12.4 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO26605.1 - 5.9e-14 51.4 42.3 0.099 13.1 0.2 11.6 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_4 PF07721.9 EGO26605.1 - 4e-11 42.2 0.0 21 5.9 0.0 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGO26605.1 - 1.2e-07 31.3 40.6 0.91 9.3 0.2 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat Rab5-bind PF09311.6 EGO26605.1 - 3.8e-06 26.8 13.0 1.3 8.8 0.1 6.3 3 2 2 6 6 6 2 Rabaptin-like protein PPR PF01535.15 EGO26605.1 - 4.1e-06 26.4 11.8 27 5.0 0.0 9.4 12 0 0 12 12 11 0 PPR repeat TPR_5 PF12688.2 EGO26605.1 - 8.4e-06 25.8 11.8 0.00011 22.2 0.4 5.3 4 2 0 5 5 5 1 Tetratrico peptide repeat DUF3366 PF11846.3 EGO26605.1 - 4.9e-05 23.3 2.2 0.011 15.6 0.0 4.7 2 1 1 5 5 5 1 Domain of unknown function (DUF3366) TPR_21 PF09976.4 EGO26605.1 - 0.004 17.1 19.5 0.093 12.6 0.2 6.5 2 2 1 4 4 4 2 Tetratricopeptide repeat Ribosomal_S7 PF00177.16 EGO26605.1 - 0.0084 15.6 0.3 11 5.5 0.0 4.7 4 2 1 5 5 5 0 Ribosomal protein S7p/S5e Tcf25 PF04910.9 EGO26605.1 - 0.02 13.8 12.0 1.2 7.9 0.1 5.5 4 2 4 8 8 8 0 Transcriptional repressor TCF25 Auxin_inducible PF02519.9 EGO26605.1 - 0.042 13.9 0.1 3.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Auxin responsive protein Coatomer_E PF04733.9 EGO26605.1 - 0.051 12.7 8.3 2.5 7.2 0.1 4.6 2 1 1 4 4 4 0 Coatomer epsilon subunit HpaB_N PF11794.3 EGO26605.1 - 0.12 11.7 1.5 27 4.0 0.1 3.6 1 1 2 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase N terminal SHNi-TPR PF10516.4 EGO26605.1 - 0.14 11.3 5.9 12 5.2 0.1 4.8 4 0 0 4 4 4 0 SHNi-TPR DUF2225 PF09986.4 EGO26605.1 - 0.24 10.8 16.6 0.59 9.5 3.0 4.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) NB-ARC PF00931.17 EGO26606.1 - 3.8e-13 48.9 0.0 4.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EGO26606.1 - 1.6e-06 28.1 0.1 1.1e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EGO26606.1 - 0.00044 19.9 0.0 0.0015 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO26606.1 - 0.00086 19.4 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGO26606.1 - 0.002 17.8 0.0 0.0036 16.9 0.0 1.5 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EGO26606.1 - 0.0037 16.9 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EGO26606.1 - 0.018 14.9 0.0 0.049 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO26606.1 - 0.033 13.6 0.1 0.12 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EGO26606.1 - 0.047 14.1 0.0 0.14 12.7 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 EGO26606.1 - 0.11 12.0 0.1 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Toxin_14 PF07829.6 EGO26607.1 - 2.3 8.0 6.4 6.1 6.6 4.5 1.7 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein FAD_binding_3 PF01494.14 EGO26609.1 - 7.6e-17 61.3 0.0 2.5e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO26609.1 - 0.00038 20.4 0.2 0.00092 19.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EGO26609.1 - 0.0085 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EGO26609.1 - 0.03 13.2 1.5 0.069 12.0 0.8 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO26609.1 - 0.038 13.7 0.1 0.089 12.5 0.1 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EGO26609.1 - 0.052 12.1 0.7 0.13 10.8 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 EGO26609.1 - 0.62 10.5 3.8 1.1 9.6 0.7 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.16 EGO26610.1 - 1.5e-74 251.4 0.0 2.9e-72 243.9 0.0 2.0 1 1 0 1 1 1 1 Amidase Zfx_Zfy_act PF04704.8 EGO26610.1 - 0.17 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region His_Phos_2 PF00328.17 EGO26611.1 - 1.6e-42 146.0 0.0 2.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.17 EGO26612.1 - 3.6e-73 246.6 0.0 6.3e-73 245.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3684 PF12449.3 EGO26613.1 - 0 1191.1 0.0 0 1190.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EGO26613.1 - 0.0024 17.5 0.0 0.0079 15.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGO26613.1 - 0.035 13.8 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SprT-like PF10263.4 EGO26613.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 SprT-like family Spo7 PF03907.8 EGO26615.1 - 1.1e-13 51.2 11.1 1.9e-13 50.5 2.1 2.9 2 1 0 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.4 EGO26615.1 - 0.12 12.3 0.1 0.35 10.8 0.1 1.7 1 1 0 1 1 1 0 Transmembrane protein 188 MFS_1 PF07690.11 EGO26616.1 - 2e-22 79.3 71.5 7e-19 67.7 28.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.1 EGO26616.1 - 0.063 12.4 1.4 0.17 11.1 0.9 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family PHP PF02811.14 EGO26617.1 - 2.9e-11 43.4 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 PHP domain DUF1688 PF07958.6 EGO26618.1 - 7.2e-159 528.8 0.0 8.3e-159 528.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.1 EGO26619.1 - 1.9e-13 49.5 12.2 1.9e-13 49.5 8.5 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein ETF_QO PF05187.8 EGO26620.1 - 3.7e-26 91.2 0.0 6.7e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EGO26620.1 - 2.8e-08 33.0 0.0 0.00024 20.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO26620.1 - 2.3e-06 27.4 0.0 7.9e-06 25.8 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO26620.1 - 3.8e-05 23.6 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO26620.1 - 6.7e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EGO26620.1 - 8.2e-05 21.7 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EGO26620.1 - 8.3e-05 21.5 0.0 0.00031 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGO26620.1 - 0.00033 20.4 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGO26620.1 - 0.00039 19.5 0.0 0.0007 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGO26620.1 - 0.0021 18.1 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO26620.1 - 0.0033 15.9 0.0 0.0049 15.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.1 EGO26620.1 - 0.016 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGO26620.1 - 0.022 15.1 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EGO26620.1 - 0.028 14.7 0.3 0.091 13.1 0.2 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_oxidored PF12831.2 EGO26620.1 - 0.045 12.8 0.0 0.087 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EGO26620.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.27 EGO26621.1 - 4.2e-18 64.4 5.6 1.2e-06 28.2 0.1 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 EGO26621.1 - 0.0039 16.6 0.7 3.1 7.1 0.1 3.2 3 0 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EGO26621.1 - 0.021 12.9 0.1 0.027 12.6 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Pkinase PF00069.20 EGO26622.1 - 3e-53 180.6 0.0 3.2e-51 173.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26622.1 - 4.9e-26 91.3 0.1 3.1e-25 88.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO26622.1 - 3.7e-08 32.6 0.2 3.5e-06 26.2 0.1 2.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGO26622.1 - 1.6e-05 24.7 0.2 7.9e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO26622.1 - 0.0052 15.8 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR PF01047.17 EGO26622.1 - 0.03 14.0 0.0 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 MarR family Seadorna_VP7 PF07387.6 EGO26622.1 - 0.033 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.18 EGO26624.1 - 1.3e-76 257.2 0.3 1.9e-76 256.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO26624.1 - 4.5e-17 61.6 0.0 1.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO26624.1 - 1.3e-07 30.7 3.7 7.9e-06 24.8 0.0 2.7 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EGO26624.1 - 0.0002 21.2 0.0 0.00057 19.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 EGO26624.1 - 0.59 9.5 3.0 2.3 7.6 0.0 3.0 3 1 1 4 4 4 0 DEAD_2 DUF3245 PF11595.3 EGO26624.1 - 2.3 8.4 14.6 9.8 6.4 2.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) ArfGap PF01412.13 EGO26625.1 - 3.5e-39 133.2 0.3 5.8e-39 132.4 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Toprim_Crpt PF13342.1 EGO26626.1 - 0.035 13.7 0.0 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase Hira PF07569.6 EGO26626.1 - 0.069 12.3 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split UDPG_MGDP_dh_N PF03721.9 EGO26628.1 - 5e-57 192.2 0.0 1.1e-56 191.2 0.0 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EGO26628.1 - 1.7e-36 124.5 0.1 3.8e-35 120.2 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EGO26628.1 - 9.7e-31 105.8 0.0 2.1e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EGO26628.1 - 0.0032 17.2 0.1 0.73 9.5 0.0 2.9 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EGO26628.1 - 0.026 13.5 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EGO26628.1 - 0.063 13.0 0.0 2.5 7.9 0.0 2.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain zf-CCHC PF00098.18 EGO26629.1 - 3.6e-05 23.4 3.6 3.6e-05 23.4 2.5 2.0 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26629.1 - 0.026 14.5 1.4 0.047 13.7 0.2 2.0 2 1 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO26629.1 - 0.19 11.4 3.2 0.37 10.5 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.9 EGO26630.1 - 0.091 10.7 13.5 0.12 10.3 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EGO26630.1 - 0.24 10.9 18.1 0.42 10.1 12.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 EGO26630.1 - 0.33 9.9 15.0 0.59 9.1 10.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGO26630.1 - 1.3 6.8 15.6 0.3 8.9 8.8 1.4 2 0 0 2 2 2 0 Nop14-like family zf-CCHC_4 PF14392.1 EGO26632.1 - 0.022 14.4 2.4 0.039 13.6 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle CD24 PF14984.1 EGO26632.1 - 2.6 7.9 8.6 5.4 6.8 6.0 1.5 1 0 0 1 1 1 0 CD24 protein Aminotran_1_2 PF00155.16 EGO26637.1 - 1.1e-53 182.4 0.0 5.3e-43 147.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.15 EGO26637.1 - 0.0033 16.0 0.0 0.006 15.1 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 EGO26637.1 - 0.015 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 EGO26637.1 - 0.065 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Peptidase_M20 PF01546.23 EGO26638.1 - 1.9e-30 105.7 0.0 5.1e-30 104.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO26638.1 - 2.1e-11 43.5 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain SUZ PF12752.2 EGO26639.1 - 4.4e-12 46.3 0.4 4.4e-12 46.3 0.3 2.7 3 1 0 3 3 3 1 SUZ domain FA_desaturase PF00487.19 EGO26642.1 - 3.3e-19 69.3 29.6 5.6e-19 68.5 20.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGO26642.1 - 2.2e-08 34.1 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF3458 PF11940.3 EGO26642.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Abhydrolase_3 PF07859.8 EGO26643.1 - 1.5e-45 155.3 0.0 2.1e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO26643.1 - 2.9e-07 29.9 0.3 2.1e-05 23.8 0.2 2.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EGO26643.1 - 2.4e-05 23.2 0.0 0.00022 20.0 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGO26643.1 - 0.0001 22.0 0.0 0.00013 21.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGO26643.1 - 0.00011 21.1 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EGO26643.1 - 0.002 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EGO26643.1 - 0.0024 17.7 0.3 0.0035 17.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EGO26643.1 - 0.014 14.6 0.0 0.062 12.5 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.15 EGO26643.1 - 0.17 11.2 0.2 0.9 8.9 0.1 2.3 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EGO26643.1 - 0.18 10.2 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) FA_desaturase PF00487.19 EGO26644.1 - 1.8e-25 89.8 27.5 2.8e-25 89.2 19.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGO26644.1 - 9.4e-07 28.9 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Dus PF01207.12 EGO26646.1 - 2.3e-49 167.9 0.0 8.8e-49 165.9 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EGO26646.1 - 1.7e-05 24.4 3.2 0.086 12.5 0.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Complex1_LYR PF05347.10 EGO26647.1 - 4.3e-06 26.4 1.7 0.0012 18.5 0.0 3.3 3 0 0 3 3 3 2 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO26647.1 - 0.00038 20.6 0.8 0.27 11.4 0.0 3.1 2 1 0 2 2 2 2 Complex1_LYR-like DUF2265 PF10023.4 EGO26647.1 - 0.025 13.7 0.2 0.044 12.9 0.1 1.6 1 1 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Aminotran_1_2 PF00155.16 EGO26648.1 - 1.9e-42 145.5 0.0 2.5e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 EGO26649.1 - 4.2e-27 92.9 3.7 1.3e-09 37.5 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EGO26651.1 - 6.7e-22 78.4 0.1 8.2e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO26651.1 - 0.00049 19.8 0.0 0.00096 18.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family HMGL-like PF00682.14 EGO26652.1 - 2.5e-45 155.0 0.1 1.5e-44 152.4 0.0 1.9 1 1 0 1 1 1 1 HMGL-like DUF775 PF05603.7 EGO26653.1 - 1.3e-45 155.4 0.0 1.6e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Fungal_trans PF04082.13 EGO26654.1 - 2.3e-39 134.8 0.0 6.2e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mer2 PF09074.5 EGO26655.1 - 0.0035 17.2 0.4 0.0042 17.0 0.2 1.1 1 0 0 1 1 1 1 Mer2 DUF3584 PF12128.3 EGO26655.1 - 0.038 11.3 0.2 0.043 11.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HK97-gp10_like PF04883.7 EGO26655.1 - 0.061 14.2 0.1 0.077 13.9 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Thg1C PF14413.1 EGO26655.1 - 0.11 12.1 0.3 0.12 12.0 0.2 1.0 1 0 0 1 1 1 0 Thg1 C terminal domain Dimer_Tnp_hAT PF05699.9 EGO26656.1 - 0.00035 20.1 0.3 0.00059 19.3 0.2 1.5 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region UCH PF00443.24 EGO26657.1 - 1.2e-07 31.1 0.1 2.8e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGO26657.1 - 0.00014 21.6 0.3 0.00052 19.7 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EGO26657.1 - 0.00023 20.6 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.11 EGO26657.1 - 0.0008 18.8 0.0 0.0031 16.9 0.0 2.1 2 0 0 2 2 2 1 CUE domain UIM PF02809.15 EGO26657.1 - 0.0097 15.3 0.3 0.03 13.8 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Glyco_hydro_15 PF00723.16 EGO26657.1 - 0.028 12.9 0.0 0.041 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Copper-fist PF00649.13 EGO26659.1 - 1.8e-15 55.8 9.5 2.7e-15 55.2 0.7 2.2 1 1 1 2 2 2 2 Copper fist DNA binding domain DnaJ PF00226.26 EGO26661.1 - 8.5e-19 67.0 0.4 2.8e-18 65.4 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain Pex24p PF06398.6 EGO26667.1 - 1.3e-08 34.0 2.3 2.1e-08 33.3 1.6 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Mnd1 PF03962.10 EGO26667.1 - 0.046 13.3 3.0 0.074 12.7 2.1 1.2 1 0 0 1 1 1 0 Mnd1 family Pkinase PF00069.20 EGO26668.1 - 5.4e-57 192.8 0.1 1.2e-56 191.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26668.1 - 1.7e-30 105.9 0.1 1.1e-20 73.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO26668.1 - 4.7e-05 22.4 0.0 0.027 13.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGO26668.1 - 0.004 16.9 0.1 0.04 13.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2098 PF09871.4 EGO26668.1 - 0.081 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DNA_pol_A_exo1 PF01612.15 EGO26669.1 - 2.2e-13 50.0 0.0 3.5e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease 4HBT PF03061.17 EGO26670.1 - 2.3e-07 30.8 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily FA_desaturase PF00487.19 EGO26672.1 - 9.1e-13 48.2 7.3 9.1e-13 48.2 5.0 1.7 1 1 1 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.3 EGO26672.1 - 4.1e-07 30.1 0.0 8.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Proteasome PF00227.21 EGO26673.1 - 6.4e-38 129.9 0.0 7.9e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CheX PF13690.1 EGO26673.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Mre11_DNA_bind PF04152.9 EGO26674.1 - 3.1e-50 170.4 0.4 1.3e-49 168.4 0.0 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGO26674.1 - 2.4e-26 92.3 0.7 3.5e-26 91.8 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO26674.1 - 5e-06 26.4 0.0 2.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.11 EGO26675.1 - 6.3e-11 42.1 12.7 6.3e-11 42.1 8.8 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGO26675.1 - 9.5e-05 22.4 36.6 0.00016 21.7 9.9 2.9 2 1 0 2 2 2 2 EamA-like transporter family PAPS_reduct PF01507.14 EGO26676.1 - 2.9e-27 95.5 0.0 6.7e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.16 EGO26677.1 - 5.2e-52 176.6 0.0 7.3e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO26677.1 - 3.5e-07 29.3 0.0 7.9e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO26677.1 - 1.5e-05 24.0 0.2 0.0033 16.3 0.2 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGO26677.1 - 0.0013 17.4 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO26678.1 - 5.3e-66 222.4 0.0 6.8e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO26678.1 - 1.6e-05 23.9 0.0 4.7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO26678.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO26678.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase_Csub PF13950.1 EGO26678.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Methyltransf_2 PF00891.13 EGO26680.1 - 1.1e-27 96.7 0.0 2.1e-27 95.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EGO26680.1 - 0.00017 21.3 0.6 0.00042 20.0 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain MarR PF01047.17 EGO26680.1 - 0.027 14.1 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 MarR family MTS PF05175.9 EGO26680.1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EGO26680.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Alpha_kinase PF02816.13 EGO26681.1 - 4.6e-16 59.0 0.0 8.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family Cauli_VI PF01693.11 EGO26683.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin 4HBT PF03061.17 EGO26684.1 - 2.5e-11 43.5 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EGO26684.1 - 2.2e-08 34.5 0.0 2.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EGO26684.1 - 0.0016 17.4 0.9 0.0031 16.4 0.7 1.4 1 1 1 2 2 2 1 Acyl-ACP thioesterase DUF946 PF06101.6 EGO26685.1 - 0.00011 20.3 0.0 0.00012 20.2 0.0 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF2207 PF09972.4 EGO26686.1 - 0.02 13.4 1.6 0.029 12.9 1.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.1 EGO26686.1 - 0.21 10.6 2.7 0.29 10.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) CBM_1 PF00734.13 EGO26687.1 - 1.9e-10 40.2 9.8 8.3e-10 38.1 6.8 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain p450 PF00067.17 EGO26688.1 - 8.7e-75 252.0 0.0 2.6e-73 247.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Piwi PF02171.12 EGO26689.1 - 7.5e-84 281.2 0.0 1e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EGO26689.1 - 7.5e-20 70.6 0.0 1.5e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EGO26689.1 - 8.2e-19 66.7 0.0 1.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Retrotrans_gag PF03732.12 EGO26691.1 - 7.8e-05 22.6 2.3 8.2e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EGO26692.1 - 1.8e-05 24.4 0.0 1.9e-05 24.3 0.0 1.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO26692.1 - 0.0061 17.0 0.0 0.0061 17.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO26692.1 - 0.072 13.0 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease ApbA PF02558.11 EGO26693.1 - 2.8e-18 65.7 0.0 5.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGO26693.1 - 1.7e-17 63.5 0.0 2e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 EGO26693.1 - 0.049 13.4 0.2 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family IlvN PF07991.7 EGO26693.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TPT PF03151.11 EGO26694.1 - 1.1e-23 83.5 12.7 1.6e-21 76.5 2.0 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGO26694.1 - 1.3e-09 37.4 12.3 5.6e-09 35.3 8.5 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO26694.1 - 5.4e-09 36.1 22.2 1.3e-07 31.7 3.1 3.2 3 1 1 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EGO26694.1 - 0.00015 21.9 16.1 0.001 19.2 1.0 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF2648 PF10855.3 EGO26694.1 - 0.036 13.4 0.3 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) zf-C3HC4_2 PF13923.1 EGO26695.1 - 2.1e-08 34.0 5.7 2.1e-08 34.0 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO26695.1 - 1.9e-07 30.6 4.0 1.9e-07 30.6 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO26695.1 - 2.4e-07 30.2 4.3 2.4e-07 30.2 3.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO26695.1 - 5.3e-07 29.3 6.2 5.3e-07 29.3 4.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGO26695.1 - 6.8e-06 25.8 1.7 6.8e-06 25.8 1.2 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGO26695.1 - 3.6e-05 23.3 3.8 3.6e-05 23.3 2.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO26695.1 - 7e-05 22.4 1.7 0.00014 21.5 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EGO26695.1 - 0.019 14.4 2.6 0.019 14.4 1.8 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGO26695.1 - 0.04 13.6 0.1 0.04 13.6 0.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EGO26695.1 - 1.8 8.1 13.1 3 7.4 3.0 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain AAA_11 PF13086.1 EGO26696.1 - 1.5e-59 201.4 2.1 2.1e-59 200.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGO26696.1 - 5.7e-57 192.3 0.0 1e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGO26696.1 - 2.5e-11 43.5 0.0 0.017 14.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EGO26696.1 - 1.9e-10 40.3 0.6 9.2e-10 38.1 0.2 2.4 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EGO26696.1 - 1.8e-07 30.9 0.0 2.8e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO26696.1 - 5.5e-06 26.5 0.1 0.00025 21.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGO26696.1 - 0.00059 19.7 2.4 0.0029 17.4 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 EGO26696.1 - 0.00064 19.8 0.1 0.01 15.9 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EGO26696.1 - 0.00066 19.1 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO26696.1 - 0.0013 17.7 1.5 0.3 10.0 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EGO26696.1 - 0.0031 16.8 5.5 0.012 14.8 3.8 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.24 EGO26696.1 - 0.0042 17.2 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO26696.1 - 0.0061 16.5 0.2 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.11 EGO26696.1 - 0.019 14.1 0.0 0.31 10.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein M20_dimer PF07687.9 EGO26697.1 - 7.1e-07 28.9 0.1 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EGO26697.1 - 1.9e-06 27.4 3.0 3.4e-06 26.6 2.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.23 EGO26698.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO26698.1 - 0.0054 16.4 0.1 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain UcrQ PF02939.11 EGO26700.1 - 2.2e-23 81.8 1.7 2.7e-23 81.5 1.2 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EGO26700.1 - 0.038 14.1 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Ost4 PF10215.4 EGO26701.1 - 6.6e-10 38.3 2.8 1.2e-09 37.5 1.9 1.4 1 0 0 1 1 1 1 Oligosaccaryltransferase Hydrophobin PF01185.13 EGO26704.1 - 2.2e-24 85.7 9.0 2.9e-24 85.3 6.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2771 PF10969.3 EGO26704.1 - 0.022 14.0 0.2 0.028 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) SBF PF01758.11 EGO26704.1 - 0.8 9.0 6.1 1.1 8.5 4.2 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family BMFP PF04380.8 EGO26705.1 - 0.00086 19.4 1.1 1.2 9.2 0.0 3.2 2 1 1 3 3 3 3 Membrane fusogenic activity Fer2 PF00111.22 EGO26706.1 - 1.1e-10 41.0 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FlgD_ig PF13860.1 EGO26706.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 FlgD Ig-like domain BPL_N PF09825.4 EGO26707.1 - 7.8e-18 64.3 0.0 8.6e-13 47.8 0.0 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EGO26707.1 - 2.4e-15 56.6 0.0 4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Frataxin_Cyay PF01491.11 EGO26708.1 - 2.7e-33 114.0 0.0 3.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain WD40 PF00400.27 EGO26710.1 - 4.6e-19 67.5 20.9 1.2e-08 34.4 1.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Pkinase PF00069.20 EGO26710.1 - 8.8e-19 67.6 0.0 1.6e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EGO26710.1 - 1.3e-11 43.5 12.8 0.011 15.7 0.1 6.1 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.12 EGO26710.1 - 2.3e-07 30.1 0.0 0.01 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 EGO26710.1 - 3.1e-07 30.5 1.1 0.027 14.7 0.1 3.4 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.2 EGO26710.1 - 0.033 14.0 4.0 2.3 8.0 0.3 3.0 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EGO26710.1 - 0.043 13.7 3.1 2.6 8.0 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EGO26710.1 - 3.2 8.3 8.3 3.8 8.1 0.5 4.3 4 0 0 4 4 4 0 HEAT-like repeat tRNA-synt_2b PF00587.20 EGO26711.1 - 3.2e-42 144.0 0.0 5.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO26711.1 - 2.3e-16 59.4 0.0 7.5e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 EGO26711.1 - 7.9e-14 51.2 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EGO26711.1 - 4.5e-12 45.6 0.0 9e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HSP20 PF00011.16 EGO26713.1 - 1e-12 47.8 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family COesterase PF00135.23 EGO26714.1 - 2e-95 320.5 1.5 7.7e-95 318.6 1.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO26714.1 - 3.3e-11 43.1 0.1 2.8e-10 40.1 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO26714.1 - 0.00072 18.8 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EGO26714.1 - 0.088 12.2 0.4 0.28 10.5 0.2 1.7 1 1 0 1 1 1 0 Putative esterase DUF1423 PF07227.6 EGO26715.1 - 0.21 10.2 5.5 0.25 9.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF4200 PF13863.1 EGO26715.1 - 0.38 10.6 11.1 0.53 10.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ARGLU PF15346.1 EGO26715.1 - 0.57 9.9 17.4 0.5 10.1 9.6 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 TBCC PF07986.7 EGO26719.1 - 1.1e-24 86.1 2.8 1.8e-24 85.4 1.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C zf-rbx1 PF12678.2 EGO26720.1 - 2.4e-34 117.2 13.5 3e-34 116.9 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGO26720.1 - 2.6e-16 59.2 9.5 3.4e-16 58.8 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGO26720.1 - 1.7e-06 27.7 13.1 8.6e-06 25.4 9.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO26720.1 - 0.00099 18.7 11.8 0.02 14.5 8.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO26720.1 - 0.0024 17.8 3.3 0.0024 17.8 2.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO26720.1 - 0.0042 16.7 10.1 0.43 10.3 7.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGO26720.1 - 0.17 11.8 9.3 0.79 9.7 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EGO26720.1 - 0.71 10.0 10.4 49 4.1 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EGO26720.1 - 0.86 9.3 7.1 1.2 8.9 1.6 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EGO26720.1 - 0.88 9.5 9.5 2.6 8.0 6.6 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 EGO26720.1 - 1.1 9.0 10.8 6.8 6.4 7.5 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Attractin PF08037.6 EGO26723.1 - 0.086 12.6 0.3 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 Attractin family COesterase PF00135.23 EGO26724.1 - 8.1e-48 163.4 0.3 4.3e-38 131.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO26724.1 - 0.0017 17.9 0.0 0.0058 16.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4107 PF13389.1 EGO26724.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DDE_3 PF13358.1 EGO26725.1 - 4.1e-11 42.8 0.2 4.1e-11 42.8 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease ERM PF00769.14 EGO26727.1 - 0.028 13.9 11.8 0.03 13.8 8.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Bacillus_HBL PF05791.6 EGO26727.1 - 0.078 12.3 2.1 0.088 12.1 1.5 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF1423 PF07227.6 EGO26727.1 - 0.098 11.2 6.9 0.089 11.4 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF4140 PF13600.1 EGO26727.1 - 0.13 12.7 4.1 0.15 12.5 2.8 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 EGO26727.1 - 0.25 10.2 5.9 0.25 10.2 4.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF874 PF05917.6 EGO26727.1 - 0.36 9.6 9.5 0.37 9.6 6.6 1.0 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) HAUS5 PF14817.1 EGO26727.1 - 0.4 9.1 8.5 0.38 9.2 5.9 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Seryl_tRNA_N PF02403.17 EGO26727.1 - 0.52 10.3 8.2 1.1 9.3 5.4 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 EGO26727.1 - 0.77 9.5 7.9 0.44 10.2 2.4 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper YdfA_immunity PF12127.3 EGO26727.1 - 1.6 7.5 5.2 1.7 7.4 3.6 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial Bap31 PF05529.7 EGO26727.1 - 1.7 8.0 4.9 2 7.8 3.4 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Vfa1 PF08432.5 EGO26727.1 - 1.8 8.5 7.9 2 8.4 5.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 EGO26727.1 - 1.9 7.4 7.5 1.8 7.5 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2681 PF10883.3 EGO26727.1 - 2 8.6 7.2 2.8 8.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DivIC PF04977.10 EGO26727.1 - 2.1 7.8 9.8 13 5.4 6.0 2.0 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.7 EGO26727.1 - 2.3 8.4 8.0 3 8.0 5.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) GrpE PF01025.14 EGO26727.1 - 2.8 7.4 9.6 3.2 7.2 6.7 1.1 1 0 0 1 1 1 0 GrpE DUF4407 PF14362.1 EGO26727.1 - 2.9 6.7 6.0 2.8 6.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GBP_C PF02841.9 EGO26727.1 - 5.7 6.0 13.7 6.1 5.9 9.5 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Myc-LZ PF02344.10 EGO26727.1 - 6.1 6.5 10.8 0.29 10.7 2.4 2.4 2 1 0 2 2 2 0 Myc leucine zipper domain DUF3987 PF13148.1 EGO26727.1 - 9.1 4.7 9.9 9.7 4.6 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) COesterase PF00135.23 EGO26728.1 - 2.4e-49 168.4 0.4 3.6e-38 131.5 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO26728.1 - 0.0043 16.6 0.1 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DDE_3 PF13358.1 EGO26729.1 - 4.1e-11 42.8 0.2 4.1e-11 42.8 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4470 PF14737.1 EGO26732.1 - 4e-25 87.4 0.1 8e-25 86.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) CRC_subunit PF08624.5 EGO26733.1 - 2.4e-39 134.4 0.0 3.8e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cnd2 PF05786.9 EGO26733.1 - 0.073 11.5 4.8 0.13 10.7 3.3 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 Ribosomal_L41 PF05162.8 EGO26734.1 - 2.7e-07 30.1 25.6 2.7e-07 30.1 17.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L41 Abhydrolase_2 PF02230.11 EGO26736.1 - 6.1e-11 42.1 0.0 9.8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGO26736.1 - 0.0012 18.5 0.0 0.003 17.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO26736.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO26739.1 - 1.6e-32 112.4 0.0 3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO26739.1 - 3.7e-08 33.2 0.0 8.5e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGO26739.1 - 2.3e-07 30.5 0.0 0.0095 15.3 0.1 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EGO26739.1 - 7.2e-07 29.3 0.0 2.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGO26739.1 - 4.6e-05 22.0 0.1 0.0067 14.9 0.0 2.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 EGO26739.1 - 0.0002 20.7 0.0 0.00082 18.7 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGO26739.1 - 0.0086 15.5 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EGO26739.1 - 0.014 14.9 0.0 0.044 13.3 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EGO26739.1 - 0.019 14.1 0.1 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EGO26739.1 - 0.12 11.9 0.3 0.82 9.1 0.2 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold NACHT PF05729.7 EGO26740.1 - 0.00021 21.0 0.0 0.00039 20.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain DUF1308 PF07000.6 EGO26741.1 - 8.6e-26 90.4 0.0 1.7e-25 89.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Abhydrolase_6 PF12697.2 EGO26742.1 - 4.7e-09 36.4 3.7 5e-06 26.5 0.1 2.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family RVT_2 PF07727.9 EGO26743.1 - 6.7e-08 31.7 0.1 6.9e-08 31.7 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EGO26744.1 - 9.5e-06 25.3 1.9 1.9e-05 24.3 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26744.1 - 6.6e-05 22.8 0.7 0.00034 20.6 0.5 2.3 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EGO26744.1 - 1.1 8.9 3.0 2.4 7.8 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle HTH_23 PF13384.1 EGO26748.1 - 1.5e-07 30.8 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGO26748.1 - 0.0047 16.8 0.1 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGO26748.1 - 0.021 14.1 0.1 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.2 EGO26748.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 EGO26748.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_1 PF01527.15 EGO26748.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 2 0 0 2 2 2 0 Transposase Abhydrolase_6 PF12697.2 EGO26749.1 - 3.1e-21 76.2 1.4 3.9e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO26749.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGO26749.1 - 4.6e-05 22.9 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGO26749.1 - 0.00026 20.7 0.0 0.00051 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO26749.1 - 0.011 14.9 0.0 0.027 13.7 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EGO26749.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 EGO26749.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PAF-AH_p_II PF03403.8 EGO26749.1 - 0.13 10.5 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II SET PF00856.23 EGO26753.1 - 2.4e-22 79.9 0.1 9.2e-22 78.0 0.1 1.7 1 1 0 1 1 1 1 SET domain tRNA-synt_2b PF00587.20 EGO26754.1 - 2.6e-33 115.0 0.0 4.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGO26754.1 - 1.9e-19 69.6 4.7 1.9e-19 69.6 3.2 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Hexapep PF00132.19 EGO26755.1 - 1.3e-10 40.3 18.6 4.4e-08 32.2 1.9 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO26755.1 - 1.8e-05 24.1 13.7 0.00083 18.8 2.7 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGO26755.1 - 0.13 10.7 0.1 0.22 10.0 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase UBN2 PF14223.1 EGO26756.1 - 1.2e-05 25.0 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO26756.1 - 0.0025 17.3 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_4 PF13894.1 EGO26758.1 - 0.16 12.3 5.4 0.1 12.9 1.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CCHC_4 PF14392.1 EGO26759.1 - 0.025 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO26759.1 - 0.092 12.4 0.9 0.88 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO26759.1 - 1.6 8.5 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein gag_pre-integrs PF13976.1 EGO26760.1 - 6.5e-11 41.7 0.7 1.1e-10 41.0 0.5 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain MARVEL PF01284.18 EGO26761.1 - 0.036 13.8 0.1 0.07 12.9 0.1 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF4229 PF14012.1 EGO26761.1 - 0.075 12.9 0.1 0.075 12.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) INSIG PF07281.7 EGO26761.1 - 0.076 12.3 0.7 0.15 11.3 0.5 1.5 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) TraX PF05857.6 EGO26761.1 - 0.078 12.6 5.2 0.25 10.9 3.6 1.8 1 1 0 1 1 1 0 TraX protein DUF4131 PF13567.1 EGO26761.1 - 2 7.8 4.2 3.3 7.0 1.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribonuc_2-5A PF06479.7 EGO26765.1 - 6.6e-45 152.1 0.2 1.5e-44 150.9 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EGO26765.1 - 2.7e-39 134.8 0.0 3.8e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26765.1 - 3.9e-18 65.4 0.0 1.2e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EGO26765.1 - 5e-06 26.1 0.0 8.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 EGO26765.1 - 0.0088 15.5 0.0 0.028 13.9 0.0 1.9 1 0 0 1 1 1 1 PQQ enzyme repeat Kdo PF06293.9 EGO26765.1 - 0.011 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldedh PF00171.17 EGO26766.1 - 7.9e-116 387.1 0.1 1e-115 386.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO26766.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) zf-CCCH PF00642.19 EGO26768.1 - 2.4e-07 30.2 0.9 2.4e-07 30.2 0.6 4.8 4 1 1 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO26768.1 - 1.1 9.4 30.0 0.41 10.7 2.7 4.4 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type HALZ PF02183.13 EGO26771.1 - 0.0019 17.8 1.0 0.0042 16.7 0.3 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 EGO26771.1 - 0.003 17.4 1.0 0.003 17.4 0.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor CCDC155 PF14662.1 EGO26771.1 - 0.0066 16.0 1.0 0.0097 15.5 0.7 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Shugoshin_N PF07558.6 EGO26771.1 - 0.0087 15.7 1.8 0.019 14.6 0.5 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Chibby PF14645.1 EGO26771.1 - 0.011 15.5 1.0 0.017 14.9 0.7 1.5 1 0 0 1 1 1 0 Chibby family DUF904 PF06005.7 EGO26771.1 - 0.015 15.6 2.3 0.056 13.7 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EGO26771.1 - 0.015 14.7 3.1 0.019 14.4 1.6 1.5 1 1 0 1 1 1 0 Septum formation initiator Striatin PF08232.7 EGO26771.1 - 0.016 15.5 0.5 0.024 14.9 0.4 1.3 1 0 0 1 1 1 0 Striatin family DUF972 PF06156.8 EGO26771.1 - 0.018 15.3 1.6 0.027 14.8 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) F420_ligase PF01996.11 EGO26771.1 - 0.019 14.0 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase K-box PF01486.12 EGO26771.1 - 0.047 13.4 0.9 0.084 12.6 0.6 1.5 1 0 0 1 1 1 0 K-box region TMF_TATA_bd PF12325.3 EGO26771.1 - 0.07 12.8 1.5 6.9 6.4 0.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.2 EGO26771.1 - 0.24 11.5 2.7 11 6.2 0.4 2.6 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DDE_1 PF03184.14 EGO26772.1 - 2.4e-16 59.5 0.0 3.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF316 PF03761.10 EGO26772.1 - 0.018 14.3 0.1 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Helicase_C PF00271.26 EGO26774.1 - 4.7e-17 61.6 0.0 1.5e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO26774.1 - 7.3e-13 48.3 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EGO26774.1 - 0.0047 15.5 0.0 0.0073 14.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Glucan_synthase PF02364.10 EGO26776.1 - 0 1381.3 0.0 0 1380.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGO26776.1 - 1.3e-38 131.4 0.1 4.1e-38 129.8 0.0 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NAD_binding_4 PF07993.7 EGO26777.1 - 2.1e-22 79.2 0.0 3.3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein COesterase PF00135.23 EGO26777.1 - 5.3e-13 48.5 0.1 8.9e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family AMP-binding PF00501.23 EGO26777.1 - 2.4e-11 42.7 0.0 8.4e-11 40.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EGO26777.1 - 0.00046 19.6 0.0 0.009 15.4 0.0 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGO26777.1 - 0.0068 16.6 0.1 0.14 12.4 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Peroxidase_2 PF01328.12 EGO26778.1 - 2.3e-17 62.6 0.1 3.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Yip1 PF04893.12 EGO26779.1 - 1.1e-07 31.4 21.8 1.6e-07 31.0 15.1 1.3 1 0 0 1 1 1 1 Yip1 domain AA_permease_2 PF13520.1 EGO26780.1 - 2.3e-41 141.7 42.3 3.1e-41 141.3 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO26780.1 - 9.7e-08 30.7 36.2 1.8e-07 29.9 25.1 1.4 1 1 0 1 1 1 1 Amino acid permease DUF4133 PF13571.1 EGO26780.1 - 0.031 14.4 0.5 0.55 10.4 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) ThiF PF00899.16 EGO26781.1 - 8.2e-35 119.5 0.2 1.4e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EGO26781.1 - 6.9e-05 21.9 0.4 0.00028 19.9 0.3 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 EGO26781.1 - 0.0096 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 EGO26781.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EGO26781.1 - 0.015 14.2 0.2 0.022 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EGO26781.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGO26781.1 - 0.13 12.3 0.1 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_S10 PF00450.17 EGO26782.1 - 6.4e-92 308.8 1.7 7.6e-92 308.6 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lyase_1 PF00206.15 EGO26783.1 - 1.6e-06 27.5 0.0 1.7e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Lyase Cellulase PF00150.13 EGO26784.1 - 1.4e-15 57.2 0.0 1.3e-09 37.6 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) NACHT PF05729.7 EGO26785.1 - 5.3e-08 32.6 0.0 1.9e-07 30.8 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EGO26785.1 - 0.00078 19.4 0.0 0.0034 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO26785.1 - 0.017 15.2 0.0 0.063 13.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO26785.1 - 0.054 12.8 0.1 0.35 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGO26785.1 - 0.064 13.4 0.0 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGO26785.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TauD PF02668.11 EGO26787.1 - 1e-53 182.6 1.2 1.3e-53 182.3 0.8 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EGO26787.1 - 4e-07 30.3 0.3 6e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF971) MaoC_dehydratas PF01575.14 EGO26788.1 - 3.1e-27 94.4 0.0 6.1e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGO26788.1 - 2.6e-10 40.1 0.0 4.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase APH PF01636.18 EGO26789.1 - 1.2e-12 48.0 0.0 3.1e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGO26789.1 - 0.029 13.0 0.0 0.75 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Hexokinase_2 PF03727.11 EGO26790.1 - 9.5e-80 267.3 0.0 1.3e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGO26790.1 - 6.8e-70 234.5 0.0 1e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Ribosomal_L14 PF00238.14 EGO26791.1 - 6.1e-43 145.4 2.1 6.9e-43 145.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ATP-synt PF00231.14 EGO26792.1 - 2.9e-74 250.0 7.4 3.4e-74 249.8 5.1 1.0 1 0 0 1 1 1 1 ATP synthase eIF-5_eIF-2B PF01873.12 EGO26793.1 - 7.4e-46 154.8 0.1 1.2e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EGO26793.1 - 0.0064 15.7 0.2 0.013 14.7 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.7 EGO26793.1 - 0.095 12.1 0.1 12 5.3 0.0 2.5 2 0 0 2 2 2 0 HypF finger RR_TM4-6 PF06459.7 EGO26793.1 - 1.7 8.4 9.1 2.5 7.9 6.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 EGO26794.1 - 4e-36 121.5 2.2 1.8e-07 30.7 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EGO26794.1 - 0.00014 21.6 0.0 0.07 12.8 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EGO26794.1 - 0.0047 15.7 0.0 1.2 7.8 0.0 2.7 3 0 0 3 3 3 2 Coatomer WD associated region BBS2_Mid PF14783.1 EGO26794.1 - 0.046 13.4 0.0 0.24 11.1 0.0 2.3 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF2489 PF10675.4 EGO26795.1 - 0.23 11.1 0.3 0.59 9.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Nup54 PF13874.1 EGO26796.1 - 1.8e-06 27.6 0.6 1.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Ribosomal_L27e PF01777.13 EGO26797.1 - 3.4e-36 123.2 1.0 5.3e-36 122.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGO26797.1 - 0.013 15.1 0.2 0.039 13.6 0.1 1.9 1 0 0 1 1 1 0 KOW motif PepSY_TM_1 PF13172.1 EGO26798.1 - 5.3 6.9 7.3 0.85 9.4 1.8 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO26799.1 - 4.3e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO26799.1 - 0.016 14.8 0.5 0.025 14.2 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO26799.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO26801.1 - 2e-06 27.8 2.8 2e-06 27.8 1.9 2.2 2 2 1 3 3 3 1 Retrotransposon gag protein Hydrophobin PF01185.13 EGO26802.1 - 1.9e-22 79.4 9.3 2.5e-22 79.1 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 EGO26802.1 - 9.2 6.8 10.6 12 6.5 1.2 2.6 3 0 0 3 3 3 0 Ion channel inhibitory toxin PGAP1 PF07819.8 EGO26804.1 - 6.7e-08 32.3 0.1 2.3e-07 30.6 0.1 2.0 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGO26804.1 - 3.3e-07 30.1 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO26804.1 - 5.9e-07 29.5 0.1 1e-06 28.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGO26804.1 - 0.00056 19.2 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGO26804.1 - 0.0018 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EGO26804.1 - 0.0027 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EGO26804.1 - 0.0065 16.7 0.4 0.014 15.6 0.2 1.6 1 1 0 1 1 1 1 Thioesterase domain DUF2048 PF09752.4 EGO26804.1 - 0.02 13.7 0.0 0.04 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LCAT PF02450.10 EGO26804.1 - 0.042 12.8 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.7 EGO26804.1 - 0.089 12.5 0.2 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) ETRAMP PF09716.5 EGO26804.1 - 0.11 12.4 0.6 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NARP1 PF12569.3 EGO26804.1 - 0.71 8.5 5.7 1.4 7.5 4.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TFIIS_C PF01096.13 EGO26805.1 - 1.4e-12 47.0 1.4 1.4e-12 47.0 1.0 2.7 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGO26805.1 - 8.4e-12 44.5 1.2 8.4e-12 44.5 0.8 3.4 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EGO26805.1 - 0.0013 18.9 0.3 0.0013 18.9 0.2 2.1 2 1 0 2 2 2 1 Restriction alleviation protein Lar Elf1 PF05129.8 EGO26805.1 - 0.031 13.9 6.7 0.069 12.8 0.4 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.7 EGO26805.1 - 0.044 13.8 1.4 0.044 13.8 0.9 2.8 3 1 0 3 3 2 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1 PF03811.8 EGO26805.1 - 0.063 12.7 0.4 0.063 12.7 0.3 2.6 3 0 0 3 3 3 0 InsA N-terminal domain C1_4 PF07975.7 EGO26805.1 - 0.08 12.9 10.3 0.45 10.5 0.5 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_2 PF13240.1 EGO26805.1 - 0.1 12.0 10.4 0.7 9.4 0.2 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EGO26805.1 - 0.11 12.7 4.5 3.1 8.1 0.6 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-DNA_Pol PF08996.5 EGO26805.1 - 0.12 11.6 0.2 0.12 11.6 0.1 1.9 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF2387 PF09526.5 EGO26805.1 - 0.14 12.0 0.3 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) UPF0547 PF10571.4 EGO26805.1 - 0.26 11.0 13.1 0.28 10.8 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-ISL3 PF14690.1 EGO26805.1 - 0.35 10.9 0.1 0.35 10.9 0.1 3.3 2 2 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Nudix_N_2 PF14803.1 EGO26805.1 - 0.35 10.5 9.6 7.4 6.3 0.0 3.7 3 1 0 3 3 3 0 Nudix N-terminal zf-CHY PF05495.7 EGO26805.1 - 0.36 11.0 7.0 1.8 8.7 0.2 2.4 2 0 0 2 2 2 0 CHY zinc finger GFA PF04828.9 EGO26805.1 - 0.43 10.5 5.8 3.5 7.6 0.4 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EGO26805.1 - 0.59 10.0 7.2 3.6 7.5 5.0 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 EGO26805.1 - 0.9 9.5 10.0 5.7 6.9 0.1 3.6 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EGO26805.1 - 1 9.2 11.1 3 7.7 2.3 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EGO26805.1 - 1.2 8.4 0.1 1.2 8.4 0.0 3.6 3 1 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EGO26805.1 - 1.9 8.0 6.8 26 4.4 0.4 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EGO26805.1 - 2.5 7.9 7.5 5.4 6.8 0.2 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.2 EGO26805.1 - 2.8 7.8 12.0 8.7 6.2 2.2 3.1 2 2 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.1 EGO26805.1 - 3.6 8.1 12.6 2.8 8.4 0.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger IBR PF01485.16 EGO26805.1 - 4.2 7.3 10.0 3.3e+02 1.2 6.9 2.6 1 1 0 1 1 1 0 IBR domain HypA PF01155.14 EGO26805.1 - 5.9 6.6 7.0 6.9 6.4 1.9 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 EGO26805.1 - 7.1 6.4 11.2 5.6 6.7 1.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EGO26805.1 - 8.4 6.8 10.9 8.4 6.8 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_5 PF13719.1 EGO26805.1 - 9 5.9 11.2 5.9 6.5 1.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.17 EGO26805.1 - 9 6.1 9.1 0.29 10.9 0.4 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BTB PF00651.26 EGO26807.1 - 7.4e-10 38.8 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HABP4_PAI-RBP1 PF04774.10 EGO26808.1 - 0.00014 22.3 1.3 0.00023 21.6 0.9 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Pyr_redox_3 PF13738.1 EGO26809.1 - 4.3e-24 85.7 0.0 4.1e-23 82.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO26809.1 - 9.4e-16 57.0 0.1 5.4e-15 54.5 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGO26809.1 - 1.4e-13 51.2 0.0 3.7e-11 43.3 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO26809.1 - 1.1e-09 38.5 0.1 0.0002 21.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO26809.1 - 2.3e-09 36.6 0.0 1.6e-06 27.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EGO26809.1 - 1e-06 28.0 0.1 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EGO26809.1 - 5.1e-06 26.2 0.1 0.039 13.6 0.0 2.5 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EGO26809.1 - 2.4e-05 23.5 0.1 0.018 14.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EGO26809.1 - 0.00032 19.6 0.2 0.0029 16.5 0.0 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGO26809.1 - 0.0007 19.5 0.0 0.0073 16.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.10 EGO26809.1 - 0.0077 16.0 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGO26809.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EGO26809.1 - 0.009 14.5 0.2 0.3 9.4 0.0 3.1 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.19 EGO26809.1 - 0.01 14.7 0.6 0.16 10.8 0.1 2.6 3 1 0 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EGO26809.1 - 0.016 15.2 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 EGO26809.1 - 0.016 15.2 0.0 7 6.7 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGO26809.1 - 0.04 13.3 0.0 0.16 11.3 0.0 2.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGO26809.1 - 0.041 13.7 0.2 0.28 10.9 0.1 2.3 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 EGO26809.1 - 0.069 12.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EGO26809.1 - 0.07 11.9 0.1 0.15 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EGO26809.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.1 EGO26809.1 - 0.16 12.2 0.1 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain Thaumatin PF00314.12 EGO26810.1 - 5.4e-63 212.2 17.0 6.1e-63 212.1 11.8 1.0 1 0 0 1 1 1 1 Thaumatin family Amidase PF01425.16 EGO26812.1 - 5.4e-73 246.3 0.0 8.7e-72 242.3 0.0 2.0 1 1 0 1 1 1 1 Amidase zf-C3HC4_2 PF13923.1 EGO26813.1 - 6.6e-08 32.4 21.5 4.3e-05 23.4 1.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO26813.1 - 2.1e-06 27.2 22.0 0.005 16.4 8.1 2.8 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EGO26813.1 - 8.5e-06 25.1 12.8 0.0007 18.8 0.8 2.6 2 1 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4 PF00097.20 EGO26813.1 - 6.7e-05 22.4 21.6 0.025 14.2 2.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO26813.1 - 7e-05 22.4 22.2 0.00019 21.1 6.6 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 EGO26813.1 - 0.00015 21.5 20.9 0.0094 15.7 1.5 2.8 2 1 1 3 3 3 2 Ring finger domain Atg14 PF10186.4 EGO26813.1 - 0.047 12.6 4.7 0.098 11.5 3.3 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3039 PF11238.3 EGO26813.1 - 0.15 11.5 0.3 0.15 11.5 0.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3039) zf-RING_UBOX PF13445.1 EGO26813.1 - 0.99 9.1 14.1 7.1 6.4 4.5 3.3 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGO26813.1 - 1.5 8.7 19.5 0.12 12.2 1.2 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGO26813.1 - 2.2 8.1 9.3 1.4 8.7 0.3 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Glyco_hydro_31 PF01055.21 EGO26814.1 - 2.5e-91 306.7 5.4 3.5e-91 306.2 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO26814.1 - 6.3e-07 29.1 0.0 1.6e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like EIF_2_alpha PF07541.7 EGO26816.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Cellulase PF00150.13 EGO26817.1 - 7.2e-09 35.2 0.8 3.7e-08 32.9 0.5 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF543 PF04418.7 EGO26819.1 - 4.6e-28 96.9 0.1 5.3e-28 96.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) F-box-like PF12937.2 EGO26820.1 - 4.4e-08 32.7 0.4 7.9e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like COesterase PF00135.23 EGO26821.1 - 1.2e-92 311.4 0.0 2e-92 310.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO26821.1 - 0.00058 19.4 0.0 0.0021 17.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Rab3-GTPase_cat PF13890.1 EGO26821.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Abhydrolase_6 PF12697.2 EGO26821.1 - 0.039 13.8 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO26821.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Myb_Cef PF11831.3 EGO26822.1 - 1.7e-59 200.8 1.4 1.7e-59 200.8 1.0 3.6 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EGO26822.1 - 8.9e-20 70.4 6.9 8.2e-11 41.7 0.4 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO26822.1 - 6.9e-17 61.3 3.7 3e-12 46.4 2.2 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Velvet PF11754.3 EGO26823.1 - 6e-27 94.5 0.0 1.3e-26 93.4 0.0 1.5 1 1 0 1 1 1 1 Velvet factor BAH PF01426.13 EGO26824.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 BAH domain PHD PF00628.24 EGO26824.1 - 0.21 11.3 2.2 2.7 7.7 1.0 2.4 2 0 0 2 2 2 0 PHD-finger TB2_DP1_HVA22 PF03134.14 EGO26825.1 - 2.2e-09 36.9 0.9 3.9e-09 36.1 0.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Fungal_trans PF04082.13 EGO26826.1 - 7.6e-16 57.7 0.1 1.9e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO26826.1 - 0.00022 21.0 14.9 0.00044 20.1 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 EGO26827.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain NAD_binding_6 PF08030.7 EGO26828.1 - 2.9e-37 127.9 0.0 5.3e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO26828.1 - 6.4e-23 80.6 0.0 1.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGO26828.1 - 7.5e-16 58.3 11.8 7.5e-16 58.3 8.2 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGO26828.1 - 1.1e-05 25.4 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO26828.1 - 0.093 13.3 0.1 1.7 9.2 0.1 2.5 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain Glyco_hydro_28 PF00295.12 EGO26829.1 - 8.7e-38 130.0 0.0 2.2e-37 128.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 BEX PF04538.7 EGO26829.1 - 0.12 12.5 0.4 0.23 11.6 0.3 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family His_Phos_2 PF00328.17 EGO26830.1 - 1.5e-07 31.1 0.0 3.8e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 EGO26831.1 - 4.8e-07 29.4 0.1 5.3e-05 22.7 0.1 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VIT1 PF01988.14 EGO26832.1 - 9.4e-68 227.8 6.6 1.1e-67 227.6 4.6 1.0 1 0 0 1 1 1 1 VIT family DUF2013 PF09431.5 EGO26833.1 - 2.3e-47 160.2 0.3 5.1e-47 159.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) CLN3 PF02487.12 EGO26834.1 - 1.2e-63 215.2 5.4 1.3e-61 208.5 3.7 2.1 1 1 0 1 1 1 1 CLN3 protein Vps26 PF03643.10 EGO26835.1 - 1.8e-129 430.3 3.1 2.1e-129 430.1 2.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGO26835.1 - 0.0088 15.8 0.6 2 8.2 0.2 3.4 1 1 2 3 3 3 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.27 EGO26838.1 - 1.6e-30 103.8 12.5 3.9e-10 39.2 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EGO26838.1 - 2.2e-27 94.9 5.3 4.4e-27 93.9 3.6 1.5 1 0 0 1 1 1 1 Sof1-like domain Coatomer_WDAD PF04053.9 EGO26838.1 - 0.012 14.4 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region DUF2259 PF10016.4 EGO26838.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Plus-3 PF03126.13 EGO26839.1 - 1.5e-21 76.4 0.1 4.5e-19 68.4 0.0 2.9 1 1 0 1 1 1 1 Plus-3 domain F-box-like PF12937.2 EGO26840.1 - 4.6e-05 23.0 0.5 0.00031 20.4 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EGO26840.1 - 0.00033 20.2 0.7 0.0015 18.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain Methyltransf_3 PF01596.12 EGO26844.1 - 1.9e-43 147.9 0.1 2.4e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGO26844.1 - 1.8e-17 64.1 0.0 3.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO26844.1 - 2.7e-12 46.5 0.0 6.1e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO26844.1 - 1.9e-11 44.4 0.0 3.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO26844.1 - 2.2e-07 30.9 0.0 5.3e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO26844.1 - 7.9e-06 25.5 0.0 9.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGO26844.1 - 0.00013 21.1 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGO26844.1 - 0.00013 21.1 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EGO26844.1 - 0.00015 22.2 0.0 0.00041 20.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EGO26844.1 - 0.0021 17.3 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Cons_hypoth95 PF03602.10 EGO26844.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Peptidase_S10 PF00450.17 EGO26845.1 - 5.9e-93 312.2 2.9 7e-93 312.0 2.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3079 PF11278.3 EGO26845.1 - 0.097 12.2 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) AA_permease_2 PF13520.1 EGO26847.1 - 9.2e-52 176.0 55.5 1.1e-51 175.7 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO26847.1 - 1.9e-25 89.1 49.4 2.5e-25 88.7 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease COX2-transmemb PF09125.5 EGO26847.1 - 4.1 7.0 6.6 43 3.7 0.0 3.6 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane 2OG-FeII_Oxy PF03171.15 EGO26848.1 - 8.8e-15 54.8 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO26848.1 - 2.7e-13 50.4 0.0 8.3e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal GHL15 PF14885.1 EGO26848.1 - 0.075 13.2 0.1 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Retrotrans_gag PF03732.12 EGO26849.1 - 6e-07 29.4 0.2 6e-07 29.4 0.1 2.9 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO26849.1 - 5.5e-06 26.0 0.5 1.1e-05 25.0 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle MutS_V PF00488.16 EGO26851.1 - 4.3e-24 85.2 0.2 6.6e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_II PF05188.12 EGO26852.1 - 3.3e-17 62.8 0.1 1.2e-16 61.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain II MutS_III PF05192.13 EGO26852.1 - 1.7e-12 47.6 0.1 6.1e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 MutS domain III BAH PF01426.13 EGO26853.1 - 0.018 14.7 0.0 0.054 13.2 0.0 1.9 1 1 0 1 1 1 0 BAH domain DIOX_N PF14226.1 EGO26855.1 - 7.9e-17 61.8 0.0 1.8e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO26855.1 - 1.7e-11 44.2 0.0 4.4e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3712 PF12505.3 EGO26856.1 - 0.011 15.7 0.0 0.85 9.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3712) GWT1 PF06423.7 EGO26857.1 - 4.7e-39 133.5 0.0 1.5e-38 131.9 0.0 1.9 1 0 0 1 1 1 1 GWT1 Ribosomal_L28 PF00830.14 EGO26858.1 - 4.5e-22 77.6 0.8 7e-22 77.0 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Selenoprotein_S PF06936.6 EGO26858.1 - 0.28 10.7 5.5 0.38 10.2 3.8 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1764 PF08576.5 EGO26858.1 - 2.6 8.8 6.6 5.7 7.7 4.6 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CAF-1_p150 PF11600.3 EGO26858.1 - 4.1 6.7 23.0 6.4 6.0 15.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NT-C2 PF10358.4 EGO26859.1 - 8.2e-20 70.7 0.0 7.4e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins SET PF00856.23 EGO26865.1 - 1e-08 35.6 0.0 1.4e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 SET domain DUF4267 PF14087.1 EGO26867.1 - 0.079 12.5 0.3 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) PepSY_TM_1 PF13172.1 EGO26867.1 - 2.2 8.1 0.1 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 PepSY-associated TM helix zf-FCS PF06467.9 EGO26868.1 - 0.016 14.8 0.4 0.016 14.8 0.2 1.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif F-box PF00646.28 EGO26869.1 - 6.1e-05 22.5 0.3 0.00013 21.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO26869.1 - 0.1 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like zf-ribbon_3 PF13248.1 EGO26869.1 - 0.61 9.3 5.0 2.6 7.3 3.5 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DDHD PF02862.12 EGO26872.1 - 0.079 12.7 0.3 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 DDHD domain VHS PF00790.14 EGO26873.1 - 3.6e-25 88.2 0.0 7.9e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EGO26873.1 - 1.8e-08 34.2 1.6 7.3e-07 29.1 0.3 2.6 2 0 0 2 2 2 1 GAT domain HEAT_2 PF13646.1 EGO26873.1 - 0.029 14.6 0.3 0.66 10.3 0.0 2.7 2 1 1 3 3 3 0 HEAT repeats EF1_GNE PF00736.14 EGO26873.1 - 0.048 13.3 0.4 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain Ycf1 PF05758.7 EGO26873.1 - 0.19 9.4 7.3 0.25 9.0 5.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF445 PF04286.7 EGO26873.1 - 0.95 8.9 9.9 1.5 8.2 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CN_hydrolase PF00795.17 EGO26874.1 - 7.8e-30 103.6 0.0 1e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF35 PF01796.12 EGO26874.1 - 0.029 14.5 0.1 13 6.0 0.0 2.8 3 0 0 3 3 3 0 DUF35 OB-fold domain Proteasome_A_N PF10584.4 EGO26874.1 - 0.098 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EGO26875.1 - 2.4e-41 138.1 12.4 2.1e-09 36.9 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGO26875.1 - 0.023 12.8 0.1 4.4 5.3 0.0 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO26875.1 - 0.18 10.5 0.0 4.1 6.0 0.0 2.9 2 2 0 3 3 3 0 Nup133 N terminal like WD40 PF00400.27 EGO26876.1 - 7.6e-48 158.7 12.8 2.6e-13 49.2 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 EGO26876.1 - 0.0001 20.6 1.2 0.22 9.5 0.1 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Robl_LC7 PF03259.12 EGO26876.1 - 0.014 14.8 0.1 2.9 7.5 0.1 2.9 2 1 1 3 3 3 0 Roadblock/LC7 domain Fibrinogen_aC PF12160.3 EGO26876.1 - 0.036 13.5 0.3 12 5.4 0.0 3.3 1 1 2 3 3 3 0 Fibrinogen alpha C domain PD40 PF07676.7 EGO26876.1 - 0.12 12.0 4.2 3.8 7.2 0.1 3.8 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 EGO26878.1 - 6e-18 64.6 18.6 6e-18 64.6 12.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO26878.1 - 4e-06 25.6 12.8 6.9e-06 24.9 8.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter PDR_assoc PF08370.6 EGO26878.1 - 0.044 13.2 1.6 6.8 6.2 0.1 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Iso_dh PF00180.15 EGO26879.1 - 2.3e-71 240.5 0.0 2.8e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHFR_2 PF06442.6 EGO26879.1 - 0.081 12.5 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase PNP_UDP_1 PF01048.15 EGO26880.1 - 2.1e-40 138.1 0.1 2.7e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ADH_zinc_N PF00107.21 EGO26883.1 - 8.1e-22 77.1 0.2 1.5e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO26883.1 - 1.2e-06 29.4 0.2 3.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EGO26885.1 - 4.4e-71 239.0 0.0 6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26885.1 - 1.3e-32 112.9 0.0 1.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO26885.1 - 2.8e-05 23.2 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGO26885.1 - 0.016 14.5 0.3 0.05 12.9 0.0 1.9 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGO26885.1 - 0.019 14.0 0.7 0.029 13.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO26885.1 - 0.049 13.3 0.0 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RTA1 PF04479.8 EGO26888.1 - 3.4e-38 131.3 0.5 3.4e-38 131.3 0.3 1.4 2 0 0 2 2 2 1 RTA1 like protein DAO PF01266.19 EGO26889.1 - 5.9e-52 176.7 0.3 2.8e-51 174.5 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 EGO26889.1 - 6.2e-05 22.2 0.0 0.035 13.2 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.9 EGO26889.1 - 0.0001 22.2 0.1 0.87 9.4 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO26889.1 - 0.00015 21.6 0.0 0.0004 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGO26889.1 - 0.00041 19.1 0.2 0.0044 15.6 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EGO26889.1 - 0.00069 19.9 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO26889.1 - 0.0049 16.6 0.1 0.062 13.0 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EGO26889.1 - 0.0094 14.8 0.1 0.25 10.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Saccharop_dh PF03435.13 EGO26889.1 - 0.1 11.5 0.1 0.69 8.8 0.1 2.2 2 1 1 3 3 3 0 Saccharopine dehydrogenase Thi4 PF01946.12 EGO26889.1 - 0.16 11.0 0.1 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family WH1 PF00568.18 EGO26891.1 - 1.5e-12 47.2 1.5 4e-10 39.3 0.5 2.1 2 0 0 2 2 2 2 WH1 domain PBD PF00786.23 EGO26891.1 - 0.0034 17.7 0.2 0.01 16.2 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pyr_redox_2 PF07992.9 EGO26892.1 - 6.9e-25 88.1 0.0 8.9e-18 64.8 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO26892.1 - 1.5e-11 44.5 0.0 5e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO26892.1 - 0.0022 18.0 0.0 0.02 14.9 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO26892.1 - 0.13 11.1 0.0 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.20 EGO26893.1 - 3.4e-32 111.6 0.0 1.9e-31 109.1 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26893.1 - 1.3e-18 66.9 0.0 5.9e-17 61.5 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO26893.1 - 2.5e-06 26.6 0.0 1.6e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGO26893.1 - 0.031 14.0 2.2 0.048 13.3 0.1 2.4 3 1 1 4 4 4 0 Phosphotransferase enzyme family Cupin_2 PF07883.6 EGO26894.1 - 4.7e-07 29.2 0.1 7.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGO26894.1 - 9.5e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EGO26894.1 - 0.00091 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGO26894.1 - 0.012 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.9 EGO26894.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Pox_F11 PF04943.7 EGO26894.1 - 0.039 12.8 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Cupin_3 PF05899.7 EGO26894.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SYF2 PF08231.7 EGO26895.1 - 2.3e-49 167.4 6.8 2.3e-49 167.4 4.7 2.2 2 1 0 2 2 2 1 SYF2 splicing factor Hemagglutinin PF00509.13 EGO26895.1 - 0.066 11.3 0.2 0.11 10.5 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin Smg4_UPF3 PF03467.10 EGO26896.1 - 2.2e-31 109.1 0.0 3.9e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF2413 PF10310.4 EGO26896.1 - 0.38 9.5 13.6 0.8 8.4 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MFS_1 PF07690.11 EGO26897.1 - 1.2e-23 83.4 28.6 4.7e-17 61.7 15.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 EGO26899.1 - 1.4e-05 25.0 0.1 3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TIMELESS PF04821.9 EGO26900.1 - 1.5e-45 155.5 0.0 6.2e-45 153.5 0.0 2.2 2 0 0 2 2 2 1 Timeless protein Polysacc_synt_4 PF04669.8 EGO26900.1 - 2.4e-20 72.7 0.2 1.3e-19 70.3 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis TIMELESS_C PF05029.8 EGO26900.1 - 7.1e-17 61.5 0.1 7.1e-17 61.5 0.1 3.2 2 1 0 3 3 3 1 Timeless protein C terminal region bZIP_1 PF00170.16 EGO26902.1 - 3.8e-05 23.5 8.8 0.0022 17.8 2.2 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EGO26902.1 - 0.00054 19.7 12.9 0.0018 18.0 0.6 2.5 3 0 0 3 3 3 2 Basic region leucine zipper NYD-SP28_assoc PF14775.1 EGO26902.1 - 0.0039 16.8 1.5 0.0039 16.8 1.0 2.1 2 0 0 2 2 2 1 Sperm tail C-terminal domain DUF972 PF06156.8 EGO26902.1 - 0.0044 17.3 0.1 0.01 16.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF2216 PF10226.4 EGO26902.1 - 0.017 14.6 1.3 0.059 12.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) HALZ PF02183.13 EGO26902.1 - 0.048 13.3 1.1 0.12 12.0 0.7 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.13 EGO26902.1 - 0.11 12.4 2.3 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.1 EGO26902.1 - 0.18 11.8 4.2 0.073 13.0 0.6 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 EGO26902.1 - 1.4 8.4 7.7 1.5 8.3 0.9 2.3 1 1 0 2 2 2 0 Septum formation initiator Shugoshin_N PF07558.6 EGO26902.1 - 1.6 8.4 7.0 2.1 8.1 2.4 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Transaldolase PF00923.14 EGO26903.1 - 4.8e-17 62.0 0.0 3e-13 49.5 0.0 2.3 1 1 1 2 2 2 2 Transaldolase AA_permease PF00324.16 EGO26904.1 - 5e-119 397.7 46.8 6.2e-119 397.4 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO26904.1 - 1.3e-30 106.3 51.4 2.3e-30 105.4 35.6 1.4 1 1 0 1 1 1 1 Amino acid permease IncA PF04156.9 EGO26904.1 - 0.28 10.7 0.0 0.28 10.7 0.0 3.1 3 0 0 3 3 3 0 IncA protein PrgI PF12666.2 EGO26904.1 - 0.84 9.8 0.0 0.84 9.8 0.0 4.3 5 0 0 5 5 5 0 PrgI family protein Hydrolase_6 PF13344.1 EGO26905.1 - 6.4e-29 99.8 0.0 1.6e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO26905.1 - 1.1e-16 60.2 0.0 2.7e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO26905.1 - 9.5e-10 39.2 0.0 1.3e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO26905.1 - 0.00072 19.8 0.1 0.26 11.4 0.1 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EGO26905.1 - 0.022 14.1 0.0 0.073 12.4 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ribosomal_L34e PF01199.13 EGO26907.1 - 3e-38 129.9 4.2 4.2e-38 129.4 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 EGO26907.1 - 2.5 7.8 6.3 7.2 6.3 0.2 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Tetraspannin PF00335.15 EGO26908.1 - 0.005 16.1 9.8 0.005 16.1 6.8 2.0 2 1 0 2 2 2 1 Tetraspanin family UPF0233 PF06781.7 EGO26908.1 - 0.019 14.5 0.2 0.06 12.9 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Ribosomal_L31e PF01198.14 EGO26909.1 - 5.4e-29 99.6 0.2 5.4e-29 99.6 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L31e CAP59_mtransfer PF11735.3 EGO26910.1 - 4.3e-71 238.9 0.1 5.8e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 EGO26910.1 - 0.06 12.5 0.1 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Ion transport protein WW PF00397.21 EGO26912.1 - 2.3e-07 30.5 4.5 2.3e-07 30.5 3.1 2.0 2 0 0 2 2 2 1 WW domain Usp PF00582.21 EGO26913.1 - 1.1e-13 51.6 0.2 1.5e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family MobC PF05713.6 EGO26914.1 - 0.3 11.0 2.6 1.4 8.9 0.4 2.5 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) RNase_PH PF01138.16 EGO26916.1 - 7.3e-28 97.5 0.1 1.5e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 ABC_tran PF00005.22 EGO26917.1 - 3.7e-34 117.9 0.0 5.8e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGO26917.1 - 7.6e-08 31.8 0.3 7.7e-06 25.2 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGO26917.1 - 7e-07 28.1 0.0 1.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 EGO26917.1 - 4.5e-06 26.7 0.1 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EGO26917.1 - 1.5e-05 25.1 0.0 0.024 14.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO26917.1 - 3.1e-05 24.1 0.1 0.00053 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGO26917.1 - 6.5e-05 22.4 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EGO26917.1 - 0.00012 22.8 0.0 0.00022 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO26917.1 - 0.00072 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGO26917.1 - 0.0011 19.0 0.4 0.18 11.7 0.3 2.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO26917.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_membrane PF00664.18 EGO26917.1 - 0.0022 17.4 0.8 0.0032 16.9 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.1 EGO26917.1 - 0.0029 17.0 0.0 0.0075 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EGO26917.1 - 0.0076 15.9 0.0 0.088 12.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EGO26917.1 - 0.0088 15.6 0.1 0.027 14.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGO26917.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EGO26917.1 - 0.016 15.3 0.0 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGO26917.1 - 0.022 14.1 0.0 4.1 6.7 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain AAA_19 PF13245.1 EGO26917.1 - 0.025 14.3 0.3 0.16 11.7 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain PRK PF00485.13 EGO26917.1 - 0.035 13.6 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 EGO26917.1 - 0.037 12.6 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.1 EGO26917.1 - 0.041 13.7 0.1 0.08 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO26917.1 - 0.059 12.7 0.1 0.28 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EGO26917.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 EGO26917.1 - 0.062 12.2 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EGO26917.1 - 0.062 13.1 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EGO26917.1 - 0.073 13.3 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGO26917.1 - 0.088 12.7 0.3 1.4 8.8 0.0 2.5 3 1 0 3 3 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EGO26917.1 - 0.093 12.3 0.0 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO26917.1 - 0.15 12.0 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Con-6 PF10346.4 EGO26918.1 - 3.7e-36 122.2 5.4 2.4e-18 65.2 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 S6PP PF05116.8 EGO26919.1 - 0.14 11.3 0.1 0.15 11.3 0.1 1.0 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Chitin_synth_2 PF03142.10 EGO26922.1 - 1.7e-238 792.3 0.2 2.5e-238 791.8 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGO26922.1 - 6e-158 526.9 0.0 8.1e-158 526.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EGO26922.1 - 1.7e-16 59.6 0.8 8e-16 57.5 0.3 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EGO26922.1 - 2.9e-13 49.4 0.1 8.8e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EGO26922.1 - 2.5e-12 47.0 0.0 6e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGO26922.1 - 7.8e-11 42.0 2.8 7.8e-11 42.0 2.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGO26922.1 - 0.00051 19.7 0.0 0.1 12.3 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_29 PF13555.1 EGO26922.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGO26922.1 - 0.14 11.2 0.0 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin YwiC PF14256.1 EGO26922.1 - 6.9 6.7 11.5 0.14 12.1 0.7 2.8 2 1 0 2 2 2 0 YwiC-like protein DUF3543 PF12063.3 EGO26923.1 - 2e-16 59.9 0.0 2.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) HTH_29 PF13551.1 EGO26923.1 - 0.13 12.4 1.8 0.52 10.4 0.0 2.5 2 1 1 3 3 3 0 Winged helix-turn helix Pkinase PF00069.20 EGO26925.1 - 3.1e-20 72.4 0.0 3.2e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26925.1 - 4.2e-14 52.2 0.0 4.5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_Me_trans PF04252.8 EGO26926.1 - 1.9e-37 128.5 0.0 7.2e-37 126.7 0.0 1.8 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Aminotran_1_2 PF00155.16 EGO26927.1 - 2.6e-39 135.2 0.0 3.1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGO26927.1 - 0.025 12.8 0.0 0.043 12.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGO26927.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Thr_synth_N PF14821.1 EGO26929.1 - 7.7e-29 99.5 0.0 2.6e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EGO26929.1 - 1.5e-18 67.1 0.1 2.5e-17 63.0 0.1 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ROS_MUCR PF05443.6 EGO26929.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein FAD_binding_3 PF01494.14 EGO26930.1 - 2.4e-21 76.2 0.0 5.5e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO26930.1 - 3.3e-05 23.8 0.7 0.00012 22.0 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGO26930.1 - 0.00013 20.7 0.9 0.011 14.3 0.1 2.8 2 1 1 3 3 3 1 Tryptophan halogenase DAO PF01266.19 EGO26930.1 - 0.0002 20.3 0.9 0.00084 18.3 0.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO26930.1 - 0.025 14.6 0.2 0.057 13.4 0.1 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO26930.1 - 0.053 12.3 2.4 0.088 11.6 1.6 1.3 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 EGO26930.1 - 0.057 12.2 0.0 0.13 11.0 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EGO26930.1 - 0.061 12.4 0.2 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EGO26930.1 - 0.084 12.7 1.2 0.16 11.8 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO26930.1 - 0.14 12.5 0.6 0.31 11.4 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO26930.1 - 0.19 11.4 0.8 0.61 9.8 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding STAG PF08514.6 EGO26931.1 - 6.5e-28 96.8 0.2 4.2e-27 94.1 0.1 2.5 1 1 1 2 2 2 1 STAG domain HEAT_2 PF13646.1 EGO26931.1 - 2.8e-08 33.9 0.0 8.6e-05 22.7 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats eIF3_subunit PF08597.5 EGO26931.1 - 0.0011 18.5 7.2 0.0011 18.5 5.0 3.8 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit HEAT PF02985.17 EGO26931.1 - 0.005 16.8 2.2 8.7 6.7 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat DUF1319 PF07028.6 EGO26934.1 - 0.069 13.3 1.9 0.15 12.2 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Fib_alpha PF08702.5 EGO26934.1 - 0.34 11.0 4.3 0.13 12.3 0.9 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3837 PF12939.2 EGO26934.1 - 0.94 9.5 3.8 1.1 9.2 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Pkinase PF00069.20 EGO26935.1 - 1.2e-34 119.6 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26935.1 - 1.5e-13 50.4 0.1 2.2e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO26935.1 - 2.4e-06 26.7 0.0 3.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO26935.1 - 0.0083 15.2 0.2 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO26935.1 - 0.028 14.1 0.1 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBM_19 PF03427.8 EGO26937.1 - 0.095 12.4 0.8 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DHHA2 PF02833.9 EGO26938.1 - 8.5e-12 45.3 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EGO26938.1 - 2.2e-11 43.5 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 DHH family Complex1_LYR_1 PF13232.1 EGO26939.1 - 1.1e-15 57.5 0.9 1.4e-15 57.1 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGO26939.1 - 1.1e-11 44.3 0.2 1.5e-11 43.9 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2524 PF10732.4 EGO26939.1 - 0.085 12.9 0.1 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Urm1 PF09138.6 EGO26940.1 - 1e-33 115.2 0.0 3e-28 97.7 0.0 2.0 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGO26940.1 - 8.1e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 ThiS family FMN_dh PF01070.13 EGO26941.1 - 8.3e-104 347.2 0.0 1.1e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EGO26941.1 - 7e-06 25.4 0.5 1e-05 24.8 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EGO26941.1 - 3.6e-05 22.8 0.1 5.2e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EGO26941.1 - 0.00021 20.3 0.2 0.00055 18.9 0.1 1.7 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 EGO26941.1 - 0.00022 20.2 0.5 0.00044 19.2 0.3 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EGO26941.1 - 0.022 13.8 0.8 0.24 10.4 0.1 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGO26941.1 - 0.052 12.8 0.6 0.46 9.7 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein Ribosomal_S30 PF04758.9 EGO26942.1 - 9.2e-31 105.3 6.7 1e-30 105.2 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pterin_bind PF00809.17 EGO26943.1 - 1e-49 168.7 0.0 1.7e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EGO26943.1 - 2.1e-33 114.7 0.0 1.3e-32 112.1 0.0 2.1 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EGO26943.1 - 4.1e-30 104.2 0.0 6.4e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase TPR_16 PF13432.1 EGO26944.1 - 6.1e-10 39.5 0.7 7.5e-07 29.6 0.1 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO26944.1 - 1.4e-07 31.5 5.1 0.00036 20.9 0.2 5.1 5 2 1 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO26944.1 - 1.3e-06 27.9 0.0 0.00014 21.4 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 EGO26944.1 - 1.7e-06 28.2 1.9 0.00031 21.0 1.0 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO26944.1 - 2.2e-06 27.1 0.0 0.0011 18.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO26944.1 - 5e-06 25.8 0.5 0.00061 19.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO26944.1 - 1.7e-05 24.2 0.1 0.0035 17.0 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO26944.1 - 0.00028 21.1 3.1 4.4 7.9 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO26944.1 - 0.0057 16.3 0.7 0.14 11.9 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO26944.1 - 0.0084 16.0 1.0 0.12 12.3 0.2 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO26944.1 - 0.0089 16.1 0.2 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO26944.1 - 0.012 15.4 0.2 1.6 8.6 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO26944.1 - 0.021 14.9 0.6 0.16 12.1 0.3 2.4 2 1 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EGO26944.1 - 0.054 13.6 0.1 2.3 8.3 0.2 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGO26944.1 - 0.054 13.4 0.2 3.7 7.4 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EGO26944.1 - 0.065 12.2 1.8 2.1 7.3 0.8 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3151 PF11349.3 EGO26944.1 - 0.095 12.7 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) Peptidase_S24 PF00717.18 EGO26945.1 - 8.2e-10 38.1 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Fungal_trans PF04082.13 EGO26947.1 - 3.2e-12 45.8 0.1 4.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 EGO26948.1 - 4.3e-29 101.3 28.2 7.2e-29 100.6 19.6 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GTP1_OBG PF01018.17 EGO26949.1 - 5.7e-39 133.2 1.7 2.8e-27 95.3 0.1 3.0 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 EGO26949.1 - 1.5e-17 63.5 0.0 3.3e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO26949.1 - 0.00017 21.1 0.0 0.069 12.5 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO26949.1 - 0.0003 20.6 0.0 0.001 18.8 0.0 2.0 1 1 0 1 1 1 1 Dynamin family cobW PF02492.14 EGO26949.1 - 0.00036 20.0 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EGO26949.1 - 0.00037 19.8 0.0 0.00073 18.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGO26949.1 - 0.0013 19.2 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EGO26949.1 - 0.0024 17.1 0.2 0.71 9.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.22 EGO26949.1 - 0.027 14.7 0.1 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter HLH PF00010.21 EGO26950.1 - 2.6e-11 43.0 0.0 5.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MoCF_biosynth PF00994.19 EGO26951.1 - 3.6e-33 113.9 0.0 5.8e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MCM PF00493.18 EGO26952.1 - 1.1e-131 438.6 0.0 1.4e-131 438.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO26952.1 - 3.3e-15 56.6 0.1 2.2e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EGO26952.1 - 7.8e-09 35.3 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO26952.1 - 4.6e-07 29.2 0.0 0.00038 19.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGO26952.1 - 3e-05 23.6 0.0 0.00058 19.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGO26952.1 - 0.003 17.0 0.0 4.2 6.8 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain RPA_C PF08784.6 EGO26952.1 - 0.017 15.5 0.1 0.05 14.0 0.0 1.8 1 0 0 1 1 1 0 Replication protein A C terminal Sigma54_activ_2 PF14532.1 EGO26952.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.1 EGO26952.1 - 0.14 10.8 1.6 0.37 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain ORC3_N PF07034.6 EGO26953.1 - 2.4e-30 105.6 0.9 7.7e-30 103.9 0.6 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus GPI-anchored PF10342.4 EGO26954.1 - 5.2e-09 36.4 0.9 1.1e-08 35.3 0.7 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hist_deacetyl PF00850.14 EGO26955.1 - 1.6e-92 310.1 0.0 2.5e-92 309.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EGO26955.1 - 3e-21 75.6 0.0 4.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain SAC3_GANP PF03399.11 EGO26956.1 - 7e-21 74.7 0.1 9.5e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGO26956.1 - 7.2e-21 74.4 0.0 1.7e-20 73.2 0.0 1.6 1 1 1 2 2 2 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 EGO26957.1 - 7e-43 146.0 1.3 1.4e-42 145.0 0.9 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGO26957.1 - 2.7e-13 50.1 1.8 4.3e-13 49.4 0.3 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGO26957.1 - 0.028 14.1 0.3 0.064 13.0 0.2 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 PP2C PF00481.16 EGO26958.1 - 5.2e-27 94.8 0.0 4.1e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGO26958.1 - 4e-06 26.3 0.0 7.1e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C Asn_synthase PF00733.16 EGO26959.1 - 6.1e-53 179.9 0.0 3.8e-52 177.3 0.0 1.9 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGO26959.1 - 1.9e-38 130.9 0.0 3.2e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGO26959.1 - 1.1e-32 112.8 0.0 2.8e-32 111.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGO26959.1 - 1.3e-06 27.7 0.0 2.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EGO26959.1 - 0.0019 16.9 0.0 0.075 11.7 0.0 2.6 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EGO26959.1 - 0.016 14.0 0.0 0.05 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD synthase Abhydrolase_3 PF07859.8 EGO26960.1 - 1.3e-22 80.4 0.0 1.9e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO26960.1 - 1.4e-05 23.9 0.0 3.7e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO26960.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO26960.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SepZ PF06066.6 EGO26961.1 - 0.14 12.1 1.9 8.3 6.4 0.0 2.7 1 1 1 2 2 2 0 SepZ DUF4131 PF13567.1 EGO26961.1 - 1.1 8.6 7.1 2.2 7.6 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1469 PF07332.6 EGO26961.1 - 2.5 7.8 7.2 1.5 8.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) zf-C2H2_4 PF13894.1 EGO26963.1 - 0.14 12.5 5.7 0.075 13.4 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger gag-asp_proteas PF13975.1 EGO26965.1 - 0.00069 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EGO26965.1 - 0.0011 18.7 4.2 0.0019 18.0 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26965.1 - 0.0058 16.6 0.2 0.015 15.3 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4381 PF14316.1 EGO26966.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4219 PF13961.1 EGO26968.1 - 0.0036 16.6 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EGO26968.1 - 0.02 14.4 0.3 0.031 13.8 0.2 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4351 PF14261.1 EGO26968.1 - 0.22 11.4 1.0 3.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) Isy1 PF06246.7 EGO26970.1 - 3.6e-78 262.4 2.1 6.3e-78 261.7 1.4 1.5 1 1 0 1 1 1 1 Isy1-like splicing family DUF605 PF04652.11 EGO26970.1 - 0.08 12.3 10.0 0.1 11.9 6.9 1.1 1 0 0 1 1 1 0 Vta1 like P22_Tail-4 PF11650.3 EGO26970.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor Macoilin PF09726.4 EGO26970.1 - 7.2 4.7 6.0 1.4 7.0 1.6 1.6 2 0 0 2 2 2 0 Transmembrane protein Sugar_tr PF00083.19 EGO26971.1 - 2.3e-112 375.8 28.3 2.6e-112 375.6 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO26971.1 - 1.2e-23 83.4 28.5 1.2e-23 83.4 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily N2227 PF07942.7 EGO26972.1 - 2.7e-97 324.9 0.0 4.7e-97 324.1 0.0 1.4 2 0 0 2 2 2 1 N2227-like protein Methyltransf_23 PF13489.1 EGO26972.1 - 8.8e-07 28.7 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO26972.1 - 0.0015 18.9 0.1 0.03 14.7 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO26972.1 - 0.045 14.2 0.0 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PP2C PF00481.16 EGO26973.1 - 2.2e-26 92.7 0.0 4.3e-24 85.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGO26973.1 - 0.051 13.2 0.0 5.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.20 EGO26974.1 - 3.9e-46 157.2 0.0 5.5e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO26974.1 - 2.1e-43 148.2 0.0 2.9e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO26974.1 - 1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO26974.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_transf_90 PF05686.7 EGO26975.1 - 2.8e-12 46.0 4.4 6.2e-11 41.6 3.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 Cauli_VI PF01693.11 EGO26975.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Caulimovirus viroplasmin DUF1054 PF06335.7 EGO26975.1 - 0.13 11.8 0.2 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Molybdopterin PF00384.17 EGO26977.1 - 5.1e-70 236.3 0.0 3.4e-69 233.6 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EGO26977.1 - 4.4e-19 68.0 0.2 1.1e-18 66.7 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EGO26977.1 - 4.5e-19 67.3 0.1 1.3e-18 65.9 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EGO26977.1 - 5.2e-16 58.5 0.2 1.2e-15 57.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EGO26977.1 - 3.5e-08 33.0 0.6 3.5e-08 33.0 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EGO26977.1 - 0.058 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain TPP_enzyme_M PF00205.17 EGO26977.1 - 0.065 12.9 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EGO26977.1 - 0.083 12.5 1.1 4 7.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EGO26977.1 - 0.25 11.2 2.4 0.46 10.4 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ABC2_membrane PF01061.19 EGO26978.1 - 1.2e-76 256.5 52.3 3.7e-44 150.4 13.5 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGO26978.1 - 4.5e-37 127.4 0.0 1.4e-18 67.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGO26978.1 - 8.2e-37 124.9 1.9 1.1e-29 102.1 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EGO26978.1 - 3.9e-10 39.6 0.0 9.1e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGO26978.1 - 1.6e-08 34.2 0.0 5.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGO26978.1 - 1.3e-06 27.6 0.0 2.4e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO26978.1 - 2.4e-06 27.6 0.0 0.0017 18.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO26978.1 - 5.4e-06 26.5 0.0 0.025 14.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO26978.1 - 2e-05 24.0 0.1 0.0041 16.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EGO26978.1 - 3.7e-05 23.4 0.0 0.0071 16.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 EGO26978.1 - 9.4e-05 23.2 0.0 0.092 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO26978.1 - 0.00018 21.8 0.0 0.083 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGO26978.1 - 0.00037 19.6 26.6 0.00037 19.6 18.4 3.8 3 2 1 4 4 4 1 ABC-2 family transporter protein AAA_33 PF13671.1 EGO26978.1 - 0.00044 20.1 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EGO26978.1 - 0.00078 19.0 0.1 0.035 13.7 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EGO26978.1 - 0.0015 18.4 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGO26978.1 - 0.0043 16.5 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 EGO26978.1 - 0.0044 17.0 0.0 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGO26978.1 - 0.0082 15.8 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 EGO26978.1 - 0.0084 15.8 0.7 0.59 9.9 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain cobW PF02492.14 EGO26978.1 - 0.01 15.2 0.2 0.13 11.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EGO26978.1 - 0.014 14.8 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EGO26978.1 - 0.018 14.9 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGO26978.1 - 0.024 13.5 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EGO26978.1 - 0.024 14.9 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EGO26978.1 - 0.031 14.7 0.0 4.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein AAA_30 PF13604.1 EGO26978.1 - 0.046 13.3 0.1 0.56 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGO26978.1 - 0.066 13.4 0.0 3 8.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGO26978.1 - 0.095 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EGO26978.1 - 0.1 12.5 0.0 24 4.9 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EGO26978.1 - 0.12 12.5 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EGO26978.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 EGO26978.1 - 0.22 10.2 0.0 5.9 5.5 0.1 2.3 2 0 0 2 2 2 0 ArgK protein ABC_ATPase PF09818.4 EGO26978.1 - 0.23 10.0 0.5 0.38 9.2 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Septin PF00735.13 EGO26978.1 - 0.25 10.3 0.0 2.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EGO26978.1 - 0.26 10.7 0.1 0.96 8.9 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation adh_short_C2 PF13561.1 EGO26983.1 - 6.5e-33 114.4 0.6 9.1e-33 114.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO26983.1 - 6.9e-31 107.4 0.3 1.2e-30 106.6 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO26983.1 - 1.3e-18 67.3 0.2 3.2e-18 66.0 0.1 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EGO26983.1 - 0.0023 17.4 0.2 0.003 17.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EGO26983.1 - 0.0097 15.3 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.1 EGO26983.1 - 0.01 15.8 0.1 0.034 14.1 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 EGO26983.1 - 0.048 13.3 0.1 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGO26983.1 - 0.061 13.7 1.0 2 8.9 0.0 2.9 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF4170 PF13773.1 EGO26983.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) Cation_efflux PF01545.16 EGO26984.1 - 6.7e-11 41.7 1.8 1.2e-10 40.9 1.3 1.4 1 0 0 1 1 1 1 Cation efflux family GMC_oxred_N PF00732.14 EGO26987.1 - 8.2e-57 192.6 0.0 1.4e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO26987.1 - 1.3e-34 119.5 0.0 3e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Nyv1_N PF09426.5 EGO26987.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Sugar_tr PF00083.19 EGO26988.1 - 7.9e-96 321.3 21.8 1.2e-95 320.7 15.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO26988.1 - 1.1e-21 76.9 38.6 5.5e-16 58.2 4.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO26989.1 - 1.7e-96 323.5 17.2 7.7e-96 321.4 11.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO26989.1 - 2.5e-24 85.6 28.6 1.1e-16 60.4 2.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO26989.1 - 0.0025 16.0 2.3 0.0025 16.0 1.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EGO26989.1 - 0.0081 14.3 7.9 0.01 14.0 1.9 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector DUF1228 PF06779.9 EGO26989.1 - 0.022 14.7 5.3 0.58 10.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) NADH_dehy_S2_C PF06444.6 EGO26989.1 - 0.078 13.2 0.4 0.078 13.2 0.3 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus zf-CCHC PF00098.18 EGO26992.1 - 0.00089 19.0 4.2 0.0016 18.2 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO26992.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein PTPA PF03095.10 EGO26994.1 - 3.2e-116 387.7 0.0 3.9e-116 387.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RAP1 PF07218.6 EGO26995.1 - 0.026 12.6 0.0 0.029 12.4 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) COG5 PF10392.4 EGO26995.1 - 0.03 14.2 1.2 0.087 12.7 0.2 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 OEP PF02321.13 EGO26995.1 - 0.037 13.6 4.2 0.23 11.0 0.6 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein MbeD_MobD PF04899.7 EGO26995.1 - 0.34 10.8 3.3 1.3 9.0 0.4 2.6 2 1 0 2 2 2 0 MbeD/MobD like CNF1 PF05785.7 EGO26996.1 - 0.0038 16.1 0.5 0.007 15.2 0.1 1.6 2 0 0 2 2 2 1 Rho-activating domain of cytotoxic necrotizing factor Myb_DNA-bind_4 PF13837.1 EGO27001.1 - 0.0028 17.7 0.0 0.022 14.8 0.0 2.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EGO27001.1 - 0.0076 16.8 0.1 0.022 15.3 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1997 PF09366.5 EGO27001.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1997) DZR PF12773.2 EGO27004.1 - 0.13 12.1 3.5 0.31 10.8 2.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C4pol PF14260.1 EGO27004.1 - 0.16 11.9 2.8 0.27 11.2 0.5 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC_3 PF13917.1 EGO27004.1 - 0.18 11.5 3.7 0.54 10.0 2.5 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-ribbon_3 PF13248.1 EGO27004.1 - 0.28 10.4 5.9 0.96 8.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGO27004.1 - 0.48 9.9 3.5 0.66 9.5 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 EGO27004.1 - 1.4 8.4 5.1 2.7 7.5 3.5 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DKNYY PF13644.1 EGO27005.1 - 0.029 14.6 0.7 0.031 14.5 0.5 1.1 1 0 0 1 1 1 0 DKNYY family DDE_1 PF03184.14 EGO27007.1 - 4.4e-10 39.0 7.6 8.1e-09 34.9 2.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EGO27008.1 - 0.027 14.2 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain ARA70 PF12489.3 EGO27008.1 - 0.07 13.1 0.2 0.09 12.7 0.1 1.2 1 0 0 1 1 1 0 Nuclear coactivator Retrotrans_gag PF03732.12 EGO27010.1 - 7.8e-05 22.6 0.5 0.00099 19.1 0.0 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein DUF3723 PF12520.3 EGO27010.1 - 0.021 13.3 0.4 0.028 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) PIF1 PF05970.9 EGO27022.1 - 3.1e-06 26.3 0.9 8.3e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EGO27022.1 - 0.00095 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO27022.1 - 0.0075 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AMP-binding PF00501.23 EGO27024.1 - 1.5e-65 221.2 0.0 9.6e-42 142.8 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EGO27024.1 - 1.8e-05 25.5 0.0 6.5e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DDE_1 PF03184.14 EGO27025.1 - 0.00052 19.2 0.0 0.00054 19.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.12 EGO27026.1 - 1.2e-06 28.5 0.0 4.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EGO27027.1 - 4.2e-06 26.4 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO27027.1 - 0.00015 22.1 0.0 0.00038 20.8 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 EGO27027.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Rogdi_lz PF10259.4 EGO27027.1 - 0.088 11.9 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein GMC_oxred_N PF00732.14 EGO27028.1 - 4.4e-64 216.4 0.0 5.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO27028.1 - 4e-32 111.5 0.0 8.1e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EGO27028.1 - 0.00017 20.6 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Hydrophobin PF01185.13 EGO27029.1 - 3.3e-24 85.1 8.3 4.8e-24 84.6 5.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 EGO27029.1 - 9 6.8 8.8 13 6.3 0.4 2.5 2 0 0 2 2 2 0 Ion channel inhibitory toxin AA_permease PF00324.16 EGO27031.1 - 8e-102 341.0 42.5 1e-101 340.6 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO27031.1 - 2e-29 102.4 47.4 4.3e-29 101.3 32.2 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO27032.1 - 1.6e-100 336.7 49.3 2e-100 336.4 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO27032.1 - 1.5e-24 86.3 52.9 2e-24 85.9 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease Halogen_Hydrol PF10112.4 EGO27032.1 - 0.16 11.3 0.4 0.71 9.2 0.3 2.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HAD PF12710.2 EGO27033.1 - 1.9e-20 73.8 0.1 5.4e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGO27033.1 - 5e-18 64.9 0.0 1.5e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGO27033.1 - 3.7e-14 53.6 3.8 5.8e-13 49.7 2.7 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO27033.1 - 4e-13 49.1 0.0 1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO27033.1 - 0.0041 16.7 0.6 0.012 15.1 0.1 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.16 EGO27034.1 - 1e-43 149.2 0.1 1.5e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EGO27034.1 - 3.5e-07 29.7 3.7 0.00032 20.2 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO27034.1 - 0.00044 19.9 2.9 0.18 11.7 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO27034.1 - 0.0008 18.9 2.0 0.16 11.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Exo_endo_phos PF03372.18 EGO27036.1 - 5.1e-05 23.3 0.0 0.0002 21.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EGO27037.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Glyco_transf_10 PF00852.14 EGO27037.1 - 0.09 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) HNOBA PF07701.9 EGO27038.1 - 0.017 14.3 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding associated SPO11_like PF03533.9 EGO27038.1 - 0.081 12.8 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 SPO11 homologue F-box-like PF12937.2 EGO27043.1 - 2.2e-05 24.0 2.8 3.9e-05 23.2 0.4 2.7 2 0 0 2 2 2 1 F-box-like TM2 PF05154.11 EGO27044.1 - 0.11 12.7 0.8 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 TM2 domain Abhydrolase_6 PF12697.2 EGO27047.1 - 4e-29 102.1 0.0 6.2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO27047.1 - 1.4e-16 60.7 1.0 8.3e-16 58.2 0.3 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO27047.1 - 1.4e-08 34.5 0.0 2e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EGO27047.1 - 6.5e-05 21.5 0.0 9.1e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EGO27047.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 EGO27047.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UNC45-central PF11701.3 EGO27048.1 - 1.9e-12 47.1 0.0 6.1e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EGO27048.1 - 0.0053 16.5 0.9 13 5.7 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGO27048.1 - 5.4 7.3 7.8 5.8 7.2 0.1 4.5 5 0 0 5 5 5 0 HEAT repeat zf-CCHC_6 PF15288.1 EGO27049.1 - 0.0072 15.9 0.6 0.017 14.7 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF1279 PF06916.8 EGO27049.1 - 0.15 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DUF605 PF04652.11 EGO27051.1 - 0.0066 15.8 9.4 0.0076 15.6 6.5 1.2 1 0 0 1 1 1 1 Vta1 like Nop14 PF04147.7 EGO27051.1 - 0.061 11.2 7.8 0.078 10.8 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EGO27051.1 - 0.11 11.4 12.6 0.16 10.9 8.7 1.3 1 0 0 1 1 1 0 BUD22 DUF4551 PF15087.1 EGO27051.1 - 7 4.8 7.2 11 4.2 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DNA_binding_1 PF01035.15 EGO27052.1 - 3.9e-23 80.9 0.0 1.8e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Deltaretro_Tax PF05599.6 EGO27052.1 - 0.028 14.7 0.2 0.081 13.2 0.2 1.8 1 1 0 1 1 1 0 Deltaretrovirus Tax protein Apolipoprotein PF01442.13 EGO27053.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1469 PF07332.6 EGO27053.1 - 1.8 8.3 8.0 15 5.3 5.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) TAXi_C PF14541.1 EGO27055.1 - 0.034 13.6 0.0 0.038 13.5 0.0 1.0 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DDE_3 PF13358.1 EGO27057.1 - 2.7e-11 43.3 0.0 6.7e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2183 PF09949.4 EGO27057.1 - 0.041 13.8 0.1 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Peptidase_S10 PF00450.17 EGO27058.1 - 2e-81 274.3 0.0 2.5e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SNO PF01174.14 EGO27059.1 - 4.7e-47 160.0 0.0 7.7e-45 152.8 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGO27059.1 - 9.6e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EGO27059.1 - 1.4e-05 24.4 0.1 2.3e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EGO27059.1 - 0.00046 19.9 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.23 EGO27059.1 - 0.001 18.5 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EGO27059.1 - 0.002 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MutH PF02976.10 EGO27060.1 - 0.016 15.0 0.1 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 DNA mismatch repair enzyme MutH PAT1 PF09770.4 EGO27060.1 - 1.5 6.9 11.6 1.6 6.8 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 EGO27061.1 - 8.1e-17 60.6 0.0 8.4e-17 60.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27061.1 - 8.7e-15 54.4 0.0 9e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27061.1 - 6.1e-07 29.1 0.0 6.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_U5 PF05999.6 EGO27063.1 - 0.062 11.8 0.2 0.069 11.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family DUF4211 PF13926.1 EGO27063.1 - 0.15 11.4 0.1 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Ribosomal_L32p PF01783.18 EGO27064.1 - 0.77 9.9 7.0 0.15 12.2 2.4 1.6 2 0 0 2 2 2 0 Ribosomal L32p protein family Anoctamin PF04547.7 EGO27066.1 - 4.1e-95 319.0 0.0 6.2e-95 318.5 0.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3870 PF12986.2 EGO27066.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Se-cys_synth_N PF12390.3 EGO27066.1 - 0.15 12.1 1.6 0.29 11.2 0.2 2.1 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Suf PF05843.9 EGO27069.1 - 5.6e-74 249.3 0.0 4.3e-71 239.9 0.0 3.6 3 2 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGO27069.1 - 3.3e-11 42.7 6.8 0.018 15.6 0.0 7.4 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO27069.1 - 5.7e-10 39.3 0.3 0.059 13.7 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO27069.1 - 5.9e-05 23.6 7.4 0.052 14.2 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO27069.1 - 9.3e-05 22.6 1.2 0.24 11.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO27069.1 - 0.018 15.2 1.0 11 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FTCD_C PF04961.7 EGO27069.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase TPR_11 PF13414.1 EGO27069.1 - 0.071 12.7 3.2 17 5.1 0.1 3.9 4 0 0 4 4 4 0 TPR repeat DUF1180 PF06679.7 EGO27069.1 - 0.92 9.3 6.7 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Mad3_BUB1_I PF08311.7 EGO27069.1 - 7.5 6.3 10.3 1.2 8.9 0.1 3.8 3 2 1 4 4 4 0 Mad3/BUB1 homology region 1 Glyco_hydro_85 PF03644.8 EGO27070.1 - 3.5e-76 256.3 0.0 5e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 bZIP_1 PF00170.16 EGO27072.1 - 0.0018 18.1 1.2 0.0018 18.1 0.8 2.5 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EGO27072.1 - 0.12 12.1 4.4 0.073 12.9 1.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EGO27072.1 - 4 6.9 10.4 3.5 7.1 0.1 2.6 2 1 0 2 2 2 0 IncA protein TBPIP PF07106.8 EGO27072.1 - 6.8 6.2 7.5 18 4.8 0.3 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RFC1 PF08519.7 EGO27073.1 - 1.4e-52 177.6 0.0 4.9e-51 172.5 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EGO27073.1 - 1.2e-11 44.6 0.0 3e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EGO27073.1 - 5.7e-08 33.0 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGO27073.1 - 0.0016 17.1 0.3 0.0085 14.8 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGO27073.1 - 0.015 15.0 0.0 0.046 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EGO27073.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO27073.1 - 0.052 13.6 0.1 0.24 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EGO27073.1 - 0.085 11.8 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EGO27073.1 - 0.089 12.4 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EGO27073.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.11 EGO27074.1 - 2.5e-15 56.0 22.2 2.5e-15 56.0 15.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EGO27074.1 - 1.7e-11 43.8 2.6 4.4e-11 42.5 1.8 1.7 1 0 0 1 1 1 1 Nodulin-like Tcf25 PF04910.9 EGO27075.1 - 3e-75 253.4 0.1 5.1e-75 252.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_10 PF13374.1 EGO27075.1 - 0.0054 16.6 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO27075.1 - 0.0066 16.3 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2413 PF10310.4 EGO27075.1 - 4.7 5.9 15.9 7.9 5.1 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) p450 PF00067.17 EGO27076.1 - 1.5e-70 237.9 0.0 1.1e-69 235.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO27077.1 - 8.6e-65 219.0 0.0 2.4e-64 217.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Dicty_REP PF05086.7 EGO27078.1 - 0.00011 20.1 2.6 0.00013 19.9 1.8 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Paf1 PF03985.8 EGO27078.1 - 0.28 9.8 18.2 0.36 9.5 12.6 1.1 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 EGO27078.1 - 3 7.1 21.4 4.1 6.7 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mem_trans PF03547.13 EGO27078.1 - 4.5 5.4 5.1 5.6 5.1 3.6 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF1682 PF07946.9 EGO27078.1 - 5.9 5.6 18.2 7.1 5.3 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UBN2_3 PF14244.1 EGO27079.1 - 9.6e-06 25.2 0.1 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO27079.1 - 0.00058 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO27079.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Homeobox PF00046.24 EGO27080.1 - 0.0089 15.6 0.3 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Spc7 PF08317.6 EGO27080.1 - 0.029 13.0 2.3 0.035 12.7 1.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PXA PF02194.10 EGO27080.1 - 0.03 13.8 0.2 0.03 13.8 0.2 1.0 1 0 0 1 1 1 0 PXA domain Phage_GPO PF05929.6 EGO27080.1 - 0.045 12.9 3.8 0.048 12.9 2.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.1 EGO27080.1 - 0.072 12.0 1.7 0.078 11.9 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KLRAQ PF10205.4 EGO27080.1 - 0.15 12.1 4.6 0.15 12.0 3.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein ACCA PF03255.9 EGO27080.1 - 0.16 11.5 1.3 0.18 11.3 0.9 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Tup_N PF08581.5 EGO27080.1 - 0.16 12.1 6.0 0.24 11.6 4.1 1.3 1 0 0 1 1 1 0 Tup N-terminal Phage_Gp23 PF10669.4 EGO27080.1 - 0.21 11.7 6.0 0.23 11.5 4.1 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Fib_alpha PF08702.5 EGO27080.1 - 0.28 11.2 4.5 0.33 11.0 3.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V-ATPase_G PF03179.10 EGO27080.1 - 0.37 11.1 5.3 0.45 10.8 3.7 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TPR_MLP1_2 PF07926.7 EGO27080.1 - 1 9.0 7.8 0.51 10.0 1.5 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein RBD-FIP PF09457.5 EGO27080.1 - 5.3 6.9 5.8 1 9.2 0.8 2.1 3 0 0 3 3 3 0 FIP domain DUF3678 PF12435.3 EGO27082.1 - 0.11 12.0 0.5 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) IMPDH PF00478.20 EGO27083.1 - 2.8e-107 358.6 1.0 1.7e-70 237.6 0.0 2.9 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGO27083.1 - 1.5e-16 59.9 0.2 2.8e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EGO27083.1 - 0.0035 16.2 4.4 0.43 9.3 3.2 2.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EGO27083.1 - 0.017 14.3 8.8 2.8 7.0 4.3 3.0 2 1 0 2 2 2 0 Nitronate monooxygenase Aldolase PF01081.14 EGO27083.1 - 0.069 12.3 0.8 0.28 10.3 0.4 2.1 2 1 0 2 2 2 0 KDPG and KHG aldolase HK PF02110.10 EGO27083.1 - 0.11 11.6 4.0 0.35 10.0 0.1 2.5 2 1 0 3 3 3 0 Hydroxyethylthiazole kinase family F-box-like PF12937.2 EGO27084.1 - 1.5e-06 27.8 0.4 3.9e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO27084.1 - 0.00075 19.0 0.2 0.002 17.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain TIR PF01582.15 EGO27086.1 - 0.0018 17.6 0.4 0.0048 16.3 0.1 1.7 2 0 0 2 2 2 1 TIR domain Bactofilin PF04519.8 EGO27087.1 - 0.052 13.5 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Polymer-forming cytoskeletal zf-C2H2 PF00096.21 EGO27094.1 - 1.3e-13 50.3 9.9 9.8e-07 28.7 3.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO27094.1 - 2.7e-10 39.8 10.7 5.7e-05 23.1 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO27094.1 - 1.7e-09 37.4 14.2 1.9e-06 27.8 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 EGO27094.1 - 4.3e-05 23.0 11.9 0.0013 18.3 1.8 2.6 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EGO27094.1 - 0.00012 22.0 4.9 0.00045 20.2 0.5 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EGO27094.1 - 0.0043 17.3 1.8 0.0055 17.0 1.3 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger zf-met PF12874.2 EGO27094.1 - 0.0048 17.0 1.8 0.0048 17.0 1.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.1 EGO27094.1 - 0.0057 16.2 0.2 0.17 11.5 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2H2_6 PF13912.1 EGO27094.1 - 0.0062 16.3 1.6 0.032 14.1 0.2 2.3 2 1 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 EGO27094.1 - 0.008 15.8 0.3 0.21 11.3 0.2 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-Di19 PF05605.7 EGO27094.1 - 0.0092 16.0 5.4 0.044 13.8 3.7 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.1 EGO27094.1 - 0.018 14.9 0.3 0.18 11.7 0.2 1.9 1 1 0 1 1 1 0 CpXC protein Zn-ribbon_8 PF09723.5 EGO27094.1 - 0.019 14.9 1.3 4.1 7.4 0.4 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_5 PF13909.1 EGO27094.1 - 0.049 13.8 2.8 0.049 13.8 1.9 2.5 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-ribbon_3 PF13248.1 EGO27094.1 - 0.16 11.2 3.1 0.45 9.7 0.1 2.3 2 1 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 EGO27094.1 - 0.25 11.3 5.5 2 8.5 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_2 PF12756.2 EGO27094.1 - 0.33 11.0 2.3 0.61 10.2 0.4 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) IBR PF01485.16 EGO27094.1 - 0.37 10.6 2.6 1.7 8.5 0.0 2.0 1 1 1 2 2 2 0 IBR domain zf-CSL PF05207.8 EGO27094.1 - 0.42 10.1 2.3 7 6.2 0.2 2.3 2 1 0 2 2 2 0 CSL zinc finger FYDLN_acid PF09538.5 EGO27094.1 - 0.91 10.1 2.6 6.1 7.4 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-BED PF02892.10 EGO27094.1 - 0.94 9.2 7.3 3.2 7.5 1.7 2.2 2 0 0 2 2 2 0 BED zinc finger PAN_2 PF08276.6 EGO27099.1 - 0.0014 18.4 3.3 0.002 17.9 2.3 1.3 1 0 0 1 1 1 1 PAN-like domain DUF1129 PF06570.6 EGO27100.1 - 1.2 8.3 7.4 2.6 7.3 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PNP_UDP_1 PF01048.15 EGO27101.1 - 1.6e-29 102.5 0.0 2e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Laminin_G_3 PF13385.1 EGO27103.1 - 3e-13 50.3 8.8 3.8e-10 40.2 0.0 3.0 3 1 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EGO27103.1 - 0.0028 17.6 0.1 2.2 8.3 0.0 3.0 3 0 0 3 3 3 2 Laminin G domain DUF4473 PF14747.1 EGO27104.1 - 0.0012 18.9 0.2 0.0022 18.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Phage_head_chap PF11113.3 EGO27104.1 - 0.053 13.4 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Head assembly gene product PB1 PF00564.19 EGO27104.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PB1 domain gag-asp_proteas PF13975.1 EGO27106.1 - 2.6e-08 33.5 0.0 3.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO27106.1 - 4.5e-07 30.2 0.0 5.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO27106.1 - 4.7e-06 26.5 0.0 5.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EGO27106.1 - 0.059 13.2 0.2 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 EGO27109.1 - 0.11 12.4 0.2 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PRKCSH-like PF12999.2 EGO27110.1 - 1.8e-49 167.6 0.5 5.1e-49 166.2 0.4 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EGO27110.1 - 8.7e-24 83.7 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EGO27110.1 - 1.5e-10 41.7 0.9 3.9e-10 40.4 0.4 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EGO27110.1 - 0.78 9.6 17.0 0.33 10.9 2.7 2.6 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Ribosomal_S25 PF03297.10 EGO27111.1 - 1e-40 137.9 0.6 1.1e-40 137.8 0.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EGO27111.1 - 0.0011 18.3 0.3 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF505 PF04458.7 EGO27111.1 - 0.0081 14.3 0.0 0.0094 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF505) MarR PF01047.17 EGO27111.1 - 0.0094 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 MarR family MerR PF00376.18 EGO27111.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein GntR PF00392.16 EGO27111.1 - 0.084 12.3 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR_2 PF12802.2 EGO27111.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 MarR family FGGY_C PF02782.11 EGO27112.1 - 1.6e-47 161.7 0.0 2.5e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGO27112.1 - 1.6e-20 73.4 0.2 6.8e-20 71.4 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CmcH_NodU PF02543.10 EGO27112.1 - 0.0012 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyltransferase BcrAD_BadFG PF01869.15 EGO27112.1 - 0.0074 15.6 1.0 0.15 11.3 0.2 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FYRC PF05965.9 EGO27112.1 - 0.089 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 F/Y rich C-terminus Ribosomal_L2_C PF03947.13 EGO27113.1 - 4.8e-41 139.5 1.8 8.1e-41 138.8 1.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGO27113.1 - 1.7e-13 50.2 0.1 3.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Neur_chan_memb PF02932.11 EGO27114.1 - 4.5 7.0 15.2 4.6 7.0 1.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SH3_9 PF14604.1 EGO27115.1 - 8.7e-13 47.6 0.0 1.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO27115.1 - 4.1e-12 45.2 0.1 6.6e-12 44.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO27115.1 - 3.4e-11 42.4 0.0 5.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ATP-synt_C PF00137.16 EGO27115.1 - 0.14 12.0 1.7 0.36 10.7 1.2 1.7 1 0 0 1 1 1 0 ATP synthase subunit C UAA PF08449.6 EGO27116.1 - 3.9e-23 81.8 2.2 4e-23 81.7 1.5 1.0 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGO27116.1 - 0.025 14.7 1.1 0.026 14.6 0.8 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter EamA PF00892.15 EGO27116.1 - 0.027 14.5 1.1 0.029 14.3 0.8 1.0 1 0 0 1 1 1 0 EamA-like transporter family Multi_Drug_Res PF00893.14 EGO27116.1 - 0.18 12.2 1.9 0.22 12.0 1.3 1.1 1 0 0 1 1 1 0 Small Multidrug Resistance protein MIF4G_like PF09088.6 EGO27117.1 - 1.8e-60 203.6 0.0 3.4e-60 202.7 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EGO27117.1 - 8.7e-35 120.1 0.0 1.4e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EGO27117.1 - 0.0096 15.3 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain DUF2363 PF10155.4 EGO27117.1 - 0.21 11.5 0.4 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) HEAT_2 PF13646.1 EGO27119.1 - 0.053 13.8 0.3 0.28 11.4 0.1 2.2 2 1 0 2 2 2 0 HEAT repeats PPR_3 PF13812.1 EGO27120.1 - 0.0038 17.3 0.3 8.5 6.9 0.0 4.6 4 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGO27120.1 - 0.03 14.3 0.0 5.6 7.0 0.0 3.6 4 0 0 4 4 4 0 PPR repeat family PPR_1 PF12854.2 EGO27120.1 - 0.035 13.6 0.2 0.61 9.6 0.1 2.6 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 EGO27120.1 - 0.13 12.2 1.5 2 8.5 0.0 3.5 4 0 0 4 4 4 0 PPR repeat Mito_carr PF00153.22 EGO27121.1 - 3.6e-63 209.3 2.8 3.2e-21 74.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MGC-24 PF05283.6 EGO27123.1 - 3.4 7.4 15.6 5.2 6.8 10.8 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Med3 PF11593.3 EGO27123.1 - 8.7 5.4 11.2 15 4.7 7.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Acyl-CoA_dh_1 PF00441.19 EGO27124.1 - 9e-31 106.9 0.6 1.4e-30 106.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO27124.1 - 3.6e-20 71.2 1.7 1e-19 69.7 1.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EGO27124.1 - 3.3e-17 62.0 0.1 1.2e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EGO27124.1 - 7.5e-13 49.0 0.0 3e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO27124.1 - 3e-06 27.5 0.2 5.4e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.18 EGO27125.1 - 3.5e-66 223.0 0.1 5.2e-66 222.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO27125.1 - 6.7e-12 45.1 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO27125.1 - 1e-06 28.7 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO27125.1 - 2.1e-06 27.3 0.0 5.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EGO27125.1 - 6.2e-06 25.9 4.8 6.2e-06 25.9 3.3 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO27125.1 - 9.6e-06 25.5 4.1 9.6e-06 25.5 2.8 2.8 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO27125.1 - 1e-05 25.0 3.8 1e-05 25.0 2.6 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EGO27125.1 - 0.0003 20.2 2.8 0.00078 18.9 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EGO27125.1 - 0.00094 19.2 0.6 0.00094 19.2 0.4 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO27125.1 - 0.0012 18.4 3.2 0.0012 18.4 2.2 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGO27125.1 - 0.0068 16.1 1.4 0.019 14.7 1.0 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGO27125.1 - 0.0073 16.1 0.7 0.021 14.6 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD_2 PF06733.10 EGO27125.1 - 0.64 9.3 3.1 0.54 9.6 0.1 2.4 3 1 0 3 3 3 0 DEAD_2 F_bP_aldolase PF01116.15 EGO27126.1 - 2.9e-96 321.9 0.0 3.3e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 EGO27126.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Torsin Phage_min_cap2 PF06152.6 EGO27126.1 - 0.065 12.1 0.0 0.67 8.8 0.0 2.1 2 0 0 2 2 2 0 Phage minor capsid protein 2 CPSase_L_D2 PF02786.12 EGO27126.1 - 0.11 11.7 0.1 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain WW PF00397.21 EGO27128.1 - 0.014 15.2 2.2 0.014 15.2 1.5 2.1 2 0 0 2 2 2 0 WW domain RAP1 PF07218.6 EGO27129.1 - 9.9 4.1 11.5 12 3.8 8.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HMG_box PF00505.14 EGO27130.1 - 1.9e-18 66.4 2.2 2.2e-18 66.2 1.5 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO27130.1 - 3.1e-11 43.4 2.1 3.8e-11 43.1 1.5 1.1 1 0 0 1 1 1 1 HMG-box domain DUF1074 PF06382.6 EGO27130.1 - 0.018 14.9 0.1 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) CHDNT PF08073.7 EGO27130.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 EGO27130.1 - 0.027 14.7 0.1 0.18 12.0 0.0 1.9 1 1 1 2 2 2 0 YABBY protein Spt5_N PF11942.3 EGO27130.1 - 0.1 13.2 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Med26 PF08711.6 EGO27131.1 - 4e-08 32.6 0.2 7.2e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.19 EGO27131.1 - 8.5e-07 28.5 3.7 1.4e-06 27.8 2.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO27131.1 - 0.059 13.3 4.0 0.11 12.5 2.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type API5 PF05918.6 EGO27131.1 - 9.8 4.5 6.2 14 3.9 4.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S4 PF00163.14 EGO27132.1 - 8.5e-13 48.5 0.3 1.1e-12 48.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGO27132.1 - 3.2e-11 42.4 0.0 5.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 S4 domain Herpes_LAMP2 PF06126.6 EGO27132.1 - 0.14 10.5 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Kinesin PF00225.18 EGO27133.1 - 8.4e-97 323.8 0.2 1.4e-96 323.1 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EGO27133.1 - 4.3e-39 133.3 0.0 1e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EGO27133.1 - 1.7e-12 47.4 0.0 4.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 EGO27133.1 - 4e-08 33.1 0.4 1.1e-07 31.7 0.3 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EGO27133.1 - 2.9e-07 30.4 0.0 1.8e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 FHA domain LSR PF05624.9 EGO27134.1 - 0.07 12.8 0.8 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Arf PF00025.16 EGO27135.1 - 5.6e-70 234.1 0.6 6.4e-70 233.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGO27135.1 - 1e-13 50.7 1.2 1.1e-07 30.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO27135.1 - 3.1e-10 39.5 0.0 3.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGO27135.1 - 4.5e-09 35.7 0.0 6.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGO27135.1 - 5.1e-09 35.7 0.0 6.2e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EGO27135.1 - 5e-08 32.9 0.0 6.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO27135.1 - 1.5e-06 28.7 0.0 2.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EGO27135.1 - 0.00011 21.7 0.0 0.006 16.0 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGO27135.1 - 0.013 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EGO27135.1 - 0.05 13.4 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Peptidase_M24 PF00557.19 EGO27136.1 - 7.8e-38 130.1 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGO27136.1 - 4.1e-31 107.1 0.0 7.6e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Lipase_3 PF01764.20 EGO27137.1 - 3.9e-17 62.1 0.0 7.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGO27137.1 - 0.0028 17.4 0.0 0.018 14.7 0.0 2.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO27137.1 - 0.0097 15.8 0.6 0.025 14.4 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Spt4 PF06093.8 EGO27138.1 - 5.8e-29 99.8 0.1 7e-29 99.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger ATP-synt_S1 PF05827.7 EGO27139.1 - 1.4e-12 47.5 0.5 5.9e-11 42.1 0.0 2.0 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Med13_C PF06333.7 EGO27140.1 - 4.9e-20 71.4 0.0 4.9e-20 71.4 0.0 3.1 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal MerR PF00376.18 EGO27140.1 - 0.13 11.8 0.0 0.44 10.1 0.0 1.9 1 0 0 1 1 1 0 MerR family regulatory protein DUF2433 PF10360.4 EGO27141.1 - 5.1e-33 114.2 0.0 9.5e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 EGO27141.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO27141.1 - 0.00013 21.5 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 EGO27141.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MIP-T3 PF10243.4 EGO27141.1 - 0.5 8.7 25.0 0.74 8.2 17.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hex_IIIa PF02455.11 EGO27141.1 - 4.3 5.9 5.0 6.5 5.3 3.5 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Acyl-CoA_dh_1 PF00441.19 EGO27142.1 - 3.9e-44 150.3 2.9 5.8e-44 149.8 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO27142.1 - 6.6e-24 84.6 0.1 2.8e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO27142.1 - 2.1e-22 79.7 0.6 3.6e-22 79.0 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO27142.1 - 3.1e-19 68.2 0.2 7.2e-19 67.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Mito_carr PF00153.22 EGO27143.1 - 7.3e-15 54.4 0.1 7.9e-15 54.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein RhoGEF PF00621.15 EGO27144.1 - 4.1e-16 59.3 0.0 9.2e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain NosL PF05573.7 EGO27146.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 NosL RNA_pol_Rpb1_5 PF04998.12 EGO27147.1 - 6.6e-95 317.5 0.2 9.6e-95 316.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EGO27147.1 - 3.2e-89 299.5 0.0 4.7e-89 298.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EGO27147.1 - 1.9e-67 226.3 0.0 3.8e-67 225.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGO27147.1 - 1.7e-40 138.3 0.0 7e-39 133.0 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGO27147.1 - 6.9e-33 112.6 0.0 1.8e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EGO27147.1 - 0.013 14.9 0.2 0.033 13.6 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain Proteasome PF00227.21 EGO27148.1 - 7e-47 159.1 0.1 3.1e-46 157.0 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO27148.1 - 3.3e-15 55.0 0.4 6.2e-15 54.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GDI PF00996.13 EGO27149.1 - 1.3e-19 69.9 0.0 8.2e-19 67.2 0.0 2.1 3 0 0 3 3 3 1 GDP dissociation inhibitor Ric8 PF10165.4 EGO27150.1 - 6.5e-76 255.9 0.0 9.4e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.4 EGO27151.1 - 7.4e-19 67.8 0.1 1e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.1 EGO27151.1 - 0.0071 16.4 0.1 0.0095 16.0 0.0 1.2 1 0 0 1 1 1 1 PIN domain Snf7 PF03357.16 EGO27151.1 - 0.097 12.0 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Snf7 PMI_typeI PF01238.16 EGO27152.1 - 2.2e-117 392.2 0.0 2.6e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EGO27152.1 - 7.9e-06 25.2 0.0 0.0056 16.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EGO27152.1 - 2.2e-05 24.1 0.0 0.014 15.1 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EGO27152.1 - 0.0022 17.6 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.7 EGO27152.1 - 0.016 14.5 0.1 0.06 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Lipase_3 PF01764.20 EGO27153.1 - 1.7e-22 79.5 0.0 2.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGO27153.1 - 0.008 16.0 0.1 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO27153.1 - 0.016 14.7 0.2 0.031 13.8 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO27153.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family STE3 PF02076.10 EGO27154.1 - 2.5e-40 138.3 6.9 3e-40 138.0 4.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4381 PF14316.1 EGO27154.1 - 0.1 12.7 0.6 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Lipase_3 PF01764.20 EGO27155.1 - 1.8e-20 73.0 0.0 2.6e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGO27155.1 - 0.0029 17.5 0.1 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO27155.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPP_enzyme_C PF02775.16 EGO27155.1 - 0.12 11.9 1.1 0.5 9.9 0.0 2.4 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short_C2 PF13561.1 EGO27156.1 - 8.2e-28 97.7 0.1 1e-27 97.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO27156.1 - 4.9e-23 81.8 0.1 8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO27156.1 - 1.3e-08 34.6 0.1 3.6e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGO27156.1 - 0.0053 16.5 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EGO27156.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 EGO27156.1 - 0.019 14.0 0.1 0.087 11.9 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EF-hand_1 PF00036.27 EGO27159.1 - 8.3e-26 87.2 9.6 8.4e-06 24.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO27159.1 - 1.5e-24 85.8 2.0 3.4e-12 46.3 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO27159.1 - 1.3e-20 71.3 5.6 3.3e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGO27159.1 - 1.6e-18 65.1 8.9 5e-05 22.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGO27159.1 - 2.8e-15 55.6 10.2 7.7e-05 22.2 0.8 4.7 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGO27159.1 - 4e-06 26.8 0.0 0.0054 16.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGO27159.1 - 3.2e-05 23.6 5.2 0.0069 16.1 0.5 3.6 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand RST PF12174.3 EGO27159.1 - 0.13 12.0 0.5 0.35 10.7 0.1 1.8 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain TrmE_N PF10396.4 EGO27160.1 - 8.6e-34 115.9 0.0 1.8e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EGO27160.1 - 1.2e-19 70.4 0.0 3.3e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EGO27160.1 - 9.1e-16 57.8 0.0 2.7e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO27160.1 - 0.00027 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGO27160.1 - 0.00041 20.8 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGO27160.1 - 0.00044 20.1 0.6 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 EGO27160.1 - 0.0012 19.6 0.2 0.0042 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO27160.1 - 0.01 16.1 0.0 0.036 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGO27160.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGO27160.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO27160.1 - 0.12 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EGO27162.1 - 2.8e-13 49.1 19.7 7.2e-08 32.0 1.6 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EGO27162.1 - 4.5e-07 29.7 0.4 4.6e-05 23.2 0.1 3.3 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EGO27162.1 - 0.047 13.9 0.1 0.72 10.2 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain DUF2454 PF10521.4 EGO27163.1 - 6.2e-36 123.8 0.0 8.8e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) WD40 PF00400.27 EGO27166.1 - 1.6e-12 46.7 13.3 8.5e-05 22.2 0.3 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Fungal_trans PF04082.13 EGO27168.1 - 3.3e-11 42.5 0.5 5.7e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO27168.1 - 4.5e-06 26.4 11.1 8.1e-06 25.6 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT PF03062.14 EGO27169.1 - 1.3e-42 146.0 4.5 1.3e-42 146.0 3.1 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Bestrophin PF01062.16 EGO27170.1 - 3e-43 147.8 0.2 1.3e-26 93.2 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Ribosomal_L18e PF00828.14 EGO27171.1 - 3e-22 79.3 0.0 3e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 EGO27172.1 - 4.9e-17 61.3 0.0 6.8e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27172.1 - 8.9e-16 57.4 0.0 1.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27172.1 - 4.4e-15 55.4 0.0 6.6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MalM PF07148.7 EGO27175.1 - 0.084 12.3 0.0 0.086 12.2 0.0 1.0 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) Acyl-ACP_TE PF01643.12 EGO27178.1 - 0.037 12.9 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase zf-RVT PF13966.1 EGO27178.1 - 0.068 13.4 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase SNAPc19 PF15497.1 EGO27179.1 - 0.1 12.7 0.7 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 ADH_N PF08240.7 EGO27183.1 - 0.018 14.8 0.2 0.08 12.7 0.1 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain TFIIE-A_C-term PF11521.3 EGO27183.1 - 0.48 10.4 4.0 0.31 11.0 0.1 2.4 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Retrotrans_gag PF03732.12 EGO27184.1 - 4.9e-07 29.7 2.0 4.9e-07 29.7 1.4 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein JmjC PF02373.17 EGO27185.1 - 7.9e-14 51.8 0.0 1.9e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EGO27185.1 - 0.00018 21.0 0.1 0.0016 18.0 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain C1_1 PF00130.17 EGO27185.1 - 0.0059 16.3 3.1 0.017 14.8 2.1 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_2 PF14445.1 EGO27185.1 - 0.1 12.5 9.3 0.021 14.7 1.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FYVE PF01363.16 EGO27185.1 - 1.6 8.6 13.1 0.098 12.5 4.7 2.2 2 0 0 2 2 2 0 FYVE zinc finger Response_reg PF00072.19 EGO27186.1 - 3.9e-24 84.8 0.0 6.9e-17 61.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DUF3546 PF12066.3 EGO27187.1 - 1.7e-16 60.2 1.1 8.4e-16 57.9 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EGO27187.1 - 5.4e-13 49.6 0.3 5.4e-13 49.6 0.2 3.8 2 1 2 4 4 4 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EGO27187.1 - 2.1e-05 24.0 2.6 2.7e-05 23.6 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 EGO27187.1 - 0.01 15.9 3.1 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGO27187.1 - 0.099 13.0 4.6 0.06 13.7 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1871 PF08958.5 EGO27187.1 - 0.26 11.3 1.0 4.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) zf-C2H2_4 PF13894.1 EGO27187.1 - 0.87 10.0 3.8 19 5.8 0.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger RRM_6 PF14259.1 EGO27188.1 - 2.6e-06 27.2 0.0 9.6e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO27188.1 - 0.015 14.8 0.0 0.95 9.1 0.0 2.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U79_P34 PF03064.11 EGO27188.1 - 0.028 13.9 4.8 0.046 13.2 3.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Prog_receptor PF02161.10 EGO27188.1 - 0.034 13.0 1.8 0.041 12.7 1.2 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF2414 PF10309.4 EGO27189.1 - 2.1e-05 24.1 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 EGO27189.1 - 0.014 15.7 2.2 0.014 15.7 1.5 3.0 3 1 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 KH_1 PF00013.24 EGO27190.1 - 9.9e-05 21.9 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EGO27190.1 - 0.0027 17.3 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EGO27190.1 - 0.0081 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 KH domain Peptidase_S10 PF00450.17 EGO27192.1 - 2.4e-107 359.6 0.1 3.7e-107 359.0 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGO27192.1 - 0.0004 20.3 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Nop PF01798.13 EGO27193.1 - 6.8e-58 194.2 0.4 1.3e-57 193.2 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGO27193.1 - 1.5e-27 95.1 0.2 2.7e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGO27193.1 - 3.3e-19 68.8 1.9 7.6e-19 67.6 0.7 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Nucleo_P87 PF07267.6 EGO27193.1 - 0.11 11.1 7.9 0.19 10.3 5.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 EGO27193.1 - 9.6 4.1 19.2 25 2.6 13.0 1.8 2 0 0 2 2 2 0 CDC45-like protein adh_short PF00106.20 EGO27194.1 - 5.7e-06 26.3 0.0 0.52 10.2 0.1 3.4 1 1 0 3 3 3 3 short chain dehydrogenase ATP_bind_3 PF01171.15 EGO27195.1 - 2.5e-18 66.2 0.0 4.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EGO27195.1 - 0.0034 17.6 0.0 0.0091 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EGO27195.1 - 0.025 13.1 0.0 0.04 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DNA_pol_B_palm PF14792.1 EGO27195.1 - 0.031 14.3 0.1 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Asn_synthase PF00733.16 EGO27195.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase HIPIP PF01355.12 EGO27195.1 - 0.91 9.6 7.3 12 6.0 0.5 3.2 3 0 0 3 3 3 0 High potential iron-sulfur protein PUF PF00806.14 EGO27196.1 - 2.4e-23 80.2 0.0 9.8e-05 21.6 0.0 8.4 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat Abhydrolase_6 PF12697.2 EGO27197.1 - 1.3e-29 103.6 0.2 2e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO27197.1 - 3.7e-14 52.7 0.0 7.5e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO27197.1 - 0.0016 18.2 0.0 0.0048 16.7 0.0 1.9 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EGO27197.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DAGK_cat PF00781.19 EGO27198.1 - 0.015 14.7 0.3 0.031 13.7 0.2 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Bystin PF05291.6 EGO27199.1 - 2.9e-95 318.6 0.0 1.2e-62 211.5 0.0 2.2 1 1 1 2 2 2 2 Bystin BUD22 PF09073.5 EGO27199.1 - 0.47 9.4 14.5 0.67 8.9 10.0 1.1 1 0 0 1 1 1 0 BUD22 Epimerase PF01370.16 EGO27200.1 - 2.6e-44 151.4 0.0 4.8e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO27200.1 - 4.8e-10 38.6 0.0 7.2e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO27200.1 - 2.4e-09 36.5 0.0 3.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGO27200.1 - 2.5e-08 33.1 0.1 0.00029 19.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EGO27200.1 - 3.5e-07 29.4 0.2 0.002 17.0 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO27200.1 - 2.6e-05 24.2 0.0 6.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO27200.1 - 0.033 14.1 0.3 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Nyv1_N PF09426.5 EGO27201.1 - 0.074 12.6 0.0 0.079 12.5 0.0 1.0 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal RGS PF00615.14 EGO27204.1 - 4.2e-40 136.5 0.3 1.2e-39 135.0 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EGO27204.1 - 2.6e-13 49.4 0.0 6.1e-06 25.8 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 EGO27204.1 - 0.0032 17.2 0.1 0.5 10.2 0.0 3.3 3 0 0 3 3 3 1 Winged helix-turn-helix Cyt-b5 PF00173.23 EGO27205.1 - 2.1e-09 37.0 1.0 3.6e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Nup160 PF11715.3 EGO27207.1 - 6.9e-37 126.8 0.0 1.1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Fungal_trans PF04082.13 EGO27208.1 - 8.8e-20 70.6 0.5 1.6e-19 69.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO27208.1 - 3.2e-05 23.7 8.7 5.4e-05 23.0 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 EGO27209.1 - 0.00073 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO27209.1 - 0.0073 15.9 0.1 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EGO27209.1 - 0.0076 15.8 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO27209.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1840 PF08895.6 EGO27209.1 - 0.027 14.4 1.6 0.035 14.1 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) XPC-binding PF09280.6 EGO27209.1 - 0.028 13.8 3.5 0.071 12.5 2.4 1.8 1 1 0 1 1 1 0 XPC-binding domain Inhibitor_I9 PF05922.11 EGO27209.1 - 0.069 13.7 0.7 0.15 12.6 0.5 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 DUF3573 PF12097.3 EGO27209.1 - 0.29 9.6 1.8 0.33 9.5 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3835 PF12927.2 EGO27209.1 - 2.8 8.9 5.7 5.4 8.0 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) TPR_11 PF13414.1 EGO27210.1 - 1.7e-16 59.6 2.6 1.8e-16 59.5 1.8 1.0 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EGO27210.1 - 1.1e-08 34.2 1.1 1.1e-08 34.2 0.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO27210.1 - 4.3e-08 32.4 0.6 4.3e-08 32.4 0.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO27210.1 - 2.2e-06 28.1 1.3 2.6e-06 27.9 0.9 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO27210.1 - 5.8e-05 23.3 1.0 8.8e-05 22.7 0.7 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO27210.1 - 0.00015 22.0 0.1 0.00025 21.4 0.0 1.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO27210.1 - 0.00047 19.7 1.5 0.004 16.8 0.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO27210.1 - 0.001 19.0 2.2 0.011 15.9 0.1 2.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO27210.1 - 0.002 17.9 0.8 0.0051 16.7 0.6 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_3 PF07720.7 EGO27210.1 - 0.0052 16.5 0.4 0.0052 16.5 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EGO27210.1 - 0.0063 16.7 0.2 0.0065 16.7 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Apc3 PF12895.2 EGO27210.1 - 0.0095 16.0 0.4 0.01 15.9 0.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGO27210.1 - 0.025 14.3 0.0 0.063 13.1 0.0 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EGO27210.1 - 0.027 14.3 0.5 0.041 13.7 0.4 1.6 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EGO27210.1 - 0.13 12.7 0.2 0.13 12.7 0.1 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat SnoaL_3 PF13474.1 EGO27210.1 - 0.15 12.0 0.1 0.16 11.9 0.1 1.0 1 0 0 1 1 1 0 SnoaL-like domain DUF4398 PF14346.1 EGO27210.1 - 0.27 11.2 2.7 0.34 10.9 1.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) Aldo_ket_red PF00248.16 EGO27211.1 - 1e-43 149.2 0.0 1.3e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family B12D PF06522.6 EGO27212.1 - 7.8e-16 57.5 0.1 1.1e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Isochorismatase PF00857.15 EGO27214.1 - 4.9e-30 104.7 0.0 6.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF1748 PF08520.5 EGO27215.1 - 7.5e-24 83.1 0.0 8.1e-24 83.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coat_F PF07875.7 EGO27215.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Coat F domain DAD PF02109.11 EGO27216.1 - 1.7e-48 163.3 1.2 2e-48 163.1 0.8 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.13 EGO27217.1 - 1e-10 41.4 0.2 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Adap_comp_sub PF00928.16 EGO27218.1 - 1.7e-49 168.2 0.0 2.1e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO27218.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hexokinase_1 PF00349.16 EGO27219.1 - 6.2e-63 211.8 0.0 3.4e-62 209.4 0.0 1.9 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGO27219.1 - 6.8e-62 208.8 0.1 4.7e-36 124.2 0.0 2.7 2 1 0 2 2 2 2 Hexokinase DUF3445 PF11927.3 EGO27222.1 - 7.2e-62 209.0 0.0 1.6e-46 158.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) bZIP_1 PF00170.16 EGO27223.1 - 2.7e-11 43.2 8.7 4.5e-11 42.5 6.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 EGO27223.1 - 1.2e-08 35.0 20.8 2.3e-08 34.1 10.9 3.6 2 1 0 2 2 2 1 Aft1 HRA domain bZIP_2 PF07716.10 EGO27223.1 - 2.6e-06 27.1 8.8 5.7e-06 26.0 6.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 EGO27223.1 - 5.1e-05 23.7 7.7 5.1e-05 23.7 5.3 3.7 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Spt5_N PF11942.3 EGO27223.1 - 0.027 15.0 10.5 0.06 13.9 7.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF3469 PF11952.3 EGO27223.1 - 0.086 12.5 0.8 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Nop53 PF07767.6 EGO27223.1 - 0.4 9.6 13.3 0.14 11.1 7.2 1.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 EGO27223.1 - 2.2 6.2 8.0 3.7 5.4 5.5 1.3 1 0 0 1 1 1 0 CDC45-like protein bZIP_Maf PF03131.12 EGO27223.1 - 5.1 7.4 12.3 0.5 10.7 5.0 2.0 2 1 0 2 2 2 0 bZIP Maf transcription factor DUF3014 PF11219.3 EGO27224.1 - 0.042 13.7 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Mt_ATP-synt_D PF05873.7 EGO27226.1 - 7e-10 38.7 1.4 8.2e-10 38.5 1.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LsmAD PF06741.8 EGO27226.1 - 0.0069 16.4 1.8 0.57 10.3 0.0 2.2 2 0 0 2 2 2 2 LsmAD domain GAS PF13851.1 EGO27226.1 - 0.013 14.6 3.6 0.017 14.3 2.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cast PF10174.4 EGO27226.1 - 0.038 12.0 1.3 0.13 10.2 0.2 1.8 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Aminotran_3 PF00202.16 EGO27226.1 - 0.087 11.6 1.1 2.2 7.0 0.0 2.5 1 1 2 3 3 3 0 Aminotransferase class-III DUF1327 PF07041.6 EGO27226.1 - 0.1 12.4 0.5 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) hGDE_central PF14702.1 EGO27226.1 - 0.17 11.0 1.2 1.2 8.2 0.8 1.7 1 1 1 2 2 2 0 central domain of human glycogen debranching enzyme DUF948 PF06103.6 EGO27226.1 - 0.39 10.6 3.1 0.91 9.4 1.7 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2838 PF10998.3 EGO27227.1 - 3.2e-38 130.0 9.2 3.2e-38 130.0 6.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) A_deamin PF02137.13 EGO27228.1 - 6.3e-70 236.1 0.0 7.6e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Pectate_lyase_3 PF12708.2 EGO27229.1 - 1.7e-77 260.5 25.1 2.3e-62 211.0 9.7 3.3 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO27229.1 - 1.9e-05 24.0 0.3 0.025 14.0 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase FAD_binding_4 PF01565.18 EGO27232.1 - 1.6e-30 105.4 3.2 1.6e-30 105.4 2.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGO27232.1 - 6.8e-07 29.0 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Mig-14 PF07395.6 EGO27232.1 - 0.0061 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Mig-14 Methyltransf_16 PF10294.4 EGO27234.1 - 3.4e-47 160.1 0.0 4.3e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO27234.1 - 0.00011 22.7 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO27234.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain BolA PF01722.13 EGO27235.1 - 1.5e-15 56.9 0.0 1.6e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Stb3 PF10330.4 EGO27235.1 - 0.045 13.4 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative Sin3 binding protein COX15-CtaA PF02628.10 EGO27236.1 - 6.7e-91 304.2 11.5 8.4e-91 303.9 8.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Proteasome PF00227.21 EGO27237.1 - 1.2e-55 187.7 0.0 1.5e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO27237.1 - 1.9e-13 49.4 1.6 4.1e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PHTB1_N PF14727.1 EGO27239.1 - 0.062 12.2 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 PTHB1 N-terminus Reo_sigmaC PF04582.7 EGO27240.1 - 0.23 10.6 3.6 0.3 10.2 2.1 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 EGO27240.1 - 0.52 9.2 20.6 0.63 9.0 14.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Tfb2 PF03849.9 EGO27240.1 - 1.6 7.2 10.0 2 6.9 7.0 1.0 1 0 0 1 1 1 0 Transcription factor Tfb2 RR_TM4-6 PF06459.7 EGO27240.1 - 1.9 8.3 16.8 2.3 8.0 11.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1929 PF09118.6 EGO27240.1 - 2.2 8.4 4.7 3.6 7.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1929) DUF883 PF05957.8 EGO27240.1 - 5.1 7.5 11.3 1.8e+02 2.6 7.8 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PP2C_C PF07830.8 EGO27240.1 - 5.6 7.1 9.6 6.9 6.8 0.1 3.0 1 1 2 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1675 PF07897.6 EGO27240.1 - 5.6 6.7 12.7 7.1 6.4 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FAM60A PF15396.1 EGO27240.1 - 7.3 6.2 12.2 10 5.7 8.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A HNH_2 PF13391.1 EGO27241.1 - 3.3e-06 26.7 0.1 8.7e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease MS_channel PF00924.13 EGO27242.1 - 2.4e-21 75.9 1.9 4.6e-21 75.0 1.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGO27242.1 - 8.5e-06 24.7 0.3 0.00022 20.2 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EGO27242.1 - 3.7e-05 23.2 0.5 0.0014 18.2 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EGO27242.1 - 0.00038 19.6 0.3 0.0019 17.4 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EGO27242.1 - 0.0025 17.8 0.3 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EGO27242.1 - 0.032 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF3628 PF12300.3 EGO27242.1 - 4.5 7.2 11.3 4.5 7.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) GTP_EFTU PF00009.22 EGO27244.1 - 7.5e-35 120.0 0.0 1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO27244.1 - 1.8e-08 34.4 0.0 7.8e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO27244.1 - 0.00028 20.9 0.4 0.00075 19.5 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO27244.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SSB PF00436.20 EGO27245.1 - 1.7e-15 56.7 0.0 2.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Tymo_45kd_70kd PF03251.8 EGO27245.1 - 0.028 13.1 0.3 0.028 13.1 0.2 1.7 2 0 0 2 2 2 0 Tymovirus 45/70Kd protein Pex2_Pex12 PF04757.9 EGO27247.1 - 7.8e-51 172.7 4.2 9.6e-51 172.4 2.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EGO27247.1 - 9e-07 28.8 1.5 1.5e-06 28.1 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO27247.1 - 6.1e-06 25.9 2.5 1e-05 25.2 1.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO27247.1 - 0.00011 21.8 1.1 0.00018 21.1 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO27247.1 - 0.015 14.9 0.7 0.026 14.1 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 EGO27247.1 - 0.04 13.6 0.2 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_4 PF15227.1 EGO27247.1 - 0.043 13.6 2.7 0.076 12.9 1.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGO27247.1 - 1.5 8.5 5.3 7.9 6.1 4.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain NPDC1 PF06809.6 EGO27249.1 - 0.072 11.8 0.0 0.079 11.7 0.0 1.0 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) GDPD PF03009.12 EGO27250.1 - 2.1e-10 40.5 0.0 5.1e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.22 EGO27251.1 - 1.2e-24 87.1 0.0 2.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO27251.1 - 2.6e-11 44.0 0.1 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGO27251.1 - 2e-05 23.9 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EGO27251.1 - 5.3e-05 21.9 0.1 0.11 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGO27251.1 - 0.00051 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EGO27251.1 - 0.0024 16.9 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EGO27251.1 - 0.0079 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EGO27251.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGO27251.1 - 0.019 14.8 0.1 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EGO27251.1 - 0.022 15.5 0.0 0.046 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO27251.1 - 0.024 14.1 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EGO27251.1 - 0.043 13.2 0.3 0.58 9.5 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 EGO27251.1 - 0.047 13.6 0.6 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 EGO27251.1 - 0.048 13.9 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO27251.1 - 0.11 12.5 0.0 5.6 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Autoind_synth PF00765.12 EGO27251.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Autoinducer synthetase AAA_18 PF13238.1 EGO27251.1 - 0.18 12.0 0.0 0.84 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGO27251.1 - 0.26 10.1 0.0 0.96 8.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_88 PF07470.8 EGO27253.1 - 1.2e-21 77.0 0.9 1.7e-21 76.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Na_Ca_ex PF01699.19 EGO27254.1 - 2.8e-08 33.4 29.2 0.00011 21.8 4.1 3.7 3 2 0 3 3 3 2 Sodium/calcium exchanger protein UPF0182 PF03699.8 EGO27254.1 - 0.07 11.0 0.9 0.11 10.3 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Acyltransferase PF01553.16 EGO27255.1 - 1.5e-16 60.0 0.0 1.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase MRC1 PF09444.5 EGO27257.1 - 3.7e-17 62.9 26.7 3.7e-17 62.9 18.5 6.4 5 1 1 6 6 6 1 MRC1-like domain p450 PF00067.17 EGO27258.1 - 3.3e-74 250.1 0.0 4.4e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 EGO27259.1 - 3.5e-23 82.6 0.0 4.2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO27259.1 - 1.3e-19 70.7 0.1 1.6e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO27259.1 - 2.6e-11 43.5 0.0 5.1e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Ribosomal_L3 PF00297.17 EGO27260.1 - 4.2e-120 400.0 7.5 5e-120 399.8 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.1 EGO27261.1 - 2.4e-10 40.1 0.5 6.4e-05 22.8 0.0 5.1 4 1 1 5 5 5 1 PPR repeat family PPR PF01535.15 EGO27261.1 - 2.8e-10 39.4 0.5 0.00028 20.6 0.0 5.8 5 1 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 EGO27261.1 - 2.9e-07 30.2 0.7 0.09 13.1 0.0 5.6 5 1 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGO27261.1 - 4.7e-07 29.1 3.1 7.4e-05 22.1 0.0 3.6 4 0 0 4 4 4 2 PPR repeat Ras PF00071.17 EGO27262.1 - 3.2e-47 159.9 0.0 3.2e-43 146.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGO27262.1 - 2.2e-20 73.3 0.0 4.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO27262.1 - 2.7e-11 43.0 0.0 4.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO27262.1 - 8.4e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGO27262.1 - 0.00015 20.9 0.1 0.00036 19.7 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGO27262.1 - 0.0018 17.4 0.0 0.0061 15.8 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGO27262.1 - 0.0023 17.4 0.1 0.056 12.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGO27262.1 - 0.004 17.2 0.0 0.0074 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO27262.1 - 0.026 14.4 0.0 0.096 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGO27262.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EGO27262.1 - 0.03 13.4 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO27262.1 - 0.048 13.4 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Septin PF00735.13 EGO27262.1 - 0.071 12.1 0.1 0.39 9.6 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 EGO27262.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S7e PF01251.13 EGO27263.1 - 1.2e-84 282.5 5.2 1.3e-84 282.4 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_11 PF13414.1 EGO27264.1 - 6.2e-20 70.6 0.7 4.8e-16 58.1 0.1 2.2 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGO27264.1 - 8.5e-11 40.9 4.1 0.011 15.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO27264.1 - 9e-09 34.6 2.7 0.027 14.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO27264.1 - 0.0038 17.8 0.5 2.5 8.8 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO27264.1 - 0.0041 17.0 0.4 2.4 8.1 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO27264.1 - 0.0061 16.6 0.5 0.011 15.8 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGO27264.1 - 0.021 14.6 0.2 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO27264.1 - 0.021 14.5 0.2 0.61 10.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO27264.1 - 0.033 14.5 0.9 3 8.2 0.0 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO27264.1 - 0.043 14.4 0.0 22 6.0 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DAO PF01266.19 EGO27265.1 - 1.1e-43 149.5 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO27265.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO27265.1 - 0.014 15.4 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO27265.1 - 0.015 14.4 0.0 0.96 8.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mqo PF06039.10 EGO27265.1 - 0.015 13.5 0.0 0.051 11.7 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GMC_oxred_N PF00732.14 EGO27265.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.7 EGO27265.1 - 0.036 12.9 0.0 0.44 9.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGO27265.1 - 0.058 13.2 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO27265.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain SH3_1 PF00018.23 EGO27266.1 - 1.2e-21 75.7 0.0 1.1e-10 40.7 0.0 3.0 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EGO27266.1 - 4.7e-18 64.5 0.7 1.4e-08 34.1 0.0 3.3 4 0 0 4 4 4 2 Variant SH3 domain SH3_2 PF07653.12 EGO27266.1 - 6.6e-18 63.9 0.0 1.9e-09 36.8 0.0 3.6 4 0 0 4 4 4 2 Variant SH3 domain PX PF00787.19 EGO27266.1 - 2e-07 30.7 0.0 4.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EGO27266.1 - 0.0082 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Ribosomal_L12 PF00542.14 EGO27267.1 - 6.8e-20 70.8 2.3 6.8e-20 70.8 1.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain CDC37_C PF08564.5 EGO27267.1 - 0.033 14.0 2.5 0.42 10.4 0.2 2.1 1 1 1 2 2 2 0 Cdc37 C terminal domain TAF8_C PF10406.4 EGO27267.1 - 1 9.4 3.8 0.41 10.7 0.3 2.1 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term p450 PF00067.17 EGO27270.1 - 4.2e-67 226.6 0.0 4.7e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 URO-D PF01208.12 EGO27273.1 - 3.8e-121 404.2 0.0 4.3e-121 404.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DSPn PF14671.1 EGO27274.1 - 1.2e-37 129.0 0.0 5.3e-36 123.6 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EGO27274.1 - 9.6e-16 57.5 0.0 1.9e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO27274.1 - 3.7e-05 23.1 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGO27274.1 - 0.0009 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGO27274.1 - 0.046 13.9 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family ANTH PF07651.11 EGO27274.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Ank_2 PF12796.2 EGO27276.1 - 5.3e-20 71.5 0.7 7.8e-10 38.9 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO27276.1 - 6.5e-20 69.8 0.2 3.1e-09 36.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGO27276.1 - 4.4e-17 61.7 0.1 5.8e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO27276.1 - 5e-16 58.7 1.9 4.1e-10 39.9 0.1 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO27276.1 - 1.2e-15 56.0 0.3 1.7e-05 24.5 0.0 4.8 5 0 0 5 5 4 2 Ankyrin repeat KilA-N PF04383.8 EGO27276.1 - 4.5e-05 23.0 0.4 0.00053 19.5 0.0 2.7 2 1 0 2 2 2 1 KilA-N domain Acyl-CoA_dh_C PF12806.2 EGO27276.1 - 0.0091 15.8 3.0 0.39 10.5 0.0 2.9 3 0 0 3 3 3 1 Acetyl-CoA dehydrogenase C-terminal like IncA PF04156.9 EGO27276.1 - 0.015 14.9 13.7 0.16 11.5 1.2 2.3 2 0 0 2 2 2 0 IncA protein FUSC PF04632.7 EGO27276.1 - 4 5.7 5.6 7.3 4.8 3.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bap31 PF05529.7 EGO27276.1 - 4.1 6.8 7.2 2 7.8 1.2 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like 4HB_MCP_1 PF12729.2 EGO27276.1 - 9.4 5.5 8.4 3.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction Nucleoside_tran PF01733.13 EGO27278.1 - 5.9e-33 114.3 11.2 1e-32 113.5 7.8 1.3 1 0 0 1 1 1 1 Nucleoside transporter Nucleoside_tran PF01733.13 EGO27279.1 - 8.1e-36 123.7 9.9 8.1e-36 123.7 6.8 1.6 2 0 0 2 2 2 1 Nucleoside transporter ADH_N PF08240.7 EGO27280.1 - 7.9e-26 89.9 3.0 2e-25 88.6 2.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO27280.1 - 1.6e-18 66.5 0.2 2.6e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO27280.1 - 0.00028 20.0 0.1 0.00049 19.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACBP PF00887.14 EGO27281.1 - 1.1e-26 92.2 0.0 1.6e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein DUF605 PF04652.11 EGO27281.1 - 0.25 10.7 7.8 0.29 10.4 5.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF1663 PF07909.6 EGO27284.1 - 0.076 11.5 0.0 0.09 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) dUTPase PF00692.14 EGO27285.1 - 1e-39 134.9 0.0 1.2e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase Sugar_tr PF00083.19 EGO27286.1 - 8.4e-73 245.4 23.3 1.4e-48 165.5 3.1 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGO27286.1 - 1.1e-18 67.0 43.2 3.9e-16 58.7 16.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO27286.1 - 0.0082 15.9 1.6 3.2 7.6 0.0 3.1 1 1 1 2 2 2 2 MFS_1 like family DUF4381 PF14316.1 EGO27286.1 - 0.14 12.2 0.0 8.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2530 PF10745.4 EGO27286.1 - 0.18 11.8 5.2 0.23 11.4 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) DUF697 PF05128.7 EGO27286.1 - 0.19 11.2 1.4 0.26 10.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF697) adh_short PF00106.20 EGO27287.1 - 2.4e-23 82.8 2.3 3.2e-23 82.4 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO27287.1 - 2.9e-20 73.0 0.0 3.6e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO27287.1 - 9.5e-06 25.3 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGO27287.1 - 0.0048 16.5 0.8 0.0071 16.0 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EGO27287.1 - 0.047 13.4 0.4 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_31 PF13847.1 EGO27287.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF962 PF06127.6 EGO27288.1 - 7.2e-22 77.0 1.9 2.6e-21 75.3 1.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) RVP_2 PF08284.6 EGO27290.1 - 0.044 13.7 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Imm_superinfect PF14373.1 EGO27290.1 - 0.073 12.7 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Superinfection immunity protein DiS_P_DiS PF06750.8 EGO27291.1 - 0.077 12.7 2.2 0.12 12.1 1.5 1.3 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF4011 PF13195.1 EGO27291.1 - 1.9 8.4 7.6 0.29 11.1 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Vfa1 PF08432.5 EGO27291.1 - 2.9 7.9 10.6 0.34 10.8 4.5 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MTP18 PF10558.4 EGO27292.1 - 1.5e-57 193.6 0.7 1.9e-57 193.3 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) IF-2B PF01008.12 EGO27293.1 - 3.4e-86 288.7 0.2 4.1e-86 288.4 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family XRN_N PF03159.13 EGO27294.1 - 3e-108 360.6 0.0 3.5e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EGO27294.1 - 3.9e-05 23.3 2.1 6.3e-05 22.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO27294.1 - 0.065 12.9 1.2 0.11 12.2 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EGO27294.1 - 0.27 11.1 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G p450 PF00067.17 EGO27295.1 - 3.7e-60 203.7 0.0 4.1e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Roughex PF06020.6 EGO27296.1 - 0.063 11.9 0.1 0.063 11.9 0.0 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Longin PF13774.1 EGO27297.1 - 9.4e-29 98.8 0.1 1.4e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGO27297.1 - 5.1e-17 61.2 0.2 8.4e-17 60.5 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EGO27297.1 - 0.056 13.2 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF651 PF04895.7 EGO27297.1 - 0.21 11.2 1.3 12 5.6 0.0 2.7 2 1 1 3 3 3 0 Archaeal protein of unknown function (DUF651) DUF4381 PF14316.1 EGO27299.1 - 0.051 13.6 0.2 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Retrotrans_gag PF03732.12 EGO27300.1 - 3.1e-08 33.5 0.7 3.5e-08 33.3 0.5 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein Nitrate_red_del PF02613.10 EGO27300.1 - 0.018 14.8 0.3 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 Nitrate reductase delta subunit Ca_chan_IQ PF08763.6 EGO27300.1 - 0.49 9.6 2.7 0.45 9.8 0.2 2.0 1 1 1 2 2 2 0 Voltage gated calcium channel IQ domain RVP_2 PF08284.6 EGO27301.1 - 2.6e-05 24.1 0.0 2.9e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO27301.1 - 5.2e-05 23.6 0.0 6.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO27301.1 - 6.6e-05 22.6 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease GSP_synth PF03738.9 EGO27302.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp IPK PF03770.11 EGO27303.1 - 4.1e-50 170.1 0.0 7.5e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase ECH_C PF13766.1 EGO27303.1 - 0.056 13.6 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region UCR_UQCRX_QCR9 PF05365.7 EGO27304.1 - 2.7e-18 65.3 5.2 3.8e-18 64.8 3.6 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2157 PF09925.4 EGO27304.1 - 0.12 11.9 0.3 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Flavokinase PF01687.12 EGO27305.1 - 7.3e-37 126.0 0.0 8.8e-37 125.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Myb_DNA-binding PF00249.26 EGO27306.1 - 1.9e-34 117.4 2.5 2.2e-10 40.4 0.0 5.1 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO27306.1 - 9.3e-34 115.3 1.6 4.4e-15 55.5 0.0 5.4 2 2 3 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO27306.1 - 4e-05 23.6 10.7 0.091 12.9 0.4 5.7 4 3 0 4 4 4 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EGO27306.1 - 0.012 15.5 2.9 1 9.2 0.0 3.2 1 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MamL-1 PF09596.5 EGO27306.1 - 1.2 9.0 4.2 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 MamL-1 domain DUF788 PF05620.6 EGO27307.1 - 1.8e-42 145.0 0.0 2.1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) FmdE PF02663.9 EGO27307.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon EssA PF10661.4 EGO27308.1 - 1.1 8.9 5.1 1.6 8.3 3.5 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA CAF-1_p150 PF11600.3 EGO27308.1 - 7.6 5.8 21.0 10 5.4 14.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3987 PF13148.1 EGO27308.1 - 8.6 4.8 11.0 13 4.2 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) adh_short PF00106.20 EGO27311.1 - 1.9e-05 24.6 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO27311.1 - 0.089 12.4 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 KR domain MT-A70 PF05063.9 EGO27312.1 - 3.9e-56 189.3 0.1 5.6e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Abhydrolase_6 PF12697.2 EGO27313.1 - 1.6e-32 113.2 1.2 6.6e-32 111.2 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO27313.1 - 1.1e-17 64.3 0.0 3.3e-13 49.7 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO27313.1 - 5.5e-16 58.6 0.1 8.1e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGO27313.1 - 1e-05 25.0 0.1 3.8e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Putative esterase DUF2305 PF10230.4 EGO27313.1 - 0.00072 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EGO27313.1 - 0.0009 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EGO27313.1 - 0.00099 18.7 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EGO27313.1 - 0.0023 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 EGO27313.1 - 0.003 16.0 0.0 0.0072 14.8 0.0 1.5 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.6 EGO27313.1 - 0.0047 16.6 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EGO27313.1 - 0.0063 15.7 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family UPF0227 PF05728.7 EGO27313.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 EGO27313.1 - 0.088 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Strep_his_triad PF04270.8 EGO27313.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.9 1 0 0 1 1 1 0 Streptococcal histidine triad protein Aminotran_1_2 PF00155.16 EGO27314.1 - 2.7e-75 253.5 0.0 3.7e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGO27314.1 - 3.9e-05 22.5 0.0 7.9e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO27314.1 - 0.0002 19.8 0.0 0.00033 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme YqeY PF09424.5 EGO27314.1 - 0.13 12.1 0.4 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Yqey-like protein Arf PF00025.16 EGO27315.1 - 5e-71 237.5 0.0 5.8e-71 237.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO27315.1 - 1.4e-14 53.7 0.0 1.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGO27315.1 - 6.6e-13 48.0 0.2 1.6e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO27315.1 - 3.1e-10 39.6 0.0 3.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EGO27315.1 - 6.4e-10 38.6 0.0 7.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO27315.1 - 3.3e-07 30.8 0.0 4.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO27315.1 - 0.00013 21.9 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.27 EGO27316.1 - 1.7e-28 97.3 17.2 1.3e-08 34.3 0.9 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat DKNYY PF13644.1 EGO27317.1 - 0.071 13.3 1.6 0.071 13.3 1.1 1.1 1 0 0 1 1 1 0 DKNYY family RVP_2 PF08284.6 EGO27318.1 - 1.1e-06 28.6 0.0 1.2e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO27318.1 - 3.6e-05 23.5 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO27318.1 - 0.00016 22.1 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.1 EGO27321.1 - 0.03 13.9 2.0 0.093 12.4 1.4 1.9 1 0 0 1 1 1 0 Zinc knuckle Gcd10p PF04189.8 EGO27322.1 - 6.9e-59 199.4 0.0 1.3e-57 195.2 0.0 2.4 1 1 0 1 1 1 1 Gcd10p family Iso_dh PF00180.15 EGO27323.1 - 2.6e-98 329.1 0.0 3.2e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Atg14 PF10186.4 EGO27326.1 - 0.00027 19.9 0.9 0.00033 19.7 0.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGO27326.1 - 0.0006 19.4 1.6 0.00082 19.0 1.1 1.3 1 0 0 1 1 1 1 IncA protein AIP3 PF03915.8 EGO27326.1 - 0.003 16.5 0.5 0.004 16.1 0.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF745 PF05335.8 EGO27326.1 - 0.039 13.4 1.2 0.062 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MerR-DNA-bind PF09278.6 EGO27326.1 - 0.044 14.1 11.2 18 5.8 0.3 3.4 2 1 1 3 3 3 0 MerR, DNA binding DUF1204 PF06721.6 EGO27326.1 - 0.2 10.8 3.5 0.26 10.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) B-block_TFIIIC PF04182.7 EGO27327.1 - 7.9e-11 41.6 0.2 5e-08 32.6 0.0 3.3 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EGO27327.1 - 0.00017 20.8 0.0 0.01 15.1 0.0 3.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 EGO27327.1 - 0.00066 19.9 0.1 0.026 14.8 0.0 3.6 5 0 0 5 5 5 1 Winged helix DNA-binding domain MarR_2 PF12802.2 EGO27327.1 - 0.00078 19.0 0.3 0.082 12.5 0.0 3.4 3 0 0 3 3 3 1 MarR family Helicase_C PF00271.26 EGO27329.1 - 1.2e-07 31.4 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3381 PF11861.3 EGO27332.1 - 0.049 13.1 1.9 0.075 12.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) zf-CCHC_3 PF13917.1 EGO27333.1 - 1.3e-06 28.0 1.4 2.5e-06 27.1 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO27333.1 - 4.2e-05 23.2 5.5 6.8e-05 22.6 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO27333.1 - 0.25 10.8 3.6 0.44 10.0 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Alpha_kinase PF02816.13 EGO27334.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family DUF763 PF05559.6 EGO27334.1 - 0.088 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF724 PF05266.9 EGO27335.1 - 0.023 14.3 5.7 0.041 13.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tweety PF04906.8 EGO27335.1 - 0.045 12.1 0.3 0.068 11.5 0.2 1.2 1 0 0 1 1 1 0 Tweety Spc24 PF08286.6 EGO27335.1 - 0.084 12.5 4.1 0.15 11.7 2.9 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DIRP PF06584.8 EGO27335.1 - 0.5 10.2 3.8 2 8.3 2.1 2.2 1 1 1 2 2 2 0 DIRP ATG16 PF08614.6 EGO27335.1 - 4.1 7.1 15.6 0.2 11.4 6.6 1.9 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Amidohydro_4 PF13147.1 EGO27336.1 - 1.1e-08 35.5 0.2 1.6e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EGO27336.1 - 1.5e-07 31.2 0.1 3.4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Kinesin PF00225.18 EGO27337.1 - 1.1e-106 356.3 0.0 1.2e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain PRAI PF00697.17 EGO27337.1 - 0.059 12.9 0.3 0.089 12.3 0.2 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase EMP24_GP25L PF01105.19 EGO27338.1 - 2.1e-49 167.6 0.4 2.5e-49 167.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.13 EGO27339.1 - 8.5e-50 167.8 0.5 8.5e-50 167.8 0.3 1.5 2 0 0 2 2 2 1 RanBP1 domain DUF1681 PF07933.9 EGO27339.1 - 2.1e-06 27.4 1.8 2.7e-06 27.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 EGO27339.1 - 0.00022 20.9 0.4 0.0012 18.4 0.3 1.9 1 1 0 1 1 1 1 WH1 domain Usp PF00582.21 EGO27339.1 - 0.047 13.8 1.4 0.1 12.7 1.0 1.6 1 0 0 1 1 1 0 Universal stress protein family AAA_2 PF07724.9 EGO27340.1 - 6.5e-37 127.0 0.0 1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGO27340.1 - 2.6e-14 53.5 0.0 4.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGO27340.1 - 9.4e-11 41.4 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGO27340.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO27340.1 - 0.00011 21.4 0.0 0.0029 16.7 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EGO27340.1 - 0.00013 22.7 0.0 0.00028 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO27340.1 - 0.00014 21.9 0.0 0.0019 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO27340.1 - 0.00046 20.2 0.0 0.00092 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EGO27340.1 - 0.0021 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 EGO27340.1 - 0.0031 16.9 0.0 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EGO27340.1 - 0.0039 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO27340.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EGO27340.1 - 0.01 15.2 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 EGO27340.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase RuvB_N PF05496.7 EGO27340.1 - 0.015 14.3 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EGO27340.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EGO27340.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EGO27340.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 EGO27340.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EGO27340.1 - 0.026 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EGO27340.1 - 0.029 14.6 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO27340.1 - 0.043 13.4 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EGO27340.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EGO27340.1 - 0.077 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EGO27340.1 - 0.081 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EGO27340.1 - 0.1 12.1 0.0 0.87 9.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGO27340.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EGO27340.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 EGO27340.1 - 0.25 10.0 0.0 0.88 8.2 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus Cactin_mid PF10312.4 EGO27341.1 - 3.4e-63 212.3 4.7 1.1e-62 210.7 3.3 1.9 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EGO27341.1 - 7.1e-58 193.6 6.2 1.4e-57 192.6 4.3 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cyclin PF08613.6 EGO27342.1 - 1.6e-05 25.3 0.1 3.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin ThiF PF00899.16 EGO27343.1 - 6.1e-49 165.3 0.0 7e-28 97.1 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EGO27343.1 - 4.3e-45 152.9 0.2 1.2e-44 151.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EGO27343.1 - 9.9e-39 130.7 5.1 5.6e-28 96.3 0.3 3.5 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGO27343.1 - 5.1e-22 76.9 2.1 4.9e-18 64.2 0.7 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Glyco_hydro_92 PF07971.7 EGO27344.1 - 9.6e-145 483.0 4.8 1.3e-144 482.6 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Biotin_lipoyl_2 PF13533.1 EGO27344.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like Cyclin PF08613.6 EGO27345.1 - 0.00047 20.6 0.0 0.00071 20.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.3 EGO27347.1 - 2.6e-117 392.3 0.0 3.6e-117 391.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EGO27347.1 - 4.4e-21 74.9 0.0 9.4e-20 70.6 0.0 2.4 2 1 1 3 3 3 1 N1221-like protein CBM_X2 PF03442.9 EGO27350.1 - 0.00025 20.7 0.0 0.0003 20.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate binding domain X2 APC_15aa PF05972.6 EGO27350.1 - 0.1 12.6 0.4 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 APC 15 residue motif Diphthamide_syn PF01866.12 EGO27351.1 - 1.9e-88 296.6 0.1 6.3e-33 114.3 0.3 4.1 3 1 0 3 3 3 3 Putative diphthamide synthesis protein Patched PF02460.13 EGO27352.1 - 6.3e-69 232.7 13.1 5.2e-39 133.8 0.1 3.2 2 1 1 3 3 3 3 Patched family Sterol-sensing PF12349.3 EGO27352.1 - 2.8e-46 156.7 18.0 3.9e-25 88.1 0.2 3.9 4 0 0 4 4 4 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EGO27352.1 - 1.4e-08 32.6 3.8 2.9e-08 31.6 2.6 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family RRM_1 PF00076.17 EGO27353.1 - 3.3e-13 49.0 0.0 4.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27353.1 - 5.8e-08 32.4 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27353.1 - 6.5e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ThiS-like PF14453.1 EGO27353.1 - 0.055 13.3 0.3 0.09 12.6 0.2 1.3 1 0 0 1 1 1 0 ThiS-like ubiquitin zf-H2C2_2 PF13465.1 EGO27354.1 - 6.3e-07 29.3 11.4 0.0025 17.9 1.2 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGO27354.1 - 0.00072 19.7 0.8 0.00072 19.7 0.5 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO27354.1 - 0.00075 19.6 17.6 0.03 14.6 1.9 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EGO27354.1 - 0.58 10.4 6.0 14 6.0 0.6 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FAD_binding_6 PF00970.19 EGO27355.1 - 5.5e-11 42.4 0.0 1.2e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO27355.1 - 2.8e-09 37.5 0.0 1.5e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGO27355.1 - 0.00044 20.1 0.0 0.013 15.4 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGO27355.1 - 0.0033 17.3 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Med18 PF09637.5 EGO27357.1 - 4.9e-07 29.5 0.0 0.00034 20.2 0.0 2.1 1 1 1 2 2 2 2 Med18 protein CIAPIN1 PF05093.8 EGO27358.1 - 1.2e-29 102.3 5.1 2e-29 101.5 3.5 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Fork_head PF00250.13 EGO27359.1 - 4.8e-30 103.4 0.1 8.2e-30 102.7 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Pkinase PF00069.20 EGO27362.1 - 2.9e-69 233.1 0.0 3.7e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27362.1 - 7.4e-30 103.8 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGO27362.1 - 2.7e-16 59.8 0.2 1.2e-15 57.7 0.1 2.2 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO27362.1 - 2.7e-09 36.4 0.0 3.8e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like C2 PF00168.25 EGO27362.1 - 3.6e-06 26.7 0.2 0.0071 16.1 0.1 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 EGO27362.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO27362.1 - 0.03 13.4 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.7 EGO27363.1 - 2.6e-34 119.2 0.1 4.4e-34 118.5 0.0 1.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like MRP-S26 PF14943.1 EGO27364.1 - 0.031 13.8 1.7 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Retrotrans_gag PF03732.12 EGO27365.1 - 3.6e-06 26.9 0.2 3.6e-06 26.9 0.1 2.6 1 1 1 2 2 2 1 Retrotransposon gag protein BMFP PF04380.8 EGO27365.1 - 0.11 12.6 0.9 1.6 8.8 0.2 3.0 3 0 0 3 3 3 0 Membrane fusogenic activity zf-ribbon_3 PF13248.1 EGO27366.1 - 0.027 13.6 10.4 0.89 8.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGO27366.1 - 0.087 12.6 8.5 0.24 11.2 5.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C4pol PF14260.1 EGO27366.1 - 0.16 12.0 3.4 0.23 11.4 1.1 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Zn_Tnp_IS91 PF14319.1 EGO27366.1 - 2.5 7.6 7.5 3.9 7.0 4.5 1.8 1 1 1 2 2 2 0 Transposase zinc-binding domain Acyl-CoA_dh_1 PF00441.19 EGO27367.1 - 1.9e-29 102.7 0.4 2.9e-29 102.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO27367.1 - 1.7e-13 49.8 0.0 4.1e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO27367.1 - 2.2e-12 47.3 0.1 4.5e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO27367.1 - 9.1e-10 39.1 0.0 1.9e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Fungal_trans PF04082.13 EGO27368.1 - 5e-36 123.9 0.0 8.5e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO27368.1 - 3.3e-07 30.0 15.2 6.2e-07 29.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NB PF04159.8 EGO27368.1 - 1.1 9.0 2.6 3.3 7.5 1.8 1.8 1 0 0 1 1 1 0 NB glycoprotein Ribosomal_L19 PF01245.15 EGO27369.1 - 1.3e-17 63.6 0.0 2.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.17 EGO27369.1 - 2.6e-17 62.1 0.0 9.5e-17 60.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27369.1 - 9.8e-14 51.0 0.0 1.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27369.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMD PF08397.6 EGO27370.1 - 1.2e-05 24.7 4.1 1.8e-05 24.1 2.9 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR PF03114.13 EGO27370.1 - 0.0018 17.8 3.4 0.0058 16.1 2.1 1.7 1 1 1 2 2 2 1 BAR domain ARD PF03079.9 EGO27370.1 - 0.0024 17.8 1.8 0.0039 17.1 1.3 1.3 1 0 0 1 1 1 1 ARD/ARD' family DUF3829 PF12889.2 EGO27370.1 - 0.12 11.5 6.6 0.014 14.5 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF479 PF04336.7 EGO27370.1 - 1.2 9.2 6.1 7.8 6.6 3.1 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF479 tRNA-synt_2 PF00152.15 EGO27371.1 - 7e-100 334.0 0.0 7.1e-99 330.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO27371.1 - 3.6e-07 29.9 0.0 7.7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EGO27371.1 - 0.04 13.4 0.0 0.91 9.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) ACPS PF01648.15 EGO27373.1 - 1.3e-10 41.0 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.19 EGO27374.1 - 2.7e-13 49.7 0.0 4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGO27374.1 - 0.019 14.1 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase CBFD_NFYB_HMF PF00808.18 EGO27375.1 - 0.00078 19.4 0.0 0.00089 19.2 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LSM PF01423.17 EGO27376.1 - 3e-20 71.5 0.0 3.4e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO27376.1 - 0.0025 17.6 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Actin PF00022.14 EGO27381.1 - 2.5e-113 378.4 0.0 2.8e-113 378.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGO27381.1 - 2.4e-05 23.0 0.0 0.097 11.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Sedlin_N PF04628.8 EGO27383.1 - 4.8e-40 136.4 0.0 6.1e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGO27383.1 - 4e-08 33.0 0.0 6.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Rhomboid PF01694.17 EGO27384.1 - 1.8e-22 79.9 10.0 1.8e-22 79.9 6.9 1.8 2 0 0 2 2 2 1 Rhomboid family EBP PF05241.7 EGO27384.1 - 0.029 13.3 0.0 0.058 12.3 0.0 1.5 1 0 0 1 1 1 0 Emopamil binding protein Adeno_100 PF02438.11 EGO27384.1 - 0.12 10.5 0.2 0.23 9.6 0.0 1.5 2 0 0 2 2 2 0 Late 100kD protein DUF457 PF04307.9 EGO27384.1 - 0.56 9.5 8.8 0.055 12.8 1.9 2.2 2 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) SurE PF01975.12 EGO27385.1 - 4.6e-05 22.8 0.0 5.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_16 PF00722.16 EGO27386.1 - 6.4e-08 32.0 0.1 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Rdx PF10262.4 EGO27387.1 - 7.5e-24 83.5 0.0 9.4e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family AAA PF00004.24 EGO27388.1 - 7.2e-32 110.3 0.0 1.1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO27388.1 - 3.7e-08 33.5 0.0 2e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO27388.1 - 9.5e-07 29.6 0.0 2.6e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO27388.1 - 1.7e-06 28.1 0.1 4.6e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGO27388.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGO27388.1 - 2.4e-05 24.3 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EGO27388.1 - 2.8e-05 24.4 0.0 5.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO27388.1 - 3.3e-05 23.7 0.0 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO27388.1 - 4.9e-05 22.9 0.0 0.00052 19.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EGO27388.1 - 0.00011 21.6 0.2 0.068 12.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGO27388.1 - 0.00015 21.5 0.1 0.014 15.1 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_11 PF13086.1 EGO27388.1 - 0.00022 20.8 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGO27388.1 - 0.00049 19.1 0.1 0.01 14.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EGO27388.1 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EGO27388.1 - 0.0013 18.4 0.1 0.0045 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EGO27388.1 - 0.0026 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGO27388.1 - 0.0028 17.2 0.0 0.0062 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO27388.1 - 0.0031 16.6 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EGO27388.1 - 0.0032 17.6 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EGO27388.1 - 0.0037 16.9 0.1 0.0084 15.7 0.1 1.8 1 1 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.13 EGO27388.1 - 0.004 16.6 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EGO27388.1 - 0.0041 16.5 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.9 EGO27388.1 - 0.0047 15.9 0.0 1.8 7.4 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain TIP49 PF06068.8 EGO27388.1 - 0.0066 15.2 0.0 0.009 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_30 PF13604.1 EGO27388.1 - 0.0078 15.8 0.0 0.029 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGO27388.1 - 0.025 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EGO27388.1 - 0.027 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EGO27388.1 - 0.04 13.0 0.0 0.099 11.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGO27388.1 - 0.041 13.0 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EGO27388.1 - 0.045 12.7 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EGO27388.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EGO27388.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGO27388.1 - 0.093 13.0 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGO27388.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.7 EGO27388.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_13 PF13166.1 EGO27388.1 - 0.18 10.2 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGO27388.1 - 0.18 10.8 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 KaiC PPR_2 PF13041.1 EGO27389.1 - 4.1e-05 23.4 0.0 0.27 11.2 0.0 2.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EGO27389.1 - 0.011 15.9 0.1 33 5.0 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPMT PF05724.6 EGO27390.1 - 1.2e-23 83.6 0.0 1.6e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 EGO27390.1 - 4.6e-06 27.0 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO27390.1 - 7.4e-06 26.5 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO27390.1 - 8.8e-06 26.1 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO27390.1 - 0.0025 17.3 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO27390.1 - 0.005 17.1 0.0 0.0075 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO27390.1 - 0.063 13.0 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EGO27391.1 - 1.7e-34 119.2 0.0 2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EGO27391.1 - 2.9e-06 27.8 0.0 4.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO27391.1 - 1.6e-05 24.5 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO27391.1 - 1.9e-05 25.0 0.0 2.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO27391.1 - 0.00013 22.0 0.0 0.00025 21.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO27391.1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO27391.1 - 0.0041 17.5 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain LSM PF01423.17 EGO27392.1 - 5.5e-17 61.0 0.0 6.2e-17 60.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain DUF3722 PF12519.3 EGO27394.1 - 1.2e-97 326.2 0.0 1.6e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EGO27394.1 - 0.038 13.3 0.0 24 4.1 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic porin Pkinase PF00069.20 EGO27395.1 - 3.7e-29 101.6 0.0 1.5e-28 99.6 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27395.1 - 1.6e-26 92.9 0.0 4.4e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Gag_p17 PF00540.13 EGO27395.1 - 0.11 12.3 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) p450 PF00067.17 EGO27396.1 - 3.3e-71 240.1 0.0 3.8e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KCl_Cotrans_1 PF03522.10 EGO27398.1 - 0.0059 16.0 0.2 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 K-Cl Co-transporter type 1 (KCC1) DnaJ PF00226.26 EGO27399.1 - 4.3e-19 68.0 2.0 7.2e-19 67.2 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EGO27399.1 - 0.0013 18.8 0.8 0.0021 18.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) nlz1 PF12402.3 EGO27399.1 - 0.11 12.8 2.7 0.34 11.2 0.2 2.4 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 DUF2514 PF10721.4 EGO27399.1 - 1.9 8.1 5.0 7.5 6.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) NUFIP1 PF10453.4 EGO27401.1 - 0.016 14.6 0.7 0.033 13.6 0.5 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF3425 PF11905.3 EGO27402.1 - 7.6e-18 64.7 2.6 2.3e-15 56.6 0.9 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EGO27402.1 - 9.6e-09 35.0 8.4 2.5e-08 33.7 4.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGO27402.1 - 0.012 15.4 11.6 0.012 15.3 4.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF1237 PF06824.6 EGO27403.1 - 8.5e-144 479.2 1.2 1e-143 479.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Aconitase PF00330.15 EGO27405.1 - 3.1e-177 589.7 0.0 3.6e-177 589.5 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO27405.1 - 2.1e-42 144.3 0.0 3.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.12 EGO27406.1 - 9.7e-18 63.7 13.8 9.7e-18 63.7 9.6 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family Tau95 PF09734.4 EGO27407.1 - 1.8e-61 208.1 0.0 2.4e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF1470 PF07336.6 EGO27408.1 - 0.079 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) DUF294 PF03445.8 EGO27408.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Sld5 PF05916.6 EGO27409.1 - 3.2e-06 27.3 0.0 4.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein PapC_C PF13953.1 EGO27409.1 - 0.015 14.9 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 PapC C-terminal domain DNA_RNApol_7kD PF03604.8 EGO27410.1 - 6.3e-18 63.9 8.3 7.9e-18 63.6 5.8 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EGO27410.1 - 0.0013 18.4 0.3 0.0013 18.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGO27410.1 - 0.002 17.9 1.0 0.0027 17.4 0.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ISL3 PF14690.1 EGO27410.1 - 0.0031 17.4 2.3 0.013 15.5 0.4 2.0 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2296 PF10058.4 EGO27410.1 - 0.0077 15.9 0.4 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) OrfB_Zn_ribbon PF07282.6 EGO27410.1 - 0.01 15.5 1.5 0.014 15.0 1.1 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C3HC PF07967.8 EGO27410.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.0 1 0 0 1 1 1 0 C3HC zinc finger-like zf-ribbon_3 PF13248.1 EGO27410.1 - 0.012 14.7 0.4 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGO27410.1 - 0.022 14.6 3.4 0.053 13.4 2.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 EGO27410.1 - 0.023 14.9 4.0 0.27 11.5 0.6 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-trcl PF13451.1 EGO27410.1 - 0.036 13.7 6.5 0.69 9.5 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain zinc_ribbon_2 PF13240.1 EGO27410.1 - 0.036 13.5 1.4 0.1 12.1 1.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain NinF PF05810.7 EGO27410.1 - 0.047 13.4 0.4 0.067 13.0 0.3 1.2 1 0 0 1 1 1 0 NinF protein TF_Zn_Ribbon PF08271.7 EGO27410.1 - 0.067 12.5 3.2 0.51 9.7 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.1 EGO27410.1 - 0.07 12.8 0.4 5.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal TFIIS_C PF01096.13 EGO27410.1 - 0.1 12.2 2.0 3.1 7.4 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 EGO27410.1 - 0.1 12.1 2.9 0.97 9.0 2.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain GFA PF04828.9 EGO27410.1 - 0.12 12.2 1.3 2.3 8.2 0.9 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-Sec23_Sec24 PF04810.10 EGO27410.1 - 0.19 11.2 2.8 3.6 7.2 1.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zinc_ribbon_4 PF13717.1 EGO27410.1 - 0.25 11.0 3.6 3.7 7.3 2.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 EGO27410.1 - 0.25 10.4 4.7 3.3 6.8 0.0 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com Zn_Tnp_IS1595 PF12760.2 EGO27410.1 - 0.29 10.9 4.0 0.77 9.6 2.8 1.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L44 PF00935.14 EGO27410.1 - 0.3 11.1 4.6 3.1 7.8 1.7 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 zf-NADH-PPase PF09297.6 EGO27410.1 - 0.33 10.5 3.2 1.2 8.7 2.2 1.8 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Cas_CXXC_CXXC PF09706.5 EGO27410.1 - 0.33 11.1 4.7 6.5 7.0 0.5 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) A2L_zn_ribbon PF08792.5 EGO27410.1 - 0.73 9.3 3.6 4.5 6.8 0.2 2.0 1 1 0 2 2 2 0 A2L zinc ribbon domain RRN7 PF11781.3 EGO27410.1 - 0.82 9.2 3.8 8.6 5.9 0.6 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2197 PF09963.4 EGO27410.1 - 1 9.3 4.9 2.4 8.1 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) UPF0547 PF10571.4 EGO27410.1 - 1.4 8.6 4.6 2.2 8.0 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-dskA_traR PF01258.12 EGO27410.1 - 2.6 7.8 6.3 9.3 6.0 0.2 2.7 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger DUF35_N PF12172.3 EGO27410.1 - 8.5 6.4 7.0 3.4 7.7 0.1 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_L11 PF00298.14 EGO27413.1 - 1.7e-28 98.5 0.2 2.6e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EGO27413.1 - 2.8e-26 90.7 0.1 3.9e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Inh PF02974.9 EGO27414.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protease inhibitor Inh Glyco_hydro_cc PF11790.3 EGO27416.1 - 1.3e-48 165.5 5.6 1.4e-48 165.3 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.17 EGO27417.1 - 1.6e-26 91.6 0.0 6e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27417.1 - 1e-20 73.4 0.0 4e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 EGO27417.1 - 2.5e-19 68.6 0.9 5.2e-19 67.5 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_5 PF13893.1 EGO27417.1 - 1.9e-07 30.8 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EGO27417.1 - 9.1e-06 25.3 1.0 2.6e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 G-patch domain ACT PF01842.20 EGO27417.1 - 0.028 13.9 0.0 0.1 12.0 0.0 2.0 1 0 0 1 1 1 0 ACT domain Limkain-b1 PF11608.3 EGO27417.1 - 0.056 13.2 1.4 1.3 8.7 0.2 3.0 3 0 0 3 3 3 0 Limkain b1 Totivirus_coat PF05518.6 EGO27417.1 - 2.3 5.9 15.3 0.059 11.1 4.5 2.0 2 0 0 2 2 2 0 Totivirus coat protein Myb_DNA-bind_4 PF13837.1 EGO27419.1 - 1.4e-06 28.3 0.0 3.1e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO27419.1 - 0.0012 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EGO27419.1 - 0.0018 18.8 0.0 0.0033 18.0 0.0 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Aminotran_1_2 PF00155.16 EGO27421.1 - 6.6e-63 212.8 0.0 7.7e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGO27421.1 - 3.4e-06 26.3 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGO27421.1 - 5.7e-06 24.8 0.0 9e-06 24.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGO27421.1 - 0.00017 20.8 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGO27421.1 - 0.013 14.2 0.0 0.099 11.3 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V Thiolase_N PF00108.18 EGO27422.1 - 1.1e-87 293.3 1.9 1.5e-87 292.9 1.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO27422.1 - 1.9e-38 130.6 0.4 1.9e-38 130.6 0.3 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGO27422.1 - 0.00012 21.6 3.1 0.013 14.9 2.3 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGO27422.1 - 0.028 14.0 0.2 0.96 9.1 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2192 PF09958.4 EGO27422.1 - 0.04 13.1 0.3 0.1 11.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) COX7C PF02935.11 EGO27423.1 - 9.8e-05 22.0 1.9 9.8e-05 22.0 1.3 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Ribonuclease_3 PF00636.21 EGO27424.1 - 9.6e-47 158.1 0.0 2.7e-22 79.3 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGO27424.1 - 3.7e-28 98.0 0.0 3e-11 43.3 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.9 EGO27424.1 - 1.4e-09 37.6 0.0 4.3e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.17 EGO27424.1 - 0.00025 20.3 0.0 0.00057 19.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Chromo PF00385.19 EGO27425.1 - 8.7e-13 47.7 0.0 2.7e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain UBX PF00789.15 EGO27425.1 - 0.033 14.2 0.1 1.8 8.6 0.0 3.0 2 1 1 3 3 3 0 UBX domain ubiquitin PF00240.18 EGO27427.1 - 0.00046 19.5 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EGO27427.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Pkinase PF00069.20 EGO27428.1 - 1.2e-67 227.8 0.0 1.9e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27428.1 - 2.8e-31 108.5 0.0 5.7e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO27428.1 - 0.0019 17.1 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Bot1p PF12298.3 EGO27428.1 - 0.23 11.3 5.3 0.41 10.5 3.6 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein APH PF01636.18 EGO27428.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family MMR1 PF08505.5 EGO27428.1 - 0.38 10.7 6.3 0.56 10.1 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SDA1 PF05285.7 EGO27428.1 - 3.4 6.8 6.1 5 6.3 4.3 1.1 1 0 0 1 1 1 0 SDA1 cNMP_binding PF00027.24 EGO27429.1 - 1.2e-35 121.1 0.0 2.4e-18 65.7 0.0 2.6 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EGO27429.1 - 8.8e-12 44.2 0.1 1.9e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MFS_1 PF07690.11 EGO27431.1 - 9.7e-38 129.7 14.0 1.3e-36 126.0 11.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2109 PF09882.4 EGO27431.1 - 0.036 14.0 1.4 0.21 11.5 1.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Ytp1 PF10355.4 EGO27432.1 - 8.1e-83 277.7 3.0 1.5e-82 276.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGO27432.1 - 1.5e-15 56.6 5.1 1.5e-15 56.6 3.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) UbiA PF01040.13 EGO27433.1 - 3.2e-33 115.0 20.8 4.3e-33 114.6 14.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Rho_GDI PF02115.12 EGO27434.1 - 1.4e-50 171.4 0.0 1.6e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.10 EGO27434.1 - 0.094 12.7 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain zf-CCCH PF00642.19 EGO27435.1 - 0.00019 21.0 19.5 0.0053 16.4 2.1 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Abhydrolase_6 PF12697.2 EGO27436.1 - 1.3e-15 57.9 0.2 1.8e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO27436.1 - 1.2e-07 31.5 0.0 4.9e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO27436.1 - 3.6e-05 23.4 0.0 0.00034 20.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EGO27436.1 - 0.00025 20.5 0.0 0.0007 19.1 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) GFO_IDH_MocA PF01408.17 EGO27437.1 - 5.1e-20 72.1 0.2 9.5e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO27437.1 - 6.6e-07 29.1 0.1 3.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DUF448 PF04296.8 EGO27438.1 - 0.024 14.2 0.3 0.22 11.1 0.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF448) Proteasome PF00227.21 EGO27439.1 - 2.7e-44 150.7 0.0 3.1e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 EGO27440.1 - 5e-48 162.9 0.0 6.4e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO27440.1 - 4.1e-13 48.3 0.1 7.3e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nup88 PF10168.4 EGO27441.1 - 2.2e-16 58.8 2.8 9.3e-09 33.7 0.0 2.9 2 1 0 2 2 2 2 Nuclear pore component Hemerythrin PF01814.18 EGO27441.1 - 0.19 11.9 1.9 0.35 11.0 1.3 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Nup54 PF13874.1 EGO27441.1 - 0.48 10.0 7.4 0.27 10.9 3.2 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ribosomal_S3Ae PF01015.13 EGO27442.1 - 1.8e-86 288.4 5.6 2.2e-86 288.2 3.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 EGO27442.1 - 0.058 13.7 0.2 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Abhydro_lipase PF04083.11 EGO27442.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region MFS_1 PF07690.11 EGO27443.1 - 7.9e-41 139.9 47.1 7.9e-41 139.9 32.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EGO27443.1 - 0.00017 19.8 3.8 0.00029 19.0 2.7 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.19 EGO27443.1 - 0.0035 16.0 36.2 0.23 10.0 25.1 3.7 1 1 0 1 1 1 1 Sugar (and other) transporter BacteriocIIc_cy PF12173.3 EGO27443.1 - 0.18 11.8 3.4 1 9.4 0.1 3.5 3 1 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like Gly-zipper_Omp PF13488.1 EGO27443.1 - 3.6 7.2 8.7 0.36 10.4 0.8 2.5 2 0 0 2 2 2 0 Glycine zipper DEAD PF00270.24 EGO27444.1 - 5.3e-46 156.1 0.0 2.3e-45 154.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO27444.1 - 1.4e-23 82.5 0.0 3.5e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO27444.1 - 0.0026 16.5 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGO27444.1 - 0.049 13.4 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PI31_Prot_N PF11566.3 EGO27445.1 - 2.3e-19 69.5 0.0 2.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EGO27445.1 - 1.2e-07 32.3 14.9 1.2e-07 32.3 10.3 2.8 2 1 1 3 3 3 1 PI31 proteasome regulator Glyco_hydro_47 PF01532.15 EGO27446.1 - 2.6e-131 438.4 0.0 3.3e-131 438.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 EGO27446.1 - 3.6e-09 36.2 0.0 7.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 PA domain WD40 PF00400.27 EGO27447.1 - 9.6e-78 253.5 28.3 3.5e-09 36.1 0.1 11.7 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp12 PF04003.7 EGO27447.1 - 2.3e-18 66.1 1.3 4.1e-18 65.2 0.9 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EGO27447.1 - 1e-07 31.1 9.7 0.0085 14.8 0.1 5.9 1 1 3 6 6 6 3 Nup133 N terminal like Nup160 PF11715.3 EGO27447.1 - 6.6e-05 21.2 6.3 2.6 6.0 0.0 5.3 4 1 1 5 5 5 4 Nucleoporin Nup120/160 Med16 PF11635.3 EGO27447.1 - 0.0032 15.5 0.0 0.7 7.7 0.0 3.0 3 0 0 3 3 3 1 Mediator complex subunit 16 Apc4_WD40 PF12894.2 EGO27447.1 - 0.013 15.0 0.0 6.9 6.2 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.17 EGO27447.1 - 0.053 12.9 0.0 3.8 6.8 0.0 2.9 3 0 0 3 3 3 0 CNH domain ATE_C PF04377.10 EGO27449.1 - 8.6e-41 138.9 0.6 1.7e-40 138.0 0.4 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGO27449.1 - 1.9e-20 72.4 4.2 4.1e-20 71.3 2.9 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Sugar_tr PF00083.19 EGO27450.1 - 4.2e-107 358.5 23.8 4.9e-107 358.3 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO27450.1 - 1.5e-24 86.3 35.0 5.3e-18 64.8 7.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGO27450.1 - 0.0027 17.6 4.7 0.15 12.0 0.8 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF697 PF05128.7 EGO27450.1 - 1.7 8.1 6.0 0.91 9.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF697) Sec63 PF02889.11 EGO27451.1 - 4.2e-81 272.6 0.0 5.9e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EGO27451.1 - 1.8e-34 118.6 1.0 6.7e-24 84.2 0.1 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGO27451.1 - 3.8e-07 30.1 0.1 0.024 14.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO27451.1 - 7.8e-06 25.6 0.0 2.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA PF00004.24 EGO27451.1 - 0.00017 21.7 0.3 0.14 12.4 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO27451.1 - 0.0098 16.0 0.1 2.3 8.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain Glyco_transf_4 PF13439.1 EGO27451.1 - 0.077 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Nsp1_C PF05064.8 EGO27452.1 - 5.2e-30 103.4 0.0 1.1e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EGO27452.1 - 5.4e-05 23.3 63.0 0.052 13.7 32.2 3.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region FlaC_arch PF05377.6 EGO27452.1 - 0.19 11.6 0.4 1.7 8.5 0.0 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EGO27452.1 - 0.49 10.6 2.8 25 5.2 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SNAPc19 PF15497.1 EGO27454.1 - 0.054 13.7 0.5 0.062 13.5 0.3 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 RNA_pol_Rpb4 PF03874.11 EGO27454.1 - 0.069 13.1 0.5 0.076 13.0 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF4219 PF13961.1 EGO27455.1 - 0.18 11.2 0.5 0.38 10.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 EGO27456.1 - 0.024 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO27456.1 - 0.084 12.5 0.9 0.88 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO27456.1 - 1.6 8.6 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein Pribosyltran PF00156.22 EGO27457.1 - 7.5e-16 57.9 0.0 1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO27457.1 - 0.0057 15.8 0.0 0.0078 15.4 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase WD40 PF00400.27 EGO27458.1 - 0.041 13.7 0.1 8 6.5 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF3917 PF13055.1 EGO27459.1 - 0.031 14.5 1.1 0.088 13.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) BAP PF06639.6 EGO27459.1 - 0.13 11.9 0.4 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) DUF4651 PF15513.1 EGO27461.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) RINT1_TIP1 PF04437.8 EGO27463.1 - 2.2e-73 247.5 0.0 2.9e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Ribosomal_S14 PF00253.16 EGO27464.1 - 2.8e-17 61.8 0.2 3.8e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MFS_1 PF07690.11 EGO27465.1 - 5.2e-21 74.7 54.4 2e-14 53.0 14.2 4.2 2 2 1 3 3 3 2 Major Facilitator Superfamily SpoVAB PF13782.1 EGO27465.1 - 0.28 11.2 4.9 25 4.9 0.4 3.6 3 0 0 3 3 3 0 Stage V sporulation protein AB 2TM PF13239.1 EGO27465.1 - 4.4 7.4 9.0 0.42 10.7 0.3 3.0 3 0 0 3 3 3 0 2TM domain DUF4231 PF14015.1 EGO27465.1 - 6.4 6.8 13.6 1.7 8.6 0.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) THEG PF14912.1 EGO27467.1 - 0.06 13.8 0.9 0.077 13.5 0.6 1.1 1 0 0 1 1 1 0 Testicular haploid expressed repeat Pkinase PF00069.20 EGO27468.1 - 3.7e-69 232.7 0.0 5e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27468.1 - 1.3e-28 99.7 0.0 2.1e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO27468.1 - 7.1e-09 35.0 0.1 2.5e-06 26.6 0.0 3.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO27468.1 - 0.028 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO27468.1 - 0.042 13.5 0.0 0.79 9.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.12 EGO27469.1 - 7.4e-20 71.0 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding SNARE_assoc PF09335.6 EGO27471.1 - 8.3e-14 51.8 6.7 8.3e-14 51.8 4.6 2.5 2 1 2 4 4 4 1 SNARE associated Golgi protein DUF2910 PF11139.3 EGO27471.1 - 0.00047 19.3 2.9 0.0034 16.5 1.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2910) DUF4140 PF13600.1 EGO27473.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Phage_lysis PF03245.8 EGO27473.1 - 0.072 13.0 0.6 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein MerR-DNA-bind PF09278.6 EGO27473.1 - 0.29 11.5 2.3 0.45 10.9 1.6 1.3 1 0 0 1 1 1 0 MerR, DNA binding PEX11 PF05648.9 EGO27474.1 - 2.7e-11 43.1 0.7 2.4e-05 23.7 0.0 3.0 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.8 EGO27475.1 - 7.8e-10 38.5 0.1 9.3e-10 38.2 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Nop PF01798.13 EGO27480.1 - 3.4e-42 143.2 0.1 5.3e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EGO27480.1 - 1.9e-38 131.6 4.4 4.2e-38 130.5 3.1 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EGO27480.1 - 1.2e-18 66.6 0.1 5.1e-18 64.6 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain Lin-8 PF03353.10 EGO27481.1 - 0.12 11.6 0.1 0.13 11.4 0.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist WD40 PF00400.27 EGO27482.1 - 8.6e-15 53.9 0.2 1.2e-08 34.4 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Mg_trans_NIPA PF05653.9 EGO27484.1 - 2.7e-61 207.1 6.1 2.5e-57 194.1 2.1 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EGO27484.1 - 0.00021 21.4 0.3 0.00021 21.4 0.2 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGO27484.1 - 0.0015 18.5 0.8 0.0015 18.5 0.6 3.3 3 1 0 3 3 3 1 EamA-like transporter family Pkinase PF00069.20 EGO27485.1 - 8.9e-67 224.9 0.0 1.5e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27485.1 - 3.9e-30 104.7 0.0 1.1e-28 100.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO27485.1 - 0.00027 19.9 0.5 0.56 9.1 0.1 2.5 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGO27485.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family PROL5-SMR PF15621.1 EGO27485.1 - 0.6 10.5 7.7 8 6.9 1.7 2.5 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Hydrolase_6 PF13344.1 EGO27486.1 - 1.4e-27 95.5 0.0 2.3e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO27486.1 - 1.4e-16 59.8 0.0 3.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO27486.1 - 6.1e-11 43.1 0.0 8.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO27486.1 - 8.3e-06 26.1 0.0 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.21 EGO27486.1 - 0.0087 15.5 0.1 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PGP_phosphatase PF09419.5 EGO27486.1 - 0.032 13.5 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase AAA_10 PF12846.2 EGO27487.1 - 1.1e-11 44.7 0.0 4e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 EGO27487.1 - 6.9e-06 25.6 0.0 4.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EGO27487.1 - 0.00023 21.2 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EGO27487.1 - 0.00099 19.3 0.0 0.025 14.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EGO27487.1 - 0.067 12.6 0.0 0.96 8.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.12 EGO27487.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2075 PF09848.4 EGO27487.1 - 0.29 10.0 0.0 1.8 7.4 0.0 2.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) Methyltransf_8 PF05148.10 EGO27488.1 - 7.9e-67 225.0 0.0 1.8e-66 223.9 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGO27488.1 - 5.3e-06 26.8 0.1 1.9e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO27488.1 - 7.4e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO27488.1 - 0.0016 18.0 0.0 0.52 9.8 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO27488.1 - 0.013 15.9 0.0 0.061 13.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGO27488.1 - 0.031 14.6 0.1 0.59 10.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGO27488.1 - 0.14 11.8 0.2 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ndc1_Nup PF09531.5 EGO27488.1 - 1.8 6.8 12.1 5.4 5.3 8.6 1.5 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup UPRTase PF14681.1 EGO27489.1 - 4e-67 225.4 0.0 4.5e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FAD_binding_1 PF00667.15 EGO27490.1 - 9.6e-52 175.5 0.0 1.7e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGO27490.1 - 3.1e-09 37.3 0.0 7.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO27490.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain POR PF01558.13 EGO27490.1 - 0.048 13.5 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EGO27490.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain Glyco_hydro_9 PF00759.14 EGO27491.1 - 3.1e-101 339.4 9.0 5.2e-101 338.7 6.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 GFO_IDH_MocA PF01408.17 EGO27492.1 - 5.9e-24 84.8 0.1 1.4e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO27492.1 - 1.8e-07 30.9 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EGO27492.1 - 0.0046 17.2 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Lipocalin_7 PF14651.1 EGO27492.1 - 0.035 13.8 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Apt1 PF10351.4 EGO27493.1 - 1.1e-77 261.8 0.1 1.7e-77 261.2 0.1 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EGO27493.1 - 2.3e-62 210.9 0.0 4.4e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EGO27493.1 - 1.2e-39 135.7 0.0 2.4e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EGO27493.1 - 2e-21 76.3 0.0 5.2e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EGO27493.1 - 2.1e-13 50.5 0.2 1.4e-12 47.9 0.0 2.7 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.11 EGO27494.1 - 1.3e-46 158.5 0.3 2.5e-46 157.5 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 EGO27494.1 - 0.06 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Peptidase_M16 PF00675.15 EGO27494.1 - 0.073 12.8 0.1 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) UPF0183 PF03676.9 EGO27495.1 - 1.1e-48 165.8 0.0 6.6e-37 127.0 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) HAD_2 PF13419.1 EGO27496.1 - 3.1e-08 34.0 0.0 3.2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ribosomal_L6e PF01159.14 EGO27497.1 - 3e-38 130.4 0.1 4.7e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EGO27497.1 - 1.5e-06 28.0 0.1 1.5e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain 60KD_IMP PF02096.15 EGO27498.1 - 1.3e-23 83.7 2.1 9.1e-23 80.9 1.5 2.2 1 1 0 1 1 1 1 60Kd inner membrane protein DUF2062 PF09835.4 EGO27498.1 - 0.066 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Clat_adaptor_s PF01217.15 EGO27499.1 - 6.8e-57 191.1 1.7 8e-57 190.9 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_T PF00929.19 EGO27500.1 - 1.2e-17 64.7 0.0 4.2e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Exonuclease CHORD PF04968.7 EGO27500.1 - 0.019 15.2 2.0 0.033 14.4 1.4 1.4 1 0 0 1 1 1 0 CHORD MCPVI PF02993.9 EGO27500.1 - 4.5 7.3 6.5 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Minor capsid protein VI TRAM_LAG1_CLN8 PF03798.11 EGO27501.1 - 4.1e-31 108.0 26.4 4.1e-31 108.0 18.3 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGO27501.1 - 3.6e-14 52.0 0.7 7.7e-14 50.9 0.5 1.6 1 0 0 1 1 1 1 TRAM1-like protein Histone PF00125.19 EGO27502.1 - 7.5e-29 99.6 0.2 1.4e-28 98.8 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO27502.1 - 0.00041 20.4 0.1 0.00055 20.0 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO27502.1 - 0.0017 18.3 0.9 0.0069 16.4 0.2 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGO27502.1 - 0.013 14.7 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ycf1 PF05758.7 EGO27503.1 - 0.42 8.2 6.1 0.54 7.9 2.4 1.9 2 0 0 2 2 2 0 Ycf1 MAP7 PF05672.6 EGO27503.1 - 6.5 6.1 41.7 13 5.1 28.9 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Borrelia_P83 PF05262.6 EGO27503.1 - 6.6 4.8 11.1 9.4 4.3 7.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DnaJ PF00226.26 EGO27505.1 - 6.4e-15 54.6 0.0 9.6e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain PQQ_3 PF13570.1 EGO27505.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 PQQ-like domain Gln-synt_C PF00120.19 EGO27506.1 - 3e-60 203.5 0.0 3.6e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGO27506.1 - 3e-18 65.1 0.0 4.9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Iso_dh PF00180.15 EGO27507.1 - 4.3e-79 265.9 0.0 5.4e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 EGO27508.1 - 4e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO27508.1 - 0.037 13.7 0.0 0.091 12.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Piwi PF02171.12 EGO27509.1 - 1.4e-87 293.5 0.0 1.8e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGO27509.1 - 1.2e-17 62.9 0.1 3.2e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGO27509.1 - 1.9e-09 36.9 0.0 4.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PAZ domain TspO_MBR PF03073.10 EGO27510.1 - 1.2e-39 135.1 8.6 1.4e-39 134.9 6.0 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1201 PF06716.6 EGO27510.1 - 0.31 10.9 0.1 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Ipi1_N PF12333.3 EGO27511.1 - 5.9e-14 51.8 0.1 5.9e-11 42.2 0.0 3.3 3 1 1 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 EGO27511.1 - 0.023 14.9 0.0 0.4 10.9 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats MMS22L_C PF14911.1 EGO27511.1 - 0.036 13.1 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal DUF531 PF04407.7 EGO27512.1 - 0.025 14.4 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF531) Rab5-bind PF09311.6 EGO27513.1 - 0.024 14.5 0.5 0.024 14.5 0.4 2.2 2 0 0 2 2 2 0 Rabaptin-like protein IncA PF04156.9 EGO27513.1 - 2 7.9 5.2 0.26 10.8 0.1 2.1 3 0 0 3 3 3 0 IncA protein DUF4218 PF13960.1 EGO27514.1 - 0.055 12.9 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Polysacc_deac_1 PF01522.16 EGO27515.1 - 5.7e-21 74.4 0.0 1.1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HLH PF00010.21 EGO27516.1 - 4.6e-14 51.8 0.1 9.7e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.24 EGO27518.1 - 5.9e-07 29.7 0.0 7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGO27518.1 - 4.2e-05 22.4 0.0 4.3e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EGO27518.1 - 0.00028 20.9 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO27518.1 - 0.00085 19.0 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGO27518.1 - 0.0014 19.4 0.1 0.0016 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO27518.1 - 0.0054 15.7 0.0 0.0055 15.7 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGO27518.1 - 0.0056 15.4 0.0 0.0072 15.0 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EGO27518.1 - 0.0091 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EGO27518.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGO27518.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO27518.1 - 0.018 15.3 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGO27518.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EGO27518.1 - 0.029 13.2 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EGO27518.1 - 0.036 14.2 0.0 0.046 13.9 0.0 1.3 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EGO27518.1 - 0.042 13.9 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EGO27518.1 - 0.048 13.2 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO27518.1 - 0.049 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 NTPase DUF815 PF05673.8 EGO27518.1 - 0.053 12.4 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EGO27518.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Cupin_8 PF13621.1 EGO27519.1 - 3.8e-60 203.5 0.0 5.1e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGO27519.1 - 0.0004 19.7 0.2 0.00068 18.9 0.2 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EGO27519.1 - 0.0011 19.1 0.1 0.0035 17.5 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGO27519.1 - 0.0095 15.4 0.1 0.077 12.5 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Ribosomal_L7Ae PF01248.21 EGO27520.1 - 7e-25 86.3 0.7 1.2e-24 85.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1564 PF07600.6 EGO27520.1 - 0.12 11.6 0.3 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Elongin_A PF06881.6 EGO27520.1 - 0.16 12.3 0.2 0.16 12.3 0.1 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RFX_DNA_binding PF02257.10 EGO27521.1 - 6.5e-26 90.3 0.0 2.9e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 RFX DNA-binding domain Metallophos PF00149.23 EGO27522.1 - 6.8e-09 35.4 0.1 1.6e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.23 EGO27524.1 - 1.8e-40 138.6 0.0 2.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF805 PF05656.9 EGO27525.1 - 0.07 12.9 4.6 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Ferric_reduct PF01794.14 EGO27525.1 - 3.2 7.8 7.6 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 Ferric reductase like transmembrane component EamA PF00892.15 EGO27527.1 - 0.0054 16.7 1.8 0.0063 16.5 1.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF4131 PF13567.1 EGO27527.1 - 0.043 13.2 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF443 PF04276.7 EGO27527.1 - 0.31 10.4 5.4 5.4 6.3 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF443) UQ_con PF00179.21 EGO27528.1 - 3.6e-36 123.6 0.3 4.2e-36 123.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FimP PF09766.4 EGO27529.1 - 9.8e-32 110.3 11.2 1.2e-31 110.0 7.8 1.0 1 0 0 1 1 1 1 Fms-interacting protein Pdase_C33_assoc PF14756.1 EGO27529.1 - 0.0025 17.5 0.2 0.88 9.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase_C33-associated domain DUF948 PF06103.6 EGO27529.1 - 0.057 13.2 2.6 0.49 10.2 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.3 EGO27529.1 - 0.21 10.8 6.9 1.5 8.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.4 EGO27529.1 - 0.73 10.0 6.0 4.6 7.4 1.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 EGO27529.1 - 0.8 9.7 7.3 1.1 9.3 0.5 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 EGO27529.1 - 1.7 8.5 12.4 0.46 10.4 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) GCN5L1 PF06320.8 EGO27529.1 - 2.2 8.1 6.6 2.3 8.0 0.6 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) G6PD_C PF02781.11 EGO27530.1 - 1.1e-122 408.5 0.0 1.4e-122 408.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGO27530.1 - 7.3e-62 208.8 0.0 1.1e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DIE2_ALG10 PF04922.7 EGO27531.1 - 6.2e-93 311.8 16.9 7.5e-93 311.5 11.7 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Rpr2 PF04032.11 EGO27533.1 - 0.087 12.7 0.4 0.087 12.7 0.2 1.7 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.1 EGO27533.1 - 0.39 10.2 2.7 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain RNB PF00773.14 EGO27535.1 - 1.3e-93 313.8 0.4 2.8e-93 312.7 0.2 1.7 2 0 0 2 2 2 1 RNB domain T2SF PF00482.18 EGO27535.1 - 0.0022 17.8 0.2 0.0054 16.6 0.2 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Med15 PF09606.5 EGO27535.1 - 2.7 6.1 20.2 4 5.5 14.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Iso_dh PF00180.15 EGO27536.1 - 1.6e-100 336.4 0.0 2e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Snf7 PF03357.16 EGO27537.1 - 2e-27 95.6 17.6 2e-27 95.6 12.2 1.5 1 1 0 1 1 1 1 Snf7 DUF2428 PF10350.4 EGO27537.1 - 0.0018 17.3 0.1 0.0027 16.7 0.1 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) YlqD PF11068.3 EGO27537.1 - 7.8 6.5 16.1 0.38 10.7 5.1 2.7 1 1 2 3 3 3 0 YlqD protein GPI-anchored PF10342.4 EGO27538.1 - 2.9e-12 46.8 0.2 8.6e-12 45.3 0.2 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3643 PF12356.3 EGO27538.1 - 0.17 11.2 0.5 0.33 10.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3643) Fungal_trans PF04082.13 EGO27539.1 - 1.4e-18 66.6 0.1 2.8e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med17 PF10156.4 EGO27540.1 - 2.7e-41 141.3 0.0 3.7e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DMA PF03474.9 EGO27540.1 - 0.0061 16.3 1.0 0.075 12.8 0.1 2.5 2 0 0 2 2 2 1 DMRTA motif Ribosomal_L18p PF00861.17 EGO27541.1 - 2.4e-42 143.8 0.0 4.1e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGO27541.1 - 6.4e-33 113.1 1.6 6.4e-33 113.1 1.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Peripla_BP_5 PF13433.1 EGO27541.1 - 0.074 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain RRM_1 PF00076.17 EGO27542.1 - 1.8e-15 56.3 0.1 2.6e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27542.1 - 7.7e-11 41.8 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27542.1 - 0.00048 19.9 0.1 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 EGO27543.1 - 9.2e-29 99.2 0.3 5.2e-28 96.7 0.0 2.5 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EGO27543.1 - 0.00098 19.3 0.2 1.1 9.5 0.1 3.6 2 2 2 4 4 4 1 HEAT repeats Arm PF00514.18 EGO27543.1 - 0.0023 17.6 0.4 0.016 15.0 0.0 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 EGO27543.1 - 0.0076 15.9 1.0 0.49 10.0 0.0 3.3 1 1 2 3 3 3 1 Myosin-binding striated muscle assembly central WD40 PF00400.27 EGO27544.1 - 0.0012 18.6 0.3 0.12 12.2 0.1 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat Thioredoxin PF00085.15 EGO27545.1 - 2.4e-57 191.0 0.0 2.5e-31 107.4 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EGO27545.1 - 8.5e-45 152.8 0.0 1.4e-34 119.5 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGO27545.1 - 1.7e-09 37.6 0.1 0.002 18.2 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EGO27545.1 - 4.7e-09 36.1 0.1 0.0048 16.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGO27545.1 - 2.2e-08 34.2 0.3 0.0014 18.8 0.1 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EGO27545.1 - 7.7e-05 22.3 0.1 0.05 13.2 0.0 3.3 3 0 0 3 3 3 1 AhpC/TSA family Calsequestrin PF01216.12 EGO27545.1 - 0.00018 20.4 0.0 0.00036 19.4 0.0 1.5 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 EGO27545.1 - 0.0062 16.0 0.3 0.53 9.8 0.1 3.0 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.1 EGO27545.1 - 0.024 14.4 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EGO27545.1 - 0.11 12.4 0.2 4.1 7.3 0.1 3.1 3 1 0 3 3 3 0 Thioredoxin FAT PF02259.18 EGO27547.1 - 1.9e-70 237.6 6.9 3.8e-70 236.6 4.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGO27547.1 - 2.1e-15 56.8 0.0 6.1e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_11 PF13414.1 EGO27547.1 - 0.0029 17.2 0.7 0.069 12.8 0.0 2.9 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 EGO27547.1 - 0.077 12.8 0.1 3.1 7.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO27547.1 - 0.081 12.8 2.3 18 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Radial_spoke_3 PF06098.6 EGO27547.1 - 0.2 10.5 0.2 0.39 9.6 0.1 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 TPR_14 PF13428.1 EGO27547.1 - 0.21 12.3 4.5 6.7 7.6 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Bromodomain PF00439.20 EGO27548.1 - 2.2e-24 85.1 0.2 3.7e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Bromodomain Asp PF00026.18 EGO27549.1 - 1.1e-111 373.0 0.4 1.3e-111 372.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO27549.1 - 7.3e-09 35.7 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO27549.1 - 3.2e-06 27.5 0.0 0.01 16.3 0.0 2.9 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EGO27549.1 - 5.8e-06 25.9 0.0 0.00015 21.3 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal WD40 PF00400.27 EGO27550.1 - 5.1e-26 89.5 2.4 3.3e-10 39.4 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2722 PF10846.3 EGO27550.1 - 0.032 13.2 0.7 0.046 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIIC_delta PF12657.2 EGO27550.1 - 0.085 12.5 0.1 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Nucleoplasmin PF03066.10 EGO27550.1 - 0.25 10.8 9.1 0.41 10.1 6.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin PPP4R2 PF09184.6 EGO27550.1 - 0.31 10.5 7.7 0.51 9.8 5.3 1.2 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.11 EGO27550.1 - 1.4 7.8 4.2 2.2 7.2 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 EGO27550.1 - 6 6.0 7.8 9.5 5.3 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EGO27550.1 - 7.7 6.0 9.8 12 5.4 6.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PCI PF01399.22 EGO27551.1 - 4.4e-10 39.8 0.0 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EGO27551.1 - 0.006 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EGO27551.1 - 0.047 14.3 0.9 22 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO27551.1 - 0.081 12.8 2.0 0.28 11.1 0.6 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO27551.1 - 0.1 12.4 1.2 14 5.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LSPR PF06049.7 EGO27552.1 - 0.0055 15.8 1.4 8.8 6.2 0.1 3.9 2 0 0 2 2 2 2 Coagulation Factor V LSPD Repeat DUF3336 PF11815.3 EGO27553.1 - 5.3e-41 139.5 6.2 7.8e-41 138.9 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGO27553.1 - 2.5e-20 73.2 0.1 5.4e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3759 PF12585.3 EGO27554.1 - 9.3e-38 128.0 7.2 1.2e-37 127.6 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF4481 PF14800.1 EGO27554.1 - 0.073 11.9 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF3759 PF12585.3 EGO27555.1 - 3.9e-38 129.2 9.1 4.7e-38 128.9 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3813 PF12758.2 EGO27555.1 - 0.058 13.5 0.2 0.058 13.5 0.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3813) DUF4481 PF14800.1 EGO27555.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DivIVA PF05103.8 EGO27555.1 - 0.9 9.5 4.7 1.9 8.5 3.3 1.6 1 1 0 1 1 1 0 DivIVA protein ORC4_C PF14629.1 EGO27556.1 - 1.5e-25 89.8 0.0 2.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EGO27556.1 - 2.5e-12 47.1 4.1 7.5e-11 42.3 2.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EGO27556.1 - 0.046 13.9 0.2 5 7.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Med20 PF08612.6 EGO27557.1 - 4.9e-09 35.6 0.0 0.00057 19.1 0.0 2.1 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BCDHK_Adom3 PF10436.4 EGO27558.1 - 5.3e-36 123.6 0.0 8.1e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGO27558.1 - 1.9e-11 43.6 0.0 3.2e-10 39.6 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGO27558.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 EGO27561.1 - 1.8e-63 214.1 0.2 3.6e-42 144.3 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27561.1 - 8.5e-28 97.1 0.2 8.9e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO27561.1 - 0.00019 20.5 0.0 0.0005 19.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO27561.1 - 0.00025 20.2 0.0 0.00089 18.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EGO27561.1 - 0.0015 19.0 0.1 0.0031 18.0 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EGO27561.1 - 0.0024 17.6 0.2 0.028 14.1 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGO27561.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EGO27561.1 - 0.022 14.0 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EGO27561.1 - 0.037 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.24 EGO27562.1 - 2.1e-19 69.6 0.1 2.4e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO27562.1 - 0.00016 21.5 0.0 0.00018 21.3 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO27562.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain DUF4137 PF13593.1 EGO27562.1 - 0.0029 16.7 0.1 0.0032 16.6 0.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) UvrD-helicase PF00580.16 EGO27562.1 - 0.0043 16.3 0.1 0.0047 16.2 0.1 1.0 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SecA_DEAD PF07517.9 EGO27562.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain DUF4217 PF13959.1 EGO27563.1 - 2.1e-23 81.6 0.1 4.5e-23 80.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Pox_RNA_Pol_19 PF05320.7 EGO27563.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HTH_30 PF13556.1 EGO27563.1 - 0.045 13.3 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF3832 PF12909.2 EGO27563.1 - 0.065 13.2 0.1 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) PTPlike_phytase PF14566.1 EGO27563.1 - 0.12 12.3 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3818 PF12825.2 EGO27564.1 - 2.7e-111 371.5 0.2 3.8e-111 371.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGO27564.1 - 1.5e-26 92.6 0.3 4.8e-26 90.9 0.2 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EGO27564.1 - 4.5e-10 39.3 0.2 3.8e-09 36.3 0.0 2.7 2 1 0 2 2 2 1 PX domain DUF1682 PF07946.9 EGO27566.1 - 7.7e-72 241.8 0.1 8.7e-72 241.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Tim17 PF02466.14 EGO27569.1 - 1.9e-12 47.3 13.0 2.8e-12 46.8 9.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EGO27569.1 - 0.00024 21.1 2.4 0.00024 21.1 1.7 3.0 2 1 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide MtrF PF09472.5 EGO27569.1 - 0.18 11.0 1.3 7.7 5.8 0.0 2.7 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Gly-zipper_OmpA PF13436.1 EGO27569.1 - 7.1 6.3 19.5 0.77 9.4 3.2 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain LON PF02190.11 EGO27570.1 - 2.3e-18 66.6 0.0 4.9e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_5 PF14634.1 EGO27570.1 - 2.9e-08 33.2 26.1 4e-06 26.4 7.9 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO27570.1 - 1.3e-07 31.1 26.0 1.6e-07 30.8 8.1 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO27570.1 - 3.3e-07 30.2 27.8 1e-06 28.6 8.2 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO27570.1 - 3.8e-07 29.8 12.2 3.8e-07 29.8 8.5 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGO27570.1 - 5.9e-07 29.2 27.5 0.00067 19.4 9.1 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EGO27570.1 - 1.1e-06 28.1 7.9 1.1e-06 28.1 5.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGO27570.1 - 0.011 15.2 2.8 0.011 15.2 2.0 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain U-box PF04564.10 EGO27570.1 - 0.13 12.2 1.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 U-box domain zf-P11 PF03854.9 EGO27570.1 - 0.22 11.0 12.6 0.021 14.2 4.6 2.4 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.1 EGO27570.1 - 1.5 8.6 12.8 0.072 12.8 1.1 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGO27570.1 - 8.9 6.1 30.2 0.053 13.2 6.1 3.1 3 0 0 3 3 2 0 RING-type zinc-finger RTA1 PF04479.8 EGO27571.1 - 4.7e-41 140.7 1.5 7.4e-41 140.0 1.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Anophelin PF10731.4 EGO27571.1 - 0.15 12.1 0.1 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito VID27 PF08553.5 EGO27573.1 - 1.1e-257 857.3 1.7 1.2e-257 857.1 1.2 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2834 PF11196.3 EGO27574.1 - 0.085 13.0 2.6 0.16 12.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) CRCB PF02537.10 EGO27576.1 - 1.8e-32 111.6 18.0 1.1e-20 73.6 4.0 2.6 3 1 0 3 3 3 2 CrcB-like protein DUF3733 PF12534.3 EGO27576.1 - 0.072 12.3 1.5 0.14 11.4 1.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 Ribosomal_L36e PF01158.13 EGO27577.1 - 1.9e-39 133.5 2.5 2.1e-39 133.4 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e SNARE_assoc PF09335.6 EGO27578.1 - 1.8e-16 60.4 4.3 1.8e-16 60.4 3.0 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein Mito_carr PF00153.22 EGO27579.1 - 1.2e-64 213.9 4.2 3.4e-23 81.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EGO27579.1 - 0.00099 18.2 0.0 0.045 13.0 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EGO27579.1 - 0.0019 18.3 0.0 0.0094 16.0 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGO27579.1 - 0.0021 17.7 0.0 0.07 13.0 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EGO27579.1 - 0.032 13.5 0.6 0.088 12.1 0.1 2.0 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EGO27579.1 - 0.11 12.0 0.1 8.8 6.0 0.0 3.3 3 1 2 5 5 5 0 EF-hand domain pair Amidohydro_2 PF04909.9 EGO27580.1 - 1.3e-27 97.0 0.2 1.6e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.20 EGO27581.1 - 6.1e-33 114.0 0.1 2.1e-32 112.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO27581.1 - 1.7e-17 63.6 0.1 3.2e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO27581.1 - 2.1e-17 63.7 0.0 2.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO27581.1 - 7.8e-08 32.5 0.0 1.4e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO27581.1 - 0.00032 20.1 0.0 0.00083 18.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO27581.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGO27581.1 - 0.019 13.9 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase YjeF_N PF03853.10 EGO27581.1 - 0.044 13.3 0.1 0.18 11.3 0.0 1.9 2 1 0 2 2 2 0 YjeF-related protein N-terminus Sec23_trunk PF04811.10 EGO27581.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Transket_pyr PF02779.19 EGO27582.1 - 1.9e-46 157.8 0.0 3.3e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGO27582.1 - 9.4e-40 135.3 0.1 3.1e-39 133.7 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Histidinol_dh PF00815.15 EGO27583.1 - 3.2e-175 582.6 0.8 4.4e-175 582.2 0.6 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EGO27583.1 - 1.8e-25 88.3 0.1 4.1e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EGO27583.1 - 1.5e-08 34.7 1.0 3.5e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase PepSY_TM_1 PF13172.1 EGO27584.1 - 5.2 6.9 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix Snf7 PF03357.16 EGO27585.1 - 7.6e-34 116.5 23.0 7.6e-34 116.5 16.0 1.3 1 1 0 1 1 1 1 Snf7 SPOB_a PF14689.1 EGO27585.1 - 0.031 13.8 2.3 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Birna_RdRp PF04197.7 EGO27585.1 - 0.47 8.4 7.1 0.5 8.3 4.9 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) PLRV_ORF5 PF01690.12 EGO27585.1 - 1.5 7.9 7.4 1.8 7.5 5.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Atg14 PF10186.4 EGO27585.1 - 7.2 5.4 14.4 31 3.3 10.0 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TRAM_LAG1_CLN8 PF03798.11 EGO27586.1 - 2.8e-45 154.3 24.6 4.1e-45 153.7 17.0 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EGO27586.1 - 1.1e-07 31.2 0.2 3.6e-07 29.5 0.2 1.9 1 0 0 1 1 1 1 TRAM1-like protein PSI_8 PF00796.13 EGO27586.1 - 0.054 13.0 1.2 0.16 11.5 0.8 1.9 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII DUF2215 PF10225.4 EGO27586.1 - 0.23 10.8 0.0 0.23 10.8 0.0 3.0 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2215) RRM_1 PF00076.17 EGO27587.1 - 8e-16 57.4 0.0 9.7e-07 28.3 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27587.1 - 5.8e-11 42.0 0.0 8.3e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27587.1 - 4.7e-10 39.3 0.0 0.00055 19.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.3 EGO27587.1 - 0.00074 18.2 1.5 0.001 17.7 1.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Radial_spoke PF04712.7 EGO27587.1 - 0.00074 18.3 0.7 0.00085 18.1 0.5 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein CDC45 PF02724.9 EGO27587.1 - 0.13 10.2 3.0 0.17 9.9 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DJ-1_PfpI PF01965.19 EGO27588.1 - 1.4e-24 86.2 0.3 2.1e-24 85.6 0.2 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EGO27588.1 - 5.9e-12 44.9 0.2 1.7e-11 43.4 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Mob1_phocein PF03637.12 EGO27589.1 - 3.6e-74 248.1 0.0 4.2e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.24 EGO27591.1 - 9.1e-43 145.6 0.0 1.7e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO27591.1 - 2.4e-24 85.0 0.0 4.9e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO27591.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HMG_box PF00505.14 EGO27592.1 - 2.6e-13 50.0 0.5 4.5e-13 49.2 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Sua5_yciO_yrdC PF01300.13 EGO27593.1 - 8.3e-51 171.7 0.0 1.9e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGO27593.1 - 8.6e-27 93.7 0.0 1.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Complex1_LYR_2 PF13233.1 EGO27594.1 - 4.3e-09 36.7 0.1 8.1e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like FadR_C PF07840.7 EGO27594.1 - 0.04 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 FadR C-terminal domain RRM_1 PF00076.17 EGO27595.1 - 1.4e-09 37.4 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27595.1 - 4.7e-08 32.8 0.0 2.4e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EGO27595.1 - 0.0041 16.8 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EGO27595.1 - 0.011 15.5 0.0 0.12 12.2 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 EGO27596.1 - 7.2e-15 54.8 0.0 3.2e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO27596.1 - 1.1e-08 34.7 0.0 2.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 EGO27597.1 - 5e-68 222.7 27.8 1.4e-09 37.4 0.5 12.0 11 1 1 12 12 12 11 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGO27597.1 - 0.029 13.8 0.1 20 4.8 0.0 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EGO27597.1 - 0.13 11.9 0.4 39 3.8 0.0 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A GCV_T PF01571.16 EGO27598.1 - 6.2e-17 61.6 0.0 9.1e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGO27598.1 - 3.3e-05 23.8 0.0 9.9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain YppF PF14178.1 EGO27598.1 - 0.17 11.4 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 YppF-like protein GST_N_3 PF13417.1 EGO27599.1 - 3e-11 43.3 0.0 5.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO27599.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO27599.1 - 1.9e-09 37.5 0.0 5.3e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO27599.1 - 9.8e-08 31.8 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO27599.1 - 1.9e-07 30.8 0.0 3.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1640 PF07798.6 EGO27600.1 - 7.9e-14 52.0 6.4 9.9e-14 51.7 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.8 EGO27600.1 - 0.37 10.1 3.9 0.62 9.4 2.6 1.4 1 1 0 1 1 1 0 fzo-like conserved region Mago-bind PF09282.5 EGO27601.1 - 7.1e-13 47.8 2.4 1.4e-12 46.9 1.7 1.5 1 0 0 1 1 1 1 Mago binding Pox_Ag35 PF03286.9 EGO27601.1 - 0.027 13.9 7.2 0.034 13.6 5.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BSP_II PF05432.6 EGO27601.1 - 0.36 10.0 8.9 0.47 9.6 6.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 EGO27601.1 - 0.59 10.4 8.0 1 9.6 5.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 EGO27601.1 - 2.1 8.0 5.8 3.2 7.4 4.0 1.3 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.11 EGO27601.1 - 8.4 6.1 5.7 12 5.7 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP_bind_1 PF03029.12 EGO27602.1 - 1.2e-73 247.6 0.0 1.5e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGO27602.1 - 7e-05 23.6 0.0 0.00013 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EGO27602.1 - 0.00044 19.6 0.0 0.001 18.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EGO27602.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase ArgK PF03308.11 EGO27602.1 - 0.0049 15.6 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EGO27602.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EGO27602.1 - 0.0061 16.0 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGO27602.1 - 0.0091 16.1 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO27602.1 - 0.017 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGO27602.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EGO27602.1 - 0.024 14.5 0.0 0.072 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGO27602.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EGO27602.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EGO27602.1 - 0.051 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EGO27602.1 - 0.061 13.0 0.0 0.3 10.7 0.0 2.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EGO27602.1 - 0.063 12.3 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EGO27602.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.5 EGO27602.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EGO27602.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGO27602.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EGO27602.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGO27602.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EGO27602.1 - 0.17 11.5 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 1 0 NTPase APC_crr PF05923.7 EGO27603.1 - 0.11 12.1 2.2 0.47 10.1 0.1 2.5 2 0 0 2 2 2 0 APC cysteine-rich region Ssu72 PF04722.8 EGO27604.1 - 4.1e-81 270.9 0.0 4.9e-81 270.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein EF-hand_1 PF00036.27 EGO27606.1 - 5.9e-24 81.5 11.4 8.6e-08 30.9 0.2 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EGO27606.1 - 1.4e-23 82.7 5.2 6.9e-14 51.7 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO27606.1 - 1.2e-19 68.3 6.4 3.6e-06 26.4 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EGO27606.1 - 2.2e-12 45.7 8.9 0.00041 19.5 0.7 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGO27606.1 - 8.9e-11 41.2 9.4 7.5e-05 22.2 0.7 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EGO27606.1 - 4.6e-08 32.7 4.7 0.0093 15.6 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGO27606.1 - 0.00036 20.5 2.7 0.047 13.7 0.2 3.5 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGO27606.1 - 0.013 15.3 1.4 1.2 9.0 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 EGO27606.1 - 0.037 13.7 1.4 42 3.8 0.0 4.0 4 0 0 4 4 4 0 EF hand S10_plectin PF03501.10 EGO27606.1 - 0.055 13.3 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 EGO27606.1 - 0.081 13.0 0.0 2 8.5 0.0 2.7 3 0 0 3 3 3 0 EF hand Brix PF04427.13 EGO27607.1 - 1.8e-49 167.9 0.3 2.5e-49 167.5 0.2 1.2 1 0 0 1 1 1 1 Brix domain Ribonuc_red_sm PF00268.16 EGO27608.1 - 1.5e-120 401.4 0.8 1.9e-120 401.1 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Fungal_trans PF04082.13 EGO27609.1 - 6.3e-26 90.7 0.2 1.3e-25 89.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO27609.1 - 1.1e-05 25.1 11.1 2.2e-05 24.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGO27613.1 - 2.8e-05 23.4 0.0 0.0036 16.4 0.0 2.8 1 1 0 2 2 2 2 Protein kinase domain LNS2 PF08235.8 EGO27614.1 - 1.3e-71 239.2 0.2 2.4e-71 238.3 0.0 1.5 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGO27614.1 - 1e-31 108.8 0.0 3.4e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EGO27614.1 - 0.072 12.4 0.1 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.10 EGO27615.1 - 1.3e-08 34.5 0.4 2e-08 33.9 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO27615.1 - 2.1e-07 31.0 0.6 3.3e-07 30.3 0.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like RRN3 PF05327.6 EGO27616.1 - 5.8e-157 523.2 0.4 1.5e-156 521.8 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 RicinB_lectin_2 PF14200.1 EGO27620.1 - 2.7e-09 37.3 4.1 2e-05 24.8 0.8 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like RbsD_FucU PF05025.8 EGO27621.1 - 0.045 14.0 1.0 0.082 13.2 0.7 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family IU_nuc_hydro PF01156.14 EGO27625.1 - 1.7e-91 306.7 0.1 1.9e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MCM PF00493.18 EGO27626.1 - 3.6e-136 453.3 0.5 5.3e-136 452.7 0.3 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO27626.1 - 1.3e-24 86.9 0.1 4e-24 85.4 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO27626.1 - 9.8e-08 31.4 0.0 1.3e-06 27.7 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGO27626.1 - 0.0023 17.4 0.0 0.0057 16.1 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EGO27626.1 - 0.0031 17.1 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO27626.1 - 0.014 15.0 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Y_phosphatase3 PF13350.1 EGO27627.1 - 3.3e-47 160.7 0.0 5.1e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO27627.1 - 8.5e-14 51.4 0.2 1.6e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGO27627.1 - 0.00039 19.8 0.0 0.00057 19.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGO27627.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 EGO27627.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DivIC PF04977.10 EGO27627.1 - 0.13 11.7 0.1 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Septum formation initiator Vac14_Fig4_bd PF11916.3 EGO27628.1 - 8.9e-82 272.6 6.7 1.5e-81 271.8 4.6 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EGO27628.1 - 4e-42 142.5 0.1 9.8e-37 125.2 0.0 3.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGO27628.1 - 3e-12 45.5 2.5 0.0012 18.7 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EGO27628.1 - 2.2e-07 31.0 0.1 3.5 7.9 0.0 4.9 4 1 0 4 4 4 3 HEAT repeats MMS19_C PF12460.3 EGO27628.1 - 1e-05 24.4 4.7 0.57 8.8 0.0 4.1 4 1 0 4 4 4 3 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 EGO27628.1 - 8.3e-05 22.9 0.2 19 5.8 0.0 6.3 6 1 1 7 7 7 0 HEAT-like repeat ParcG PF10274.4 EGO27628.1 - 0.0023 17.8 1.1 2.4 8.0 0.1 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein DUF2120 PF09893.4 EGO27628.1 - 0.12 12.3 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) RWD PF05773.17 EGO27629.1 - 8.4e-16 57.8 0.5 1.5e-15 57.0 0.3 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EGO27629.1 - 2.4e-15 56.1 40.2 1.4e-09 37.6 4.2 4.3 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGO27629.1 - 9.9e-06 25.2 9.2 9.9e-06 25.2 6.3 4.7 4 1 1 5 5 5 2 Ring finger domain zf-RING_5 PF14634.1 EGO27629.1 - 0.00049 19.7 7.6 0.00049 19.7 5.2 4.3 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO27629.1 - 0.0046 16.9 7.8 0.0046 16.9 5.4 5.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO27629.1 - 0.0079 15.8 5.2 0.0079 15.8 3.6 5.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.8 EGO27629.1 - 5.8 7.0 16.5 0.72 9.9 3.6 3.3 3 0 0 3 3 3 0 Piccolo Zn-finger Glyco_hydro_3 PF00933.16 EGO27630.1 - 1.4e-73 247.5 0.0 2.1e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO27630.1 - 8.4e-67 225.0 0.0 7.5e-66 221.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO27630.1 - 1e-25 89.4 0.2 1.2e-24 86.0 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EGO27630.1 - 5.5e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain FAD_binding_4 PF01565.18 EGO27630.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain zf-C3HC4_2 PF13923.1 EGO27631.1 - 1.6e-08 34.4 16.6 1.6e-08 34.4 11.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO27631.1 - 1e-06 28.3 18.8 3e-05 23.5 7.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO27631.1 - 1.3e-05 24.7 20.4 0.0001 21.9 8.9 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO27631.1 - 8.6e-05 22.2 26.2 0.00012 21.8 11.1 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGO27631.1 - 0.00014 21.4 14.6 0.00014 21.4 10.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 EGO27631.1 - 0.051 13.7 3.4 20 5.4 0.0 3.9 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EGO27631.1 - 0.064 12.8 2.3 8.8 6.0 0.0 3.5 3 0 0 3 3 3 0 GAGA factor zf-C3HC4_4 PF15227.1 EGO27631.1 - 0.47 10.3 18.5 1.4 8.8 8.6 3.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EGO27631.1 - 0.52 9.8 14.1 0.15 11.5 4.5 2.9 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGO27631.1 - 4.3 7.1 17.2 0.14 11.9 6.4 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 EGO27631.1 - 4.4 6.8 10.1 2.5 7.6 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif Tom7 PF08038.7 EGO27632.1 - 4.3e-18 64.4 0.8 4.9e-18 64.2 0.5 1.1 1 0 0 1 1 1 1 TOM7 family JAB PF01398.16 EGO27633.1 - 1.2e-19 70.1 0.2 2.5e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGO27633.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Glu_cys_ligase PF04262.9 EGO27633.1 - 0.13 10.7 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase AFG1_ATPase PF03969.11 EGO27634.1 - 2.4e-97 326.0 0.0 1.1e-93 313.9 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EGO27634.1 - 0.00046 20.2 0.2 0.4 10.6 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGO27634.1 - 0.0072 16.4 0.1 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO27634.1 - 0.009 16.2 0.0 0.043 14.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EGO27634.1 - 0.091 12.3 0.4 0.6 9.7 0.1 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein ABM PF03992.11 EGO27635.1 - 3.1e-05 23.9 0.0 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SBDS PF01172.13 EGO27636.1 - 2.4e-16 59.2 0.1 3.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MutL_C PF08676.6 EGO27637.1 - 2.1e-05 24.1 0.1 4.7e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EGO27638.1 - 1.7e-09 37.4 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGO27638.1 - 1.6e-07 30.9 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carboxyl_trans PF01039.17 EGO27639.1 - 5.2e-138 460.4 0.3 6.4e-138 460.1 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGO27639.1 - 0.00078 18.7 1.4 0.2 10.8 0.0 2.5 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) ArfGap PF01412.13 EGO27640.1 - 1.4e-32 111.8 0.0 2.6e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Velvet PF11754.3 EGO27641.1 - 1.5e-52 178.2 0.0 4.2e-51 173.4 0.0 2.2 1 1 0 1 1 1 1 Velvet factor PPR_3 PF13812.1 EGO27642.1 - 7.6e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGO27642.1 - 0.0041 17.0 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 EGO27642.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TPR_14 PF13428.1 EGO27642.1 - 0.057 14.0 0.0 0.12 13.0 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HD_3 PF13023.1 EGO27642.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 HD domain HMG_box_2 PF09011.5 EGO27645.1 - 3.6e-15 56.0 11.0 3.8e-07 30.3 0.8 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EGO27645.1 - 5.4e-14 52.2 16.2 7.5e-07 29.3 3.6 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box DUF1289 PF06945.8 EGO27645.1 - 0.16 11.4 0.1 0.5 9.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) GRIM-19 PF06212.7 EGO27647.1 - 1.7e-31 108.6 0.0 2.1e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein bZIP_1 PF00170.16 EGO27648.1 - 0.067 13.1 3.9 0.11 12.4 2.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor Fer4 PF00037.22 EGO27650.1 - 5.4e-14 51.1 17.4 1.7e-08 33.6 3.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGO27650.1 - 5.1e-12 45.9 10.7 9.3e-12 45.1 7.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGO27650.1 - 2.9e-10 39.9 0.5 0.0001 22.2 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGO27650.1 - 3.2e-10 40.5 6.9 8.2e-05 23.2 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EGO27650.1 - 9.3e-10 38.1 22.2 4.6e-08 32.7 8.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGO27650.1 - 1.8e-09 37.6 10.0 3.4e-09 36.8 6.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGO27650.1 - 4.5e-09 36.0 32.7 7.1e-06 25.7 8.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGO27650.1 - 7.9e-09 34.9 14.0 7.1e-05 22.4 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EGO27650.1 - 6.6e-08 32.0 18.0 0.00074 19.2 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGO27650.1 - 2.7e-07 30.8 25.8 0.00019 21.7 6.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EGO27650.1 - 2.1e-06 27.6 12.0 0.00065 19.8 2.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EGO27650.1 - 2.2e-05 24.7 9.6 0.011 16.0 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGO27650.1 - 0.00022 21.5 11.9 0.055 13.8 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGO27650.1 - 0.0021 18.5 12.3 0.15 12.6 0.9 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGO27650.1 - 0.035 14.6 18.1 0.079 13.5 3.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EGO27650.1 - 0.059 13.4 4.1 0.19 11.8 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Prefoldin_2 PF01920.15 EGO27651.1 - 1.3e-21 76.2 0.6 1.7e-21 75.9 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 EGO27651.1 - 0.0089 15.7 0.7 0.017 14.8 0.2 1.6 2 0 0 2 2 2 1 DASH complex subunit Dad3 Prefoldin PF02996.12 EGO27651.1 - 0.037 13.6 0.5 0.18 11.4 0.3 1.8 1 1 0 1 1 1 0 Prefoldin subunit LXG PF04740.7 EGO27651.1 - 0.062 13.0 1.0 1.9 8.2 0.1 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily IncA PF04156.9 EGO27651.1 - 0.14 11.7 1.9 0.57 9.7 1.3 1.8 1 1 0 1 1 1 0 IncA protein GAS PF13851.1 EGO27651.1 - 0.16 11.1 2.5 1.6 7.8 0.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EGO27651.1 - 0.24 11.2 2.4 4 7.2 0.7 2.1 2 0 0 2 2 2 0 Tropomyosin like Spc24 PF08286.6 EGO27651.1 - 0.31 10.7 1.7 0.43 10.2 0.3 1.7 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 CAP PF00188.21 EGO27652.1 - 1.1e-16 61.4 0.3 1.4e-16 61.0 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family F-box PF00646.28 EGO27653.1 - 1.4e-06 27.8 1.8 6.6e-06 25.6 0.6 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGO27653.1 - 1.8e-05 24.3 1.0 1.8e-05 24.3 0.7 1.9 2 0 0 2 2 2 1 F-box-like zf-H2C2_2 PF13465.1 EGO27654.1 - 1.3e-09 37.8 14.7 0.00088 19.4 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGO27654.1 - 3e-07 30.3 15.6 7.1e-05 22.9 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO27654.1 - 8.4e-06 25.7 13.4 0.0091 16.2 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO27654.1 - 0.004 17.2 2.8 0.014 15.5 0.0 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO27654.1 - 3 8.1 6.8 1.1 9.5 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RAP1 PF07218.6 EGO27654.1 - 4.3 5.3 6.0 4.9 5.1 4.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UCH PF00443.24 EGO27655.1 - 6.6e-22 77.8 0.0 8.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO27655.1 - 7.7e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PP2C PF00481.16 EGO27656.1 - 4.2e-29 101.7 0.0 4.9e-26 91.6 0.0 2.7 1 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGO27656.1 - 5.2e-09 35.8 0.0 1.6e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Phage_CII PF05269.6 EGO27658.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CII protein ACT_7 PF13840.1 EGO27659.1 - 2.9e-19 68.3 0.0 2.9e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EGO27659.1 - 0.017 14.5 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 ACT domain CcdB PF01845.12 EGO27659.1 - 0.097 12.6 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 CcdB protein adh_short PF00106.20 EGO27661.1 - 8.2e-31 107.1 0.2 2.1e-30 105.8 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO27661.1 - 4.8e-12 45.9 0.9 1.1e-10 41.5 0.6 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO27661.1 - 4e-10 39.8 0.0 5.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO27661.1 - 0.0021 18.0 0.1 0.0045 17.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO27661.1 - 0.0086 15.5 0.2 0.016 14.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SKN1 PF03935.10 EGO27663.1 - 1.9e-163 544.2 8.2 2.4e-163 543.9 5.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_M22 PF00814.20 EGO27664.1 - 6e-84 281.6 0.0 7.1e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Pex14_N PF04695.8 EGO27665.1 - 1.3e-10 41.4 2.2 2.3e-09 37.4 0.0 2.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Fun_ATP-synt_8 PF05933.8 EGO27665.1 - 0.06 13.3 0.5 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) F-box-like PF12937.2 EGO27667.1 - 5.3e-05 22.8 2.2 0.00018 21.1 1.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGO27667.1 - 0.0037 16.8 4.4 3 7.5 0.0 4.3 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EGO27667.1 - 0.0092 15.6 0.4 0.0092 15.6 0.3 2.3 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EGO27667.1 - 0.013 15.2 3.0 25 4.7 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 EGO27667.1 - 0.034 14.3 3.6 28 5.5 0.0 5.8 7 0 0 7 7 7 0 Leucine rich repeat LRR_2 PF07723.8 EGO27667.1 - 0.077 13.5 1.1 13 6.4 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_1 PF00560.28 EGO27667.1 - 0.16 12.1 4.8 15 6.0 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat TFR_dimer PF04253.10 EGO27668.1 - 7.2e-15 54.6 0.0 2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGO27668.1 - 6e-14 52.1 0.0 1.3e-12 47.8 0.0 2.7 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EGO27668.1 - 1e-07 31.5 0.1 2.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EGO27668.1 - 0.011 15.0 0.0 0.026 13.7 0.0 1.6 1 0 0 1 1 1 0 Nicastrin Spectrin PF00435.16 EGO27668.1 - 0.035 14.3 1.4 0.096 12.9 1.0 1.7 1 0 0 1 1 1 0 Spectrin repeat DUF1466 PF07326.6 EGO27668.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) Alpha-amylase_C PF02806.13 EGO27669.1 - 3.4e-24 84.8 0.1 2.3e-23 82.1 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EGO27669.1 - 1.3e-17 63.5 0.0 3.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 EGO27669.1 - 1.7e-17 63.8 0.1 8e-14 51.7 0.0 3.2 2 1 1 3 3 3 2 Alpha amylase, catalytic domain DUF3635 PF12330.3 EGO27670.1 - 1.2e-17 63.7 1.1 1.9e-17 63.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase_Tyr PF07714.12 EGO27670.1 - 0.071 12.1 0.0 0.65 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Sld5 PF05916.6 EGO27671.1 - 8.8e-18 64.5 0.3 1.3e-17 64.0 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein DUF790 PF05626.6 EGO27671.1 - 0.05 12.1 0.0 0.061 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) P21-Arc PF04062.9 EGO27673.1 - 4.6e-80 267.4 0.0 5.1e-80 267.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Iso_dh PF00180.15 EGO27674.1 - 2.7e-121 404.7 0.0 3.4e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps5 PF09325.5 EGO27675.1 - 9e-21 74.2 3.7 1.2e-20 73.8 2.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGO27675.1 - 5.4e-12 45.4 0.3 1.8e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 PX domain TPR_12 PF13424.1 EGO27675.1 - 0.2 11.6 1.5 2.5 8.1 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4200 PF13863.1 EGO27675.1 - 2.5 8.0 9.2 0.17 11.8 1.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) GTP_cyclohydro2 PF00925.15 EGO27676.1 - 4.9e-63 211.3 0.0 3.9e-58 195.4 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Shisa PF13908.1 EGO27678.1 - 0.0021 18.2 0.1 0.0072 16.5 0.0 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EGO27678.1 - 0.014 13.6 0.1 0.018 13.3 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_M28 PF04389.12 EGO27680.1 - 5.1e-16 58.9 0.1 1.3e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EGO27680.1 - 2.8e-13 49.5 0.1 9e-12 44.6 0.0 2.4 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Nicastrin PF05450.10 EGO27680.1 - 0.053 12.7 0.4 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Nicastrin AA_permease_C PF13906.1 EGO27681.1 - 0.071 12.9 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 C-terminus of AA_permease NUDIX PF00293.23 EGO27682.1 - 7.6e-18 64.4 0.0 9.2e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Spermine_synth PF01564.12 EGO27683.1 - 8e-09 34.7 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase DIOX_N PF14226.1 EGO27684.1 - 4.1e-23 82.1 0.1 6.9e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO27684.1 - 1.4e-18 66.9 0.0 2.5e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RCC1 PF00415.13 EGO27685.1 - 5.7e-49 164.1 15.1 3.2e-09 36.8 0.1 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO27685.1 - 1.3e-32 110.6 42.7 4.2e-06 26.2 2.3 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Aldedh PF00171.17 EGO27686.1 - 5.4e-149 496.4 0.0 6.4e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO27686.1 - 0.0013 17.5 0.2 0.0031 16.3 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF4242 PF14026.1 EGO27686.1 - 0.069 13.2 0.0 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) Snf7 PF03357.16 EGO27687.1 - 1.9e-44 151.0 12.9 2.3e-44 150.7 8.9 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 EGO27687.1 - 0.0048 16.6 13.2 0.18 11.5 0.0 3.6 2 1 0 3 3 3 2 Prefoldin subunit DUF1569 PF07606.6 EGO27687.1 - 0.013 15.4 0.2 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) FlaC_arch PF05377.6 EGO27687.1 - 0.032 14.1 6.4 1.7 8.6 0.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Blo-t-5 PF11642.3 EGO27687.1 - 0.07 12.8 4.0 1.4 8.6 1.1 2.3 1 1 1 2 2 2 0 Mite allergen Blo t 5 DUF4559 PF15112.1 EGO27687.1 - 0.2 10.7 5.0 0.31 10.1 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Mnd1 PF03962.10 EGO27687.1 - 0.33 10.6 10.9 3.8 7.1 7.3 2.2 1 1 0 1 1 1 0 Mnd1 family NPV_P10 PF05531.7 EGO27687.1 - 0.67 10.2 4.2 4 7.7 0.3 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 EGO27687.1 - 1 9.2 14.0 0.36 10.7 7.2 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HeLo PF14479.1 EGO27687.1 - 1.5 8.5 6.9 0.26 11.0 0.8 2.0 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF4140 PF13600.1 EGO27687.1 - 5.7 7.4 7.3 7.4 7.0 0.2 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 EGO27687.1 - 9.6 4.4 11.6 1.4 7.2 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Abhydrolase_1 PF00561.15 EGO27690.1 - 9.4e-17 61.3 0.1 9.8e-15 54.7 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO27690.1 - 3.2e-10 40.2 1.8 1.2e-08 35.1 1.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGO27690.1 - 0.0016 17.9 0.2 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Neuropep_like PF15161.1 EGO27690.1 - 0.21 11.0 0.4 0.45 10.0 0.3 1.4 1 0 0 1 1 1 0 Neuropeptide-like Snf7 PF03357.16 EGO27691.1 - 2.5e-18 66.0 14.0 3.1e-18 65.7 9.7 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EGO27691.1 - 0.073 12.4 2.7 0.14 11.5 1.9 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway IMP_cyclohyd PF07826.6 EGO27691.1 - 0.078 12.3 0.3 0.098 11.9 0.2 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein SYCE1 PF15233.1 EGO27691.1 - 0.3 10.9 7.2 8.3 6.3 4.8 2.3 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Fib_alpha PF08702.5 EGO27691.1 - 8.3 6.5 7.0 4.5 7.3 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Erv26 PF04148.8 EGO27692.1 - 4.1e-57 192.9 13.0 5.1e-57 192.6 9.0 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Mtp PF03821.11 EGO27692.1 - 0.2 11.0 4.0 0.28 10.5 2.8 1.3 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter DUF2909 PF11137.3 EGO27692.1 - 0.24 11.1 4.8 0.058 13.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) MULE PF10551.4 EGO27694.1 - 0.027 14.6 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain DUF3527 PF12043.3 EGO27697.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) BUD22 PF09073.5 EGO27699.1 - 0.14 11.2 12.1 0.26 10.3 8.4 1.4 1 0 0 1 1 1 0 BUD22 YL1 PF05764.8 EGO27699.1 - 0.27 10.8 15.7 0.46 10.0 10.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EGO27699.1 - 0.44 8.5 12.3 0.59 8.1 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Syja_N PF02383.13 EGO27701.1 - 2.7e-75 253.0 0.0 3.6e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EGO27701.1 - 3e-25 89.6 0.2 4.7e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SF3a60_bindingd PF12108.3 EGO27702.1 - 6.6e-06 25.5 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Type_III_YscX PF09474.5 EGO27702.1 - 0.025 14.6 1.1 0.029 14.3 0.7 1.1 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) DUF3035 PF11233.3 EGO27702.1 - 0.073 13.1 0.4 0.088 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF4254 PF14063.1 EGO27702.1 - 0.12 11.9 2.1 0.2 11.2 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) DEAD PF00270.24 EGO27703.1 - 8.6e-42 142.4 0.1 1.6e-41 141.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO27703.1 - 2.9e-27 94.3 0.2 7e-27 93.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGO27703.1 - 0.0042 16.8 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EGO27703.1 - 0.013 15.3 0.0 0.043 13.6 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO27703.1 - 0.017 15.2 0.2 0.07 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGO27703.1 - 0.041 13.4 0.7 0.09 12.3 0.2 1.8 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 EGO27703.1 - 0.07 12.4 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RRM_1 PF00076.17 EGO27706.1 - 1.4e-18 66.2 0.1 2.5e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27706.1 - 8.4e-15 54.5 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27706.1 - 4.4e-10 39.2 1.1 5.2e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO27706.1 - 0.036 13.9 0.2 0.086 12.6 0.2 1.6 1 1 0 1 1 1 0 RNA binding motif DUF2076 PF09849.4 EGO27707.1 - 0.038 14.0 0.3 0.047 13.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Connexin_CCC PF10582.4 EGO27707.1 - 6.5 6.6 8.1 4e+02 0.8 5.6 2.4 1 1 0 1 1 1 0 Gap junction channel protein cysteine-rich domain Aldedh PF00171.17 EGO27709.1 - 3.6e-154 513.5 0.7 4.2e-154 513.3 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4605 PF15378.1 EGO27710.1 - 0.17 11.6 2.6 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) NOA36 PF06524.7 EGO27713.1 - 8.9 5.4 10.8 12 5.0 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein BTG PF07742.7 EGO27717.1 - 4.1e-11 42.4 0.0 6.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 BTG family WD40 PF00400.27 EGO27718.1 - 5.6e-16 57.7 9.2 0.0038 17.0 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EGO27718.1 - 5.5e-05 22.9 0.0 0.31 10.7 0.0 2.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGO27718.1 - 0.0018 17.9 0.0 0.59 9.8 0.0 3.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EGO27718.1 - 0.011 13.6 0.1 0.19 9.5 0.0 2.2 2 1 0 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.11 EGO27718.1 - 0.034 12.4 0.1 0.097 10.9 0.0 1.7 2 1 0 2 2 2 0 Cytochrome D1 heme domain Abhydrolase_6 PF12697.2 EGO27719.1 - 5.3e-23 82.1 0.1 5.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO27719.1 - 7.1e-15 55.1 0.0 9.5e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO27719.1 - 1.7e-09 37.6 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EGO27719.1 - 4.1e-08 32.0 0.0 5.5e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family TFIIB PF00382.14 EGO27722.1 - 3.6e-37 126.0 0.0 1.7e-21 75.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGO27722.1 - 8.1e-14 50.6 1.4 1.4e-13 49.9 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.15 EGO27722.1 - 0.0012 18.4 0.0 3.2 7.4 0.0 3.0 3 0 0 3 3 3 2 Bacterial regulatory protein, arsR family HTH_23 PF13384.1 EGO27722.1 - 0.0099 15.5 0.0 2.9 7.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain Cyclin_C PF02984.14 EGO27722.1 - 0.011 15.6 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain HTH_28 PF13518.1 EGO27722.1 - 0.049 13.6 0.0 17 5.5 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain Cyclin_N PF00134.18 EGO27722.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain UNC45-central PF11701.3 EGO27722.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central HTH_24 PF13412.1 EGO27722.1 - 0.13 11.7 0.0 9.4 5.7 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RRS1 PF04939.7 EGO27723.1 - 3.8e-09 36.2 0.0 4.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TIP41 PF04176.8 EGO27724.1 - 1.8e-52 177.2 0.0 2.4e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.6 EGO27725.1 - 4e-35 121.3 6.8 1e-26 93.6 0.0 4.1 4 1 0 4 4 4 3 Dynein light intermediate chain (DLIC) KTI12 PF08433.5 EGO27725.1 - 0.03 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 EGO27725.1 - 0.062 13.2 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGO27725.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FANCI_S1-cap PF14674.1 EGO27725.1 - 0.52 10.3 1.6 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 1 cap Hep_59 PF07052.6 EGO27727.1 - 4e-26 91.3 1.7 4e-26 91.3 1.2 2.8 2 1 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Pro-kuma_activ PF09286.6 EGO27729.1 - 1.1e-36 126.0 0.1 2.6e-36 124.7 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO27729.1 - 3.1e-09 36.3 0.7 9.1e-09 34.8 0.2 1.9 1 1 1 2 2 2 1 Subtilase family PCI PF01399.22 EGO27730.1 - 1.4e-14 54.2 0.1 6.9e-14 52.0 0.0 2.2 2 1 0 2 2 2 1 PCI domain ASD2 PF08687.6 EGO27730.1 - 0.65 9.2 3.3 0.53 9.5 0.3 2.2 3 0 0 3 3 3 0 Apx/Shroom domain ASD2 DUF2009 PF09418.5 EGO27731.1 - 2.3e-204 679.4 0.0 2.7e-204 679.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EGO27731.1 - 1.9e-06 27.6 6.2 3.6e-06 26.7 4.3 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-HIT PF04438.11 EGO27731.1 - 0.026 14.1 3.3 0.053 13.1 2.3 1.5 1 0 0 1 1 1 0 HIT zinc finger IBR PF01485.16 EGO27731.1 - 0.12 12.2 6.3 0.3 11.0 4.4 1.6 1 0 0 1 1 1 0 IBR domain DUF3661 PF12400.3 EGO27732.1 - 4.8e-36 123.6 3.2 7.1e-36 123.1 2.2 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein AAA PF00004.24 EGO27733.1 - 2e-53 180.1 0.0 8.6e-40 135.9 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO27733.1 - 4.8e-11 42.9 0.6 0.00022 21.3 0.2 4.3 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EGO27733.1 - 3.3e-09 37.0 0.3 0.0012 18.8 0.0 3.2 2 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 EGO27733.1 - 7.2e-09 35.7 0.0 7e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGO27733.1 - 2.6e-08 33.8 0.0 0.0049 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGO27733.1 - 3.3e-08 34.3 0.0 0.001 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGO27733.1 - 5.8e-08 32.5 0.3 0.0013 18.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGO27733.1 - 1.3e-07 31.2 1.6 0.0062 16.2 0.1 2.9 3 0 0 3 3 2 2 Part of AAA domain RuvB_N PF05496.7 EGO27733.1 - 2e-07 30.2 0.1 0.017 14.1 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGO27733.1 - 2.1e-07 31.3 0.2 0.0029 17.8 0.1 2.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGO27733.1 - 5.7e-07 28.5 0.0 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EGO27733.1 - 1.4e-06 27.6 0.3 0.0056 15.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGO27733.1 - 1.6e-06 28.4 0.0 0.032 14.5 0.1 2.9 2 1 0 2 2 2 2 ABC transporter AAA_14 PF13173.1 EGO27733.1 - 1.6e-06 28.0 0.0 0.048 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EGO27733.1 - 4.9e-06 26.2 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGO27733.1 - 1.4e-05 24.2 0.1 0.09 11.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EGO27733.1 - 2.4e-05 24.4 0.0 0.091 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EGO27733.1 - 2.7e-05 23.6 3.3 0.65 9.3 0.0 4.2 2 2 1 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EGO27733.1 - 3.2e-05 23.4 1.3 0.022 14.1 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein NACHT PF05729.7 EGO27733.1 - 4.5e-05 23.1 2.4 0.26 10.9 0.1 3.4 4 0 0 4 4 4 2 NACHT domain Sigma54_activat PF00158.21 EGO27733.1 - 8.2e-05 22.1 0.0 0.31 10.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 EGO27733.1 - 0.00012 21.6 0.0 0.077 12.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGO27733.1 - 0.00014 21.1 0.2 0.018 14.1 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.1 EGO27733.1 - 0.0002 21.3 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EGO27733.1 - 0.00041 19.6 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.1 EGO27733.1 - 0.00043 19.9 0.0 0.76 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EGO27733.1 - 0.00051 19.1 0.1 0.13 11.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EGO27733.1 - 0.00095 18.8 1.2 0.99 8.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EGO27733.1 - 0.0012 18.5 0.1 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 CDC48_2 PF02933.12 EGO27733.1 - 0.0012 18.4 0.1 0.04 13.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 T2SE PF00437.15 EGO27733.1 - 0.0013 17.6 0.0 0.74 8.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 EGO27733.1 - 0.0025 16.6 0.1 0.39 9.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.10 EGO27733.1 - 0.0033 17.2 0.2 3.6 7.3 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EGO27733.1 - 0.0034 17.0 0.5 20 4.7 0.0 3.6 2 2 1 3 3 3 0 Archaeal ATPase CPT PF07931.7 EGO27733.1 - 0.0059 16.2 0.1 0.49 9.9 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EGO27733.1 - 0.013 14.7 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Torsin PF06309.6 EGO27733.1 - 0.014 15.2 0.0 7.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.12 EGO27733.1 - 0.018 13.9 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SKI PF01202.17 EGO27733.1 - 0.019 14.8 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase cobW PF02492.14 EGO27733.1 - 0.023 14.1 0.3 4 6.8 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EGO27733.1 - 0.024 14.1 0.0 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.11 EGO27733.1 - 0.06 12.1 0.0 5.5 5.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase KAP_NTPase PF07693.9 EGO27733.1 - 0.06 12.3 0.2 9.8 5.0 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.10 EGO27733.1 - 0.071 12.8 0.6 10 5.8 0.0 3.0 3 0 0 3 3 3 0 NTPase FUSC PF04632.7 EGO27733.1 - 0.08 11.3 0.3 0.11 10.8 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DAP3 PF10236.4 EGO27733.1 - 0.15 10.9 0.0 15 4.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zot PF05707.7 EGO27733.1 - 0.2 11.0 0.2 15 5.0 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.4 EGO27733.1 - 0.23 10.0 0.4 2.4 6.7 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IPP-2 PF04979.9 EGO27734.1 - 2.3e-13 50.5 2.2 1.1e-06 28.9 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) THF_DHG_CYH PF00763.18 EGO27735.1 - 1.5e-17 63.6 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EGO27735.1 - 2.6e-17 62.3 0.5 9.4e-10 37.7 0.0 2.8 1 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EGO27735.1 - 0.0045 17.0 0.1 0.33 11.0 0.0 2.3 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF927 PF06048.6 EGO27735.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) DUF2404 PF10296.4 EGO27738.1 - 1.8e-05 24.8 0.1 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PLU-1 PF08429.6 EGO27739.1 - 2e-52 178.1 0.4 2e-52 178.1 0.3 2.2 2 1 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EGO27739.1 - 4.3e-42 142.9 1.6 7.9e-42 142.1 0.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EGO27739.1 - 1e-20 73.3 0.0 3.6e-20 71.6 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EGO27739.1 - 1.2e-14 53.6 39.5 2.2e-11 43.2 6.2 4.5 4 0 0 4 4 4 2 PHD-finger JmjN PF02375.12 EGO27739.1 - 2.5e-14 52.4 0.2 6.1e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EGO27739.1 - 2.7e-12 46.5 9.4 2.7e-12 46.5 6.5 2.2 2 0 0 2 2 2 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 EGO27739.1 - 0.019 14.7 27.1 0.033 13.9 4.6 3.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EGO27739.1 - 0.2 10.9 18.3 0.52 9.6 1.1 3.9 3 0 0 3 3 3 0 PHD-finger CorA PF01544.13 EGO27740.1 - 4.6e-47 160.4 0.6 6.1e-47 160.0 0.4 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3826 PF12875.2 EGO27740.1 - 0.003 17.2 0.4 0.072 12.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3826) Baculo_PEP_C PF04513.7 EGO27740.1 - 0.0041 16.9 0.3 0.0092 15.8 0.1 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3561 PF12084.3 EGO27743.1 - 0.13 12.1 2.6 0.18 11.6 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) PGAP1 PF07819.8 EGO27744.1 - 3.1e-54 183.9 0.0 4e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGO27744.1 - 5.7e-10 39.1 0.0 8.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO27744.1 - 5.7e-08 32.9 0.4 7.4e-08 32.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EGO27744.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EGO27744.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 EGO27744.1 - 0.034 13.2 0.0 0.73 8.8 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) 14-3-3 PF00244.15 EGO27746.1 - 5.4e-118 392.2 5.7 6.3e-118 392.0 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EGO27746.1 - 0.055 13.0 4.3 1.6 8.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) HisKA PF00512.20 EGO27746.1 - 0.07 13.1 1.4 2.4 8.2 0.1 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF885 PF05960.6 EGO27746.1 - 0.29 10.2 3.9 0.082 12.0 0.9 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) CLPTM1 PF05602.7 EGO27748.1 - 7e-123 410.5 0.1 1.2e-122 409.7 0.1 1.3 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EGO27748.1 - 0.00044 19.7 0.4 0.0011 18.4 0.3 1.7 1 0 0 1 1 1 1 PQ loop repeat MA3 PF02847.12 EGO27749.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 MA3 domain MoCF_biosynth PF00994.19 EGO27750.1 - 1.4e-61 206.1 0.4 5.8e-30 103.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EGO27750.1 - 1.9e-30 105.3 0.1 4.9e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGO27750.1 - 1.6e-12 47.1 0.3 4.1e-12 45.8 0.1 1.8 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 EGO27750.1 - 7.6 5.8 13.6 12 5.2 9.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S10 PF00450.17 EGO27752.1 - 9.6e-98 328.0 0.0 1.2e-97 327.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_gE PF02480.11 EGO27752.1 - 0.003 15.8 0.0 0.0044 15.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E stn_TNFRSF12A PF12191.3 EGO27752.1 - 0.04 13.9 0.1 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PgaD PF13994.1 EGO27752.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Ldr_toxin PF13940.1 EGO27753.1 - 0.033 13.9 0.1 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system Ribosomal_L13 PF00572.13 EGO27754.1 - 2.9e-45 153.4 0.5 3.7e-45 153.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Tankyrase_bdg_C PF15327.1 EGO27755.1 - 0.52 10.4 15.4 0.022 14.9 2.6 2.6 2 1 1 3 3 3 0 Tankyrase binding protein C terminal domain SMC_N PF02463.14 EGO27756.1 - 7.5e-20 71.1 0.0 2e-19 69.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO27756.1 - 1.7e-18 67.7 0.0 1.7e-18 67.7 0.0 4.7 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EGO27756.1 - 0.0016 17.8 0.1 0.02 14.4 0.0 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGO27756.1 - 0.0068 16.3 0.1 0.0068 16.3 0.1 3.1 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EGO27756.1 - 0.0097 15.3 0.0 0.05 13.0 0.0 2.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.24 EGO27756.1 - 0.068 13.3 2.9 1.1 9.4 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Semialdhyde_dh PF01118.19 EGO27757.1 - 4.9e-19 68.8 0.0 5.4e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGO27757.1 - 0.0084 16.0 0.0 0.0096 15.8 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EGO27757.1 - 0.02 15.4 0.0 0.022 15.3 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.18 EGO27757.1 - 0.068 13.0 0.0 0.087 12.6 0.0 1.3 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Rab5ip PF07019.7 EGO27758.1 - 2.7e-14 53.0 5.2 3.6e-14 52.6 3.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_11 PF13414.1 EGO27760.1 - 6.9e-16 57.6 1.4 5e-08 32.4 0.0 4.9 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGO27760.1 - 3.5e-12 45.2 6.5 0.00026 20.6 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO27760.1 - 3.1e-11 42.3 0.0 0.0026 17.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO27760.1 - 1.1e-09 38.1 0.1 0.018 14.9 0.0 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO27760.1 - 3.6e-08 33.8 6.5 9.9e-07 29.2 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO27760.1 - 2.7e-07 30.6 7.5 0.027 15.0 0.0 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO27760.1 - 2.3e-06 27.3 0.1 0.16 12.2 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO27760.1 - 5.5e-05 22.6 0.0 0.093 12.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO27760.1 - 0.00017 21.1 4.9 1.3 8.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO27760.1 - 0.0015 18.3 0.0 0.012 15.4 0.0 2.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO27760.1 - 0.0061 16.9 0.0 1.8 9.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO27760.1 - 0.0089 16.3 0.0 3.7 7.9 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO27760.1 - 0.016 15.1 8.0 0.14 12.1 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.4 EGO27760.1 - 0.069 12.5 0.2 3.4 6.9 0.0 3.6 5 0 0 5 5 5 0 26S proteasome subunit RPN7 4HBT PF03061.17 EGO27761.1 - 4.5e-07 29.9 0.1 7.3e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.17 EGO27762.1 - 0.1 12.7 0.1 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Ham1p_like PF01725.11 EGO27763.1 - 7.3e-53 178.7 0.0 8.3e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RNA_pol_Rpb1_5 PF04998.12 EGO27765.1 - 1.5e-85 286.8 0.0 2.7e-85 286.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGO27765.1 - 1.6e-48 164.8 0.1 3.2e-48 163.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGO27765.1 - 5e-37 127.0 0.0 1.3e-36 125.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EGO27765.1 - 7.4e-30 104.3 0.4 3.1e-23 82.5 0.0 3.3 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EGO27765.1 - 7.7e-21 73.8 0.0 2.3e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_I_TF PF04090.7 EGO27767.1 - 1.8e-11 43.7 0.9 3.7e-08 32.8 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_11 PF13414.1 EGO27767.1 - 0.0018 17.9 1.2 0.32 10.6 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_19 PF14559.1 EGO27767.1 - 0.0024 18.1 1.6 1.6 9.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO27767.1 - 0.14 12.8 3.1 7.1 7.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO27767.1 - 0.16 11.9 0.8 2.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RIX1 PF08167.7 EGO27768.1 - 6.5e-24 84.4 4.0 6.5e-24 84.4 2.8 2.7 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec10 PF07393.6 EGO27769.1 - 2.4e-224 746.6 0.0 3.2e-224 746.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Filament PF00038.16 EGO27769.1 - 0.29 10.5 3.7 0.94 8.8 1.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein ECH PF00378.15 EGO27770.1 - 3.3e-57 193.4 0.0 4.1e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RicinB_lectin_2 PF14200.1 EGO27773.1 - 2.3e-08 34.3 5.6 4.3e-07 30.2 0.8 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like LMWSLP_N PF12211.3 EGO27773.1 - 0.024 14.5 3.0 0.12 12.2 0.6 1.9 1 1 1 2 2 2 0 Low molecular weight S layer protein N terminal RicinB_lectin_2 PF14200.1 EGO27774.1 - 1.2e-11 44.9 7.2 9.9e-08 32.3 0.3 3.3 1 1 2 4 4 4 2 Ricin-type beta-trefoil lectin domain-like LMWSLP_N PF12211.3 EGO27774.1 - 0.00061 19.7 5.2 0.068 12.9 0.1 2.4 1 1 0 2 2 2 2 Low molecular weight S layer protein N terminal GPI-anchored PF10342.4 EGO27774.1 - 0.038 14.4 12.2 4.5 7.8 2.4 4.4 2 1 1 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Polyketide_cyc2 PF10604.4 EGO27774.1 - 0.12 12.5 0.1 0.77 9.9 0.0 2.3 2 1 1 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport Med15 PF09606.5 EGO27775.1 - 0.13 10.4 29.9 0.16 10.1 20.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EGO27775.1 - 0.79 7.8 23.5 0.88 7.7 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_Tnp_4 PF13359.1 EGO27776.1 - 1.6e-21 76.5 0.0 2.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EGO27780.1 - 0.0031 17.3 4.4 0.0048 16.7 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO27780.1 - 0.02 14.9 0.1 0.058 13.4 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4219 PF13961.1 EGO27782.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Retrotrans_gag PF03732.12 EGO27785.1 - 2.5e-08 33.8 0.2 2.5e-08 33.8 0.2 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein BMFP PF04380.8 EGO27785.1 - 0.04 14.0 1.2 19 5.4 0.2 3.5 3 0 0 3 3 3 0 Membrane fusogenic activity zf-CCHC PF00098.18 EGO27786.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO27786.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO27786.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.24 EGO27787.1 - 0.00055 19.4 0.1 0.00066 19.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO27787.1 - 0.013 15.2 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit QRPTase_C PF01729.14 EGO27788.1 - 6.2e-48 162.5 0.1 7.7e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGO27788.1 - 9.4e-22 76.6 0.0 2.9e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SIP1 PF04938.7 EGO27789.1 - 1.3e-16 60.6 0.0 2.6e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DSPc PF00782.15 EGO27793.1 - 3e-32 110.9 0.0 3.5e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO27793.1 - 2.6e-05 23.6 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EGO27793.1 - 0.092 11.4 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain GBP_repeat PF02526.9 EGO27794.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycophorin-binding protein Sec15 PF04091.7 EGO27795.1 - 8.6e-76 255.2 0.7 4.6e-75 252.8 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 EGO27795.1 - 6.2e-07 29.4 0.7 6.2e-07 29.4 0.5 3.2 3 1 1 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EGO27795.1 - 1.7e-05 24.5 0.5 1.7e-05 24.5 0.4 2.8 3 0 0 3 3 3 1 Vps51/Vps67 Sec8_exocyst PF04048.9 EGO27795.1 - 5.9e-05 22.7 1.1 0.00027 20.5 0.7 2.2 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 EGO27795.1 - 0.00014 21.6 0.7 0.00046 19.9 0.1 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.6 EGO27795.1 - 0.0058 16.4 1.6 0.0058 16.4 1.1 3.2 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 EGO27795.1 - 0.051 13.4 0.2 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cortex-I_coil PF09304.5 EGO27795.1 - 0.079 13.0 2.1 5.7 7.0 0.5 3.3 2 1 0 2 2 2 0 Cortexillin I, coiled coil HsbA PF12296.3 EGO27795.1 - 0.11 12.2 4.6 0.19 11.6 0.1 2.9 3 0 0 3 3 3 0 Hydrophobic surface binding protein A HAD_2 PF13419.1 EGO27796.1 - 1.3e-16 61.2 0.0 1.9e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO27796.1 - 3.5e-12 47.1 0.2 1.1e-10 42.3 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO27796.1 - 2.3e-10 40.0 0.0 5.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGO27796.1 - 0.0067 16.6 0.1 0.032 14.4 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tubulin PF00091.20 EGO27797.1 - 1.3e-67 227.7 0.0 1.8e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO27797.1 - 2.8e-46 156.6 0.0 4.1e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGO27797.1 - 0.00068 19.1 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EGO27797.1 - 0.0039 16.8 0.0 0.99 9.0 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Tubulin PF00091.20 EGO27798.1 - 3.7e-60 203.4 0.0 6.6e-60 202.6 0.0 1.4 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO27798.1 - 8.7e-48 161.5 0.0 1.4e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGO27798.1 - 0.00057 19.3 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EGO27798.1 - 0.025 14.1 0.0 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EGO27799.1 - 1.5e-32 112.9 0.5 5.2e-23 81.7 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO27799.1 - 6.5e-10 38.2 0.0 1.1e-08 34.1 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO27799.1 - 0.00038 20.2 0.0 0.00097 18.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family CPSF100_C PF13299.1 EGO27800.1 - 3.8e-28 98.6 0.0 3.8e-28 98.6 0.0 3.7 4 1 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EGO27800.1 - 2.7e-19 69.3 0.0 6.7e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EGO27800.1 - 5.2e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain tRNA-synt_1c PF00749.16 EGO27801.1 - 2.6e-106 354.8 0.0 3.5e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGO27801.1 - 6.5e-31 107.3 0.0 1.5e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EGO27801.1 - 1.6e-28 99.2 0.0 2.6e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EGO27801.1 - 6.3e-07 29.9 3.5 2.2e-06 28.2 2.4 2.0 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PAF-AH_p_II PF03403.8 EGO27802.1 - 2.1e-41 141.4 0.0 4.3e-41 140.4 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGO27802.1 - 1.6e-10 40.8 0.0 5.7e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGO27802.1 - 9.4e-06 24.6 0.0 0.036 12.9 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EGO27802.1 - 3.1e-05 23.9 0.2 9.3e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EGO27802.1 - 0.0011 17.8 0.0 0.34 9.6 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.3 EGO27802.1 - 0.0033 17.2 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EGO27802.1 - 0.14 12.3 0.2 20 5.3 0.0 2.4 2 1 0 2 2 2 0 Thioesterase domain DUF2985 PF11204.3 EGO27803.1 - 1e-26 92.4 3.1 6.1e-26 90.0 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Meth_synt_2 PF01717.13 EGO27804.1 - 1.7e-139 464.3 0.0 8.9e-136 452.1 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGO27804.1 - 8.9e-121 402.9 0.0 8.3e-109 363.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Rsd_AlgQ PF04353.8 EGO27804.1 - 0.0085 15.8 0.1 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Pkinase PF00069.20 EGO27805.1 - 9.3e-52 175.7 0.0 1.2e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27805.1 - 2e-25 89.3 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGO27805.1 - 0.25 10.0 0.4 0.41 9.3 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase ADH_N PF08240.7 EGO27806.1 - 5.3e-31 106.5 0.3 8.5e-31 105.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO27806.1 - 5.8e-25 87.3 0.3 9.4e-25 86.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO27806.1 - 4.9e-07 30.6 0.1 9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGO27806.1 - 0.0028 18.1 0.1 0.006 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO27806.1 - 0.0095 15.0 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.9 EGO27806.1 - 0.014 14.7 0.0 0.074 12.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EGO27806.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EGO27806.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGO27806.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.22 EGO27808.1 - 1.6e-49 167.8 0.0 2.5e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGO27808.1 - 1.2e-15 57.1 0.0 5.1e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.1 EGO27808.1 - 2.4e-14 52.9 0.0 5.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGO27808.1 - 1.1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO27808.1 - 0.00097 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGO27808.1 - 0.11 11.6 0.0 0.36 10.0 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ICMT PF04140.9 EGO27809.1 - 1.2e-27 95.9 0.3 2.7e-27 94.7 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO27809.1 - 1.2e-13 51.0 1.1 1.2e-13 51.0 0.7 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EGO27809.1 - 0.00023 19.8 0.4 0.00037 19.1 0.3 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3593 PF12159.3 EGO27809.1 - 3.1 7.6 5.0 1.2 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Ribosomal_L6 PF00347.18 EGO27810.1 - 1.5e-29 102.3 7.1 1.3e-15 57.6 1.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CTD_bind PF04818.8 EGO27811.1 - 0.0021 18.2 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EGO27811.1 - 0.04 14.0 0.2 0.24 11.5 0.0 2.3 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 PIN_4 PF13638.1 EGO27812.1 - 1.8e-21 76.6 0.0 2.9e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 PIN domain MFS_1 PF07690.11 EGO27813.1 - 1.3e-33 116.1 21.4 8.4e-33 113.5 8.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO27813.1 - 1.8e-11 43.3 0.4 1.8e-11 43.3 0.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 EGO27813.1 - 0.00056 18.7 0.4 0.001 17.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 EGO27813.1 - 0.0013 17.2 11.8 0.037 12.4 0.1 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein TruD PF01142.13 EGO27814.1 - 1.5e-64 218.0 0.0 1.1e-63 215.2 0.0 2.3 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) OMPdecase PF00215.19 EGO27815.1 - 1.2e-70 237.4 0.0 1.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family eRF1_1 PF03463.10 EGO27816.1 - 1e-42 144.8 0.0 1.8e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EGO27816.1 - 5.8e-23 81.3 0.0 1.2e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EGO27816.1 - 2.3e-17 63.5 0.0 3.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Phosducin PF02114.11 EGO27817.1 - 0.015 14.0 0.1 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin PF00085.15 EGO27817.1 - 0.033 13.8 0.1 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin FAD_binding_7 PF03441.9 EGO27818.1 - 3.8e-88 295.2 0.1 6e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGO27818.1 - 2e-33 115.4 0.0 3.9e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF1793 PF08760.6 EGO27819.1 - 2.5e-64 216.2 1.4 2.5e-64 216.2 0.9 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) BicD PF09730.4 EGO27821.1 - 0.031 12.6 4.4 0.048 12.0 3.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D UBN2_2 PF14227.1 EGO27821.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Nucleo_P87 PF07267.6 EGO27821.1 - 3 6.4 9.0 3.6 6.1 6.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_18 PF00704.23 EGO27823.1 - 5.3e-57 193.8 0.2 6e-57 193.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3198 PF11433.3 EGO27825.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) MFS_2 PF13347.1 EGO27826.1 - 4.1e-10 38.6 5.5 4.1e-10 38.6 3.8 2.4 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.11 EGO27826.1 - 1.3e-09 37.2 22.4 8.7e-08 31.2 15.6 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Reticulon PF02453.12 EGO27826.1 - 2.2 7.8 10.9 0.26 10.8 0.1 3.0 3 0 0 3 3 3 0 Reticulon ATP_bind_4 PF01902.12 EGO27827.1 - 3.1e-41 141.1 0.0 3.6e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 ATP-binding region B3_4 PF03483.12 EGO27828.1 - 3.4e-26 91.7 0.1 5.9e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGO27828.1 - 2.1e-16 59.5 0.0 5.4e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EGO27828.1 - 0.0064 15.7 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF2370 PF10176.4 EGO27829.1 - 2.1e-67 226.8 1.0 3.9e-67 226.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF4425 PF14466.1 EGO27833.1 - 0.051 13.6 0.0 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4425) Ribonuclease PF00545.15 EGO27835.1 - 1.3e-09 38.0 0.1 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Acetyltransf_1 PF00583.19 EGO27836.1 - 7.2e-13 48.3 0.4 1.2e-12 47.6 0.3 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO27836.1 - 4.2e-08 32.8 0.0 8.3e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO27836.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO27836.1 - 5.6e-07 29.6 0.0 1.2e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO27836.1 - 1.9e-05 24.8 0.0 0.0011 19.1 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO27836.1 - 0.0004 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGO27836.1 - 0.00071 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO27836.1 - 0.0092 15.9 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGO27836.1 - 0.014 14.6 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 MOZ/SAS family Acetyltransf_8 PF13523.1 EGO27836.1 - 0.018 14.9 0.0 0.047 13.5 0.0 1.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Retrotrans_gag PF03732.12 EGO27837.1 - 0.0069 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 EGO27838.1 - 6.7e-07 29.3 0.0 8.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO27838.1 - 2.1e-06 27.4 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO27838.1 - 3.2e-05 24.3 0.0 5.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Ribonuclease PF00545.15 EGO27839.1 - 1.4e-09 37.9 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Acetyltransf_1 PF00583.19 EGO27840.1 - 7.3e-13 48.3 0.4 1.2e-12 47.6 0.3 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO27840.1 - 3.1e-08 33.2 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO27840.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO27840.1 - 5.6e-07 29.6 0.0 1.2e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO27840.1 - 1.9e-05 24.8 0.0 0.0011 19.1 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO27840.1 - 0.00039 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGO27840.1 - 0.00071 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO27840.1 - 0.0066 16.4 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGO27840.1 - 0.014 14.6 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 MOZ/SAS family Acetyltransf_8 PF13523.1 EGO27840.1 - 0.016 15.0 0.1 0.043 13.6 0.0 1.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF1212 PF06738.7 EGO27841.1 - 1.1e-33 116.2 3.1 1.1e-33 116.2 2.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGO27841.1 - 1e-14 54.5 8.4 1e-14 54.5 5.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) tRNA-synt_2d PF01409.15 EGO27842.1 - 3.1e-85 285.2 0.0 3.3e-84 281.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGO27842.1 - 4.8e-05 23.0 0.2 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EGO27842.1 - 0.00034 19.4 1.7 0.002 16.9 0.1 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Pex2_Pex12 PF04757.9 EGO27843.1 - 4.2e-35 121.2 9.6 5.8e-35 120.7 6.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 EGO27843.1 - 0.00013 21.6 4.5 0.00018 21.1 1.5 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO27843.1 - 0.00086 19.0 3.2 0.0058 16.4 0.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGO27843.1 - 0.0012 18.8 1.3 0.0074 16.3 0.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGO27843.1 - 0.005 16.8 3.5 0.005 16.8 2.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RDD PF06271.7 EGO27843.1 - 0.0054 16.6 0.1 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RDD family zf-C3HC4 PF00097.20 EGO27843.1 - 0.0064 16.1 3.4 0.065 12.9 2.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO27843.1 - 0.0083 15.9 2.6 0.026 14.3 1.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO27843.1 - 0.029 14.0 0.3 0.081 12.6 0.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-4CXXC_R1 PF10497.4 EGO27843.1 - 0.046 13.8 0.3 0.077 13.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE PF01363.16 EGO27843.1 - 0.96 9.3 3.2 0.98 9.3 0.6 2.0 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_3 PF13920.1 EGO27843.1 - 1.1 8.9 6.0 2.5 7.8 1.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3658 PF12395.3 EGO27844.1 - 0.0031 17.0 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function Mur_ligase_M PF08245.7 EGO27845.1 - 5.9e-08 32.9 0.0 2.4e-06 27.7 0.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain PBP1_TM PF14812.1 EGO27847.1 - 0.0096 16.2 1.0 0.023 14.9 0.7 1.7 1 1 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex14_N PF04695.8 EGO27847.1 - 0.12 12.3 0.1 4.5 7.3 0.0 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Vps52 PF04129.7 EGO27851.1 - 3.9e-38 131.2 0.0 4.7e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EGO27851.1 - 4.4e-06 25.1 1.4 1.6e-05 23.2 0.2 1.9 1 1 1 2 2 2 1 Exocyst complex component Sec3 MscS_porin PF12795.2 EGO27851.1 - 0.0062 15.8 1.7 0.0064 15.8 0.4 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Cep57_MT_bd PF06657.8 EGO27851.1 - 0.054 13.4 1.1 0.054 13.4 0.8 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PrkA PF06798.7 EGO27851.1 - 0.1 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain COG2 PF06148.6 EGO27851.1 - 0.11 12.3 0.9 0.27 11.1 0.6 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Aldose_epim PF01263.15 EGO27853.1 - 5.1e-55 186.7 0.6 6.5e-55 186.3 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Radical_SAM_N PF08497.5 EGO27854.1 - 0.15 10.9 2.6 4.7 6.0 0.1 3.3 3 1 1 4 4 4 0 Radical SAM N-terminal JAB PF01398.16 EGO27855.1 - 2.1e-34 117.6 0.3 4e-34 116.7 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGO27855.1 - 1e-28 99.6 3.1 2.5e-28 98.4 2.2 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGO27855.1 - 9.9e-08 31.5 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EGO27855.1 - 0.067 12.6 0.7 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.15 EGO27856.1 - 4.2e-15 55.3 1.1 6.2e-15 54.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.20 EGO27857.1 - 6.5e-61 205.7 0.0 1.8e-40 138.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27857.1 - 5.5e-27 94.4 0.0 5.4e-23 81.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EGO27857.1 - 5.2e-12 45.7 0.1 1.1e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EGO27857.1 - 1.6e-07 30.5 0.1 4.5e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EGO27857.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO27857.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO27857.1 - 0.025 13.9 1.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 EGO27857.1 - 0.036 12.9 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pex14_N PF04695.8 EGO27858.1 - 0.097 12.7 0.4 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region THOC7 PF05615.8 EGO27860.1 - 8.2e-24 84.4 3.3 1.5e-23 83.5 2.3 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 Filament PF00038.16 EGO27860.1 - 0.0027 17.2 7.4 0.0045 16.5 5.1 1.3 1 0 0 1 1 1 1 Intermediate filament protein DUF842 PF05811.8 EGO27860.1 - 0.0054 16.1 1.8 0.025 14.0 0.2 2.2 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF842) WXG100 PF06013.7 EGO27860.1 - 0.028 14.4 1.2 1.5 8.9 0.1 2.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF342 PF03961.8 EGO27860.1 - 0.083 11.2 3.3 0.14 10.5 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4515 PF14988.1 EGO27860.1 - 0.17 11.4 9.7 0.3 10.7 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF4140 PF13600.1 EGO27860.1 - 1.5 9.3 9.7 7 7.1 1.1 2.8 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EGO27860.1 - 2.8 6.9 7.5 5.7 5.8 5.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EGO27860.1 - 3.8 7.0 7.5 10 5.6 1.1 2.3 1 1 1 2 2 2 0 Septum formation initiator OmpH PF03938.9 EGO27860.1 - 4 7.3 7.4 7.4 6.4 5.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 EGO27860.1 - 4.6 7.0 7.2 1.8 8.3 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Lactamase_B_2 PF12706.2 EGO27861.1 - 3.4e-24 85.4 0.0 5.2e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO27861.1 - 1.8e-10 40.7 0.1 3.5e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EGO27861.1 - 3.4e-06 26.4 0.0 6.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 EGO27861.1 - 0.052 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PSII_Pbs27 PF13326.1 EGO27861.1 - 0.081 12.9 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF2344 PF10105.4 EGO27862.1 - 0.016 14.7 0.5 0.027 13.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DivIC PF04977.10 EGO27862.1 - 0.023 14.1 0.3 0.023 14.1 0.2 2.5 1 1 1 2 2 2 0 Septum formation initiator Fmp27_WPPW PF10359.4 EGO27862.1 - 0.033 12.5 5.5 0.041 12.3 3.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIVA PF05103.8 EGO27862.1 - 0.06 13.3 2.9 0.27 11.3 2.0 2.1 1 1 0 1 1 1 0 DivIVA protein DMPK_coil PF08826.5 EGO27862.1 - 0.22 11.4 5.0 0.22 11.4 1.2 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like Laminin_II PF06009.7 EGO27862.1 - 0.28 10.9 3.9 0.51 10.1 2.7 1.4 1 0 0 1 1 1 0 Laminin Domain II Baculo_PEP_C PF04513.7 EGO27862.1 - 0.31 10.8 2.5 0.7 9.7 1.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Adaptin_binding PF10199.4 EGO27862.1 - 0.42 10.8 8.6 0.16 12.2 4.1 1.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 IncA PF04156.9 EGO27862.1 - 0.49 9.9 14.6 0.84 9.2 9.7 1.8 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EGO27862.1 - 0.72 9.7 9.8 1.4 8.7 6.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EGO27862.1 - 1.1 9.6 9.6 4.1 7.8 5.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EMP24_GP25L PF01105.19 EGO27862.1 - 1.3 8.6 5.2 0.73 9.5 0.6 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Syntaxin-6_N PF09177.6 EGO27862.1 - 1.5 9.2 6.0 2.6 8.5 0.6 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 EGO27862.1 - 2.9 7.9 9.9 1.7 8.7 4.5 2.1 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Striatin PF08232.7 EGO27862.1 - 3.6 7.9 9.5 3 8.1 5.1 2.1 1 1 1 2 2 2 0 Striatin family DUF2205 PF10224.4 EGO27862.1 - 5.2 6.7 10.2 0.43 10.1 0.5 2.8 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 EGO27862.1 - 9.6 6.5 8.9 59 4.0 6.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) RhoGEF PF00621.15 EGO27863.1 - 4.2e-20 72.3 1.8 2.7e-15 56.7 0.5 3.6 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.24 EGO27863.1 - 0.0063 16.6 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 PH domain LRR_1 PF00560.28 EGO27864.1 - 9.1e-14 49.3 4.2 2.2 8.6 0.3 7.2 6 0 0 6 6 6 6 Leucine Rich Repeat LRR_6 PF13516.1 EGO27864.1 - 1.3e-13 49.4 4.8 0.3 11.2 0.0 8.7 10 1 1 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.2 EGO27864.1 - 2.1e-12 46.3 3.6 0.07 12.7 0.0 6.7 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGO27864.1 - 8.6e-08 31.1 10.2 2 8.9 0.0 7.6 7 1 0 7 7 7 3 Leucine rich repeat LRR_8 PF13855.1 EGO27864.1 - 1.8e-06 27.5 10.2 0.52 10.1 0.0 5.8 4 2 1 5 5 5 3 Leucine rich repeat Amidohydro_4 PF13147.1 EGO27865.1 - 1.9e-21 77.3 1.6 3e-18 66.8 0.0 3.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGO27865.1 - 2.5e-14 52.8 0.3 1.8e-10 40.4 0.0 2.9 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO27865.1 - 1.9e-07 31.1 0.1 0.00017 21.3 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EGO27865.1 - 4.3e-07 29.5 2.6 4e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Hyccin PF09790.4 EGO27865.1 - 0.35 9.6 0.0 1.6 7.5 0.0 1.9 2 0 0 2 2 2 0 Hyccin Myb_DNA-bind_6 PF13921.1 EGO27866.1 - 1.2e-17 63.7 6.2 1.3e-11 44.4 0.1 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO27866.1 - 2.3e-16 59.5 6.1 5e-08 32.8 0.0 3.5 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO27866.1 - 0.0003 20.8 7.5 0.0011 19.0 2.8 3.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MbeD_MobD PF04899.7 EGO27866.1 - 0.058 13.2 0.2 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 MbeD/MobD like DUF2052 PF09747.4 EGO27867.1 - 6.5e-10 39.2 13.6 9.6e-10 38.6 9.4 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF676 PF05057.9 EGO27869.1 - 3.1e-07 29.9 0.0 7e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EGO27869.1 - 8e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO27869.1 - 2.3e-05 24.1 0.0 6.2e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGO27869.1 - 4.7e-05 23.0 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO27869.1 - 0.00037 20.1 0.0 0.00098 18.7 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EGO27869.1 - 0.0021 17.6 0.1 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EGO27869.1 - 0.0029 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EGO27869.1 - 0.036 13.6 0.1 0.071 12.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 EGO27869.1 - 0.04 13.2 0.0 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 EGO27869.1 - 0.059 12.4 0.0 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 EGO27869.1 - 0.06 12.3 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase F-box-like PF12937.2 EGO27870.1 - 1.9e-12 46.6 3.9 1.9e-12 46.6 2.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EGO27870.1 - 1e-10 41.0 5.8 0.061 12.9 0.0 6.8 5 3 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO27870.1 - 0.0012 18.5 14.7 0.95 9.2 0.1 6.1 5 1 2 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 EGO27870.1 - 0.01 15.8 10.7 86 3.6 0.0 8.6 10 1 0 10 10 10 0 Leucine Rich repeat F-box PF00646.28 EGO27870.1 - 0.01 15.4 2.2 0.01 15.4 1.5 3.7 3 0 0 3 3 3 0 F-box domain LSM PF01423.17 EGO27871.1 - 2.4e-19 68.6 0.1 2.9e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain 2OG-FeII_Oxy_3 PF13640.1 EGO27872.1 - 0.017 15.6 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF202 PF02656.10 EGO27873.1 - 2.5e-13 50.0 3.2 2.5e-13 50.0 2.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.6 EGO27873.1 - 0.34 10.5 4.0 0.75 9.4 0.5 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Myb_DNA-bind_6 PF13921.1 EGO27874.1 - 2.1e-06 27.7 0.3 4.8e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO27874.1 - 0.014 15.3 0.8 0.028 14.4 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA PF00004.24 EGO27875.1 - 5.2e-22 78.4 0.0 7.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO27875.1 - 0.00066 19.8 0.2 0.0043 17.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EGO27875.1 - 0.0072 16.0 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGO27875.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EGO27875.1 - 0.075 12.7 0.2 0.39 10.3 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EGO27875.1 - 0.083 12.8 0.1 1.6 8.6 0.0 2.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EGO27875.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EGO27875.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EGO27875.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI LIN37 PF15306.1 EGO27876.1 - 0.078 12.9 0.1 0.096 12.6 0.1 1.1 1 0 0 1 1 1 0 LIN37 Pkinase PF00069.20 EGO27877.1 - 4.7e-69 232.4 0.0 6.6e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27877.1 - 1.2e-46 158.8 0.0 1.7e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO27877.1 - 1.5e-06 27.3 0.0 0.00011 21.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Sars6 PF12133.3 EGO27877.1 - 0.037 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Ribosomal_L29 PF00831.18 EGO27879.1 - 4.6e-19 67.8 1.1 4.6e-19 67.8 0.8 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein MitMem_reg PF13012.1 EGO27879.1 - 0.0057 16.7 0.3 0.017 15.1 0.0 1.9 1 1 1 2 2 2 1 Maintenance of mitochondrial structure and function Vmethyltransf_C PF08456.5 EGO27879.1 - 0.06 12.7 0.4 0.063 12.6 0.3 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Phospholamban PF04272.9 EGO27879.1 - 0.15 11.4 0.2 0.15 11.4 0.1 1.6 2 0 0 2 2 2 0 Phospholamban MRP-L47 PF06984.8 EGO27879.1 - 0.25 11.2 3.7 0.38 10.6 1.5 2.0 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Microtub_assoc PF07989.6 EGO27879.1 - 2.5 7.9 7.2 0.37 10.6 0.2 2.6 2 1 1 3 3 3 0 Microtubule associated His_biosynth PF00977.16 EGO27880.1 - 5.6e-33 114.1 0.0 4.5e-32 111.1 0.0 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EGO27880.1 - 0.096 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Fe-ADH PF00465.14 EGO27881.1 - 1e-87 294.1 0.0 1.4e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGO27881.1 - 1e-12 47.9 0.0 5.4e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DSBA PF01323.15 EGO27881.1 - 0.048 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Asp PF00026.18 EGO27882.1 - 4.4e-34 118.1 0.8 1e-32 113.6 0.5 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO27882.1 - 0.0016 18.4 2.8 0.052 13.5 0.1 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EGO27882.1 - 0.033 14.0 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease 5_3_exonuc PF01367.15 EGO27882.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Asp_protease_2 PF13650.1 EGO27882.1 - 0.067 13.6 0.0 12 6.4 0.0 3.3 2 1 0 2 2 2 0 Aspartyl protease Herpes_gE PF02480.11 EGO27882.1 - 0.085 11.1 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EGO27882.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PepSY_TM_2 PF13703.1 EGO27882.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix PPR_2 PF13041.1 EGO27883.1 - 7.2e-14 51.4 2.5 7.6e-09 35.4 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EGO27883.1 - 0.00059 19.9 0.5 2.1 8.8 0.0 4.3 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 EGO27883.1 - 0.0016 18.2 3.8 1.5 9.0 0.0 3.9 4 0 0 4 4 4 1 PPR repeat RPM2 PF08579.6 EGO27883.1 - 0.06 13.4 0.0 0.67 10.0 0.0 2.1 1 1 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Ribophorin_I PF04597.9 EGO27885.1 - 1.3e-117 392.9 0.3 1.5e-117 392.7 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I Fimbrial_PilY2 PF14481.1 EGO27885.1 - 0.057 12.8 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 Ribosomal_L22 PF00237.14 EGO27886.1 - 2.4e-20 72.4 1.3 2.7e-20 72.2 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF3546 PF12066.3 EGO27886.1 - 0.0048 16.9 0.5 0.013 15.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ThiC PF01964.13 EGO27886.1 - 0.12 10.8 1.8 0.18 10.2 1.2 1.3 1 1 0 1 1 1 0 ThiC family GILT PF03227.11 EGO27887.1 - 4.2e-08 33.0 0.2 8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Cid2 PF09774.4 EGO27888.1 - 8.5e-31 107.1 3.7 1.3e-30 106.4 2.5 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 zf-H2C2_2 PF13465.1 EGO27889.1 - 1.6e-07 31.2 8.0 0.0053 16.9 0.5 3.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO27889.1 - 1.1e-05 25.4 9.2 0.0018 18.4 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO27889.1 - 0.0022 18.2 14.3 0.019 15.2 0.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGO27889.1 - 0.008 16.2 0.4 0.036 14.2 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO27889.1 - 0.03 14.5 0.4 0.14 12.4 0.2 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EGO27889.1 - 0.12 12.7 4.5 0.6 10.5 0.8 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger Cut8_N PF14482.1 EGO27890.1 - 1.4 8.9 4.0 3.4 7.7 2.8 1.8 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Kelch_3 PF13415.1 EGO27892.1 - 1.2e-05 25.3 3.2 0.072 13.2 0.1 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain MFS_1 PF07690.11 EGO27894.1 - 3.9e-18 65.2 5.5 5.2e-18 64.8 3.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO27894.1 - 1.5e-05 23.7 5.4 2.2e-05 23.2 3.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Spc97_Spc98 PF04130.8 EGO27895.1 - 3.1e-114 382.2 0.2 5.3e-114 381.5 0.1 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family E1-E2_ATPase PF00122.15 EGO27896.1 - 1.1e-44 152.1 1.2 3.5e-44 150.5 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGO27896.1 - 7e-42 144.2 0.0 1.3e-41 143.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO27896.1 - 1.3e-17 64.6 0.0 2.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGO27896.1 - 8.9e-15 54.5 2.3 1.2e-08 34.9 0.8 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EGO27896.1 - 0.0036 16.9 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MafB19-deam PF14437.1 EGO27896.1 - 0.16 11.5 0.2 14 5.2 0.1 2.3 2 0 0 2 2 2 0 MafB19-like deaminase His_Phos_2 PF00328.17 EGO27897.1 - 8.1e-83 278.6 0.0 1.4e-82 277.7 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EGO27897.1 - 3.7e-07 29.8 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Exo_endo_phos PF03372.18 EGO27898.1 - 1.4e-21 77.5 0.5 1.8e-21 77.2 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EGO27899.1 - 0.00073 19.3 27.7 0.082 12.8 4.6 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EGO27899.1 - 0.48 10.1 28.8 0.18 11.5 0.7 4.2 3 1 1 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO27899.1 - 3.3 7.5 15.9 1.1 9.0 0.5 3.5 2 1 1 3 3 3 0 Zinc knuckle ABC_tran PF00005.22 EGO27900.1 - 1.7e-17 64.0 0.0 5.3e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO27900.1 - 7.3e-12 45.8 0.1 4.5e-06 26.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGO27900.1 - 9.5e-06 24.9 0.0 0.057 12.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EGO27900.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO27900.1 - 0.00037 19.9 0.1 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGO27900.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EGO27900.1 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EGO27900.1 - 0.013 14.7 0.2 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO27900.1 - 0.018 15.3 0.1 0.029 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGO27900.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EGO27900.1 - 0.033 14.1 0.3 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO27900.1 - 0.041 14.6 0.5 0.098 13.4 0.3 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO27900.1 - 0.046 13.1 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 EGO27900.1 - 0.055 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGO27900.1 - 0.071 13.2 0.2 0.23 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO27900.1 - 0.074 12.7 0.1 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EGO27900.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EGO27900.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 EGO27900.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Opy2 PF09463.5 EGO27901.1 - 7.3e-06 25.9 18.6 1.3e-05 25.1 12.9 1.4 1 0 0 1 1 1 1 Opy2 protein VSP PF03302.8 EGO27901.1 - 0.00018 20.2 5.8 0.0003 19.5 4.0 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.10 EGO27901.1 - 0.047 13.2 3.4 0.59 9.7 0.6 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF4366 PF14283.1 EGO27901.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PTPS_related PF10131.4 EGO27901.1 - 0.15 10.1 0.4 0.21 9.6 0.3 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein UQ_con PF00179.21 EGO27902.1 - 7.8e-20 70.7 0.0 1.7e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 EGO27902.1 - 0.00014 21.6 5.0 0.00031 20.5 3.5 1.5 1 0 0 1 1 1 1 IBR domain UBA PF00627.26 EGO27902.1 - 0.11 12.3 1.8 0.17 11.7 0.1 2.4 2 0 0 2 2 2 0 UBA/TS-N domain Mito_carr PF00153.22 EGO27903.1 - 1e-53 179.0 2.8 4.2e-18 64.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 EGO27903.1 - 0.0088 15.7 0.4 0.51 10.0 0.1 2.5 2 0 0 2 2 2 1 PrcB C-terminal GTP_EFTU PF00009.22 EGO27904.1 - 3.3e-48 163.6 0.0 4.6e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO27904.1 - 2e-25 88.8 0.1 5.5e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO27904.1 - 4.2e-07 29.9 0.8 8.9e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO27904.1 - 1.9e-05 24.5 0.0 5.6e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO27904.1 - 0.021 15.3 0.0 0.074 13.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Glyco_hydro_3_C PF01915.17 EGO27904.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Gtr1_RagA PF04670.7 EGO27904.1 - 0.17 11.0 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Sec7 PF01369.15 EGO27905.1 - 5.6e-65 218.5 0.0 1.5e-64 217.1 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGO27905.1 - 1.9e-55 186.8 8.2 2.7e-55 186.3 3.3 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGO27905.1 - 1.5e-30 104.5 7.4 2.6e-30 103.7 0.1 4.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Sec5 PF15469.1 EGO27905.1 - 0.012 15.3 0.2 0.058 13.1 0.1 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec5 HEAT PF02985.17 EGO27905.1 - 0.048 13.7 0.1 8.3 6.7 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat DS PF01916.12 EGO27906.1 - 6.1e-136 452.3 0.0 7.1e-136 452.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.15 EGO27907.1 - 5.6e-78 261.2 2.0 6.4e-78 261.0 1.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1943 PF09172.6 EGO27907.1 - 0.053 12.3 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) HPP PF04982.8 EGO27908.1 - 2.8e-39 133.6 7.9 2.8e-39 133.6 5.5 1.7 2 0 0 2 2 2 1 HPP family CcmD PF04995.9 EGO27908.1 - 0.71 9.6 3.4 0.46 10.2 0.2 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Aminotran_1_2 PF00155.16 EGO27909.1 - 1.2e-09 37.6 0.0 4.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Polyketide_cyc PF03364.15 EGO27911.1 - 1.1e-23 83.6 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Chitin_synth_1 PF01644.12 EGO27912.1 - 2.1e-65 219.4 0.1 3.3e-65 218.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGO27912.1 - 1.9e-27 94.7 0.5 4.2e-27 93.6 0.4 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGO27912.1 - 9.1e-23 80.4 0.0 1.6e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGO27912.1 - 2.1e-07 30.9 0.0 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF4107 PF13389.1 EGO27912.1 - 0.18 11.4 2.1 0.41 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Spo12 PF05032.7 EGO27913.1 - 1.4e-07 30.9 0.5 2.6e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Spo12 family Glyco_hydro_2 PF00703.16 EGO27915.1 - 4.8e-09 36.6 0.6 1.3e-08 35.2 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EGO27915.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EGO27915.1 - 0.0092 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.11 EGO27916.1 - 2e-36 125.4 36.3 2.7e-36 125.0 24.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA_SAD PF07973.9 EGO27917.1 - 0.00045 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EGO27917.1 - 0.024 12.9 0.5 0.04 12.1 0.3 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) DUF971 PF06155.7 EGO27917.1 - 0.11 12.9 0.0 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF971) zf-RING_2 PF13639.1 EGO27918.1 - 6e-10 38.7 5.5 4e-09 36.1 3.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO27918.1 - 1.7e-07 31.1 3.8 9.7e-07 28.7 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO27918.1 - 1.9e-06 27.4 0.1 4e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO27918.1 - 2.8e-06 26.9 1.7 8.2e-06 25.4 1.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGO27918.1 - 5.2e-06 26.4 0.3 8.3e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO27918.1 - 0.00013 21.5 4.3 0.0021 17.6 3.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGO27918.1 - 0.00032 20.2 0.9 0.0021 17.6 0.2 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGO27918.1 - 0.00051 19.8 1.1 0.0012 18.6 0.8 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGO27918.1 - 0.024 14.3 5.3 0.027 14.1 1.9 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EGO27918.1 - 0.056 12.9 0.5 0.15 11.5 0.3 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGO27918.1 - 0.12 12.2 6.4 0.11 12.3 1.0 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_3 PF14369.1 EGO27918.1 - 0.31 11.0 4.1 11 6.1 0.4 2.6 2 0 0 2 2 2 0 zinc-finger MFS_1 PF07690.11 EGO27919.1 - 5.8e-40 137.0 42.5 5.4e-38 130.6 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EGO27919.1 - 3.1 8.2 5.9 0.45 10.9 0.2 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NIF PF03031.13 EGO27920.1 - 4.2e-51 172.7 0.0 7.2e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SLD3 PF08639.5 EGO27923.1 - 0.00013 20.8 16.8 0.0015 17.2 11.7 2.3 1 1 0 1 1 1 1 DNA replication regulator SLD3 DEAD PF00270.24 EGO27924.1 - 7.1e-46 155.7 0.0 1.5e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO27924.1 - 2.3e-27 94.6 0.0 7.9e-27 92.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO27924.1 - 7.2e-05 22.7 0.0 0.0011 18.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RTA1 PF04479.8 EGO27925.1 - 4.6e-14 52.4 0.5 4.7e-14 52.4 0.3 1.0 1 0 0 1 1 1 1 RTA1 like protein Yip1 PF04893.12 EGO27925.1 - 0.0084 15.6 2.2 0.0099 15.3 1.5 1.0 1 0 0 1 1 1 1 Yip1 domain Zn_clus PF00172.13 EGO27926.1 - 0.00014 21.7 11.8 0.00014 21.7 8.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleo_P87 PF07267.6 EGO27927.1 - 0.13 10.9 0.7 0.19 10.3 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIID-18kDa PF02269.11 EGO27928.1 - 7.7e-32 108.9 0.1 1.6e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Sec5 PF15469.1 EGO27928.1 - 0.054 13.2 0.2 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component Sec5 PAPS_reduct PF01507.14 EGO27929.1 - 5.8e-38 130.4 0.0 7.4e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HlyD PF00529.15 EGO27929.1 - 0.16 11.2 0.1 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 HlyD family secretion protein Ribonucleas_3_3 PF14622.1 EGO27930.1 - 7.5e-18 64.7 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGO27930.1 - 1.2e-14 54.6 0.0 2.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EGO27930.1 - 3.4e-09 37.1 0.0 6.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif LPP20 PF02169.11 EGO27930.1 - 0.078 13.0 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 LPP20 lipoprotein Coiled-coil_56 PF09813.4 EGO27931.1 - 6.6e-07 29.2 0.0 9.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.10 EGO27932.1 - 0.08 12.6 5.2 0.56 9.9 3.6 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa PI3_PI4_kinase PF00454.22 EGO27933.1 - 3.4e-45 154.3 0.0 2.6e-44 151.4 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EGO27933.1 - 4.2e-28 98.3 0.6 8.8e-23 80.8 0.1 2.5 1 1 1 2 2 2 2 FAT domain UME PF08064.8 EGO27933.1 - 2.3e-25 88.6 0.0 1.9e-24 85.6 0.0 2.8 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EGO27933.1 - 3e-11 42.5 0.9 6.6e-11 41.4 0.1 2.1 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.1 EGO27933.1 - 0.035 14.4 0.0 0.18 12.1 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat GATA PF00320.22 EGO27938.1 - 1e-08 34.3 4.3 1e-08 34.3 2.9 1.7 2 0 0 2 2 2 1 GATA zinc finger ArfGap PF01412.13 EGO27938.1 - 0.18 11.5 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf APC_CDC26 PF10471.4 EGO27938.1 - 3 8.6 9.1 11 6.8 4.6 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 CI-B14_5a PF07347.7 EGO27941.1 - 0.044 13.5 0.5 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) PHD PF00628.24 EGO27944.1 - 1.6e-08 34.1 5.2 2.2e-08 33.6 3.6 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EGO27944.1 - 0.1 12.7 1.7 0.11 12.6 0.4 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain TPR_4 PF07721.9 EGO27944.1 - 0.4 11.2 4.8 6.4 7.5 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Rhomboid PF01694.17 EGO27949.1 - 7.3e-07 29.3 6.6 7.3e-07 29.3 4.6 1.5 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.10 EGO27949.1 - 0.00041 19.9 6.8 0.00062 19.3 4.7 1.3 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 EGO27949.1 - 0.0033 17.7 1.8 0.0043 17.3 0.5 1.8 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Transposase_28 PF04195.7 EGO27949.1 - 0.008 15.4 2.6 0.012 14.9 1.8 1.2 1 0 0 1 1 1 1 Putative gypsy type transposon eIF-3_zeta PF05091.7 EGO27950.1 - 3.1e-184 613.4 0.0 3.7e-184 613.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.17 EGO27951.1 - 2.9e-18 65.2 0.1 4.6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27951.1 - 1.1e-11 44.5 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27951.1 - 9.5e-08 31.7 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec62 PF03839.11 EGO27951.1 - 0.82 9.0 7.3 1.1 8.5 5.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RNase_H2-Ydr279 PF09468.5 EGO27951.1 - 9 5.3 13.0 14 4.7 9.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 EGO27951.1 - 9.3 6.0 9.9 14 5.4 6.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSCB_C PF07743.8 EGO27952.1 - 1.2e-13 51.3 5.5 1.3e-13 51.2 2.7 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGO27952.1 - 5.9e-09 35.5 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 EGO27952.1 - 0.009 15.8 0.4 0.018 14.8 0.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 EGO27952.1 - 0.82 9.4 4.7 1.9 8.2 3.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 EGO27952.1 - 1.4 8.5 4.4 3.1 7.4 3.0 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGO27952.1 - 2.4 7.4 8.4 6.1 6.1 5.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Prenyltrans PF00432.16 EGO27953.1 - 6.9e-58 191.8 9.8 1.2e-12 47.1 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO27953.1 - 2.9e-37 127.5 0.0 2e-16 60.3 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO27953.1 - 5.9e-10 39.1 0.0 3.4e-06 27.0 0.0 3.1 1 1 2 3 3 3 2 Prenyltransferase-like Rhodanese PF00581.15 EGO27954.1 - 3.6e-07 30.5 0.0 1e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DUF2617 PF10936.3 EGO27955.1 - 0.098 12.2 0.1 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF2617 APH PF01636.18 EGO27958.1 - 0.00028 20.7 0.4 0.003 17.3 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.6 EGO27958.1 - 0.0028 16.9 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EGO27958.1 - 0.0056 16.0 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EGO27958.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EGO27958.1 - 0.034 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EGO27958.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.9 EGO27958.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERM PF00769.14 EGO27959.1 - 0.79 9.2 4.2 0.44 10.0 0.4 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1832 PF08870.6 EGO27960.1 - 0.1 12.3 0.2 0.63 9.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1832) zf-CCHC_3 PF13917.1 EGO27962.1 - 8.1e-07 28.6 1.6 8.9e-07 28.5 1.1 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO27962.1 - 1.8e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO27962.1 - 0.11 12.0 4.1 0.15 11.6 2.8 1.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4606 PF15379.1 EGO27962.1 - 0.89 9.6 3.0 1.6 8.8 2.0 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) Retrotrans_gag PF03732.12 EGO27963.1 - 6.8e-08 32.4 0.3 6.8e-08 32.4 0.2 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO27963.1 - 2.8e-06 26.9 2.2 5e-06 26.1 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO27963.1 - 0.018 14.7 2.2 0.018 14.7 1.5 2.0 2 0 0 2 2 2 0 Zinc knuckle Herpes_UL55 PF04537.7 EGO27963.1 - 0.052 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein DUF4381 PF14316.1 EGO27966.1 - 0.055 13.5 0.2 0.059 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-CCHC PF00098.18 EGO27967.1 - 6.6e-08 32.1 2.7 1.4e-07 31.0 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO27967.1 - 0.18 11.4 0.9 0.33 10.6 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 EGO27968.1 - 7.3e-09 35.1 0.0 3.7e-07 29.5 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO27968.1 - 0.029 13.4 0.0 0.074 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase adh_short PF00106.20 EGO27969.1 - 1.6e-24 86.7 0.1 6.5e-24 84.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO27969.1 - 5e-19 69.0 0.7 1.1e-18 67.9 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO27969.1 - 1.7e-12 47.4 0.3 9.2e-12 44.9 0.2 2.0 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EGO27969.1 - 7.7e-05 23.0 0.1 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 EGO27969.1 - 0.00053 19.5 0.5 0.0034 16.8 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGO27969.1 - 0.0085 15.7 0.3 0.017 14.7 0.2 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EGO27969.1 - 0.014 14.5 0.2 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EGO27969.1 - 0.056 12.3 0.1 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGO27969.1 - 0.078 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGO27969.1 - 0.08 11.6 0.1 0.16 10.6 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2353 PF09789.4 EGO27970.1 - 7.2e-06 25.4 23.9 0.0041 16.4 3.6 2.9 2 1 1 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) DUF1192 PF06698.6 EGO27970.1 - 0.4 10.5 7.2 0.091 12.5 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_S46 PF10459.4 EGO27970.1 - 3 6.1 9.2 4.4 5.5 6.4 1.1 1 0 0 1 1 1 0 Peptidase S46 NYD-SP28_assoc PF14775.1 EGO27970.1 - 3.7 7.3 8.6 2.6 7.8 0.9 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain RasGAP PF00616.14 EGO27971.1 - 4.9e-33 114.4 0.0 1.1e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EGO27971.1 - 1e-09 38.4 0.1 2.8e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 EGO27971.1 - 2.4e-07 30.8 0.4 9.4e-07 28.8 0.3 2.1 1 0 0 1 1 1 1 Cell morphogenesis C-terminal cEGF PF12662.2 EGO27971.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like RRM_1 PF00076.17 EGO27972.1 - 1.1e-31 108.2 0.0 3.7e-16 58.5 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO27972.1 - 3e-19 68.7 0.0 1.1e-10 41.3 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO27972.1 - 6.1e-12 45.1 0.0 9.4e-10 38.2 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO27972.1 - 4.5e-06 26.4 0.3 1.7e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EGO27972.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Band_7 PF01145.20 EGO27973.1 - 3.2e-23 82.5 4.3 5.3e-23 81.8 2.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family EVE PF01878.13 EGO27974.1 - 2.1e-27 95.8 0.0 4.5e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 EVE domain FLO_LFY PF01698.11 EGO27974.1 - 0.31 9.8 8.1 0.42 9.4 5.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 EGO27974.1 - 6.3 6.5 9.5 9.2 6.0 6.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Acyltransferase PF01553.16 EGO27975.1 - 1.4e-29 102.2 0.0 1.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GDPD PF03009.12 EGO27976.1 - 1.7e-31 109.6 0.0 2.3e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EGO27976.1 - 1.3e-05 25.1 1.3 1.3e-05 25.1 0.9 2.6 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Na_H_Exchanger PF00999.16 EGO27980.1 - 1.4e-56 191.7 47.1 2.3e-56 190.9 32.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.12 EGO27981.1 - 2.7e-64 215.1 6.8 3e-64 214.9 4.7 1.0 1 0 0 1 1 1 1 G10 protein SDA1 PF05285.7 EGO27982.1 - 0.85 8.8 16.8 1.2 8.3 11.6 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.6 EGO27982.1 - 1.2 8.6 12.9 2.7 7.4 8.9 1.5 1 0 0 1 1 1 0 PPP4R2 DUF1510 PF07423.6 EGO27982.1 - 4.6 6.5 11.3 6.6 6.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Lip_prot_lig_C PF10437.4 EGO27983.1 - 4.7e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus CHCH PF06747.8 EGO27984.1 - 0.0012 18.6 3.9 0.0012 18.6 2.7 2.5 2 1 0 2 2 2 1 CHCH domain LSM PF01423.17 EGO27984.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 LSM domain YqzH PF14164.1 EGO27984.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 YqzH-like protein Defensin_1 PF00323.14 EGO27984.1 - 0.48 10.8 3.4 2.3 8.6 0.5 2.3 2 0 0 2 2 2 0 Mammalian defensin Pet191_N PF10203.4 EGO27984.1 - 1.5 8.9 10.9 0.63 10.1 4.4 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EGO27984.1 - 4.8 7.2 10.9 1 9.4 3.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EGO27984.1 - 9.1 6.1 12.9 17 5.2 3.0 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sigma70_r1_2 PF00140.15 EGO27985.1 - 0.027 14.1 0.1 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF498 PF04430.9 EGO27986.1 - 1.8e-30 104.7 0.0 5.3e-30 103.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) MAS20 PF02064.10 EGO27986.1 - 5.3e-16 58.6 1.3 4.2e-14 52.4 0.6 2.9 2 1 0 2 2 2 1 MAS20 protein import receptor SET PF00856.23 EGO27986.1 - 4.5e-10 40.0 0.0 7.1e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 SET domain SAF PF08666.7 EGO27986.1 - 0.00081 19.7 0.3 0.81 10.1 0.1 2.6 2 0 0 2 2 2 2 SAF domain Ecl1 PF12855.2 EGO27986.1 - 0.079 12.2 1.0 0.16 11.2 0.7 1.5 1 0 0 1 1 1 0 Life-span regulatory factor SMK-1 PF04802.10 EGO27987.1 - 6e-63 211.8 4.7 6.6e-62 208.4 3.3 2.3 1 1 0 1 1 1 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 EGO27987.1 - 0.015 15.0 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 WH1 domain zf-C2H2 PF00096.21 EGO27988.1 - 8.6e-07 28.9 12.4 0.00021 21.4 0.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGO27988.1 - 4.2e-06 26.7 1.1 0.00083 19.4 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGO27988.1 - 2.9e-05 23.6 2.9 0.011 15.4 0.3 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 EGO27988.1 - 3.9e-05 23.6 10.7 0.0052 17.0 0.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EGO27988.1 - 4.6e-05 23.4 3.2 0.0001 22.3 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGO27988.1 - 0.00021 21.3 3.2 0.0069 16.4 0.0 2.4 2 1 1 3 3 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EGO27988.1 - 0.00033 20.8 3.8 0.36 11.1 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGO27988.1 - 0.0057 16.5 4.1 0.05 13.5 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Sgf11 PF08209.6 EGO27988.1 - 0.0074 15.5 0.3 0.17 11.2 0.0 2.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Rad50_zn_hook PF04423.9 EGO27988.1 - 0.029 13.8 0.2 5.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.7 EGO27988.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HTH_31 PF13560.1 EGO27988.1 - 0.053 13.7 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain C1_4 PF07975.7 EGO27988.1 - 0.069 13.1 2.2 0.18 11.8 1.3 1.8 1 1 1 2 2 2 0 TFIIH C1-like domain PHD PF00628.24 EGO27988.1 - 0.099 12.3 1.4 0.3 10.8 1.0 1.8 1 1 0 1 1 1 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 EGO27988.1 - 0.1 12.4 0.7 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain LIM PF00412.17 EGO27988.1 - 0.18 11.9 2.9 7.5 6.7 0.1 2.4 1 1 1 2 2 2 0 LIM domain zf-RING_3 PF14369.1 EGO27988.1 - 0.42 10.6 2.9 4.5 7.3 2.0 2.4 1 1 0 1 1 1 0 zinc-finger zf-RING_4 PF14570.1 EGO27988.1 - 0.46 10.1 2.9 1.3 8.6 2.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 EGO27988.1 - 0.66 9.9 3.5 0.85 9.6 0.4 2.2 1 1 1 2 2 2 0 Zinc ribbon domain AceK PF06315.6 EGO27989.1 - 0.12 10.6 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) CNH PF00780.17 EGO27990.1 - 0.00012 21.6 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 CNH domain TRP PF06011.7 EGO27991.1 - 4.8e-47 160.5 24.5 3.1e-46 157.8 17.0 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO27991.1 - 0.00066 19.7 0.5 0.0013 18.7 0.4 1.4 1 0 0 1 1 1 1 ML-like domain UPF0029 PF01205.14 EGO27992.1 - 3.7e-28 97.3 0.0 6e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGO27992.1 - 3.2e-05 23.7 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain AvrL567-A PF11529.3 EGO27992.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A FAA_hydrolase PF01557.13 EGO27994.1 - 3.6e-52 176.9 0.0 5e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DDE_1 PF03184.14 EGO27996.1 - 1.9e-09 36.9 0.0 3.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Proteasome PF00227.21 EGO27997.1 - 9.7e-61 204.3 0.0 1.4e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO27997.1 - 3.2e-09 35.9 0.2 8.5e-09 34.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DDE_1 PF03184.14 EGO28001.1 - 2.2e-13 49.8 0.0 4.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO28001.1 - 0.00029 20.5 0.0 0.00087 19.0 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 EGO28002.1 - 1.1e-08 34.5 0.0 4.8e-08 32.4 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28002.1 - 0.0084 15.2 0.0 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO28004.1 - 2.6e-06 26.8 0.0 1.6e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase PF00069.20 EGO28005.1 - 2.9e-09 36.4 0.0 1e-08 34.6 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain MFMR PF07777.6 EGO28007.1 - 0.083 12.8 3.8 0.11 12.4 2.6 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR DUF3943 PF13084.1 EGO28008.1 - 0.012 15.1 0.8 0.079 12.5 0.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3943) LysM PF01476.15 EGO28012.1 - 9.4e-17 60.6 0.2 2.2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain DUF3159 PF11361.3 EGO28019.1 - 0.016 14.7 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) YbjM PF11045.3 EGO28019.1 - 0.098 12.4 2.2 0.1 12.3 0.3 1.7 1 1 1 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae Vezatin PF12632.2 EGO28019.1 - 9.9 5.1 9.9 4.2 6.3 0.1 2.5 3 0 0 3 3 3 0 Mysoin-binding motif of peroxisomes bPH_3 PF14470.1 EGO28021.1 - 0.00029 21.0 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial PH domain GRAM PF02893.15 EGO28021.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.3 EGO28021.1 - 0.013 15.2 0.0 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 SNAP PF14938.1 EGO28022.1 - 5.8e-104 347.1 17.2 6.6e-104 347.0 11.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EGO28022.1 - 4.2e-05 23.0 7.4 0.067 13.0 0.1 5.6 4 2 1 6 6 6 1 Tetratricopeptide repeat PspA_IM30 PF04012.7 EGO28022.1 - 0.015 14.6 5.0 0.59 9.4 2.8 2.2 1 1 1 2 2 2 0 PspA/IM30 family TPR_12 PF13424.1 EGO28022.1 - 0.027 14.4 10.5 0.069 13.0 2.5 3.5 1 1 1 3 3 3 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 EGO28022.1 - 0.044 12.6 4.5 0.078 11.8 1.8 2.1 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_11 PF13414.1 EGO28022.1 - 0.047 13.3 10.1 0.32 10.6 0.6 3.5 1 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.1 EGO28022.1 - 0.1 13.0 8.9 11 6.7 0.0 5.5 4 1 2 6 6 6 0 Tetratricopeptide repeat NSF PF02071.15 EGO28022.1 - 3.3 8.6 7.3 40 5.4 0.0 5.7 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.1 EGO28022.1 - 3.9 8.2 11.5 5.4 7.8 0.2 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EGO28023.1 - 4.7e-42 143.9 0.0 1.4e-22 80.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28023.1 - 2.1e-13 49.9 0.0 2.6e-10 39.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGO28023.1 - 0.00014 21.6 0.2 0.00033 20.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO28023.1 - 0.13 11.2 0.0 0.88 8.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like UCH PF00443.24 EGO28024.1 - 5.1e-36 124.1 0.0 7.1e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO28024.1 - 3e-12 46.5 0.0 2.3e-11 43.6 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DM PF00751.13 EGO28024.1 - 1 8.9 7.6 3.4 7.2 0.7 2.7 2 0 0 2 2 2 0 DM DNA binding domain DUF1992 PF09350.5 EGO28026.1 - 3e-18 65.3 0.1 8.5e-18 63.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Aldedh PF00171.17 EGO28027.1 - 1.8e-100 336.4 0.0 2.2e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_isomerase PF00160.16 EGO28029.1 - 4.4e-37 127.6 0.0 6.5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EGO28029.1 - 9.7e-16 57.1 0.0 1.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO28029.1 - 2.7e-11 43.2 0.0 6.8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO28029.1 - 3.5e-08 33.1 0.0 6.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SmpA_OmlA PF04355.8 EGO28029.1 - 0.089 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 SmpA / OmlA family WD40 PF00400.27 EGO28030.1 - 1.2e-44 148.5 7.4 2e-08 33.8 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EGO28030.1 - 0.0028 17.4 0.0 0.22 11.1 0.0 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGO28030.1 - 0.018 13.3 0.0 0.038 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EGO28030.1 - 0.047 11.9 0.0 0.44 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 EGO28030.1 - 0.3 11.4 4.0 0.91 9.8 0.0 3.6 5 0 0 5 5 5 0 PQQ-like domain ATG22 PF11700.3 EGO28031.1 - 7.1e-101 338.0 23.0 8.1e-101 337.8 15.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGO28031.1 - 6.6e-15 54.6 32.0 4.6e-08 32.1 7.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily RRM_3 PF08777.6 EGO28033.1 - 6.1e-05 22.8 0.1 0.0035 17.1 0.0 3.0 2 1 0 2 2 2 1 RNA binding motif RRM_6 PF14259.1 EGO28033.1 - 0.0018 18.1 0.0 0.39 10.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1768 PF08719.6 EGO28034.1 - 3.2e-22 78.9 0.0 3.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) SAP18 PF06487.7 EGO28035.1 - 1.7e-25 89.1 0.0 2.3e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Cu_amine_oxid PF01179.15 EGO28036.1 - 3.2e-104 348.9 0.0 4.4e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EGO28036.1 - 2.9e-10 39.9 0.0 7.9e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EGO28036.1 - 0.00064 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.19 EGO28037.1 - 5e-79 265.9 22.0 6.1e-79 265.7 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO28037.1 - 8.3e-26 90.5 31.4 9.6e-25 87.0 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO28037.1 - 2.8e-09 35.7 3.4 2.8e-09 35.7 2.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO28037.1 - 4.7e-06 25.2 17.5 1.8e-05 23.3 3.6 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein MMPL PF03176.10 EGO28037.1 - 0.1 11.2 1.7 0.2 10.3 1.2 1.4 1 0 0 1 1 1 0 MMPL family P16-Arc PF04699.9 EGO28038.1 - 0.072 13.1 0.1 11 6.0 0.0 2.2 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) MFS_1 PF07690.11 EGO28039.1 - 1.4e-21 76.5 50.8 4.9e-11 41.9 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ubiquitin PF00240.18 EGO28040.1 - 6.9e-25 86.2 0.2 7.7e-25 86.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGO28040.1 - 5.1e-15 54.9 0.6 5.6e-15 54.7 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO28040.1 - 0.00013 22.1 0.1 0.00029 21.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF4549 PF15082.1 EGO28040.1 - 0.13 11.9 0.1 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) 2OG-FeII_Oxy_2 PF13532.1 EGO28041.1 - 1.5e-15 57.5 0.0 1.7e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGO28041.1 - 2.3e-08 34.2 0.0 3.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA PF00004.24 EGO28042.1 - 2.1e-06 27.9 0.1 4.1e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps36_ESCRT-II PF11605.3 EGO28042.1 - 0.016 14.9 0.0 0.047 13.5 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Copine PF07002.11 EGO28042.1 - 0.031 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Copine His_Phos_1 PF00300.17 EGO28043.1 - 2.4e-16 60.2 0.0 3.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PAM2 PF07145.10 EGO28043.1 - 0.19 11.3 0.3 0.46 10.1 0.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region STE3 PF02076.10 EGO28044.1 - 1.7e-90 302.9 15.1 1.7e-90 302.9 10.5 1.7 2 0 0 2 2 2 1 Pheromone A receptor PH PF00169.24 EGO28045.1 - 7.3e-13 48.6 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 PH domain CH PF00307.26 EGO28045.1 - 0.00017 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_11 PF15413.1 EGO28045.1 - 0.13 12.5 3.3 0.55 10.5 2.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Bap31 PF05529.7 EGO28045.1 - 2.1 7.7 3.3 3.3 7.1 2.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like SSDP PF04503.8 EGO28048.1 - 0.041 13.6 2.7 0.045 13.4 1.9 1.2 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP Thaumatin PF00314.12 EGO28052.1 - 2.5e-14 53.2 9.9 3.9e-14 52.6 6.9 1.3 1 0 0 1 1 1 1 Thaumatin family TraW_N PF12477.3 EGO28052.1 - 6.4 6.8 6.5 17 5.5 4.5 1.8 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal zf-MYND PF01753.13 EGO28053.1 - 9.6e-12 44.5 14.3 1.8e-11 43.6 9.9 1.5 1 0 0 1 1 1 1 MYND finger Meleagrin PF08189.6 EGO28053.1 - 0.1 12.0 8.2 0.24 10.9 5.7 1.6 1 0 0 1 1 1 0 Meleagrin/Cygnin family TPR_11 PF13414.1 EGO28055.1 - 1.6e-13 50.1 7.2 1.3e-10 40.7 0.1 3.6 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGO28055.1 - 4.9e-09 35.4 0.4 0.067 12.8 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO28055.1 - 1.5e-06 27.6 2.7 0.6 10.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.26 EGO28055.1 - 1.2e-05 24.9 0.0 5.3e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 EGO28055.1 - 0.0033 17.1 0.0 0.0086 15.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S8e PF01201.17 EGO28055.1 - 0.01 15.9 0.3 0.22 11.6 0.1 2.6 2 1 0 2 2 2 0 Ribosomal protein S8e TPR_12 PF13424.1 EGO28055.1 - 0.044 13.7 4.3 0.15 12.0 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO28055.1 - 0.086 13.5 0.0 0.086 13.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_3 PF01596.12 EGO28058.1 - 2e-44 151.1 0.1 2.5e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGO28058.1 - 4.6e-16 59.5 0.0 8.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO28058.1 - 2.2e-12 47.5 0.0 3.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO28058.1 - 2.4e-12 46.7 0.0 3.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO28058.1 - 1.5e-08 34.4 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGO28058.1 - 4.9e-08 33.0 0.0 1.3e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO28058.1 - 8.3e-06 26.2 0.0 2.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO28058.1 - 1.3e-05 24.4 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 EGO28058.1 - 0.00033 20.0 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 EGO28058.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CmcI PF04989.7 EGO28058.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_30 PF05430.6 EGO28058.1 - 0.045 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase GCD14 PF08704.5 EGO28058.1 - 0.14 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF4219 PF13961.1 EGO28059.1 - 0.0027 17.0 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) RVP_2 PF08284.6 EGO28060.1 - 0.022 14.6 0.1 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 EGO28062.1 - 4.6e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO28062.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO28062.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle tRNA-synt_1g PF09334.6 EGO28063.1 - 3.3e-105 351.9 0.0 1.2e-104 350.1 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGO28063.1 - 9.9e-22 76.6 0.1 2.9e-10 38.8 0.0 3.7 2 1 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EGO28063.1 - 3e-11 43.0 0.0 6.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Sugar_tr PF00083.19 EGO28066.1 - 7.5e-74 248.9 17.3 7.5e-74 248.9 12.0 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO28066.1 - 2.7e-26 92.1 30.8 1.3e-25 89.8 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EGO28066.1 - 0.003 16.3 2.0 0.0056 15.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EGO28066.1 - 0.0034 15.6 2.7 0.0034 15.6 1.9 2.1 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 EGO28067.1 - 1.4e-14 53.7 1.5 4.4e-14 52.1 1.1 1.9 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO28067.1 - 1.3e-08 34.5 0.1 2.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGO28067.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF2296 PF10058.4 EGO28068.1 - 7.2e-21 73.6 0.3 1.2e-20 73.0 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) SMN PF06003.7 EGO28068.1 - 0.016 14.3 0.3 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PhnA_Zn_Ribbon PF08274.7 EGO28068.1 - 0.026 14.3 0.8 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 EGO28068.1 - 0.057 13.2 2.7 0.11 12.2 0.9 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF1610 PF07754.6 EGO28068.1 - 1.7 8.8 5.2 0.25 11.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) NOB1_Zn_bind PF08772.6 EGO28068.1 - 2.3 8.0 4.3 0.67 9.8 0.6 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Hydrophobin PF01185.13 EGO28069.1 - 3.8e-23 81.7 9.0 4.7e-23 81.4 6.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin SapA PF02199.10 EGO28069.1 - 0.0053 16.4 2.0 0.0098 15.6 1.4 1.5 1 0 0 1 1 1 1 Saposin A-type domain ABC_tran PF00005.22 EGO28070.1 - 1.5e-46 158.0 0.0 1.4e-22 80.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EGO28070.1 - 2.4e-19 68.9 4.1 2.4e-19 68.9 2.8 2.2 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EGO28070.1 - 8.2e-19 68.6 0.3 0.002 18.1 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EGO28070.1 - 6.6e-10 38.3 0.2 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO28070.1 - 8.2e-09 35.7 0.0 0.00019 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EGO28070.1 - 9.1e-09 34.8 0.6 0.58 9.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO28070.1 - 9e-07 29.4 12.5 0.034 14.4 1.5 3.9 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 EGO28070.1 - 7.1e-06 25.7 0.0 0.069 12.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 EGO28070.1 - 1.3e-05 25.6 0.0 0.36 11.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EGO28070.1 - 1.3e-05 25.9 0.1 0.097 13.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EGO28070.1 - 2.6e-05 24.3 0.0 0.23 11.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EGO28070.1 - 3.6e-05 23.3 0.0 0.26 10.7 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 EGO28070.1 - 0.00021 21.6 0.1 1.1 9.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EGO28070.1 - 0.00022 21.1 0.1 0.43 10.5 0.0 3.2 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EGO28070.1 - 0.00022 20.7 0.0 0.39 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 EGO28070.1 - 0.00024 20.3 0.0 0.091 11.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGO28070.1 - 0.00072 19.0 0.0 1.5 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EGO28070.1 - 0.00084 19.4 0.5 3.6 7.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.1 EGO28070.1 - 0.0014 18.5 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGO28070.1 - 0.0016 18.3 0.0 4 7.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 EGO28070.1 - 0.0019 18.0 0.0 4.1 7.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EGO28070.1 - 0.005 16.5 0.2 2 8.1 0.0 3.2 3 0 0 3 3 3 1 NTPase G-alpha PF00503.15 EGO28070.1 - 0.0054 15.4 0.3 2.6 6.6 0.0 2.8 2 1 1 3 3 3 1 G-protein alpha subunit AAA_30 PF13604.1 EGO28070.1 - 0.0061 16.1 0.0 0.75 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGO28070.1 - 0.0073 16.0 0.5 7.3 6.2 0.0 3.3 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EGO28070.1 - 0.0075 15.7 0.4 0.98 8.8 0.0 3.1 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EGO28070.1 - 0.014 15.2 6.4 0.75 9.5 0.1 4.1 2 2 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EGO28070.1 - 0.014 14.9 0.2 4.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EGO28070.1 - 0.016 15.0 9.0 0.67 9.7 0.2 4.1 4 2 1 5 5 4 0 Domain of unknown function DUF87 cobW PF02492.14 EGO28070.1 - 0.017 14.5 0.1 6.3 6.2 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGO28070.1 - 0.02 14.6 0.0 5.5 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGO28070.1 - 0.029 14.2 1.1 2.6 8.0 0.0 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EGO28070.1 - 0.056 12.2 0.0 9 4.9 0.0 2.6 2 0 0 2 2 2 0 ArgK protein Thymidylate_kin PF02223.12 EGO28070.1 - 0.25 10.6 3.0 16 4.7 0.0 3.7 4 0 0 4 4 4 0 Thymidylate kinase Metallophos PF00149.23 EGO28071.1 - 1.5e-41 141.9 0.3 2e-41 141.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2 PF00096.21 EGO28073.1 - 5.8e-09 35.7 9.0 1.6e-06 28.0 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO28073.1 - 3.3e-08 33.4 10.1 4e-06 26.8 2.8 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO28073.1 - 2.8e-05 24.1 9.8 0.00021 21.3 1.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Dof PF02701.10 EGO28073.1 - 0.0026 17.6 0.5 0.0026 17.6 0.3 1.4 2 0 0 2 2 2 1 Dof domain, zinc finger zf-met PF12874.2 EGO28073.1 - 0.0063 16.6 3.3 0.025 14.7 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO28073.1 - 0.022 14.8 0.1 0.022 14.8 0.1 1.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding IBR PF01485.16 EGO28073.1 - 0.12 12.2 5.1 0.14 12.0 0.5 2.0 1 1 1 2 2 2 0 IBR domain zf-TRAF PF02176.13 EGO28073.1 - 0.18 12.1 5.8 0.34 11.3 4.0 1.5 1 1 0 1 1 1 0 TRAF-type zinc finger Ribosomal_L1 PF00687.16 EGO28075.1 - 2.9e-48 164.1 2.0 3.5e-48 163.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pescadillo_N PF06732.6 EGO28077.1 - 9.7e-118 392.4 0.1 9.7e-118 392.4 0.0 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EGO28077.1 - 1.8e-10 40.8 0.0 6e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain p450 PF00067.17 EGO28078.1 - 4.9e-64 216.5 0.0 7.1e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLA2_B PF01735.13 EGO28079.1 - 4.4e-104 348.3 1.3 5.7e-104 347.9 0.9 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PCI PF01399.22 EGO28080.1 - 1.8e-12 47.5 0.0 4.3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain STb_secrete PF09075.5 EGO28080.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory Spc97_Spc98 PF04130.8 EGO28082.1 - 2.7e-54 184.4 0.5 2.7e-54 184.4 0.4 2.5 3 0 0 3 3 3 1 Spc97 / Spc98 family Mgm101p PF06420.7 EGO28083.1 - 1.1e-91 304.7 0.1 1.2e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Tyrosinase PF00264.15 EGO28084.1 - 9.4e-37 127.3 0.0 3.1e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase IBR PF01485.16 EGO28085.1 - 1.9e-17 62.8 20.8 3.1e-09 36.5 5.1 2.5 2 0 0 2 2 2 2 IBR domain ABC_tran PF00005.22 EGO28089.1 - 3.4e-28 98.6 0.1 6.1e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO28089.1 - 0.00021 21.3 0.7 0.14 12.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGO28089.1 - 0.0021 18.0 0.0 0.0056 16.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO28089.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO28089.1 - 0.02 15.1 0.1 0.053 13.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EGO28089.1 - 0.028 13.6 2.0 0.49 9.5 0.1 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EGO28089.1 - 0.04 13.7 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EGO28089.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.6 1 1 1 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EGO28089.1 - 0.17 11.4 0.4 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ofd1_CTDD PF10637.4 EGO28090.1 - 2.7e-85 285.7 0.0 3.3e-79 265.7 0.0 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term AflR PF08493.5 EGO28092.1 - 0.38 9.7 2.7 2 7.3 0.0 2.3 2 0 0 2 2 2 0 Aflatoxin regulatory protein Polyoma_lg_T_C PF06431.6 EGO28095.1 - 0.088 11.4 1.5 0.11 11.1 1.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Nop14 PF04147.7 EGO28095.1 - 0.12 10.2 11.5 0.15 9.9 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family SR-25 PF10500.4 EGO28095.1 - 0.17 11.3 12.1 0.29 10.5 8.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3827 PF12877.2 EGO28095.1 - 0.21 9.6 4.8 0.26 9.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.9 EGO28095.1 - 0.27 9.2 12.7 0.34 8.8 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGO28095.1 - 0.4 9.9 12.7 0.049 12.9 6.4 1.3 2 0 0 2 2 2 0 SDA1 YL1 PF05764.8 EGO28095.1 - 6.2 6.3 18.7 1 8.9 10.6 1.4 2 0 0 2 2 2 0 YL1 nuclear protein Retrotrans_gag PF03732.12 EGO28098.1 - 1.1e-05 25.4 4.9 1.6e-05 24.8 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EGO28099.1 - 0.00014 22.2 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28099.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO28099.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Siva PF05458.7 EGO28099.1 - 0.081 12.4 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PepSY_TM_1 PF13172.1 EGO28100.1 - 5.2 6.9 7.9 2.4 8.0 3.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM helix COesterase PF00135.23 EGO28102.1 - 1.8e-09 36.8 0.0 1.8e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF1675 PF07897.6 EGO28103.1 - 6.5 6.5 14.0 9.2 6.0 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Borrelia_P83 PF05262.6 EGO28103.1 - 8.4 4.5 16.5 12 4.0 11.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1423 PF07227.6 EGO28103.1 - 9.1 4.8 16.1 13 4.3 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) HIG_1_N PF04588.8 EGO28104.1 - 0.027 14.2 2.7 0.071 12.8 1.9 1.8 1 1 0 1 1 1 0 Hypoxia induced protein conserved region Tom37_C PF11801.3 EGO28105.1 - 1.1 9.1 4.1 0.56 10.0 1.1 1.7 1 1 1 2 2 2 0 Tom37 C-terminal domain Nucleoporin2 PF04096.9 EGO28107.1 - 3.9e-42 143.3 0.0 5.6e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase RNA_pol_Rpb2_6 PF00562.23 EGO28108.1 - 1.2e-113 379.8 0.0 1.5e-113 379.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGO28108.1 - 6.5e-32 110.1 0.0 1e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EGO28108.1 - 7.9e-26 89.6 0.0 1.8e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EGO28108.1 - 7.8e-24 83.4 0.0 1.7e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EGO28108.1 - 6.4e-22 77.9 0.0 1.4e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGO28108.1 - 1.7e-18 66.6 0.1 3.2e-14 52.9 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EGO28108.1 - 0.029 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 zf-C2H2 PF00096.21 EGO28110.1 - 0.059 13.7 6.6 0.62 10.5 0.5 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type C1_4 PF07975.7 EGO28110.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_4 PF13894.1 EGO28110.1 - 0.71 10.3 6.3 1.6 9.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Methyltransf_23 PF13489.1 EGO28111.1 - 2.6e-12 46.7 0.0 4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO28111.1 - 7.6e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO28111.1 - 2.6e-07 30.3 0.0 4.7e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO28111.1 - 3.5e-07 30.6 0.0 7.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO28111.1 - 0.0037 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGO28111.1 - 0.0059 17.1 0.0 0.017 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO28111.1 - 0.031 14.6 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGO28111.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_m1G_MT PF01746.16 EGO28112.1 - 4.2e-29 101.4 0.1 2.3e-22 79.4 0.1 2.2 1 1 1 2 2 2 2 tRNA (Guanine-1)-methyltransferase Abhydrolase_2 PF02230.11 EGO28113.1 - 3.2e-56 190.1 0.0 1.1e-55 188.3 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGO28113.1 - 2.1e-10 40.5 0.1 3.3e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO28113.1 - 3.5e-08 33.6 0.9 6e-08 32.8 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGO28113.1 - 1.6e-05 24.4 0.0 3e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EGO28113.1 - 0.00031 20.4 0.0 0.0011 18.5 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO28113.1 - 0.019 14.1 0.0 5.3 6.1 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EGO28113.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioredoxin_4 PF13462.1 EGO28116.1 - 3.2e-09 37.0 0.0 1.2e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin PCRF PF03462.13 EGO28116.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PCRF domain STE3 PF02076.10 EGO28117.1 - 9.5e-51 172.5 19.8 6.7e-29 100.8 5.2 3.0 1 1 2 3 3 3 3 Pheromone A receptor LrgB PF04172.11 EGO28117.1 - 0.016 14.4 1.4 0.016 14.4 1.0 1.7 2 0 0 2 2 2 0 LrgB-like family Cyt-b5 PF00173.23 EGO28118.1 - 3.7e-22 77.9 0.0 4.7e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Macoilin PF09726.4 EGO28120.1 - 0.12 10.6 4.0 0.2 9.8 2.8 1.3 1 0 0 1 1 1 0 Transmembrane protein LAGLIDADG_3 PF14528.1 EGO28120.1 - 0.14 12.3 0.0 21 5.4 0.0 2.8 2 0 0 2 2 2 0 LAGLIDADG-like domain Spc24 PF08286.6 EGO28120.1 - 0.98 9.1 10.0 0.37 10.4 3.2 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 EGO28120.1 - 4.3 5.6 4.4 8.2 4.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EGO28120.1 - 7 6.1 17.6 0.054 13.0 4.1 2.6 3 0 0 3 3 3 0 IncA protein GatB_N PF02934.10 EGO28122.1 - 7.3e-108 359.8 0.0 9.1e-108 359.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGO28122.1 - 4.2e-30 104.4 0.0 6.5e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 GatB domain PAP_central PF04928.12 EGO28124.1 - 2.5e-105 350.9 0.0 3.1e-105 350.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EGO28124.1 - 2.9e-44 150.3 0.0 4.4e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGO28124.1 - 1.2e-09 38.3 0.0 3.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EGO28124.1 - 0.025 12.1 0.0 0.044 11.3 0.0 1.3 1 0 0 1 1 1 0 Nrap protein Beta_helix PF13229.1 EGO28125.1 - 7.8e-06 25.7 33.2 0.0046 16.7 15.5 3.2 1 1 1 2 2 2 2 Right handed beta helix region RRM_1 PF00076.17 EGO28126.1 - 9.5e-08 31.5 0.0 2.7e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO28126.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NAGLU PF05089.7 EGO28130.1 - 3.3e-126 420.5 6.0 4.4e-126 420.1 4.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EGO28130.1 - 2.8e-61 207.2 5.3 3.9e-61 206.7 3.2 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EGO28130.1 - 4.2e-05 23.1 0.0 0.00086 18.9 0.0 2.5 1 1 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Hist_deacetyl PF00850.14 EGO28131.1 - 4.8e-75 252.7 0.1 7.4e-75 252.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain HA2 PF04408.18 EGO28133.1 - 1.4e-22 79.6 0.0 3.6e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO28133.1 - 9.1e-16 57.7 0.0 2.8e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO28133.1 - 2.3e-10 40.1 0.0 7.1e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO28133.1 - 2.9e-08 33.4 0.3 9e-08 31.7 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO28133.1 - 0.00089 19.3 0.4 0.019 15.1 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGO28133.1 - 0.012 15.3 0.1 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EGO28133.1 - 0.018 14.9 0.0 2.6 7.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EGO28133.1 - 0.029 14.0 0.1 0.35 10.5 0.0 2.7 4 0 0 4 4 4 0 Archaeal ATPase T2SE PF00437.15 EGO28133.1 - 0.091 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Tyrosinase PF00264.15 EGO28134.1 - 1e-29 104.3 0.1 1.6e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NDUFA12 PF05071.11 EGO28136.1 - 1.4e-19 70.4 0.7 1.9e-19 70.0 0.5 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hydrophobin PF01185.13 EGO28137.1 - 8e-21 74.2 9.3 9.6e-21 74.0 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CMAS PF02353.15 EGO28138.1 - 2.7e-58 197.2 0.0 3.5e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGO28138.1 - 9e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO28138.1 - 5e-06 27.0 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO28138.1 - 2.5e-05 24.6 0.0 7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO28138.1 - 0.0095 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO28138.1 - 0.019 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EGO28138.1 - 0.024 15.4 1.1 0.4 11.5 0.0 3.1 5 0 0 5 5 3 0 Methyltransferase domain MTS PF05175.9 EGO28138.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO28138.1 - 0.033 14.6 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 EGO28138.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SAC3 PF12209.3 EGO28138.1 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain RasGAP_C PF03836.10 EGO28139.1 - 1.4e-40 138.2 2.8 3.8e-40 136.8 1.9 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EGO28139.1 - 6e-32 110.9 0.0 6e-32 110.9 0.0 2.8 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EGO28139.1 - 4.6e-21 72.3 62.1 0.03 13.9 1.1 13.4 13 0 0 13 13 13 10 IQ calmodulin-binding motif CH PF00307.26 EGO28139.1 - 6e-10 39.1 0.0 1.7e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.6 EGO28139.1 - 0.29 10.7 5.8 0.033 13.7 0.8 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 AA_permease PF00324.16 EGO28140.1 - 1e-111 373.6 45.9 1.2e-111 373.4 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO28140.1 - 5e-36 124.1 46.7 7.7e-36 123.5 32.4 1.2 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.6 EGO28140.1 - 0.24 10.9 2.4 0.74 9.3 1.7 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) NMO PF03060.10 EGO28141.1 - 3.9e-40 138.0 0.0 4.8e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO28141.1 - 0.019 13.8 0.6 0.95 8.2 0.2 2.2 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO28141.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase WD40 PF00400.27 EGO28142.1 - 1.7e-21 75.1 2.0 8.2e-10 38.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 EGO28142.1 - 0.0014 18.4 1.0 0.01 15.6 0.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO28142.1 - 0.0033 17.4 1.2 0.0089 16.0 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO28142.1 - 0.048 13.3 3.3 0.13 11.8 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGO28142.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.1 EGO28142.1 - 0.097 12.4 3.9 0.4 10.4 2.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.27 EGO28143.1 - 1.5e-15 56.3 4.6 5.4e-11 41.9 0.1 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nbas_N PF15492.1 EGO28143.1 - 0.072 12.1 0.0 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Tet_JBP PF12851.2 EGO28147.1 - 0.00012 21.4 0.5 0.00016 20.9 0.3 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily RVP_2 PF08284.6 EGO28148.1 - 7.9e-06 25.8 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO28148.1 - 0.001 19.5 0.0 0.0015 18.9 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28148.1 - 0.0039 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EGO28149.1 - 5.4e-07 29.2 4.4 5.4e-07 29.2 3.1 2.3 3 0 0 3 3 3 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28149.1 - 3.5e-06 26.9 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO28149.1 - 0.025 13.9 0.4 0.037 13.4 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO28149.1 - 8.7 6.1 17.2 0.26 11.0 3.6 2.9 2 1 1 3 3 3 0 Zinc knuckle zinc-ribbons_6 PF07191.7 EGO28150.1 - 0.029 14.1 1.2 7.5 6.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons Ras PF00071.17 EGO28153.1 - 1.4e-54 183.8 0.0 1.8e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO28153.1 - 1.9e-18 67.0 0.0 2.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO28153.1 - 7.1e-15 54.6 0.0 2.9e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO28153.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGO28153.1 - 8.8e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO28153.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGO28153.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF4219 PF13961.1 EGO28154.1 - 6.8e-06 25.3 0.1 1.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EGO28154.1 - 0.00032 20.2 0.0 0.00038 20.0 0.0 1.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type 3A PF00803.13 EGO28155.1 - 0.022 13.8 3.0 0.032 13.2 2.1 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family gag_pre-integrs PF13976.1 EGO28156.1 - 6.5e-11 41.7 0.7 1.1e-10 41.0 0.5 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain Retrotrans_gag PF03732.12 EGO28157.1 - 0.00044 20.2 1.6 0.0011 19.0 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein GARS_A PF01071.14 EGO28158.1 - 1.1e-77 259.9 0.0 1.8e-77 259.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EGO28158.1 - 3.8e-35 120.3 0.1 4.2e-34 116.9 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EGO28158.1 - 5.7e-32 110.8 0.0 1.9e-31 109.1 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGO28158.1 - 1.2e-27 95.8 0.2 3.5e-27 94.4 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EGO28158.1 - 2.6e-19 69.2 1.5 5.7e-18 64.9 0.5 3.2 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 EGO28158.1 - 2e-09 36.6 0.0 4.7e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EGO28158.1 - 2e-08 34.1 0.0 5.9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGO28158.1 - 0.00065 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain TraH_2 PF06871.6 EGO28158.1 - 0.0055 16.1 0.2 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 TraH_2 ATP-grasp_3 PF02655.9 EGO28158.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 EGO28158.1 - 0.088 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Cauli_VI PF01693.11 EGO28159.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin ER-remodelling PF14755.1 EGO28159.1 - 0.2 11.7 6.7 0.34 10.9 4.6 1.6 1 1 0 1 1 1 0 Intracellular membrane remodeller IDO PF01231.13 EGO28160.1 - 0.058 11.8 0.1 0.28 9.5 0.0 1.8 1 1 0 1 1 1 0 Indoleamine 2,3-dioxygenase Alpha_kinase PF02816.13 EGO28161.1 - 8e-06 25.6 0.0 9.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family PTCB-BRCT PF12738.2 EGO28163.1 - 0.2 11.5 1.9 6.2 6.7 0.0 3.2 3 0 0 3 3 3 0 twin BRCT domain DUF2718 PF10918.3 EGO28165.1 - 0.039 14.0 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) Cut8_M PF14483.1 EGO28167.1 - 0.014 15.1 1.6 0.03 14.1 1.1 1.5 1 0 0 1 1 1 0 Cut8 dimerisation domain DUF1043 PF06295.7 EGO28168.1 - 0.072 12.7 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Cgr1 PF03879.9 EGO28170.1 - 0.28 11.3 12.1 0.41 10.8 8.4 1.2 1 0 0 1 1 1 0 Cgr1 family DDE_3 PF13358.1 EGO28173.1 - 8e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4219 PF13961.1 EGO28174.1 - 0.0015 17.8 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) WEMBL PF05701.6 EGO28177.1 - 0.0038 15.7 0.1 0.0049 15.3 0.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF1664 PF07889.7 EGO28177.1 - 0.023 14.4 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Acyl_transf_3 PF01757.17 EGO28179.1 - 0.0084 14.9 1.2 0.01 14.7 0.9 1.2 1 0 0 1 1 1 1 Acyltransferase family RVP_2 PF08284.6 EGO28180.1 - 0.015 15.2 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Phenyl_P_gamma PF09662.5 EGO28180.1 - 0.071 12.8 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) SprB PF13573.1 EGO28180.1 - 1.5 8.4 4.7 7.4 6.2 3.2 2.0 1 1 0 1 1 1 0 SprB repeat RVP_2 PF08284.6 EGO28182.1 - 1.5e-07 31.4 0.0 1.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO28182.1 - 0.0011 18.7 0.0 0.0034 17.1 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO28182.1 - 0.0016 18.9 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF2034 PF10356.4 EGO28183.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DEAD PF00270.24 EGO28185.1 - 4.3e-11 42.5 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO28185.1 - 0.0046 16.7 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 EGO28186.1 - 1.6e-63 210.4 6.5 1.1e-22 79.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RasGEF PF00617.14 EGO28190.1 - 2.1e-28 99.3 0.0 4e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO28190.1 - 6.7e-12 45.4 0.0 2.7e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Miro PF08477.8 EGO28190.1 - 0.00014 22.3 0.0 0.00052 20.5 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGO28190.1 - 0.0019 17.6 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_17 PF13207.1 EGO28190.1 - 0.028 15.2 0.0 0.071 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGO28190.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EGO28190.1 - 0.13 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO28190.1 - 0.22 11.4 0.2 0.49 10.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGO28195.1 - 7.3e-56 188.5 0.0 1.3e-55 187.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO28195.1 - 8.2e-37 125.3 0.0 2e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO28195.1 - 6.3e-17 61.4 2.1 6.3e-17 61.4 1.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGO28195.1 - 0.00027 20.5 1.0 0.00088 18.8 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGO28195.1 - 0.0046 16.8 0.3 0.014 15.3 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Myb_DNA-bind_4 PF13837.1 EGO28196.1 - 2e-06 27.8 0.1 2.8e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF865 PF05906.6 EGO28196.1 - 0.13 11.8 0.2 0.37 10.4 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Fungal_trans PF04082.13 EGO28198.1 - 1.1e-05 24.4 0.1 2.8e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO28198.1 - 2e-05 24.3 6.7 3.6e-05 23.5 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AlkA_N PF06029.6 EGO28198.1 - 0.096 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 AlkA N-terminal domain KH_1 PF00013.24 EGO28200.1 - 3.7e-35 119.3 3.2 1.9e-09 37.0 0.0 6.6 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 EGO28200.1 - 7.2e-25 86.1 6.3 7.6e-07 28.6 0.1 6.4 7 0 0 7 7 7 4 KH domain DUF572 PF04502.8 EGO28204.1 - 0.61 9.2 14.1 1.2 8.3 9.8 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) UBN2_2 PF14227.1 EGO28205.1 - 9.3e-10 38.1 1.4 1.2e-09 37.7 0.9 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO28205.1 - 7.9e-09 35.3 0.5 1.1e-08 34.9 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGO28205.1 - 0.0015 18.0 0.2 0.002 17.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TPR_15 PF13429.1 EGO28205.1 - 0.034 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 EGO28205.1 - 0.066 12.3 0.1 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1018 PF06252.7 EGO28205.1 - 0.079 13.4 0.3 0.22 12.0 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) gag_pre-integrs PF13976.1 EGO28207.1 - 3.3e-11 42.6 0.1 5.3e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain DUF128 PF01995.11 EGO28209.1 - 0.036 12.9 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF128 Daxx PF03344.10 EGO28212.1 - 1.4 7.3 10.4 1.8 6.9 7.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF1414 PF07208.6 EGO28213.1 - 0.015 14.9 0.3 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) BTB PF00651.26 EGO28219.1 - 4.2e-05 23.4 0.0 8.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_8 PF01501.15 EGO28220.1 - 3.9e-28 98.4 0.0 5.8e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGO28220.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative RRF_GI PF12614.3 EGO28221.1 - 0.0065 16.2 0.6 0.014 15.2 0.4 1.5 1 0 0 1 1 1 1 Ribosome recycling factor Snapin_Pallidin PF14712.1 EGO28221.1 - 0.031 14.5 2.8 0.13 12.5 2.0 2.1 1 0 0 1 1 1 0 Snapin/Pallidin CDC37_N PF03234.9 EGO28221.1 - 0.047 14.0 0.4 0.11 12.8 0.1 1.7 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Tannase PF07519.6 EGO28222.1 - 0.035 12.8 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase AAA_15 PF13175.1 EGO28222.1 - 0.069 12.1 4.7 0.088 11.8 3.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain zf-CCHC PF00098.18 EGO28224.1 - 1.7e-06 27.7 0.4 3e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CHC2 PF01807.15 EGO28224.1 - 0.097 12.2 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CHC2 zinc finger RVP_2 PF08284.6 EGO28225.1 - 2e-05 24.5 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO28225.1 - 0.00017 21.3 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO28225.1 - 0.00025 21.4 0.0 0.00044 20.6 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease RapA_C PF12137.3 EGO28226.1 - 0.2 10.4 4.5 0.31 9.8 3.1 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Tho2 PF11262.3 EGO28227.1 - 0.0075 15.3 1.5 0.0081 15.2 1.1 1.0 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 PaaB PF06243.6 EGO28227.1 - 0.22 11.6 1.5 1.8 8.7 1.0 2.0 1 1 0 1 1 1 0 Phenylacetic acid degradation B DUF3886 PF13025.1 EGO28227.1 - 5.1 7.1 13.7 0.24 11.3 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) gag_pre-integrs PF13976.1 EGO28228.1 - 0.028 14.0 1.3 5.4 6.7 0.0 2.6 2 1 1 3 3 3 0 GAG-pre-integrase domain DUF2167 PF09935.4 EGO28229.1 - 0.041 12.6 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) DUF1192 PF06698.6 EGO28231.1 - 0.0076 16.0 0.9 0.015 15.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) HR1 PF02185.11 EGO28231.1 - 0.033 13.9 0.5 0.067 12.9 0.4 1.4 1 0 0 1 1 1 0 Hr1 repeat Unstab_antitox PF09720.5 EGO28231.1 - 0.04 13.6 0.3 0.072 12.7 0.2 1.3 1 0 0 1 1 1 0 Putative addiction module component ORC6 PF05460.8 EGO28231.1 - 2.4 7.1 8.2 3.1 6.7 5.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PIF1 PF05970.9 EGO28232.1 - 5.6e-07 28.8 0.1 6.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EGO28232.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO28232.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EGO28232.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.1 EGO28232.1 - 0.057 12.4 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain WEMBL PF05701.6 EGO28236.1 - 1.1 7.6 80.4 2.7 6.3 15.0 4.6 2 2 1 3 3 3 0 Weak chloroplast movement under blue light DUF1091 PF06477.8 EGO28240.1 - 0.013 15.9 0.1 5.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) HTH_OrfB_IS605 PF12323.3 EGO28240.1 - 0.042 13.1 0.1 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HEAT_2 PF13646.1 EGO28245.1 - 0.00022 21.4 0.8 1.9 8.8 0.2 3.7 3 1 1 4 4 4 3 HEAT repeats RIX1 PF08167.7 EGO28245.1 - 0.024 14.2 0.9 0.37 10.4 0.0 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 EGO28245.1 - 0.074 13.1 0.8 35 4.8 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EGO28245.1 - 0.41 11.1 3.5 13 6.3 0.1 4.5 4 1 1 5 5 5 0 HEAT-like repeat Arm PF00514.18 EGO28245.1 - 0.82 9.5 7.0 1 9.3 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Tet_JBP PF12851.2 EGO28246.1 - 0.0048 16.2 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Phage_30_8 PF06019.6 EGO28246.1 - 0.09 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage GP30.8 protein Nop14 PF04147.7 EGO28246.1 - 2 6.2 6.7 2.6 5.8 4.6 1.1 1 0 0 1 1 1 0 Nop14-like family STOP PF05217.7 EGO28248.1 - 0.1 12.2 4.6 0.24 11.0 3.3 1.5 1 1 1 2 2 2 0 STOP protein zf-CCHC PF00098.18 EGO28251.1 - 0.00012 21.7 1.5 0.00022 21.0 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28251.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein ProRS-C_1 PF09180.6 EGO28251.1 - 1.9 8.4 5.9 1.4 8.8 0.8 2.9 2 1 1 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DUF498 PF04430.9 EGO28253.1 - 0.026 14.0 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Retrotrans_gag PF03732.12 EGO28254.1 - 9.2e-07 28.8 0.0 9.2e-07 28.8 0.0 2.9 2 1 1 3 3 3 1 Retrotransposon gag protein FAM117 PF15388.1 EGO28255.1 - 0.14 11.4 5.7 0.18 10.9 3.9 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Phyto_Pns9_10 PF05878.6 EGO28255.1 - 0.32 9.9 5.5 0.44 9.5 3.8 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF2052 PF09747.4 EGO28255.1 - 4 7.3 16.8 5.9 6.7 11.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.9 EGO28255.1 - 5.3 4.9 11.7 6.8 4.5 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4219 PF13961.1 EGO28256.1 - 0.1 12.0 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Hepar_II_III PF07940.8 EGO28258.1 - 3.4e-08 33.4 0.1 6.6e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF3015 PF11220.3 EGO28261.1 - 0.014 14.9 0.4 0.021 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF1461 PF07314.6 EGO28266.1 - 0.043 13.5 0.2 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) vATP-synt_AC39 PF01992.11 EGO28266.1 - 0.087 11.9 0.2 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Consortin_C PF15281.1 EGO28266.1 - 0.092 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus FlgI PF02119.11 EGO28268.1 - 0.11 11.1 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar P-ring protein Olfactory_mark PF06554.7 EGO28269.1 - 0.0082 15.6 0.3 0.015 14.8 0.2 1.3 1 0 0 1 1 1 1 Olfactory marker protein MULE PF10551.4 EGO28269.1 - 0.037 14.1 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 MULE transposase domain Sec8_exocyst PF04048.9 EGO28272.1 - 1.9e-29 102.1 2.1 2.2e-29 101.9 0.1 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EGO28272.1 - 4.4e-08 32.3 0.3 2.4e-07 29.9 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EGO28272.1 - 0.0038 17.0 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) RVP_2 PF08284.6 EGO28273.1 - 0.088 12.7 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 EGO28275.1 - 0.024 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle C1_1 PF00130.17 EGO28275.1 - 5.5 6.8 8.9 0.48 10.1 0.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_1 PF03184.14 EGO28277.1 - 5.8e-12 45.2 0.1 8.3e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 EGO28279.1 - 3.5e-48 164.0 0.0 3.9e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28279.1 - 2.1e-16 59.7 0.0 2.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO28279.1 - 0.0043 16.0 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HTH_Tnp_Tc5 PF03221.11 EGO28280.1 - 2.7e-06 27.1 0.0 5.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3885 PF13021.1 EGO28283.1 - 0.029 14.0 1.2 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Retrotrans_gag PF03732.12 EGO28284.1 - 7.1e-07 29.2 0.7 1.1e-06 28.5 0.0 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein DASH_Hsk3 PF08227.6 EGO28284.1 - 0.059 13.5 0.1 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF664 PF04978.7 EGO28287.1 - 0.063 13.5 0.3 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF664) HATPase_c PF02518.21 EGO28288.1 - 0.0016 18.1 0.0 0.0061 16.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Urotensin_II PF02083.10 EGO28288.1 - 0.13 11.6 0.7 0.27 10.6 0.5 1.5 1 0 0 1 1 1 0 Urotensin II RVT_2 PF07727.9 EGO28291.1 - 9.7e-09 34.5 0.0 0.00066 18.7 0.0 2.0 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EGO28291.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.1 EGO28292.1 - 6.4e-08 32.5 0.0 3.1e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Frigida PF07899.6 EGO28294.1 - 0.024 13.4 1.4 0.037 12.7 0.9 1.2 1 0 0 1 1 1 0 Frigida-like protein DivIC PF04977.10 EGO28294.1 - 6.3 6.3 9.1 0.27 10.7 2.1 1.9 2 0 0 2 2 2 0 Septum formation initiator PA28_beta PF02252.13 EGO28296.1 - 5.5e-40 136.2 1.4 7.2e-40 135.8 1.0 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 EGO28296.1 - 7.7e-06 25.9 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Swi3 PF07962.7 EGO28296.1 - 0.047 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Ribosomal_L44 PF00935.14 EGO28298.1 - 0.24 11.4 3.0 0.25 11.3 2.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L44 Retrotrans_gag PF03732.12 EGO28299.1 - 3.9e-06 26.8 3.4 3.9e-06 26.8 2.4 3.1 2 2 1 3 3 3 1 Retrotransposon gag protein DNA_ligase_A_M PF01068.16 EGO28300.1 - 4.9e-62 208.8 0.0 8.1e-62 208.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO28300.1 - 1.6e-52 177.9 1.7 2.1e-52 177.4 0.3 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGO28300.1 - 1.9e-24 85.9 0.0 4.1e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EGO28300.1 - 0.0048 16.5 0.2 0.17 11.5 0.0 2.7 2 0 0 2 2 2 1 DNA ligase OB-like domain NIF PF03031.13 EGO28302.1 - 9.1e-24 83.9 0.0 7.4e-21 74.4 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EGO28302.1 - 2.8e-10 39.9 0.4 5e-09 35.8 0.1 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGO28302.1 - 1.3e-06 28.4 0.1 3.8e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3306 PF11748.3 EGO28304.1 - 0.26 11.9 2.9 0.33 11.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Retrotrans_gag PF03732.12 EGO28305.1 - 1.7e-05 24.7 0.1 5.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein PP-binding PF00550.20 EGO28307.1 - 9e-13 48.2 0.4 1.2e-12 47.9 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGO28307.1 - 7.9e-06 25.8 0.2 9.8e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EGO28307.1 - 0.022 14.8 0.1 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.4 EGO28307.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Ribosomal subunit 39S SPRY PF00622.23 EGO28308.1 - 1.2e-18 67.4 0.1 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Lectin_N PF03954.9 EGO28308.1 - 0.026 13.9 0.4 0.049 13.0 0.3 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DDE_1 PF03184.14 EGO28310.1 - 1.3e-39 135.5 0.1 1.8e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EGO28310.1 - 1.2e-06 28.2 0.0 5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Gb3_synth PF04572.7 EGO28314.1 - 0.092 12.4 5.8 2.4 7.8 1.5 2.6 1 1 1 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Tet_JBP PF12851.2 EGO28315.1 - 0.0044 16.3 0.0 0.0095 15.2 0.0 1.5 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily zf-CCHC PF00098.18 EGO28316.1 - 2.2e-05 24.1 2.1 2.2e-05 24.1 1.5 1.9 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28316.1 - 0.001 19.0 0.1 0.001 19.0 0.0 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein BMFP PF04380.8 EGO28316.1 - 0.043 13.9 0.5 1.6 8.8 0.2 2.9 3 0 0 3 3 3 0 Membrane fusogenic activity zf-CCHC_3 PF13917.1 EGO28316.1 - 0.068 12.9 3.7 0.16 11.7 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 EGO28317.1 - 9.1e-06 26.0 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28317.1 - 1.4e-05 24.7 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO28317.1 - 0.00051 19.9 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease PRANC PF09372.5 EGO28322.1 - 0.07 13.1 2.8 0.11 12.5 1.9 1.2 1 0 0 1 1 1 0 PRANC domain DUF966 PF06136.8 EGO28322.1 - 0.1 11.9 1.0 0.35 10.2 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF966) zf-C2H2_7 PF15269.1 EGO28322.1 - 3.5 7.5 5.3 2.6 7.9 0.6 2.6 1 1 1 2 2 2 0 Zinc-finger DUF89 PF01937.14 EGO28325.1 - 1.9e-108 362.4 0.1 2.3e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1965 PF09248.5 EGO28325.1 - 0.075 12.9 0.5 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Orthopox_A47 PF06334.6 EGO28326.1 - 0.084 11.9 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A47 protein Myb_DNA-bind_3 PF12776.2 EGO28328.1 - 0.00017 22.1 0.5 0.001 19.6 0.1 2.0 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO28328.1 - 0.013 15.6 0.2 0.086 12.9 0.0 2.1 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain gag-asp_proteas PF13975.1 EGO28329.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO28329.1 - 0.073 13.5 0.0 0.09 13.2 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease ADIP PF11559.3 EGO28332.1 - 0.088 12.7 5.1 0.15 11.9 0.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HTH_37 PF13744.1 EGO28332.1 - 0.16 11.8 1.4 0.46 10.3 1.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DIL PF01843.14 EGO28334.1 - 1e-19 70.3 0.7 2.2e-19 69.2 0.5 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 EGO28334.1 - 3.4e-09 36.9 0.0 1.1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO28334.1 - 1.3e-08 35.1 0.1 4.2e-06 27.1 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EGO28334.1 - 2.3e-08 33.4 0.1 0.0038 16.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGO28334.1 - 1.3e-05 25.2 0.6 8.6e-05 22.6 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO28334.1 - 0.0014 18.6 0.1 0.025 14.7 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat DnaA_N PF11638.3 EGO28335.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 DnaA N-terminal domain Retrotrans_gag PF03732.12 EGO28341.1 - 9.6e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EGO28342.1 - 0.0097 15.6 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO28342.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DHC_N1 PF08385.7 EGO28343.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF3591 PF12157.3 EGO28344.1 - 1.7e-67 227.8 1.4 1.7e-67 227.8 1.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EGO28344.1 - 5.9e-05 22.6 2.5 0.00012 21.6 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle SMN PF06003.7 EGO28344.1 - 0.00064 18.9 5.1 0.0009 18.4 0.3 2.2 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF1678 PF07913.6 EGO28346.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) GrpE PF01025.14 EGO28346.1 - 0.42 10.1 1.1 0.52 9.8 0.0 1.6 2 0 0 2 2 2 0 GrpE Axin_b-cat_bind PF08833.5 EGO28347.1 - 1.1 8.9 3.3 2.6 7.8 2.3 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain Tet_JBP PF12851.2 EGO28352.1 - 0.0001 21.6 0.0 0.0003 20.1 0.0 1.7 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily FlbT PF07378.6 EGO28352.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlbT Rubis-subs-bind PF09273.6 EGO28352.1 - 0.097 12.5 0.5 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding ORC6 PF05460.8 EGO28352.1 - 0.14 11.2 5.0 0.21 10.6 3.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Helicase_C PF00271.26 EGO28354.1 - 3.6e-16 58.7 0.0 7.6e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO28355.1 - 8.4e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EGO28355.1 - 7.3e-05 21.5 0.0 7.6e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Nucleocap_ssRNA PF11128.3 EGO28355.1 - 0.063 12.7 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid EF-hand_7 PF13499.1 EGO28356.1 - 9.8e-12 44.8 0.4 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO28356.1 - 2.4e-10 39.4 2.1 0.00021 20.9 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGO28356.1 - 3.9e-09 35.1 3.9 0.00014 20.9 0.2 3.9 4 0 0 4 4 4 2 EF hand DUF1456 PF07308.8 EGO28356.1 - 0.041 13.9 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_9 PF14658.1 EGO28356.1 - 0.081 12.8 0.0 3.3 7.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Slx4 PF09494.5 EGO28356.1 - 0.1 12.3 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Slx4 endonuclease EFhand_Ca_insen PF08726.5 EGO28356.1 - 0.12 12.3 0.0 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 EGO28356.1 - 0.49 9.8 5.2 0.15 11.4 0.6 2.3 2 1 0 2 2 2 0 EF hand WD40 PF00400.27 EGO28357.1 - 1e-26 91.7 7.9 1.4e-09 37.4 0.4 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGO28357.1 - 2.9e-17 62.3 0.0 8.5e-17 60.8 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex zf-CCHC PF00098.18 EGO28360.1 - 7.3e-07 28.8 3.2 2.7e-06 27.0 2.3 2.0 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO28360.1 - 0.021 14.2 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL55 protein HTH_38 PF13936.1 EGO28360.1 - 0.22 11.1 1.0 3.7 7.1 0.3 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain RVP_2 PF08284.6 EGO28361.1 - 2.2e-06 27.6 0.0 2.6e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO28361.1 - 2e-05 24.9 0.0 2.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28361.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RNA_pol_I_A49 PF06870.7 EGO28362.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor CCER1 PF15482.1 EGO28364.1 - 0.075 12.6 0.0 0.075 12.6 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 zf-CCHC_4 PF14392.1 EGO28365.1 - 0.023 14.3 2.0 0.043 13.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle UPF0121 PF03661.8 EGO28368.1 - 1.3e-20 73.6 3.9 2.1e-20 72.9 2.7 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Myb_DNA-bind_3 PF12776.2 EGO28370.1 - 5e-05 23.8 0.1 9.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO28370.1 - 0.005 16.9 0.4 0.012 15.6 0.3 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2635 PF10948.3 EGO28370.1 - 0.07 12.4 0.3 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Helicase_C PF00271.26 EGO28375.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF1654 PF07867.6 EGO28375.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DUF2051 PF09738.4 EGO28375.1 - 0.24 10.6 6.2 0.089 12.0 2.1 1.7 1 1 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Intg_mem_TP0381 PF09529.5 EGO28376.1 - 0.092 11.9 0.4 0.12 11.6 0.3 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DNA_pol_viral_C PF00336.13 EGO28377.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain WD40 PF00400.27 EGO28379.1 - 1.1e-69 228.0 19.9 1.3e-08 34.3 0.0 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.6 EGO28379.1 - 9.8e-38 128.9 0.0 1.5e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 EGO28379.1 - 5.6e-05 22.0 7.4 0.16 10.7 0.0 5.5 3 2 2 7 7 7 2 Nup133 N terminal like Nup160 PF11715.3 EGO28379.1 - 0.00053 18.2 3.1 1.1 7.3 0.3 4.0 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGO28379.1 - 0.025 12.8 0.7 1.3 7.2 0.0 3.4 3 1 1 4 4 4 0 Cytochrome D1 heme domain bZIP_1 PF00170.16 EGO28381.1 - 0.00013 21.8 2.1 0.00025 20.9 1.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EGO28381.1 - 0.12 11.9 0.2 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF357 PF04010.8 EGO28381.1 - 0.14 11.9 0.1 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) bZIP_2 PF07716.10 EGO28381.1 - 1.6 8.5 8.1 0.26 11.1 1.8 2.4 2 1 0 2 2 2 0 Basic region leucine zipper Ribosomal_L21e PF01157.13 EGO28382.1 - 0.051 13.3 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L21e WD40 PF00400.27 EGO28383.1 - 1e-11 44.2 2.3 1.3e-05 24.8 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 EGO28383.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal HMG_box PF00505.14 EGO28384.1 - 1.6e-14 53.9 0.1 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO28384.1 - 0.0069 16.7 0.4 0.017 15.4 0.3 1.7 1 1 0 1 1 1 1 HMG-box domain AalphaY_MDB PF04611.7 EGO28386.1 - 0.0046 16.8 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 Mating type protein A alpha Y mating type dependent binding region Ribosomal_S14 PF00253.16 EGO28387.1 - 0.016 14.5 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e DUF3681 PF12442.3 EGO28391.1 - 0.062 13.4 0.0 0.087 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) gag-asp_proteas PF13975.1 EGO28392.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease 2-oxoacid_dh PF00198.18 EGO28393.1 - 2.5e-79 265.7 0.0 3.6e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGO28393.1 - 8e-19 67.0 1.7 2e-18 65.7 0.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EGO28393.1 - 1.6e-13 50.0 0.1 3.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain gag-asp_proteas PF13975.1 EGO28394.1 - 0.031 14.0 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EGO28395.1 - 1.9e-07 30.6 5.6 3.6e-07 29.7 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28395.1 - 3.9e-07 30.0 0.6 3.9e-07 30.0 0.4 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.1 EGO28395.1 - 0.46 10.0 4.8 0.92 9.0 3.3 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EGO28396.1 - 3.6e-07 29.8 4.3 6e-07 29.0 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO28396.1 - 0.069 12.8 1.7 0.069 12.8 1.2 2.1 2 0 0 2 2 2 0 Zinc knuckle gag_pre-integrs PF13976.1 EGO28397.1 - 4.7e-11 42.1 0.3 8.5e-11 41.3 0.2 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_4 PF14392.1 EGO28398.1 - 0.029 14.0 2.0 0.05 13.2 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO28398.1 - 0.38 10.4 1.9 1 9.0 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO28398.1 - 2 8.2 8.6 4.4 7.1 6.0 1.5 1 0 0 1 1 1 0 CD24 protein Tet_JBP PF12851.2 EGO28399.1 - 0.00013 21.3 0.1 0.00039 19.7 0.0 1.6 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Hist_deacetyl PF00850.14 EGO28401.1 - 2.5e-81 273.3 0.0 4.1e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.5 EGO28401.1 - 0.037 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 NIL domain ORC6 PF05460.8 EGO28402.1 - 0.19 10.8 7.6 0.25 10.4 5.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DHC_N2 PF08393.8 EGO28404.1 - 0.085 11.3 2.0 0.11 11.0 1.4 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Imm42 PF15601.1 EGO28404.1 - 0.16 11.4 1.6 0.95 8.8 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 42 DDE_3 PF13358.1 EGO28405.1 - 1.1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease RED_N PF07808.8 EGO28407.1 - 0.027 13.6 0.4 0.032 13.4 0.3 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Sec2p PF06428.6 EGO28407.1 - 0.042 13.6 0.7 0.061 13.1 0.5 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p TPR_11 PF13414.1 EGO28409.1 - 1.5e-15 56.5 2.7 2.5e-15 55.8 1.9 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EGO28409.1 - 3e-12 45.6 0.5 2e-05 23.9 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO28409.1 - 8.8e-08 31.5 0.7 0.0029 17.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO28409.1 - 2.8e-05 24.6 1.0 6.3e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO28409.1 - 0.00038 20.0 0.5 0.45 10.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO28409.1 - 0.00055 19.8 0.6 0.27 11.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO28409.1 - 0.0013 18.3 0.1 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO28409.1 - 0.0059 16.7 0.9 0.011 15.8 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat OPT PF03169.10 EGO28410.1 - 5.7e-192 639.4 52.3 7e-192 639.1 36.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PRELI PF04707.9 EGO28411.1 - 9.5e-37 125.9 0.0 1.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family TauD PF02668.11 EGO28412.1 - 1.5e-49 169.0 0.4 1.8e-49 168.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.20 EGO28415.1 - 3.4e-65 219.7 0.0 6.4e-65 218.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28415.1 - 2.9e-37 128.1 0.0 5.7e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO28415.1 - 1.2e-06 27.7 0.0 5.1e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGO28415.1 - 0.0015 18.3 0.1 0.0088 15.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGO28415.1 - 0.0036 16.2 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 TGS PF02824.16 EGO28416.1 - 1.1e-20 73.2 0.0 1.7e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGO28416.1 - 1.3e-18 67.0 0.0 3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO28416.1 - 9.1e-11 41.2 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGO28416.1 - 0.001 19.5 0.1 0.0084 16.6 0.0 2.3 1 1 1 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EGO28416.1 - 0.0036 17.1 0.1 0.12 12.1 0.0 2.5 1 1 1 2 2 2 1 Dynamin family MCM PF00493.18 EGO28416.1 - 0.047 12.5 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family Lactamase_B_2 PF12706.2 EGO28417.1 - 3.4e-12 46.3 0.2 1.9e-11 43.8 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO28417.1 - 4.2e-12 46.1 0.2 8.5e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EGO28417.1 - 0.0086 15.7 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PRELI PF04707.9 EGO28418.1 - 1.4e-30 105.9 0.0 1.7e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family CDtoxinA PF03498.9 EGO28418.1 - 0.094 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family RIC1 PF07064.8 EGO28420.1 - 1.7e-75 253.7 0.4 2.7e-75 253.1 0.3 1.3 1 0 0 1 1 1 1 RIC1 PD40 PF07676.7 EGO28420.1 - 0.0031 17.1 0.0 0.17 11.6 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40 PF00400.27 EGO28420.1 - 0.0035 17.1 0.5 0.55 10.1 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Glyco_transf_28 PF03033.15 EGO28421.1 - 2.4e-26 92.1 0.0 5.3e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EGO28421.1 - 1.5e-21 75.6 4.9 3.4e-11 42.5 0.1 3.7 4 0 0 4 4 4 3 GRAM domain PH PF00169.24 EGO28421.1 - 4.2e-14 52.6 0.6 1.4e-11 44.4 0.1 3.1 3 0 0 3 3 3 1 PH domain UDPGT PF00201.13 EGO28421.1 - 7.9e-06 24.6 0.0 1.7e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.1 EGO28421.1 - 0.0013 18.7 0.0 0.0079 16.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EGO28421.1 - 0.0015 18.7 0.9 0.064 13.5 0.6 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain SUR7 PF06687.7 EGO28422.1 - 9.2e-17 61.3 12.4 1.1e-16 61.0 8.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EGO28422.1 - 1.1e-05 25.2 9.6 1.1e-05 25.2 6.7 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Retrotrans_gag PF03732.12 EGO28423.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein TIM21 PF08294.6 EGO28424.1 - 2.8e-23 82.1 0.0 2.1e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 TIM21 ATP-synt_F PF01990.12 EGO28425.1 - 1.7e-32 111.6 0.2 1.9e-32 111.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EGO28425.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase IFT46_B_C PF12317.3 EGO28425.1 - 0.041 13.2 0.1 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF1569 PF07606.6 EGO28425.1 - 0.075 12.9 0.0 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1569) SGT1 PF07093.6 EGO28426.1 - 2.1e-136 455.7 21.6 6.7e-135 450.7 15.0 2.0 1 1 0 1 1 1 1 SGT1 protein Helicase_C PF00271.26 EGO28427.1 - 0.0016 18.2 0.0 0.0093 15.8 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO28427.1 - 0.046 13.2 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Coat_F PF07875.7 EGO28427.1 - 0.11 12.6 0.1 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Coat F domain Clat_adaptor_s PF01217.15 EGO28428.1 - 1.9e-43 147.5 0.2 6.1e-43 145.9 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.9 EGO28429.1 - 5.9e-40 136.0 0.3 8.7e-40 135.5 0.2 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Nramp PF01566.13 EGO28430.1 - 5e-91 305.1 14.7 5e-91 305.1 10.2 1.9 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Catalase PF00199.14 EGO28431.1 - 3.7e-163 542.6 0.1 6.8e-163 541.8 0.0 1.5 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.7 EGO28431.1 - 1.7e-18 66.2 0.0 3.5e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EGO28431.1 - 4e-12 45.8 0.0 7.9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGO28431.1 - 0.00039 19.7 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DUF3666 PF12408.3 EGO28431.1 - 0.032 13.3 0.0 0.68 9.0 0.0 2.3 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase zf-C2H2 PF00096.21 EGO28432.1 - 1.2e-07 31.6 18.2 1.6e-05 24.9 0.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO28432.1 - 4.8e-06 26.5 13.6 0.0011 19.1 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO28432.1 - 0.0021 18.2 2.2 0.0021 18.2 1.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGO28432.1 - 0.0023 18.0 1.7 0.049 13.7 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Chalcone PF02431.10 EGO28435.1 - 1.1e-27 96.7 0.0 2.8e-27 95.4 0.0 1.6 1 1 0 1 1 1 1 Chalcone-flavanone isomerase DUF3437 PF11919.3 EGO28436.1 - 2.4e-30 104.1 0.0 7.2e-30 102.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EGO28436.1 - 4.1e-07 29.5 10.2 0.008 16.1 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EGO28436.1 - 1.7e-06 28.2 0.2 0.0017 18.5 0.0 4.8 5 1 0 5 5 5 1 HEAT repeats Arm PF00514.18 EGO28436.1 - 0.00086 19.0 1.4 2.9 7.8 0.0 4.6 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat UME PF08064.8 EGO28436.1 - 0.0018 18.2 0.2 0.04 13.8 0.0 3.3 3 0 0 3 3 3 1 UME (NUC010) domain HEAT_EZ PF13513.1 EGO28436.1 - 0.13 12.7 2.9 25 5.5 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat Methyltransf_26 PF13659.1 EGO28437.1 - 2.3e-10 40.5 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO28437.1 - 5.6e-08 32.3 0.0 8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGO28437.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGO28437.1 - 0.084 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EGO28437.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EGO28437.1 - 0.14 11.5 0.1 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase C2 PF00168.25 EGO28438.1 - 1.9e-74 245.5 1.4 9.5e-16 57.4 0.1 5.6 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EGO28438.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) p450 PF00067.17 EGO28439.1 - 8.4e-28 97.0 0.0 9.9e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 EGO28440.1 - 3.3e-22 77.9 0.1 7.5e-07 28.7 0.0 5.1 5 0 0 5 5 5 5 Mitochondrial carrier protein NmrA PF05368.8 EGO28441.1 - 5.4e-20 71.6 0.0 7e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO28441.1 - 1.7e-09 37.9 0.5 3e-09 37.1 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO28441.1 - 1.4e-05 24.6 0.0 0.0041 16.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.1 EGO28441.1 - 0.004 16.5 0.1 0.0073 15.6 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein RmlD_sub_bind PF04321.12 EGO28441.1 - 0.0072 15.2 0.1 0.077 11.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EGO28441.1 - 0.015 15.2 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase CPSase_L_chain PF00289.17 EGO28441.1 - 0.07 13.2 0.0 0.31 11.1 0.0 2.0 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NmrA PF05368.8 EGO28442.1 - 3.3e-18 65.7 0.0 4.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO28442.1 - 1.2e-10 41.6 0.4 2e-09 37.6 0.2 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO28442.1 - 0.00042 19.8 0.0 0.0031 16.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO28442.1 - 0.0012 18.8 0.4 0.0019 18.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGO28442.1 - 0.0021 16.9 0.1 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain CPSase_L_chain PF00289.17 EGO28442.1 - 0.048 13.7 0.2 0.33 11.0 0.1 2.4 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Borrelia_P13 PF05628.7 EGO28443.1 - 0.13 12.0 2.7 0.14 11.9 0.6 2.0 1 1 1 2 2 2 0 Borrelia membrane protein P13 Las1 PF04031.8 EGO28444.1 - 6.1e-46 155.8 0.2 1.4e-45 154.6 0.1 1.7 1 0 0 1 1 1 1 Las1-like DUF500 PF04366.7 EGO28445.1 - 3.4e-38 129.9 0.6 5.6e-38 129.2 0.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EGO28445.1 - 1.2e-16 59.8 0.1 2.7e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO28445.1 - 1.6e-14 53.1 0.1 8.4e-14 50.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGO28445.1 - 4.1e-12 45.4 0.1 5.7e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.3 EGO28445.1 - 0.17 11.2 0.1 0.33 10.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) PIF1 PF05970.9 EGO28447.1 - 0.032 13.1 0.0 0.05 12.5 0.0 1.4 1 1 1 2 2 2 0 PIF1-like helicase PIF1 PF05970.9 EGO28449.1 - 0.095 11.6 0.0 0.095 11.6 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase RhoGAP PF00620.22 EGO28450.1 - 3.9e-41 140.1 0.0 1.3e-40 138.5 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EGO28450.1 - 1.1e-07 31.9 0.4 1.1e-07 31.9 0.3 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain PhaC_N PF07167.8 EGO28450.1 - 0.11 11.9 0.8 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus HAD_2 PF13419.1 EGO28452.1 - 9.5e-22 78.0 0.0 1.2e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO28452.1 - 3.7e-13 48.9 0.1 1.6e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO28452.1 - 7.4e-12 46.1 0.0 3e-10 40.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO28452.1 - 0.00017 21.7 0.0 0.00035 20.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGO28452.1 - 0.092 12.6 0.0 0.68 9.8 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GHMP_kinases_N PF00288.21 EGO28453.1 - 2e-12 47.0 0.1 3.9e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO28453.1 - 0.0018 18.4 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Dynein_heavy PF03028.10 EGO28454.1 - 4.1e-181 603.5 0.1 1e-180 602.2 0.0 1.6 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EGO28454.1 - 3.5e-126 421.0 6.0 3.5e-126 421.0 4.2 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EGO28454.1 - 3.7e-77 258.9 0.0 1.3e-76 257.2 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EGO28454.1 - 1.1e-44 152.0 0.1 5.3e-44 149.7 0.0 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EGO28454.1 - 2.2e-44 151.4 0.2 3.9e-43 147.3 0.1 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EGO28454.1 - 1.4e-39 135.8 5.9 2.5e-39 135.0 4.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EGO28454.1 - 9e-28 96.7 0.0 3.7e-12 46.1 0.0 6.2 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EGO28454.1 - 8.9e-21 74.1 0.0 4.1e-20 71.9 0.0 2.2 3 0 0 3 3 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EGO28454.1 - 2.2e-12 47.2 0.0 0.021 14.9 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EGO28454.1 - 6.1e-12 45.6 0.1 0.16 11.8 0.0 5.7 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 EGO28454.1 - 1.4e-11 44.7 0.2 0.016 15.4 0.0 4.8 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO28454.1 - 9.7e-08 32.8 0.8 0.15 12.9 0.0 6.0 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.1 EGO28454.1 - 1.4e-07 31.7 5.4 0.19 11.6 0.1 5.9 5 1 0 6 6 5 2 AAA ATPase domain AAA_18 PF13238.1 EGO28454.1 - 2.8e-07 30.8 2.6 0.05 13.9 0.0 6.4 6 0 0 6 6 6 1 AAA domain AAA_19 PF13245.1 EGO28454.1 - 1.9e-06 27.4 0.1 0.89 9.3 0.0 4.7 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 EGO28454.1 - 3.1e-06 27.0 0.0 0.66 9.8 0.0 5.1 6 0 0 6 6 4 2 AAA domain FtsK_SpoIIIE PF01580.13 EGO28454.1 - 3.8e-06 26.5 0.0 0.2 11.1 0.0 4.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family T2SE PF00437.15 EGO28454.1 - 4.9e-06 25.6 0.0 0.06 12.2 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein Mg_chelatase PF01078.16 EGO28454.1 - 1.1e-05 24.6 0.4 0.51 9.4 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EGO28454.1 - 0.00025 20.5 0.0 0.71 9.4 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGO28454.1 - 0.0015 17.6 1.1 2.4 7.2 0.0 4.6 5 0 0 5 5 5 1 Zeta toxin IstB_IS21 PF01695.12 EGO28454.1 - 0.0017 17.8 1.0 0.38 10.1 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_tran PF00005.22 EGO28454.1 - 0.0018 18.5 0.0 8 6.7 0.0 4.3 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.17 EGO28454.1 - 0.015 15.4 0.0 61 3.8 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 EGO28454.1 - 0.019 14.3 0.6 2.2 7.6 0.0 3.9 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 EGO28454.1 - 0.021 14.3 0.4 7.1 6.1 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EGO28454.1 - 0.022 14.6 1.2 3.3 7.4 0.0 4.1 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit MobB PF03205.9 EGO28454.1 - 0.066 12.9 0.1 25 4.5 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF972 PF06156.8 EGO28454.1 - 0.46 10.8 20.8 6.2 7.2 2.5 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) PLRV_ORF5 PF01690.12 EGO28454.1 - 1.2 8.1 0.9 2.3 7.2 0.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AAA_11 PF13086.1 EGO28454.1 - 1.6 8.2 9.3 3.6 7.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain IFT46_B_C PF12317.3 EGO28454.1 - 3.3 7.0 13.5 0.64 9.3 0.0 3.5 4 0 0 4 4 3 0 Intraflagellar transport complex B protein 46 C terminal APG6 PF04111.7 EGO28454.1 - 5 6.0 19.7 2.5 7.0 3.3 2.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EGO28454.1 - 5.8 6.0 8.6 0.26 10.4 0.5 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Phlebovirus_NSM PF07246.6 EGO28454.1 - 8 5.5 10.5 0.053 12.6 0.4 2.2 2 0 0 2 2 1 0 Phlebovirus nonstructural protein NS-M FliJ PF02050.11 EGO28455.1 - 0.0099 15.9 0.9 0.012 15.6 0.6 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein DUF4140 PF13600.1 EGO28455.1 - 0.083 13.3 0.3 0.084 13.3 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Vac_Fusion PF02346.11 EGO28455.1 - 0.1 11.9 0.4 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Peptidase_U4 PF03419.8 EGO28456.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Romo1 PF10247.4 EGO28461.1 - 1.5e-24 85.9 8.2 2e-24 85.5 5.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF2955 PF11168.3 EGO28461.1 - 0.099 12.3 0.8 0.16 11.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) L51_S25_CI-B8 PF05047.11 EGO28462.1 - 4.4e-10 39.1 0.0 7.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MFS_1 PF07690.11 EGO28463.1 - 1.1e-42 146.0 35.0 3.3e-28 98.4 7.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily H2TH PF06831.9 EGO28464.1 - 3.8e-22 77.8 0.0 5.8e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EGO28464.1 - 1.9e-07 31.4 0.0 4.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 EGO28464.1 - 0.0026 16.3 0.0 0.0038 15.8 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.17 EGO28464.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Beta-lactamase PF00144.19 EGO28465.1 - 3.1e-39 134.9 0.0 4.2e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EGO28465.1 - 0.12 12.2 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) HATPase_c PF02518.21 EGO28466.1 - 3.9e-26 90.9 0.0 8.6e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO28466.1 - 1.5e-18 66.7 0.0 1.6e-17 63.4 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGO28466.1 - 1.2e-16 60.4 0.3 1.5e-15 56.9 0.0 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EGO28466.1 - 1.4e-14 54.5 0.4 1.1e-13 51.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 EGO28466.1 - 3e-09 37.5 0.0 7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGO28466.1 - 2.2e-07 31.0 0.0 5.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EGO28466.1 - 1.2e-06 27.8 0.0 3.3e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain NACHT PF05729.7 EGO28466.1 - 0.0003 20.5 2.7 0.32 10.6 0.1 3.4 3 0 0 3 3 3 2 NACHT domain DUF815 PF05673.8 EGO28466.1 - 0.017 14.0 0.0 0.043 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TPR_11 PF13414.1 EGO28466.1 - 0.032 13.8 4.2 0.25 11.0 0.1 3.6 3 0 0 3 3 3 0 TPR repeat AAA_22 PF13401.1 EGO28466.1 - 0.032 14.3 0.2 0.5 10.5 0.1 3.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO28466.1 - 0.062 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF929 PF06053.6 EGO28466.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ArgK PF03308.11 EGO28466.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein TPR_12 PF13424.1 EGO28466.1 - 0.33 10.9 8.5 0.25 11.3 0.1 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.24 EGO28467.1 - 1.7e-36 125.2 0.1 3.3e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO28467.1 - 2e-25 88.4 0.0 7.8e-24 83.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO28467.1 - 0.00014 21.7 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Retrotrans_gag PF03732.12 EGO28468.1 - 7.4e-09 35.5 0.3 7.4e-09 35.5 0.2 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO28468.1 - 1.5e-06 27.8 1.4 2.8e-06 26.9 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Mito_carr PF00153.22 EGO28470.1 - 3.4e-53 177.3 0.4 4.5e-18 64.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.9 EGO28471.1 - 2.5e-12 46.4 4.3 4.4e-12 45.6 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EGO28471.1 - 0.0059 16.7 5.0 0.0059 16.7 3.5 2.6 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) DEAD PF00270.24 EGO28473.1 - 1e-38 132.4 0.0 2.5e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO28473.1 - 7.9e-23 80.1 0.0 1.6e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO28473.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGO28473.1 - 0.21 9.9 0.0 1.6 7.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EGO28473.1 - 0.41 10.8 1.6 2.9 8.0 1.1 2.2 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 EGO28474.1 - 2.3e-15 56.6 1.9 2.8e-15 56.3 1.3 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO28474.1 - 1.9e-06 28.1 0.6 2.2e-06 27.9 0.4 1.1 1 0 0 1 1 1 1 HMG-box domain Peptidase_M61 PF05299.7 EGO28474.1 - 0.021 14.7 0.1 0.024 14.5 0.1 1.0 1 0 0 1 1 1 0 M61 glycyl aminopeptidase RyR PF02026.11 EGO28474.1 - 0.14 12.1 0.7 0.19 11.7 0.5 1.1 1 0 0 1 1 1 0 RyR domain PolyA_pol PF01743.15 EGO28476.1 - 5.3e-26 91.3 0.1 1e-25 90.3 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGO28476.1 - 1.5e-06 27.6 0.1 3.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Arm PF00514.18 EGO28477.1 - 9.8e-66 215.5 30.1 6.4e-13 48.0 0.1 11.7 10 2 2 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGO28477.1 - 1.1e-24 86.5 10.3 1.2e-05 25.5 0.1 7.4 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 EGO28477.1 - 1.1e-17 62.4 17.1 0.28 11.3 0.0 10.1 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 EGO28477.1 - 4.7e-15 55.5 12.8 0.0044 17.4 0.1 8.4 5 2 4 9 9 9 4 HEAT-like repeat Arm_2 PF04826.8 EGO28477.1 - 5.3e-11 42.1 10.6 8.8e-07 28.2 1.3 3.2 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.15 EGO28477.1 - 6.9e-11 41.1 11.3 1.6e-07 30.0 0.1 2.7 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 EGO28477.1 - 1.1e-09 36.8 1.6 1.5e-09 36.3 1.1 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EGO28477.1 - 7e-07 28.6 10.0 0.0023 17.1 0.2 4.3 1 1 2 4 4 4 3 V-ATPase subunit H HEAT_PBS PF03130.11 EGO28477.1 - 0.013 15.9 10.1 47 4.8 0.1 7.3 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat DUF2454 PF10521.4 EGO28477.1 - 0.016 14.2 1.4 0.26 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 EGO28477.1 - 0.028 14.7 0.1 10 6.5 0.0 3.4 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EGO28477.1 - 0.054 13.4 4.4 20 5.1 0.0 4.1 2 1 3 5 5 5 0 V-ATPase subunit H DUF3361 PF11841.3 EGO28477.1 - 0.18 11.5 6.0 3.9 7.1 0.5 3.8 2 2 0 3 3 3 0 Domain of unknown function (DUF3361) Glyco_hydro_16 PF00722.16 EGO28478.1 - 3.7e-07 29.6 0.2 1.1e-06 28.0 0.0 1.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 BAG PF02179.11 EGO28479.1 - 0.00018 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 BAG domain Acatn PF13000.2 EGO28480.1 - 9.7e-128 427.0 28.1 2.6e-62 211.1 10.6 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.17 EGO28481.1 - 6.3e-62 209.6 0.0 8.2e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KH_2 PF07650.12 EGO28481.1 - 0.057 12.9 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 KH domain DUF1819 PF08849.6 EGO28481.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) PAS_10 PF13596.1 EGO28481.1 - 0.18 12.0 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain NAP PF00956.13 EGO28482.1 - 8.9e-31 106.8 9.1 2.7e-30 105.2 6.3 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EGO28482.1 - 7 6.8 15.2 0.15 12.2 3.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Syja_N PF02383.13 EGO28483.1 - 1.1e-85 287.1 0.0 2.1e-85 286.3 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain TAP42 PF04177.7 EGO28483.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 TAP42-like family DUF997 PF06196.7 EGO28483.1 - 0.42 10.1 4.9 0.79 9.2 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) LRR_9 PF14580.1 EGO28484.1 - 2.4e-59 199.8 0.1 4.3e-59 198.9 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EGO28484.1 - 1.9e-12 46.4 9.1 1.9e-07 30.5 1.1 3.8 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO28484.1 - 5.1e-10 38.9 9.3 3.6e-06 26.6 2.4 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 EGO28484.1 - 9.3e-05 22.0 5.2 3.3 8.3 0.4 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EGO28484.1 - 9.5e-05 22.0 2.1 0.21 11.7 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 EGO28484.1 - 0.0001 21.8 6.2 0.72 10.1 0.5 4.8 5 1 0 5 5 5 1 Leucine Rich Repeat MitMem_reg PF13012.1 EGO28485.1 - 9.1e-19 67.6 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGO28485.1 - 4e-11 42.6 0.0 7.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ric8 PF10165.4 EGO28485.1 - 0.081 11.7 0.1 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn MCM PF00493.18 EGO28486.1 - 5.7e-142 472.3 0.0 7.3e-142 472.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO28486.1 - 7.7e-20 71.5 0.1 2e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO28486.1 - 8.5e-07 28.3 0.0 0.00024 20.3 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO28486.1 - 9.7e-05 22.1 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGO28486.1 - 0.00029 20.4 0.1 0.0029 17.2 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EGO28486.1 - 0.0069 16.7 0.3 0.047 14.0 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 EGO28486.1 - 0.065 13.4 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-CCHC PF00098.18 EGO28487.1 - 2.7e-08 33.3 5.1 4.8e-08 32.5 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28487.1 - 4.2e-08 33.1 5.7 9.8e-08 31.9 3.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO28487.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO28487.1 - 0.89 9.3 6.3 0.64 9.8 3.0 1.7 1 1 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EGO28488.1 - 5.5e-26 91.0 0.0 7.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO28488.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EGO28488.1 - 0.089 12.6 0.4 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain NmrA PF05368.8 EGO28489.1 - 1.8e-17 63.3 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO28489.1 - 3.3e-09 36.9 0.1 1.9e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO28489.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO28489.1 - 0.073 12.9 0.4 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase SNAPc19 PF15497.1 EGO28490.1 - 0.1 12.8 0.7 0.1 12.8 0.5 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 BPL_LplA_LipB PF03099.14 EGO28491.1 - 3.6e-08 33.4 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ATP11 PF06644.6 EGO28492.1 - 5.4e-59 199.8 0.0 6.6e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein Ammonium_transp PF00909.16 EGO28494.1 - 1.7e-115 385.6 24.1 2e-115 385.4 16.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GtrA PF04138.9 EGO28494.1 - 8.7 6.3 24.2 0.02 14.8 2.2 3.8 3 1 1 4 4 4 0 GtrA-like protein Prenylcys_lyase PF07156.9 EGO28495.1 - 7.2e-44 150.1 0.0 1.3e-43 149.3 0.0 1.3 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EGO28495.1 - 8.8e-10 38.4 0.0 2.8e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGO28495.1 - 2.3e-09 36.8 0.1 6.4e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EGO28495.1 - 1e-06 27.9 1.8 7.9e-06 25.0 1.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO28495.1 - 1.1e-05 25.5 0.2 0.041 13.9 0.0 2.8 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO28495.1 - 0.0015 18.3 0.0 0.083 12.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO28495.1 - 0.046 13.5 0.1 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO28495.1 - 0.076 12.0 0.1 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EGO28495.1 - 0.08 13.3 0.3 13 6.2 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Orbi_VP7 PF00897.12 EGO28495.1 - 0.16 10.8 0.1 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 F-box PF00646.28 EGO28496.1 - 0.00073 19.1 0.3 0.0039 16.7 0.0 2.4 2 1 1 3 3 3 1 F-box domain F-box-like PF12937.2 EGO28496.1 - 0.007 16.0 0.7 0.017 14.8 0.5 1.6 1 0 0 1 1 1 1 F-box-like NUDIX PF00293.23 EGO28497.1 - 1.3e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF3329 PF11808.3 EGO28499.1 - 0.063 13.3 0.1 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) PepSY_TM_1 PF13172.1 EGO28499.1 - 1.4 8.7 4.9 1.5 8.7 2.6 1.7 1 1 0 1 1 1 0 PepSY-associated TM helix FlxA PF14282.1 EGO28501.1 - 0.025 14.5 0.2 0.03 14.2 0.1 1.1 1 0 0 1 1 1 0 FlxA-like protein Saw1 PF11561.3 EGO28501.1 - 0.027 13.8 0.0 0.032 13.6 0.0 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Myb_DNA-bind_3 PF12776.2 EGO28503.1 - 3.6e-07 30.7 0.1 4.5e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NUDIX PF00293.23 EGO28505.1 - 1.3e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.10 EGO28506.1 - 9.1e-97 323.8 0.0 1.2e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EGO28506.1 - 1.2e-60 203.4 0.0 2e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EGO28506.1 - 5.2e-07 29.8 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.10 EGO28507.1 - 1.7e-08 34.1 11.1 5.9e-08 32.4 7.6 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EGO28507.1 - 1.4e-05 24.9 8.9 3.3e-05 23.7 6.1 1.6 1 1 0 1 1 1 1 bZIP transcription factor DUF2216 PF10226.4 EGO28507.1 - 0.0014 18.1 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) bZIP_Maf PF03131.12 EGO28507.1 - 0.039 14.2 3.2 0.078 13.2 2.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PAT1 PF09770.4 EGO28507.1 - 0.38 8.9 16.0 0.5 8.5 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CHCH PF06747.8 EGO28508.1 - 6.1e-08 32.3 1.8 1.2e-07 31.3 1.1 1.6 1 1 1 2 2 2 1 CHCH domain Pet191_N PF10203.4 EGO28508.1 - 0.013 15.5 0.7 0.02 14.9 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EGO28508.1 - 0.034 14.1 0.5 0.054 13.5 0.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.8 EGO28508.1 - 0.043 13.2 0.4 0.059 12.8 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.7 EGO28508.1 - 0.19 11.6 0.9 7.5 6.4 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) GDPD PF03009.12 EGO28511.1 - 5.5e-33 114.5 0.0 7.2e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EGO28511.1 - 0.01 15.9 0.4 0.029 14.5 0.3 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UCR_TM PF02921.9 EGO28512.1 - 2.3e-18 66.1 1.3 4.6e-18 65.1 0.9 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EGO28512.1 - 1.4e-16 59.8 0.1 2.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase PF00069.20 EGO28513.1 - 6.6e-49 166.3 0.0 2.3e-48 164.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28513.1 - 4.9e-35 120.8 0.0 5e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO28513.1 - 0.0062 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF605 PF04652.11 EGO28513.1 - 9.3 5.5 18.3 15 4.8 12.7 1.4 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EGO28514.1 - 9.3e-43 146.2 0.0 1.5e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28514.1 - 2.6e-11 43.1 0.0 6.5e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF605 PF04652.11 EGO28514.1 - 0.00037 20.0 1.3 0.0004 19.8 0.9 1.1 1 0 0 1 1 1 1 Vta1 like Pox_ser-thr_kin PF05445.6 EGO28514.1 - 0.03 13.1 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase F-box-like PF12937.2 EGO28515.1 - 0.0045 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO28515.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain p450 PF00067.17 EGO28516.1 - 9.4e-58 195.8 0.0 2.2e-56 191.3 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 SprT-like PF10263.4 EGO28517.1 - 1e-18 67.4 1.0 1.3e-18 67.1 0.7 1.1 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EGO28517.1 - 0.011 15.7 2.5 0.019 14.9 1.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Copper-fist PF00649.13 EGO28519.1 - 3.4e-20 70.9 1.1 3.4e-20 70.9 0.8 3.0 4 0 0 4 4 4 1 Copper fist DNA binding domain Glyco_hydro_72 PF03198.9 EGO28520.1 - 1.6e-92 309.8 0.2 2.4e-92 309.3 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGO28520.1 - 6e-16 58.7 0.5 2e-15 57.0 0.4 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EGO28520.1 - 0.027 13.6 0.0 0.055 12.6 0.0 1.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ABC_membrane PF00664.18 EGO28521.1 - 5.6e-41 140.7 25.6 7.9e-22 77.9 2.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EGO28521.1 - 2.8e-39 134.5 8.8 1.2e-25 90.3 0.1 3.4 4 1 0 4 4 2 2 ABC transporter SMC_N PF02463.14 EGO28521.1 - 3e-11 42.9 5.5 0.00082 18.6 0.2 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO28521.1 - 6.4e-09 36.1 4.0 0.054 13.4 0.0 4.6 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EGO28521.1 - 5.5e-07 29.1 0.0 0.0088 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO28521.1 - 1.6e-05 24.3 0.2 0.048 13.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO28521.1 - 3e-05 24.4 1.7 0.00067 20.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO28521.1 - 3.3e-05 23.4 0.5 0.3 10.5 0.0 2.6 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 EGO28521.1 - 4.6e-05 23.4 1.0 0.1 12.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EGO28521.1 - 6.2e-05 22.0 0.0 0.074 11.9 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 EGO28521.1 - 0.00027 19.7 0.0 0.0023 16.6 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_17 PF13207.1 EGO28521.1 - 0.00062 20.5 0.1 2.2 9.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EGO28521.1 - 0.00069 19.7 0.4 2 8.5 0.1 3.0 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EGO28521.1 - 0.00075 19.9 0.1 1.8 9.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EGO28521.1 - 0.0013 18.4 0.2 2.1 8.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EGO28521.1 - 0.0025 17.0 0.1 1.4 8.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EGO28521.1 - 0.0026 16.8 0.0 0.56 9.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EGO28521.1 - 0.0059 16.4 6.1 0.073 12.8 0.2 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 ResIII PF04851.10 EGO28521.1 - 0.0082 15.9 0.3 1.1 9.1 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 EGO28521.1 - 0.009 15.9 1.4 1 9.3 0.1 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EGO28521.1 - 0.0091 16.3 1.0 3.5 7.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGO28521.1 - 0.011 15.1 1.0 3.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EGO28521.1 - 0.028 14.1 0.0 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase Pox_A32 PF04665.7 EGO28521.1 - 0.033 13.5 0.4 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 EGO28521.1 - 0.034 13.5 0.0 6.7 6.0 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 EGO28521.1 - 0.12 12.0 0.6 12 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EGO28521.1 - 0.13 12.4 0.9 2.4 8.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EGO28521.1 - 1.3 8.8 8.1 1.6 8.5 0.0 2.9 3 0 0 3 3 2 0 Dynamin family WD40 PF00400.27 EGO28522.1 - 1.3e-38 129.5 7.9 8.9e-10 38.0 0.1 7.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EGO28522.1 - 6.1e-08 31.2 2.1 0.00069 17.8 0.0 3.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 DivIC PF04977.10 EGO28522.1 - 0.62 9.5 3.0 1.3 8.5 2.1 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EGO28522.1 - 3.5 7.1 9.1 6 6.4 6.3 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EGO28522.1 - 6 5.8 7.5 9.2 5.2 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BC10 PF06726.7 EGO28523.1 - 8.8e-10 38.4 11.3 1.6e-09 37.6 7.9 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 CS PF04969.11 EGO28524.1 - 0.00011 22.7 0.1 0.00024 21.5 0.0 1.6 1 1 0 1 1 1 1 CS domain Sporozoite_P67 PF05642.6 EGO28524.1 - 0.4 8.5 10.5 0.5 8.1 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fork_head_N PF08430.7 EGO28524.1 - 1.1 9.6 22.2 1.6 9.0 15.4 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region p450 PF00067.17 EGO28525.1 - 1e-52 179.2 0.0 1.4e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Apolipoprotein PF01442.13 EGO28526.1 - 5.6e-05 22.7 1.9 6.5e-05 22.5 1.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGO28526.1 - 0.00056 20.2 8.9 0.0013 19.0 1.0 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) LEA_1 PF03760.10 EGO28526.1 - 0.0033 17.5 20.2 0.071 13.2 6.6 2.4 2 0 0 2 2 2 2 Late embryogenesis abundant (LEA) group 1 tRNA-synt_1e PF01406.14 EGO28526.1 - 0.0085 15.2 0.5 0.0092 15.1 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain LEA_4 PF02987.11 EGO28526.1 - 0.02 14.7 9.3 0.02 14.7 6.5 3.5 1 1 3 4 4 4 0 Late embryogenesis abundant protein YtxH PF12732.2 EGO28526.1 - 0.02 15.2 15.2 0.12 12.7 1.6 2.5 1 1 1 2 2 2 0 YtxH-like protein ISG65-75 PF11727.3 EGO28526.1 - 0.068 12.2 8.4 0.083 11.9 5.8 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein HisKA_3 PF07730.8 EGO28526.1 - 0.069 13.5 2.9 0.58 10.5 0.9 2.3 1 1 1 2 2 2 0 Histidine kinase Cas_CT1975 PF09344.5 EGO28526.1 - 0.2 11.0 7.2 0.25 10.6 5.0 1.0 1 0 0 1 1 1 0 CT1975-like protein Prominin PF05478.6 EGO28526.1 - 0.28 8.6 1.2 0.3 8.5 0.8 1.1 1 0 0 1 1 1 0 Prominin Gp-FAR-1 PF05823.7 EGO28526.1 - 0.86 9.5 6.0 0.85 9.5 1.9 2.0 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DDHD PF02862.12 EGO28526.1 - 0.98 9.1 7.9 1.1 8.9 5.5 1.1 1 0 0 1 1 1 0 DDHD domain FAM217 PF15344.1 EGO28526.1 - 1.6 8.2 6.8 2 7.9 4.7 1.1 1 0 0 1 1 1 0 FAM217 family Phasin PF05597.6 EGO28526.1 - 4.8 6.9 11.5 11 5.7 5.7 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RVP_2 PF08284.6 EGO28528.1 - 8.9e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO28528.1 - 0.0011 19.4 0.0 0.0015 19.0 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28528.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.1 EGO28529.1 - 0.022 14.4 2.4 0.039 13.6 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle CD24 PF14984.1 EGO28529.1 - 2.6 7.9 8.6 5.4 6.8 6.0 1.5 1 0 0 1 1 1 0 CD24 protein MT-A70 PF05063.9 EGO28530.1 - 3.5e-40 137.4 0.0 8.5e-40 136.1 0.0 1.6 1 1 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.10 EGO28530.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Noc2 PF03715.8 EGO28531.1 - 5.5e-99 330.8 1.1 6.6e-98 327.2 0.2 2.1 2 0 0 2 2 2 2 Noc2p family 5HT_transporter PF03491.8 EGO28534.1 - 0.031 14.3 0.7 0.085 12.9 0.5 1.8 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus HSP70 PF00012.15 EGO28535.1 - 5.2e-05 21.3 0.0 0.0001 20.4 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.15 EGO28535.1 - 0.085 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 EGO28535.1 - 0.15 10.5 0.1 0.61 8.6 0.1 1.8 2 0 0 2 2 2 0 MreB/Mbl protein ALO PF04030.9 EGO28536.1 - 2.9e-78 263.0 0.2 3.6e-78 262.7 0.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EGO28536.1 - 4.1e-26 91.1 0.2 6.7e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.21 EGO28537.1 - 1.4e-44 150.9 0.0 1.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNA_pol_Rpb2_6 PF00562.23 EGO28538.1 - 1.1e-115 386.5 0.8 1.4e-105 353.2 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGO28538.1 - 1.2e-55 187.6 0.0 6.8e-55 185.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EGO28538.1 - 7.4e-29 99.8 0.1 1.9e-28 98.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EGO28538.1 - 1.2e-27 96.5 0.0 3.4e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EGO28538.1 - 1.6e-22 79.0 1.5 5.2e-22 77.4 0.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGO28538.1 - 2.6e-21 75.1 0.0 6.7e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGO28538.1 - 5e-14 51.9 0.1 1.3e-13 50.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SNF2_N PF00176.18 EGO28540.1 - 3.9e-37 127.6 0.1 9.3e-37 126.4 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO28540.1 - 1.2e-15 57.0 0.0 2.9e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain VIGSSK PF14773.1 EGO28540.1 - 0.001 18.9 0.2 0.0043 16.9 0.0 2.1 1 1 1 2 2 2 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 EGO28540.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGO28540.1 - 0.041 12.6 0.0 0.23 10.2 0.0 2.0 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 UQ_con PF00179.21 EGO28541.1 - 2.4e-45 153.4 0.0 2.8e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO28541.1 - 0.0046 16.7 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B SHP PF03579.8 EGO28542.1 - 0.055 12.8 1.3 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 Small hydrophobic protein 7TM_GPCR_Srh PF10318.4 EGO28542.1 - 0.056 12.2 5.3 0.25 10.0 3.7 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Cytochrom_B561 PF03188.11 EGO28542.1 - 0.13 12.1 0.9 0.54 10.0 0.5 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2463 PF09591.5 EGO28542.1 - 0.14 11.7 4.6 3.7 7.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2463) zf-CCHC PF00098.18 EGO28543.1 - 1.1e-07 31.4 5.6 4.8e-07 29.3 2.0 2.6 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28543.1 - 0.00025 21.0 0.1 0.00073 19.5 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO28543.1 - 0.044 13.5 2.7 0.12 12.1 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 EGO28544.1 - 0.0028 17.6 0.0 0.0052 16.7 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO28544.1 - 0.0091 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28544.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EGO28545.1 - 7.6e-09 35.5 0.2 7.6e-09 35.5 0.2 3.0 3 1 1 4 4 4 1 Retrotransposon gag protein Got1 PF04178.7 EGO28546.1 - 0.097 12.7 2.3 0.13 12.3 1.6 1.2 1 0 0 1 1 1 0 Got1/Sft2-like family DUF3414 PF11894.3 EGO28547.1 - 3.6e-257 856.2 0.0 4.6e-257 855.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) STAS_2 PF13466.1 EGO28547.1 - 0.0012 18.8 0.1 0.0063 16.5 0.1 2.3 1 0 0 1 1 1 1 STAS domain Acetyltransf_1 PF00583.19 EGO28548.1 - 2.7e-15 56.1 0.0 4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO28548.1 - 4.9e-08 32.6 0.1 7.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO28548.1 - 1.2e-07 31.7 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO28548.1 - 1.2e-06 28.5 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO28548.1 - 1.9e-06 28.0 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO28548.1 - 2.8e-05 23.9 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO28548.1 - 4.8e-05 23.5 0.0 6.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO28548.1 - 0.002 18.0 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGO28548.1 - 0.02 14.4 0.2 0.036 13.6 0.1 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HSP70 PF00012.15 EGO28549.1 - 9.9e-265 879.1 5.9 1.1e-264 878.9 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO28549.1 - 4.7e-17 61.5 0.8 3e-16 58.9 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EGO28549.1 - 0.00035 19.4 0.6 0.031 13.1 0.1 2.4 2 1 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EGO28549.1 - 0.0067 15.5 3.5 0.051 12.6 0.1 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase NPV_P10 PF05531.7 EGO28549.1 - 0.12 12.6 1.4 0.51 10.6 0.3 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 EGO28549.1 - 1.7 8.9 8.3 2.9 8.2 0.4 3.3 2 2 1 3 3 3 0 Spectrin repeat AA_permease_2 PF13520.1 EGO28550.1 - 2.8e-62 210.6 59.8 3.5e-62 210.3 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO28550.1 - 1.2e-17 63.4 54.7 2.5e-17 62.4 38.0 1.3 1 1 0 1 1 1 1 Amino acid permease Peptidase_M28 PF04389.12 EGO28551.1 - 2e-26 92.8 0.0 4.1e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGO28551.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EGO28551.1 - 0.0042 16.3 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 Nicastrin zf-Tim10_DDP PF02953.10 EGO28552.1 - 4.6e-24 83.4 0.6 5.2e-24 83.3 0.4 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger 2-Hacid_dh_C PF02826.14 EGO28553.1 - 5.9e-40 136.2 0.0 1.2e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO28553.1 - 1.5e-33 115.0 0.0 2.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO28553.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGO28553.1 - 0.022 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2597 PF10772.4 EGO28553.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) SEF14_adhesin PF06443.6 EGO28555.1 - 0.16 11.5 1.3 0.38 10.3 0.9 1.6 1 1 0 1 1 1 0 SEF14-like adhesin Amidohydro_2 PF04909.9 EGO28556.1 - 1.6e-32 113.2 0.0 2.5e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EGO28556.1 - 0.00027 20.2 0.0 0.0051 16.0 0.0 2.1 2 0 0 2 2 2 2 TatD related DNase DUF89 PF01937.14 EGO28557.1 - 2.4e-96 322.6 0.0 3e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 BolA PF01722.13 EGO28557.1 - 3.8e-15 55.5 0.2 7.9e-15 54.5 0.2 1.5 1 0 0 1 1 1 1 BolA-like protein Amino_oxidase PF01593.19 EGO28558.1 - 4.8e-62 210.4 0.0 6e-48 164.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO28558.1 - 3.9e-10 39.6 0.8 8.2e-10 38.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO28558.1 - 2.2e-06 27.8 0.5 0.00088 19.3 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO28558.1 - 0.00063 18.9 0.7 0.001 18.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGO28558.1 - 0.00072 19.9 0.2 0.26 11.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO28558.1 - 0.0012 17.8 1.0 0.015 14.2 0.3 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO28558.1 - 0.0012 17.7 0.6 0.002 17.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGO28558.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EGO28558.1 - 0.0016 17.9 0.1 0.0034 16.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EGO28558.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO28558.1 - 0.021 13.6 0.1 0.047 12.5 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Herpes_U55 PF06501.6 EGO28558.1 - 0.023 13.2 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U55 protein Lycopene_cycl PF05834.7 EGO28558.1 - 0.032 13.1 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGO28558.1 - 0.17 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EGO28558.1 - 0.19 10.1 0.4 0.42 9.0 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein NfeD PF01957.13 EGO28559.1 - 0.14 12.2 7.2 0.47 10.5 2.7 2.9 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DDE_1 PF03184.14 EGO28561.1 - 2.2e-13 49.8 0.0 4.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO28561.1 - 0.0003 20.5 0.0 0.00087 19.0 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease 4HBT PF03061.17 EGO28562.1 - 4.7e-07 29.8 0.1 0.013 15.6 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF3339 PF11820.3 EGO28563.1 - 0.093 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3339) Pkinase PF00069.20 EGO28565.1 - 3.5e-52 177.1 0.0 5e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28565.1 - 8.2e-48 162.7 0.0 1.1e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EGO28565.1 - 4.1e-07 29.6 1.8 8.4e-07 28.6 1.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 EGO28565.1 - 0.0028 16.6 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO28565.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO28565.1 - 0.019 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 EGO28565.1 - 0.047 13.3 4.0 0.095 12.4 2.8 1.5 1 0 0 1 1 1 0 PHD-finger DUF566 PF04484.7 EGO28565.1 - 0.2 11.1 1.2 0.3 10.5 0.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Prok-RING_1 PF14446.1 EGO28565.1 - 1 9.1 5.3 2.6 7.8 3.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Transp_cyt_pur PF02133.10 EGO28566.1 - 4.3e-106 355.0 36.2 5.1e-106 354.8 25.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_holin_1 PF04531.8 EGO28567.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage holin Dabb PF07876.7 EGO28568.1 - 9.3e-16 58.0 0.1 1e-15 57.9 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Lon_2 PF13337.1 EGO28568.1 - 0.056 11.8 0.0 0.07 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Turandot PF07240.6 EGO28568.1 - 0.079 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot adh_short PF00106.20 EGO28570.1 - 5.6e-19 68.6 0.2 1e-18 67.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO28570.1 - 2.9e-14 53.4 0.2 5.5e-14 52.5 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO28570.1 - 3.2e-06 26.9 0.2 7.5e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO28570.1 - 0.0007 19.6 0.2 0.054 13.4 0.0 2.3 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO28570.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO28570.1 - 0.12 12.2 2.9 5.4 6.8 0.1 3.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PEMT PF04191.8 EGO28571.1 - 2.1e-31 108.1 4.4 5.2e-31 106.9 2.1 2.1 3 0 0 3 3 3 1 Phospholipid methyltransferase PsbM PF05151.7 EGO28571.1 - 0.04 13.5 0.1 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) F-box-like PF12937.2 EGO28572.1 - 7.5e-08 31.9 3.6 2e-07 30.6 2.5 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EGO28572.1 - 0.05 13.3 0.1 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Retrotrans_gag PF03732.12 EGO28573.1 - 2.5e-06 27.4 1.5 2.5e-06 27.4 1.1 2.6 2 2 1 3 3 3 1 Retrotransposon gag protein BORG_CEP PF14957.1 EGO28573.1 - 0.15 12.9 0.7 0.3 12.0 0.5 1.4 1 0 0 1 1 1 0 Cdc42 effector Cut8_N PF14482.1 EGO28574.1 - 0.059 13.3 0.4 0.059 13.3 0.3 2.2 2 0 0 2 2 2 0 Cut8 proteasome-binding domain UQ_con PF00179.21 EGO28577.1 - 3.4e-38 130.2 0.0 4.6e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC1 PF03109.11 EGO28579.1 - 2.9e-29 101.4 0.0 4.8e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 EGO28579.1 - 0.11 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) HflK_N PF12221.3 EGO28579.1 - 0.75 9.5 3.5 0.78 9.5 0.0 2.7 4 0 0 4 4 4 0 Bacterial membrane protein N terminal Peptidase_S28 PF05577.7 EGO28580.1 - 2.7e-44 151.4 0.8 5.5e-44 150.4 0.6 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGO28580.1 - 0.00018 20.8 0.0 0.00032 19.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 EGO28583.1 - 5.2e-50 170.2 0.1 9.3e-50 169.4 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGO28583.1 - 0.00045 19.4 0.1 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_3 PF00933.16 EGO28584.1 - 2.1e-81 273.1 0.1 2.9e-81 272.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO28584.1 - 1.1e-59 201.7 0.0 3.2e-59 200.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO28584.1 - 8.3e-20 70.5 0.0 2.1e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain SNARE PF05739.14 EGO28585.1 - 0.00016 21.2 3.2 0.00016 21.2 2.2 3.4 4 0 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 EGO28585.1 - 0.00048 20.1 6.9 0.12 12.4 0.3 2.8 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus NACHT PF05729.7 EGO28586.1 - 1.3e-09 37.9 0.0 3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain HNH_2 PF13391.1 EGO28586.1 - 3.9e-08 32.9 0.0 9.5e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Arch_ATPase PF01637.13 EGO28586.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EGO28586.1 - 0.00023 21.2 0.0 0.0012 18.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO28586.1 - 0.0023 18.0 0.0 0.0085 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO28586.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EGO28586.1 - 0.017 13.9 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EGO28586.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGO28586.1 - 0.11 12.6 0.0 0.82 9.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EGO28586.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.9 EGO28586.1 - 0.23 10.4 0.7 0.85 8.5 0.1 1.7 1 1 1 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.1 EGO28586.1 - 0.24 12.2 0.5 1.5 9.6 0.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGO28586.1 - 0.25 10.9 0.0 0.66 9.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 EGO28587.1 - 8.6e-30 102.1 0.1 5.9e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO28587.1 - 8.5e-23 80.1 0.0 1.3e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO28587.1 - 3.4e-12 46.0 0.0 5.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EGO28588.1 - 1e-80 271.1 0.0 1.5e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGO28588.1 - 5.2e-13 48.5 0.1 1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Condensation domain Methyltransf_31 PF13847.1 EGO28588.1 - 3.5e-12 46.1 0.0 1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGO28588.1 - 5.8e-11 42.5 0.0 2e-10 40.7 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EGO28588.1 - 1.4e-10 41.4 0.0 1.4e-09 38.2 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO28588.1 - 1.4e-10 41.6 0.0 8.8e-10 39.1 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO28588.1 - 9.9e-10 38.7 0.0 7.4e-09 35.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain AMP-binding_C PF13193.1 EGO28588.1 - 2.7e-09 37.8 0.6 0.00016 22.5 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_26 PF13659.1 EGO28588.1 - 6.4e-09 35.8 0.1 6.5e-08 32.6 0.0 2.8 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO28588.1 - 1.6e-08 34.4 0.0 4.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO28588.1 - 4e-08 33.5 0.0 1.3e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO28588.1 - 5.8e-07 29.0 0.0 2.1e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 EGO28588.1 - 7.3e-07 28.7 0.0 1.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.13 EGO28588.1 - 0.0015 17.8 0.1 0.014 14.6 0.0 2.6 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain MetW PF07021.7 EGO28588.1 - 0.019 14.3 0.0 0.055 12.8 0.0 1.7 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 EGO28588.1 - 0.023 14.1 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EGO28588.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EGO28588.1 - 0.088 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sugar_tr PF00083.19 EGO28589.1 - 2.8e-98 329.4 17.4 3.2e-98 329.2 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO28589.1 - 5.4e-30 104.2 25.0 6.3e-19 67.8 0.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGO28589.1 - 0.00088 17.4 1.4 0.0015 16.6 1.0 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SurE PF01975.12 EGO28589.1 - 0.11 11.8 1.0 0.18 11.0 0.7 1.3 1 0 0 1 1 1 0 Survival protein SurE DUF3040 PF11239.3 EGO28589.1 - 0.34 10.9 4.3 6.4 6.9 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) MR_MLE_C PF13378.1 EGO28590.1 - 2.2e-21 75.9 0.0 7.7e-21 74.1 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGO28590.1 - 2.1e-11 44.1 0.0 4.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGO28590.1 - 7.6e-11 42.0 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.24 EGO28592.1 - 2.7e-54 182.9 0.0 8.2e-44 148.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EGO28592.1 - 5.1e-22 77.7 1.1 1.6e-21 76.1 0.8 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EGO28592.1 - 1.6e-08 34.7 1.6 0.0051 16.8 0.1 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EGO28592.1 - 1.9e-06 28.6 0.0 0.007 17.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGO28592.1 - 5.3e-06 26.3 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO28592.1 - 0.00075 19.6 1.1 0.21 11.7 0.0 4.3 3 2 0 3 3 2 1 AAA domain AAA_2 PF07724.9 EGO28592.1 - 0.00075 19.4 0.0 0.061 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGO28592.1 - 0.00093 18.9 0.4 0.45 10.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO28592.1 - 0.0021 17.1 0.0 0.0057 15.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGO28592.1 - 0.0026 17.2 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO28592.1 - 0.0067 15.5 1.3 0.11 11.5 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EGO28592.1 - 0.0067 16.5 0.0 0.54 10.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EGO28592.1 - 0.0082 15.8 0.0 0.96 9.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EGO28592.1 - 0.0091 16.3 0.1 1.5 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain Vps4_C PF09336.5 EGO28592.1 - 0.013 15.4 1.0 0.098 12.5 0.0 2.9 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain NACHT PF05729.7 EGO28592.1 - 0.014 15.0 0.6 6.8 6.3 0.0 3.8 3 1 0 3 3 3 0 NACHT domain AAA_25 PF13481.1 EGO28592.1 - 0.023 14.0 2.8 2.1 7.6 0.1 3.9 3 2 2 5 5 5 0 AAA domain TIP49 PF06068.8 EGO28592.1 - 0.024 13.3 0.0 0.13 10.9 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 EGO28592.1 - 0.027 14.3 0.3 0.17 11.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 EGO28592.1 - 0.032 13.7 0.0 0.1 12.0 0.0 1.9 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EGO28592.1 - 0.1 12.2 0.0 0.96 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EGO28592.1 - 0.53 10.1 0.0 0.53 10.1 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase Phage_holin_4 PF05105.7 EGO28593.1 - 0.18 11.4 3.2 0.31 10.7 2.2 1.5 1 1 0 1 1 1 0 Holin family p450 PF00067.17 EGO28594.1 - 2.9e-53 181.0 0.0 3.5e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 EGO28595.1 - 4.9e-50 169.7 3.9 6e-50 169.4 1.9 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO28595.1 - 5.2e-33 114.0 3.3 5.2e-33 114.0 2.3 3.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO28595.1 - 2.6e-27 96.6 0.0 5e-26 92.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO28595.1 - 2.4e-17 62.6 0.0 4.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO28595.1 - 2.2e-14 54.1 0.0 7.5e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO28595.1 - 1.1e-07 31.7 0.3 1.8e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO28595.1 - 0.0018 17.7 0.1 0.0037 16.6 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PseudoU_synth_2 PF00849.17 EGO28596.1 - 1.3e-27 96.6 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Hydrolase_4 PF12146.3 EGO28596.1 - 0.087 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Y_Y_Y PF07495.8 EGO28597.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Y_Y_Y domain E1-E2_ATPase PF00122.15 EGO28598.1 - 2.8e-50 170.4 4.2 2.8e-50 170.4 2.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGO28598.1 - 8.3e-29 101.5 0.0 7.9e-28 98.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGO28598.1 - 6.3e-27 94.2 4.6 6.3e-27 94.2 3.2 2.8 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EGO28598.1 - 1.6e-18 66.4 0.0 2.8e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO28598.1 - 6.4e-16 59.0 0.0 2.6e-14 53.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO28598.1 - 8.7e-08 32.0 0.1 1.6e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P16-Arc PF04699.9 EGO28599.1 - 2.1e-49 167.4 0.0 2.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) BAR PF03114.13 EGO28601.1 - 1.3e-37 129.5 13.7 1.7e-37 129.1 9.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGO28601.1 - 2.5e-15 55.5 0.3 6.1e-15 54.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGO28601.1 - 4.3e-13 48.6 0.1 8.3e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO28601.1 - 1.2e-09 37.5 0.0 2.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain V_ATPase_I PF01496.14 EGO28601.1 - 7.2 4.3 8.0 9.2 3.9 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SWIB PF02201.13 EGO28602.1 - 5.8e-18 64.3 0.0 1.3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3638 PF12340.3 EGO28603.1 - 8.5e-82 273.5 0.5 1.5e-81 272.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EGO28603.1 - 3.4e-16 58.0 1.4 5e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) SpoIISA_toxin PF14171.1 EGO28604.1 - 1.1 8.4 8.4 1.6 7.9 5.9 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF1365 PF07103.6 EGO28606.1 - 1.3e-34 119.4 0.0 3.2e-34 118.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) SET PF00856.23 EGO28607.1 - 5.7e-19 68.9 0.3 5.7e-19 68.9 0.2 3.5 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EGO28607.1 - 1.1e-16 60.5 15.0 1.1e-16 60.5 10.4 2.3 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EGO28607.1 - 0.0048 16.3 0.1 0.0048 16.3 0.1 2.6 3 0 0 3 3 3 1 TFIIS helical bundle-like domain RNA_pol_I_A49 PF06870.7 EGO28608.1 - 1.8e-89 300.0 0.1 2.1e-89 299.8 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.20 EGO28609.1 - 2.5e-40 138.2 0.0 3.1e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28609.1 - 4.4e-30 104.6 0.0 6.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO28609.1 - 2.5e-06 26.6 0.0 3.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO28609.1 - 0.0056 16.4 0.1 0.68 9.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family BP28CT PF08146.7 EGO28610.1 - 8.8e-27 93.7 3.0 1.2e-26 93.2 0.8 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EGO28610.1 - 2.4e-08 33.9 0.2 2.4e-08 33.9 0.1 5.1 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 Polyketide_cyc2 PF10604.4 EGO28613.1 - 4.8e-08 33.2 0.2 6.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EGO28613.1 - 0.015 15.2 1.6 0.036 14.0 1.1 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 EGO28613.1 - 0.13 12.3 3.0 0.38 10.8 2.1 1.8 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein DUF2132 PF09905.4 EGO28614.1 - 0.36 10.8 1.1 0.86 9.6 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) RSN1_TM PF13967.1 EGO28617.1 - 0.0012 18.3 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF768 PF05589.6 EGO28618.1 - 0.051 13.5 0.1 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Nexin_C PF08628.7 EGO28618.1 - 0.053 13.6 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Sorting nexin C terminal PaO PF08417.7 EGO28618.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Pheophorbide a oxygenase DUF4381 PF14316.1 EGO28619.1 - 0.05 13.7 0.2 0.055 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF368 PF04018.8 EGO28621.1 - 0.024 13.8 0.9 0.032 13.4 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF368) DUF3816 PF12822.2 EGO28622.1 - 0.018 14.9 0.7 0.018 14.9 0.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Rhv PF00073.15 EGO28622.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 picornavirus capsid protein BAG PF02179.11 EGO28623.1 - 0.027 14.5 0.3 0.027 14.5 0.2 2.3 2 0 0 2 2 2 0 BAG domain DUF1675 PF07897.6 EGO28623.1 - 2.4 7.9 8.2 0.073 12.9 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) p450 PF00067.17 EGO28626.1 - 2.6e-53 181.1 0.0 1.7e-44 152.1 0.0 2.4 2 1 1 3 3 3 2 Cytochrome P450 p450 PF00067.17 EGO28627.1 - 8.9e-63 212.3 0.0 1.3e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.1 EGO28628.1 - 9.5e-22 76.9 0.0 4.4e-11 42.9 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO28628.1 - 9.8e-22 77.1 0.0 1.7e-13 50.7 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO28628.1 - 1.2e-21 76.2 0.0 3.4e-10 39.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGO28628.1 - 2.2e-20 71.3 0.0 7.2e-06 25.5 0.0 3.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGO28628.1 - 1.7e-14 52.4 0.0 0.00069 19.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat AAA_22 PF13401.1 EGO28629.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO28629.1 - 0.00026 21.0 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGO28629.1 - 0.00056 19.5 0.0 0.00095 18.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EGO28629.1 - 0.0049 15.8 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO28629.1 - 0.0066 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EGO28629.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EGO28629.1 - 0.03 14.0 0.0 0.15 11.7 0.0 1.9 1 1 1 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EGO28629.1 - 0.08 13.2 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGO28629.1 - 0.086 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EGO28629.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EGO28629.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus FAD_binding_1 PF00667.15 EGO28631.1 - 2.4e-37 128.5 0.0 3.6e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGO28631.1 - 2.7e-26 92.2 0.0 6e-26 91.1 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EGO28631.1 - 9e-12 45.5 0.0 1.9e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SNase PF00565.12 EGO28632.1 - 8.9e-19 67.7 0.0 1.7e-18 66.8 0.0 1.5 2 0 0 2 2 2 1 Staphylococcal nuclease homologue PH_4 PF15404.1 EGO28633.1 - 0.023 14.2 0.7 0.025 14.1 0.5 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain SNF2_N PF00176.18 EGO28634.1 - 4.1e-70 235.9 0.2 5.5e-70 235.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO28634.1 - 5.1e-14 51.8 0.0 1.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO28634.1 - 2.5e-05 24.1 0.3 7.5e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EGO28634.1 - 9.6e-05 21.9 2.5 9.6e-05 21.9 1.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO28634.1 - 9.9e-05 22.0 2.9 0.00021 21.0 2.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGO28634.1 - 0.00018 21.2 1.9 0.00048 19.9 1.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO28634.1 - 0.00018 21.1 0.8 0.00018 21.1 0.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGO28634.1 - 0.00038 20.4 1.8 0.00038 20.4 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO28634.1 - 0.0023 17.6 5.6 0.0066 16.1 3.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO28634.1 - 0.0061 16.2 3.8 0.017 14.8 2.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGO28634.1 - 0.14 11.8 3.6 11 5.6 0.1 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF4238 PF14022.1 EGO28635.1 - 4.6e-19 68.7 0.0 1.6e-18 66.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4238) DUF3638 PF12340.3 EGO28636.1 - 2.1e-85 285.3 0.2 3.8e-85 284.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EGO28636.1 - 1.5e-16 59.1 0.1 3e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Complex1_LYR PF05347.10 EGO28637.1 - 2.2e-10 40.1 0.3 4.1e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO28637.1 - 3.6e-07 30.2 0.1 6.4e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DUF1422 PF07226.6 EGO28640.1 - 0.082 12.6 1.9 0.12 12.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) PPR_2 PF13041.1 EGO28641.1 - 1.8e-14 53.4 0.0 5.9e-05 22.9 0.0 4.9 4 2 0 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EGO28641.1 - 5.5e-07 29.3 6.2 0.24 11.7 0.0 7.0 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EGO28641.1 - 0.00042 20.1 0.0 0.028 14.4 0.0 3.8 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 EGO28641.1 - 0.025 14.0 1.0 0.55 9.7 0.0 3.5 4 0 0 4 4 4 0 PPR repeat RRM_1 PF00076.17 EGO28642.1 - 1.4e-14 53.4 0.0 1.9e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO28642.1 - 2.5e-10 40.1 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO28642.1 - 8.8e-07 28.6 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO28642.1 - 0.00037 20.2 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 EGO28642.1 - 0.16 11.7 48.4 0.23 11.1 33.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Lyase_1 PF00206.15 EGO28644.1 - 2.6e-21 76.1 0.0 3.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGO28644.1 - 4.2e-16 58.7 0.0 9e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 EGO28644.1 - 0.051 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Pkinase PF00069.20 EGO28646.1 - 5e-64 215.9 0.0 7e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28646.1 - 1.4e-37 129.1 0.0 2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO28646.1 - 1.6e-06 27.3 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGO28646.1 - 0.00047 19.5 0.1 0.00077 18.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGO28646.1 - 0.011 15.5 0.6 0.051 13.2 0.2 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.6 EGO28646.1 - 0.037 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.4 EGO28646.1 - 0.049 12.9 0.4 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-H2C2 PF09337.5 EGO28648.1 - 0.0095 15.3 0.9 0.017 14.5 0.6 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger SKN1 PF03935.10 EGO28649.1 - 2.4e-184 613.1 0.6 2.7e-184 613.0 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EGO28649.1 - 0.00011 21.5 0.0 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 HEM4 PF02602.10 EGO28650.1 - 2.9e-32 111.7 0.0 3.3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PTPS PF01242.14 EGO28650.1 - 0.14 11.7 0.0 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase YscO PF07321.7 EGO28651.1 - 0.056 13.2 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Mito_carr PF00153.22 EGO28652.1 - 4.1e-69 228.3 4.3 5.3e-22 77.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EGO28652.1 - 0.0028 17.7 2.6 4.5 7.3 0.0 4.1 3 1 1 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family Zea_mays_MuDR PF05928.6 EGO28655.1 - 0.037 13.4 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF4381 PF14316.1 EGO28658.1 - 0.056 13.5 0.3 0.063 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Urb2 PF10441.4 EGO28659.1 - 0.1 12.1 0.1 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Urb2/Npa2 family LIN37 PF15306.1 EGO28659.1 - 0.43 10.5 2.8 0.19 11.6 0.3 1.6 2 0 0 2 2 2 0 LIN37 Nop14 PF04147.7 EGO28659.1 - 0.61 7.9 15.2 0.83 7.5 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EGO28659.1 - 3.9 6.4 15.4 5.6 5.9 10.7 1.2 1 0 0 1 1 1 0 BUD22 DUF4219 PF13961.1 EGO28660.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DUF496 PF04363.7 EGO28662.1 - 0.036 13.8 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Nbl1_Borealin_N PF10444.4 EGO28662.1 - 0.13 11.6 0.5 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal NACHT PF05729.7 EGO28663.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGO28663.1 - 0.00014 21.9 0.0 0.00021 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO28663.1 - 0.00023 20.2 0.0 0.00041 19.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO28663.1 - 0.0011 17.9 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EGO28663.1 - 0.0013 18.6 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO28663.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.9 EGO28663.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EGO28663.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EGO28663.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGO28663.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain WxL PF13731.1 EGO28663.1 - 0.078 12.7 0.4 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 WxL domain surface cell wall-binding AAA PF00004.24 EGO28663.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EGO28663.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DDE_1 PF03184.14 EGO28665.1 - 2.3e-25 88.9 0.0 3.1e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO28665.1 - 2.6e-05 23.9 0.0 0.00011 21.9 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease Macoilin PF09726.4 EGO28666.1 - 0.021 13.1 5.6 0.023 13.0 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 EGO28666.1 - 0.19 11.4 0.8 0.19 11.4 0.6 1.1 1 0 0 1 1 1 0 DDHD domain UBN2_2 PF14227.1 EGO28667.1 - 0.05 13.1 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EGO28668.1 - 1.2e-08 34.4 2.8 2.3e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28668.1 - 8.4e-08 32.1 0.7 2.4e-07 30.7 0.1 2.1 3 0 0 3 3 3 1 Retrotransposon gag protein Ras PF00071.17 EGO28670.1 - 5.8e-50 168.8 0.0 6.9e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO28670.1 - 1.4e-17 64.2 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO28670.1 - 4.1e-06 26.1 0.0 6.6e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO28670.1 - 0.024 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGO28670.1 - 0.17 11.4 0.0 3.2 7.2 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Pro_CA PF00484.14 EGO28671.1 - 6.9e-39 133.3 0.0 8.5e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 EGO28672.1 - 1.6e-30 106.1 0.0 3.4e-30 105.0 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Ribosomal_S24e PF01282.14 EGO28673.1 - 0.11 12.2 0.1 1 9.1 0.0 1.9 1 1 1 2 2 2 0 Ribosomal protein S24e DUF2254 PF10011.4 EGO28674.1 - 0.034 12.6 5.3 0.47 8.8 0.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF3611 PF12263.3 EGO28674.1 - 0.074 12.4 0.2 0.074 12.4 0.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3611) RINGv PF12906.2 EGO28675.1 - 2.1e-07 30.8 7.1 3.7e-07 30.0 4.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EGO28675.1 - 0.00019 21.2 6.4 0.00032 20.4 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO28675.1 - 0.0023 18.0 3.4 0.0043 17.1 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger PhnA_Zn_Ribbon PF08274.7 EGO28675.1 - 0.018 14.8 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-C3HC4_2 PF13923.1 EGO28675.1 - 0.028 14.4 3.6 0.061 13.3 2.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGO28675.1 - 0.04 13.8 3.3 0.078 12.9 2.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EGO28675.1 - 0.35 10.5 3.7 0.59 9.8 2.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 EGO28675.1 - 2.1 6.9 5.4 3.3 6.3 3.7 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor GTP_EFTU PF00009.22 EGO28676.1 - 9.6e-37 126.2 0.0 1.6e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGO28676.1 - 6.9e-36 122.1 0.5 1.5e-35 121.0 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGO28676.1 - 2.4e-11 43.5 0.5 2.4e-11 43.5 0.3 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO28676.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-primase PF09329.6 EGO28679.1 - 2.2e-13 49.5 1.9 4e-13 48.7 1.3 1.4 1 0 0 1 1 1 1 Primase zinc finger RasGEF PF00617.14 EGO28680.1 - 6.9e-23 81.3 0.3 2e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGO28680.1 - 2.4e-10 40.4 1.4 7e-10 38.9 0.9 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif UCH PF00443.24 EGO28681.1 - 5e-42 143.8 0.0 6.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO28681.1 - 5.2e-16 58.9 0.0 1.2e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGO28681.1 - 3.8e-06 26.2 0.0 9e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Bap31 PF05529.7 EGO28682.1 - 6e-54 182.4 5.1 6.9e-54 182.2 3.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Cortexin PF11057.3 EGO28682.1 - 0.0082 15.7 0.2 0.61 9.7 0.0 2.4 2 0 0 2 2 2 1 Cortexin of kidney DUF4446 PF14584.1 EGO28682.1 - 0.039 13.7 0.8 0.055 13.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF1361 PF07099.6 EGO28682.1 - 0.059 13.1 0.7 0.14 12.0 0.0 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1361) DUF95 PF01944.12 EGO28682.1 - 0.16 11.5 1.6 0.16 11.5 0.3 1.5 2 0 0 2 2 2 0 Integral membrane protein DUF95 DUF4094 PF13334.1 EGO28682.1 - 0.83 10.0 5.6 9.2 6.7 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF2681 PF10883.3 EGO28682.1 - 1.4 9.1 5.9 0.59 10.3 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) DUF2140 PF09911.4 EGO28682.1 - 1.8 7.7 4.7 0.28 10.3 0.2 1.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) COBRA1 PF06209.8 EGO28683.1 - 0.087 11.4 0.1 0.087 11.4 0.1 1.1 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) SET PF00856.23 EGO28684.1 - 8.5e-11 42.4 0.0 1.8e-09 38.1 0.0 2.5 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.1 EGO28684.1 - 3.4e-05 23.7 0.0 0.00015 21.6 0.0 2.1 2 0 0 2 2 2 1 HTH-like domain p450 PF00067.17 EGO28685.1 - 1.7e-72 244.4 0.0 4.2e-72 243.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DNA_pol_A_exo1 PF01612.15 EGO28686.1 - 4.4e-19 68.6 0.0 5.9e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.15 EGO28687.1 - 1.7e-16 60.2 0.0 2.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Glyco_hydro_18 PF00704.23 EGO28688.1 - 3.4e-19 69.4 1.6 5.2e-19 68.8 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.17 EGO28690.1 - 5.2e-66 223.0 0.0 1.5e-65 221.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 HLH PF00010.21 EGO28691.1 - 2.2e-13 49.6 1.3 3.6e-13 48.9 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain G-alpha PF00503.15 EGO28693.1 - 2e-122 408.6 0.0 2.2e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO28693.1 - 1.4e-10 40.7 0.2 1.9e-07 30.4 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 EGO28693.1 - 0.051 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGO28693.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EGO28693.1 - 0.12 11.5 0.1 4.8 6.2 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Na_H_Exchanger PF00999.16 EGO28694.1 - 1.8e-68 230.8 33.3 2.3e-68 230.4 23.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 60KD_IMP PF02096.15 EGO28695.1 - 2.7e-25 89.1 6.0 3.9e-25 88.6 4.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF202 PF02656.10 EGO28696.1 - 0.11 12.7 0.3 0.13 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) EF1_GNE PF00736.14 EGO28700.1 - 1.2e-29 101.7 1.1 2.4e-29 100.8 0.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EGO28700.1 - 1e-10 41.5 7.8 1e-10 41.5 5.4 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EGO28700.1 - 0.00052 20.4 0.0 0.0013 19.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO28700.1 - 0.027 14.4 0.2 0.17 11.8 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Pectate_lyase22 PF14583.1 EGO28705.1 - 0.12 10.7 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate lyase WD40 PF00400.27 EGO28708.1 - 9.9e-14 50.6 18.1 2.7e-07 30.2 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO28708.1 - 0.00039 20.1 0.0 1.9 8.1 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EGO28708.1 - 0.033 12.4 0.0 0.052 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) MFS_1 PF07690.11 EGO28710.1 - 1.9e-18 66.3 18.2 1.7e-16 59.9 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PHD PF00628.24 EGO28711.1 - 8.6e-08 31.7 9.6 1.5e-07 31.0 6.7 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EGO28711.1 - 0.018 15.3 0.0 0.073 13.3 0.0 1.8 2 0 0 2 2 2 0 SET domain PHD_2 PF13831.1 EGO28711.1 - 0.061 12.6 7.8 0.12 11.6 5.4 1.5 1 0 0 1 1 1 0 PHD-finger Sod_Fe_C PF02777.13 EGO28712.1 - 1.6e-36 124.3 0.2 2.4e-36 123.7 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGO28712.1 - 2.6e-31 107.7 3.2 2.6e-31 107.7 2.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain NACHT PF05729.7 EGO28713.1 - 9.2e-10 38.4 0.1 2.6e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EGO28713.1 - 0.00044 20.3 0.0 0.0016 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO28713.1 - 0.0044 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGO28713.1 - 0.0081 16.1 0.0 0.089 12.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.12 EGO28713.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.24 EGO28713.1 - 0.021 15.0 0.0 0.22 11.7 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EGO28713.1 - 0.069 11.9 0.0 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain HTH_17 PF12728.2 EGO28713.1 - 0.078 13.2 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_30 PF13604.1 EGO28713.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGO28713.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EGO28713.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Prok-JAB PF14464.1 EGO28714.1 - 0.048 13.2 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Terpene_synth_C PF03936.11 EGO28715.1 - 3.8e-21 75.5 0.0 5.1e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EGO28715.1 - 9.9e-05 21.1 0.1 0.00015 20.5 0.0 1.3 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 EGO28716.1 - 1.1e-62 212.0 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bac_rhamnosid PF05592.6 EGO28717.1 - 7.7e-32 110.1 1.0 1.1e-30 106.3 0.8 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EGO28717.1 - 0.01 14.4 0.8 0.018 13.7 0.5 1.3 1 0 0 1 1 1 0 Trehalase F-box-like PF12937.2 EGO28718.1 - 7.1e-06 25.6 0.0 2.7e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 F-box-like DUF3638 PF12340.3 EGO28719.1 - 7.4e-85 283.5 0.2 1.4e-84 282.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EGO28719.1 - 3.5e-16 58.0 0.1 7.9e-16 56.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SerH PF06873.6 EGO28719.1 - 0.35 9.4 0.9 0.71 8.4 0.6 1.4 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH PigN PF04987.9 EGO28720.1 - 9.4e-108 360.6 35.8 1.2e-107 360.3 24.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGO28720.1 - 8.9e-13 48.2 0.1 1.6e-08 34.2 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGO28720.1 - 0.00011 21.5 0.1 0.0005 19.3 0.1 1.8 2 0 0 2 2 2 1 Sulfatase Peroxidase_2 PF01328.12 EGO28721.1 - 1.4e-23 83.0 0.0 2.7e-23 82.1 0.0 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 Mito_carr PF00153.22 EGO28722.1 - 3.9e-63 209.1 1.7 1.1e-22 79.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.7 EGO28723.1 - 2.7e-18 65.4 0.6 3.5e-18 65.0 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.12 EGO28723.1 - 0.09 12.4 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Ribosomal_60s PF00428.14 EGO28723.1 - 0.35 11.3 2.5 0.54 10.6 1.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein COX14 PF14880.1 EGO28724.1 - 0.29 10.7 2.5 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly EAP30 PF04157.11 EGO28726.1 - 8.7e-34 116.6 0.0 8.3e-33 113.4 0.0 2.1 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EGO28726.1 - 7.2e-20 70.6 0.0 1.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EGO28726.1 - 0.021 13.9 13.1 0.19 10.8 2.2 2.8 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.2 EGO28726.1 - 0.051 13.3 4.5 0.34 10.7 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGO28726.1 - 1.2 8.3 6.4 3.3 7.0 1.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain STE PF02200.11 EGO28730.1 - 3.7e-41 139.7 0.2 5e-41 139.2 0.2 1.2 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EGO28731.1 - 5.3e-12 45.3 14.5 1.7e-06 28.0 2.0 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO28731.1 - 1.3e-09 37.7 13.0 4.1e-06 26.7 1.3 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO28731.1 - 1.3e-08 34.6 13.9 9.5e-08 31.9 5.6 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGO28731.1 - 0.00035 20.6 9.2 0.078 13.1 1.7 2.4 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO28731.1 - 0.00044 20.3 8.7 0.019 15.1 2.5 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 EGO28731.1 - 0.03 14.0 7.2 0.18 11.5 0.4 2.2 2 0 0 2 2 2 0 BED zinc finger C1_4 PF07975.7 EGO28731.1 - 0.069 13.1 0.8 0.091 12.7 0.6 1.3 1 0 0 1 1 1 0 TFIIH C1-like domain zf-CCHC_2 PF13696.1 EGO28731.1 - 0.1 12.0 1.6 0.21 11.1 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_2 PF12756.2 EGO28731.1 - 0.13 12.4 6.4 1.2 9.3 1.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ROS_MUCR PF05443.6 EGO28731.1 - 0.14 11.8 0.3 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Fer4_8 PF13183.1 EGO28731.1 - 0.15 12.1 0.6 0.18 11.8 0.4 1.1 1 0 0 1 1 1 0 4Fe-4S dicluster domain Transpos_assoc PF13963.1 EGO28731.1 - 0.26 11.3 2.9 0.4 10.6 2.0 1.4 1 1 0 1 1 1 0 Transposase-associated domain GAGA PF09237.6 EGO28731.1 - 0.74 9.4 3.7 2.2 7.9 1.3 1.9 1 1 1 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.1 EGO28731.1 - 2.8 7.9 9.8 0.2 11.6 1.1 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGO28731.1 - 3 8.2 16.4 1.5 9.2 3.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 EGO28731.1 - 4.3 7.1 6.4 13 5.6 0.4 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type EIIC-GAT PF03611.9 EGO28732.1 - 0.01 14.6 4.8 0.012 14.3 3.3 1.0 1 0 0 1 1 1 0 PTS system sugar-specific permease component DUF1687 PF07955.6 EGO28733.1 - 6.2e-12 45.6 0.0 7.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Phosphorylase PF00343.15 EGO28736.1 - 3.5e-290 964.0 0.0 4.2e-290 963.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase RRM_1 PF00076.17 EGO28739.1 - 5.1e-71 234.2 0.1 1.5e-17 62.9 0.0 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO28739.1 - 1.7e-63 210.4 0.1 1.3e-14 53.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO28739.1 - 1.9e-31 107.6 0.0 2.4e-08 33.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO28739.1 - 0.00017 21.2 0.0 10 5.9 0.0 5.0 6 0 0 6 6 6 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGO28739.1 - 0.00037 20.2 0.2 0.92 9.3 0.0 4.7 4 1 0 4 4 4 1 RNA binding motif Limkain-b1 PF11608.3 EGO28739.1 - 0.0012 18.5 0.0 2.5 7.9 0.0 4.1 4 1 0 4 4 4 1 Limkain b1 Integrase_AP2 PF14657.1 EGO28739.1 - 0.0022 17.7 2.2 2.6 7.8 0.2 3.9 3 0 0 3 3 3 1 AP2-like DNA-binding integrase domain DUF3343 PF11823.3 EGO28739.1 - 0.061 12.5 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RNA_pol_Rpb2_7 PF04560.15 EGO28739.1 - 0.21 11.8 0.6 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 Prefoldin PF02996.12 EGO28740.1 - 1.2e-26 92.7 2.6 6.7e-25 87.0 1.0 2.6 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGO28740.1 - 0.019 14.7 1.5 0.32 10.7 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit Exonuc_VII_S PF02609.11 EGO28740.1 - 0.076 12.7 0.3 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit Syntaxin-6_N PF09177.6 EGO28740.1 - 0.22 11.9 4.8 2.6 8.5 0.2 2.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CENP-Q PF13094.1 EGO28740.1 - 5 7.1 7.4 1.6 8.7 0.2 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Sugar_tr PF00083.19 EGO28741.1 - 1.1e-17 63.8 24.3 2.6e-17 62.5 16.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO28741.1 - 3.6e-14 52.2 48.2 3.5e-10 39.1 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 EGO28741.1 - 0.038 13.3 0.2 0.038 13.3 0.1 4.0 4 2 0 4 4 4 0 Domain of unknown function (DUF4131) MitoNEET_N PF10660.4 EGO28745.1 - 0.18 11.6 4.5 6.4 6.7 0.1 2.7 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus SNF2_N PF00176.18 EGO28746.1 - 1.4e-45 155.4 0.0 3.4e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EGO28746.1 - 1.2e-07 31.3 11.4 2.9e-07 30.2 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO28746.1 - 1.7e-06 27.5 8.9 2.9e-06 26.8 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO28746.1 - 3.7e-06 26.5 9.5 7.6e-06 25.4 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO28746.1 - 4.9e-06 26.1 10.8 8.5e-06 25.4 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO28746.1 - 2.2e-05 24.4 11.8 4.2e-05 23.4 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO28746.1 - 0.00052 20.0 7.9 0.0018 18.3 5.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EGO28746.1 - 0.061 12.8 4.9 0.15 11.6 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGO28746.1 - 0.11 12.3 5.3 0.44 10.4 3.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGO28746.1 - 2.9 7.8 10.1 5.9 6.8 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4200 PF13863.1 EGO28746.1 - 3.4 7.6 15.6 0.035 14.0 4.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Myb_DNA-binding PF00249.26 EGO28747.1 - 2.2e-17 62.8 0.4 1.8e-09 37.4 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO28747.1 - 5.3e-12 45.6 0.1 2.4e-05 24.3 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain PCI PF01399.22 EGO28748.1 - 2.4e-10 40.6 0.2 1.3e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 PCI domain F-box-like PF12937.2 EGO28749.1 - 4e-05 23.2 0.4 0.00015 21.4 0.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EGO28749.1 - 1.2 8.9 6.0 5.1 6.9 0.6 3.4 3 0 0 3 3 3 0 Leucine rich repeat PEMT PF04191.8 EGO28750.1 - 2.8e-13 49.8 0.5 1.4e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EGO28750.1 - 8.2e-13 48.3 0.3 2.1e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EGO28750.1 - 8.4e-05 21.2 0.2 0.00011 20.9 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGO28750.1 - 0.12 11.6 0.6 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) ICMT PF04140.9 EGO28751.1 - 4.6e-13 49.1 1.2 8.1e-13 48.3 0.0 2.1 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGO28751.1 - 6.3e-12 45.5 2.7 7.5e-12 45.2 0.2 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EGO28751.1 - 2.1e-06 26.5 0.4 2.9e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGO28751.1 - 0.046 13.0 0.3 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) AP_endonuc_2 PF01261.19 EGO28752.1 - 7.4e-28 97.2 0.0 1.6e-27 96.2 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel STE3 PF02076.10 EGO28753.1 - 1.2e-104 349.4 16.0 1.4e-104 349.1 11.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor HAD_2 PF13419.1 EGO28754.1 - 3.2e-23 82.8 0.0 4.4e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO28754.1 - 2.6e-07 31.2 0.0 5.3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO28754.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like STE3 PF02076.10 EGO28756.1 - 1.3e-74 250.8 18.2 1.5e-74 250.6 12.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF3584 PF12128.3 EGO28757.1 - 0.0038 14.6 5.3 0.0051 14.2 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) RelB_N PF12910.2 EGO28757.1 - 0.016 14.5 0.6 0.055 12.8 0.1 2.1 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal Hydantoinase_B PF02538.9 EGO28757.1 - 0.054 11.7 0.1 0.076 11.2 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase VSG_B PF13206.1 EGO28757.1 - 0.088 11.9 0.8 0.14 11.3 0.6 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain CorA PF01544.13 EGO28757.1 - 0.15 11.0 0.2 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PilJ PF13675.1 EGO28757.1 - 0.26 11.6 2.8 1.1 9.5 0.3 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.5 EGO28757.1 - 0.56 10.3 3.1 0.9 9.6 2.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family STE3 PF02076.10 EGO28759.1 - 1.3e-90 303.2 19.4 1.5e-90 303.1 13.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EGO28760.1 - 7.3e-105 350.0 27.1 8.5e-105 349.8 18.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EGO28761.1 - 2.5e-103 345.0 16.4 3e-103 344.8 11.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Fascin PF06268.8 EGO28762.1 - 0.0025 17.8 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Fascin domain Agglutinin PF07468.6 EGO28762.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Agglutinin Fascin PF06268.8 EGO28763.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Fascin domain DUF2767 PF10965.3 EGO28764.1 - 0.13 12.1 0.2 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) CobA_CobO_BtuR PF02572.10 EGO28765.1 - 0.059 12.9 0.2 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP HSCB_C PF07743.8 EGO28765.1 - 1.2 9.5 6.4 0.18 12.2 0.7 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF3959 PF13105.1 EGO28767.1 - 0.16 11.2 0.8 0.15 11.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DctQ PF04290.7 EGO28768.1 - 0.0081 15.9 0.1 1.4 8.7 0.1 2.1 2 0 0 2 2 2 2 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2363 PF10155.4 EGO28769.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) Pkinase PF00069.20 EGO28770.1 - 7.5e-74 248.1 1.2 1.1e-73 247.5 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28770.1 - 8.8e-53 179.0 0.6 3.6e-52 176.9 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGO28770.1 - 1.2e-21 76.8 0.0 3.4e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EGO28770.1 - 1.2e-07 30.9 0.0 1.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EGO28770.1 - 5.5e-06 26.5 0.9 1.3e-05 25.3 0.3 1.9 2 0 0 2 2 2 1 PH domain APH PF01636.18 EGO28770.1 - 0.0016 18.2 0.1 0.0047 16.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S19 PF00203.16 EGO28771.1 - 2.5e-22 78.2 0.0 3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Glutaminase PF04960.10 EGO28772.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Glutaminase HCV_NS4b PF01001.14 EGO28772.1 - 0.14 11.5 4.4 0.69 9.2 0.0 2.1 1 1 1 2 2 2 0 Hepatitis C virus non-structural protein NS4b Glyco_transf_20 PF00982.16 EGO28773.1 - 7.5e-141 469.8 0.0 9.9e-141 469.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGO28773.1 - 9.8e-21 73.7 0.0 1.7e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF1087 PF06465.8 EGO28773.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) F-box-like PF12937.2 EGO28774.1 - 0.00026 20.6 0.4 0.00092 18.8 0.3 2.0 1 0 0 1 1 1 1 F-box-like Misat_Tub_SegII PF10644.4 EGO28775.1 - 4.3e-35 120.2 0.1 9.4e-35 119.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGO28775.1 - 7.4e-33 113.5 0.0 1.2e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EGO28775.1 - 6.5e-07 29.3 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Sec66 PF09802.4 EGO28775.1 - 0.028 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 KAP_NTPase PF07693.9 EGO28777.1 - 0.034 13.1 0.7 0.19 10.6 0.4 1.9 1 1 1 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 EGO28777.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RPA_C PF08784.6 EGO28777.1 - 0.13 12.7 1.1 0.41 11.0 0.4 1.8 2 0 0 2 2 2 0 Replication protein A C terminal BTB PF00651.26 EGO28779.1 - 5.1e-09 36.1 0.0 1.2e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain RNB PF00773.14 EGO28780.1 - 0.03 13.6 0.0 0.061 12.6 0.0 1.5 2 0 0 2 2 2 0 RNB domain PDCD2_C PF04194.8 EGO28781.1 - 5.7e-29 100.8 0.8 2.3e-28 98.8 0.0 2.3 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain MCPVI PF02993.9 EGO28781.1 - 2.6 8.1 7.2 0.24 11.5 1.8 1.6 2 0 0 2 2 2 0 Minor capsid protein VI ApoO PF09769.4 EGO28782.1 - 9.2e-30 103.4 0.0 1.7e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O Lentivirus_VIF PF05851.6 EGO28785.1 - 0.039 12.6 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) PgaD PF13994.1 EGO28785.1 - 0.2 11.1 2.1 0.26 10.7 1.4 1.1 1 0 0 1 1 1 0 PgaD-like protein SNF2_N PF00176.18 EGO28787.1 - 1.5e-59 201.2 0.0 2.8e-59 200.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO28787.1 - 4.6e-15 55.2 0.0 2.2e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.24 EGO28787.1 - 1.5e-05 24.5 19.3 4e-05 23.2 5.8 3.3 2 1 1 3 3 3 2 PHD-finger HDA2-3 PF11496.3 EGO28787.1 - 1.7e-05 23.7 3.1 0.0075 15.1 0.0 3.2 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 NOA36 PF06524.7 EGO28787.1 - 0.38 9.9 9.4 0.69 9.1 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein zf-PHD-like PF15446.1 EGO28787.1 - 1.4 8.2 14.7 0.26 10.5 1.0 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EGO28787.1 - 1.8 8.3 22.0 0.12 12.1 2.5 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EGO28787.1 - 5.7 6.8 18.4 14 5.6 7.1 2.8 1 1 1 2 2 2 0 Ring finger domain DPM3 PF08285.6 EGO28788.1 - 2e-33 114.0 0.1 2.2e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) OapA_N PF08525.6 EGO28788.1 - 0.13 12.0 0.7 0.23 11.2 0.5 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif EmrE PF13536.1 EGO28789.1 - 4.1e-08 33.4 6.7 4.1e-08 33.4 4.6 3.4 2 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EGO28789.1 - 0.0027 16.8 0.3 0.0063 15.6 0.2 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter Antimicrobial10 PF08105.6 EGO28789.1 - 0.0041 16.7 0.8 0.4 10.3 0.0 3.0 3 0 0 3 3 3 1 Metchnikowin family adh_short PF00106.20 EGO28792.1 - 5e-24 85.1 0.1 6.5e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO28792.1 - 3.4e-13 49.9 0.0 4.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO28792.1 - 5.5e-07 29.4 0.1 9.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO28792.1 - 8.4e-07 29.1 0.1 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO28792.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGO28792.1 - 0.0096 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Syndecan PF01034.15 EGO28793.1 - 3.6 7.3 4.8 7.6 6.2 0.2 2.7 2 0 0 2 2 2 0 Syndecan domain DUF1620 PF07774.8 EGO28795.1 - 1.7e-66 223.5 0.1 2.8e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EGO28795.1 - 3.1e-15 56.3 1.2 7.5e-09 35.4 0.0 3.8 2 1 0 3 3 3 3 PQQ-like domain PQQ PF01011.16 EGO28795.1 - 3.4e-09 35.7 0.1 0.0041 16.5 0.0 3.7 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 EGO28795.1 - 3 8.2 6.9 3.4 8.0 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain Metallophos PF00149.23 EGO28796.1 - 1.6e-40 138.6 0.1 2e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 EGO28797.1 - 1.1e-18 67.7 0.6 2e-18 66.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO28797.1 - 3.8e-07 29.9 0.6 9.3e-07 28.6 0.4 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO28797.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding DUF3435 PF11917.3 EGO28798.1 - 0.00057 18.7 0.2 0.00065 18.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_B PF02304.10 EGO28798.1 - 0.11 12.7 0.2 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Scaffold protein B zf-CCHC PF00098.18 EGO28799.1 - 1.1e-07 31.3 2.4 1.9e-07 30.6 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO28799.1 - 0.025 14.3 2.9 0.042 13.5 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Phage_terminase PF10668.4 EGO28800.1 - 0.17 11.6 2.1 0.41 10.4 1.4 1.5 1 0 0 1 1 1 0 Phage terminase small subunit zf-CCHC PF00098.18 EGO28801.1 - 2.8e-08 33.2 1.1 4e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO28801.1 - 0.076 12.6 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO28801.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle TLD PF07534.11 EGO28804.1 - 5.5e-06 26.4 0.0 5.9e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 TLD PAD_M PF08527.5 EGO28805.1 - 1.4 8.2 4.5 2.6 7.4 3.1 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain adh_short PF00106.20 EGO28806.1 - 1.3e-20 73.9 0.0 2.8e-20 72.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO28806.1 - 1.9e-12 47.2 0.0 2.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO28806.1 - 1e-08 35.2 0.0 9.6e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGO28806.1 - 3.3e-05 23.4 0.0 5.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO28806.1 - 0.00032 19.4 0.2 0.00073 18.3 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO28806.1 - 0.002 18.1 0.6 0.012 15.6 0.1 2.3 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGO28806.1 - 0.048 12.5 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EGO28806.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Flavi_propep PF01570.12 EGO28806.1 - 0.14 11.8 0.1 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Flavivirus polyprotein propeptide RmlD_sub_bind PF04321.12 EGO28806.1 - 0.16 10.8 0.1 0.29 9.9 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain AAA_5 PF07728.9 EGO28807.1 - 0.00011 21.9 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Septin PF00735.13 EGO28807.1 - 0.00028 20.0 0.1 0.1 11.5 0.0 2.3 1 1 0 2 2 2 2 Septin G-alpha PF00503.15 EGO28807.1 - 0.00047 18.9 0.1 0.014 14.0 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit Miro PF08477.8 EGO28807.1 - 0.00055 20.4 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EGO28807.1 - 0.00062 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO28807.1 - 0.0014 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO28807.1 - 0.0024 18.6 0.3 0.011 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO28807.1 - 0.0033 17.4 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 EGO28807.1 - 0.006 16.0 0.0 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EGO28807.1 - 0.012 14.5 0.0 0.033 13.1 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 EGO28807.1 - 0.023 14.2 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EGO28807.1 - 0.028 13.5 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EGO28807.1 - 0.028 14.1 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EGO28807.1 - 0.035 14.3 0.0 0.086 13.1 0.0 1.8 2 0 0 2 2 1 0 ABC transporter DUF815 PF05673.8 EGO28807.1 - 0.044 12.7 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SMC_N PF02463.14 EGO28807.1 - 0.063 12.4 0.0 0.17 11.0 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGO28807.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EGO28809.1 - 1.6e-06 28.5 0.1 5e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO28809.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EGO28809.1 - 2.5e-05 23.4 0.1 0.0078 15.2 0.0 2.2 1 1 0 1 1 1 1 Septin NB-ARC PF00931.17 EGO28809.1 - 0.00011 21.2 0.0 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain G-alpha PF00503.15 EGO28809.1 - 0.00023 19.9 0.9 0.018 13.7 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit AAA_18 PF13238.1 EGO28809.1 - 0.00071 19.8 0.1 0.005 17.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.4 EGO28809.1 - 0.00083 18.8 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EGO28809.1 - 0.0014 18.9 0.2 0.0025 18.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_15 PF13175.1 EGO28809.1 - 0.0023 17.0 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EGO28809.1 - 0.0032 16.4 0.0 0.0055 15.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 EGO28809.1 - 0.0075 17.0 0.6 0.015 16.1 0.4 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGO28809.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EGO28809.1 - 0.0097 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Arf PF00025.16 EGO28809.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Pox_A32 PF04665.7 EGO28809.1 - 0.011 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EGO28809.1 - 0.025 14.0 0.1 0.29 10.5 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EGO28809.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Ras PF00071.17 EGO28809.1 - 0.034 13.5 0.0 0.076 12.4 0.0 1.6 1 1 0 1 1 1 0 Ras family AAA PF00004.24 EGO28809.1 - 0.037 14.2 0.5 0.049 13.8 0.4 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGO28809.1 - 0.043 13.4 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EGO28809.1 - 0.06 12.0 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 EGO28809.1 - 0.062 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGO28809.1 - 0.066 12.7 1.7 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EGO28809.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 EGO28809.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO28809.1 - 0.11 12.8 1.5 0.11 12.8 1.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO28809.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO28809.1 - 0.18 11.9 0.4 0.48 10.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO28809.1 - 0.3 11.0 1.3 0.57 10.1 0.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EGO28809.1 - 0.79 9.6 3.1 1.2 9.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain DUF1469 PF07332.6 EGO28810.1 - 1.6 8.5 5.6 1.6 8.5 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DinB_2 PF12867.2 EGO28811.1 - 1.2e-07 32.1 0.3 1.5e-07 31.8 0.2 1.1 1 0 0 1 1 1 1 DinB superfamily Aldo_ket_red PF00248.16 EGO28816.1 - 7.5e-35 120.1 0.0 8.5e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EGO28819.1 - 1.9e-39 135.3 44.1 3e-39 134.7 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Grp1_Fun34_YaaH PF01184.14 EGO28820.1 - 2.7e-51 173.8 17.8 3.3e-51 173.5 12.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mpv17_PMP22 PF04117.7 EGO28822.1 - 2.7e-22 78.1 0.6 4.3e-22 77.5 0.4 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Plasmodium_Vir PF05795.6 EGO28825.1 - 0.028 13.6 2.1 0.031 13.4 1.0 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF3698 PF12479.3 EGO28826.1 - 0.00081 19.4 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3698) ATG16 PF08614.6 EGO28826.1 - 0.037 13.8 1.2 0.043 13.6 0.9 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RepL PF05732.6 EGO28826.1 - 0.088 12.0 0.3 0.64 9.2 0.0 1.9 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) p450 PF00067.17 EGO28827.1 - 2.1e-31 108.9 0.0 2e-24 85.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 DUF930 PF06059.7 EGO28827.1 - 0.05 13.8 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) p450 PF00067.17 EGO28828.1 - 2.4e-39 135.1 0.0 3.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 YiiD_Cterm PF09500.5 EGO28828.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) Anoctamin PF04547.7 EGO28828.1 - 0.1 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel polyprenyl_synt PF00348.12 EGO28829.1 - 2.1e-38 131.6 0.0 2.6e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EGO28829.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain p450 PF00067.17 EGO28830.1 - 6.2e-73 245.8 0.0 8.9e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO28831.1 - 1.7e-54 185.1 0.0 6.5e-54 183.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 SAC3 PF12209.3 EGO28831.1 - 0.094 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain DUF4190 PF13828.1 EGO28831.1 - 0.12 11.9 0.8 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Prenyltrans_1 PF13243.1 EGO28832.1 - 6.1e-09 35.8 0.3 0.0015 18.5 0.1 3.5 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGO28832.1 - 1.5e-08 35.0 1.1 0.0025 18.2 0.0 4.0 3 1 1 4 4 4 2 Prenyltransferase-like Prenyltrans PF00432.16 EGO28832.1 - 0.0012 18.3 0.4 0.48 10.0 0.0 3.3 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat Terpene_synth_C PF03936.11 EGO28832.1 - 0.051 12.8 0.0 0.5 9.5 0.0 2.6 2 1 0 2 2 2 0 Terpene synthase family, metal binding domain SyrA PF11089.3 EGO28832.1 - 0.093 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Exopolysaccharide production repressor Mago-bind PF09282.5 EGO28832.1 - 0.11 12.1 0.2 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Mago binding Myb_DNA-bind_3 PF12776.2 EGO28834.1 - 0.00048 20.7 0.1 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO28834.1 - 0.048 13.8 0.8 0.17 12.0 0.0 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.9 EGO28834.1 - 0.1 12.8 1.3 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF573 p450 PF00067.17 EGO28837.1 - 7.4e-60 202.7 0.0 1.3e-44 152.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EGO28838.1 - 9.5e-32 110.1 0.0 9.5e-31 106.8 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EGO28839.1 - 3.7e-14 52.3 0.5 6.9e-14 51.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO28839.1 - 9e-06 25.5 0.0 2.9e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like BAALC_N PF06989.7 EGO28839.1 - 0.057 13.7 0.1 0.16 12.3 0.0 1.8 1 1 0 1 1 1 0 BAALC N-terminus adh_short PF00106.20 EGO28840.1 - 4.4e-18 65.7 0.0 6.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO28840.1 - 5.1e-08 32.7 0.1 7.7e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO28840.1 - 4.2e-05 23.6 0.8 0.00015 21.8 0.7 1.8 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO28840.1 - 4.4e-05 23.0 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGO28840.1 - 0.00065 19.8 0.1 0.001 19.2 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EGO28840.1 - 0.0046 16.7 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EGO28840.1 - 0.066 12.1 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.13 EGO28840.1 - 0.071 12.7 0.7 0.1 12.2 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EGO28840.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EGO28840.1 - 0.13 11.5 0.3 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_7 PF13241.1 EGO28840.1 - 0.23 11.7 0.7 0.35 11.1 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Transposase_21 PF02992.9 EGO28841.1 - 2.8e-05 23.3 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 LEA_6 PF10714.4 EGO28841.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Reo_sigmaC PF04582.7 EGO28842.1 - 0.0023 17.1 5.9 0.0033 16.6 4.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Peptidase_M9_N PF08453.5 EGO28842.1 - 0.029 13.7 6.7 0.015 14.6 2.4 2.0 1 1 1 2 2 2 0 Peptidase family M9 N-terminal V_ATPase_I PF01496.14 EGO28842.1 - 1.5 6.6 7.4 0.069 10.9 1.3 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EGO28842.1 - 1.5 8.6 12.5 0.31 10.8 3.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGO28842.1 - 2.9 7.4 8.2 2.2 7.8 3.8 2.0 2 0 0 2 2 2 0 IncA protein Prominin PF05478.6 EGO28842.1 - 4.2 4.7 12.0 8.8 3.7 7.9 1.6 1 1 1 2 2 2 0 Prominin Nnf1 PF03980.9 EGO28842.1 - 4.5 7.3 17.7 0.16 12.0 0.9 3.1 2 1 0 2 2 2 0 Nnf1 Mod_r PF07200.8 EGO28842.1 - 5.1 7.0 14.7 0.89 9.4 7.1 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF506 PF04720.7 EGO28842.1 - 6.3 6.3 9.8 0.074 12.6 1.2 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF506) Asp_protease_2 PF13650.1 EGO28843.1 - 9.1e-06 26.0 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO28843.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO28843.1 - 0.00051 19.9 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 EGO28844.1 - 1.4e-05 24.7 3.4 2.8e-05 23.7 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO28844.1 - 8e-05 22.3 5.5 8e-05 22.3 3.8 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO28844.1 - 0.29 10.6 3.6 0.52 9.8 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C2H2 PF00096.21 EGO28845.1 - 0.0006 20.0 13.3 0.025 14.9 0.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO28845.1 - 0.0019 18.4 12.8 0.4 11.1 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO28845.1 - 0.069 13.3 2.5 2.9 8.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-UBP PF02148.14 EGO28845.1 - 1.3 9.1 6.6 34 4.6 4.3 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2HC_2 PF13913.1 EGO28845.1 - 6.4 6.5 7.6 3.7 7.3 0.3 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF3595 PF12166.3 EGO28848.1 - 0.0014 17.5 0.0 0.0015 17.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) CoatB PF10389.4 EGO28849.1 - 0.16 11.8 0.1 8 6.4 0.0 3.6 4 0 0 4 4 4 0 Bacteriophage coat protein B NACHT PF05729.7 EGO28850.1 - 8.8e-05 22.2 0.0 0.00076 19.1 0.0 2.4 2 1 0 2 2 2 1 NACHT domain RPA_C PF08784.6 EGO28850.1 - 0.17 12.3 1.0 0.57 10.6 0.5 1.9 2 0 0 2 2 2 0 Replication protein A C terminal KAP_NTPase PF07693.9 EGO28850.1 - 0.3 10.0 1.8 1.8 7.4 0.7 2.0 1 1 1 2 2 2 0 KAP family P-loop domain gag-asp_proteas PF13975.1 EGO28852.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO28852.1 - 4.5e-06 27.0 0.0 5.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO28852.1 - 0.0014 18.5 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 EGO28853.1 - 4.3e-07 29.5 4.0 8.5e-07 28.6 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO28853.1 - 0.00068 19.6 0.2 0.002 18.1 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO28853.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein VanY PF02557.12 EGO28853.1 - 0.098 12.5 0.7 0.26 11.1 0.2 1.9 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MerR-DNA-bind PF09278.6 EGO28853.1 - 0.14 12.5 3.3 9 6.7 0.0 3.3 3 0 0 3 3 3 0 MerR, DNA binding Cauli_VI PF01693.11 EGO28856.1 - 0.42 10.6 4.4 0.61 10.1 3.0 1.3 1 0 0 1 1 1 0 Caulimovirus viroplasmin DUF1180 PF06679.7 EGO28858.1 - 0.013 15.3 11.9 0.093 12.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TRAP_alpha PF03896.11 EGO28858.1 - 0.077 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ABC_tran PF00005.22 EGO28860.1 - 6.2e-50 169.0 0.0 6.4e-30 104.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO28860.1 - 2.1e-45 155.3 29.6 6e-22 78.3 3.3 3.8 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 EGO28860.1 - 4.9e-10 39.8 0.1 0.012 15.5 0.0 4.5 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGO28860.1 - 3.7e-08 32.8 0.5 0.0047 16.1 0.1 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EGO28860.1 - 6.7e-08 31.7 0.0 0.01 14.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EGO28860.1 - 2.2e-06 27.2 0.2 0.035 13.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGO28860.1 - 5.3e-06 26.8 0.1 0.007 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO28860.1 - 8.7e-06 25.1 0.8 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO28860.1 - 0.00011 22.2 0.2 0.54 10.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGO28860.1 - 0.00038 20.6 0.8 6.2 6.9 0.0 4.2 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EGO28860.1 - 0.00038 20.1 0.1 0.07 12.8 0.0 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 EGO28860.1 - 0.00071 19.1 0.4 0.14 11.5 0.0 2.6 3 0 0 3 3 2 1 AAA-like domain DUF87 PF01935.12 EGO28860.1 - 0.0012 18.6 1.5 0.0013 18.5 0.1 1.7 2 0 0 2 2 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EGO28860.1 - 0.0075 17.0 0.2 3.7 8.4 0.1 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO28860.1 - 0.012 15.5 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGO28860.1 - 0.012 15.0 0.3 0.6 9.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EGO28860.1 - 0.014 15.8 0.0 8 6.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EGO28860.1 - 0.014 15.1 0.0 0.59 9.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EGO28860.1 - 0.015 14.9 0.4 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGO28860.1 - 0.018 14.7 0.0 0.97 9.0 0.0 2.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EGO28860.1 - 0.025 14.9 0.1 8.9 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGO28860.1 - 0.044 12.6 0.5 0.58 8.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain CcmD PF04995.9 EGO28860.1 - 0.047 13.4 0.1 0.047 13.4 0.1 3.1 3 0 0 3 3 1 0 Heme exporter protein D (CcmD) Zeta_toxin PF06414.7 EGO28860.1 - 0.058 12.4 0.2 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EGO28860.1 - 0.069 13.0 0.0 4.6 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EGO28860.1 - 0.078 12.6 0.2 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EGO28860.1 - 0.12 11.6 0.2 14 4.8 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein DUF258 PF03193.11 EGO28860.1 - 0.12 11.5 0.2 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGO28860.1 - 0.14 11.8 0.1 5.1 6.8 0.0 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGO28860.1 - 0.17 11.7 0.1 25 4.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGO28860.1 - 0.31 9.9 0.1 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EGO28860.1 - 0.49 9.8 1.4 10 5.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain F_bP_aldolase PF01116.15 EGO28862.1 - 1.6e-68 230.9 0.0 1.8e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II 7TM_GPCR_Srh PF10318.4 EGO28864.1 - 0.0067 15.2 0.2 0.0067 15.2 0.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh MARVEL PF01284.18 EGO28865.1 - 9.5e-06 25.4 11.7 1.2e-05 25.2 7.6 1.5 1 1 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EGO28865.1 - 0.0076 15.8 4.7 0.69 9.4 0.3 2.2 1 1 0 2 2 2 2 SUR7/PalI family TctB PF07331.6 EGO28865.1 - 0.0096 15.5 11.2 0.06 13.0 7.5 2.1 1 1 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF4079 PF13301.1 EGO28865.1 - 0.02 14.8 5.1 0.07 13.1 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2583 PF10762.4 EGO28865.1 - 0.57 10.3 3.0 0.67 10.1 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2583) WBP-1 PF11669.3 EGO28865.1 - 4.9 7.3 8.5 12 6.0 2.6 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 MgtE PF01769.11 EGO28865.1 - 7.1 6.9 7.7 3.4 7.9 0.3 2.9 2 1 1 3 3 3 0 Divalent cation transporter RAI1 PF08652.6 EGO28866.1 - 2e-10 40.2 0.0 3.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Pkinase PF00069.20 EGO28868.1 - 1.5e-12 47.2 0.1 1.6e-12 47.1 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28868.1 - 0.00057 19.0 0.5 0.0012 17.9 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 EGO28868.1 - 0.11 11.5 0.2 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_3 PF12776.2 EGO28870.1 - 7.8e-06 26.4 0.2 1.3e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO28870.1 - 6e-05 23.0 0.1 8.7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Methyltransf_22 PF13383.1 EGO28872.1 - 5.3e-28 98.1 0.0 6.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EGO28872.1 - 2.1e-08 34.2 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain O-antigen_lig PF13425.1 EGO28872.1 - 0.023 14.6 0.2 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Pex14_N PF04695.8 EGO28873.1 - 0.44 10.5 8.3 0.54 10.3 5.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lamp PF01299.12 EGO28873.1 - 1.4 7.9 9.2 1.6 7.7 6.4 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Dicty_REP PF05086.7 EGO28873.1 - 2.6 5.6 6.3 2.9 5.5 4.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein KAR9 PF08580.5 EGO28873.1 - 4.7 5.3 9.6 4.6 5.3 6.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Shisa PF13908.1 EGO28873.1 - 6.7 6.8 7.9 7.3 6.7 5.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CytochromB561_N PF09786.4 EGO28873.1 - 9.5 4.5 9.6 9.4 4.5 6.7 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2012 PF09430.5 EGO28875.1 - 7.5e-21 74.2 0.1 1.4e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EGO28875.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SH2 PF00017.19 EGO28875.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 SH2 domain DUF4405 PF14358.1 EGO28875.1 - 2.1 8.5 4.6 4.6 7.4 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) zf-CCHC_4 PF14392.1 EGO28878.1 - 0.021 14.4 2.0 0.043 13.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle CD24 PF14984.1 EGO28878.1 - 1.6 8.5 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein F-box-like PF12937.2 EGO28882.1 - 3e-05 23.6 0.1 3e-05 23.6 0.0 4.3 3 1 1 4 4 4 2 F-box-like F-box-like PF12937.2 EGO28883.1 - 4.2e-08 32.7 1.0 1.1e-07 31.4 0.7 1.8 1 0 0 1 1 1 1 F-box-like DUF3808 PF10300.4 EGO28885.1 - 7.7e-72 242.3 0.1 1.2e-71 241.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EGO28885.1 - 5.8e-05 22.6 5.5 0.0096 15.5 0.5 4.5 4 1 0 4 4 4 1 TPR repeat TPR_12 PF13424.1 EGO28885.1 - 8.5e-05 22.4 1.1 10 6.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO28885.1 - 0.00081 19.1 7.0 1.6 8.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO28885.1 - 0.0054 17.3 0.4 0.29 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGO28885.1 - 0.0067 16.7 1.4 0.19 12.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO28885.1 - 0.018 14.8 0.3 10 6.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO28885.1 - 0.047 14.3 1.5 2.8 8.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO28885.1 - 0.23 11.1 4.0 11 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 EGO28886.1 - 4.8e-14 52.4 0.0 5.6e-10 39.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) zf-MYND PF01753.13 EGO28886.1 - 8.6e-11 41.5 18.4 1.5e-10 40.7 12.8 1.4 1 0 0 1 1 1 1 MYND finger Ank PF00023.25 EGO28886.1 - 3.3e-09 36.0 0.7 0.0004 20.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGO28886.1 - 2.1e-08 34.4 0.1 0.0026 18.2 0.0 3.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO28886.1 - 4.9e-06 26.5 0.1 0.00085 19.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO28886.1 - 5.5e-06 26.1 0.0 0.0057 16.7 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat DUF2256 PF10013.4 EGO28886.1 - 0.0026 17.4 4.0 0.0047 16.6 2.8 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-HIT PF04438.11 EGO28886.1 - 0.39 10.3 8.5 0.71 9.5 5.9 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.1 EGO28886.1 - 1.1 9.1 8.2 3.4 7.5 5.7 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Gti1_Pac2 PF09729.4 EGO28889.1 - 2.5e-28 99.0 0.2 5.5e-26 91.4 0.1 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family F-box-like PF12937.2 EGO28892.1 - 6.4e-08 32.2 0.9 2.2e-07 30.5 0.6 2.0 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 EGO28892.1 - 0.018 15.4 0.3 0.15 12.6 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat UBN2_3 PF14244.1 EGO28899.1 - 6.2e-06 25.8 0.0 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO28899.1 - 1.4e-05 24.3 0.1 2.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EGO28899.1 - 2e-05 24.1 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO28899.1 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ATG11 PF10377.4 EGO28901.1 - 0.028 14.2 0.2 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 11 PXA PF02194.10 EGO28902.1 - 3.7e-26 91.8 0.6 6.9e-26 90.9 0.4 1.5 1 0 0 1 1 1 1 PXA domain Chromo PF00385.19 EGO28904.1 - 2.2e-13 49.6 0.4 5.5e-13 48.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGO28904.1 - 0.0019 17.8 0.9 0.0019 17.8 0.6 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Myb_DNA-bind_3 PF12776.2 EGO28907.1 - 0.001 19.6 0.3 0.0023 18.5 0.1 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO28907.1 - 0.018 15.1 0.3 0.037 14.1 0.2 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nuc_rec_co-act PF08815.5 EGO28907.1 - 0.06 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator NPCBM PF08305.6 EGO28907.1 - 0.079 12.9 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NPCBM/NEW2 domain BLVR PF06375.6 EGO28911.1 - 0.028 14.2 7.1 0.034 13.9 4.9 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ABC_tran PF00005.22 EGO28912.1 - 1.7e-50 170.8 0.0 1.2e-29 103.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO28912.1 - 1.8e-46 158.7 20.1 2.6e-19 69.7 2.3 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EGO28912.1 - 1.5e-10 41.5 0.1 0.013 15.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGO28912.1 - 7.4e-08 31.8 2.1 0.0028 16.9 1.1 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EGO28912.1 - 2.3e-07 30.0 0.3 0.0029 16.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EGO28912.1 - 6.7e-07 28.9 0.0 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO28912.1 - 2.8e-06 26.7 0.2 0.13 11.7 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO28912.1 - 4.4e-06 27.1 0.1 0.0014 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO28912.1 - 0.00051 20.2 0.6 6.2 6.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EGO28912.1 - 0.002 18.1 3.0 2.1 8.3 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain Arch_ATPase PF01637.13 EGO28912.1 - 0.0038 16.9 0.0 0.064 12.9 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EGO28912.1 - 0.0069 16.6 0.2 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGO28912.1 - 0.0086 15.9 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_19 PF13245.1 EGO28912.1 - 0.012 15.3 0.2 0.95 9.2 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EGO28912.1 - 0.017 14.5 0.0 7.5 5.9 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EGO28912.1 - 0.021 15.6 0.1 8.1 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGO28912.1 - 0.021 14.2 0.2 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain RseC_MucC PF04246.7 EGO28912.1 - 0.032 13.7 0.1 0.032 13.7 0.1 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Dynamin_N PF00350.18 EGO28912.1 - 0.037 13.8 0.1 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 EGO28912.1 - 0.04 13.8 0.7 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGO28912.1 - 0.046 12.8 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 EGO28912.1 - 0.089 13.2 0.2 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EGO28912.1 - 0.098 12.3 0.3 8.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGO28912.1 - 0.14 12.0 0.2 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EGO28912.1 - 0.19 10.9 0.2 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 EGO28912.1 - 0.23 10.9 1.2 3.5 7.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGO28912.1 - 0.39 10.5 2.9 18 5.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGO28912.1 - 0.5 10.0 1.9 3.9 7.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGO28912.1 - 2.1 7.9 4.3 6.6 6.3 0.0 2.8 3 0 0 3 3 2 0 NACHT domain PepSY_TM_2 PF13703.1 EGO28915.1 - 0.61 10.3 6.1 0.23 11.6 0.7 2.2 1 1 1 2 2 2 0 PepSY-associated TM helix 4HBT_2 PF13279.1 EGO28919.1 - 5.4e-10 39.7 0.0 9.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase_Tyr PF07714.12 EGO28920.1 - 3.4e-37 127.9 0.0 4.8e-35 120.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO28920.1 - 3.9e-30 104.8 0.0 5.2e-17 61.8 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Kdo PF06293.9 EGO28920.1 - 0.018 14.1 0.0 0.044 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1546 PF07571.8 EGO28922.1 - 0.027 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Glyco_hydro_3 PF00933.16 EGO28923.1 - 1e-76 257.7 0.2 1.5e-76 257.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO28923.1 - 1.3e-57 194.9 0.2 4.8e-57 193.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO28923.1 - 8.3e-19 67.3 0.0 1.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 EGO28924.1 - 1.2e-78 264.1 0.1 1.7e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO28924.1 - 4e-56 190.0 0.1 1.2e-55 188.5 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO28924.1 - 1.6e-16 59.9 0.0 3.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pheromone PF08015.6 EGO28925.1 - 0.0078 17.0 1.0 0.15 12.9 0.7 2.0 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EGO28926.1 - 0.0031 18.3 2.8 0.095 13.5 1.9 2.1 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EGO28927.1 - 3.4e-07 30.9 1.6 5.3e-07 30.3 1.1 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EGO28928.1 - 6.4e-05 23.7 0.7 0.00029 21.6 0.5 1.8 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EGO28929.1 - 0.017 15.9 1.5 0.12 13.2 1.1 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone ResIII PF04851.10 EGO28930.1 - 3.9e-19 69.1 0.0 7.2e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO28930.1 - 1.6e-15 56.6 0.0 5.2e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO28930.1 - 4.3e-15 55.6 0.0 7.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EGO28930.1 - 1.3e-05 24.1 0.0 2.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EGO28930.1 - 0.0033 16.4 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.10 EGO28930.1 - 0.022 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.1 EGO28930.1 - 0.029 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 EGO28930.1 - 0.054 13.4 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain UBN2_2 PF14227.1 EGO28931.1 - 5.8e-05 22.6 0.1 0.0001 21.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Orthopox_F8 PF05886.6 EGO28931.1 - 3.9 7.3 7.6 23 4.9 0.3 3.0 3 0 0 3 3 3 0 Orthopoxvirus F8 protein eIF3g PF12353.3 EGO28935.1 - 3e-42 143.5 1.8 4.2e-42 143.0 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EGO28935.1 - 2.5e-18 65.4 0.1 5.5e-18 64.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO28935.1 - 3.1e-16 59.0 0.0 6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO28935.1 - 4.9e-08 32.7 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO28935.1 - 0.029 14.2 0.3 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif F-box-like PF12937.2 EGO28937.1 - 0.011 15.4 0.2 0.066 12.9 0.1 2.4 1 1 0 1 1 1 0 F-box-like AdoMet_MTase PF07757.8 EGO28938.1 - 5.9e-33 113.3 0.0 1.9e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EGO28938.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGO28938.1 - 0.029 14.0 0.0 0.067 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGO28938.1 - 0.071 12.6 0.0 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGO28938.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCI PF01399.22 EGO28939.1 - 0.00013 22.2 0.0 0.00035 20.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 EGO28939.1 - 0.058 13.2 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FMO-like PF00743.14 EGO28940.1 - 2.4e-25 88.7 0.0 2.9e-15 55.4 0.0 3.3 4 0 0 4 4 4 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO28940.1 - 5.4e-12 46.2 0.0 7.8e-11 42.4 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO28940.1 - 6.2e-07 28.6 0.0 5.4e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO28940.1 - 6.4e-07 29.4 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO28940.1 - 1e-06 28.6 0.0 5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO28940.1 - 0.00038 20.2 0.0 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGO28940.1 - 0.0013 17.9 0.0 0.0045 16.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family STE3 PF02076.10 EGO28940.1 - 0.0013 17.8 0.7 0.002 17.2 0.5 1.2 1 0 0 1 1 1 1 Pheromone A receptor FAD_binding_3 PF01494.14 EGO28940.1 - 0.025 13.6 0.0 0.077 12.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EGO28940.1 - 0.039 12.4 0.0 0.13 10.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FMN_red PF03358.10 EGO28940.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DAO PF01266.19 EGO28940.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.17 EGO28941.1 - 1.5e-63 214.9 0.0 6.4e-63 212.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.14 EGO28942.1 - 7e-25 87.2 0.0 7.5e-15 54.1 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO28942.1 - 5e-11 43.0 0.0 7.3e-08 32.7 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO28942.1 - 4e-08 33.3 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO28942.1 - 7.5e-07 28.3 0.0 5.7e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO28942.1 - 3.2e-06 27.0 0.0 1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO28942.1 - 0.0019 17.3 0.0 0.0086 15.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EGO28942.1 - 0.0096 15.6 0.1 0.15 11.8 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding FMN_red PF03358.10 EGO28942.1 - 0.047 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase PGI PF00342.14 EGO28943.1 - 3.9e-178 592.8 2.4 4e-140 467.4 0.1 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase Bombolitin PF08096.6 EGO28943.1 - 7.6 6.8 6.6 76 3.6 0.2 3.4 2 1 1 3 3 3 0 Bombolitin family DUF3602 PF12223.3 EGO28947.1 - 4.9e-23 81.3 36.9 0.00018 21.7 1.6 6.2 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) DUF972 PF06156.8 EGO28952.1 - 0.0059 16.9 0.7 0.013 15.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Microtub_assoc PF07989.6 EGO28952.1 - 0.035 13.9 1.4 0.073 12.9 1.0 1.5 1 0 0 1 1 1 0 Microtubule associated bZIP_1 PF00170.16 EGO28952.1 - 0.05 13.5 3.1 0.15 12.0 2.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EGO28952.1 - 0.088 12.2 3.6 0.21 11.1 2.5 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 EGO28952.1 - 0.31 10.8 3.1 0.64 9.8 2.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EGO28952.1 - 1.1 8.8 7.1 2.4 7.7 4.9 1.5 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EGO28955.1 - 9e-17 60.8 39.2 5.3e-11 41.8 11.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.20 EGO28955.1 - 1e-08 34.6 0.1 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO28955.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EGO28955.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.20 EGO28956.1 - 9.3e-16 58.1 0.0 4.8e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGO28956.1 - 4.8e-07 29.6 0.0 1.4e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EGO28956.1 - 0.0012 18.6 0.0 0.067 12.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EGO28956.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGO28956.1 - 0.0085 15.0 0.0 0.071 11.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGO28956.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO28957.1 - 6.1e-19 68.5 0.0 7.5e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO28957.1 - 6.3e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO28957.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGO28957.1 - 0.02 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EGO28957.1 - 0.029 13.2 0.0 0.36 9.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1858 PF08984.6 EGO28957.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) FHA PF00498.21 EGO28959.1 - 3.4e-17 62.3 0.1 7.3e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Cys_Met_Meta_PP PF01053.15 EGO28960.1 - 9.1e-128 425.8 0.0 2.5e-98 328.8 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGO28960.1 - 0.00023 20.2 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EGO28960.1 - 0.0011 17.3 0.0 0.0014 17.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Ni_hydr_CYTB PF01292.15 EGO28961.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 PAPA-1 PF04795.7 EGO28962.1 - 2.5e-13 50.5 15.5 3.5e-13 50.0 8.1 2.5 2 1 0 2 2 2 1 PAPA-1-like conserved region Rotamase_2 PF13145.1 EGO28962.1 - 0.019 15.6 0.6 0.027 15.0 0.4 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Peptidase_S49_N PF08496.5 EGO28962.1 - 0.66 9.7 3.9 0.91 9.3 2.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ferritin_2 PF13668.1 EGO28963.1 - 9e-43 145.5 1.0 9e-43 145.5 0.7 1.8 2 0 0 2 2 2 1 Ferritin-like domain Ferritin_2 PF13668.1 EGO28964.1 - 1.3e-45 154.7 0.6 2.2e-45 153.9 0.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 EGO28965.1 - 1.6e-15 57.2 0.1 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain HpcH_HpaI PF03328.9 EGO28966.1 - 1.5e-33 115.5 0.0 1.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Herpes_TAF50 PF03326.8 EGO28966.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF3413 PF11893.3 EGO28969.1 - 2.5 6.9 12.8 0.35 9.7 1.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3413) DUF4305 PF14146.1 EGO28970.1 - 0.25 11.1 2.8 0.32 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) p450 PF00067.17 EGO28971.1 - 4e-64 216.8 0.0 9.9e-64 215.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ammonium_transp PF00909.16 EGO28974.1 - 8.4e-120 399.8 20.5 9.6e-120 399.6 14.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_43 PF04616.9 EGO28975.1 - 9.6e-36 123.3 0.1 1.1e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR_2 PF13088.1 EGO28975.1 - 0.0093 15.2 0.1 0.87 8.8 0.0 2.4 1 1 0 2 2 2 1 BNR repeat-like domain Filamin PF00630.14 EGO28975.1 - 0.035 14.6 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 Filamin/ABP280 repeat Dmrt1 PF12374.3 EGO28975.1 - 0.43 10.9 4.2 0.31 11.4 0.2 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Gln-synt_C PF00120.19 EGO28976.1 - 3.7e-54 183.6 0.0 4.8e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Indigoidine_A PF04227.7 EGO28980.1 - 1.4e-119 398.7 0.4 5e-119 396.8 0.1 1.9 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 EGO28980.1 - 5.5e-16 58.5 0.0 2.5e-07 30.1 0.0 2.5 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Phage_B PF02304.10 EGO28987.1 - 0.0065 16.7 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Scaffold protein B DUF2162 PF09930.4 EGO28988.1 - 0.39 9.8 2.2 0.67 9.0 1.5 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) TTL PF03133.10 EGO28992.1 - 3.8e-46 157.3 0.0 4.6e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EGO28992.1 - 0.0015 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Apc13p PF05839.6 EGO29001.1 - 0.047 13.6 1.7 0.047 13.6 1.2 1.8 1 1 1 2 2 2 0 Apc13p protein Mod_r PF07200.8 EGO29003.1 - 0.081 12.8 1.0 0.1 12.5 0.7 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MRP-S32 PF10210.4 EGO29004.1 - 0.077 13.3 0.0 0.34 11.2 0.0 1.9 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S32 RTC4 PF14474.1 EGO29005.1 - 1.7e-08 34.4 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain IspD PF01128.14 EGO29006.1 - 0.043 13.3 0.0 0.045 13.2 0.0 1.0 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Cnd2 PF05786.9 EGO29007.1 - 0.011 14.2 2.2 0.013 14.0 1.5 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF4218 PF13960.1 EGO29008.1 - 0.01 15.2 0.1 0.041 13.3 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4218) YhdB PF14148.1 EGO29008.1 - 0.47 10.2 4.6 0.29 10.9 0.3 2.4 2 1 0 2 2 2 0 YhdB-like protein DUF2082 PF09855.4 EGO29012.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-IS66 PF13005.2 EGO29012.1 - 0.87 9.6 5.8 14 5.7 4.0 2.2 1 1 0 1 1 1 0 zinc-finger binding domain of transposase IS66 DUF605 PF04652.11 EGO29014.1 - 7.5 5.8 7.6 7.8 5.7 5.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF4098 PF13345.1 EGO29015.1 - 0.07 13.0 0.6 17 5.4 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4098) Meth_synt_2 PF01717.13 EGO29016.1 - 1.9e-24 86.2 0.0 6.8e-24 84.4 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGO29016.1 - 2.4e-07 30.3 0.0 0.13 11.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain CRT-like PF08627.5 EGO29020.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 CRT-like ABC_sub_bind PF04392.7 EGO29020.1 - 0.13 11.1 0.0 4.7 6.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter substrate binding protein Aldose_epim PF01263.15 EGO29024.1 - 3.9e-27 95.1 0.1 4.5e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3816 PF12822.2 EGO29025.1 - 0.067 13.0 5.8 0.13 12.1 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF1275 PF06912.6 EGO29027.1 - 2.2e-23 82.5 15.3 3.1e-23 82.0 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3084 PF11283.3 EGO29027.1 - 0.17 11.7 1.3 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) DUF2264 PF10022.4 EGO29031.1 - 1.3e-133 445.1 0.1 1.5e-133 444.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BNR PF02012.15 EGO29031.1 - 0.07 12.9 0.1 0.29 11.0 0.1 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat p450 PF00067.17 EGO29033.1 - 0.0022 16.6 0.0 0.0025 16.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EGO29034.1 - 7.3e-28 97.1 0.3 1.8e-27 95.8 0.2 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO29034.1 - 2.9e-22 78.8 0.0 3.7e-21 75.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EGO29034.1 - 4.1e-11 42.7 0.0 8.5e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO29034.1 - 0.00056 18.7 0.0 0.29 9.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO29034.1 - 0.0063 16.5 0.1 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding PP-binding PF00550.20 EGO29034.1 - 0.039 14.2 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site SHR3_chaperone PF08229.6 EGO29035.1 - 0.53 9.2 4.8 0.11 11.4 0.7 1.8 2 0 0 2 2 2 0 ER membrane protein SH3 zf-CCHC_3 PF13917.1 EGO29036.1 - 4.9e-06 26.1 3.4 7.8e-06 25.5 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO29036.1 - 1.8e-05 24.4 5.5 2.7e-05 23.8 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO29036.1 - 0.17 11.3 4.3 0.28 10.7 3.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EGO29038.1 - 0.016 15.0 0.6 0.032 14.1 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 EGO29039.1 - 1.3e-06 28.3 0.0 1.5e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO29039.1 - 1.4e-05 25.4 0.0 1.7e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO29039.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-ribbon_3 PF13248.1 EGO29042.1 - 0.0065 15.6 3.6 0.58 9.4 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 EGO29042.1 - 0.013 15.0 2.0 0.016 14.7 1.4 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C4pol PF14260.1 EGO29042.1 - 0.058 13.3 1.8 0.087 12.8 1.3 1.3 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC_3 PF13917.1 EGO29042.1 - 0.075 12.7 4.5 0.13 12.0 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DZR PF12773.2 EGO29042.1 - 0.15 11.9 6.6 0.39 10.5 4.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.19 EGO29042.1 - 2.1 8.3 5.9 10 6.0 4.1 1.9 1 1 0 1 1 1 0 B-box zinc finger zf-DHHC PF01529.15 EGO29042.1 - 4.6 6.6 6.9 7.4 5.9 4.8 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.1 EGO29042.1 - 6.8 6.3 8.2 1 8.9 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DDE_Tnp_ISAZ013 PF07592.6 EGO29045.1 - 0.035 12.8 0.2 0.056 12.1 0.2 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Indigoidine_A PF04227.7 EGO29048.1 - 1.2e-107 359.5 1.1 1.6e-107 359.1 0.2 1.6 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 EGO29048.1 - 2.1e-15 56.6 0.0 2.6e-07 30.0 0.0 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase HALZ PF02183.13 EGO29050.1 - 0.087 12.5 1.2 0.19 11.4 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EGO29050.1 - 0.27 11.2 1.7 0.54 10.2 1.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EGO29050.1 - 0.37 10.3 2.6 0.99 8.9 1.8 1.7 1 0 0 1 1 1 0 Septum formation initiator WSC PF01822.14 EGO29055.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 WSC domain GnHR_trans PF12369.3 EGO29055.1 - 0.08 13.3 0.3 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region PDDEXK_1 PF12705.2 EGO29059.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Retrotrans_gag PF03732.12 EGO29060.1 - 4.1e-06 26.7 0.1 4.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Zn_Tnp_IS91 PF14319.1 EGO29066.1 - 0.12 11.9 2.1 0.24 10.9 1.4 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_3 PF13917.1 EGO29066.1 - 0.28 10.9 4.6 0.69 9.6 3.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-ribbon_3 PF13248.1 EGO29066.1 - 0.89 8.8 6.4 3 7.1 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGO29066.1 - 2.2 8.1 7.8 0.37 10.6 2.4 2.0 2 0 0 2 2 2 0 Double zinc ribbon MASE2 PF05230.6 EGO29068.1 - 0.076 12.9 0.1 0.48 10.4 0.0 2.2 3 0 0 3 3 3 0 MASE2 domain Citrate_synt PF00285.16 EGO29072.1 - 5.8e-18 64.7 0.0 5.2e-16 58.3 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EGO29072.1 - 5.9e-16 58.4 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EGO29072.1 - 1.4e-13 51.1 0.0 3.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 EGO29072.1 - 2.5e-07 30.2 0.0 4.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EGO29072.1 - 7.1e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain STE3 PF02076.10 EGO29073.1 - 1.3e-71 240.9 18.5 1.5e-71 240.7 12.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor BTB PF00651.26 EGO29074.1 - 5.5e-07 29.5 0.0 9.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rad60-SLD_2 PF13881.1 EGO29076.1 - 2.4e-14 53.1 0.0 2.2e-13 50.0 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGO29076.1 - 7.5e-06 25.2 0.0 3e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Adeno_PVIII PF01310.13 EGO29077.1 - 0.12 12.1 0.2 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII DnaJ PF00226.26 EGO29081.1 - 8.3e-06 25.4 0.2 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain VGLL4 PF15245.1 EGO29081.1 - 0.004 17.0 3.4 0.0058 16.4 2.4 1.3 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 Pkinase PF00069.20 EGO29082.1 - 7.2e-31 107.2 0.0 2e-30 105.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29082.1 - 2.4e-14 53.0 0.0 4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EGO29084.1 - 1.9e-19 69.7 0.0 2.2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO29084.1 - 2.6e-17 62.8 0.1 8.2e-07 29.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO29084.1 - 2.4e-16 59.3 1.3 0.00011 22.3 0.0 3.7 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGO29084.1 - 4.6e-16 57.7 0.0 0.00024 20.7 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EGO29084.1 - 9e-13 47.1 0.3 0.034 14.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Neil1-DNA_bind PF09292.5 EGO29084.1 - 0.13 12.0 0.2 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind EHN PF06441.7 EGO29085.1 - 4.8e-33 113.4 0.4 5.9e-32 109.9 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGO29085.1 - 1.4e-09 38.1 1.4 5.5e-09 36.2 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO29085.1 - 0.0069 15.9 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Arylsulfotrans PF05935.6 EGO29086.1 - 0.04 12.4 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) TGT PF01702.13 EGO29089.1 - 3.3e-25 88.7 0.0 5e-20 71.8 0.0 3.0 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase Dimer_Tnp_hAT PF05699.9 EGO29091.1 - 0.00013 21.5 0.4 0.00022 20.7 0.3 1.5 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Rhomboid_SP PF12595.3 EGO29091.1 - 0.079 12.5 0.0 0.51 9.8 0.0 2.0 1 1 1 2 2 2 0 Rhomboid serine protease PepSY_TM_1 PF13172.1 EGO29092.1 - 5 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO29093.1 - 2.8e-08 33.2 1.1 4e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO29093.1 - 0.077 12.6 0.5 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO29093.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Kinetochor_Ybp2 PF08568.5 EGO29094.1 - 1.5e-15 56.4 0.2 7.6e-15 54.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin Calici_PP_N PF08405.6 EGO29094.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral polyprotein N-terminal RIO1 PF01163.17 EGO29095.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Transp_cyt_pur PF02133.10 EGO29096.1 - 1.6e-38 132.4 30.6 7.1e-38 130.2 21.2 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mob1_phocein PF03637.12 EGO29097.1 - 9.4e-26 90.5 0.1 4.1e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Mob1/phocein family PGAP1 PF07819.8 EGO29099.1 - 2.4e-08 33.8 0.0 5e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO29099.1 - 3.1e-08 33.8 0.0 4.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO29099.1 - 3.3e-08 33.3 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO29099.1 - 2.5e-06 27.2 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EGO29099.1 - 8.6e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EGO29099.1 - 0.00016 21.9 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.7 EGO29099.1 - 0.00047 19.0 0.2 0.002 16.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF676 PF05057.9 EGO29099.1 - 0.0028 16.9 0.6 0.0039 16.5 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 EGO29099.1 - 0.005 16.5 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 EGO29099.1 - 0.033 13.2 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EGO29099.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.6 1 1 1 2 2 2 0 Putative esterase DUF2235 PF09994.4 EGO29099.1 - 0.07 12.4 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DinI PF06183.8 EGO29099.1 - 0.097 12.6 0.1 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 DinI-like family LCAT PF02450.10 EGO29099.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Acetyltransf_8 PF13523.1 EGO29100.1 - 1e-32 113.1 0.1 1.6e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO29100.1 - 0.00025 21.2 0.1 0.00059 20.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TT_ORF2 PF02957.10 EGO29101.1 - 0.9 10.2 5.1 1.1 10.0 3.6 1.2 1 0 0 1 1 1 0 TT viral ORF2 FRQ PF09421.5 EGO29101.1 - 6.2 4.4 12.7 6.7 4.3 8.8 1.0 1 0 0 1 1 1 0 Frequency clock protein R3H PF01424.17 EGO29102.1 - 2e-07 30.5 0.1 3.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EGO29102.1 - 2.4e-07 30.5 35.1 8.2e-07 28.8 6.8 14.3 15 0 0 15 15 15 6 NF-X1 type zinc finger NYD-SP28 PF14772.1 EGO29103.1 - 0.16 12.1 0.2 0.16 12.1 0.1 2.3 2 0 0 2 2 2 0 Sperm tail Caudo_TAP PF02413.12 EGO29103.1 - 0.16 12.1 3.1 2.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein F-box-like PF12937.2 EGO29108.1 - 0.074 12.7 1.1 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.2 EGO29108.1 - 0.9 9.2 11.3 6.3 6.5 0.0 5.2 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) TFIIA_gamma_N PF02268.11 EGO29109.1 - 3.6e-26 90.5 0.2 5.5e-26 89.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EGO29109.1 - 8.9e-24 83.0 0.1 1.2e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.9 EGO29109.1 - 0.089 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Scytalone dehydratase Amidase PF01425.16 EGO29110.1 - 7.1e-91 305.2 0.0 8.4e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Chlam_OMP6 PF03504.8 EGO29112.1 - 0.018 15.2 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 TFIIE_alpha PF02002.12 EGO29112.1 - 0.042 13.3 0.0 0.061 12.8 0.0 1.3 1 1 0 1 1 1 0 TFIIE alpha subunit CAAD PF14159.1 EGO29113.1 - 1.3 8.6 3.8 0.5 10.0 0.5 1.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Herpes_US9 PF06072.6 EGO29113.1 - 2.4 8.0 4.4 0.9 9.4 0.9 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Amastin PF07344.6 EGO29114.1 - 0.00096 18.7 1.1 0.0015 18.2 0.8 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein RRM_1 PF00076.17 EGO29115.1 - 7.2e-19 67.2 0.0 1.7e-10 40.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO29115.1 - 6.9e-16 57.9 0.0 8.6e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO29115.1 - 2e-06 27.5 0.0 0.0021 17.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI-anchored PF10342.4 EGO29117.1 - 1.8e-05 25.1 2.4 1.8e-05 25.1 1.7 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4307 PF14155.1 EGO29118.1 - 0.072 12.8 1.7 0.076 12.8 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) AA_permease_2 PF13520.1 EGO29119.1 - 9.4e-76 255.0 45.0 1.2e-75 254.6 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO29119.1 - 5.5e-15 54.6 38.6 8.5e-15 54.0 26.8 1.3 1 0 0 1 1 1 1 Amino acid permease Pro_isomerase PF00160.16 EGO29120.1 - 2.3e-41 141.5 1.4 2.6e-41 141.4 1.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4098 PF13345.1 EGO29121.1 - 1.9e-05 24.5 0.1 0.21 11.5 0.0 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF4098) DUF4098 PF13345.1 EGO29123.1 - 5.6e-05 23.0 8.3 0.012 15.5 0.0 4.4 3 2 0 3 3 3 2 Domain of unknown function (DUF4098) Ribosomal_L18ae PF01775.12 EGO29125.1 - 4.7e-60 200.9 0.4 5.6e-60 200.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain JAB PF01398.16 EGO29126.1 - 2.6e-28 98.0 0.1 5.2e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGO29126.1 - 6.8e-06 25.5 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4404 PF14357.1 EGO29126.1 - 0.046 14.1 0.4 0.092 13.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Oxidored-like PF09791.4 EGO29127.1 - 4.1e-14 51.7 0.8 8.1e-14 50.7 0.5 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal COesterase PF00135.23 EGO29128.1 - 4.7e-97 325.9 0.0 5.2e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO29128.1 - 9.5e-06 25.3 4.1 4.2e-05 23.2 1.7 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold EKR PF10371.4 EGO29128.1 - 0.00055 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function Abhydrolase_5 PF12695.2 EGO29128.1 - 0.049 13.3 0.6 0.095 12.4 0.4 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family FHA PF00498.21 EGO29129.1 - 2.2e-11 43.7 0.0 3.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Ribonucleas_3_3 PF14622.1 EGO29130.1 - 1.2e-15 57.6 0.1 5e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGO29130.1 - 0.03 14.7 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease III domain BTB PF00651.26 EGO29131.1 - 9.2e-09 35.2 0.1 2.2e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EGO29132.1 - 5.1e-09 36.0 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Amidase PF01425.16 EGO29133.1 - 1.1e-81 274.9 0.0 2.8e-71 240.6 0.0 2.7 2 1 0 2 2 2 2 Amidase Amidase PF01425.16 EGO29134.1 - 4.4e-92 309.2 0.0 5.1e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Amidase SET PF00856.23 EGO29135.1 - 8.5e-10 39.1 0.0 3.1e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EGO29135.1 - 9.5e-07 28.5 11.6 9.5e-07 28.5 8.0 3.1 2 1 0 2 2 2 1 MYND finger CH PF00307.26 EGO29136.1 - 1.3e-68 227.8 0.0 3.5e-20 72.0 0.0 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGO29136.1 - 1.6e-07 30.8 0.0 0.93 9.1 0.0 4.5 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 EGO29136.1 - 0.046 13.8 0.1 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair GST_C PF00043.20 EGO29137.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO29137.1 - 0.06 13.2 0.2 0.18 11.7 0.1 1.6 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.16 EGO29138.1 - 1.5e-26 93.0 0.1 2.3e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel His_Phos_1 PF00300.17 EGO29140.1 - 1.4e-22 80.4 0.0 1.8e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Shisa PF13908.1 EGO29141.1 - 0.18 12.0 2.5 0.2 11.8 1.8 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Prominin PF05478.6 EGO29141.1 - 0.43 8.0 3.1 0.44 8.0 2.1 1.0 1 0 0 1 1 1 0 Prominin Cauli_VI PF01693.11 EGO29144.1 - 3.7e-05 23.6 0.1 5.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Abhydrolase_6 PF12697.2 EGO29145.1 - 4.5e-19 69.2 0.3 5.8e-19 68.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO29145.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Asp PF00026.18 EGO29146.1 - 2.2e-28 99.4 6.4 2e-27 96.2 4.4 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO29146.1 - 2.6e-07 31.0 2.8 2.5e-05 24.7 0.6 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO29146.1 - 0.0009 19.0 0.3 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGO29146.1 - 0.0016 18.2 2.4 0.22 11.4 0.3 2.7 2 1 1 3 3 3 2 Retroviral aspartyl protease TAXi_C PF14541.1 EGO29146.1 - 0.0045 16.5 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGO29146.1 - 0.053 13.4 0.3 0.67 9.8 0.2 2.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal FlhC PF05280.6 EGO29147.1 - 0.0015 18.0 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) DUF2550 PF10739.4 EGO29154.1 - 0.087 12.7 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) DUF295 PF03478.13 EGO29156.1 - 0.11 11.8 0.1 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF295) TRAM_LAG1_CLN8 PF03798.11 EGO29161.1 - 4 6.9 7.4 17 4.9 5.2 1.8 1 1 0 1 1 1 0 TLC domain Peroxin-13_N PF04088.8 EGO29164.1 - 1.6e-42 145.1 0.0 2.7e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EGO29164.1 - 2.9e-10 39.4 0.0 4.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO29164.1 - 3.5e-10 39.1 1.0 0.00081 18.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EGO29164.1 - 2.5e-07 30.1 0.5 5.7e-07 29.0 0.4 1.6 1 1 0 1 1 1 1 Variant SH3 domain CHAT PF12770.2 EGO29165.1 - 2.1e-23 82.8 0.1 5.3e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EGO29165.1 - 1.1e-20 73.0 25.1 7.9e-06 25.4 0.1 10.6 5 4 5 11 11 11 8 TPR repeat TPR_12 PF13424.1 EGO29165.1 - 1.7e-16 59.8 27.9 0.011 15.5 0.3 11.8 5 4 7 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 EGO29165.1 - 0.0018 17.9 3.9 1.1e+02 2.9 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO29165.1 - 0.0036 16.8 21.0 7.5 6.3 0.0 11.0 13 0 0 13 13 13 1 Tetratricopeptide repeat Ank_5 PF13857.1 EGO29165.1 - 0.02 15.1 0.2 0.48 10.7 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_2 PF07719.12 EGO29165.1 - 0.25 11.3 14.8 51 4.1 0.0 8.6 10 0 0 10 10 10 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.14 EGO29170.1 - 1.2e-63 214.8 0.0 1.7e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 EGO29170.1 - 0.021 13.3 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EGO29170.1 - 0.023 13.4 0.0 0.039 12.6 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V Ribosomal_L16 PF00252.13 EGO29171.1 - 3.6e-34 117.3 0.4 4.3e-34 117.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.5 EGO29172.1 - 2.9e-66 223.0 4.6 5.7e-66 222.0 3.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGO29172.1 - 2.6e-33 114.4 0.3 1.1e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Snurportin1 PF11538.3 EGO29173.1 - 0.018 14.8 2.2 0.018 14.8 1.5 2.3 2 0 0 2 2 2 0 Snurportin1 U1snRNP70_N PF12220.3 EGO29173.1 - 2 8.7 7.8 0.95 9.8 0.9 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MFS_1 PF07690.11 EGO29174.1 - 2.7e-26 92.1 34.0 3.6e-26 91.7 23.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO29174.1 - 0.00054 18.2 5.3 0.00076 17.8 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L32p PF01783.18 EGO29175.1 - 1.6e-15 57.0 6.6 1.6e-15 57.0 3.8 1.6 1 1 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.1 EGO29175.1 - 0.0011 18.7 1.8 0.0025 17.5 1.3 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 DZR PF12773.2 EGO29175.1 - 0.028 14.2 0.5 0.046 13.5 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Stc1 PF12898.2 EGO29175.1 - 0.12 12.4 1.2 0.21 11.6 0.9 1.3 1 0 0 1 1 1 0 Stc1 domain GFA PF04828.9 EGO29175.1 - 0.16 11.9 1.0 1.5 8.8 0.7 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme MatE PF01554.13 EGO29178.1 - 3.2e-49 166.6 28.7 9.2e-29 100.1 5.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EGO29178.1 - 3.8e-07 30.0 8.7 3.8e-07 30.0 6.0 4.2 4 1 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Bac_surface_Ag PF01103.18 EGO29179.1 - 3.9e-46 158.0 0.3 4.7e-46 157.7 0.2 1.1 1 0 0 1 1 1 1 Surface antigen IBN_N PF03810.14 EGO29179.1 - 0.02 14.8 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain OMP_b-brl PF13505.1 EGO29179.1 - 0.09 12.7 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain Ribosomal_S8 PF00410.14 EGO29180.1 - 1.3e-15 57.4 0.0 2.3e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Transaldolase PF00923.14 EGO29181.1 - 7.7e-33 113.8 0.1 4.5e-32 111.3 0.0 1.9 1 1 0 1 1 1 1 Transaldolase SIN1 PF05422.7 EGO29182.1 - 1e-40 139.7 0.0 3.5e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EGO29182.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG AAA_12 PF13087.1 EGO29183.1 - 1.4e-31 109.4 0.1 1.6e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EGO29183.1 - 0.0011 18.5 0.0 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EGO29183.1 - 0.023 14.2 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.1 EGO29184.1 - 4.2e-42 143.8 0.0 4.9e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO29184.1 - 0.025 14.1 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGO29184.1 - 0.05 13.1 0.0 0.26 10.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.1 EGO29184.1 - 0.065 13.3 0.1 0.14 12.3 0.1 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 EGO29184.1 - 0.079 12.4 0.3 6.6 6.0 0.0 2.2 1 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Mg_trans_NIPA PF05653.9 EGO29185.1 - 1e-97 326.7 11.1 1.2e-97 326.5 7.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGO29185.1 - 4.9e-06 26.7 0.3 4.9e-06 26.7 0.2 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGO29185.1 - 0.012 15.6 3.8 0.012 15.6 2.6 2.6 2 0 0 2 2 2 0 EamA-like transporter family DUF4611 PF15387.1 EGO29185.1 - 0.18 11.9 1.3 0.32 11.1 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RseC_MucC PF04246.7 EGO29185.1 - 4.3 6.9 8.5 5 6.6 0.1 3.0 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Peptidase_M24 PF00557.19 EGO29186.1 - 9.5e-44 149.4 0.0 1.3e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGO29186.1 - 5.2e-25 88.4 0.0 1.8e-19 70.5 0.0 2.7 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF3243 PF11588.3 EGO29186.1 - 0.034 14.1 0.0 0.097 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) G-alpha PF00503.15 EGO29187.1 - 5e-138 460.0 0.0 6.3e-138 459.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO29187.1 - 1.2e-05 24.6 0.0 2.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AA_kinase PF00696.23 EGO29189.1 - 1.3e-35 123.1 0.0 2.1e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 EGO29189.1 - 3e-12 45.7 0.5 2.2e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EGO29189.1 - 7.6e-10 38.1 0.9 9.6e-08 31.4 0.1 2.8 3 0 0 3 3 3 2 ACT domain ChAPs PF09295.5 EGO29190.1 - 3e-148 493.8 0.0 1.2e-146 488.5 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EGO29190.1 - 1.1e-06 28.8 2.4 0.00017 21.8 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO29190.1 - 3.4e-06 26.5 2.0 1.3 9.0 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO29190.1 - 1e-05 25.5 1.2 2 8.5 0.0 3.9 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGO29190.1 - 3.7e-05 23.2 2.8 0.042 13.5 0.0 4.0 3 1 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 EGO29190.1 - 0.00026 20.5 4.5 0.39 10.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO29190.1 - 0.00061 20.2 5.0 20 6.1 0.0 6.2 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO29190.1 - 0.002 18.0 5.3 1.5 8.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGO29190.1 - 0.0066 15.5 3.6 0.78 8.7 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.3 EGO29190.1 - 0.0068 15.2 1.0 0.2 10.3 0.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EGO29190.1 - 0.0091 16.6 6.0 4.2 8.1 0.1 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO29190.1 - 0.49 10.0 4.7 38 4.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO29190.1 - 1.1 9.1 3.7 7 6.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.23 EGO29193.1 - 2.9e-99 332.3 0.0 4.4e-99 331.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGO29193.1 - 2.4e-67 227.0 0.0 4.9e-67 226.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EGO29193.1 - 2.6e-41 141.4 0.0 4.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EGO29193.1 - 8.3e-38 130.4 0.0 1.5e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO29193.1 - 3.3e-34 118.1 0.0 1.1e-33 116.3 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 EGO29193.1 - 2.3e-31 108.1 0.1 1.1e-30 105.8 0.1 2.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGO29193.1 - 1.4e-30 106.4 0.0 1.9e-29 102.7 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGO29193.1 - 8.9e-23 80.8 0.0 1.8e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EGO29193.1 - 1.5e-19 71.1 0.0 2.8e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EGO29193.1 - 1.4e-13 50.9 4.0 4.5e-07 30.0 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGO29193.1 - 1.9e-09 37.7 0.4 5.3e-08 33.0 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family AMP-binding_C PF13193.1 EGO29193.1 - 3.1e-09 37.6 0.1 9.1e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EGO29193.1 - 0.0011 18.0 0.8 0.03 13.2 0.0 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.21 EGO29193.1 - 0.0016 17.9 0.6 0.014 14.9 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 EGO29193.1 - 0.002 17.8 0.7 0.028 14.1 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family ACP_syn_III PF08545.5 EGO29193.1 - 0.01 15.4 0.3 0.028 14.0 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2235 PF09994.4 EGO29193.1 - 0.03 13.6 0.0 0.48 9.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.20 EGO29193.1 - 0.034 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) Transp_cyt_pur PF02133.10 EGO29194.1 - 2.4e-29 102.1 41.5 5.1e-29 101.0 28.8 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 EGO29195.1 - 7.2e-18 64.4 34.3 7.2e-18 64.4 23.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO29195.1 - 1.2e-11 44.3 8.5 1.2e-11 44.3 5.9 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2069 PF09842.4 EGO29195.1 - 5 7.1 10.4 0.56 10.1 0.7 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2069) UNC-93 PF05978.11 EGO29196.1 - 1.9e-15 56.7 7.5 1.9e-15 56.7 5.2 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGO29196.1 - 7.8e-14 51.1 33.9 1.3e-13 50.3 23.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_7 PF08395.7 EGO29196.1 - 0.0053 15.8 1.9 0.0053 15.8 1.3 2.5 4 0 0 4 4 4 1 7tm Chemosensory receptor UNC-93 PF05978.11 EGO29197.1 - 6.6e-14 51.6 6.3 6.6e-14 51.6 4.4 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGO29197.1 - 8.5e-12 44.4 34.4 8.5e-12 44.4 23.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO29198.1 - 6.5e-15 54.9 7.5 6.5e-15 54.9 5.2 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGO29198.1 - 1e-13 50.7 36.5 1.7e-13 50.0 25.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_7 PF08395.7 EGO29198.1 - 9.2 5.1 14.3 0.036 13.1 2.2 2.6 3 1 0 3 3 3 0 7tm Chemosensory receptor Ion_trans_2 PF07885.11 EGO29201.1 - 5.4e-29 99.7 34.0 1.6e-17 62.9 7.2 3.1 3 0 0 3 3 3 2 Ion channel Ank PF00023.25 EGO29202.1 - 7.1e-22 76.0 0.4 5.4e-10 38.5 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 EGO29202.1 - 5e-20 71.6 0.0 6.1e-12 45.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO29202.1 - 5.8e-20 71.2 1.5 3.7e-12 46.3 0.1 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO29202.1 - 7.2e-16 57.8 0.4 4.2e-08 33.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO29202.1 - 5.1e-10 38.5 0.2 0.0028 17.7 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Med9 PF07544.8 EGO29202.1 - 0.081 12.6 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 zf-RING_2 PF13639.1 EGO29205.1 - 1e-07 31.6 6.5 2.1e-07 30.6 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EGO29205.1 - 7.2e-06 25.8 3.9 1.5e-05 24.8 2.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EGO29205.1 - 8.4e-06 25.8 3.2 1.9e-05 24.7 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGO29205.1 - 0.0036 17.1 1.7 0.0077 16.0 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGO29205.1 - 0.035 14.1 6.2 0.075 13.0 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 EGO29205.1 - 0.083 12.5 7.6 0.15 11.7 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EGO29205.1 - 0.43 10.3 6.0 0.96 9.2 4.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_RING PF05883.6 EGO29205.1 - 0.47 10.2 1.6 0.86 9.4 0.4 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_2 PF13923.1 EGO29205.1 - 1.3 9.1 8.6 2.6 8.1 6.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGO29205.1 - 2 8.4 5.8 5 7.2 4.1 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 EGO29205.1 - 3.4 7.4 5.1 7.6 6.2 3.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EGO29206.1 - 9.4e-37 126.1 0.0 3e-36 124.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO29206.1 - 1.4e-17 63.3 0.2 1.1e-16 60.3 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO29206.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGO29206.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Pilin_PilX PF11530.3 EGO29206.1 - 0.11 12.1 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Minor type IV pilin, PilX CTP_synth_N PF06418.9 EGO29207.1 - 2.9e-117 390.6 0.1 3.8e-117 390.2 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGO29207.1 - 6e-49 166.1 0.0 9.7e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO29207.1 - 8.9e-05 22.0 0.0 0.00023 20.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EGO29207.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 EGO29208.1 - 5.2e-42 143.1 0.2 1.3e-15 57.7 0.0 4.9 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EGO29208.1 - 6.4e-38 130.1 0.0 1.6e-37 128.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO29208.1 - 1e-26 93.9 15.5 1.1e-22 80.7 0.0 6.0 6 0 0 6 6 5 2 AAA domain AAA_19 PF13245.1 EGO29208.1 - 1e-16 60.4 2.0 0.013 15.1 0.0 6.7 7 0 0 7 7 6 4 Part of AAA domain AAA_5 PF07728.9 EGO29208.1 - 2.9e-10 40.0 0.6 0.011 15.4 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGO29208.1 - 4.9e-10 40.2 13.7 0.027 15.2 0.0 6.0 6 0 0 6 6 4 3 AAA domain AAA_22 PF13401.1 EGO29208.1 - 6.3e-10 39.2 10.3 0.025 14.7 0.1 7.2 4 3 0 4 4 4 3 AAA domain Mg_chelatase PF01078.16 EGO29208.1 - 3.8e-09 36.0 0.0 0.3 10.2 0.0 4.4 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EGO29208.1 - 3.9e-09 36.3 0.0 1 8.8 0.0 5.2 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EGO29208.1 - 2.9e-07 30.8 3.3 2 8.7 0.0 5.0 4 0 0 4 4 4 3 AAA domain RuvB_N PF05496.7 EGO29208.1 - 4.3e-07 29.2 0.4 0.62 9.0 0.0 4.3 4 1 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO29208.1 - 8.6e-07 29.1 9.2 0.26 11.2 0.0 5.5 5 0 0 5 5 4 3 AAA ATPase domain IstB_IS21 PF01695.12 EGO29208.1 - 2.8e-06 26.8 3.2 1.1 8.6 0.0 4.2 5 0 0 5 5 3 3 IstB-like ATP binding protein RNA_helicase PF00910.17 EGO29208.1 - 3.3e-06 27.2 0.1 1.5 9.0 0.0 4.2 4 0 0 4 4 3 2 RNA helicase Torsin PF06309.6 EGO29208.1 - 0.0001 22.1 0.1 4.6 7.1 0.0 4.5 4 0 0 4 4 4 1 Torsin Sigma54_activat PF00158.21 EGO29208.1 - 0.00017 21.1 0.8 3 7.3 0.0 4.3 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_33 PF13671.1 EGO29208.1 - 0.00017 21.4 10.0 1.1 9.0 0.0 4.2 4 0 0 4 4 3 3 AAA domain AAA_24 PF13479.1 EGO29208.1 - 0.00018 21.1 10.9 0.98 8.9 0.0 4.9 4 1 0 4 4 4 2 AAA domain ResIII PF04851.10 EGO29208.1 - 0.00055 19.8 5.8 0.3 10.9 0.0 4.6 4 1 0 5 5 5 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EGO29208.1 - 0.00068 19.6 0.0 1.1 9.3 0.0 3.7 3 0 0 3 3 3 1 Sigma-54 interaction domain SRP54 PF00448.17 EGO29208.1 - 0.0073 15.7 2.7 0.37 10.1 0.0 3.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain VirE PF05272.6 EGO29208.1 - 0.0082 15.6 0.0 0.058 12.8 0.0 2.3 2 0 0 2 2 2 1 Virulence-associated protein E AAA_25 PF13481.1 EGO29208.1 - 0.014 14.8 0.2 33 3.7 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EGO29208.1 - 0.017 15.0 17.5 0.92 9.4 0.0 4.9 5 0 0 5 5 4 0 AAA domain NTPase_1 PF03266.10 EGO29208.1 - 0.064 12.9 2.1 32 4.1 0.0 3.6 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.22 EGO29208.1 - 0.63 10.3 7.7 22 5.3 0.0 4.6 5 0 0 5 5 4 0 ABC transporter WD40 PF00400.27 EGO29209.1 - 6.9e-32 108.1 18.3 6e-08 32.2 0.8 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Pheromone PF08015.6 EGO29209.1 - 3.4 8.5 8.3 11 6.9 0.9 3.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Cellulase PF00150.13 EGO29210.1 - 5.6e-46 156.9 0.9 9.2e-46 156.2 0.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TraW_N PF12477.3 EGO29210.1 - 3.2 7.7 6.0 21 5.1 0.1 3.1 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal Cellulase PF00150.13 EGO29211.1 - 2.3e-46 158.2 0.3 3e-46 157.8 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EGO29211.1 - 4.7e-13 48.5 5.0 2.1e-12 46.4 3.4 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Phytochelatin_C PF09328.5 EGO29211.1 - 1.5 8.2 3.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) WD40 PF00400.27 EGO29212.1 - 1.4e-73 240.3 31.8 1.4e-14 53.2 3.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGO29212.1 - 2.4e-08 33.3 0.1 3 7.4 0.0 5.7 6 0 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EGO29212.1 - 7.5e-07 28.2 3.3 0.67 8.6 1.8 4.9 2 2 2 4 4 4 3 Nup133 N terminal like TFIIIC_delta PF12657.2 EGO29212.1 - 0.0099 15.6 6.2 0.77 9.4 1.6 3.4 3 1 0 3 3 3 2 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EGO29212.1 - 2.7 5.6 4.3 3.4 5.3 0.3 2.5 1 1 0 2 2 2 0 IKI3 family Aminotran_1_2 PF00155.16 EGO29213.1 - 1.6e-58 198.4 0.0 1.8e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGO29213.1 - 0.0049 15.4 0.0 0.016 13.7 0.0 1.7 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase Bin3 PF06859.7 EGO29214.1 - 2.6e-33 114.2 0.0 3.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 EGO29214.1 - 2.1e-14 54.0 0.0 4.4e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO29214.1 - 3.3e-14 52.9 0.0 4.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO29214.1 - 2.7e-10 40.0 0.0 0.00075 19.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EGO29214.1 - 3.4e-10 40.2 0.0 0.0009 19.6 0.0 2.5 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EGO29214.1 - 3.7e-08 33.7 0.0 0.0011 19.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EGO29214.1 - 2.4e-06 27.5 0.0 5.4e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO29214.1 - 6.4e-06 25.3 0.0 0.0063 15.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.1 EGO29214.1 - 1.3e-05 25.4 0.0 0.0001 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO29214.1 - 0.015 14.6 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EGO29214.1 - 0.026 13.6 0.0 0.06 12.4 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGO29214.1 - 0.034 13.2 0.0 4.3 6.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 EGO29214.1 - 0.035 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 EGO29214.1 - 0.04 13.0 0.2 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EGO29214.1 - 0.049 12.3 0.0 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) zf-MYND PF01753.13 EGO29215.1 - 7.8e-10 38.4 15.0 1.5e-09 37.5 10.4 1.5 1 0 0 1 1 1 1 MYND finger Desulfoferrod_N PF06397.7 EGO29215.1 - 0.44 9.9 4.0 0.12 11.7 0.4 1.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain HEAT_EZ PF13513.1 EGO29215.1 - 0.63 10.6 3.1 1.8 9.1 0.3 2.5 2 0 0 2 2 2 0 HEAT-like repeat zf-MYND PF01753.13 EGO29216.1 - 5e-09 35.8 13.1 1.2e-08 34.6 9.1 1.7 1 0 0 1 1 1 1 MYND finger SAD_SRA PF02182.12 EGO29217.1 - 4.9e-30 103.8 0.0 4.1e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 SAD/SRA domain Ribosomal_L44 PF00935.14 EGO29217.1 - 0.25 11.3 3.1 0.28 11.2 0.8 2.0 2 0 0 2 2 2 0 Ribosomal protein L44 Glyco_hydro_18 PF00704.23 EGO29218.1 - 3.6e-58 197.6 4.8 4.5e-58 197.3 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGO29218.1 - 0.00072 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 JTB PF05439.7 EGO29221.1 - 0.0056 16.4 1.5 0.65 9.7 0.0 2.2 1 1 1 2 2 2 2 Jumping translocation breakpoint protein (JTB) SRP19 PF01922.12 EGO29222.1 - 2e-23 82.7 0.0 3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein COesterase PF00135.23 EGO29223.1 - 2.3e-60 204.8 0.0 6e-57 193.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO29223.1 - 0.022 14.3 0.2 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.5 EGO29223.1 - 0.049 12.5 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) MAPEG PF01124.13 EGO29224.1 - 4e-24 84.6 2.3 4.6e-24 84.4 1.6 1.0 1 0 0 1 1 1 1 MAPEG family SHMT PF00464.14 EGO29225.1 - 1.2e-167 557.2 0.0 1.5e-167 557.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EGO29225.1 - 0.0024 17.0 0.0 0.02 14.0 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Cu-oxidase PF00394.17 EGO29227.1 - 8.7e-36 123.2 1.7 1.9e-33 115.6 0.1 3.7 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO29227.1 - 7.1e-35 119.2 5.6 1.2e-31 108.8 0.4 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO29227.1 - 7.9e-34 116.1 0.4 7.9e-34 116.1 0.3 2.7 4 0 0 4 4 4 1 Multicopper oxidase FTR1 PF03239.9 EGO29228.1 - 3.2e-63 213.5 7.6 3.8e-63 213.2 5.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family zf-C2H2_6 PF13912.1 EGO29229.1 - 1.6e-27 94.4 98.3 2e-05 24.2 0.4 14.8 17 0 0 17 17 16 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO29229.1 - 7.8e-25 86.3 89.2 0.00063 19.8 0.3 15.8 16 0 0 16 16 16 9 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGO29229.1 - 1.6e-13 50.0 127.6 0.0024 18.1 0.2 16.9 18 0 0 18 18 16 10 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EGO29229.1 - 1.2e-08 34.4 42.1 0.012 15.2 0.0 12.4 14 0 0 14 14 14 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 EGO29229.1 - 1e-07 31.7 126.8 0.013 15.7 0.6 17.2 18 1 0 18 18 17 7 C2H2-type zinc finger zf-met PF12874.2 EGO29229.1 - 4.2e-07 29.9 99.5 0.0053 16.9 0.7 16.0 16 0 0 16 16 16 7 Zinc-finger of C2H2 type zf-RING_5 PF14634.1 EGO29229.1 - 1.2e-05 24.8 13.4 1.2e-05 24.8 9.3 8.2 7 3 1 8 8 6 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO29229.1 - 0.00051 19.6 12.2 0.00051 19.6 8.4 8.6 4 1 3 7 7 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO29229.1 - 0.0012 18.6 13.0 0.0012 18.6 9.0 7.9 6 3 2 8 8 6 1 Ring finger domain zf-C3HC4 PF00097.20 EGO29229.1 - 0.0012 18.4 13.7 0.0012 18.4 9.5 8.3 7 3 2 9 9 6 1 Zinc finger, C3HC4 type (RING finger) DUF629 PF04780.7 EGO29229.1 - 0.0016 17.0 7.1 0.0066 15.0 0.4 7.1 4 1 2 7 7 7 3 Protein of unknown function (DUF629) zf-C3HC4_2 PF13923.1 EGO29229.1 - 0.0022 18.0 14.0 0.0022 18.0 9.7 8.7 7 3 2 9 9 7 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EGO29229.1 - 0.0043 16.5 20.3 0.51 9.8 0.0 6.5 7 1 0 7 7 7 3 Rad50 zinc hook motif zf-RING_6 PF14835.1 EGO29229.1 - 0.018 14.8 8.3 0.14 11.9 5.8 2.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ribosomal_L34e PF01199.13 EGO29229.1 - 0.029 14.6 10.3 0.34 11.1 0.1 5.2 4 2 1 5 5 5 0 Ribosomal protein L34e zf-C2H2_2 PF12756.2 EGO29229.1 - 0.76 9.9 103.3 0.27 11.3 10.0 12.7 3 1 9 12 12 11 0 C2H2 type zinc-finger (2 copies) DUF434 PF04256.7 EGO29230.1 - 0.034 13.5 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF434) AAA_24 PF13479.1 EGO29230.1 - 0.075 12.6 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain zf-CCHC_3 PF13917.1 EGO29232.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO29232.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO29232.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVP_2 PF08284.6 EGO29233.1 - 4.5e-07 29.8 0.0 0.016 15.1 0.0 2.1 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO29233.1 - 2e-05 24.3 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO29233.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Siva PF05458.7 EGO29233.1 - 0.092 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Retrotrans_gag PF03732.12 EGO29234.1 - 1.2e-05 25.3 0.9 4.3e-05 23.5 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO29234.1 - 8.4e-05 22.3 2.0 0.00018 21.2 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Mad3_BUB1_I PF08311.7 EGO29234.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DUF4336 PF14234.1 EGO29236.1 - 1.5e-14 53.8 0.0 3.1e-09 36.4 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Hira PF07569.6 EGO29237.1 - 1.3e-43 148.7 0.1 3.5e-43 147.3 0.1 1.8 1 1 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EGO29237.1 - 4e-41 137.4 28.6 4.3e-09 35.8 0.1 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat SoxZ PF08770.6 EGO29237.1 - 0.069 12.5 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ MFS_1 PF07690.11 EGO29238.1 - 4.5e-13 48.6 13.4 4e-12 45.5 9.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 EGO29238.1 - 3.7 7.6 9.3 3 7.9 4.5 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) zf-RING_2 PF13639.1 EGO29239.1 - 2.2e-10 40.1 9.7 2.2e-10 40.1 6.7 2.8 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO29239.1 - 1.1e-09 37.8 6.9 1.1e-09 37.8 4.8 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO29239.1 - 6.1e-09 35.7 10.0 6.1e-09 35.7 6.9 3.2 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.3 EGO29239.1 - 6.2e-09 35.7 20.2 0.00031 20.7 0.3 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.1 EGO29239.1 - 1.7e-07 30.8 9.1 1.7e-07 30.8 6.3 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO29239.1 - 2e-07 30.5 8.7 2e-07 30.5 6.0 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO29239.1 - 4.4e-05 23.0 5.4 0.00045 19.8 3.7 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGO29239.1 - 6.2e-05 22.7 7.1 6.2e-05 22.7 4.9 3.7 3 2 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-met PF12874.2 EGO29239.1 - 9.5e-05 22.4 25.1 0.037 14.2 0.1 5.1 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-rbx1 PF12678.2 EGO29239.1 - 0.00033 20.7 7.3 0.00033 20.7 5.1 3.0 2 2 0 2 2 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGO29239.1 - 0.0018 17.9 3.2 0.006 16.3 2.2 1.9 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGO29239.1 - 0.0024 17.6 2.0 0.0024 17.6 1.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 EGO29239.1 - 0.0034 16.6 0.8 0.0034 16.6 0.6 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_4 PF14570.1 EGO29239.1 - 0.0061 16.1 5.6 0.0061 16.1 3.9 2.9 2 2 0 2 2 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EGO29239.1 - 0.016 14.6 3.9 0.038 13.5 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.1 EGO29239.1 - 0.043 14.1 19.4 3.4 8.1 1.2 5.4 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO29239.1 - 0.068 13.5 29.0 0.41 11.0 0.9 5.7 3 2 1 4 4 3 0 C2H2-type zinc finger zf-CHY PF05495.7 EGO29239.1 - 1.5 9.0 20.0 2.6 8.2 2.4 2.5 2 0 0 2 2 2 0 CHY zinc finger Nop14 PF04147.7 EGO29239.1 - 1.8 6.3 12.0 2.2 6.0 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family Ecl1 PF12855.2 EGO29239.1 - 2.2 7.6 13.4 3.3 7.0 0.0 3.6 3 1 0 3 3 3 0 Life-span regulatory factor Pkinase PF00069.20 EGO29240.1 - 3.7e-45 154.1 0.0 4.8e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29240.1 - 7.5e-40 136.6 0.0 9.3e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO29240.1 - 0.029 14.0 0.0 0.092 12.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGO29241.1 - 1.3e-41 142.4 0.0 3.4e-41 141.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29241.1 - 4.9e-38 130.6 0.0 9e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO29241.1 - 0.049 12.6 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EGO29241.1 - 0.084 12.5 0.3 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family STE3 PF02076.10 EGO29242.1 - 2.7e-72 243.2 16.2 3.3e-72 242.9 11.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Cerato-platanin PF07249.7 EGO29243.1 - 0.0022 17.9 0.9 0.074 13.0 0.1 2.3 1 1 1 2 2 2 2 Cerato-platanin GST_N_3 PF13417.1 EGO29245.1 - 0.0002 21.4 0.1 0.0066 16.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO29245.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO29245.1 - 0.017 15.1 0.2 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO29245.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Endonuc-EcoRV PF09233.6 EGO29246.1 - 0.058 12.7 0.0 0.06 12.6 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease EcoRV DEAD PF00270.24 EGO29247.1 - 6e-19 68.1 0.0 5.4e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO29247.1 - 5.3e-15 55.0 0.0 9.1e-13 47.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEM4 PF02602.10 EGO29247.1 - 0.0014 17.9 0.0 0.0059 15.8 0.0 1.9 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD ResIII PF04851.10 EGO29247.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.5 EGO29247.1 - 0.085 12.5 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 RQC domain SBP_bac_7 PF03480.8 EGO29247.1 - 0.14 11.2 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 CCDC14 PF15254.1 EGO29248.1 - 0.1 10.9 1.8 0.13 10.6 1.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 CPSF_A PF03178.10 EGO29249.1 - 2.1e-78 263.6 0.0 4.8e-78 262.4 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EGO29249.1 - 1.5e-10 39.9 0.0 3.8e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ATP_bind_1 PF03029.12 EGO29250.1 - 2.4e-72 243.3 0.0 2.9e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EGO29250.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO29250.1 - 0.89 10.3 5.4 0.35 11.6 1.2 2.4 2 1 0 2 2 2 0 AAA domain RNase_H PF00075.19 EGO29251.1 - 3.5e-09 37.0 0.0 2.9e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 RNase H zf-Mss51 PF13824.1 EGO29251.1 - 0.055 13.3 0.3 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TP_methylase PF00590.15 EGO29252.1 - 2.5e-16 60.0 0.0 3.4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Abhydrolase_3 PF07859.8 EGO29253.1 - 4.3e-13 49.3 0.1 1.4e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGO29253.1 - 1.4e-11 43.7 0.1 2.6e-11 42.9 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGO29253.1 - 1.2e-05 25.0 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EGO29253.1 - 0.00013 20.7 0.0 0.00018 20.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EGO29253.1 - 0.0016 18.3 0.3 0.0048 16.8 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family UDG PF03167.14 EGO29256.1 - 1.1e-15 57.4 0.0 2.5e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily PS_Dcarbxylase PF02666.10 EGO29258.1 - 3.7e-46 157.0 0.0 4.9e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PTS_EIIA_1 PF00358.15 EGO29258.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 S4_2 PF13275.1 EGO29258.1 - 0.071 12.7 0.1 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 S4 domain Asp PF00026.18 EGO29259.1 - 7.7e-81 271.7 4.7 9.8e-81 271.4 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGO29259.1 - 0.00019 21.0 0.1 0.00087 18.8 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGO29259.1 - 0.00042 20.3 0.5 0.0035 17.3 0.2 2.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO29259.1 - 0.036 14.5 0.6 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease Aldo_ket_red PF00248.16 EGO29260.1 - 9.2e-63 211.7 0.0 1.1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rad52_Rad22 PF04098.10 EGO29260.1 - 0.02 14.5 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Aldo_ket_red PF00248.16 EGO29261.1 - 8.4e-63 211.8 0.0 1e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.9 EGO29261.1 - 0.0093 15.6 0.1 2.9 7.6 0.1 2.4 2 0 0 2 2 2 2 NAF domain G-alpha PF00503.15 EGO29262.1 - 8e-122 406.6 0.0 9.5e-122 406.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO29262.1 - 1.3e-13 50.6 0.2 1.1e-09 37.7 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_22 PF13401.1 EGO29262.1 - 0.0034 17.5 0.1 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO29262.1 - 0.0081 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EGO29262.1 - 0.012 16.1 0.0 0.46 11.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EGO29262.1 - 0.033 13.6 0.0 8.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EGO29262.1 - 0.042 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGO29262.1 - 0.084 12.8 0.3 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain GPP34 PF05719.6 EGO29263.1 - 2.6e-62 210.5 0.2 3.3e-62 210.2 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PDCD2_C PF04194.8 EGO29264.1 - 0.15 11.6 0.4 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Chs3p PF12271.3 EGO29265.1 - 2.1e-51 174.6 11.6 5.8e-51 173.2 8.0 1.6 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Aldo_ket_red PF00248.16 EGO29266.1 - 2.6e-64 216.7 0.0 3.2e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.26 EGO29267.1 - 3.6e-06 26.9 0.1 7.2e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain Dimer_Tnp_hAT PF05699.9 EGO29267.1 - 0.062 12.9 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Skp1_POZ PF03931.10 EGO29267.1 - 0.091 12.8 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain zf-CCHC PF00098.18 EGO29270.1 - 1.9e-08 33.8 4.7 3.5e-08 32.9 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO29270.1 - 4.7e-05 23.3 0.1 4.7e-05 23.3 0.0 2.7 3 1 1 4 4 4 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO29270.1 - 0.011 15.4 1.7 0.025 14.3 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO29272.1 - 1.2e-06 28.4 0.7 2.3e-06 27.5 0.5 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO29272.1 - 7.5e-05 22.4 3.2 0.00013 21.7 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle YbaB_DNA_bd PF02575.11 EGO29273.1 - 0.043 13.7 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Lebercilin PF15619.1 EGO29273.1 - 0.062 12.7 0.7 0.075 12.4 0.5 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease NST1 PF13945.1 EGO29273.1 - 0.064 13.3 1.0 0.084 12.9 0.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Pkinase PF00069.20 EGO29274.1 - 1.2e-10 41.0 0.0 3.9e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29274.1 - 0.00085 18.4 0.1 0.0084 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase BTB PF00651.26 EGO29275.1 - 0.0099 15.8 0.1 0.01 15.8 0.1 1.0 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EGO29276.1 - 6.2e-05 22.9 0.1 0.00016 21.6 0.1 1.7 2 1 0 2 2 2 1 BTB/POZ domain DcpS_C PF11969.3 EGO29278.1 - 5.3e-23 81.4 0.0 8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EGO29278.1 - 3.7e-14 53.0 0.0 1.3e-11 44.8 0.0 2.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 EGO29278.1 - 0.1 13.1 0.7 1.4 9.4 0.1 2.2 2 0 0 2 2 2 0 HIT domain Alpha-L-AF_C PF06964.7 EGO29279.1 - 4.8e-40 137.1 1.9 7.2e-40 136.6 0.5 1.9 2 1 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus CBM_6 PF03422.10 EGO29279.1 - 0.044 13.9 4.7 0.062 13.4 2.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) D-ser_dehydrat PF14031.1 EGO29281.1 - 3.5e-19 68.7 0.2 2.9e-18 65.8 0.0 2.5 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EGO29281.1 - 3.9e-11 42.9 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PDGLE PF13190.1 EGO29281.1 - 0.041 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 PDGLE domain AAA_28 PF13521.1 EGO29282.1 - 9.8e-24 84.1 0.0 1.2e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO29282.1 - 4.3e-09 37.2 0.1 7.8e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO29282.1 - 4e-07 30.3 0.1 6.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO29282.1 - 0.00021 21.3 0.1 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGO29282.1 - 0.00025 20.9 0.1 0.00057 19.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGO29282.1 - 0.00031 20.9 0.1 0.00053 20.1 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EGO29282.1 - 0.0024 17.7 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EGO29282.1 - 0.0057 16.3 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGO29282.1 - 0.015 14.7 0.1 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EGO29282.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EGO29282.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGO29282.1 - 0.02 15.1 0.4 0.04 14.2 0.3 1.7 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EGO29282.1 - 0.021 13.7 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.13 EGO29282.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 EGO29282.1 - 0.029 14.5 0.2 0.16 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGO29282.1 - 0.032 12.9 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EGO29282.1 - 0.035 14.2 0.0 0.091 12.9 0.0 1.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EGO29282.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 EGO29282.1 - 0.067 13.0 0.0 0.16 11.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGO29282.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO29282.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase GTP_EFTU PF00009.22 EGO29282.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 EGO29282.1 - 0.11 11.9 0.1 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SMC_N PF02463.14 EGO29282.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Methyltransf_16 PF10294.4 EGO29283.1 - 1.3e-10 41.0 0.2 1e-05 25.0 0.0 2.4 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EGO29283.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGO29283.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MtrC PF04211.8 EGO29283.1 - 0.17 10.8 0.6 0.3 10.1 0.1 1.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C Fungal_lectin PF07938.7 EGO29284.1 - 3.3e-13 49.6 0.3 8.3e-13 48.2 0.2 1.6 1 1 0 1 1 1 1 Fungal fucose-specific lectin DUF2126 PF09899.4 EGO29284.1 - 0.14 10.1 0.0 5.6 4.8 0.0 2.0 1 1 1 2 2 2 0 Putative amidoligase enzyme (DUF2126) Metallophos_2 PF12850.2 EGO29285.1 - 3.9e-21 75.5 0.1 4.7e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGO29285.1 - 0.00013 21.4 2.4 0.21 10.9 0.3 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase UPF0203 PF05254.7 EGO29286.1 - 1.1e-18 66.7 2.0 6.6e-18 64.3 1.4 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EGO29286.1 - 0.0093 15.8 2.7 2 8.4 0.1 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein NDUFB10 PF10249.4 EGO29286.1 - 0.053 13.6 0.3 3.7 7.7 0.0 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Ribosomal_L33 PF00471.15 EGO29287.1 - 4.2e-09 36.5 0.0 5.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.3 EGO29287.1 - 0.028 13.8 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Ank_2 PF12796.2 EGO29288.1 - 0.00026 21.2 0.0 0.00056 20.1 0.0 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO29288.1 - 0.047 14.2 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 EGO29288.1 - 0.056 13.2 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 EGO29288.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Hist_deacetyl PF00850.14 EGO29289.1 - 2e-57 194.8 0.0 4.1e-57 193.8 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain TMEM51 PF15345.1 EGO29291.1 - 0.00074 19.2 0.3 0.0022 17.7 0.0 1.8 2 0 0 2 2 2 1 Transmembrane protein 51 PMP1_2 PF08114.6 EGO29291.1 - 0.049 13.1 0.4 0.086 12.3 0.2 1.3 1 0 0 1 1 1 0 ATPase proteolipid family DUF1180 PF06679.7 EGO29291.1 - 0.46 10.3 5.9 2.1 8.2 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) Gag_spuma PF03276.9 EGO29291.1 - 1.7 6.8 8.4 6 5.0 2.7 2.1 2 0 0 2 2 2 0 Spumavirus gag protein Alpha_adaptinC2 PF02883.15 EGO29293.1 - 0.0095 16.2 0.1 0.032 14.5 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain GLYCAM-1 PF05242.6 EGO29293.1 - 0.067 13.1 0.2 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Robl_LC7 PF03259.12 EGO29294.1 - 1e-07 31.4 0.0 3.2e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Roadblock/LC7 domain Gtr1_RagA PF04670.7 EGO29295.1 - 0.037 13.1 0.2 1.5 7.9 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region PDDEXK_1 PF12705.2 EGO29298.1 - 0.0071 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Ycf54 PF10674.4 EGO29298.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) DivIC PF04977.10 EGO29298.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator TarH PF02203.10 EGO29299.1 - 0.033 14.0 0.9 0.033 14.0 0.6 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue GRIP PF01465.15 EGO29300.1 - 1.4e-17 62.8 0.9 5.6e-17 60.9 0.3 2.3 2 0 0 2 2 2 1 GRIP domain DUF2968 PF11180.3 EGO29300.1 - 0.012 15.0 0.8 0.012 15.0 0.6 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF2968) Med12 PF09497.5 EGO29300.1 - 0.098 12.6 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Transcription mediator complex subunit Med12 Reo_sigmaC PF04582.7 EGO29300.1 - 1.7 7.7 20.9 1.2 8.2 6.7 2.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 EGO29300.1 - 9.3 5.6 56.8 2.9 7.2 32.7 4.0 1 1 1 2 2 2 0 Intermediate filament protein Kelch_4 PF13418.1 EGO29301.1 - 1.4e-26 91.9 13.6 3.2e-05 23.6 0.1 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGO29301.1 - 3.9e-26 90.5 7.4 6.3e-07 29.3 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF4110 PF13422.1 EGO29301.1 - 1.8e-22 79.0 0.0 6.1e-22 77.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.20 EGO29301.1 - 2.1e-19 68.7 1.3 2.8e-06 26.7 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EGO29301.1 - 1.7e-16 59.7 10.3 3e-05 23.8 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EGO29301.1 - 1.1e-15 56.9 9.0 0.00031 20.7 0.2 5.3 3 2 2 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EGO29301.1 - 5.6e-14 51.2 6.2 8.5e-05 22.1 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Nucleoplasmin PF03066.10 EGO29301.1 - 0.17 11.3 15.0 0.2 11.1 6.1 2.4 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 EGO29301.1 - 1.8 6.4 12.4 2.5 5.9 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EGO29301.1 - 4.1 7.7 21.1 6.2 7.2 7.1 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 EGO29301.1 - 5.8 4.6 7.2 10 3.8 5.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 EGO29301.1 - 9.7 5.3 13.0 4.8 6.3 5.9 2.1 2 0 0 2 2 2 0 NOA36 protein Asp PF00026.18 EGO29302.1 - 2.7e-58 197.7 1.1 3.7e-58 197.2 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO29302.1 - 2.7e-09 37.2 1.6 1.1e-08 35.2 1.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO29302.1 - 0.0067 16.8 0.5 0.085 13.3 0.2 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EGO29302.1 - 0.014 14.9 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal F-box-like PF12937.2 EGO29304.1 - 1.1e-08 34.6 0.8 3.8e-08 32.9 0.6 2.1 1 0 0 1 1 1 1 F-box-like Atg14 PF10186.4 EGO29305.1 - 1.7e-50 171.6 0.0 2.1e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 EzrA PF06160.7 EGO29305.1 - 0.071 11.2 0.4 0.09 10.9 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA STAT_alpha PF01017.15 EGO29305.1 - 0.11 12.2 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain APG6 PF04111.7 EGO29305.1 - 0.21 10.5 1.8 0.48 9.4 0.8 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 CAP_N PF01213.14 EGO29305.1 - 0.55 9.4 7.6 1.2 8.4 5.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ADH_N PF08240.7 EGO29306.1 - 3.6e-29 100.7 0.8 7.3e-29 99.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO29306.1 - 5.5e-11 42.1 0.1 1.6e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EGO29306.1 - 6.3e-06 25.7 0.3 1.6e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EGO29306.1 - 0.0035 15.8 0.2 0.012 14.1 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EGO29306.1 - 0.0048 16.4 0.1 0.0085 15.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EGO29306.1 - 0.11 11.5 0.2 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Ribosomal_L14e PF01929.12 EGO29308.1 - 5.4e-27 93.9 0.2 9.1e-27 93.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EGO29308.1 - 2.8e-06 26.7 1.1 3.5e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 KOW motif Rbsn PF11464.3 EGO29311.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Thionin PF00321.12 EGO29311.1 - 0.15 12.2 4.8 0.21 11.8 3.3 1.2 1 0 0 1 1 1 0 Plant thionin LRR_4 PF12799.2 EGO29313.1 - 0.003 17.1 2.4 0.63 9.7 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGO29313.1 - 0.043 13.5 0.1 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like ITAM_Cys-rich PF10538.4 EGO29314.1 - 0.077 12.5 0.4 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif F-box-like PF12937.2 EGO29315.1 - 0.012 15.2 0.8 0.023 14.3 0.1 1.8 2 0 0 2 2 2 0 F-box-like RNA_lig_T4_1 PF09511.5 EGO29316.1 - 9.8e-75 250.8 0.0 2.3e-74 249.6 0.0 1.6 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 EGO29316.1 - 5.8e-29 101.0 0.0 9.9e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EGO29316.1 - 2.6e-18 66.1 0.0 1.4e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 EGO29316.1 - 0.066 14.0 0.0 0.19 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO29316.1 - 0.073 12.8 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EGO29316.1 - 0.11 12.3 0.1 0.51 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain Exo70 PF03081.10 EGO29318.1 - 1.4e-34 119.5 0.0 2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CBFD_NFYB_HMF PF00808.18 EGO29319.1 - 1.4e-26 92.2 0.2 2.1e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO29319.1 - 1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EGO29319.1 - 0.0036 17.0 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PAN_3 PF08277.7 EGO29319.1 - 0.064 12.8 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 PAN-like domain WD40 PF00400.27 EGO29320.1 - 2.2e-05 24.1 0.6 0.007 16.2 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat MFS_1 PF07690.11 EGO29322.1 - 3.2e-40 137.9 46.0 3.2e-40 137.9 31.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DSPc PF00782.15 EGO29323.1 - 6e-46 155.3 0.0 3.2e-30 104.4 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO29323.1 - 0.00062 19.1 3.7 0.00076 18.8 0.8 2.1 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGO29323.1 - 0.023 14.7 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPn PF14671.1 EGO29323.1 - 0.1 12.5 0.7 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Dual specificity protein phosphatase, N-terminal half ANTAR PF03861.9 EGO29323.1 - 0.12 12.0 0.0 12 5.5 0.0 2.6 3 0 0 3 3 3 0 ANTAR domain SET PF00856.23 EGO29325.1 - 2e-13 50.9 0.1 5.1e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 SET domain MSP7_C PF12948.2 EGO29326.1 - 0.078 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain BIR PF00653.16 EGO29329.1 - 7.5e-31 106.3 2.2 9e-16 58.0 0.8 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.10 EGO29329.1 - 0.0033 17.1 0.2 0.72 9.6 0.0 2.9 3 0 0 3 3 3 2 BED zinc finger zf-C3HC PF07967.8 EGO29329.1 - 0.018 14.7 1.6 0.74 9.5 0.0 2.8 2 1 1 3 3 3 0 C3HC zinc finger-like Vesiculo_matrix PF06326.7 EGO29329.1 - 0.12 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Vesiculovirus matrix protein Lactamase_B_2 PF12706.2 EGO29330.1 - 2.1e-32 112.2 0.5 3.9e-32 111.3 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO29330.1 - 8.7e-11 41.8 0.2 2.5e-08 33.8 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EGO29330.1 - 1.6e-10 40.2 0.0 6e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease FA_desaturase PF00487.19 EGO29331.1 - 6.9e-25 87.9 13.8 6.9e-25 87.9 9.5 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGO29331.1 - 1.4e-08 34.8 0.1 2.5e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PTS-HPr PF00381.14 EGO29332.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 PTS HPr component phosphorylation site Kelch_6 PF13964.1 EGO29333.1 - 0.017 15.3 0.3 0.87 9.8 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 EGO29333.1 - 8.4 6.6 9.6 17 5.7 0.0 3.9 4 1 0 4 4 4 0 Galactose oxidase, central domain GMC_oxred_N PF00732.14 EGO29334.1 - 1.9e-52 178.3 0.0 2.5e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO29334.1 - 4.7e-23 82.0 0.2 3.8e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EGO29334.1 - 9.1e-09 34.6 0.1 4.9e-05 22.4 0.0 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO29334.1 - 2.5e-06 26.5 0.3 0.00015 20.7 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGO29334.1 - 3.5e-05 23.7 0.5 0.00011 22.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGO29334.1 - 0.00064 18.7 0.1 0.00094 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EGO29334.1 - 0.0013 17.2 0.1 0.0023 16.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGO29334.1 - 0.0063 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO29334.1 - 0.014 15.4 0.0 0.078 13.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO29334.1 - 0.12 11.4 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MutS_V PF00488.16 EGO29335.1 - 7.6e-98 326.6 0.0 1.2e-97 325.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO29335.1 - 3.5e-34 118.3 0.9 7.8e-34 117.2 0.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EGO29335.1 - 2e-17 63.1 0.6 5.7e-17 61.6 0.5 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EGO29335.1 - 6.2e-17 61.9 1.5 5.4e-16 58.8 0.0 3.1 4 0 0 4 4 4 1 MutS domain II Nol1_Nop2_Fmu PF01189.12 EGO29336.1 - 9.4e-34 117.0 0.0 7.4e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EGO29336.1 - 0.0042 17.0 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EGO29336.1 - 0.058 13.4 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EGO29337.1 - 5.3e-23 81.2 44.0 8.1e-23 80.6 30.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3767 PF12597.3 EGO29337.1 - 2.6 7.7 3.6 28 4.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) YL1 PF05764.8 EGO29338.1 - 2.4 7.7 7.3 3.8 7.0 5.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Pmp3 PF01679.12 EGO29339.1 - 2.1e-09 36.9 5.3 2.1e-09 36.9 3.7 1.5 2 0 0 2 2 2 1 Proteolipid membrane potential modulator ECF-ribofla_trS PF07155.7 EGO29339.1 - 0.12 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component G-alpha PF00503.15 EGO29340.1 - 1.2e-113 379.8 0.0 1.4e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO29340.1 - 1.4e-09 37.3 0.0 0.0002 20.6 0.0 3.0 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 EGO29340.1 - 0.0031 16.9 0.0 0.0086 15.5 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MCM PF00493.18 EGO29340.1 - 0.03 13.1 0.2 0.12 11.2 0.0 1.9 3 0 0 3 3 3 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 EGO29340.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.17 EGO29340.1 - 0.081 12.3 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 EGO29340.1 - 0.097 12.1 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AnfO_nitrog PF09582.5 EGO29341.1 - 0.043 12.9 0.1 0.093 11.8 0.0 1.5 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Na_trans_assoc PF06512.8 EGO29341.1 - 0.053 13.4 3.2 0.97 9.3 0.6 2.0 1 1 1 2 2 2 0 Sodium ion transport-associated La PF05383.12 EGO29342.1 - 4.7e-07 29.5 0.0 8.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 La domain Sporozoite_P67 PF05642.6 EGO29342.1 - 0.1 10.4 0.6 0.089 10.6 0.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4632 PF15451.1 EGO29342.1 - 2.6 8.0 5.2 6.9 6.6 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4632) Abhydrolase_3 PF07859.8 EGO29344.1 - 6.1e-64 215.4 0.0 7.3e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGO29344.1 - 2e-07 30.1 0.1 4.7e-07 28.8 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EGO29344.1 - 1.2e-06 27.4 0.0 1.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO29344.1 - 9.7e-06 25.3 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO29344.1 - 0.0002 20.6 0.0 0.0017 17.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGO29344.1 - 0.0021 17.9 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGO29344.1 - 0.0087 14.9 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AdoHcyase PF05221.12 EGO29346.1 - 2.9e-139 462.5 0.0 3.3e-139 462.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGO29346.1 - 3.9e-85 283.6 1.4 5.6e-85 283.1 0.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGO29346.1 - 3.7e-09 35.9 0.0 8.4e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGO29346.1 - 0.00021 20.7 0.1 0.00033 20.0 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGO29346.1 - 0.00068 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EGO29346.1 - 0.021 14.3 0.1 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 EGO29346.1 - 0.078 13.4 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mitochondr_Som1 PF11093.3 EGO29347.1 - 1.1e-06 28.2 0.5 1.6e-06 27.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Pox_A_type_inc PF04508.7 EGO29350.1 - 3.9 7.5 8.9 1.2 9.1 0.9 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat GST_N PF02798.15 EGO29351.1 - 4e-13 49.3 0.0 9.8e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGO29351.1 - 9.5e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO29351.1 - 8.2e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO29351.1 - 0.00049 20.0 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO29351.1 - 0.0048 17.3 0.0 0.0081 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO29351.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Laminin_II PF06009.7 EGO29352.1 - 1.3 8.7 8.2 0.49 10.1 1.6 2.2 2 0 0 2 2 2 0 Laminin Domain II IBR PF01485.16 EGO29353.1 - 1.3e-14 53.8 35.9 2e-08 33.9 4.5 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EGO29353.1 - 3e-05 23.9 4.9 3e-05 23.9 3.4 4.3 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO29353.1 - 7.1e-05 22.3 4.1 7.1e-05 22.3 2.8 4.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO29353.1 - 8.7e-05 22.3 4.6 8.7e-05 22.3 3.2 4.9 6 0 0 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGO29353.1 - 0.0045 16.6 5.3 0.0045 16.6 3.7 4.1 3 2 1 4 4 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO29353.1 - 0.0091 15.6 3.0 0.0091 15.6 2.1 2.6 3 0 0 3 3 3 1 RING-type zinc-finger RRM_5 PF13893.1 EGO29353.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EGO29353.1 - 0.017 14.9 4.9 0.017 14.9 3.4 4.7 2 1 2 4 4 2 0 Ring finger domain DUF2073 PF09846.4 EGO29353.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) RRM_1 PF00076.17 EGO29353.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_6 PF13912.1 EGO29353.1 - 0.071 13.0 0.2 0.071 13.0 0.2 3.9 3 1 1 4 4 4 0 C2H2-type zinc finger DUF2611 PF11022.3 EGO29355.1 - 4e-13 49.2 0.8 5.9e-13 48.7 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) DUF2034 PF10356.4 EGO29356.1 - 2.4e-27 95.3 0.3 1.1e-25 89.8 0.2 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EGO29356.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease RNA_pol_Rpb2_3 PF04565.11 EGO29358.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 3 GAS PF13851.1 EGO29360.1 - 0.00022 20.4 2.6 0.00027 20.1 1.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BicD PF09730.4 EGO29360.1 - 0.0003 19.3 5.8 0.0003 19.2 4.1 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Syntaxin-18_N PF10496.4 EGO29360.1 - 0.0015 18.3 2.0 0.0025 17.6 0.2 1.9 1 1 1 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Nup88 PF10168.4 EGO29360.1 - 0.0034 15.3 3.2 0.0037 15.1 2.2 1.1 1 0 0 1 1 1 1 Nuclear pore component Myosin_tail_1 PF01576.14 EGO29360.1 - 0.014 13.1 5.1 0.017 12.8 3.5 1.0 1 0 0 1 1 1 0 Myosin tail DUF1978 PF09321.5 EGO29360.1 - 0.015 14.7 2.2 0.016 14.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) APG6 PF04111.7 EGO29360.1 - 0.018 14.1 4.3 0.019 14.0 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3166 PF11365.3 EGO29360.1 - 0.036 14.5 1.3 0.04 14.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) TAF1_subA PF14929.1 EGO29360.1 - 0.037 12.4 0.5 0.044 12.2 0.3 1.0 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A DUF3584 PF12128.3 EGO29360.1 - 0.039 11.3 6.3 0.041 11.2 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4201 PF13870.1 EGO29360.1 - 0.06 12.7 3.1 0.076 12.4 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 EGO29360.1 - 0.062 13.1 4.6 0.18 11.6 3.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCPsignal PF00015.16 EGO29360.1 - 0.077 12.5 1.3 0.095 12.2 0.9 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2205 PF10224.4 EGO29360.1 - 0.081 12.5 2.4 0.18 11.4 0.2 2.4 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) BRE1 PF08647.6 EGO29360.1 - 0.15 12.0 1.6 0.29 11.1 0.9 1.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase IncA PF04156.9 EGO29360.1 - 0.22 11.0 7.5 0.28 10.7 5.2 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EGO29360.1 - 0.24 9.7 2.4 0.28 9.5 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 EGO29360.1 - 0.25 11.0 4.5 0.38 10.4 3.1 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FliD_N PF02465.13 EGO29360.1 - 0.29 11.5 3.1 3.2 8.1 2.1 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CALCOCO1 PF07888.6 EGO29360.1 - 0.3 9.3 6.2 0.98 7.6 4.1 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS-augmin3 PF14932.1 EGO29360.1 - 0.5 9.4 4.0 0.29 10.2 1.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 FUSC PF04632.7 EGO29360.1 - 0.68 8.3 2.8 0.68 8.2 1.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.7 EGO29360.1 - 0.7 10.0 7.8 0.91 9.7 0.4 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) CENP-Q PF13094.1 EGO29360.1 - 0.99 9.4 6.2 1.2 9.1 4.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cortex-I_coil PF09304.5 EGO29360.1 - 1.4 9.0 8.6 4.6 7.3 3.1 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil Atg14 PF10186.4 EGO29360.1 - 2.4 7.0 11.7 6.4 5.6 8.1 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAUS6_N PF14661.1 EGO29360.1 - 2.8 7.2 5.9 5.6 6.2 4.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fib_alpha PF08702.5 EGO29360.1 - 3.5 7.7 7.3 5.5 7.1 1.1 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EGO29360.1 - 5.9 6.4 7.3 13 5.3 0.0 2.5 2 1 2 4 4 3 0 Septum formation initiator SlyX PF04102.7 EGO29360.1 - 6.4 7.2 7.5 4.1 7.8 2.4 2.4 2 1 0 2 2 2 0 SlyX DUF1319 PF07028.6 EGO29360.1 - 7.6 6.7 7.8 1.2e+02 2.8 5.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Mito_carr PF00153.22 EGO29361.1 - 6.5e-60 198.8 2.5 5e-22 77.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRF PF01765.14 EGO29362.1 - 3.3e-30 104.7 4.1 6.5e-30 103.7 2.8 1.5 1 0 0 1 1 1 1 Ribosome recycling factor MalF_P2 PF14785.1 EGO29362.1 - 0.88 9.4 3.5 3.8 7.3 0.5 2.5 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain SNF2_N PF00176.18 EGO29363.1 - 3.7e-63 213.0 2.3 3.7e-63 213.0 1.6 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO29363.1 - 4.6e-11 42.4 0.1 4.8e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGO29363.1 - 7.8e-10 38.2 5.1 1.5e-09 37.3 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO29363.1 - 1e-08 35.0 6.6 2.6e-08 33.7 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO29363.1 - 1.5e-08 34.3 6.5 3e-08 33.3 4.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO29363.1 - 1.7e-08 34.0 7.0 3.9e-08 32.8 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO29363.1 - 5.9e-07 29.0 2.3 1.8e-06 27.5 1.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGO29363.1 - 3e-06 26.8 5.3 6e-06 25.8 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO29363.1 - 1.9e-05 24.4 6.9 5e-05 23.0 4.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RFX1_trans_act PF04589.8 EGO29363.1 - 0.014 15.1 0.9 0.028 14.1 0.6 1.4 1 0 0 1 1 1 0 RFX1 transcription activation region zf-RING_4 PF14570.1 EGO29363.1 - 0.16 11.5 6.0 0.44 10.1 4.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 EGO29363.1 - 0.19 11.6 4.3 12 5.7 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Prok-RING_4 PF14447.1 EGO29363.1 - 3.5 7.2 9.2 0.46 10.0 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ABC_membrane_2 PF06472.10 EGO29364.1 - 6.9e-81 271.4 0.2 1.2e-80 270.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGO29364.1 - 3.1e-15 56.6 0.0 5.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGO29364.1 - 0.0098 15.1 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGO29364.1 - 0.03 14.3 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGO29364.1 - 0.063 13.4 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.1 EGO29364.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EGO29364.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NOA36 PF06524.7 EGO29365.1 - 4.3 6.5 8.0 4.9 6.3 5.5 1.0 1 0 0 1 1 1 0 NOA36 protein Peptidase_M20 PF01546.23 EGO29366.1 - 1.2e-21 77.1 0.0 1.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO29366.1 - 1e-09 38.1 0.1 2.2e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGO29366.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 LRR_4 PF12799.2 EGO29367.1 - 7e-12 44.6 2.3 0.0084 15.7 0.0 6.5 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO29367.1 - 5.9e-09 35.5 2.3 0.069 12.9 0.0 5.1 5 1 1 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 EGO29367.1 - 7.6e-09 34.7 0.3 0.87 9.8 0.0 7.6 7 0 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EGO29367.1 - 0.065 13.4 5.4 1.6e+02 3.2 0.0 6.7 7 1 1 8 8 8 0 Leucine rich repeat STE3 PF02076.10 EGO29368.1 - 5.4e-71 238.9 15.8 6.4e-71 238.7 11.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_M20 PF01546.23 EGO29371.1 - 7.5e-19 67.9 0.0 1.1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO29371.1 - 4.6e-09 36.0 0.0 1e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain zf-ISL3 PF14690.1 EGO29375.1 - 0.018 15.0 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2415 PF10313.4 EGO29376.1 - 0.1 12.3 0.1 2 8.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) RicinB_lectin_2 PF14200.1 EGO29378.1 - 3.3e-21 75.6 2.7 2.1e-17 63.4 0.3 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EGO29378.1 - 0.0019 18.2 0.8 0.015 15.3 0.2 2.4 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain MASE2 PF05230.6 EGO29379.1 - 0.032 14.1 0.2 0.41 10.6 0.0 2.0 1 1 1 2 2 2 0 MASE2 domain Ank PF00023.25 EGO29380.1 - 7.4e-07 28.6 0.1 0.05 13.4 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGO29380.1 - 1.2e-06 28.6 0.1 2.6e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO29380.1 - 8.5e-05 22.4 0.2 0.57 10.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO29380.1 - 0.0014 19.0 0.1 0.43 11.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO29380.1 - 0.01 16.0 0.5 1.1 9.5 0.1 2.5 1 1 2 3 3 3 0 Ankyrin repeats (many copies) G-alpha PF00503.15 EGO29383.1 - 4.4e-136 453.6 0.0 4.9e-136 453.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO29383.1 - 2e-10 40.1 0.0 1.9e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EGO29383.1 - 0.0059 16.1 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EGO29383.1 - 0.058 13.8 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EGO29383.1 - 0.067 13.3 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain FA_desaturase PF00487.19 EGO29385.1 - 3.6e-15 56.1 21.9 6.2e-15 55.3 15.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGO29385.1 - 1.4e-11 44.0 0.0 3.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2805 PF10985.3 EGO29386.1 - 0.041 13.8 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) MOR2-PAG1_N PF14222.1 EGO29387.1 - 1.8e-139 466.0 0.0 3.3e-138 461.7 0.0 2.4 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EGO29387.1 - 5.4e-74 249.2 1.7 1.8e-73 247.5 1.2 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EGO29387.1 - 1e-19 69.7 1.1 1.3e-10 39.5 0.1 3.2 3 0 0 3 3 3 3 Cell morphogenesis central region DNA_mis_repair PF01119.14 EGO29388.1 - 2.2e-28 98.1 0.1 4.3e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGO29388.1 - 7e-14 51.6 0.0 1.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGO29388.1 - 6.8e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBS PF00571.23 EGO29389.1 - 1.5e-06 27.8 0.0 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 2 CBS domain PC_rep PF01851.17 EGO29392.1 - 1.5e-21 75.2 19.3 0.00031 20.8 0.1 9.0 9 0 0 9 9 9 6 Proteasome/cyclosome repeat Ank PF00023.25 EGO29392.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat TPR_5 PF12688.2 EGO29392.1 - 0.15 12.0 1.8 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat Cyclin_N PF00134.18 EGO29393.1 - 8.9e-46 154.5 2.1 2.7e-45 153.0 0.6 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO29393.1 - 1.7e-26 92.4 0.1 1.3e-25 89.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain NACHT PF05729.7 EGO29394.1 - 6.6e-05 22.6 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO29394.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO29394.1 - 0.00027 21.0 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO29394.1 - 0.0021 17.1 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO29394.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ELYS PF13934.1 EGO29394.1 - 0.051 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex assembly AAA_19 PF13245.1 EGO29394.1 - 0.056 13.2 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EGO29394.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EGO29394.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1803 PF08820.5 EGO29394.1 - 0.12 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Peptidase_S10 PF00450.17 EGO29397.1 - 5.2e-116 388.2 0.0 7e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGO29397.1 - 0.00027 20.9 0.0 0.0043 16.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyoxalase_2 PF12681.2 EGO29398.1 - 8.3e-11 42.4 0.0 1.1e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGO29398.1 - 0.00026 20.9 0.1 0.0063 16.4 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sigma70_r1_1 PF03979.9 EGO29398.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DAO PF01266.19 EGO29399.1 - 2.3e-19 69.5 1.3 4.1e-19 68.7 0.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO29399.1 - 0.0015 17.4 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO29399.1 - 0.0019 18.0 0.1 0.0034 17.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGO29399.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EGO29399.1 - 0.018 15.0 1.6 0.096 12.7 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO29399.1 - 0.018 14.1 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EGO29399.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FA_desaturase PF00487.19 EGO29402.1 - 4.7e-28 98.3 15.2 4.7e-28 98.3 10.5 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 EGO29402.1 - 8.8e-18 63.2 0.5 1.4e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Acetyltransf_3 PF13302.1 EGO29403.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO29403.1 - 0.00018 21.4 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGO29403.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO29403.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein HEAT_2 PF13646.1 EGO29405.1 - 5.6e-05 23.3 9.5 0.032 14.5 0.0 5.6 4 3 3 7 7 7 3 HEAT repeats HEAT PF02985.17 EGO29405.1 - 0.0046 16.9 3.1 12 6.3 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat FANCI_S2 PF14676.1 EGO29405.1 - 1.2 8.9 7.1 3 7.7 0.6 3.1 2 0 0 2 2 2 0 FANCI solenoid 2 NARP1 PF12569.3 EGO29406.1 - 4.2e-170 566.9 1.0 2.8e-168 560.8 0.4 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EGO29406.1 - 1.2e-14 53.6 13.4 0.0027 17.3 0.5 7.3 6 1 0 7 7 6 4 TPR repeat TPR_2 PF07719.12 EGO29406.1 - 1.2e-14 52.9 8.0 0.0083 15.9 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO29406.1 - 2.1e-13 50.5 10.8 0.25 12.0 0.1 8.3 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO29406.1 - 2.1e-11 43.9 14.9 0.036 14.4 0.0 7.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO29406.1 - 1.8e-10 40.5 3.4 4.5 8.1 0.0 9.0 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO29406.1 - 2.8e-07 30.3 10.7 0.47 10.4 0.1 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO29406.1 - 1.9e-05 24.0 7.9 0.0048 16.4 0.2 6.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO29406.1 - 2.2e-05 24.3 0.0 0.27 11.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO29406.1 - 0.00015 21.2 2.3 0.45 10.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO29406.1 - 0.0002 20.8 0.1 1.6 8.6 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO29406.1 - 0.011 15.5 0.6 13 5.7 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO29406.1 - 0.042 14.3 4.7 84 3.9 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO29406.1 - 0.087 13.2 1.7 1e+02 3.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EGO29406.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain FYTT PF07078.6 EGO29407.1 - 0.13 11.5 0.2 0.18 11.0 0.1 1.1 1 0 0 1 1 1 0 Forty-two-three protein Rnk_N PF14760.1 EGO29407.1 - 0.29 11.2 1.5 0.69 10.0 1.0 1.6 1 1 0 1 1 1 0 Rnk N-terminus Cwf_Cwc_15 PF04889.7 EGO29408.1 - 0.014 15.1 0.9 0.02 14.5 0.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Bd3614_N PF14442.1 EGO29408.1 - 0.51 10.3 6.2 0.087 12.8 1.7 1.7 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Hydrophobin PF01185.13 EGO29409.1 - 3.5e-14 53.0 13.0 4.4e-14 52.6 9.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin YjbE PF11106.3 EGO29409.1 - 0.3 11.0 7.1 0.45 10.5 4.9 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Toxin_12 PF07740.7 EGO29409.1 - 8.7 6.9 8.9 9.3 6.8 0.9 2.7 3 0 0 3 3 3 0 Ion channel inhibitory toxin Stn1 PF10451.4 EGO29410.1 - 3.1e-07 29.5 0.1 1.3e-05 24.1 0.0 2.4 3 0 0 3 3 3 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EGO29410.1 - 0.013 15.3 0.6 0.13 12.1 0.4 2.3 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain HMG-CoA_red PF00368.13 EGO29411.1 - 5.1e-161 535.4 5.0 6.8e-161 535.0 3.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EGO29411.1 - 1.2e-18 66.9 0.4 3e-18 65.7 0.3 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGO29411.1 - 1.8e-08 32.8 0.0 2.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Patched family Herpes_LMP1 PF05297.6 EGO29411.1 - 1.1 8.1 4.9 1.7 7.4 3.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) 3Beta_HSD PF01073.14 EGO29414.1 - 8.9e-29 100.0 0.0 2.8e-27 95.1 0.0 2.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO29414.1 - 6.5e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO29414.1 - 1.4e-11 43.8 0.0 5.4e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EGO29414.1 - 0.00011 22.2 0.0 0.00045 20.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGO29414.1 - 0.00012 21.0 0.1 0.0016 17.4 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EGO29414.1 - 0.00034 20.5 0.1 0.00095 19.1 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO29414.1 - 0.00096 18.8 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.16 EGO29415.1 - 2.1e-47 161.2 0.0 2.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EspF PF04806.7 EGO29415.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 EspF protein repeat ADH_N PF08240.7 EGO29416.1 - 1.1e-28 99.1 1.6 2.9e-28 97.7 1.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO29416.1 - 2.2e-13 49.8 0.0 4.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO29416.1 - 7.7e-05 23.5 0.0 0.00017 22.4 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EGO29416.1 - 0.00019 20.5 0.6 0.00027 20.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EGO29416.1 - 0.0066 16.5 0.3 0.014 15.4 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO29416.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2338 PF10100.4 EGO29416.1 - 0.02 13.2 0.0 0.027 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) NAD_binding_8 PF13450.1 EGO29416.1 - 0.025 14.6 0.3 0.062 13.3 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO29416.1 - 0.075 13.4 0.3 0.53 10.7 0.2 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO29416.1 - 0.12 10.7 1.1 0.17 10.3 0.8 1.1 1 0 0 1 1 1 0 HI0933-like protein NUDIX PF00293.23 EGO29417.1 - 8.2e-08 31.9 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AMP_N PF05195.11 EGO29417.1 - 0.0079 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Radical_SAM PF04055.16 EGO29419.1 - 1.5e-09 38.2 0.0 1.7e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGO29419.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.5 2 0 0 2 2 2 1 4Fe-4S single cluster domain Alba PF01918.16 EGO29419.1 - 0.016 14.7 0.2 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Alba Fer4_14 PF13394.1 EGO29419.1 - 0.054 13.5 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain AMP-binding PF00501.23 EGO29420.1 - 8.3e-71 238.5 0.0 1.2e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO29420.1 - 8e-67 224.7 0.0 2.1e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EGO29420.1 - 2.2e-14 53.4 0.0 8.2e-14 51.6 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGO29420.1 - 3.1e-09 36.6 0.0 6.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EGO29420.1 - 7.1e-09 36.4 0.0 2.1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EGO29420.1 - 0.00053 18.7 0.0 0.002 16.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO29420.1 - 0.036 14.0 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 NADH(P)-binding Condensation PF00668.15 EGO29420.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Condensation domain NmrA PF05368.8 EGO29420.1 - 0.29 10.3 0.0 0.5 9.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EGO29420.1 - 0.46 10.3 2.9 0.84 9.5 0.5 2.5 2 1 0 2 2 2 0 short chain dehydrogenase DDE_3 PF13358.1 EGO29421.1 - 3.9e-08 33.1 0.1 3e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF1546 PF07571.8 EGO29424.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Mito_carr PF00153.22 EGO29427.1 - 2.2e-59 197.1 0.1 8.7e-22 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.7 EGO29428.1 - 1.9e-32 111.2 2.7 3.5e-32 110.4 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO29428.1 - 2.4e-15 56.2 0.0 4.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO29428.1 - 8e-05 23.5 0.0 0.00016 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EGO29428.1 - 0.00073 18.6 0.9 0.001 18.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain DUF2338 PF10100.4 EGO29428.1 - 0.018 13.3 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Shikimate_DH PF01488.15 EGO29428.1 - 0.032 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO29428.1 - 0.035 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding His_Phos_2 PF00328.17 EGO29429.1 - 2.2e-29 102.8 0.0 5.5e-29 101.5 0.0 1.6 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) AMP-binding PF00501.23 EGO29430.1 - 8e-86 288.0 0.0 1e-85 287.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO29430.1 - 1.3e-14 54.8 0.1 3.1e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 EGO29430.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cyt-b5 PF00173.23 EGO29431.1 - 4.6e-22 77.6 0.0 8.9e-22 76.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EGO29431.1 - 8.8e-08 32.5 21.4 8.8e-08 32.5 14.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sec5 PF15469.1 EGO29432.1 - 6.2e-47 159.6 0.1 5.7e-46 156.5 0.0 2.7 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGO29432.1 - 0.041 13.7 0.3 0.19 11.5 0.0 2.3 3 0 0 3 3 3 0 Vps51/Vps67 DUF155 PF02582.9 EGO29433.1 - 1.6e-57 194.2 0.7 2e-57 193.8 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Gti1_Pac2 PF09729.4 EGO29435.1 - 1.3e-26 93.4 0.0 6.8e-23 81.3 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family DUF3395 PF11875.3 EGO29436.1 - 2.2e-30 105.2 0.2 1.6e-29 102.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) HhH-GPD PF00730.20 EGO29436.1 - 3.8e-17 62.5 0.0 1.6e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DnaJ PF00226.26 EGO29436.1 - 6.5e-13 48.2 0.2 1.6e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain NUDIX_4 PF14815.1 EGO29436.1 - 1.3e-07 31.0 0.0 1.3e-06 27.8 0.0 2.4 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.18 EGO29436.1 - 0.023 14.4 0.2 0.071 12.8 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif SURF4 PF02077.10 EGO29437.1 - 8.7e-93 310.5 10.9 9.9e-93 310.3 7.5 1.0 1 0 0 1 1 1 1 SURF4 family Sugar_tr PF00083.19 EGO29438.1 - 6.2e-109 364.5 22.0 8.2e-109 364.1 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO29438.1 - 2.7e-21 75.6 37.2 8.4e-15 54.3 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO29438.1 - 8.3e-06 24.2 6.3 1.6e-05 23.3 2.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) ProRS-C_1 PF09180.6 EGO29439.1 - 3.5e-22 78.0 2.3 6.1e-22 77.3 0.4 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EGO29439.1 - 6.1e-21 74.7 0.1 9.9e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO29439.1 - 1.6e-15 56.7 0.0 4.5e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 EGO29439.1 - 5.3e-11 42.4 0.1 9.9e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_1 PF00133.17 EGO29440.1 - 9.4e-159 529.1 0.0 1.2e-158 528.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGO29440.1 - 3.7e-26 91.6 1.9 4.2e-26 91.5 0.3 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGO29440.1 - 2.6e-23 82.3 2.3 1.2e-15 57.0 0.3 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EGO29440.1 - 4e-06 26.3 3.3 8.8e-06 25.2 2.3 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EGO29440.1 - 5.8e-05 22.3 0.0 0.13 11.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EGO29440.1 - 0.00036 19.4 0.0 0.0057 15.5 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (R) Neuropep_like PF15161.1 EGO29440.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide-like DJ-1_PfpI PF01965.19 EGO29441.1 - 3.4e-26 91.4 0.0 4.5e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGO29441.1 - 5.9e-12 45.1 0.0 7.1e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EGO29441.1 - 0.0088 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S64 PF08192.6 EGO29442.1 - 0.041 12.2 1.6 0.042 12.2 1.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1183 PF06682.7 EGO29443.1 - 4.6 6.7 5.7 4.9 6.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) CorA PF01544.13 EGO29444.1 - 4.6e-09 35.7 2.3 7.6e-09 35.0 1.6 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.24 EGO29445.1 - 9.9e-44 148.7 0.0 2e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGO29445.1 - 3.9e-08 33.3 0.0 9.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGO29445.1 - 8.2e-07 28.8 0.0 4.4e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO29445.1 - 3.6e-06 27.0 0.4 1.2e-05 25.3 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO29445.1 - 5.8e-06 26.4 0.2 0.00032 20.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGO29445.1 - 4.2e-05 23.2 0.0 0.00016 21.3 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGO29445.1 - 6.3e-05 23.7 0.0 0.00018 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO29445.1 - 8.2e-05 21.7 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGO29445.1 - 0.00034 20.0 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGO29445.1 - 0.00092 18.0 0.0 0.0016 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGO29445.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO29445.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO29445.1 - 0.0022 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EGO29445.1 - 0.0039 17.1 0.4 0.0072 16.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EGO29445.1 - 0.0039 16.7 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.4 EGO29445.1 - 0.0047 16.8 0.2 0.0098 15.8 0.2 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) PhoH PF02562.11 EGO29445.1 - 0.0052 16.0 0.0 0.065 12.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EGO29445.1 - 0.0066 15.6 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGO29445.1 - 0.0072 16.6 0.1 0.031 14.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain KaiC PF06745.8 EGO29445.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EGO29445.1 - 0.017 14.6 0.1 0.088 12.2 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGO29445.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGO29445.1 - 0.023 13.6 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGO29445.1 - 0.028 13.8 0.1 0.092 12.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGO29445.1 - 0.035 14.2 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EGO29445.1 - 0.036 13.7 0.0 0.58 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 EGO29445.1 - 0.042 13.8 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EGO29445.1 - 0.051 13.1 0.0 0.18 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EGO29445.1 - 0.053 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EGO29445.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EGO29445.1 - 0.13 11.7 0.3 14 5.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MR_MLE_C PF13378.1 EGO29446.1 - 9.9e-17 60.9 0.1 2.3e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGO29446.1 - 5.5e-15 55.6 0.6 6e-13 49.1 0.0 2.9 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGO29446.1 - 2.6e-08 33.8 0.0 6.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TctB PF07331.6 EGO29448.1 - 0.00089 18.9 1.2 0.00089 18.9 0.8 2.4 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family HET PF06985.6 EGO29449.1 - 1.1e-22 80.7 0.4 2.1e-22 79.7 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NdhN PF11909.3 EGO29449.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N PIGA PF08288.7 EGO29450.1 - 7.5e-36 122.3 1.0 1.5e-35 121.4 0.2 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGO29450.1 - 1.1e-23 83.4 0.0 2.4e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO29450.1 - 7.4e-14 52.0 0.1 7.9e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGO29450.1 - 1.9e-13 50.5 0.5 3.5e-13 49.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGO29450.1 - 1.2e-12 48.2 0.1 2.1e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGO29450.1 - 0.00053 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EGO29450.1 - 0.0023 17.7 0.5 0.0056 16.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like UNC-50 PF05216.8 EGO29452.1 - 2.2e-85 285.5 11.6 2.5e-85 285.3 8.1 1.0 1 0 0 1 1 1 1 UNC-50 family FixP_N PF14715.1 EGO29452.1 - 3.6 7.0 7.5 6.8 6.1 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Metallophos PF00149.23 EGO29453.1 - 4.4e-43 147.0 0.9 6.5e-43 146.4 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S1-P1_nuclease PF02265.11 EGO29454.1 - 9.6e-46 156.4 0.0 7.3e-44 150.2 0.0 2.4 1 1 0 1 1 1 1 S1/P1 Nuclease Methyltransf_16 PF10294.4 EGO29455.1 - 3.5e-05 23.3 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EGO29455.1 - 0.0008 19.1 0.0 0.0025 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO29455.1 - 0.0022 18.3 0.0 0.014 15.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO29455.1 - 0.0066 16.0 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Oxysterol_BP PF01237.13 EGO29456.1 - 4.4e-49 166.8 0.1 1.3e-35 122.5 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein DUF2531 PF10748.4 EGO29456.1 - 0.027 13.6 0.1 0.069 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) Sin3_corepress PF08295.7 EGO29457.1 - 3.6e-35 119.7 0.1 1.4e-34 117.8 0.1 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 EGO29457.1 - 6.4e-31 105.7 0.4 1.4e-14 53.3 0.0 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat bZIP_1 PF00170.16 EGO29458.1 - 1.5e-07 31.2 3.7 3.4e-07 30.1 2.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO29458.1 - 9.7e-07 28.5 4.7 7.1e-06 25.7 0.9 2.3 1 1 1 2 2 2 2 Basic region leucine zipper IF4E PF01652.13 EGO29460.1 - 7.4e-49 165.4 0.1 1.1e-48 164.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E zf-CCHC PF00098.18 EGO29463.1 - 4.7e-07 29.4 1.3 9.4e-07 28.4 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO29463.1 - 1.5e-05 24.9 0.4 4.3e-05 23.5 0.3 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EGO29463.1 - 0.15 11.7 1.3 0.33 10.6 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle UBN2_2 PF14227.1 EGO29464.1 - 6.7e-10 38.5 0.7 9e-10 38.1 0.5 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO29464.1 - 1.2e-06 28.3 0.3 1.5e-06 28.0 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PAP2 PF01569.16 EGO29467.1 - 1.7e-16 60.0 12.5 1.7e-16 60.0 8.7 2.7 2 1 1 3 3 3 1 PAP2 superfamily Alpha_kinase PF02816.13 EGO29472.1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family DUF3668 PF12416.3 EGO29472.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Cep120 protein zf-CCHC_6 PF15288.1 EGO29474.1 - 0.0069 16.0 2.4 0.015 14.9 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle FrhB_FdhB_C PF04432.8 EGO29474.1 - 0.07 12.5 0.6 0.15 11.4 0.4 1.4 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus UBN2_3 PF14244.1 EGO29479.1 - 1.3e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO29479.1 - 3.2e-06 26.6 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO29479.1 - 1.4e-05 24.3 0.1 2.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EGO29479.1 - 0.00016 21.4 0.1 0.00028 20.6 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-PARP PF00645.13 EGO29479.1 - 0.047 13.9 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CENP-H PF05837.7 EGO29480.1 - 0.012 15.7 1.7 0.026 14.6 1.2 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spo0A_C PF08769.6 EGO29480.1 - 0.095 12.5 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF3713 PF12506.3 EGO29480.1 - 0.25 11.4 1.9 3.2 7.8 1.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) tRNA-synt_2 PF00152.15 EGO29481.1 - 5.2e-72 242.4 0.0 6.3e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO29481.1 - 2.8e-09 36.7 0.2 7.5e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EGO29481.1 - 0.063 12.8 0.0 0.58 9.7 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EGO29481.1 - 0.11 11.7 0.1 2 7.5 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) gag_pre-integrs PF13976.1 EGO29482.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 EGO29482.1 - 0.0094 16.0 0.0 0.049 13.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain TolA PF06519.6 EGO29482.1 - 0.028 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 TolA C-terminal ELL PF10390.4 EGO29483.1 - 0.0043 16.3 1.3 0.005 16.1 0.9 1.1 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL zf-met2 PF12907.2 EGO29486.1 - 1e-17 63.7 2.1 1.4e-17 63.3 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EGO29486.1 - 4.6e-06 27.2 11.6 4.6e-06 27.2 8.1 1.9 2 0 0 2 2 2 1 4F5 protein family zf-PHD-like PF15446.1 EGO29486.1 - 0.019 14.2 0.6 0.023 14.0 0.4 1.0 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Ima1_N PF09779.4 EGO29486.1 - 0.26 11.7 2.4 0.38 11.2 1.7 1.3 1 1 0 1 1 1 0 Ima1 N-terminal domain Beta_elim_lyase PF01212.16 EGO29487.1 - 3.6e-71 239.6 0.0 4.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGO29487.1 - 4.2e-06 25.9 0.0 7.2e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGO29487.1 - 0.00048 18.5 0.0 0.00076 17.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_33 PF13592.1 EGO29488.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix Spore_YtfJ PF09579.5 EGO29489.1 - 2.8 7.8 5.7 5.3 6.9 3.7 1.7 1 1 1 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) LSM PF01423.17 EGO29490.1 - 3.1e-18 65.0 1.1 4.2e-18 64.6 0.8 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO29490.1 - 0.02 14.8 0.1 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 EGO29490.1 - 0.035 13.7 1.1 0.048 13.3 0.2 1.6 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Gemin7 PF11095.3 EGO29490.1 - 0.064 12.9 0.1 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) API5 PF05918.6 EGO29490.1 - 2.2 6.6 6.8 2.9 6.2 4.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Melibiase PF02065.13 EGO29491.1 - 7.5e-15 54.5 0.4 7.7e-12 44.6 0.0 2.8 2 1 0 2 2 2 2 Melibiase Melibiase PF02065.13 EGO29492.1 - 3.1e-20 72.2 0.1 2.2e-15 56.2 0.0 3.0 2 1 0 2 2 2 2 Melibiase DDE_Tnp_4 PF13359.1 EGO29494.1 - 1.1e-08 34.8 0.1 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGO29494.1 - 0.0029 17.1 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Cys_rich_VLP PF14194.1 EGO29494.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich VLP Sec2p PF06428.6 EGO29495.1 - 0.16 11.8 4.0 0.25 11.2 2.4 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p zf-tcix PF14952.1 EGO29497.1 - 0.093 12.0 0.8 0.25 10.6 0.6 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Peptidase_C13 PF01650.13 EGO29498.1 - 9.9e-45 152.8 0.7 1.2e-44 152.5 0.5 1.1 1 0 0 1 1 1 1 Peptidase C13 family WD40 PF00400.27 EGO29499.1 - 1.3e-44 148.5 20.8 3e-11 42.7 0.2 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO29499.1 - 8.1e-07 28.1 3.8 0.064 11.9 0.3 3.9 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EGO29499.1 - 2.6e-06 25.8 7.9 0.12 10.4 1.6 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Arena_nucleocap PF00843.12 EGO29499.1 - 0.068 11.0 0.0 0.79 7.5 0.0 2.1 2 0 0 2 2 2 0 Arenavirus nucleocapsid protein PD40 PF07676.7 EGO29499.1 - 0.1 12.2 0.5 15 5.3 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 EGO29499.1 - 0.12 12.1 0.0 3.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MR_MLE_C PF13378.1 EGO29501.1 - 1.4e-16 60.4 0.1 3.2e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGO29501.1 - 7.3e-13 48.8 0.1 2.6e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGO29501.1 - 1.1e-08 35.0 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain NodS PF05401.6 EGO29502.1 - 0.13 11.6 0.0 17 4.7 0.0 2.3 2 0 0 2 2 2 0 Nodulation protein S (NodS) Retrotrans_gag PF03732.12 EGO29503.1 - 5e-07 29.7 0.2 5e-07 29.7 0.1 2.5 1 1 2 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO29503.1 - 8.4e-07 28.6 3.9 1.7e-06 27.6 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO29503.1 - 0.061 12.7 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein VanY PF02557.12 EGO29503.1 - 0.11 12.3 1.7 0.24 11.2 0.5 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Retrotrans_gag PF03732.12 EGO29504.1 - 0.00014 21.8 6.9 0.00026 20.9 2.6 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein Peptidase_M27 PF01742.12 EGO29504.1 - 0.039 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease Tet_JBP PF12851.2 EGO29506.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily GCV_H PF01597.14 EGO29510.1 - 9.1e-40 135.1 0.1 1.1e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EGO29510.1 - 3e-05 23.6 0.6 5.2e-05 22.8 0.4 1.5 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EGO29510.1 - 0.0001 21.8 0.2 0.00024 20.6 0.1 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Peptidase_M23 PF01551.17 EGO29510.1 - 0.04 13.9 0.6 1.2 9.1 0.3 2.3 1 1 1 2 2 2 0 Peptidase family M23 Tropomyosin_1 PF12718.2 EGO29511.1 - 8.9e-06 25.6 3.9 1.3e-05 25.1 2.7 1.2 1 0 0 1 1 1 1 Tropomyosin like Myosin_tail_1 PF01576.14 EGO29511.1 - 6.9e-05 20.7 4.4 8.6e-05 20.4 3.1 1.1 1 0 0 1 1 1 1 Myosin tail Spc7 PF08317.6 EGO29511.1 - 0.0034 16.0 1.1 0.0049 15.5 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Cep57_CLD PF14073.1 EGO29511.1 - 0.0072 16.1 4.6 0.011 15.5 3.2 1.3 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 DUF745 PF05335.8 EGO29511.1 - 0.0084 15.6 1.4 0.013 15.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF4472 PF14739.1 EGO29511.1 - 0.021 15.2 1.8 0.032 14.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) IncA PF04156.9 EGO29511.1 - 0.025 14.1 4.4 0.039 13.5 3.1 1.3 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EGO29511.1 - 0.059 13.3 4.2 0.11 12.5 2.9 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3375 PF11855.3 EGO29511.1 - 0.087 11.5 7.1 0.014 14.2 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Tropomyosin PF00261.15 EGO29511.1 - 0.15 11.1 7.9 0.34 9.9 5.5 1.6 1 1 0 1 1 1 0 Tropomyosin TPR_MLP1_2 PF07926.7 EGO29511.1 - 0.16 11.7 4.2 0.26 11.0 2.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.16 EGO29511.1 - 0.25 11.6 4.0 0.64 10.3 2.6 1.7 1 1 1 2 2 2 0 Spectrin repeat APG6 PF04111.7 EGO29511.1 - 0.36 9.8 5.5 0.5 9.3 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EGO29511.1 - 0.82 9.2 4.8 1.3 8.5 2.3 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Translin PF01997.11 EGO29512.1 - 9.8e-54 181.9 0.0 1.2e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Translin family Trigger_C PF05698.9 EGO29512.1 - 0.034 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Glyco_hydro_98M PF08306.6 EGO29512.1 - 0.051 12.2 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Herpes_gE PF02480.11 EGO29513.1 - 0.063 11.5 0.0 0.092 10.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Retrotrans_gag PF03732.12 EGO29515.1 - 7.4e-09 35.5 0.3 7.4e-09 35.5 0.2 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO29515.1 - 0.00038 20.2 3.0 0.0007 19.4 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle adh_short_C2 PF13561.1 EGO29516.1 - 1.9e-28 99.9 0.0 2.4e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO29516.1 - 4.2e-22 78.8 2.0 9.4e-22 77.6 1.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO29516.1 - 2.3e-12 46.9 0.4 3.7e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 KR domain FUSC_2 PF13515.1 EGO29517.1 - 2.5e-14 53.3 14.6 4.2e-14 52.5 10.1 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGO29517.1 - 1.9e-11 43.1 9.6 7e-11 41.2 6.7 1.7 1 1 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.3 EGO29517.1 - 3.3e-05 22.7 10.7 0.00011 21.0 7.4 2.0 1 1 0 1 1 1 1 Aluminium activated malate transporter DUF2422 PF10337.4 EGO29517.1 - 0.00018 20.4 0.2 0.00018 20.4 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EGO29517.1 - 0.00023 20.8 2.1 0.00036 20.2 1.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 EGO29517.1 - 0.001 18.9 6.1 0.0021 17.9 4.2 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) adh_short_C2 PF13561.1 EGO29520.1 - 5.1e-25 88.6 0.0 6.4e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO29520.1 - 4.5e-23 81.9 0.7 1.2e-22 80.5 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO29520.1 - 1.3e-10 41.2 0.3 3.4e-10 39.8 0.2 1.6 1 1 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.2 EGO29520.1 - 0.032 14.1 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family MRP-L27 PF09809.4 EGO29521.1 - 1.6e-05 24.5 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF367 PF04034.8 EGO29522.1 - 8e-47 158.0 0.0 1e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGO29522.1 - 5.5e-14 51.4 0.1 8.9e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI EIF_2_alpha PF07541.7 EGO29526.1 - 1.8e-36 124.3 0.0 4.1e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGO29526.1 - 6.5e-13 48.5 0.7 1.5e-12 47.4 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF4140 PF13600.1 EGO29526.1 - 3.9 7.9 8.4 1.5 9.3 0.9 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) BCDHK_Adom3 PF10436.4 EGO29527.1 - 1.9e-66 222.6 0.0 2.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGO29527.1 - 1.4e-19 69.8 0.0 4.6e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGO29527.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L16 PF00252.13 EGO29528.1 - 1.8e-33 115.0 0.0 2.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Hexapep PF00132.19 EGO29529.1 - 5.5e-10 38.2 19.0 0.00013 21.3 1.1 4.3 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO29529.1 - 0.00023 20.6 9.2 0.094 12.2 2.3 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF342 PF03961.8 EGO29529.1 - 0.27 9.6 2.4 0.34 9.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RTA1 PF04479.8 EGO29530.1 - 2.6e-27 95.7 3.2 3.9e-27 95.2 2.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Spc7 PF08317.6 EGO29531.1 - 0.0056 15.3 9.8 0.012 14.3 6.8 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 EGO29531.1 - 0.0086 14.5 9.8 0.013 14.0 6.8 1.3 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 EGO29531.1 - 0.11 12.0 16.2 0.07 12.7 4.6 2.4 1 1 1 2 2 2 0 IncA protein Mod_r PF07200.8 EGO29531.1 - 0.25 11.2 11.2 0.19 11.6 1.6 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.6 EGO29531.1 - 1.2 9.0 5.2 3.5 7.5 3.2 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 EGO29531.1 - 2 8.7 6.9 1.5 9.1 0.9 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 EGO29531.1 - 2.1 7.9 17.9 0.072 12.5 4.2 3.0 3 0 0 3 3 3 0 Septum formation initiator WEMBL PF05701.6 EGO29531.1 - 2.2 6.6 24.7 57 1.9 17.1 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF972 PF06156.8 EGO29531.1 - 4.3 7.7 9.9 2.4 8.5 2.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Med9 PF07544.8 EGO29531.1 - 7.2 6.4 13.9 3.2 7.5 1.0 4.1 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Kinesin PF00225.18 EGO29532.1 - 5.4e-94 314.6 0.4 5.4e-94 314.6 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain TPR_2 PF07719.12 EGO29532.1 - 0.0012 18.6 0.2 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO29532.1 - 0.0055 16.6 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO29532.1 - 0.0056 16.3 0.1 0.015 15.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO29532.1 - 0.018 15.6 0.1 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SpaB_C PF14028.1 EGO29532.1 - 0.019 14.5 0.6 0.028 13.9 0.4 1.3 1 0 0 1 1 1 0 SpaB C-terminal domain TPR_8 PF13181.1 EGO29532.1 - 0.059 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2924 PF11149.3 EGO29532.1 - 0.65 10.0 3.0 1.1 9.3 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) Phage_antitermQ PF06530.7 EGO29533.1 - 0.062 12.8 0.0 0.063 12.8 0.0 1.0 1 0 0 1 1 1 0 Phage antitermination protein Q Pkinase PF00069.20 EGO29536.1 - 8.4e-73 244.7 0.0 9.8e-73 244.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29536.1 - 5.8e-31 107.4 0.0 8.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO29536.1 - 0.00019 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO29536.1 - 0.0002 20.4 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO29536.1 - 0.0016 18.2 0.5 0.099 12.3 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family YukC PF10140.4 EGO29536.1 - 0.062 11.8 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 EGO29536.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 p450 PF00067.17 EGO29537.1 - 1.3e-57 195.3 0.0 5.4e-56 190.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO29539.1 - 1.2e-62 212.0 0.0 3.5e-62 210.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.7 EGO29541.1 - 0.14 11.8 0.2 0.14 11.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Arm PF00514.18 EGO29543.1 - 6.7e-07 28.9 0.0 0.32 10.9 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EGO29543.1 - 0.0016 17.6 0.1 0.088 11.9 0.0 2.3 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_2 PF13646.1 EGO29543.1 - 0.0088 16.3 0.1 0.076 13.2 0.0 2.5 1 1 1 2 2 2 1 HEAT repeats Proteasom_PSMB PF10508.4 EGO29543.1 - 0.016 13.4 0.1 0.023 12.9 0.1 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 EGO29545.1 - 0.042 14.1 1.2 1.3 9.3 0.8 2.3 1 1 0 1 1 1 0 HEAT repeats DUF2235 PF09994.4 EGO29547.1 - 1e-39 136.5 0.0 1.3e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sars6 PF12133.3 EGO29547.1 - 0.27 10.9 1.5 11 5.8 0.2 2.3 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus Abhydrolase_3 PF07859.8 EGO29549.1 - 7.3e-44 149.8 0.0 2.5e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO29549.1 - 4e-11 42.1 0.0 1.1e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO29549.1 - 0.00025 20.8 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGO29549.1 - 0.016 13.9 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.16 EGO29549.1 - 0.08 12.1 0.0 5.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.11 EGO29553.1 - 1.1e-41 142.7 44.1 1.1e-41 142.7 30.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO29553.1 - 6.4e-19 67.5 23.1 6.4e-19 67.5 16.0 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO29553.1 - 2.1e-12 46.3 9.1 2.1e-12 46.3 6.3 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EGO29553.1 - 0.0053 14.8 1.8 0.0083 14.2 0.4 1.9 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF983 PF06170.7 EGO29553.1 - 0.24 11.5 5.2 4.4 7.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Sec23_trunk PF04811.10 EGO29555.1 - 2.1e-47 161.5 0.0 3.4e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGO29555.1 - 1e-17 63.4 0.2 1.8e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGO29555.1 - 1.1e-17 64.2 0.1 2.8e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGO29555.1 - 4.2e-14 51.8 5.1 9.2e-14 50.7 3.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGO29555.1 - 6.9e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat STE2 PF02116.10 EGO29556.1 - 0.01 14.9 0.2 0.01 14.9 0.1 1.9 2 0 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR PFL PF02901.10 EGO29557.1 - 0.06 11.7 0.7 0.11 10.8 0.5 1.4 1 0 0 1 1 1 0 Pyruvate formate lyase Spc42p PF11544.3 EGO29557.1 - 0.1 12.5 1.9 0.24 11.3 0.1 2.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF2855 PF11017.3 EGO29558.1 - 5.6e-65 219.5 0.0 6.8e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DSPc PF00782.15 EGO29559.1 - 1.3e-24 86.2 0.0 1.9e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO29559.1 - 0.00026 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Methyltrans_SAM PF10672.4 EGO29560.1 - 0.07 11.9 0.0 0.079 11.7 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase RNA_pol_L_2 PF13656.1 EGO29562.1 - 2.9e-25 87.5 0.0 3.7e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGO29562.1 - 4.9e-09 35.1 0.0 6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_6 PF00970.19 EGO29566.1 - 5.4e-31 106.6 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO29566.1 - 2.8e-29 101.8 0.0 4.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGO29566.1 - 5.1e-05 23.2 0.0 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGO29566.1 - 0.00046 20.1 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain RRM_1 PF00076.17 EGO29568.1 - 8.7e-18 63.7 0.0 9.1e-11 41.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO29568.1 - 4.1e-17 61.7 0.0 6e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO29568.1 - 6.8e-14 51.6 0.0 1.7e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Paramyxo_PCT PF14320.1 EGO29568.1 - 0.031 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered KaiC PF06745.8 EGO29569.1 - 6e-06 25.5 0.0 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EGO29569.1 - 4.4e-05 22.6 0.0 6.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.12 EGO29569.1 - 0.0048 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGO29569.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma70_r3 PF04539.11 EGO29569.1 - 0.085 12.7 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 region 3 PIG-P PF08510.7 EGO29570.1 - 3.4e-28 97.8 4.8 4.3e-28 97.4 3.4 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 EGO29570.1 - 0.82 9.9 6.5 1.5 9.1 4.5 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-C2H2 PF00096.21 EGO29571.1 - 4.8e-10 39.1 10.4 7e-06 26.0 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO29571.1 - 1.4e-08 34.6 10.7 2.2e-05 24.5 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO29571.1 - 7.1e-08 32.2 7.6 0.00029 20.9 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO29571.1 - 7.8e-06 25.8 2.9 0.0036 17.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO29571.1 - 0.00017 21.6 5.4 0.0022 18.1 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-BED PF02892.10 EGO29571.1 - 0.003 17.2 7.2 0.14 11.9 0.9 2.3 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 EGO29571.1 - 0.021 14.6 3.5 0.024 14.5 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger DUF3455 PF11937.3 EGO29571.1 - 0.062 13.2 1.2 0.22 11.4 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3455) zf-C2HC_2 PF13913.1 EGO29571.1 - 0.087 12.5 1.9 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 EGO29571.1 - 0.18 11.5 4.4 5.1 6.8 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGO29571.1 - 0.26 10.9 4.2 8.2 6.1 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EGO29571.1 - 0.38 10.8 6.8 0.2 11.7 0.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) XPG_I PF00867.13 EGO29573.1 - 3.2e-27 94.4 0.0 6.8e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGO29573.1 - 1.4e-25 89.4 0.0 2.7e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EGO29573.1 - 1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EGO29573.1 - 0.00075 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.23 EGO29573.1 - 0.027 14.0 0.0 0.069 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO29573.1 - 0.048 13.5 0.4 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Dioxygenase_C PF00775.16 EGO29574.1 - 2.9e-49 166.8 0.0 3.7e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGO29574.1 - 8.7e-17 60.8 0.0 1.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Calsequestrin PF01216.12 EGO29574.1 - 0.081 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Calsequestrin p450 PF00067.17 EGO29576.1 - 2.8e-50 171.1 0.0 5.8e-49 166.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 HMG_box PF00505.14 EGO29578.1 - 0.00041 20.5 1.5 0.00085 19.5 0.3 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO29578.1 - 0.0027 18.0 0.8 0.0041 17.4 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain DUF4473 PF14747.1 EGO29578.1 - 0.052 13.7 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) SSPI PF14098.1 EGO29578.1 - 0.077 12.9 0.2 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Small, acid-soluble spore protein I PMEI PF04043.10 EGO29578.1 - 0.1 12.5 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor AP4E_app_platf PF14807.1 EGO29578.1 - 0.14 12.3 0.5 0.31 11.3 0.1 1.7 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform PepSY_TM_1 PF13172.1 EGO29579.1 - 4.9 7.0 7.9 2.4 8.0 3.3 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix Herpes_U47 PF05467.6 EGO29580.1 - 0.039 11.8 4.5 0.064 11.0 3.1 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 E3_binding PF02817.12 EGO29580.1 - 0.3 10.7 1.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain DUF2780 PF11075.3 EGO29581.1 - 0.088 12.8 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) DUF1680 PF07944.7 EGO29583.1 - 0.055 11.7 0.2 0.063 11.5 0.1 1.0 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Transketolase_N PF00456.16 EGO29584.1 - 0.15 10.8 0.3 0.21 10.3 0.2 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DFP PF04127.10 EGO29585.1 - 9.6e-21 74.2 0.0 1.4e-12 47.5 0.0 2.3 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Hydrophobin PF01185.13 EGO29586.1 - 7.2e-14 52.0 12.9 9.1e-14 51.6 8.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin YjbE PF11106.3 EGO29586.1 - 0.49 10.3 9.0 0.73 9.8 6.3 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Toxin_12 PF07740.7 EGO29586.1 - 7.1 7.2 8.8 6.7 7.2 0.7 2.7 3 0 0 3 3 3 0 Ion channel inhibitory toxin TPR_10 PF13374.1 EGO29587.1 - 0.04 13.8 1.2 0.093 12.6 0.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SIS PF01380.17 EGO29588.1 - 2.5e-62 208.2 0.1 2.6e-32 111.1 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EGO29588.1 - 1e-24 86.9 0.4 2.6e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGO29588.1 - 7.7e-19 67.9 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGO29588.1 - 4e-13 49.1 0.0 7.7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGO29588.1 - 5e-08 31.9 0.0 7e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EGO29588.1 - 0.0015 18.2 0.1 0.02 14.5 0.0 2.7 2 1 1 3 3 3 1 SIS domain Abhydrolase_6 PF12697.2 EGO29590.1 - 1.5e-32 113.3 7.4 7e-32 111.1 5.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO29590.1 - 2.1e-15 56.9 0.0 1.4e-12 47.6 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO29590.1 - 4.3e-11 42.7 0.2 2.4e-08 33.8 0.1 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO29590.1 - 7.6e-05 22.4 0.1 0.00031 20.5 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EGO29590.1 - 0.0078 14.7 0.1 1.3 7.3 0.0 2.2 2 0 0 2 2 2 2 Ndr family Chlorophyllase2 PF12740.2 EGO29590.1 - 0.045 12.6 0.3 0.54 9.0 0.0 2.3 2 1 1 3 3 3 0 Chlorophyllase enzyme Abhydrolase_8 PF06259.7 EGO29590.1 - 0.048 13.1 0.6 0.094 12.2 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Esterase PF00756.15 EGO29590.1 - 0.26 10.6 2.2 1.3 8.3 0.2 2.5 3 0 0 3 3 3 0 Putative esterase DUF667 PF05018.8 EGO29591.1 - 1.5e-11 43.8 0.0 0.0016 17.7 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF667) Ribosomal_L29e PF01779.12 EGO29594.1 - 0.11 12.4 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Ribosomal L29e protein family PDEase_I PF00233.14 EGO29599.1 - 3.3e-40 138.3 3.1 7.8e-37 127.2 0.1 3.0 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Methyltransf_16 PF10294.4 EGO29600.1 - 2.7e-12 46.4 0.0 4.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO29600.1 - 0.024 15.2 0.0 0.036 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MutS_V PF00488.16 EGO29601.1 - 2.9e-64 216.6 0.0 4.5e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO29601.1 - 5.9e-42 143.7 0.2 1.1e-41 142.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGO29601.1 - 1.5e-17 63.6 0.0 4.2e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGO29601.1 - 7.7e-10 38.9 0.0 3.9e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EGO29601.1 - 3.4e-05 23.9 0.8 0.00011 22.2 0.0 2.4 3 0 0 3 3 3 1 MutS family domain IV Glyco_hydro_16 PF00722.16 EGO29602.1 - 6e-35 120.2 2.4 8e-35 119.7 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EGO29602.1 - 0.014 15.3 15.5 0.031 14.2 10.7 1.5 1 0 0 1 1 1 0 Chitin recognition protein p450 PF00067.17 EGO29603.1 - 4e-22 78.3 0.0 4.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO29604.1 - 5.7e-10 38.3 0.1 6e-10 38.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 EGO29605.1 - 1.2e-12 47.2 0.0 1.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO29605.1 - 1.7e-08 34.2 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGO29605.1 - 9.1e-05 22.8 1.9 0.00033 21.0 1.3 2.0 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EGO29605.1 - 0.00056 19.7 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 EGO29605.1 - 0.0043 17.4 0.2 0.014 15.7 0.1 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4654 PF15547.1 EGO29605.1 - 0.15 12.3 1.8 0.26 11.6 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) Formyl_trans_N PF00551.14 EGO29606.1 - 5.6e-27 94.4 0.0 9.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EGO29606.1 - 7e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 EGO29607.1 - 2.1e-25 89.2 35.5 2.1e-25 89.2 24.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EGO29608.1 - 1.8e-46 154.4 22.6 1.8e-10 40.2 0.5 11.1 12 0 0 12 12 12 8 WD domain, G-beta repeat PQQ_3 PF13570.1 EGO29608.1 - 2.2e-06 27.7 10.4 0.051 13.8 0.3 5.8 5 0 0 5 5 5 2 PQQ-like domain Kelch_6 PF13964.1 EGO29608.1 - 9.1e-05 22.4 1.5 0.19 11.9 0.0 4.4 5 0 0 5 5 5 1 Kelch motif CPSF_A PF03178.10 EGO29608.1 - 0.0051 15.9 0.0 3.7 6.5 0.0 2.6 3 0 0 3 3 3 2 CPSF A subunit region Nup160 PF11715.3 EGO29608.1 - 0.0088 14.2 1.0 0.029 12.5 0.2 2.1 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGO29608.1 - 0.016 14.3 0.9 10 5.0 0.0 3.4 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Kelch_5 PF13854.1 EGO29608.1 - 0.25 11.3 2.1 57 3.8 0.1 3.8 3 0 0 3 3 3 0 Kelch motif Mad3_BUB1_I PF08311.7 EGO29609.1 - 8.7e-25 86.9 0.1 1.4e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Cupin_1 PF00190.17 EGO29611.1 - 1.1e-30 105.9 0.0 1.5e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGO29611.1 - 2.7e-26 90.8 0.3 8e-13 47.7 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGO29611.1 - 2.3e-09 36.4 0.1 0.0015 17.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EGO29611.1 - 0.00019 21.0 0.0 0.055 13.0 0.0 2.4 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.13 EGO29611.1 - 0.00024 20.7 0.0 0.0021 17.6 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EGO29611.1 - 0.001 18.7 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_8 PF13621.1 EGO29611.1 - 0.0049 16.4 0.0 0.062 12.7 0.0 2.4 2 1 0 2 2 2 1 Cupin-like domain GPI PF06560.6 EGO29611.1 - 0.044 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) RRM_1 PF00076.17 EGO29612.1 - 1.1e-33 114.7 0.0 1.3e-19 69.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO29612.1 - 8.8e-20 70.4 0.1 1e-13 51.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO29612.1 - 1.3e-12 47.3 0.0 1.1e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGO29612.1 - 4.9e-06 26.1 0.1 0.0078 15.8 0.0 3.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EGO29612.1 - 0.11 12.2 2.2 11 5.8 0.0 2.6 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM PF05172.8 EGO29612.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.11 EGO29613.1 - 5.3e-31 107.6 27.7 8e-31 107.0 19.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.6 EGO29613.1 - 3.3 7.4 11.0 0.052 13.2 1.3 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Sterol_MT_C PF08498.5 EGO29614.1 - 6.6e-26 90.0 0.0 9.6e-26 89.5 0.0 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 EGO29614.1 - 1.1e-18 67.2 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO29614.1 - 6.5e-17 61.8 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO29614.1 - 2.2e-14 53.1 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EGO29614.1 - 1.5e-13 51.2 0.0 7.4e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO29614.1 - 8.2e-13 48.4 0.0 2e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO29614.1 - 3.8e-12 46.5 0.1 1e-11 45.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO29614.1 - 6.8e-12 45.4 0.0 1.1e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO29614.1 - 1.8e-10 41.0 0.0 3.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO29614.1 - 3.8e-08 32.7 0.0 8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGO29614.1 - 4.1e-06 26.4 0.0 6.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGO29614.1 - 2.4e-05 23.7 0.1 7.1e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EGO29614.1 - 3.6e-05 23.3 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 EGO29614.1 - 0.00018 20.5 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 EGO29614.1 - 0.00069 19.2 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EGO29614.1 - 0.00096 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EGO29614.1 - 0.0029 18.4 0.0 0.011 16.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGO29614.1 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EGO29614.1 - 0.0079 15.2 0.0 0.023 13.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EGO29614.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EGO29614.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 EGO29614.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EGO29614.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rad52_Rad22 PF04098.10 EGO29616.1 - 4.7e-57 192.0 0.0 8e-57 191.2 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein p450 PF00067.17 EGO29617.1 - 6.1e-66 222.8 0.0 7.8e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PH_9 PF15410.1 EGO29623.1 - 0.00018 21.6 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain Metallophos PF00149.23 EGO29624.1 - 2.7e-44 150.9 0.1 3.4e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 EGO29625.1 - 1.2e-83 281.1 24.6 1.4e-83 280.9 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO29625.1 - 1.9e-24 86.0 36.3 7.8e-21 74.1 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO29625.1 - 3e-07 29.2 27.8 6.7e-07 28.0 1.2 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1769 PF08588.5 EGO29626.1 - 2.9e-15 55.9 0.1 5.9e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF869 PF05911.6 EGO29626.1 - 0.048 11.9 2.7 0.06 11.5 1.9 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) SR-25 PF10500.4 EGO29626.1 - 0.2 11.0 8.9 0.27 10.6 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short_C2 PF13561.1 EGO29628.1 - 2.7e-27 96.0 0.0 3.2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO29628.1 - 2e-25 89.6 1.7 3.1e-25 89.0 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO29628.1 - 2.7e-15 56.4 0.5 3.7e-15 56.0 0.3 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGO29628.1 - 3.5e-06 25.9 0.1 4.5e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO29628.1 - 3e-05 23.5 0.1 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO29628.1 - 0.0013 17.7 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 EGO29628.1 - 0.0045 17.3 0.1 0.0091 16.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase His_biosynth PF00977.16 EGO29628.1 - 0.0062 15.8 0.1 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein 3HCDH_N PF02737.13 EGO29628.1 - 0.028 14.0 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGO29628.1 - 0.03 13.9 0.1 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DEAD PF00270.24 EGO29629.1 - 1e-40 139.0 0.7 1.5e-40 138.4 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO29629.1 - 8.9e-24 83.1 0.1 2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA PF00004.24 EGO29629.1 - 0.018 15.2 0.1 0.9 9.7 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CMS1 PF14617.1 EGO29629.1 - 0.019 14.0 0.1 0.047 12.7 0.1 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Terpene_synth_C PF03936.11 EGO29630.1 - 6.6e-18 64.8 0.1 9.9e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.1 EGO29630.1 - 0.04 13.7 0.1 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal UPF0113 PF03657.8 EGO29630.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0113) AsiA PF09010.5 EGO29630.1 - 0.14 12.0 1.2 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 Anti-Sigma Factor A MFS_1 PF07690.11 EGO29631.1 - 5.2e-26 91.1 26.9 5.5e-20 71.3 4.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO29631.1 - 3.4e-06 25.8 4.0 3.4e-06 25.8 2.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGO29631.1 - 0.012 15.3 0.3 0.012 15.3 0.2 2.8 3 0 0 3 3 3 0 MFS_1 like family WD40 PF00400.27 EGO29632.1 - 2.5e-13 49.3 20.1 0.029 14.2 0.1 8.3 10 0 0 10 10 10 5 WD domain, G-beta repeat PD40 PF07676.7 EGO29632.1 - 0.028 14.1 0.1 17 5.1 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Sdh5 PF03937.11 EGO29633.1 - 5.8e-28 96.4 0.6 6.7e-28 96.1 0.4 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Gly_transf_sug PF04488.10 EGO29634.1 - 2.6e-06 27.7 0.0 4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGO29634.1 - 0.0041 16.3 0.1 0.006 15.7 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein F-box-like PF12937.2 EGO29635.1 - 3.9e-06 26.4 3.5 3.9e-06 26.4 2.4 3.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EGO29635.1 - 0.017 14.7 11.6 0.31 10.7 0.9 4.7 5 0 0 5 5 5 0 F-box domain gag-asp_proteas PF13975.1 EGO29636.1 - 3.8e-06 26.6 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO29636.1 - 1.1e-05 25.8 0.0 1.4e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO29636.1 - 0.00029 20.7 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EGO29637.1 - 5.5e-07 29.5 1.2 5.5e-07 29.5 0.8 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO29638.1 - 1.1e-06 28.1 1.4 2.5e-06 27.1 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO29638.1 - 4.1e-05 23.2 5.5 6.8e-05 22.6 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO29638.1 - 0.24 10.9 3.6 0.44 10.0 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger WD40 PF00400.27 EGO29642.1 - 1e-58 193.2 16.0 2.8e-11 42.8 0.1 13.0 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EGO29642.1 - 2.4e-26 91.7 0.0 3.7e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGO29642.1 - 1.7e-05 23.1 0.1 0.11 10.5 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGO29642.1 - 6.1e-05 22.5 0.8 0.43 10.0 0.2 4.1 3 1 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EGO29642.1 - 0.0017 17.9 2.4 14 5.5 0.0 6.1 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EGO29642.1 - 0.13 11.9 0.0 2.9 7.5 0.0 2.8 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term DUF2096 PF09869.4 EGO29642.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) IKI3 PF04762.7 EGO29642.1 - 0.14 9.9 0.0 6.6 4.4 0.0 2.7 2 1 0 2 2 2 0 IKI3 family DEAD PF00270.24 EGO29645.1 - 6.3e-40 136.4 0.1 2.1e-19 69.6 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO29645.1 - 7.2e-25 86.6 0.0 8.6e-24 83.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO29645.1 - 2.2e-06 27.6 0.0 7.5e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RanBP PF00641.13 EGO29646.1 - 0.11 11.6 0.3 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Pkinase PF00069.20 EGO29647.1 - 5.1e-68 229.0 0.0 6e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29647.1 - 2.4e-27 95.6 0.0 3.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO29647.1 - 1.3e-06 27.5 0.0 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGO29647.1 - 0.00056 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGO29647.1 - 0.0041 16.2 0.3 0.01 14.9 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO29647.1 - 0.0074 16.0 0.3 0.12 12.0 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family TcdB_toxin_midN PF12256.3 EGO29647.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region YukC PF10140.4 EGO29647.1 - 0.078 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Glutaredoxin PF00462.19 EGO29650.1 - 1.1e-17 63.7 0.0 3.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Herpes_ori_bp PF02399.10 EGO29650.1 - 0.032 12.2 0.0 0.035 12.0 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Sec62 PF03839.11 EGO29651.1 - 2.8e-44 151.2 5.0 4.3e-44 150.6 2.1 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 p450 PF00067.17 EGO29652.1 - 9e-77 258.5 0.0 1.2e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rad17 PF03215.10 EGO29654.1 - 2.3e-56 191.6 0.0 6.2e-56 190.1 0.0 1.6 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGO29654.1 - 0.00081 20.1 0.0 0.0034 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO29654.1 - 0.0055 16.9 0.0 0.019 15.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO29654.1 - 0.042 13.8 0.3 0.95 9.4 0.2 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EGO29654.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EGO29654.1 - 0.12 11.9 0.2 0.38 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO29654.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain MBA1 PF07961.6 EGO29655.1 - 2.1e-05 23.4 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EGO29655.1 - 0.019 14.9 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 Tim44-like domain Med3 PF11593.3 EGO29655.1 - 0.28 10.4 12.3 0.3 10.2 8.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GST_N_3 PF13417.1 EGO29656.1 - 1.1e-17 63.9 0.0 2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO29656.1 - 3.1e-17 62.3 0.0 4.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO29656.1 - 5.8e-14 52.0 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO29656.1 - 1.5e-10 40.9 0.0 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO29656.1 - 1.8e-09 37.3 0.0 3.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO29656.1 - 0.0025 18.2 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO29658.1 - 1.3e-16 60.3 0.0 1.9e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO29658.1 - 6.3e-15 55.1 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO29658.1 - 4.2e-14 52.4 0.0 1.2e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO29658.1 - 3e-10 39.9 0.0 5.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO29658.1 - 2.2e-09 37.0 0.0 4.2e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO29658.1 - 0.00018 21.9 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO29659.1 - 3.6e-17 62.3 0.0 1.6e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO29659.1 - 7e-16 58.1 0.0 2.1e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO29659.1 - 3e-15 55.9 0.0 5.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO29659.1 - 4.1e-11 42.6 0.0 8.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO29659.1 - 6.1e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO29659.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HAD_2 PF13419.1 EGO29660.1 - 1.4e-07 31.9 0.0 3.2e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase p450 PF00067.17 EGO29661.1 - 3e-72 243.6 0.0 1.2e-71 241.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_47 PF01532.15 EGO29662.1 - 1.7e-110 369.7 0.6 1.5e-78 264.4 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 DUF1832 PF08870.6 EGO29662.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) DDE_Tnp_1_6 PF13751.1 EGO29663.1 - 8.2 6.4 9.0 0.21 11.5 0.5 2.6 3 0 0 3 3 3 0 Transposase DDE domain Sec20 PF03908.8 EGO29664.1 - 1.8e-16 59.5 2.7 1.8e-16 59.5 1.9 2.2 2 0 0 2 2 2 1 Sec20 L1R_F9L PF02442.12 EGO29664.1 - 0.034 13.6 0.4 0.071 12.5 0.2 1.6 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses End3 PF12761.2 EGO29664.1 - 0.042 13.4 0.6 0.042 13.4 0.4 2.4 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 NPV_P10 PF05531.7 EGO29664.1 - 0.094 12.9 8.7 0.21 11.8 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 EGO29664.1 - 0.21 11.5 2.6 0.37 10.7 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein Ran-binding PF05508.6 EGO29664.1 - 0.46 9.3 5.5 0.22 10.4 1.0 2.0 2 0 0 2 2 2 0 RanGTP-binding protein TSC22 PF01166.13 EGO29664.1 - 0.86 9.6 4.4 4 7.4 1.9 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family Muted PF14942.1 EGO29664.1 - 1.2 8.9 6.0 3.8 7.3 0.5 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TBPIP PF07106.8 EGO29664.1 - 3.3 7.2 9.3 0.95 8.9 1.6 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin-6_N PF09177.6 EGO29664.1 - 4.2 7.8 11.5 24 5.3 0.4 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PHD PF00628.24 EGO29665.1 - 3.7e-09 36.1 4.4 6.6e-09 35.3 3.0 1.4 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.19 EGO29665.1 - 2.4e-05 23.9 0.1 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 EGO29665.1 - 0.018 14.3 1.9 0.034 13.4 1.3 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EGO29665.1 - 0.069 12.8 1.0 0.15 11.8 0.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EGO29665.1 - 0.74 9.5 6.8 0.15 11.8 1.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DNA_pol_viral_N PF00242.12 EGO29666.1 - 0.36 9.7 4.9 0.4 9.6 3.4 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ADIP PF11559.3 EGO29666.1 - 0.72 9.7 8.0 2.9 7.7 3.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4470 PF14737.1 EGO29667.1 - 2.7e-22 78.3 0.0 5.2e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGO29667.1 - 3.3e-10 39.6 12.0 7.7e-10 38.4 8.3 1.7 1 0 0 1 1 1 1 MYND finger DUF4413 PF14372.1 EGO29667.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DZR PF12773.2 EGO29668.1 - 0.12 12.2 3.9 0.34 10.7 2.7 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGO29668.1 - 0.25 10.6 6.5 1 8.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_3 PF13917.1 EGO29668.1 - 0.26 11.0 4.0 0.64 9.7 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_2 PF13240.1 EGO29668.1 - 0.57 9.7 4.3 0.69 9.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 EGO29668.1 - 1.8 8.1 5.6 3.4 7.2 3.9 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF4219 PF13961.1 EGO29669.1 - 0.095 12.1 0.6 0.22 11.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 EGO29670.1 - 0.025 14.2 2.0 0.043 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGO29670.1 - 0.092 12.4 0.9 0.88 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle CD24 PF14984.1 EGO29670.1 - 1.6 8.5 8.7 3.6 7.4 6.0 1.6 1 0 0 1 1 1 0 CD24 protein DUF4470 PF14737.1 EGO29671.1 - 2.4e-23 81.7 0.0 4.8e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGO29671.1 - 2.1e-10 40.2 13.3 5.3e-10 39.0 9.2 1.7 1 0 0 1 1 1 1 MYND finger DUF4413 PF14372.1 EGO29671.1 - 0.04 13.9 0.0 0.78 9.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) Ecl1 PF12855.2 EGO29671.1 - 6.8 6.0 8.3 1.5 8.1 3.0 2.0 2 0 0 2 2 2 0 Life-span regulatory factor FMO-like PF00743.14 EGO29672.1 - 2.8e-31 108.3 0.0 4.6e-18 64.7 0.0 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO29672.1 - 1.7e-09 38.0 0.0 8e-09 35.8 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO29672.1 - 0.00019 20.5 0.0 0.0094 14.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO29672.1 - 0.01 15.6 0.2 9 6.0 0.0 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding zf-C3HC4_3 PF13920.1 EGO29673.1 - 5.1e-13 48.4 8.1 5.1e-13 48.4 5.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGO29673.1 - 5.3e-07 29.4 3.9 5.3e-07 29.4 2.7 3.0 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 EGO29673.1 - 5.3e-07 29.5 8.0 5.3e-07 29.5 5.5 2.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO29673.1 - 2.8e-05 23.6 8.4 2.8e-05 23.6 5.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO29673.1 - 4e-05 23.3 6.8 4e-05 23.3 4.7 2.6 2 1 0 2 2 2 1 Ring finger domain Armet PF10208.4 EGO29673.1 - 0.00013 21.6 0.1 0.26 10.9 0.0 2.4 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding UPF0547 PF10571.4 EGO29673.1 - 0.0019 17.8 12.7 0.27 10.9 1.1 3.2 2 1 0 2 2 2 2 Uncharacterised protein family UPF0547 FYVE_2 PF02318.11 EGO29673.1 - 0.0019 18.0 2.4 0.0019 18.0 1.7 3.0 3 0 0 3 3 2 1 FYVE-type zinc finger zf-P11 PF03854.9 EGO29673.1 - 0.0032 16.9 4.2 0.0032 16.9 2.9 3.1 3 1 0 3 3 3 1 P-11 zinc finger Rho_N PF07498.7 EGO29673.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF4518 PF15008.1 EGO29673.1 - 0.32 9.9 2.8 1.1 8.1 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) zf-RING_5 PF14634.1 EGO29673.1 - 0.42 10.3 21.7 0.039 13.6 4.9 2.6 2 0 0 2 2 2 0 zinc-RING finger domain DUF1682 PF07946.9 EGO29673.1 - 0.87 8.3 5.7 1.4 7.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Prok-RING_4 PF14447.1 EGO29673.1 - 2 8.0 9.0 0.07 12.6 1.8 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Dicty_REP PF05086.7 EGO29673.1 - 2.1 5.9 4.3 3.3 5.3 3.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_4 PF14570.1 EGO29673.1 - 2.7 7.6 19.2 0.59 9.7 3.7 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DNA_RNApol_7kD PF03604.8 EGO29673.1 - 9.7 5.7 10.3 0.42 10.1 1.5 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF221 PF02714.10 EGO29674.1 - 7e-99 330.7 16.9 7e-99 330.7 11.7 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO29674.1 - 6.3e-36 123.3 5.5 1.8e-35 121.8 3.8 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGO29674.1 - 9.7e-14 51.0 0.1 2.3e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGO29674.1 - 9.8e-12 45.2 0.1 1.6e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2828 PF11443.3 EGO29674.1 - 0.38 8.8 0.1 0.57 8.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ran-binding PF05508.6 EGO29675.1 - 0.065 12.1 0.0 0.068 12.0 0.0 1.0 1 0 0 1 1 1 0 RanGTP-binding protein Glyco_hydro_72 PF03198.9 EGO29676.1 - 5.2e-96 321.3 0.1 6.8e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGO29676.1 - 1.3e-20 73.6 4.3 3.6e-20 72.2 3.0 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EGO29676.1 - 0.0071 15.5 0.1 0.016 14.4 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 EGO29677.1 - 2.7e-102 342.6 0.0 5.1e-56 190.1 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 MCR_gamma PF02240.11 EGO29677.1 - 0.14 11.2 0.1 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase gamma subunit VPS11_C PF12451.3 EGO29677.1 - 0.17 11.8 2.6 12 5.8 0.2 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal SLAC1 PF03595.12 EGO29677.1 - 0.17 10.4 0.1 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel PPE PF00823.14 EGO29677.1 - 0.45 10.3 0.3 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 PPE family Syntaxin-6_N PF09177.6 EGO29678.1 - 1.2e-22 80.0 4.6 5.1e-22 78.1 0.2 2.6 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGO29678.1 - 1.7e-14 53.2 3.4 1.7e-14 53.2 2.4 2.4 3 0 0 3 3 2 1 SNARE domain zf-C4H2 PF10146.4 EGO29678.1 - 7.8e-05 22.8 0.7 7.8e-05 22.8 0.5 1.6 1 1 1 2 2 2 1 Zinc finger-containing protein FlaC_arch PF05377.6 EGO29678.1 - 0.0015 18.3 3.0 0.83 9.5 0.1 3.7 3 1 1 4 4 4 1 Flagella accessory protein C (FlaC) HisKA_3 PF07730.8 EGO29678.1 - 0.0035 17.6 0.4 0.0035 17.6 0.3 3.1 2 1 0 2 2 2 1 Histidine kinase HisKA PF00512.20 EGO29678.1 - 0.0061 16.5 0.6 0.0061 16.5 0.4 2.6 2 2 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Laminin_II PF06009.7 EGO29678.1 - 0.028 14.1 2.0 0.92 9.2 0.0 2.4 2 1 0 2 2 2 0 Laminin Domain II IFT57 PF10498.4 EGO29678.1 - 0.033 12.9 3.4 1.1 7.9 0.2 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FliJ PF02050.11 EGO29678.1 - 0.043 13.8 6.9 1.8 8.6 0.9 3.0 2 1 1 3 3 3 0 Flagellar FliJ protein DUF3040 PF11239.3 EGO29678.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Use1 PF09753.4 EGO29678.1 - 0.067 12.6 3.6 0.078 12.3 0.2 2.1 1 1 0 2 2 2 0 Membrane fusion protein Use1 DUF2360 PF10152.4 EGO29678.1 - 0.068 13.4 1.4 0.13 12.5 1.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Prominin PF05478.6 EGO29678.1 - 0.096 10.2 0.1 0.45 7.9 0.0 1.9 2 0 0 2 2 2 0 Prominin Microtub_assoc PF07989.6 EGO29678.1 - 0.13 12.1 1.1 1.8 8.4 0.0 2.7 2 1 0 2 2 2 0 Microtubule associated DUF641 PF04859.7 EGO29678.1 - 0.26 11.0 7.4 0.25 11.1 0.3 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) COG2 PF06148.6 EGO29678.1 - 0.28 11.0 3.1 29 4.5 0.0 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 EGO29678.1 - 0.41 10.2 3.0 0.96 9.0 0.1 2.2 2 0 0 2 2 2 0 Mnd1 family DUF1664 PF07889.7 EGO29678.1 - 0.43 10.3 3.3 7.5 6.3 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EGO29678.1 - 0.56 8.8 4.2 2.6 6.6 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_I PF06008.9 EGO29678.1 - 0.61 9.3 6.1 0.78 9.0 0.3 2.5 2 1 0 2 2 2 0 Laminin Domain I DUF3584 PF12128.3 EGO29678.1 - 0.75 7.0 4.7 0.89 6.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EGO29678.1 - 0.89 8.4 5.8 1.1 8.1 0.7 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EGO29678.1 - 1.2 8.9 6.4 8.9 6.1 0.6 2.6 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EGO29678.1 - 1.9 8.9 5.2 10 6.5 0.3 3.6 3 2 1 4 4 4 0 SlyX DUF4140 PF13600.1 EGO29678.1 - 7.8 7.0 10.7 1.5 9.2 0.3 3.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Cortex-I_coil PF09304.5 EGO29678.1 - 8.6 6.4 10.7 9.7 6.2 0.2 3.0 2 1 1 3 3 3 0 Cortexillin I, coiled coil CCDC-167 PF15188.1 EGO29678.1 - 9.6 6.2 9.1 4.6 7.2 0.6 3.1 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4470 PF14737.1 EGO29679.1 - 1.3e-13 50.5 0.0 8.4e-13 47.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGO29679.1 - 2.3e-06 27.3 10.1 9.3e-06 25.4 7.0 2.2 1 0 0 1 1 1 1 MYND finger ADH_N PF08240.7 EGO29681.1 - 6.5e-29 99.8 1.9 1.1e-28 99.1 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO29681.1 - 9.3e-29 99.6 0.7 1.5e-28 98.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO29681.1 - 5.5e-05 24.0 0.2 8.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MerT PF02411.10 EGO29681.1 - 0.11 12.2 0.3 0.37 10.6 0.2 1.9 1 0 0 1 1 1 0 MerT mercuric transport protein Fer4_8 PF13183.1 EGO29681.1 - 5.4 7.1 7.5 1.8 8.6 0.9 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA PF00004.24 EGO29682.1 - 3.2e-19 69.4 0.0 4.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO29682.1 - 3e-06 27.4 1.0 0.00037 20.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO29682.1 - 9.1e-06 26.5 0.0 1.1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO29682.1 - 6.2e-05 22.7 0.4 0.00074 19.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGO29682.1 - 8.6e-05 22.2 0.3 0.00026 20.6 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EGO29682.1 - 0.00019 21.4 0.5 0.00035 20.6 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGO29682.1 - 0.00027 20.8 0.0 0.00033 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO29682.1 - 0.00074 19.8 0.0 0.0012 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGO29682.1 - 0.0016 18.3 0.2 0.0031 17.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO29682.1 - 0.0056 16.5 0.0 0.0073 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EGO29682.1 - 0.0082 15.7 0.1 0.027 14.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGO29682.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EGO29682.1 - 0.016 14.7 0.0 0.055 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 EGO29682.1 - 0.017 14.6 0.0 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EGO29682.1 - 0.026 13.5 0.0 0.051 12.5 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EGO29682.1 - 0.028 13.1 0.1 0.25 10.0 0.0 1.9 1 1 1 2 2 2 0 TIP49 C-terminus AAA_2 PF07724.9 EGO29682.1 - 0.038 13.8 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Torsin PF06309.6 EGO29682.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_3 PF07726.6 EGO29682.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGO29682.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 EGO29682.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.5 EGO29682.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 p450 PF00067.17 EGO29683.1 - 2.5e-62 210.9 0.0 3.4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SWIRM PF04433.12 EGO29684.1 - 3.9e-36 123.0 0.0 6.2e-35 119.1 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EGO29684.1 - 8.4e-11 41.2 2.7 1.4e-10 40.5 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EGO29684.1 - 3e-09 36.8 0.0 7.3e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO29684.1 - 5.4e-08 32.7 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chordopox_RPO7 PF05864.7 EGO29684.1 - 0.38 10.8 2.2 3 8.0 0.4 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PPR_3 PF13812.1 EGO29685.1 - 8e-16 56.9 1.0 6e-05 23.0 0.0 6.4 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 EGO29685.1 - 5.3e-09 35.4 0.0 0.23 11.4 0.0 5.7 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.1 EGO29685.1 - 2.5e-08 33.7 0.0 0.27 11.2 0.0 5.2 4 1 1 5 5 5 2 PPR repeat family PPR_1 PF12854.2 EGO29685.1 - 0.0036 16.7 1.0 0.58 9.6 0.0 3.7 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.1 EGO29685.1 - 0.012 16.2 5.0 0.51 11.1 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EGO29687.1 - 5.1e-69 232.3 0.0 7.2e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29687.1 - 3.6e-32 111.4 0.0 6.2e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO29687.1 - 0.00041 20.1 0.0 0.0015 18.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGO29687.1 - 0.25 10.0 0.1 0.5 9.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C3HC4_3 PF13920.1 EGO29688.1 - 4.3e-11 42.2 5.3 1.7e-09 37.2 0.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO29688.1 - 1.2e-05 25.2 6.2 1.3e-05 25.0 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO29688.1 - 0.0052 16.4 3.5 0.037 13.7 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO29688.1 - 0.078 12.8 11.3 0.11 12.3 5.4 2.6 2 1 1 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.1 EGO29688.1 - 3.4 7.2 6.1 0.69 9.5 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L18e PF00828.14 EGO29689.1 - 4.4e-35 120.8 0.1 6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 EGO29690.1 - 3.1e-24 84.1 0.0 4.1e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGO29690.1 - 1.6e-11 43.1 0.0 2.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MMR_HSR1 PF01926.18 EGO29691.1 - 9.8e-11 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO29691.1 - 0.0012 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGO29691.1 - 0.004 16.4 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 EGO29691.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 EGO29691.1 - 0.027 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EGO29691.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGO29691.1 - 0.029 14.6 0.5 0.07 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EGO29691.1 - 0.039 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_17 PF13207.1 EGO29691.1 - 0.041 14.6 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO29691.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.13 EGO29691.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin MobB PF03205.9 EGO29691.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.18 EGO29691.1 - 0.12 11.1 0.0 0.25 10.1 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family Dynamin_N PF00350.18 EGO29691.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Dynamin family DUF1639 PF07797.9 EGO29692.1 - 0.021 14.2 1.5 0.021 14.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) YhhN PF07947.9 EGO29694.1 - 0.09 12.1 2.5 0.14 11.5 1.4 1.6 1 1 1 2 2 2 0 YhhN-like protein HLH PF00010.21 EGO29695.1 - 8.4e-08 31.7 0.0 3.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2664 PF10867.3 EGO29695.1 - 0.17 12.5 2.0 1.1 9.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) TMEM171 PF15471.1 EGO29695.1 - 5.6 5.6 6.4 9.6 4.8 1.9 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 RRM_1 PF00076.17 EGO29696.1 - 1.7e-12 46.7 0.0 3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO29696.1 - 2.9e-09 36.7 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO29696.1 - 0.00049 19.8 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGO29696.1 - 0.031 14.7 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 EGO29696.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family 6PF2K PF01591.13 EGO29697.1 - 1.7e-60 203.8 0.0 2.7e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGO29697.1 - 1.1e-23 84.0 0.1 2e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGO29697.1 - 0.00011 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO29697.1 - 0.00084 20.1 0.6 0.0042 17.8 0.2 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EGO29697.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 EGO29697.1 - 0.064 12.9 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF155 PF02582.9 EGO29698.1 - 1e-45 155.8 0.0 1.8e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 EGO29698.1 - 0.097 12.8 0.0 0.86 9.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 LSM PF01423.17 EGO29699.1 - 1.9e-15 56.1 0.2 2.3e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EGO29699.1 - 0.05 13.1 0.0 0.064 12.8 0.0 1.3 1 1 0 1 1 1 0 Repressor of phase-1 flagellin TPT PF03151.11 EGO29700.1 - 9.3e-24 83.8 8.5 9.3e-24 83.8 5.9 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGO29700.1 - 0.00014 20.9 11.8 0.0012 17.7 2.5 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EGO29700.1 - 0.0041 17.1 7.2 0.0041 17.1 5.0 2.6 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EGO29700.1 - 0.018 15.2 20.9 0.13 12.5 3.3 3.1 2 1 1 3 3 3 0 Multidrug resistance efflux transporter DUF1118 PF06549.7 EGO29700.1 - 4.9 7.3 9.5 0.22 11.6 2.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1118) DUF563 PF04577.9 EGO29701.1 - 3.1e-08 33.7 0.0 4.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Histone PF00125.19 EGO29702.1 - 1.6e-26 92.2 0.0 2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO29702.1 - 1.7e-06 28.0 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP-synt_10 PF05176.9 EGO29703.1 - 1.6e-66 224.1 0.0 2e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Sec23_trunk PF04811.10 EGO29704.1 - 4.9e-70 235.6 0.0 7.9e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGO29704.1 - 1e-22 79.4 0.1 2.2e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGO29704.1 - 3.2e-17 62.8 0.0 8.8e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGO29704.1 - 8.9e-17 60.3 8.1 1.6e-16 59.5 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGO29704.1 - 3.4e-10 39.4 0.0 6.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 EGO29704.1 - 1.3e-05 24.9 0.4 1.3e-05 24.9 0.3 2.3 2 0 0 2 2 2 1 WW domain MFS_1 PF07690.11 EGO29705.1 - 3.7e-16 58.7 46.9 5.2e-11 41.8 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO29705.1 - 7.4e-05 21.3 6.8 7.4e-05 21.3 4.7 2.8 2 1 0 3 3 3 1 MFS/sugar transport protein DUF1228 PF06779.9 EGO29705.1 - 1.2 9.2 13.3 0.66 10.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) PITH PF06201.8 EGO29706.1 - 8.9e-36 122.9 0.0 1e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain GAGE PF05831.6 EGO29707.1 - 0.15 12.1 3.5 0.23 11.5 0.1 2.3 1 1 1 2 2 2 0 GAGE protein Transp_cyt_pur PF02133.10 EGO29708.1 - 7.6e-146 486.1 41.6 8.7e-146 485.9 28.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RmlD_sub_bind PF04321.12 EGO29710.1 - 1.9e-50 171.3 0.0 2.3e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGO29710.1 - 4.8e-23 81.8 0.0 6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO29710.1 - 9.1e-08 32.3 0.0 1.1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO29710.1 - 1.4e-05 24.2 0.0 0.00044 19.2 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGO29710.1 - 3.4e-05 22.8 0.0 0.0056 15.6 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EGO29710.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Arrestin_N PF00339.24 EGO29712.1 - 0.0027 17.5 1.0 0.051 13.3 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps16_C PF04840.7 EGO29713.1 - 2.5e-81 273.0 0.1 3.8e-81 272.4 0.1 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 EGO29713.1 - 2.1e-80 270.2 0.0 2.7e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region EXS PF03124.9 EGO29715.1 - 3.3e-33 115.1 7.1 3.7e-33 115.0 4.9 1.0 1 0 0 1 1 1 1 EXS family BTB PF00651.26 EGO29720.1 - 3.7e-07 30.1 0.0 6.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EGO29721.1 - 4.9e-11 42.5 0.0 8.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rotamase_3 PF13616.1 EGO29722.1 - 3.3e-19 69.2 0.4 6.8e-19 68.2 0.2 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGO29722.1 - 8.4e-19 68.1 1.6 1.9e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EGO29722.1 - 2.9e-07 31.1 1.6 1.7e-06 28.6 1.1 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF4638 PF15472.1 EGO29722.1 - 0.93 9.0 3.7 1 8.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PIG-S PF10510.4 EGO29724.1 - 2.6e-114 382.7 6.0 1e-103 347.8 0.7 2.0 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein CLTH PF10607.4 EGO29725.1 - 1.2e-31 109.3 1.0 2.2e-31 108.4 0.7 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGO29725.1 - 0.0013 18.4 0.2 0.0064 16.1 0.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger HlyIII PF03006.15 EGO29726.1 - 6.5e-56 189.2 19.2 8.2e-56 188.8 13.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EGO29726.1 - 0.32 10.9 5.9 7.5 6.5 3.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF962) DUF3483 PF11982.3 EGO29726.1 - 0.99 8.6 7.2 0.36 10.1 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3483) p450 PF00067.17 EGO29727.1 - 5.8e-33 114.1 0.0 1.2e-32 113.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Cofilin_ADF PF00241.15 EGO29728.1 - 2.8e-18 66.0 0.0 3.1e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.19 EGO29729.1 - 1.7e-16 60.0 0.0 2.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGO29729.1 - 6.1e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO29729.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO29729.1 - 1.3e-05 25.2 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO29729.1 - 0.0063 16.3 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO29729.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EGO29729.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGO29729.1 - 0.051 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAC PF01849.13 EGO29730.1 - 1.5e-21 75.6 0.0 2.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 NAC domain XPG_I PF00867.13 EGO29731.1 - 5.5e-17 61.6 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGO29731.1 - 4.1e-08 33.4 0.0 7.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EGO29731.1 - 0.0036 17.5 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Coatomer_WDAD PF04053.9 EGO29732.1 - 1.8e-139 465.3 0.0 6.1e-139 463.6 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EGO29732.1 - 3.7e-99 332.1 0.0 5.3e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGO29732.1 - 1e-58 193.2 13.1 4.5e-10 39.0 0.1 9.5 11 0 0 11 11 11 6 WD domain, G-beta repeat TPR_14 PF13428.1 EGO29732.1 - 0.011 16.3 4.7 4.1 8.3 0.4 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Nup160 PF11715.3 EGO29732.1 - 0.012 13.7 2.6 0.49 8.4 0.0 3.6 1 1 4 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO29732.1 - 0.02 13.6 0.2 2.9 6.5 0.0 3.5 3 2 2 5 5 5 0 Nup133 N terminal like Apc4_WD40 PF12894.2 EGO29732.1 - 0.047 13.1 0.0 24 4.5 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.15 EGO29732.1 - 0.1 12.1 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_16 PF13432.1 EGO29732.1 - 5 7.9 9.7 3.5 8.3 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat GHL13 PF14883.1 EGO29733.1 - 0.0048 16.1 0.2 0.0065 15.6 0.1 1.3 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 DUF4235 PF14019.1 EGO29733.1 - 0.061 13.1 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Afi1 PF07792.7 EGO29734.1 - 3.7e-40 137.2 0.0 7.8e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EGO29734.1 - 4e-29 100.6 0.0 7.4e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGO29734.1 - 0.00075 18.0 0.0 0.051 12.0 0.0 3.2 3 1 0 3 3 3 1 Transport protein Avl9 DUF2201_N PF13203.1 EGO29737.1 - 1.4 7.9 5.2 1.6 7.8 3.6 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Period_C PF12114.3 EGO29737.1 - 2.5 7.6 6.0 3.7 7.1 4.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF1075 PF06388.6 EGO29737.1 - 3.2 7.4 4.7 0.91 9.1 1.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) NDUFA12 PF05071.11 EGO29739.1 - 8.9e-09 35.7 0.4 1.7e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PCI PF01399.22 EGO29740.1 - 1.7e-22 79.6 0.3 5.5e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EGO29740.1 - 1e-17 64.2 0.2 1e-17 64.2 0.2 2.8 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 EGO29740.1 - 0.025 14.3 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EGO29740.1 - 0.052 13.4 3.0 4.8 7.1 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO29740.1 - 0.18 11.8 2.7 0.42 10.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribophorin_II PF05817.9 EGO29741.1 - 1e-27 96.6 0.0 1.2e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4232 PF14016.1 EGO29741.1 - 0.1 12.2 0.1 1.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) TruB_N PF01509.13 EGO29742.1 - 2.2e-43 147.9 0.0 6.6e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Myb_DNA-bind_3 PF12776.2 EGO29747.1 - 3.3e-07 30.8 0.1 4.2e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Aldo_ket_red PF00248.16 EGO29749.1 - 1.3e-70 237.5 0.0 1.4e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.19 EGO29750.1 - 5.4e-19 68.0 0.0 1.4e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EGO29750.1 - 6e-13 48.6 0.2 2.4e-12 46.6 0.3 1.7 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_9 PF14604.1 EGO29750.1 - 3.2e-06 26.6 0.1 6.7e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO29750.1 - 4.4e-05 22.7 0.0 8.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO29750.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain hSH3 PF14603.1 EGO29750.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain CUE PF02845.11 EGO29751.1 - 5.1e-05 22.6 0.1 0.00047 19.5 0.0 2.6 1 1 0 1 1 1 1 CUE domain Homeobox_KN PF05920.6 EGO29751.1 - 1.4 8.7 3.7 12 5.6 0.2 2.7 2 0 0 2 2 2 0 Homeobox KN domain Cation_efflux PF01545.16 EGO29752.1 - 0.021 13.9 0.5 0.039 13.0 0.4 1.5 1 0 0 1 1 1 0 Cation efflux family ABC_tran PF00005.22 EGO29755.1 - 1.1e-19 71.0 0.6 6.2e-09 36.2 0.1 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO29755.1 - 8.7e-08 32.4 0.1 0.0052 16.7 0.0 2.9 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EGO29755.1 - 3.8e-06 26.2 0.7 0.0035 16.5 0.1 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EGO29755.1 - 0.001 18.9 0.0 1.5 8.7 0.0 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGO29755.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO29755.1 - 0.0034 17.2 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EGO29755.1 - 0.0043 17.5 0.0 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 EGO29755.1 - 0.019 14.0 0.3 3.5 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 EGO29755.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 EGO29755.1 - 0.029 14.0 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGO29755.1 - 0.04 13.4 0.1 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EGO29755.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lactococcin PF04369.8 EGO29755.1 - 0.075 12.9 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Lactococcin-like family DUF258 PF03193.11 EGO29755.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGO29755.1 - 0.11 12.8 2.0 0.19 12.0 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGO29755.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO29755.1 - 0.13 12.2 0.1 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 EGO29755.1 - 0.14 10.6 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 EGO29758.1 - 3.6e-70 236.0 0.0 4.1e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EGO29759.1 - 8e-48 162.6 0.0 9.5e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.15 EGO29760.1 - 4.6e-32 111.3 0.0 5.4e-31 107.8 0.0 2.2 2 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 EGO29761.1 - 6e-16 58.8 0.0 8.6e-15 55.0 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO29761.1 - 2.4e-07 30.7 0.0 1.1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO29761.1 - 4.3e-05 23.2 0.0 7.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGO29761.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TFIIE_alpha PF02002.12 EGO29762.1 - 5.6e-17 61.1 0.1 1.3e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 EGO29762.1 - 7.2e-06 25.8 0.5 7.2e-06 25.8 0.4 2.1 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 EGO29762.1 - 0.0039 16.4 0.5 0.0086 15.3 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding YppF PF14178.1 EGO29762.1 - 0.02 14.4 0.0 0.3 10.6 0.0 2.5 2 0 0 2 2 2 0 YppF-like protein NmrA PF05368.8 EGO29765.1 - 2.2e-46 158.0 0.0 2.7e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO29765.1 - 6.6e-18 65.3 0.0 8.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO29765.1 - 3.1e-08 32.6 0.0 5.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO29765.1 - 4.4e-06 26.2 0.0 9.6e-06 25.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGO29765.1 - 0.00072 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EGO29765.1 - 0.0051 16.7 0.2 0.0083 16.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EGO29765.1 - 0.0074 16.6 0.0 0.021 15.2 0.0 1.8 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EGO29765.1 - 0.0085 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EGO29765.1 - 0.092 12.4 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 KR domain CodY PF06018.9 EGO29767.1 - 0.052 12.8 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 CodY GAF-like domain LRR_6 PF13516.1 EGO29768.1 - 6.1e-08 31.9 1.1 0.053 13.6 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich repeat RasGEF_N_2 PF14663.1 EGO29768.1 - 0.045 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain LRR_4 PF12799.2 EGO29768.1 - 0.39 10.4 4.8 2 8.1 0.9 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_53 PF07745.8 EGO29769.1 - 3.6e-76 256.0 0.0 4.2e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 EGO29769.1 - 0.05 12.7 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4131 PF13567.1 EGO29770.1 - 0.007 15.7 0.4 0.049 13.0 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) MscS_TM PF12794.2 EGO29770.1 - 0.0083 14.7 1.0 0.012 14.2 0.7 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 DUF1469 PF07332.6 EGO29770.1 - 0.18 11.5 3.5 0.22 11.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) RseC_MucC PF04246.7 EGO29770.1 - 0.2 11.2 5.5 0.98 8.9 1.1 2.6 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Peptidase_C14 PF00656.17 EGO29771.1 - 3.5e-14 53.1 0.0 4.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EGO29772.1 - 1.1e-34 120.2 0.1 2.9e-34 118.8 0.0 1.7 1 1 0 1 1 1 1 Caspase domain LRR_6 PF13516.1 EGO29774.1 - 1.3e-05 24.7 5.3 0.13 12.4 0.1 5.0 5 1 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 EGO29774.1 - 0.0072 15.9 0.7 0.069 12.7 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO29774.1 - 0.067 13.2 0.7 15 6.0 0.2 4.2 2 1 0 2 2 2 0 Leucine Rich Repeat TENA_THI-4 PF03070.11 EGO29776.1 - 1e-10 41.7 0.1 2.1e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Ser_hydrolase PF06821.8 EGO29776.1 - 0.012 15.2 0.0 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase p450 PF00067.17 EGO29778.1 - 1.4e-77 261.2 0.0 2.2e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.1 EGO29781.1 - 3.4e-22 78.2 0.0 6.4e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO29781.1 - 1.3e-14 53.8 0.0 3.1e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO29781.1 - 1.5e-08 34.4 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO29781.1 - 3.8e-05 23.8 0.0 0.00065 19.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO29781.1 - 0.00013 22.4 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3277 PF11681.3 EGO29781.1 - 0.11 11.9 0.2 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) ubiquitin PF00240.18 EGO29782.1 - 2.5e-16 58.8 0.0 4.3e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGO29782.1 - 1.8e-07 30.7 0.0 3.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EGO29782.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ndufs5 PF10200.4 EGO29783.1 - 1.8e-05 24.6 0.7 2.4e-05 24.2 0.5 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 EGO29783.1 - 0.00062 19.4 2.1 0.00091 18.9 1.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 EGO29783.1 - 0.0091 16.0 3.0 0.017 15.2 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) Pet191_N PF10203.4 EGO29783.1 - 0.015 15.3 1.1 0.022 14.7 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EGO29783.1 - 0.12 12.2 5.4 2 8.4 4.2 2.1 1 1 1 2 2 2 0 CHCH domain DUF769 PF05590.6 EGO29783.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) PADR1 PF08063.7 EGO29783.1 - 0.17 11.2 2.6 9.8 5.6 0.0 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain COX6B PF02297.12 EGO29783.1 - 7.4 6.6 8.2 2.9 7.9 0.3 2.1 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb G-patch PF01585.18 EGO29784.1 - 1e-06 28.4 4.2 1e-06 28.4 2.9 1.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EGO29784.1 - 0.041 13.7 0.6 0.054 13.3 0.4 1.6 1 1 0 1 1 1 0 DExH-box splicing factor binding site HCaRG PF07258.9 EGO29784.1 - 0.063 12.8 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 HCaRG protein tRNA_anti-like PF12869.2 EGO29784.1 - 0.071 12.5 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like DUF3349 PF11829.3 EGO29785.1 - 0.037 14.4 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) UQ_con PF00179.21 EGO29786.1 - 7.6e-53 177.7 0.0 8.6e-53 177.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO29786.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO29786.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EGO29786.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Nup96 PF12110.3 EGO29788.1 - 5.1e-77 258.8 0.0 7.6e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 TEX19 PF15553.1 EGO29788.1 - 0.79 9.5 5.2 30 4.4 0.0 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 BUD22 PF09073.5 EGO29788.1 - 1.8 7.5 23.8 2.9 6.8 16.5 1.3 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.6 EGO29788.1 - 8.1 6.2 13.2 21 4.9 0.1 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal PALP PF00291.20 EGO29790.1 - 1.6e-55 188.5 0.0 3.2e-55 187.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lum_binding PF00677.12 EGO29792.1 - 1.5e-34 117.7 0.0 3.9e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain PALP PF00291.20 EGO29793.1 - 1e-54 185.8 0.2 2.4e-54 184.6 0.2 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 EGO29793.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF1399 PF07173.7 EGO29793.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) DUF2346 PF09803.4 EGO29794.1 - 1.2e-06 28.2 0.7 2.5e-06 27.2 0.5 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Pyridoxal_deC PF00282.14 EGO29795.1 - 6.3e-59 199.2 0.0 8.7e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGO29795.1 - 1.5e-06 27.1 0.0 2.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PIG-L PF02585.12 EGO29796.1 - 8e-17 61.9 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.5 EGO29797.1 - 0.00088 19.8 4.6 0.0017 18.8 3.2 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF3455 PF11937.3 EGO29798.1 - 3.3e-21 76.0 0.3 4.5e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Cyto_ox_2 PF02322.10 EGO29798.1 - 0.21 10.7 1.9 0.28 10.3 1.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II PIG-P PF08510.7 EGO29801.1 - 0.019 14.5 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 PIG-P Amdo_NSP PF12475.3 EGO29801.1 - 0.057 13.3 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Amdovirus non-structural protein DNA_primase_S PF01896.14 EGO29802.1 - 3.7e-52 176.0 0.1 5.4e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit zf-CCHC PF00098.18 EGO29803.1 - 0.0015 18.3 4.6 0.0028 17.5 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-PHD-like PF15446.1 EGO29803.1 - 0.066 12.5 2.4 0.13 11.5 1.6 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF3726 PF12525.3 EGO29803.1 - 0.13 12.0 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) RVP_2 PF08284.6 EGO29804.1 - 4.9e-06 26.5 0.0 5.4e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO29804.1 - 2.8e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO29804.1 - 0.00017 21.9 0.1 0.00022 21.6 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease ABC_tran PF00005.22 EGO29806.1 - 4.8e-48 162.9 0.0 1.1e-28 100.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO29806.1 - 6.8e-40 137.2 22.8 4.9e-21 75.3 6.2 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGO29806.1 - 5.5e-09 35.5 0.3 0.011 15.0 1.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGO29806.1 - 1.7e-07 30.8 0.0 0.0033 16.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EGO29806.1 - 4.8e-05 23.4 0.2 7.6 6.4 0.0 4.0 3 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EGO29806.1 - 0.00029 20.3 0.2 0.21 10.9 0.0 3.1 3 1 1 4 4 4 1 AAA-like domain AAA_29 PF13555.1 EGO29806.1 - 0.00036 19.9 1.1 0.11 12.0 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EGO29806.1 - 0.00063 18.7 0.1 0.65 8.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EGO29806.1 - 0.0009 19.2 0.2 0.93 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EGO29806.1 - 0.0011 19.2 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO29806.1 - 0.0012 19.0 0.3 0.79 9.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 EGO29806.1 - 0.027 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 KaiC PF06745.8 EGO29806.1 - 0.045 12.8 0.2 7.1 5.6 0.0 2.4 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.13 EGO29806.1 - 0.088 12.2 0.0 5 6.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 EGO29806.1 - 0.14 11.8 0.6 19 4.8 0.1 2.8 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 EGO29806.1 - 0.16 10.9 0.1 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EGO29806.1 - 0.16 12.2 0.1 15 5.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EGO29806.1 - 0.88 8.9 4.5 1.1 8.6 0.7 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Malic_M PF03949.10 EGO29808.1 - 1.4e-83 280.3 0.0 1.9e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGO29808.1 - 1.3e-65 220.3 0.0 2.8e-65 219.2 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain TFIIS_C PF01096.13 EGO29808.1 - 0.18 11.4 0.1 5.2 6.7 0.0 2.7 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) adh_short PF00106.20 EGO29809.1 - 1.8e-33 115.8 0.4 2.4e-33 115.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO29809.1 - 1.2e-25 90.6 0.0 1.6e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO29809.1 - 2.6e-18 66.3 0.2 3.7e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO29809.1 - 5.8e-05 23.1 0.2 0.0001 22.3 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO29809.1 - 6.7e-05 22.4 0.0 0.00014 21.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO29809.1 - 0.00034 20.3 0.1 0.00067 19.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.19 EGO29809.1 - 0.095 11.5 0.3 0.2 10.5 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NmrA PF05368.8 EGO29809.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_N PF08240.7 EGO29810.1 - 3.1e-28 97.7 0.5 6.9e-28 96.5 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO29810.1 - 2.2e-23 82.1 0.1 4.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO29810.1 - 4.3e-06 27.6 0.1 1.4e-05 25.9 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGO29810.1 - 0.0009 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EGO29810.1 - 0.0032 17.0 0.0 0.0078 15.8 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.7 EGO29810.1 - 0.0043 17.5 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO29810.1 - 0.0056 15.8 0.1 0.009 15.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 EGO29810.1 - 0.021 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.9 EGO29810.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.13 EGO29810.1 - 0.05 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EGO29810.1 - 0.081 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_4 PF01063.14 EGO29812.1 - 6.2e-26 91.2 0.0 9.3e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Dus PF01207.12 EGO29813.1 - 4.6e-58 196.4 0.0 5.9e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EGO29813.1 - 0.08 12.1 0.0 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein EMP24_GP25L PF01105.19 EGO29814.1 - 1.5e-39 135.6 0.1 2.8e-39 134.7 0.0 1.5 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD MR_MLE_C PF13378.1 EGO29815.1 - 8.5e-31 106.2 0.0 1.9e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EGO29815.1 - 1.3e-21 76.7 0.0 2.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EGO29815.1 - 3e-09 37.2 0.0 7.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain F-box-like PF12937.2 EGO29816.1 - 5.9e-05 22.7 0.5 0.00016 21.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like Glyco_hydro_61 PF03443.9 EGO29817.1 - 1.1e-61 208.4 0.1 1.6e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 EGO29817.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Wzt C-terminal domain Amino_oxidase PF01593.19 EGO29818.1 - 2e-13 50.2 0.0 2.5e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO29818.1 - 1.8e-09 37.4 0.0 1.8e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO29818.1 - 1.3e-06 27.5 0.0 0.00022 20.2 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Phage_capsid PF05065.8 EGO29818.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Phage capsid family Pyr_redox_3 PF13738.1 EGO29818.1 - 0.14 12.1 4.1 0.29 11.1 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO29818.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGO29818.1 - 0.54 10.6 3.0 12 6.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sperm_Ag_HE2 PF05324.8 EGO29820.1 - 0.011 15.6 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Sperm antigen HE2 DUF1156 PF06634.7 EGO29821.1 - 0.058 13.1 0.1 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) WWbp PF10349.4 EGO29824.1 - 0.25 12.2 2.7 0.33 11.8 1.9 1.1 1 0 0 1 1 1 0 WW-domain ligand protein Alpha_kinase PF02816.13 EGO29825.1 - 4.2e-08 33.0 0.0 7.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family DUF1880 PF08976.6 EGO29825.1 - 0.017 15.2 1.9 0.036 14.1 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1880) SPC25 PF06703.6 EGO29826.1 - 2.5e-38 131.2 0.0 3e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4231 PF14015.1 EGO29826.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) ERG2_Sigma1R PF04622.7 EGO29827.1 - 2.7e-82 275.2 0.2 3.3e-82 274.9 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein p450 PF00067.17 EGO29828.1 - 3.2e-70 236.9 0.0 3.9e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO29829.1 - 2e-65 221.1 0.0 2.7e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO29830.1 - 2.8e-17 62.4 0.0 3.1e-09 35.8 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 RNase_H2-Ydr279 PF09468.5 EGO29830.1 - 0.066 12.3 0.1 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) p450 PF00067.17 EGO29831.1 - 1.6e-63 214.8 0.0 2.5e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Histone PF00125.19 EGO29832.1 - 1.5e-26 92.2 0.0 1.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO29832.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO29833.1 - 1.9e-21 75.9 0.2 3.1e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO29833.1 - 1.4e-05 25.0 0.1 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGO29833.1 - 0.00023 21.4 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EGO29833.1 - 0.047 14.1 0.2 0.071 13.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 EGO29833.1 - 0.09 12.1 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein SOBP PF15279.1 EGO29833.1 - 0.11 12.8 2.9 0.12 12.7 2.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2282 PF10048.4 EGO29834.1 - 0.0024 17.7 1.3 0.0031 17.3 0.9 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2282) Suf PF05843.9 EGO29835.1 - 3.6 7.2 6.8 4.3 6.9 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 EGO29835.1 - 6.9 6.4 5.9 9.2 6.0 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 EGO29835.1 - 9.5 5.1 7.0 14 4.5 4.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Histone PF00125.19 EGO29836.1 - 1.2e-21 76.5 0.2 1.8e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO29836.1 - 6.8e-05 22.8 0.1 6.8e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGO29836.1 - 0.00029 21.0 0.0 0.00057 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EGO29836.1 - 0.042 14.3 0.6 0.058 13.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EGO29836.1 - 0.049 13.0 0.2 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain Med3 PF11593.3 EGO29836.1 - 1.2 8.2 6.4 1.2 8.3 4.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Histone PF00125.19 EGO29837.1 - 1.2e-26 92.6 0.1 1.5e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO29837.1 - 1.2e-08 34.9 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fungal_trans PF04082.13 EGO29838.1 - 2.9e-08 32.9 0.0 9.4e-08 31.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO29838.1 - 0.0029 17.4 7.6 0.0059 16.4 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 EGO29839.1 - 9.9e-07 28.2 0.3 2e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO29839.1 - 1.1e-05 25.0 0.7 2.2e-05 24.0 0.5 1.5 1 0 0 1 1 1 1 F-box-like GRAB PF10375.4 EGO29840.1 - 5.5e-07 28.9 0.9 1.3e-06 27.8 0.7 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain KLRAQ PF10205.4 EGO29840.1 - 0.0016 18.4 8.6 0.0016 18.4 6.0 3.9 1 1 3 4 4 4 1 Predicted coiled-coil domain-containing protein GRIP PF01465.15 EGO29840.1 - 0.059 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 GRIP domain PspA_IM30 PF04012.7 EGO29840.1 - 0.21 10.9 31.5 0.16 11.3 2.3 2.7 1 1 1 2 2 2 0 PspA/IM30 family LPP PF04728.8 EGO29840.1 - 0.53 10.1 3.7 0.86 9.4 0.5 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.7 EGO29840.1 - 5.6 6.7 8.7 2.2 8.1 2.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EGO29840.1 - 5.7 5.7 32.8 0.19 10.6 10.6 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IFT57 PF10498.4 EGO29840.1 - 7.5 5.1 24.9 0.045 12.4 6.8 2.4 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 DUF1664 PF07889.7 EGO29840.1 - 9.8 5.9 10.4 10 5.9 0.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) HECT_2 PF09814.4 EGO29841.1 - 1.2e-40 139.3 0.0 1.6e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 EGO29841.1 - 0.05 13.6 0.2 0.24 11.4 0.2 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.27 EGO29843.1 - 2.1e-18 65.4 7.1 3.4e-06 26.7 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 EGO29843.1 - 0.2 9.4 0.1 0.3 8.8 0.0 1.1 1 0 0 1 1 1 0 IKI3 family 2-oxoacid_dh PF00198.18 EGO29844.1 - 3.8e-81 271.7 0.1 5.3e-81 271.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGO29844.1 - 2.4e-19 68.7 2.4 4.7e-19 67.7 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EGO29844.1 - 0.0036 16.9 1.2 0.0086 15.7 0.3 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 EGO29844.1 - 0.019 14.1 3.4 0.052 12.7 0.7 2.0 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 EGO29844.1 - 0.027 14.1 0.3 0.064 12.9 0.2 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein Chitin_bind_3 PF03067.10 EGO29845.1 - 1.9e-13 51.0 0.5 2.4e-13 50.7 0.3 1.1 1 0 0 1 1 1 1 Chitin binding domain Homoserine_dh PF00742.14 EGO29848.1 - 1.9e-45 154.7 0.0 2.5e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGO29848.1 - 3.7e-16 59.5 0.0 1.1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGO29848.1 - 0.026 14.8 0.0 0.41 10.9 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RNA_pol_3_Rpc31 PF11705.3 EGO29850.1 - 1.2e-26 94.1 31.4 5.7e-26 91.8 21.8 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Rop-like PF05082.8 EGO29850.1 - 0.032 13.7 0.2 0.074 12.5 0.1 1.5 1 0 0 1 1 1 0 Rop-like PI3K_p85B PF02192.11 EGO29850.1 - 0.21 11.0 0.6 0.74 9.2 0.1 1.9 1 1 1 2 2 2 0 PI3-kinase family, p85-binding domain Sigma70_ner PF04546.8 EGO29850.1 - 7.4 6.1 7.6 9 5.8 3.9 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RRM_1 PF00076.17 EGO29851.1 - 8.7e-14 50.9 0.0 1.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO29851.1 - 1.2e-09 37.9 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGO29851.1 - 5.2e-06 26.8 0.3 5.2e-06 26.8 0.2 2.8 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EGO29851.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARS2 PF04959.8 EGO29851.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 PPTA PF01239.17 EGO29852.1 - 2.7e-44 146.7 15.8 1.8e-09 36.5 0.0 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.6 EGO29852.1 - 0.0095 15.4 0.5 0.02 14.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1549) PCMT PF01135.14 EGO29855.1 - 4.9e-73 245.1 0.1 5.8e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGO29855.1 - 9.6e-09 35.8 0.0 1.6e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO29855.1 - 8.5e-08 31.9 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO29855.1 - 3.4e-07 30.2 0.0 1.1e-06 28.7 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO29855.1 - 1.8e-06 27.7 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGO29855.1 - 3.5e-06 26.7 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO29855.1 - 0.00056 19.1 0.0 0.0033 16.5 0.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGO29855.1 - 0.0011 19.3 0.0 0.003 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGO29855.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EGO29855.1 - 0.0021 17.4 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGO29855.1 - 0.0059 15.7 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO29855.1 - 0.0076 16.5 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_1 PF00036.27 EGO29855.1 - 0.028 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2746 PF10874.3 EGO29855.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) EF-hand_5 PF13202.1 EGO29855.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 EF hand Mem_trans PF03547.13 EGO29856.1 - 1.2e-34 119.2 6.7 8.7e-33 113.1 0.1 2.2 2 0 0 2 2 2 2 Membrane transport protein DUF791 PF05631.9 EGO29857.1 - 2.7e-76 256.5 3.5 4.3e-76 255.9 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EGO29857.1 - 3.2e-16 59.0 27.1 3.2e-16 59.0 18.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_transf_20 PF00982.16 EGO29858.1 - 4.4e-141 470.6 0.0 4.6e-140 467.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGO29858.1 - 2.5e-68 229.5 0.0 4.5e-68 228.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DDA1 PF10172.4 EGO29859.1 - 0.074 12.8 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase Gpi1 PF05024.10 EGO29862.1 - 2.1e-48 164.5 8.0 2.1e-48 164.5 5.5 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DAO PF01266.19 EGO29863.1 - 3.3e-13 49.2 0.1 1.5e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO29863.1 - 0.056 13.4 0.3 1 9.4 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDP-g_GGTase PF06427.6 EGO29865.1 - 1.9e-54 184.1 0.0 3.1e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGO29865.1 - 4.5e-07 29.4 0.1 7.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_S30 PF01577.11 EGO29865.1 - 0.4 10.0 0.5 0.65 9.3 0.4 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease E1-E2_ATPase PF00122.15 EGO29866.1 - 6.2e-59 198.8 0.2 6.2e-59 198.8 0.2 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGO29866.1 - 1.5e-23 84.3 0.6 3.3e-23 83.2 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO29866.1 - 1.3e-14 54.8 0.2 3.6e-14 53.3 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO29866.1 - 1.5e-11 43.5 0.0 3.8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO29866.1 - 0.00013 21.6 0.0 0.00056 19.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO29866.1 - 0.13 12.1 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit zf-MYND PF01753.13 EGO29869.1 - 8.8e-07 28.6 4.8 1.5e-06 27.9 3.3 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EGO29869.1 - 0.05 12.8 0.8 0.088 12.1 0.6 1.3 1 0 0 1 1 1 0 Life-span regulatory factor Cnd3 PF12719.2 EGO29870.1 - 3.9e-81 272.3 0.8 2.1e-80 269.9 0.2 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGO29870.1 - 1.2e-08 35.1 8.3 2.3e-07 30.9 0.5 4.7 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.17 EGO29870.1 - 1.1e-05 25.1 3.0 6.8 7.0 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Ig_J_chain PF15097.1 EGO29870.1 - 0.025 14.1 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin J chain HEAT_EZ PF13513.1 EGO29870.1 - 0.026 15.0 6.1 0.077 13.5 0.2 4.4 5 0 0 5 5 5 0 HEAT-like repeat alpha-hel2 PF14456.1 EGO29873.1 - 0.24 10.1 0.9 0.26 10.0 0.6 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 HasA PF06438.7 EGO29874.1 - 0.064 12.6 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DUF4381 PF14316.1 EGO29876.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HNH_2 PF13391.1 EGO29879.1 - 0.0004 20.1 0.5 0.0018 17.9 0.3 2.1 1 1 0 1 1 1 1 HNH endonuclease Bt_P21 PF05560.6 EGO29880.1 - 0.098 12.0 0.0 0.098 12.0 0.0 1.0 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Pkinase PF00069.20 EGO29881.1 - 6.6e-72 241.7 0.0 1.6e-71 240.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO29881.1 - 2.5e-41 141.4 0.0 4.4e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EGO29881.1 - 1.7e-30 104.8 2.7 1.6e-19 69.6 0.2 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EGO29881.1 - 3.6e-08 32.7 0.0 2e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 EGO29881.1 - 0.0051 16.3 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) Thaumatin PF00314.12 EGO29882.1 - 1.9e-62 210.4 14.7 2.2e-62 210.2 10.2 1.0 1 0 0 1 1 1 1 Thaumatin family adh_short PF00106.20 EGO29883.1 - 9.6e-23 80.9 0.2 1.3e-22 80.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO29883.1 - 3.7e-07 29.9 0.1 5.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO29883.1 - 0.00016 21.4 0.1 0.00023 21.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO29883.1 - 0.00061 19.8 0.4 0.0032 17.4 0.3 2.2 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO29883.1 - 0.004 16.1 0.2 0.0063 15.4 0.2 1.5 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO29883.1 - 0.0042 16.5 0.2 0.0077 15.6 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4134 PF13572.1 EGO29884.1 - 0.37 10.9 3.0 0.84 9.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4134) BatA PF07584.6 EGO29884.1 - 1.2 9.3 4.9 17 5.6 0.1 3.1 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal RabGAP-TBC PF00566.13 EGO29887.1 - 2.6e-19 69.5 0.0 4.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2371 PF10177.4 EGO29887.1 - 0.19 11.5 2.3 0.38 10.6 1.6 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) FlgN PF05130.7 EGO29888.1 - 0.00075 19.7 5.6 0.00078 19.7 0.6 3.0 3 0 0 3 3 3 1 FlgN protein NPV_P10 PF05531.7 EGO29888.1 - 0.002 18.3 4.3 1.4 9.2 0.1 4.6 3 1 0 4 4 4 1 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 EGO29888.1 - 0.01 15.4 5.6 0.034 13.7 0.2 3.6 4 0 0 4 4 4 0 Prefoldin subunit DASH_Duo1 PF08651.5 EGO29888.1 - 0.022 14.3 1.4 11 5.6 0.0 3.8 4 0 0 4 4 4 0 DASH complex subunit Duo1 FliJ PF02050.11 EGO29888.1 - 0.028 14.4 0.9 3.2 7.8 0.3 3.0 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2730 PF10805.3 EGO29888.1 - 0.054 13.2 0.6 0.46 10.2 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 EGO29888.1 - 0.45 9.6 11.0 0.55 9.3 0.1 3.8 3 2 1 4 4 4 0 Reovirus sigma C capsid protein Syntaxin PF00804.20 EGO29888.1 - 0.45 10.7 5.8 4 7.6 0.3 3.8 4 0 0 4 4 4 0 Syntaxin FliD_C PF07195.7 EGO29888.1 - 0.46 9.7 4.9 7.9 5.6 0.4 3.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Transpep_BrtH PF14399.1 EGO29888.1 - 0.65 9.2 3.3 1.4 8.1 0.1 2.5 2 1 0 2 2 2 0 NlpC/p60-like transpeptidase DUF869 PF05911.6 EGO29888.1 - 0.71 8.0 2.9 4 5.5 0.5 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DivIC PF04977.10 EGO29888.1 - 1.4 8.4 4.8 28 4.2 0.3 3.4 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.3 EGO29888.1 - 3.7 7.4 6.9 4.3 7.2 0.7 3.4 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding DUF2961 PF11175.3 EGO29889.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Seryl_tRNA_N PF02403.17 EGO29890.1 - 0.0022 17.9 2.0 1.3 9.0 0.2 2.5 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF2580 PF10824.3 EGO29890.1 - 0.061 13.6 2.4 11 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) Med9 PF07544.8 EGO29890.1 - 0.062 13.0 0.2 7.3 6.4 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Flg_hook PF02120.11 EGO29890.1 - 0.081 12.6 0.7 0.18 11.4 0.5 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Laminin_II PF06009.7 EGO29890.1 - 0.2 11.4 3.9 0.26 11.0 0.1 2.5 3 0 0 3 3 3 0 Laminin Domain II Prefoldin_2 PF01920.15 EGO29890.1 - 0.26 11.0 1.7 5.7 6.7 0.1 3.1 3 1 0 3 3 3 0 Prefoldin subunit Prefoldin PF02996.12 EGO29890.1 - 0.5 10.0 3.1 2 8.0 0.1 2.9 3 1 0 3 3 3 0 Prefoldin subunit Bacillus_HBL PF05791.6 EGO29890.1 - 0.77 9.0 7.3 0.86 8.9 2.1 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EGO29890.1 - 0.84 9.2 3.5 1.6 8.3 1.4 2.2 2 1 0 2 2 2 0 IncA protein WXG100 PF06013.7 EGO29890.1 - 0.95 9.5 8.2 14 5.7 0.5 3.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF4200 PF13863.1 EGO29890.1 - 0.96 9.4 6.3 1.1 9.1 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) BCAS2 PF05700.6 EGO29890.1 - 1 8.8 4.8 0.37 10.2 0.2 2.0 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Aldedh PF00171.17 EGO29891.1 - 9.4e-83 278.0 0.0 1.2e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAM33 PF02330.11 EGO29894.1 - 2e-35 122.4 2.1 2.5e-35 122.1 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein LAB_N PF07578.6 EGO29896.1 - 0.028 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF91 PF01939.11 EGO29897.1 - 0.00036 19.7 0.0 0.00051 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF91 PDDEXK_4 PF14281.1 EGO29897.1 - 0.024 14.5 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily HSDR_N PF04313.9 EGO29897.1 - 0.031 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N_2 PF13588.1 EGO29897.1 - 0.095 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Glyco_hydro_cc PF11790.3 EGO29899.1 - 4.1e-35 121.3 0.0 7.8e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RasGAP PF00616.14 EGO29899.1 - 3.8e-33 114.8 0.0 6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Zn_clus PF00172.13 EGO29900.1 - 0.0032 17.3 13.1 0.0048 16.7 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.15 EGO29907.1 - 1.4e-70 237.9 0.0 1.9e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGO29907.1 - 0.00083 18.2 0.1 0.0034 16.2 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EGO29908.1 - 2.7e-57 194.2 0.0 3.7e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGO29908.1 - 0.046 12.5 0.9 0.078 11.7 0.1 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) CNH PF00780.17 EGO29910.1 - 1.7e-14 53.9 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain CBS PF00571.23 EGO29911.1 - 1.2e-17 63.3 0.5 0.00029 20.5 0.1 4.1 4 0 0 4 4 4 3 CBS domain Hid1 PF12722.2 EGO29911.1 - 0.099 10.3 0.0 0.16 9.6 0.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cys_Met_Meta_PP PF01053.15 EGO29912.1 - 1.7e-22 79.2 0.0 2.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGO29912.1 - 0.00024 20.2 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Amidase PF01425.16 EGO29913.1 - 6.3e-101 338.3 0.0 7.3e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Amidase PsiB PF06290.6 EGO29914.1 - 0.071 12.5 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Perilipin PF03036.11 EGO29915.1 - 1.3e-09 37.4 13.6 3.5e-08 32.7 0.1 3.4 1 1 0 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 EGO29915.1 - 0.003 17.0 6.6 0.021 14.3 4.4 2.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 EGO29915.1 - 0.0083 15.3 3.4 0.015 14.4 2.4 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF4631 PF15450.1 EGO29915.1 - 0.039 12.2 5.5 0.062 11.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Baculo_PEP_C PF04513.7 EGO29915.1 - 0.083 12.7 12.3 0.14 11.9 1.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERG2_Sigma1R PF04622.7 EGO29915.1 - 0.11 11.7 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein Sec8_exocyst PF04048.9 EGO29915.1 - 0.13 11.9 3.7 0.33 10.5 1.2 2.6 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Phasin PF05597.6 EGO29915.1 - 0.25 11.1 4.2 13 5.5 0.2 3.2 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SF-assemblin PF06705.6 EGO29915.1 - 0.27 10.3 5.4 0.31 10.1 0.9 2.4 2 1 0 2 2 2 0 SF-assemblin/beta giardin Prominin PF05478.6 EGO29915.1 - 0.32 8.4 9.0 0.46 7.9 6.3 1.2 1 0 0 1 1 1 0 Prominin EURL PF06937.6 EGO29915.1 - 0.52 9.6 5.6 0.17 11.2 1.3 1.9 1 1 2 3 3 3 0 EURL protein YtxH PF12732.2 EGO29915.1 - 1.8 8.9 4.8 7.8 6.9 0.4 3.1 2 1 1 3 3 3 0 YtxH-like protein Fib_alpha PF08702.5 EGO29915.1 - 4.2 7.4 12.8 1.6 8.8 1.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Vps39_2 PF10367.4 EGO29916.1 - 6.1e-11 42.4 0.1 5.6e-10 39.3 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EGO29916.1 - 4.5e-05 23.4 2.2 0.0036 17.2 0.0 3.0 2 1 1 3 3 3 2 Vacuolar sorting protein 39 domain 1 Cation_efflux PF01545.16 EGO29917.1 - 0.028 13.4 0.1 0.028 13.4 0.1 1.6 2 0 0 2 2 2 0 Cation efflux family MscS_TM PF12794.2 EGO29917.1 - 0.034 12.7 0.5 0.057 12.0 0.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RseC_MucC PF04246.7 EGO29917.1 - 0.18 11.3 1.7 2.8 7.5 0.5 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Glyco_hydro_92 PF07971.7 EGO29920.1 - 1.8e-130 435.9 0.7 2.6e-130 435.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MalM PF07148.7 EGO29920.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) NACHT PF05729.7 EGO29922.1 - 2.1e-09 37.2 0.0 4.2e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EGO29922.1 - 2.7e-06 27.2 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EGO29922.1 - 0.00016 21.8 0.0 0.00042 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO29922.1 - 0.002 18.1 0.0 0.0085 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO29922.1 - 0.0028 17.3 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 EGO29922.1 - 0.0096 14.8 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA PF00004.24 EGO29922.1 - 0.01 16.0 0.1 0.037 14.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGO29922.1 - 0.04 14.2 0.0 0.48 10.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO29922.1 - 0.1 12.5 0.3 2.2 8.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGO29922.1 - 0.1 11.4 0.0 0.24 10.2 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EGO29922.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PARP PF00644.15 EGO29924.1 - 2.1e-09 37.1 1.0 5.2e-08 32.5 0.1 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF466 PF04328.8 EGO29924.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF466) SNF2_N PF00176.18 EGO29925.1 - 2.4e-72 243.2 1.7 3.8e-72 242.6 1.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EGO29925.1 - 1.5e-48 164.4 19.8 1.5e-48 164.4 13.7 1.8 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 EGO29925.1 - 5.5e-13 48.5 0.0 1.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO29925.1 - 1e-07 31.0 0.2 3.2e-05 22.9 0.0 2.7 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EGO29925.1 - 3.3e-06 27.0 0.0 1.1e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MAPEG PF01124.13 EGO29926.1 - 5.3e-14 51.9 0.5 6.1e-14 51.7 0.3 1.1 1 0 0 1 1 1 1 MAPEG family Ion_trans_2 PF07885.11 EGO29926.1 - 0.0006 19.4 1.8 0.0086 15.7 0.1 2.2 2 0 0 2 2 2 1 Ion channel DUF4519 PF15012.1 EGO29927.1 - 0.0046 16.8 3.1 0.0084 16.0 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) Cnd3 PF12719.2 EGO29928.1 - 1.9e-75 253.6 6.3 2.2e-75 253.4 2.5 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EGO29928.1 - 0.0002 21.1 3.3 0.89 9.8 0.2 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGO29928.1 - 0.0046 16.8 0.7 0.43 10.4 0.2 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGO29928.1 - 0.0079 16.4 8.4 0.018 15.2 0.7 4.1 3 1 2 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EGO29928.1 - 0.033 14.6 4.9 0.56 10.7 0.8 4.2 3 1 1 4 4 4 0 HEAT-like repeat Sec23_trunk PF04811.10 EGO29930.1 - 8.1e-75 251.3 0.0 1.2e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGO29930.1 - 4.8e-35 119.0 0.3 1e-34 118.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGO29930.1 - 2.7e-30 104.7 0.2 5.7e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGO29930.1 - 1.1e-16 60.1 6.7 1.9e-16 59.3 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGO29930.1 - 1.9e-13 49.9 0.0 7e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat OPT PF03169.10 EGO29931.1 - 4.8e-136 454.7 49.7 5.5e-136 454.5 34.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EGO29932.1 - 8.8e-24 83.8 0.3 2.5e-23 82.3 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGO29932.1 - 3.9e-21 76.4 0.0 2.9e-20 73.6 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO29932.1 - 3.2e-20 73.1 0.0 6.1e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO29932.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO29932.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO29932.1 - 0.046 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus RNA_pol_N PF01194.12 EGO29933.1 - 1.8e-31 107.9 0.5 2.2e-31 107.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EGO29933.1 - 0.036 14.1 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PIP5K PF01504.13 EGO29934.1 - 9.8e-88 293.4 0.0 1.5e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RecO_N_2 PF13114.1 EGO29934.1 - 0.07 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 RecO N terminal Peptidase_C50 PF03568.12 EGO29936.1 - 3.6e-102 341.9 0.0 6.9e-102 340.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 EGO29936.1 - 1.3e-05 25.0 14.7 0.28 11.1 3.5 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO29936.1 - 0.00086 19.0 8.3 14 5.8 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGO29936.1 - 0.00091 19.0 3.2 3.7 7.5 0.6 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO29936.1 - 0.0022 17.6 4.9 5.8 6.6 0.0 4.7 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 EGO29936.1 - 3.6 7.6 7.6 15 5.6 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_21 PF13276.1 EGO29937.1 - 1.6e-05 24.7 0.8 0.013 15.4 0.1 2.2 2 0 0 2 2 2 2 HTH-like domain HTH_32 PF13565.1 EGO29937.1 - 0.00078 20.1 0.5 1.3 9.8 0.1 2.2 1 1 1 2 2 2 2 Homeodomain-like domain HTH_33 PF13592.1 EGO29937.1 - 0.043 13.3 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix COesterase PF00135.23 EGO29940.1 - 6.8e-83 279.1 0.5 8.5e-83 278.8 0.3 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO29940.1 - 8e-09 35.3 0.4 3.3e-08 33.3 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO29940.1 - 0.02 14.0 0.0 0.048 12.8 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO29940.1 - 0.032 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_4 PF13637.1 EGO29940.1 - 0.088 13.3 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) zf-CCHC_3 PF13917.1 EGO29945.1 - 2.3e-05 24.0 1.9 2.5e-05 23.9 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO29945.1 - 0.00022 20.9 6.4 0.00032 20.4 4.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4606 PF15379.1 EGO29945.1 - 0.68 10.0 3.4 1.2 9.2 2.3 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) Methyltransf_20 PF12147.3 EGO29947.1 - 0.14 10.9 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Putative methyltransferase zf-CCHC PF00098.18 EGO29950.1 - 8.2e-05 22.3 1.5 0.00017 21.3 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EGO29951.1 - 0.0002 21.2 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO29951.1 - 0.00044 20.0 0.0 0.00071 19.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO29951.1 - 0.00048 20.5 0.0 0.00058 20.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF4381 PF14316.1 EGO29953.1 - 0.049 13.7 0.2 0.054 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Retrotrans_gag PF03732.12 EGO29954.1 - 1.3e-07 31.6 1.4 2e-07 30.9 0.3 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein DUF1268 PF06896.6 EGO29955.1 - 0.12 12.6 1.4 0.33 11.2 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1268) OPT PF03169.10 EGO29956.1 - 1.5e-142 476.2 47.1 1.7e-142 476.0 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 EGO29956.1 - 1.7 8.4 7.0 0.58 9.9 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Methyltransf_31 PF13847.1 EGO29958.1 - 3.5e-27 94.8 0.0 6.2e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO29958.1 - 1.3e-18 67.2 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO29958.1 - 1.8e-14 54.2 0.0 5.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO29958.1 - 5.2e-14 52.4 0.0 3.7e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO29958.1 - 5e-12 45.8 0.2 1.6e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO29958.1 - 2.4e-11 43.9 0.0 5.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO29958.1 - 3.2e-11 42.8 0.0 6.8e-11 41.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Rhodanese PF00581.15 EGO29958.1 - 5.4e-11 42.8 0.2 2.8e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Methyltransf_23 PF13489.1 EGO29958.1 - 4.2e-10 39.5 0.0 1.4e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGO29958.1 - 4.4e-08 32.6 0.1 6.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO29958.1 - 1.7e-05 24.2 0.0 3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGO29958.1 - 6.6e-05 22.5 0.0 0.00016 21.2 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EGO29958.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 EGO29958.1 - 0.0065 14.8 0.0 0.011 14.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.7 EGO29958.1 - 0.0083 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) UPF0020 PF01170.13 EGO29958.1 - 0.025 14.1 0.1 0.066 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EGO29958.1 - 0.037 14.8 0.0 0.34 11.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.10 EGO29958.1 - 0.049 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EGO29958.1 - 0.053 12.5 0.0 0.82 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase DOT1 PF08123.8 EGO29958.1 - 0.07 12.4 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 HMG_box PF00505.14 EGO29960.1 - 5.4e-12 45.8 0.2 1.4e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO29960.1 - 0.001 19.3 0.2 0.0034 17.6 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain zf-MYND PF01753.13 EGO29965.1 - 1.2e-10 41.0 14.3 2.8e-10 39.9 9.9 1.7 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.1 EGO29965.1 - 0.061 13.2 0.1 0.27 11.2 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-Mss51 PF13824.1 EGO29965.1 - 3.4 7.6 10.4 7.2 6.5 7.2 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 HTH_33 PF13592.1 EGO29966.1 - 0.13 11.7 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix COesterase PF00135.23 EGO29967.1 - 2.6e-71 240.9 1.1 6.6e-71 239.6 0.2 1.8 2 0 0 2 2 2 1 Carboxylesterase family Ank_4 PF13637.1 EGO29967.1 - 0.11 13.0 0.0 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cation_ATPase_C PF00689.16 EGO29969.1 - 0.075 12.5 13.2 2 7.9 5.9 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus RVP PF00077.15 EGO29970.1 - 0.0044 16.9 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EGO29972.1 - 1.6e-06 28.0 0.6 3.9e-06 26.8 0.3 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein Dynein_light PF01221.13 EGO29972.1 - 0.1 12.6 0.4 0.22 11.5 0.2 1.7 2 0 0 2 2 2 0 Dynein light chain type 1 zf-C2H2_4 PF13894.1 EGO29974.1 - 0.29 11.5 5.8 0.11 12.8 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TRAP-gamma PF07074.7 EGO29976.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.2 1 1 2 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) HhH-GPD PF00730.20 EGO29978.1 - 2.8e-12 46.8 0.0 7.3e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGO29978.1 - 0.024 14.3 0.0 0.068 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TIM-br_sig_trns PF09370.5 EGO29978.1 - 0.041 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 TIM-barrel signal transduction protein Ish1 PF10281.4 EGO29978.1 - 0.053 13.6 0.0 6.9 6.8 0.1 3.2 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein HMG_box PF00505.14 EGO29982.1 - 1.4e-09 38.0 8.9 3.5e-08 33.5 6.1 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO29982.1 - 4e-08 33.5 1.8 9.7e-08 32.2 1.2 1.6 1 0 0 1 1 1 1 HMG-box domain DUF2672 PF10878.3 EGO29982.1 - 0.12 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Aldo_ket_red PF00248.16 EGO29983.1 - 1.1e-50 172.1 0.0 1.3e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Corona_M PF01635.13 EGO29984.1 - 0.052 12.4 1.1 0.063 12.2 0.8 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein AA_permease_2 PF13520.1 EGO29985.1 - 1.1e-40 139.4 13.3 1.1e-40 139.4 9.2 1.3 1 1 0 1 1 1 1 Amino acid permease Inhibitor_I78 PF11720.3 EGO29985.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I78 family WD40 PF00400.27 EGO29986.1 - 3e-21 74.4 12.8 6.1e-06 25.9 0.8 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_N PF14781.1 EGO29986.1 - 0.077 12.6 0.0 1.9 8.1 0.0 3.0 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Peptidase_C14 PF00656.17 EGO29987.1 - 5.3e-06 26.2 0.0 0.016 14.9 0.0 3.1 2 1 1 3 3 3 3 Caspase domain adh_short PF00106.20 EGO29988.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO29988.1 - 2.9e-05 23.8 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EGO29988.1 - 0.093 12.8 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UPF0220 PF05255.6 EGO29989.1 - 2.1e-50 170.1 0.0 2.7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ABC2_membrane_4 PF12730.2 EGO29989.1 - 0.039 13.1 1.3 0.11 11.6 0.4 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Peptidase_M13_N PF05649.8 EGO29990.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 Thaumatin PF00314.12 EGO29991.1 - 9.6e-14 51.3 11.0 1.2e-13 51.0 7.6 1.2 1 0 0 1 1 1 1 Thaumatin family rve PF00665.21 EGO29992.1 - 7e-05 22.9 0.1 0.00023 21.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO29992.1 - 0.0027 17.5 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 rve PF00665.21 EGO29994.1 - 7e-05 22.9 0.1 0.00023 21.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain ATG11 PF10377.4 EGO29994.1 - 0.0027 17.5 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 Thaumatin PF00314.12 EGO29996.1 - 4.8e-14 52.3 10.6 6e-14 52.0 7.4 1.2 1 0 0 1 1 1 1 Thaumatin family Costars PF14705.1 EGO29997.1 - 7e-15 54.7 0.1 9.7e-15 54.3 0.1 1.3 1 1 0 1 1 1 1 Costars RelB PF04221.7 EGO29997.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 RelB antitoxin Sigma70_r1_1 PF03979.9 EGO29997.1 - 0.073 13.0 0.2 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 tRNA-synt_1d PF00750.14 EGO30001.1 - 3.9e-80 269.3 1.2 5.2e-80 268.9 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGO30001.1 - 4.5e-18 65.3 0.0 8.5e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Syndecan PF01034.15 EGO30002.1 - 0.0068 16.0 0.5 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Syndecan domain DUF1191 PF06697.7 EGO30002.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EGO30002.1 - 0.084 13.2 0.1 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_UL45 PF05473.7 EGO30002.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 UL45 protein DUF1517 PF07466.6 EGO30002.1 - 9 5.1 10.0 0.12 11.3 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) SKG6 PF08693.5 EGO30003.1 - 0.013 14.7 1.3 0.028 13.7 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EGO30003.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.3 EGO30003.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Syndecan PF01034.15 EGO30003.1 - 0.027 14.0 0.4 0.061 12.9 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain IncA PF04156.9 EGO30003.1 - 0.12 12.0 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 IncA protein MAP65_ASE1 PF03999.7 EGO30005.1 - 0.0087 14.7 0.6 0.0087 14.7 0.4 2.1 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Mto2_bdg PF12808.2 EGO30005.1 - 0.039 14.0 4.4 0.11 12.6 3.1 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HMG_box PF00505.14 EGO30007.1 - 2.6e-12 46.8 0.1 4.8e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO30007.1 - 0.00049 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain RVP_2 PF08284.6 EGO30008.1 - 5e-09 36.2 0.0 5.5e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO30008.1 - 4e-06 26.5 0.0 5.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO30008.1 - 6.3e-06 26.6 0.0 7.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2E PF12382.3 EGO30008.1 - 0.016 15.0 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon peptidase zf-CCHC PF00098.18 EGO30009.1 - 4.3e-08 32.6 1.1 6.4e-08 32.1 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO30009.1 - 0.014 15.0 0.4 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO30009.1 - 0.11 12.1 0.5 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle IBR PF01485.16 EGO30011.1 - 5.1e-10 39.0 34.7 1.3e-06 28.1 5.5 3.4 3 0 0 3 3 3 2 IBR domain DUF2835 PF11197.3 EGO30011.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Phage_CRI PF05144.9 EGO30012.1 - 0.045 12.8 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI LRR_4 PF12799.2 EGO30014.1 - 3.8 7.2 12.1 3 7.5 0.1 5.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_S13_N PF08069.7 EGO30015.1 - 1.5e-29 101.5 0.5 3.2e-29 100.5 0.2 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGO30015.1 - 5.8e-23 80.4 0.1 7.7e-23 80.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S6e PF01092.14 EGO30016.1 - 2e-59 198.7 0.1 4e-59 197.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e HJURP_C PF12347.3 EGO30016.1 - 0.019 14.5 0.5 0.039 13.5 0.4 1.5 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat DEAD PF00270.24 EGO30017.1 - 4.7e-18 65.2 0.0 1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO30017.1 - 2.2e-08 33.8 0.0 6.2e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO30017.1 - 4.8e-07 29.7 0.0 3.6e-06 26.9 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Aldo_ket_red PF00248.16 EGO30018.1 - 3.8e-50 170.3 0.0 4.5e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF706 PF05153.10 EGO30019.1 - 9.3e-128 424.8 2.1 1.1e-127 424.5 1.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EGO30019.1 - 0.0035 17.3 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 HD domain HAD PF12710.2 EGO30020.1 - 5.3e-16 59.3 0.0 7.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO30020.1 - 3.1e-08 34.0 0.0 1.6e-06 28.4 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGO30020.1 - 3e-06 26.5 0.0 7.7e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 EGO30020.1 - 5.3e-06 26.9 0.0 0.00057 20.3 0.0 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EGO30020.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) SpoU_sub_bind PF08032.7 EGO30020.1 - 0.015 15.4 0.0 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Lactamase_B_2 PF12706.2 EGO30020.1 - 0.057 12.9 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LNS2 PF08235.8 EGO30020.1 - 0.073 12.6 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Transket_pyr PF02779.19 EGO30021.1 - 1.3e-59 200.6 0.0 1.9e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGO30021.1 - 7.2e-43 146.4 0.0 1.2e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component SMC_N PF02463.14 EGO30022.1 - 2.8e-29 101.9 8.8 3.1e-29 101.7 5.7 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 EGO30022.1 - 4.1e-07 29.5 8.6 7.2e-05 22.1 1.1 2.9 3 0 0 3 3 3 2 Reovirus sigma C capsid protein WEMBL PF05701.6 EGO30022.1 - 2e-06 26.5 34.7 0.00032 19.3 0.4 3.2 3 0 0 3 3 3 2 Weak chloroplast movement under blue light AAA_21 PF13304.1 EGO30022.1 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Filament PF00038.16 EGO30022.1 - 0.00041 19.9 35.7 0.003 17.0 12.2 3.4 3 0 0 3 3 3 2 Intermediate filament protein SbcCD_C PF13558.1 EGO30022.1 - 0.00045 20.0 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit MscS_porin PF12795.2 EGO30022.1 - 0.00074 18.8 30.1 0.054 12.8 0.0 3.4 3 1 0 3 3 3 1 Mechanosensitive ion channel porin domain ADIP PF11559.3 EGO30022.1 - 0.0041 17.0 37.3 0.4 10.5 12.5 3.6 3 0 0 3 3 3 3 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EGO30022.1 - 0.0049 15.3 28.5 0.61 8.4 10.5 3.3 2 1 0 3 3 3 3 AAA domain FlaC_arch PF05377.6 EGO30022.1 - 0.012 15.5 4.6 0.012 15.5 3.2 4.9 5 2 2 7 7 4 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 EGO30022.1 - 0.012 15.3 25.9 0.054 13.2 5.3 3.8 3 1 0 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EGO30022.1 - 0.012 15.3 9.5 0.86 9.4 1.2 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 EGO30022.1 - 0.022 14.6 44.4 2 8.3 0.5 4.5 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec8_exocyst PF04048.9 EGO30022.1 - 0.025 14.2 19.7 0.14 11.8 6.5 3.6 3 2 0 3 3 3 0 Sec8 exocyst complex component specific domain IncA PF04156.9 EGO30022.1 - 0.03 13.9 44.3 0.58 9.7 16.4 3.3 2 1 1 3 3 3 0 IncA protein DUF3584 PF12128.3 EGO30022.1 - 0.034 11.4 38.4 0.091 10.0 26.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Cep57_MT_bd PF06657.8 EGO30022.1 - 0.037 13.9 15.6 0.84 9.6 0.5 3.7 2 2 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.6 EGO30022.1 - 0.051 12.2 37.5 0.54 8.8 4.3 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EGO30022.1 - 0.057 13.6 14.9 4.9 7.4 2.3 5.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 EGO30022.1 - 0.12 10.5 31.8 0.12 10.5 9.9 3.6 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA ATG16 PF08614.6 EGO30022.1 - 0.16 11.8 39.7 0.049 13.4 1.5 4.0 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EGO30022.1 - 0.22 11.3 43.6 0.49 10.2 17.5 3.7 3 0 0 3 3 3 0 Tropomyosin like THOC7 PF05615.8 EGO30022.1 - 0.23 11.7 29.8 0.37 11.0 0.7 4.3 3 2 0 3 3 3 0 Tho complex subunit 7 DUF4201 PF13870.1 EGO30022.1 - 0.26 10.7 33.3 0.67 9.3 0.8 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) DUF1664 PF07889.7 EGO30022.1 - 0.35 10.6 21.2 3.2 7.5 0.2 5.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EGO30022.1 - 0.4 10.1 24.7 4 6.9 9.5 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF745) DUF948 PF06103.6 EGO30022.1 - 0.48 10.3 10.0 2.4 8.0 2.1 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMP_2 PF06791.8 EGO30022.1 - 0.6 9.6 4.3 0.36 10.4 0.8 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein Atg14 PF10186.4 EGO30022.1 - 0.7 8.7 39.4 0.1 11.5 1.3 4.2 3 2 1 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 EGO30022.1 - 0.72 9.0 39.0 0.99 8.5 1.3 3.8 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.7 EGO30022.1 - 0.72 9.1 35.9 22 4.3 17.8 4.3 2 1 1 3 3 3 0 PspA/IM30 family DASH_Duo1 PF08651.5 EGO30022.1 - 1 8.9 10.3 0.84 9.2 0.5 4.2 3 2 2 5 5 5 0 DASH complex subunit Duo1 DUF972 PF06156.8 EGO30022.1 - 1.3 9.4 25.9 0.85 9.9 0.5 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF972) FliJ PF02050.11 EGO30022.1 - 1.5 8.8 32.8 3.5 7.7 8.8 4.4 2 1 2 4 4 4 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 EGO30022.1 - 3.2 7.4 40.3 5.8 6.6 1.6 4.3 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 EGO30022.1 - 3.5 7.6 28.7 2 8.4 2.8 4.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF2730 PF10805.3 EGO30022.1 - 4 7.2 12.2 24 4.7 3.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF869 PF05911.6 EGO30022.1 - 4.8 5.2 37.5 20 3.2 3.8 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) V_ATPase_I PF01496.14 EGO30022.1 - 5.9 4.6 29.6 1.4 6.6 0.3 3.1 2 1 0 3 3 3 0 V-type ATPase 116kDa subunit family FliD_N PF02465.13 EGO30022.1 - 6.3 7.2 12.0 0.43 10.9 2.4 3.2 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus COG2 PF06148.6 EGO30022.1 - 7.9 6.3 22.6 1.9 8.3 3.2 4.4 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.5 EGO30022.1 - 9.1 6.3 29.9 1.5 8.9 5.9 4.7 1 1 3 5 5 5 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.5 EGO30022.1 - 9.6 6.0 6.3 27 4.6 0.0 3.8 3 1 0 3 3 3 0 DASH complex subunit Dam1 Methyltransf_25 PF13649.1 EGO30023.1 - 1.4e-07 31.7 0.0 3.1e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO30023.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGO30024.1 - 8.3e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO30024.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GlutR_dimer PF00745.15 EGO30025.1 - 0.052 13.4 0.0 1.1 9.1 0.0 2.9 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DEAD PF00270.24 EGO30026.1 - 3e-09 36.6 0.0 4.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO30026.1 - 0.0029 17.4 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 EGO30026.1 - 0.033 12.7 0.0 0.041 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Methyltransf_25 PF13649.1 EGO30027.1 - 8.1e-07 29.3 0.0 3e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO30027.1 - 0.0082 15.8 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PLAC8 PF04749.12 EGO30028.1 - 0.11 13.1 0.7 0.12 12.9 0.5 1.2 1 0 0 1 1 1 0 PLAC8 family F-box-like PF12937.2 EGO30029.1 - 4.4e-08 32.7 1.0 4.4e-08 32.7 0.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EGO30029.1 - 0.084 12.6 0.6 0.82 9.4 0.0 3.0 4 0 0 4 4 4 0 Leucine rich repeat Peptidase_S9 PF00326.16 EGO30030.1 - 7.5e-33 113.5 0.1 1.3e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO30030.1 - 8.1e-08 32.1 0.0 2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO30030.1 - 0.00054 19.9 0.2 0.0034 17.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EGO30030.1 - 0.001 18.6 4.7 0.27 10.9 0.1 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.8 EGO30030.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO30030.1 - 0.014 14.8 0.2 0.13 11.6 0.0 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PQQ_3 PF13570.1 EGO30030.1 - 0.028 14.6 1.6 0.14 12.4 0.8 2.5 2 0 0 2 2 2 0 PQQ-like domain AXE1 PF05448.7 EGO30030.1 - 0.13 10.7 0.9 0.33 9.4 0.1 2.0 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) adh_short PF00106.20 EGO30031.1 - 5.3e-08 32.9 0.0 9.9e-08 32.0 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short PF00106.20 EGO30033.1 - 2e-19 70.1 0.1 2.5e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO30033.1 - 2.3e-08 33.9 0.0 2.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EGO30033.1 - 0.11 11.9 0.0 1.2 8.7 0.0 2.4 1 1 1 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EGO30033.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding DcpS_C PF11969.3 EGO30039.1 - 0.097 12.9 0.0 0.25 11.5 0.0 1.6 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.2 EGO30040.1 - 0.00057 19.5 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 F-box-like NMD3 PF04981.8 EGO30041.1 - 1.8e-73 246.5 0.2 2.4e-73 246.1 0.2 1.1 1 0 0 1 1 1 1 NMD3 family Rpr2 PF04032.11 EGO30041.1 - 0.042 13.7 1.9 4.5 7.2 0.3 2.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1289 PF06945.8 EGO30041.1 - 0.1 12.1 0.1 16 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) TT_ORF2 PF02957.10 EGO30041.1 - 0.1 13.2 3.3 2.3 8.9 0.0 2.5 2 0 0 2 2 2 0 TT viral ORF2 DZR PF12773.2 EGO30041.1 - 0.12 12.1 7.8 2.1 8.2 5.6 2.6 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.7 EGO30041.1 - 0.22 11.3 2.2 0.4 10.5 0.5 2.2 2 0 0 2 2 2 0 NinF protein GFA PF04828.9 EGO30041.1 - 0.27 11.1 3.5 6 6.8 0.1 3.2 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.1 EGO30041.1 - 1.5 8.5 5.5 0.35 10.5 0.3 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.1 EGO30042.1 - 0.0092 15.7 1.3 7.7 6.3 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat HEAT PF02985.17 EGO30043.1 - 1.4e-13 49.6 1.2 4.4e-05 23.2 0.0 4.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 EGO30043.1 - 6.9e-06 26.2 0.1 0.00094 19.4 0.1 2.8 1 1 0 1 1 1 1 HEAT repeats Cnd1 PF12717.2 EGO30043.1 - 3.7e-05 23.6 0.6 0.0026 17.6 0.1 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGO30043.1 - 0.00012 20.5 0.0 0.00012 20.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.1 EGO30043.1 - 0.0016 18.8 0.2 0.17 12.4 0.0 3.2 3 0 0 3 3 3 1 HEAT-like repeat Synapsin_N PF10581.4 EGO30043.1 - 0.0058 16.4 1.7 14 5.5 0.0 3.4 3 0 0 3 3 3 1 Synapsin N-terminal HEAT PF02985.17 EGO30044.1 - 1.1e-06 28.1 0.1 1.3 9.2 0.0 3.1 3 0 0 3 3 3 3 HEAT repeat DUF2235 PF09994.4 EGO30045.1 - 8e-61 205.8 0.0 9.9e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) F-box-like PF12937.2 EGO30046.1 - 0.016 14.8 0.0 0.06 13.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like O-FucT PF10250.4 EGO30049.1 - 4.8e-05 22.6 0.0 0.00013 21.2 0.0 1.6 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HMG_box PF00505.14 EGO30051.1 - 1.9e-11 44.0 0.4 3.3e-11 43.2 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO30051.1 - 0.00034 20.9 0.1 0.00069 19.9 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain RseA_C PF03873.8 EGO30057.1 - 0.057 13.3 0.3 0.16 11.8 0.2 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Pyocin_S PF06958.7 EGO30057.1 - 0.36 11.1 4.8 0.081 13.2 0.7 1.9 1 1 1 2 2 2 0 S-type Pyocin LRR_6 PF13516.1 EGO30059.1 - 0.019 15.0 2.3 2.4 8.4 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.2 EGO30059.1 - 0.049 13.3 1.4 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 F-box-like DNA_pol_A PF00476.15 EGO30061.1 - 3.8e-93 312.1 0.0 6.4e-93 311.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A RFC1 PF08519.7 EGO30061.1 - 0.04 13.6 0.5 0.38 10.4 0.2 2.5 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Cellulase PF00150.13 EGO30067.1 - 2.1e-13 50.1 0.0 3.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGO30067.1 - 0.022 15.1 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-binding cellulase-like Cu2_monooxygen PF01082.15 EGO30069.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain FAD_binding_4 PF01565.18 EGO30071.1 - 5e-21 74.6 2.3 7.9e-21 73.9 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO30071.1 - 1.6e-05 24.7 0.0 4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 EGO30072.1 - 2.1e-38 131.9 51.0 2.6e-38 131.6 33.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO30072.1 - 4.3e-23 81.3 13.5 6.1e-23 80.8 9.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO30072.1 - 1.7e-14 53.2 10.6 1.7e-14 53.2 7.3 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter DUF3094 PF11293.3 EGO30072.1 - 2 7.9 5.1 1.3 8.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) CMAS PF02353.15 EGO30073.1 - 2.4e-52 177.7 0.4 3.6e-52 177.1 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EGO30073.1 - 1.5e-09 38.4 0.1 1.9e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO30073.1 - 7.7e-09 35.4 0.1 2e-08 34.1 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO30073.1 - 3.9e-05 23.6 0.1 6.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO30073.1 - 0.00023 21.5 0.0 0.00067 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO30073.1 - 0.00092 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGO30073.1 - 0.0069 15.9 0.0 0.034 13.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain UPF0020 PF01170.13 EGO30073.1 - 0.041 13.4 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 EGO30073.1 - 0.053 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RC-P840_PscD PF10657.4 EGO30074.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD FMN_red PF03358.10 EGO30076.1 - 8.4e-09 35.1 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EGO30076.1 - 8.2e-05 22.6 0.0 0.00025 21.0 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EGO30076.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EGO30077.1 - 2.3e-07 30.8 0.0 3.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EGO30077.1 - 5e-07 29.3 0.0 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGO30077.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Bacteriocin_IIc PF10439.4 EGO30077.1 - 2.3 8.3 6.8 1 9.4 1.3 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Hydrophobin PF01185.13 EGO30078.1 - 1.4e-21 76.7 6.3 1.7e-21 76.4 4.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EGO30079.1 - 1e-22 80.3 6.5 1.4e-22 79.9 4.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin VKOR PF07884.9 EGO30079.1 - 0.14 11.9 5.0 0.19 11.5 3.5 1.3 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF4418 PF14387.1 EGO30079.1 - 0.2 11.4 4.2 0.3 10.8 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) PAS_9 PF13426.1 EGO30080.1 - 3.7e-25 88.2 0.0 4.1e-15 56.0 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EGO30080.1 - 9.5e-12 44.7 0.0 2.4e-06 27.2 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.6 EGO30080.1 - 3.2e-10 39.9 0.0 1.7e-05 24.7 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.5 EGO30080.1 - 1.8e-07 31.1 0.0 0.00049 20.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EGO30080.1 - 1e-06 28.6 0.0 4.8e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 PAS domain Pkinase PF00069.20 EGO30081.1 - 4.4e-50 170.2 0.0 6.1e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30081.1 - 2.9e-23 82.2 0.0 4e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGO30081.1 - 0.00029 19.7 0.2 0.00061 18.7 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EGO30081.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyocin_S PF06958.7 EGO30081.1 - 1.8 8.9 5.6 6 7.2 0.1 2.8 2 0 0 2 2 2 0 S-type Pyocin Ribosomal_L44 PF00935.14 EGO30082.1 - 6.2e-36 122.2 11.1 9.8e-36 121.6 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 AAA_12 PF13087.1 EGO30083.1 - 7.3e-44 149.5 0.0 1.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO30083.1 - 1e-30 107.0 4.2 1.5e-28 100.0 2.9 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EGO30083.1 - 0.011 15.9 0.0 0.037 14.1 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain RdRP PF05183.7 EGO30084.1 - 1.3e-110 370.7 0.0 2e-110 370.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sec63 PF02889.11 EGO30085.1 - 2.6e-191 634.6 0.0 2.8e-97 325.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGO30085.1 - 3.2e-53 179.6 0.3 1.4e-29 102.7 0.2 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGO30085.1 - 2.8e-17 63.1 0.1 1.5e-10 41.2 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO30085.1 - 4.2e-13 48.9 0.0 1.7e-08 34.1 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGO30085.1 - 1.5e-06 28.3 0.1 0.026 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EGO30085.1 - 0.0004 19.6 0.0 0.029 13.5 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EGO30085.1 - 0.0025 16.7 0.0 0.16 10.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EGO30085.1 - 0.11 12.5 0.0 6.3 6.8 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EGO30085.1 - 0.11 12.8 3.3 2.1 8.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 EGO30086.1 - 7.2e-16 57.3 5.7 0.00081 19.1 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 EGO30086.1 - 2.2e-08 33.9 0.0 2.2e-08 33.9 0.0 3.0 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 EGO30086.1 - 0.12 11.9 1.0 11 5.6 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.20 EGO30087.1 - 6.8e-42 143.4 0.0 1.1e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30087.1 - 1.9e-41 141.8 0.0 2.7e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO30087.1 - 0.00027 20.0 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO30087.1 - 0.007 16.1 1.2 0.033 13.9 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF164 PF02591.10 EGO30087.1 - 0.1 12.4 2.1 6.8 6.6 0.5 2.9 2 0 0 2 2 2 0 Putative zinc ribbon domain PRP21_like_P PF12230.3 EGO30087.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Sgf11 PF08209.6 EGO30087.1 - 2.6 7.4 8.6 3 7.2 0.2 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pkinase PF00069.20 EGO30088.1 - 1.5e-37 129.1 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30088.1 - 1.1e-36 126.2 0.0 1.5e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO30088.1 - 0.0099 15.6 0.2 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S26e PF01283.14 EGO30089.1 - 2.3e-51 172.8 9.2 2.7e-51 172.6 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EGO30089.1 - 0.029 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Transp_Tc5_C PF04236.10 EGO30089.1 - 0.24 11.6 2.5 0.65 10.2 0.2 2.2 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C2H2 PF00096.21 EGO30090.1 - 7.5e-12 44.8 49.0 0.034 14.4 0.1 10.6 10 1 1 11 11 11 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGO30090.1 - 2.8e-10 40.0 27.9 0.18 11.9 0.0 8.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.1 EGO30090.1 - 6.7e-06 25.7 14.1 6.7e-06 25.7 9.8 4.8 5 1 1 6 6 5 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO30090.1 - 3e-05 23.5 13.4 3e-05 23.5 9.3 4.9 5 2 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO30090.1 - 3.2e-05 23.6 12.9 3.2e-05 23.6 9.0 4.6 3 1 1 4 4 4 1 Ring finger domain zf-met PF12874.2 EGO30090.1 - 4.5e-05 23.4 44.2 0.037 14.2 0.0 10.6 11 1 0 11 11 11 4 Zinc-finger of C2H2 type zf-C3HC4_2 PF13923.1 EGO30090.1 - 4.9e-05 23.2 13.6 4.9e-05 23.2 9.4 5.9 2 1 3 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 EGO30090.1 - 5e-05 23.3 69.1 0.003 17.7 0.1 11.7 11 3 1 12 12 11 5 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 EGO30090.1 - 0.00046 19.7 11.7 0.00046 19.7 8.1 5.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.1 EGO30090.1 - 0.00071 19.3 34.1 0.12 12.3 0.1 7.4 5 1 1 6 6 6 3 C2H2-type zinc finger zf-RING_6 PF14835.1 EGO30090.1 - 0.43 10.4 10.7 0.14 11.9 4.8 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein rve PF00665.21 EGO30091.1 - 2.3e-24 85.7 0.0 5.1e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EGO30091.1 - 2.5e-24 85.8 0.1 9.6e-24 83.9 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EGO30091.1 - 3.5e-14 52.2 0.2 7.9e-14 51.0 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 EGO30091.1 - 2.5e-05 24.2 0.0 6.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO30091.1 - 0.0033 17.8 0.0 0.0082 16.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO30091.1 - 0.018 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UCH PF00443.24 EGO30092.1 - 2.7e-44 151.3 0.0 4.7e-44 150.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO30092.1 - 7.8e-10 38.6 0.4 4.1e-05 23.1 0.0 3.9 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_1 PF00232.13 EGO30093.1 - 8.8e-156 518.6 3.5 1.1e-155 518.2 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 adh_short PF00106.20 EGO30094.1 - 5.6e-10 39.3 0.1 8.7e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGO30094.1 - 5.6e-05 23.2 0.0 8.8e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EGO30094.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO30094.1 - 0.00058 19.5 0.1 0.0019 17.9 0.0 1.8 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EGO30094.1 - 0.0097 15.3 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EGO30095.1 - 8.8e-39 132.4 0.0 1.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO30095.1 - 3.1e-26 91.3 0.0 3.5e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EGO30095.1 - 1.3e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGO30095.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EGO30095.1 - 0.046 14.2 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pribosyltran PF00156.22 EGO30096.1 - 9e-15 54.5 0.7 1.5e-14 53.7 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DER1 PF04511.10 EGO30097.1 - 7.9e-32 110.3 0.6 8.9e-32 110.1 0.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF2046 PF09755.4 EGO30098.1 - 1e-11 44.3 5.6 1e-11 44.3 3.9 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) HSP20 PF00011.16 EGO30098.1 - 3.5e-11 42.8 0.0 8.3e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pkinase PF00069.20 EGO30100.1 - 9.2e-08 31.5 0.2 3.3e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30100.1 - 0.0048 16.0 0.1 0.024 13.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGO30100.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sulfolobus_pRN PF05584.6 EGO30100.1 - 0.035 14.0 0.1 0.76 9.7 0.0 2.5 3 0 0 3 3 3 0 Sulfolobus plasmid regulatory protein APH PF01636.18 EGO30100.1 - 0.071 12.8 0.0 0.49 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Helicase_C PF00271.26 EGO30101.1 - 3.5e-10 39.6 0.0 7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO30102.1 - 1.9e-06 26.9 0.0 3.1e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain FliT PF05400.8 EGO30102.1 - 0.094 13.1 0.1 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FliT SNF2_N PF00176.18 EGO30103.1 - 4.5e-13 48.6 1.4 6.6e-13 48.1 0.2 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 EGO30103.1 - 0.0002 20.9 0.0 0.0026 17.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO30103.1 - 0.022 14.5 0.0 0.074 12.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGO30104.1 - 1.7e-10 40.1 0.2 6.5e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 EGO30104.1 - 0.0046 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HhH-GPD PF00730.20 EGO30107.1 - 3e-06 27.4 0.0 3.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TIP49 PF06068.8 EGO30108.1 - 1.3e-172 574.0 0.0 1.5e-172 573.7 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGO30108.1 - 7.6e-10 39.1 0.1 2.2e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO30108.1 - 4.8e-09 35.6 0.2 6.2e-07 28.7 0.0 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO30108.1 - 3.7e-07 30.3 0.0 5.1e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EGO30108.1 - 1.1e-05 25.1 0.1 0.0063 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO30108.1 - 2.1e-05 24.7 0.2 0.06 13.4 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO30108.1 - 0.0006 19.5 0.0 0.0026 17.4 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGO30108.1 - 0.0011 18.9 0.1 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGO30108.1 - 0.0048 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO30108.1 - 0.0082 16.0 0.0 0.08 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO30108.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EGO30108.1 - 0.029 14.2 0.0 7 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO30108.1 - 0.033 15.0 0.0 0.077 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EGO30108.1 - 0.038 13.1 0.1 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGO30108.1 - 0.053 12.6 0.4 0.1 11.6 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 EGO30108.1 - 0.08 12.4 0.0 5.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 EGO30108.1 - 0.14 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EGO30108.1 - 0.31 10.2 2.2 0.52 9.5 0.0 2.4 4 0 0 4 4 4 0 PhoH-like protein CBFD_NFYB_HMF PF00808.18 EGO30110.1 - 1.4e-21 76.3 1.1 1.8e-21 75.9 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO30110.1 - 1.4e-09 37.9 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EGO30110.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 EGO30110.1 - 0.025 14.4 0.4 0.04 13.8 0.2 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) DnaJ PF00226.26 EGO30111.1 - 4.3e-21 74.4 0.4 4.3e-21 74.4 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EGO30111.1 - 1.9e-20 72.3 4.4 1.6e-12 46.8 0.0 5.4 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 EGO30111.1 - 5.3e-17 60.6 4.6 0.00024 20.5 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO30111.1 - 3.4e-15 54.6 8.3 0.0012 18.5 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO30111.1 - 5.4e-15 55.5 5.6 2.2e-05 24.9 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO30111.1 - 2.9e-14 53.1 3.5 0.00027 21.2 0.0 6.5 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO30111.1 - 3.6e-12 45.7 2.8 0.42 11.3 0.3 6.6 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGO30111.1 - 9.3e-12 44.6 2.0 0.0028 17.4 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO30111.1 - 2.1e-10 39.6 0.0 0.019 14.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO30111.1 - 1.2e-09 37.2 1.6 0.59 10.0 0.0 5.9 5 2 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO30111.1 - 6.7e-09 35.7 7.4 9.4e-06 25.6 0.3 3.7 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGO30111.1 - 6.5e-08 32.1 0.7 0.013 15.6 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO30111.1 - 2.2e-07 30.8 3.6 1.2 9.7 0.1 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO30111.1 - 1e-06 28.5 5.5 0.23 11.4 0.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.12 EGO30111.1 - 0.00023 21.4 4.4 0.11 12.7 0.0 3.7 3 1 0 3 3 3 1 Bacterial transcriptional activator domain DUF3808 PF10300.4 EGO30111.1 - 0.036 12.6 0.0 0.095 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_4 PF07721.9 EGO30111.1 - 0.53 10.8 6.8 16 6.3 1.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 EGO30112.1 - 4e-45 153.1 0.0 6.2e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO30112.1 - 6.4e-19 67.7 0.0 8.1e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO30112.1 - 6.3e-06 26.1 0.0 1.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EGO30112.1 - 0.09 13.2 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Peroxidase_2 PF01328.12 EGO30113.1 - 5.7e-22 77.7 0.0 1.1e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 CDC45 PF02724.9 EGO30114.1 - 0.5 8.3 10.0 0.73 7.7 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EGO30114.1 - 1.6 6.9 11.6 2.4 6.3 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 EGO30114.1 - 8.4 5.8 15.7 15 5.0 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ifi-6-16 PF06140.8 EGO30115.1 - 0.044 13.5 0.2 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Interferon-induced 6-16 family UPRTase PF14681.1 EGO30116.1 - 1.8e-77 259.1 0.0 2.1e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGO30116.1 - 7.2e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.1 EGO30116.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Pkinase PF00069.20 EGO30119.1 - 5.4e-07 29.0 0.0 9.5e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30119.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3809 PF12723.2 EGO30119.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) EMG1 PF03587.9 EGO30121.1 - 3.9e-75 251.5 0.0 5e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CRAL_TRIO PF00650.15 EGO30122.1 - 1.1e-34 119.2 0.0 1.4e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO30122.1 - 2e-13 50.2 0.2 5.9e-13 48.7 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGO30122.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain p450 PF00067.17 EGO30123.1 - 6.2e-70 235.9 0.0 8.5e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO30124.1 - 3.8e-68 230.0 0.3 2e-46 158.5 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Actin PF00022.14 EGO30125.1 - 1.4e-155 517.6 0.0 1.6e-155 517.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGO30125.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RPE65 PF03055.10 EGO30127.1 - 3.3e-122 408.5 0.0 3.7e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein VWA_2 PF13519.1 EGO30131.1 - 1.2e-12 48.3 0.0 2.1e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EGO30131.1 - 2.7e-11 42.0 18.7 0.00021 20.5 0.5 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 EGO30131.1 - 3.7e-08 33.2 0.2 7.6e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Ssl1-like SCO1-SenC PF02630.9 EGO30132.1 - 5.2e-53 179.2 0.0 7.4e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EGO30132.1 - 0.0028 17.3 0.0 0.009 15.6 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGO30132.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like DUF4051 PF13260.1 EGO30132.1 - 0.29 10.4 2.3 30 4.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4051) CGI-121 PF08617.5 EGO30133.1 - 9.1e-38 129.4 0.3 1e-37 129.2 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.15 EGO30134.1 - 8.4e-48 160.3 0.2 5.7e-25 86.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EGO30134.1 - 9.1e-19 67.9 0.0 5.6e-10 39.3 0.0 4.1 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGO30134.1 - 5.3e-09 36.0 0.0 0.00018 21.5 0.0 3.1 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGO30134.1 - 7e-09 35.8 3.3 2.1e-06 27.9 0.3 3.6 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGO30134.1 - 0.002 18.1 0.4 0.32 11.0 0.1 2.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EGO30134.1 - 0.0093 15.7 0.0 0.66 9.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain GCM PF03615.10 EGO30134.1 - 0.02 14.5 0.4 0.34 10.5 0.1 2.7 3 0 0 3 3 3 0 GCM motif protein GcpE PF04551.9 EGO30134.1 - 0.021 13.6 0.0 0.39 9.4 0.0 2.1 2 0 0 2 2 2 0 GcpE protein Thioredoxin_9 PF14595.1 EGO30134.1 - 0.033 13.7 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 EGO30134.1 - 0.033 14.2 1.1 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin Colicin_Pyocin PF01320.13 EGO30134.1 - 0.068 13.0 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein PPR_2 PF13041.1 EGO30135.1 - 5.9e-41 138.2 0.4 1.9e-08 34.1 0.0 13.0 12 2 3 15 15 15 10 PPR repeat family PPR PF01535.15 EGO30135.1 - 7.7e-35 116.4 6.6 0.00069 19.4 0.0 13.3 16 0 0 16 16 16 6 PPR repeat PPR_1 PF12854.2 EGO30135.1 - 1.6e-28 97.8 2.1 3e-07 29.7 0.0 10.5 10 0 0 10 10 10 5 PPR repeat PPR_3 PF13812.1 EGO30135.1 - 6.4e-28 94.6 16.1 0.00011 22.1 0.0 14.1 17 0 0 17 17 17 6 Pentatricopeptide repeat domain TPR_14 PF13428.1 EGO30135.1 - 1.9e-09 37.3 3.4 0.97 10.2 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO30135.1 - 1.3e-05 25.4 0.7 5.9 7.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO30135.1 - 0.0044 17.6 6.0 1.4 9.6 0.1 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat RPM2 PF08579.6 EGO30135.1 - 0.0055 16.8 1.5 0.49 10.5 0.0 3.5 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) DUF4381 PF14316.1 EGO30136.1 - 0.051 13.6 0.2 0.057 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4348 PF14254.1 EGO30139.1 - 0.041 12.9 0.2 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) XK-related PF09815.4 EGO30141.1 - 0.073 12.0 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 XK-related protein DUF2065 PF09838.4 EGO30142.1 - 0.0019 17.8 1.5 0.045 13.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2065) DUF3522 PF12036.3 EGO30142.1 - 0.038 13.7 0.4 0.05 13.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) DUF308 PF03729.8 EGO30142.1 - 1.2 9.1 8.2 2.7 8.0 0.6 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Ifi-6-16 PF06140.8 EGO30142.1 - 1.3 8.8 15.6 2.1 8.2 10.8 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family Bacteriocin_IIc PF10439.4 EGO30142.1 - 4.1 7.6 6.9 0.66 10.1 1.7 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Bac_rhamnosid PF05592.6 EGO30143.1 - 1.6e-26 92.6 2.4 6.9e-16 57.5 0.7 3.1 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EGO30143.1 - 4.8e-06 25.4 0.2 7.2e-06 24.9 0.2 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 EGO30143.1 - 3e-05 22.9 4.6 4.6e-05 22.3 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 F_bP_aldolase PF01116.15 EGO30144.1 - 3.3e-99 331.6 0.0 3.7e-99 331.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 EGO30144.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Flavin_Reduct PF01613.13 EGO30147.1 - 3.6e-19 69.1 0.0 5.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Npa1 PF11707.3 EGO30148.1 - 2.5e-67 227.2 0.0 2.5e-67 227.2 0.0 3.7 5 0 0 5 5 5 1 Ribosome 60S biogenesis N-terminal Abhydrolase_6 PF12697.2 EGO30149.1 - 6.5e-16 58.9 0.7 8.2e-16 58.5 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO30149.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AIRC PF00731.15 EGO30150.1 - 4.1e-63 211.1 0.9 4.1e-63 211.1 0.6 1.5 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 EGO30150.1 - 2.9e-10 39.7 0.0 4.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Rsa3 PF14615.1 EGO30151.1 - 9.3e-10 37.6 0.1 1.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Cyclin_N PF00134.18 EGO30152.1 - 2.9e-11 43.0 0.5 6.6e-10 38.6 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EGO30152.1 - 0.0013 18.4 0.2 0.0028 17.4 0.1 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Ldh_1_C PF02866.13 EGO30153.1 - 3.1e-44 150.7 0.0 4.9e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGO30153.1 - 1.4e-38 131.9 0.1 2e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGO30153.1 - 0.0016 18.7 0.7 0.0076 16.5 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGO30153.1 - 0.0023 16.7 0.0 0.0032 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO30153.1 - 0.0027 17.7 0.7 0.0049 16.8 0.5 1.4 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EGO30153.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WGG PF10273.4 EGO30154.1 - 3.6e-27 94.2 0.0 5.2e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Clp1 PF06807.9 EGO30155.1 - 1.5e-10 41.2 0.0 3.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGO30155.1 - 4.7e-08 32.8 0.0 8.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGO30155.1 - 0.0021 17.5 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EGO30155.1 - 0.004 17.0 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO30155.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EGO30155.1 - 0.073 13.2 0.1 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EGO30155.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF2910 PF11139.3 EGO30156.1 - 0.35 9.9 2.2 0.57 9.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Hemerythrin PF01814.18 EGO30157.1 - 7.1e-12 45.6 1.8 8.6e-12 45.3 0.8 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Asp PF00026.18 EGO30161.1 - 6.3e-14 51.9 0.0 8.1e-13 48.2 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic aspartyl protease Cpn60_TCP1 PF00118.19 EGO30162.1 - 3e-134 448.2 13.0 3.5e-134 448.0 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PMT PF02366.13 EGO30163.1 - 5.8e-77 258.3 17.0 5.8e-77 258.3 11.8 2.2 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGO30163.1 - 2.7e-43 147.7 0.4 4.2e-43 147.1 0.3 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EGO30163.1 - 5.1e-06 26.4 15.7 5.1e-06 26.4 10.9 3.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.7 EGO30163.1 - 0.77 10.0 5.5 6.1 7.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) PPR_2 PF13041.1 EGO30165.1 - 1.3e-10 41.1 0.1 1.9e-05 24.5 0.0 4.4 4 1 1 5 5 5 3 PPR repeat family PPR_1 PF12854.2 EGO30165.1 - 0.00013 21.3 1.6 0.058 12.8 0.0 3.6 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 EGO30165.1 - 0.00015 21.7 0.2 0.67 10.3 0.0 4.5 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EGO30165.1 - 0.011 15.6 0.1 4.7 7.4 0.0 3.5 4 0 0 4 4 4 0 PPR repeat ECSIT PF06239.6 EGO30165.1 - 0.047 12.5 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Thymidylat_synt PF00303.14 EGO30166.1 - 2e-110 368.0 0.0 2.3e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HD PF01966.17 EGO30167.1 - 3.7e-11 43.0 1.2 1e-10 41.6 0.1 2.2 3 0 0 3 3 3 1 HD domain Phg_2220_C PF09524.5 EGO30167.1 - 0.086 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) TruB-C_2 PF09157.6 EGO30167.1 - 0.16 11.8 0.0 0.52 10.2 0.0 1.8 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal p450 PF00067.17 EGO30169.1 - 6.9e-57 192.9 0.0 5e-35 120.9 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 zf-CCHC PF00098.18 EGO30170.1 - 1.9e-06 27.5 3.8 2.4e-06 27.1 1.4 2.0 2 0 0 2 2 2 1 Zinc knuckle CpXC PF14353.1 EGO30170.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 CpXC protein Tet_JBP PF12851.2 EGO30171.1 - 3.8e-05 23.0 0.0 9.5e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily TAP42 PF04177.7 EGO30171.1 - 0.046 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 TAP42-like family TnpB_IS66 PF05717.8 EGO30171.1 - 0.051 13.0 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 IS66 Orf2 like protein WD40 PF00400.27 EGO30173.1 - 0.0023 17.7 0.2 11 6.0 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 EGO30174.1 - 1.8e-21 75.1 2.0 8.2e-10 38.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 EGO30174.1 - 0.0014 18.4 1.0 0.01 15.6 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO30174.1 - 0.0033 17.4 1.2 0.0089 16.0 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO30174.1 - 0.048 13.3 3.3 0.13 11.8 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGO30174.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.1 EGO30174.1 - 0.097 12.4 3.9 0.4 10.4 2.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain EF-hand_4 PF12763.2 EGO30175.1 - 9.8e-14 50.9 0.0 9.1e-09 34.9 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand ATP-synt_DE PF00401.15 EGO30177.1 - 0.061 13.2 1.6 0.12 12.2 1.1 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Phage_holin_T PF11031.3 EGO30179.1 - 0.13 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T holin JAB PF01398.16 EGO30181.1 - 1.1e-10 41.2 0.1 2.4e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DNA_pol_A_exo1 PF01612.15 EGO30182.1 - 0.03 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease DUF4479 PF14794.1 EGO30182.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Thioredoxin_2 PF13098.1 EGO30185.1 - 0.067 13.3 0.1 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain SH3_1 PF00018.23 EGO30186.1 - 8e-12 44.3 0.1 1.4e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO30186.1 - 2.8e-09 36.3 0.0 5.5e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGO30186.1 - 4.2e-09 35.8 0.0 6.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain IATP PF04568.7 EGO30188.1 - 0.34 10.9 2.5 5.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP WAC_Acf1_DNA_bd PF10537.4 EGO30189.1 - 7.2e-33 112.8 0.4 7.2e-33 112.8 0.3 2.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EGO30189.1 - 6.8e-15 54.5 1.5 2e-14 53.0 0.3 2.3 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.1 EGO30189.1 - 5.3e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EGO30189.1 - 0.00011 21.9 0.2 0.00037 20.3 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EGO30189.1 - 0.00093 18.9 0.4 0.0022 17.7 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 HPP PF04982.8 EGO30190.1 - 0.086 12.6 0.8 0.11 12.3 0.5 1.5 1 1 0 1 1 1 0 HPP family GPI2 PF06432.6 EGO30193.1 - 0.069 12.4 0.5 0.085 12.1 0.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4048 PF13257.1 EGO30194.1 - 0.01 15.5 0.1 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) Ribosomal_S24e PF01282.14 EGO30196.1 - 1e-33 114.9 0.0 1.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e ERAP1_C PF11838.3 EGO30200.1 - 0.035 13.3 0.0 0.09 12.0 0.0 1.5 2 0 0 2 2 2 0 ERAP1-like C-terminal domain CRAL_TRIO PF00650.15 EGO30200.1 - 0.093 12.2 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 CRAL/TRIO domain Myosin_head PF00063.16 EGO30202.1 - 5e-224 745.3 3.0 8.1e-224 744.6 2.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGO30202.1 - 1.4e-39 135.4 0.0 2.2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Myosin tail SH3_2 PF07653.12 EGO30202.1 - 7.8e-10 38.0 0.0 1.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGO30202.1 - 9.1e-09 34.7 0.2 2e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO30202.1 - 1.8e-08 33.6 1.1 3.6e-08 32.6 0.8 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 EGO30202.1 - 8.4e-05 22.6 0.4 0.00024 21.2 0.3 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EGO30202.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO30202.1 - 0.018 15.8 0.0 0.084 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EGO30202.1 - 0.019 14.2 1.4 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EGO30202.1 - 0.02 14.0 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EGO30202.1 - 0.026 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EGO30202.1 - 0.037 13.6 0.0 0.099 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EGO30202.1 - 0.066 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RVT_2 PF07727.9 EGO30204.1 - 3.2e-06 26.2 0.0 4.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aconitase_2_N PF06434.8 EGO30204.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus DDE_3 PF13358.1 EGO30206.1 - 1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease SNAPc_SNAP43 PF09808.4 EGO30208.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 zf-CCHC PF00098.18 EGO30209.1 - 1.9e-08 33.8 4.7 3.7e-08 32.9 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30209.1 - 7.6e-05 22.7 4.4 7.6e-05 22.7 3.0 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO30209.1 - 0.028 14.1 2.3 0.057 13.1 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Herpes_UL55 PF04537.7 EGO30209.1 - 0.054 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein Ribosomal_L13e PF01294.13 EGO30210.1 - 1.4e-59 200.5 4.4 2.2e-59 199.9 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Whirly PF08536.6 EGO30213.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Whirly transcription factor zf-met PF12874.2 EGO30214.1 - 0.017 15.3 0.1 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO30214.1 - 0.021 14.9 0.4 0.057 13.5 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO30214.1 - 0.053 13.6 0.2 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Retrotrans_gag PF03732.12 EGO30217.1 - 1.9e-07 31.0 0.1 1.9e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein NYD-SP28_assoc PF14775.1 EGO30217.1 - 0.033 13.9 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain Apc4 PF12896.2 EGO30219.1 - 4.3e-27 94.8 0.1 7.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF773 PF05600.7 EGO30220.1 - 0.0079 15.0 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF773) Retrotrans_gag PF03732.12 EGO30222.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein PINIT PF14324.1 EGO30223.1 - 4.3e-35 120.8 0.2 7.6e-35 120.0 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EGO30223.1 - 6.7e-17 60.7 7.1 1.2e-16 59.8 5.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGO30223.1 - 6.3e-06 25.6 0.9 1.4e-05 24.4 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EGO30223.1 - 0.0051 16.2 0.6 0.03 13.8 0.0 2.5 3 0 0 3 3 3 1 SAP domain Hrs_helical PF12210.3 EGO30225.1 - 0.049 13.8 0.4 0.75 10.0 0.0 2.4 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Sialidase PF02973.11 EGO30225.1 - 0.083 11.8 0.1 3.1 6.7 0.0 2.1 1 1 1 2 2 2 0 Sialidase, N-terminal domain DUF1192 PF06698.6 EGO30227.1 - 0.13 12.0 2.0 0.16 11.8 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Sec1 PF00995.18 EGO30229.1 - 1.1e-138 463.3 0.0 1.4e-138 463.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Phage_Mu_Gam PF07352.7 EGO30229.1 - 0.02 14.4 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein GCD14 PF08704.5 EGO30230.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit LIN37 PF15306.1 EGO30232.1 - 0.2 11.6 3.0 0.23 11.4 2.1 1.0 1 0 0 1 1 1 0 LIN37 DUF2464 PF10240.4 EGO30232.1 - 0.25 10.6 1.8 0.26 10.5 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Hep_59 PF07052.6 EGO30232.1 - 0.95 9.8 6.0 0.14 12.5 1.5 1.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DUF2589 PF11655.3 EGO30232.1 - 1.3 9.1 4.6 1.4 9.0 3.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2589) XAP5 PF04921.9 EGO30232.1 - 2.1 7.8 6.0 2.2 7.7 4.2 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator gag_pre-integrs PF13976.1 EGO30233.1 - 9.5e-10 37.9 0.5 1.2e-09 37.6 0.3 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Esterase PF00756.15 EGO30235.1 - 2.9e-40 138.2 0.0 3.4e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGO30235.1 - 8.1e-06 25.6 0.1 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO30235.1 - 0.0047 16.1 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EGO30235.1 - 0.022 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Pkinase PF00069.20 EGO30236.1 - 8e-58 195.6 0.1 9.7e-58 195.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30236.1 - 6.6e-20 71.2 0.0 9.8e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO30236.1 - 1.7e-07 31.2 0.1 5.6e-06 26.2 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO30236.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGO30236.1 - 0.024 13.6 0.1 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBN2_2 PF14227.1 EGO30239.1 - 3.1e-07 29.9 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO30239.1 - 3.3e-05 23.6 0.0 5.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 EGO30239.1 - 0.034 13.8 2.0 0.084 12.5 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4402 PF14352.1 EGO30240.1 - 0.075 13.5 0.1 0.076 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Retrotrans_gag PF03732.12 EGO30243.1 - 0.00024 21.0 0.1 0.00055 19.9 0.0 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein MRP-L28 PF09812.4 EGO30244.1 - 0.21 11.4 13.8 0.27 11.0 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 V_ATPase_I PF01496.14 EGO30244.1 - 1.1 7.0 9.7 1.3 6.8 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 EGO30244.1 - 9.2 4.4 14.9 11 4.2 10.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Exonuc_VII_L PF02601.10 EGO30244.1 - 9.8 5.2 12.0 12 4.9 8.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bromodomain PF00439.20 EGO30245.1 - 4.2e-36 122.7 0.0 5.6e-18 64.6 0.1 2.6 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.27 EGO30245.1 - 2.4e-23 81.1 13.5 1.1e-07 31.5 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF1664 PF07889.7 EGO30245.1 - 0.051 13.3 0.6 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.12 EGO30250.1 - 2e-07 30.9 3.2 5.1e-07 29.6 1.8 2.0 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO30251.1 - 5.5e-05 22.8 1.7 9.6e-05 22.0 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO30251.1 - 0.0006 19.6 6.4 0.001 18.8 4.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Fibrinogen_aC PF12160.3 EGO30253.1 - 0.11 11.9 0.9 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain EutB PF06751.6 EGO30254.1 - 0.1 10.9 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Drc1-Sld2 PF11719.3 EGO30255.1 - 3.3e-13 49.5 3.0 3.3e-13 49.5 2.1 2.6 2 1 1 3 3 3 1 DNA replication and checkpoint protein MAGE_N PF12440.3 EGO30255.1 - 0.35 11.1 6.5 2.1 8.6 1.9 3.0 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal PCI PF01399.22 EGO30257.1 - 5.3e-16 58.8 0.0 3.8e-15 56.0 0.0 2.4 2 1 0 2 2 2 1 PCI domain SID-1_RNA_chan PF13965.1 EGO30258.1 - 0.5 8.4 1.7 0.6 8.2 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SPARC_Ca_bdg PF10591.4 EGO30258.1 - 0.74 9.8 8.8 1.4 8.9 6.1 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Med15 PF09606.5 EGO30258.1 - 2.8 6.0 23.0 3.2 5.8 15.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal APG6 PF04111.7 EGO30258.1 - 4 6.4 14.7 4.7 6.1 10.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2361 PF10153.4 EGO30258.1 - 6.6 6.9 12.9 9.3 6.4 9.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) PTPlike_phytase PF14566.1 EGO30258.1 - 8.6 6.3 8.8 4.5 7.3 3.3 1.9 1 1 1 2 2 2 0 Inositol hexakisphosphate Asp_protease_2 PF13650.1 EGO30264.1 - 3.4e-05 24.2 0.0 4.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO30264.1 - 0.00024 21.0 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO30264.1 - 0.00027 20.6 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Siva PF05458.7 EGO30264.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Cd27 binding protein (Siva) Metallophos PF00149.23 EGO30265.1 - 1.8e-42 145.0 0.1 2.2e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 EGO30267.1 - 1.7e-29 102.5 0.0 6.7e-29 100.5 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO30267.1 - 2.4e-05 24.1 7.2 4.8e-05 23.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S19 PF06756.6 EGO30267.1 - 0.037 13.8 0.5 0.14 12.0 0.4 1.9 1 0 0 1 1 1 0 Chorion protein S19 C-terminal ATG16 PF08614.6 EGO30268.1 - 0.084 12.6 1.3 0.16 11.7 0.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3684 PF12449.3 EGO30271.1 - 0.02 12.4 0.2 0.025 12.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Dsl1_N PF11988.3 EGO30271.1 - 0.11 11.3 1.5 0.6 8.9 0.0 2.0 1 1 1 2 2 2 0 Retrograde transport protein Dsl1 N terminal DUF4413 PF14372.1 EGO30272.1 - 0.0086 16.0 5.4 0.095 12.6 3.6 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4413) Complex1_30kDa PF00329.14 EGO30274.1 - 1.3e-36 124.9 0.0 1.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PHD PF00628.24 EGO30275.1 - 0.0021 17.7 0.6 0.0055 16.3 0.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-FPG_IleRS PF06827.9 EGO30275.1 - 0.011 15.3 0.7 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS UPF0547 PF10571.4 EGO30275.1 - 0.31 10.7 5.6 2.9 7.6 0.3 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 EGO30275.1 - 4.8 7.2 10.5 3.2 7.8 0.1 3.3 3 1 0 3 3 3 0 zinc-finger QH-AmDH_gamma PF08992.6 EGO30277.1 - 0.04 13.6 1.1 0.22 11.2 0.8 2.1 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase, gamma subunit Xlink PF00193.12 EGO30277.1 - 0.12 12.4 1.9 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Extracellular link domain HTH_23 PF13384.1 EGO30278.1 - 2.3e-06 27.0 0.0 3.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGO30278.1 - 0.068 13.1 0.1 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGO30278.1 - 0.081 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Ribosomal_L15e PF00827.12 EGO30279.1 - 9e-91 302.5 11.4 1e-90 302.4 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF1014 PF06244.7 EGO30280.1 - 0.83 9.8 5.3 20 5.4 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1014) Ribosomal_L13 PF00572.13 EGO30281.1 - 7e-28 97.2 0.3 1.1e-27 96.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 DEAD PF00270.24 EGO30282.1 - 5.4e-10 39.0 0.0 1.3e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase PilP PF04351.8 EGO30283.1 - 0.048 13.5 1.2 1.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Pilus assembly protein, PilP Tom37_C PF11801.3 EGO30283.1 - 0.57 10.0 3.6 2.9 7.7 0.8 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain BUD22 PF09073.5 EGO30283.1 - 6.3 5.7 19.6 0.72 8.8 8.7 1.9 2 0 0 2 2 2 0 BUD22 DCP2 PF05026.8 EGO30286.1 - 1.9e-35 120.5 2.0 4.1e-35 119.5 1.4 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EGO30286.1 - 1.8e-13 50.3 0.0 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF2063 PF09836.4 EGO30289.1 - 0.062 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) Pex16 PF08610.5 EGO30290.1 - 3.6e-57 193.8 1.5 4.6e-57 193.5 1.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) gag_pre-integrs PF13976.1 EGO30292.1 - 3e-09 36.3 0.1 4.7e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 EGO30292.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Integrase core domain DUF3112 PF11309.3 EGO30294.1 - 0.022 14.5 0.8 0.025 14.3 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Glyco_transf_21 PF13506.1 EGO30296.1 - 6e-22 77.7 2.6 6.9e-17 61.2 0.1 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EGO30296.1 - 2.9e-19 69.7 0.0 3.9e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO30296.1 - 0.00079 19.1 0.1 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF1091 PF06477.8 EGO30305.1 - 0.0061 16.9 0.3 1.8 9.0 0.0 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF1091) Yippee-Mis18 PF03226.9 EGO30307.1 - 7e-23 80.4 0.1 8.2e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EGO30307.1 - 0.024 14.5 0.6 0.69 9.9 0.6 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2039 PF10217.4 EGO30307.1 - 0.073 13.0 0.2 2.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 EGO30307.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon Endonuclease_7 PF02945.10 EGO30307.1 - 0.12 12.1 1.0 0.34 10.6 0.7 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII Urocanase PF01175.13 EGO30308.1 - 0.16 9.9 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Urocanase RasGAP PF00616.14 EGO30312.1 - 0.043 13.4 0.3 0.13 11.9 0.0 1.8 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase GTP_EFTU PF00009.22 EGO30314.1 - 2.9e-59 199.6 0.7 4.5e-59 199.0 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO30314.1 - 2.1e-27 95.1 0.1 5.8e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO30314.1 - 3.6e-17 62.2 4.2 6.1e-17 61.5 2.4 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO30314.1 - 2.6e-06 27.3 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO30314.1 - 0.00037 20.9 0.0 0.00066 20.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGO30314.1 - 0.0095 15.4 0.3 4.3 6.8 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EGO30314.1 - 0.014 15.0 0.3 0.034 13.7 0.2 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 cobW PF02492.14 EGO30314.1 - 0.018 14.4 0.4 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EGO30314.1 - 0.19 11.1 1.6 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L32e PF01655.13 EGO30317.1 - 7.8e-46 154.6 1.7 9.2e-46 154.4 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 SoxE PF06525.6 EGO30318.1 - 0.053 12.7 1.8 0.23 10.7 1.3 1.9 2 0 0 2 2 2 0 Sulfocyanin (SoxE) K1377 PF15352.1 EGO30318.1 - 6.2 4.6 7.6 6.5 4.5 0.0 2.0 2 0 0 2 2 2 0 Susceptibility to monomelic amyotrophy PAH PF02671.16 EGO30319.1 - 1.2e-38 130.4 6.2 9.5e-15 53.9 1.2 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGO30319.1 - 2.4e-36 123.5 0.0 5.1e-36 122.4 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor zf-CCHC_3 PF13917.1 EGO30321.1 - 5.1e-06 26.1 2.9 1.1e-05 25.1 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO30321.1 - 2.7e-05 23.8 5.5 4.5e-05 23.1 3.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO30321.1 - 0.15 11.6 3.6 0.28 10.6 2.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger O-antigen_lig PF13425.1 EGO30322.1 - 0.012 15.6 0.1 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 O-antigen ligase like membrane protein DDE_Tnp_4 PF13359.1 EGO30323.1 - 3.4e-21 75.4 0.1 4.4e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 EGO30323.1 - 0.0043 16.4 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein ABC_membrane_3 PF13748.1 EGO30323.1 - 0.018 14.0 0.2 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Saw1 PF11561.3 EGO30324.1 - 1.6 8.0 0.0 1.6 8.0 0.0 2.5 2 1 0 2 2 2 0 Single strand annealing-weakened 1 DUF2457 PF10446.4 EGO30324.1 - 9.1 4.8 13.0 12 4.5 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NTP_transf_3 PF12804.2 EGO30325.1 - 0.018 15.1 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain IF4E PF01652.13 EGO30326.1 - 9.8e-49 165.0 0.0 1.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E zf-met PF12874.2 EGO30327.1 - 1.6e-06 28.1 1.2 2.8e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EGO30327.1 - 0.024 13.8 0.6 0.044 13.0 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DDE_3 PF13358.1 EGO30329.1 - 1.4e-13 50.8 0.0 1.9e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Ion_trans PF00520.26 EGO30329.1 - 0.059 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein UNC45-central PF11701.3 EGO30331.1 - 0.0022 17.6 0.2 0.8 9.3 0.0 2.7 2 2 0 2 2 2 2 Myosin-binding striated muscle assembly central zf-CCHC PF00098.18 EGO30333.1 - 0.00066 19.4 5.1 0.0013 18.5 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30333.1 - 0.0039 17.2 0.1 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-PHD-like PF15446.1 EGO30333.1 - 0.011 14.9 1.9 0.022 14.0 1.3 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain gag-asp_proteas PF13975.1 EGO30334.1 - 4.3e-10 39.2 0.0 5.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO30334.1 - 6.9e-08 32.5 0.0 7.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO30334.1 - 1.4e-06 28.6 0.0 2.4e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EGO30334.1 - 0.017 14.6 0.0 0.019 14.5 0.0 1.2 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EGO30336.1 - 1.9e-08 33.8 4.7 3.8e-08 32.8 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30336.1 - 1e-05 25.4 2.6 1.7e-05 24.7 0.3 2.2 1 1 0 2 2 2 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO30336.1 - 0.016 14.6 0.4 0.03 13.7 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO30336.1 - 0.26 11.0 5.5 0.77 9.5 3.8 1.8 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 EGO30337.1 - 1.6e-12 47.1 0.1 2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain UBN2_2 PF14227.1 EGO30338.1 - 1.2e-06 28.0 0.1 2.2e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO30338.1 - 1.4e-05 24.3 0.1 2.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EGO30338.1 - 4.4e-05 23.2 0.0 9.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGO30338.1 - 7.6e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EGO30339.1 - 1.7e-07 30.9 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGO30339.1 - 2.2e-06 28.0 0.0 2.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO30339.1 - 9e-06 25.6 0.0 9.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Phenyl_P_gamma PF09662.5 EGO30339.1 - 0.067 12.9 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) SprB PF13573.1 EGO30339.1 - 2 8.1 4.7 9.5 5.9 3.3 2.0 1 1 0 1 1 1 0 SprB repeat NEAT PF05031.7 EGO30340.1 - 0.054 13.5 1.1 0.12 12.3 0.8 1.5 1 0 0 1 1 1 0 Iron Transport-associated domain Asp_protease_2 PF13650.1 EGO30341.1 - 0.00036 20.9 0.0 0.00062 20.2 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EGO30341.1 - 0.0016 18.3 0.1 0.083 12.8 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO30341.1 - 0.0025 17.6 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EGO30343.1 - 1.6e-10 40.9 2.2 2.9e-10 40.0 1.5 1.5 1 0 0 1 1 1 1 Transposase LexA_DNA_bind PF01726.11 EGO30343.1 - 0.017 14.6 0.3 0.65 9.5 0.1 2.3 1 1 0 2 2 2 0 LexA DNA binding domain Ig_Tie2_1 PF10430.4 EGO30343.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 DUF3145 PF11343.3 EGO30345.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Retrotrans_gag PF03732.12 EGO30345.1 - 0.021 14.8 0.2 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.18 EGO30345.1 - 0.021 14.7 2.6 0.045 13.6 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Nop53 PF07767.6 EGO30350.1 - 4e-69 233.4 7.0 4.9e-69 233.1 4.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) zf-CCHC_4 PF14392.1 EGO30351.1 - 0.085 12.5 3.5 0.16 11.6 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1212 PF06738.7 EGO30355.1 - 3.9e-28 98.2 3.8 5.4e-28 97.7 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) SNF2_N PF00176.18 EGO30356.1 - 1.8e-72 243.6 0.0 2.1e-71 240.1 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO30356.1 - 3.4e-11 42.8 0.0 6.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EGO30356.1 - 0.0043 16.7 5.3 0.011 15.3 3.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 EGO30356.1 - 0.013 15.2 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EGO30356.1 - 0.68 9.6 9.5 0.045 13.4 2.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HTH_OrfB_IS605 PF12323.3 EGO30359.1 - 0.03 13.6 0.1 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4422 PF14393.1 EGO30360.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Myb_DNA-bind_4 PF13837.1 EGO30362.1 - 0.00045 20.2 0.0 0.0013 18.8 0.0 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain WD40 PF00400.27 EGO30363.1 - 8.2e-05 22.3 0.0 0.0089 15.8 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2724 PF10893.3 EGO30364.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2724) PPR_2 PF13041.1 EGO30366.1 - 6.7e-05 22.7 0.0 0.0028 17.6 0.0 2.4 1 1 1 2 2 2 1 PPR repeat family PPR_3 PF13812.1 EGO30366.1 - 0.00017 21.6 0.1 0.0034 17.5 0.0 2.8 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 EGO30366.1 - 0.035 14.0 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 PPR repeat Cwf_Cwc_15 PF04889.7 EGO30368.1 - 8.8 5.9 9.7 16 5.1 6.7 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med15 PF09606.5 EGO30370.1 - 1.3 7.0 30.5 1.7 6.7 21.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FYDLN_acid PF09538.5 EGO30371.1 - 2.7 8.6 11.1 10 6.7 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Gemini_AL2 PF01440.11 EGO30371.1 - 4.9 7.2 10.8 0.25 11.4 0.9 2.2 2 0 0 2 2 2 0 Geminivirus AL2 protein Transposase_21 PF02992.9 EGO30372.1 - 6.1e-08 32.0 0.1 9.7e-08 31.3 0.1 1.2 1 0 0 1 1 1 1 Transposase family tnp2 HSP70 PF00012.15 EGO30373.1 - 4.1e-32 110.8 0.0 4.7e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HMG_box PF00505.14 EGO30374.1 - 0.013 15.7 1.6 0.017 15.4 0.3 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO30374.1 - 0.015 15.6 0.3 0.037 14.4 0.2 1.6 1 0 0 1 1 1 0 HMG-box domain AP4E_app_platf PF14807.1 EGO30374.1 - 0.05 13.8 0.4 0.05 13.8 0.3 1.9 1 1 1 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DUF1033 PF06279.6 EGO30374.1 - 0.099 12.4 4.1 0.15 11.9 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Sporozoite_P67 PF05642.6 EGO30374.1 - 0.19 9.5 6.2 0.2 9.4 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3490 PF11995.3 EGO30374.1 - 0.25 10.9 2.9 0.3 10.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) CTK3_C PF12350.3 EGO30374.1 - 0.48 10.4 4.0 1 9.4 0.4 2.1 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus DUF659 PF04937.10 EGO30378.1 - 4e-05 23.1 0.3 4e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) SeleniumBinding PF11524.3 EGO30378.1 - 0.042 13.9 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 Selenium binding protein BCAS2 PF05700.6 EGO30379.1 - 8.2e-37 126.8 1.0 1.1e-36 126.4 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_3 PF13415.1 EGO30382.1 - 7.4e-38 127.8 12.8 4.5e-09 36.2 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO30382.1 - 1.6e-32 110.9 7.3 4.3e-07 29.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EGO30382.1 - 1.3e-31 108.1 17.9 1.3e-08 34.5 0.7 6.9 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EGO30382.1 - 7.3e-30 101.8 3.0 2.4e-08 33.7 0.2 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EGO30382.1 - 1.5e-27 94.9 0.3 3.8e-06 26.3 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGO30382.1 - 7.9e-22 76.1 8.8 0.00054 19.6 0.1 6.6 6 0 0 6 6 6 6 Kelch motif RAG2 PF03089.9 EGO30382.1 - 0.073 11.7 1.4 13 4.4 0.0 3.6 3 1 1 4 4 4 0 Recombination activating protein 2 Retrotrans_gag PF03732.12 EGO30383.1 - 2.5e-08 33.8 0.3 2.5e-08 33.8 0.2 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein Cytokin_check_N PF10407.4 EGO30384.1 - 0.38 10.4 1.9 21 4.8 0.2 2.6 2 1 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus GF_recep_IV PF14843.1 EGO30387.1 - 0.041 13.4 0.2 0.042 13.4 0.2 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV DDE_Tnp_4 PF13359.1 EGO30387.1 - 0.061 12.9 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-CCHC_4 PF14392.1 EGO30389.1 - 0.079 12.6 3.5 0.15 11.7 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 EGO30390.1 - 0.033 14.1 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease ACC_epsilon PF13822.1 EGO30392.1 - 0.042 14.2 2.2 0.22 11.8 0.6 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit BMFP PF04380.8 EGO30392.1 - 0.072 13.2 1.1 2.9 8.0 0.3 2.2 2 0 0 2 2 2 0 Membrane fusogenic activity Peptidase_C32 PF05411.7 EGO30392.1 - 0.095 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase zf-CCHC PF00098.18 EGO30394.1 - 0.013 15.4 0.8 0.024 14.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Cript PF10235.4 EGO30394.1 - 0.11 12.8 3.0 0.28 11.5 2.0 1.8 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-CCHC_2 PF13696.1 EGO30394.1 - 0.12 11.9 0.5 0.19 11.2 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_2 PF08914.6 EGO30395.1 - 7.9e-10 38.3 0.5 2.2e-09 36.9 0.3 1.8 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EGO30395.1 - 2.6 8.6 10.0 0.28 11.7 1.4 3.1 3 1 0 3 3 3 0 Rap1, DNA-binding DUF2150 PF09920.4 EGO30398.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Methyltransf_8 PF05148.10 EGO30399.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Fork_head PF00250.13 EGO30402.1 - 5.5e-19 67.9 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Fork head domain AT_hook PF02178.14 EGO30402.1 - 6.5 6.7 21.0 0.86 9.4 0.3 3.5 3 0 0 3 3 3 0 AT hook motif 6PGD PF00393.14 EGO30404.1 - 2.4e-132 440.5 0.0 3.1e-132 440.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGO30404.1 - 2.8e-51 173.6 0.0 4e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EGO30404.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EGO30404.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EGO30404.1 - 0.018 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EGO30404.1 - 0.037 13.1 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGO30404.1 - 0.076 12.3 0.0 0.64 9.3 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Ras PF00071.17 EGO30405.1 - 2.6e-54 182.9 0.0 2.9e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO30405.1 - 9.3e-17 61.6 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO30405.1 - 3.2e-06 26.5 0.0 4.8e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family zf-CCHC PF00098.18 EGO30408.1 - 1.5e-07 30.9 3.3 2.9e-07 30.1 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30408.1 - 4.1e-06 26.7 0.5 4.1e-06 26.7 0.3 2.5 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 EGO30408.1 - 0.17 11.4 0.4 0.4 10.2 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO30411.1 - 5.9e-07 29.1 1.5 6.4e-07 28.9 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO30411.1 - 1.9e-05 24.3 5.5 2.5e-05 23.9 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGO30411.1 - 0.18 11.3 4.3 0.26 10.8 3.0 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 EGO30412.1 - 6 6.6 9.5 0.069 12.8 1.4 1.7 2 0 0 2 2 2 0 Zinc knuckle gag_pre-integrs PF13976.1 EGO30413.1 - 2.8e-08 33.2 0.1 4.3e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain Mgr1 PF08602.5 EGO30415.1 - 0.0093 15.0 0.2 0.012 14.6 0.2 1.1 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit GHL1-3 PF11308.3 EGO30415.1 - 0.068 12.4 0.1 0.13 11.6 0.0 1.5 1 1 1 2 2 2 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 MGC-24 PF05283.6 EGO30416.1 - 1 9.1 8.6 1.5 8.6 6.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Actin PF00022.14 EGO30417.1 - 6.2e-133 443.0 0.0 7.2e-133 442.8 0.0 1.0 1 0 0 1 1 1 1 Actin WD40 PF00400.27 EGO30418.1 - 1.9e-41 138.5 10.6 7.9e-09 35.0 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EGO30418.1 - 0.00012 21.6 0.0 0.0046 16.4 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 EGO30418.1 - 0.0074 14.6 0.0 1.2 7.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EGO30418.1 - 0.02 13.0 0.0 0.11 10.6 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HTH_23 PF13384.1 EGO30419.1 - 8.3e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain zf-FCS PF06467.9 EGO30421.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Retrotrans_gag PF03732.12 EGO30422.1 - 1.7e-09 37.6 0.7 6e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO30422.1 - 0.0012 18.7 3.7 0.0024 17.7 2.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO30422.1 - 0.061 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein BMFP PF04380.8 EGO30422.1 - 0.41 10.8 2.7 2.2 8.4 0.2 2.7 3 0 0 3 3 3 0 Membrane fusogenic activity gag_pre-integrs PF13976.1 EGO30423.1 - 1.1e-10 40.9 0.9 1.8e-10 40.3 0.5 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_4 PF14392.1 EGO30424.1 - 0.094 12.4 4.0 0.19 11.3 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle V-SNARE_C PF12352.3 EGO30425.1 - 1.7e-10 40.8 0.9 2.8e-10 40.0 0.2 1.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGO30425.1 - 0.086 12.5 0.2 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Sec20 FTA4 PF13093.1 EGO30425.1 - 0.1 12.0 1.4 0.17 11.3 0.8 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_C12 PF01088.16 EGO30428.1 - 0.0098 15.0 0.2 0.038 13.1 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HAUS6_N PF14661.1 EGO30428.1 - 0.065 12.5 2.5 0.13 11.5 1.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Retrotrans_gag PF03732.12 EGO30431.1 - 1.2e-06 28.4 1.8 1.2e-06 28.4 1.2 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein DUF4415 PF14384.1 EGO30431.1 - 0.73 10.0 0.0 0.73 10.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4415) UCR_14kD PF02271.11 EGO30432.1 - 0.022 14.5 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Cyclin_N PF00134.18 EGO30433.1 - 7.7e-38 128.9 0.4 1.6e-37 127.8 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO30433.1 - 9.4e-08 32.0 0.2 2.4e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain PGM_PMM_I PF02878.11 EGO30440.1 - 1.2e-18 66.9 0.4 4.9e-08 32.5 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGO30440.1 - 1.6e-12 47.6 0.0 5.5e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGO30440.1 - 5.2e-12 45.6 0.1 9.5e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EGO30440.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1793 PF08760.6 EGO30440.1 - 0.036 13.9 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) Asp_protease_2 PF13650.1 EGO30441.1 - 0.052 14.0 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 EGO30441.1 - 0.11 12.3 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 EGO30442.1 - 0.019 14.6 2.4 0.035 13.7 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle CD24 PF14984.1 EGO30442.1 - 0.87 9.4 8.1 1.9 8.3 5.6 1.6 1 0 0 1 1 1 0 CD24 protein DUF1162 PF06650.7 EGO30444.1 - 9.3e-55 185.7 0.0 2.6e-48 164.6 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGO30444.1 - 3.6e-28 97.4 0.0 1.7e-27 95.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGO30444.1 - 1.1e-07 31.8 0.1 3.5e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain ERM PF00769.14 EGO30447.1 - 0.0068 15.9 14.2 0.35 10.3 0.3 2.3 1 1 1 2 2 2 2 Ezrin/radixin/moesin family ATG16 PF08614.6 EGO30447.1 - 0.0097 15.7 8.3 0.0097 15.7 5.8 2.7 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.1 EGO30447.1 - 0.15 11.0 2.3 0.27 10.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EGO30447.1 - 2.5 7.8 18.3 7.5 6.3 7.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EGO30447.1 - 2.9 6.8 19.9 0.25 10.3 8.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 UBN2 PF14223.1 EGO30449.1 - 0.0016 18.1 0.1 0.0038 17.0 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGO30449.1 - 0.0086 15.6 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Ribosomal_S9 PF00380.14 EGO30450.1 - 9.6e-38 129.1 0.2 1.1e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.17 EGO30451.1 - 3.2e-55 186.5 0.0 3.8e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF713 PF05218.9 EGO30452.1 - 0.003 17.3 0.1 0.0042 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF713) KRAP_IP3R_bind PF14722.1 EGO30452.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 1 1 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain zf-CCHC PF00098.18 EGO30453.1 - 1.5e-08 34.1 1.5 3e-08 33.2 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30453.1 - 0.0053 16.7 9.2 0.0092 16.0 4.0 2.9 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EGO30453.1 - 0.25 11.0 1.4 0.51 10.0 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle gag_pre-integrs PF13976.1 EGO30454.1 - 5.4e-11 41.9 0.2 8.2e-11 41.3 0.2 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain HTH_23 PF13384.1 EGO30455.1 - 2e-09 36.7 0.1 2.6e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGO30455.1 - 2.3e-05 24.2 0.1 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EGO30455.1 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EGO30455.1 - 0.0026 16.9 0.1 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 EGO30455.1 - 0.0034 16.6 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family NUMOD1 PF07453.8 EGO30455.1 - 0.004 16.9 0.1 0.0081 15.9 0.1 1.4 1 0 0 1 1 1 1 NUMOD1 domain HTH_29 PF13551.1 EGO30455.1 - 0.0076 16.3 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.2 EGO30455.1 - 0.0077 16.4 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGO30455.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_1 PF01527.15 EGO30455.1 - 0.024 14.5 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Transposase Sigma70_ECF PF07638.6 EGO30455.1 - 0.09 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor Death PF00531.17 EGO30455.1 - 0.13 11.9 0.0 0.29 10.9 0.0 1.6 1 1 1 2 2 2 0 Death domain HTH_3 PF01381.17 EGO30455.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix SK_channel PF03530.9 EGO30456.1 - 2.2 8.1 7.0 0.13 12.0 0.8 2.0 2 1 0 2 2 2 0 Calcium-activated SK potassium channel SPRY PF00622.23 EGO30460.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 SPRY domain DUF4219 PF13961.1 EGO30462.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) SYCE1 PF15233.1 EGO30463.1 - 0.0041 17.0 3.3 0.0056 16.6 2.3 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Kinesin-relat_1 PF12711.2 EGO30463.1 - 0.0099 16.2 2.2 0.019 15.3 1.5 1.4 1 0 0 1 1 1 1 Kinesin motor DUF972 PF06156.8 EGO30463.1 - 0.013 15.8 1.6 0.017 15.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) BRE1 PF08647.6 EGO30463.1 - 0.019 14.9 6.2 0.043 13.7 4.3 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 EGO30463.1 - 0.022 14.6 3.0 0.027 14.3 2.1 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EGO30463.1 - 0.053 13.2 1.3 0.053 13.2 0.9 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Lzipper-MIP1 PF14389.1 EGO30463.1 - 0.081 13.0 3.4 0.18 11.9 2.4 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4570 PF15134.1 EGO30463.1 - 0.14 12.0 3.3 0.2 11.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) bZIP_2 PF07716.10 EGO30463.1 - 0.17 11.7 2.8 0.34 10.7 1.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF904 PF06005.7 EGO30463.1 - 0.18 12.0 8.7 0.23 11.7 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Spectrin PF00435.16 EGO30463.1 - 0.23 11.7 5.0 0.33 11.2 3.4 1.2 1 0 0 1 1 1 0 Spectrin repeat IncA PF04156.9 EGO30463.1 - 0.45 10.0 4.8 0.54 9.8 3.3 1.1 1 0 0 1 1 1 0 IncA protein Ribosomal_S28e PF01200.13 EGO30464.1 - 8.8e-33 111.8 1.2 9.5e-33 111.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HypA PF01155.14 EGO30467.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FAM101 PF15068.1 EGO30468.1 - 0.14 11.6 1.0 0.16 11.3 0.7 1.1 1 0 0 1 1 1 0 FAM101 family DUF4111 PF13427.1 EGO30469.1 - 0.095 12.5 0.2 0.3 10.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Y_phosphatase3C PF13348.1 EGO30471.1 - 0.048 13.7 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region HiaBD2 PF15403.1 EGO30471.1 - 0.073 13.2 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) zf-CCHC PF00098.18 EGO30474.1 - 1e-05 25.2 2.3 2.1e-05 24.2 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO30474.1 - 0.0027 17.4 3.0 0.0076 15.9 2.1 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30474.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_6 PF15288.1 EGO30474.1 - 0.049 13.3 0.4 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RhoGAP PF00620.22 EGO30477.1 - 0.026 14.1 0.2 0.16 11.5 0.0 2.3 3 1 0 3 3 3 0 RhoGAP domain SH3_5 PF08460.5 EGO30477.1 - 0.032 14.1 0.2 0.084 12.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain TAXi_C PF14541.1 EGO30477.1 - 0.057 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF1904 PF08921.6 EGO30477.1 - 0.08 12.9 0.1 5.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1904) PA26 PF04636.8 EGO30478.1 - 0.0053 15.5 0.1 0.0081 14.8 0.1 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) HTH_32 PF13565.1 EGO30479.1 - 0.043 14.5 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_33 PF13592.1 EGO30479.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix PIF1 PF05970.9 EGO30481.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 EGO30481.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGO30481.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGO30481.1 - 0.026 13.3 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 EGO30481.1 - 0.062 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EGO30481.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 EGO30481.1 - 0.15 10.9 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Helitron_like_N PF14214.1 EGO30482.1 - 2.1e-09 37.3 0.0 4.9e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cyclin_N PF00134.18 EGO30483.1 - 2.4e-28 98.2 0.8 2.4e-28 98.2 0.5 1.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO30483.1 - 1.6e-12 47.4 0.4 4e-12 46.0 0.0 1.8 2 1 1 3 3 3 1 Cyclin, C-terminal domain DUF3893 PF13032.1 EGO30483.1 - 0.071 13.2 0.1 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3893) RNase_T PF00929.19 EGO30484.1 - 2.3e-08 34.5 0.0 2.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DDE_3 PF13358.1 EGO30487.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_29 PF13551.1 EGO30488.1 - 0.00019 21.5 0.2 0.00027 21.0 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EGO30488.1 - 0.00041 20.3 0.4 0.017 15.1 0.0 2.4 3 0 0 3 3 3 1 Transposase HTH_32 PF13565.1 EGO30488.1 - 0.0013 19.4 0.1 0.0022 18.7 0.1 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGO30488.1 - 0.0063 16.4 0.1 0.013 15.5 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain DUF746 PF05344.6 EGO30488.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_Crp_2 PF13545.1 EGO30488.1 - 0.062 13.0 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain NIPSNAP PF07978.8 EGO30489.1 - 2.3e-30 104.5 2.1 1.3e-25 89.3 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Retrotrans_gag PF03732.12 EGO30490.1 - 2.8e-08 33.6 0.5 1.7e-07 31.2 0.0 2.5 3 0 0 3 3 3 1 Retrotransposon gag protein RVP_2 PF08284.6 EGO30491.1 - 0.034 14.0 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RIO1 PF01163.17 EGO30494.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Inhibitor_I71 PF12628.2 EGO30495.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor TSC22 PF01166.13 EGO30495.1 - 2.1 8.3 5.1 7.7 6.5 2.9 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF1421 PF07223.6 EGO30497.1 - 0.018 14.8 0.1 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) CBS PF00571.23 EGO30498.1 - 4.5e-35 119.1 11.7 2e-09 37.0 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EGO30498.1 - 5.2e-09 35.6 0.0 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain KdpC PF02669.10 EGO30498.1 - 0.019 14.6 0.1 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 K+-transporting ATPase, c chain Myb_DNA-bind_3 PF12776.2 EGO30499.1 - 0.04 14.5 1.8 0.13 12.9 0.1 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0052 PF01933.13 EGO30500.1 - 1.1 8.4 4.9 0.8 8.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 Trypan_PARP PF05887.6 EGO30500.1 - 5.6 6.7 9.6 11 5.8 6.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tim54 PF11711.3 EGO30500.1 - 5.8 5.4 10.0 19 3.6 6.9 1.8 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Packaging_FI PF14000.1 EGO30500.1 - 5.8 7.1 11.2 2.7 8.1 4.9 2.0 2 0 0 2 2 2 0 DNA packaging protein FI Vfa1 PF08432.5 EGO30500.1 - 7.3 6.5 13.1 2.2 8.2 5.2 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4484 PF14831.1 EGO30500.1 - 7.4 6.6 7.6 2.3 8.2 3.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DDE_1 PF03184.14 EGO30501.1 - 5.3e-09 35.5 0.1 6.9e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CT47 PF15623.1 EGO30501.1 - 0.17 11.6 0.1 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 zf-CCHC PF00098.18 EGO30503.1 - 9.9e-06 25.2 4.7 2.4e-05 24.0 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30503.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 EGO30503.1 - 0.024 14.1 0.9 0.059 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 EGO30504.1 - 0.00031 21.1 0.0 0.00035 21.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO30504.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO30504.1 - 0.0042 17.0 0.0 0.0092 15.9 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Pal1 PF08316.6 EGO30505.1 - 0.025 15.0 0.9 0.04 14.3 0.1 1.7 2 0 0 2 2 2 0 Pal1 cell morphology protein RNA12 PF10443.4 EGO30511.1 - 0.028 12.9 0.1 0.028 12.9 0.1 1.0 1 0 0 1 1 1 0 RNA12 protein DUF523 PF04463.7 EGO30511.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF523) DUF2326 PF10088.4 EGO30512.1 - 0.16 11.5 1.5 0.28 10.7 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2326) WD40 PF00400.27 EGO30513.1 - 4.5e-24 83.3 16.7 3.5e-07 29.8 0.9 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO30513.1 - 0.012 13.7 0.0 0.82 7.7 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGO30513.1 - 0.21 9.8 7.1 0.67 8.1 0.1 3.6 3 1 0 4 4 4 0 Cytochrome D1 heme domain UcrQ PF02939.11 EGO30514.1 - 0.023 14.5 1.9 0.023 14.5 1.3 1.9 1 1 1 2 2 2 0 UcrQ family DUF3816 PF12822.2 EGO30514.1 - 0.026 14.4 0.6 0.031 14.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF3201 PF11447.3 EGO30515.1 - 0.0014 18.0 0.6 0.0048 16.3 0.2 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3201) SlyX PF04102.7 EGO30515.1 - 0.15 12.4 1.0 0.28 11.5 0.7 1.4 1 0 0 1 1 1 0 SlyX zinc-ribbons_6 PF07191.7 EGO30516.1 - 0.082 12.7 1.5 7.1 6.4 0.0 2.3 2 1 0 2 2 2 0 zinc-ribbons IFT57 PF10498.4 EGO30518.1 - 0.053 12.2 0.2 0.052 12.2 0.1 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tet_JBP PF12851.2 EGO30519.1 - 0.13 11.5 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily APC_CDC26 PF10471.4 EGO30520.1 - 0.039 14.6 0.1 0.065 13.9 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 WD40 PF00400.27 EGO30521.1 - 2.1e-06 27.3 0.0 9.6e-05 22.1 0.0 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat RVP_2 PF08284.6 EGO30524.1 - 0.0063 16.4 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Imm_superinfect PF14373.1 EGO30524.1 - 0.026 14.1 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Superinfection immunity protein TerD PF02342.13 EGO30524.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 TerD domain BAH PF01426.13 EGO30528.1 - 0.00022 20.9 0.0 0.0029 17.3 0.0 2.3 1 1 0 2 2 2 1 BAH domain U3snoRNP10 PF12397.3 EGO30528.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 EnY2 PF10163.4 EGO30529.1 - 0.052 13.4 0.1 8.1 6.4 0.0 2.3 1 1 1 2 2 2 0 Transcription factor e(y)2 PHD PF00628.24 EGO30530.1 - 3.7e-10 39.3 6.4 3.7e-10 39.3 4.4 2.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGO30530.1 - 2 7.7 11.3 0.15 11.4 1.8 3.1 3 0 0 3 3 3 0 PHD-finger LSM PF01423.17 EGO30531.1 - 4.2e-16 58.2 0.2 5.6e-16 57.8 0.2 1.2 1 0 0 1 1 1 1 LSM domain PolC_DP2 PF03833.8 EGO30535.1 - 4.7 4.7 11.0 5.9 4.4 7.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF4218 PF13960.1 EGO30536.1 - 0.00057 19.3 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) Cnd2 PF05786.9 EGO30537.1 - 0.0059 15.1 0.3 0.0067 15.0 0.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 ThiS-like PF14453.1 EGO30537.1 - 0.037 13.8 1.8 1.6 8.6 0.4 2.2 2 0 0 2 2 2 0 ThiS-like ubiquitin Fibrinogen_aC PF12160.3 EGO30537.1 - 0.28 10.6 2.2 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha C domain Pkinase PF00069.20 EGO30538.1 - 6.1e-12 45.2 0.2 1.7e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30538.1 - 0.0031 16.6 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Imm31 PF15595.1 EGO30538.1 - 0.066 12.9 0.2 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 31 Ima1_N PF09779.4 EGO30539.1 - 2.1e-27 96.2 3.7 3.2e-27 95.5 2.6 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain PYRIN PF02758.11 EGO30541.1 - 0.0017 18.0 0.5 0.0031 17.1 0.4 1.5 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain DZR PF12773.2 EGO30543.1 - 0.43 10.4 5.0 1.2 9.0 3.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGO30543.1 - 0.77 9.0 6.2 2.7 7.2 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGO30543.1 - 9.7 5.8 7.0 1.3 8.5 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 EGO30545.1 - 0.89 10.0 9.9 2 8.9 6.9 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2321 PF10083.4 EGO30546.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Ras PF00071.17 EGO30549.1 - 2e-50 170.3 0.1 2.3e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO30549.1 - 2.7e-15 56.8 0.0 3.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO30549.1 - 4.4e-05 22.7 0.0 4.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO30549.1 - 0.00021 20.7 0.0 0.00044 19.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO30549.1 - 0.0006 19.7 0.0 0.00088 19.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RepB PF07506.6 EGO30549.1 - 0.021 14.6 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein FeoB_N PF02421.13 EGO30549.1 - 0.055 12.7 0.0 0.75 9.0 0.0 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.1 EGO30549.1 - 0.085 12.4 0.1 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EGO30549.1 - 0.12 11.4 0.0 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 KaiC DDE_1 PF03184.14 EGO30550.1 - 2.6e-10 39.8 0.0 5.3e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease ChaC PF04752.7 EGO30551.1 - 0.14 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 ChaC-like protein zf-CCCH PF00642.19 EGO30555.1 - 1.9e-20 72.0 13.9 1.2e-11 43.9 1.8 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO30555.1 - 0.0027 17.6 9.9 0.0074 16.2 0.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHH PF10283.4 EGO30555.1 - 5 7.0 10.2 11 5.9 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif INCENP_ARK-bind PF03941.10 EGO30557.1 - 8.6e-17 60.7 0.2 1.3e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region PepSY_TM_1 PF13172.1 EGO30558.1 - 1.2 8.9 4.1 3 7.7 2.8 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix Oxidored_molyb PF00174.14 EGO30559.1 - 0.08 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain gag-asp_proteas PF13975.1 EGO30563.1 - 2.4e-08 33.6 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO30563.1 - 2.3e-07 30.8 0.0 2.5e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO30563.1 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Zn_Tnp_IS91 PF14319.1 EGO30564.1 - 0.052 13.0 3.5 0.11 11.9 2.4 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_3 PF13917.1 EGO30564.1 - 0.077 12.7 5.2 0.2 11.4 3.6 1.7 1 0 0 1 1 1 0 Zinc knuckle DZR PF12773.2 EGO30564.1 - 0.12 12.1 3.6 0.45 10.3 2.5 2.0 1 0 0 1 1 1 0 Double zinc ribbon zf-C4pol PF14260.1 EGO30564.1 - 0.21 11.6 3.1 0.5 10.3 0.8 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Myb_DNA-bind_3 PF12776.2 EGO30570.1 - 0.02 15.4 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-HC2 PF13490.1 EGO30573.1 - 3.4 7.7 7.8 0.11 12.5 1.1 1.7 2 0 0 2 2 2 0 Putative zinc-finger Pam16 PF03656.8 EGO30574.1 - 0.029 14.1 0.7 0.057 13.2 0.5 1.4 1 0 0 1 1 1 0 Pam16 Pantoate_ligase PF02569.10 EGO30574.1 - 0.26 10.0 2.5 0.47 9.1 1.7 1.5 1 1 0 1 1 1 0 Pantoate-beta-alanine ligase DUF3140 PF11338.3 EGO30574.1 - 2.4 8.3 7.0 1.2 9.3 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3140) TB2_DP1_HVA22 PF03134.14 EGO30576.1 - 2.8e-10 39.7 0.1 3.1e-10 39.6 0.1 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.9 EGO30576.1 - 0.025 14.5 0.1 0.025 14.5 0.1 1.0 1 0 0 1 1 1 0 GtrA-like protein Aa_trans PF01490.13 EGO30576.1 - 0.087 11.2 1.0 0.091 11.2 0.7 1.0 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein TMEM237 PF15383.1 EGO30576.1 - 0.096 11.8 0.1 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 Sec3_C PF09763.4 EGO30577.1 - 2.6e-145 485.3 6.4 2.3e-134 449.1 2.4 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EGO30577.1 - 4.6e-20 71.2 0.0 9.4e-20 70.2 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF605 PF04652.11 EGO30577.1 - 0.89 8.8 10.7 1.6 8.0 7.4 1.3 1 0 0 1 1 1 0 Vta1 like DDE_1 PF03184.14 EGO30578.1 - 3.4e-06 26.3 0.0 6.7e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease PcfK PF14058.1 EGO30578.1 - 0.029 14.5 0.6 0.046 13.8 0.4 1.3 1 0 0 1 1 1 0 PcfK-like protein ATP-grasp_2 PF08442.5 EGO30579.1 - 1.1e-70 237.1 0.4 2e-70 236.2 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGO30579.1 - 2.5e-24 85.6 0.1 4.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EGO30579.1 - 2.5e-14 53.0 0.2 6.8e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGO30579.1 - 0.00038 20.2 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EGO30579.1 - 0.0027 17.2 0.0 0.023 14.2 0.0 2.2 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EGO30579.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 EGO30579.1 - 0.012 14.9 0.4 0.09 12.0 0.1 2.3 1 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EGO30579.1 - 0.04 13.2 0.1 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain DUF4219 PF13961.1 EGO30581.1 - 0.068 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EGO30581.1 - 0.082 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF3586 PF12131.3 EGO30582.1 - 0.0058 16.6 0.5 0.0066 16.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Ribosomal_S17 PF00366.15 EGO30587.1 - 7.6e-30 102.7 0.4 7.6e-30 102.7 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Peptidase_S9_N PF02897.10 EGO30592.1 - 0.14 10.6 0.3 0.19 10.2 0.2 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Retrotrans_gag PF03732.12 EGO30593.1 - 0.0021 18.0 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Sigma54_AID PF00309.15 EGO30594.1 - 0.0081 15.6 0.4 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) PI-PLC-X PF00388.14 EGO30594.1 - 0.043 13.2 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain zf-CCHC PF00098.18 EGO30595.1 - 0.0017 18.1 0.9 0.003 17.4 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle DDE_1 PF03184.14 EGO30597.1 - 1.7e-28 99.2 0.0 3.1e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EGO30597.1 - 1.9e-08 34.1 0.1 4.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease CBFB_NFYA PF02045.10 EGO30601.1 - 0.096 13.2 0.2 0.096 13.2 0.1 2.5 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MCM PF00493.18 EGO30603.1 - 7.9e-125 416.0 0.1 1.2e-124 415.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO30603.1 - 6.8e-23 81.4 0.0 1.6e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO30603.1 - 2e-08 33.6 0.2 2e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGO30603.1 - 0.004 16.7 0.0 0.0094 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGO30603.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain APC_CDC26 PF10471.4 EGO30603.1 - 0.17 12.6 5.3 1.5 9.6 1.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RVP_2 PF08284.6 EGO30605.1 - 0.00094 19.1 0.1 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_1 PF03184.14 EGO30606.1 - 3.8e-06 26.1 0.1 5.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease gag_pre-integrs PF13976.1 EGO30608.1 - 2.3e-10 39.9 0.0 3.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EGO30609.1 - 1.8e-08 33.9 1.5 3.5e-08 32.9 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30609.1 - 8.3e-05 22.5 2.9 0.00039 20.4 2.0 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EGO30609.1 - 2.1 8.0 4.1 4.2 7.1 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO30610.1 - 0.023 14.7 0.0 0.064 13.3 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Nucleoporin_C PF03177.9 EGO30616.1 - 1.4e-71 241.7 0.0 2e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGO30616.1 - 4.3e-57 193.7 0.3 6.3e-57 193.2 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Chromo PF00385.19 EGO30617.1 - 2.2e-09 36.8 0.1 2.9e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain eIF2A PF08662.6 EGO30620.1 - 3.9e-43 147.4 1.5 2.3e-39 135.0 0.0 4.6 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGO30620.1 - 3.2e-06 26.7 4.2 0.23 11.3 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat RRM_6 PF14259.1 EGO30620.1 - 0.00023 21.0 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) gag-asp_proteas PF13975.1 EGO30625.1 - 0.00061 19.5 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EGO30625.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO30625.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 EGO30626.1 - 0.068 13.0 0.1 0.077 12.9 0.1 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease UBN2 PF14223.1 EGO30628.1 - 0.023 14.4 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGO30628.1 - 0.085 12.4 0.3 6.6 6.2 0.1 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type MoaC PF01967.16 EGO30629.1 - 1.2e-39 135.0 0.5 1.9e-37 127.9 0.4 2.5 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EGO30629.1 - 1e-36 125.4 0.0 1.8e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGO30629.1 - 3.9e-20 72.6 0.0 6.5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGO30629.1 - 1.2e-05 25.4 0.0 3.2e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGO30629.1 - 9.8e-05 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain RNA_pol_Rpb1_4 PF05000.12 EGO30629.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Chitin_synth_2 PF03142.10 EGO30630.1 - 4.1e-11 41.9 1.1 1e-10 40.6 0.0 1.8 1 1 0 2 2 2 1 Chitin synthase DDE_1 PF03184.14 EGO30631.1 - 2.4e-06 26.8 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2274 PF10038.4 EGO30631.1 - 0.035 14.2 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) Pal1 PF08316.6 EGO30632.1 - 3.4e-16 59.9 0.4 1.7e-15 57.6 0.1 2.2 1 1 0 1 1 1 1 Pal1 cell morphology protein gag_pre-integrs PF13976.1 EGO30635.1 - 4.7e-09 35.7 0.1 7.2e-09 35.1 0.1 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain DENN PF02141.16 EGO30639.1 - 3.1e-18 66.1 0.0 6.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain TYA PF01021.14 EGO30639.1 - 0.024 14.8 0.0 0.089 13.0 0.0 2.0 1 0 0 1 1 1 0 TYA transposon protein Syntaxin PF00804.20 EGO30641.1 - 5e-16 58.7 6.9 7.5e-16 58.1 1.3 2.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EGO30641.1 - 1e-14 53.9 2.0 2e-14 53.0 0.2 2.4 2 0 0 2 2 2 1 SNARE domain Sed5p PF11416.3 EGO30641.1 - 0.0085 15.4 0.0 0.023 14.1 0.0 1.8 1 0 0 1 1 1 1 Integral membrane protein Sed5p zf-C4H2 PF10146.4 EGO30641.1 - 0.026 14.5 0.8 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Med29 PF11568.3 EGO30641.1 - 0.053 13.5 5.9 0.14 12.1 0.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 29 Syntaxin-18_N PF10496.4 EGO30641.1 - 0.087 12.6 1.5 0.44 10.4 0.1 2.7 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Atg14 PF10186.4 EGO30641.1 - 0.62 8.9 7.9 2.6 6.9 1.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EGO30641.1 - 1.6 8.5 7.0 2.2 8.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EGO30641.1 - 4.4 7.6 7.4 2.7 8.2 0.8 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3388 PF11868.3 EGO30643.1 - 0.11 11.6 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) SRC-1 PF08832.5 EGO30643.1 - 0.17 12.6 0.7 1.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Steroid receptor coactivator FRG2 PF15315.1 EGO30644.1 - 3.4 7.5 8.1 2.3 8.1 4.6 1.5 1 1 1 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 RNase_H2-Ydr279 PF09468.5 EGO30644.1 - 4 6.5 7.9 4.6 6.3 5.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4473 PF14747.1 EGO30645.1 - 0.033 14.3 0.1 0.08 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) M11L PF11099.3 EGO30646.1 - 0.0094 15.6 0.2 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Apoptosis regulator M11L like TAF1_subA PF14929.1 EGO30646.1 - 0.01 14.2 0.4 0.011 14.2 0.3 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Pkinase PF00069.20 EGO30647.1 - 9.6e-56 188.7 0.0 2.1e-55 187.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30647.1 - 3.4e-23 82.0 0.0 6.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 EGO30648.1 - 1.4e-05 23.9 15.1 0.00061 18.5 10.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Tet_JBP PF12851.2 EGO30648.1 - 0.012 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DDE_Tnp_4 PF13359.1 EGO30651.1 - 9.2e-28 96.8 0.0 1.2e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGO30651.1 - 1.4e-05 24.7 0.0 0.00099 18.7 0.0 2.0 2 0 0 2 2 2 2 Transposase DDE domain DUF2457 PF10446.4 EGO30653.1 - 0.00048 18.9 15.7 0.00053 18.8 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) BUD22 PF09073.5 EGO30653.1 - 0.0015 17.6 7.1 0.0016 17.5 4.9 1.0 1 0 0 1 1 1 1 BUD22 RRN3 PF05327.6 EGO30653.1 - 0.0016 16.6 7.2 0.0018 16.4 5.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 EGO30653.1 - 0.0035 16.5 10.8 0.0038 16.4 7.5 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EGO30653.1 - 0.015 13.7 13.0 0.015 13.7 9.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EGO30653.1 - 0.022 14.1 7.0 0.024 13.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 EGO30653.1 - 0.023 14.6 15.1 0.027 14.4 10.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop25 PF09805.4 EGO30653.1 - 0.036 14.1 9.4 0.042 13.9 6.5 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Pox_Ag35 PF03286.9 EGO30653.1 - 0.037 13.5 5.6 0.047 13.2 3.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DARPP-32 PF05395.7 EGO30653.1 - 0.042 14.0 3.4 0.048 13.8 2.3 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Sigma70_ner PF04546.8 EGO30653.1 - 0.05 13.2 9.7 0.068 12.7 6.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.7 EGO30653.1 - 0.072 11.4 13.1 0.088 11.1 9.0 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF2722 PF10846.3 EGO30653.1 - 0.11 11.4 5.0 0.12 11.3 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PBP_sp32 PF07222.7 EGO30653.1 - 0.13 11.4 5.6 0.17 11.0 3.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TRAP_alpha PF03896.11 EGO30653.1 - 0.16 10.9 7.4 0.17 10.8 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 EGO30653.1 - 0.22 11.3 8.2 0.31 10.8 5.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PDCD2_C PF04194.8 EGO30653.1 - 0.24 10.9 3.6 0.29 10.7 2.5 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CDC45 PF02724.9 EGO30653.1 - 0.27 9.2 11.9 0.33 8.9 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EGO30653.1 - 0.43 9.7 6.0 0.46 9.6 4.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Prog_receptor PF02161.10 EGO30653.1 - 0.46 9.2 4.4 0.53 9.0 3.0 1.0 1 0 0 1 1 1 0 Progesterone receptor Rhabdo_ncap PF00945.13 EGO30653.1 - 0.49 8.9 4.3 0.51 8.8 3.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FAM176 PF14851.1 EGO30653.1 - 0.52 9.9 8.7 0.98 9.0 6.0 1.5 1 1 0 1 1 1 0 FAM176 family TLP-20 PF06088.6 EGO30653.1 - 0.58 9.8 5.5 0.96 9.0 3.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SDA1 PF05285.7 EGO30653.1 - 0.69 9.1 12.6 0.68 9.1 8.7 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.5 EGO30653.1 - 2.2 8.2 9.3 3 7.8 6.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 EGO30653.1 - 2.8 5.7 18.3 3.2 5.5 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EGO30653.1 - 2.9 7.0 15.5 3.6 6.7 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.8 EGO30653.1 - 3.1 5.4 16.3 3.6 5.2 11.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi COPI_C PF06957.6 EGO30653.1 - 4.6 5.6 7.1 4.6 5.6 5.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Sporozoite_P67 PF05642.6 EGO30653.1 - 5.9 4.6 9.4 8.8 4.0 6.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EGO30653.1 - 6.5 6.2 18.7 10 5.6 12.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Cytomega_UL84 PF06284.6 EGO30653.1 - 7.1 4.9 6.1 8.4 4.6 4.3 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein BTV_NS2 PF04514.7 EGO30653.1 - 8.5 5.1 9.8 10 4.8 6.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tom22 PF04281.8 EGO30653.1 - 9.2 5.8 8.9 13 5.3 6.2 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF929 PF06053.6 EGO30654.1 - 6.8 5.6 9.5 1.9 7.5 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF929) RhoGEF PF00621.15 EGO30655.1 - 4.1e-44 150.6 0.0 6.3e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EGO30655.1 - 2.2e-08 33.5 5.4 0.00054 19.5 0.1 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO30655.1 - 1.8e-06 27.5 10.2 0.00068 19.3 1.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EGO30655.1 - 0.042 13.8 9.1 12 6.4 0.4 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat RVP_2 PF08284.6 EGO30657.1 - 2.6e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO30657.1 - 0.038 14.4 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EGO30658.1 - 2.9e-07 30.1 0.9 5.3e-07 29.2 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30658.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein ARGLU PF15346.1 EGO30661.1 - 0.0011 18.7 13.4 0.0011 18.7 9.3 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 DUF3523 PF12037.3 EGO30661.1 - 0.011 14.7 12.7 0.013 14.5 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Cnd1_N PF12922.2 EGO30661.1 - 0.046 13.3 1.7 0.05 13.2 1.2 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF106 PF01956.11 EGO30661.1 - 0.057 12.9 3.9 0.066 12.7 2.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 CIAPIN1 PF05093.8 EGO30661.1 - 0.067 13.2 1.1 0.075 13.1 0.8 1.1 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Sin_N PF04801.8 EGO30661.1 - 0.11 11.3 6.4 0.12 11.2 4.4 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region SIR2 PF02146.12 EGO30661.1 - 0.15 11.8 2.4 0.25 11.0 1.7 1.3 1 1 0 1 1 1 0 Sir2 family Trypan_glycop_C PF10659.4 EGO30661.1 - 0.23 11.7 7.7 0.29 11.4 5.4 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain YqfQ PF14181.1 EGO30661.1 - 0.28 11.1 4.2 0.29 11.1 2.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein TP53IP5 PF15331.1 EGO30661.1 - 0.39 10.5 6.3 0.42 10.4 4.4 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Vfa1 PF08432.5 EGO30661.1 - 0.4 10.6 8.9 0.46 10.4 6.2 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BNR_3 PF13859.1 EGO30661.1 - 0.46 9.5 3.4 0.54 9.2 2.3 1.0 1 0 0 1 1 1 0 BNR repeat-like domain DUF1800 PF08811.6 EGO30661.1 - 0.6 8.9 5.4 0.64 8.8 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) RBM39linker PF15519.1 EGO30661.1 - 0.83 9.9 3.4 2.1 8.6 2.4 1.7 1 1 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein HNOBA PF07701.9 EGO30661.1 - 1 8.5 5.2 1.2 8.2 3.6 1.2 1 0 0 1 1 1 0 Heme NO binding associated DUF1525 PF07511.6 EGO30661.1 - 1.3 8.9 6.4 1.7 8.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Mitofilin PF09731.4 EGO30661.1 - 1.6 7.2 10.8 1.9 7.0 7.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.7 EGO30661.1 - 2.3 8.0 8.6 2.5 7.9 5.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3987 PF13148.1 EGO30661.1 - 3.1 6.2 10.9 3.4 6.1 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3584 PF12128.3 EGO30661.1 - 3.2 4.9 12.4 3.5 4.8 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NARP1 PF12569.3 EGO30661.1 - 3.5 6.2 10.9 3.6 6.2 7.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.11 EGO30661.1 - 3.8 6.8 6.2 4.2 6.7 4.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDRGK PF09756.4 EGO30661.1 - 3.8 6.8 14.2 4.5 6.6 9.9 1.1 1 0 0 1 1 1 0 DDRGK domain Bap31 PF05529.7 EGO30661.1 - 4.9 6.5 10.2 6.1 6.2 7.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4557 PF15101.1 EGO30661.1 - 9.8 5.9 7.6 11 5.7 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PIF1 PF05970.9 EGO30662.1 - 1.4e-10 40.6 0.1 2.5e-10 39.8 0.0 1.5 1 1 1 2 2 2 1 PIF1-like helicase MelC1 PF06236.6 EGO30662.1 - 0.13 12.2 1.0 0.89 9.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 WBS_methylT PF12589.3 EGO30662.1 - 0.75 10.3 7.6 1.1 9.8 5.3 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome ATP-synt_E PF05680.7 EGO30662.1 - 1.9 8.4 8.6 3.2 7.7 5.9 1.3 1 0 0 1 1 1 0 ATP synthase E chain RVP_2 PF08284.6 EGO30663.1 - 2.3e-05 24.3 0.1 0.0002 21.2 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGO30663.1 - 0.00014 22.3 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EGO30663.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EGO30664.1 - 1.6e-08 34.0 4.7 3.4e-08 33.0 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30664.1 - 9.9e-05 22.3 0.2 9.9e-05 22.3 0.1 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EGO30664.1 - 1 9.1 7.5 0.78 9.5 3.8 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_2 PF13923.1 EGO30665.1 - 4.6e-10 39.3 11.1 7.6e-10 38.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO30665.1 - 1.1e-09 37.7 9.1 2e-09 36.9 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO30665.1 - 4.2e-08 32.8 10.5 7e-08 32.1 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO30665.1 - 2.5e-06 27.0 5.7 4.2e-06 26.3 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO30665.1 - 2.3e-05 24.0 7.7 4.1e-05 23.2 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO30665.1 - 6e-05 22.8 10.8 0.00013 21.7 7.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO30665.1 - 0.00036 20.1 7.2 0.0016 18.0 5.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGO30665.1 - 0.0014 18.6 2.9 0.0031 17.5 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 EGO30665.1 - 0.0016 17.8 9.2 0.0031 16.9 6.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EGO30665.1 - 0.013 15.3 1.9 0.024 14.4 1.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGO30665.1 - 0.052 13.0 6.6 0.1 12.0 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGO30665.1 - 1.5 8.7 6.2 6 6.7 4.3 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein PAT1 PF09770.4 EGO30666.1 - 3.5 5.7 22.1 5.2 5.1 15.3 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cyclin_N PF00134.18 EGO30669.1 - 5.3e-43 145.6 1.7 5.5e-42 142.3 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO30669.1 - 9.8e-18 64.2 0.0 2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain NAD_Gly3P_dh_C PF07479.9 EGO30671.1 - 2.4e-49 166.8 0.1 3.3e-49 166.4 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EGO30671.1 - 1.4e-32 112.5 0.0 2.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EGO30671.1 - 1e-07 31.5 0.0 1.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EGO30671.1 - 2.9e-05 24.4 0.0 9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EGO30671.1 - 0.0061 16.9 0.0 5.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EGO30671.1 - 0.014 15.4 0.0 0.083 12.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 EGO30671.1 - 0.016 15.2 0.0 0.082 12.9 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 EGO30671.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EGO30671.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MRP-S33 PF08293.6 EGO30673.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 DUF2529 PF10740.4 EGO30677.1 - 0.055 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) AIF_C PF14721.1 EGO30677.1 - 0.088 13.0 0.6 0.18 12.0 0.4 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term UBN2_2 PF14227.1 EGO30678.1 - 0.0018 17.8 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGO30678.1 - 0.0028 17.4 0.0 0.0029 17.3 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TAXi_C PF14541.1 EGO30680.1 - 0.02 14.4 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Ssl1 PF04056.9 EGO30682.1 - 0.023 14.3 0.4 0.032 13.8 0.3 1.2 1 0 0 1 1 1 0 Ssl1-like SMAP PF15477.1 EGO30683.1 - 0.018 15.3 0.1 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Small acidic protein family PBP_GOBP PF01395.17 EGO30685.1 - 0.025 14.2 0.8 0.032 13.8 0.6 1.2 1 0 0 1 1 1 0 PBP/GOBP family ERM PF00769.14 EGO30685.1 - 0.11 12.0 2.4 0.093 12.2 1.1 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Adaptin_N PF01602.15 EGO30686.1 - 4.1e-120 401.5 7.0 5e-120 401.3 4.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGO30686.1 - 9.6e-36 122.1 0.0 2.3e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGO30686.1 - 3.2e-16 59.6 0.0 6.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain RasGEF_N_2 PF14663.1 EGO30686.1 - 0.071 13.0 0.2 18 5.2 0.0 3.6 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cauli_VI PF01693.11 EGO30689.1 - 8.8e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin VanY PF02557.12 EGO30691.1 - 0.0073 16.1 2.8 0.091 12.6 2.0 2.0 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Chromo PF00385.19 EGO30692.1 - 0.0088 15.7 0.2 0.037 13.6 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Med5 PF08689.5 EGO30694.1 - 2.8e-19 68.4 6.0 3.5e-14 51.5 0.2 2.4 2 1 0 2 2 2 2 Mediator complex subunit Med5 Anticodon_1 PF08264.8 EGO30695.1 - 0.18 11.5 1.1 0.36 10.5 0.7 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Proteasome PF00227.21 EGO30698.1 - 3.8e-36 124.1 0.0 4.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_6 PF12697.2 EGO30704.1 - 3.8e-17 62.9 0.1 2.6e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO30704.1 - 8.9e-08 32.0 0.0 0.005 16.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO30704.1 - 8.9e-05 22.1 0.0 0.00011 21.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EGO30704.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4111 PF13427.1 EGO30706.1 - 0.049 13.4 0.4 0.22 11.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) DUF552 PF04472.7 EGO30706.1 - 0.14 12.0 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF552) Zn_clus PF00172.13 EGO30710.1 - 5.4e-08 32.6 5.0 7.6e-08 32.1 3.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_C PF00034.16 EGO30710.1 - 5.5 7.8 8.1 4.3 8.2 3.5 2.2 1 1 1 2 2 2 0 Cytochrome c Retrotrans_gag PF03732.12 EGO30711.1 - 6.3e-05 22.9 0.0 6.3e-05 22.9 0.0 2.8 2 1 1 3 3 3 1 Retrotransposon gag protein GMP_synt_C PF00958.17 EGO30712.1 - 0.057 13.1 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 GMP synthase C terminal domain Keratin PF02422.11 EGO30717.1 - 0.13 12.2 0.7 0.31 11.0 0.2 1.8 1 1 1 2 2 2 0 Keratin Septin PF00735.13 EGO30721.1 - 4e-108 360.7 0.8 5.3e-108 360.3 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGO30721.1 - 1.9e-05 24.6 0.0 4.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EGO30721.1 - 0.0008 20.2 0.7 0.015 16.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EGO30721.1 - 0.0031 16.6 0.3 0.014 14.5 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO30721.1 - 0.0034 17.2 3.5 0.52 10.1 0.0 2.9 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EGO30721.1 - 0.0037 16.7 0.1 0.051 13.0 0.0 2.4 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGO30721.1 - 0.0038 17.7 0.7 0.028 14.9 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EGO30721.1 - 0.0092 15.1 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EGO30721.1 - 0.01 15.3 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGO30721.1 - 0.052 13.6 0.1 0.34 11.0 0.0 2.3 3 1 0 3 3 3 0 AAA domain IIGP PF05049.8 EGO30721.1 - 0.078 11.7 0.0 0.2 10.4 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EGO30721.1 - 0.12 12.6 0.7 0.58 10.4 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Atg14 PF10186.4 EGO30721.1 - 1.2 8.0 7.6 1.7 7.4 5.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Transposase_21 PF02992.9 EGO30722.1 - 0.00012 21.2 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Vma12 PF11712.3 EGO30723.1 - 0.1 12.3 1.2 0.12 12.0 0.8 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FixQ PF05545.6 EGO30723.1 - 0.42 10.3 1.8 0.66 9.6 1.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Zn_Tnp_IS91 PF14319.1 EGO30728.1 - 0.051 13.0 1.4 0.062 12.8 1.0 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-ribbon_3 PF13248.1 EGO30728.1 - 0.1 11.8 6.5 0.75 9.0 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGO30728.1 - 0.12 12.1 6.0 0.3 10.9 4.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EGO30728.1 - 1.7 8.2 7.1 0.86 9.1 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.21 EGO30730.1 - 0.021 15.1 1.4 0.034 14.4 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO30730.1 - 0.033 14.5 1.0 0.074 13.4 0.5 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger PGAP1 PF07819.8 EGO30731.1 - 3.3e-08 33.4 0.1 6.8e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO30731.1 - 9.2e-05 22.4 0.1 0.0019 18.1 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGO30731.1 - 0.00057 19.2 0.1 0.0015 17.8 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EGO30731.1 - 0.0013 17.8 0.0 0.0096 14.9 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EGO30731.1 - 0.002 17.9 0.0 0.004 16.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EGO30731.1 - 0.0028 16.7 0.0 0.01 14.9 0.0 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EGO30731.1 - 0.0069 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EGO30731.1 - 0.03 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RVT_2 PF07727.9 EGO30733.1 - 8.7e-10 37.9 0.0 9.4e-10 37.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Paramecium_SA PF01508.11 EGO30733.1 - 0.2 11.9 1.0 1.7 8.8 0.3 2.0 2 0 0 2 2 2 0 Paramecium surface antigen domain GTP_EFTU PF00009.22 EGO30734.1 - 5.5e-63 211.8 0.2 7.9e-63 211.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGO30734.1 - 7.4e-38 128.7 0.0 4.1e-37 126.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.19 EGO30734.1 - 3.8e-21 74.7 0.0 7.8e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGO30734.1 - 1.5e-12 47.1 0.0 4.5e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGO30734.1 - 1.7e-12 47.3 0.1 1.2e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO30734.1 - 7.1e-06 25.9 0.2 1.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGO30734.1 - 0.1 12.0 0.3 0.41 10.1 0.2 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HTH_Tnp_Tc3_2 PF01498.13 EGO30737.1 - 1.8e-09 37.4 1.6 2.8e-09 36.8 0.3 1.9 2 1 0 2 2 2 1 Transposase HTH_38 PF13936.1 EGO30737.1 - 7.6e-07 28.5 0.0 5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EGO30737.1 - 0.03 13.9 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.1 EGO30737.1 - 0.031 14.4 0.3 3.6 7.8 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.10 EGO30737.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Trp_repressor PF01371.14 EGO30737.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein Ig_Tie2_1 PF10430.4 EGO30737.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 B5 PF03484.10 EGO30737.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetase B5 domain SapB_2 PF03489.12 EGO30737.1 - 0.12 12.3 0.2 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 2 DDE_Tnp_4 PF13359.1 EGO30740.1 - 0.0068 16.0 0.0 0.0069 16.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribonucleas_3_3 PF14622.1 EGO30741.1 - 2.6e-08 33.8 0.0 4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EGO30741.1 - 2.1e-07 31.4 0.2 4.2e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EGO30741.1 - 0.0069 16.8 0.3 0.022 15.1 0.2 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Myco_arth_vir_N PF09610.5 EGO30743.1 - 2 8.4 4.1 3.6 7.6 2.9 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) ODR4-like PF14778.1 EGO30745.1 - 0.13 10.8 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like RRM_1 PF00076.17 EGO30746.1 - 3.8e-40 135.3 0.2 2.2e-20 72.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO30746.1 - 2e-30 104.5 0.1 3.3e-15 55.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO30746.1 - 9.5e-22 76.6 0.1 2.6e-08 33.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGO30746.1 - 4.3e-20 71.7 0.1 9.5e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EGO30746.1 - 8.1e-05 22.4 0.2 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif Imm_superinfect PF14373.1 EGO30747.1 - 0.073 12.7 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Superinfection immunity protein DUF4105 PF13387.1 EGO30749.1 - 8 5.6 7.6 2.4 7.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) Yippee-Mis18 PF03226.9 EGO30751.1 - 0.17 11.9 1.1 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myb_DNA-bind_3 PF12776.2 EGO30752.1 - 2.2e-07 31.4 0.2 0.00085 19.9 0.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain TRAM1 PF08390.6 EGO30754.1 - 0.04 13.4 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 TRAM1-like protein Het-C PF07217.6 EGO30755.1 - 0.12 10.5 0.4 0.16 10.0 0.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Cadherin_2 PF08266.7 EGO30755.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Cadherin-like GYF PF02213.11 EGO30756.1 - 4.3e-12 45.4 0.1 9.1e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 GYF domain DUF1593 PF07632.6 EGO30760.1 - 0.034 13.4 1.0 0.05 12.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) YlbD_coat PF14071.1 EGO30762.1 - 0.11 12.6 0.5 0.24 11.4 0.3 1.6 1 1 0 1 1 1 0 Putative coat protein Zn_Tnp_IS91 PF14319.1 EGO30764.1 - 0.0039 16.6 1.7 0.0068 15.9 1.1 1.4 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-C4pol PF14260.1 EGO30764.1 - 0.026 14.4 2.8 0.049 13.6 1.9 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-C4H2 PF10146.4 EGO30764.1 - 0.15 12.0 2.8 0.25 11.3 2.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein zf-ribbon_3 PF13248.1 EGO30764.1 - 0.2 10.9 6.2 1.6 8.0 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGO30764.1 - 0.21 11.4 7.1 0.41 10.5 4.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-CCHC_3 PF13917.1 EGO30764.1 - 0.24 11.1 9.7 0.43 10.3 6.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EGO30765.1 - 1.2e-09 38.1 1.5 2.8e-09 36.8 0.2 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EGO30765.1 - 1.5e-06 27.8 1.2 2.8e-06 26.9 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle ARGLU PF15346.1 EGO30766.1 - 0.077 12.7 2.1 0.086 12.6 1.4 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 YlbD_coat PF14071.1 EGO30767.1 - 0.037 14.1 1.8 0.11 12.5 1.3 1.8 1 0 0 1 1 1 0 Putative coat protein PSDC PF12588.3 EGO30767.1 - 0.07 12.7 1.4 14 5.2 0.0 3.2 3 0 0 3 3 3 0 Phophatidylserine decarboxylase NpwBP PF12622.2 EGO30770.1 - 1.1e-13 51.4 5.8 1.1e-13 51.4 4.0 3.3 3 1 0 3 3 3 1 mRNA biogenesis factor Wbp11 PF09429.5 EGO30770.1 - 1.8e-13 50.2 8.3 3.3e-13 49.4 5.8 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 MULE PF10551.4 EGO30771.1 - 1.8e-09 37.6 0.0 4.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Poty_PP PF08440.5 EGO30771.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Bowman-Birk_leg PF00228.15 EGO30774.1 - 0.081 12.7 0.2 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Aldolase_II PF00596.16 EGO30775.1 - 0.026 14.1 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Class II Aldolase and Adducin N-terminal domain 3H PF02829.9 EGO30776.1 - 0.028 14.4 0.4 0.038 14.0 0.3 1.2 1 0 0 1 1 1 0 3H domain DUF3073 PF11273.3 EGO30776.1 - 5.2 7.6 6.5 3.6 8.1 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) MCPVI PF02993.9 EGO30777.1 - 0.078 13.1 0.1 0.078 13.1 0.1 1.7 2 0 0 2 2 2 0 Minor capsid protein VI DDE_1 PF03184.14 EGO30778.1 - 8.6e-08 31.5 0.1 2.1e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease S1 PF00575.18 EGO30779.1 - 6.2e-53 176.7 26.5 4.9e-13 48.9 0.0 9.2 10 0 0 10 10 10 8 S1 RNA binding domain TPR_14 PF13428.1 EGO30779.1 - 1.6e-09 37.5 0.6 0.47 11.2 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO30779.1 - 3.4e-07 30.5 0.0 0.052 13.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO30779.1 - 3.6e-06 27.4 0.2 1.3 9.7 0.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO30779.1 - 9.1e-05 22.0 0.7 0.0036 16.9 0.6 2.9 2 1 0 2 2 2 1 TPR repeat NRDE-2 PF08424.5 EGO30779.1 - 0.0012 17.8 8.1 0.1 11.4 3.8 2.4 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EGO30779.1 - 0.0014 18.6 0.1 0.19 12.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO30779.1 - 0.0038 17.1 4.9 0.033 14.1 1.5 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGO30779.1 - 0.0099 14.9 2.4 0.54 9.2 0.2 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 EGO30779.1 - 0.01 15.5 3.7 0.49 10.0 0.0 3.6 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) Apc3 PF12895.2 EGO30779.1 - 0.052 13.6 0.5 0.14 12.3 0.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGO30779.1 - 0.076 12.9 4.2 12 6.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO30779.1 - 0.13 12.1 1.2 0.67 9.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO30779.1 - 0.28 10.8 1.8 1.3 8.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Latrotoxin_C PF15658.1 EGO30783.1 - 0.00079 19.2 0.1 0.0025 17.6 0.0 1.9 2 1 0 2 2 2 1 Latrotoxin C-terminal domain NfeD PF01957.13 EGO30788.1 - 0.035 14.2 0.1 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding SUR7 PF06687.7 EGO30788.1 - 0.11 11.9 11.1 0.18 11.3 7.7 1.3 1 0 0 1 1 1 0 SUR7/PalI family zf-C2H2_4 PF13894.1 EGO30795.1 - 0.012 15.8 0.1 0.051 13.9 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO30795.1 - 0.024 14.9 0.1 0.085 13.2 0.1 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3643 PF12356.3 EGO30795.1 - 0.12 11.6 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) Helitron_like_N PF14214.1 EGO30800.1 - 5.7e-53 179.3 0.1 8.5e-53 178.8 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 EGO30800.1 - 0.0029 17.1 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3296) Imm_superinfect PF14373.1 EGO30801.1 - 0.23 11.1 2.9 0.65 9.6 2.0 1.8 1 1 0 1 1 1 0 Superinfection immunity protein SNARE PF05739.14 EGO30805.1 - 0.00076 19.1 0.9 0.00099 18.7 0.6 1.2 1 0 0 1 1 1 1 SNARE domain EMP24_GP25L PF01105.19 EGO30805.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD zf-RING_2 PF13639.1 EGO30806.1 - 3.5e-13 49.1 4.3 3.5e-13 49.1 3.0 2.2 2 1 1 3 3 2 1 Ring finger domain zf-rbx1 PF12678.2 EGO30806.1 - 1.8e-11 43.9 1.0 1.8e-11 43.9 0.7 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGO30806.1 - 3.6e-07 29.7 3.6 3.6e-07 29.7 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO30806.1 - 1.3e-06 28.3 1.7 1.3e-06 28.3 1.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO30806.1 - 2e-06 27.3 1.6 2e-06 27.3 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO30806.1 - 2.3e-06 27.3 0.3 4.9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EGO30806.1 - 3.2e-06 26.7 2.5 3.2e-06 26.7 1.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 EGO30806.1 - 7.3e-06 25.8 1.4 7.3e-06 25.8 0.9 2.5 2 1 0 2 2 2 1 zinc-finger FANCL_C PF11793.3 EGO30806.1 - 0.018 15.0 3.8 0.094 12.6 2.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain FYVE_2 PF02318.11 EGO30806.1 - 0.03 14.2 1.0 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_UBOX PF13445.1 EGO30806.1 - 0.3 10.8 3.7 1.3 8.7 2.1 2.5 2 1 1 3 3 3 0 RING-type zinc-finger DUF1272 PF06906.6 EGO30806.1 - 0.5 10.2 7.7 1.3 8.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) RRN7 PF11781.3 EGO30806.1 - 0.71 9.4 8.4 5.3 6.6 0.0 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 PHD PF00628.24 EGO30806.1 - 1 9.1 12.7 0.15 11.7 2.1 2.8 3 0 0 3 3 3 0 PHD-finger DZR PF12773.2 EGO30806.1 - 2.5 8.0 8.1 2.2 8.1 0.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon RINGv PF12906.2 EGO30806.1 - 4.2 7.4 9.0 1.8 8.6 1.5 2.5 2 1 0 2 2 2 0 RING-variant domain Peptidase_C48 PF02902.14 EGO30807.1 - 6.1e-31 107.7 0.7 1.9e-28 99.5 0.5 2.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ELO PF01151.13 EGO30810.1 - 1.3e-59 201.5 23.5 1.5e-59 201.3 16.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3245 PF11595.3 EGO30812.1 - 0.45 10.7 8.0 0.82 9.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) zf-Di19 PF05605.7 EGO30813.1 - 0.036 14.1 0.6 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Hormone_recep PF00104.25 EGO30815.1 - 0.027 13.6 0.1 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Tet_JBP PF12851.2 EGO30816.1 - 0.036 13.3 0.1 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily LRR19-TM PF15176.1 EGO30816.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF775 PF05603.7 EGO30818.1 - 0.0054 16.2 0.1 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF775) Helicase_C PF00271.26 EGO30819.1 - 2.3e-14 53.0 0.0 6.7e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO30819.1 - 0.078 12.4 0.1 0.28 10.6 0.0 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase Mito_carr PF00153.22 EGO30820.1 - 9e-66 217.6 0.9 1.3e-23 82.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EGO30820.1 - 1.8e-16 58.0 4.9 2.1e-05 23.4 0.0 6.4 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EGO30820.1 - 1.4e-15 57.1 1.6 1.4e-05 25.1 0.1 4.7 3 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EGO30820.1 - 1.1e-14 52.8 5.1 0.00059 19.4 0.1 6.0 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.1 EGO30820.1 - 5e-12 45.2 2.0 0.00027 20.5 0.0 5.5 4 1 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO30820.1 - 2.8e-06 26.4 5.7 0.0036 16.5 0.0 4.3 5 0 0 5 5 5 2 EF hand PP1_inhibitor PF05361.7 EGO30827.1 - 0.0099 15.5 1.0 0.015 14.9 0.7 1.3 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor SUN PF03856.8 EGO30829.1 - 0.0082 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Retrotrans_gag PF03732.12 EGO30832.1 - 3.6e-07 30.1 1.0 1.3e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein Sigma70_r1_2 PF00140.15 EGO30832.1 - 0.0057 16.3 0.5 0.0092 15.6 0.4 1.3 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 WD40 PF00400.27 EGO30833.1 - 5e-31 105.4 12.8 2.8e-12 46.0 0.5 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EGO30833.1 - 0.00056 18.1 0.2 0.22 9.6 0.0 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGO30833.1 - 0.032 12.5 0.0 0.044 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nop14 PF04147.7 EGO30834.1 - 0.41 8.5 10.4 0.47 8.3 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.17 EGO30836.1 - 4.5e-57 191.9 0.2 5.3e-57 191.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO30836.1 - 4e-19 69.2 0.1 9e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGO30836.1 - 2.1e-13 49.8 0.0 2.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO30836.1 - 4e-08 32.6 0.1 4.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO30836.1 - 2.1e-07 30.8 0.0 4e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO30836.1 - 6.8e-07 28.8 0.0 1.2e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 EGO30836.1 - 0.00019 20.5 0.2 0.048 12.6 0.0 2.2 2 0 0 2 2 2 2 Septin ATP_bind_1 PF03029.12 EGO30836.1 - 0.0004 20.0 0.5 0.021 14.3 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EGO30836.1 - 0.00043 19.7 0.1 0.09 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGO30836.1 - 0.00055 20.0 0.0 0.00094 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO30836.1 - 0.0012 18.0 0.1 0.0025 17.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EGO30836.1 - 0.0046 16.4 0.0 0.018 14.4 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EGO30836.1 - 0.0054 16.3 0.3 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 EGO30836.1 - 0.0061 15.8 0.0 0.0094 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EGO30836.1 - 0.0077 15.9 0.4 0.014 15.1 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 EGO30836.1 - 0.0078 15.9 0.1 0.04 13.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EGO30836.1 - 0.0089 15.5 0.1 0.018 14.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EGO30836.1 - 0.0099 15.8 0.1 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EGO30836.1 - 0.018 14.7 0.1 0.044 13.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EGO30836.1 - 0.019 14.6 0.1 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 EGO30836.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EGO30836.1 - 0.089 12.0 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EGO30836.1 - 0.11 12.4 0.1 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGO30836.1 - 0.19 12.0 1.0 0.41 10.9 0.7 1.9 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.6 EGO30837.1 - 8.3e-28 97.5 20.9 1.1e-27 97.1 14.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 EGO30837.1 - 0.014 15.1 18.0 0.049 13.3 1.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2288 PF10052.4 EGO30837.1 - 0.1 12.3 1.1 0.41 10.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2288) DNA_methylase PF00145.12 EGO30837.1 - 0.14 11.2 2.3 0.16 11.0 1.6 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF1664 PF07889.7 EGO30837.1 - 0.72 9.6 6.8 0.59 9.9 1.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EGO30837.1 - 0.86 9.9 13.3 0.37 11.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 EGO30837.1 - 1 9.7 13.0 3.2 8.1 2.9 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.5 EGO30837.1 - 1.1 9.3 11.0 4.4 7.4 1.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EGO30837.1 - 1.2 8.7 20.2 1.2 8.7 9.5 2.0 1 1 1 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EGO30837.1 - 2.7 5.7 8.9 1.4 6.7 4.8 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4094 PF13334.1 EGO30837.1 - 3 8.2 10.3 2.2 8.7 1.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) ARF7EP_C PF14949.1 EGO30837.1 - 3.7 8.0 6.5 0.85 10.0 0.7 2.3 1 1 1 2 2 2 0 ARF7 effector protein C-terminus Frigida PF07899.6 EGO30838.1 - 0.014 14.1 0.9 0.023 13.4 0.6 1.3 1 0 0 1 1 1 0 Frigida-like protein DivIC PF04977.10 EGO30838.1 - 6.5 6.3 9.1 0.27 10.7 2.1 1.9 2 0 0 2 2 2 0 Septum formation initiator DDE_1 PF03184.14 EGO30839.1 - 1e-41 142.5 0.2 1.3e-41 142.1 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EGO30839.1 - 0.00011 21.9 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EGO30839.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease PAT1 PF09770.4 EGO30840.1 - 0.43 8.7 6.8 0.58 8.3 4.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCHC PF00098.18 EGO30841.1 - 1.3e-06 28.0 4.8 1.3e-06 28.0 3.3 2.5 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO30841.1 - 1.5e-06 28.2 0.2 7e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Herpes_UL55 PF04537.7 EGO30841.1 - 0.023 14.0 0.3 0.06 12.7 0.1 1.7 2 0 0 2 2 2 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO30841.1 - 0.053 13.2 3.5 0.19 11.4 2.4 1.9 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.24 EGO30842.1 - 0.0037 16.7 0.1 0.0086 15.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO30842.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PPTA PF01239.17 EGO30844.1 - 1.9 7.9 3.9 5.4 6.5 0.7 2.2 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Astro_capsid PF03115.9 EGO30848.1 - 0.066 11.4 1.1 0.079 11.2 0.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DDE_Tnp_4 PF13359.1 EGO30850.1 - 2.6e-06 27.1 0.0 3.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_DsbA PF11126.3 EGO30850.1 - 0.069 13.2 0.6 0.2 11.7 0.4 1.8 1 1 0 1 1 1 0 Transcriptional regulator DsbA SNF2_N PF00176.18 EGO30851.1 - 2.4e-64 216.9 1.0 3.7e-64 216.3 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EGO30851.1 - 3.1e-24 85.3 0.1 6.5e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EGO30851.1 - 1.2e-14 53.8 0.0 5.9e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 EGO30851.1 - 1e-05 24.9 7.7 0.0015 17.8 0.1 3.0 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain DEAD PF00270.24 EGO30851.1 - 4.9e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.19 EGO30851.1 - 0.0022 17.6 12.3 0.029 14.0 0.5 3.8 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain RVT_2 PF07727.9 EGO30853.1 - 0.00011 21.2 0.2 0.00023 20.2 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.14 EGO30854.1 - 0.1 12.1 0.3 0.2 11.2 0.2 1.4 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Cortex-I_coil PF09304.5 EGO30861.1 - 0.058 13.4 8.3 0.18 11.8 0.6 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil ACT_4 PF13291.1 EGO30861.1 - 0.12 12.7 0.5 4.4 7.6 0.1 2.5 2 0 0 2 2 2 0 ACT domain Prefoldin_2 PF01920.15 EGO30861.1 - 0.54 10.0 10.3 0.66 9.7 1.8 2.6 2 1 0 2 2 2 0 Prefoldin subunit DASH_Hsk3 PF08227.6 EGO30861.1 - 0.58 10.3 4.3 7 6.9 0.6 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Prefoldin PF02996.12 EGO30861.1 - 0.93 9.1 7.7 0.34 10.5 1.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit MMR_HSR1 PF01926.18 EGO30862.1 - 1.6e-16 60.3 0.0 9.5e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO30862.1 - 1.7e-05 24.1 0.1 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGO30862.1 - 0.00016 20.8 0.0 0.0003 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGO30862.1 - 0.0053 15.8 0.1 0.013 14.5 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EGO30862.1 - 0.0079 16.0 0.7 0.034 13.9 0.4 2.0 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 EGO30862.1 - 0.022 15.2 0.9 0.047 14.1 0.1 2.0 2 0 0 2 2 2 0 Miro-like protein zf-CCHC PF00098.18 EGO30865.1 - 2e-07 30.5 2.4 3.8e-07 29.7 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO30865.1 - 1.2 8.8 6.5 2.2 8.0 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C48 PF02902.14 EGO30868.1 - 0.0028 17.3 3.6 0.0054 16.3 2.5 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RPAP3_C PF13877.1 EGO30868.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 NTF2 PF02136.15 EGO30869.1 - 7.3e-13 48.9 0.0 2.1e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGO30869.1 - 2.2e-08 34.0 0.0 2.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 zf-CCHC PF00098.18 EGO30870.1 - 4.4e-06 26.3 3.3 9.5e-06 25.3 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL55 PF04537.7 EGO30870.1 - 0.025 13.9 0.4 0.036 13.4 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL55 protein zf-CCHC_3 PF13917.1 EGO30870.1 - 0.18 11.5 5.0 0.34 10.6 3.5 1.4 1 0 0 1 1 1 0 Zinc knuckle CIAPIN1 PF05093.8 EGO30876.1 - 0.072 13.1 0.2 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Tox-ODYAM1 PF15642.1 EGO30877.1 - 0.00012 20.8 0.9 0.00014 20.6 0.7 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus DUF1664 PF07889.7 EGO30877.1 - 0.1 12.4 0.6 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF148 PF02520.12 EGO30879.1 - 0.042 13.6 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 KH_1 PF00013.24 EGO30882.1 - 2.5e-39 132.6 12.9 9.3e-16 57.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGO30882.1 - 9.3e-27 92.1 11.1 9.2e-10 37.9 0.8 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGO30882.1 - 5.9e-09 35.4 2.0 0.012 15.2 0.1 3.5 3 1 0 3 3 3 3 KH domain KH_2 PF07650.12 EGO30882.1 - 1.4e-08 34.2 5.5 0.054 13.0 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGO30882.1 - 0.00018 21.2 4.0 0.14 12.0 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EGO30882.1 - 0.0013 18.1 1.4 0.24 10.8 0.1 2.8 3 0 0 3 3 3 2 dUTPase PPP4R2 PF09184.6 EGO30883.1 - 0.0058 16.2 11.8 0.0061 16.1 8.2 1.0 1 0 0 1 1 1 1 PPP4R2 Pox_Ag35 PF03286.9 EGO30883.1 - 0.52 9.8 2.5 0.63 9.5 1.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.7 EGO30883.1 - 2 7.5 16.7 2.4 7.3 11.6 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2201_N PF13203.1 EGO30883.1 - 2.1 7.4 4.1 2.3 7.3 2.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Glypican PF01153.14 EGO30883.1 - 2.6 6.5 5.4 2.9 6.3 3.8 1.2 1 0 0 1 1 1 0 Glypican TFIIA PF03153.8 EGO30883.1 - 2.9 7.7 13.5 2.8 7.7 9.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EGO30883.1 - 4.2 5.7 12.1 4.6 5.6 8.4 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 EGO30883.1 - 5.3 6.6 11.5 6.3 6.4 8.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4648 PF15505.1 EGO30885.1 - 0.1 12.8 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) PriCT_2 PF08707.6 EGO30885.1 - 0.11 12.3 0.2 0.23 11.3 0.1 1.7 1 1 1 2 2 2 0 Primase C terminal 2 (PriCT-2) zf-CCHC PF00098.18 EGO30890.1 - 3.4e-09 36.2 2.9 5.9e-09 35.4 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGO30890.1 - 0.12 12.0 1.6 0.27 10.9 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGO30890.1 - 0.2 11.4 5.0 0.12 12.1 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF3375 PF11855.3 EGO30891.1 - 0.16 10.6 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) CCDC74_C PF14917.1 EGO30893.1 - 0.0027 17.7 1.8 0.0053 16.8 1.3 1.5 1 0 0 1 1 1 1 Coiled coil protein 74, C terminal DivIVA PF05103.8 EGO30893.1 - 0.081 12.9 4.1 0.17 11.9 2.8 1.6 1 0 0 1 1 1 0 DivIVA protein IncA PF04156.9 EGO30893.1 - 0.18 11.3 2.3 0.33 10.5 1.6 1.4 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 EGO30893.1 - 0.18 10.9 6.3 0.21 10.7 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit M16C_assoc PF08367.6 EGO30893.1 - 1.6 7.5 5.2 2.9 6.6 3.6 1.4 1 0 0 1 1 1 0 Peptidase M16C associated IFP_35_N PF07334.8 EGO30893.1 - 6.6 6.7 7.2 0.68 9.9 1.5 1.9 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MFS_1 PF07690.11 EGO30896.1 - 6.3e-39 133.6 40.8 1.2e-38 132.7 24.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO30896.1 - 1.1e-11 43.7 7.1 1.9e-11 42.8 1.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO30896.1 - 4.4e-11 42.0 9.3 4.4e-11 42.0 6.5 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter WD40 PF00400.27 EGO30897.1 - 5.5e-11 41.9 0.9 0.00027 20.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 EGO30897.1 - 0.0036 17.0 0.0 31 4.2 0.0 4.4 4 1 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A Peptidase_M41 PF01434.13 EGO30899.1 - 5.3e-71 238.4 0.0 7.3e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGO30899.1 - 9.8e-26 90.5 0.0 1.8e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 EGO30900.1 - 6.4e-27 94.1 28.1 6.1e-26 90.9 20.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EGO30901.1 - 2.6e-27 95.4 36.4 3.7e-27 94.9 23.7 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2762 PF10960.3 EGO30901.1 - 0.18 11.5 1.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) UreD PF01774.12 EGO30903.1 - 3.7e-24 85.3 0.0 7.5e-24 84.3 0.0 1.4 1 1 0 1 1 1 1 UreD urease accessory protein Cation_efflux PF01545.16 EGO30903.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Cation efflux family NRDE-2 PF08424.5 EGO30904.1 - 9.5e-52 175.8 3.3 2e-51 174.8 2.3 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EGO30904.1 - 4.9e-06 26.7 13.3 1.5 9.6 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat UPF0113 PF03657.8 EGO30905.1 - 2.5e-11 43.4 0.0 3.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Sec39 PF08314.6 EGO30907.1 - 2.9e-67 227.1 0.0 5.1e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Cgr1 PF03879.9 EGO30908.1 - 3e-11 43.4 19.1 4.7e-11 42.8 13.2 1.3 1 0 0 1 1 1 1 Cgr1 family Neur_chan_memb PF02932.11 EGO30908.1 - 4.1 7.2 5.8 6.3 6.6 3.8 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.9 EGO30908.1 - 6.5 6.6 8.6 8.3 6.3 6.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pep3_Vps18 PF05131.9 EGO30909.1 - 5.8e-43 145.8 0.0 1.3e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGO30909.1 - 7e-08 32.1 0.2 0.0027 17.3 0.0 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 EGO30909.1 - 3.3e-05 24.0 0.1 0.0001 22.4 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EGO30909.1 - 4e-05 23.3 3.4 0.00016 21.4 1.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGO30909.1 - 5.8e-05 22.7 2.9 7.7e-05 22.3 0.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO30909.1 - 0.0046 16.6 0.5 0.11 12.2 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO30909.1 - 0.0063 16.5 3.2 0.012 15.5 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.7 EGO30909.1 - 0.01 15.6 0.2 0.08 12.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_UBOX PF13445.1 EGO30909.1 - 0.034 13.8 0.7 0.18 11.5 0.3 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EGO30909.1 - 0.41 10.3 6.8 0.038 13.6 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EGO30909.1 - 0.78 9.8 5.5 12 6.1 0.4 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat His_Phos_1 PF00300.17 EGO30910.1 - 3.5e-28 98.7 0.0 4.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.22 EGO30911.1 - 5.5e-29 99.7 9.1 5.6e-13 48.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.7 EGO30912.1 - 2.9e-11 42.8 1.0 5.5e-11 41.9 0.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Adeno_PIX PF03955.9 EGO30912.1 - 0.11 13.0 0.1 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TRAPPC-Trs85 PF12739.2 EGO30913.1 - 8.8e-32 110.2 2.8 2e-27 95.9 0.1 2.2 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 EGO30913.1 - 2e-06 25.4 0.1 2.9e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF4355 PF14265.1 EGO30914.1 - 0.042 13.8 5.1 0.062 13.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) EVC2_like PF12297.3 EGO30914.1 - 0.067 11.8 1.0 0.084 11.4 0.7 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein WW PF00397.21 EGO30914.1 - 0.072 12.9 1.1 0.15 11.9 0.8 1.6 1 0 0 1 1 1 0 WW domain Dehydrin PF00257.14 EGO30914.1 - 0.12 12.7 1.9 0.18 12.1 0.9 1.5 1 1 0 1 1 1 0 Dehydrin MBD PF01429.14 EGO30915.1 - 0.0039 16.6 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain LCCL PF03815.14 EGO30916.1 - 4.3e-16 58.6 0.1 6.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.9 EGO30919.1 - 1.1e-18 67.4 0.0 6.8e-17 61.6 0.0 2.3 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) VIT1 PF01988.14 EGO30919.1 - 0.25 10.7 3.2 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 VIT family adh_short PF00106.20 EGO30920.1 - 1e-26 93.8 0.8 1.5e-26 93.2 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO30920.1 - 6e-18 65.4 0.0 1.7e-17 63.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO30920.1 - 1.6e-09 37.7 0.8 3.8e-09 36.4 0.5 1.7 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EGO30920.1 - 0.0071 16.7 0.1 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EGO30920.1 - 0.01 15.8 0.2 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding LMWPc PF01451.16 EGO30921.1 - 5.5e-34 117.4 0.0 6.1e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Aldedh PF00171.17 EGO30922.1 - 9.4e-125 416.5 0.1 1.1e-124 416.2 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO30922.1 - 0.0051 15.5 0.0 0.0071 15.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) GDI PF00996.13 EGO30924.1 - 2.4e-207 688.5 0.0 2.7e-207 688.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rav1p_C PF12234.3 EGO30925.1 - 4.5e-184 613.1 0.0 6.5e-184 612.6 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Kinesin PF00225.18 EGO30926.1 - 1.3e-82 277.2 0.0 2.2e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Pox_RNA_Pol_19 PF05320.7 EGO30926.1 - 0.099 12.3 1.5 0.23 11.1 1.1 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nop14 PF04147.7 EGO30926.1 - 0.71 7.7 8.8 1.2 6.9 6.1 1.3 1 0 0 1 1 1 0 Nop14-like family Fasciclin PF02469.17 EGO30927.1 - 2.7e-69 231.0 0.0 9.2e-16 58.0 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.22 EGO30927.1 - 6.9e-69 227.6 5.3 1.1e-22 79.5 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF619 PF04768.8 EGO30928.1 - 5.5e-36 123.5 0.1 1.2e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) F-box PF00646.28 EGO30929.1 - 2.8e-08 33.2 1.2 9.8e-08 31.4 0.8 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO30929.1 - 0.0014 18.2 0.4 0.004 16.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EGO30930.1 - 6.1e-14 51.7 0.0 8.1e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30930.1 - 7.2e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO30930.1 - 0.0049 15.9 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO30930.1 - 0.0051 16.5 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RE_Bsp6I PF09504.5 EGO30931.1 - 0.03 13.7 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Bsp6I restriction endonuclease UQ_con PF00179.21 EGO30932.1 - 6.3e-20 71.0 0.0 1.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4537 PF15057.1 EGO30932.1 - 0.082 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) SKN1 PF03935.10 EGO30933.1 - 7.9e-189 627.9 4.5 9.2e-189 627.7 3.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF2106 PF09879.4 EGO30934.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) p450 PF00067.17 EGO30935.1 - 4.5e-39 134.2 0.1 1.6e-25 89.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RdRP PF05183.7 EGO30936.1 - 2.3e-132 442.6 0.0 3e-132 442.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Prefoldin_2 PF01920.15 EGO30937.1 - 3.4e-23 81.4 12.1 4.4e-23 81.0 8.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGO30937.1 - 0.0036 17.0 3.8 0.0048 16.6 2.4 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EGO30937.1 - 0.0042 16.7 7.2 0.037 13.6 1.9 2.3 2 0 0 2 2 2 1 Prefoldin subunit YgaB PF14182.1 EGO30937.1 - 0.0079 16.4 6.0 0.0079 16.4 4.1 2.5 2 1 0 2 2 2 1 YgaB-like protein MCPsignal PF00015.16 EGO30937.1 - 0.021 14.3 5.9 0.16 11.5 1.2 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlxA PF14282.1 EGO30937.1 - 0.022 14.7 4.5 0.022 14.7 3.1 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF4160 PF13711.1 EGO30937.1 - 0.028 14.2 1.0 0.049 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) NPV_P10 PF05531.7 EGO30937.1 - 0.031 14.5 4.9 0.99 9.6 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EGO30937.1 - 0.032 12.8 10.1 0.043 12.4 7.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGO30937.1 - 0.036 13.6 14.1 0.63 9.6 9.8 2.0 1 1 0 1 1 1 0 IncA protein DUF607 PF04678.8 EGO30937.1 - 0.039 13.8 4.6 0.063 13.2 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Occludin_ELL PF07303.8 EGO30937.1 - 0.052 14.2 5.7 0.37 11.5 0.2 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF3114 PF11311.3 EGO30937.1 - 0.062 12.6 0.5 0.063 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) DUF4201 PF13870.1 EGO30937.1 - 0.067 12.6 9.1 0.32 10.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FliD_C PF07195.7 EGO30937.1 - 0.076 12.2 4.8 0.039 13.2 1.7 1.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4407 PF14362.1 EGO30937.1 - 0.13 11.2 7.8 0.16 10.9 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) End3 PF12761.2 EGO30937.1 - 0.13 11.8 7.6 0.21 11.1 5.3 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Rho_Binding PF08912.6 EGO30937.1 - 0.14 12.4 11.8 1.6 9.0 0.9 2.3 2 0 0 2 2 2 0 Rho Binding CENP-F_leu_zip PF10473.4 EGO30937.1 - 0.16 11.7 13.3 0.4 10.5 0.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ada3 PF10198.4 EGO30937.1 - 0.17 11.6 5.2 0.77 9.5 0.6 2.5 2 1 1 3 3 3 0 Histone acetyltransferases subunit 3 Atg14 PF10186.4 EGO30937.1 - 0.17 10.8 7.2 0.21 10.4 5.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ALIX_LYPXL_bnd PF13949.1 EGO30937.1 - 0.17 10.8 8.1 0.79 8.6 1.5 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV CO_dh PF02552.11 EGO30937.1 - 0.18 11.3 1.5 0.24 10.9 1.0 1.3 1 1 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF1515 PF07439.6 EGO30937.1 - 0.18 11.6 2.0 2.1 8.1 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) HrpB7 PF09486.5 EGO30937.1 - 0.21 11.5 4.3 1.4 8.8 0.6 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spc24 PF08286.6 EGO30937.1 - 0.33 10.6 12.0 1.3 8.7 1.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FANCI_S3 PF14677.1 EGO30937.1 - 0.42 9.9 2.9 0.18 11.1 0.4 1.6 2 0 0 2 2 2 0 FANCI solenoid 3 ERp29 PF07749.7 EGO30937.1 - 0.59 10.8 5.0 0.7 10.5 0.8 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Hrs_helical PF12210.3 EGO30937.1 - 0.95 9.7 5.0 0.3 11.3 0.3 2.1 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GAS PF13851.1 EGO30937.1 - 1.1 8.4 14.5 6.2 5.9 10.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 EGO30937.1 - 1.1 9.0 6.1 1.7 8.4 1.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 EGO30937.1 - 1.2 8.9 12.8 0.34 10.8 2.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 EGO30937.1 - 1.3 8.8 13.6 3.8 7.3 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF972 PF06156.8 EGO30937.1 - 1.3 9.3 11.6 42 4.5 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 EGO30937.1 - 1.4 8.6 8.0 3.4 7.4 1.3 2.1 2 0 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 EGO30937.1 - 1.7 8.7 7.1 1.1 9.4 1.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.1 EGO30937.1 - 1.9 8.6 12.2 0.85 9.7 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Macoilin PF09726.4 EGO30937.1 - 2 6.6 9.5 2.6 6.2 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Cluap1 PF10234.4 EGO30937.1 - 2.3 7.3 12.2 28 3.7 8.4 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF904 PF06005.7 EGO30937.1 - 2.7 8.3 14.3 0.049 13.9 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) AAA_13 PF13166.1 EGO30937.1 - 3.1 6.1 11.2 4.7 5.5 7.8 1.3 1 1 0 1 1 1 0 AAA domain CASP_C PF08172.7 EGO30937.1 - 3.2 6.7 8.2 6.5 5.6 1.2 2.0 2 0 0 2 2 2 0 CASP C terminal DUF919 PF06034.6 EGO30937.1 - 3.2 7.4 6.6 2.2 7.9 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) IFT57 PF10498.4 EGO30937.1 - 3.2 6.3 10.6 1.9 7.1 2.7 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Mnd1 PF03962.10 EGO30937.1 - 3.3 7.3 13.0 32 4.1 9.0 1.9 1 1 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 EGO30937.1 - 3.7 8.0 10.0 3 8.3 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.8 EGO30937.1 - 4.5 7.1 11.4 2.2 8.1 4.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.1 EGO30937.1 - 4.8 7.1 8.8 4.3 7.3 1.8 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 APG6 PF04111.7 EGO30937.1 - 4.9 6.1 15.0 41 3.0 10.4 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Enkurin PF13864.1 EGO30937.1 - 5.3 7.3 11.1 0.73 10.0 0.3 2.6 2 1 0 2 2 2 0 Calmodulin-binding CDC37_N PF03234.9 EGO30937.1 - 5.5 7.2 9.3 7.6 6.8 2.2 1.9 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding AAA_23 PF13476.1 EGO30937.1 - 8.7 6.6 14.1 15 5.8 9.8 1.4 1 1 0 1 1 1 0 AAA domain G_glu_transpept PF01019.16 EGO30938.1 - 1.4e-146 489.0 0.0 1.5e-146 488.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PP2C PF00481.16 EGO30939.1 - 2.5e-40 138.5 0.0 1.2e-37 129.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGO30939.1 - 0.0019 17.6 0.0 0.0047 16.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C His_Phos_2 PF00328.17 EGO30940.1 - 1.1e-41 143.3 0.0 1.3e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Git3 PF11710.3 EGO30941.1 - 3.1e-08 33.4 15.4 2.6e-07 30.4 10.7 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EGO30941.1 - 7.7e-07 28.4 4.1 1.2e-06 27.8 2.1 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.6 EGO30941.1 - 0.02 13.7 2.1 0.061 12.1 1.4 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Snf7 PF03357.16 EGO30942.1 - 9.7e-30 103.1 12.7 1.2e-29 102.8 8.8 1.1 1 0 0 1 1 1 1 Snf7 DUF2400 PF09674.5 EGO30942.1 - 0.018 14.7 0.4 0.028 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) HAUS2 PF15003.1 EGO30942.1 - 0.059 12.4 2.5 0.077 12.0 1.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF2481 PF10654.4 EGO30942.1 - 0.51 10.0 3.6 0.41 10.3 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2481) Pro_isomerase PF00160.16 EGO30943.1 - 2.4e-43 148.0 0.0 3.7e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-Nse PF11789.3 EGO30943.1 - 0.0054 16.2 0.1 0.035 13.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EGO30943.1 - 0.032 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain PPR_2 PF13041.1 EGO30945.1 - 9.7e-51 169.5 0.4 9.6e-10 38.2 0.0 9.1 7 2 4 11 11 11 8 PPR repeat family PPR_3 PF13812.1 EGO30945.1 - 1.1e-32 109.5 5.0 3.4e-05 23.8 0.0 11.9 13 1 0 13 13 13 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGO30945.1 - 7.2e-24 82.9 0.3 0.013 14.9 0.0 10.0 10 0 0 10 10 10 6 PPR repeat PPR PF01535.15 EGO30945.1 - 2.9e-22 77.0 10.9 0.0065 16.3 0.0 11.3 13 0 0 13 13 13 5 PPR repeat TPR_14 PF13428.1 EGO30945.1 - 2.3e-06 27.7 2.6 1.5 9.6 0.0 7.1 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO30945.1 - 0.00049 20.6 0.2 0.095 13.4 0.0 4.6 6 1 0 6 6 6 1 Tetratricopeptide repeat RPM2 PF08579.6 EGO30945.1 - 0.0066 16.5 0.4 18 5.4 0.0 4.9 4 2 2 6 6 6 0 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EGO30945.1 - 0.075 11.8 0.1 30 3.3 0.0 3.9 2 1 3 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway VanW PF04294.8 EGO30945.1 - 0.089 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 VanW like protein Sugar_tr PF00083.19 EGO30946.1 - 4e-99 332.2 15.4 4.5e-99 332.0 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO30946.1 - 3.8e-28 98.2 45.3 5.8e-27 94.3 16.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.24 EGO30947.1 - 2.3e-19 69.5 0.1 7.4e-19 67.8 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO30947.1 - 3.5e-06 26.7 0.0 7.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO30947.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGO30947.1 - 0.079 12.0 1.4 0.51 9.3 0.0 2.6 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF4203 PF13886.1 EGO30948.1 - 1.6e-31 109.4 33.9 2.5e-30 105.5 15.6 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4203) Co_AT_N PF12557.3 EGO30948.1 - 3.5 7.6 7.6 4.4 7.3 0.7 2.9 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal LAG1-DNAbind PF09271.6 EGO30950.1 - 8.2e-26 91.1 0.0 3.7e-24 85.8 0.0 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EGO30950.1 - 1.5e-24 86.5 0.0 3.5e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.16 EGO30951.1 - 4.6e-156 518.7 0.2 6.4e-156 518.3 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGO30951.1 - 8.3e-28 96.2 0.0 3e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGO30951.1 - 3.3e-05 22.8 0.2 8.7e-05 21.5 0.2 1.7 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EGO30951.1 - 0.0019 17.1 0.1 0.0066 15.3 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.14 EGO30951.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family U32 Gly_transf_sug PF04488.10 EGO30952.1 - 1.3e-06 28.7 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGO30952.1 - 0.0044 16.2 0.4 0.0068 15.6 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EGO30953.1 - 1e-05 25.8 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGO30953.1 - 0.025 13.7 0.3 0.047 12.8 0.2 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Transgly_assoc PF04226.8 EGO30954.1 - 0.77 9.8 5.6 2.4 8.2 0.9 3.0 2 0 0 2 2 2 0 Transglycosylase associated protein COX6A PF02046.10 EGO30955.1 - 2.4e-28 98.3 0.1 2.6e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa 2-Hacid_dh_C PF02826.14 EGO30956.1 - 1.1e-54 184.2 0.0 2.9e-54 182.9 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PC_rep PF01851.17 EGO30956.1 - 4.7e-29 98.9 28.2 7.1e-09 35.4 0.0 9.3 9 0 0 9 9 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGO30956.1 - 2.1e-15 56.7 2.6 7.6e-11 42.1 0.0 4.8 3 1 1 4 4 4 2 HEAT repeats 2-Hacid_dh PF00389.25 EGO30956.1 - 1.5e-09 37.4 0.0 3.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HEAT PF02985.17 EGO30956.1 - 1.7e-07 30.7 0.2 2.1 8.6 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EGO30956.1 - 6.1e-07 29.7 0.4 0.02 15.3 0.0 4.9 4 0 0 4 4 3 2 HEAT-like repeat NAD_binding_2 PF03446.10 EGO30956.1 - 0.00021 21.1 0.1 0.00076 19.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGO30956.1 - 0.0091 15.3 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EGO30956.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGO30956.1 - 0.09 12.3 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Adaptin_N PF01602.15 EGO30956.1 - 0.096 10.9 0.0 0.51 8.5 0.0 2.1 2 1 0 2 2 2 0 Adaptin N terminal region Arm PF00514.18 EGO30957.1 - 4.8e-91 295.8 12.4 1.1e-12 47.3 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EGO30957.1 - 1e-22 79.9 3.1 1.7e-08 34.6 0.0 5.5 4 1 2 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.1 EGO30957.1 - 2.2e-22 79.1 0.0 1.6e-07 31.4 0.0 5.4 1 1 4 5 5 5 5 HEAT repeats IBB PF01749.15 EGO30957.1 - 5.6e-20 71.2 5.3 9e-20 70.6 3.7 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EGO30957.1 - 3.3e-16 57.8 0.6 9.3e-05 22.1 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.8 EGO30957.1 - 1.7e-07 30.5 0.0 0.069 12.2 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EGO30957.1 - 1.6e-06 26.7 0.0 0.00024 19.5 0.0 2.9 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.1 EGO30957.1 - 7.4e-05 22.6 2.6 0.087 12.7 0.0 4.4 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EGO30957.1 - 0.0035 17.6 1.6 0.57 10.8 0.0 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EGO30957.1 - 0.004 17.0 0.2 2.5 8.0 0.0 4.2 3 3 3 6 6 6 2 V-ATPase subunit H Mo25 PF08569.6 EGO30957.1 - 0.056 12.4 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Mo25-like Proteasom_PSMB PF10508.4 EGO30957.1 - 0.1 10.8 0.0 0.58 8.3 0.0 2.0 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit LSM PF01423.17 EGO30958.1 - 3.3e-21 74.5 0.0 3.8e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain UPF0565 PF10561.4 EGO30958.1 - 0.032 13.1 0.0 0.036 12.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Ribosomal_S16 PF00886.14 EGO30959.1 - 3.5e-20 71.4 0.0 4.7e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.14 EGO30960.1 - 7.1e-18 64.0 0.0 1.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.1 EGO30960.1 - 1.8e-14 53.7 0.1 5.1e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO30960.1 - 5.1e-13 48.1 0.1 2.4e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGO30960.1 - 8.1e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO30960.1 - 1.5e-12 47.2 0.0 4.8e-10 39.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO30960.1 - 6.7e-11 41.3 0.0 3.7e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat CoA_binding PF02629.14 EGO30961.1 - 3.3e-27 94.8 1.6 5.9e-27 94.0 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGO30961.1 - 9.2e-25 87.0 0.0 1.5e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGO30961.1 - 4e-08 32.9 0.0 1.3e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGO30961.1 - 8.4e-06 25.9 0.0 5.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EGO30961.1 - 0.002 18.6 0.0 0.0054 17.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NTPase_1 PF03266.10 EGO30961.1 - 0.1 12.3 0.1 0.62 9.7 0.1 2.2 2 1 1 3 3 3 0 NTPase Xpo1 PF08389.7 EGO30962.1 - 8.2e-23 80.9 0.1 6.3e-21 74.8 0.0 3.4 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EGO30962.1 - 7.1e-07 29.0 0.1 9.1e-05 22.3 0.0 3.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 EGO30962.1 - 0.028 14.4 0.2 29 5.0 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Septin PF00735.13 EGO30963.1 - 2.9e-122 407.1 0.0 2.9e-122 407.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGO30963.1 - 1.6e-07 31.2 0.0 3.4e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO30963.1 - 3e-05 23.2 0.2 0.00019 20.6 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGO30963.1 - 0.00014 22.1 1.5 0.038 14.2 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AAA_22 PF13401.1 EGO30963.1 - 0.00057 20.0 0.0 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EGO30963.1 - 0.00079 18.9 1.6 0.045 13.1 0.0 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO30963.1 - 0.0012 18.7 3.2 0.39 10.5 0.0 3.1 2 1 0 3 3 3 2 Dynamin family AIG1 PF04548.11 EGO30963.1 - 0.0099 15.0 0.2 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Ras PF00071.17 EGO30963.1 - 0.01 15.2 0.0 0.1 11.9 0.0 2.5 2 1 0 2 2 2 0 Ras family AAA_10 PF12846.2 EGO30963.1 - 0.013 14.9 0.1 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EGO30963.1 - 0.024 14.6 0.2 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EGO30963.1 - 0.028 13.9 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EGO30963.1 - 0.032 14.7 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EGO30963.1 - 0.034 13.7 0.1 3.6 7.0 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.6 EGO30963.1 - 0.067 12.9 2.7 0.081 12.7 1.0 1.8 1 1 0 1 1 1 0 Streptococcal surface antigen repeat MobB PF03205.9 EGO30963.1 - 0.079 12.6 0.1 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EGO30963.1 - 0.16 11.5 1.5 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain CN_hydrolase PF00795.17 EGO30965.1 - 7.7e-35 119.9 0.0 9.6e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.4 EGO30966.1 - 6.6e-26 90.8 0.0 9.3e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.8 EGO30967.1 - 3.2e-44 150.2 0.0 3.5e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 EGO30967.1 - 0.0021 17.6 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c7 PHD PF00628.24 EGO30967.1 - 0.034 13.8 2.1 0.053 13.2 0.3 2.0 2 0 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 EGO30967.1 - 6.5 6.6 8.1 4.1 7.2 3.7 2.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain IQ PF00612.22 EGO30969.1 - 0.03 13.9 2.5 0.063 12.9 1.7 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif EutC PF05985.6 EGO30969.1 - 0.083 11.9 0.3 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) DUF1248 PF06852.7 EGO30969.1 - 0.13 11.5 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Pkinase PF00069.20 EGO30970.1 - 1.8e-69 233.8 0.0 2.5e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO30970.1 - 3.4e-46 157.4 0.0 5.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO30970.1 - 1.5e-08 33.9 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGO30970.1 - 0.00038 19.5 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGO30970.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGO30970.1 - 0.25 10.6 0.5 12 5.2 0.3 2.3 2 0 0 2 2 2 0 RIO1 family CLTH PF10607.4 EGO30971.1 - 2.3e-35 121.3 0.1 3.3e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGO30971.1 - 2.4e-11 42.9 0.2 4.8e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 LisH ATP_bind_2 PF03668.10 EGO30971.1 - 0.21 10.6 1.1 2.9 6.9 0.1 2.0 1 1 1 2 2 2 0 P-loop ATPase protein family BATS PF06968.8 EGO30972.1 - 3.2e-28 97.4 0.0 7.8e-28 96.1 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGO30972.1 - 3.6e-14 53.2 0.0 6.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily HABP4_PAI-RBP1 PF04774.10 EGO30973.1 - 0.00094 19.6 10.3 0.00094 19.6 7.1 3.5 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family PepSY_TM_1 PF13172.1 EGO30974.1 - 0.55 10.0 3.1 1.2 8.9 2.1 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix zf-CCHC PF00098.18 EGO30975.1 - 4.5e-08 32.6 1.1 6.8e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO30975.1 - 0.015 14.9 0.4 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO30975.1 - 0.12 12.0 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.17 EGO30976.1 - 8.4e-54 179.1 0.0 7.7e-19 67.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO30976.1 - 7.5e-40 134.7 0.0 8.7e-13 48.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO30976.1 - 9.6e-26 89.4 0.0 1e-08 34.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO30976.1 - 0.0012 18.6 0.0 0.34 10.7 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EGO30976.1 - 0.0013 18.6 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Ribosomal_S27e PF01667.12 EGO30977.1 - 1.6e-29 101.1 3.3 1.9e-29 100.9 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EGO30977.1 - 0.0025 17.6 1.4 0.003 17.3 1.0 1.2 1 0 0 1 1 1 1 IBR domain zf-C3HC4_3 PF13920.1 EGO30977.1 - 2.1 8.0 5.4 7.6 6.2 3.9 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pribosyltran_N PF13793.1 EGO30978.1 - 1.9e-44 150.0 1.6 2.9e-43 146.2 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGO30978.1 - 4.3e-38 130.9 2.7 1.8e-32 112.5 1.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGO30978.1 - 1.9e-13 50.2 1.2 9.2e-12 44.7 0.3 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO30978.1 - 0.00061 19.0 0.4 0.0012 18.1 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SDH_sah PF01972.11 EGO30978.1 - 0.032 12.9 0.1 0.05 12.3 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF848 PF05852.6 EGO30978.1 - 0.092 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) CTDII PF01556.13 EGO30979.1 - 6.9e-30 102.7 1.6 1.4e-21 76.1 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EGO30979.1 - 3.3e-24 84.3 2.4 5.3e-24 83.7 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGO30979.1 - 7.1e-08 32.3 19.5 8.5e-08 32.1 12.3 2.0 2 0 0 2 2 2 1 DnaJ central domain MFS_1 PF07690.11 EGO30980.1 - 2.4e-39 135.0 44.0 6e-39 133.7 30.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO30980.1 - 1.1e-12 47.3 7.7 1.1e-12 47.3 5.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter RVP_2 PF08284.6 EGO30981.1 - 0.017 15.0 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease HEAT PF02985.17 EGO30982.1 - 5.7e-44 144.2 17.0 0.0011 18.8 0.0 13.5 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.1 EGO30982.1 - 4e-32 110.3 8.5 1.5e-08 34.7 0.0 6.7 2 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EGO30982.1 - 6.2e-12 45.7 1.1 0.025 14.9 0.0 7.1 3 3 5 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGO30982.1 - 6.9e-07 29.5 18.5 1.6 9.2 0.0 8.7 7 3 2 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 EGO30982.1 - 1.8e-06 26.6 4.4 0.025 12.8 0.1 4.0 2 2 1 3 3 3 2 Adaptin N terminal region Arm PF00514.18 EGO30982.1 - 6.9e-06 25.6 1.0 0.61 9.9 0.0 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EGO30982.1 - 1.4e-05 25.0 0.1 0.0017 18.2 0.0 3.9 2 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 EGO30982.1 - 0.047 14.1 9.3 0.56 10.8 0.1 6.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Ecm29 PF13001.2 EGO30982.1 - 0.095 11.1 4.5 2.6 6.4 0.1 3.4 3 1 1 4 4 4 0 Proteasome stabiliser PepSY_TM_1 PF13172.1 EGO30983.1 - 7 6.5 7.0 4.8 7.0 3.1 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix BRCA-2_OB1 PF09103.5 EGO30985.1 - 4e-31 107.1 0.0 7.8e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EGO30985.1 - 8.6e-06 25.4 0.1 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BRCA2, helical Taxilin PF09728.4 EGO30986.1 - 1.3e-14 53.9 33.1 8.4e-08 31.6 14.1 2.4 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 EGO30986.1 - 5e-07 29.3 1.3 0.0064 16.1 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like UDPGP PF01704.13 EGO30987.1 - 1.2e-48 165.7 0.0 1.5e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGO30987.1 - 0.0053 16.8 0.1 0.02 15.0 0.0 2.1 2 1 0 2 2 2 1 MobA-like NTP transferase domain Cellulase PF00150.13 EGO30988.1 - 8.7e-14 51.3 0.1 8.7e-14 51.3 0.1 2.0 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Fibrillarin PF01269.12 EGO30988.1 - 0.19 10.6 0.0 5.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Fibrillarin Cellulase PF00150.13 EGO30989.1 - 6.9e-14 51.7 0.5 1.3e-13 50.8 0.4 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M16 PF00675.15 EGO30990.1 - 3.7e-38 130.6 0.1 9.5e-38 129.2 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO30990.1 - 3.9e-32 111.4 0.0 1.6e-31 109.4 0.0 1.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain EF_TS PF00889.14 EGO30991.1 - 8.4e-19 67.7 0.0 2.7e-17 62.8 0.0 2.2 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 EGO30991.1 - 0.00087 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EGO30991.1 - 0.0033 16.9 0.1 0.0078 15.7 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain Med11 PF10280.4 EGO30991.1 - 0.015 15.3 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Mediator complex protein Gar1 PF04410.9 EGO30992.1 - 4.6e-30 104.1 0.1 9.7e-30 103.0 0.1 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Mis14 PF08641.7 EGO30992.1 - 3.1 7.8 7.3 0.5 10.4 1.0 2.3 2 1 0 2 2 2 0 Kinetochore protein Mis14 like Ribonuclease_T2 PF00445.13 EGO30993.1 - 2.3e-42 144.7 0.0 3.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.1 EGO30994.1 - 4.7e-21 74.0 0.0 8.3e-21 73.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain Tic22 PF04278.7 EGO30994.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Tic22-like family PEHE PF15275.1 EGO30995.1 - 1.2e-05 25.7 0.8 1.2e-05 25.7 0.6 2.5 2 1 0 2 2 2 1 PEHE domain SAS4 PF15460.1 EGO30995.1 - 0.00031 20.5 4.4 0.00069 19.4 3.1 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 zf-DHHC PF01529.15 EGO30996.1 - 6.3e-42 142.9 5.5 1.3e-41 141.8 3.8 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Bromodomain PF00439.20 EGO30997.1 - 3e-20 71.9 0.2 3.9e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 Bromodomain SpoVG PF04026.7 EGO30997.1 - 0.086 12.8 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 SpoVG Cyt-b5 PF00173.23 EGO30998.1 - 3e-06 26.9 0.0 1.1e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EGO30998.1 - 0.00022 20.7 11.2 0.00022 20.7 7.7 2.9 3 1 0 3 3 3 1 Fatty acid desaturase CutC PF03932.9 EGO30999.1 - 7.7e-55 185.2 0.0 9.4e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 CutC family F-box-like PF12937.2 EGO31000.1 - 2.3e-08 33.5 1.9 6.1e-08 32.2 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO31000.1 - 6.7e-08 31.9 1.3 1.6e-07 30.7 0.9 1.7 1 0 0 1 1 1 1 F-box domain Glyco_transf_22 PF03901.12 EGO31002.1 - 4.7e-83 279.5 18.5 1.1e-82 278.3 12.8 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4181 PF13789.1 EGO31002.1 - 0.069 13.0 2.7 0.074 12.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Histone PF00125.19 EGO31004.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO31004.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGO31004.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGO31004.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGO31004.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGO31004.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.15 EGO31005.1 - 1.5e-27 95.3 0.0 1.9e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGO31005.1 - 4e-07 30.0 0.1 3.1e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGO31005.1 - 5.3e-06 26.5 0.2 3.1e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGO31005.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGO31005.1 - 0.00021 20.9 0.1 0.00066 19.3 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGO31005.1 - 0.00088 18.8 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EGO31005.1 - 0.0015 18.1 0.1 0.0062 16.0 0.0 2.0 2 1 0 2 2 2 1 Redoxin DUF2847 PF11009.3 EGO31005.1 - 0.037 13.6 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF953 PF06110.6 EGO31005.1 - 0.14 11.5 0.0 0.61 9.5 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) PBP1_TM PF14812.1 EGO31006.1 - 1.5 9.1 6.2 3.3 8.0 4.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pyrophosphatase PF00719.14 EGO31007.1 - 4.2e-54 182.2 0.2 7.2e-54 181.4 0.2 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase Spc97_Spc98 PF04130.8 EGO31008.1 - 6.9e-67 225.9 1.2 9.7e-67 225.4 0.8 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family RabGAP-TBC PF00566.13 EGO31009.1 - 8.9e-32 110.2 0.0 1.4e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nop52 PF05997.7 EGO31010.1 - 1.4e-33 116.1 0.2 1.6e-33 116.0 0.2 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 CART PF06373.6 EGO31011.1 - 0.11 12.4 1.5 0.42 10.6 0.0 2.0 1 1 1 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Phostensin PF13914.1 EGO31012.1 - 0.39 10.8 4.2 0.21 11.7 0.6 2.0 1 1 1 2 2 2 0 Phostensin PP1-binding and SH3-binding region NACHT PF05729.7 EGO31013.1 - 5.8e-05 22.8 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain UQ_con PF00179.21 EGO31014.1 - 4.3e-39 133.1 0.1 5.5e-39 132.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGO31014.1 - 0.0012 18.6 0.4 0.0016 18.2 0.3 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EGO31014.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.1 EGO31014.1 - 0.066 12.9 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B NapB PF03892.9 EGO31014.1 - 0.19 11.4 0.8 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) 2OG-FeII_Oxy PF03171.15 EGO31015.1 - 0.00041 20.5 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PPR_2 PF13041.1 EGO31016.1 - 4.2e-38 129.0 0.1 6e-08 32.5 0.0 7.1 4 2 3 7 7 7 7 PPR repeat family PPR_1 PF12854.2 EGO31016.1 - 4.7e-21 73.9 0.1 6.5e-07 28.7 0.0 6.8 7 1 0 7 7 7 3 PPR repeat PPR PF01535.15 EGO31016.1 - 6e-19 66.6 2.4 2.6e-05 23.8 0.0 7.2 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.1 EGO31016.1 - 9.9e-18 62.8 14.6 0.0025 17.9 0.0 9.1 11 0 0 11 11 11 4 Pentatricopeptide repeat domain TPR_14 PF13428.1 EGO31016.1 - 6.7e-06 26.2 3.2 12 6.8 0.2 6.2 4 2 2 6 6 6 1 Tetratricopeptide repeat ECSIT PF06239.6 EGO31016.1 - 0.00049 19.0 0.1 0.95 8.2 0.0 3.8 4 0 0 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway ELYS PF13934.1 EGO31016.1 - 0.022 14.4 0.7 0.47 10.1 0.0 3.1 4 0 0 4 4 4 0 Nuclear pore complex assembly RPM2 PF08579.6 EGO31016.1 - 0.025 14.6 2.2 9.6 6.3 0.1 4.4 3 2 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_4 PF07721.9 EGO31016.1 - 0.07 13.5 0.7 3.8 8.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Chorismate_bind PF00425.13 EGO31017.1 - 4.6e-63 212.9 0.0 9e-63 211.9 0.0 1.5 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EGO31017.1 - 7.7e-35 120.0 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EGO31017.1 - 3.6e-22 78.8 0.0 1.2e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EGO31017.1 - 2.3e-05 23.9 1.6 0.00011 21.7 1.1 1.9 1 1 0 1 1 1 1 Peptidase C26 AAA-ATPase_like PF09820.4 EGO31017.1 - 0.24 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase HEAT PF02985.17 EGO31018.1 - 4.2e-05 23.2 5.9 0.15 12.1 0.0 4.5 4 0 0 4 4 4 3 HEAT repeat RNase_P_pop3 PF08228.6 EGO31020.1 - 1.5e-14 54.1 0.0 1.4e-10 41.2 0.0 2.7 2 1 0 2 2 2 2 RNase P subunit Pop3 Amidase PF01425.16 EGO31021.1 - 2.4e-96 323.2 0.0 2.9e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Amidase AATase PF07247.7 EGO31022.1 - 0.00033 19.3 0.0 0.00076 18.1 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase TPT PF03151.11 EGO31024.1 - 8e-10 38.5 9.2 8e-10 38.5 6.4 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGO31024.1 - 1.1e-06 28.6 24.7 3.4e-05 23.8 4.4 2.6 2 2 0 2 2 2 2 EamA-like transporter family DUF2910 PF11139.3 EGO31024.1 - 7.9 5.5 17.5 0.73 8.9 6.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) O-FucT PF10250.4 EGO31025.1 - 8.9e-10 38.1 0.0 6.2e-09 35.4 0.0 2.2 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase ApbA_C PF08546.6 EGO31026.1 - 1.8e-34 118.3 0.1 4.1e-34 117.2 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGO31026.1 - 4.7e-24 84.5 0.1 2e-23 82.5 0.1 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EGO31026.1 - 0.021 14.8 0.0 0.088 12.8 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.16 EGO31027.1 - 6.7e-46 156.3 0.0 7.8e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 EGO31029.1 - 3.7e-07 29.7 2.6 8.6e-07 28.5 1.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO31029.1 - 0.16 11.7 2.8 2.3 7.9 1.9 2.5 1 1 0 1 1 1 0 F-box domain Homeobox PF00046.24 EGO31030.1 - 9e-14 50.8 2.3 5.2e-13 48.3 0.7 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EGO31030.1 - 0.00028 20.5 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain SR-25 PF10500.4 EGO31030.1 - 1.3 8.4 6.5 2.6 7.4 4.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homeobox PF00046.24 EGO31031.1 - 4.9e-15 54.8 2.6 9.4e-15 53.9 1.8 1.5 1 0 0 1 1 1 1 Homeobox domain WD40 PF00400.27 EGO31032.1 - 9.4e-17 60.1 6.3 0.0024 17.6 0.1 6.6 6 1 1 7 7 7 4 WD domain, G-beta repeat DUF2956 PF11169.3 EGO31032.1 - 9 6.3 9.0 89 3.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2956) Methyltransf_11 PF08241.7 EGO31033.1 - 7.7e-11 42.3 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO31033.1 - 8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO31033.1 - 2.4e-08 34.5 0.0 4.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO31033.1 - 1e-06 28.9 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO31033.1 - 3.4e-06 26.3 0.0 1.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO31033.1 - 3.8e-05 23.3 0.0 0.0001 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO31033.1 - 0.00021 21.2 0.0 0.00056 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO31033.1 - 0.0003 19.9 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EGO31033.1 - 0.00037 20.9 0.0 0.00068 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO31033.1 - 0.00068 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.11 EGO31033.1 - 0.0074 14.6 0.0 0.012 13.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 EGO31033.1 - 0.052 12.7 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EGO31033.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Amidase02_C PF12123.3 EGO31035.1 - 0.006 16.2 0.1 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 N-acetylmuramoyl-l-alanine amidase Endonuc-dimeris PF09124.5 EGO31035.1 - 0.061 12.9 0.7 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation DDE_Tnp_4 PF13359.1 EGO31036.1 - 8.3e-15 54.7 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyr_redox PF00070.22 EGO31037.1 - 2e-16 60.1 0.6 1.8e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO31037.1 - 5.2e-14 52.5 0.0 1.8e-13 50.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO31037.1 - 7.1e-09 36.0 0.1 6.8e-05 23.0 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO31037.1 - 1.6e-07 30.5 3.8 0.0078 15.1 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO31037.1 - 1.1e-05 24.6 0.8 0.05 12.5 0.1 3.3 3 1 1 4 4 4 2 Lycopene cyclase protein K_oxygenase PF13434.1 EGO31037.1 - 4.4e-05 22.5 0.0 0.14 11.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO31037.1 - 0.00029 20.6 2.6 0.046 13.5 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EGO31037.1 - 0.0015 18.6 0.1 0.51 10.4 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO31037.1 - 0.0043 17.2 0.1 0.8 9.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 EGO31037.1 - 0.0051 16.7 1.2 1.2 9.1 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain Glyco_hydro_3_C PF01915.17 EGO31037.1 - 0.04 13.4 0.2 0.073 12.5 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF4147 PF13660.1 EGO31037.1 - 0.042 12.9 0.2 2.2 7.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) NAD_binding_8 PF13450.1 EGO31037.1 - 0.051 13.6 1.0 0.93 9.5 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain CoA_binding_2 PF13380.1 EGO31037.1 - 0.063 13.4 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 1 0 CoA binding domain NAD_Gly3P_dh_N PF01210.18 EGO31037.1 - 0.067 12.9 0.1 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EGO31037.1 - 0.078 13.4 2.2 4.2 7.8 0.0 3.5 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF3530 PF12048.3 EGO31037.1 - 0.16 10.9 0.3 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Trp_halogenase PF04820.9 EGO31037.1 - 0.2 10.2 1.7 0.56 8.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EGO31037.1 - 0.3 9.9 6.8 12 4.6 0.1 4.0 4 1 1 5 5 5 0 Glucose inhibited division protein A ThiF PF00899.16 EGO31037.1 - 0.74 9.6 2.6 26 4.6 0.1 2.5 2 0 0 2 2 2 0 ThiF family MMR_HSR1 PF01926.18 EGO31038.1 - 1.5e-09 37.7 0.0 5e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO31038.1 - 0.00052 19.3 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGO31038.1 - 0.049 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arrestin_C PF02752.17 EGO31040.1 - 1.7e-13 50.8 0.0 4.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF1741 PF08427.5 EGO31042.1 - 1e-28 100.4 3.3 1.6e-28 99.7 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) GDC-P PF02347.11 EGO31043.1 - 1.2e-182 607.4 0.1 3.3e-173 576.3 0.0 3.1 2 1 1 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EGO31043.1 - 8.1e-05 21.9 0.1 0.00015 20.9 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGO31043.1 - 0.0022 16.8 0.3 0.017 13.8 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO31043.1 - 0.045 12.0 0.4 0.074 11.3 0.3 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PPR_2 PF13041.1 EGO31044.1 - 1.6e-23 82.3 0.2 0.078 12.9 0.0 10.6 9 2 2 11 11 11 8 PPR repeat family PPR PF01535.15 EGO31044.1 - 8.5e-11 41.0 6.7 0.99 9.5 0.2 7.8 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.2 EGO31044.1 - 6e-06 25.6 0.1 1.3 8.5 0.0 5.7 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.1 EGO31044.1 - 0.00012 22.1 3.5 14 6.2 0.0 7.1 8 0 0 8 8 8 1 Pentatricopeptide repeat domain SecE PF00584.15 EGO31046.1 - 2.2e-14 52.7 0.0 2.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Vps51 PF08700.6 EGO31048.1 - 6.4e-14 51.5 1.0 2.6e-13 49.6 0.7 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Flg_bbr_C PF06429.8 EGO31048.1 - 0.00047 20.0 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal DUF1751 PF08551.5 EGO31049.1 - 1.7e-26 92.4 5.5 3.1e-26 91.5 3.8 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGO31049.1 - 0.073 13.0 7.6 0.16 11.9 5.2 1.6 1 1 0 1 1 1 0 Rhomboid family DUF1754 PF08555.5 EGO31050.1 - 2.8e-13 50.2 3.7 2.8e-13 50.2 2.6 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Herpes_LP PF03363.8 EGO31050.1 - 0.0059 16.1 0.3 0.007 15.9 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus leader protein DUF4191 PF13829.1 EGO31050.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PP2C_C PF07830.8 EGO31050.1 - 0.039 14.0 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain CM_2 PF01817.16 EGO31050.1 - 0.36 10.9 3.1 4.9 7.3 0.2 2.1 2 0 0 2 2 2 0 Chorismate mutase type II DUF1192 PF06698.6 EGO31051.1 - 0.021 14.6 1.2 0.021 14.6 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Sipho_Gp157 PF05565.6 EGO31051.1 - 0.13 11.8 1.3 0.3 10.6 0.7 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 TMF_DNA_bd PF12329.3 EGO31051.1 - 0.38 10.5 5.5 0.16 11.7 2.2 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Peptidase_M3 PF01432.15 EGO31053.1 - 8.3e-130 433.8 0.0 1e-129 433.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF4218 PF13960.1 EGO31054.1 - 0.057 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) TMF_DNA_bd PF12329.3 EGO31054.1 - 0.26 11.0 0.3 0.51 10.1 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding F-protein PF00469.15 EGO31054.1 - 0.99 8.7 3.1 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef PapD_N PF00345.15 EGO31056.1 - 0.094 12.5 0.2 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Mating_C PF12737.2 EGO31057.1 - 1.2e-32 113.3 29.5 7.9e-31 107.3 20.5 2.3 1 1 0 1 1 1 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 EGO31057.1 - 9.4e-15 54.0 0.2 2.8e-14 52.5 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.2 EGO31057.1 - 1.4e-07 31.3 1.9 3.1e-07 30.1 1.3 1.7 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox PF00046.24 EGO31057.1 - 0.00061 19.3 0.0 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 Homeobox domain DASH_Dad2 PF08654.5 EGO31057.1 - 1.5 8.8 7.6 5.3 7.1 1.1 3.3 2 1 1 3 3 3 0 DASH complex subunit Dad2 Homeobox PF00046.24 EGO31058.1 - 1.2e-13 50.4 1.7 2.6e-13 49.3 1.2 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGO31058.1 - 3.8e-07 29.7 1.0 8e-07 28.6 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 EGO31058.1 - 0.00021 20.2 0.1 0.00056 18.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez ATP-synt_B PF00430.13 EGO31059.1 - 0.002 17.9 1.1 0.024 14.4 0.1 2.1 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) DUF883 PF05957.8 EGO31059.1 - 0.0029 17.9 2.8 0.024 15.0 0.1 2.5 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGO31059.1 - 0.031 13.7 0.2 0.067 12.6 0.1 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Glyco_transf_8 PF01501.15 EGO31060.1 - 1.2e-31 109.9 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGO31060.1 - 0.056 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative STE3 PF02076.10 EGO31061.1 - 1.2e-22 80.3 5.9 2.3e-21 76.1 4.1 2.0 1 1 0 1 1 1 1 Pheromone A receptor SAICAR_synt PF01259.13 EGO31062.1 - 3.7e-80 268.6 0.0 4.8e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Lys PF00062.15 EGO31064.1 - 0.11 12.4 0.4 0.23 11.4 0.1 1.5 1 1 1 2 2 2 0 C-type lysozyme/alpha-lactalbumin family Chitin_synth_1 PF01644.12 EGO31066.1 - 1e-76 256.2 0.6 1.5e-76 255.7 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGO31066.1 - 2.7e-25 87.8 0.0 7.8e-25 86.3 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGO31066.1 - 2.4e-24 85.6 0.1 2.1e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGO31066.1 - 1.5e-08 34.7 0.0 3.9e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGO31066.1 - 5.6e-08 32.7 6.0 5e-07 29.6 4.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Homeobox PF00046.24 EGO31067.1 - 2.9e-49 164.4 10.7 7e-17 60.8 0.1 3.4 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 EGO31067.1 - 4.2e-16 58.3 0.7 2.1e-05 24.1 0.0 3.8 3 0 0 3 3 3 3 Homeobox KN domain HTH_3 PF01381.17 EGO31067.1 - 0.00021 21.0 0.5 0.39 10.5 0.0 3.8 4 0 0 4 4 4 2 Helix-turn-helix Homez PF11569.3 EGO31067.1 - 0.0031 16.5 0.6 1.6 7.8 0.0 3.1 3 0 0 3 3 3 2 Homeodomain leucine-zipper encoding, Homez Fumble PF03630.9 EGO31068.1 - 3.3e-115 384.5 0.0 4e-88 295.5 0.1 3.0 3 0 0 3 3 3 3 Fumble Adaptin_N PF01602.15 EGO31069.1 - 5.5e-114 381.3 0.0 7.7e-114 380.8 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EGO31069.1 - 1.4e-58 196.9 3.3 3.4e-58 195.7 2.3 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EGO31069.1 - 1.6e-14 53.9 3.1 0.00069 19.8 0.1 6.6 3 2 4 7 7 7 3 HEAT repeats Arm PF00514.18 EGO31069.1 - 0.011 15.5 0.3 66 3.5 0.0 4.5 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGO31069.1 - 0.013 15.4 8.0 8.4 6.7 0.1 6.1 6 0 0 6 6 6 0 HEAT repeat HEAT_PBS PF03130.11 EGO31069.1 - 0.056 13.9 0.9 18 6.1 0.1 5.1 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Pkinase PF00069.20 EGO31070.1 - 7.4e-37 126.8 0.0 9.2e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO31070.1 - 5.6e-13 48.5 0.0 7.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO31070.1 - 5.9e-05 22.9 0.0 0.0026 17.5 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGO31070.1 - 0.027 13.2 0.1 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1912 PF08930.5 EGO31070.1 - 0.11 12.5 1.7 1 9.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) cNMP_binding PF00027.24 EGO31071.1 - 7.2e-41 137.9 0.1 2.2e-17 62.6 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EGO31071.1 - 4.6e-19 69.1 2.2 8.1e-13 48.7 0.7 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase Sec1 PF00995.18 EGO31072.1 - 3.9e-118 395.5 0.0 4.5e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SPOUT_MTase PF02590.12 EGO31072.1 - 0.12 12.0 0.0 19 4.9 0.0 2.4 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase YABBY PF04690.8 EGO31073.1 - 2.2e-07 31.3 0.3 2.3e-07 31.2 0.2 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.5 EGO31073.1 - 0.0014 18.9 1.2 0.0014 18.9 0.8 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 EGO31073.1 - 0.0045 17.2 2.7 0.0045 17.2 1.8 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box Pex19 PF04614.7 EGO31073.1 - 0.081 12.5 2.8 0.083 12.4 2.0 1.1 1 0 0 1 1 1 0 Pex19 protein family DUF1014 PF06244.7 EGO31073.1 - 0.33 11.1 5.0 0.52 10.5 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) F-box-like PF12937.2 EGO31074.1 - 3.6e-06 26.5 0.0 2e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EGO31074.1 - 0.018 15.0 10.9 0.44 10.7 0.1 5.5 7 0 0 7 7 7 0 Leucine Rich repeat F-box PF00646.28 EGO31074.1 - 0.06 13.0 1.2 2.6 7.8 0.0 3.6 3 0 0 3 3 3 0 F-box domain LRR_7 PF13504.1 EGO31074.1 - 7.9 7.1 6.9 23 5.7 0.1 5.1 4 1 0 4 4 4 0 Leucine rich repeat Sas10_Utp3 PF04000.10 EGO31076.1 - 7.9e-17 61.2 0.1 1.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SF3b10 PF07189.6 EGO31077.1 - 1.1e-32 111.6 0.0 1.4e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_11 PF08241.7 EGO31078.1 - 1.7e-09 38.0 0.0 3.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO31078.1 - 1.6e-06 28.3 0.0 5.5e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO31078.1 - 3.4e-06 26.8 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO31078.1 - 8.7e-06 26.1 0.0 3.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO31078.1 - 5.2e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO31078.1 - 0.0003 20.4 0.0 0.00085 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO31078.1 - 0.00033 19.8 0.0 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HTH_8 PF02954.14 EGO31078.1 - 0.014 14.9 2.3 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family MTS PF05175.9 EGO31078.1 - 0.11 11.8 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain WLM PF08325.5 EGO31079.1 - 1.8e-48 164.8 0.0 2.7e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EGO31079.1 - 3.8e-06 25.8 1.5 3.8e-06 25.8 1.1 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EGO31079.1 - 0.00015 21.6 0.6 0.00038 20.3 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF45 DZR PF12773.2 EGO31079.1 - 0.02 14.6 8.6 0.048 13.4 5.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EGO31079.1 - 0.2 11.2 11.6 4.7 6.8 0.1 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Methyltransf_16 PF10294.4 EGO31080.1 - 5.1e-05 22.7 0.1 7.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGO31080.1 - 0.017 14.4 0.1 0.038 13.3 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EGO31080.1 - 0.087 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Bot1p PF12298.3 EGO31081.1 - 1.2e-26 93.6 0.1 2.1e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 EGO31081.1 - 0.083 12.8 2.0 0.58 10.1 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial ribosomal protein subunit L20 MFS_1 PF07690.11 EGO31082.1 - 3.2e-20 72.1 23.5 4.8e-20 71.5 16.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.14 EGO31082.1 - 0.094 12.9 0.4 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Cpn60_TCP1 PF00118.19 EGO31083.1 - 4.4e-139 464.2 0.0 5e-139 464.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.18 EGO31084.1 - 2.3e-65 220.3 0.0 3.2e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EGO31084.1 - 2.2e-16 59.6 0.0 2.1e-15 56.5 0.0 2.5 3 0 0 3 3 3 1 HIRAN domain Helicase_C PF00271.26 EGO31084.1 - 1.1e-13 50.8 0.0 4.2e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO31084.1 - 6.9e-09 35.4 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO31084.1 - 3.4e-08 33.5 0.0 8.9e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 EGO31084.1 - 3.8e-07 30.0 14.9 9e-07 28.8 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO31084.1 - 1.3e-06 27.9 14.7 2.6e-06 26.9 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO31084.1 - 2.7e-06 27.1 14.0 5.6e-06 26.0 8.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO31084.1 - 0.00011 21.8 10.8 0.00019 21.0 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO31084.1 - 0.00029 20.6 14.6 0.0006 19.6 10.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EGO31084.1 - 0.0034 16.8 8.9 0.0065 15.9 6.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EGO31084.1 - 0.036 13.8 12.4 0.066 12.9 8.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 EGO31084.1 - 0.037 13.5 6.6 0.094 12.2 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ICL PF00463.16 EGO31085.1 - 4.9e-193 642.1 0.0 5.5e-193 641.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGO31085.1 - 7.6e-11 41.6 0.0 2.8e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase CsoSCA PF08936.5 EGO31087.1 - 0.014 13.7 0.0 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase HLH PF00010.21 EGO31089.1 - 3e-11 42.8 1.7 2.9e-10 39.6 0.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF342 PF03961.8 EGO31089.1 - 0.013 13.9 1.4 0.015 13.7 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mt_ATP-synt_B PF05405.9 EGO31089.1 - 0.016 14.6 1.8 0.02 14.3 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4482 PF14818.1 EGO31089.1 - 0.019 15.6 0.9 0.029 15.0 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Atg14 PF10186.4 EGO31089.1 - 0.044 12.7 5.5 0.054 12.4 3.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 EGO31089.1 - 0.14 11.7 2.9 0.13 11.8 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 EGO31089.1 - 0.23 11.3 6.6 0.3 10.9 4.6 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 EGO31089.1 - 0.28 10.3 3.7 0.13 11.4 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) EMP24_GP25L PF01105.19 EGO31089.1 - 0.47 10.1 2.2 0.59 9.8 1.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2968 PF11180.3 EGO31089.1 - 0.66 9.3 6.0 0.88 8.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 EGO31089.1 - 0.98 8.9 6.6 0.92 9.0 0.8 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 EGO31089.1 - 3.3 7.6 9.2 6 6.8 6.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 EGO31089.1 - 3.4 7.2 7.9 4.8 6.7 5.5 1.2 1 0 0 1 1 1 0 IncA protein HLH PF00010.21 EGO31092.1 - 5.9e-09 35.4 2.4 5.9e-09 35.4 1.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Orbi_VP5 PF00901.12 EGO31092.1 - 0.68 8.0 6.2 0.92 7.6 4.3 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TBCA PF02970.11 EGO31094.1 - 1.1e-19 70.2 6.7 2.3e-19 69.2 3.7 1.8 1 1 1 2 2 2 2 Tubulin binding cofactor A Med11 PF10280.4 EGO31095.1 - 0.034 14.2 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 Mediator complex protein Bromodomain PF00439.20 EGO31096.1 - 4.1e-56 186.8 0.2 4.2e-20 71.4 0.0 3.8 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 EGO31096.1 - 2.7e-15 56.3 0.4 8.5e-09 34.9 0.0 3.3 2 1 1 3 3 3 3 Peptidase family M1 Peptidase_MA_2 PF13485.1 EGO31096.1 - 0.0045 17.0 0.1 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase MA superfamily PIP5K PF01504.13 EGO31097.1 - 9.3e-66 221.4 0.2 1.6e-65 220.6 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EGO31097.1 - 4e-26 91.7 0.0 6e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EGO31097.1 - 0.0051 16.6 1.0 0.017 15.0 0.3 2.1 2 0 0 2 2 2 1 FYVE zinc finger Methyltransf_33 PF10017.4 EGO31098.1 - 1.8e-21 76.3 0.0 2.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent PCI PF01399.22 EGO31099.1 - 4.4e-17 62.3 1.0 1.5e-16 60.6 0.4 2.2 1 1 1 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGO31099.1 - 1.4e-09 37.8 0.2 2.9e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 MRP-L28 PF09812.4 EGO31100.1 - 1.8e-10 40.8 7.0 5.3e-08 32.8 2.9 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 Rsm22 PF09243.5 EGO31101.1 - 6.6e-44 149.9 0.0 4.2e-29 101.4 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.24 EGO31102.1 - 3.5e-29 101.7 0.0 5.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGO31102.1 - 4.1e-09 36.4 0.1 7.9e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein dsrm PF00035.20 EGO31104.1 - 4.4e-08 33.5 0.0 5.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 EGO31105.1 - 1.1e-07 32.2 0.0 2.1e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Double-stranded RNA binding motif MARVEL PF01284.18 EGO31107.1 - 1.2e-06 28.4 21.0 1.2e-06 28.4 14.6 1.6 1 1 1 2 2 2 1 Membrane-associating domain ODV-E18 PF10717.4 EGO31107.1 - 0.027 13.8 0.5 0.79 9.2 0.0 2.5 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 UL73_N PF12522.3 EGO31107.1 - 1.3 8.5 7.9 0.085 12.4 1.4 2.2 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Nodulin_late PF07127.6 EGO31107.1 - 4 7.6 6.3 1.5 9.0 0.3 2.4 2 0 0 2 2 2 0 Late nodulin protein WD40 PF00400.27 EGO31108.1 - 1.6e-54 179.8 22.0 7.8e-09 35.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGO31108.1 - 0.00038 20.2 0.0 0.14 11.8 0.0 2.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF1730 PF08331.5 EGO31109.1 - 0.017 14.8 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) DUF3037 PF11236.3 EGO31109.1 - 0.06 13.4 0.0 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DUF837 PF05769.6 EGO31114.1 - 1.5e-06 27.9 6.8 9.8e-06 25.2 2.8 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF837) DUF535 PF04393.8 EGO31114.1 - 0.026 13.4 1.7 0.056 12.3 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF535) NYD-SP28_assoc PF14775.1 EGO31114.1 - 0.63 9.7 7.4 1.7 8.3 0.3 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain BAF1_ABF1 PF04684.8 EGO31114.1 - 2.1 7.1 7.0 3.5 6.3 4.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2414 PF10309.4 EGO31115.1 - 5.2e-06 26.0 0.0 8.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EGO31115.1 - 0.00054 19.8 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain HTH_17 PF12728.2 EGO31117.1 - 0.00056 20.1 0.0 0.00063 19.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_23 PF13489.1 EGO31118.1 - 4.2e-09 36.3 0.0 5.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO31118.1 - 6.3e-08 33.1 0.1 8.8e-07 29.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO31118.1 - 1e-07 32.3 0.0 3.3e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO31118.1 - 3.3e-07 30.0 0.0 5.8e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO31118.1 - 6.2e-06 26.6 0.0 3.3e-05 24.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO31118.1 - 0.00017 20.7 0.0 0.00047 19.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EGO31118.1 - 0.00018 21.5 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EGO31118.1 - 0.00032 21.0 0.1 0.0047 17.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGO31118.1 - 0.0079 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO31118.1 - 0.0079 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EGO31118.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 EGO31118.1 - 0.018 15.0 0.0 0.32 11.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGO31118.1 - 0.064 12.3 0.0 0.43 9.6 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EGO31118.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase DSHCT PF08148.7 EGO31119.1 - 4e-61 205.3 1.1 7.2e-61 204.5 0.3 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EGO31119.1 - 8.3e-22 77.4 0.1 2e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EGO31119.1 - 4.5e-06 26.0 0.1 7.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EGO31119.1 - 2.1e-05 24.3 0.0 7.2e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO31119.1 - 0.031 14.1 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.1 EGO31122.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO31122.1 - 5.1e-06 26.8 0.0 1.4e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO31122.1 - 5.4e-05 23.7 0.1 0.00059 20.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO31122.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EGO31122.1 - 0.00016 20.7 0.0 0.00064 18.8 0.0 1.9 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 EGO31122.1 - 0.00043 19.9 0.0 0.0058 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO31122.1 - 0.00078 19.8 0.0 0.0026 18.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO31122.1 - 0.021 15.1 0.0 0.075 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGO31122.1 - 0.041 13.0 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO31122.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Vps53_N PF04100.7 EGO31122.1 - 0.12 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Methyltransf_2 PF00891.13 EGO31122.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ist1 PF03398.9 EGO31124.1 - 4.6e-32 110.7 0.0 6.9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cut8_N PF14482.1 EGO31127.1 - 0.064 13.2 0.5 0.064 13.2 0.4 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Cytochrom_D1 PF02239.11 EGO31128.1 - 0.03 12.6 0.0 0.035 12.4 0.0 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain RasGEF PF00617.14 EGO31129.1 - 1.2e-37 129.4 0.0 1.8e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO31129.1 - 9.4e-22 77.0 0.2 2.6e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 EGO31130.1 - 4.8e-58 195.1 0.1 5.5e-58 194.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO31130.1 - 1.4e-20 73.9 0.0 1.9e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO31130.1 - 4.8e-13 48.7 0.1 5.4e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO31130.1 - 1.1e-06 28.0 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGO31130.1 - 1.8e-06 27.5 0.0 3.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO31130.1 - 6.1e-06 26.1 0.0 8.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGO31130.1 - 0.041 13.0 0.1 0.086 12.0 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EGO31130.1 - 0.044 13.7 0.2 0.13 12.2 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EGO31130.1 - 0.051 12.7 0.1 0.14 11.2 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO31130.1 - 0.062 13.4 0.0 0.31 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Big_3_2 PF12245.3 EGO31130.1 - 0.077 12.5 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF89 PF01937.14 EGO31130.1 - 0.087 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 Response_reg PF00072.19 EGO31130.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain G-alpha PF00503.15 EGO31130.1 - 0.19 10.3 0.4 6.1 5.4 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit RRM_1 PF00076.17 EGO31131.1 - 1.1e-15 57.0 0.1 1.9e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO31131.1 - 5e-10 39.2 0.0 1.3e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO31131.1 - 1.9e-08 34.0 0.0 0.00031 20.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO31131.1 - 0.036 13.8 0.2 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1534 PF07551.6 EGO31131.1 - 0.2 11.2 2.5 0.59 9.7 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) MatE PF01554.13 EGO31132.1 - 1.6e-23 83.1 24.2 9.5e-13 48.0 4.0 3.1 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EGO31132.1 - 9.6e-06 25.4 1.8 9.6e-06 25.4 1.3 3.5 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain polyprenyl_synt PF00348.12 EGO31135.1 - 7e-48 162.7 0.0 7.5e-44 149.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Calreticulin PF00262.13 EGO31136.1 - 7.1e-150 498.7 8.7 9.7e-150 498.2 6.0 1.2 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.22 EGO31136.1 - 2.7e-42 144.3 0.1 4.4e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGO31136.1 - 8.9e-26 89.8 0.0 2.4e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGO31136.1 - 2.5e-20 72.1 0.0 4.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO31136.1 - 5.7e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO31136.1 - 3.1e-06 27.1 0.1 6.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EGO31136.1 - 4.7e-06 26.3 0.0 3.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 EGO31136.1 - 5e-06 27.0 0.1 1e-05 26.0 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGO31136.1 - 0.0058 15.8 0.1 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGO31136.1 - 0.009 15.8 1.6 0.65 9.7 0.1 2.8 2 1 1 3 3 3 1 Dynamin family Ras PF00071.17 EGO31136.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Ras family Prefoldin_2 PF01920.15 EGO31137.1 - 1.2e-16 60.3 6.9 1.5e-16 60.0 4.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 EGO31137.1 - 0.00048 20.0 1.1 0.00048 20.0 0.8 2.1 2 0 0 2 2 2 1 Tropomyosin like Mnd1 PF03962.10 EGO31137.1 - 0.055 13.1 5.3 0.065 12.8 3.6 1.0 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 EGO31137.1 - 0.063 13.2 7.7 0.093 12.6 5.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NCA2 PF08637.5 EGO31137.1 - 0.12 11.2 4.7 0.79 8.5 0.4 2.1 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 CorA PF01544.13 EGO31137.1 - 0.21 10.6 4.7 1.4 7.9 0.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein YlqD PF11068.3 EGO31137.1 - 0.44 10.5 8.2 1.9 8.5 1.5 2.1 2 0 0 2 2 2 0 YlqD protein TBPIP PF07106.8 EGO31137.1 - 5 6.6 9.5 0.52 9.8 0.7 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EGO31137.1 - 5.1 7.1 7.8 21 5.1 5.3 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4618 PF15397.1 EGO31137.1 - 7.2 5.8 11.6 0.61 9.3 1.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) ABC2_membrane PF01061.19 EGO31138.1 - 1e-69 233.9 57.1 1.6e-36 125.4 11.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGO31138.1 - 3.3e-32 111.6 0.0 3.8e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGO31138.1 - 2e-23 81.9 0.5 1.6e-16 59.8 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter cobW PF02492.14 EGO31138.1 - 2.2e-06 27.2 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EGO31138.1 - 8.1e-06 25.3 0.2 0.048 13.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGO31138.1 - 9.4e-06 25.8 0.3 0.27 11.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 EGO31138.1 - 3.2e-05 23.9 0.1 9.8e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EGO31138.1 - 7.7e-05 22.5 0.0 0.078 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGO31138.1 - 0.0015 18.4 0.1 0.22 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO31138.1 - 0.0038 18.0 0.0 0.16 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EGO31138.1 - 0.0061 16.1 0.4 3.1 7.4 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGO31138.1 - 0.0076 16.5 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO31138.1 - 0.0084 15.6 0.4 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO31138.1 - 0.0088 16.0 0.3 0.22 11.4 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EGO31138.1 - 0.018 14.2 0.0 0.094 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SMC_N PF02463.14 EGO31138.1 - 0.03 13.5 0.0 0.76 8.9 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EGO31138.1 - 0.044 13.9 0.0 7.7 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EGO31138.1 - 0.058 13.3 0.3 14 5.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 EGO31138.1 - 0.1 12.5 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGO31138.1 - 0.1 11.9 0.1 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGO31138.1 - 0.1 12.0 0.1 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EGO31138.1 - 0.11 12.2 1.5 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain DUF2450 PF10475.4 EGO31140.1 - 0.076 11.8 6.0 0.15 10.9 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF1664 PF07889.7 EGO31140.1 - 0.26 11.0 4.6 0.34 10.7 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EGO31140.1 - 0.34 11.2 12.2 2.6 8.4 1.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EGO31140.1 - 1.2 8.5 16.7 1.9 7.9 5.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 EGO31140.1 - 2.7 7.8 21.9 0.62 9.9 1.6 4.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding EF-hand_6 PF13405.1 EGO31141.1 - 4.3e-09 35.4 0.3 0.0041 16.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EGO31141.1 - 3.6e-08 33.4 3.6 7.7e-08 32.3 0.4 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EGO31141.1 - 2.1e-07 29.9 0.3 4.8e-06 25.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 EGO31141.1 - 1.3e-06 27.3 0.4 5.2e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EGO31141.1 - 0.00037 20.0 0.2 0.003 17.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair DUF2849 PF11011.3 EGO31141.1 - 0.19 12.0 1.6 3.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) Dopey_N PF04118.9 EGO31142.1 - 4.4e-111 370.5 5.3 2.4e-110 368.1 0.0 3.5 4 0 0 4 4 4 2 Dopey, N-terminal PK PF00224.16 EGO31142.1 - 0.18 10.4 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ATP-synt_E PF05680.7 EGO31145.1 - 5.5e-20 71.1 0.2 5.6e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain AvrE PF11725.3 EGO31145.1 - 0.046 10.7 0.4 0.05 10.6 0.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF349 PF03993.7 EGO31145.1 - 0.099 12.8 2.5 0.16 12.1 1.7 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) WD40 PF00400.27 EGO31146.1 - 5.3e-35 118.0 8.7 2.1e-08 33.7 0.3 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGO31146.1 - 5.4e-29 99.8 0.2 1.1e-28 98.8 0.2 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex PA_decarbox PF05870.6 EGO31146.1 - 0.04 13.3 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) RAMP4 PF06624.7 EGO31147.1 - 0.00064 19.2 0.1 0.00076 18.9 0.1 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3040 PF11239.3 EGO31147.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2431 PF10354.4 EGO31148.1 - 7.6e-40 136.5 0.0 2e-39 135.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) LCD1 PF09798.4 EGO31148.1 - 0.49 8.3 1.4 0.69 7.8 1.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Fip1 PF05182.8 EGO31149.1 - 1.5e-20 72.1 0.3 2.5e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 Fip1 motif adh_short PF00106.20 EGO31150.1 - 3.3e-12 46.6 3.5 1.9e-11 44.2 2.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO31150.1 - 1.1e-06 28.4 0.1 1.7e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO31150.1 - 2e-06 27.7 2.4 5.2e-06 26.4 1.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGO31150.1 - 0.00059 19.3 3.3 0.0065 15.9 2.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGO31150.1 - 0.0015 18.5 0.2 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EGO31150.1 - 0.024 13.3 0.0 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2305 PF10230.4 EGO31150.1 - 0.045 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ING PF12998.2 EGO31151.1 - 6e-14 52.2 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGO31151.1 - 1.4e-08 34.3 6.2 2.1e-08 33.7 4.3 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGO31151.1 - 0.11 11.8 2.3 0.18 11.1 1.6 1.3 1 0 0 1 1 1 0 PHD-finger SOG2 PF10428.4 EGO31151.1 - 1.1 7.8 10.6 1.7 7.1 7.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CPSF73-100_C PF11718.3 EGO31152.1 - 1.8 7.8 4.7 2.2 7.5 3.3 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MFS_1 PF07690.11 EGO31153.1 - 3.9e-20 71.8 27.4 6.2e-20 71.1 19.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RabGAP-TBC PF00566.13 EGO31155.1 - 9.3e-47 159.2 0.0 1.3e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.28 EGO31157.1 - 1.7e-06 27.5 0.1 1.7e-06 27.5 0.1 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGO31157.1 - 4.9e-05 22.9 1.0 0.00031 20.3 0.1 2.9 2 1 0 2 2 2 1 F-box-like ParA PF10609.4 EGO31158.1 - 9.1e-32 108.7 0.1 1.6e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGO31158.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGO31158.1 - 1.5e-07 31.4 0.1 1.8e-05 24.7 0.0 2.8 3 1 0 3 3 3 1 AAA domain ArsA_ATPase PF02374.10 EGO31158.1 - 7.1e-07 28.5 1.3 0.00019 20.6 0.1 3.0 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 EGO31158.1 - 1.6e-05 24.1 0.1 0.00096 18.3 0.0 2.1 2 0 0 2 2 2 2 ATPase MipZ AAA_22 PF13401.1 EGO31158.1 - 0.043 13.9 0.1 0.14 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EGO31161.1 - 0.0022 17.8 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_6 PF14259.1 EGO31162.1 - 7.5e-17 61.0 0.0 6.5e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO31162.1 - 2.3e-16 59.1 0.0 4.1e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO31162.1 - 4.2e-13 48.9 0.0 6.6e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.17 EGO31163.1 - 7.7e-22 76.8 0.2 1.1e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.12 EGO31164.1 - 2.8e-33 115.1 0.0 7.6e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Ribonuclease_T2 PF00445.13 EGO31165.1 - 5.2e-34 117.5 0.1 7.5e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF3312 PF11768.3 EGO31166.1 - 0.051 11.7 0.1 0.051 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Herpes_UL6 PF01763.11 EGO31168.1 - 0.065 11.4 0.1 0.12 10.5 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.5 EGO31168.1 - 0.51 10.4 2.2 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SURF1 PF02104.10 EGO31170.1 - 6.8e-59 199.2 0.0 8.6e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 SURF1 family PsbK PF02533.10 EGO31170.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component ANTH PF07651.11 EGO31171.1 - 1.6e-71 240.3 3.9 2.2e-71 239.8 0.0 2.9 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EGO31171.1 - 5e-62 208.3 6.4 5e-62 208.3 4.4 4.5 4 0 0 4 4 4 1 I/LWEQ domain ENTH PF01417.15 EGO31171.1 - 5.1e-07 29.5 0.6 5.6e-06 26.2 0.0 3.0 3 0 0 3 3 3 1 ENTH domain Ion_trans PF00520.26 EGO31175.1 - 1.8e-06 27.3 1.6 1.8e-06 27.3 1.1 1.4 2 0 0 2 2 2 1 Ion transport protein Epimerase PF01370.16 EGO31178.1 - 3.5e-12 46.2 0.0 1.9e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO31178.1 - 3.3e-11 42.6 0.0 3.5e-06 26.1 0.0 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGO31178.1 - 4.6e-11 41.9 0.0 7.2e-08 31.4 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO31178.1 - 6.5e-11 42.5 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO31178.1 - 0.00031 19.7 0.0 0.0026 16.7 0.0 2.3 2 1 1 3 3 3 1 Male sterility protein Saccharop_dh PF03435.13 EGO31178.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 EGO31178.1 - 0.036 13.9 0.1 0.065 13.1 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 EGO31178.1 - 0.077 12.2 0.1 0.16 11.1 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.17 EGO31178.1 - 0.087 13.3 0.1 0.33 11.4 0.0 2.0 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 EGO31178.1 - 0.09 12.4 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EGO31178.1 - 0.14 12.0 0.2 0.41 10.4 0.1 1.8 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 EGO31179.1 - 9.1e-47 159.4 31.4 9.1e-47 159.4 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO31179.1 - 1.7e-09 36.7 13.4 1.7e-09 36.7 9.3 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 EGO31179.1 - 2e-07 29.5 6.4 2e-07 29.5 4.4 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.8 EGO31179.1 - 5.9e-07 28.0 4.8 5.9e-07 28.0 3.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO31179.1 - 4.9e-06 25.2 5.7 4.9e-06 25.2 3.9 2.9 3 1 1 4 4 4 1 MFS/sugar transport protein ATG22 PF11700.3 EGO31179.1 - 0.0018 16.8 1.8 0.0018 16.8 1.3 3.1 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like HORMA PF02301.13 EGO31180.1 - 7.8e-21 74.5 0.0 9.6e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PX PF00787.19 EGO31181.1 - 2.1e-18 66.1 0.6 8.1e-18 64.2 0.3 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGO31181.1 - 5.2e-05 22.6 5.0 0.0021 17.3 2.5 2.5 1 1 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EGO31181.1 - 0.14 11.5 2.5 8.4 5.8 0.2 3.4 3 1 0 3 3 3 0 BAR domain Fructosamin_kin PF03881.9 EGO31182.1 - 3.1e-66 223.2 0.0 3.8e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGO31182.1 - 6.7e-10 39.1 0.0 1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Oxidored_FMN PF00724.15 EGO31183.1 - 3.2e-62 210.4 0.0 5.2e-62 209.8 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ABC1 PF03109.11 EGO31184.1 - 1.1e-22 80.1 0.0 2.2e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family MULE PF10551.4 EGO31186.1 - 0.0026 17.8 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.12 EGO31186.1 - 0.023 14.2 0.1 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Transposase F-box-like PF12937.2 EGO31189.1 - 3.3e-05 23.5 0.2 6.7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like Dor1 PF04124.7 EGO31193.1 - 1e-35 122.8 3.2 6.3e-28 97.2 3.2 2.4 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EGO31193.1 - 0.018 14.8 0.0 0.057 13.2 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 Sec5 PF15469.1 EGO31193.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 Exo70 PF03081.10 EGO31193.1 - 0.28 9.9 2.5 5.3 5.7 0.6 2.2 2 0 0 2 2 2 0 Exo70 exocyst complex subunit F-box-like PF12937.2 EGO31194.1 - 0.0095 15.6 0.4 0.033 13.9 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO31194.1 - 0.016 14.8 0.7 0.016 14.8 0.5 2.5 3 0 0 3 3 3 0 F-box domain zf-UBP PF02148.14 EGO31195.1 - 0.15 12.2 6.2 0.71 10.0 4.1 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Rep_fac_C PF08542.6 EGO31196.1 - 6.7e-23 80.4 0.0 1.7e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EGO31196.1 - 2.9e-12 46.9 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGO31196.1 - 9.9e-12 44.8 0.1 9.3e-10 38.3 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EGO31196.1 - 1.4e-07 31.4 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGO31196.1 - 4.9e-07 28.8 0.1 0.0062 15.2 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EGO31196.1 - 3.7e-06 27.0 0.1 5e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO31196.1 - 5.7e-06 26.5 0.1 0.0057 16.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.6 EGO31196.1 - 8.6e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO31196.1 - 2.5e-05 23.4 0.0 6.2e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EGO31196.1 - 0.00022 20.8 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EGO31196.1 - 0.00099 18.3 0.0 0.023 13.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EGO31196.1 - 0.0043 15.8 0.0 0.012 14.4 0.0 1.7 1 1 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 EGO31196.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EGO31196.1 - 0.0075 15.7 0.0 0.18 11.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain NTPase_1 PF03266.10 EGO31196.1 - 0.009 15.7 0.2 0.054 13.2 0.1 2.0 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.1 EGO31196.1 - 0.022 15.0 0.1 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 EGO31196.1 - 0.026 14.0 0.1 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 EGO31196.1 - 0.038 14.1 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase SRP54 PF00448.17 EGO31196.1 - 0.064 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.1 EGO31196.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGO31196.1 - 0.082 12.3 0.1 0.82 9.1 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EGO31196.1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EGO31196.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EGO31196.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2b PF00587.20 EGO31198.1 - 1e-24 87.0 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGO31198.1 - 6.7e-10 38.9 1.0 1.1e-09 38.3 0.7 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF241 PF03087.9 EGO31198.1 - 0.035 13.6 0.6 0.059 12.8 0.4 1.3 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Uds1 PF15456.1 EGO31198.1 - 0.09 12.7 1.7 0.19 11.7 1.2 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Abhydrolase_3 PF07859.8 EGO31200.1 - 1e-13 51.3 0.1 1.2e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO31200.1 - 5.9e-09 35.0 0.2 9.4e-09 34.3 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EGO31200.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO31200.1 - 0.021 14.5 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family HAD_2 PF13419.1 EGO31200.1 - 0.089 13.0 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase STE3 PF02076.10 EGO31201.1 - 8.8e-45 152.9 12.3 1e-44 152.7 8.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EGO31203.1 - 2.2e-67 227.1 17.4 2.7e-67 226.8 12.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4234 PF14018.1 EGO31204.1 - 0.14 11.9 2.7 0.29 10.8 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Sugar_tr PF00083.19 EGO31205.1 - 3.9e-121 404.7 18.0 4.9e-121 404.4 12.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO31205.1 - 1.2e-16 60.4 48.4 5.4e-16 58.2 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily nec1 PF10379.4 EGO31206.1 - 0.035 13.3 0.6 0.11 11.7 0.3 1.8 1 1 1 2 2 2 0 Virulence protein nec1 Flu_M2 PF00599.12 EGO31206.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Inositol_P PF00459.20 EGO31208.1 - 1.9e-67 227.4 0.0 2.2e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family G-alpha PF00503.15 EGO31209.1 - 5.4e-125 417.0 0.0 6.7e-125 416.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO31209.1 - 1.8e-13 50.0 0.1 2.2e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EGO31209.1 - 0.0015 18.0 0.1 0.0053 16.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGO31209.1 - 0.0028 17.1 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EGO31209.1 - 0.0078 15.6 0.0 2 7.7 0.0 2.7 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EGO31209.1 - 0.066 13.7 0.0 0.48 10.9 0.0 2.4 2 1 0 2 2 2 0 Miro-like protein DAP3 PF10236.4 EGO31209.1 - 0.067 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.7 EGO31209.1 - 0.1 11.7 0.9 4.9 6.2 0.1 2.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGO31209.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EGO31213.1 - 5e-120 401.1 17.9 5.7e-120 400.9 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO31213.1 - 6.7e-20 71.1 37.5 4.6e-18 65.0 14.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 EGO31214.1 - 2.8e-40 136.8 0.0 3.1e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DASH_Ask1 PF08655.5 EGO31215.1 - 8.1e-21 73.6 0.1 1.5e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Dus PF01207.12 EGO31216.1 - 1e-50 172.3 0.0 2e-50 171.3 0.0 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) XPC-binding PF09280.6 EGO31216.1 - 0.012 15.1 0.0 6.6 6.2 0.0 2.5 2 0 0 2 2 2 0 XPC-binding domain ADH_zinc_N PF00107.21 EGO31217.1 - 1.2e-14 53.9 0.0 2.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO31217.1 - 8.6e-09 35.1 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGO31217.1 - 0.021 15.7 0.0 0.043 14.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CPSase_L_D2 PF02786.12 EGO31218.1 - 3e-73 245.6 0.0 4.6e-73 244.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGO31218.1 - 5.4e-39 132.7 0.2 1.5e-38 131.3 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGO31218.1 - 1.2e-31 108.8 0.0 6.1e-31 106.5 0.0 2.2 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGO31218.1 - 4.8e-17 61.3 3.3 1e-16 60.3 2.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGO31218.1 - 1.1e-15 57.8 0.0 3e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGO31218.1 - 4.5e-14 51.9 0.0 1.6e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGO31218.1 - 1.5e-10 40.8 0.0 3.7e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGO31218.1 - 5.6e-10 38.8 0.1 2.2e-09 36.8 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGO31218.1 - 4.2e-07 29.5 1.1 0.00013 21.5 0.2 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.1 EGO31218.1 - 0.00013 21.5 0.7 0.014 15.1 0.3 2.7 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 EGO31218.1 - 0.00042 19.7 2.6 0.16 11.2 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EGO31218.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGO31218.1 - 0.0015 18.8 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 1 HlyD family secretion protein RimK PF08443.6 EGO31218.1 - 0.0018 17.7 0.0 0.0041 16.6 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EGO31218.1 - 0.0083 15.8 0.7 0.017 14.8 0.5 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein GARS_A PF01071.14 EGO31218.1 - 0.0094 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.6 EGO31218.1 - 0.011 14.9 0.5 0.018 14.2 0.4 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Toxin_59 PF15537.1 EGO31218.1 - 0.015 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 59 PYNP_C PF07831.8 EGO31218.1 - 0.078 12.4 1.5 0.39 10.1 0.2 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF3182 PF11379.3 EGO31218.1 - 0.094 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) DUF2118 PF09891.4 EGO31218.1 - 0.096 12.3 0.6 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 EGO31218.1 - 0.12 11.4 2.0 1.1 8.4 0.2 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Vps51 PF08700.6 EGO31220.1 - 2.3e-17 62.5 0.4 8.9e-17 60.7 0.3 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EGO31220.1 - 6.3e-06 26.0 1.7 6.3e-06 26.0 1.2 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Caleosin PF05042.8 EGO31220.1 - 0.037 13.5 0.0 2.4 7.6 0.0 2.4 1 1 1 2 2 2 0 Caleosin related protein DNA_methylase PF00145.12 EGO31222.1 - 1.5e-36 126.1 0.0 7.9e-36 123.8 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EGO31222.1 - 2.1e-17 62.9 0.0 6.3e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EGO31222.1 - 3.6e-11 42.9 0.0 7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Methyltransf_26 PF13659.1 EGO31222.1 - 3e-05 24.0 0.0 7.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase_Csub PF13950.1 EGO31222.1 - 0.071 13.0 0.7 0.97 9.4 0.1 3.0 3 0 0 3 3 3 0 UDP-glucose 4-epimerase C-term subunit Cons_hypoth95 PF03602.10 EGO31222.1 - 0.26 10.6 0.0 0.49 9.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pkinase PF00069.20 EGO31223.1 - 5.9e-72 241.9 0.0 7.3e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO31223.1 - 2.9e-31 108.4 0.0 3.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO31223.1 - 0.00028 20.0 0.0 0.0008 18.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO31223.1 - 0.00058 19.6 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO31223.1 - 0.0021 17.0 0.0 0.02 13.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EGO31223.1 - 0.021 14.1 0.1 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family NAD_binding_1 PF00175.16 EGO31224.1 - 2.4e-25 89.1 0.0 3.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO31224.1 - 1.3e-17 63.6 0.0 2.9e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGO31224.1 - 0.0003 20.7 0.0 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGO31224.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain UCH PF00443.24 EGO31225.1 - 3e-43 147.8 0.0 6.1e-43 146.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EGO31225.1 - 5.8e-25 86.4 1.0 5.9e-18 64.0 0.1 2.7 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EGO31225.1 - 5.1e-12 45.8 0.0 5.5e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase efThoc1 PF11957.3 EGO31226.1 - 4.2e-98 328.9 9.0 3.2e-93 312.8 0.2 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.16 EGO31226.1 - 2.1e-31 109.2 0.0 5.1e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGO31226.1 - 6e-23 80.5 0.0 1.9e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGO31226.1 - 5.1e-07 28.6 0.1 9.2e-07 27.8 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO31226.1 - 8.4e-07 28.1 0.1 1.6e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO31226.1 - 0.00031 19.7 0.0 0.00067 18.6 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Atrophin-1 PF03154.10 EGO31226.1 - 0.001 17.3 3.9 0.001 17.3 2.7 2.5 2 0 0 2 2 2 1 Atrophin-1 family NAD_binding_4 PF07993.7 EGO31226.1 - 0.0084 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGO31226.1 - 0.0089 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO31226.1 - 0.073 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 KR domain ECH PF00378.15 EGO31226.1 - 0.12 11.4 0.6 11 5.0 0.3 2.2 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Rotamase PF00639.16 EGO31227.1 - 4e-22 78.7 0.0 5.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGO31227.1 - 5.6e-18 65.3 0.0 7.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EGO31227.1 - 4.7e-09 35.9 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EGO31227.1 - 0.00025 21.6 0.0 0.00033 21.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MOSC_N PF03476.11 EGO31228.1 - 2.3e-16 59.6 0.0 3.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGO31228.1 - 4.5e-10 39.1 0.0 1.2e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 MOSC domain nlz1 PF12402.3 EGO31228.1 - 0.26 11.6 1.8 8.3 6.8 0.0 2.4 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 UCH PF00443.24 EGO31229.1 - 1.3e-50 171.9 0.4 1.5e-50 171.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO31229.1 - 1.5e-27 96.8 0.2 1.9e-27 96.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Med10 PF09748.4 EGO31229.1 - 0.0053 16.5 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 Transcription factor subunit Med10 of Mediator complex Peptidase_C98 PF15499.1 EGO31229.1 - 0.097 11.9 4.9 0.35 10.1 1.8 2.4 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MerR-DNA-bind PF09278.6 EGO31232.1 - 0.11 12.9 0.2 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 MerR, DNA binding APH PF01636.18 EGO31233.1 - 7.5e-13 48.7 0.4 1.1e-12 48.1 0.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO31233.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRM_1 PF00076.17 EGO31235.1 - 1.4e-17 63.0 0.0 2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO31235.1 - 3.4e-15 55.7 0.0 4.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO31235.1 - 3.9e-10 39.4 0.0 6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1115 PF06544.7 EGO31236.1 - 3.8e-08 33.0 0.0 7.9e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 EGO31236.1 - 0.021 14.7 0.1 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 RWD domain DUF726 PF05277.7 EGO31238.1 - 7.9e-120 399.8 0.4 1.1e-119 399.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EGO31238.1 - 0.00046 19.9 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO31238.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pro-NT_NN PF07421.6 EGO31238.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor SRP14 PF02290.10 EGO31239.1 - 1.9e-23 82.2 3.9 2.1e-23 82.0 0.1 2.1 2 0 0 2 2 2 1 Signal recognition particle 14kD protein gag_pre-integrs PF13976.1 EGO31239.1 - 0.096 12.3 0.2 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 GAG-pre-integrase domain TP_methylase PF00590.15 EGO31240.1 - 2.7e-40 138.3 0.9 2.7e-40 138.3 0.6 1.5 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EGO31240.1 - 0.0026 17.0 0.6 0.0049 16.1 0.4 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Pkinase PF00069.20 EGO31241.1 - 3.2e-21 75.6 0.0 4.6e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO31241.1 - 4.8e-15 55.3 0.0 5.7e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO31241.1 - 0.00094 18.2 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ank PF00023.25 EGO31242.1 - 2.7e-15 55.3 2.0 2.4e-06 27.0 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGO31242.1 - 1.9e-14 53.3 2.5 1.5e-06 28.2 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO31242.1 - 2e-14 53.7 0.5 1.9e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO31242.1 - 3.3e-13 49.7 0.8 1.5e-07 31.7 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO31242.1 - 9.5e-12 43.9 0.7 3.4e-05 23.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat p450 PF00067.17 EGO31243.1 - 1.3e-45 155.8 0.0 1.5e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.1 EGO31244.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease Tecti-min-caps PF09300.5 EGO31246.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Tectiviridae, minor capsid DIOX_N PF14226.1 EGO31248.1 - 1.7e-16 60.8 0.0 3.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO31248.1 - 1.4e-12 47.7 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD-oxidase_C PF02913.14 EGO31249.1 - 5.7e-50 169.9 0.0 7.4e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO31249.1 - 5.6e-35 119.8 0.4 9.8e-35 119.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.6 EGO31249.1 - 0.096 12.0 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 D-lactate dehydrogenase, membrane binding LSM PF01423.17 EGO31250.1 - 3.2e-17 61.8 0.3 4.2e-17 61.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SET PF00856.23 EGO31252.1 - 1.6e-09 38.2 0.2 5.1e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 SET domain DUF829 PF05705.9 EGO31253.1 - 0.067 12.8 0.2 0.073 12.7 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Rhomboid PF01694.17 EGO31254.1 - 3.7e-35 121.0 13.1 7.2e-35 120.1 9.1 1.5 1 0 0 1 1 1 1 Rhomboid family DUF4191 PF13829.1 EGO31254.1 - 3.5 6.6 5.0 1.7 7.6 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4191) WD40 PF00400.27 EGO31261.1 - 4.1e-165 530.5 56.4 7.9e-14 50.9 0.2 15.2 15 0 0 15 15 15 14 WD domain, G-beta repeat PD40 PF07676.7 EGO31261.1 - 1.4e-20 72.4 8.4 1.1 8.9 0.0 12.6 13 0 0 13 13 12 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EGO31261.1 - 2.7e-12 46.6 17.8 0.0004 19.8 0.1 5.9 2 2 3 6 6 6 5 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 EGO31261.1 - 9.5e-12 44.0 12.3 5.1 6.5 0.0 11.3 12 0 0 12 12 12 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EGO31261.1 - 4.2e-11 42.2 2.1 0.087 11.5 0.0 6.7 2 2 4 7 7 7 3 Nup133 N terminal like eIF2A PF08662.6 EGO31261.1 - 9.4e-11 41.7 0.0 0.098 12.3 0.0 4.6 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 EGO31261.1 - 2.7e-09 36.8 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EGO31261.1 - 1.5e-08 33.2 10.5 1.2 7.2 0.0 9.2 4 3 4 10 10 10 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGO31261.1 - 5.9e-06 25.5 9.2 0.33 9.9 0.0 8.0 3 2 4 8 8 8 1 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EGO31261.1 - 1.1e-05 23.9 0.0 0.13 10.4 0.0 4.9 5 1 1 6 6 6 1 Protein of unknown function (DUF3312) AAA_16 PF13191.1 EGO31261.1 - 1.4e-05 25.1 0.0 4.3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Peptidase_S9_N PF02897.10 EGO31261.1 - 0.00028 19.5 0.4 1.9 6.9 0.0 4.9 5 2 1 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA PF00004.24 EGO31261.1 - 0.0066 16.6 0.0 0.073 13.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO31261.1 - 0.0089 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGO31261.1 - 0.033 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGO31261.1 - 0.05 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO31261.1 - 0.056 12.2 0.0 0.92 8.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 EGO31261.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Me-amine-dh_H PF06433.6 EGO31261.1 - 0.099 11.2 0.0 0.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) RNA_helicase PF00910.17 EGO31261.1 - 0.16 12.1 0.0 0.51 10.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IIGP PF05049.8 EGO31261.1 - 0.53 9.0 0.0 0.92 8.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) p450 PF00067.17 EGO31262.1 - 3.6e-51 174.1 0.0 4.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EGO31263.1 - 1e-78 256.6 14.8 8.5e-11 41.3 0.1 9.4 9 0 0 9 9 9 8 WD domain, G-beta repeat Gmad1 PF10647.4 EGO31263.1 - 2.5e-07 30.3 2.3 0.0037 16.6 1.2 3.9 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EGO31263.1 - 1.4e-06 27.8 3.8 1.1 9.0 0.0 6.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat NACHT PF05729.7 EGO31263.1 - 4.9e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO31263.1 - 6.7e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.1 EGO31263.1 - 0.00044 19.7 0.6 0.0013 18.2 0.2 2.0 1 1 1 2 2 2 1 PQQ-like domain C2 PF00168.25 EGO31263.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.9 1 0 0 1 1 1 1 C2 domain APS_kinase PF01583.15 EGO31263.1 - 0.034 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 EGO31263.1 - 0.034 12.9 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.9 EGO31263.1 - 0.068 12.1 0.1 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.1 EGO31263.1 - 0.075 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGO31263.1 - 0.14 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EGO31263.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Torsin Fasciclin PF02469.17 EGO31264.1 - 3e-08 33.7 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Complex1_49kDa PF00346.14 EGO31265.1 - 9.8e-127 421.5 0.0 1.3e-126 421.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EGO31265.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase CIMR PF00878.13 EGO31266.1 - 3.8e-16 59.1 0.1 3.2e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EGO31266.1 - 8.5e-08 31.5 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EGO31266.1 - 0.00028 20.2 0.2 0.0025 17.1 0.2 2.4 1 1 0 1 1 1 1 Autophagy-related protein 27 Baculo_11_kDa PF06143.6 EGO31266.1 - 0.31 10.4 1.7 0.54 9.6 1.2 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Nramp PF01566.13 EGO31267.1 - 3.5e-88 295.7 19.5 2.6e-47 161.3 4.8 2.3 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Amidohydro_1 PF01979.15 EGO31270.1 - 1.7e-15 57.5 0.2 2.1e-15 57.2 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGO31270.1 - 3.8e-09 36.2 0.1 9.6e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGO31270.1 - 5.1e-08 33.2 0.2 1.2e-07 32.0 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO31270.1 - 3.3e-05 23.3 0.5 0.047 12.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Rrp15p PF07890.7 EGO31271.1 - 0.068 13.2 1.3 0.16 12.0 0.9 1.6 1 0 0 1 1 1 0 Rrp15p PUF PF00806.14 EGO31275.1 - 3.7e-19 67.0 1.6 9.6e-07 27.9 0.0 4.5 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat Peptidase_S10 PF00450.17 EGO31276.1 - 1.3e-76 258.4 0.0 1.7e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CENP-F_leu_zip PF10473.4 EGO31277.1 - 0.0044 16.8 17.2 0.84 9.4 0.7 3.1 3 0 0 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF484 PF04340.7 EGO31277.1 - 0.016 14.7 2.6 0.017 14.5 0.2 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF484 Heme_oxygenase PF01126.15 EGO31277.1 - 0.03 13.8 0.2 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Heme oxygenase Fez1 PF06818.10 EGO31277.1 - 0.045 13.7 11.5 0.07 13.1 7.9 1.3 1 1 0 1 1 1 0 Fez1 APG6 PF04111.7 EGO31277.1 - 0.38 9.7 10.5 0.031 13.3 2.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 CDC37_N PF03234.9 EGO31277.1 - 0.38 11.0 7.9 0.53 10.5 4.0 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Macoilin PF09726.4 EGO31277.1 - 0.58 8.3 7.7 0.1 10.8 1.7 2.0 2 0 0 2 2 2 0 Transmembrane protein DivIC PF04977.10 EGO31277.1 - 1.9 8.0 13.9 0.67 9.4 0.6 3.1 3 0 0 3 3 3 0 Septum formation initiator GAS PF13851.1 EGO31277.1 - 2.1 7.4 12.3 3.7 6.6 2.3 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mto2_bdg PF12808.2 EGO31277.1 - 2.4 8.3 10.5 0.7 10.0 1.2 3.1 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-MYND PF01753.13 EGO31278.1 - 1.3e-08 34.5 9.4 1.3e-08 34.5 6.5 1.9 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 EGO31278.1 - 0.11 11.8 2.9 0.26 10.6 2.0 1.6 1 0 0 1 1 1 0 Life-span regulatory factor zf-ribbon_3 PF13248.1 EGO31278.1 - 7.9 5.8 6.6 2.6 7.3 1.0 2.5 2 1 1 3 3 3 0 zinc-ribbon domain zf-MYND PF01753.13 EGO31279.1 - 3.5e-08 33.1 10.5 7.7e-08 32.0 7.3 1.6 1 0 0 1 1 1 1 MYND finger zf-CCHC PF00098.18 EGO31281.1 - 0.00026 20.7 3.4 0.00051 19.8 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGO31281.1 - 0.0026 17.8 0.1 0.0048 16.9 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF3739 PF12545.3 EGO31281.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein Glyco_hydro_3 PF00933.16 EGO31283.1 - 2.8e-59 200.5 0.0 4.1e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO31283.1 - 9.2e-52 175.8 0.0 1.5e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO31283.1 - 2.3e-23 81.9 0.3 4.5e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain rve PF00665.21 EGO31284.1 - 3.3e-24 85.2 0.0 1e-23 83.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EGO31284.1 - 1.1e-19 70.7 0.1 2.6e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EGO31284.1 - 2.2e-12 46.4 0.2 6e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EGO31284.1 - 2.4e-06 27.2 4.4 5.9e-06 25.9 3.1 1.8 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EGO31284.1 - 0.0002 21.3 0.2 1 9.3 0.0 3.2 2 1 1 3 3 3 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGO31284.1 - 0.00036 20.2 0.0 0.00092 18.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EGO31284.1 - 0.0033 17.4 0.2 0.0033 17.4 0.1 2.7 3 1 1 4 4 4 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EGO31284.1 - 0.0047 17.4 0.0 0.024 15.1 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease Herpes_UL55 PF04537.7 EGO31284.1 - 0.094 12.1 0.3 0.2 11.0 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus UL55 protein Sec63 PF02889.11 EGO31285.1 - 1.2e-19 70.7 0.0 9.7e-18 64.4 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EGO31285.1 - 1e-14 53.9 0.1 2.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Sel1 PF08238.7 EGO31286.1 - 5.8e-44 147.5 18.3 3.5e-08 33.8 0.0 7.7 8 0 0 8 8 8 7 Sel1 repeat RNA_pol_Rpb2_6 PF00562.23 EGO31287.1 - 9.9e-129 429.4 0.1 2e-128 428.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGO31287.1 - 1.7e-68 229.5 0.0 2.7e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGO31287.1 - 6.8e-48 162.6 0.5 1.6e-47 161.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGO31287.1 - 5.7e-29 100.2 0.0 1.4e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGO31287.1 - 7.9e-28 96.0 0.7 2.3e-27 94.6 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGO31287.1 - 1.4e-23 82.4 0.1 3e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGO31287.1 - 3.6e-22 78.0 0.2 7.8e-22 77.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MHC_II_alpha PF00993.15 EGO31287.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain